WorldWideScience

Sample records for spectator matter fragmentation

  1. Kinematical properties of spectator fragments in heavy-ion collisions at relativistic energies

    International Nuclear Information System (INIS)

    Bacquias, A.

    2008-07-01

    Contrary to central collisions experiments, some experiments are designed for the investigation of nuclear-matter properties thanks to spectator matter. These experiments concentrate their selection on events of peripheral and mid-peripheral collisions. Spectator matter is not subject to compression but is highly excited. The observables related to spectator fragments can then be used as probes on nuclear matter at low density in the case of mid-peripheral collisions. Recently, experiments with the Fragment Separator (FRS) at GSI have proven to be suited for yielding valuable complementary information to spectator matter studies. We will first give an overview of the types of reaction relevant for this study and the different features that condition the reaction mechanisms leading to fragmentation. In the second chapter, we will describe the experimental set-up used at the FRS and explain the role of each detector and the method to exploit these data at best. In the third chapter we will concentrate our efforts on kinematics data from a 136 Xe + Pb experiment at the energy of 1 GeV per nucleon. Experimental results come in the fourth chapter and they are interpreted and discussed in chapters 5, 6 and 7. We will first comment the shapes of the velocity spectra and discuss the link between observation and physical processes. The surprising fact that one has means to assess the centrality despite the low acceptance of the experimental set-up will be underlined. This new way of presenting the data will permit a new approach to the nucleon-nucleon cross-section, by making comparison with theoretical models possible. Eventually, we will concentrate on the width of the velocity spectra. After going through previous models and predictions we will present a new description of the reaction mechanisms and their influence on the kinematics of observed fragments, reliable for a very broad range of fragments. (A.C.)

  2. Inclusive projectile fragmentation in the spectator model

    International Nuclear Information System (INIS)

    Hussein, M.S.; McVoy, K.W.

    1985-01-01

    Crazing-angle single spectra for projectile fragments from nuclear collisions exhibit a broad peak centered near the beam velocity, suggesting that these observed fragments play only a 'spectator' role in the reaction. Using only this spectator assumption (but not DWBA), it is found that a 'prior form' formulation of the reaction leads, via closure, to a -type estimate of the inclusive spectator spectrum, thus relating it to the reaction cross section for the 'participant' with the target. It is shown explicitly that this expression includes an improved multi-channel version of the Udagawa-Tamura formula for the 'breakup-fusion' or incomplete fusion cross section, and identifies it as the fluctuation part of the participant-target reaction cross section. A Glauber-type estimate of the distorted wave functions which enter clearly shows how the width of the peak in the spectator spectrum arises from the 'Fermi motion' within the projectile, as in the simple Serber model, but is modified by the 'overlap geometry' of the collision. (Author) [pt

  3. Universality of spectator fragmentation at relativistic bombarding energies

    International Nuclear Information System (INIS)

    Schuettauf, A.; Woerner, A.

    1996-06-01

    Multi-fragment decays of 129 Xe, 197 Au, and 238 U projectiles in collisions with Be, C, Al, Cu, In, Au, and U targets at energies between E/A=400 MeV and 1000 MeV have been studied with the ALADIN forward-spectrometer at SIS. By adding an array of 84 Si-CsI(Tl) telescopes the solid-angle coverage of the setup was extended to θ lab =16 . This permitted the complete detection of fragments from the projectile-spectator source. The dominant feature of the systematic set of data is the Z bound universality that is obeyed by the fragment multiplicities and correlations. These observables are invariant with respect to the entrance channel if plotted as a function of Z bound , where Z bound is the sum of the atomic numbers Z i of all projectile fragments with Z i ≥2. No significant dependence on the bombarding energy nor on the target mass is observed. The dependence of the fragment multiplicity on the projectile mass follows a linear scaling law. The reasons for and the limits of the observed universality of spectator fragmentation are explored within the realm of the available data and with model studies. It is found that the universal properties should persist up to much higher bombarding energies than explored in this work and that they are consistent with universal features exhibited by the intranuclear cascade and statistical multifragmentation models. (orig.)

  4. The multifragmentation of spectator matter

    International Nuclear Information System (INIS)

    Gossiaux, P.B.; Puri, R.; Hartnack, Ch.; Aichelin, J.

    1997-01-01

    The first microscopic calculation of the spectator fragmentation observed in heavy ion reactions at relativistic energies is presented which reproduces the slope of the kinetic energy spectra of the fragments as well as their multiplicity, both measured by the ALADIN collaboration. It is shown that both observables are dominated by dynamical processes and that the system does not pass a state of thermal equilibrium. These findings question the recent conjecture that in these collisions a phase transition of first order, similar to that between water and vapor, can be observed. (K.A.)

  5. Characteristics of spectators in 4He nuclei fragmentation processes

    International Nuclear Information System (INIS)

    Bano, M.; Braun, H.; Futo, A.

    1984-10-01

    Characteristics were studieO of deuteron, 3 H and 3 He spectators emitted in 4 He-p interactions at 8.6 GeV/c incident momentum. A model using the Monte Carlo procedure is proposed which predicts the momentum distribution for a nucleon or a group of nucleons (d, 3 H, 3 He) in the 4 He nucleus and describes some properties of reaction channels with spectator emission. The predictions are compared with experimental data. Good agreement is obtained taking into account the influence of the experimental errors and of the binding energy between the fragments. (author)

  6. Participant and spectator scaling of spectator fragments in Au + Au and Cu + Cu collisions at √{sN N}=19.6 and 22.4 GeV

    Science.gov (United States)

    Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Chai, Z.; Chetluru, V.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Harnarine, I.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; McLeod, D.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Richardson, E.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Szostak, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Willhelm, D.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wyngaardt, S.; Wysłouch, B.; Phobos Collaboration

    2016-08-01

    Spectator fragments resulting from relativistic heavy ion collisions, consisting of single protons and neutrons along with groups of stable nuclear fragments up to nitrogen (Z =7 ), are measured in PHOBOS. These fragments are observed in Au+Au (√{sNN}=19.6 GeV ) and Cu+Cu (22.4 GeV) collisions at high pseudorapidity (η ). The dominant multiply-charged fragment is the tightly bound helium (α ), with lithium, beryllium, and boron all clearly seen as a function of collision centrality and pseudorapidity. We observe that in Cu+Cu collisions, it becomes much more favorable for the α fragments to be released than lithium. The yields of fragments approximately scale with the number of spectator nucleons, independent of the colliding ion. The shapes of the pseudorapidity distributions of fragments indicate that the average deflection of the fragments away from the beam direction increases for more central collisions. A detailed comparison of the shapes for α and lithium fragments indicates that the centrality dependence of the deflections favors a scaling with the number of participants in the collision.

  7. Collins fragmentation function for pions and kaons in a spectator model

    Energy Technology Data Exchange (ETDEWEB)

    Bacchetta, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Gamberg, L.P. [Penn State Univ., Berks, PA (United States). Dept. of Physics; Goldstein, G.R. [Tufts Univ., Medford, MA (United States). Dept. of Physics and Astronomy; Mukherjee, A. [Indian Institute of Technology Bombay, Mumbai (India). Physics Dept.

    2007-07-15

    We calculate the Collins fragmentation function in the framework of a spectator model with pseudoscalar pion-quark coupling and a Gaussian form factor at the vertex. We determine the model parameters by fitting the unpolarized fragmentation function for pions and kaons. We show that the Collins function for the pions in this model is in reasonable agreement with recent parametrizations obtained by fits of the available data. In addition, we compute for the first time the Collins function for the kaons. (orig.)

  8. The stochastic spectator

    Energy Technology Data Exchange (ETDEWEB)

    Hardwick, Robert J.; Vennin, Vincent; Wands, David [Institute of Cosmology and Gravitation, University of Portsmouth, Dennis Sciama Building, Burnaby Road, Portsmouth, PO1 3FX (United Kingdom); Byrnes, Christian T.; Torrado, Jesús, E-mail: robert.hardwick@port.ac.uk, E-mail: vincent.vennin@port.ac.uk, E-mail: c.byrnes@sussex.ac.uk, E-mail: jesus.torrado@sussex.ac.uk, E-mail: david.wands@port.ac.uk [Department of Physics and Astronomy, University of Sussex, Brighton BN1 9QH (United Kingdom)

    2017-10-01

    We study the stochastic distribution of spectator fields predicted in different slow-roll inflation backgrounds. Spectator fields have a negligible energy density during inflation but may play an important dynamical role later, even giving rise to primordial density perturbations within our observational horizon today. During de-Sitter expansion there is an equilibrium solution for the spectator field which is often used to estimate the stochastic distribution during slow-roll inflation. However slow roll only requires that the Hubble rate varies slowly compared to the Hubble time, while the time taken for the stochastic distribution to evolve to the de-Sitter equilibrium solution can be much longer than a Hubble time. We study both chaotic (monomial) and plateau inflaton potentials, with quadratic, quartic and axionic spectator fields. We give an adiabaticity condition for the spectator field distribution to relax to the de-Sitter equilibrium, and find that the de-Sitter approximation is never a reliable estimate for the typical distribution at the end of inflation for a quadratic spectator during monomial inflation. The existence of an adiabatic regime at early times can erase the dependence on initial conditions of the final distribution of field values. In these cases, spectator fields acquire sub-Planckian expectation values. Otherwise spectator fields may acquire much larger field displacements than suggested by the de-Sitter equilibrium solution. We quantify the information about initial conditions that can be obtained from the final field distribution. Our results may have important consequences for the viability of spectator models for the origin of structure, such as the simplest curvaton models.

  9. The stochastic spectator

    International Nuclear Information System (INIS)

    Hardwick, Robert J.; Vennin, Vincent; Wands, David; Byrnes, Christian T.; Torrado, Jesús

    2017-01-01

    We study the stochastic distribution of spectator fields predicted in different slow-roll inflation backgrounds. Spectator fields have a negligible energy density during inflation but may play an important dynamical role later, even giving rise to primordial density perturbations within our observational horizon today. During de-Sitter expansion there is an equilibrium solution for the spectator field which is often used to estimate the stochastic distribution during slow-roll inflation. However slow roll only requires that the Hubble rate varies slowly compared to the Hubble time, while the time taken for the stochastic distribution to evolve to the de-Sitter equilibrium solution can be much longer than a Hubble time. We study both chaotic (monomial) and plateau inflaton potentials, with quadratic, quartic and axionic spectator fields. We give an adiabaticity condition for the spectator field distribution to relax to the de-Sitter equilibrium, and find that the de-Sitter approximation is never a reliable estimate for the typical distribution at the end of inflation for a quadratic spectator during monomial inflation. The existence of an adiabatic regime at early times can erase the dependence on initial conditions of the final distribution of field values. In these cases, spectator fields acquire sub-Planckian expectation values. Otherwise spectator fields may acquire much larger field displacements than suggested by the de-Sitter equilibrium solution. We quantify the information about initial conditions that can be obtained from the final field distribution. Our results may have important consequences for the viability of spectator models for the origin of structure, such as the simplest curvaton models.

  10. Radiation hardness investigation of avalanche photodiodes for the Projectile Spectator Detector readout at the Compressed Baryonic Matter experiment

    Czech Academy of Sciences Publication Activity Database

    Kushpil, Vasilij; Mikhaylov, Vasily; Kushpil, Svetlana; Tlustý, Pavel; Svoboda, Ondřej; Kugler, Andrej

    2015-01-01

    Roč. 787, JUL (2015), s. 117-120 ISSN 0168-9002 R&D Projects: GA MŠk LG12007; GA MŠk LG14004; GA MŠk(CZ) LM2011019 Institutional support: RVO:61389005 Keywords : avalanche photodiodes * single protons detection * radiation hardness * neutron irradiation tests * compressed Baryonic Matter experiment * Projectile Spectator Detector Subject RIV: BG - Nuclear, Atomic and Molecular Physics , Colliders Impact factor: 1.200, year: 2015

  11. Target fragmentation in proton-nucleus and16O-nucleus reactions at 60 and 200 GeV/nucleon

    Science.gov (United States)

    Albrecht, R.; Awes, T. C.; Baktash, C.; Beckmann, P.; Claesson, G.; Berger, F.; Bock, R.; Dragon, L.; Ferguson, R. L.; Franz, A.; Garpman, S.; Glasow, R.; Gustafsson, H. Å.; Gutbrod, H. H.; Kampert, K. H.; Kolb, B. W.; Kristiansson, P.; Lee, I. Y.; Löhner, H.; Lund, I.; Obenshain, F. E.; Oskarsson, A.; Otterlund, I.; Peitzmann, T.; Persson, S.; Plasil, F.; Poskanzer, A. M.; Purschke, M.; Ritter, H. G.; Santo, R.; Schmidt, H. R.; Siemiarczuk, T.; Sorensen, S. P.; Stenlund, E.; Young, G. R.

    1988-03-01

    Target remnants with ZPlastic Ball detector. The excitation energy of the target spectator matter in central oxygen-induced collisions is found to be high enough to allow for complete disintegration of the target nucleus into fragments with Z<3. The average longitudinal momentum transfer per proton to the target in central collisions is considerably higher in the case of16O-induced reactions (≈300 MeV/c) than in proton-induced reactions (≈130 MeV/c). The baryon rapidity distributions are roughly in agreement with one-fluid hydrodynamical calculations at 60 GeV/nucleon16O+Au but are in disagreement at 200 GeV/nucleon, indicating the higher degree of transparency at the higher bombarding energy. Both, the transverse momenta of target spectators and the entropy produced in the target fragmentation region are compared to those attained in head-on collisions of two heavy nuclei at Bevalac energies. They are found to be comparable or do even exceed the values for the participant matter at beam energies of about 1 2 GeV/nucleon.

  12. Dark matter from gravitational particle production at reheating

    Energy Technology Data Exchange (ETDEWEB)

    Markkanen, Tommi [Department of Physics, King' s College London, Strand, London WC2R 2LS (United Kingdom); Nurmi, Sami, E-mail: tommi.markkanen@kcl.ac.uk, E-mail: sami.t.nurmi@jyu.fi [Department of Physics, University of Jyväskylä, P.O. Box 35, FI-40014 University of Jyväskylä (Finland)

    2017-02-01

    We show that curvature induced particle production at reheating generates adiabatic dark matter if there are non-minimally coupled spectator scalars weakly coupled to visible matter. The observed dark matter abundance implies an upper bound on spectator masses m and non-minimal coupling values ξ. For example, assuming quadratic inflation, instant reheating and a single spectator scalar with only gravitational couplings, the observed dark matter abundance is obtained for m ∼ 0.1 GeV and ξ ∼ 1. Larger mass and coupling values of the spectator are excluded as they would lead to overproduction of dark matter.

  13. Dark matter from gravitational particle production at reheating

    International Nuclear Information System (INIS)

    Markkanen, Tommi; Nurmi, Sami

    2017-01-01

    We show that curvature induced particle production at reheating generates adiabatic dark matter if there are non-minimally coupled spectator scalars weakly coupled to visible matter. The observed dark matter abundance implies an upper bound on spectator masses m and non-minimal coupling values ξ. For example, assuming quadratic inflation, instant reheating and a single spectator scalar with only gravitational couplings, the observed dark matter abundance is obtained for m ∼ 0.1 GeV and ξ ∼ 1. Larger mass and coupling values of the spectator are excluded as they would lead to overproduction of dark matter.

  14. Synchronized arousal between performers and related spectators in a fire-walking ritual

    DEFF Research Database (Denmark)

    Konvalinka, Ivana; Xygalatas, Dimitris; Bulbulia, Joseph

    2011-01-01

    during the 30-min ritual between fire-walkers and related spectators but not unrelated spectators. This indicates that the mediating mechanism may be informational, because participants and related observers had very different bodily behavior. This study demonstrates that a collective ritual may evoke......Collective rituals are present in all known societies, but their function is a matter of long-standing debates. Field observations suggest that they may enhance social cohesion and that their effects are not limited to those actively performing but affect the audience as well. Here we show...... synchronized arousal over time between active participants and bystanders. It links field observations to a physiological basis and offers a unique approach for the quantification of social effects on human physiology during real-world interactions....

  15. Spectator Effects during Leptogenesis in the Strong Washout Regime

    CERN Document Server

    Garbrecht, Bjorn

    2014-01-01

    By including spectator fields into the Boltzmann equations for Leptogenesis, we show that partially equilibrated spectator interactions can have a significant impact on the freeze-out value of the asymmetry in the strong washout regime. The final asymmetry is typically increased, since partially equilibrated spectators "hide" a part of the asymmetry from washout. We study examples with leptonic and non-leptonic spectator processes, assuming thermal initial conditions, and find up to 50% enhanced asymmetries compared to the limit of fully equilibrated spectators. Together with a comprehensive overview of the equilibration temperatures for various Standard Model processes, the numerical results indicate the ranges when the limiting cases of either fully equilibrated or negligible spectator fields are applicable and when they are not. Our findings also indicate an increased sensitivity to initial conditions and finite density corrections even in the strong washout regime.

  16. The Spectator in the Picture

    OpenAIRE

    Hopkins, Robert

    2001-01-01

    This paper considers whether pictures ever implicitly represent internal spectators of the scenes they depict, and what theoretical construal to offer of their doing so. Richard Wollheim's discussion (Painting as an Art, ch.3) is taken as the most sophisticated attempt to answer these questions. I argue that Wollheim does not provide convincing argument for his claim that some pictures implicitly represent an internal spectator with whom the viewer of the picture is to imaginatively identify....

  17. Parton Propagation and Fragmentation in QCD Matter

    Energy Technology Data Exchange (ETDEWEB)

    Alberto Accardi, Francois Arleo, William Brooks, David D' Enterria, Valeria Muccifora

    2009-12-01

    We review recent progress in the study of parton propagation, interaction and fragmentation in both cold and hot strongly interacting matter. Experimental highlights on high-energy hadron production in deep inelastic lepton-nucleus scattering, proton-nucleus and heavy-ion collisions, as well as Drell-Yan processes in hadron-nucleus collisions are presented. The existing theoretical frameworks for describing the in-medium interaction of energetic partons and the space-time evolution of their fragmentation into hadrons are discussed and confronted to experimental data. We conclude with a list of theoretical and experimental open issues, and a brief description of future relevant experiments and facilities.

  18. Designing Technology for Active Spectator Experiences at Sporting Events

    DEFF Research Database (Denmark)

    Veerasawmy, Rune; Ludvigsen, Martin

    2010-01-01

    This paper explores the active spectator experience at sporting events, by presenting and reflecting upon a design experiment carried out at a number of football1 events. The initial hypothesis of the design process, leading to the design experiment has been that the spectator experience is not m......This paper explores the active spectator experience at sporting events, by presenting and reflecting upon a design experiment carried out at a number of football1 events. The initial hypothesis of the design process, leading to the design experiment has been that the spectator experience...... is not merely an experience of receiving and consuming entertainment. It is also heavily reliant on the active participation of the spectator in creating the atmosphere of the entire event. The BannerBattle experiment provides interactive technology in sport arenas with a form of interaction based on existing...

  19. Female Spectator Satisfaction and Perceived Service Quality on ...

    African Journals Online (AJOL)

    Female Spectator Satisfaction and Perceived Service Quality on University Sporting Grounds. ... study a survey was distributed to female spectators who watched soccer and basketball games on the grounds of ... AJOL African Journals Online.

  20. Fragmentation and flow in central collisions

    International Nuclear Information System (INIS)

    Jacak, B.V.; Doss, K.G.R.; Gustafsson, H.A.

    1987-01-01

    Investigation of the fragmentation mechanism requires the measurement of complicated observables. To identify what part of the reacting system gives rise to the fragments, it would be useful to tag them as participants or spectators. A large acceptance for all the reaction products and an event-by-event measurement of the fragment multiplicity is required to distinguish fragment formation via sequential emission from a large equilibrated system and multifragmentation. In order to address whether fragments are formed early or late in the collision, information about the dynamical evolution of the reaction is necessary. This can be provided by study of the global properties of the events. This paper discusses experimental techniques applicable to studying fragmentation processes. 25 refs., 8 figs

  1. A Ten-Value-Type Framework Associated With Spectator Sports

    Directory of Open Access Journals (Sweden)

    Li-Shiue Gau

    2013-04-01

    Full Text Available Prior value studies in sport settings have been focused on participation rather than spectatorship. This study is an initial step in examining the values associated with spectator sports. Interviews and focus groups were utilized in this qualitative study within four progressive phases for triangulation, transferability, and constant comparative assessment. A total of 54 individuals participated in the study. Because values were subjectively perceived at the highest level of abstraction reflecting desirable preference experiences, the interviews were designed to include seven categories of questions: Three categories dealt with observed behaviors and implied metaphors, and four categories including questions comparing spectator sports and sport participation, religion, other leisure activities, and substitutes. Grounded data techniques guided the coding procedure. Using the transcriptions and notes from 26 interviews and three focus groups, five coders were used to provide evidence of interrater reliability. Based on the results of the data analyses, a 10-value-type framework was developed in relation to spectator sports: (a Enjoyment (pleasure and satisfaction, (b Sociability (social interaction through sport spectating, (c Identity (enhancing self-esteem, (d Status (pursuing social recognition, (e Moral, (f Spirituality (inner peace, strength, meaning, and purpose in life, (g Epistemic, (h Aesthetics, (i Ritual (sports spectating becomes a series of formal and serious acts followed regularly and invariably as end-experience, and (j no or negative values. Different from Kahle’s (1983, Maslow’s (1970a, and Schwartz’ (1992 value theories, the framework was specifically associated with spectator sports and is expected to better predict spectator sport behavior than does a scale measuring motivations of sports fans.

  2. First order phase transition of expanding matter and its fragmentation

    International Nuclear Information System (INIS)

    Chikazumi, Shinpei; Iwamoto, Akira

    2002-01-01

    Using an expanding matter model with a Lennard-Jones potential, the instability of the expanding system is investigated. The pressure, the temperature, and the density fluctuations are calculated as functions of density during the time evolution of the expanding matter, which are compared to the coexistence curve calculated by the Gibbs ensemble. The expanding matter undergoes the first order phase transition in the limit of the quasistatic expansion. The resultant fragment mass distributions are also investigated. (author)

  3. Target fragmentation in proton-nucleus and /sup 16/O-nucleus reactions at 60 and 200 GeVnucleon

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, H R; Albrecht, R; Awes, T C; Baktash, C; Beckmann, P; Claesson, G; Berger, F; Bock, R; Dragon, L; Ferguson, R L; Franz, A; Garpman, S; Glasow, R; Gustafsson, H A; Gutbrod, H H; Kampert, K H; Kolb, B W; Kristiansson, P; Lee, I Y; Loehner, H; Lund, I; Obenshain, F E; Oskarsson, A; Otterlund, I; Peitzmann, T; Persson, S; Plasil, F; Poskanzer, A M; Purschke, M; Ritter, H G; Santo, R; Siemiarczuk, T; Sorensen, S P; Stenlund, E; Young, G R

    1987-01-01

    Target remnants with Z<3 from proton-nucleus and /sup 16/O-nulceus reactions at 60 and 200 GeVnucleon were measured in the angular range from 30)degree) to 160)degree) (-1.7<)eta)1.3) employing the Plastic Ball detector. The excitation energy of the target spectator matter in central oxygen-induced collisions is found to be high enough to allow for complete disintegration of the target nucelus into fragments with Z<3. The average longtitudinal momentum transfer per proton to the target in central collisions is considerably higher in the case of /sup 16/O-induced reactions (approx.300 MeVc) than in proton-induced reactions (approx.130 MeVc). The baryon rapidity distributions are roughly in agreement with one-fluid hydrodynamical calcualtions at 60 GeVnucleon /sup 16/O)plus)Au but are in disagreement at 200 GeVnucleon, indicating the higher degree of transparency at the higher bombarding energy. Both, the transverse moments of target spectators and the entropy produced in the target gfragmentation region are compared to those attained in head-on collisions of two heavy nuclei at Bevalac energies. They are found to be comparable or do even exceed the values for the participant matter at beam energies of about 1-2 GeVnucleon. 18 refs., 112 figs

  4. Momentum characteristics of spectators in fragmentation of 4He nuclei

    International Nuclear Information System (INIS)

    Glagolev, V.V.; Lebedev, R.M.; Strel'tsov, V.N.

    1985-01-01

    Some characteristics of 2 H, 3 H, 3 He fragments from 4 Hep interaction at 8.6 GeV/c have been studied. A numerical procedure, based on Monte-Carlo method, for getting the wave function of relative motion of nucleons or groups of nucleons in nucleus is proposed to describe the fragment momentum spectra and the asymmetry in Treiman-Yang angle distribution. The agreement between computed and experimental results is sufficient if one takes into account the experimental errors and the nucleus binding energy

  5. Charge conjugation invariance of the spectator equations

    International Nuclear Information System (INIS)

    Gross, F.

    1999-01-01

    In response to recent criticism, the authors show how to define the spectator equations for negative energies so that charge conjugation invariance is preserved. The result, which emerges naturally from the application of spectator principles to systems of particles with negative energies, is to replace all factors of the external energies W iota by √ W 2 iota , insuring that the amplitudes are independent of the sign of the energies W iota

  6. Fragmentation in peripheral heavy-ion collisions: from neck emission to spectator decays

    Energy Technology Data Exchange (ETDEWEB)

    Lukasik, J.; Auger, G.; Begemann-Blaich, M.L.; Bellaize, N.; Bittiger, R.; Bocage, F.; Borderie, B.; Bougault, R.; Bouriquet, B.; Charvet, J.L.; Chbihi, A.; Dayras, R.; Durand, D.; Frankland, J.D.; Galichet, E.; Gourio, D.; Guinet, D.; Hudan, S.; Hurst, B.; Lautesse, P.; Lavaud, F.; Le Fevre, A.; Legrain, R.; Lopez, O.; Lynen, U.; Mueller, W.F.J.; Nalpas, L.; Orth, H.; Plagnol, E.; Rosato, E.; Saija, A.; Schwarz, C.; Sfienti, C.; Steckmeyer, J.C.; Tamain, B.; Trautmann, W.; Trzcinski, A.; Turzo, K.; Vient, E.; Vigilante, M.; Volant, C.; Zwieglinski, B.; Botvina, A.S

    2003-07-24

    Invariant cross sections of intermediate mass fragments in peripheral collisions of {sup 197}Au on {sup 197}Au at incident energies between 40 and 150 MeV per nucleon have been measured with the 4{pi} multi-detector INDRA. The maximum of the fragment production is located near mid-rapidity at the lower energies and moves gradually towards the projectile and target rapidities as the energy is increased. Schematic calculations within an extended Goldhaber model suggest that the observed cross section distributions and their evolution with energy are predominantly the result of the clustering requirement for the emerging fragments and of their Coulomb repulsion from the projectile and target residues. The quantitative comparison with transverse energy spectra and fragment charge distributions emphasizes the role of hard scattered nucleons in the fragmentation process.

  7. Publicizing female athletes' weights: implications for female psychology undergraduates acting as spectators.

    Science.gov (United States)

    Holm-Denoma, Jill; Smith, April; Waesche, Matthew

    2014-09-01

    The purpose of this study was to examine the effects of including female athletes' weights in athletic event programs on female spectators' body image, eating disorder symptoms, self-esteem, and affective state and to investigate whether the magnitude of the athletes' reported weights had differential effects on female spectators (i.e., do female spectators who view heavier athletes respond differently than those who view less heavy athletes?). We used an experimental design to examine hypotheses derived from competing theories to determine whether exposure to female athletes of varying weight would adversely or beneficially impact female undergraduates (N = 152) who served as athletic event spectators. Analyses indicated that in this simulated study, female spectators' body image, eating disorder symptoms, self-esteem, and affective states were not impacted by the presence or by the magnitude of female athletes' weights in athletic event programs. The results imply that including athletes' weights in game-day programs at women's athletic events does not affect female spectators on an individual level.

  8. Fragmentation and direct transfer reactions for 40Ar incident beam on 27Al target at 1760 MeV

    International Nuclear Information System (INIS)

    Cisse, Ousmane

    1985-01-01

    Peripheral collision studies performed with 40 Ar projectiles at 44 MeV/A and 27 Al target show that both fragmentation and transfer reactions can be discerned in this type of interaction. The experimental observation of fragments with masses charges and velocities close to those of the incident beam are the signature of transfer reactions and a detailed analysis of the energy spectra of such fragments has been carried out and interpreted in terms of a direct diffraction transfer model. On the other hand, for large mass transfer reactions, abrasion is the suitable mechanism. Inclusive fragment measurement together with the appropriate residual nuclei-fragment coincidence results then provides experimental data in good agreement with the theoretical predictions obtained from a participant spectator model. These investigations also indicate that the separation energies of the participant from the spectator nucleus, at least within the framework of the above model, can be interpreted in terms of a friction force which becomes more efficient as the projectile energy decreases. (author) [fr

  9. Fragmentation processes in nuclear reactions

    International Nuclear Information System (INIS)

    Baur, G.; Roesel, F.; Trautmann, D.; Shyam, R.

    1983-10-01

    Fragmentation processes in nuclear collisions are reviewed. The main emphasis is put on light ion breakup at nonrelativistic energies. The post- and prior-form DWBA theories are discussed. The post-form DWBA, appropriate for the ''spectator breakup'' describes elastic as well as inelastic breakup modes. This theory can also account for the stripping to unbound states. The theoretical models are compared to typical experimental results to illustrate the various possible mechanisms. It is discussed, how breakup reactions can be used to study high-lying single particle strength in the continuum; how it can yield information about momentum distributions of fragments in the nucleus. (orig.)

  10. Projectile fragmentation processes in 35-MeV/amu (α,xy) reactions

    International Nuclear Information System (INIS)

    Koontz, R.W.; Chang, C.C.; Holmgren, H.D.; Wu, J.R.

    1979-01-01

    Coincidence measurements with 35-MeV/amu α particles show that at least three projectile-fragmentation processes occur. The dominant process is ''absorptive'' breakup, where one component of the projectile interacts strongly with the target resulting in the emission of evaporation or nonstatistical particles while the other component behaves as a spectator. The other fragmentation processes which are observed account for only a few percent of the breakup cross section

  11. An Empirical Exploration of Relationships Between Personal Values and Spectator Sport Consumption

    OpenAIRE

    Li-Shiue Gau; Jeffrey D. James

    2014-01-01

    This study examined relationships between personal life values and spectator sport consumption. From Kahle (1983), Rokeach (1973), and Schwartz (1992, 1996) value systems, twenty-eight personal values were identified probably relevant to spectator sport consumption for inclusion in a survey. A questionnaire was designed to assess the importance of each value and the frequency of spectator sport consumption. The questionnaires were administered through which 384 participants rated the importan...

  12. Football match spectator sound exposure and effect on hearing: A ...

    African Journals Online (AJOL)

    This was a one-group pretest–post-test design of football spectators attending a premier soccer league match at a designated FIFA 2010 training stadium in Gauteng, South Africa. Individual spectator noise exposure for the duration of the football match and post-match changes in hearing thresholds were measured with ...

  13. The role of the spectator assumption in models for projectile fragmentation

    International Nuclear Information System (INIS)

    Mc Voy, K.W.

    1984-01-01

    This review is restricted to direct-reaction models for the production of projectile fragments in nuclear collisions, at beam energies of 10 or more MeV/nucleon. Projectile fragments are normally identified as those which have near-beam velocities, and there seem to be two principal mechanisms for the production of these fast particles: 1. Direct breakup, 2. Sequential breakup. Of the two, the authors exclude from their discussion the ''sequential breakup'' process, in which the projectile is excited by the initial collision (either via inelastic scattering or transfer to unbound states) and then subsequently decays, outside the range of interaction

  14. Production of spectator hypermatter in relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Botvina, A. S.; Gudima, K. K.; Steinheimer, J.; Bleicher, M.; Mishustin, I. N.

    2011-01-01

    Possible formation of large hyperfragments in relativistic heavy-ion collisions is studied within two transport models, the Dubna cascade model and UrQMD model. Our goal is to explore a new mechanism for the formation of strange nuclear systems via capture of hyperons by relatively cold spectator matter produced in semiperipheral collisions. We investigate basic characteristics of the produced hyperspectators and estimate the production probabilities of multistrange systems. Advantages of the proposed mechanisms over an alternative coalescence process are analyzed. We also discuss how such hyperfragments can be detected by taking into account the background of free hyperons. This investigation is important for the development of new experimental methods for producing hypernuclei in peripheral relativistic nucleus-nucleus collisions, which are now underway at GSI and are planned for the future FAIR and NICA facilities.

  15. Proposal for Sustainable Dynamic Lighting in Sport Facilities to Decrease Violence among Spectators

    Directory of Open Access Journals (Sweden)

    Raquel Amorim

    2016-12-01

    Full Text Available Violence among spectators at sports events has become a serious problem, not only for its evident impact on safety, but also from the perspective of environmental, cultural, economic and social sustainability. Although it could be considered a purely social problem, some solutions could come from a smart and efficient design and management of the lighting installations. Thus, the management of sports installations requires deep considerations of lighting technology for three reasons: (1 accurate illumination allows the users to achieve their visual task with comfort and safety; (2 the energy consumption of sports facilities can be decreased with an efficient design of the lighting installation; and (3 the lighting impacts some psychological and physiological aspects such as arousal, stress or relaxation which are directly related to violence. In this work, the recent advances on the matter of light sources and non-visual effects of light are deployed within a new proposal of dynamic Light-emitting diode (LED lighting to decrease violence among spectators. Here, sustainable sports facilities are considered from a global perspective where accurate illumination in each zone (court, bleachers, training rooms and surrounding streets plays an important role in violence avoidance.

  16. Effects due to spectator interaction in deep inelastic processes

    International Nuclear Information System (INIS)

    Smilga, A.V.

    1979-01-01

    The simplest diagrams describing interaction with the spectator in the e - π→e - + hadrons deep inelastic process are considered. The contribution of the final state interaction diagram to the structure function considerable in the Feynman gauge is suppressed under the temporal gauge choice in accordance with the results of the naive parton model. The expressin for the cross section of the process when large quark momentum is transferred to the spectator is derived

  17. Athletic Events and Spectacular Spectators: A Longitudinal Study of Fan Aggression.

    Science.gov (United States)

    Bryan, Clifford; Horton, Robert

    Athletic programs in the public schools and colleges are often justified by assertions that competitive team sports build character and sportsmanship for participants and spectators, and that sports reinforce such school and community ideals as the virtues of competition, patriotism, and the desirability of healthy living. Spectator behavior at…

  18. WEAKLY INTERACTING MASSIVE PARTICLE DARK MATTER AND FIRST STARS: SUPPRESSION OF FRAGMENTATION IN PRIMORDIAL STAR FORMATION

    International Nuclear Information System (INIS)

    Smith, Rowan J.; Glover, Simon C. O.; Klessen, Ralf S.; Iocco, Fabio; Schleicher, Dominik R. G.; Hirano, Shingo; Yoshida, Naoki

    2012-01-01

    We present the first three-dimensional simulations to include the effects of dark matter annihilation feedback during the collapse of primordial minihalos. We begin our simulations from cosmological initial conditions and account for dark matter annihilation in our treatment of the chemical and thermal evolution of the gas. The dark matter is modeled using an analytical density profile that responds to changes in the peak gas density. We find that the gas can collapse to high densities despite the additional energy input from the dark matter. No objects supported purely by dark matter annihilation heating are formed in our simulations. However, we find that dark matter annihilation heating has a large effect on the evolution of the gas following the formation of the first protostar. Previous simulations without dark matter annihilation found that protostellar disks around Population III stars rapidly fragmented, forming multiple protostars that underwent mergers or ejections. When dark matter annihilation is included, however, these disks become stable to radii of 1000 AU or more. In the cases where fragmentation does occur, it is a wide binary that is formed.

  19. Conditions of fragment formation in central and peripheral collisions

    International Nuclear Information System (INIS)

    Mueller, W.F.J.

    1999-01-01

    We report on new measurements of the breakup temperature determined from isotope ratios as well as from state population ratios for the decay of the spectator in Au+Au collisions at 600 and 1000 A MeV and compare them to results for the decay of the participant region at beam energies of 50-200 A MeV. Temperatures deduced from the new isotope thermometer T BeLi exhibit a pronounced rise with increasing excitation energy and are consistent with the previously studied T HeLi . In contrast, temperatures determined from state population ratios show no dependence on excitation energy. An improved calorimetric determination of the excitation energy for the spectator shows a significant increase with increasing bombarding energy which is in contrast to the observed universality of the fragment production. (orig.)

  20. Spectator Consumer Behaviors at the 2012 London Paralympic Games

    Directory of Open Access Journals (Sweden)

    Ridvan Ekmekci

    2013-01-01

    Full Text Available Although the Paralympics are the world’s second largest sporting event after the Olympics and continue to grow in popularity, there is little available research regarding spectators of sport competitions for disabled athletes. The purpose of this study was to profile spectators’ consumer behaviors in order to understand what factors explain spectators’ spending, length of stay, and attendance at the London Paralympic Games. Data was collected in a six-day period from a sample of 504 people present in London at three Paralympic sport facilities during the 2012 Paralympic Games. The results of the regression analyses revealed that nationality, attended contests, group size, having a connection with a Paralympic athlete, length of stay, gender and London Olympics’ spectators were significant determinants of Paralympics spectators’ spending in London. The data also indicated that spending, being from England (or not, gender, and being a friend/relative of a Paralympic athlete significantly affected spectators’ length of stay in London. Additionally, spectators’ attendance at the London Paralympic contests was predicted by spending, the size of the travel group, Beijing Paralympics’ spectators and age.

  1. Resonant Auger electron-photoion coincidence study of the fragmentation dynamics of an acrylonitrile molecule

    Energy Technology Data Exchange (ETDEWEB)

    Kooser, K; Ha, D T; Granroth, S; Itaelae, E; Nommiste, E; Kukk, E [Department of Physics, University of Turku, FIN-20014 Turku (Finland); Partanen, L; Aksela, H, E-mail: kunkoo@utu.f [Department of Physics, University of Oulu, Box 3000, FIN-90014 Oulu (Finland)

    2010-12-14

    Monochromatic synchrotron radiation was used to promote K-shell electrons of nitrogen and carbon from the cyano group (C {identical_to} N) of gaseous acrylonitrile (C{sub 2}H{sub 3}-CN) to the unoccupied antibonding {pi}*{sub C} {sub {identical_to} N} orbital. Photofragmentation of acrylonitrile molecules following selective resonant core excitations of carbon and nitrogen core electrons to the {pi}*{sub C} {sub {identical_to} N} orbital was investigated using the electron-energy-resolved photoelecton-photoion coincidence technique. The fragment ion mass spectra were recorded in coincidence with the resonant Auger electrons, emitted in the decay process of the core-excited states. Singly and triply deuterated samples were used for fragment identification. The results showed the initial core-hole localization to be of minor importance in determining the dissociation pattern of the molecular cation. The participator and spectator Auger transitions produce entirely different fragmentation patterns and the latter indicates that complex nuclear rearrangements take place. It is suggested that the calculated kinetic energy releases are caused by the existence of metastable states, which appear with the opening of the spectator Auger channels.

  2. Energy damping and intermediate velocity fragment emission in peripheral Kr+Au collisions at 43 MeV/u

    International Nuclear Information System (INIS)

    Stuttge, L.; Adloff, J.C.; Bilwes, B.; Bilwes, R.; Cosmo, F.; Glaser, M.; Rudolf, G.; Scheibling, F.

    1991-01-01

    Triple and four-fold coincidences among fragments have been measured in the reaction 197 Au( 84 Kr,X) at 43 MeV/u. All events showing the projectile-like nucleus and fission fragments of the target-like nucleus, and all events with one additional intermediate velocity fragment, were analysed in the frame of a dissipative collision and a participant-spectator model. The mechanism is basically that of a dissipative collision but the emission of the intermediate velocity fragment by the target differs from an equilibrated evaporation. (author) 16 refs., 10 figs

  3. An athlete’s criminal liability towards spectators

    Directory of Open Access Journals (Sweden)

    mohammad nabipour

    2017-10-01

    Full Text Available Abstract:   Basically and according to clause of article 158 of the Islamic penal code, approved in 2013 (sporting activities and accidents resulting from it, if the reason of accidents do not violate the rules related to that sport and these regulation are not in conflict with religious rules there will be no criminal liability for the athlete. As it appears the athlete that will be exempted from any criminal offense when he has not violated the rules, however, if the athletes is offender whether the injured is opponent athlete or one of the spectators, the offending athletes will be liable for the penalty. In other words, what kind of criminal responsibility would be in these cases, if the act committed by him towards the spectator was deliberate (which would warrants retaliation or a psedudo_deliberate error (which would warrants the payment of atonement and also sanction punishment it means that imprisonment 1 to 3 years in case of victim death by the offending athlete according to article 616 in sanction law or vasted error (which would warrants prey for a loss by kinsmam the responsibility of the athlete will be different.But whether the athlete respect to all of the rules he will be completely exempted from the damage that he enters into the spectator or not, is the point of disagreement which this article seeks to ask the question.    

  4. Inclusive breakup of three-fragment weakly bound nuclei

    International Nuclear Information System (INIS)

    Carlson, B.V.; Frederico, T.; Hussein, M.S.

    2017-01-01

    The inclusive breakup of three-fragment projectiles is discussed within a four-body spectator model. Both the elastic breakup and the non-elastic breakup are obtained in a unified framework. Originally developed in the 80's for two-fragment projectiles such as the deuteron, in this paper the theory is successfully generalized to three-fragment projectiles. The expression obtained for the inclusive cross section allows the extraction of the incomplete fusion cross section, and accordingly generalizes the surrogate method to cases such as (t, p) and (t, n) reactions. It is found that two-fragment correlations inside the projectile affect in a conspicuous way the elastic breakup cross section. The inclusive non-elastic breakup cross section is calculated and is found to contain the contribution of a three-body absorption term that is also strongly influenced by the two-fragment correlations. This latter cross section contains the so-called incomplete fusion where more than one compound nuclei are formed. Our theory describes both stable weakly bound three-fragment projectiles and unstable ones such as the Borromean nuclei.

  5. Inclusive breakup of three-fragment weakly bound nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, B.V.; Frederico, T. [Instituto Tecnológico de Aeronáutica, DCTA, 12.228-900 São José dos Campos, SP (Brazil); Hussein, M.S., E-mail: hussein@if.usp.br [Instituto Tecnológico de Aeronáutica, DCTA, 12.228-900 São José dos Campos, SP (Brazil); Instituto de Estudos Avançados, Universidade de São Paulo, C.P. 72012, 05508-970 São Paulo, SP (Brazil); Instituto de Física, Universidade de São Paulo, C.P. 66318, 05314-970 São Paulo, SP (Brazil)

    2017-04-10

    The inclusive breakup of three-fragment projectiles is discussed within a four-body spectator model. Both the elastic breakup and the non-elastic breakup are obtained in a unified framework. Originally developed in the 80's for two-fragment projectiles such as the deuteron, in this paper the theory is successfully generalized to three-fragment projectiles. The expression obtained for the inclusive cross section allows the extraction of the incomplete fusion cross section, and accordingly generalizes the surrogate method to cases such as (t, p) and (t, n) reactions. It is found that two-fragment correlations inside the projectile affect in a conspicuous way the elastic breakup cross section. The inclusive non-elastic breakup cross section is calculated and is found to contain the contribution of a three-body absorption term that is also strongly influenced by the two-fragment correlations. This latter cross section contains the so-called incomplete fusion where more than one compound nuclei are formed. Our theory describes both stable weakly bound three-fragment projectiles and unstable ones such as the Borromean nuclei.

  6. Overserving and Allowed Entry of Obviously Alcohol-Intoxicated Spectators at Sporting Events.

    Science.gov (United States)

    Elgán, Tobias H; Durbeej, Natalie; Holder, Harold D; Gripenberg, Johanna

    2018-02-01

    Alcohol intoxication among spectators at sporting events and related problems, such as violence, are of great concern in many countries around the world. However, knowledge is scarce about whether or not alcohol is served to obviously intoxicated spectators at licensed premises inside and outside the sporting arenas, and if obviously intoxicated spectators are allowed entrance to these events. The objective of this study was therefore to examine the occurrences of overserving at licensed premises inside and outside arenas, and of allowed entry of obviously intoxicated spectators into arenas. An observational study assessing the rate of denied alcohol service and denied entry to arenas of trained professional actors portraying a standardized scene of obvious alcohol intoxication (i.e., pseudo-patrons) was conducted. The scene was developed by an expert panel, and each attempt was monitored by an observer. The settings were 2 arenas hosting matches in the Swedish Premier Football League in the largest city in Sweden and 1 arena in the second largest city, including entrances and licensed premises inside and outside the arenas. The rates of denied alcohol service were 66.9% at licensed premises outside the arenas (n = 151) and 24.9% at premises inside the arenas (n = 237). The rate of denied entry to the arenas (n = 102) was 10.8%. Overserving and allowed entry of obviously alcohol-intoxicated spectators are problematic at sporting events in Sweden and may contribute to high overall intoxication levels among spectators. The differences in server intervention rates indicate that serving staff at licensed premises inside the arenas and entrance staff are not likely to have been trained in responsible beverage service. This result underscores the need for server training among staff at the arenas. Copyright © 2017 by the Research Society on Alcoholism.

  7. On the nuclear fragmentation mechanisms in nuclear collisions at intermediate and high energies

    International Nuclear Information System (INIS)

    Jipa, Al.; Besliu, C.; Felea, D.; Iliescu, B.; Ristea, O.; Ristea, M.; Calin, C.; Horbuniev, A.; Arsene, I.; Esanu, T.; Ochesanu, S.; Caramarcu, C.; Bordeianu, C.; Rosu, I.; Grossu, V.; Zgura, I.S.; Stan, E.; Mitu, C.; Potlog, M.; Cherciu, M.; Stefan, I.

    2004-01-01

    The nuclear fragmentation mechanisms can be discussed taking into account different scales. These scales are related to the fragment sizes. Taking into account the possible different fragmentation mechanisms of the nuclei at the same incident energy an analysis of the experimental results obtained in different experiments performed at the JINR Dubna (Russia), KEK Tsukuba (Japan), GSI Darmstadt (Germany) is done. Results on apparent temperatures, angular distributions, fragment momentum spectra, multiplicities of the intermediate mass fragments are used to analyse the competition between two possible nuclear fragmentation mechanisms, namely: a sudden fragmentation by explosive mechanisms, like shock waves, and a slow fragmentation by the 'fission' of the spectator regions, mainly, because of the interactions with the particles or fragments emitted from the participant region at transverse angles on the incident nucleus, in CMS.Some connections with chaos dynamics and fractal structure of the fragmentation patterns are included. (authors)

  8. Angular correlations and fragmentation in intermediate energy heavy ion collisions

    International Nuclear Information System (INIS)

    Kristiansson, Anders.

    1990-05-01

    Intermediate energy heavy-ion collisions have been studied from 35 A MeV up to 94 A MeV at various accelerators. Angular correlations between light particles and detection of projectile- and target-fragments have been used to investigate the reaction mechanisms in this transition region between low- and high energy. An excess of correlations is observed in the particle-particle elastic scattering plane. This excess increases with particle mass and can be understood in terms of momentum conservation. The fragmentation measurements gives an indication that both energy and momentum transfer to the spectator volumes does occur. (author)

  9. Relativistic nuclear physics with the spectator model

    International Nuclear Information System (INIS)

    Gross, F.

    1988-01-01

    The spectator model, a general approach to the relativistic treatment of nuclear physics problems in which spectators to nuclear interactions are put on their mass-shell, will be defined nd described. The approach grows out of the relativistic treatment of two and three body systems in which one particle is off-shell, and recent numerical results for the NN interaction will be presented. Two meson-exchange models, one with only 4 mesons (π, σ, /rho/, ω) but with a 25% admixture of γ 5 coupling for the pion, and a second with 6 mesons (π, σ, /rho/, ω, δ, and /eta/) but a pure γ 5 γ/sup mu/ pion coupling, are shown to give very good quantitative fits to NN scattering phase shifts below 400 MeV, and also a good description of the /rho/ 40 Cα elastic scattering observables. 19 refs., 6 figs., 1 tab

  10. Multiple spectator condensates from inflation

    Science.gov (United States)

    Hardwick, Robert J.

    2018-05-01

    We investigate the development of spectator (light test) field condensates due to their quantum fluctuations in a de Sitter inflationary background, making use of the stochastic formalism to describe the system. In this context, a condensate refers to the typical field value found after a coarse-graining using the Hubble scale H, which can be essential to seed the initial conditions required by various post-inflationary processes. We study models with multiple coupled spectators and for the first time we demonstrate that new forms of stationary solution exist (distinct from the standard exponential form) when the potential is asymmetric. Furthermore, we find a critical value for the inter-field coupling as a function of the number of fields above which the formation of stationary condensates collapses to H. Considering some simple two-field example potentials, we are also able to derive a lower limit on the coupling, below which the fluctuations are effectively decoupled, and the standard stationary variance formulae for each field separately can be trusted. These results are all numerically verified by a new publicly available python class (nfield) to solve the coupled Langevin equations over a large number of fields, realisations and timescales. Further applications of this new tool are also discussed.

  11. EXPERIENCE-BASED TYPOLOGY OF SPECTATORS AT AN ...

    African Journals Online (AJOL)

    martinette kruger

    experience. Key words: Market segmentation; Cricket spectators; Cricket Sixes tournament; ... to enjoy various sports as a form of entertainment, to grow tourism, to grow sport participation and ..... e. D is ta n ce. Figure 1. THREE CLUSTER SOLUTION: WARD'S METHOD WITH SQUARED ..... positive word-of-mouth referrals.

  12. Spectator Ions ARE Important! A Kinetic Study of the Copper-Aluminum Displacement Reaction

    Science.gov (United States)

    Sobel, Sabrina G.; Cohen, Skyler

    2010-01-01

    Surprisingly, spectator ions are responsible for unexpected kinetics in the biphasic copper(II)-aluminum displacement reaction, with the rate of reaction dependent on the identity of the otherwise ignored spectator ions. Application of a published kinetic analysis developed for a reaction between a rotating Al disk and a Cu(II) ion solution to the…

  13. Affleck-Dine baryogenesis, condensate fragmentation and gravitino dark matter in gauge-mediation with a large messenger mass

    International Nuclear Information System (INIS)

    Doddato, Francesca; McDonald, John

    2011-01-01

    We study the conditions for successful Affleck-Dine baryogenesis and the origin of gravitino dark matter in GMSB models. AD baryogenesis in GMSB models is ruled out by neutron star stability unless Q-balls are unstable and decay before nucleosynthesis. Unstable Q-balls can form if the messenger mass scale is larger than the flat-direction field Φ when the condensate fragments. We provide an example based on AD baryogenesis along a d = 6 flat direction for the case where m 3/2 ≈ 2GeV, as predicted by gravitino dark matter from Q-ball decay. Using a phenomenological GMSB potential which models the Φ dependence of the SUSY breaking terms, we numerically solve for the evolution of Φ and show that the messenger mass can be sufficiently close to the flat-direction field when the condensate fragments. We compute the corresponding reheating temperature and the baryonic charge of the condensate fragments and show that the charge is large enough to produce late-decaying Q-balls which can be the origin of gravitino dark matter

  14. Tagged spectator deep-inelastic scattering off the deuteron as a tool to study neutron structure

    International Nuclear Information System (INIS)

    Cosyn, W.; Sargsian, M.

    2016-01-01

    We give an overview of a model to describe deep-inelastic scattering (DIS) off the deuteron with a spectator proton (e+d → e'+X+p s ), based on the virtual nucleon approximation (VNA). The model accounts for the final-state interactions (FSI) of the DIS debris with the spectator proton. Values of the rescattering cross section are obtained by fits to high-momentum spectator data. By using the so-called 'pole extrapolation' method, free neutron structure functions can be obtained by extrapolating low-momentum spectator proton data to the on-shell neutron pole. We apply this method to the BONuS data set and find a surprising Bjorken x dependence, indicating a possible rise of the neutron to proton structure function ratio at high x. (authors)

  15. Pion absorption in excited nuclear matter

    International Nuclear Information System (INIS)

    Schmidt, H.R.; Albrecht, R.; Bock, R.; Gutbrod, H.H.; Kolb, B.W.; Lund, I.; Awes, T.C.; Baktash, C.; Ferguson, R.L.; Lee, I.Y.; Plasil, F.; Saini, S.; Tincknell, M.; Young, G.R.; Beckmann, P.; Berger, F.; Clewing, G.; Dragon, L.; Glasow, R.; Kampert, K.H.; Peitzmann, T.; Purschke, M.; Santo, R.; Claesson, G.; Eklund, A.; Garpman, S.; Gustafsson, H.A.; Idh, J.; Oskarsson, A.; Otterlund, I.; Persson, S.; Stenlund, E.; Franz, A.; Jacobs, P.; Poskanzer, A.M.; Ritter, H.G.; Kristiansson, P.; Loehner, H.; Obenshain, F.E.; Sorensen, S.P.; Siemiarczuk, T.

    1992-02-01

    The target dependence and azimuthal correlations of protons and plons are investigated for pA reactions at 4.9, 60 and 200 GeV. The experimental observations can be understood qualitatively under the assumption that pions are absorbed in excited target spectator matter. (orig.)

  16. Spectator tagging in quasi-free pn-reactions on deuterium at PROMICE/WASA, CELSIUS

    International Nuclear Information System (INIS)

    Bilger, R.; Brodowski, W.; Calen, H.; Clement, H.; Dunin, V.; Dyring, J.; Ekstroem, C.; Fransson, K.; Greiff, J.; Gustafsson, L.; Haeggstroem, S.; Hoeistad, B.; Johanson, J.; Johansson, A.; Johansson, T.; Khoukaz, A.; Kilian, K.; Koch, I.; Kullander, S.; Kupsc, A.; Marciniewski, P.; Morosov, B.; Neubauer, T.; Oelert, W; Ruber, R.; Shwartz, B.; Stepaniak, J.; Sukhanov, A.; Sukhanov, A.; Sundberg, P.; Turowiecki, A.; Wagner, G.; Wilhelmi, Z.; Wilkin, C.; Zabierowski, J.; Zernov, A.; Zlomanczuk, J.

    2000-01-01

    A set of silicon detectors has been added to the PROMICE/WASA (P/W) experiment at CELSIUS. These detectors have been used for spectator-proton tagging in proton deuteron collisions to investigate proton-neutron reactions at intermediate energies. The performance of the setup has been tested by measuring the pd → dπ o p spectator reaction

  17. On the angular distribution of spectator nucleons in high-energy collisions with deuterium nuclei

    International Nuclear Information System (INIS)

    Bartke, J.

    1975-01-01

    Angular distributions of spectator nucleons in collisions of high-energy particles with deuterium nuclei are discussed in the framework of the impulse model. Comparison with experimental data shows that predictions following from this simple theoretical model are verified by experiment. Some general remarks on the study of angular distributions of spectator nucleons are given. (author)

  18. Examining spectator motivations in Major League Baseball: A Comparison between senior and non-senior consumers

    Directory of Open Access Journals (Sweden)

    Junghwan Park

    2016-10-01

    Full Text Available The purpose of this study was to identify the differences in the motives between senior and non-senior sport consumers who attend sport events and to compare the effect of spectator motivation on sport consumption behaviors between senior and non-senior consumers. Multiple regression analyses were conducted to examine the relationship between motivation factors and sport consumption variables for senior and non- senior spectator groups. The results showed that both senior and non-senior spectators were commonly motivated by the following specific motives of escape, social interaction, physical skill and drama for attending a MLB game.

  19. Social perception and "spectator theories" of other minds

    DEFF Research Database (Denmark)

    Overgaard, Søren; Krueger, Joel William

    2013-01-01

    We resist Schilbach et al.'s characterization of the "social perception" approach to social cognition as a "spectator theory" of other minds. We show how the social perception view acknowledges the crucial role interaction plays in enabling social understanding. We also highlight a dilemma...

  20. Target fragmentation in proton-nucleus and 16O-nucleus reactions at 60 and 200 GeV/nucleon

    International Nuclear Information System (INIS)

    Schmidt, H.R.; Albrecht, R.; Claesson, G.; Bock, R.; Gutbrod, H.H.; Kolb, B.W.; Lund, I.; Siemiarczuk, T.; Awes, T.C.; Baktash, C.; Ferguson, R.L.; Lee, I.Y.; Obenshain, F.E.; Plasil, F.; Sorensen, S.P.; Young, G.R.; Beckmann, P.; Berger, F.; Dragon, L.; Glasow, R.; Kampert, K.H.; Loehner, H.; Peitzmann, T.; Purschke, M.; Santo, R.; Franz, A.; Kristiansson, P.; Poskanzer, A.M.; Ritter, H.G.; Garpman, S.; Gustafsson, H.A.; Oskarsson, A.; Otterlund, I.; Persson, S.; Stenlund, E.

    1988-01-01

    Target remnants with Z 16 O-nucleus reactions at 60 and 200 GeV/nucleon were measured in the angular range from 30 0 to 160 0 (-1.7 16 O-induced reactions (≅ 300 MeV/c) than in proton-induced reactions (≅ 130 MeV/c). The baryon rapidity distributions are roughly in agreement with one-fluid hydrodynamical calculations at 60 GeV/nucleon 16 O+Au but are in disagreement at 200 GeV/nucleon, indicating the higher degree of transparency at the higher bombarding energy. Both, the transverse momenta of target spectators and the entropy produced in the target fragmentation region are compared to those attained in head-on collisions of two heavy nuclei at Bevalac energies. They are found to be comparable or do even exceed the values for the participant matter at beam energies of about 1-2 GeV/nucleon. (orig.)

  1. Target fragmentation in proton-nucleus and 16O-nucleus reactions at 60 and 200 GeV/nucleon

    International Nuclear Information System (INIS)

    Schmidt, H.R.; Albrecht, R.; Claesson, G.; Bock, R.; Gutbrod, H.H.; Kolb, B.W.; Lund, I.; Siemiarczuk, T.; Awes, T.C.; Baktash, C.; Ferguson, R.L.; Lee, I.Y.; Obenshain, F.E.; Plasil, F.; Sorensen, S.P.; Young, G.R.; Beckmann, P.; Berger, F.; Dragon, L.; Glasow, R.; Kampert, K.H.; Loehner, H.; Peitzmann, T.; Purschke, M.; Santo, R.; Franz, A.; Kristiansson, P.; Poskanzer, A.M.; Ritter, H.G.; Garpman, S.; Gustafsson, H.A.; Oskarsson, A.; Otterlund, I.; Persson, S.; Stenlund, E.

    1988-01-01

    Target remnants with Z 16 O-nucleus reactions at 60 and 200 GeV/nucleon were measured in the angular range from 30 0 to 160 0 (-1.7 16 O-induced reactions (= 300 MeV/c) than in proton-induced reactions (= 130 MeV/c). The baryon rapidity distributions are roughly in agreement with one-fluid hydrodynamical calculations at 60 GeV/nucleon 16 O+Au but are in disagreement at 200 GeV/nucleon, indicating the higher degree of transparency at the higher bombarding energy. Both, the transverse momenta of target spectators and the entropy produced in the target fragmentation region are compared to those attained in head-on collisions of two heavy nuclei at Bevalac energies. They are found to be comparable or do even exceed the values for the participant matter at beam energies of about 1-2 GeV/nucleon. (orig.)

  2. Spectator experience management at FIA World Rally Championship events

    Directory of Open Access Journals (Sweden)

    Dr Hans Erik Næss

    2016-10-01

    Full Text Available In light of the Fédération Internationale de l’Automobile’s (FIA call for research into what is needed to make world motorsport championships grow towards 2025, this paper responds by offering a framework for improving spectator experiences at the service parks of the FIA World Rally Championship (WRC events based on five design principles of ‘the experience economy’: 1 theme the experience, 2 harmonise impressions with positive cues, 3 eliminate negative cues, 4 mix in memorabilia and 5 engage the senses. Drawing on ethnographic fieldwork on seven WRC events in the period 2009-15, the result is a comprehensive set of findings that, while tailored to meet the WRC’s challenges, also includes theoretical and methodological insights relevant to other sporting bodies on how to manage spectator experiences to competitive advantage.

  3. Made in Denmark 2014 - Evaluation of Spectator Experience and Tourism Economic Impacts

    DEFF Research Database (Denmark)

    Toft, Henrik; Zahle Østergaard, Mads

    2015-01-01

    This report is a translation of the impact analysis of the golf tournament, Made in Denmark, which was held in August 2014. The content of the report is divided into two sub-parts. The first part is an analysis of the spectator experience and how well the experience of being at this event was ass...... was asssessed by the spectators. The second part is a tourism economic impact analysis which purpose is to analyse, evaluate and assess the economic impact this event had on the local area where it was held....

  4. Spectator electric fields, de Sitter spacetime, and the Schwinger effect

    Science.gov (United States)

    Giovannini, Massimo

    2018-03-01

    During a de Sitter stage of expansion, the spectator fields of different spin are constrained by the critical density bound and by further requirements determined by their specific physical nature. The evolution of spectator electric fields in conformally flat background geometries is occasionally concocted by postulating the existence of ad hoc currents, but this apparently innocuous trick violates the second law of thermodynamics. Such a problem occurs, in particular, for those configurations (customarily employed for the analysis of the Schwinger effect in four-dimensional de Sitter backgrounds) leading to an electric energy density which is practically unaffected by the expansion of the underlying geometry. The obtained results are compared with more mundane situations where Joule heating develops in the early stages of a quasi-de Sitter phase.

  5. Motor Simulation without Motor Expertise: Enhanced Corticospinal Excitability in Visually Experienced Dance Spectators

    Science.gov (United States)

    Jola, Corinne; Abedian-Amiri, Ali; Kuppuswamy, Annapoorna; Pollick, Frank E.; Grosbras, Marie-Hélène

    2012-01-01

    The human “mirror-system” is suggested to play a crucial role in action observation and execution, and is characterized by activity in the premotor and parietal cortices during the passive observation of movements. The previous motor experience of the observer has been shown to enhance the activity in this network. Yet visual experience could also have a determinant influence when watching more complex actions, as in dance performances. Here we tested the impact visual experience has on motor simulation when watching dance, by measuring changes in corticospinal excitability. We also tested the effects of empathic abilities. To fully match the participants' long-term visual experience with the present experimental setting, we used three live solo dance performances: ballet, Indian dance, and non-dance. Participants were either frequent dance spectators of ballet or Indian dance, or “novices” who never watched dance. None of the spectators had been physically trained in these dance styles. Transcranial magnetic stimulation was used to measure corticospinal excitability by means of motor-evoked potentials (MEPs) in both the hand and the arm, because the hand is specifically used in Indian dance and the arm is frequently engaged in ballet dance movements. We observed that frequent ballet spectators showed larger MEP amplitudes in the arm muscles when watching ballet compared to when they watched other performances. We also found that the higher Indian dance spectators scored on the fantasy subscale of the Interpersonal Reactivity Index, the larger their MEPs were in the arms when watching Indian dance. Our results show that even without physical training, corticospinal excitability can be enhanced as a function of either visual experience or the tendency to imaginatively transpose oneself into fictional characters. We suggest that spectators covertly simulate the movements for which they have acquired visual experience, and that empathic abilities heighten

  6. Spectator effects in inclusive decays of beauty hadrons

    CERN Document Server

    Neubert, M

    1997-01-01

    We present a model-independent study of spectator effects, which are responsible for the lifetime differences between beauty hadrons. These effects can be parametrized in terms of hadronic matrix elements of four four-quark operators. For B mesons, the coefficients of the non-factorizable operators turn out to be a factor 10--100 larger than those of the factorizable ones, and so the vacuum insertion approximation cannot be trusted. Theoretically, the deviation of \\tau(B^-)/\\tau(B_d) from unity could be as large as 20\\%, and even the sign of this deviation cannot be predicted at present. In the case of the \\Lambda_b baryon, heavy-quark symmetry is used to reduce the number of independent matrix elements from four to two. In order to explain the large deviation from unity in the experimental result for \\tau(\\Lambda_b)/\\tau(B_d), it is necessary that these baryon matrix elements be much larger than those estimated in quark models. We also study spectator effects in the semi-leptonic branching ratio of B mesons ...

  7. Motivational Factors for Evaluating Sport Spectator and Participant Markets.

    Science.gov (United States)

    McDonald, Mark A.; Milne, George R.; Hong, JinBae

    2002-01-01

    Suggests a motivations framework to organize constructs for evaluating sport consumption. Researchers developed scales to measure motivations for spectating and participant markets, then surveyed 1,611 sports enthusiasts nationwide, profiling sports using motivational constructs. The proposed constructs are shown to have implications for marketing…

  8. Hubble induced mass after inflation in spectator field models

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, Tomohiro [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University, Stanford, CA 94306 (United States); Harigaya, Keisuke, E-mail: tomofuji@stanford.edu, E-mail: keisukeh@icrr.u-tokyo.ac.jp [Department of Physics, University of California, Berkeley, CA 94720 (United States)

    2016-12-01

    Spectator field models such as the curvaton scenario and the modulated reheating are attractive scenarios for the generation of the cosmic curvature perturbation, as the constraints on inflation models are relaxed. In this paper, we discuss the effect of Hubble induced masses on the dynamics of spectator fields after inflation. We pay particular attention to the Hubble induced mass by the kinetic energy of an oscillating inflaton, which is generically unsuppressed but often overlooked. In the curvaton scenario, the Hubble induced mass relaxes the constraint on the property of the inflaton and the curvaton, such as the reheating temperature and the inflation scale. We comment on the implication of our discussion for baryogenesis in the curvaton scenario. In the modulated reheating, the predictions of models e.g. the non-gaussianity can be considerably altered. Furthermore, we propose a new model of the modulated reheating utilizing the Hubble induced mass which realizes a wide range of the local non-gaussianity parameter.

  9. Identification and tracking of low energy spectator protons

    Energy Technology Data Exchange (ETDEWEB)

    Mussgiller, A.

    2007-07-20

    The present theses discusses the development, technical design and realization as well as the read-out electronics of a detection system for the identification and tracking of low energy spectator protons. With the knowledge of the four-momentum of such spectator protons it will be possible to use deuterium as an effective neutron target. Previous measurements with an early version of the detection system have already shown that this method works quite well to investigate for instance the {omega} or {eta}-meson production in proton-neutron collisions. Moreover, after the completion and installation of the polarized internal target (PIT) at ANKE, it will be even possible to engage in that field with double polarized experiments. To increase the luminosity the polarized target is equipped with an extended target cell. The described detection-system will provide the vertex reconstruction for this extended interaction region. In addition, it will act as an independent beam polarimeter at ANKE. The detection system consists of three layers of double-sided silicon strip detectors which are arranged in a telescope structure and placed inside the accelerator vacuum as close as 2 cm to the interaction region. The modular design of the electronics and the support structures for the detectors allows one to exchange detectors and electronics in a maximum flexible way. In a minimum configuration the telescope is equipped with two detectors, a thin ({approx} 69 {mu}m) double-sided Silicon strip detector as a first layer and a very thick ({>=} 5 mm) double-sided micro-structured Lithium-drifted Silicon detector as a second layer. With this arrangement it is possible to track and identify protons in a kinetic energy range from 2.5 MeV to 25 MeV. For deuterons this range for such a telescope configuration is from 4 MeV to 34 MeV. The performance concerning the energy determination and tracking is shown based on data taken during a beam-time in November of 2003. With the existing

  10. Identification and tracking of low energy spectator protons

    International Nuclear Information System (INIS)

    Mussgiller, A.

    2007-01-01

    The present theses discusses the development, technical design and realization as well as the read-out electronics of a detection system for the identification and tracking of low energy spectator protons. With the knowledge of the four-momentum of such spectator protons it will be possible to use deuterium as an effective neutron target. Previous measurements with an early version of the detection system have already shown that this method works quite well to investigate for instance the ω or η-meson production in proton-neutron collisions. Moreover, after the completion and installation of the polarized internal target (PIT) at ANKE, it will be even possible to engage in that field with double polarized experiments. To increase the luminosity the polarized target is equipped with an extended target cell. The described detection-system will provide the vertex reconstruction for this extended interaction region. In addition, it will act as an independent beam polarimeter at ANKE. The detection system consists of three layers of double-sided silicon strip detectors which are arranged in a telescope structure and placed inside the accelerator vacuum as close as 2 cm to the interaction region. The modular design of the electronics and the support structures for the detectors allows one to exchange detectors and electronics in a maximum flexible way. In a minimum configuration the telescope is equipped with two detectors, a thin (∼ 69 μm) double-sided Silicon strip detector as a first layer and a very thick (≥ 5 mm) double-sided micro-structured Lithium-drifted Silicon detector as a second layer. With this arrangement it is possible to track and identify protons in a kinetic energy range from 2.5 MeV to 25 MeV. For deuterons this range for such a telescope configuration is from 4 MeV to 34 MeV. The performance concerning the energy determination and tracking is shown based on data taken during a beam-time in November of 2003. With the existing setup an energy

  11. See you at the match: Motivation for sport consumption and intrinsic psychological reward of premier football league spectators in South Africa

    Directory of Open Access Journals (Sweden)

    Frederick W. Stander

    2016-04-01

    Full Text Available Orientation: Local football contributes significantly to the social- and economic welfare of South Africa through its spectators. Understanding the motives and experiences of football spectators could provide opportunities for capitalising on football as revenue stream feeding the South African economy. Research purpose: To investigate how motives for sport consumption predict intrinsic psychological reward of South African premier league football spectators. Motivation for the study: Sport - particularly football - is an untapped resource for stimulating economic development and growth through its consumers. Spectators, who often experience their investment in the sport as deeply rewarding and meaningful, should participate more frequently in purchasing products or services associated with the sport. Through understanding the motives for sport consumption of South African premier league football spectators and the impact of these motives on intrinsic psychological reward experiences, football clubs are able to provide a targeted experience or service to spectators in order to further stimulate economic growth. Research design, approach and method: A census sample of 806 football spectators attending various matches at a football stadium in Soweto was drawn. A cross-sectional research design was implemented. This research was exploratory and descriptive. Structural equation modelling was implemented to assess the factor structures of the constructs, to confirm composite reliability of the measures and to assess the structural paths between the variables. Main findings: A predictive model for intrinsic psychological rewards (life satisfaction and meaning through the motivation for sport consumption (individual – and game related factors was confirmed. It was further established that motivation for sport consumption is significantly positively a related to and b associated with the experience of intrinsic psychological reward by South African

  12. Fragmentation into strange particles in high energy νp, νn, anti νp and anti νn interactions

    International Nuclear Information System (INIS)

    Allasia, D.; Cirio, R.; Gamba, D.; Ramello, L.; Riccati, L.; Romero, A.; Rustichelli, S.; Angelini, C.; Baldini, A.; Bertanza, L.; Casali, R.; Fantechi, R.; Flaminio, V.; Pazzi, R.; Bloch, M.; Bolognese, T.; Borg, A.; Faccini-Turluer, M.L.; Lippi, I.; Louedec, C.; Vignaud, D.; Capiluppi, P.; Derkaoui, J.; Giacomelli, G.; Mandrioli, G.; Margiotta, A.; Rossi, A.M.; Serra-Lugaresi, P.; Frodesen, A.G.; Jongejans, B.; Tenner, A.G.; Apeldoorn, G. van; Dam, P. van; Visser, C.; Wigmans, R.

    1985-01-01

    The fragmentation of the hardronic system into Λ, Σ(1385), K 0 and Ksup(*)(892) in deep-inelastic charged-current interactions of high energy neutrinos and antineutrinos with proton and neutron is analyzed. The results obtained for the production of these particles from the various initial states are compared with each other and with the predictions of the Lund fragmentation model. This comparison shows that a spectator diquark does not fragment as a whole in a fraction of the interactions. The role of the sea quarks in the baryon formation process is underlined. Strange vector and pseudoscalar mesons are likely to be produced at similar rates. (orig.)

  13. Experience-based typology of spectators at an international cricket ...

    African Journals Online (AJOL)

    This innovative research on managing and marketing team sport events was completed for the first time at an international Cricket Sixes tournament held in South Africa (SA). A visitor survey was conducted at SuperSport Park in Centurion during the Global Softech Sixes Tournament in 2014. Finally, spectators, who were ...

  14. Performance of centrality determination in heavy-ion collisions with CBM experiment

    Energy Technology Data Exchange (ETDEWEB)

    Klochkov, Viktor; Selyuzhenkov, Ilya [GSI, Darmstadt (Germany); Collaboration: CBM-Collaboration

    2016-07-01

    The goal of the CBM experiment at FAIR is to investigate the properties of compressed baryonic matter. The measurement of physics observables in heavy-ion collisions requires information about event geometry. A magnitude of the impact parameter, which is among the most important parameters to describe collision geometry, cannot be measured directly in experiment. One can estimate it by measuring produced particle's multiplicities or energy of the spectator fragments. Typically, the collisions are divided into centrality classes which corresponds to the ranges of impact parameter with e.g. centrality class 0-5% corresponds to most central events, and 95-100% to the most peripheral collisions. Sensitivity to the range of impact parameters with the Silicon Tracking System (STS) and Projectile Spectator Detector (PSD) to select centrality classes in the CBM experiment will be presented. The STS is measuring the multiplicity of the particles produced in the nuclei overlap zone and different areas of the PSD are sensitive to both spectator fragments and produced particles. Supported by the GSI Helmholtzzentrum fuer Schwerionenforschung.

  15. Similarity of multi-fragmentation of residual nucleus created in nucleus-nucleus interactions at high energies

    International Nuclear Information System (INIS)

    Abdel-Hafiez, A.; Chernyavski, M.M.; Orlova, G.I.; Gulamov, K.G.; Navotny, V.SH.; Uzhinskii, V.V.

    2000-01-01

    Experimental data on multi-fragmentation of residual krypton nuclei created in the interactions of the krypton nuclei with photoemulsion nuclei ut energy of 0.9 GeV per nucleon are presented in a comparison with the analogous data on fragmentation of gold residual nuclei at the energy of 10.7 GeV/nucleon. It is shown for the first time that there are two regimes of nuclear multifragmentation: the former is when less than one-half of nucleons of projectile nucleus are knocked out, the later is when more than one-half of nucleons are knocked out. Residual nuclei with closed masses created at different reactions are fragmenting practically simultaneously when more than one-half of nucleons of original nuclei are knocked out. The evidence of existence of a radial flow of the spectator fragment at the decay of residual krypton nuclei is found

  16. CALCULATION OF FRAGMENTATION FUNCTIONS IN TWO-HADRON SEMI-INCLUSIVE PROCESSES

    International Nuclear Information System (INIS)

    BIANCONI, A.; BOFFI, S.; BOER, D.; JAKOB, R.; RADICI, M.

    2001-01-01

    We investigate the properties of interference fragmentation functions arising from the emission of two leading hadrons inside the same jet for inclusive lepton-nucleon deep inelastic scattering. Using an extended spectator model for the mechanism of the hadronization, we give a complete calculation and numerical estimates for the examples of a proton-pion pair produced with invariant mass on the Roper resonance, and of two pions produced with invariant mass close to the ρ mass. We discuss azimuthal angular dependence of the leading order cross section to point up favourable conditions for extracting transversity from experimental data

  17. Alcohol intoxication at Swedish football matches: A study using biological sampling to assess blood alcohol concentration levels among spectators.

    Directory of Open Access Journals (Sweden)

    Natalie Durbeej

    Full Text Available Alcohol use and alcohol-related problems, including accidents, vandalism and violence, at sporting events are of increased concern in Sweden and other countries. The relationship between alcohol use and violence has been established and can be explained by the level of intoxication. Given the occurrence of alcohol use and alcohol-related problems at sporting events, research has assessed intoxication levels measured through biological sampling among spectators. This cross-sectional study aimed to assess the level of alcohol intoxication among spectators at football matches in the Swedish Premier Football League. Spectators were randomly selected and invited to participate in the study. Alcohol intoxication was measured with a breath analyser for Blood Alcohol Concentration levels, and data on gender, age, and recent alcohol use were gathered through a face-to-face interview. Blood Alcohol Concentration samples from 4420 spectators were collected. Almost half (46.8% had a positive Blood Alcohol Concentration level, with a mean value of 0.063%, while 8.9% had a Blood Alcohol Concentration level ≥ 0.1%, with a mean value of 0.135%. Factors that predicted a higher Blood Alcohol Concentration level included male gender (p = 0.005, lower age (p < 0.001, attending a local derby (p < 0.001, alcohol use prior to having entered the arena (p < 0.001, attending a weekend match (p < 0.001, and being a spectator at supporter sections (p < 0.001. About half of all spectators at football matches in the Swedish Premier Football League drink alcohol in conjunction with the match. Approximately one tenth have a high level of alcohol intoxication.

  18. Understanding the drivers on medical workloads: an analysis of spectators at the Australian Football League.

    Science.gov (United States)

    Zeitz, Kathryn; Haghighi, Pari Delir; Burstein, Frada; Williams, Jeffrey

    2013-06-01

    The present study was designed to further understand the psychosocial drivers of crowds impacting on the demand for healthcare. This involved analysing different spectator crowds for medical usage at mass gatherings; more specifically, did different football team spectators (of the Australian Football League) generate different medical usage rates. In total, 317 games were analysed from 10 venues over 2 years. Data were analysed by the ANOVA and Pearson correlation tests. RESULTS; Spectators who supported different football teams generated statistically significant differences in patient presentation rates (PPR) (F15, 618=1.998, P=0.014). The present study confirmed previous findings that there is a positive correlation between the crowd size and PPR at mass gatherings but found a negative correlation between density and PPR (r = -0.206, n=317, Pemergency medical care. In measuring demand for emergency medical services there is a need to develop a more sophisticated understanding of a variety of drivers in addition to traditional metrics such as temperature, crowd size and other physical elements. In this study we saw that spectators who supported different football teams generated statistically significant differences in PPR. What is known about this topic? Understanding the drivers of emergency medical care is most important in the mass gathering setting. There has been minimal analysis of psychological 'crowd' variables. What does this paper add? This study explores the psychosocial impact of supporting a different team on the PPR of spectators at Australian Football League matches. The value of collecting and analysing these types of data sets is to support more balanced planning, better decision support and knowledge management, and more effective emergency medical demand management. What are the implications for practitioners? This information further expands the body of evidence being created to understand the drivers of emergency medical demand and usage

  19. Spectators' perceptions of official sponsors in the FIFA 2010 World ...

    African Journals Online (AJOL)

    Sponsorship evolved from a small-scale activity to a major industry world-wide both in terms of money spent and adoption levels by companies. In South Africa, millions of rands are spent on sponsorship every year and on sport sponsorship in particular. The purpose of the study was to determine spectators' perceptions of ...

  20. Quark-diquark fragmentation in 'high mass' diffraction dissociation in proton-proton collisions at 360 GeV/c

    International Nuclear Information System (INIS)

    Asai, Makoto

    1986-01-01

    Using the European Hybrid spectrometer (EHS) system, we have investigated the properties of the four-prong 'high mass' diffraction dissociation process in the exclusive processes pp → pX, where X represents pπ + π - nπ 0 (n = 0, 1, 2). We present experimental evidences that Pomeron couples with a single valence quark in the incident proton and that the other two valence quarks in the proton behaves as the spectator diquark. We also show that most of the baryons are produced from the spectator diquark system in these processes. The p t suppression is also shown in the Gottfried-Jackson frame, the frame in which the excited system composed of Pomeron and the incident proton is at rest. Characteristic features in the hadronization of this process are very much similar to those of quark-diquark fragmentation in lepton-hardron deep inelastic scattering. (author)

  1. Mathematical Practice as Sculpture of Utopia: Models, Ignorance, and the Emancipated Spectator

    Science.gov (United States)

    Appelbaum, Peter

    2012-01-01

    This article uses Ranciere's notion of the ignorant schoolmaster and McElheny's differentiation of artist's models from those of the architect and scientist to propose the reconceptualization of mathematics education as the support of emancipated spectators and sculptors of utopia.

  2. Hume's Spectator Theory%观察者理论与休谟的伦理思想

    Institute of Scientific and Technical Information of China (English)

    胡军方

    2011-01-01

    Spectator theory is an important part in Hurn(s ethics. Along with the sympathy principle and the three prin ciples of imagination, the spectator theory is used in moral evaluation, moral distinction, and the construction of Hume's ethics. This reflects the subjective and empirical character of his ethics. Spectator theory has caused many ethical problems of continued controversies. Thus, understanding the spectator theory is a key to Hume's ethics.%观察者理论是休谟伦理学的一个重要内容。在休谟伦理学中,观察者理论和同情原则、联想三大原则一道被运用于道德评价、道德区分和其伦理学说的构建,这体现了休谟伦理学的主观性、经验性等特征。休谟的观察者理论带来了许多伦理学上的问题,引起了现当代伦理学对该理论的不断争论。领会观察者理论是理解休谟伦理学的一把钥匙。

  3. A comprehensive treatment of electromagnetic interactions and the three-body spectator equations

    Energy Technology Data Exchange (ETDEWEB)

    Jiri Adam; Jay Van Orden

    2004-10-01

    We present a general derivation the three-body spectator (Gross) equations and the corresponding electromagnetic currents. As in previous paper on two-body systems, the wave equations and currents are derived from those for Bethe-Salpeter equation with the help of algebraic method using a concise matrix notation. The three-body interactions and currents introduced by the transition to the spectator approach are isolated and the matrix elements of the e.m. current are presented in detail for system of three indistinguishable particles, namely for elastic scattering and for two and three body break-up. The general expressions are reduced to the one-boson-exchange approximation to make contact with previous work. The method is general in that it does not rely on introduction of the electromagnetic interaction with the help of the minimal replacement. It would therefore work also for other external fields.

  4. Spin polarization of 34Al fragments produced by nucleon pickup at intermediate energies

    International Nuclear Information System (INIS)

    Turzo, K.; Himpe, P.; Borremans, D.; Mallion, S.; Neyens, G.; Vermeulen, N.; Yordanov, D.; Balabanski, D.L.; Belier, G.; Daugas, J.M.; Georgiev, G.; Oliveira de Santos, F.; Matea, I.; Stodel, Ch.; Penionzhkevich, Yu. E.

    2006-01-01

    The polarization of 34 Al fragments, produced by single neutron pickup from a 9 Be target by a 36 S projectile at 77.5 MeV/nucleon, have been observed at GANIL via the detection of resonantly destroyed β-asymmetry. The reaction-induced polarization is deduced using a tentative spin/parity assignment for the 34 Al ground state. A positive polarization was measured near the peak of the 34 Al yield curve. A kinematical model based on the spectator-participant model for projectile fragmentation reactions has been extended in order to take into account the features of pickup reactions, i.e., the picked-up nucleon having an average momentum equal to the Fermi momentum and aligned along the incident beam direction. The trend-line in the observed spin-orientation is very well reproduced by this model

  5. From Spectator to User, From Viewer to (Act)or

    OpenAIRE

    Mitakou, E. N.; Fanou, P.; Zamani, Efpraxia D.

    2013-01-01

    Stephen Hawking, when introducing Krauss’ ‘The Physics of Star Trek’, wrote that “[s]cience fiction (…) is not only good fun but it also serves a serious purpose, that of expanding the human imagination.” In this paper, following a retrospective juxtaposition of the two last centuries’ filmic production, we show how imaginary worlds have become conventional and familiar, while viewers have transformed from mere spectators to users of intelligent technologies. We also exhibit...

  6. On the nuclear fragmentation mechanisms in nuclear collisions at intermediate and high energies

    International Nuclear Information System (INIS)

    Jipa, Al; Besliu, C.; Felea, D.

    2004-01-01

    The nuclear fragmentation mechanisms can be discussed by taking into account different scales related to the fragment sizes. Considering two fragmentation mechanisms of the nuclei at the same incident energy an analysis of the experimental results obtained was done. Goldhaber formula was improved by analyzing the discrepancies between data and theories concerning the projectile fragmentation. We implied that the projectile fragmentation process would be governed by the distribution of nucleon momenta in the projectile after the collision occurred. We used in our analysis protons from the 4 He + 7 Li at 4.5 GeV/c per nucleon incident momentum, as well as from 40 Ar + 12 C at 213 AMeV bombarding energy. We proved that in order to proceed in analyzing the projectile fragmentation process at intermediate and high energies one has to consider the dependence σ 0 on the apparent temperature of projectile nucleus after the collision took place. The generalized Bertsch correction for light projectile nuclei and fragments was used and the number of spatial correlations between identical nucleons having anticorrelated momenta was found. Thus we found apparent temperature values close to the separation energies of the considered fragments per number of fragments. The temperatures associated to kinetic energy spectra of the projectile fragments were calculated following two methods. The results from Bauer's method were compared with those obtained by fitting the kinetic energy distributions of the projectile fragments in the rest frame of the projectile with a Maxwellian curve. We also accomplished the comparison of the experimental results with similar events simulated with RQMD 2.4. All the results obtained suggested two nuclear fragmentation mechanisms: a sudden fragmentation by explosive mechanisms, like shock waves and a slow fragmentation by the 'fission' of the spectator regions, mainly because of the interactions with the particles or fragments emitted from the

  7. Large fragment production calculations in relativistic heavy-ion reactions

    International Nuclear Information System (INIS)

    Seixas de Oliveira, L.F.

    1978-12-01

    The abrasion-ablation model is briefly described and then used to calculate cross sections for production of large fragments resulting from target or projectile fragmentation in high-energy heavy-ion collisions. The number of nucleons removed from the colliding nuclei in the abrasion stage and the excitation energy of the remaining fragments (primary products) are calculated with the geometrical picture of two different models: the fireball and the firestreak models. The charge-to-mass dispersion of the primary products is calculated using either a model which assumes no correlations between proton and neutron positions inside the nucleus (hypergeometric distribution) or a model based upon the zero-point oscillations of the giant dipole resonance (NUC-GDR). Standard Weisskopf--Ewing statistical evaporation calculations are used to calculate final product distributions. Results of the pure abrasion-ablation model are compared with a variety of experimental data. The comparisons show the insufficiency of the extra-surface energy term used in the abrasion calculations. A frictional spectator interaction (FSI) is introduced which increases the average excitation energy of the primary products, and improves the results considerably in most cases. Agreements and discrepancies of the results calculated with the different theoretical assumptions and the experimental data are studied. Of particular relevance is the possibility of observing nuclear ground-state correlations.Results of the recently completed experiment of fragmentation of 213 Mev/A 40 Ar projectiles are studied and shown not to be capable of answering that question unambiguously. But predictions for the upcoming 48 Ca fragmentation experiment clearly show the possibility of observing correlation effects. 78 references

  8. "Some like it hot": spectators who score high on the personality trait openness enjoy the excitement of hearing dancers breathing without music.

    Science.gov (United States)

    Jola, Corinne; Pollick, Frank E; Calvo-Merino, Beatriz

    2014-01-01

    Music is an integral part of dance. Over the last 10 years, however, dance stimuli (without music) have been repeatedly used to study action observation processes, increasing our understanding of the influence of observer's physical abilities on action perception. Moreover, beyond trained skills and empathy traits, very little has been investigated on how other observer or spectators' properties modulate action observation and action preference. Since strong correlations have been shown between music and personality traits, here we aim to investigate how personality traits shape the appreciation of dance when this is presented with three different music/sounds. Therefore, we investigated the relationship between personality traits and the subjective esthetic experience of 52 spectators watching a 24 min lasting contemporary dance performance projected on a big screen containing three movement phrases performed to three different sound scores: classical music (i.e., Bach), an electronic sound-score, and a section without music but where the breathing of the performers was audible. We found that first, spectators rated the experience of watching dance without music significantly different from with music. Second, we found that the higher spectators scored on the Big Five personality factor openness, the more they liked the no-music section. Third, spectators' physical experience with dance was not linked to their appreciation but was significantly related to high average extravert scores. For the first time, we showed that spectators' reported entrainment to watching dance movements without music is strongly related to their personality and thus may need to be considered when using dance as a means to investigate action observation processes and esthetic preferences.

  9. The relationship between visitor spending and repeat visits: An analysis of spectators at the Old Mutual Two Oceans Marathon

    Directory of Open Access Journals (Sweden)

    M. Kruger

    2012-12-01

    Full Text Available Purpose: The purpose of this research is to determine the relationship between visitor spending patterns, and previous and planned return visits as well as demographic and trip characteristics of supporters to the Old Mutual Two Oceans Marathon held annually in Cape Town. Problem investigated: Spectator sport is a significant segment of the tourism industry which also has a considerable economic impact on host communities. For this reason, communities and destinations have recognised and attempt to capitalise on hosting large sporting events. In this regard visitor spending is crucial since information concerning the latter can provide sport event organisers to focus their marketing efforts to attract optimal economic benefits. In addition, the relationship of previous visits to a sport event and intended re-visits to visitor spending has received increasing attention since it is believed that repeat visitation is associated with higher levels of expenditure. However limited attention is currently being paid to the relationship between spectator spending patterns and previous and planned return visits in a South African sport spectator context even though the latter has a direct impact on the future sustainability of an event. Methodology: A supporter survey was done for the first time in 2010 (30 March - 2 April 2010 at the event and 430 questionnaires were completed. Factor analysis and regression analysis are used to analyse the data and to identify the relationship between repeat visits and visitor spending patterns. Findings: Results from this study shows that it is predominantly socio-demographic variables that influence travel behaviour. The significant socio-demographic determinants that influence spending per person are gender, language and province of origin while the only behavioural determinant was group size. The results also revealed that there is no significant relationship between spectator spending, repeat attendance and

  10. Hard spectator interactions in B → ππ at order α2s

    International Nuclear Information System (INIS)

    Pilipp, V.

    2007-01-01

    In the present thesis I discuss the hard spectator interaction amplitude in B → ππ at NLO i.e. at O(α 2 s ). This special part of the amplitude, whose LO starts at O(α s ), is defined in the framework of QCD factorization. QCD factorization allows to separate the short- and the long-distance physics in leading power in an expansion in Λ QCD /m b , where the short-distance physics can be calculated in a perturbative expansion in α s . Compared to other parts of the amplitude hard spectator interactions are formally enhanced by the hard collinear scale √(Λ QCD m b ), which occurs next to the mb-scale and leads to an enhancement of α s . From a technical point of view the main challenges of this calculation are due to the fact that we have to deal with Feynman integrals that come with up to five external legs and with three independent ratios of scales. These Feynman integrals have to be expanded in powers of Δ QCD /m b . I discuss integration by parts identities to reduce the number of master integrals and differential equations techniques to get their power expansions. A concrete implementation of integration by parts identities in a computer algebra system is given in the appendix. Finally I discuss numerical issues like scale dependence of the amplitudes and branching ratios. It turns out that the NLO contributions of the hard spectator interactions are important but small enough for perturbation theory to be valid. (orig.)

  11. Electron-deuteron deep-inelastic scattering with spectator nucleon tagging and final-state interactions at intermediate x

    Science.gov (United States)

    Strikman, M.; Weiss, C.

    2018-03-01

    We consider electron-deuteron deep-inelastic scattering (DIS) with detection of a proton in the nuclear fragmentation region ("spectator tagging") as a method for extracting the free neutron structure functions and studying their nuclear modifications. Such measurements could be performed at a future electron-ion collider (EIC) with suitable forward detectors. The measured proton recoil momentum (≲100 MeV in the deuteron rest frame) specifies the deuteron configuration during the high-energy process and permits a controlled theoretical treatment of nuclear effects. Nuclear and nucleonic structure are separated using methods of light-front quantum mechanics. The impulse approximation to the tagged DIS cross section contains the free neutron pole, which can be reached by on-shell extrapolation in the recoil momentum. Final-state interactions (FSIs) distort the recoil momentum distribution away from the pole. In the intermediate-x region 0.1 rest frame momenta ≲1 GeV , target fragmentation region). We construct a schematic model describing this effect, using final-state hadron distributions measured in nucleon DIS experiments and low-energy hadron scattering amplitudes. We investigate the magnitude of FSIs, their dependence on the recoil momentum (angular dependence, forward/backward regions), their analytic properties, and their effect on the on-shell extrapolation. We comment on the prospects for neutron structure extraction in tagged DIS with an EIC. We discuss possible extensions of the FSI model to other kinematic regions (large/small x ). In tagged DIS at x ≪0.1 FSIs resulting from diffractive scattering on the nucleons become important and require separate treatment.

  12. Simulation of a relativistic heavy ions beam transport in the matter: contribution of the fragmentation process and biological implications

    International Nuclear Information System (INIS)

    Ibnouzahir, M.

    1995-03-01

    The study of relativistic heavy ion collisions permit an approach of the properties of dense and not hadronic matter, and an analysis of the reaction mechanisms. Such studies are also interesting on the biological point of view, since there exist now well defined projects concerning the radiotherapy with high LET particles as neutrons, protons, heavy ions. It is thus necessary to have a good understanding of the processes which occur in the propagation of a relativistic heavy ion beam (E≥ 100 A.MeV) in matter. We have elaborated a three dimensional transport code, using a Monte Carlo method, in order to describe the propagation of Ne and Ar ions in water. Violent nuclear collisions giving fragmentation process have been taken into account by use of the FREESCO program. We have tested the validity of our transport model and we show an important change of the energy deposition at the vicinity of the Bragg peak; such a distortion, due mainly to fragmentation reactions, is of a great interest for biological applications. (author)

  13. Spectator's trust as an indicator of film authorship: Is Vinterberg a film auteur?

    NARCIS (Netherlands)

    van der Pol, G.

    2015-01-01

    In this article, the Trust Model is presented as a new theory to tackle the old film theoretical problem of distinguishing film directors from film auteurs. The model proposes that in certain films, the spectator becomes problematically engaged to the fiction and to certain characters. During the

  14. Pion production and fragmentation of nuclei in high energy nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Oskarsson, A.

    1983-01-01

    In collisions between nuclei at high energies one can study the behaviour of nuclear matter under extreme conditions, regarding nuclear density and temperature. The Bevalac and the CERN SC beams have been used and nuclear emulsion and scintillation telescopes have measured the reaction products. Collisions at 50A-200A MeV and at 2A GeV have been investigated. Proton spectra from 12 C induced reactions at 85A MeV have been recorded for different targets. Energetic protons at large angles can be assumed to be emitted from a source moving with half the beam velocity and a temperature between 13 and 17 MeV, depending on the target. In collisions between nuclei, pions can be produced below 290A MeV due to the internal Fermi motion of the nucleons. Subthreshold pion production has been studied for 12 C induced reactions at 85A and 75A Mev. The cross-sections are consistent with a quasi-free nucleon-nucleon scattering picture, involving Fermi motion, Pauli blocking and pion reabsorption. 16 C induced reactions in emulsion have been studied at 75A, 175A and 2000A MeV. It is shown that the excitation of the parts of the nuclei which are not overlapping (the spectators) increases with the beam energy. The 16 O projectile frequently breaks up into multiple He fragments. These events are associated with large impact parameters. Central collisions with Ag, Br target at 50A-110A MeV have been analysed separately. It is shown that the momentum transfer to the target nucleus is limited to a value considerably lower than the full momentum transfer in a fusion reactions. Events are observed where there are numerous fragments with 3< Z<8. These multifragmentation events cannot be understood in a thermal approach. (author)

  15. Motivation and satisfaction of participants and spectators attending mass sport events

    OpenAIRE

    Cloes, Marc; Emond, Catherine; Ledent, Maryse; Piéron, Maurice

    2000-01-01

    Considering their sociocultural and economic impact, sport events represent a pertinent centre of interest for sport management research. Considering their frequent occurrence and importance to the survival of many associations such as sport clubs, schools, youth or neighbourhood committees, mass sport events could receive more attention than they actually do. In this paper attention was focused on participants and spectators attending the following five mass sport events organised in Walloni...

  16. About dynamic model of limiting fragmentation of heavy nuclei

    International Nuclear Information System (INIS)

    Kuchin, I.A.

    2001-01-01

    production (mainly of mesons) and 'knock out' of fragments under the scheme of the internuclear cascade due to inclusion of nuclear forces on small distances happens. (An one body intermediate state). The principal result of this stage - fast growth of n-dimensionality of a phase space of the process. On a final stage the free dispersion of particles, jets and fragments is observed and formed a tree body final state: spectators-1, participants and spectators-2. The process is obtaining features of a classical character as a result offending to zero of an effective M.Planck's constant ℎ→0, and operation of the laws of propagation of an excitation energy in dissipative mediums. (A realization of S -, LS - and HS - regimes according to A. Samarskiy et al.) General conclusion - the phenomenon of the massive nuclei limiting fragmentation during their high-energy interaction can be considered as an actual example of a passage of quantum chaos to classical one due to growth of a phase space N-regularity of the process under consideration, i.e. as the actual prototype of dynamic evolution of a generic type systems in direction from quantum chaos state to classical one mathematically researched by M. Robnik and others

  17. Fragment library design: using cheminformatics and expert chemists to fill gaps in existing fragment libraries.

    Science.gov (United States)

    Kutchukian, Peter S; So, Sung-Sau; Fischer, Christian; Waller, Chris L

    2015-01-01

    Fragment based screening (FBS) has emerged as a mainstream lead discovery strategy in academia, biotechnology start-ups, and large pharma. As a prerequisite of FBS, a structurally diverse library of fragments is desirable in order to identify chemical matter that will interact with the range of diverse target classes that are prosecuted in contemporary screening campaigns. In addition, it is also desirable to offer synthetically amenable starting points to increase the probability of a successful fragment evolution through medicinal chemistry. Herein we describe a method to identify biologically relevant chemical substructures that are missing from an existing fragment library (chemical gaps), and organize these chemical gaps hierarchically so that medicinal chemists can efficiently navigate the prioritized chemical space and subsequently select purchasable fragments for inclusion in an enhanced fragment library.

  18. Mobile Mapping of Sporting Event Spectators Using Bluetooth Sensors: Tour of Flanders 2011

    Directory of Open Access Journals (Sweden)

    Frederik van Bossche

    2012-10-01

    Full Text Available Accurate spatiotemporal information on crowds is a necessity for a better management in general and for the mitigation of potential security risks. The large numbers of individuals involved and their mobility, however, make generation of this information non-trivial. This paper proposes a novel methodology to estimate and map crowd sizes using mobile Bluetooth sensors and examines to what extent this methodology represents a valuable alternative to existing traditional crowd density estimation methods. The proposed methodology is applied in a unique case study that uses Bluetooth technology for the mobile mapping of spectators of the Tour of Flanders 2011 road cycling race. The locations of nearly 16,000 cell phones of spectators along the race course were registered and detailed views of the spatiotemporal distribution of the crowd were generated. Comparison with visual head counts from camera footage delivered a detection ratio of 13.0 ± 2.3%, making it possible to estimate the crowd size. To our knowledge, this is the first study that uses mobile Bluetooth sensors to count and map a crowd over space and time.

  19. Dynamics of fragments and associated phenomena in heavy-ion collisions using a modified secondary algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Rohit [Department of Physics, Panjab University, Chandigarh-160014 (India)

    2016-05-06

    We discuss the stability of fragments identified by secondary algorithms used to construct fragments within quantum molecular dynamics model. For this purpose we employ three different algorithms for fragment identification. 1) The conventional minimum spanning tree (MST) method based on the spatial correlations, 2) an improved version of MST with additional binding energy constraints of cold nuclear matter, 3) and that of hot matter. We find significant role of thermal binding energies over cold matter binding energies. Significant role is observed for fragment multiplicities and stopping of fragments. Whereas insignificant effect is observed on fragment’s flow.

  20. Spectator interactions in soft-collinear effective theory

    International Nuclear Information System (INIS)

    Hill, Richard J.; Neubert, Matthias

    2003-01-01

    Soft-collinear effective theory is generalized to include soft massless quarks in addition to collinear fields. This extension is necessary for the treatment of interactions with the soft spectator quark in a heavy meson. The power counting of the relevant fields and the construction of the effective Lagrangian are discussed at leading order in Λ/m b . Several novel effects occur in the matching of full-theory amplitudes onto effective-theory operators containing soft light quarks, such as the appearance of an intermediate mass scale and large non-localities of operators on scales of order 1/Λ. Important examples of effective-theory operators with soft light quarks are studied and their renormalization properties explored. The formalism presented here forms the basis for a systematic analysis of factorization and power corrections for any exclusive B-meson decay into light particles

  1. Spectator Interactions in Soft-Collinear Effective Theory

    International Nuclear Information System (INIS)

    Hill, Richard J

    2002-01-01

    Soft-collinear effective theory is generalized to include soft massless quarks in addition to collinear fields. This extension is necessary for the treatment of interactions with the soft spectator quark in a heavy meson. The power counting of the relevant fields and the construction of the effective Lagrangian are discussed at leading order in Λ/m b . Several novel effects occur in the matching of full-theory amplitudes onto effective-theory operators containing soft light quarks, such as the appearance of an intermediate mass scale and large non-localities of operators on scales of order 1/Λ. Important examples of effective-theory operators with soft light quarks are studied and their renormalization properties explored. The formalism presented here forms the basis for a systematic analysis of factorization and power corrections for any exclusive B-meson decay into light particles

  2. Chameleon fragmentation

    Energy Technology Data Exchange (ETDEWEB)

    Brax, Philippe [Institut de Physique Théorique, CEA, IPhT, CNRS, URA 2306, F-91191Gif/Yvette Cedex (France); Upadhye, Amol, E-mail: philippe.brax@cea.fr, E-mail: aupadhye@anl.gov [Institute for the Early Universe, Ewha University, International Education, Building #601, 11-1, Daehyun-Dong Seodaemun-Gu, Seoul 120-750 (Korea, Republic of)

    2014-02-01

    A scalar field dark energy candidate could couple to ordinary matter and photons, enabling its detection in laboratory experiments. Here we study the quantum properties of the chameleon field, one such dark energy candidate, in an ''afterglow'' experiment designed to produce, trap, and detect chameleon particles. In particular, we investigate the possible fragmentation of a beam of chameleon particles into multiple particle states due to the highly non-linear interaction terms in the chameleon Lagrangian. Fragmentation could weaken the constraints of an afterglow experiment by reducing the energy of the regenerated photons, but this energy reduction also provides a unique signature which could be detected by a properly-designed experiment. We show that constraints from the CHASE experiment are essentially unaffected by fragmentation for φ{sup 4} and 1/φ potentials, but are weakened for steeper potentials, and we discuss possible future afterglow experiments.

  3. Chameleon fragmentation

    International Nuclear Information System (INIS)

    Brax, Philippe; Upadhye, Amol

    2014-01-01

    A scalar field dark energy candidate could couple to ordinary matter and photons, enabling its detection in laboratory experiments. Here we study the quantum properties of the chameleon field, one such dark energy candidate, in an ''afterglow'' experiment designed to produce, trap, and detect chameleon particles. In particular, we investigate the possible fragmentation of a beam of chameleon particles into multiple particle states due to the highly non-linear interaction terms in the chameleon Lagrangian. Fragmentation could weaken the constraints of an afterglow experiment by reducing the energy of the regenerated photons, but this energy reduction also provides a unique signature which could be detected by a properly-designed experiment. We show that constraints from the CHASE experiment are essentially unaffected by fragmentation for φ 4 and 1/φ potentials, but are weakened for steeper potentials, and we discuss possible future afterglow experiments

  4. Parton fragmentation in the vacuum and in the medium

    CERN Document Server

    Albino, S.; Arleo, F.; Besson, Dave Z.; Brooks, William K.; Buschbeck, B.; Cacciari, M.; Christova, E.; Corcella, G.; D'Enterria, David G.; Dolejsi, Jiri; Domdey, S.; Estienne, M.; Hamacher, Klaus; Heinz, M.; Hicks, K.; Kettler, D.; Kumano, S.; Moch, S.O.; Muccifora, V.; Pacetti, S.; Perez-Ramos, R.; Pirner, H.J.; Pronko, Alexandre Pavlovich; Radici, M.; Rak, J.; Roland, C.; Rudolph, Gerald; Rurikova, Z.; Salgado, C.A.; Sapeta, S.; Saxon, David H.; Seidl, Ralf-Christian; Seuster, R.; Stratmann, M.; Tannenbaum, Michael J.; Tasevsky, M.; Trainor, T.; Traynor, D.; Werlen, M.; Zhou, C.

    2008-01-01

    We present the mini-proceedings of the workshop on ``Parton fragmentation in the vacuum and in the medium'' held at the European Centre for Theoretical Studies in Nuclear Physics and Related Areas (ECT*, Trento) in February 2008. The workshop gathered both theorists and experimentalists to discuss the current status of investigations of quark and gluon fragmentation into hadrons at different accelerator facilities (LEP, B-factories, JLab, HERA, RHIC, and Tevatron) as well as preparations for extension of these studies at the LHC. The main physics topics covered were: (i) light-quark and gluon fragmentation in the vacuum including theoretical (global fits analyses and MLLA) and experimental (data from e+e-, p-p, e-p collisions) aspects, (ii) strange and heavy-quark fragmentation, (iii) parton fragmentation in cold QCD matter (nuclear DIS), and (iv) medium-modified fragmentation in hot and dense QCD matter (high-energy nucleus-nucleus collisions). These mini-proceedings consist of an introduction and short summ...

  5. Quark model with chiral-symmetry breaking and confinement in the Covariant Spectator Theory

    Energy Technology Data Exchange (ETDEWEB)

    Biernat, Elmer P. [CFTP, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal; Pena, Maria Teresa [CFTP, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal; Departamento de Física, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal; Ribiero, Jose' Emilio F. [CeFEMA, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal; Stadler, Alfred [Departamento de Física, Universidade de Évora, 7000-671 Évora, Portugal; Gross, Franz L. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-03-01

    We propose a model for the quark-antiquark interaction in Minkowski space using the Covariant Spectator Theory. We show that with an equal-weighted scalar-pseudoscalar structure for the confining part of our interaction kernel the axial-vector Ward-Takahashi identity is preserved and our model complies with the Adler-zero constraint for pi-pi-scattering imposed by chiral symmetry.

  6. Xenon spectator and diagram L3-M4,5M4,5 Auger intensities near the L3 threshold

    International Nuclear Information System (INIS)

    Armen, G.B.; Levin, J.C.; Southworth, S.H.; LeBrun, T.; Arp, U.; MacDonald, M.A.

    1997-01-01

    Calculations based on the theory of radiationless resonant Raman scattering are employed in the interpretation of new XeL 3 -M 4,5 M 4,5 Auger spectra recorded using synchrotron radiation tuned to energies across the L 3 edge. Fits of theoretical line shapes to the spectra are employed in separating intensities due to nd spectator (resonant) and diagram Auger processes. Near-threshold Auger intensity, previously attributed to diagram decay, is found to be due to the large-n spectator lines that result from postcollision-interaction endash induced open-quotes recaptureclose quotes of threshold photoelectrons to nd orbitals. copyright 1997 The American Physical Society

  7. Adam Smith, the Impartial Spectator and Embodiment: Towards an Economics of Accountability and Dialogue

    Directory of Open Access Journals (Sweden)

    Mark Rathbone

    2018-04-01

    Full Text Available This article argues that Adam Smith’s notion of sympathy and the impartial spectator in his work The Theory of Moral Sentiments [1759] connects the individual to society. In this work, Smith’s economics are far more complex than mere self-interest as a driver of commerce. Self-interest functions within a socio-ethical framework that limits excess and narcissism. However, morality was not based on normative assumptions for Smith and Hume. Morality was directly linked to social and cognitive processes in which the approbation of others was important. In other words, behaviour was based on the perceptions of others; therefore, action was to be adjusted to obtain sympathy. The impartial spectator refers to the cognitive process in which moral assessments are made. Therefore, the empiricism of Smith differs from determinism as related to physical causation because it operates through habituation and/or socialisation that can accommodate change and variation. Clearly, the socio-cultural presupposition of society directly influences the moral judgment of the individual. However, this deterministic tendency may result in an uncritical assessment of moral behaviour. To address this potential limitation of determinism, the embodied phenomenology of Merleau-Ponty is explored as an alternative theory which attempts to move beyond a dualism rooted in materialism/idealism. This perspective may expand on Smith’s economics by adding a more inclusive assessment of behaviour. Specifically, Merleau-Ponty’s corporeality provides a theory of behaviour that goes beyond a particular society’s perceptions of acceptable behaviour. This framework may provide the impartial spectator with a more encompassing perspective on moral assessment that may also be beneficial for sustainable commerce. It will be proposed that Merleau-Ponty’s embodied phenomenology and the hyper-dialectic of the flesh highlights the role of accountability and dialogue in moral assessment

  8. Target Immobilization as a Strategy for NMR-Based Fragment Screening: Comparison of TINS, STD, and SPR for Fragment Hit Identification

    NARCIS (Netherlands)

    Kobayashi, M.; Retra, K.; Figaroa, F.; Hollander, J.G.; Ab, E.; Heetebrij, R.J.; Irth, H.; Siegal, G.

    2010-01-01

    Fragment-based drug discovery (FBDD) has become a widely accepted tool that is complementary to high-throughput screening (HTS) in developing small-molecule inhibitors of pharmaceutical targets. Because a fragment campaign can only be as successful as the hit matter found, it is critical that the

  9. Densities and temperatures at fragment formation in heavy-ion collision

    Energy Technology Data Exchange (ETDEWEB)

    Ohnishi, Akira [Hokkaido Univ., Sapporo (Japan)

    1998-07-01

    In order to clarify whether the liquid-gas phase transition is relevant to the multi-fragment formation found in intermediate energy heavy-ion collisions, we estimate the densities and temperatures at fragment formation in Au+Au collisions at incident energies of 150 MeV/A and 400 MeV/A within the Quantum Molecular Dynamics (QMD) model with and without quantum fluctuations implemented according to the Quantal Langevin (QL) model. The calculated results show that the IMFs are mainly produced inside the unstable region of nuclear matter, which supports the idea of the fragment formation from supercooled nuclear matter. (author)

  10. Leaving Mango Street: Speech, Action and the Construction of Narrative in Britton's Spectator Stance

    Science.gov (United States)

    Crawford-Garrett, Katherine

    2009-01-01

    This paper attempts to unite "The House on Mango Street" by Sandra Cisneros with the participant and spectator theories of James Britton and D. W. Harding in the hopes that such a union will provide new insights into each. In particular, this article explores how the speech acts of Esperanza, the novel's protagonist, are indicative of a shifting…

  11. Hard spectator interactions in B {yields} {pi}{pi} at order {alpha}{sup 2}{sub s}

    Energy Technology Data Exchange (ETDEWEB)

    Pilipp, V.

    2007-05-31

    In the present thesis I discuss the hard spectator interaction amplitude in B {yields} {pi}{pi} at NLO i.e. at O({alpha}{sup 2}{sub s}). This special part of the amplitude, whose LO starts at O({alpha}{sub s}), is defined in the framework of QCD factorization. QCD factorization allows to separate the short- and the long-distance physics in leading power in an expansion in {lambda}{sub QCD}/m{sub b}, where the short-distance physics can be calculated in a perturbative expansion in {alpha}{sub s}. Compared to other parts of the amplitude hard spectator interactions are formally enhanced by the hard collinear scale {radical}({lambda}{sub QCD}m{sub b}), which occurs next to the mb-scale and leads to an enhancement of {alpha}{sub s}. From a technical point of view the main challenges of this calculation are due to the fact that we have to deal with Feynman integrals that come with up to five external legs and with three independent ratios of scales. These Feynman integrals have to be expanded in powers of {delta}{sub QCD}/m{sub b}. I discuss integration by parts identities to reduce the number of master integrals and differential equations techniques to get their power expansions. A concrete implementation of integration by parts identities in a computer algebra system is given in the appendix. Finally I discuss numerical issues like scale dependence of the amplitudes and branching ratios. It turns out that the NLO contributions of the hard spectator interactions are important but small enough for perturbation theory to be valid. (orig.)

  12. Fragmentation of relativistic nuclei

    International Nuclear Information System (INIS)

    Cork, B.

    1975-06-01

    Nuclei with energies of several GeV/n interact with hadrons and produce fragments that encompass the fields of nuclear physics, meson physics, and particle physics. Experimental results are now available to explore problems in nuclear physics such as the validity of the shell model to explain the momentum distribution of fragments, the contribution of giant dipole resonances to fragment production cross sections, the effective Coulomb barrier, and nuclear temperatures. A new approach to meson physics is possible by exploring the nucleon charge-exchange process. Particle physics problems are explored by measuring the energy and target dependence of isotope production cross sections, thus determining if limiting fragmentation and target factorization are valid, and measuring total cross sections to determine if the factorization relation, sigma/sub AB/ 2 = sigma/sub AA/ . sigma/sub BB/, is violated. Also, new experiments have been done to measure the angular distribution of fragments that could be explained as nuclear shock waves, and to explore for ultradense matter produced by very heavy ions incident on heavy atoms. (12 figures, 2 tables)

  13. On dark matter interactions with the Standard Model through an anomalous Z'

    Science.gov (United States)

    Ismail, Ahmed; Katz, Andrey; Racco, Davide

    2017-10-01

    We study electroweak scale Dark Matter (DM) whose interactions with baryonic matter are mediated by a heavy anomalous Z'. We emphasize that when the DM is a Majorana particle, its low-velocity annihilations are dominated by loop suppressed annihilations into the gauge bosons, rather than by p-wave or chirally suppressed annihilations into the SM fermions. Because the Z ' is anomalous, these kinds of DM models can be realized only as effective field theories (EFTs) with a well-defined cutoff, where heavy spectator fermions restore gauge invariance at high energies. We formulate these EFTs, estimate their cutoff and properly take into account the effect of the Chern-Simons terms one obtains after the spectator fermions are integrated out. We find that, while for light DM collider and direct detection experiments usually provide the strongest bounds, the bounds at higher masses are heavily dominated by indirect detection experiments, due to strong annihilation into W + W -, ZZ, Zγ and possibly into gg and γγ. We emphasize that these annihilation channels are generically significant because of the structure of the EFT, and therefore these models are prone to strong indirect detection constraints. Even though we focus on selected Z' models for illustrative purposes, our setup is completely generic and can be used for analyzing the predictions of any anomalous Z'-mediated DM model with arbitrary charges.

  14. Spectator interactions and factorization in $B \\to \\pi ell \

    CERN Document Server

    Beneke, Martin; Feldmann, Th.

    2004-01-01

    We investigate the factorization of different momentum modes that appear in matrix elements for exclusive B meson decays into light energetic particles for the specific case of B -> pi form factors at large pion recoil. We first integrate out hard modes with virtualities of order m_b^2 (m_b being the heavy quark mass), and then hard-collinear modes with virtualities m_b Lambda (Lambda being the strong interaction scale). The resulting effective theory contains soft and collinear fields with virtualities Lambda^2. We prove a previously conjectured factorization formula for B -> pi form factors in the heavy quark limit to all orders in alpha_s, paying particular attention to `endpoint singularities' that might have appeared in hard spectator interactions.

  15. Relativistic alpha-particles emitted in Fe-emulsion interactions at 1.7 A GeV

    International Nuclear Information System (INIS)

    Bhalla, K.B.; Chaudhry, M.; Lokanathan, S.; Grover, R.K.; Daftari, I.K.; Mangotra, L.L.; Rao, N.K.; Garpman, S.; Otterlund, I.

    1981-02-01

    Relativistic α-particles have been studied in 423 Fe-emulsion interactions at 1.7 A Gev. Comparisons of the observed angular distribution with that from 16 O-emulsion reactions at 2.1 A GeV reveal that more α particles are observed at large angles in the Fe-emulsion reactions. The α particles with large angles connot be explained by fragmentation from a clean cut spectator. Comparison of the experimental data with moving relativistic Boltzmann distributions shows that a single Boltzmann distribution cannot fit the fragmentation peak and the tail simultaneously. A thermal source (fireball) explaining the tail part of the distribution need to be formed by a mechanism other than simple clean cut participant-spectator picture. A large transverse momentum transfer to spectator before fragmentation may explain the tail. (author)

  16. The Spectator-Induced Electromagnetic Effect on Meson Production in Nucleus-Nucleus Collisions at SPS Energies

    Directory of Open Access Journals (Sweden)

    Rybicki Andrzej

    2012-12-01

    Full Text Available The electromagnetic interaction between the spectator system and the charged mesons produced in the course of the high energy heavy ion collision was studied experimentally and theoretically in earlier works [1,2]. This effect was found to result in very large distortions of the final state spectra of the produced mesons [3] and to bring new information on the space-time evolution of the non-perturbative meson production process [4]. In this paper a more extended analysis of this effect will be presented, including a comparative study between charged meson spectra produced in Pb+Pb collisions as well as collisions of Pb ions with smaller nuclei. The experimental results will be compared with Monte Carlo simulations, giving a fair overall understanding of the interplay between the strong and the electromagnetic interaction in the heavy ion collision. A universal behaviour of charged meson spectra emerges from the above comparative study. This gives a unique chance of using the spectator charge as a tool to study the space-time evolution of the high energy nucleus-nucleus reaction.

  17. Black Generation Y gender differences in Premier Soccer League spectator motives : sport marketing

    OpenAIRE

    T.E. Mofokeng; A.L. Bevan-Dye

    2014-01-01

    The purpose of this study was to determine whether there are gender differences concerning Premier Soccer League (PSL) spectator motives amongst black Generation Y students in South Africa. In South Africa, the black Generation Y cohort (individuals born between 1986 and 2005) represents an important but under-researched market segment in that, in 2013, they made up 32 percent of the country's population. From a PSL marketing perspective, understanding the motives that drive game spectatorshi...

  18. Spectator tagging in quasi-free pn-reactions on deuterium at PROMICE/WASA, CELSIUS

    CERN Document Server

    Bilger, R; Calén, H; Clement, H; Dunin, V; Dyring, J; Ekström, C; Fransson, K; Greiff, J; Gustafsson, L; Häggström, S; Hoeistad, B; Johanson, J; Johansson, A; Johansson, T; Khoukaz, A; Kilian, K; Koch, I; Kullander, Sven; Kupsc, A; Marciniewski, P; Morosov, B; Neubauer, T; Oelert, W; Ruber, Roger J M Y; Shwartz, B A; Stepaniak, J; Sukhanov, A; Sukhanov, A; Sundberg, P; Turowiecki, A; Wagner, G; Wilhelmi, Z; Wilkin, C; Zabierowski, J; Zernov, A; Zlomanczuk, Yu

    2000-01-01

    A set of silicon detectors has been added to the PROMICE/WASA (P/W) experiment at CELSIUS. These detectors have been used for spectator-proton tagging in proton deuteron collisions to investigate proton-neutron reactions at intermediate energies. The performance of the setup has been tested by measuring the pd -> d pi sup o p sub s sub p sub e sub c sub t sub a sub t sub o sub r reaction

  19. The Pursuit of Memory: Examining Art Teaching and Pedagogical Practices through Hannah Arendt's Actor-Spectator Theory

    Science.gov (United States)

    Lee, Mun Yee

    2011-01-01

    Memories of our schooling and teaching experiences shape our curriculum and pedagogical decision-making process in art education when we become teachers and teacher educators. In this paper, using Hannah Arendt's Actor-Spectator Theory, I engage in retrospective critical introspection of my practices as an art teacher and curriculum developer in…

  20. Educar espectadores: propuestas expositivas y dinamización To educate spectators: expositive proposals and dynamization

    Directory of Open Access Journals (Sweden)

    María Isabel Moreno Montoso

    2007-03-01

    Full Text Available Reflexionar acerca de la adaptación del espectador a las últimas tendencias de las artes visuales y del mundo de la imagen en general es el objetivo de este trabajo que nos lleva a considerar la necesidad de ayudar a la población a situarse como espectadores críticos. Esta propuesta se apoya en el desarrollo de acciones, algunas ya experimentadas, dirigidas al público para conseguir un aprendizaje activo. La motivación a partir de la implicación personal de los participantes debe ser el centro de interés en las actividades de las correspondientes acciones. This paper is a reflection on the adaptation of the spectator to the latest tendencies in plastic art and image in general. This reflection leads up to consider the need for helping the audience to become critical spectators. This proposal is based on the development of activities, some of which have already been put in to practice, which are aimed at the audience with the goal of producing an active learning process. Apart from the participants´ personal involvement, motivation should be the focus of the activities.

  1. SAPhIR: a fission-fragment detector

    International Nuclear Information System (INIS)

    Theisen, Ch.; Gautherin, C.; Houry, M.; Korten, W.; Le Coz, Y.; Lucas, R.; Barreau, G.; Doan, T. P.; Belier, G.; Meot, V.; Ethvignot, Th.; Cahan, B.; Le Coguie, A.; Coppolani, X.; Delaitre, B.; Le Bourlout, P.; Legou, Ph.; Maillard, O.; Durand, G.; Bouillac, A.

    1998-01-01

    SAPhIR is the acronym for S a clay A q uitaine P ho tovoltaic cells for I s omer R e search. It consists of solar cells, used for fission-fragment detection. It is a collaboration between 3 laboratories: CEA Saclay, CENBG Bordeaux and CEA Bruyeres le Chatel. The coupling of a highly efficient fission-fragment detector like SAPhIR with EUROBALL will provide new insights in the study of very deformed nuclear matter and in the spectroscopy of neutron-rich nuclei

  2. Probing Pb+Pb collisions at √sNN = 2.76 TeV with spectator neutrons in AMPT model

    International Nuclear Information System (INIS)

    Mohanty, Bedangadas; Bairathi, Vipul; Haque, Md. Rihan; Chatterjee, Sandeep

    2016-01-01

    In high energy heavy-ion collisions a precise knowledge of the initial state is required in order to describe properties of the strongly interacting medium. There is event by event geometric as well as quantum fluctuations in the initial condition of heavy-ion collisions. The standard technique of analyzing heavy-ion collisions in bins of centrality obtained from final state multiplicity averages out the various initial configurations and thus restricts the study to only a limited range of initial conditions. In this work, we propose an additional binning in terms of total spectator neutrons (L+R), which is sum of left (L) and right (R) going spectator neutrons in an event. This offers us a key control parameter to probe events with broader range of initial conditions providing us an opportunity to investigate events with rarer initial conditions which otherwise get masked when analyzed by centrality binning alone

  3. Interaction of the radiation with matter

    International Nuclear Information System (INIS)

    2013-01-01

    This third chapter presents the ionization, excitation, activation and radiation breaking; radiation directly and indirectly ionizing; interaction of the electromagnetic radiation with matter; interaction of neutrons with matter; interaction of radiation directly ionizing with matter; interaction of electrons with matter, interaction of alpha particle with matter; interaction of fission fragments with matter; travel time and integrated processes of interaction: energy dissipation

  4. Rape as Spectator Sport and Creepshot Entertainment: Social Media and the Valorization of Lack of Consent

    Directory of Open Access Journals (Sweden)

    Kelly Oliver

    2016-10-01

    Full Text Available Lack of consent is valorized within popular culture to the point that sexual assault has become a spectator sport and creepshot entertainment on social media. Indeed, the valorization of nonconsensual sex has reached the extreme where sex with unconscious girls, especially accompanied by photographs as trophies, has become a goal of some boys and men.

  5. THE EFFECT OF MEDIA LITERACY ON THE SOCIAL IDENTITY OF VOLLEYBALL SPECTATORS THROUGH PERSONAL IDENTITY

    OpenAIRE

    Mahsa Nematzadeh

    2017-01-01

    This research aim was investigating the effect of media literacy on volleyball spectator's social identity through personal identity. The present study, psychologically, is divided in to 8 layers of view paradigm, the main type of applied research: deductive research approaches, quantity research strategies theories, field research tone, cross sectional survey methods, research objectives, description and finally data collection methods, library resource reviews, and questionnaires. The stati...

  6. From Golden Age Mexican Cinema to Transnational Border Feminism: The Community of Spectators in "Loving Pedro Infante"

    Science.gov (United States)

    Heredia, Juanita

    2008-01-01

    The novel "Loving Pedro Infante" by Chicana writer Denise Chavez provides an insightful transcultural feminist critique of Golden Age Mexican cinema culture through a careful examination of gender roles. In the novel, the reception of Pedro Infante's films by spectators bridges generations and national spaces and leads to the formation…

  7. Heavy and Heavy-Light Mesons in the Covariant Spectator Theory

    Science.gov (United States)

    Stadler, Alfred; Leitão, Sofia; Peña, M. T.; Biernat, Elmar P.

    2018-05-01

    The masses and vertex functions of heavy and heavy-light mesons, described as quark-antiquark bound states, are calculated with the Covariant Spectator Theory (CST). We use a kernel with an adjustable mixture of Lorentz scalar, pseudoscalar, and vector linear confining interaction, together with a one-gluon-exchange kernel. A series of fits to the heavy and heavy-light meson spectrum were calculated, and we discuss what conclusions can be drawn from it, especially about the Lorentz structure of the kernel. We also apply the Brodsky-Huang-Lepage prescription to express the CST wave functions for heavy quarkonia in terms of light-front variables. They agree remarkably well with light-front wave functions obtained in the Hamiltonian basis light-front quantization approach, even in excited states.

  8. Breakup of spectator residues in relativistic nuclear collisions

    International Nuclear Information System (INIS)

    Warwick, A.I.; Wieman, H.H.; Gutbrod, H.H.

    1983-01-01

    Low energy nuclear fragments (12 4 He, and 20 Ne projectiles are measured to yield information on the breakup of the target nucleus. We discuss the shapes of the fragment energy spectra across this broad range of fragment mass and pick out the fission component by its binary breakup. Multiplicities of coincident fast charged particles are presented as a measure of the degree of violence of the initial stage of the collision. Angular distributions of light fragments (8< or =Z< or =11) give the average velocities imparted to the residue in central collisions, and these values are compared to the results of cascade calculations. Measurements of slow fragment multiplicities from central events reveal a many-fragment final state. In the light of this finding we develop a simple calculation of the Coulomb features of the observed spectra. The applicability of a statistical breakup model is discussed

  9. [Cardiac arrest in spectators in German football stadiums. Precautionary measures, frequency and short-term outcome].

    Science.gov (United States)

    Luiz, T; Preisegger, T; Rombach, D; Madler, C

    2014-09-01

    Provision of medical care is an important element of safety precautions for visitors of sports arenas. The organizational requirements are especially high if cardiac arrest occurs; how this scenario is managed may thus serve as the ultimate indicator of the quality of stadium medical care. The objectives of this study were to analyze the structures and the resources available for the medical care of spectators in German professional soccer stadiums and to identify the frequency and the primary resuscitation success of cardiac arrest. In 2011 a questionnaire-based survey was performed among the clubs of the first and second German soccer leagues regarding medical care of spectators during the seasons 2008/2009 and 2009/2010. The focus was on the qualifications of emergency teams, the equipment and the incidence of cardiac arrest. A total of 15 stadiums were included (38%) in the survey. The mean number of physicians and emergency medical technicians on site was 0.6/10,000 seats and 16/10,000 seats, respectively. Of the latter, a mean of 82% (minimum 20% and maximum 100%) had received training with automatic external defibrillators. In 87% of the stadiums regular advanced life support training (ALS) was required. The mean number of defibrillators per stadium was 2.8/10,000 seats (minimum 1.3 and maximum 3.8) including 1.7 automatic defibrillators (minimum 0.4 and maximum 2.8). For patient transport, a mean of 0.65 ALS ambulance vehicles per 10,000 seats (minimum 0.14 and maximum 1.46) were available on site. In all stadiums staff members were connected via mobile radio communication with the stadium medical control room. A total of 52 cardiac arrests (=0.25/100,000 spectators) were recorded of which 96% of the patients were transported to hospitals with spontaneous circulation. Cardiac arrests are not a rare occurrence in German soccer stadiums. The participating stadiums are overall well prepared for such incidents in terms of organization, staff and technology and

  10. Simulation of a relativistic heavy ions beam transport in the matter: contribution of the fragmentation process and biological implications; Simulation du transport d`un faisceau d`ions lourds relativistes dans la matiere: contribution du processus de fragmentation et implication sur le plan biologique

    Energy Technology Data Exchange (ETDEWEB)

    Ibnouzahir, M

    1995-03-01

    The study of relativistic heavy ion collisions permit an approach of the properties of dense and not hadronic matter, and an analysis of the reaction mechanisms. Such studies are also interesting on the biological point of view, since there exist now well defined projects concerning the radiotherapy with high LET particles as neutrons, protons, heavy ions. It is thus necessary to have a good understanding of the processes which occur in the propagation of a relativistic heavy ion beam (E{>=} 100 A.MeV) in matter. We have elaborated a three dimensional transport code, using a Monte Carlo method, in order to describe the propagation of Ne and Ar ions in water. Violent nuclear collisions giving fragmentation process have been taken into account by use of the FREESCO program. We have tested the validity of our transport model and we show an important change of the energy deposition at the vicinity of the Bragg peak; such a distortion, due mainly to fragmentation reactions, is of a great interest for biological applications. (author).

  11. Collective flow measured with the Plastic Ball

    International Nuclear Information System (INIS)

    Ritter, H.G.; Gutbrod, H.H.; Kampert, K.H.; Kolb, B.; Poskanzer, A.M.; Schicker, R.; Schmidt, H.R.; Siemiarczuk, T.

    1989-08-01

    The experimental results from the Plastic Ball detector have contributed vastly to the understanding of the reaction mechanism of nuclear collisions at several hundred MeV per nucleon. The discovery of the collective flow phenomena (bounce-off of spectator fragments, side-splash in the reaction plane, and squeeze-out out of the reaction plane), as they were predicted by hydrodynamical models, has led to the experimental observation of compressed nuclear matter, which is a necessary condition before one can study the equation of state in detail and search for phase transitions at higher energies. 39 refs., 9 figs., 1 tab

  12. Mass yield distributions for the reactions Ca+Ca, Nb+Nb and Ca+Ca at E/A=800 MeV in the molecular-dynamical model

    International Nuclear Information System (INIS)

    Kiselev, S.M.

    1987-01-01

    Mass yield distributions obtained on the basis of the molecular-dynamical model are presented for the Ca+Ca, Nb+Nb reactions at E/A=400 MeV and Ca+Ca reaction at E/A=800 MeV. For the fragments with masses upto quarter of the mass of initial nucleus the model predicts a power law for mass spectra with almost the same value of the exponent. Such the behaviour is roughly a result of the superposition of the fireball breakup and the disintegration of spectator regions rather than the evidence of a liquid-gas-like phase transition in hot nuclear matter

  13. "1"2C fragmentation on thin targets at 95 MeV/A study for hadrontherapy

    International Nuclear Information System (INIS)

    Dudouet, Jeremie

    2014-01-01

    The nuclear models need to be improved in order to reach the required accuracy for a reference simulation code for hadrontherapy. In this context, two experiments have been performed by our collaboration on May 2011 and September 2013 at GANIL to study nuclear reactions of 95 MeV/u "1"2C ions on thin targets of medical interest to measure the double differential fragmentation cross sections of each produced isotope. These experimental data have been compared with Monte-Carlo simulations. Different nuclear models provided by the GEANT4 simulation toolkit have firstly been tested. These simulations revealed discrepancies up to one order of magnitude. The phenomenological model HIPSE has then been used and has shown that the overlapping region of two colliding nuclei needs to be taken into account in order to reproduce the kinematics of the emitted fragments at intermediates energies. Due to the difficulties encountered by these models in the data reproduction, a new model is currently under development: SLIIPIE. This one is a semi-microscopic model, built from a participant-spectator geometrical approach. This model was also compared to the experimental data for "1"2C+"1"2C reactions at 95 MeV/A giving promising results. (author) [fr

  14. Scholars in the Nineties: Actors, Subjects, Spectators or Hostages?

    Directory of Open Access Journals (Sweden)

    Manuel Gil Antón

    2000-05-01

    Full Text Available Dr. Gil questions the role played by Mexican university academics in the transformation of higher education during the nineties. After outlining the general context of change and its importance, the author proposes avoiding the false dichotomy between restoring the past or installing, without reflective mediation, a schematic future. He suggests taking into consideration the current national academic body composed of several generations of scholars. Three phases are established in terms of the modification of academic activities during the last decades of the twentieth century, and the changes in the level of higher education are considered. Dr. Gil asks if the academics have been actors, subjects, spectators or hostages-both in regard to regulations governing their activity and in the modifications of university processes and structure. The essay ends by proposing a general agenda for research in the field of university studies, and emphasizes two problems: the need for a detailed description of the type and depth of changes, and the definition of the academic as a central actor in institutional life. 

  15. The mass (charge) spectrum of superheavy nuclei fission fragments: the new perspectives for the theory of nucleosynthesis

    International Nuclear Information System (INIS)

    Maslyuk, V.T.

    2012-01-01

    A new approach to the problem of nucleosynthesis based on assumption of a nuclear matter or superheavy nuclei series fragmentation up to atomic nuclei is proposed. It is shown that studies of the mass (charge) fragments yields (MCFY) after nuclear matter disintegration is possible within proposed statistical theory. The data of MCFY calculation for exotic superheavy nuclei multifragmentation with A=300, 900 and 1200 and arbitrary Z values are demonstrated

  16. Explosion-evaporation model for fragment production in intermediate-energy nuclear collisions

    International Nuclear Information System (INIS)

    Fai, G.; Randrup, J.

    1981-01-01

    Nuclear collisions at intermediate energies may create transient systems of hot nuclear matter that decay into many nuclear fragments. The disassembly of such a nuclear fireball is described as a two-stage process. In the primary explosion stage the system quickly fragments into nucleons and composite nuclei according to the available phase space. The explosion produces excited nuclei with half-lives longer than the time associated with the breakup. In the secondary evaporation stage, these nuclei decay, first by sequential emission of light particles (neutrons, protons, alphas), later by electromagnetic radiation. The secondary stage in general changes the relative abundancies of the various fragment species. This general feature makes it essential to take account of the composite fragments before using d/p as a measure of the entropy of the initial source. The formation of unbound nuclei at the explosion stage also has the desirable effect of enhancing the final abundancies of particularly stable nuclei, e.g., 4 He. For neutron-excessive sources the presence of composite nuclei amplifies the ratio of observed neutrons and protons; this effect persists for heavier mirror systems. Predictions of the model are qualitatively compared to available experimental data. The model offers a convenient way to augment existing dynamical models, such as intra-nuclear cascade and nuclear fluid dynamics, to yield actual nuclear fragments rather than merely matter distributions

  17. First spatial isotopic separation of relativistic uranium projectile fragments

    International Nuclear Information System (INIS)

    Magel, A.; Voss, B.; Armbruster, P.; Aumann, T.; Clerc, H.G.; Czajkowski, S.; Folger, H.; Grewe, A.; Hanelt, E.; Heinz, A.; Irnich, H.; Jong, M. de; Junghans, A.; Nickel, F.; Pfuetzner, M.; Roehl, C.; Scheidenberger, C.; Schmidt, K.H.; Schwab, W.; Steinhaeuser, S.; Suemmerer, K.; Trinder, W.; Wollnik, H.

    1994-07-01

    Spatial isotopic separation of relativistic uranium projectile fragments has been achieved for the first time. The fragments were produced in peripheral nuclear collisions and spatially separated in-flight with the fragment separator FRS at GSI. A two-fold magnetic-rigidity analysis was applied exploiting the atomic energy loss in specially shaped matter placed in the dispersive central focal plane. Systematic investigations with relativistic projectiles ranging from oxygen up to uranium demonstrate that the FRS is a universal and powerful facility for the production and in-flight separation of monoisotopic, exotic secondary beams of all elements up to Z=92. This achievement has opened a new area in heavy-ion research and applications. (orig.)

  18. Antiproton Induced Fission and Fragmentation of Nuclei

    CERN Multimedia

    2002-01-01

    The annihilation of slow antiprotons with nuclei results in a large highly localized energy deposition primarily on the nuclear surface. \\\\ \\\\ The study of antiproton induced fission and fragmentation processes is expected to yield new information on special nuclear matter states, unexplored fission modes, multifragmentation of nuclei, and intranuclear cascades.\\\\ \\\\ In order to investigate the antiproton-nucleus interaction and the processes following the antiproton annihilation at the nucleus, we propose the following experiments: \\item A)~Measurement of several fragments from fission and from multifragmentation in coincidence with particle spectra, especially neutrons and kaons. \\item B)~Precise spectra of $\\pi$, K, n, p, d and t with time-of-flight techniques. \\item C)~Installation of the Berlin 4$\\pi$ neutron detector with a 4$\\pi$ Si detector placed inside for fragments and charged particles. This yields neutron multiplicity distributions and consequently distributions of thermal excitation energies and...

  19. Breakup conditions of projectile spectators from dynamical observables

    Energy Technology Data Exchange (ETDEWEB)

    Begemann-Blaich, M.; Lindenstruth, V.; Pochodzalla, J. [and others

    1998-03-01

    Momenta and masses of heavy projectile fragments (Z {>=} 8), produced in collisions of {sup 197}Au with C, Al, Cu and Pb targets at E/A=600 MeV, were determined with the ALADIN magnetic spectrometer at SIS. Using these informations, an analysis of kinematic correlations between the two and three heaviest projectile fragments in their rest frame was performed. The sensitivity of these correlations to the conditions at breakup was verified within the schematic SOS-model. For a quantitative investigation, the data were compared to calculations with statistical multifragmentation models and to classical three-body calculations. With classical trajectory calculations, where the charges and masses of the fragments are taken from a Monte Carlo sampling of the experimental events, the dynamical observables can be reproduced. The deduced breakup parameters, however, differ considerably from those assumed in the statistical multifragmentation models which describe the charge correlations. If, on the other hand, the analysis of kinematic and charge correlations is performed for events with two and three heavy fragments produced by statistical multifragmentation codes, a good agreement with the data is found with the exception that the fluctuation widths of the intrinsic fragment energies are significantly underestimated. A new version of the multifragmentation code MCFRAG was therefore used to investigate the potential role of angular momentum at the breakup stage. If a mean angular momentum of 0.75 {Dirac_h}/nucleon is added to the system, the energy fluctuations can be reproduced, but at the same time the charge partitions are modified and deviate from the data. (orig.)

  20. Breakup conditions of projectile spectators from dynamical observables

    International Nuclear Information System (INIS)

    Begemann-Blaich, M.; Lindenstruth, V.; Pochodzalla, J.

    1998-03-01

    Momenta and masses of heavy projectile fragments (Z ≥ 8), produced in collisions of 197 Au with C, Al, Cu and Pb targets at E/A=600 MeV, were determined with the ALADIN magnetic spectrometer at SIS. Using these informations, an analysis of kinematic correlations between the two and three heaviest projectile fragments in their rest frame was performed. The sensitivity of these correlations to the conditions at breakup was verified within the schematic SOS-model. For a quantitative investigation, the data were compared to calculations with statistical multifragmentation models and to classical three-body calculations. With classical trajectory calculations, where the charges and masses of the fragments are taken from a Monte Carlo sampling of the experimental events, the dynamical observables can be reproduced. The deduced breakup parameters, however, differ considerably from those assumed in the statistical multifragmentation models which describe the charge correlations. If, on the other hand, the analysis of kinematic and charge correlations is performed for events with two and three heavy fragments produced by statistical multifragmentation codes, a good agreement with the data is found with the exception that the fluctuation widths of the intrinsic fragment energies are significantly underestimated. A new version of the multifragmentation code MCFRAG was therefore used to investigate the potential role of angular momentum at the breakup stage. If a mean angular momentum of 0.75 ℎ/nucleon is added to the system, the energy fluctuations can be reproduced, but at the same time the charge partitions are modified and deviate from the data. (orig.)

  1. Differential cross section study of fragment production, at small angle, in relativistic heavy ion collisions. Application at a calculation of heavy ion beam transport in the matter

    International Nuclear Information System (INIS)

    Morel, P.

    1992-02-01

    Relativistic heavy ion collisions present the opportunity of creating in laboratory small volumes of hot, dense nuclear matter. On the experimental point of view, the collision events are characterized by a great number of fragments, especially in the direction of the projectile. The first part is devoted to a survey of relativistic heavy ion physics. Then, we present two experimental set-ups which permit, in particular, the analyse of light fragment production at small angles. We present experimental results concerning light projectiles on Ca, Nb, Pb targets, with energies from 200 A.MeV up to 600 A.MeV. Different aspects of the collision are put in evidence. Momentum and charge differential cross section are extrapolated to other projectile/target systems; that is used in a transport calculation of Ne ions in a target of biological interest (water), with a collimator. We show that nuclear fragmentation produces a dispersion in the spatial and energy distributions, and that one light fragments have a range greater than the projectile range. That last point causes a distortion of the Bragg curve, and that distortion must be taken into account for the application of heavy ions to radiotherapy problems. 95 figs., 8 tabs

  2. Some like it hot: Spectators who score high on the personality trait openness enjoy the excitement of hearing dancers breathing without music

    Directory of Open Access Journals (Sweden)

    Corinne eJola

    2014-09-01

    Full Text Available An integral part of dance is music. Over the last ten years, however, dance stimuli have been repeatedly used to study action observation processes without music, increasing our understanding of the influence of observer’s physical abilities on action perception. Moreover, beyond trained skills and empathy traits, very little has been investigated on how other observer or spectators’ properties modulate action observation and action preference. Since strong correlations have been shown between music and personality traits, here we aim to investigate how personality traits shape the appreciation of dance when this is presented with 3 different music/sounds. Therefore, we investigated the relationship between personality traits and the subjective aesthetic experience of 52 spectators watching a 24 min lasting contemporary dance performance projected on a big screen containing three movement phrases performed to three different sound scores: classical music (i.e. Bach, an electronic sound-score, and a section without music but where the breathing of the performers was audible. We found that first, spectators rated the experience of watching dance without music significantly different from with music. Second, we found that the higher spectators scored on the Big Five personality factor openness, the more they liked the no-music section. Third, spectators’ physical experience with dance was not linked to their appreciation but was significantly related to high average extravert scores. For the first time, we showed that spectators’ reported entrainment to watching dance movements without music is strongly related to their personality and thus may need to be considered when using dance as a means to investigate action observation processes and aesthetic preferences.

  3. The Bonus Detector: A Radial Time Projection Chamber for tracking Spectator Protons

    International Nuclear Information System (INIS)

    Howard Fenker

    2004-01-01

    A GEM-based Radial Time Projection Chamber is being developed as a spectator-proton tracker for an experiment at Jefferson Lab. The purpose of the experiment is the study of the structure of nearly free neutrons. Interactions on such neutrons can be identified by the presence of a backward-moving proton in the final state of a beam-deuterium collision. The detector must be of very low mass in order to provide sensitivity to the slowest possible protons. The ionization electron trail left by the protons will drift radially outward to an amplification structure composed of curved GEMs, and the resulting charge will be collected on pads on the outer layer of the detector. Unique design challenges are imposed by the cylindrical geometry and the low mass requirement. The status of the project and results of prototype tests are presented

  4. The spectator on the images meantime of The ballad of sexual dependency O espectador no entretempo das imagens de The ballad of sexual dependency

    Directory of Open Access Journals (Sweden)

    Juliana Salles Siqueira

    2012-01-01

    Full Text Available By attempting to the intermedial character Nan Goldins several works - and specifically of her slide show The ballad of sexual dependency (1979-, this paper intends to indicate the peculiar way in which the artist dialectize images of her personal collection, mobilizing the spectator for an active work in the meantime and intervals of the photographs displayed. The consideration of the intermedial aspects of her work and the return to the Didi Hubermans concept of dialectical images (1998 allow us to think about the process by which the photographer gives legibility to the pictures of her archive and invokes the spectators to draw their own set of associations and dissociations. We retake, at this point of our argument, to the theme of spectators emancipation as raised by Jacques Rancire (2008.Ao atentar para o carter intermedial formador de vrias obras de Nan Goldin e, em especfico, do diaporama The ballad of sexual dependency (1979, o presente artigo procura indicar o modo peculiar como a artista dialetiza as imagens de seu acervo pessoal, mobilizando o espectador para um trabalho ativo nos intervalos e entretempos das fotografias exibidas. A considerao dos aspectos intermiditicos de sua obra e o retorno ao conceito de imagens dialticas proposto por Didi-Huberman (1998 permitem-nos compreender o processo pelo qual a fotgrafa d legibilidade a suas fotografias de arquivo, bem como convoca o espectador a elaborar seu prprio jogo de associaes e dissociaes. Retomamos, neste ponto de nosso argumento, o tema da emancipao do espectador conforme suscitado por Jacques Rancire (2008.

  5. Thermal inflation with a thermal waterfall scalar field coupled to a light spectator scalar field

    Science.gov (United States)

    Dimopoulos, Konstantinos; Lyth, David H.; Rumsey, Arron

    2017-05-01

    A new model of thermal inflation is introduced, in which the mass of the thermal waterfall field is dependent on a light spectator scalar field. Using the δ N formalism, the "end of inflation" scenario is investigated in order to ascertain whether this model is able to produce the dominant contribution to the primordial curvature perturbation. A multitude of constraints are considered so as to explore the parameter space, with particular emphasis on key observational signatures. For natural values of the parameters, the model is found to yield a sharp prediction for the scalar spectral index and its running, well within the current observational bounds.

  6. “Some like it hot”: spectators who score high on the personality trait openness enjoy the excitement of hearing dancers breathing without music

    Science.gov (United States)

    Jola, Corinne; Pollick, Frank E.; Calvo-Merino, Beatriz

    2014-01-01

    Music is an integral part of dance. Over the last 10 years, however, dance stimuli (without music) have been repeatedly used to study action observation processes, increasing our understanding of the influence of observer’s physical abilities on action perception. Moreover, beyond trained skills and empathy traits, very little has been investigated on how other observer or spectators’ properties modulate action observation and action preference. Since strong correlations have been shown between music and personality traits, here we aim to investigate how personality traits shape the appreciation of dance when this is presented with three different music/sounds. Therefore, we investigated the relationship between personality traits and the subjective esthetic experience of 52 spectators watching a 24 min lasting contemporary dance performance projected on a big screen containing three movement phrases performed to three different sound scores: classical music (i.e., Bach), an electronic sound-score, and a section without music but where the breathing of the performers was audible. We found that first, spectators rated the experience of watching dance without music significantly different from with music. Second, we found that the higher spectators scored on the Big Five personality factor openness, the more they liked the no-music section. Third, spectators’ physical experience with dance was not linked to their appreciation but was significantly related to high average extravert scores. For the first time, we showed that spectators’ reported entrainment to watching dance movements without music is strongly related to their personality and thus may need to be considered when using dance as a means to investigate action observation processes and esthetic preferences. PMID:25309393

  7. Spectator scattering at NLO in non-leptonic B decays: Leading penguin amplitudes

    International Nuclear Information System (INIS)

    Beneke, M.; Jaeger, S.

    2007-01-01

    We complete the computation of the 1-loop (α s 2 ) corrections to hard spectator scattering in non-leptonic B decays at leading power in Λ/m b by evaluating the penguin amplitudes. This extends the knowledge of these next-to-next-to-leading-order contributions in the QCD factorization formula for B decays to a much wider class of final states, including all pseudoscalar-pseudoscalar, pseudoscalar-vector, and longitudinally polarized vector-vector final states, except final states with η or η ' mesons. The new 1-loop correction is significant for the colour-suppressed amplitudes, but turns out to be strongly suppressed for the leading QCD penguin amplitude α 4 p . We provide numerical values of the phenomenological P/T and C/T amplitude ratios for the ππ, πρ and ρρ final states, and discuss corrections to several relations between electroweak penguin and tree amplitudes

  8. Proton, deuteron, and triton emission at target rapidity in Au+Au collisions at 10.20A GeV: Spectra and directed flow

    International Nuclear Information System (INIS)

    Ashktorab, K.; Beavis, D.; Chasman, C.; Chen, Z.; Chu, Y.Y.; Cumming, J.B.; Debbe, R.; Gonin, M.; Gushue, S.; Levine, M.; Moskowitz, B.; Olness, J.; Remsberg, L.P.; Tannenbaum, M.J.; Videbaek, F.; Zhu, F.; Crawford, H.J.; Engelage, J.; Judd, E.; Chang, J.; Eldredge, W.; Fung, S.Y.; Seto, R.; Xu, G.; Zhu, Q.; Chi, C.; Cole, B.A.; Moulson, M.; Nagamiya, S.; Nayak, T.K.; Wang, F.Q.; Wang, Y.; Wu, Y.; Zajc, W.A.; Akiba, Y.; Hamagaki, H.; Homma, S.; Sako, H.; Kaneko, H.; Britt, H.C.; Cianciolo, V.; Luke, J.; Namboodiri, M.N.; Sangster, T.C.; Soltz, R.; Thomas, J.H.; Tonse, S.R.; Ahle, L.; Baker, M.D.; Heintzelman, G.; Ogilvie, C.A.; Steadman, S.G.; Stephans, G.S.; Sung, T.; Woodruff, D.S.; Zachary, D.; Hayano, R.S.; Shigaki, K.; Kumagai, A.; Kurita, K.; Miake, Y.; Ueno-Hayashi, S.; Yagi, K.; Kang, J.H.; Gaardhoje, J.J.; Hansen, A.G.; Hansen, L.

    1998-01-01

    Systematic results are presented on proton, deuteron, and triton emission from the target spectator region in collisions of 10.20A GeV gold projectiles with a gold target. A forward hodoscope utilizes detection of projectile spectator fragments to determine the orientation of the reaction plane, event by event. The directed flow left-angle p x right-angle is determined as a function of pseudorapidity. Projectile spectator energy is used to estimate impact parameters. Results are compared to current theoretical models ARC, ART, and RQMD. In all cases good agreement with theory is obtained for calculations utilizing a pure cascade without nuclear potential contributions. copyright 1998 The American Physical Society

  9. Projectile fragmentation of a weakly-bound 11Be nucleus at 0.8 GeV/nucleon

    International Nuclear Information System (INIS)

    Kobayashi, T.

    1990-01-01

    The projectile fragmentation of a weakly-bound 11 Be projectile has been measured on a carbon target at 0.8 GeV/nucleon. The transverse momentum distribution of 10 Be fragments showed a two-Gaussian structure: a narrow component with σ ∼ 25 MeV/c on top of a wide component with σ ∼ 110 MeV/c. As in the case of 11 Li fragmentation, the narrow momentum distribution indicates a long tail in the neutron density distribution which is consistent with the large nuclear matter radius of the 11 Be nucleus. Neutrons were also measured in coincidence with 10 Be fragments. In contrast to 10 Be fragments, no narrow momentum distribution was observed for coincident neutrons

  10. Off-shell effects in the model of spectator electroproduction of cumulative nucleons; Ehffekty skhoda s massovoj poverkhnosti v modeli spektatornogo obrazovaniya kumulyativnykh nuklonov

    Energy Technology Data Exchange (ETDEWEB)

    Sargsyan, M M

    1992-12-31

    The effects of deeply bound nucleons are considered in the reaction of deuteron quasielastic electro disintegration, where the spectator nucleon and scattered electrons are registered in coincidence. Both, the off-shell influence on the description of nucleon motion in nuclear surrounding and the modification of deeply bound nucleon form - factors are investigated as two aspects of the off-shell effect manifestation. The possibility to control the extent of interacting nucleon binding energy by varying the spectator nucleon kinematic parameters (p{sub s},{theta}{sub s},{phi}{sub s}) is an advantage of the reactions considered. The cross section ratios of these processes are considered under specific kinematical conditions, which allow to investigate unambiguously the manifestations of deeply bound effects. To estimate the extent of the phenomena expected, we present the results of calculation of R ratios in the framework of models that take the off-shell effects into account differently. The effects of bound nucleon form - factor modification are estimated according to the model of mini delocalization, which predicts the bound nucleon swelling in nuclear environment. 28 refs.

  11. Study of charge correlation for Z {<=} 2 obtained in Au+Au collisions with incident energy from 150 up to 400 MeV/A. FOPI detector is used; Etude des correlations des charges Z {<=} 2 obtenues lors des collisions Au+Au aux energies incidentes de 150 a 400 MeV/A avec le detecteur fopi

    Energy Technology Data Exchange (ETDEWEB)

    Pras, Ph

    1997-01-24

    In the first part of this work we present what information can be driven from heavy ion collision studies and what can be expected from the state equation of nuclear matter. We introduce the notion of centrality and the concept of spectator-participant. The different models of collisions are reviewed. The theory of correlations between light particles is used as a tool to predict some results about the shape and population density of theoretical spectra.The Coulomb model which implies a thermal interpretation of heavy ion collisions is modified in order to take excited states into account and to reproduce the collective phenomena of flow and squeeze-out. Within the frame of this modified Coulomb model 3 notions of nuclear temperature are compared. A discussion is lead to find out the temperature of nuclear matter at the very moment of fragmentation. (A.C.) 134 refs.

  12. Directed flow of charged particles at mid-rapidity relative to the spectator plane in Pb-Pb collisions at $\\sqrt{s_{NN}}$=2.76 TeV

    CERN Document Server

    Abelev, Betty; Adamova, Dagmar; Adare, Andrew Marshall; Aggarwal, Madan; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agocs, Andras Gabor; Agostinelli, Andrea; Ahammed, Zubayer; Ahmad, Nazeer; Ahmad, Arshad; Ahmed, Ijaz; Ahn, Sul-Ah; Ahn, Sang Un; Aimo, Ilaria; Ajaz, Muhammad; Akindinov, Alexander; Aleksandrov, Dmitry; Alessandro, Bruno; Alexandre, Didier; Alici, Andrea; Alkin, Anton; Alme, Johan; Alt, Torsten; Altini, Valerio; Altinpinar, Sedat; Altsybeev, Igor; Andrei, Cristian; Andronic, Anton; Anguelov, Venelin; Anielski, Jonas; Anson, Christopher Daniel; Anticic, Tome; Antinori, Federico; Antonioli, Pietro; Aphecetche, Laurent Bernard; Appelshauser, Harald; Arbor, Nicolas; Arcelli, Silvia; Arend, Andreas; Armesto, Nestor; Arnaldi, Roberta; Aronsson, Tomas Robert; Arsene, Ionut Cristian; Arslandok, Mesut; Asryan, Andzhey; Augustinus, Andre; Averbeck, Ralf Peter; Awes, Terry; Aysto, Juha Heikki; Azmi, Mohd Danish; Bach, Matthias Jakob; Badala, Angela; Baek, Yong Wook; Bailhache, Raphaelle Marie; Bala, Renu; Baldisseri, Alberto; Baltasar Dos Santos Pedrosa, Fernando; Ban, Jaroslav; Baral, Rama Chandra; Barbera, Roberto; Barile, Francesco; Barnafoldi, Gergely Gabor; Barnby, Lee Stuart; Barret, Valerie; Bartke, Jerzy Gustaw; Basile, Maurizio; Bastid, Nicole; Basu, Sumit; Bathen, Bastian; Batigne, Guillaume; Batyunya, Boris; Batzing, Paul Christoph; Baumann, Christoph Heinrich; Bearden, Ian Gardner; Beck, Hans; Behera, Nirbhay Kumar; Belikov, Iouri; Bellini, Francesca; Bellwied, Rene; Belmont-Moreno, Ernesto; Bencedi, Gyula; Beole, Stefania; Berceanu, Ionela; Bercuci, Alexandru; Berdnikov, Yaroslav; Berenyi, Daniel; Bergognon, Anais Annick Erica; Bertens, Redmer Alexander; Berzano, Dario; Betev, Latchezar; Bhasin, Anju; Bhati, Ashok Kumar; Bhom, Jihyun; Bianchi, Livio; Bianchi, Nicola; Bianchin, Chiara; Bielcik, Jaroslav; Bielcikova, Jana; Bilandzic, Ante; Bjelogrlic, Sandro; Blanco, Francesco; Blanco, F; Blau, Dmitry; Blume, Christoph; Boccioli, Marco; Bock, Friederike Bock; Boettger, Stefan; Bogdanov, Alexey; Boggild, Hans; Bogolyubsky, Mikhail; Boldizsar, Laszlo; Bombara, Marek; Book, Julian; Borel, Herve; Borissov, Alexander; Bossu, Francesco; Botje, Michiel; Botta, Elena; Braidot, Ermes; Braun-Munzinger, Peter; Bregant, Marco; Breitner, Timo Gunther; Broker, Theo Alexander; Browning, Tyler Allen; Broz, Michal; Brun, Rene; Bruna, Elena; Bruno, Giuseppe Eugenio; Budnikov, Dmitry; Buesching, Henner; Bufalino, Stefania; Buncic, Predrag; Busch, Oliver; Buthelezi, Edith Zinhle; Caffarri, Davide; Cai, Xu; Caines, Helen Louise; Caliva, Alberto; Calvo Villar, Ernesto; Camerini, Paolo; Canoa Roman, Veronica; Cara Romeo, Giovanni; Carena, Francesco; Carena, Wisla; Carlin Filho, Nelson; Carminati, Federico; Casanova Diaz, Amaya Ofelia; Castillo Castellanos, Javier Ernesto; Castillo Hernandez, Juan Francisco; Casula, Ester Anna Rita; Catanescu, Vasile; Cavicchioli, Costanza; Ceballos Sanchez, Cesar; Cepila, Jan; Cerello, Piergiorgio; Chang, Beomsu; Chapeland, Sylvain; Charvet, Jean-Luc Fernand; 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Dash, Sadhana; De, Sudipan; de Barros, Gabriel; De Caro, Annalisa; de Cataldo, Giacinto; de Cuveland, Jan; De Falco, Alessandro; De Gruttola, Daniele; Delagrange, Hugues; Deloff, Andrzej; De Marco, Nora; Denes, Ervin; De Pasquale, Salvatore; Deppman, Airton; D'Erasmo, Ginevra; de Rooij, Raoul Stefan; Diaz Corchero, Miguel Angel; Di Bari, Domenico; Dietel, Thomas; Di Giglio, Carmelo; Di Liberto, Sergio; Di Mauro, Antonio; Di Nezza, Pasquale; Divia, Roberto; Djuvsland, Oeystein; Dobrin, Alexandru Florin; Dobrowolski, Tadeusz Antoni; Donigus, Benjamin; Dordic, Olja; Dubey, Anand Kumar; Dubla, Andrea; Ducroux, Laurent; Dupieux, Pascal; Dutta Majumdar, AK; Elia, Domenico; Elwood, Brian Gerard; Emschermann, David Philip; Engel, Heiko; Erazmus, Barbara; Erdal, Hege Austrheim; Eschweiler, Dominic; Espagnon, Bruno; Estienne, Magali Danielle; Esumi, Shinichi; Evans, David; Evdokimov, Sergey; Eyyubova, Gyulnara; Fabris, Daniela; Faivre, Julien; Falchieri, Davide; Fantoni, Alessandra; Fasel, Markus; Fehlker, Dominik; Feldkamp, Linus; Felea, Daniel; Feliciello, Alessandro; Fenton-Olsen, Bo; Feofilov, Grigory; Fernandez Tellez, Arturo; Ferretti, Alessandro; Festanti, Andrea; Figiel, Jan; Figueredo, Marcel; Filchagin, Sergey; Finogeev, Dmitry; Fionda, Fiorella; Fiore, Enrichetta Maria; Floratos, Emmanuel; Floris, Michele; Foertsch, Siegfried Valentin; Foka, Panagiota; Fokin, Sergey; Fragiacomo, Enrico; Francescon, Andrea; Frankenfeld, Ulrich Michael; Fuchs, Ulrich; Furget, Christophe; Fusco Girard, Mario; Gaardhoje, Jens Joergen; Gagliardi, Martino; Gago, Alberto; Gallio, Mauro; Gangadharan, Dhevan Raja; Ganoti, Paraskevi; Garabatos, Jose; Garcia-Solis, Edmundo; Gargiulo, Corrado; Garishvili, Irakli; Gerhard, Jochen; Germain, Marie; Gheata, Andrei George; Gheata, Mihaela; Ghidini, Bruno; Ghosh, Premomoy; Gianotti, Paola; Giubellino, Paolo; Gladysz-Dziadus, Ewa; Glassel, Peter; Goerlich, Lidia; Gomez, Ramon; Gonzalez Ferreiro, Elena; Gonzalez-Zamora, Pedro; Gorbunov, Sergey; Goswami, Ankita; Gotovac, Sven; Graczykowski, Lukasz Kamil; Grajcarek, Robert; Grelli, Alessandro; Grigoras, Alina Gabriela; Grigoras, Costin; Grigoriev, Vladislav; Grigoryan, Ara; Grigoryan, Smbat; Grinyov, Boris; Grion, Nevio; Gros, Philippe; Grosse-Oetringhaus, Jan Fiete; Grossiord, Jean-Yves; Grosso, Raffaele; Guber, Fedor; Guernane, Rachid; Guerzoni, Barbara; Guilbaud, Maxime Rene Joseph; Gulbrandsen, Kristjan Herlache; Gulkanyan, Hrant; Gunji, Taku; Gupta, Anik; Gupta, Ramni; Haake, Rudiger; Haaland, Oystein Senneset; Hadjidakis, Cynthia Marie; Haiduc, Maria; Hamagaki, Hideki; Hamar, Gergoe; Han, Byounghee; Hanratty, Luke David; Hansen, Alexander; Harris, John William; Harton, Austin; Hatzifotiadou, Despoina; Hayashi, Shinichi; Hayrapetyan, Arsen; Heckel, Stefan Thomas; Heide, Markus Ansgar; Helstrup, Haavard; Herghelegiu, Andrei Ionut; Herrera Corral, Gerardo Antonio; Herrmann, Norbert; Hess, Benjamin Andreas; Hetland, Kristin Fanebust; Hicks, Bernard; Hippolyte, Boris; Hori, Yasuto; Hristov, Peter Zahariev; Hrivnacova, Ivana; Huang, Meidana; Humanic, Thomas; Hwang, Dae Sung; Ichou, Raphaelle; Ilkaev, Radiy; Ilkiv, Iryna; Inaba, Motoi; Incani, Elisa; Innocenti, Pier Giorgio; Innocenti, Gian Michele; Ionita, Costin; Ippolitov, Mikhail; Irfan, Muhammad; Ivanov, Vladimir; Ivanov, Marian; Ivanov, Andrey; Ivanytskyi, Oleksii; Jacholkowski, Adam Wlodzimierz; Jacobs, Peter; Jahnke, Cristiane; Jang, Haeng Jin; Janik, Malgorzata Anna; Jayarathna, Sandun; Jena, Satyajit; Jha, Deeptanshu Manu; Jimenez Bustamante, Raul Tonatiuh; Jones, Peter Graham; Jung, Hyung Taik; Jusko, Anton; Kaidalov, Alexei; Kalcher, Sebastian; Kalinak, Peter; Kalliokoski, Tuomo Esa Aukusti; Kalweit, Alexander Philipp; Kang, Ju Hwan; Kaplin, Vladimir; Kar, Somnath; Karasu Uysal, Ayben; Karavichev, Oleg; Karavicheva, Tatiana; Karpechev, Evgeny; Kazantsev, Andrey; Kebschull, Udo Wolfgang; Keidel, Ralf; Ketzer, Bernhard Franz; Khan, Mohisin Mohammed; Khan, Palash; Khan, Kamal Hussain; Khan, Shuaib Ahmad; Khanzadeev, Alexei; Kharlov, Yury; 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Malaev, Mikhail; Maldonado Cervantes, Ivonne Alicia; Malinina, Ludmila; Mal'Kevich, Dmitry; Malzacher, Peter; Mamonov, Alexander; Manceau, Loic Henri Antoine; Mangotra, Lalit Kumar; Manko, Vladislav; Manso, Franck; Manzari, Vito; Marchisone, Massimiliano; Mares, Jiri; Margagliotti, Giacomo Vito; Margotti, Anselmo; Marin, Ana Maria; Markert, Christina; Marquard, Marco; Martashvili, Irakli; Martin, Nicole Alice; Martin Blanco, Javier; Martinengo, Paolo; Martinez, Mario Ivan; Martinez Garcia, Gines; Martynov, Yevgen; Mas, Alexis Jean-Michel; Masciocchi, Silvia; Masera, Massimo; Masoni, Alberto; Massacrier, Laure Marie; Mastroserio, Annalisa; Matyja, Adam Tomasz; Mayer, Christoph; Mazer, Joel; Mazumder, Rakesh; Mazzoni, Alessandra Maria; Meddi, Franco; Menchaca-Rocha, Arturo Alejandro; Mercado Perez, Jorge; Meres, Michal; Miake, Yasuo; Mikhaylov, Konstantin; Milano, Leonardo; Milosevic, Jovan; Mischke, Andre; Mishra, Aditya Nath; Miskowiec, Dariusz; Mitu, Ciprian Mihai; Mlynarz, Jocelyn; Mohanty, Bedangadas; 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Schutz, Yves Roland; Schwarz, Kilian Eberhard; Schweda, Kai Oliver; Scioli, Gilda; Scomparin, Enrico; Scott, Patrick Aaron; Scott, Rebecca; Segato, Gianfranco; Selyuzhenkov, Ilya; Senyukov, Serhiy; Seo, Jeewon; Serci, Sergio; Serradilla, Eulogio; Sevcenco, Adrian; Shabetai, Alexandre; Shabratova, Galina; Shahoyan, Ruben; Sharma, Natasha; Sharma, Satish; Sharma, Rohni; Shigaki, Kenta; Shtejer, Katherin; Sibiriak, Yury; Siddhanta, Sabyasachi; Siemiarczuk, Teodor; Silvermyr, David Olle Rickard; Silvestre, Catherine; Simatovic, Goran; Simonetti, Giuseppe; Singaraju, Rama Narayana; Singh, Ranbir; Singha, Subhash; Singhal, Vikas; Sinha, Tinku; Sinha, Bikash; Sitar, Branislav; Sitta, Mario; Skaali, Bernhard; Skjerdal, Kyrre; Smakal, Radek; Smirnov, Nikolai; Snellings, Raimond; Sogaard, Carsten; Soltz, Ron Ariel; Song, Jihye; Song, Myunggeun; Soos, Csaba; Soramel, Francesca; Spacek, Michal; Sputowska, Iwona; Spyropoulou-Stassinaki, Martha; Srivastava, Brijesh Kumar; Stachel, Johanna; Stan, Ionel; Stefanek, Grzegorz; Steinpreis, Matthew; Stenlund, Evert Anders; Steyn, Gideon Francois; Stiller, Johannes Hendrik; Stocco, Diego; Stolpovskiy, Mikhail; Strmen, Peter; Suaide, Alexandre Alarcon do Passo; Subieta Vasquez, Martin Alfonso; Sugitate, Toru; Suire, Christophe Pierre; Suleymanov, Mais; Sultanov, Rishat; Sumbera, Michal; Susa, Tatjana; Symons, Timothy; Szanto de Toledo, Alejandro; Szarka, Imrich; Szczepankiewicz, Adam; Szymanski, Maciej; Takahashi, Jun; Tangaro, Marco-Antonio; Tapia Takaki, Daniel Jesus; Tarantola Peloni, Attilio; Tarazona Martinez, Alfonso; Tauro, Arturo; Tejeda Munoz, Guillermo; Telesca, Adriana; Ter-Minasyan, Astkhik; Terrevoli, Cristina; Thader, Jochen Mathias; Thomas, Deepa; Tieulent, Raphael Noel; Timmins, Anthony; Tlusty, David; Toia, Alberica; Torii, Hisayuki; Toscano, Luca; Trubnikov, Victor; Truesdale, David Christopher; Trzaska, Wladyslaw Henryk; Tsuji, Tomoya; Tumkin, Alexandr; Turrisi, Rosario; Tveter, Trine Spedstad; Ulery, Jason Glyndwr; Ullaland, Kjetil; Ulrich, Jochen; Uras, Antonio; Urciuoli, Guido Marie; Usai, Gianluca; Vajzer, Michal; Vala, Martin; Valencia Palomo, Lizardo; Vallero, Sara; Vande Vyvre, Pierre; Van Hoorne, Jacobus Willem; van Leeuwen, Marco; Vannucci, Luigi; Vargas, Aurora Diozcora; Varma, Raghava; Vasileiou, Maria; Vasiliev, Andrey; Vechernin, Vladimir; Veldhoen, Misha; Venaruzzo, Massimo; Vercellin, Ermanno; Vergara, Sergio; Vernet, Renaud; Verweij, Marta; Vickovic, Linda; Viesti, Giuseppe; Viinikainen, Jussi; Vilakazi, Zabulon; Villalobos Baillie, Orlando; Vinogradov, Yury; Vinogradov, Alexander; Vinogradov, Leonid; Virgili, Tiziano; Viyogi, Yogendra; Vodopianov, Alexander; Volkl, Martin Andreas; Voloshin, Kirill; Voloshin, Sergey; Volpe, Giacomo; von Haller, Barthelemy; Vorobyev, Ivan; Vranic, Danilo; Vrlakova, Janka; Vulpescu, Bogdan; Vyushin, Alexey; Wagner, Boris; Wagner, Vladimir; Wagner, Jan; Wang, Yaping; Wang, Mengliang; Wang, Yifei; Watanabe, Daisuke; Watanabe, Kengo; Weber, Michael; Wessels, Johannes; Westerhoff, Uwe; Wiechula, Jens; Wielanek, Daniel; Wikne, Jon; Wilde, Martin Rudolf; Wilk, Grzegorz Andrzej; Wilkinson, Jeremy; Williams, Crispin; Winn, Michael Winn; Windelband, Bernd Stefan; Xiang, Changzhou; Yaldo, Chris G; Yamaguchi, Yorito; Yang, Hongyan; Yang, Shiming; Yang, Ping; Yano, Satoshi; Yasnopolsky, Stanislav; Yi, JunGyu; Yin, Zhongbao; Yoo, In-Kwon; Yoon, Jongik; Yushmanov, Igor; Zaccolo, Valentina; Zach, Cenek; Zampolli, Chiara; Zaporozhets, Sergey; Zarochentsev, Andrey; Zavada, Petr; Zaviyalov, Nikolai; Zbroszczyk, Hanna Paulina; Zelnicek, Pierre; Zgura, Sorin Ion; Zhalov, Mikhail; Zhang, Yonghong; Zhang, Xiaoming; Zhang, Fan; Zhang, Haitao; Zhou, You; Zhou, Fengchu; Zhou, Daicui; Zhu, Hongsheng; Zhu, Xiangrong; Zhu, Jianlin; Zhu, Jianhui; Zichichi, Antonino; Zimmermann, Alice; Zinovjev, Gennady; Zoccarato, Yannick Denis; Zynovyev, Mykhaylo; Zyzak, Maksym

    2013-12-06

    The directed flow of charged particles at midrapidity is measured in Pb-Pb collisions at $\\sqrt{s_{NN}}$=2.76 TeV relative to the collision plane defined by the spectator nucleons. Both, the rapidity odd ($v_1^{odd}$) and even ($v_1^{even}$) directed flow components are reported. The $v_1^{odd}$ component has a negative slope as a function of pseudorapidity similar to that observed at the highest RHIC energy, but with about a three times smaller magnitude. The $v_1^{even}$ component is found to be non-zero and independent of pseudorapidity. Both components show little dependence on the collision centrality and change sign at transverse momenta around 1.2-1.7 GeV/c for midcentral collisions. The shape of $v_1^{even}$ as a function of transverse momentum and a vanishing transverse momentum shift along the spectator deflection for $v_1^{even}$ are consistent with dipole-like initial density fluctuations in the overlap zone of the nuclei.

  13. Measurement of the Neutron F2 Structure Function via Spectator Tagging with CLAS

    Science.gov (United States)

    Baillie, N.; Tkachenko, S.; Zhang, J.; Bosted, P.; Bültmann, S.; Christy, M. E.; Fenker, H.; Griffioen, K. A.; Keppel, C. E.; Kuhn, S. E.; Melnitchouk, W.; Tvaskis, V.; Adhikari, K. P.; Adikaram, D.; Aghasyan, M.; Amaryan, M. J.; Anghinolfi, M.; Arrington, J.; Avakian, H.; Baghdasaryan, H.; Battaglieri, M.; Biselli, A. S.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Cole, P. L.; Contalbrigo, M.; Crede, V.; D'Angelo, A.; Daniel, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Deur, A.; Dey, B.; Djalali, C.; Dodge, G.; Domingo, J.; Doughty, D.; Dupre, R.; Dutta, D.; Ent, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fegan, S.; Fradi, A.; Gabrielyan, M. Y.; Gevorgyan, N.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Gohn, W.; Golovatch, E.; Gothe, R. W.; Graham, L.; Guegan, B.; Guidal, M.; Guler, N.; Guo, L.; Hafidi, K.; Heddle, D.; Hicks, K.; Holtrop, M.; Hungerford, E.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Ispiryan, M.; Isupov, E. L.; Jawalkar, S. S.; Jo, H. S.; Kalantarians, N.; Khandaker, M.; Khetarpal, P.; Kim, A.; Kim, W.; King, P. M.; Klein, A.; Klein, F. J.; Klimenko, A.; Kubarovsky, V.; Kuleshov, S. V.; Kvaltine, N. D.; Livingston, K.; Lu, H. Y.; MacGregor, I. J. D.; Mao, Y.; Markov, N.; McKinnon, B.; Mineeva, T.; Morrison, B.; Moutarde, H.; Munevar, E.; Nadel-Turonski, P.; Ni, A.; Niccolai, S.; Niculescu, I.; Niculescu, G.; Osipenko, M.; Ostrovidov, A. I.; Pappalardo, L.; Park, K.; Park, S.; Pasyuk, E.; Anefalos Pereira, S.; Pisano, S.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Prok, Y.; Protopopescu, D.; Raue, B. A.; Ricco, G.; Rimal, D.; Ripani, M.; Rosner, G.; Rossi, P.; Sabatié, F.; Saini, M. S.; Salgado, C.; Schott, D.; Schumacher, R. A.; Seder, E.; Sharabian, Y. G.; Sober, D. I.; Sokhan, D.; Stepanyan, S.; Stepanyan, S. S.; Stoler, P.; Strauch, S.; Taiuti, M.; Tang, W.; Ungaro, M.; Vineyard, M. F.; Voutier, E.; Watts, D. P.; Weinstein, L. B.; Weygand, D. P.; Wood, M. H.; Zana, L.; Zhao, B.

    2012-04-01

    We report on the first measurement of the F2 structure function of the neutron from the semi-inclusive scattering of electrons from deuterium, with low-momentum protons detected in the backward hemisphere. Restricting the momentum of the spectator protons to ≲100MeV/c and their angles to ≳100° relative to the momentum transfer allows an interpretation of the process in terms of scattering from nearly on-shell neutrons. The F2n data collected cover the nucleon-resonance and deep-inelastic regions over a wide range of Bjorken x for 0.65

  14. Model of Structural Fragmentation Induced by High Pressure Torsion

    Czech Academy of Sciences Publication Activity Database

    Kratochvíl, J.; Kružík, Martin; Sedláček, R.

    2010-01-01

    Roč. 25, č. 1 (2010), s. 88-98 ISSN 1606-5131 Institutional research plan: CEZ:AV0Z10750506 Keywords : High-pressure torsion * intergranular glide * homogeneous deformation mode Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.649, year: 2010 http://library.utia.cas.cz/separaty/2010/MTR/kruzik-model of structural fragmentation induced by high pressure torsion.pdf

  15. Fragment-based lead generation: identification of seed fragments by a highly efficient fragment screening technology

    Science.gov (United States)

    Neumann, Lars; Ritscher, Allegra; Müller, Gerhard; Hafenbradl, Doris

    2009-08-01

    For the detection of the precise and unambiguous binding of fragments to a specific binding site on the target protein, we have developed a novel reporter displacement binding assay technology. The application of this technology for the fragment screening as well as the fragment evolution process with a specific modelling based design strategy is demonstrated for inhibitors of the protein kinase p38alpha. In a fragment screening approach seed fragments were identified which were then used to build compounds from the deep-pocket towards the hinge binding area of the protein kinase p38alpha based on a modelling approach. BIRB796 was used as a blueprint for the alignment of the fragments. The fragment evolution of these deep-pocket binding fragments towards the fully optimized inhibitor BIRB796 included the modulation of the residence time as well as the affinity. The goal of our study was to evaluate the robustness and efficiency of our novel fragment screening technology at high fragment concentrations, compare the screening data with biochemical activity data and to demonstrate the evolution of the hit fragments with fast kinetics, into slow kinetic inhibitors in an in silico approach.

  16. Fragmentation of Protein Kinase N (PKN) in the Hydrocephalic Rat Brain

    International Nuclear Information System (INIS)

    Okii, Norifumi; Amano, Taku; Seki, Takahiro; Matsubayashi, Hiroaki; Mukai, Hideyuki; Ono, Yoshitaka; Kurisu, Kaoru; Sakai, Norio

    2007-01-01

    PKN (protein kinase N; also called protein kinase C-related kinase (PRK-1)), is a serine/threonine protein kinase that is ubiquitously expressed in several organs, including the brain. PKN has a molecular mass of 120 kDa and has two domains, a regulatory and a catalytic domain, in its amino-terminals and carboxyl-terminus, respectively. Although the role of PKN has not been fully elucidated, previous studies have revealed that PKN is cleaved to a constitutively active catalytic fragment of 55 kDa in response to apoptotic signals. Hydrocephalus is a pathological condition caused by insufficient cerebrospinal fluid (CSF) circulation and subsequent excess of CSF in the brain. In this study, in order to elucidate the role of PKN in the pathophysiology of hydrocephalus, we examined PKN fragmentation in hydrocephalic model rats. Hydrocephalus was induced in rats by injecting kaolin into the cisterna magna. Kaolin-induced rats (n=60) were divided into three groups according to the observation period after treatment (group 1: 3–6 weeks, group 2: 7–12 weeks, and group 3: 13–18 weeks). Sham-treated control rats, injected with sterile saline (n=20), were similarly divided into three groups. Spatial learning ability was estimated by a modified water maze test. Thereafter, brains were cut into slices and ventricular dilatation was estimated. Fragmentation of PKN was observed by Western blotting in samples collected from the parietal cortex, striatum, septal nucleus, hippocampus, and periaqueductal gray matter. All kaolin-induced rats showed ventricular dilatation. Most of them showed less spatial learning ability than those of sham-treated controls. In most regions, fragmentation of PKN had occurred in a biphasic manner more frequently than that in controls. The appearance of PKN fragmentation in periaqueductal gray matter was correlated with the extent of ventricular dilation and spatial learning disability. These results revealed that PKN fragmentation was observed in

  17. Gray Matter Hypertrophy and Thickening with Obstructive Sleep Apnea in Middle-aged and Older Adults.

    Science.gov (United States)

    Baril, Andrée-Ann; Gagnon, Katia; Brayet, Pauline; Montplaisir, Jacques; De Beaumont, Louis; Carrier, Julie; Lafond, Chantal; L'Heureux, Francis; Gagnon, Jean-François; Gosselin, Nadia

    2017-06-01

    Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly assessed by neuroimaging. To investigate whether markers of obstructive sleep apnea severity are associated with gray matter changes among middle-aged and older individuals. Seventy-one subjects (ages, 55-76 yr; apnea-hypopnea index, 0.2-96.6 events/h) were evaluated by magnetic resonance imaging. Two techniques were used: (1) voxel-based morphometry, which measures gray matter volume and concentration; and (2) FreeSurfer (an open source software suite) automated segmentation, which estimates the volume of predefined cortical/subcortical regions and cortical thickness. Regression analyses were performed between gray matter characteristics and markers of obstructive sleep apnea severity (hypoxemia, respiratory disturbances, and sleep fragmentation). Subjects had few symptoms, that is, sleepiness, depression, anxiety, and cognitive deficits. Although no association was found with voxel-based morphometry, FreeSurfer revealed increased gray matter with obstructive sleep apnea. Higher levels of hypoxemia correlated with increased volume and thickness of the left lateral prefrontal cortex as well as increased thickness of the right frontal pole, the right lateral parietal lobules, and the left posterior cingulate cortex. Respiratory disturbances positively correlated with right amygdala volume, and more severe sleep fragmentation was associated with increased thickness of the right inferior frontal gyrus. Gray matter hypertrophy and thickening were associated with hypoxemia, respiratory disturbances, and sleep fragmentation. These structural changes in a group of middle-aged and older individuals may represent adaptive/reactive brain mechanisms attributed to a presymptomatic stage of obstructive sleep apnea.

  18. Studies of complex fragment emission in heavy ion reactions

    International Nuclear Information System (INIS)

    Charity, R.J.; Sobotka, L.G.

    1993-01-01

    The study of intermediate-energy heavy-ion nuclear reactions is reported. This work has two foci: the properties of nuclear matter under abnormal conditions, in this energy domain, predominately low densities and the study of the relevant reaction mechanisms. Nuclear matter properties, such as phase transitions, are reflected in the dynamics of the reactions. The process leads to an understanding of the reaction mechanism themselves and therefore to the response characteristics of finite, perhaps non-equilibrium, strongly interacting systems. The program has the following objectives: to study energy, mass, and angular momentum deposition by studying incomplete fusion reactions; to gain confidence in the understanding of how highly excited systems decompose by studying all emissions from the highly excited systems; to push these kinds of studies into the intermediate energy domain (where intermediate mass fragment emission is not improbable) with excitation function studies; and to learn about the dynamics of the decays using particle-particle correlations. The last effort focuses on simple systems, where definitive statements are possible. These avenues of research share a common theme, large complex fragment production. It is this feature, more than any other, which distinguishes the intermediate energy domain

  19. Measurement of the structure function of the nearly free neutron using spectator tagging in inelastic 2H(e ,e'ps )X scattering with CLAS

    Science.gov (United States)

    Tkachenko, S.; Baillie, N.; Kuhn, S. E.; Zhang, J.; Arrington, J.; Bosted, P.; Bültmann, S.; Christy, M. E.; Fenker, H.; Griffioen, K. A.; Kalantarians, N.; Keppel, C. E.; Melnitchouk, W.; Tvaskis, V.; Adhikari, K. P.; Aghasyan, M.; Amaryan, M. J.; Anefalos Pereira, S.; Avakian, H.; Ball, J.; Baltzell, N. A.; Battaglieri, M.; Bedlinskiy, I.; Biselli, A. S.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Cole, P. L.; Contalbrigo, M.; Cortes, O.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Deur, A.; Djalali, C.; Dodge, G. E.; Doughty, D.; Dupre, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fleming, J. A.; Garillon, B.; Gevorgyan, N.; Ghandilyan, Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Golovatch, E.; Gothe, R. W.; Guidal, M.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Harrison, N.; Hattawy, M.; Hicks, K.; Ho, D.; Holtrop, M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Jo, H. S.; Keller, D.; Khandaker, M.; Kim, A.; Kim, W.; King, P. M.; Klein, A.; Klein, F. J.; Koirala, S.; Kubarovsky, V.; Kuleshov, S. V.; Lenisa, P.; Lewis, S.; Livingston, K.; Lu, H.; MacCormick, M.; MacGregor, I. J. D.; Markov, N.; Mayer, M.; McKinnon, B.; Mineeva, T.; Mirazita, M.; Mokeev, V.; Montgomery, R. A.; Moutarde, H.; Munoz Camacho, C.; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Pappalardo, L. L.; Paremuzyan, R.; Park, K.; Pasyuk, E.; Phillips, J. J.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Protopopescu, D.; Puckett, A. J. R.; Rimal, D.; Ripani, M.; Rizzo, A.; Rosner, G.; Rossi, P.; Roy, P.; Sabatié, F.; Schott, D.; Schumacher, R. A.; Seder, E.; Senderovich, I.; Sharabian, Y. G.; Simonyan, A.; Smith, G. D.; Sober, D. I.; Sokhan, D.; Stepanyan, S.; Stepanyan, S. S.; Strauch, S.; Tang, W.; Ungaro, M.; Vlassov, A. V.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Watts, D.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zana, L.; Zonta, I.; CLAS Collaboration

    2014-04-01

    Background: Much less is known about neutron structure than that of the proton due to the absence of free neutron targets. Neutron information is usually extracted from data on nuclear targets such as deuterium, requiring corrections for nuclear binding and nucleon off-shell effects. These corrections are model dependent and have significant uncertainties, especially for large values of the Bjorken scaling variable x . As a consequence, the same data can lead to different conclusions, for example, about the behavior of the d quark distribution in the proton at large x . Purpose: The Barely Off-shell Nucleon Structure experiment at Jefferson Lab measured the inelastic electron-deuteron scattering cross section, tagging spectator protons in coincidence with the scattered electrons. This method reduces nuclear binding uncertainties significantly and has allowed for the first time a (nearly) model-independent extraction of the neutron structure function F2(x ,Q2) in the resonance and deep-inelastic regions. Method: A novel compact radial time projection chamber was built to detect protons with momentum between 70 and 150 MeV/c and over a nearly 4 π angular range. For the extraction of the free-neutron structure function F2n, spectator protons at backward angles (>100∘ relative to the momentum transfer) and with momenta below 100 MeV/c were selected, ensuring that the scattering took place on a nearly free neutron. The scattered electrons were detected with Jefferson Lab's CLAS spectrometer, with data taken at beam energies near 2, 4, and 5 GeV. Results: The extracted neutron structure function F2n and its ratio to the inclusive deuteron structure function F2d are presented in both the resonance and the deep-inelastic regions for momentum transfer squared Q2 between 0.7 and 5 GeV2/c2 , invariant mass W between 1 and 2.7 GeV/c2 , and Bjorken x between 0.25 and 0.6 (in the deep-inelastic scattering region). The dependence of the semi-inclusive cross section on the

  20. Multiple parton scattering in nuclei: heavy quark energy loss and modified fragmentation functions

    International Nuclear Information System (INIS)

    Zhang Benwei; Wang, Enke; Wang Xinnian

    2005-01-01

    Multiple scattering, induced radiative energy loss and modified fragmentation functions of a heavy quark in nuclear matter are studied within the framework of generalized factorization in perturbative QCD. Modified heavy quark fragmentation functions and energy loss are derived in detail with illustration of the mass dependencies of the Landau-Pomeranchuk-Migdal interference effects and heavy quark energy loss. Due to the quark mass dependence of the gluon formation time, the nuclear size dependencies of nuclear modification of the heavy quark fragmentation function and heavy quark energy loss are found to change from a linear to a quadratic form when the initial energy and momentum scale are increased relative to the quark mass. The radiative energy loss of the heavy quark is also significantly suppressed due to limited cone of gluon radiation imposed by the mass. Medium modification of the heavy quark fragmentation functions is found to be limited to the large z region due to the form of heavy quark fragmentation functions in vacuum

  1. Sun-protective Behaviors of Student Spectators at Inter-school Swimming Carnivals in a Tropical Region of High Ambient Solar Ultraviolet Radiation.

    Directory of Open Access Journals (Sweden)

    Denise Turner

    2016-08-01

    Full Text Available Skin cancer is the most common cancer in humans and Australia (particularly in Queensland has the highest incidence globally. Sunlight is a known skin carcinogen and reflects off water, exacerbating the risk of sunburn. In 1988, the SunSmart Program was developed to promote sun-protection to Australian children. Within a decade, it evolved to include a voluntary national accreditation program for schools, known as the SunSmart Schools (SSS Program. Additionally, in 2008, it became compulsory for primary schoolchildren attending Queensland government-funded schools to wear a shirt during all water-based activities, except when competing. We observed the proportion of student spectators from 41 Townsville (latitude 19.3°S primary schools (65.9% SSS wearing hats at inter-school swimming carnivals in 2009-2011 and 2015 and the proportion wearing a shirt. Overall, a median of 30.7% student spectators from each school wore a hat (max 46.2% [2009]; min 18% [2015] and 77.3% wore a shirt (max 95.8% [2009]; min 74.5% [2015], suggesting that hats are under-utilized. Students from non-government (private schools were twice as likely as students from government schools to wear a hat (41% vs 18.2% p=0.003. Neither the hat nor the shirt-wearing behaviors of student spectators were significantly influenced by their school’s size (number of students, educational advantage, sun-protection policy score or SunSmart status, indicating that other socio-economic factors, not assessed here, may have influenced the results. Our findings suggest that the mandatory swim-shirt policy introduced in 2008 was very effective, especially initially. However, monitoring and feedback of results to schools may be needed to maintain high levels of compliance in the longer-term. Schoolchildren attending swimming carnivals should not rely on sunscreen or shade alone to protect against direct and reflected-sunlight, and need prompting to put a hat and shirt back on immediately after

  2. Bacterial natural transformation by highly fragmented and damaged DNA

    DEFF Research Database (Denmark)

    Overballe-Petersen, Søren; Harms, Klaus; Orlando, Ludovic Antoine Alexandre

    2013-01-01

    for microbes, but not as potential substrate for bacterial evolution. Here, we show that fragmented DNA molecules (≥20 bp) that additionally may contain abasic sites, cross-links, or miscoding lesions are acquired by the environmental bacterium Acinetobacter baylyi through natural transformation. With uptake......DNA molecules are continuously released through decomposition of organic matter and are ubiquitous in most environments. Such DNA becomes fragmented and damaged (often DNA is recognized as nutrient source...... of DNA from a 43,000-y-old woolly mammoth bone, we further demonstrate that such natural transformation events include ancient DNA molecules. We find that the DNA recombination is RecA recombinase independent and is directly linked to DNA replication. We show that the adjacent nucleotide variations...

  3. Overview of ALICE results at Quark Matter 2014

    Energy Technology Data Exchange (ETDEWEB)

    Grosse-Oetringhaus, Jan Fiete

    2014-11-15

    The results released by the ALICE Collaboration at Quark Matter 2014 address topics from identified-particle jet fragmentation functions in pp collisions, to the search for collective signatures in p–Pb collisions to precision measurements of jet quenching with D mesons in Pb–Pb collisions. This paper gives an overview of the contributions (31 parallel talks, 2 flash talks and 80 posters) by the ALICE Collaboration at Quark Matter 2014.

  4. Branching ratios in sequential statistical multifragmentation

    International Nuclear Information System (INIS)

    Moretto, L.G.; Phair, L.; Tso, K.; Jing, K.; Wozniak, G.J.

    1995-01-01

    The energy dependence of the probability of producing n fragments follows a characteristic statistical law. Experimental intermediate-mass-fragment multiplicity distributions are shown to be binomial at all excitation energies. From these distributions a single binary event probability can be extracted that has the thermal dependence p=exp[-B/T]. Thus, it is inferred that multifragmentation is a sequence of thermal binary events. The increase of p with excitation energy implies a corresponding contraction of the time-scale and explains recently observed fragment-fragment and fragment-spectator Coulomb correlations. (authors). 22 refs., 5 figs

  5. Branching ratios in sequential statistical multifragmentation

    International Nuclear Information System (INIS)

    Moretto, L.G.; Phair, L.; Tso, K.; Jing, K.; Wozniak, G.J.

    1995-01-01

    The energy dependence of the probability of producing n fragments follows a characteristic statistical law. Experimental intermediate-mass-fragment multiplicity distributions are shown to be binomial at all excitation energies. From these distributions a single binary event probability can be extracted that has the thermal dependence p = exp[-B/T]. Thus, it is inferred that multifragmentation is a sequence of thermal binary events. The increase of p with excitation energy implies a corresponding contraction of the time-scale and explains recently observed fragment-fragment and fragment-spectator Coulomb correlations. (author). 22 refs., 5 figs

  6. Research on critical behaviour during fragmentation of the projectile in the Xe+Sn (at 50 MeV/A) reaction; Recherche d`un comportement critique dans la fragmentation du projectile dans la reaction Xe+Sn a 50 MeV/A

    Energy Technology Data Exchange (ETDEWEB)

    Benlliure, J

    1995-03-01

    The study of moments of fragments charge distributions produced in heavy ions collisions can give us evidence of a critical behavior of nuclear matter which could explain the multifragmentation pattern. From an experimental point of view, in order to perform this capabilities of the INDRA detector has made it possible to identify all these particles and to reconstruct the initial projectile-like fragment coming from binary collisions in the reaction Xe+Sn at 50 MeV/A. We have selected events where the initial projectile-like fragments keep their entire charge in a large range of excitation energy. The study of these fragment`s characteristics show clearly a change in the deexcitation pattern. The evolution of moments of the fragment charge distributions has been reproduced within a percolation model, in this sense we can interpreter this change in the deexcitation pattern as a function of the initial projectile-like fragment`s size shows the existence of finite-size effects. However, the signature of a phase transition remains independent on the projectile-like fragment`s size. (author). 74 refs., 58 figs., 9 tabs.

  7. Virtual fragment preparation for computational fragment-based drug design.

    Science.gov (United States)

    Ludington, Jennifer L

    2015-01-01

    Fragment-based drug design (FBDD) has become an important component of the drug discovery process. The use of fragments can accelerate both the search for a hit molecule and the development of that hit into a lead molecule for clinical testing. In addition to experimental methodologies for FBDD such as NMR and X-ray Crystallography screens, computational techniques are playing an increasingly important role. The success of the computational simulations is due in large part to how the database of virtual fragments is prepared. In order to prepare the fragments appropriately it is necessary to understand how FBDD differs from other approaches and the issues inherent in building up molecules from smaller fragment pieces. The ultimate goal of these calculations is to link two or more simulated fragments into a molecule that has an experimental binding affinity consistent with the additive predicted binding affinities of the virtual fragments. Computationally predicting binding affinities is a complex process, with many opportunities for introducing error. Therefore, care should be taken with the fragment preparation procedure to avoid introducing additional inaccuracies.This chapter is focused on the preparation process used to create a virtual fragment database. Several key issues of fragment preparation which affect the accuracy of binding affinity predictions are discussed. The first issue is the selection of the two-dimensional atomic structure of the virtual fragment. Although the particular usage of the fragment can affect this choice (i.e., whether the fragment will be used for calibration, binding site characterization, hit identification, or lead optimization), general factors such as synthetic accessibility, size, and flexibility are major considerations in selecting the 2D structure. Other aspects of preparing the virtual fragments for simulation are the generation of three-dimensional conformations and the assignment of the associated atomic point charges.

  8. Excess Substrate is a Spectator Ligand in a Rhodium-Catalyzed Asymmetric [2+2+2] Cycloaddition of Alkenyl Isocyanates with Tolanes

    Science.gov (United States)

    Oinen, Mark Emil; Yu, Robert T.; Rovis, Tomislav

    2009-01-01

    Excess substrate has been identified as an unintended spectator ligand affecting enantioselectivity in the [2+2+2] cycloaddition of alkenyl isocyanates with tolanes. Replacement of excess substrate with an exogenous additive affords products with consistent and higher ee’s. The increase in enantioselectivity is the result of a change in composition of a proposed rhodium(III) intermediate on the catalytic cycle. The net result is a rational probe of a short-lived rhodium(III) intermediate, and gives insight that may have applications in many rhodium catalyzed reactions. PMID:19803471

  9. Dynamic and Implications of Football Fans' Club and Fans ...

    African Journals Online (AJOL)

    DrNneka

    As spectator in football game for example, human beings are known to fragment into fans groups. ..... since respondents identified performance as the main motivating factor in their selection of supporting teams ... directional. They are supports ...

  10. Statistical and off-equilibrium production of fragments in heavy ion collisions at intermediate energies; Production statistique et hors-equilibre de fragments dans les collisions d`ions lourdes aux energies intermediaires

    Energy Technology Data Exchange (ETDEWEB)

    Bocage, Frederic [Lab. de Physique Corpusculaire, Caen Univ., 14 - Caen (France)

    1998-12-15

    The study of reaction products, fragments and light charged particles, emitted during heavy-ion collisions at intermediate energies has shown the dominant binary dissipative character of the reaction, which is persisting for almost all impact parameters. However, in comparison with this purely binary process, an excess of nuclear matter is observed in-between the quasi-projectile and the quasi-target. To understand the mechanisms producing such an excess, this work studies more precisely the breakup in two fragments of the quasi-projectile formed in Xe+Sn, from 25 to 50 MeV/u, and Gd+C and Gd+U at 36 MeV/u. The data were obtained during the first INDRA experiment at GANIL. The angular distributions of the two fragments show the competition between statistical fission and non-equilibrated breakup of the quasi-projectile. In the second case, the two fragments are aligned along the separation axis of the two primary partners. The comparison of the fission directions and probabilities with statistical models allows us to measure the fission time, as well as the angular momentum, temperature and size of the fissioning residue. The relative velocities are compatible with Coulomb and thermal effects in the case of statistical fission and are found much higher for the breakup of a non-equilibrated quasi-projectile, which indicates that the projectile was deformed during interaction with the target. Such deformations should be compared with dynamical calculations in order to constrain the viscosity of nuclear matter and the parameters of the nucleon-nucleon interaction, (author) 148 refs., 77 figs., 11 tabs.

  11. Multi-particle correlation observables in high energy nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Stock, R.

    1981-01-01

    Global features of exclusively measured events, including number correlations and vector correlations, and hybrid analysis of measurements of one or two specific fragments like spectator nuclei, high transverse momentum particles, polarization of one particle, etc., are considered

  12. Multiplicity correlations of intermediate-mass fragments with pions and fast protons in 12C + 197AU

    International Nuclear Information System (INIS)

    Turzo, K.; Begemann-Blaich, M.L.; Auger, G.

    2003-12-01

    Low-energy π + (E π 12 C+ 197 Au collisions at incident energies from 300 to 1800 MeV per nucleon were detected with the Si-Si(Li)-CsI(Tl) calibration telescopes of the INDRA multidetector. The inclusive angular distributions are approximately isotropic, consistent with multiple rescattering in the target spectator. The multiplicity correlations of the low-energy pions and of energetic protons (E p >or ≤ 150 MeV) with intermediate-mass fragments were determined from the measured coincidence data. The deduced correlation functions 1 + R ∼ 1.3 for inclusive event samples reflect the strong correlations evident from the common impact-parameter dependence of the considered multiplicities. For narrow impact-parameter bins (based on charged-particle multiplicity), the correlation functions are close to unity and do not indicate strong additional correlations. Only for pions at high particle multiplicities (central collisions) a weak anticorrelation is observed, probably due to a limited competition between these emissions. Overall, the results are consistent with the equilibrium assumption made in statistical multifragmentation scenarios. Predictions obtained with intranuclear cascade models coupled to the statistical multifragmentation model are in good agreement with the experimental data. (orig.)

  13. Fragmentation analysis of water-soluble atmospheric organic matter using ultrahigh-resolution FT-ICR mass spectrometry.

    Science.gov (United States)

    Leclair, Jeffrey P; Collett, Jeffrey L; Mazzoleni, Lynn R

    2012-04-17

    Isolated water-soluble atmospheric organic matter (AOM) analytes extracted from radiation fogwater samples were analyzed using collision induced dissociation with ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Tandem mass analysis was performed on several mass ranges between 100 and 400 Da to characterize the functional groups of AOM species. Compounds containing nitrogen and/or sulfur were targeted because of the high number of oxygen atoms contained in their molecular formulas. Due to the large number of isobaric ions in the precursor isolation ranges, large numbers of product ions resulted from collision induced dissociation. Common neutral losses were assigned by matching the molecular formulas of the expected product ions with the detected product ions within the appropriate mass spectra. Since polar functional groups are expected to affect the hygroscopic properties of aerosols, the losses of H(2)O, CO(2), CH(3)OH, HNO(3), CH(3)NO(3), SO(3), SO(4) and combinations of these were specifically targeted. Among the 421 compounds studied, the most frequently observed neutral losses were CO(2) (54%), H(2)O (43%) and CH(3)OH (40%). HNO(3) losses were observed for 63% of the studied nitrogen containing compounds and 33% of the studied compounds containing both nitrogen and sulfur. SO(3) losses were observed for 85% of the studied sulfur containing compounds and 42% of studied compounds containing both nitrogen and sulfur. A number of molecular formulas matching those of monoterpene ozonolysis SOA were observed; they include organonitrates, organosulfates, and nitroxy-organosulfates. Overall, the results of fragmentation analysis of 400+ individual molecular precursors elucidate the complexity and multifunctional nature of the isolated water-soluble AOM.

  14. Jet fragmentation

    International Nuclear Information System (INIS)

    Saxon, D.H.

    1985-10-01

    The paper reviews studies on jet fragmentation. The subject is discussed under the topic headings: fragmentation models, charged particle multiplicity, bose-einstein correlations, identified hadrons in jets, heavy quark fragmentation, baryon production, gluon and quark jets compared, the string effect, and two successful models. (U.K.)

  15. On Fragments and Geometry : The International Legal Order as Metaphor and How It Matters

    NARCIS (Netherlands)

    N.M. Rajkovic (Nikolas)

    2013-01-01

    markdownabstract__Abstract__ This article engages the narrative of fragmentation in international law by asserting that legal academics and professionals have failed to probe more deeply into ‘fragmentation’ as a concept and, more specifically, as a spatial metaphor. The contention here is that

  16. Missing Fragments: Detecting Cooperative Binding in Fragment-Based Drug Design

    Science.gov (United States)

    2012-01-01

    The aim of fragment-based drug design (FBDD) is to identify molecular fragments that bind to alternate subsites within a given binding pocket leading to cooperative binding when linked. In this study, the binding of fragments to human phenylethanolamine N-methyltransferase is used to illustrate how (a) current protocols may fail to detect fragments that bind cooperatively, (b) theoretical approaches can be used to validate potential hits, and (c) apparent false positives obtained when screening against cocktails of fragments may in fact indicate promising leads. PMID:24900472

  17. Novel two-step laser ablation and ionization mass spectrometry (2S-LAIMS) of actor-spectator ice layers: Probing chemical composition of D2O ice beneath a H2O ice layer

    International Nuclear Information System (INIS)

    Yang, Rui; Gudipati, Murthy S.

    2014-01-01

    In this work, we report for the first time successful analysis of organic aromatic analytes imbedded in D 2 O ices by novel infrared (IR) laser ablation of a layered non-absorbing D 2 O ice (spectator) containing the analytes and an ablation-active IR-absorbing H 2 O ice layer (actor) without the analyte. With these studies we have opened up a new method for the in situ analysis of solids containing analytes when covered with an IR laser-absorbing layer that can be resonantly ablated. This soft ejection method takes advantage of the tenability of two-step infrared laser ablation and ultraviolet laser ionization mass spectrometry, previously demonstrated in this lab to study chemical reactions of polycyclic aromatic hydrocarbons (PAHs) in cryogenic ices. The IR laser pulse tuned to resonantly excite only the upper H 2 O ice layer (actor) generates a shockwave upon impact. This shockwave penetrates the lower analyte-containing D 2 O ice layer (spectator, a non-absorbing ice that cannot be ablated directly with the wavelength of the IR laser employed) and is reflected back, ejecting the contents of the D 2 O layer into the vacuum where they are intersected by a UV laser for ionization and detection by a time-of-flight mass spectrometer. Thus, energy is transmitted from the laser-absorbing actor layer into the non-absorbing spectator layer resulting its ablation. We found that isotope cross-contamination between layers was negligible. We also did not see any evidence for thermal or collisional chemistry of PAH molecules with H 2 O molecules in the shockwave. We call this “shockwave mediated surface resonance enhanced subsurface ablation” technique as “two-step laser ablation and ionization mass spectrometry of actor-spectator ice layers.” This method has its roots in the well-established MALDI (matrix assisted laser desorption and ionization) method. Our method offers more flexibility to optimize both the processes—ablation and ionization. This new technique

  18. Molecular dynamics for dense matter

    International Nuclear Information System (INIS)

    Maruyama, Toshiki; Chiba, Satoshi; Watanabe, Gentaro

    2012-01-01

    We review a molecular dynamics method for nucleon many-body systems called quantum molecular dynamics (QMD), and our studies using this method. These studies address the structure and the dynamics of nuclear matter relevant to neutron star crusts, supernova cores, and heavy-ion collisions. A key advantage of QMD is that we can study dynamical processes of nucleon many-body systems without any assumptions about the nuclear structure. First, we focus on the inhomogeneous structures of low-density nuclear matter consisting not only of spherical nuclei but also of nuclear “pasta”, i.e., rod-like and slab-like nuclei. We show that pasta phases can appear in the ground and equilibrium states of nuclear matter without assuming nuclear shape. Next, we show our simulation of compression of nuclear matter which corresponds to the collapsing stage of supernovae. With the increase in density, a crystalline solid of spherical nuclei changes to a triangular lattice of rods by connecting neighboring nuclei. Finally, we discuss fragment formation in expanding nuclear matter. Our results suggest that a generally accepted scenario based on the liquid–gas phase transition is not plausible at lower temperatures. (author)

  19. Molecular dynamics for dense matter

    Science.gov (United States)

    Maruyama, Toshiki; Watanabe, Gentaro; Chiba, Satoshi

    2012-08-01

    We review a molecular dynamics method for nucleon many-body systems called quantum molecular dynamics (QMD), and our studies using this method. These studies address the structure and the dynamics of nuclear matter relevant to neutron star crusts, supernova cores, and heavy-ion collisions. A key advantage of QMD is that we can study dynamical processes of nucleon many-body systems without any assumptions about the nuclear structure. First, we focus on the inhomogeneous structures of low-density nuclear matter consisting not only of spherical nuclei but also of nuclear "pasta", i.e., rod-like and slab-like nuclei. We show that pasta phases can appear in the ground and equilibrium states of nuclear matter without assuming nuclear shape. Next, we show our simulation of compression of nuclear matter which corresponds to the collapsing stage of supernovae. With the increase in density, a crystalline solid of spherical nuclei changes to a triangular lattice of rods by connecting neighboring nuclei. Finally, we discuss fragment formation in expanding nuclear matter. Our results suggest that a generally accepted scenario based on the liquid-gas phase transition is not plausible at lower temperatures.

  20. Composition of structural fragments and the mineralization rate of organic matter in zonal soils

    Science.gov (United States)

    Larionova, A. A.; Zolotareva, B. N.; Kolyagin, Yu. G.; Kvitkina, A. K.; Kaganov, V. V.; Kudeyarov, V. N.

    2015-10-01

    Comparative analysis of the climatic characteristics and the recalcitrance against decomposition of organic matter in the zonal soil series of European Russia, from peat surface-gley tundra soil to brown semidesert soil, has assessed the relationships between the period of biological activity, the content of chemically stable functional groups, and the mineralization of humus. The stability of organic matter has been determined from the ratio of functional groups using the solid-state 13C NMR spectroscopy of soil samples and the direct measurements of organic matter mineralization from CO2 emission. A statistically significant correlation has been found between the period of biological activity and the humification indices: the CHA/CFA ratio, the aromaticity, and the alkyl/ O-alkyl ratio in organic matter. The closest correlation has been observed between the period of biological activity and the alkyl/ O-alkyl ratio; therefore, this parameter can be an important indicator of the soil humus status. A poor correlation between the mineralization rate and the content of chemically stable functional groups in soil organic matter has been revealed for the studied soil series. At the same time, the lowest rate of carbon mineralization has been observed in southern chernozem characterized by the maximum content of aromatic groups (21% Corg) and surface-gley peat tundra soil, where an extremely high content of unsubstituted CH2 and CH3 alkyl groups (41% Corg) has been noted.

  1. Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics

    Science.gov (United States)

    Lau, Wan F.; Withka, Jane M.; Hepworth, David; Magee, Thomas V.; Du, Yuhua J.; Bakken, Gregory A.; Miller, Michael D.; Hendsch, Zachary S.; Thanabal, Venkataraman; Kolodziej, Steve A.; Xing, Li; Hu, Qiyue; Narasimhan, Lakshmi S.; Love, Robert; Charlton, Maura E.; Hughes, Samantha; van Hoorn, Willem P.; Mills, James E.

    2011-07-01

    Fragment Based Drug Discovery (FBDD) continues to advance as an efficient and alternative screening paradigm for the identification and optimization of novel chemical matter. To enable FBDD across a wide range of pharmaceutical targets, a fragment screening library is required to be chemically diverse and synthetically expandable to enable critical decision making for chemical follow-up and assessing new target druggability. In this manuscript, the Pfizer fragment library design strategy which utilized multiple and orthogonal metrics to incorporate structure, pharmacophore and pharmacological space diversity is described. Appropriate measures of molecular complexity were also employed to maximize the probability of detection of fragment hits using a variety of biophysical and biochemical screening methods. In addition, structural integrity, purity, solubility, fragment and analog availability as well as cost were important considerations in the selection process. Preliminary analysis of primary screening results for 13 targets using NMR Saturation Transfer Difference (STD) indicates the identification of uM-mM hits and the uniqueness of hits at weak binding affinities for these targets.

  2. Correlations of intermediate mass fragments from Fe+Ta, Au, and Th collisions

    International Nuclear Information System (INIS)

    Sangster, T.C.; Begemann-Blaich, M.; Blaich, T.; Britt, H.C.; Hansen, L.F.; Namboodiri, M.N.; Peilert, G.

    1995-01-01

    Charge, velocity, and angular correlations between intermediate mass fragments (IMF) are presented for 50 and 100 MeV/nucleon Fe bombardments of Ta, Au, and Th targets. Correlation functions generated as a function of the relative velocity and the opening angle between two IMF's are qualitatively independent of the projectile energy and target mass and show a suppression at small relative velocities and opening angles due to the Coulomb repulsion between the fragments. The correlations are consistent with IMF's emitted primarily from a highly excited target residue following a rapid preequilibrium cascade. The correlation data are compared to model calculations using the event generator MENEKA and the quantum molecular dynamics (QMD) code with a statistical deexcitation of residual fragments utilizing the multifragmentation code SMM. All data are consistent with a simultaneous multifragmentation at a freeze-out density of 0.1--0.3 times normal nuclear matter density or a more sequential emission with time constant τ≤500 fm/c

  3. The dark matter of galaxy voids

    Science.gov (United States)

    Sutter, P. M.; Lavaux, Guilhem; Wandelt, Benjamin D.; Weinberg, David H.; Warren, Michael S.

    2014-03-01

    How do observed voids relate to the underlying dark matter distribution? To examine the spatial distribution of dark matter contained within voids identified in galaxy surveys, we apply Halo Occupation Distribution models representing sparsely and densely sampled galaxy surveys to a high-resolution N-body simulation. We compare these galaxy voids to voids found in the halo distribution, low-resolution dark matter and high-resolution dark matter. We find that voids at all scales in densely sampled surveys - and medium- to large-scale voids in sparse surveys - trace the same underdensities as dark matter, but they are larger in radius by ˜20 per cent, they have somewhat shallower density profiles and they have centres offset by ˜ 0.4Rv rms. However, in void-to-void comparison we find that shape estimators are less robust to sampling, and the largest voids in sparsely sampled surveys suffer fragmentation at their edges. We find that voids in galaxy surveys always correspond to underdensities in the dark matter, though the centres may be offset. When this offset is taken into account, we recover almost identical radial density profiles between galaxies and dark matter. All mock catalogues used in this work are available at http://www.cosmicvoids.net.

  4. Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library.

    Science.gov (United States)

    Huschmann, Franziska U; Linnik, Janina; Sparta, Karine; Ühlein, Monika; Wang, Xiaojie; Metz, Alexander; Schiebel, Johannes; Heine, Andreas; Klebe, Gerhard; Weiss, Manfred S; Mueller, Uwe

    2016-05-01

    Crystallographic screening of the binding of small organic compounds (termed fragments) to proteins is increasingly important for medicinal chemistry-oriented drug discovery. To enable such experiments in a widespread manner, an affordable 96-compound library has been assembled for fragment screening in both academia and industry. The library is selected from already existing protein-ligand structures and is characterized by a broad ligand diversity, including buffer ingredients, carbohydrates, nucleotides, amino acids, peptide-like fragments and various drug-like organic compounds. When applied to the model protease endothiapepsin in a crystallographic screening experiment, a hit rate of nearly 10% was obtained. In comparison to other fragment libraries and considering that no pre-screening was performed, this hit rate is remarkably high. This demonstrates the general suitability of the selected compounds for an initial fragment-screening campaign. The library composition, experimental considerations and time requirements for a complete crystallographic fragment-screening campaign are discussed as well as the nine fully refined obtained endothiapepsin-fragment structures. While most of the fragments bind close to the catalytic centre of endothiapepsin in poses that have been observed previously, two fragments address new sites on the protein surface. ITC measurements show that the fragments bind to endothiapepsin with millimolar affinity.

  5. Structures of endothiapepsin–fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library

    Science.gov (United States)

    Huschmann, Franziska U.; Linnik, Janina; Sparta, Karine; Ühlein, Monika; Wang, Xiaojie; Metz, Alexander; Schiebel, Johannes; Heine, Andreas; Klebe, Gerhard; Weiss, Manfred S.; Mueller, Uwe

    2016-01-01

    Crystallographic screening of the binding of small organic compounds (termed fragments) to proteins is increasingly important for medicinal chemistry-oriented drug discovery. To enable such experiments in a widespread manner, an affordable 96-compound library has been assembled for fragment screening in both academia and industry. The library is selected from already existing protein–ligand structures and is characterized by a broad ligand diversity, including buffer ingredients, carbohydrates, nucleotides, amino acids, peptide-like fragments and various drug-like organic compounds. When applied to the model protease endothiapepsin in a crystallographic screening experiment, a hit rate of nearly 10% was obtained. In comparison to other fragment libraries and considering that no pre-screening was performed, this hit rate is remarkably high. This demonstrates the general suitability of the selected compounds for an initial fragment-screening campaign. The library composition, experimental considerations and time requirements for a complete crystallographic fragment-screening campaign are discussed as well as the nine fully refined obtained endothiapepsin–fragment structures. While most of the fragments bind close to the catalytic centre of endothiapepsin in poses that have been observed previously, two fragments address new sites on the protein surface. ITC measurements show that the fragments bind to endothiapepsin with millimolar affinity. PMID:27139825

  6. Towards a population synthesis model of self-gravitating disc fragmentation and tidal downsizing II: the effect of fragment-fragment interactions

    Science.gov (United States)

    Forgan, D. H.; Hall, C.; Meru, F.; Rice, W. K. M.

    2018-03-01

    It is likely that most protostellar systems undergo a brief phase where the protostellar disc is self-gravitating. If these discs are prone to fragmentation, then they are able to rapidly form objects that are initially of several Jupiter masses and larger. The fate of these disc fragments (and the fate of planetary bodies formed afterwards via core accretion) depends sensitively not only on the fragment's interaction with the disc, but also with its neighbouring fragments. We return to and revise our population synthesis model of self-gravitating disc fragmentation and tidal downsizing. Amongst other improvements, the model now directly incorporates fragment-fragment interactions while the disc is still present. We find that fragment-fragment scattering dominates the orbital evolution, even when we enforce rapid migration and inefficient gap formation. Compared to our previous model, we see a small increase in the number of terrestrial-type objects being formed, although their survival under tidal evolution is at best unclear. We also see evidence for disrupted fragments with evolved grain populations - this is circumstantial evidence for the formation of planetesimal belts, a phenomenon not seen in runs where fragment-fragment interactions are ignored. In spite of intense dynamical evolution, our population is dominated by massive giant planets and brown dwarfs at large semimajor axis, which direct imaging surveys should, but only rarely, detect. Finally, disc fragmentation is shown to be an efficient manufacturer of free-floating planetary mass objects, and the typical multiplicity of systems formed via gravitational instability will be low.

  7. Hadronic matter in collision: Proceedings of the second international workshop on local equilibrium in strong interaction physics

    International Nuclear Information System (INIS)

    Carruthers, P.; Stottman, D.

    1986-01-01

    This book contains papers given at a conference on hadronic matter in collision. Some of the topics include the following: Nuclear Fragmentation; Nucleus-Nucleus Reactions; Phase Transformations; Hydrodynamics of Nuclear Matter; Hadron Hadronic Multi-Particle Production; and Bose Einstien Correlations

  8. Covariant Spectator Theory of heavy–light and heavy mesons and the predictive power of covariant interaction kernels

    Energy Technology Data Exchange (ETDEWEB)

    Leitão, Sofia, E-mail: sofia.leitao@tecnico.ulisboa.pt [CFTP, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal); Stadler, Alfred, E-mail: stadler@uevora.pt [Departamento de Física, Universidade de Évora, 7000-671 Évora (Portugal); CFTP, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal); Peña, M.T., E-mail: teresa.pena@tecnico.ulisboa.pt [Departamento de Física, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal); CFTP, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal); Biernat, Elmar P., E-mail: elmar.biernat@tecnico.ulisboa.pt [CFTP, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal)

    2017-01-10

    The Covariant Spectator Theory (CST) is used to calculate the mass spectrum and vertex functions of heavy–light and heavy mesons in Minkowski space. The covariant kernel contains Lorentz scalar, pseudoscalar, and vector contributions. The numerical calculations are performed in momentum space, where special care is taken to treat the strong singularities present in the confining kernel. The observed meson spectrum is very well reproduced after fitting a small number of model parameters. Remarkably, a fit to a few pseudoscalar meson states only, which are insensitive to spin–orbit and tensor forces and do not allow to separate the spin–spin from the central interaction, leads to essentially the same model parameters as a more general fit. This demonstrates that the covariance of the chosen interaction kernel is responsible for the very accurate prediction of the spin-dependent quark–antiquark interactions.

  9. Universal elements of fragmentation

    International Nuclear Information System (INIS)

    Yanovsky, V. V.; Tur, A. V.; Kuklina, O. V.

    2010-01-01

    A fragmentation theory is proposed that explains the universal asymptotic behavior of the fragment-size distribution in the large-size range, based on simple physical principles. The basic principles of the theory are the total mass conservation in a fragmentation process and a balance condition for the energy expended in increasing the surface of fragments during their breakup. A flux-based approach is used that makes it possible to supplement the basic principles and develop a minimal theory of fragmentation. Such a supplementary principle is that of decreasing fragment-volume flux with increasing energy expended in fragmentation. It is shown that the behavior of the decreasing flux is directly related to the form of a power-law fragment-size distribution. The minimal theory is used to find universal asymptotic fragment-size distributions and to develop a natural physical classification of fragmentation models. A more general, nonlinear theory of strong fragmentation is also developed. It is demonstrated that solutions to a nonlinear kinetic equation consistent with both basic principles approach a universal asymptotic size distribution. Agreement between the predicted asymptotic fragment-size distributions and experimental observations is discussed.

  10. Strong and nonlinear effects of fragmentation on ecosystem service provision at multiple scales

    Science.gov (United States)

    Mitchell, Matthew G. E.; Bennett, Elena M.; Gonzalez, Andrew

    2015-09-01

    Human actions, such as converting natural land cover to agricultural or urban land, result in the loss and fragmentation of natural habitat, with important consequences for the provision of ecosystem services. Such habitat loss is especially important for services that are supplied by fragments of natural land cover and that depend on flows of organisms, matter, or people across the landscape to produce benefits, such as pollination, pest regulation, recreation and cultural services. However, our quantitative knowledge about precisely how different patterns of landscape fragmentation might affect the provision of these types of services is limited. We used a simple, spatially explicit model to evaluate the potential impact of natural land cover loss and fragmentation on the provision of hypothetical ecosystem services. Based on current literature, we assumed that fragments of natural land cover provide ecosystem services to the area surrounding them in a distance-dependent manner such that ecosystem service flow depended on proximity to fragments. We modeled seven different patterns of natural land cover loss across landscapes that varied in the overall level of landscape fragmentation. Our model predicts that natural land cover loss will have strong and unimodal effects on ecosystem service provision, with clear thresholds indicating rapid loss of service provision beyond critical levels of natural land cover loss. It also predicts the presence of a tradeoff between maximizing ecosystem service provision and conserving natural land cover, and a mismatch between ecosystem service provision at landscape versus finer spatial scales. Importantly, the pattern of landscape fragmentation mitigated or intensified these tradeoffs and mismatches. Our model suggests that managing patterns of natural land cover loss and fragmentation could help influence the provision of multiple ecosystem services and manage tradeoffs and synergies between services across different human

  11. Heavy ion physics at the Brookhaven alternating gradient synchrotron

    International Nuclear Information System (INIS)

    Sangster, T.C.

    1995-01-01

    The collision of large nuclei at relativisitic energies is the only known mechanism for creating and studying the properties (equation-of-state, EOS) of extremely dense nuclear matter. At sufficiently high matter densities, one of the most exciting possibilities is the formation of a Quark Gluon Plasma (QGP). However, it is an extremely difficult task to determine the ultimate density achieved during these collisions due to the fleeting nature of the high density state (the lifetime of these states is typically a few times 10-24 ns). We must rely on detailed comparisons between experimental measurements and complex Monte Carlo simulations of the colliding nuclei in order to extract meaningful estimates of the nuclear matter EOS. Our approach has been to study the behavior of the spectator matter (those protons and neutrons which do not directly interact during the collision) to determine the dynamics of the high density state which must necessarily influence the spectator matter as it decays. This report summarizes some of the key results of our study

  12. Unstable gravitino dark matter and neutrino flux

    International Nuclear Information System (INIS)

    Covi, L.; Grefe, M.; Ibarra, A.; Tran, D.

    2008-09-01

    The gravitino is a promising supersymmetric dark matter candidate which does not require exact R-parity conservation. In fact, even with some small R-parity breaking, gravitinos are sufficiently long-lived to constitute the dark matter of the Universe, while yielding a cosmological scenario consistent with primordial nucleosynthesis and the high reheating temperature required for thermal leptogenesis. In this paper, we compute the neutrino flux from direct gravitino decay and gauge boson fragmentation in a simple scenario with bilinear R-parity breaking. Our choice of parameters is motivated by a proposed interpretation of anomalies in the extragalactic gamma-ray spectrum and the positron fraction in terms of gravitino dark matter decay. We find that the generated neutrino flux is compatible with present measurements. We also discuss the possibility of detecting these neutrinos in present and future experiments and conclude that it is a challenging task. However, if detected, this distinctive signal might bring significant support to the scenario of gravitinos as decaying dark matter. (orig.)

  13. Identifying core, exciting, and hybrid attributes in fans' assessments of major (World Cup) spectator sports events.

    Science.gov (United States)

    Gau, Li-Shiue

    2013-12-01

    This paper adopts a methodology of asymmetrical analyses to investigate the relevant importance of spectator sport attributes in terms of their non-linear associations with the benefits that fans experience while watching sports. Questionnaires tapping 16 attributes (e.g., teamwork, sportsmanship, level of competition) and 16 benefits (e.g., good mood, exciting experience, support for my favorite team) were distributed to a sample of fans at the outdoor broadcast of the 2010 World Cup final game at the National Stadium in Kaohsiung, Taiwan. 427 participants rated the importance and benefit of each attribute experienced from watching the game. Attributes were categorized as core, exciting, or hybrid attributes. The star player was the core attribute; rivalry, popularity, and coach were the exciting attributes; and the other 12 attributes were hybrid. Two-dimensional space analyses showed that attributes "sportsmanship, teamwork, and supporting a team" were both explicitly and implicitly important attributes. The methodology of asymmetrical analyses can help managers prioritize the focus of attributes and allocate resources effectively.

  14. Controlled fragmentation

    International Nuclear Information System (INIS)

    Arnold, Werner

    2002-01-01

    Contrary to natural fragmentation, controlled fragmentation offers the possibility to adapt fragment parameters like size and mass to the performance requirements in a very flexible way. Known mechanisms like grooves inside the casing, weaken the structure. This is, however, excluded for applications with high accelerations during launch or piercing requirements for example on a semi armor piercing penetrator. Another method to achieve controlled fragmentation with an additional grid layer is presented with which the required grooves are produced 'just in time' inside the casing during detonation of the high explosive. The process of generating the grooves aided by the grid layer was studied using the hydrocode HULL with respect to varying grid designs and material combinations. Subsequent to this, a large range of these theoretically investigated combinations was contemplated in substantial experimental tests. With an optimised grid design and a suitable material selection, the controlled fragment admits a very flexible adaptation to the set requirements. Additional advantages like the increase of perforation performance or incendiary amplification can be realized with the grid layer

  15. Flow of nucleons and fragments in 40Ar+27Al collisions studied with antisymmetrized molecular dynamics

    International Nuclear Information System (INIS)

    Ono, A.; Horiuchi, H.

    1995-01-01

    Collective transverse momentum flow of nucleons and fragments in intermediate energy 40 Ar+ 27 Al collisions is calculated with the antisymmetrized molecular dynamics (AMD). The observed flow and its balance energy are reproduced well by calculation with the Gogny force which corresponds to the soft equation of state (EOS) of nuclear matter. The calculated absolute value of the fragment flow is larger than that of the nucleon flow in the negative flow region, which can be explained by the existence of two components of flow. In addition to many similarities, the difference in the deuteron flow is found between 12 C+ 12 C and 40 Ar+ 27 Al collisions, and its origin is investigated by studying the production mechanism of light fragments. We also investigate the dependence of the flow of nucleons and fragments on the stochastic collision cross section and the effective interaction, and conclude that the stiff EOS without momentum dependence of the mean field is not consistent with the experimental data

  16. Fragmentation cross sections outside the limiting-fragmentation regime

    CERN Document Server

    Sümmerer, K

    2003-01-01

    The empirical parametrization of fragmentation cross sections, EPAX, has been successfully applied to estimate fragment production cross sections in reactions of heavy ions at high incident energies. It is checked whether a similar parametrization can be found for proton-induced spallation around 1 GeV, the range of interest for ISOL-type RIB facilities. The validity of EPAX for medium-energy heavy-ion induced reactions is also checked. Only a few datasets are available, but in general EPAX predicts the cross sections rather well, except for fragments close to the projectile, where the experimental cross sections are found to be larger.

  17. Universality of fragment shapes.

    Science.gov (United States)

    Domokos, Gábor; Kun, Ferenc; Sipos, András Árpád; Szabó, Tímea

    2015-03-16

    The shape of fragments generated by the breakup of solids is central to a wide variety of problems ranging from the geomorphic evolution of boulders to the accumulation of space debris orbiting Earth. Although the statistics of the mass of fragments has been found to show a universal scaling behavior, the comprehensive characterization of fragment shapes still remained a fundamental challenge. We performed a thorough experimental study of the problem fragmenting various types of materials by slowly proceeding weathering and by rapid breakup due to explosion and hammering. We demonstrate that the shape of fragments obeys an astonishing universality having the same generic evolution with the fragment size irrespective of materials details and loading conditions. There exists a cutoff size below which fragments have an isotropic shape, however, as the size increases an exponential convergence is obtained to a unique elongated form. We show that a discrete stochastic model of fragmentation reproduces both the size and shape of fragments tuning only a single parameter which strengthens the general validity of the scaling laws. The dependence of the probability of the crack plan orientation on the linear extension of fragments proved to be essential for the shape selection mechanism.

  18. Anomalous nuclear fragments

    International Nuclear Information System (INIS)

    Karmanov, V.A.

    1983-01-01

    Experimental data are given, the status of anomalon problem is discussed, theoretical approaches to this problem are outlined. Anomalons are exotic objects formed following fragmentation of nuclei-targets under the effect of nuclei - a beam at the energy of several GeV/nucleon. These nuclear fragments have an anomalously large cross section of interaction and respectively, small free path, considerably shorter than primary nuclei have. The experimental daa are obtained in accelerators following irradiation of nuclear emulsions by 16 O, 56 Fe, 40 Ar beams, as well as propane by 12 C beams. The experimental data testify to dependence of fragment free path on the distance L from the point of the fragment formation. A decrease in the fragment free path is established more reliably than its dependence on L. The problem of the anomalon existence cannot be yet considered resolved. Theoretical models suggested for explanation of anomalously large cross sections of nuclear fragment interaction are variable and rather speculative

  19. Nuclear matter flow in the Kr+Au collisions at 43 MeV/u

    International Nuclear Information System (INIS)

    Bougault, R.; Delaunay, F.; Genoux-Lubain, A.; Lebrun, C.; Lecolley, J.F.; Lefebvres, F.; Louvel, M.; Steckmeyer, J.C.; Aloff, J.C.; Bilwes, B.; Bilwes, R.; Glaser, M.; Rudolf, G.; Scheibling, F.; Stuttge, L.

    1989-01-01

    When heavy nuclei collide at energy far above the Coulomb barrier we may study the property of nuclear matter in temperature and also density regions far away from the equilibrium. We then hope to study dynamical effects related to the compressibility and the two body collision term. At relativistic energies, some collective effects (flow, bounce off) have been established from a shape analysis done with a large number of light particles with Z ≤ 10. For incident energies lower than 100 MeV/u we may expect that the number of nuclear species formed will be smaller and that a large part of the nuclear matter involved in the collision will be shared in a limited number of heavy fragments (Z ≥ 10). If dynamical effects are still present at GANIL energies they ought to manifest themselves through the properties of the produced fragments (masses, emission angles, velocities and correlated variables). We will present an analysis of heavy nuclei collisions at 43 MeV/u based on as exclusive as possible detection of large fragments

  20. The Internet as Spectator Disclosure: Consent, Community, and Responsibility in Patricia Lockwood’s Viral Poem “Rape Joke”

    Directory of Open Access Journals (Sweden)

    Elizabeth Lanphier

    2016-10-01

    Full Text Available In “Rape as Spectator Sport and Creepshot Entertainment: Social Media and the Valorization of Lack of Consent,” the American philosopher Kelly Oliver provides a compelling and chilling analysis of the use and impact of social media by perpetrators of or bystanders to sexual assault. Patricia Lockwood’s 2013 long-form narrative poem, “Rape Joke,” which was published online and went viral on social media, offers a complement to Oliver’s analysis by presenting an Internet account of sexual assault from the survivor’s perspective. “Rape Joke,” through its content and form, raises questions to which we must philosophically and socially respond. These include both the importance of first-person narratives for social and philosophical engagements with trauma as well as the use of humor to constitute moral community and shape moral accountability.

  1. Use of a Minimally Invasive Retractor System for Retrieval of Intracranial Fragments in Wartime Trauma.

    Science.gov (United States)

    Rymarczuk, George N; Davidson, Laurence; Severson, Meryl A; Armonda, Rocco A

    2015-10-01

    Wartime penetrating brain injury can result in deep-seated parenchymal and intraventicular shrapnel, bullets, and bone. Large fragments pose a risk of secondary injury from migration, infection, and metal toxicity. It has been recommended that aggressive removal of fragments be avoided. The goal of this study is to report our technique of minimally invasive removal of select deep-seated fragments using a tubular retractor system. A retrospective review of our database of service members presenting with penetrating traumatic brain injuries incurred during Operations Iraqi Freedom and Enduring Freedom and treated at the Walter Reed Army Medical Center and the National Naval Medical Center was performed. Six individuals were identified in which the Vycor ViewSite retractor system (Vycor Medical, Boca Raton, Florida, USA) was used to remove a ventricular or deep intraparenchymal fragment. All patients were male and ranged in age from 21 to 29 years. Fragment location included the foramen of Monro; the atrium of the right lateral ventricle; parasagittally within the right occipital lobe; the occipital horn of the right lateral ventricle; the deep white matter of the dominant temporal lobe; and within the posterior right temporal lobe deep to the junction of the transverse and sigmoid dural venous sinuses. Fragments included in-driven bone, shrapnel from improvised explosive devices, and bullets. In all cases the fragment was successfully removed. No patient had worsening of their neurologic condition following surgery. Deep parenchymal and intraventricular fragments can be safely removed using a tubular retractor system. Published by Elsevier Inc.

  2. Heavy ion collisions

    International Nuclear Information System (INIS)

    Siemens, P.J.

    1979-12-01

    The status of research into collisions of nuclei at high energy is reviewed. Reactions and products are classified, and spectator matter is discussed. Then the thermalization of participant matter is considered at some length. Finally, disintegration of the hot matter is addressed. A = 20 and 40 projectiles of 250 to 1050 MeV/A are employed to illustrate the major points. 44 references, 10 figures

  3. Study of the shape of fragmentation events in central collisions

    International Nuclear Information System (INIS)

    Nguyen, A.D.; Durand, D.; Bocage, F.; Bougault, R.; Brou, R.; Colin, J; Cussol, D.; Genouin-Duhamel, E.; Gulminelli, F.; Lecolley, J.F.; Lefort, T.; Le Neindre, N.; Lopez, O.; Louvel, M.; Peter, J.; Steckmeyer, J.C.; Tamain, B.; Vient, E.

    1997-01-01

    The study of the most central collisions resulting in the fragmentation of nuclear systems requires a precise as highly possible knowledge of the space-time configuration of matter. Particularly, it is important to be able to define the event shapes in order to estimate the equilibrium degree reached by the system in the moment of its breakup. To do that, an tensor analysis was developed end applied to data from INDRA for the system Xe + Sn at 50 MeV/u. The obtained results were compared with the predictions of the SIMON generator. The analysis indicates a quasi-sphericity of the fragmentation source. This result is a convincing evidence in favor of formation of a highly excited system in equilibrium the life-time of which is long enough to relax the shape degrees of freedom as well as the internal freedom degrees. A comparison between the experimental results corresponding to the Xe + Sn central collisions at 50 MeV/u and the predictions of a SIMON calculation for different shapes of the fragmenting source is presented as a function of the variables D and C, which are linear combinations of the eigenvalues of the tensor of the moments used for characterisation of the event shape

  4. Collision induced fragmentation of fast molecular ions in solids and gases

    International Nuclear Information System (INIS)

    Gemmell, D.S.

    1979-01-01

    A brief review is given of recent high resolution measurements on fragments arising from the collision-induced dissociation of fast (MeV) molecular ions. For solid targets, strong wake effects are observed. For gaseous targets, excited electronic states of the projectile ions play an important role. Measurements of this type provide useful information on the charge states of fast ions traversing matter. The experimental techniques show promise as a unique method for determining the geometrical structures of the molecular-ion projectiles. 41 references

  5. Nuclear fragmentation

    International Nuclear Information System (INIS)

    Chung, K.C.

    1989-01-01

    An introduction to nuclear fragmentation, with emphasis in percolation ideas, is presented. The main theoretical models are discussed and as an application, the uniform expansion approximation is presented and the statistical multifragmentation model is used to calculate the fragment energy spectra. (L.C.)

  6. Active vs. spectator modes in nonadiabatic photodissociation dynamics of the hydroxymethyl radical via the 22A(3s) Rydberg state

    Science.gov (United States)

    Xie, Changjian; Guo, Hua

    2018-01-01

    The choice of the active degrees of freedom (DOFs) is a pivotal issue in a reduced-dimensional model of quantum dynamics when a full-dimensional one is not feasible. Here, several five-dimensional (5D) models are used to investigate the nonadiabatic photodissociation dynamics of the hydroxymethyl (CH2OH) radical, which possesses nine internal DOFs, in its lowest absorption band. A normal-mode based scheme is used to identify the active and spectator modes, and its predictions are confirmed by 5D quantum dynamical calculations. Our results underscore the important role of the CO stretching mode in the photodissociation dynamics of CH2OH, originating from the photo-induced promotion of an electron from the half-occupied π*CO antibonding orbital to a carbon Rydberg orbital.

  7. BTZ black hole from Poisson–Lie T-dualizable sigma models with spectators

    Directory of Open Access Journals (Sweden)

    A. Eghbali

    2017-09-01

    Full Text Available The non-Abelian T-dualization of the BTZ black hole is discussed in detail by using the Poisson–Lie T-duality in the presence of spectators. We explicitly construct a dual pair of sigma models related by Poisson–Lie symmetry. The original model is built on a 2+1-dimensional manifold M≈O×G, where G as a two-dimensional real non-Abelian Lie group acts freely on M, while O is the orbit of G in M. The findings of our study show that the original model indeed is canonically equivalent to the SL(2,R Wess–Zumino–Witten (WZW model for a given value of the background parameters. Moreover, by a convenient coordinate transformation we show that this model describes a string propagating in a spacetime with the BTZ black hole metric in such a way that a new family of the solutions to low energy string theory with the BTZ black hole vacuum metric, constant dilaton field and a new torsion potential is found. The dual model is built on a 2+1-dimensional target manifold M˜ with two-dimensional real Abelian Lie group G˜ acting freely on it. We further show that the dual model yields a three-dimensional charged black string for which the mass M and axion charge Q per unit length are calculated. After that, the structure and asymptotic nature of the dual space–time including the horizon and singularity are determined.

  8. Novel two-step laser ablation and ionization mass spectrometry (2S-LAIMS) of actor-spectator ice layers: Probing chemical composition of D{sub 2}O ice beneath a H{sub 2}O ice layer

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Rui, E-mail: ryang73@ustc.edu; Gudipati, Murthy S., E-mail: gudipati@jpl.nasa.gov [Science Division, Jet Propulsion Laboratory, California Institute of Technology, Mail Stop 183-301, 4800 Oak Grove Drive, Pasadena, California 91109 (United States)

    2014-03-14

    In this work, we report for the first time successful analysis of organic aromatic analytes imbedded in D{sub 2}O ices by novel infrared (IR) laser ablation of a layered non-absorbing D{sub 2}O ice (spectator) containing the analytes and an ablation-active IR-absorbing H{sub 2}O ice layer (actor) without the analyte. With these studies we have opened up a new method for the in situ analysis of solids containing analytes when covered with an IR laser-absorbing layer that can be resonantly ablated. This soft ejection method takes advantage of the tenability of two-step infrared laser ablation and ultraviolet laser ionization mass spectrometry, previously demonstrated in this lab to study chemical reactions of polycyclic aromatic hydrocarbons (PAHs) in cryogenic ices. The IR laser pulse tuned to resonantly excite only the upper H{sub 2}O ice layer (actor) generates a shockwave upon impact. This shockwave penetrates the lower analyte-containing D{sub 2}O ice layer (spectator, a non-absorbing ice that cannot be ablated directly with the wavelength of the IR laser employed) and is reflected back, ejecting the contents of the D{sub 2}O layer into the vacuum where they are intersected by a UV laser for ionization and detection by a time-of-flight mass spectrometer. Thus, energy is transmitted from the laser-absorbing actor layer into the non-absorbing spectator layer resulting its ablation. We found that isotope cross-contamination between layers was negligible. We also did not see any evidence for thermal or collisional chemistry of PAH molecules with H{sub 2}O molecules in the shockwave. We call this “shockwave mediated surface resonance enhanced subsurface ablation” technique as “two-step laser ablation and ionization mass spectrometry of actor-spectator ice layers.” This method has its roots in the well-established MALDI (matrix assisted laser desorption and ionization) method. Our method offers more flexibility to optimize both the processes—ablation and

  9. Liquid-vapor phase transition, collective flow and entropy determination from future measurements of intermediate mass fragments

    International Nuclear Information System (INIS)

    Coffin, J.P.

    1991-01-01

    Some global variables reflecting the highly collective character of nuclear matter produced in relativistic heavy-ion collisions are briefly reviewed on the basis of presently available experimental results and of Quantum Statistical Model and Quantum Molecular Dynamic Model predictions relative to intermediate mass fragments. Possible future measurements are suggested. (author) 27 refs., 8 figs

  10. String fragmentation; La fragmentation des cordes

    Energy Technology Data Exchange (ETDEWEB)

    Drescher, H.J.; Werner, K. [Laboratoire de Physique Subatomique et des Technologies Associees - SUBATECH, Centre National de la Recherche Scientifique, 44 - Nantes (France)

    1997-10-01

    The classical string model is used in VENUS as a fragmentation model. For the soft domain simple 2-parton strings were sufficient, whereas for higher energies up to LHC, the perturbative regime of the QCD gives additional soft gluons, which are mapped on the string as so called kinks, energy singularities between the leading partons. The kinky string model is chosen to handle fragmentation of these strings by application of the Lorentz invariant area law. The `kinky strings` model, corresponding to the perturbative gluons coming from pQCD, takes into consideration this effect by treating the partons and gluons on the same footing. The decay law is always the Artru-Menessier area law which is the most realistic since it is invariant to the Lorentz and gauge transformations. For low mass strings a manipulation of the rupture point is necessary if the string corresponds already to an elementary particle determined by the mass and the flavor content. By means of the fragmentation model it will be possible to simulate the data from future experiments at LHC and RHIC 3 refs.

  11. Fragmentation of jets into hadrons with strangeness in Pb-Pb collisions in ALICE at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Zimmermann, Alice [Physikalisches Institut Heidelberg (Germany); Collaboration: ALICE-Collaboration

    2014-07-01

    The research programme of the ALICE experiment at the LHC focuses on the so-called Quark-Gluon Plasma, a state of matter where quarks and gluons are deconfined. The measurement of particle jets from fragmentation of hard scatterings of partons in the colliding nuclei allows to study parton energy loss in the hot and dense medium and constrains the modelling of such a phenomenon. By measuring yields of particles like K{sup 0}{sub s}, Λ and anti Λ of low to intermediate momenta within jet cones, fragmentation into strange hadrons, as well as the baryon-meson ratio in jets can be studied. In this contribution we present first results on K{sup 0}{sub s}, Λ and anti Λ production in jets in Pb-Pb collisions at √(s{sub NN}) = 2.76 TeV. The analysis is further performed in different centrality classes, representing collisions with different impact parameters. The strangeness identified fragmentation distributions are compared to first results on inclusive fragmentation in Pb-Pb collisions.

  12. Fission fragment angular momentum

    International Nuclear Information System (INIS)

    Frenne, D. De

    1991-01-01

    Most of the energy released in fission is converted into translational kinetic energy of the fragments. The remaining excitation energy will be distributed among neutrons and gammas. An important parameter characterizing the scission configuration is the primary angular momentum of the nascent fragments. Neutron emission is not expected to decrease the spin of the fragments by more than one unit of angular momentum and is as such of less importance in the determination of the initial fragment spins. Gamma emission is a suitable tool in studying initial fragment spins because the emission time, number, energy, and multipolarity of the gammas strongly depend on the value of the primary angular momentum. The main conclusions of experiments on gamma emission were that the initial angular momentum of the fragments is large compared to the ground state spin and oriented perpendicular to the fission axis. Most of the recent information concerning initial fragment spin distributions comes from the measurement of isomeric ratios for isomeric pairs produced in fission. Although in nearly every mass chain isomers are known, only a small number are suitable for initial fission fragment spin studies. Yield and half-life considerations strongly limit the number of candidates. This has the advantage that the behavior of a specific isomeric pair can be investigated for a number of fissioning systems at different excitation energies of the fragments and fissioning nuclei. Because most of the recent information on primary angular momenta comes from measurements of isomeric ratios, the global deexcitation process of the fragments and the calculation of the initial fragment spin distribution from measured isomeric ratios are discussed here. The most important results on primary angular momentum determinations are reviewed and some theoretical approaches are given. 45 refs., 7 figs., 2 tabs

  13. What can we learn from inclusive spectra

    International Nuclear Information System (INIS)

    Nagamiya, S.

    1981-05-01

    The present experimental status on single particle inclusive measurements is described. Then, the geometrical aspect of the collision is discussed from the data of total integrated cross sections of nuclear charge or mass. The dynamical aspect of the collision, especially that for the participating region is discussed in connection with proton spectra, composite fragment spectra, pion production, ratios of π - /π + , n/p and t/ 3 He, and production of strange particles. The spectator physics is described from the data on projectile fragments

  14. Azimuthal Anisotropies in Nuclear Fragmentation

    International Nuclear Information System (INIS)

    Dabrowska, A.; Szarska, M.; Trzupek, A.; Wolter, W.; Wosiek, B.

    2002-01-01

    The directed and elliptic flow of fragments emitted from the excited projectile nuclei has been observed for 158 AGeV Pb collisions with the lead and plastic targets. For comparison the flow analysis has been performed for 10.6 AGeV Au collisions with the emulsion target. The strong directed flow of heaviest fragments is found. Light fragments exhibit directed flow opposite to that of heavy fragments. The elliptic flow for all multiply charged fragments is positive and increases with the charge of the fragment. The observed flow patterns in the fragmentation of the projectile nucleus are practically independent of the mass of the target nucleus and the collision energy. Emission of fragments in nuclear multifragmentation shows similar, although weaker, flow effects. (author)

  15. Single-Nanoflake Photo-Electrochemistry Reveals Champion and Spectator Flakes in Exfoliated MoSe2 Films

    Energy Technology Data Exchange (ETDEWEB)

    Link, Elisa M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Nanayakkara, Sanjini U [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Todt, Michael A. [Colorado State University; Isenberg, Allan E. [Colorado State University; Sambur, Justin B. [Colorado State University

    2018-03-06

    Semiconducting transition-metal dichalcogenide (TMD) nanoflake thin films are promising large-area electrodes for photo-electrochemical solar energy conversion applications. However, their energy conversion efficiencies are typically much lower than those of bulk electrodes. It is unclear to what extent this efficiency gap stems from differences among nanoflakes (e.g., area, thickness, and surface structural features). It is also unclear whether individual exfoliated nanoflakes can achieve energy conversion efficiencies similar to those of bulk crystals. Here, we use a single-nanoflake photo-electrochemical approach to show that there are both highly active and completely inactive nanoflakes within a film. For the exfoliated MoSe2 samples studied herein, 7% of nanoflakes are highly active champions, whose photocurrent efficiency exceeds that of the bulk crystal. However, 66% of nanoflakes are inactive spectators, which are mostly responsible for the overall lower photocurrent efficiency compared to the bulk crystal. The photocurrent collection efficiency increases with nanoflake area and decreases more at perimeter edges than at interior step edges. These observations, which are hidden in ensemble-level measurements, reveal the underlying performance issues of exfoliated TMD electrodes for photo-electrochemical energy conversion applications.

  16. Analysis of fission-fragment mass distribution within the quantum-mechanical fragmentation theory

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Pardeep; Kaur, Harjeet [Guru Nanak Dev University, Department of Physics, Amritsar (India)

    2016-11-15

    The fission-fragment mass distribution is analysed for the {sup 208}Pb({sup 18}O, f) reaction within the quantum-mechanical fragmentation theory (QMFT). The reaction potential has been calculated by taking the binding energies, Coulomb potential and proximity potential of all possible decay channels and a stationary Schroedinger equation has been solved numerically to calculate the fission-fragment yield. The overall results for mass distribution are compared with those obtained in experiment. Fine structure dips in yield, corresponding to fragment shell closures at Z = 50 and N=82, which are observed by Bogachev et al., are reproduced successfully in the present calculations. These calculations will help to estimate the formation probabilities of fission fragments and to understand many related phenomena occurring in the fission process. (orig.)

  17. Complement is activated in progressive multiple sclerosis cortical grey matter lesions.

    Science.gov (United States)

    Watkins, Lewis M; Neal, James W; Loveless, Sam; Michailidou, Iliana; Ramaglia, Valeria; Rees, Mark I; Reynolds, Richard; Robertson, Neil P; Morgan, B Paul; Howell, Owain W

    2016-06-22

    The symptoms of multiple sclerosis (MS) are caused by damage to myelin and nerve cells in the brain and spinal cord. Inflammation is tightly linked with neurodegeneration, and it is the accumulation of neurodegeneration that underlies increasing neurological disability in progressive MS. Determining pathological mechanisms at play in MS grey matter is therefore a key to our understanding of disease progression. We analysed complement expression and activation by immunocytochemistry and in situ hybridisation in frozen or formalin-fixed paraffin-embedded post-mortem tissue blocks from 22 progressive MS cases and made comparisons to inflammatory central nervous system disease and non-neurological disease controls. Expression of the transcript for C1qA was noted in neurons and the activation fragment and opsonin C3b-labelled neurons and glia in the MS cortical and deep grey matter. The density of immunostained cells positive for the classical complement pathway protein C1q and the alternative complement pathway activation fragment Bb was significantly increased in cortical grey matter lesions in comparison to control grey matter. The number of cells immunostained for the membrane attack complex was elevated in cortical lesions, indicating complement activation to completion. The numbers of classical (C1-inhibitor) and alternative (factor H) pathway regulator-positive cells were unchanged between MS and controls, whilst complement anaphylatoxin receptor-bearing microglia in the MS cortex were found closely apposed to cortical neurons. Complement immunopositive neurons displayed an altered nuclear morphology, indicative of cell stress/damage, supporting our finding of significant neurodegeneration in cortical grey matter lesions. Complement is activated in the MS cortical grey matter lesions in areas of elevated numbers of complement receptor-positive microglia and suggests that complement over-activation may contribute to the worsening pathology that underlies the

  18. Hypervelocity Impact Test Fragment Modeling: Modifications to the Fragment Rotation Analysis and Lightcurve Code

    Science.gov (United States)

    Gouge, Michael F.

    2011-01-01

    Hypervelocity impact tests on test satellites are performed by members of the orbital debris scientific community in order to understand and typify the on-orbit collision breakup process. By analysis of these test satellite fragments, the fragment size and mass distributions are derived and incorporated into various orbital debris models. These same fragments are currently being put to new use using emerging technologies. Digital models of these fragments are created using a laser scanner. A group of computer programs referred to as the Fragment Rotation Analysis and Lightcurve code uses these digital representations in a multitude of ways that describe, measure, and model on-orbit fragments and fragment behavior. The Dynamic Rotation subroutine generates all of the possible reflected intensities from a scanned fragment as if it were observed to rotate dynamically while in orbit about the Earth. This calls an additional subroutine that graphically displays the intensities and the resulting frequency of those intensities as a range of solar phase angles in a Probability Density Function plot. This document reports the additions and modifications to the subset of the Fragment Rotation Analysis and Lightcurve concerned with the Dynamic Rotation and Probability Density Function plotting subroutines.

  19. Fragment capture device

    Science.gov (United States)

    Payne, Lloyd R.; Cole, David L.

    2010-03-30

    A fragment capture device for use in explosive containment. The device comprises an assembly of at least two rows of bars positioned to eliminate line-of-sight trajectories between the generation point of fragments and a surrounding containment vessel or asset. The device comprises an array of at least two rows of bars, wherein each row is staggered with respect to the adjacent row, and wherein a lateral dimension of each bar and a relative position of each bar in combination provides blockage of a straight-line passage of a solid fragment through the adjacent rows of bars, wherein a generation point of the solid fragment is located within a cavity at least partially enclosed by the array of bars.

  20. Wanted! Nuclear Data for Dark Matter Astrophysics

    International Nuclear Information System (INIS)

    Gondolo, P.

    2014-01-01

    Astronomical observations from small galaxies to the largest scales in the universe can be consistently explained by the simple idea of dark matter. The nature of dark matter is however still unknown. Empirically it cannot be any of the known particles, and many theories postulate it as a new elementary particle. Searches for dark matter particles are under way: production at high-energy accelerators, direct detection through dark matter-nucleus scattering, indirect detection through cosmic rays, gamma rays, or effects on stars. Particle dark matter searches rely on observing an excess of events above background, and a lot of controversies have arisen over the origin of observed excesses. With the new high-quality cosmic ray measurements from the AMS-02 experiment, the major uncertainty in modeling cosmic ray fluxes is in the nuclear physics cross sections for spallation and fragmentation of cosmic rays off interstellar hydrogen and helium. The understanding of direct detection backgrounds is limited by poor knowledge of cosmic ray activation in detector materials, with order of magnitude differences between simulation codes. A scarcity of data on nucleon spin densities blurs the connection between dark matter theory and experiments. What is needed, ideally, are more and better measurements of spallation cross sections relevant to cosmic rays and cosmogenic activation, and data on the nucleon spin densities in nuclei

  1. Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.

    Science.gov (United States)

    Kobayashi, Masakazu; Retra, Kim; Figaroa, Francis; Hollander, Johan G; Ab, Eiso; Heetebrij, Robert J; Irth, Hubertus; Siegal, Gregg

    2010-09-01

    Fragment-based drug discovery (FBDD) has become a widely accepted tool that is complementary to high-throughput screening (HTS) in developing small-molecule inhibitors of pharmaceutical targets. Because a fragment campaign can only be as successful as the hit matter found, it is critical that the first stage of the process be optimized. Here the authors compare the 3 most commonly used methods for hit discovery in FBDD: high concentration screening (HCS), solution ligand-observed nuclear magnetic resonance (NMR), and surface plasmon resonance (SPR). They selected the commonly used saturation transfer difference (STD) NMR spectroscopy and the proprietary target immobilized NMR screening (TINS) as representative of the array of possible NMR methods. Using a target typical of FBDD campaigns, the authors find that HCS and TINS are the most sensitive to weak interactions. They also find a good correlation between TINS and STD for tighter binding ligands, but the ability of STD to detect ligands with affinity weaker than 1 mM K(D) is limited. Similarly, they find that SPR detection is most suited to ligands that bind with K(D) better than 1 mM. However, the good correlation between SPR and potency in a bioassay makes this a good method for hit validation and characterization studies.

  2. Exact Solutions of Fragmentation Equations with General Fragmentation Rates and Separable Particles Distribution Kernels

    Directory of Open Access Journals (Sweden)

    S. C. Oukouomi Noutchie

    2014-01-01

    Full Text Available We make use of Laplace transform techniques and the method of characteristics to solve fragmentation equations explicitly. Our result is a breakthrough in the analysis of pure fragmentation equations as this is the first instance where an exact solution is provided for the fragmentation evolution equation with general fragmentation rates. This paper is the key for resolving most of the open problems in fragmentation theory including “shattering” and the sudden appearance of infinitely many particles in some systems with initial finite particles number.

  3. Land fragmentation and production diversification

    NARCIS (Netherlands)

    Ciaian, Pavel; Guri, Fatmir; Rajcaniova, Miroslava; Drabik, Dusan; Paloma, Sergio Gomez Y.

    2018-01-01

    We analyze the impact of land fragmentation on production diversification in rural Albania. Albania represents a particularly interesting case for studying land fragmentation as the fragmentation is a direct outcome of land reforms. The results indicate that land fragmentation is an important driver

  4. Fragmentation processes in nuclear reactions

    International Nuclear Information System (INIS)

    Legrain, R.

    1984-08-01

    Projectile and nuclear fragmentation are defined and processes referred to are recalled. The two different aspects of fragmentation are considered but the emphasis is also put on heavy ion induced reactions. The preliminary results of an experiment performed at GANIL to study peripheral heavy ions induced reactions at intermediate energy are presented. The results of this experiment will illustrate the characteristics of projectile fragmentation and this will also give the opportunity to study projectile fragmentation in the transition region. Then nuclear fragmentation is considered which is associated with more central collisions in the case of heavy ion induced reactions. This aspect of fragmentation is also ilustrated with two heavy ion experiments in which fragments emitted at large angle have been observed

  5. Production of hypertritons in heavy ion collisions around the threshold of strangeness production

    CERN Document Server

    Hartnack, Christoph; Leifels, Yvonne; Aichelin, Jörg

    2015-01-01

    We use the Isospin Quantum Molecular Dynamics approach supplemented with a phase space coalescence to study the properties of the production of hypertritons. We see strong influences of the hyperon rescattering on the yields. The hypertritons show up to be quite aligned to the properties of nuclear matter underlining the necessity of rescattering to transport the hyperons to the spectator matter.

  6. Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies.

    Science.gov (United States)

    Kutchukian, Peter S; Wassermann, Anne Mai; Lindvall, Mika K; Wright, S Kirk; Ottl, Johannes; Jacob, Jaison; Scheufler, Clemens; Marzinzik, Andreas; Brooijmans, Natasja; Glick, Meir

    2015-06-01

    A first step in fragment-based drug discovery (FBDD) often entails a fragment-based screen (FBS) to identify fragment "hits." However, the integration of conflicting results from orthogonal screens remains a challenge. Here we present a meta-analysis of 35 fragment-based campaigns at Novartis, which employed a generic 1400-fragment library against diverse target families using various biophysical and biochemical techniques. By statistically interrogating the multidimensional FBS data, we sought to investigate three questions: (1) What makes a fragment amenable for FBS? (2) How do hits from different fragment screening technologies and target classes compare with each other? (3) What is the best way to pair FBS assay technologies? In doing so, we identified substructures that were privileged for specific target classes, as well as fragments that were privileged for authentic activity against many targets. We also revealed some of the discrepancies between technologies. Finally, we uncovered a simple rule of thumb in screening strategy: when choosing two technologies for a campaign, pairing a biochemical and biophysical screen tends to yield the greatest coverage of authentic hits. © 2014 Society for Laboratory Automation and Screening.

  7. Development of Fragmented Low-Z Ion Beams for the NA61 Experiment at the CERN SPS

    CERN Document Server

    Efthymiopoulos, I; Bohl, T; Breuker, H; Calviani, M; Manglunki, D; Mataguez, S; Maury, S; Valderanis, C; Cornelis, K; Spanggaard, J; Cettour-Cave, S; Gazdzicki, M; Seyboth, P; Guber, F; Ivashkin, A

    2011-01-01

    The NA61 experiment, aims to study the properties of the onset of deconfinement at low SPS energies and to find signatures of the critical point of strongly interacting matter. A broad range in T-μB phase diagram will be covered by performing an energy (13A-158AGeV/c) and system size (p+p, Be+Be, Ar+Ca, Xe+La) scan. In a first phase, fragmented ion beams of 7Be or 11C produced as secondaries with the same momentum per nucleon when the incident primary Pb-ion beam hits a thin Be target will be used. The H2 beam line that transports the beam to the experiment acts as a double spectrometer which combined with a new thin target (degrader) where fragments loose energy proportional to the square of their charge allows the separation of the wanted A/Z fragments. Thin scintillators and TOF measurement for the low energy points are used as particle identification devices. In this paper results from the first test of the fragmented ion beam done in 2010 will be presented showing that a pure Be beam can be obtained sa...

  8. Fragment-based drug design.

    Science.gov (United States)

    Feyfant, Eric; Cross, Jason B; Paris, Kevin; Tsao, Désirée H H

    2011-01-01

    Fragment-based drug design (FBDD), which is comprised of both fragment screening and the use of fragment hits to design leads, began more than 15 years ago and has been steadily gaining in popularity and utility. Its origin lies on the fact that the coverage of chemical space and the binding efficiency of hits are directly related to the size of the compounds screened. Nevertheless, FBDD still faces challenges, among them developing fragment screening libraries that ensure optimal coverage of chemical space, physical properties and chemical tractability. Fragment screening also requires sensitive assays, often biophysical in nature, to detect weak binders. In this chapter we will introduce the technologies used to address these challenges and outline the experimental advantages that make FBDD one of the most popular new hit-to-lead process.

  9. Fragment informatics and computational fragment-based drug design: an overview and update.

    Science.gov (United States)

    Sheng, Chunquan; Zhang, Wannian

    2013-05-01

    Fragment-based drug design (FBDD) is a promising approach for the discovery and optimization of lead compounds. Despite its successes, FBDD also faces some internal limitations and challenges. FBDD requires a high quality of target protein and good solubility of fragments. Biophysical techniques for fragment screening necessitate expensive detection equipment and the strategies for evolving fragment hits to leads remain to be improved. Regardless, FBDD is necessary for investigating larger chemical space and can be applied to challenging biological targets. In this scenario, cheminformatics and computational chemistry can be used as alternative approaches that can significantly improve the efficiency and success rate of lead discovery and optimization. Cheminformatics and computational tools assist FBDD in a very flexible manner. Computational FBDD can be used independently or in parallel with experimental FBDD for efficiently generating and optimizing leads. Computational FBDD can also be integrated into each step of experimental FBDD and help to play a synergistic role by maximizing its performance. This review will provide critical analysis of the complementarity between computational and experimental FBDD and highlight recent advances in new algorithms and successful examples of their applications. In particular, fragment-based cheminformatics tools, high-throughput fragment docking, and fragment-based de novo drug design will provide the focus of this review. We will also discuss the advantages and limitations of different methods and the trends in new developments that should inspire future research. © 2012 Wiley Periodicals, Inc.

  10. Assessment of fragment projection hazard: probability distributions for the initial direction of fragments.

    Science.gov (United States)

    Tugnoli, Alessandro; Gubinelli, Gianfilippo; Landucci, Gabriele; Cozzani, Valerio

    2014-08-30

    The evaluation of the initial direction and velocity of the fragments generated in the fragmentation of a vessel due to internal pressure is an important information in the assessment of damage caused by fragments, in particular within the quantitative risk assessment (QRA) of chemical and process plants. In the present study an approach is proposed to the identification and validation of probability density functions (pdfs) for the initial direction of the fragments. A detailed review of a large number of past accidents provided the background information for the validation procedure. A specific method was developed for the validation of the proposed pdfs. Validated pdfs were obtained for both the vertical and horizontal angles of projection and for the initial velocity of the fragments. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Knowledge-based Fragment Binding Prediction

    Science.gov (United States)

    Tang, Grace W.; Altman, Russ B.

    2014-01-01

    Target-based drug discovery must assess many drug-like compounds for potential activity. Focusing on low-molecular-weight compounds (fragments) can dramatically reduce the chemical search space. However, approaches for determining protein-fragment interactions have limitations. Experimental assays are time-consuming, expensive, and not always applicable. At the same time, computational approaches using physics-based methods have limited accuracy. With increasing high-resolution structural data for protein-ligand complexes, there is now an opportunity for data-driven approaches to fragment binding prediction. We present FragFEATURE, a machine learning approach to predict small molecule fragments preferred by a target protein structure. We first create a knowledge base of protein structural environments annotated with the small molecule substructures they bind. These substructures have low-molecular weight and serve as a proxy for fragments. FragFEATURE then compares the structural environments within a target protein to those in the knowledge base to retrieve statistically preferred fragments. It merges information across diverse ligands with shared substructures to generate predictions. Our results demonstrate FragFEATURE's ability to rediscover fragments corresponding to the ligand bound with 74% precision and 82% recall on average. For many protein targets, it identifies high scoring fragments that are substructures of known inhibitors. FragFEATURE thus predicts fragments that can serve as inputs to fragment-based drug design or serve as refinement criteria for creating target-specific compound libraries for experimental or computational screening. PMID:24762971

  12. Jet reconstruction and measurement of identified fragmentation functions in Pb-Pb and pp collisions with the ALICE experiment

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Xianguo; Busch, Oliver [Physikalisches Institut, Heidelberg (Germany); Collaboration: ALICE-Collaboration

    2014-07-01

    Jets are defined in QCD as cascades of consecutive emission of partons from an initial hard scattering. The process of parton showering and subsequent hadronisation is broadly known as fragmentation. High energy nucleus-nucleus collisions allow us to probe parton fragmentation within a QCD medium and the properties of this medium via the modification of the jet spectrum and jet structure. Jet reconstruction in pp collisions provides an elementary baseline and allows to investigate perturbative and non-perturbative aspects of particle production. In addition to inclusive probes, identified particles in the final states provide an enhanced sensitivity to the flavor dependence of fragmentation and nuclear modifications. ALICE at the CERN LHC is a general-purpose heavy ion experiment designed to study the physics of strongly interacting matter and the Quark-Gluon-Plasma. It has an excellent tracking and particle identification performance over a wide momentum range. In this talk we present results on inclusive jet observable as well as the novel measurements of identified fragmentation functions in pp and Pb-Pb collisions. The results are confronted with theory predictions.

  13. Brainwashing the cybernetic spectator: The Ipcress File, 1960s cinematic spectacle and the sciences of mind.

    Science.gov (United States)

    Holmes, Marcia

    2017-07-01

    This article argues that the mid-1960s saw a dramatic shift in how 'brainwashing' was popularly imagined, reflecting Anglo-American developments in the sciences of mind as well as shifts in mass media culture. The 1965 British film The Ipcress File (dir. Sidney J. Furie, starr. Michael Caine) provides a rich case for exploring these interconnections between mind control, mind science and media, as it exemplifies the era's innovations for depicting 'brainwashing' on screen: the film's protagonist is subjected to flashing lights and electronic music, pulsating to the 'rhythm of brainwaves'. This article describes the making of The Ipcress File 's brainwashing sequence and shows how its quest for cinematic spectacle drew on developments in cybernetic science, multimedia design and modernist architecture (developments that were also influencing the 1960s psychedelic counter-culture). I argue that often interposed between the disparate endeavours of 1960s mind control, psychological science and media was a vision of the human mind as a 'cybernetic spectator': a subject who scrutinizes how media and other demands on her sensory perception can affect consciousness, and seeks to consciously participate in this mental conditioning and guide its effects.

  14. Fragmentation in the branching coral Acropora palmata (Lamarck): growth, survivorship, and reproduction of colonies and fragments.

    Science.gov (United States)

    Lirman

    2000-08-23

    Acropora palmata, a branching coral abundant on shallow reef environments throughout the Caribbean, is susceptible to physical disturbance caused by storms. Accordingly, the survivorship and propagation of this species are tied to its capability to recover after fragmentation. Fragments of A. palmata comprised 40% of ramets within populations that had experienced recent storms. While the survivorship of A. palmata fragments was not directly related to the size of fragments, removal of fragments from areas where they settled was influenced by size. Survivorship of fragments was also affected by type of substratum; the greatest mortality (58% loss within the first month) was observed on sand, whereas fragments placed on top of live colonies of A. palmata fused to the underlying tissue and did not experience any losses. Fragments created by Hurricane Andrew on a Florida reef in August 1992 began developing new growth (proto-branches) 7 months after the storm. The number of proto-branches on fragments was dependent on size, but growth was not affected by the size of fragments. Growth-rates of proto-branches increased exponentially with time (1.7 cm year(-1) for 1993-1994, 2.7 cm year(-1) for 1994-1995, 4.2 cm year(-1) for 1995-1996, and 6.5 cm year(-1) for 1996-1997), taking over 4 years for proto-branches to achieve rates comparable to those of adult colonies on the same reef (6.9 cm year(-1)). In addition to the initial mortality and reduced growth-rates, fragmentation resulted in a loss of reproductive potential. Neither colonies that experienced severe fragmentation nor fragments contained gametes until 4 years after the initial damage. Although A. palmata may survive periodic fragmentation, the long-term effects of this process will depend ultimately on the balance between the benefits and costs of this process.

  15. Plasminogen fragments K 1-3 and K 5 bind to different sites in fibrin fragment DD.

    Science.gov (United States)

    Grinenko, T V; Kapustianenko, L G; Yatsenko, T A; Yusova, O I; Rybachuk, V N

    2016-01-01

    Specific plasminogen-binding sites of fibrin molecule are located in Аα148-160 regions of C-terminal domains. Plasminogen interaction with these sites initiates the activation process of proenzyme and subsequent fibrin lysis. In this study we investigated the binding of plasminogen fragments K 1-3 and K 5 with fibrin fragment DD and their effect on Glu-plasminogen interaction with DD. It was shown that the level of Glu-plasminogen binding to fibrin fragment DD is decreased by 50-60% in the presence of K 1-3 and K 5. Fragments K 1-3 and K 5 have high affinity to fibrin fragment DD (Kd is 0.02 for K 1-3 and 0.054 μМ for K 5). K 5 interaction is independent and K 1-3 is partly dependent on C-terminal lysine residues. K 1-3 interacts with complex of fragment DD-immobilized K 5 as well as K 5 with complex of fragment DD-immobilized K 1-3. The plasminogen fragments do not displace each other from binding sites located in fibrin fragment DD, but can compete for the interaction. The results indicate that fibrin fragment DD contains different binding sites for plasminogen kringle fragments K 1-3 and K 5, which can be located close to each other. The role of amino acid residues of fibrin molecule Аα148-160 region in interaction with fragments K 1-3 and K 5 is discussed.

  16. Fractal statistics of brittle fragmentation

    Directory of Open Access Journals (Sweden)

    M. Davydova

    2013-04-01

    Full Text Available The study of fragmentation statistics of brittle materials that includes four types of experiments is presented. Data processing of the fragmentation of glass plates under quasi-static loading and the fragmentation of quartz cylindrical rods under dynamic loading shows that the size distribution of fragments (spatial quantity is fractal and can be described by a power law. The original experimental technique allows us to measure, apart from the spatial quantity, the temporal quantity - the size of time interval between the impulses of the light reflected from the newly created surfaces. The analysis of distributions of spatial (fragment size and temporal (time interval quantities provides evidence of obeying scaling laws, which suggests the possibility of self-organized criticality in fragmentation.

  17. Dark matter gravitinos and baryons via Q-ball decay in the gauge-mediated MSSM

    International Nuclear Information System (INIS)

    Doddato, Francesca; McDonald, John

    2013-01-01

    We show that late Q-ball decay in the MSSM with gauge-mediated SUSY breaking can provide a natural source of non-thermal NLSPs which subsequently decay to gravitino dark matter without violating nucleosynthesis constraints. To show this, we perform a global analysis of Q-ball formation and decay in Affleck-Dine baryogenesis for a d = 6 (u c d c d c ) 2 flat direction of the gauge-mediated MSSM. A general phenomenological potential for the flat-direction is studied and the Q-ball decay properties are obtained as a function of its parameters. The corresponding gravitino mass necessary to account for dark matter is then determined for the case of stau NLSPs. The decay temperature depends on the charge of the Q-balls, which is determined by the fragmentation of the AD condensate. Different fragmentation scenarios are considered, and the final non-thermal NLSP density from Q-ball decay and NLSP annihilation is determined. Particular care is taken to establish that NLSPs from Q-ball decay become homogeneous and non-relativistic prior to annihilation. The gravitino mass necessary for dark matter is naturally consistent with the theoretical gravitino mass in the gauge-mediation model

  18. Quark mobility in extended nuclear matter

    International Nuclear Information System (INIS)

    Sivers, D.

    1988-01-01

    The propagation of an energetic quark through extended nuclear matter is analyzed in terms of a simple model in which localization of color is imposed through chromoelectric flux tubes. A mobile quark in the nuclear medium creates a disturbance which affects neighboring nucleons. The model suggests that the spatial properties of the disturbance involve a competition among different dynamical mechanisms. Experimental measurements involving the target fragmentation region in deep-inelastic leptoproduction on large nuclei may help specify some of the important features of nuclear dynamics. copyright 1988 Academic Press, Inc

  19. Correlations between isospin dynamics and Intermediate Mass Fragments emission time scales: a probe for the symmetry energy in asymmetric nuclear matter

    International Nuclear Information System (INIS)

    De Filippo, E; Cardella, G; Guidara, E La; Pagano, A; Papa, M; Amorini, F; Colonna, M; Gianì, S; Grassi, L; Han, J; Maiolino, C; Auditore, L; Minniti, T; Baran, V; Berceanu, I; Geraci, E; Grzeszczuk, A; Guazzoni, P; Lanzalone, G; Lombardo, I

    2013-01-01

    We show new data from the 64 Ni+ 124 Sn and 58 Ni+ 112 Sn reactions studied in direct kinematics with the CHIMERA detector at INFN-LNS and compared with the reverse kinematics reactions at the same incident beam energy (35 A MeV). Analyzing the data with the method of relative velocity correlations, fragments coming from statistical decay of an excited projectile-like (PLF) or target-like (TLF) fragments are discriminated from the ones coming from dynamical emission in the early stages of the reaction. By comparing data of the reverse kinematics experiment with a stochastic mean field (SMF) + GEMINI calculations our results show that observables from neck fragmentation mechanism add valuable constraints on the density dependence of symmetry energy. An indication is found for a moderately stiff symmetry energy potential term of EOS.

  20. Studies of complex fragment emission in heavy ion reactions

    International Nuclear Information System (INIS)

    Charity, R.J.; Sobotka, L.G.

    1992-01-01

    Our work involves the study of intermediate energy heavy-ion nuclear reactions. This work has two foci. On the one hand, we desire to learn about the properties of nuclear matter under abnormal conditions, in this energy domain, predominately low densities. This purpose runs abreast of the second, which is the study of the relevant reaction mechanisms. The two objectives are inexorably linked because our experimental laboratory for studying nuclear matter properties is a dynamic one. We are forced to ask how nuclear matter properties, such as phase transitions, are reflected in the dynamics of the reactions. It may be that irrefutable information about nuclear matter will not be extracted from the reaction work. Nevertheless, we are compelled to undertake this effort not only because it is the only game in town and as yet we do not know that information cannot be extracted, but also because of our second objective. The process leads to an understanding of the reaction mechanism themselves and therefore to the response characteristics of finite, perhaps non-equilibrium, strongly interacting systems. Our program has been: To study energy, mass, and angular momentum deposition by studying incomplete fusion reactions. To gain confidence that we understand how highly excited systems decompose by studying all emissions from the highly excited systems. To push these kinds of studies into the intermediate energy domain, with excitation function studies. And attempt to learn about the dynamics of the decays using particle-particle correlations. In the last effort, we have decided to focus on simple systems, where we believe, definitive statements are possible. These avenues of research share a common theme, large complex fragment production

  1. Study of stochastic approaches of the n-bodies problem: application to the nuclear fragmentation

    International Nuclear Information System (INIS)

    Guarnera, A.

    1996-01-01

    In the last decade nuclear physics research has found, with the observation of phenomena such as multifragmentation or vaporization, the possibility to get a deeper insight into the nuclear matter phase diagram. For example, a spinodal decomposition scenario has been proposed to explain the multifragmentation: because of the initial compression, the system may enter a region, the spinodal zone, in which the nuclear matter is no longer stable, and so any fluctuation leads to the formation of fragments. This thesis deals with spinodal decomposition within the theoretical framework of stochastic mean filed approaches, in which the one-body density function may experience a stochastic evolution. We have shown that these approaches are able to describe phenomena, such as first order phase transitions, in which fluctuations and many-body correlations plan an important role. In the framework of stochastic mean-filed approaches we have shown that the fragment production by spinodal decomposition is characterized by typical time scales of the order of 100 fm/c and by typical size scales around the Neon mass. We have also shown that these features are robust and that they are not affected significantly by a possible expansion of the system or by the finite size of nuclei. We have proposed as a signature of the spinodal decomposition some typical partition of the largest fragments. The study and the comparison with experimental data, performed for the reactions Xe + Cu at 45 MeV/A and Xe + Sn at 50 MeV/A, have shown a remarkable agreement. Moreover we would like to stress that the theory does not contain any adjustable parameter. These results seem to give a strong indication of the possibility to observe a spinodal decomposition of nuclei. (author)

  2. ANGULAR MOMENTUM TRANSFER AND LACK OF FRAGMENTATION IN SELF-GRAVITATING ACCRETION FLOWS

    International Nuclear Information System (INIS)

    Begelman, Mitchell C.; Shlosman, Isaac

    2009-01-01

    Rapid inflows associated with early galaxy formation lead to the accumulation of self-gravitating gas in the centers of proto-galaxies. Such gas accumulations are prone to nonaxisymmetric instabilities, as in the well known Maclaurin sequence of rotating ellipsoids, which are accompanied by a catastrophic loss of angular momentum (J). Self-gravitating gas is also intuitively associated with star formation. However, recent simulations of the infall process display highly turbulent continuous flows. We propose that J-transfer, which enables the inflow, also suppresses fragmentation. Inefficient J loss by the gas leads to decay of turbulence, triggering global instabilities and renewed turbulence driving. Flow regulated in this way is stable against fragmentation, while staying close to the instability threshold for bar formation-thick self-gravitating disks are prone to global instabilities before they become unstable locally. On smaller scales, the fraction of gravitationally unstable matter swept up by shocks in such a flow is a small and decreasing function of the Mach number. We conclude counterintuitively that gas able to cool down to a small fraction of its virial temperature will not fragment as it collapses. This provides a venue for supermassive black holes to form via direct infall, without the intermediary stage of forming a star cluster. Some black holes could have formed or grown in massive halos at low redshifts. Thus the fragmentation is intimately related to J redistribution within the system: it is less dependent on the molecular/metal cooling but is conditioned by the ability of the flow to develop virial, supersonic turbulence.

  3. Role of electroweak radiation in predictions for dark matter indirect detection

    Energy Technology Data Exchange (ETDEWEB)

    Ali Cavasonza, Leila; Pellen, Mathieu; Kraemer, Michael [RWTH Aachen, Aachen (Germany)

    2015-07-01

    A very exciting challenge in particle and astroparticle physics is the exploration of the nature of dark matter. The evidences of the existence of dark matter are also the strongest phenomenological indications for physics beyond the Standard Model. A huge experimental effort is currently made at colliders and via astrophysical experiments to shed light on the nature of dark matter: dark matter may be produced at colliders or detected through direct and indirect detection experiments. The interplay and complementarity between these different approaches offers extraordinary opportunities to improve our understanding of the nature of dark matter or to set constraints on dark matter models. In indirect detection one searches for dark matter annihilation products, that produce secondary antimatter particles like positrons and antiprotons. Such antimatter particles propagate through the Galaxy and can be detected at Earth by astrophysical experiments. Particularly interesting is the importance of electroweak corrections to the predictions for the expected fluxes at Earth. The inclusion of EW radiation from the primary dark matter annihilation products can significantly affect the spectra of the secondary SM particles. The EW radiation can be described using fragmentation functions, as done for instance in QCD. We study the quality of this approximation in a simplified SUSY model and in a UED model.

  4. Universality of projectile fragmentation model

    International Nuclear Information System (INIS)

    Chaudhuri, G.; Mallik, S.; Das Gupta, S.

    2012-01-01

    Presently projectile fragmentation reaction is an important area of research as it is used for the production of radioactive ion beams. In this work, the recently developed projectile fragmentation model with an universal temperature profile is used for studying the charge distributions of different projectile fragmentation reactions with different projectile target combinations at different incident energies. The model for projectile fragmentation consists of three stages: (i) abrasion, (ii) multifragmentation and (iii) evaporation

  5. Semi-exclusive study of the reaction Ar + Ag at 35 A MeV

    International Nuclear Information System (INIS)

    Ployart, G.

    1985-07-01

    The experiment was carried out at the GANIL and was the object of the first starting up of the hodoscope bound up with the lid of the reaction chamber NAUTILUS. Although the detection equipment was not planned for a detailed analysis of light (O-Ar) and fast nuclei (beam velocity), many indications converge to attribute their origin to a mechanism alike projectile fragmentation when it is not a matter of transfer. Furthermore, the lack at 35 A.MeV of evaporation residues from the quasi-complete fusion nucleus, still present at 27 A.MeV, shows that one has exceeded the maximum excitation energy bearable by the system. Most light particles spectra can be understood in term of evaporation from a nucleus more or less thermalised; for the others (fast alphas and lithiums detected in frontal collisions), one has to suppose a target transparency for some nucleons of the projectile. The main evaporation sources have considered are, for central collisions, the quasi complete fusion nuclei (before their dislocation into light fragments) and, for peripheral collisions, the quasi targets and quasi projectiles associated with spectator nuclei of the ablation model. In this last case, the consideration of the participant zone as an evaporating source of middle speed raises some difficulties [fr

  6. Effective Fragment Potential Method for H-Bonding: How To Obtain Parameters for Nonrigid Fragments.

    Science.gov (United States)

    Dubinets, Nikita; Slipchenko, Lyudmila V

    2017-07-20

    Accuracy of the effective fragment potential (EFP) method was explored for describing intermolecular interaction energies in three dimers with strong H-bonded interactions, formic acid, formamide, and formamidine dimers, which are a part of HBC6 database of noncovalent interactions. Monomer geometries in these dimers change significantly as a function of intermonomer separation. Several EFP schemes were considered, in which fragment parameters were prepared for a fragment in its gas-phase geometry or recomputed for each unique fragment geometry. Additionally, a scheme in which gas-phase fragment parameters are shifted according to relaxed fragment geometries is introduced and tested. EFP data are compared against the coupled cluster with single, double, and perturbative triple excitations (CCSD(T)) method in a complete basis set (CBS) and the symmetry adapted perturbation theory (SAPT). All considered EFP schemes provide a good agreement with CCSD(T)/CBS for binding energies at equilibrium separations, with discrepancies not exceeding 2 kcal/mol. However, only the schemes that utilize relaxed fragment geometries remain qualitatively correct at shorter than equilibrium intermolecular distances. The EFP scheme with shifted parameters behaves quantitatively similar to the scheme in which parameters are recomputed for each monomer geometry and thus is recommended as a computationally efficient approach for large-scale EFP simulations of flexible systems.

  7. Casual spectators and die-hard fans’ reactions to their team defeat: A look at the role of territorial identification in elite French rugby

    Directory of Open Access Journals (Sweden)

    Iouri Bernache-Assollant

    2012-01-01

    Full Text Available This research investigated the role of two foci of identification (team and territory on identity management strategies used by sport followers in the particular context of elite French rugby union. In study 1 which dealt with casual spectators (N = 153, the results corroborated numerous studies conducted in the North-American context and showed that team identification constitutes a strong driver for offensive and loyalty reactions. In study 2 which dealt with die-hard fans (N = 64, it appeared that team identification seems to be the best predictor of team loyalty strategy whereas territorial identification seems to be the first predictor of offensive strategies. Taken together, the studies showed the importance of considering the specific context in which sport fanship takes place.

  8. Robust Object Tracking Using Valid Fragments Selection.

    Science.gov (United States)

    Zheng, Jin; Li, Bo; Tian, Peng; Luo, Gang

    Local features are widely used in visual tracking to improve robustness in cases of partial occlusion, deformation and rotation. This paper proposes a local fragment-based object tracking algorithm. Unlike many existing fragment-based algorithms that allocate the weights to each fragment, this method firstly defines discrimination and uniqueness for local fragment, and builds an automatic pre-selection of useful fragments for tracking. Then, a Harris-SIFT filter is used to choose the current valid fragments, excluding occluded or highly deformed fragments. Based on those valid fragments, fragment-based color histogram provides a structured and effective description for the object. Finally, the object is tracked using a valid fragment template combining the displacement constraint and similarity of each valid fragment. The object template is updated by fusing feature similarity and valid fragments, which is scale-adaptive and robust to partial occlusion. The experimental results show that the proposed algorithm is accurate and robust in challenging scenarios.

  9. Self-organized criticality in fragmenting

    DEFF Research Database (Denmark)

    Oddershede, L.; Dimon, P.; Bohr, J.

    1993-01-01

    The measured mass distributions of fragments from 26 fractured objects of gypsum, soap, stearic paraffin, and potato show evidence of obeying scaling laws; this suggests the possibility of self-organized criticality in fragmenting. The probability of finding a fragment scales inversely to a power...

  10. Energy production using fission fragment rockets

    International Nuclear Information System (INIS)

    Chapline, G.; Matsuda, Y.

    1991-08-01

    Fission fragment rockets are nuclear reactors with a core consisting of thin fibers in a vacuum, and which use magnetic fields to extract the fission fragments from the reactor core. As an alternative to ordinary nuclear reactors, fission fragment rockets would have the following advantages: Approximately twice as efficient if one can directly convert the fission fragment energy into electricity; by reducing the buildup of a fission fragment inventory in the reactor one could avoid a Chernobyl type disaster; and collecting the fission fragments outside the reactor could simplify the waste disposal problem. 6 refs., 4 figs., 2 tabs

  11. Does the Chemothermal Instability Have Any Role in the Fragmentation of Primordial Gas

    Science.gov (United States)

    Dutta, Jayanta

    2015-10-01

    The collapse of the primordial gas in the density regime ˜108-1010 cm-3 is controlled by the three-body H2 formation process, in which the gas can cool faster than free-fall time—a condition proposed as the chemothermal instability. We investigate how the heating and cooling rates are affected during the rapid transformation of atomic to molecular hydrogen. With a detailed study of the heating and cooling balance in a 3D simulation of Pop III collapse, we follow the chemical and thermal evolution of the primordial gas in two dark matter minihalos. The inclusion of sink particles in modified Gadget-2 smoothed particle hydrodynamics code allows us to investigate the long-term evolution of the disk that fragments into several clumps. We find that the sum of all the cooling rates is less than the total heating rate after including the contribution from the compressional heating (pdV). The increasing cooling rate during the rapid increase of the molecular fraction is offset by the unavoidable heating due to gas contraction. We conclude that fragmentation occurs because H2 cooling, the heating due to H2 formation and compressional heating together set a density and temperature structure in the disk that favors fragmentation, not the chemothermal instability.

  12. DOES THE CHEMOTHERMAL INSTABILITY HAVE ANY ROLE IN THE FRAGMENTATION OF PRIMORDIAL GAS

    International Nuclear Information System (INIS)

    Dutta, Jayanta

    2015-01-01

    The collapse of the primordial gas in the density regime ∼10 8 −10 10 cm −3 is controlled by the three-body H 2 formation process, in which the gas can cool faster than free-fall time—a condition proposed as the chemothermal instability. We investigate how the heating and cooling rates are affected during the rapid transformation of atomic to molecular hydrogen. With a detailed study of the heating and cooling balance in a 3D simulation of Pop III collapse, we follow the chemical and thermal evolution of the primordial gas in two dark matter minihalos. The inclusion of sink particles in modified Gadget-2 smoothed particle hydrodynamics code allows us to investigate the long-term evolution of the disk that fragments into several clumps. We find that the sum of all the cooling rates is less than the total heating rate after including the contribution from the compressional heating (pdV). The increasing cooling rate during the rapid increase of the molecular fraction is offset by the unavoidable heating due to gas contraction. We conclude that fragmentation occurs because H 2 cooling, the heating due to H 2 formation and compressional heating together set a density and temperature structure in the disk that favors fragmentation, not the chemothermal instability

  13. Plasma wake and nuclear forces on fragmented H+ transport

    International Nuclear Information System (INIS)

    Barriga-Carrasco, Manuel D; Deutsch, Claude

    2006-01-01

    The objective of the present work is to study the target electronic and nuclear interactions produced when a H + ion traverses classical plasma matter. Electronic interactions are treated by means of the dielectric formalism while nuclear interactions are dealt within the classical dispersion theory through a Monte Carlo computer code. The interactions through plasma electronic medium among close ions are called wake forces. We checked that these forces screen the Coulomb explosions of the two fragmented protons from the same H + ion decreasing their relative distance in the analysed cases. These forces align the interproton vector along the motion direction. They also tend the two-proton energy loss to the value of two isolated protons when at early times it is rather larger. Nevertheless most parts of these wake effects cannot be corroborated experimentally as they are masked by the projectile collisions with target nuclei in our numerical experiment. These collisions cancel the screening produced by the wake forces, increasing the interproton distance even faster than for bare Coulomb explosion. Also they misalign the interproton vector along the motion direction and contribute moderately to increase the energy loss of the fragmented H + ion. These nuclear collisions effects are more significant in reducing projectile velocity

  14. Heavy flavor puzzle at LHC: a serendipitous interplay of jet suppression and fragmentation.

    Science.gov (United States)

    Djordjevic, Magdalena

    2014-01-31

    Both charged hadrons and D mesons are considered to be excellent probes of QCD matter created in ultrarelativistic heavy ion collisions. Surprisingly, recent experimental observations at LHC show the same jet suppression for these two probes, which--contrary to pQCD expectations--may suggest similar energy losses for light quarks and gluons in the QCD medium. We here use our recently developed energy loss formalism in a finite-size dynamical QCD medium to analyze this phenomenon that we denote as the "heavy flavor puzzle at LHC." We show that this puzzle is a consequence of an unusual combination of the suppression and fragmentation patterns and, in fact, does not require invoking the same energy loss for light partons. Furthermore, we show that this combination leads to a simple relationship between the suppressions of charged hadrons and D mesons and the corresponding bare quark suppressions. Consequently, a coincidental matching of jet suppression and fragmentation allows considerably simplifying the interpretation of the corresponding experimental data.

  15. A database of fragmentation cross section measurements applicable to cosmic ray propagation calculations

    International Nuclear Information System (INIS)

    Crawford, H.J.; Engelage, J.; Jones, F.C.

    1989-08-01

    A database of single particle inclusive fragment production cross section measurements has been established and is accessible over common computer networks. These measurements have been obtained from both published literature and direct communication with experimenters and include cross sections for nuclear beams on H, He, and heavier targets, and for H and He beams on nuclear targets, for energies >30 MeV/nucleon. These cross sections are directly applicable to calculations involving cosmic ray nuclear interactions with matter. The data base includes projectile, target, and fragment specifications, beam energy, cross section with uncertainty, literature reference, and comment code. It is continuously updated to assure accuracy and completeness. Also available are widely used semi-empirical formulations for calculating production cross sections and excitation functions. In this paper we discuss the database in detail and describe how it can be accessed. We compare the measurements with semi-empirical calculations and point out areas where improved calculations and further cross section measurements are required. 5 refs., 2 figs

  16. Detection of fission fragments by secondary emission; Detection des fragments de fission par emission secondaire

    Energy Technology Data Exchange (ETDEWEB)

    Audias, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    This fission fragment detecting apparatus is based on the principle that fragments traversing a thin foil will cause emission of secondary electrons. These electrons are then accelerated (10 kV) and directly detected by means of a plastic scintillator and associated photomultiplier. Some of the advantages of such a detector are, its rapidity, its discriminating power between alpha particles and fission fragments, its small energy loss in detecting the fragments and the relatively great amount of fissionable material which it can contain. This paper is subdivided as follows: a) theoretical considerations b) constructional details of apparatus and some experimental details and c) a study of the secondary emission effect itself. (author) [French] Le detecteur de fragments de fission que nous avons realise est base sur le principe de l'emission secondaire produite par les fragments de fission traversant une feuille mince: les electrons secondaires emis sont acceleres a des tensions telles (de l'ordre de 10 kV), qu'ils soient directement detectables par un scintillateur plastique associe a un photomultiplicateur. L'interet d'un tel detecteur reside: dans sa rapidite, sa tres bonne discrimination alpha, fission, la possibilite de detecter les fragments de fission avec une perte d'energie pouvant rester relativement faible, et la possibilite d'introduire des quantites de matiere fissile plus importantes que dans les autres types de detecteurs. Ce travail comporte: -) un apercu bibliographique de la theorie du phenomene, -) realisation et mise au point du detecteur avec etude experimentale de quelques parametres intervenant dans l'emission secondaire, -) etude de l'emission secondaire (sur la face d'emergence des fragments de fission) en fonction de l'energie du fragment et en fonction de l'epaisseur de matiere traversee avant emission secondaire, et -) une etude comparative de l'emission secondaire sur la face d'incidence et sur la face d'emergence des fragments de

  17. Thermodynamics of the fuel fragmentation gas

    International Nuclear Information System (INIS)

    Perez, R.B.; Alsmiller, R.G. Jr.

    1977-01-01

    In the context of nuclear reactor safety studies, a program is in progress at ORNL whereby fuel-fragmentation situations are mocked up by the application of high-current capacitor discharges through solid UO 2 samples. The goal of the present work is to predict such quantities as the number of gas and liquid fragments and their energy distributions. The point of view adopted is that upon fragmentation, a cloud of UO 2 vapor is formed containing ''primeval'' liquid fragments which act as condensation centers. In the evolution of time, fragment growth is controlled by nucleation, coagulation and evaporation processes. Eventually, the vapor-droplet system will reach a situation in which clusters (fragments) of various sizes and UO 2 vapor will coexist in an ''association-disassociation'' equilibrium. Thus, the physical model considered here consists of the identification of the fragmentation gas with an ''imperfect'' vapor, made up of interacting UO 2 vapor and liquid fragments. The results of the study are presented

  18. Feasibility Study for the Measurement of Nuclear Fragmentation Cross Sections with NA61/SHINE at the CERN SPS

    CERN Document Server

    Aduszkiewicz, A

    2017-01-01

    A detailed knowledge of the fragmentation cross sections of intermediate mass nuclei is of paramount importance to understand the propagation of cosmic rays in our Galaxy and to evaluate the background for dark matter searches with space-based cosmic-ray experiments such as AMS. Therefore, we suggest a one-week test run in 2018 with secondary ions to establish the capabilities of NA61/SHINE to measure fragmentation cross sections at isotope level. No major modifications to the experimental setup of NA61/SHINE are needed to perform this feasibility study. The experience gained during the test run will be used to formulate a comprehensive measurement campaign for cosmic-ray related fragmentation cross sections for the possible extension of the NA61/SHINE physics program beyond 2020. The test data on carbon-proton and oxygen-proton interactions at 13A GeV/c that we intend to collect during the proposed test run have already the potential to reduce the current cross section uncertainties.

  19. The dual role of fragments in fragment-assembly methods for de novo protein structure prediction

    Science.gov (United States)

    Handl, Julia; Knowles, Joshua; Vernon, Robert; Baker, David; Lovell, Simon C.

    2013-01-01

    In fragment-assembly techniques for protein structure prediction, models of protein structure are assembled from fragments of known protein structures. This process is typically guided by a knowledge-based energy function and uses a heuristic optimization method. The fragments play two important roles in this process: they define the set of structural parameters available, and they also assume the role of the main variation operators that are used by the optimiser. Previous analysis has typically focused on the first of these roles. In particular, the relationship between local amino acid sequence and local protein structure has been studied by a range of authors. The correlation between the two has been shown to vary with the window length considered, and the results of these analyses have informed directly the choice of fragment length in state-of-the-art prediction techniques. Here, we focus on the second role of fragments and aim to determine the effect of fragment length from an optimization perspective. We use theoretical analyses to reveal how the size and structure of the search space changes as a function of insertion length. Furthermore, empirical analyses are used to explore additional ways in which the size of the fragment insertion influences the search both in a simulation model and for the fragment-assembly technique, Rosetta. PMID:22095594

  20. Models of fragmentation with composite power laws

    Science.gov (United States)

    Tavassoli, Z.; Rodgers, G. J.

    1999-06-01

    Some models for binary fragmentation are introduced in which a time dependent transition size produces two regions of fragment sizes above and below the transition size. In the first model we assume a fixed rate of fragmentation for the largest fragment and two different rates of fragmentation in the two regions of sizes above and below the transition size. The model is solved exactly in the long time limit to reveal stable time-invariant solutions for the fragment size and mass distributions. These solutions exhibit composite power law behaviours; power laws with two different exponents for fragments in smaller and larger regions. A special case of the model with no fragmentation in the smaller size region is also examined. Another model is also introduced which have three regions of fragment sizes with different rates of fragmentation. The similarities between the stable distributions in our models and composite power law distributions from experimental work on shock fragmentation of long thin glass rods and thick clay plates are discussed.

  1. Kinetics of fragmentation-annihilation processes

    OpenAIRE

    Filipe, JAN; Rodgers, GJ

    1996-01-01

    We investigate the kinetics of systems in which particles of one species undergo binary fragmentation and pair annihilation. In the latter, nonlinear process, fragments react at collision to produce an inert species, causing loss of mass. We analyze these systems in the reaction-limited regime by solving a continuous model within the mean-field approximation. The rate of fragmentation for a particle of mass x to break into fragments of masses y and x-y has the form x(lambda-1) (lambda > 0), a...

  2. Fission fragment spins and spectroscopy

    International Nuclear Information System (INIS)

    Durell, J.L.

    1988-01-01

    Prompt γ-ray coincidence experiments have been carried out on γ-rays emitted from post-neutron emission fission fragments produced by the aup 19F + 197 Au and 18 O + 232 Th reactions. Decay schemes have been established for even-even nuclei ranging from 78 Se to 148 Nd. Many new states with spin up to ∼ 12h have been observed. Apart from providing a wealth of new information on the spectroscopy of neutron-rich nuclei, the data have been analyzed to determine the average spin of primary fission fragments as a function of fragment mass. The results suggest that the fragment spins are determined by the temperature and shape of the primary fragments at or near to scission

  3. Quantum mechanical fragment methods based on partitioning atoms or partitioning coordinates.

    Science.gov (United States)

    Wang, Bo; Yang, Ke R; Xu, Xuefei; Isegawa, Miho; Leverentz, Hannah R; Truhlar, Donald G

    2014-09-16

    Conspectus The development of more efficient and more accurate ways to represent reactive potential energy surfaces is a requirement for extending the simulation of large systems to more complex systems, longer-time dynamical processes, and more complete statistical mechanical sampling. One way to treat large systems is by direct dynamics fragment methods. Another way is by fitting system-specific analytic potential energy functions with methods adapted to large systems. Here we consider both approaches. First we consider three fragment methods that allow a given monomer to appear in more than one fragment. The first two approaches are the electrostatically embedded many-body (EE-MB) expansion and the electrostatically embedded many-body expansion of the correlation energy (EE-MB-CE), which we have shown to yield quite accurate results even when one restricts the calculations to include only electrostatically embedded dimers. The third fragment method is the electrostatically embedded molecular tailoring approach (EE-MTA), which is more flexible than EE-MB and EE-MB-CE. We show that electrostatic embedding greatly improves the accuracy of these approaches compared with the original unembedded approaches. Quantum mechanical fragment methods share with combined quantum mechanical/molecular mechanical (QM/MM) methods the need to treat a quantum mechanical fragment in the presence of the rest of the system, which is especially challenging for those parts of the rest of the system that are close to the boundary of the quantum mechanical fragment. This is a delicate matter even for fragments that are not covalently bonded to the rest of the system, but it becomes even more difficult when the boundary of the quantum mechanical fragment cuts a bond. We have developed a suite of methods for more realistically treating interactions across such boundaries. These methods include redistributing and balancing the external partial atomic charges and the use of tuned fluorine

  4. Fragmentation of atomic clusters: A theoretical study

    International Nuclear Information System (INIS)

    Lopez, M.J.; Jellinek, J.

    1994-01-01

    Collisionless fragmentation of nonrotating model n-atom metal clusters (n=12, 13, and 14) is studied using isoergic molecular-dynamics simulations. Minimum-energy paths for fragmentation are mapped out as functions of the distance between the centers of mass of the fragments. These paths provide information on the fragmentation energies for the different fragmentation channels. Fragmentation patterns (distributions of the fragmentation channel probabilities) and global and channel-specific fragmentation rate constants are computed and analyzed as functions of the internal energy and of the size of the clusters. The trends derived from the dynamics are compared with those obtained using the RRK and TST statistical approaches. The dynamics of the fragmentation process is analyzed in terms of characteristic quantities such as the distance between the centers of mass of the fragments, their relative translational energy, and their interaction energy, all considered as functions of time

  5. Dark matter gravitinos and baryons via Q-ball decay in the gauge-mediated MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Doddato, Francesca; McDonald, John, E-mail: f.doddato@lancaster.ac.uk, E-mail: j.mcdonald@lancaster.ac.uk [Lancaster-Manchester-Sheffield Consortium for Fundamental Physics, Cosmology and Astroparticle Physics Group, Dept. of Physics, University of Lancaster, Lancaster LA1 4YB (United Kingdom)

    2013-07-01

    We show that late Q-ball decay in the MSSM with gauge-mediated SUSY breaking can provide a natural source of non-thermal NLSPs which subsequently decay to gravitino dark matter without violating nucleosynthesis constraints. To show this, we perform a global analysis of Q-ball formation and decay in Affleck-Dine baryogenesis for a d = 6 (u{sup c}d{sup c}d{sup c}){sup 2} flat direction of the gauge-mediated MSSM. A general phenomenological potential for the flat-direction is studied and the Q-ball decay properties are obtained as a function of its parameters. The corresponding gravitino mass necessary to account for dark matter is then determined for the case of stau NLSPs. The decay temperature depends on the charge of the Q-balls, which is determined by the fragmentation of the AD condensate. Different fragmentation scenarios are considered, and the final non-thermal NLSP density from Q-ball decay and NLSP annihilation is determined. Particular care is taken to establish that NLSPs from Q-ball decay become homogeneous and non-relativistic prior to annihilation. The gravitino mass necessary for dark matter is naturally consistent with the theoretical gravitino mass in the gauge-mediation model.

  6. DNA fragmentation in spermatozoa

    DEFF Research Database (Denmark)

    Rex, A S; Aagaard, J.; Fedder, J

    2017-01-01

    Sperm DNA Fragmentation has been extensively studied for more than a decade. In the 1940s the uniqueness of the spermatozoa protein complex which stabilizes the DNA was discovered. In the fifties and sixties, the association between unstable chromatin structure and subfertility was investigated....... In the seventies, the impact of induced DNA damage was investigated. In the 1980s the concept of sperm DNA fragmentation as related to infertility was introduced as well as the first DNA fragmentation test: the Sperm Chromatin Structure Assay (SCSA). The terminal deoxynucleotidyl transferase nick end labelling...... (TUNEL) test followed by others was introduced in the nineties. The association between DNA fragmentation in spermatozoa and pregnancy loss has been extensively investigated spurring the need for a therapeutic tool for these patients. This gave rise to an increased interest in the aetiology of DNA damage...

  7. Photon-hadron fragmentation: theoretical situation

    International Nuclear Information System (INIS)

    Peschanski, R.

    1983-07-01

    Using a selection of new experimental results models of hadronic fragmentation and their phenomenological comparison are presented. Indeed a convenient theory of hadronic fragmentation -for instance based on Q.C.D.- does not exist: low transverse momentum fragmentation involves the badly known hadronic long-range forces. Models should clarify the situation in the prospect of an eventual future theory

  8. Recent progress on perturbative QCD fragmentation functions

    International Nuclear Information System (INIS)

    Cheung, K.

    1995-05-01

    The recent development of perturbative QCD (PQCD) fragmentation functions has strong impact on quarkonium production. I shall summarize B c meson production based on these PQCD fragmentation functions, as well as, the highlights of some recent activities on applying these PQCD fragmentation functions to explain anomalous J/ψ and ψ' production at the Tevatron. Finally, I discuss a fragmentation model based on the PQCD fragmentation functions for heavy quarks fragmenting into heavy-light mesons

  9. Long-term effects of fragmentation and fragment properties on bird species richness in Hawaiian forests

    Science.gov (United States)

    David J. Flaspohler; Christian P. Giardina; Gregory P. Asner; Patrick Hart; Jonathan Price; Cassie Ka’apu Lyons; Xeronimo. Castaneda

    2010-01-01

    Forest fragmentation is a common disturbance affecting biological diversity, yet the impacts of fragmentation on many forest processes remain poorly understood. Forest restoration is likely to be more successful when it proceeds with an understanding of how native and exotic vertebrates utilize forest patches of different size. We used a system of forest fragments...

  10. Mass spectrometry for fragment screening.

    Science.gov (United States)

    Chan, Daniel Shiu-Hin; Whitehouse, Andrew J; Coyne, Anthony G; Abell, Chris

    2017-11-08

    Fragment-based approaches in chemical biology and drug discovery have been widely adopted worldwide in both academia and industry. Fragment hits tend to interact weakly with their targets, necessitating the use of sensitive biophysical techniques to detect their binding. Common fragment screening techniques include differential scanning fluorimetry (DSF) and ligand-observed NMR. Validation and characterization of hits is usually performed using a combination of protein-observed NMR, isothermal titration calorimetry (ITC) and X-ray crystallography. In this context, MS is a relatively underutilized technique in fragment screening for drug discovery. MS-based techniques have the advantage of high sensitivity, low sample consumption and being label-free. This review highlights recent examples of the emerging use of MS-based techniques in fragment screening. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  11. Universal odd-even staggering in isotopic fragmentation and spallation cross sections of neutron-rich fragments

    Science.gov (United States)

    Mei, B.; Tu, X. L.; Wang, M.

    2018-04-01

    An evident odd-even staggering (OES) in fragment cross sections has been experimentally observed in many fragmentation and spallation reactions. However, quantitative comparisons of this OES effect in different reaction systems are still scarce for neutron-rich nuclei near the neutron drip line. By employing a third-order difference formula, the magnitudes of this OES in extensive experimental cross sections are systematically investigated for many neutron-rich nuclei with (N -Z ) from 1 to 23 over a broad range of atomic numbers (Z ≈3 -50 ). A comparison of these magnitude values extracted from fragment cross sections measured in different fragmentation and spallation reactions with a large variety of projectile-target combinations over a wide energy range reveals that the OES magnitude is almost independent of the projectile-target combinations and the projectile energy. The weighted average of these OES magnitudes derived from cross sections accurately measured in different reaction systems is adopted as the evaluation value of the OES magnitude. These evaluated OES magnitudes are recommended to be used in fragmentation and spallation models to improve their predictions for fragment cross sections.

  12. Physics of projectile fragments

    International Nuclear Information System (INIS)

    Minamisono, Tadanori

    1982-01-01

    This is a study report on the polarization phenomena of the projectile fragments produced by heavy ion reactions, and the beta decay of fragments. The experimental project by using heavy ions with the energy from 50 MeV/amu to 250 MeV/amu was designed. Construction of an angle-dispersion spectrograph for projectile fragments was proposed. This is a two-stage spectrograph. The first stage is a QQDQQ type separator, and the second stage is QDQD type. Estimation shows that Co-66 may be separated from the nuclei with mass of 65 and 67. The orientation of fragments can be measured by detecting beta-ray. The apparatus consists of a uniform field magnet, an energy absorber, a stopper, a RF coil and a beta-ray hodoscope. This system can be used for not only this purpose but also for the measurement of hyperfine structure. (Kato, T.)

  13. The mechanism of break-up reactions of light ions at non-relativistic and relativistic energies

    International Nuclear Information System (INIS)

    Baur, G.; Hoffmann, B.; Rosel, F.; Trautmann, D.; Shyam, R.

    1984-01-01

    Fragmentation processes is nuclear collisions are reviewed. The authors consider a three-body model, where a projectile a=b+x interacts with a target nucleus A. The interaction is described by means of optical potentials V/sub Aa/, V/sub Ab/ and V/sub Ax/ respectively. The projectile a is composed of two subsystems b (''spectator'') and x (''participant'') bound together by V/sub bx/

  14. On the nesting biology of Pirhosigma Giordani Soika (Hymenoptera, Vespidae, Eumeninae, with special reference to the use of vegetable matter

    Directory of Open Access Journals (Sweden)

    Marcel G. Hermes

    2013-12-01

    Full Text Available On the nesting biology of Pirhosigma Giordani Soika (Hymenoptera, Vespidae, Eumeninae, with special reference to the use of vegetable matter. The use of vegetable matter in nest building is not widespread among the Eumeninae, and is reported for the first time for the two species of potter wasps Pirhosigma superficiale and P. limpidum. These wasps make mostly spherical mud nests over which they attach small pieces of unmasticated plant matter. Use of plant fragments in this group of wasps is interpreted as camouflage behavior.

  15. MRI of displaced meniscal fragments

    International Nuclear Information System (INIS)

    Dunoski, Brian; Zbojniewicz, Andrew M.; Laor, Tal

    2012-01-01

    A torn meniscus frequently requires surgical fixation or debridement as definitive treatment. Meniscal tears with associated fragment displacement, such as bucket handle and flap tears, can be difficult to recognize and accurately describe on MRI, and displaced fragments can be challenging to identify at surgery. A displaced meniscal fragment can be obscured by synovium or be in a location not usually evaluated at arthroscopy. We present a pictorial essay of meniscal tears with displaced fragments in patients referred to a pediatric hospital in order to increase recognition and accurate interpretation by the radiologist, who in turn can help assist the surgeon in planning appropriate therapy. (orig.)

  16. MRI of displaced meniscal fragments

    Energy Technology Data Exchange (ETDEWEB)

    Dunoski, Brian [University of Cincinnati College of Medicine, Department of Radiology, Cincinnati Children' s Hospital Medical Center, Cincinnati, OH (United States); Children' s Hospital of Michigan, Department of Radiology, Detroit, MI (United States); Zbojniewicz, Andrew M.; Laor, Tal [University of Cincinnati College of Medicine, Department of Radiology, Cincinnati Children' s Hospital Medical Center, Cincinnati, OH (United States)

    2012-01-15

    A torn meniscus frequently requires surgical fixation or debridement as definitive treatment. Meniscal tears with associated fragment displacement, such as bucket handle and flap tears, can be difficult to recognize and accurately describe on MRI, and displaced fragments can be challenging to identify at surgery. A displaced meniscal fragment can be obscured by synovium or be in a location not usually evaluated at arthroscopy. We present a pictorial essay of meniscal tears with displaced fragments in patients referred to a pediatric hospital in order to increase recognition and accurate interpretation by the radiologist, who in turn can help assist the surgeon in planning appropriate therapy. (orig.)

  17. Dimensional crossover in fragmentation

    Science.gov (United States)

    Sotolongo-Costa, Oscar; Rodriguez, Arezky H.; Rodgers, G. J.

    2000-11-01

    Experiments in which thick clay plates and glass rods are fractured have revealed different behavior of fragment mass distribution function in the small and large fragment regions. In this paper we explain this behavior using non-extensive Tsallis statistics and show how the crossover between the two regions is caused by the change in the fragments’ dimensionality during the fracture process. We obtain a physical criterion for the position of this crossover and an expression for the change in the power-law exponent between the small and large fragment regions. These predictions are in good agreement with the experiments on thick clay plates.

  18. Nuclear interactions and hadronic matter

    International Nuclear Information System (INIS)

    Petrovici, Mihai; Pop, Amalia; Stoicea, Gabriel; Berceanu, Ionela; Moisa, Dorin; Petris, Mariana; Simion, Victor; Aiftimiei, Cristina; Cruceru, Ilie; Ciobanu, Mircea; Catanescu, Vasile; Caragheorgheopol; Gheorghe

    2002-01-01

    group had contributions in their design, construction, operation, calibration and data analysis, part of these activities being the subject of our project financed by CERES National Program. CHIMERA being a new detector, for its calibration in energy, charge and mass of the identified particles, quite large efforts were dedicated for developing consistent calibration procedures. Based on these, correct Data Summary Tapes (DST) are currently produced and analysis activities will start in the near future. Concerning the FOPI detector, our group concentrated in extracting detailed information on the collective phenomena in central and mid-central symmetric heavy ion collisions in the energy range of 90 AMeV - 400 AMeV. We shown that such observables are sensitive to the EoS and the comparison with model calculations evidenced that at such energies a soft EoS could explain the observed experimental trends. Another subject followed up by our group is related to the dependence of the squeeze-out phenomena on the N/Z content of the spectator matter. Such studies could be decisive for extracting the in-medium isospin dependence of the nucleon-nucleon cross section. (authors)

  19. Analysis of multi-fragmentation reactions induced by relativistic heavy ions using the statistical multi-fragmentation model

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, T., E-mail: ogawa.tatsuhiko@jaea.go.jp [Research Group for Radiation Protection, Division of Environment and Radiation Sciences, Nuclear Science and Engineering Directorate, Japan Atomic Energy Agency, Shirakata-Shirane, Tokai, Ibaraki 319-1195 (Japan); Sato, T.; Hashimoto, S. [Research Group for Radiation Protection, Division of Environment and Radiation Sciences, Nuclear Science and Engineering Directorate, Japan Atomic Energy Agency, Shirakata-Shirane, Tokai, Ibaraki 319-1195 (Japan); Niita, K. [Research Organization for Information Science and Technology, Shirakata-shirane, Tokai, Ibaraki 319-1188 (Japan)

    2013-09-21

    The fragmentation cross-sections of relativistic energy nucleus–nucleus collisions were analyzed using the statistical multi-fragmentation model (SMM) incorporated with the Monte-Carlo radiation transport simulation code particle and heavy ion transport code system (PHITS). Comparison with the literature data showed that PHITS-SMM reproduces fragmentation cross-sections of heavy nuclei at relativistic energies better than the original PHITS by up to two orders of magnitude. It was also found that SMM does not degrade the neutron production cross-sections in heavy ion collisions or the fragmentation cross-sections of light nuclei, for which SMM has not been benchmarked. Therefore, SMM is a robust model that can supplement conventional nucleus–nucleus reaction models, enabling more accurate prediction of fragmentation cross-sections.

  20. Analysis of multi-fragmentation reactions induced by relativistic heavy ions using the statistical multi-fragmentation model

    International Nuclear Information System (INIS)

    Ogawa, T.; Sato, T.; Hashimoto, S.; Niita, K.

    2013-01-01

    The fragmentation cross-sections of relativistic energy nucleus–nucleus collisions were analyzed using the statistical multi-fragmentation model (SMM) incorporated with the Monte-Carlo radiation transport simulation code particle and heavy ion transport code system (PHITS). Comparison with the literature data showed that PHITS-SMM reproduces fragmentation cross-sections of heavy nuclei at relativistic energies better than the original PHITS by up to two orders of magnitude. It was also found that SMM does not degrade the neutron production cross-sections in heavy ion collisions or the fragmentation cross-sections of light nuclei, for which SMM has not been benchmarked. Therefore, SMM is a robust model that can supplement conventional nucleus–nucleus reaction models, enabling more accurate prediction of fragmentation cross-sections

  1. Fragment-based quantitative structure-activity relationship (FB-QSAR) for fragment-based drug design.

    Science.gov (United States)

    Du, Qi-Shi; Huang, Ri-Bo; Wei, Yu-Tuo; Pang, Zong-Wen; Du, Li-Qin; Chou, Kuo-Chen

    2009-01-30

    In cooperation with the fragment-based design a new drug design method, the so-called "fragment-based quantitative structure-activity relationship" (FB-QSAR) is proposed. The essence of the new method is that the molecular framework in a family of drug candidates are divided into several fragments according to their substitutes being investigated. The bioactivities of molecules are correlated with the physicochemical properties of the molecular fragments through two sets of coefficients in the linear free energy equations. One coefficient set is for the physicochemical properties and the other for the weight factors of the molecular fragments. Meanwhile, an iterative double least square (IDLS) technique is developed to solve the two sets of coefficients in a training data set alternately and iteratively. The IDLS technique is a feedback procedure with machine learning ability. The standard Two-dimensional quantitative structure-activity relationship (2D-QSAR) is a special case, in the FB-QSAR, when the whole molecule is treated as one entity. The FB-QSAR approach can remarkably enhance the predictive power and provide more structural insights into rational drug design. As an example, the FB-QSAR is applied to build a predictive model of neuraminidase inhibitors for drug development against H5N1 influenza virus. (c) 2008 Wiley Periodicals, Inc.

  2. Role of isospin in nuclear-matter liquid-gas phase transition

    International Nuclear Information System (INIS)

    Ducoin, C.

    2006-10-01

    Nuclear matter presents a phase transition of the liquid-gas type. This well-known feature is due to the nuclear interaction profile (mean-range attractive, short-range repulsive). Symmetric-nuclear-matter thermodynamics is thus analogous to that of a Van der Waals fluid. The study shows up to be more complex in the case of asymmetric matter, composed of neutrons and protons in an arbitrary proportion. Isospin, which distinguishes both constituents, gives a measure of this proportion. Studying asymmetric matter, isospin is an additional degree of freedom, which means one more dimension to consider in the space of observables. The nuclear liquid-gas transition is associated with the multi-fragmentation phenomenon observed in heavy-ion collisions, and to compact-star physics: the involved systems are neutron rich, so they are affected by the isospin degree of freedom. The present work is a theoretical study of isospin effects which appear in the asymmetric nuclear matter liquid-gas phase transition. A mean-field approach is used, with a Skyrme nuclear effective interaction. We demonstrate the presence of a first-order phase transition for asymmetric matter, and study the isospin distillation phenomenon associated with this transition. The case of phase separation at thermodynamic equilibrium is compared to spinodal decomposition. Finite size effects are addressed, as well as the influence of the electron gas which is present in the astrophysical context. (author)

  3. Construction and operation of an universal stopping equipment for the fragment separator of the GSI Darmstadt

    International Nuclear Information System (INIS)

    Weckenmann, J.; Hanelt, E.; Schmidt, K.H.

    1990-07-01

    The fragment separator is a magnetic spectrometer, in which an especially-shaped layer of matter is applied as ion-optical element. The energy loss occurring there is accompanied by a series of unwanted effects like nuclear reaction, elecromagnetic dissociation, energy and angle straggling. These effects reduce on the one hand the total resolution of the separator and on the other hand the number of the fragments, which reach the exit of the separator. In the present study it was stated that the influence of these effects exhibits in most of the cases only a weak dependence on the material of the stopper. The ideal stopper material has a mass number, which corresponds nearly to the mass number of the selected fragment. If only one single stopper material will be applied, a material with low mass number seems to be the best compromise. Therefore for the universal stopper equipment of the fragment separator aluminium was selected. A further object of this study was the profile of the stopper. In a symmetrically constructed magnet spectrometer as the fragment separator the highest resolution is then reached, when the required particles are stopped in the whole width of their momentum distribution by a constant factor. This requirement leads to a curved profile of the stopper. It was stated that the profile can be approached by a linear wedge shape without a disadvantageous change of the resolution of the separator. The technical realization of the universal stopping equipment for the fragment separator consists mainly of very accurately manufactured, shiftable, and rotatable wedge-shaped layers. By means of a step-motor guiding the profiles required for the isotope separation can thus be obtained in a wide range. (orig.) [de

  4. Reframing landscape fragmentation's effects on ecosystem services.

    Science.gov (United States)

    Mitchell, Matthew G E; Suarez-Castro, Andrés F; Martinez-Harms, Maria; Maron, Martine; McAlpine, Clive; Gaston, Kevin J; Johansen, Kasper; Rhodes, Jonathan R

    2015-04-01

    Landscape structure and fragmentation have important effects on ecosystem services, with a common assumption being that fragmentation reduces service provision. This is based on fragmentation's expected effects on ecosystem service supply, but ignores how fragmentation influences the flow of services to people. Here we develop a new conceptual framework that explicitly considers the links between landscape fragmentation, the supply of services, and the flow of services to people. We argue that fragmentation's effects on ecosystem service flow can be positive or negative, and use our framework to construct testable hypotheses about the effects of fragmentation on final ecosystem service provision. Empirical efforts to apply and test this framework are critical to improving landscape management for multiple ecosystem services. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Fragment Size Distribution of Blasted Rock Mass

    Science.gov (United States)

    Jug, Jasmin; Strelec, Stjepan; Gazdek, Mario; Kavur, Boris

    2017-12-01

    Rock mass is a heterogeneous material, and the heterogeneity of rock causes sizes distribution of fragmented rocks in blasting. Prediction of blasted rock mass fragmentation has a significant role in the overall economics of opencast mines. Blasting as primary fragmentation can significantly decrease the cost of loading, transport, crushing and milling operations. Blast fragmentation chiefly depends on the specific blast design (geometry of blast holes drilling, the quantity and class of explosive, the blasting form, the timing and partition, etc.) and on the properties of the rock mass (including the uniaxial compressive strength, the rock mass elastic Young modulus, the rock discontinuity characteristics and the rock density). Prediction and processing of blasting results researchers can accomplish by a variety of existing software’s and models, one of them is the Kuz-Ram model, which is possibly the most widely used approach to estimating fragmentation from blasting. This paper shows the estimation of fragmentation using the "SB" program, which was created by the authors. Mentioned program includes the Kuz-Ram model. Models of fragmentation are confirmed and calibrated by comparing the estimated fragmentation with actual post-blast fragmentation from image processing techniques. In this study, the Kuz-Ram fragmentation model has been used for an open-pit limestone quarry in Dalmatia, southern Croatia. The resulting calibrated value of the rock factor enables the quality prognosis of fragmentation in further blasting works, with changed drilling geometry and blast design parameters. It also facilitates simulation in the program to optimize blasting works and get the desired fragmentations of the blasted rock mass.

  6. Measurement of jet fragmentation functions and of their moments in $pp$ collisions at $\\sqrt{s}=2.76$ TeV with ALICE at the LHC

    CERN Document Server

    AUTHOR|(CDS)2074876; Kabana, Sonja; Shabetai, Alexandre; Zhou, Daicui

    A cross-over between ordinary nuclear matter and a state of de-confined quarks and gluons, the Quark Gluon Plasma (QGP), is predicted by lattice QCD calculations at low chemical potential and high temperature in the nuclear phase diagram. Experimentally, ultra-relativistic heavy ion collisions are used to produce and study the hot and dense QGP medium. Produced in a hard scattering at the early stage of the collision a highly energetic parton is first expected to lose energy in the medium before fragmenting into a hadronic spray of particles called jet. A detailed study of the modification of the jet structure and of its fragmentation pattern in vacuum and in medium should provide insights into the QGP properties. The jet fragmentation functions describe the momentum distribution of hadrons inside a reconstructed jet. In proton-proton ($pp$) collisions their measurement is important for understanding the mechanisms of parton fragmentation. Such measurements also provide a test of perturbative Quantum Chro...

  7. Medium-scale melt-sodium fragmentation experiments

    International Nuclear Information System (INIS)

    Chu, T.Y.; Beattie, A.G.; Drotning, W.D.; Powers, D.A.

    1979-01-01

    The results of a series of fragmentation experiments involving up to 20 Kg of thermitically produced high temperature melts and 23 Kg of sodium are presented. Except for one experiment where some centimeter size particles are observed, the fragment distributions seem to be in the range of previous data. Spatial distribution of the fragments in the debris bed appears to be stratified. Scanning electron micrographs of fragments indicate fragmentation to be occurring in the molten state for the more intense interactions observed. Interaction data obtained show quiescent periods of 0.5 to 1.5 second between pressure pulses. The force impulse values per unit mass of melt seems to be in the same range as previous experiments

  8. Dual Fragment Impact of PBX Charges

    Science.gov (United States)

    Haskins, Peter; Briggs, Richard; Leeming, David; White, Nathan; Cheese, Philip; DE&S MoD UK Team; Ordnance Test Solutions Ltd Team

    2017-06-01

    Fragment impact can pose a significant hazard to many systems containing explosives or propellants. Testing for this threat is most commonly carried out using a single fragment. However, it can be argued that an initial fragment strike (or strikes) could sensitise the energetic material to subsequent impacts, which may then lead to a more violent reaction than would have been predicted based upon single fragment studies. To explore this potential hazard we have developed the capability to launch 2 fragments from the same gun at a range of velocities, and achieve impacts on an acceptor charge with good control over the spatial and temporal separation of the strikes. In this paper we will describe in detail the experimental techniques we have used, both to achieve the dual fragment launch and observe the acceptor charge response. In addition, we will describe the results obtained against PBX filled explosive targets; discuss the mechanisms controlling the target response and their significance for vulnerability assessment. Results of these tests have clearly indicated the potential for detonation upon the second strike, at velocities well below those needed for shock initiation by a single fragment.

  9. Fragmentation of massive dense cores down to ≲ 1000 AU: Relation between fragmentation and density structure

    International Nuclear Information System (INIS)

    Palau, Aina; Girart, Josep M.; Estalella, Robert; Fuente, Asunción; Fontani, Francesco; Sánchez-Monge, Álvaro; Commerçon, Benoit; Hennebelle, Patrick; Busquet, Gemma; Bontemps, Sylvain; Zapata, Luis A.; Zhang, Qizhou; Di Francesco, James

    2014-01-01

    In order to shed light on the main physical processes controlling fragmentation of massive dense cores, we present a uniform study of the density structure of 19 massive dense cores, selected to be at similar evolutionary stages, for which their relative fragmentation level was assessed in a previous work. We inferred the density structure of the 19 cores through a simultaneous fit of the radial intensity profiles at 450 and 850 μm (or 1.2 mm in two cases) and the spectral energy distribution, assuming spherical symmetry and that the density and temperature of the cores decrease with radius following power-laws. Even though the estimated fragmentation level is strictly speaking a lower limit, its relative value is significant and several trends could be explored with our data. We find a weak (inverse) trend of fragmentation level and density power-law index, with steeper density profiles tending to show lower fragmentation, and vice versa. In addition, we find a trend of fragmentation increasing with density within a given radius, which arises from a combination of flat density profile and high central density and is consistent with Jeans fragmentation. We considered the effects of rotational-to-gravitational energy ratio, non-thermal velocity dispersion, and turbulence mode on the density structure of the cores, and found that compressive turbulence seems to yield higher central densities. Finally, a possible explanation for the origin of cores with concentrated density profiles, which are the cores showing no fragmentation, could be related with a strong magnetic field, consistent with the outcome of radiation magnetohydrodynamic simulations.

  10. Fragmentation of massive dense cores down to ≲ 1000 AU: Relation between fragmentation and density structure

    Energy Technology Data Exchange (ETDEWEB)

    Palau, Aina; Girart, Josep M. [Institut de Ciències de l' Espai (CSIC-IEEC), Campus UAB-Facultat de Ciències, Torre C5-parell 2, E-08193 Bellaterra, Catalunya (Spain); Estalella, Robert [Departament d' Astronomia i Meteorologia (IEEC-UB), Institut de Ciències del Cosmos, Universitat de Barcelona, Martí i Franquès, 1, E-08028 Barcelona (Spain); Fuente, Asunción [Observatorio Astronómico Nacional, P.O. Box 112, E-28803 Alcalá de Henares, Madrid (Spain); Fontani, Francesco; Sánchez-Monge, Álvaro [Osservatorio Astrofisico di Arcetri, INAF, Lago E. Fermi 5, I-50125 Firenze (Italy); Commerçon, Benoit; Hennebelle, Patrick [Laboratoire de Radioastronomie, UMR CNRS 8112, École Normale Supérieure et Observatoire de Paris, 24 rue Lhomond, F-75231 Paris Cedex 05 (France); Busquet, Gemma [INAF-Istituto di Astrofisica e Planetologia Spaziali, Area di Recerca di Tor Vergata, Via Fosso Cavaliere 100, I-00133 Roma (Italy); Bontemps, Sylvain [Université de Bordeaux, LAB, UMR 5804, F-33270 Floirac (France); Zapata, Luis A. [Centro de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, P.O. Box 3-72, 58090 Morelia, Michoacán (Mexico); Zhang, Qizhou [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Di Francesco, James, E-mail: palau@ieec.uab.es [Department of Physics and Astronomy, University of Victoria, P.O. Box 355, STN CSC, Victoria, BC, V8W 3P6 (Canada)

    2014-04-10

    In order to shed light on the main physical processes controlling fragmentation of massive dense cores, we present a uniform study of the density structure of 19 massive dense cores, selected to be at similar evolutionary stages, for which their relative fragmentation level was assessed in a previous work. We inferred the density structure of the 19 cores through a simultaneous fit of the radial intensity profiles at 450 and 850 μm (or 1.2 mm in two cases) and the spectral energy distribution, assuming spherical symmetry and that the density and temperature of the cores decrease with radius following power-laws. Even though the estimated fragmentation level is strictly speaking a lower limit, its relative value is significant and several trends could be explored with our data. We find a weak (inverse) trend of fragmentation level and density power-law index, with steeper density profiles tending to show lower fragmentation, and vice versa. In addition, we find a trend of fragmentation increasing with density within a given radius, which arises from a combination of flat density profile and high central density and is consistent with Jeans fragmentation. We considered the effects of rotational-to-gravitational energy ratio, non-thermal velocity dispersion, and turbulence mode on the density structure of the cores, and found that compressive turbulence seems to yield higher central densities. Finally, a possible explanation for the origin of cores with concentrated density profiles, which are the cores showing no fragmentation, could be related with a strong magnetic field, consistent with the outcome of radiation magnetohydrodynamic simulations.

  11. Gallstone fragmentation by control electrohydraulic lithotripsy

    International Nuclear Information System (INIS)

    Tung, G.A.; Mueller, P.R.; Brink, J.A.; Saini, S.; Picus, D.; Simeone, J.F.; Ferrucci, J.T.

    1989-01-01

    The authors have performed in vitro contact electrohydraulic lithotripsy (EHL) of 100 gallstones > 10 mm in diameter to identify physical and technical factors that affect fragmentation success. Ninety-one of 100 stones were fragmented with a 3-F electrode (average, seven shocks; range, 1--42); only 12 stones were fragmented with a single shock. Of the nine stones refractory to 50 shocks, four were > 30 mm in diameter and five stones were densely calcified. The most important variable determining power requirements for fragmentation was gallstone size (R = .58), but radiographic calcification of gallstones was also important (R = .47). Stones < 15 mm tended to produce fragments of left-angle 2 mm; stones right-angle 20 mm tended to produce two to five large discrete fragments (P , .05). In addition, lithotripsy could be conducted equally well in 1:1 dilute diatrizoate contrast agent as in 1:6 normal saline, suggesting that contact EHL could be performed under fluoroscopy

  12. Fragmentation functions approach in pQCD fragmentation phenomena

    International Nuclear Information System (INIS)

    Rolli, S.

    1996-07-01

    Next-to-leading order parton fragmentation functions into light mesons are presented. They have been extracted from real and simulated e + e - data and used to predict inclusive single particle distributions at different machines

  13. Fragmentation of neck-like structures

    International Nuclear Information System (INIS)

    Montoya, C.; Bowman, D.R.; Peaslee, G.F.; Michigan State Univ., East Lansing, MI

    1994-01-01

    Evidence for intermediate mass fragment emission from neck-like structures joining projectile- and target-like residues has been observed for peripheral 129 Xe+ nat Cu collisions at E/A=50 MeV. These framents are emitted primarily at velocities intermediate between those of the projectile and the target. Relative to the charge distribution for fragments evaporated from the projectile-like residue, the distribution for ''neck'' emission shows an enhanced emission for fragments with 4 f < 8. (orig.)

  14. Determination of the shapes and sizes of the regions in which in hadron-nucleus collisions reactions leading to the nucleon emission, particle production, and fragment evaporation occur

    International Nuclear Information System (INIS)

    Strugalski, Z.

    1985-01-01

    Shapes and sizes of the regions in target-nuclei in which reactions leading to the nucleon emission, particle production and fragment evaporation occur are determined. The region of nucleon emission is of cylindrical shape, with the diameter as large as two nucleon diameters, centered on the incident hadron course. The reactions leading to the particle production happen predominantly along the incident hadron course in nuclear matter. The fragment evaporation goes from the surface layer of the part of the target-nucleus damaged in nucleon emission process

  15. Forest Fragments Surrounded by Sugar Cane Are More Inhospitable to Terrestrial Amphibian Abundance Than Fragments Surrounded by Pasture

    Directory of Open Access Journals (Sweden)

    Paula Eveline Ribeiro D’Anunciação

    2013-01-01

    Full Text Available In recent years, there has been increasing interest in matrix-type influence on forest fragments. Terrestrial amphibians are good bioindicators for this kind of research because of low vagility and high philopatry. This study compared richness, abundance, and species composition of terrestrial amphibians through pitfall traps in two sets of semideciduous seasonal forest fragments in southeastern Brazil, according to the predominant surrounding matrix (sugar cane and pasture. There were no differences in richness, but fragments surrounded by sugar cane had the lowest abundance of amphibians, whereas fragments surrounded by pastures had greater abundance. The most abundant species, Rhinella ornata, showed no biometric differences between fragment groups but like many other amphibians sampled showed very low numbers of individuals in fragments dominated by sugar cane fields. Our data indicate that the sugar cane matrix negatively influences the community of amphibians present in fragments surrounded by this type of land use.

  16. Fragmentation of Ceramics in Rapid Expansion Mode

    Science.gov (United States)

    Maiti, Spandan; Geubelle, Philippe H.; Rangaswamy, Krishnan

    The study of the fragmentation process goes back to more than a century, motivated primarily by problems related to mining and ore handling (Grady and Kipp, 1985). Various theories have been proposed to predict the fragmentation stress and the fragment size and distribution. But the investigations are generally case specific and relate to only a narrow set of fragmentation processes. A number of theoretical studies of dynamic fragmentation in a rapidly expanding body can be found in the literature. For example, the study summarized in (Grady, 1982) presents a model based on a simple energy balance concept between the surface energy released due to fracture and the kinetic energy of the fragments. Subsequent refinements of the energy balance model have been proposed by (Glenn and Chudnovsky, 1986), which take into account the strain energy of the fragments and specify a threshold stress below which no fragmentation occurs. These models assume that the fracture events are instantaneous and occur simultaneously. Evidently, these assumptions are quite restrictive and these models can not take into account the transient nature of the fragmentation process after the onset of fracture in the material. A more recent model proposed by (Miller et al., 1999) however takes into account this time-dependent nature of the fragmentation event and the distribution of flaws of various strengths in the original material.

  17. Percolation versus microcanonical fragmentation - comparison of fragment size distribution: Where is the liquid-gas transition in nuclei?

    International Nuclear Information System (INIS)

    Jaqaman, H.R.; Birzeit Univ.; Papp, G.; Eoetvoes Lorand Tudomanyegyetem, Budapest; Gross, D.H.E.; Freie Univ. Berlin

    1990-01-01

    The distributions of fragments produced by microcanonical multifragmentation of hot nuclei are compared with the cluster distributions predicted by a bond percolation model on a finite lattice. The conditional moments of these distributions are used together with the correlations between the largest three fragments in each event. Whereas percolation and statistical nuclear fragmentation agree in many details as in the usual plots of the averaged moments of the fragment distributions which yield the critical exponents, they turn out to be essentially different when less averaged quantities or correlations are considered. The differences between the predictions of the two models are mainly due to the particularities of the nuclear problem, especially the effect of the long-range Coulomb force which favours the break-up of the highly excited nucleus into two large fragments (pseudo-fission) and, to a somewhat lesser extent, enhances the possibility for the cracking of the nucleus into more than two large fragments. The fission events are, however, clearly separated from a second branch of critical correlations which shows up clearly in both nuclear fragmentation and percolation. We think that this critical correlation branch is due to the liquid-gas phase transition in finite nuclei. (orig.)

  18. Affective telepathy, or the intuition of the heart: 'Persona' with 'Mulholland Drive'

    NARCIS (Netherlands)

    Laine, T.

    2009-01-01

    This paper investigates the affective dynamism of the cinematic experience in terms of the so-called intuition of the heart. Inspired by the writings of Jean-Luc Nancy, it shows how the affective circulation between the film and the spectator can be a matter of sharing rather than a consequence of

  19. The formation of planets by disc fragmentation

    Directory of Open Access Journals (Sweden)

    Stamatellos Dimitris

    2013-04-01

    Full Text Available I discuss the role that disc fragmentation plays in the formation of gas giant and terrestrial planets, and how this relates to the formation of brown dwarfs and low-mass stars, and ultimately to the process of star formation. Protostellar discs may fragment, if they are massive enough and can cool fast enough, but most of the objects that form by fragmentation are brown dwarfs. It may be possible that planets also form, if the mass growth of a proto-fragment is stopped (e.g. if this fragment is ejected from the disc, or suppressed and even reversed (e.g by tidal stripping. I will discuss if it is possible to distinguish whether a planet has formed by disc fragmentation or core accretion, and mention of a few examples of observed exoplanets that are suggestive of formation by disc fragmentation.

  20. Extraction of 16th Century Calender Fragments

    DEFF Research Database (Denmark)

    Holck, Jakob Povl; Etheridge, Christian

    at the Cultural Heritage & Archaeometric Research Team, SDU. Upon finding medieval manuscript fragments in the university library’s special collections, scholars at the Centre for Medieval Literature are consulted. In most cases, digital pictures of the finds will circulate in the international community...... fragments may require extensive use of Big Data and other forms of analysis in order to be identified. Usually, the university library prefers not to remove the fragments from their “fragment carriers”. In order to read fragments that are only partially visible or invisible, x-ray technology may be deployed...... of medieval scholars. Thousands of 16th and 17th Century books are stored in the University Library of Southern Denmark. One out of five of these books is expected to contain medieval manuscript fragments or fragments of rare prints, e.g. incunabula....

  1. Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products.

    Science.gov (United States)

    Prescher, Horst; Koch, Guido; Schuhmann, Tim; Ertl, Peter; Bussenault, Alex; Glick, Meir; Dix, Ina; Petersen, Frank; Lizos, Dimitrios E

    2017-02-01

    A fragment library consisting of 3D-shaped, natural product-like fragments was assembled. Library construction was mainly performed by natural product degradation and natural product diversification reactions and was complemented by the identification of 3D-shaped, natural product like fragments available from commercial sources. In addition, during the course of these studies, novel rearrangements were discovered for Massarigenin C and Cytochalasin E. The obtained fragment library has an excellent 3D-shape and natural product likeness, covering a novel, unexplored and underrepresented chemical space in fragment based drug discovery (FBDD). Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Fluctuations in the fragmentation process

    International Nuclear Information System (INIS)

    Botet, R.; Ploszajczak, M.

    1993-01-01

    Some general framework of sequential fragmentation is presented, as provided by the newly proposed Fragmentation - Inactivation - Binary model, and to study briefly its basic and universal features. This model includes as particular cases most of the previous kinetic fragmentation models. In particular it is discussed how one arrives in this framework to the critical behaviour, called the shattering transition. This model is then compared to recent data on gold multifragmentation at 600 MeV/nucl. (authors) 20 refs., 5 figs

  3. The spectroscopy of fission fragments

    International Nuclear Information System (INIS)

    Phillips, W.R.

    1998-01-01

    High-resolution measurements on γ rays from fission fragments have provided a rich source of information, unobtainable at the moment in any other way, on the spectroscopy of neutron-rich nuclei. In recent years important data have been obtained on the yrast- and near yrast-structure of neutron-rich fission fragments. We discuss the scope of measurements which can be made on prompt gamma rays from secondary fission fragments, the techniques used in the experiments and some results recently obtained. (author)

  4. Senekos dramų herojų jausmų raiška ir poveikis žiūrovams. Expression of the feelings of the characters and impact on the spectators in Seneca’s dramas

    Directory of Open Access Journals (Sweden)

    Jovita Dikmonienė

    2008-01-01

    Full Text Available On the basis of the works by Taplin, Nussbaum, and Schiesar, the article explores the feelings of the protagonists of Seneca’s tragedies, Thyestes and Medea, which are the factors that develop the plot and the dynamics of the tragedies. The article also reviews the emotions these tragedies may set up in the spectators and readers. A comparison is draw between these tragedies and three philosophical dialogues of Seneca On Anger. The article investigates why and how the hatred and fury of the protagonists grows and develops. Anger is shown as pain by Seneca. Such words as ira and dolor are used as synonyms in the tragedies. The protagonists’ emotions of anger and rage cause the spectators’ fear.In Thyestes and Medea, very much like in his philosophical piece On Anger, Seneca discloses the feeling of anger of the main characters in three stages. In the first stage, the poet depicts involuntary anger of Medea with Jason who has broken the vows of love. In Thyestes, Atreus is angry with Thyestes who has insulted his glory. In stages one and three the characters talk to their spirit and the feeling of anger as if with an ostensible, imaginable interlocutor. In stage two, Seneca discloses extensive pride of the protagonists, the feeling of anger that is managed and controlled, their accusations to the offenders, and their wilful determination to revenge. In stage three, the poet depicts wild and uncontrollable anger and fury when Medea and Atreus kill children not because of any need, but because the passion of anger blinds the wisdom. The first and third stages of anger are shown by Seneca as uncontrollable and unconscious, whereas the second stage of anger – a conscious when the protagonists can control their passions, yet they succumb to them.In the tragedies, like in the essay On Anger, Seneca focuses on the depiction of the consequences of anger and the damage that the failure to control anger in due time brings to a man and the people

  5. [Fragment-based drug discovery: concept and aim].

    Science.gov (United States)

    Tanaka, Daisuke

    2010-03-01

    Fragment-Based Drug Discovery (FBDD) has been recognized as a newly emerging lead discovery methodology that involves biophysical fragment screening and chemistry-driven fragment-to-lead stages. Although fragments, defined as structurally simple and small compounds (typically FBDD primarily turns our attention to weakly but specifically binding fragments (hit fragments) as the starting point of medicinal chemistry. Hit fragments are then promoted to more potent lead compounds through linking or merging with another hit fragment and/or attaching functional groups. Another positive aspect of FBDD is ligand efficiency. Ligand efficiency is a useful guide in screening hit selection and hit-to-lead phases to achieve lead-likeness. Owing to these features, a number of successful applications of FBDD to "undruggable targets" (where HTS and other lead identification methods failed to identify useful lead compounds) have been reported. As a result, FBDD is now expected to complement more conventional methodologies. This review, as an introduction of the following articles, will summarize the fundamental concepts of FBDD and will discuss its advantages over other conventional drug discovery approaches.

  6. Velocity distribution of fragments of catastrophic impacts

    Science.gov (United States)

    Takagi, Yasuhiko; Kato, Manabu; Mizutani, Hitoshi

    1992-01-01

    Three dimensional velocities of fragments produced by laboratory impact experiments were measured for basalts and pyrophyllites. The velocity distribution of fragments obtained shows that the velocity range of the major fragments is rather narrow, at most within a factor of 3 and that no clear dependence of velocity on the fragment mass is observed. The NonDimensional Impact Stress (NDIS) defined by Mizutani et al. (1990) is found to be an appropriate scaling parameter to describe the overall fragment velocity as well as the antipodal velocity.

  7. Fragmentation in DNA double-strand breaks

    International Nuclear Information System (INIS)

    Wei Zhiyong; Suzhou Univ., Suzhou; Zhang Lihui; Li Ming; Fan Wo; Xu Yujie

    2005-01-01

    DNA double strand breaks are important lesions induced by irradiations. Random breakage model or quantification supported by this concept is suitable to analyze DNA double strand break data induced by low LET radiation, but deviation from random breakage model is more evident in high LET radiation data analysis. In this work we develop a new method, statistical fragmentation model, to analyze the fragmentation process of DNA double strand breaks. After charged particles enter the biological cell, they produce ionizations along their tracks, and transfer their energies to the cells and break the cellular DNA strands into fragments. The probable distribution of the fragments is obtained under the condition in which the entropy is maximum. Under the approximation E≅E 0 + E 1 l + E 2 l 2 , the distribution functions are obtained as exp(αl + βl 2 ). There are two components, the one proportional to exp(βl 2 ), mainly contributes to the low mass fragment yields, the other component, proportional to exp(αl), decreases slowly as the mass of the fragments increases. Numerical solution of the constraint equations provides parameters α and β. Experimental data, especially when the energy deposition is higher, support the statistical fragmentation model. (authors)

  8. Fission fragment yields from heavy-ion-induced reactions measured with a fragment separator

    Science.gov (United States)

    Tarasov, O. B.; Delaune, O.; Farget, F.; Morrissey, D. J.; Amthor, A. M.; Bastin, B.; Bazin, D.; Blank, B.; Cacéres, L.; Chbihi, A.; Fernández-Dominguez, B.; Grévy, S.; Kamalou, O.; Lukyanov, S. M.; Mittig, W.; Pereira, J.; Perrot, L.; Saint-Laurent, M.-G.; Savajols, H.; Sherrill, B. M.; Stodel, C.; Thomas, J. C.; Villari, A. C.

    2018-04-01

    The systematic study of fission fragment yields under different initial conditions has provided valuable experimental data for benchmarking models of fission product yields. Nuclear reactions using inverse kinematics coupled to the use of a high-resolution spectrometer with good fragment identification are shown here to be a powerful tool to measure the inclusive isotopic yields of fission fragments. In-flight fusion-fission was used in this work to produce secondary beams of neutron-rich isotopes in the collisions of a 238U beam at 24 MeV/u with 9Be and 12C targets at GANIL using the LISE3 fragment separator. Unique identification of the A, Z, and atomic charge state, q, of fission products was attained with the Δ E- TKE-B ρ- ToF measurement technique. Mass, and atomic number distributions are reported for the two reactions. The results show the importance of different reaction mechanisms in the two cases. The optimal target material for higher yields of neutron-rich high- Z isotopes produced in fusion-fission reactions as a function of projectile energy is discussed.

  9. A Study of Quark Fragmentation Using Kaons Produced in Association with Prompt $D_s^±/D^±$ Mesons

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Niharika Ranjan [Purdue Univ., West Lafayette, IN (United States)

    2012-01-01

    Quarks are considered to be the fundamental constituents of hadronic matter, but they have never been observed as free particles. When quarks are produced at high energy colliders, they quickly form bound colorless states, which then decay to produce the particles observed in experiments. The process by which an initially free quark combines with other quarks to form a hadronic particle is called quark fragmentation and has been described using phenomenological models since quarks were first proposed. Since then, several models have been developed to describe the quark fragmentation phenomenon, and these have been tuned to reproduce many average properties of hadrons produced in high energy collisions. In this dissertation, we describe an analysis that probes the properties of particles produced in association with a hadron containing a charm quark that provides a way, for the first time, to study what is thought of as the second particle produced in the process of heavy quar k fragmentation. Data from proton anti-proton collisions was used to carry out this research, which were collected with the CDF II detector at the Fermilab Tevatron and corresponds to 360/pb-1 of integrated luminosity. We reconstruct $D_s^±$ and $D^±$ mesons, which contain charm quarks, and identify the kaons produced in association with them. The kinematic properties of these kaons are compared with predictions of the fragmentation models implemented in the PYTHIA and HERWIG event generators. We find that kaon production in association with $D_s^±$ mesons is enhanced at levels that are in agreement with the fragmentation models but observe differences in production rates of kaons that are produced later in the fragmentation process.

  10. Current fragmentation in deep inelastic scattering

    International Nuclear Information System (INIS)

    Hamer, C.J.

    1975-04-01

    It is argued that the current fragmentation products in deep inelastic electron scattering will not be distributed in a 'one-dimensional' rapidity plateau as in the parton model picture of Feynman and Bjorken. A reaction mechanism with a multiperipheral topology, but which the above configuration might have been achieved, does not in fact populate the current fragmentation plateau; and unless partons are actually observed in the final state, it cannot lead to Bjorken scaling. The basic reason for this failure is shown to be the fact that when a particle is produced in the current fragmentation plateau, the adjacent momentum transfer in the multiperipheral chain becomes large and negative: such processes are inevitably suppressed. Instead, the current fragmentation products are likely to be generated by a fragmentation, or sequential decay process. (author)

  11. Fragment emission from modestly excited nuclear systems

    Energy Technology Data Exchange (ETDEWEB)

    Lou, Y. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Souza, R.T. de [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Chen, S.L. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Cornell, E.W. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Davin, B. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Fox, D. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Hamilton, T.M. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Mcdonald, K. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility; Tsang, M.B. [Michigan State Univ., East Lansing, MI (United States). National Superconducting Cyclotron Lab.; Glasmacher, T. [Michigan State Univ., East Lansing, MI (United States). National Superconducting Cyclotron Lab.; Dinius, J. [Michigan State Univ., East Lansing, MI (United States). National Superconducting Cyclotron Lab.; Gelbke, C.K. [Michigan State Univ., East Lansing, MI (United States). National Superconducting Cyclotron Lab.; Handzy, D.O. [Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry]|[Indiana Univ., Bloomington, IN (United States). Cyclotron Facility]|[Michigan State Univ., East Lansing, MI (United States). National Superconducting Cyclotron Lab.; Hsi, W.C.

    1996-07-08

    Fragment emission patterns occurring in nuclear systems of modest excitation are studied. Exclusive measurement of fragment emission in {sup 14}N+{sup 197}Au reactions at E/A=100, 130 and 156 MeV allows selection of central collisions where a single source dominates the decay. Low threshold measurement of IMF emission for these events allows investigation of the influence of detector threshold effects. The time scale of fragment emission is deduced using fragment-fragment velocity correlations. Comparisons are made to the predictions of a statistical decay model. (orig.).

  12. The spectroscopy of fission fragments

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, W.R. [Department of Physics and Astronomy, University of Manchester, Manchester, M13 9PL (United Kingdom); Collaboration: La Direction des Sciences de la Matiere du CEA (FR); Le Fonds National de la Recherche Scientifique de Belgique (BE)

    1998-12-31

    High-resolution measurements on {gamma} rays from fission fragments have provided a rich source of information, unobtainable at the moment in any other way, on the spectroscopy of neutron-rich nuclei. In recent years important data have been obtained on the yrast- and near yrast-structure of neutron-rich fission fragments. We discuss the scope of measurements which can be made on prompt gamma rays from secondary fission fragments, the techniques used in the experiments and some results recently obtained. (author) 24 refs., 8 figs., 1 tab.

  13. Endovascular Removal of Fractured Inferior Vena Cava Filter Fragments: 5-Year Registry Data with Prospective Outcomes on Retained Fragments.

    Science.gov (United States)

    Kesselman, Andrew J; Hoang, Nam Sao; Sheu, Alexander Y; Kuo, William T

    2018-06-01

    To evaluate the safety and efficacy of attempted percutaneous filter fragment removal during retrieval of fractured inferior vena cava (IVC) filters and to report outcomes associated with retained filter fragments. Over a 5-year period, 82 consecutive patients presenting with a fractured IVC filter were prospectively enrolled into an institutional review board-approved registry. There were 27 men and 55 women (mean, 47 y; range, 19-85 y). After main filter removal, percutaneous removal of fragments was attempted if they were deemed intravascular and accessible on preprocedural computed tomography (CT), cone-beam CT, and/or intravascular ultrasound; distal pulmonary artery (PA) fragments were left alone. A total of 185 fragments were identified (81 IVC, 33 PA, 16 cardiac, 2 hepatic vein, 1 renal vein, 1 aorta, 51 retroperitoneal). Mean filter dwell time was 2,183 days (range, 59-9,936 d). Eighty-seven of 185 fragments (47%) were deemed amenable to attempted removal: 65 IVC, 11 PA, 8 cardiac, 2 hepatic, and 1 aortic. Primary safety outcomes were major procedure-related complications. Fragment removal was successful in 78 of 87 cases (89.7%; 95% confidence interval [CI], 81.3-95.2). There were 6 minor complications with no consequence (6.9%; 95% CI, 2.6-14.4) involving intraprocedural fragment embolization and 1 major complication (1.1%; 95% CI, 0.0-6.2), a cardiac tamponade that was successfully treated. The complication rate from attempted cardiac fragment removal was 12.5% (1 of 8; 95% CI, 0.3-52.7). Among patients with retained cardiopulmonary fragments (n = 19), 81% remained asymptomatic during long-term clinical follow-up of 845 days (range, 386-2,071 d). Percutaneous removal of filter fragments from the IVC and proximal PAs is safe and effective overall, but attempted intracardiac fragment removal carries a higher risk of complication. Most residual filter fragments not amenable to percutaneous removal remain asymptomatic and may be monitored clinically

  14. Fragment Length of Circulating Tumor DNA.

    Science.gov (United States)

    Underhill, Hunter R; Kitzman, Jacob O; Hellwig, Sabine; Welker, Noah C; Daza, Riza; Baker, Daniel N; Gligorich, Keith M; Rostomily, Robert C; Bronner, Mary P; Shendure, Jay

    2016-07-01

    Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and evaluate response to therapy solely through a non-invasive blood draw. However, detecting ctDNA against the normally occurring background of cell-free DNA derived from healthy cells has proven challenging, particularly in non-metastatic solid tumors. In this study, distinct differences in fragment length size between ctDNAs and normal cell-free DNA are defined. Human ctDNA in rat plasma derived from human glioblastoma multiforme stem-like cells in the rat brain and human hepatocellular carcinoma in the rat flank were found to have a shorter principal fragment length than the background rat cell-free DNA (134-144 bp vs. 167 bp, respectively). Subsequently, a similar shift in the fragment length of ctDNA in humans with melanoma and lung cancer was identified compared to healthy controls. Comparison of fragment lengths from cell-free DNA between a melanoma patient and healthy controls found that the BRAF V600E mutant allele occurred more commonly at a shorter fragment length than the fragment length of the wild-type allele (132-145 bp vs. 165 bp, respectively). Moreover, size-selecting for shorter cell-free DNA fragment lengths substantially increased the EGFR T790M mutant allele frequency in human lung cancer. These findings provide compelling evidence that experimental or bioinformatic isolation of a specific subset of fragment lengths from cell-free DNA may improve detection of ctDNA.

  15. Fragger: a protein fragment picker for structural queries.

    Science.gov (United States)

    Berenger, Francois; Simoncini, David; Voet, Arnout; Shrestha, Rojan; Zhang, Kam Y J

    2017-01-01

    Protein modeling and design activities often require querying the Protein Data Bank (PDB) with a structural fragment, possibly containing gaps. For some applications, it is preferable to work on a specific subset of the PDB or with unpublished structures. These requirements, along with specific user needs, motivated the creation of a new software to manage and query 3D protein fragments. Fragger is a protein fragment picker that allows protein fragment databases to be created and queried. All fragment lengths are supported and any set of PDB files can be used to create a database. Fragger can efficiently search a fragment database with a query fragment and a distance threshold. Matching fragments are ranked by distance to the query. The query fragment can have structural gaps and the allowed amino acid sequences matching a query can be constrained via a regular expression of one-letter amino acid codes. Fragger also incorporates a tool to compute the backbone RMSD of one versus many fragments in high throughput. Fragger should be useful for protein design, loop grafting and related structural bioinformatics tasks.

  16. Kaon fragmentation function from NJL-jet model

    International Nuclear Information System (INIS)

    Matevosyan, Hrayr H.; Thomas, Anthony W.; Bentz, Wolfgang

    2010-01-01

    The NJL-jet model provides a sound framework for calculating the fragmentation functions in an effective chiral quark theory, where the momentum and isospin sum rules are satisfied without the introduction of ad hoc parameters [1]. Earlier studies of the pion fragmentation functions using the Nambu-Jona-Lasinio (NJL) model within this framework showed good qualitative agreement with the empirical parameterizations. Here we extend the NJL-jet model by including the strange quark. The corrections to the pion fragmentation function and corresponding kaon fragmentation functions are calculated using the elementary quark to quark-meson fragmentation functions from NJL. The results for the kaon fragmentation function exhibit a qualitative agreement with the empirical parameterizations, while the unfavored strange quark fragmentation to pions is shown to be of the same order of magnitude as the unfavored light quark's. The results of these studies are expected to provide important guidance for the analysis of a large variety of semi-inclusive data.

  17. Fragmentation of rotating protostellar clouds

    International Nuclear Information System (INIS)

    Tohline, J.E.

    1980-01-01

    We examine, with a three-dimensional hydrodynamic computer code, the behavior of rotating, isothermal gas clouds as they collapse from Jeans unstable configurations, in order to determine whether they are susceptible to fragmentation during the initial dynamic collapse phase of their evolution. We find that a gas cloud will not fragment unless (a) it begins collapsing from a radius much smaller than the Jeans radius (i.e., the cloud initially encloses many Jeans masses) and (b) irregularities in the cloud's initial structure (specifically, density inhomogeneities) enclose more than one Jeans mass of material. Gas pressure smooths out features that are not initially Jeans unstable while rotation plays no direct role in damping inhomogeneities. Instead of fragmenting, most of our models collapse to a ring configuration (as has been observed by other investigators in two-dimensional, axisymmetric models). The rings appear to be less susceptible to gragmentation from arbitrary perturbations in their structure than has previously been indicated in other work. Because our models, which include the effects of gas pressure, do not readily fragment during a phase of dynamic collapse, we suggest that gas clouds in the galactic disk undergo fragmentation only during quasi-equilibrium phases of their evolution

  18. Fragment-based approaches to TB drugs.

    Science.gov (United States)

    Marchetti, Chiara; Chan, Daniel S H; Coyne, Anthony G; Abell, Chris

    2018-02-01

    Tuberculosis is an infectious disease associated with significant mortality and morbidity worldwide, particularly in developing countries. The rise of antibiotic resistance in Mycobacterium tuberculosis (Mtb) urgently demands the development of new drug leads to tackle resistant strains. Fragment-based methods have recently emerged at the forefront of pharmaceutical development as a means to generate more effective lead structures, via the identification of fragment molecules that form weak but high quality interactions with the target biomolecule and subsequent fragment optimization. This review highlights a number of novel inhibitors of Mtb targets that have been developed through fragment-based approaches in recent years.

  19. Plasma wake and nuclear forces on fragmented H{sub {sup +}} transport

    Energy Technology Data Exchange (ETDEWEB)

    Barriga-Carrasco, Manuel D [E.T.S.I. Industriales, Universidad de Castilla-La Mancha, E-13071 Ciudad Real (Spain); Deutsch, Claude [Laboratoire de Physique des Gaz et des Plasmas, UMR-8578, Bat. 210, Universite Paris XI, F-91405 Orsay (France)

    2006-12-15

    The objective of the present work is to study the target electronic and nuclear interactions produced when a H{sub {sup +}} ion traverses classical plasma matter. Electronic interactions are treated by means of the dielectric formalism while nuclear interactions are dealt within the classical dispersion theory through a Monte Carlo computer code. The interactions through plasma electronic medium among close ions are called wake forces. We checked that these forces screen the Coulomb explosions of the two fragmented protons from the same H{sub {sup +}} ion decreasing their relative distance in the analysed cases. These forces align the interproton vector along the motion direction. They also tend the two-proton energy loss to the value of two isolated protons when at early times it is rather larger. Nevertheless most parts of these wake effects cannot be corroborated experimentally as they are masked by the projectile collisions with target nuclei in our numerical experiment. These collisions cancel the screening produced by the wake forces, increasing the interproton distance even faster than for bare Coulomb explosion. Also they misalign the interproton vector along the motion direction and contribute moderately to increase the energy loss of the fragmented H{sub {sup +}} ion. These nuclear collisions effects are more significant in reducing projectile velocity.

  20. The Zero-Degree Detector system for fragmentation studies

    International Nuclear Information System (INIS)

    Adams, J.H.; Christl, M.J.; Howell, L.W.; Kuznetsov, E.

    2007-01-01

    The measurement of nuclear fragmentation cross-sections requires the detection and identification of individual projectile fragments. If light and heavy fragments are recorded in the same detector, it may be impossible to distinguish the signal from the light fragment. To overcome this problem, we have developed the Zero-degree Detector System (ZDDS). The ZDDS enables the measurement of cross-sections for light fragment production by using pixelated detectors to separately measure the signals of each fragment. The system has been used to measure the fragmentation of beams as heavy as Fe at the NASA Space Radiation Laboratory at Brookhaven National Laboratory and the Heavy Ion Medical Accelerator in Chiba, Japan

  1. Introduction to fragment-based drug discovery.

    Science.gov (United States)

    Erlanson, Daniel A

    2012-01-01

    Fragment-based drug discovery (FBDD) has emerged in the past decade as a powerful tool for discovering drug leads. The approach first identifies starting points: very small molecules (fragments) that are about half the size of typical drugs. These fragments are then expanded or linked together to generate drug leads. Although the origins of the technique date back some 30 years, it was only in the mid-1990s that experimental techniques became sufficiently sensitive and rapid for the concept to be become practical. Since that time, the field has exploded: FBDD has played a role in discovery of at least 18 drugs that have entered the clinic, and practitioners of FBDD can be found throughout the world in both academia and industry. Literally dozens of reviews have been published on various aspects of FBDD or on the field as a whole, as have three books (Jahnke and Erlanson, Fragment-based approaches in drug discovery, 2006; Zartler and Shapiro, Fragment-based drug discovery: a practical approach, 2008; Kuo, Fragment based drug design: tools, practical approaches, and examples, 2011). However, this chapter will assume that the reader is approaching the field with little prior knowledge. It will introduce some of the key concepts, set the stage for the chapters to follow, and demonstrate how X-ray crystallography plays a central role in fragment identification and advancement.

  2. Mechanisms Affecting Population Density in Fragmented Habitat

    Directory of Open Access Journals (Sweden)

    Lutz Tischendorf

    2005-06-01

    Full Text Available We conducted a factorial simulation experiment to analyze the relative importance of movement pattern, boundary-crossing probability, and mortality in habitat and matrix on population density, and its dependency on habitat fragmentation, as well as inter-patch distance. We also examined how the initial response of a species to a fragmentation event may affect our observations of population density in post-fragmentation experiments. We found that the boundary-crossing probability from habitat to matrix, which partly determines the emigration rate, is the most important determinant for population density within habitat patches. The probability of crossing a boundary from matrix to habitat had a weaker, but positive, effect on population density. Movement behavior in habitat had a stronger effect on population density than movement behavior in matrix. Habitat fragmentation and inter-patch distance may have a positive or negative effect on population density. The direction of both effects depends on two factors. First, when the boundary-crossing probability from habitat to matrix is high, population density may decline with increasing habitat fragmentation. Conversely, for species with a high matrix-to-habitat boundary-crossing probability, population density may increase with increasing habitat fragmentation. Second, the initial distribution of individuals across the landscape: we found that habitat fragmentation and inter-patch distance were positively correlated with population density when individuals were distributed across matrix and habitat at the beginning of our simulation experiments. The direction of these relationships changed to negative when individuals were initially distributed across habitat only. Our findings imply that the speed of the initial response of organisms to habitat fragmentation events may determine the direction of observed relationships between habitat fragmentation and population density. The time scale of post-fragmentation

  3. Quark fragmentation in e+e- collisions

    International Nuclear Information System (INIS)

    Oddone, P.

    1984-12-01

    This brief review of new results in quark and gluon fragmentation observed in e + e - collisions concentrates mostly on PEP results and, within PEP, mostly on TPC results. The new PETRA results have been reported at this conference by M. Davier. It is restricted to results on light quark fragmentation since the results on heavy quark fragmentation have been reported by J. Chapman

  4. Fragmentation of a 500 MeV/nucleon 86Kr beam, investigated at the GSI projectile fragment separator

    International Nuclear Information System (INIS)

    Weber, M.; Donzaud, C.; Geissel, H.; Grewe, A.; Lewitowicz, M.; Magel, A.; Mueller, A.C.; Nickel, F.; Pfuetzner, M.; Piechaczek, A.; Pravikoff, M.; Roeckl, E.; Rykaczewski, K.; Saint-Laurent, M.G.; Schall, I.; Stephan, C.; Tassan-Got, L.; Voss, B.

    1993-10-01

    Production cross-sections and longitudinal momentum distributions have been investigated for reactions between a 500 MeV/nucleon 86 Kr beam and beryllium, copper and tantalum targets. Fragments in a wide A/Z range were studied at the projectile-fragment separator FRS at GSI. The experimental production cross-sections have been used for testing the predictions obtained from a semi-empirical parameterization, a statistical abrasion model and an intranuclear-cascade model. The present study allows to extrapolate the production cross-sections towards very neutron-rich isotopes such as the doubly magic nucleus 78 Ni. For fragments close to the projectile the measured longitudinal momentum distributions agrees qualitatively with a semi-empirical parameterization, which is based on the two-step picture of the fragmentation process. The momentum widths of lighter fragments, however, show deviations from this simple picture. (orig.)

  5. Ternary-fragmentation-driving potential energies of 252Cf

    Science.gov (United States)

    Karthikraj, C.; Ren, Zhongzhou

    2017-12-01

    Within the framework of a simple macroscopic model, the ternary-fragmentation-driving potential energies of 252Cf are studied. In this work, all possible ternary-fragment combinations of 252Cf are generated by the use of atomic mass evaluation-2016 (AME2016) data and these combinations are minimized by using a two-dimensional minimization approach. This minimization process can be done in two ways: (i) with respect to proton numbers (Z1, Z2, Z3) and (ii) with respect to neutron numbers (N1, N2, N3) of the ternary fragments. In this paper, the driving potential energies for the ternary breakup of 252Cf are presented for both the spherical and deformed as well as the proton-minimized and neutron-minimized ternary fragments. From the proton-minimized spherical ternary fragments, we have obtained different possible ternary configurations with a minimum driving potential, in particular, the experimental expectation of Sn + Ni + Ca ternary fragmentation. However, the neutron-minimized ternary fragments exhibit a driving potential minimum in the true-ternary-fission (TTF) region as well. Further, the Q -value energy systematics of the neutron-minimized ternary fragments show larger values for the TTF fragments. From this, we have concluded that the TTF region fragments with the least driving potential and high Q values have a strong possibility in the ternary fragmentation of 252Cf. Further, the role of ground-state deformations (β2, β3, β4, and β6) in the ternary breakup of 252Cf is also studied. The deformed ternary fragmentation, which involves Z3=12 -19 fragments, possesses the driving potential minimum due to the larger oblate deformations. We also found that the ground-state deformations, particularly β2, strongly influence the driving potential energies and play a major role in determining the most probable fragment combinations in the ternary breakup of 252Cf.

  6. Architectural fragments

    DEFF Research Database (Denmark)

    Bang, Jacob Sebastian

    2018-01-01

    I have created a large collection of plaster models: a collection of Obstructions, errors and opportunities that may develop into architecture. The models are fragments of different complex shapes as well as more simple circular models with different profiling and diameters. In this contect I have....... I try to invent the ways of drawing the models - that decode and unfold them into architectural fragments- into future buildings or constructions in the landscape. [1] Luigi Moretti: Italian architect, 1907 - 1973 [2] Man Ray: American artist, 1890 - 1976. in 2015, I saw the wonderful exhibition...... "Man Ray - Human Equations" at the Glyptotek in Copenhagen, organized by the Philips Collection in Washington D.C. and the Israel Museum in Jerusalem (in 2013). See also: "Man Ray - Human Equations" catalogue published by Hatje Cantz Verlag, Germany, 2014....

  7. Chemical Production using Fission Fragments

    International Nuclear Information System (INIS)

    Dawson, J. K.; Moseley, F.

    1960-01-01

    Some reactor design considerations of the use of fission recoil fragment energy for the production of chemicals of industrial importance have been discussed previously in a paper given at the Second United Nations International Conference on the Peaceful Uses of Atomic Energy [A/Conf. 15/P.76]. The present paper summarizes more recent progress made on this topic at AERE, Harwell. The range-energy relationship for fission fragments is discussed in the context of the choice of fuel system for a chemical production reactor, and the experimental observation of a variation of chemical effect along the length of a fission fragment track is described for the irradiation of nitrogen-oxygen mixtures. Recent results are given on the effect of fission fragments on carbon monoxide-hydrogen gas mixtures and on water vapour. No system investigated to date shows any outstanding promise for large-scale chemical production. (author) [fr

  8. The dynamics of fragment formation

    International Nuclear Information System (INIS)

    Keane, D.

    1994-09-01

    We demonstrate that in the Quantum Molecular Dynamics model, dynamical correlations can result in the production rate for final state nucleon clusters (and hence composite fragments) being higher than would be expected if statistics and the available phase space were dominant in determining composite formation. An intranuclear cascade or a Boltzmann-Uehling-Uhlenbeck model, combined with a statistical approach in the late stage of the collision to determine composites, provides an equivalent description only under limited conditions of centrality and beam energy. We use data on participant fragment production in Au + Au collisions in the Bevalac's BOS time projection chamber to map out the parameter space where statistical clustering provides a good description. In particular, we investigate momentum-space densities of fragments up to 4 He as a function of fragment transverse momentum, azimuth relative to the reaction plane, rapidity, multiplicity and beam energy

  9. Hands as markers of fragmentation

    Directory of Open Access Journals (Sweden)

    A. Barnard

    2005-07-01

    Full Text Available Margaret Atwood is an internationally read, translated, and critiqued writer whose novels have established her as one of the most esteemed authors in English (McCombs & Palmer, 1991:1. Critical studies of her work deal mainly with notions of identity from psychoanalytical perspectives. This study has identified a gap in current critical studies on Atwood’s works, namely the challenging of textual unity which is paralleled in the challenging of the traditional (single narrative voice. The challenging of textual unity and the single narrative voice brings about the fragmentation of both. This article will focus on the role that hands play as markers of fragmentation in “The Blind Assassin” (2000. In the novel, the writing hand destabilises the narrative voice, since it is not connected to the voice of a single author. If the author of the text – the final signified – is eliminated, the text becomes fragmentary and open, inviting the reader to contribute to the creation of meaning. Hands play a signficant role in foregrounding the narrator’s fragmented identity, and consequently, the fragmentation of the text. We will investigate this concept in the light of Roland Barthes’ notion of the scriptor, whose hand is metaphorically severed from his or her “voice”. Instead of the text being a unified entity, it becomes unstable and it displays the absence of hierarchical textual levels. Based mainly on Barthes’ writings, this article concludes that hands foreground the narrator’s fragmented identity, which is paralleled in the fragmented text.

  10. Nuclear Fragmentation Induced by Relativistic Projectiles Studied in the 4$\\pi$ Configuration of Plastic Track Detectors

    CERN Multimedia

    2002-01-01

    % EMU19 \\\\ \\\\ The collisions of heavy ions at relativistic energies have been studied to explore a number of questions related with hot and dense nuclear matter in order to extend our knowledge of nuclear equation-of-state. There are other aspects of these interactions which are studied to expound the process of projectile and/or target disintegrations. The disintegrations in question could be simply binary fissions or more complex processes leading to spallation or complete fragmentation. These important aspects of nuclear reactions are prone to investigations with nuclear track detectors. \\\\ \\\\One of the comparatively new track detector materials, CR-39, is sensitive enough to record particles of Z~$\\geq$~6 with almost 100\\% efficiency up to highly relativistic energies. The wide angle acceptance and exclusive measurements possible with plastic track detectors offer an opportunity to use them in a variety of situations in which high energy charged fragments are produced. The off-line nature of measuring tra...

  11. Heavy fragment radioactivity

    International Nuclear Information System (INIS)

    Silisteanu, I.

    1991-06-01

    The effect of collective mode excitation in heavy fragment radioactivity (HFR) is explored and discussed in the light of current experimental data. It is found that the coupling and resonance effects in fragment interaction and also the proper angular momentum effects may lead to an important enhancing of the emission process. New useful procedures are proposed for the study of nuclear decay properties. The relations between different decay processes are investigated in detail. We are also trying to understand and explain in a unified way the reaction mechanisms in decay phenomena. (author). 17 refs, 4 figs, 3 tabs

  12. An Algebra for Program Fragments

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun; Madsen, Ole Lehrmann; Møller-Pedersen, Birger

    1985-01-01

    Program fragments are described either by strings in the concrete syntax or by constructor applications in the abstract syntax. By defining conversions between these forms, both may be intermixed. Program fragments are constructed by terminal and nonterminal symbols from the grammar and by variab...

  13. Fragment Impact Toolkit (FIT)

    Energy Technology Data Exchange (ETDEWEB)

    Shevitz, Daniel Wolf [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Key, Brian P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Garcia, Daniel B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-05

    The Fragment Impact Toolkit (FIT) is a software package used for probabilistic consequence evaluation of fragmenting sources. The typical use case for FIT is to simulate an exploding shell and evaluate the consequence on nearby objects. FIT is written in the programming language Python and is designed as a collection of interacting software modules. Each module has a function that interacts with the other modules to produce desired results.

  14. A model for projectile fragmentation

    International Nuclear Information System (INIS)

    Chaudhuri, G; Mallik, S; Gupta, S Das

    2013-01-01

    A model for projectile fragmentation is developed whose origin can be traced back to the Bevalac era. The model positions itself between the phenomenological EPAX parametrization and transport models like 'Heavy Ion Phase Space Exploration' (HIPSE) model and antisymmetrised molecular dynamics (AMD) model. A very simple impact parameter dependence of input temperature is incorporated in the model which helps to analyze the more peripheral collisions. The model is applied to calculate the charge, isotopic distributions, average number of intermediate mass fragments and the average size of largest cluster at different Z bound of different projectile fragmentation reactions at different energies.

  15. Gamma Radiation from Fission Fragments

    International Nuclear Information System (INIS)

    Higbie, Jack

    1969-10-01

    The gamma radiation from the fragments of the thermal neutron fission of 235 U has been investigated, and the preliminary data are presented here with suggestions for further lines of research and some possible interpretations of the data. The data have direct bearing on the fission process and the mode of fragment de-excitation. The parameters measured are the radiation decay curve for the time interval (1 - 7) x 10 -10 sec after fission, the photon yield, the total gamma ray energy yield, and the average photon energy. The last three quantities are measured as a function of the fragment mass

  16. Gamma Radiation from Fission Fragments

    Energy Technology Data Exchange (ETDEWEB)

    Higbie, Jack

    1969-10-15

    The gamma radiation from the fragments of the thermal neutron fission of {sup 235}U has been investigated, and the preliminary data are presented here with suggestions for further lines of research and some possible interpretations of the data. The data have direct bearing on the fission process and the mode of fragment de-excitation. The parameters measured are the radiation decay curve for the time interval (1 - 7) x 10{sup -10} sec after fission, the photon yield, the total gamma ray energy yield, and the average photon energy. The last three quantities are measured as a function of the fragment mass.

  17. Anisotropy in highly charged ion induced molecule fragmentation

    International Nuclear Information System (INIS)

    Juhasz, Z.; Sulik, B.; Fremont, F.; Chesnel, J.Y.; Hajaji, A.

    2006-01-01

    Complete text of publication follows. Studying fragmentation processes of biologically relevant molecules due to highly charged ion impact is important to understand radiation damage in biological tissues. Energy spectra of the charged molecule fragments may reveal the different fragmentation patterns meanwhile the angular distributions of the fragments characterize the dependence of fragmentation probability on the initial orientation of the molecule. The research to explore the angular distribution of the molecule fragments has only recently been started[1]. In 2006 we performed measurements at ARIBE facility at GANIL, Caen (France), in order to investigate orientation effects in molecule fragmentation. Fragmentation of H 2 O, C 6 H 6 and CH 4 , which represent different level of symmetry, have been studied by 60 keV N 6+ ion impact. Energy spectra of the charged fragments at different observation angles have been taken. As our example spectra show the different protonic peaks can be attributed to different fragmentation processes. Significant anisotropy can be seen in the different processes. The strongest evidence for the anisotropy can be seen in the spectra of C 6 H 6 , where the spectra appear isotropic in almost the whole observed energy range except one peak, which has a strong angular dependence and is maximal around 90 deg. (author)

  18. Absolute fragmentation cross sections in atom-molecule collisions: Scaling laws for non-statistical fragmentation of polycyclic aromatic hydrocarbon molecules

    Energy Technology Data Exchange (ETDEWEB)

    Chen, T.; Gatchell, M.; Stockett, M. H.; Alexander, J. D.; Schmidt, H. T.; Cederquist, H.; Zettergren, H., E-mail: henning@fysik.su.se [Department of Physics, Stockholm University, S-106 91 Stockholm (Sweden); Zhang, Y. [Department of Mathematics, Faculty of Physics, M. V. Lomonosov Moscow State University, Leninskie Gory, 119991 Moscow (Russian Federation); Rousseau, P.; Maclot, S.; Delaunay, R.; Adoui, L. [CIMAP, UMR 6252, CEA/CNRS/ENSICAEN/Université de Caen Basse-Normandie, bd Henri Becquerel, BP 5133, F-14070 Caen Cedex 05 (France); Université de Caen Basse-Normandie, Esplanade de la Paix, F-14032 Caen (France); Domaracka, A.; Huber, B. A. [CIMAP, UMR 6252, CEA/CNRS/ENSICAEN/Université de Caen Basse-Normandie, bd Henri Becquerel, BP 5133, F-14070 Caen Cedex 05 (France); Schlathölter, T. [Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747AG Groningen (Netherlands)

    2014-06-14

    We present scaling laws for absolute cross sections for non-statistical fragmentation in collisions between Polycyclic Aromatic Hydrocarbons (PAH/PAH{sup +}) and hydrogen or helium atoms with kinetic energies ranging from 50 eV to 10 keV. Further, we calculate the total fragmentation cross sections (including statistical fragmentation) for 110 eV PAH/PAH{sup +} + He collisions, and show that they compare well with experimental results. We demonstrate that non-statistical fragmentation becomes dominant for large PAHs and that it yields highly reactive fragments forming strong covalent bonds with atoms (H and N) and molecules (C{sub 6}H{sub 5}). Thus nonstatistical fragmentation may be an effective initial step in the formation of, e.g., Polycyclic Aromatic Nitrogen Heterocycles (PANHs). This relates to recent discussions on the evolution of PAHNs in space and the reactivities of defect graphene structures.

  19. Remarks about the hypothesis of limiting fragmentation

    International Nuclear Information System (INIS)

    Chou, T.T.; Yang, C.N.

    1987-01-01

    Remarks are made about the hypothesis of limiting fragmentation. In particular, the concept of favored and disfavored fragment distribution is introduced. Also, a sum rule is proved leading to a useful quantity called energy-fragmentation fraction. (author). 11 refs, 1 fig., 2 tabs

  20. Polarization and alignment of nucleus fission fragments

    International Nuclear Information System (INIS)

    Barabanov, A.L.; Grechukhin, D.P.

    1987-01-01

    Correlation of fragment orientation with orientation axis of fissile nucleus and with n-vector f vector of fragment divergence is considered. Estimations of polarization and alignment of fission fragments of preliminarily oriented nuclei in correlation (with n-vector f recording) and integral (with n-vector f averaging) experiments were conducted. It is shown that high sensitivity of polarization and fragment alignment to the character of nucleus movement at the stage of descent from barrier to rupture point exists

  1. Nuclear energy release from fragmentation

    Energy Technology Data Exchange (ETDEWEB)

    Li, Cheng [The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Souza, S.R. [Instituto de Física, Universidade Federal do Rio de Janeiro Cidade Universitária, Caixa Postal 68528, 21945-970 Rio de Janeiro (Brazil); Tsang, M.B. [The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); National Superconducting Cyclotron Laboratory and Physics and Astronomy Department, Michigan State University, East Lansing, MI 48824 (United States); Zhang, Feng-Shou, E-mail: fszhang@bnu.edu.cn [The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Center of Theoretical Nuclear Physics, National Laboratory of Heavy Ion Accelerator of Lanzhou, Lanzhou 730000 (China)

    2016-08-15

    It is well known that binary fission occurs with positive energy gain. In this article we examine the energetics of splitting uranium and thorium isotopes into various numbers of fragments (from two to eight) with nearly equal size. We find that the energy released by splitting {sup 230,232}Th and {sup 235,238}U into three equal size fragments is largest. The statistical multifragmentation model (SMM) is applied to calculate the probability of different breakup channels for excited nuclei. By weighing the probability distributions of fragment multiplicity at different excitation energies, we find the peaks of energy release for {sup 230,232}Th and {sup 235,238}U are around 0.7–0.75 MeV/u at excitation energy between 1.2 and 2 MeV/u in the primary breakup process. Taking into account the secondary de-excitation processes of primary fragments with the GEMINI code, these energy peaks fall to about 0.45 MeV/u.

  2. Dihadron fragmentation function and its evolution

    International Nuclear Information System (INIS)

    Majumder, A.; Wang Xinnian

    2004-01-01

    Dihadron fragmentation functions and their evolution are studied in the process of e + e - annihilation. Under the collinear factorization approximation and facilitated by the cut-vertex technique, the two hadron inclusive cross section at leading order is shown to factorize into a short distance parton cross section and a long distance dihadron fragmentation function. We provide the definition of such a dihadron fragmentation function in terms of parton matrix elements and derive its Dokshitzer-Gribov-Lipatov-Altarelli-Parisi evolution equation at leading log. The evolution equation for the nonsinglet quark fragmentation function is solved numerically with a simple ansatz for the initial condition and results are presented for cases of physical interest

  3. SCEDS: protein fragments for molecular replacement in Phaser

    Energy Technology Data Exchange (ETDEWEB)

    McCoy, Airlie J., E-mail: ajm201@cam.ac.uk [University of Cambridge, Hills Road, Cambridge CB2 0XY (United Kingdom); Nicholls, Robert A. [MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH (United Kingdom); Schneider, Thomas R. [Hamburg Unit c/o DESY, Notkestrasse 85, 22603 Hamburg (Germany); University of Cambridge, Hills Road, Cambridge CB2 0XY (United Kingdom)

    2013-11-01

    Protein fragments suitable for use in molecular replacement can be generated by normal-mode perturbation, analysis of the difference distance matrix of the original versus normal-mode perturbed structures, and SCEDS, a score that measures the sphericity, continuity, equality and density of the resulting fragments. A method is described for generating protein fragments suitable for use as molecular-replacement (MR) template models. The template model for a protein suspected to undergo a conformational change is perturbed along combinations of low-frequency normal modes of the elastic network model. The unperturbed structure is then compared with each perturbed structure in turn and the structurally invariant regions are identified by analysing the difference distance matrix. These fragments are scored with SCEDS, which is a combined measure of the sphericity of the fragments, the continuity of the fragments with respect to the polypeptide chain, the equality in number of atoms in the fragments and the density of C{sup α} atoms in the triaxial ellipsoid of the fragment extents. The fragment divisions with the highest SCEDS are then used as separate template models for MR. Test cases show that where the protein contains fragments that undergo a change in juxtaposition between template model and target, SCEDS can identify fragments that lead to a lower R factor after ten cycles of all-atom refinement with REFMAC5 than the original template structure. The method has been implemented in the software Phaser.

  4. SCEDS: protein fragments for molecular replacement in Phaser

    International Nuclear Information System (INIS)

    McCoy, Airlie J.; Nicholls, Robert A.; Schneider, Thomas R.

    2013-01-01

    Protein fragments suitable for use in molecular replacement can be generated by normal-mode perturbation, analysis of the difference distance matrix of the original versus normal-mode perturbed structures, and SCEDS, a score that measures the sphericity, continuity, equality and density of the resulting fragments. A method is described for generating protein fragments suitable for use as molecular-replacement (MR) template models. The template model for a protein suspected to undergo a conformational change is perturbed along combinations of low-frequency normal modes of the elastic network model. The unperturbed structure is then compared with each perturbed structure in turn and the structurally invariant regions are identified by analysing the difference distance matrix. These fragments are scored with SCEDS, which is a combined measure of the sphericity of the fragments, the continuity of the fragments with respect to the polypeptide chain, the equality in number of atoms in the fragments and the density of C α atoms in the triaxial ellipsoid of the fragment extents. The fragment divisions with the highest SCEDS are then used as separate template models for MR. Test cases show that where the protein contains fragments that undergo a change in juxtaposition between template model and target, SCEDS can identify fragments that lead to a lower R factor after ten cycles of all-atom refinement with REFMAC5 than the original template structure. The method has been implemented in the software Phaser

  5. Evolution equations for extended dihadron fragmentation functions

    International Nuclear Information System (INIS)

    Ceccopieri, F.A.; Bacchetta, A.

    2007-03-01

    We consider dihadron fragmentation functions, describing the fragmentation of a parton in two unpolarized hadrons, and in particular extended dihadron fragmentation functions, explicitly dependent on the invariant mass, M h , of the hadron pair. We first rederive the known results on M h -integrated functions using Jet Calculus techniques, and then we present the evolution equations for extended dihadron fragmentation functions. Our results are relevant for the analysis of experimental measurements of two-particle-inclusive processes at different energies. (orig.)

  6. Quantitative experimental modelling of fragmentation during explosive volcanism

    Science.gov (United States)

    Thordén Haug, Ø.; Galland, O.; Gisler, G.

    2012-04-01

    Phreatomagmatic eruptions results from the violent interaction between magma and an external source of water, such as ground water or a lake. This interaction causes fragmentation of the magma and/or the host rock, resulting in coarse-grained (lapilli) to very fine-grained (ash) material. The products of phreatomagmatic explosions are classically described by their fragment size distribution, which commonly follows power laws of exponent D. Such descriptive approach, however, considers the final products only and do not provide information on the dynamics of fragmentation. The aim of this contribution is thus to address the following fundamental questions. What are the physics that govern fragmentation processes? How fragmentation occurs through time? What are the mechanisms that produce power law fragment size distributions? And what are the scaling laws that control the exponent D? To address these questions, we performed a quantitative experimental study. The setup consists of a Hele-Shaw cell filled with a layer of cohesive silica flour, at the base of which a pulse of pressurized air is injected, leading to fragmentation of the layer of flour. The fragmentation process is monitored through time using a high-speed camera. By varying systematically the air pressure (P) and the thickness of the flour layer (h) we observed two morphologies of fragmentation: "lift off" where the silica flour above the injection inlet is ejected upwards, and "channeling" where the air pierces through the layer along sub-vertical conduit. By building a phase diagram, we show that the morphology is controlled by P/dgh, where d is the density of the flour and g is the gravitational acceleration. To quantify the fragmentation process, we developed a Matlab image analysis program, which calculates the number and sizes of the fragments, and so the fragment size distribution, during the experiments. The fragment size distributions are in general described by power law distributions of

  7. Impact failure and fragmentation properties of metals

    Energy Technology Data Exchange (ETDEWEB)

    Grady, D.E. [Applied Research Associates, Albuquerque, NM (United States); Kipp, M.E. [Sandia National Labs., Albuquerque, NM (United States)

    1998-03-01

    In the present study we describe the development of an experimental fracture material property test method specific to dynamic fragmentation. Spherical test samples of the metals of interest are subjected to controlled impulsive stress loads by acceleration to high velocities with a light-gas launcher facility and subsequent normal impact on thin plates. Motion, deformation and fragmentation of the test samples are diagnosed with multiple flash radiography methods. The impact plate materials are selected to be transparent to the x-ray method so that only test metal material is imaged. Through a systematic series of such tests both strain-to-failure and fragmentation resistance properties are determined through this experimental method. Fragmentation property data for several steels, copper, aluminum, tantalum and titanium have been obtained to date. Aspects of the dynamic data have been analyzed with computational methods to achieve a better understanding of the processes leading to failure and fragmentation, and to test an existing computational fragmentation model.

  8. Predicting "Hot" and "Warm" Spots for Fragment Binding.

    Science.gov (United States)

    Rathi, Prakash Chandra; Ludlow, R Frederick; Hall, Richard J; Murray, Christopher W; Mortenson, Paul N; Verdonk, Marcel L

    2017-05-11

    Computational fragment mapping methods aim to predict hotspots on protein surfaces where small fragments will bind. Such methods are popular for druggability assessment as well as structure-based design. However, to date researchers developing or using such tools have had no clear way of assessing the performance of these methods. Here, we introduce the first diverse, high quality validation set for computational fragment mapping. The set contains 52 diverse examples of fragment binding "hot" and "warm" spots from the Protein Data Bank (PDB). Additionally, we describe PLImap, a novel protocol for fragment mapping based on the Protein-Ligand Informatics force field (PLIff). We evaluate PLImap against the new fragment mapping test set, and compare its performance to that of simple shape-based algorithms and fragment docking using GOLD. PLImap is made publicly available from https://bitbucket.org/AstexUK/pli .

  9. Scaling and critical behaviour in nuclear fragmentation

    International Nuclear Information System (INIS)

    Campi, X.

    1990-09-01

    These notes review recent results on nuclear fragmentation. An analysis of experimental data from exclusive experiments is made in the framework of modern theories of fragmentation of finite size objects. We discuss the existence of a critical regime of fragmentation and the relevance of scaling and finite size scaling

  10. Actors or Spectators? Vulnerability and Critical Environmental Law

    Directory of Open Access Journals (Sweden)

    Andreas Philippopoulos‐Mihalopoulos

    2013-12-01

    Full Text Available The question of whether we as humans should remain spectators of the great theatre of ecological disaster or become actors is a false dichotomy. In this chapter, I argue that both are needed, since the critical distance of spectatorship does not annul the need for immersion in the ecological continuum. A tool in the realisation of this is the concept of vulnerability, which is here conceptualised as a space of ‘the middle’ (as opposed, emphatically, to ‘the centre’ and offers an opportunity to think away from the sterile debate on eco/anthropocentricity and from such limiting hierarchies as animal/human, human/environmental, natural/artificial. This new, vulnerable position of the middle allows the reconfiguration of ecological processes, and more specifically, the position of environmental law in relation to them. Environmental law now finds itself amidst a new, moving, ‘open ecology’ of social, biological and ecological processes. This is a new, radical conceptualisation of what I have called ‘critical environmental law’, based upon an epistemology of observation and an ontology of being part of this open ecology. Environmental law, in this light, is simultaneously reformulated as being an invitation to disciplinary and ontological openness and yet a call to remain immanent within existing legal structures. This finds expression in four critical environmental positions that set the stage for the further elaboration of a critical environmental law. La cuestión de si nosotros, como seres humanos, debemos seguir siendo espectadores del gran teatro de la catástrofe ecológica o convertirnos en actores es una dicotomía falsa. En este artículo se sostiene que ambos son necesarios, ya que la distancia crítica del espectador no anula la necesidad de una inmersión en el continuum ecológico. Una herramienta para la realización de esto es el concepto de vulnerabilidad, que aquí se concibe como un espacio 'intermedio' (en oposici

  11. The politics of municipal fragmentation in Ghana

    Directory of Open Access Journals (Sweden)

    Abdulai Kuyini Mohammed

    2015-06-01

    Full Text Available The scholarly debate over the rival merits of local government consolidation and fragmentation is an old but enduring one. However, in this debate very little attention has been focused on the political dimension of council amalgamation and fragmentation – yet political considerations play a central role in both the formulation and outcomes of de-concentration policy. The purpose of this article is to fill a gap in the literature by examining local government fragmentation in Ghana from 1988 to 2014. The article does this by identifying the key players and analysing their interests and gains, as well as the tensions arising from the fragmentation exercise. The implications from the Ghanaian case for more general theories of fragmentation are drawn out.

  12. Jet evolution in hot and cold QCD matter

    Energy Technology Data Exchange (ETDEWEB)

    Domdey, Svend Oliver

    2010-07-23

    In this thesis, we study the evolution of energetic partons in hot and cold QCD matter. In both cases, interactions with the medium lead to energy loss of the parton and its transverse momentum broadens. The propagation of partons in cold nuclear matter can be investigated experimentally in deep-inelastic scattering (DIS) on nuclei. We use the dipole model to calculate transverse momentum broadening in DIS on nuclei and compare to experimental data from HERMES. In hot matter, the evolution of the parton shower is strongly modified. To calculate this modification, we construct an additional scattering term in the QCD evolution equations which accounts for scattering of partons in the quark-gluon plasma. With this scattering term, we compute the modified gluon distribution in the shower at small momentum fractions. Furthermore, we calculate the modified fragmentation function of gluons into pions. The scattering term causes energy loss of the parton shower which leads to a suppression of hadrons with large transverse momentum. In the third part of this thesis, we study double dijet production in hadron collisions. This process contains information about the transverse parton distribution of hadrons. As main result, we find that double dijet production will allow for a study of the transverse growth of hadronic wave functions at the LHC. (orig.)

  13. Heart Rate Fragmentation: A Symbolic Dynamical Approach

    Directory of Open Access Journals (Sweden)

    Madalena D. Costa

    2017-11-01

    Full Text Available Background: We recently introduced the concept of heart rate fragmentation along with a set of metrics for its quantification. The term was coined to refer to an increase in the percentage of changes in heart rate acceleration sign, a dynamical marker of a type of anomalous variability. The effort was motivated by the observation that fragmentation, which is consistent with the breakdown of the neuroautonomic-electrophysiologic control system of the sino-atrial node, could confound traditional short-term analysis of heart rate variability.Objective: The objectives of this study were to: (1 introduce a symbolic dynamical approach to the problem of quantifying heart rate fragmentation; (2 evaluate how the distribution of the different dynamical patterns (“words” varied with the participants' age in a group of healthy subjects and patients with coronary artery disease (CAD; and (3 quantify the differences in the fragmentation patterns between the two sample populations.Methods: The symbolic dynamical method employed here was based on a ternary map of the increment NN interval time series and on the analysis of the relative frequency of symbolic sequences (words with a pre-defined set of features. We analyzed annotated, open-access Holter databases of healthy subjects and patients with CAD, provided by the University of Rochester Telemetric and Holter ECG Warehouse (THEW.Results: The degree of fragmentation was significantly higher in older individuals than in their younger counterparts. However, the fragmentation patterns were different in the two sample populations. In healthy subjects, older age was significantly associated with a higher percentage of transitions from acceleration/deceleration to zero acceleration and vice versa (termed “soft” inflection points. In patients with CAD, older age was also significantly associated with higher percentages of frank reversals in heart rate acceleration (transitions from acceleration to

  14. Baculovirus display of functional antibody Fab fragments.

    Science.gov (United States)

    Takada, Shinya; Ogawa, Takafumi; Matsui, Kazusa; Suzuki, Tasuku; Katsuda, Tomohisa; Yamaji, Hideki

    2015-08-01

    The generation of a recombinant baculovirus that displays antibody Fab fragments on the surface was investigated. A recombinant baculovirus was engineered so that the heavy chain (Hc; Fd fragment) of a mouse Fab fragment was expressed as a fusion to the N-terminus of baculovirus gp64, while the light chain of the Fab fragment was simultaneously expressed as a secretory protein. Following infection of Sf9 insect cells with the recombinant baculovirus, the culture supernatant was analyzed by enzyme-linked immunosorbent assay using antigen-coated microplates and either an anti-mouse IgG or an anti-gp64 antibody. A relatively strong signal was obtained in each case, showing antigen-binding activity in the culture supernatant. In western blot analysis of the culture supernatant using the anti-gp64 antibody, specific protein bands were detected at an electrophoretic mobility that coincided with the molecular weight of the Hc-gp64 fusion protein as well as that of gp64. Flow cytometry using a fluorescein isothiocyanate-conjugated antibody specific to mouse IgG successfully detected the Fab fragments on the surface of the Sf9 cells. These results suggest that immunologically functional antibody Fab fragments can be displayed on the surface of baculovirus particles, and that a fluorescence-activated cell sorter with a fluorescence-labeled antigen can isolate baculoviruses displaying specific Fab fragments. This successful baculovirus display of antibody Fab fragments may offer a novel approach for the efficient selection of specific antibodies.

  15. Molten aluminum alloy fuel fragmentation experiments

    International Nuclear Information System (INIS)

    Gabor, J.D.; Purviance, R.T.; Cassulo, J.C.; Spencer, B.W.

    1992-01-01

    Experiments were conducted in which molten aluminum alloys were injected into a 1.2 m deep pool of water. The parameters varied were (i) injectant material (8001 aluminum alloy and 12.3 wt% U-87.7 wt% Al), (ii) melt superheat (O to 50 K), (iii) water temperature (313, 343 and 373 K) and (iv) size and geometry of the pour stream (5, 10 and 20 mm diameter circular and 57 mm annular). The pour stream fragmentation was dominated by surface tension with large particles (∼30 mm) being formed from varicose wave breakup of the 10-mm circular pours and from the annular flow off a 57 mm diameter tube. The fragments produced by the 5 mm circular et were smaller (∼ mm), and the 20 mm jet which underwent sinuous wave breakup produced ∼100 mm fragments. The fragments froze to form solid particles in 313 K water, and when the water was ≥343 K, the melt fragments did not freeze during their transit through 1.2 m of water

  16. Simulations of High Speed Fragment Trajectories

    Science.gov (United States)

    Yeh, Peter; Attaway, Stephen; Arunajatesan, Srinivasan; Fisher, Travis

    2017-11-01

    Flying shrapnel from an explosion are capable of traveling at supersonic speeds and distances much farther than expected due to aerodynamic interactions. Predicting the trajectories and stable tumbling modes of arbitrary shaped fragments is a fundamental problem applicable to range safety calculations, damage assessment, and military technology. Traditional approaches rely on characterizing fragment flight using a single drag coefficient, which may be inaccurate for fragments with large aspect ratios. In our work we develop a procedure to simulate trajectories of arbitrary shaped fragments with higher fidelity using high performance computing. We employ a two-step approach in which the force and moment coefficients are first computed as a function of orientation using compressible computational fluid dynamics. The force and moment data are then input into a six-degree-of-freedom rigid body dynamics solver to integrate trajectories in time. Results of these high fidelity simulations allow us to further understand the flight dynamics and tumbling modes of a single fragment. Furthermore, we use these results to determine the validity and uncertainty of inexpensive methods such as the single drag coefficient model.

  17. Microstructural characterization of pipe bomb fragments

    International Nuclear Information System (INIS)

    Gregory, Otto; Oxley, Jimmie; Smith, James; Platek, Michael; Ghonem, Hamouda; Bernier, Evan; Downey, Markus; Cumminskey, Christopher

    2010-01-01

    Recovered pipe bomb fragments, exploded under controlled conditions, have been characterized using scanning electron microscopy, optical microscopy and microhardness. Specifically, this paper examines the microstructural changes in plain carbon-steel fragments collected after the controlled explosion of galvanized, schedule 40, continuously welded, steel pipes filled with various smokeless powders. A number of microstructural changes were observed in the recovered pipe fragments: deformation of the soft alpha-ferrite grains, deformation of pearlite colonies, twin formation, bands of distorted pearlite colonies, slip bands, and cross-slip bands. These microstructural changes were correlated with the relative energy of the smokeless powder fillers. The energy of the smokeless powder was reflected in a reduction in thickness of the pipe fragments (due to plastic strain prior to fracture) and an increase in microhardness. Moreover, within fragments from a single pipe, there was a radial variation in microhardness, with the microhardness at the outer wall being greater than that at the inner wall. These findings were consistent with the premise that, with the high energy fillers, extensive plastic deformation and wall thinning occurred prior to pipe fracture. Ultimately, the information collected from this investigation will be used to develop a database, where the fragment microstructure and microhardness will be correlated with type of explosive filler and bomb design. Some analyses, specifically wall thinning and microhardness, may aid in field characterization of explosive devices.

  18. Cryobiology of coral fragments.

    Science.gov (United States)

    Hagedorn, Mary; Farrell, Ann; Carter, Virginia L

    2013-02-01

    Around the world, coral reefs are dying due to human influences, and saving habitat alone may not stop this destruction. This investigation focused on the biological processes that will provide the first steps in understanding the cryobiology of whole coral fragments. Coral fragments are a partnership of coral tissue and endosymbiotic algae, Symbiodinium sp., commonly called zooxanthellae. These data reflected their separate sensitivities to chilling and a cryoprotectant (dimethyl sulfoxide) for the coral Pocillopora damicornis, as measured by tissue loss and Pulse Amplitude Modulated fluorometry 3weeks post-treatment. Five cryoprotectant treatments maintained the viability of the coral tissue and zooxanthellae at control values (1M dimethyl sulfoxide at 1.0, 1.5 and 2.0h exposures, and 1.5M dimethyl sulfoxide at 1.0 and 1.5h exposures, P>0.05, ANOVA), whereas 2M concentrations did not (Pzooxanthellae. During the winter when the fragments were chilled, the coral tissue remained relatively intact (∼25% loss) post-treatment, but the zooxanthellae numbers in the tissue declined after 5min of chilling (Pzooxanthellae numbers declined in response to chilling alone (P0.05, ANOVA), but it did not protect against the loss of zooxanthellae (Pzooxanthellae are the most sensitive element in the coral fragment complex and future cryopreservation protocols must be guided by their greater sensitivity. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. MaRaCluster: A Fragment Rarity Metric for Clustering Fragment Spectra in Shotgun Proteomics.

    Science.gov (United States)

    The, Matthew; Käll, Lukas

    2016-03-04

    Shotgun proteomics experiments generate large amounts of fragment spectra as primary data, normally with high redundancy between and within experiments. Here, we have devised a clustering technique to identify fragment spectra stemming from the same species of peptide. This is a powerful alternative method to traditional search engines for analyzing spectra, specifically useful for larger scale mass spectrometry studies. As an aid in this process, we propose a distance calculation relying on the rarity of experimental fragment peaks, following the intuition that peaks shared by only a few spectra offer more evidence than peaks shared by a large number of spectra. We used this distance calculation and a complete-linkage scheme to cluster data from a recent large-scale mass spectrometry-based study. The clusterings produced by our method have up to 40% more identified peptides for their consensus spectra compared to those produced by the previous state-of-the-art method. We see that our method would advance the construction of spectral libraries as well as serve as a tool for mining large sets of fragment spectra. The source code and Ubuntu binary packages are available at https://github.com/statisticalbiotechnology/maracluster (under an Apache 2.0 license).

  20. Fragment approaches in structure-based drug discovery

    International Nuclear Information System (INIS)

    Hubbard, Roderick E.

    2008-01-01

    Fragment-based methods are successfully generating novel and selective drug-like inhibitors of protein targets, with a number of groups reporting compounds entering clinical trials. This paper summarizes the key features of the approach as one of the tools in structure-guided drug discovery. There has been considerable interest recently in what is known as 'fragment-based lead discovery'. The novel feature of the approach is to begin with small low-affinity compounds. The main advantage is that a larger potential chemical diversity can be sampled with fewer compounds, which is particularly important for new target classes. The approach relies on careful design of the fragment library, a method that can detect binding of the fragment to the protein target, determination of the structure of the fragment bound to the target, and the conventional use of structural information to guide compound optimization. In this article the methods are reviewed, and experiences in fragment-based discovery of lead series of compounds against kinases such as PDK1 and ATPases such as Hsp90 are discussed. The examples illustrate some of the key benefits and issues of the approach and also provide anecdotal examples of the patterns seen in selectivity and the binding mode of fragments across different protein targets

  1. Fragmentation properties of 6Li

    International Nuclear Information System (INIS)

    Lovas, R.G.; Kruppa, A.T.; Beck, R.; Dickmann, F.

    1987-01-01

    The α+d and t+τ cluster structure of 6 Li is described in a microscopic α+d cluster model through quantities that enter into the description of cluster fragmentation processes. The states of the separate clusters α, d, t and τ are described as superpositions of Os Slater determinants belonging to different potential size parameters. To describe both the 6 Li and fragment state realistically, nucleon-nucleon forces optimized for the used model state spaces were constructed. The fragmentation properties predicted by them slightly differ from those calculated with some forces of common use provided the latter are modified so as to reproduce the α, d and 6 Li energies. (author) 61 refs.; 9 figs

  2. Geometrical scaling of jet fragmentation photons

    Energy Technology Data Exchange (ETDEWEB)

    Hattori, Koichi, E-mail: koichi.hattori@riken.jp [RIKEN BNL Research Center, Brookhaven National Laboratory, Upton NY 11973 (United States); Theoretical Research Division, Nishina Center, RIKEN, Wako, Saitama 351-0198 (Japan); McLerran, Larry, E-mail: mclerran@bnl.gov [RIKEN BNL Research Center, Brookhaven National Laboratory, Upton NY 11973 (United States); Physics Dept., Bdg. 510A, Brookhaven National Laboratory, Upton, NY-11973 (United States); Physics Dept., China Central Normal University, Wuhan (China); Schenke, Björn, E-mail: bschenke@bnl.gov [Physics Dept., Bdg. 510A, Brookhaven National Laboratory, Upton, NY-11973 (United States)

    2016-12-15

    We discuss jet fragmentation photons in ultrarelativistic heavy-ion collisions. We argue that, if the jet distribution satisfies geometrical scaling and an anisotropic spectrum, these properties are transferred to photons during the jet fragmentation.

  3. Bespoke Fragments

    DEFF Research Database (Denmark)

    Kruse Aagaard, Anders

    2017-01-01

    The PhD project Bespoke Fragments is investigating the space emerging in the exploration of the relationship between digital drawing and fabrication, and the field of materials and their properties and capacities. Through a series of different experiments, the project situates itself in a shuttli...

  4. Universal Jurisdiction between Unity and Fragmentation of International Criminal Law

    Directory of Open Access Journals (Sweden)

    Pasculli Maria Antonella

    2011-04-01

    Full Text Available This paper represents the outcome of research fellowship Marie Curie at the Universiteit Leiden -Campud Den Haag Grotius, Centre for International Legal Studies (prof. C. Stahn and prof. Larissa van den Herik, supervisors on the topic "The Fragmentation and the Diversification of International Criminal Law in a Global Society”.In my paper I will examine the question of whether Universal Jurisdiction (UJ leads to unity or fragmentation within International Criminal Law (ICL. Given that there is already quite a lot of literature on UJ, it is important to focus the research on the issue of fragmentation and/or unity rather than to deal with the issue of UJ more generally. I will focus on this topic in sections 1 and 2, explaining some cursory remarks to these issues in my analysis on fragmentation. In the introduction, I will briefly introduce UJ as a controversial form of jurisdiction, but still necessary given that territorial jurisdiction does not always function well in the case of international crime. I will demonstrate that many state parties to the International Criminal Court (ICC Statute have vested or reconfirmed UJ for the core crimes when implementing the ICC Statute. The leading question of my research is whether this practice has led or has the potential to lead to unity or rather to fragmentation within ICL. In the research I will approach this question from different perspectives.In section 1 I will examine how State parties have may actually enacted universal jurisdiction for the core crimes, with a view to determining whether there is indeed some unity on this front or whether the practice on this matter is actually rather diverse (or fragmented. Subsequently, I will analyse which conditions States have formulated for the exercise of UJ, and whether this practice is consistent (unity or again rather diverse (fragmentation. It might also be interesting to see whether States have different conditions for UJ over core crimes than

  5. Fracture mechanics model of fragmentation

    International Nuclear Information System (INIS)

    Glenn, L.A.; Gommerstadt, B.Y.; Chudnovsky, A.

    1986-01-01

    A model of the fragmentation process is developed, based on the theory of linear elastic fracture mechanics, which predicts the average fragment size as a function of strain rate and material properties. This approach permits a unification of previous results, yielding Griffith's solution in the low-strain-rate limit and Grady's solution at high strain rates

  6. Polymer fragmentation in extensional flow

    Energy Technology Data Exchange (ETDEWEB)

    Maroja, Armando M.; Oliveira, Fernando A.; Ciesla, Michal; Longa, Lech

    2001-06-01

    In this paper we present an analysis of fragmentation of dilute polymer solutions in extensional flow. The transition rate is investigated both from theoretical and computational approaches, where the existence of a Gaussian distribution for the breaking bonds has been controversial. We give as well an explanation for the low fragmentation frequency found in DNA experiments.

  7. Heavy-Quark Production in the Target Fragmentation Region

    CERN Document Server

    Graudenz, Dirk

    1997-01-01

    Fixed-target experiments permit the study of hadron production in the target fragmentation region. It is expected that the tagging of specific particles in the target fragments can be employed to introduce a bias in the hard scattering process towards a specific flavour content. The case of hadrons containing a heavy quark is particularly attractive because of the clear experimental signatures and the applicability of perturbative QCD. The standard approach to one-particle inclusive processes based on fragmentation functions is valid in the current fragmentation region and for large transverse momenta $p_T$ in the target fragmentation region, but it fails for particle production at small $p_T$ in the target fragmentation region. A collinear singularity, which cannot be absorbed in the standard way into the phenomenological distribution functions, prohibits the application of this procedure. This situation is remedied by the introduction of a new set of distribution functions, the target fragmentation function...

  8. Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin : Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry

    NARCIS (Netherlands)

    Mondal, Milon; Radeva, Nedyalka; Fanlo-Virgos, Hugo; Otto, Sijbren; Klebe, Gerhard; Hirsch, Anna K. H.

    2016-01-01

    Fragment-based drug design (FBDD) affords active compounds for biological targets. While there are numerous reports on FBDD by fragment growing/optimization, fragment linking has rarely been reported. Dynamic combinatorial chemistry (DCC) has become a powerful hit-identification strategy for

  9. Experimental modelling of fragmentation applied to volcanic explosions

    Science.gov (United States)

    Haug, Øystein Thordén; Galland, Olivier; Gisler, Galen R.

    2013-12-01

    Explosions during volcanic eruptions cause fragmentation of magma and host rock, resulting in fragments with sizes ranging from boulders to fine ash. The products can be described by fragment size distributions (FSD), which commonly follow power laws with exponent D. The processes that lead to power-law distributions and the physical parameters that control D remain unknown. We developed a quantitative experimental procedure to study the physics of the fragmentation process through time. The apparatus consists of a Hele-Shaw cell containing a layer of cohesive silica flour that is fragmented by a rapid injection of pressurized air. The evolving fragmentation of the flour is monitored with a high-speed camera, and the images are analysed to obtain the evolution of the number of fragments (N), their average size (A), and the FSD. Using the results from our image-analysis procedure, we find transient empirical laws for N, A and the exponent D of the power-law FSD as functions of the initial air pressure. We show that our experimental procedure is a promising tool for unravelling the complex physics of fragmentation during phreatomagmatic and phreatic eruptions.

  10. Neighbouring charge fragmentations in low energy fission

    International Nuclear Information System (INIS)

    Montoya, M.

    1986-10-01

    Shell and odd-even effects in fission have been largely studied until now. The structure in fragment mass, charge and kinetic energy distributions of fragments were interpreted as shell and even-odd effects. In this paper, we want to show that the discret change of fragment charge symmetry should produce also structures in those distribution. 19 refs

  11. Aspect Ratio Dependence of Impact Fragmentation

    International Nuclear Information System (INIS)

    Inaoka, H.; Toyosawa, E.; Takayasu, H.; Inaoka, H.

    1997-01-01

    A numerical model of three-dimensional impact fragmentation produces a power-law cumulative fragment mass distribution followed by a flat tail. The result is consistent with an experimental result in a recent paper by Meibom and Balslev [Phys. Rev. Lett. 76, 2492 (1996)]. Our numerical simulation also implies that the fragment mass distribution changes from a power law with a flat tail to a power law with a sudden cutoff, depending on the aspect ratio of the fractured object. copyright 1997 The American Physical Society

  12. Fragment-assisted hit investigation involving integrated HTS and fragment screening: Application to the identification of phosphodiesterase 10A (PDE10A) inhibitors.

    Science.gov (United States)

    Varnes, Jeffrey G; Geschwindner, Stefan; Holmquist, Christopher R; Forst, Janet; Wang, Xia; Dekker, Niek; Scott, Clay W; Tian, Gaochao; Wood, Michael W; Albert, Jeffrey S

    2016-01-01

    Fragment-based drug design (FBDD) relies on direct elaboration of fragment hits and typically requires high resolution structural information to guide optimization. In fragment-assisted drug discovery (FADD), fragments provide information to guide selection and design but do not serve as starting points for elaboration. We describe FADD and high-throughput screening (HTS) campaign strategies conducted in parallel against PDE10A where fragment hit co-crystallography was not available. The fragment screen led to prioritized fragment hits (IC50's ∼500μM), which were used to generate a hypothetical core scaffold. Application of this scaffold as a filter to HTS output afforded a 4μM hit, which, after preparation of a small number of analogs, was elaborated into a 16nM lead. This approach highlights the strength of FADD, as fragment methods were applied despite the absence of co-crystallographical information to efficiently identify a lead compound for further optimization. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Gluon fragmentation in T(1S) decays

    International Nuclear Information System (INIS)

    Bienlein, J.K.

    1983-05-01

    In T(1S) decays most observables (sphericity, charged multiplicity, photonic energy fraction, inclusive spectra) can be understood assuming that gluons fragment like quarks. New results from LENA use the (axis-independent) Fox-Wolfram moments for the photonic energy deposition. Continuum reactions show 'standard' Field-Feynman fragmentation. T(1S) decays show a significant difference in the photonic energy topology. It is more isotropic than with the Field-Feynman fragmentation scheme. Gluon fragmentation into isoscalar mesons (a la Peterson and Walsh) is excluded. But if one forces the leading particle to be isoscalar, one gets good agreement with the data. (orig.)

  14. Fragmentation of Relativistic 56Fe Nuclei in Emulsion

    International Nuclear Information System (INIS)

    Chernov, G.M.; Gulamov, K.G.; Gulyamov, U.G.; Navotny, V.Sh.; Petrov, N.V.; Svechnikova, L.N.; Jakobsson, B.; Oskarsson, A.; Otterlund, I.

    1983-03-01

    Experimental data on general characteristics of projectile fragments in inelastic interactions of relativistic 56 Fe nuclei in emulsion (multiplicities, transverse momentum distributions, azimuthal correlations) are presented and discussed. A strong dependence on the mass number of the projectile nucleus is observed for the transverse momenta of the emitted projectile fragments. These fragments exhibit an azimuthal asymmetry caused by the transverse motion of the fragmenting residue, but it is shown that this motion can be responsible only for a part of the increase in the average transverse momentum of the fragments with increasing mass of the projectile. (author)

  15. Percutaneous transhepatic fragmentation of gall stones and extraction of fragments

    International Nuclear Information System (INIS)

    Guenther, R.; Klose, K.; Schmidt, H.D.; Staritz, M.; Mainz Univ.; Mainz Univ.

    1983-01-01

    Attempts at percutaneous removal have been made in 13 patients with solitary and multiple intra- and extra-hepatic biliary duct stones measuring 5 to 30 mm. The stones were fragmented with a Dormia basket and the fragments removed transhepatically. In ten patients the procedure was successful, including one patient with multiple intra-hepatic stones. The procedure can be recommended for cases of calculous obstruction of biliary anastomoses or of stones which could not be removed by endoscopy, or where there is already biliary drainage being carried out, or in patients with a high opertive risk. In two patients, dilatation of the papilla was also carried out, in four patients a stenosis was dilated and in a further two patients, electro-incision of a stenosis was performed. (orig.) [de

  16. The role of fragmentation mechanism in large-scale vapor explosions

    International Nuclear Information System (INIS)

    Liu, Jie

    2003-01-01

    A non-equilibrium, multi-phase, multi-component code PROVER-I is developed for propagation phase of vapor explosion. Two fragmentation models are used. The hydrodynamic fragmentation model is the same as Fletcher's one. A new thermal fragmentation model is proposed with three kinds of time scale for modeling instant fragmentation, spontaneous nucleation fragmentation and normal boiling fragmentation. The role of fragmentation mechanisms is investigated by the simulations of the pressure wave propagation and energy conversion ratio of ex-vessel vapor explosion. The spontaneous nucleation fragmentation results in a much higher pressure peak and a larger energy conversion ratio than hydrodynamic fragmentation. The instant fragmentation gives a slightly larger energy conversion ratio than spontaneous nucleation fragmentation, and the normal boiling fragmentation results in a smaller energy conversion ratio. The detailed analysis of the structure of pressure wave makes it clear that thermal detonation exists only under the thermal fragmentation circumstance. The high energy conversion ratio is obtained in a small vapor volume fraction. However, in larger vapor volume fraction conditions, the vapor explosion is weak. In a large-scale vapor explosion, the hydrodynamic fragmentation is essential when the pressure wave becomes strong, so a small energy conversion ratio is expected. (author)

  17. Oregon State University nuclear chemistry progress report, August 1, 1989--August 1, 1990

    International Nuclear Information System (INIS)

    Loveland, W.D.

    1990-08-01

    This report discusses the following topics: the elements beyond uranium; the interaction of 21 MeV/nucleon 129 Xe with 197 Au; the interaction of 93 MeV/nucleon 36 Ar with 197 Au, participant-spectator physics; consistency test of two measures of linear momentum transfer; the interaction of ∼30 MeV/nucleon projectiles with 197 Au; gold target fragmentation by 800 GeV protons; target fragment mass distribution for the reaction of 13.3 GeV/nucleon 28 Si with 197 Au; momentum distributions of spallation products from the interaction of 400 MeV/nucleon 12 C with 197 Au; and pulse height defects for very low energy, very heavy ions

  18. Memory effects in nuclear fragmentation?

    International Nuclear Information System (INIS)

    Colonna, M.; Di Toro, M.; Guarnera, A.

    1994-01-01

    A general procedure to identify instability regions which lead to multifragmentation events is presented. The dominant mode at the instability point is determined from the knowledge of the mean properties (density and temperature) of the system at that point. For spinodal instabilities the dependence of fragment structures on the dynamical conditions is studied changing the beam energy and the considered equation of state. An important competition between two dynamical effects, expansion of the system and growth of fluctuations, is revealed. It is shown that in heavy-ion central collisions at medium energies memory effects of the configuration formed at the instability time could be observed in the final fragmentation pattern. Some hints towards a fully dynamical picture of fragmentation processes are finally suggested. ((orig.))

  19. Origin of fragments in multifragmentation reactions

    International Nuclear Information System (INIS)

    Zbiri, K.; Aichelin, J.

    2003-01-01

    Using the quantum molecular dynamics approach we have started analyzing the results of the recent INDRA experiments at GSI facilities. For the first time we could identify a midrapidity source in which fragments are formed from an almost identical fraction of projectile and target nucleons. In smaller systems we have found this source. Nevertheless the fragment spectra at small and large angles is completely determined by the dynamics. We discuss how fragments are formed in the different regions of phase space and what they tell us about the reaction mechanism. (authors)

  20. Gluon fragmentation into 3 PJ quarkonium

    International Nuclear Information System (INIS)

    Ma, J.P.

    1995-01-01

    The functions of the gluon fragmentation into 3 P j quarkonium are calculated to order α 2 s . With the recent progress in analysing quarkonium systems in QCD it is possible show how the so called divergence in the limit of the zero-binding energy, which is related to P-wave quarkonia, is treated correctly in the case of fragmentation functions. The obtained fragmentation functions satisfy explicitly at the order of α 2 s the Altarelli-Parisi equation and when z → 0 they behave as z -1 as expected. 19 refs., 7 figs

  1. Origin of fragments in multifragmentation reactions

    International Nuclear Information System (INIS)

    Zbiri, K.; Aichelin, J.

    2005-01-01

    Using the quantum molecular dynamics approach we have started to analyze the results of the recent INDRA experiments at GSI experiments. For the first time we could identify a midrapidity source in which fragments are formed from a almost identical fraction of projectile and target nucleons. In smaller systems we have not found this source. Nevertheless the fragment spectra at small and large angles are completely determined by the dynamics. We discuss how fragments are formed in the different regions of phase space and what they tell us about the reaction mechanism. (author)

  2. Fuel fragmentation data review and separate effects testing

    International Nuclear Information System (INIS)

    Yueh, Ken. H.; Snis, N.; Mitchell, D.; Munoz-Reja, C.

    2014-01-01

    A simple alternative test has been developed to study the fuel fragmentation process at loss of coolant accident (LOCA) temperatures. The new test heats a short section of fuel, approximately two pellets worth of material, in a tube furnace open to air. An axial slit is cut in the test sample cladding to reduce radial restraint and to simulate ballooned condition. The tube furnace allows the fuel fragmentation process be observed during the experiment. The test was developed as a simple alternative so large number of tests could be conducted quickly and efficiently to identify key variables that influence fuel fragmentation and to zeroing on the fuel fragmentation burn-up threshold. Several tests were conducted, using fuel materials from fuel rods that were used in earlier integral tests to benchmark and validate the test technique. High burn-up fuel materials known to be above the fragmentation threshold was used to evaluate the fragmentation process as a function of temperature. Even with an axial slit and both ends open, no significant fuel detachment/release was detected until above 750°C. Additional tests were conducted with fuel materials at burn-ups closer to the fuel fragmentation burn-up threshold. Results from these tests indicate a minor power history effect on the fuel fragmentation burn-up threshold. An evaluation of available literature and data generated from this work suggest a fuel fragmentation burn-up threshold between 70 and 75 GWd/MTU. (author)

  3. Non-extensive statistical aspects of clustering and nuclear multi-fragmentation

    International Nuclear Information System (INIS)

    Calboreanu, A.

    2002-01-01

    Recent developments concerning an application of the non-extensive Tsalis statistics to describe clustering phenomena is briefly presented. Cluster formation is a common feature of a large number of physical phenomena encountered in molecular and nuclear physics, astrophysics, condensed matter and biophysics. Common to all these is the large number of degrees of freedom, thus justifying a statistical approach. However the conventional statistical mechanics paradigm seems to fail in dealing with clustering. Whether this is due to the prevalence of complex dynamical constrains, or it is a manifestation of new statistics is a subject of considerable interest, which was intensively debated during the last few years. Tsalis conjecture has proved extremely appealing due to its rather elegant and transparent basic arguments. We present here evidence for its adequacy for the study of a large class of physical phenomena related to cluster formation. An application to nuclear multi-fragmentation is presented. (author)

  4. High-throughput fragment screening by affinity LC-MS.

    Science.gov (United States)

    Duong-Thi, Minh-Dao; Bergström, Maria; Fex, Tomas; Isaksson, Roland; Ohlson, Sten

    2013-02-01

    Fragment screening, an emerging approach for hit finding in drug discovery, has recently been proven effective by its first approved drug, vemurafenib, for cancer treatment. Techniques such as nuclear magnetic resonance, surface plasmon resonance, and isothemal titration calorimetry, with their own pros and cons, have been employed for screening fragment libraries. As an alternative approach, screening based on high-performance liquid chromatography separation has been developed. In this work, we present weak affinity LC/MS as a method to screen fragments under high-throughput conditions. Affinity-based capillary columns with immobilized thrombin were used to screen a collection of 590 compounds from a fragment library. The collection was divided into 11 mixtures (each containing 35 to 65 fragments) and screened by MS detection. The primary screening was performed in 3500 fragments per day). Thirty hits were defined, which subsequently entered a secondary screening using an active site-blocked thrombin column for confirmation of specificity. One hit showed selective binding to thrombin with an estimated dissociation constant (K (D)) in the 0.1 mM range. This study shows that affinity LC/MS is characterized by high throughput, ease of operation, and low consumption of target and fragments, and therefore it promises to be a valuable method for fragment screening.

  5. Biological effectiveness of high-energy protons - Target fragmentation

    International Nuclear Information System (INIS)

    Cucinotta, F.A.; Katz, R.; Wilson, J.W.; Townsend, L.W.; Shinn, J.; Hajnal, F.

    1991-01-01

    High-energy protons traversing tissue produce local sources of high-linear-energy-transfer ions through nuclear fragmentation. The contribution of these target fragments to the biological effectiveness of high-energy protons using the cellular track model is examined. The effects of secondary ions are treated in terms of the production collision density using energy-dependent parameters from a high-energy fragmentation model. Calculations for mammalian cell cultures show that at high dose, at which intertrack effects become important, protons deliver damage similar to that produced by gamma rays, and with fragmentation the relative biological effectiveness (RBE) of protons increases moderately from unity. At low dose, where sublethal damage is unimportant, the contribution from target fragments dominates, causing the proton effectiveness to be very different from that of gamma rays with a strongly fluence-dependent RBE. At high energies, the nuclear fragmentation cross sections become independent of energy. This leads to a plateau in the proton single-particle-action cross section, below 1 keV/micron, since the target fragments dominate. 29 refs

  6. Bootstrap embedding: An internally consistent fragment-based method

    Energy Technology Data Exchange (ETDEWEB)

    Welborn, Matthew; Tsuchimochi, Takashi; Van Voorhis, Troy [Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139 (United States)

    2016-08-21

    Strong correlation poses a difficult problem for electronic structure theory, with computational cost scaling quickly with system size. Fragment embedding is an attractive approach to this problem. By dividing a large complicated system into smaller manageable fragments “embedded” in an approximate description of the rest of the system, we can hope to ameliorate the steep cost of correlated calculations. While appealing, these methods often converge slowly with fragment size because of small errors at the boundary between fragment and bath. We describe a new electronic embedding method, dubbed “Bootstrap Embedding,” a self-consistent wavefunction-in-wavefunction embedding theory that uses overlapping fragments to improve the description of fragment edges. We apply this method to the one dimensional Hubbard model and a translationally asymmetric variant, and find that it performs very well for energies and populations. We find Bootstrap Embedding converges rapidly with embedded fragment size, overcoming the surface-area-to-volume-ratio error typical of many embedding methods. We anticipate that this method may lead to a low-scaling, high accuracy treatment of electron correlation in large molecular systems.

  7. Fragmentation of molten core material by sodium

    International Nuclear Information System (INIS)

    Chu, T.Y.

    1982-01-01

    A series of scoping experiments was performed to study the fragmentation of prototypic high temperature melts in sodium. The quantity of melt involved was at least one order of magnitude larger than previous experiments. Two modes of contact were used: melt streaming into sodium and sodium into melt. The average bulk fragment size distribution was found to be in the range of previous data and the average size distribution was found to be insensitive to mode of contact. SEM studies showed that the metal component typically fragmented in the molten phase while the oxide component fragmented in the solid phase. For UO 2 -ZrO 2 /stainless steel melts no sigificant spatial separation of the metal and oxide was observed. The fragment size distribution was stratified vertically in the debris bed in all cases. While the bulk fragment size showed generally consistent trends, the individual experiments were sufficiently different to cause different degrees of stratification in the debris bed. For the highly stratified beds the permeability can decrease by as much as a factor of 20 from the bottom to the top of the bed

  8. Quark fragmentation functions in NJL-jet model

    Science.gov (United States)

    Bentz, Wolfgang; Matevosyan, Hrayr; Thomas, Anthony

    2014-09-01

    We report on our studies of quark fragmentation functions in the Nambu-Jona-Lasinio (NJL) - jet model. The results of Monte-Carlo simulations for the fragmentation functions to mesons and nucleons, as well as to pion and kaon pairs (dihadron fragmentation functions) are presented. The important role of intermediate vector meson resonances for those semi-inclusive deep inelastic production processes is emphasized. Our studies are very relevant for the extraction of transverse momentum dependent quark distribution functions from measured scattering cross sections. We report on our studies of quark fragmentation functions in the Nambu-Jona-Lasinio (NJL) - jet model. The results of Monte-Carlo simulations for the fragmentation functions to mesons and nucleons, as well as to pion and kaon pairs (dihadron fragmentation functions) are presented. The important role of intermediate vector meson resonances for those semi-inclusive deep inelastic production processes is emphasized. Our studies are very relevant for the extraction of transverse momentum dependent quark distribution functions from measured scattering cross sections. Supported by Grant in Aid for Scientific Research, Japanese Ministry of Education, Culture, Sports, Science and Technology, Project No. 20168769.

  9. Fragment-based drug discovery using rational design.

    Science.gov (United States)

    Jhoti, H

    2007-01-01

    Fragment-based drug discovery (FBDD) is established as an alternative approach to high-throughput screening for generating novel small molecule drug candidates. In FBDD, relatively small libraries of low molecular weight compounds (or fragments) are screened using sensitive biophysical techniques to detect their binding to the target protein. A lower absolute affinity of binding is expected from fragments, compared to much higher molecular weight hits detected by high-throughput screening, due to their reduced size and complexity. Through the use of iterative cycles of medicinal chemistry, ideally guided by three-dimensional structural data, it is often then relatively straightforward to optimize these weak binding fragment hits into potent and selective lead compounds. As with most other lead discovery methods there are two key components of FBDD; the detection technology and the compound library. In this review I outline the two main approaches used for detecting the binding of low affinity fragments and also some of the key principles that are used to generate a fragment library. In addition, I describe an example of how FBDD has led to the generation of a drug candidate that is now being tested in clinical trials for the treatment of cancer.

  10. Critical Features of Fragment Libraries for Protein Structure Prediction.

    Science.gov (United States)

    Trevizani, Raphael; Custódio, Fábio Lima; Dos Santos, Karina Baptista; Dardenne, Laurent Emmanuel

    2017-01-01

    The use of fragment libraries is a popular approach among protein structure prediction methods and has proven to substantially improve the quality of predicted structures. However, some vital aspects of a fragment library that influence the accuracy of modeling a native structure remain to be determined. This study investigates some of these features. Particularly, we analyze the effect of using secondary structure prediction guiding fragments selection, different fragments sizes and the effect of structural clustering of fragments within libraries. To have a clearer view of how these factors affect protein structure prediction, we isolated the process of model building by fragment assembly from some common limitations associated with prediction methods, e.g., imprecise energy functions and optimization algorithms, by employing an exact structure-based objective function under a greedy algorithm. Our results indicate that shorter fragments reproduce the native structure more accurately than the longer. Libraries composed of multiple fragment lengths generate even better structures, where longer fragments show to be more useful at the beginning of the simulations. The use of many different fragment sizes shows little improvement when compared to predictions carried out with libraries that comprise only three different fragment sizes. Models obtained from libraries built using only sequence similarity are, on average, better than those built with a secondary structure prediction bias. However, we found that the use of secondary structure prediction allows greater reduction of the search space, which is invaluable for prediction methods. The results of this study can be critical guidelines for the use of fragment libraries in protein structure prediction.

  11. Developments in SPR Fragment Screening.

    Science.gov (United States)

    Chavanieu, Alain; Pugnière, Martine

    2016-01-01

    Fragment-based approaches have played an increasing role alongside high-throughput screening in drug discovery for 15 years. The label-free biosensor technology based on surface plasmon resonance (SPR) is now sensitive and informative enough to serve during primary screens and validation steps. In this review, the authors discuss the role of SPR in fragment screening. After a brief description of the underlying principles of the technique and main device developments, they evaluate the advantages and adaptations of SPR for fragment-based drug discovery. SPR can also be applied to challenging targets such as membrane receptors and enzymes. The high-level of immobilization of the protein target and its stability are key points for a relevant screening that can be optimized using oriented immobilized proteins and regenerable sensors. Furthermore, to decrease the rate of false negatives, a selectivity test may be performed in parallel on the main target bearing the binding site mutated or blocked with a low-off-rate ligand. Fragment-based drug design, integrated in a rational workflow led by SPR, will thus have a predominant role for the next wave of drug discovery which could be greatly enhanced by new improvements in SPR devices.

  12. Transition from collective to participant-spectator mechanisms in the reaction Kr + Au at 43 MeV/u

    International Nuclear Information System (INIS)

    Rudolf, G.; Adloff, J.C.; Bilwes, B.; Bilwes, R.; Glaser, M.; Scheibling, F.; Stuttge, L.; Ferrero, J.L.

    1989-01-01

    This talk presents some of the most significant results already obtained from two complementary experiments on the reaction Kr + Au at 43 MeV/u. These experiments were performed with the help of the four charged-particle multidetectors operating at Ganil. The analysis concentrates on double and higher order coincidences between intermediate mass fragments among which at least one can be considered as a fragment of the projectile. The results presented here are the following: i) for the most peripheral collisions, the mechanism is very similar to that of partly damped deep-inelastic reactions known from low bombarding energy studies; ii) for intermediate impact parameters, when several hundreds of MeV are dissipated, the target emits intermediate mass fragments; iii) this emission is not an equilibrated evaporation, but is localized between the target and the projectile and occurs on a time-scale comparable to the interaction time; and iiii) for the most central collisions, up to 1.5 GeV may be dissipated and a separate participant zone is created

  13. The VERDI fission fragment spectrometer

    Directory of Open Access Journals (Sweden)

    Frégeau M.O.

    2013-12-01

    Full Text Available The VERDI time-of-flight spectrometer is dedicated to measurements of fission product yields and of prompt neutron emission data. Pre-neutron fission-fragment masses will be determined by the double time-of-flight (TOF technique. For this purpose an excellent time resolution is required. The time of flight of the fragments will be measured by electrostatic mirrors located near the target and the time signal coming from silicon detectors located at 50 cm on both sides of the target. This configuration, where the stop detector will provide us simultaneously with the kinetic energy of the fragment and timing information, significantly limits energy straggling in comparison to legacy experimental setup where a thin foil was usually used as a stop detector. In order to improve timing resolution, neutron transmutation doped silicon will be used. The high resistivity homogeneity of this material should significantly improve resolution in comparison to standard silicon detectors. Post-neutron fission fragment masses are obtained form the time-of-flight and the energy signal in the silicon detector. As an intermediary step a diamond detector will also be used as start detector located very close to the target. Previous tests have shown that poly-crystalline chemical vapour deposition (pCVD diamonds provides a coincidence time resolution of 150 ps not allowing complete separation between very low-energy fission fragments, alpha particles and noise. New results from using artificial single-crystal diamonds (sCVD show similar time resolution as from pCVD diamonds but also sufficiently good energy resolution.

  14. A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection.

    Directory of Open Access Journals (Sweden)

    Krystal Cole

    Full Text Available High throughput screening technologies such as acoustic droplet ejection (ADE greatly increase the rate at which X-ray diffraction data can be acquired from crystals. One promising high throughput screening application of ADE is to rapidly combine protein crystals with fragment libraries. In this approach, each fragment soaks into a protein crystal either directly on data collection media or on a moving conveyor belt which then delivers the crystals to the X-ray beam. By simultaneously handling multiple crystals combined with fragment specimens, these techniques relax the automounter duty-cycle bottleneck that currently prevents optimal exploitation of third generation synchrotrons. Two factors limit the speed and scope of projects that are suitable for fragment screening using techniques such as ADE. Firstly, in applications where the high throughput screening apparatus is located inside the X-ray station (such as the conveyor belt system described above, the speed of data acquisition is limited by the time required for each fragment to soak into its protein crystal. Secondly, in applications where crystals are combined with fragments directly on data acquisition media (including both of the ADE methods described above, the maximum time that fragments have to soak into crystals is limited by evaporative dehydration of the protein crystals during the fragment soak. Here we demonstrate that both of these problems can be minimized by using small crystals, because the soak time required for a fragment hit to attain high occupancy depends approximately linearly on crystal size.

  15. Hydrothermal Atomic Force Microscopy Investigation of Barite Growth: Role of Spectator Ions in Elementary Step Edge Growth Kinetics and Hillock Morphology [Supporting Information Only

    Energy Technology Data Exchange (ETDEWEB)

    Jindra, Sarah A. [Wright State Univ., Dayton, OH (United States); Bertagni, Angela L. [Wright State Univ., Dayton, OH (United States); Bracco, Jacquelyn N. [Wright State Univ., Dayton, OH (United States); Argonne National Lab. (ANL), Argonne, IL (United States); Higgins, Steven R. [Wright State Univ., Dayton, OH (United States)

    2017-09-25

    Here, to better understand the role of spectator ions in barite growth, the kinetics of step edge growth on barite (001) surfaces were studied under various salt solutions. Hydrothermal atomic force microscopy (HAFM) was used to investigate the effect of background electrolytes (NaCl, NaBr, and NaNO3) as a function of saturation index and ionic strength (I) on barite growth sourced at dislocations at 108 °C. Results demonstrate that hillock morphology is affected by I, as well as type of anion, where the prevalence of steps aligned on the [010] direction is highest under Cl. There is a modest increase in kinetic coefficient of 55–130% with a 10-fold increase in I for each salt. In comparing the kinetic coefficients of the salts at low ionic strength (0.01 M), there is a moderate difference, suggesting that the anion may play a role in barium attachment.

  16. Study of Light Ion Collisions

    CERN Multimedia

    2002-01-01

    Inelastic and elastic pd, dd, p@a and @a@a interactions are studied at a nucleon-nucleon cm energy @]s^n^n = 31~GeV using the Split-Field-Magnet detector. The two forward telescopes have been upgraded by two calorimeters to tag spectator neutrons and by two MWPCs for improved detection of charged nuclear fragments. Several selective triggers are planned in addition to the minimum-bias trigger: 1) high p^t single hadron at 10|0, 20|0 and 45|0; 2) central particle production together with unfragmented projectiles; 3) nuclear break-up without particle production; 4) elastic interactions. This experiment is an extension of the @a-run in 1980; the new one will benefit from the direct comparisons of @a@a, dd, @ap and dp interactions; from expected higher integrated luminosity for @a@a interactions; the upgrading of the spectator tagging capability and the new high p^t triggers installed by R41

  17. Whole study of nuclear matter collective motion in central collisions of heavy ions of the FOPI detector

    International Nuclear Information System (INIS)

    Bendarag, A.

    1999-01-01

    In this work we study the collective phenomena in the central collisions of heavy ions for the Au + Au, Xe + CsI and Ni + Ni systems at incident energies from 150 to 400 MeV/nucleon with the data of the FOPI detector. In order to describe completely the flow of the nuclear matter, we fit the double differential momentum distributions with two-dimensional Gaussian. We study the characteristic parameters of the collective flow (flow range, aspect ratios, flow parameter) versus the charge and the mass of the fragments as well as the incident energy and the centrality of the collisions. The transverse energy is used for selecting the central collisions. The method of the Gaussian fits requires also to reconstruct the reaction plane of the event. Then we correct the parameters for the finite number of particles effects and account for the influence of the acceptance of the detector. We confirm the importance of the thermal motion for the light charge or mass fragments and, conversely, the predominance of the collective motion for the heavy fragments. A common flow angle for all the types of particles is highlighted for the first time, demonstrating the power of the method of the Gaussian fits; The evolution of the other parameters confirms the observations done with other methods of flow analysis. These results should contribute to put constraints on the collision models and to enlarge our knowledge of the properties of the nuclear matter. (author)

  18. An Enumerative Combinatorics Model for Fragmentation Patterns in RNA Sequencing Provides Insights into Nonuniformity of the Expected Fragment Starting-Point and Coverage Profile.

    Science.gov (United States)

    Prakash, Celine; Haeseler, Arndt Von

    2017-03-01

    RNA sequencing (RNA-seq) has emerged as the method of choice for measuring the expression of RNAs in a given cell population. In most RNA-seq technologies, sequencing the full length of RNA molecules requires fragmentation into smaller pieces. Unfortunately, the issue of nonuniform sequencing coverage across a genomic feature has been a concern in RNA-seq and is attributed to biases for certain fragments in RNA-seq library preparation and sequencing. To investigate the expected coverage obtained from fragmentation, we develop a simple fragmentation model that is independent of bias from the experimental method and is not specific to the transcript sequence. Essentially, we enumerate all configurations for maximal placement of a given fragment length, F, on transcript length, T, to represent every possible fragmentation pattern, from which we compute the expected coverage profile across a transcript. We extend this model to incorporate general empirical attributes such as read length, fragment length distribution, and number of molecules of the transcript. We further introduce the fragment starting-point, fragment coverage, and read coverage profiles. We find that the expected profiles are not uniform and that factors such as fragment length to transcript length ratio, read length to fragment length ratio, fragment length distribution, and number of molecules influence the variability of coverage across a transcript. Finally, we explore a potential application of the model where, with simulations, we show that it is possible to correctly estimate the transcript copy number for any transcript in the RNA-seq experiment.

  19. Experimental and theoretical study of the fragment production in the Xe+Sn collisions from 25 to 150 A.MeV

    International Nuclear Information System (INIS)

    Hudan, Sylvie

    2001-01-01

    In order to understand the fragment production which occurs in heavy ion collisions at intermediate energies we have performed in this work an experimental and theoretical study of multifragmentation. The set of data obtained with the INDRA detector over a wide range of incident energy for the Xe+Sn system allows to perform a study of central collisions which shows that the maximum of fragment production is around 65 MeV/n of incident energy. A more detailed study of central collisions from 32 to 50 MeV/n of bombarding energy, based on fragment/particle correlation functions, has helped to determine the characteristics of primary fragments produced by the collision. The excitation energy of the se fragments shows a saturation at a value of 3 MeV/n beyond 39 MeV/n of beam energy and the evaporated particles represent less than 40% (23% at 50 MeV/n) of all light charged particles, which indicates the importance of the collision dynamics. Calculations with the antisymmetrized molecular dynamics model AMD have been made in order to study the role of dynamics and the time evolution of the collision. The simulations are in good agreement with the experimental data, namely for the most central collisions at 50 and 100 MeV/n of beam energy for the Xe+Sn system. In this scope some developments have been necessary so that the diffusion properties of nucleons in nuclear matter can be better taken into account. The calculations allowed to locate the fragment time production between 100 and 200 fm/c in central collisions at 50 MeV/n of beam energy. Furthermore they showed a transparency effect even in the most central collisions. The comparison with the experimental data show that this effect is slightly overestimated in the calculations. (author) [fr

  20. Effective Fragmentation and Flyrock Control Strategies at Quarries

    Directory of Open Access Journals (Sweden)

    Sedat Esen

    2017-01-01

    Full Text Available This paper presents the effective fragmentation and flyrock control strategies that could be applied at quarries to improve the productivity and safety. Fragmentation measurement and modelling as well as a comprehensive drill and blast audit are essential for improving the fragmentation. Face profiling and bore tracking are good tools to manage the ―as-designed‖ and ―as-drilled‖ conditions to get reasonable fragmentation from face burden zone and minimise the flyrock risk. In general, a large scatter in fragmentation data was observed at sites and the causes should be analysed by a detailed root-cause analysis technique. Two case studies were presented in this paper showing some of the effective fragmentation strategies. Finally, a flyrock model was shown to determine the safe blast exclusion zone for the mining equipment and personnel. Some key guidelines were suggested to minimise the occurrence of the flyrock.

  1. Release and characteristics of fungal fragments in various conditions

    Energy Technology Data Exchange (ETDEWEB)

    Mensah-Attipoe, Jacob [Department of Environmental Science, University of Eastern Finland, Yliopistonranta 1D, P. O. Box 1627, FI-70211 Kuopio (Finland); Saari, Sampo [Department of Physics, Tampere University of Technology, Korkeakoulunkatu 3, 33720 Tampere (Finland); Veijalainen, Anna-Maria; Pasanen, Pertti [Department of Environmental Science, University of Eastern Finland, Yliopistonranta 1D, P. O. Box 1627, FI-70211 Kuopio (Finland); Keskinen, Jorma [Department of Physics, Tampere University of Technology, Korkeakoulunkatu 3, 33720 Tampere (Finland); Leskinen, Jari T.T. [SIB Labs, University of Eastern Finland, Yliopistonranta 1E, P. O. Box 1627, FI-70211, Kuopio (Finland); Reponen, Tiina, E-mail: reponeta@ucmail.uc.edu [Department of Environmental Science, University of Eastern Finland, Yliopistonranta 1D, P. O. Box 1627, FI-70211 Kuopio (Finland); Department of Environmental Health, University of Cincinnati, P.O. Box 670056, Cincinnati, OH 45267-0056 (United States)

    2016-03-15

    Intact spores and submicrometer size fragments are released from moldy building materials during growth and sporulation. It is unclear whether all fragments originate from fungal growth or if small pieces of building materials are also aerosolized as a result of microbial decomposition. In addition, particles may be formed through nucleation from secondary metabolites of fungi, such as microbial volatile organic compounds (MVOCs). In this study, we used the elemental composition of particles to characterize the origin of submicrometer fragments released from materials contaminated by fungi. Particles from three fungal species (Aspergillus versicolor, Cladosporium cladosporioides and Penicillium brevicompactum), grown on agar, wood and gypsum board were aerosolized using the Fungal Spore Source Strength Tester (FSSST) at three air velocities (5, 16 and 27 m/s). Released spores (optical size, d{sub p} ≥ 0.8 μm) and fragments (d{sub p} ≤ 0.8 μm) were counted using direct-reading optical aerosol instruments. Particles were also collected on filters, and their morphology and elemental composition analyzed using scanning electron microscopes (SEMs) coupled with an Energy-Dispersive X-ray spectroscopy (EDX). Among the studied factors, air velocity resulted in the most consistent trends in the release of fungal particles. Total concentrations of both fragments and spores increased with an increase in air velocity for all species whereas fragment–spore (F/S) ratios decreased. EDX analysis showed common elements, such as C, O, Mg and Ca, for blank material samples and fungal growth. However, N and P were exclusive to the fungal growth, and therefore were used to differentiate biological fragments from non-biological ones. Our results indicated that majority of fragments contained N and P. Because we observed increased release of fragments with increased air velocities, nucleation of MVOCs was likely not a relevant process in the formation of fungal fragments. Based

  2. Graph Theory. 1. Fragmentation of Structural Graphs

    Directory of Open Access Journals (Sweden)

    Lorentz JÄNTSCHI

    2002-12-01

    Full Text Available The investigation of structural graphs has many fields of applications in engineering, especially in applied sciences like as applied chemistry and physics, computer sciences and automation, electronics and telecommunication. The main subject of the paper is to express fragmentation criteria in graph using a new method of investigation: terminal paths. Using terminal paths are defined most of the fragmentation criteria that are in use in molecular topology, but the fields of applications are more generally than that, as I mentioned before. Graphical examples of fragmentation are given for every fragmentation criteria. Note that all fragmentation is made with a computer program that implements a routine for every criterion.[1] A web routine for tracing all terminal paths in graph can be found at the address: http://vl.academicdirect.ro/molecular_topology/tpaths/ [1] M. V. Diudea, I. Gutman, L. Jäntschi, Molecular Topology, Nova Science, Commack, New York, 2001, 2002.

  3. Route to three-dimensional fragments using diversity-oriented synthesis.

    Science.gov (United States)

    Hung, Alvin W; Ramek, Alex; Wang, Yikai; Kaya, Taner; Wilson, J Anthony; Clemons, Paul A; Young, Damian W

    2011-04-26

    Fragment-based drug discovery (FBDD) has proven to be an effective means of producing high-quality chemical ligands as starting points for drug-discovery pursuits. The increasing number of clinical candidate drugs developed using FBDD approaches is a testament of the efficacy of this approach. The success of fragment-based methods is highly dependent on the identity of the fragment library used for screening. The vast majority of FBDD has centered on the use of sp(2)-rich aromatic compounds. An expanded set of fragments that possess more 3D character would provide access to a larger chemical space of fragments than those currently used. Diversity-oriented synthesis (DOS) aims to efficiently generate a set of molecules diverse in skeletal and stereochemical properties. Molecules derived from DOS have also displayed significant success in the modulation of function of various "difficult" targets. Herein, we describe the application of DOS toward the construction of a unique set of fragments containing highly sp(3)-rich skeletons for fragment-based screening. Using cheminformatic analysis, we quantified the shapes and physical properties of the new 3D fragments and compared them with a database containing known fragment-like molecules.

  4. Fragment-based discovery of a potent NAMPT inhibitor.

    Science.gov (United States)

    Korepanova, Alla; Longenecker, Kenton L; Pratt, Steve D; Panchal, Sanjay C; Clark, Richard F; Lake, Marc; Gopalakrishnan, Sujatha M; Raich, Diana; Sun, Chaohong; Petros, Andrew M

    2017-12-12

    NAMPT expression is elevated in many cancers, making this protein a potential target for anticancer therapy. We have carried out both NMR based and TR-FRET based fragment screens against human NAMPT and identified six novel binders with a range of potencies. Co-crystal structures were obtained for two of the fragments bound to NAMPT while for the other four fragments force-field driven docking was employed to generate a bound pose. Based on structural insights arising from comparison of the bound fragment poses to that of bound FK866 we were able to synthetically elaborate one of the fragments into a potent NAMPT inhibitor. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Light fragment formation at intermediate energies

    International Nuclear Information System (INIS)

    Boal, D.H.

    1982-03-01

    This paper concerns itself mainly with the production of energetic protons and light fragments at wide angles. The experiments point to nucleon emission in proton-induced reactions as involving a mechanism in which the observed nucleon is directly knocked out of the nucleus. A similar feature seems to be required to explain (p,F) and (e,F) reactions: an energetic nucleon is produced in one scattering of the projectile, and the struck nucleon subsequently loses some of its energy as it traverses the remaining part of the nucleus, gathering up other nucleons as it goes, to become a fragment. This is what one might call the extreme snowball model, and a more accurate description probably involves multiple scattering of the projectile in addition to the extreme snowball contribution. This will be particularly true for fragments in the mass 6 to 9 region. This scenario also appears to apply to deuteron-induced fragment production. However, for alpha-induced reactions it would appear that the nucleons forming a fragment can originate from collisions involving different incident nucleons in the projectile. For heavy ions, this effect is even stronger, and the snowball contribution is greatly reduced compared to that of the traditional coalescence model

  6. Measuring the temperature of hot nuclear fragments

    International Nuclear Information System (INIS)

    Wuenschel, S.; Bonasera, A.; May, L.W.; Souliotis, G.A.; Tripathi, R.; Galanopoulos, S.; Kohley, Z.; Hagel, K.; Shetty, D.V.; Huseman, K.; Soisson, S.N.; Stein, B.C.; Yennello, S.J.

    2010-01-01

    A new thermometer based on fragment momentum fluctuations is presented. This thermometer exhibited residual contamination from the collective motion of the fragments along the beam axis. For this reason, the transverse direction has been explored. Additionally, a mass dependence was observed for this thermometer. This mass dependence may be the result of the Fermi momentum of nucleons or the different properties of the fragments (binding energy, spin, etc.) which might be more sensitive to different densities and temperatures of the exploding fragments. We expect some of these aspects to be smaller for protons (and/or neutrons); consequently, the proton transverse momentum fluctuations were used to investigate the temperature dependence of the source.

  7. DebriSat - A Planned Laboratory-Based Satellite Impact Experiment for Breakup Fragment Characterization

    Science.gov (United States)

    Liou, J.-C.; Fitz-Coy, N.; Werremeyer, M.; Huynh, T.; Voelker, M.; Opiela, J.

    2012-01-01

    DebriSat is a planned laboratory ]based satellite hypervelocity impact experiment. The goal of the project is to characterize the orbital debris that would be generated by a hypervelocity collision involving a modern satellite in low Earth orbit (LEO). The DebriSat project will update and expand upon the information obtained in the 1992 Satellite Orbital Debris Characterization Impact Test (SOCIT), which characterized the breakup of a 1960 's US Navy Transit satellite. There are three phases to this project: the design and fabrication of an engineering model representing a modern, 50-cm/50-kg class LEO satellite known as DebriSat; conduction of a laboratory-based hypervelocity impact to catastrophically break up the satellite; and characterization of the properties of breakup fragments down to 2 mm in size. The data obtained, including fragment size, area ]to ]mass ratio, density, shape, material composition, optical properties, and radar cross ]section distributions, will be used to supplement the DoD fs and NASA fs satellite breakup models to better describe the breakup outcome of a modern satellite. Updated breakup models will improve mission planning, environmental models, and event response. The DebriSat project is sponsored by the Air Force fs Space and Missile Systems Center and the NASA Orbital Debris Program Office. The design and fabrication of DebriSat is led by University of Florida with subject matter experts f support from The Aerospace Corporation. The major milestones of the project include the complete fabrication of DebriSat by September 2013, the hypervelocity impact of DebriSat at the Air Force fs Arnold Engineering Development Complex in early 2014, and fragment characterization and data analyses in late 2014.

  8. The Role of Nuclear Fragmentation in Particle Therapy and Space Radiation Protection.

    Science.gov (United States)

    Zeitlin, Cary; La Tessa, Chiara

    2016-01-01

    The transport of the so-called HZE particles (those having high charge, Z, and energy, E) through matter is crucially important both in space radiation protection and in the clinical setting where heavy ions are used for cancer treatment. HZE particles are usually considered those having Z > 1, though sometimes Z > 2 is meant. Transport physics is governed by two types of interactions, electromagnetic (ionization energy loss) and nuclear. Models of transport, such as those used in treatment planning and space mission planning must account for both effects in detail. The theory of electromagnetic interactions is well developed, but nucleus-nucleus collisions are so complex that no fundamental physical theory currently describes them. Instead, interaction models are generally anchored to experimental data, which in some areas are far from complete. The lack of fundamental physics knowledge introduces uncertainties in the calculations of exposures and their associated risks. These uncertainties are greatly compounded by the much larger uncertainties in biological response to HZE particles. In this article, we discuss the role of nucleus-nucleus interactions in heavy charged particle therapy and in deep space, where astronauts will receive a chronic low dose from galactic cosmic rays (GCRs) and potentially higher short-term doses from sporadic, unpredictable solar energetic particles (SEPs). GCRs include HZE particles; SEPs typically do not and we, therefore, exclude them from consideration in this article. Nucleus-nucleus collisions can result in the breakup of heavy ions into lighter ions. In space, this is generally beneficial because dose and dose equivalent are, on the whole, reduced in the process. The GCRs can be considered a radiation field with a significant high-LET component; when they pass through matter, the high-LET component is attenuated, at the cost of a slight increase in the low-LET component. Not only are the standard measures of risk

  9. QGP and Modified Jet Fragmentation

    International Nuclear Information System (INIS)

    Wang, Xin-Nian

    2005-01-01

    Recent progresses in the study of jet modification in hotmedium and their consequences in high-energy heavy-ion collisions are reviewed. In particular, I will discuss energy loss for propagating heavy quarks and the resulting modified fragmentation function. Medium modification of the parton fragmentation function due to quark recombination are formulated within finite temperature field theory and their implication on the search for deconfined quark-gluon plasma is also discussed

  10. Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry.

    Science.gov (United States)

    Mondal, Milon; Radeva, Nedyalka; Fanlo-Virgós, Hugo; Otto, Sijbren; Klebe, Gerhard; Hirsch, Anna K H

    2016-08-01

    Fragment-based drug design (FBDD) affords active compounds for biological targets. While there are numerous reports on FBDD by fragment growing/optimization, fragment linking has rarely been reported. Dynamic combinatorial chemistry (DCC) has become a powerful hit-identification strategy for biological targets. We report the synergistic combination of fragment linking and DCC to identify inhibitors of the aspartic protease endothiapepsin. Based on X-ray crystal structures of endothiapepsin in complex with fragments, we designed a library of bis-acylhydrazones and used DCC to identify potent inhibitors. The most potent inhibitor exhibits an IC50 value of 54 nm, which represents a 240-fold improvement in potency compared to the parent hits. Subsequent X-ray crystallography validated the predicted binding mode, thus demonstrating the efficiency of the combination of fragment linking and DCC as a hit-identification strategy. This approach could be applied to a range of biological targets, and holds the potential to facilitate hit-to-lead optimization. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  11. Relationship between Statistical and Dynamical properties of fragments produced at Fermi Energy in Heavy ion collisions: ng

    International Nuclear Information System (INIS)

    Lehaut, G.

    2009-10-01

    The properties of the fragments produced in heavy-ion collisions around the Fermi energy have been studied through the isospin degree of freedom. First, a theoretical approach based on a lattice gas model with two types of particles (neutron,proton) interacting by an isospin dependent and Coulomb interactions was developed. The study of the phase diagram shows that this system presents three different phases (liquid, gas, fission). In the liquid and gas phases, the energy of the system was described by a density functional, where the temperature dependence acts only on the density. The symmetry term of this functional was related to the isotopic content of the biggest fragment via an iso-scaling analysis. Secondly a systematic study of the stopping power of the nuclear matter and isospin equilibration of light particles in the most violent collisions was carried out using the experimental data taken by the INDRA multidetector at GANIL and GSI. Two stopping power regimes appear; at low energy (< 40 MeV/A) the stopping power decreases with increasing beam energy, whereas at high energy the stopping power is governed by the quantity of matter along the beam direction. An other study has been focused on the Xe+Sn reaction at 32 and 45 MeV/A with different isospin systems. The separation of three different reaction mechanisms by use of a principal component analysis allowed us to observe that the isospin content of light particles seems to be independent on the mechanism, but depends on the violence of the collision (i.e. impact parameter). (author)

  12. Organic Matter and Barium Absorption by Plant Species Grown in an Area Polluted with Scrap Metal Residue

    Directory of Open Access Journals (Sweden)

    Cleide Aparecida Abreu

    2012-01-01

    Full Text Available The effect of organic matter addition on Ba availability to Helianthus annuus L., Raphanus sativus L., and Ricinus communis L. grown on a Neossolo Litólico Chernossólico fragmentário (pH 7.5, contaminated with scrap residue was evaluated. Four rates (0, 20, 40, and 80 Mg ha−1, organic carbon basis of peat or sugar cane filter, with three replicates, were tested. Plant species were grown until the flowering stage. No effect of organic matter addition to soil on dry matter yield of oilseed radish shoots was observed, but there was an increase in sunflower and castor oil plant shoots when sugar cane filter cake was used. The average Ba transferred from roots to shoots was more than 89% for oilseed radish, 71% for castor oil plants, and 59% for sunflowers. Organic matter treatments were not efficient in reducing Ba availability due to soil liming.

  13. Fragmentation of dimethyl ether in femtosecond intense field

    Science.gov (United States)

    Zhu, Jingyi; Guo, Wei; Wang, Yanqiu; Wang, Li

    2006-08-01

    The fragmentation of dimethyl ether (DME) in intense femtosecond laser field has been studied at 810, 405 and 270 nm with intensities up to 2.48 × 10 15, 3.86 × 10 15 and 1.62 × 10 14 W/cm 2, respectively. At 405 nm, DME is possibly firstly ionized by multiphoton absorption, and then parent ion DME + dissociates into fragments via filed-induced dissociation. For 810 and 270 nm laser fields, DME firstly dissociates into CH 3O and CH 3 fragments and then these neutral fragments are ionized by field tunneling. Another possible way for DME to dissociate at 810 and 270 nm is that DME is ionized by intense field ejection of inner valance electron and then the excited DME + dissociates into fragment ions. Ultrafast rearrangement of DME or DME + in intense field may be responsible to the unpredictable fragment ions, CHO+/C2H5+andH2+.

  14. Fragments of Time

    DEFF Research Database (Denmark)

    Christiansen, Steen Ledet

    Time travel films necessarily fragment linear narratives, as scenes are revisited with differences from the first time we saw it. Popular films such as Back to the Future mine comedy from these visitations, but there are many different approaches. One extreme is Chris Marker's La Jetée - a film...... made almost completely of still images, recounting the end of the world. These stills can be viewed as fragments that have survived the end of the world and now provide the only access to the events that occured. Shane Carruth's Primer has a different approach to time travel, the narrative diegesis...... that is presented; how do we understand such films and to what extent is it even possible to make sense of a film that has no real beginning, middle or end?...

  15. Identifying Interactions that Determine Fragment Binding at Protein Hotspots.

    Science.gov (United States)

    Radoux, Chris J; Olsson, Tjelvar S G; Pitt, Will R; Groom, Colin R; Blundell, Tom L

    2016-05-12

    Locating a ligand-binding site is an important first step in structure-guided drug discovery, but current methods do little to suggest which interactions within a pocket are the most important for binding. Here we illustrate a method that samples atomic hotspots with simple molecular probes to produce fragment hotspot maps. These maps specifically highlight fragment-binding sites and their corresponding pharmacophores. For ligand-bound structures, they provide an intuitive visual guide within the binding site, directing medicinal chemists where to grow the molecule and alerting them to suboptimal interactions within the original hit. The fragment hotspot map calculation is validated using experimental binding positions of 21 fragments and subsequent lead molecules. The ligands are found in high scoring areas of the fragment hotspot maps, with fragment atoms having a median percentage rank of 97%. Protein kinase B and pantothenate synthetase are examined in detail. In each case, the fragment hotspot maps are able to rationalize a Free-Wilson analysis of SAR data from a fragment-based drug design project.

  16. Tooth fragment reattachment techniques-A systematic review.

    Science.gov (United States)

    Garcia, Fernanda Cristina P; Poubel, Déborah L N; Almeida, Júlio César F; Toledo, Isabela P; Poi, Wilson R; Guerra, Eliete N S; Rezende, Liliana V M L

    2018-03-07

    Several strategies have been developed for tooth fragment reattachment following fracture. Although many techniques have been reported, there is no consensus on which one has the best results in terms of the bond strength between the fragment and the dentin over time. The aim of this study was to assess the currently reported tooth fragment reattachment techniques for fractured crowns of anterior teeth. The PubMed, LILACS, Web of Science, Cochrane, and Scopus databases were searched in October 2016, and the search was updated in February 2017. A search of the gray literature was performed in Google Scholar and OpenGrey. Reference lists of eligible studies were cross-checked to identify additional studies; gray literature and ongoing trials were investigated. Two authors assessed studies to determine inclusion and undertook data extraction. Case reports/series of three or more cases, cross-sectional studies, cohort studies, and in vivo clinical trials in all languages were included. Five articles remained after screening. These studies predominantly reported on fragment reattachment with composite resin and resin cement. There was little consistency among the studies in regard to the technique used for tooth fragment reattachment and length of the follow-up period. According to the evidence found in the studies included in this review, simple tooth fragment reattachment was the preferred reattachment technique. An increase in the bond strength between tooth fragment and dentin was observed when an intermediate material was used. Further investigation is needed, using standard follow-up periods and larger samples. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Fragmentation Main Model

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The fragmentation model combines patch size and patch continuity with diversity of vegetation types per patch and rarity of vegetation types per patch. A patch was...

  18. Habitat Fragmentation and Native Bees: a Premature Verdict?

    Directory of Open Access Journals (Sweden)

    James H. Cane

    2001-06-01

    Full Text Available Few studies directly address the consequences of habitat fragmentation for communities of pollinating insects, particularly for the key pollinator group, bees (Hymenoptera: Apiformes. Bees typically live in habitats where nesting substrates and bloom are patchily distributed and spatially dissociated. Bee studies have all defined habitat fragments as remnant patches of floral hosts or forests, overlooking the nesting needs of bees. Several authors conclude that habitat fragmentation is broadly deleterious, but their own data show that some native species proliferate in sampled fragments. Other studies report greater densities and comparable diversities of native bees at flowers in some fragment size classes relative to undisrupted habitats, but find dramatic shifts in species composition. Insightful studies of habitat fragmentation and bees will consider fragmentation, alteration, and loss of nesting habitats, not just patches of forage plants, as well as the permeability of the surrounding matrix to interpatch movement. Inasmuch as the floral associations and nesting habits of bees are often attributes of species or subgenera, ecological interpretations hinge on authoritative identifications. Study designs must accommodate statistical problems associated with bee community samples, especially non-normal data and frequent zero values. The spatial scale of fragmentation must be appreciated: bees of medium body size can regularly fly 1-2 km from nest site to forage patch. Overall, evidence for prolonged persistence of substantial diversity and abundances of native bee communities in habitat fragments of modest size promises practical solutions for maintaining bee populations. Provided that reserve selection, design, and management can address the foraging and nesting needs of bees, networks of even small reserves may hold hope for sustaining considerable pollinator diversity and the ecological services pollinators provide.

  19. Fragmentation Point Detection of JPEG Images at DHT Using Validator

    Science.gov (United States)

    Mohamad, Kamaruddin Malik; Deris, Mustafa Mat

    File carving is an important, practical technique for data recovery in digital forensics investigation and is particularly useful when filesystem metadata is unavailable or damaged. The research on reassembly of JPEG files with RST markers, fragmented within the scan area have been done before. However, fragmentation within Define Huffman Table (DHT) segment is yet to be resolved. This paper analyzes the fragmentation within the DHT area and list out all the fragmentation possibilities. Two main contributions are made in this paper. Firstly, three fragmentation points within DHT area are listed. Secondly, few novel validators are proposed to detect these fragmentations. The result obtained from tests done on manually fragmented JPEG files, showed that all three fragmentation points within DHT are successfully detected using validators.

  20. Dynamical effects in the Colomb expansion following nuclear fragmentation

    International Nuclear Information System (INIS)

    Chung, K.C.; Donangelo, R.J.; Schechter, H.

    1987-01-01

    The effects of the Colomb expansion on the fragment Kinetic energy spectrum for a fragmentating hot nuclear system is investigated. In particular, 12 C fragment spectra are calculated and compared with those predicted by the uniform expansion approximation. The results indicate that energy spectra of fragments are quite sensitive to the details of the Coulomb expansion treatment. (Author) [pt

  1. Bone fragments a body can make

    Energy Technology Data Exchange (ETDEWEB)

    Stout, S.D.; Ross, L.M. Jr. (Department of Anthropology, University of Missouri, Columbia (USA))

    1991-05-01

    Data obtained from various analytical techniques applied to a number of small bone fragments recovered from a crime scene were used to provide evidence for the occurrence of a fatality. Microscopic and histomorphometric analyses confirmed that the fragments were from a human skull. X-ray microanalysis of darkened areas on the bone fragments revealed a chemical signature that matched the chemical signature of a shotgun pellet recovered at the scene of the crime. The above findings supported the deoxyribonucleic acid (DNA) fingerprint evidence which, along with other evidence, was used to convict a man for the murder of his wife, even though her body was never recovered.

  2. HETC-3STEP included fragmentation process

    Energy Technology Data Exchange (ETDEWEB)

    Shigyo, Nobuhiro; Iga, Kiminori; Ishibashi, Kenji [Kyushu Univ., Fukuoka (Japan). Faculty of Engineering

    1997-03-01

    High Energy Transport Code (HETC) based on the cascade-evaporation model is modified to calculate the fragmentation cross section. For the cascade process, nucleon-nucleon cross sections are used for collision computation; effective in-medium-corrected cross sections are adopted instead of the original free-nucleon collision. The exciton model is adopted for improvement of backward nucleon-emission cross section for low-energy nucleon-incident events. The fragmentation reaction is incorporated into the original HETC as a subroutine set by the use of the systematics of the reaction. The modified HETC (HETC-3STEP/FRG) reproduces experimental fragment yields to a reasonable degree. (author)

  3. Integration of fragment screening and library design.

    Science.gov (United States)

    Siegal, Gregg; Ab, Eiso; Schultz, Jan

    2007-12-01

    With more than 10 years of practical experience and theoretical analysis, fragment-based drug discovery (FBDD) has entered the mainstream of the pharmaceutical and biotech industries. An array of biophysical techniques has been used to detect the weak interaction between a fragment and the target. Each technique presents its own requirements regarding the fragment collection and the target; therefore, in order to optimize the potential of FBDD, the nature of the target should be a driving factor for simultaneous development of both the library and the screening technology. A roadmap is now available to guide fragment-to-lead evolution when structural information is available. The next challenge is to apply FBDD to targets for which high-resolution structural information is not available.

  4. Rock fragmentation

    Energy Technology Data Exchange (ETDEWEB)

    Brown, W.S.; Green, S.J.; Hakala, W.W.; Hustrulid, W.A.; Maurer, W.C. (eds.)

    1976-01-01

    Experts in rock mechanics, mining, excavation, drilling, tunneling and use of underground space met to discuss the relative merits of a wide variety of rock fragmentation schemes. Information is presented on novel rock fracturing techniques; tunneling using electron beams, thermocorer, electric spark drills, water jets, and diamond drills; and rock fracturing research needs for mining and underground construction. (LCL)

  5. Light particles emitted with the fission fragments of thorium

    Energy Technology Data Exchange (ETDEWEB)

    San-Tsiang, T; Faraggi, H

    1947-01-01

    The traces produced by the fission of thorium with fast neutrons have been recorded photographically and studied. The formation of a light fragment of long range by either quadripartition or tripartition was not observed. The release of a short-range light fragment by bipartition was observed about one hundred times more frequently than was the release of such a fragment by tripartition. The ratio of the range of the two heavy fragments produced by tripartition was 1:2; this compares with a ratio of 1:3 for the heavy fragments produced by bipartition.

  6. Complex fragment emission from hot compound nuclei

    International Nuclear Information System (INIS)

    Moretto, L.G.

    1986-03-01

    The experimental evidence for compound nucleus emission of complex fragments at low energies is used to interpret the emission of the same fragments at higher energies. The resulting experimental picture is that of highly excited compound nuclei formed in incomplete fusion processes which decay statistically. In particular, complex fragments appear to be produced mostly through compound nucleus decay. In the appendix a geometric-kinematic theory for incomplete fusion and the associated momentum transfer is outlined. 10 refs., 19 figs

  7. Advancement of magma fragmentation by inhomogeneous bubble distribution.

    Science.gov (United States)

    Kameda, M; Ichihara, M; Maruyama, S; Kurokawa, N; Aoki, Y; Okumura, S; Uesugi, K

    2017-12-01

    Decompression times reported in previous studies suggest that thoroughly brittle fragmentation is unlikely in actual explosive volcanic eruptions. What occurs in practice is brittle-like fragmentation, which is defined as the solid-like fracture of a material whose bulk rheological properties are close to those of a fluid. Through laboratory experiments and numerical simulation, the link between the inhomogeneous structure of bubbles and the development of cracks that may lead to brittle-like fragmentation was clearly demonstrated here. A rapid decompression test was conducted to simulate the fragmentation of a specimen whose pore morphology was revealed by X-ray microtomography. The dynamic response during decompression was observed by high-speed photography. Large variation was observed in the responses of the specimens even among specimens with equal bulk rheological properties. The stress fields of the specimens under decompression computed by finite element analysis shows that the presence of satellite bubbles beneath a large bubble induced the stress concentration. On the basis of the obtained results, a new mechanism for brittle-like fragmentation is proposed. In the proposed scenario, the second nucleation of bubbles near the fragmentation surface is an essential process for the advancement of fragmentation in an upward magma flow in a volcanic conduit.

  8. Global-Scale Patterns of Forest Fragmentation

    Directory of Open Access Journals (Sweden)

    Kurt Riitters

    2000-12-01

    Full Text Available We report an analysis of forest fragmentation based on 1-km resolution land-cover maps for the globe. Measurements in analysis windows from 81 km 2 (9 x 9 pixels, "small" scale to 59,049 km 2 (243 x 243 pixels, "large" scale were used to characterize the fragmentation around each forested pixel. We identified six categories of fragmentation (interior, perforated, edge, transitional, patch, and undetermined from the amount of forest and its occurrence as adjacent forest pixels. Interior forest exists only at relatively small scales; at larger scales, forests are dominated by edge and patch conditions. At the smallest scale, there were significant differences in fragmentation among continents; within continents, there were significant differences among individual forest types. Tropical rain forest fragmentation was most severe in North America and least severe in Europe-Asia. Forest types with a high percentage of perforated conditions were mainly in North America (five types and Europe-Asia (four types, in both temperate and subtropical regions. Transitional and patch conditions were most common in 11 forest types, of which only a few would be considered as "naturally patchy" (e.g., dry woodland. The five forest types with the highest percentage of interior conditions were in North America; in decreasing order, they were cool rain forest, coniferous, conifer boreal, cool mixed, and cool broadleaf.

  9. Global-scale patterns of forest fragmentation

    Science.gov (United States)

    Riitters, K.; Wickham, J.; O'Neill, R.; Jones, B.; Smith, E.

    2000-01-01

    We report an analysis of forest fragmentation based on 1-km resolution land-cover maps for the globe. Measurements in analysis windows from 81 km 2 (9 ?? 9 pixels, "small" scale) to 59,049 km 2 (243 ?? 243 pixels, "large" scale) were used to characterize the fragmentation around each forested pixel. We identified six categories of fragmentation (interior, perforated, edge, transitional, patch, and undetermined) from the amount of forest and its occurrence as adjacent forest pixels. Interior forest exists only at relatively small scales; at larger scales, forests are dominated by edge and patch conditions. At the smallest scale, there were significant differences in fragmentation among continents; within continents, there were significant differences among individual forest types. Tropical rain forest fragmentation was most severe in North America and least severe in Europe - Asia. Forest types with a high percentage of perforated conditions were mainly in North America (five types) and Europe - Asia (four types), in both temperate and subtropical regions. Transitional and patch conditions were most common in 11 forest types, of which only a few would be considered as "naturally patchy" (e.g., dry woodland). The five forest types with the highest percentage of interior conditions were in North America; in decreasing order, they were cool rain forest, coniferous, conifer boreal, cool mixed, and cool broadleaf. Copyright ?? 2000 by The Resilience Alliance.

  10. Matter-antimatter and matter-matter interactions at intermediate energies

    International Nuclear Information System (INIS)

    Santos, Antonio Carlos Fontes dos

    2002-01-01

    This article presents some of the recent experimental advances on the study on antimatter-matter and matter-matter interactions, and some of the subtle differences stimulated a great theoretical efforts for explanation of the results experimentally observed

  11. Fragman: an R package for fragment analysis.

    Science.gov (United States)

    Covarrubias-Pazaran, Giovanny; Diaz-Garcia, Luis; Schlautman, Brandon; Salazar, Walter; Zalapa, Juan

    2016-04-21

    Determination of microsatellite lengths or other DNA fragment types is an important initial component of many genetic studies such as mutation detection, linkage and quantitative trait loci (QTL) mapping, genetic diversity, pedigree analysis, and detection of heterozygosity. A handful of commercial and freely available software programs exist for fragment analysis; however, most of them are platform dependent and lack high-throughput applicability. We present the R package Fragman to serve as a freely available and platform independent resource for automatic scoring of DNA fragment lengths diversity panels and biparental populations. The program analyzes DNA fragment lengths generated in Applied Biosystems® (ABI) either manually or automatically by providing panels or bins. The package contains additional tools for converting the allele calls to GenAlEx, JoinMap® and OneMap software formats mainly used for genetic diversity and generating linkage maps in plant and animal populations. Easy plotting functions and multiplexing friendly capabilities are some of the strengths of this R package. Fragment analysis using a unique set of cranberry (Vaccinium macrocarpon) genotypes based on microsatellite markers is used to highlight the capabilities of Fragman. Fragman is a valuable new tool for genetic analysis. The package produces equivalent results to other popular software for fragment analysis while possessing unique advantages and the possibility of automation for high-throughput experiments by exploiting the power of R.

  12. Advances in fragment-based drug discovery platforms.

    Science.gov (United States)

    Orita, Masaya; Warizaya, Masaichi; Amano, Yasushi; Ohno, Kazuki; Niimi, Tatsuya

    2009-11-01

    Fragment-based drug discovery (FBDD) has been established as a powerful alternative and complement to traditional high-throughput screening techniques for identifying drug leads. At present, this technique is widely used among academic groups as well as small biotech and large pharmaceutical companies. In recent years, > 10 new compounds developed with FBDD have entered clinical development, and more and more attention in the drug discovery field is being focused on this technique. Under the FBDD approach, a fragment library of relatively small compounds (molecular mass = 100 - 300 Da) is screened by various methods and the identified fragment hits which normally weakly bind to the target are used as starting points to generate more potent drug leads. Because FBDD is still a relatively new drug discovery technology, further developments and optimizations in screening platforms and fragment exploitation can be expected. This review summarizes recent advances in FBDD platforms and discusses the factors important for the successful application of this technique. Under the FBDD approach, both identifying the starting fragment hit to be developed and generating the drug lead from that starting fragment hit are important. Integration of various techniques, such as computational technology, X-ray crystallography, NMR, surface plasmon resonance, isothermal titration calorimetry, mass spectrometry and high-concentration screening, must be applied in a situation-appropriate manner.

  13. Temperatures of fragment kinetic energy spectra

    International Nuclear Information System (INIS)

    Bauer, W.

    1995-01-01

    Multifragmentation reactions without large compression in the initial state (proton-induced reactions, reverse kinematics, projectile fragmentation) are examined, and it is verified quantitatively that the high temperatures obtained from fragment kinetic energy spectra and lower temperatures obtained from observables such as level population or isotope ratios can be understood in a common framework

  14. The ways and means of fragment-based drug design.

    Science.gov (United States)

    Doak, Bradley C; Norton, Raymond S; Scanlon, Martin J

    2016-11-01

    Fragment-based drug design (FBDD) has emerged as a mainstream approach for the rapid and efficient identification of building blocks that can be used to develop high-affinity ligands against protein targets. One of the strengths of FBDD is the relative ease and low cost of the primary screen to identify fragments that bind. However, the fragments that emerge from primary screens often have low affinities, with K D values in the high μM to mM range, and a significant challenge for FBDD is to develop the initial fragments into more potent ligands. Successful fragment elaboration often requires co-structures of the fragments bound to their target proteins, as well as a range of biophysical and biochemical assays to track potency and efficacy. These challenges have led to the development of specific chemical strategies for the elaboration of weakly-binding fragments into more potent "hits" and lead compounds. In this article we review different approaches that have been employed to meet these challenges and describe some of the strategies that have resulted in several fragment-derived compounds entering clinical trials. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Temporal change in fragmentation of continental US forests

    Science.gov (United States)

    James D. Wickham; Kurt H. Riitters; Timothy G. Wade; Collin Homer

    2008-01-01

    Changes in forest ecosystem function and condition arise from changes in forest fragmentation. Previous studies estimated forest fragmentation for the continental United States (US). In this study, new temporal land-cover data from the National Land Cover Database (NLCD) were used to estimate changes in forest fragmentation at multiple scales for the continental US....

  16. Relationship between Statistical and Dynamical properties of fragments produced at Fermi Energy in Heavy ion collisions: ng; Liens entre les proprietes statistiques et dynamiques des fragments produits lors des collisions d'ions lourds autour de l'energie de Fermi

    Energy Technology Data Exchange (ETDEWEB)

    Lehaut, G.

    2009-10-15

    The properties of the fragments produced in heavy-ion collisions around the Fermi energy have been studied through the isospin degree of freedom. First, a theoretical approach based on a lattice gas model with two types of particles (neutron,proton) interacting by an isospin dependent and Coulomb interactions was developed. The study of the phase diagram shows that this system presents three different phases (liquid, gas, fission). In the liquid and gas phases, the energy of the system was described by a density functional, where the temperature dependence acts only on the density. The symmetry term of this functional was related to the isotopic content of the biggest fragment via an iso-scaling analysis. Secondly a systematic study of the stopping power of the nuclear matter and isospin equilibration of light particles in the most violent collisions was carried out using the experimental data taken by the INDRA multidetector at GANIL and GSI. Two stopping power regimes appear; at low energy (< 40 MeV/A) the stopping power decreases with increasing beam energy, whereas at high energy the stopping power is governed by the quantity of matter along the beam direction. An other study has been focused on the Xe+Sn reaction at 32 and 45 MeV/A with different isospin systems. The separation of three different reaction mechanisms by use of a principal component analysis allowed us to observe that the isospin content of light particles seems to be independent on the mechanism, but depends on the violence of the collision (i.e. impact parameter). (author)

  17. Agricultural matrices affect ground ant assemblage composition inside forest fragments.

    Directory of Open Access Journals (Sweden)

    Diego Santana Assis

    Full Text Available The establishment of agricultural matrices generally involves deforestation, which leads to fragmentation of the remaining forest. This fragmentation can affect forest dynamics both positively and negatively. Since most animal species are affected, certain groups can be used to measure the impact of such fragmentation. This study aimed to measure the impacts of agricultural crops (matrices on ant communities of adjacent lower montane Atlantic rainforest fragments. We sampled nine forest fragments at locations surrounded by different agricultural matrices, namely: coffee (3 replicates; sugarcane (3; and pasture (3. At each site we installed pitfall traps along a 500 m transect from the interior of the matrix to the interior of the fragment (20 pitfall traps ~25 m apart. Each transect was partitioned into four categories: interior of the matrix; edge of the matrix; edge of the fragment; and interior of the fragment. For each sample site, we measured ant species richness and ant community composition within each transect category. Ant richness and composition differed between fragments and matrices. Each sample location had a specific composition of ants, probably because of the influence of the nature and management of the agricultural matrices. Species composition in the coffee matrix had the highest similarity to its corresponding fragment. The variability in species composition within forest fragments surrounded by pasture was greatest when compared with forest fragments surrounded by sugarcane or, to a lesser extent, coffee. Functional guild composition differed between locations, but the most representative guild was 'generalist' both in the agricultural matrices and forest fragments. Our results are important for understanding how agricultural matrices act on ant communities, and also, how these isolated forest fragments could act as an island of biodiversity in an 'ocean of crops'.

  18. Agricultural matrices affect ground ant assemblage composition inside forest fragments.

    Science.gov (United States)

    Assis, Diego Santana; Dos Santos, Iracenir Andrade; Ramos, Flavio Nunes; Barrios-Rojas, Katty Elena; Majer, Jonathan David; Vilela, Evaldo Ferreira

    2018-01-01

    The establishment of agricultural matrices generally involves deforestation, which leads to fragmentation of the remaining forest. This fragmentation can affect forest dynamics both positively and negatively. Since most animal species are affected, certain groups can be used to measure the impact of such fragmentation. This study aimed to measure the impacts of agricultural crops (matrices) on ant communities of adjacent lower montane Atlantic rainforest fragments. We sampled nine forest fragments at locations surrounded by different agricultural matrices, namely: coffee (3 replicates); sugarcane (3); and pasture (3). At each site we installed pitfall traps along a 500 m transect from the interior of the matrix to the interior of the fragment (20 pitfall traps ~25 m apart). Each transect was partitioned into four categories: interior of the matrix; edge of the matrix; edge of the fragment; and interior of the fragment. For each sample site, we measured ant species richness and ant community composition within each transect category. Ant richness and composition differed between fragments and matrices. Each sample location had a specific composition of ants, probably because of the influence of the nature and management of the agricultural matrices. Species composition in the coffee matrix had the highest similarity to its corresponding fragment. The variability in species composition within forest fragments surrounded by pasture was greatest when compared with forest fragments surrounded by sugarcane or, to a lesser extent, coffee. Functional guild composition differed between locations, but the most representative guild was 'generalist' both in the agricultural matrices and forest fragments. Our results are important for understanding how agricultural matrices act on ant communities, and also, how these isolated forest fragments could act as an island of biodiversity in an 'ocean of crops'.

  19. Solving the small-scale structure puzzles with dissipative dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Foot, Robert [ARC Centre of Excellence for Particle Physics at the Terascale, School of Physics, University of Melbourne, Melbourne, Victoria 3010 (Australia); Vagnozzi, Sunny, E-mail: rfoot@unimelb.edu.au, E-mail: sunny.vagnozzi@fysik.su.se [The Oskar Klein Centre for Cosmoparticle Physics, Department of Physics, Stockholm University, AlbaNova University Center, Roslagstullbacken 21A, SE-106 91 Stockholm (Sweden)

    2016-07-01

    Small-scale structure is studied in the context of dissipative dark matter, arising for instance in models with a hidden unbroken Abelian sector, so that dark matter couples to a massless dark photon. The dark sector interacts with ordinary matter via gravity and photon-dark photon kinetic mixing. Mirror dark matter is a theoretically constrained special case where all parameters are fixed except for the kinetic mixing strength, ε. In these models, the dark matter halo around spiral and irregular galaxies takes the form of a dissipative plasma which evolves in response to various heating and cooling processes. It has been argued previously that such dynamics can account for the inferred cored density profiles of galaxies and other related structural features. Here we focus on the apparent deficit of nearby small galaxies (''missing satellite problem'), which these dissipative models have the potential to address through small-scale power suppression by acoustic and diffusion damping. Using a variant of the extended Press-Schechter formalism, we evaluate the halo mass function for the special case of mirror dark matter. Considering a simplified model where M {sub baryons} ∝ M {sub halo}, we relate the halo mass function to more directly observable quantities, and find that for ε ≈ 2 × 10{sup −10} such a simplified description is compatible with the measured galaxy luminosity and velocity functions. On scales M {sub halo} ∼< 10{sup 8} M {sub ⊙}, diffusion damping exponentially suppresses the halo mass function, suggesting a nonprimordial origin for dwarf spheroidal satellite galaxies, which we speculate were formed via a top-down fragmentation process as the result of nonlinear dissipative collapse of larger density perturbations. This could explain the planar orientation of satellite galaxies around Andromeda and the Milky Way.

  20. Solving the small-scale structure puzzles with dissipative dark matter

    Science.gov (United States)

    Foot, Robert; Vagnozzi, Sunny

    2016-07-01

    Small-scale structure is studied in the context of dissipative dark matter, arising for instance in models with a hidden unbroken Abelian sector, so that dark matter couples to a massless dark photon. The dark sector interacts with ordinary matter via gravity and photon-dark photon kinetic mixing. Mirror dark matter is a theoretically constrained special case where all parameters are fixed except for the kinetic mixing strength, epsilon. In these models, the dark matter halo around spiral and irregular galaxies takes the form of a dissipative plasma which evolves in response to various heating and cooling processes. It has been argued previously that such dynamics can account for the inferred cored density profiles of galaxies and other related structural features. Here we focus on the apparent deficit of nearby small galaxies (``missing satellite problem"), which these dissipative models have the potential to address through small-scale power suppression by acoustic and diffusion damping. Using a variant of the extended Press-Schechter formalism, we evaluate the halo mass function for the special case of mirror dark matter. Considering a simplified model where Mbaryons propto Mhalo, we relate the halo mass function to more directly observable quantities, and find that for epsilon ≈ 2 × 10-10 such a simplified description is compatible with the measured galaxy luminosity and velocity functions. On scales Mhalo lesssim 108 Msolar, diffusion damping exponentially suppresses the halo mass function, suggesting a nonprimordial origin for dwarf spheroidal satellite galaxies, which we speculate were formed via a top-down fragmentation process as the result of nonlinear dissipative collapse of larger density perturbations. This could explain the planar orientation of satellite galaxies around Andromeda and the Milky Way.

  1. Multifragmentation of gold nuclei interacting with photoemulsion nuclei at an energy of 10.7 GeV per projectile nucleon

    International Nuclear Information System (INIS)

    Gulamov, K.G.; Navotny, V.Sh.; Uzhinskii, V.V.

    1999-01-01

    Experimental data on the distributions of fragments with respect to the bound charge (Z bound , Z b3 ) and with respect to the multiplicities and on their correlations are presented. These data are compared with analogous data at 600 MeV per projectile nucleon that were obtained at the ALADIN facility. It has been shown that the processes of gold-nucleus multifragmentation at intermediate and high energies have some common features. At the same time, the multiplicity of medium-mass fragments becomes somewhat less at high energies. Data presented in this study are analyzed within the framework combining the statistical model of nuclear multifragmentation with the Regge model of the breakup of nuclei. This combined model has been shown to reproduce qualitatively the experimental results under discussion. The most pronounced discrepancies have been observed for the yields of doubly charged fragments. The transverse momenta of fragments have been analyzed as functions of the bound charge Z bound . It has been demonstrated that the model underestimates considerably the transverse momenta of fragments. This is interpreted as evidence for a strong radial flow of spectator fragments

  2. Fragmentation and structure of silicon microclusters

    International Nuclear Information System (INIS)

    Feuston, B.P.; Kalia, R.K.; Vashishta, P.

    1987-01-01

    It may be possible to determine the magic numbers and fragmentation spectra from the ground-state binding energies and structure, but the relationship between the lowest-energy zero-temperature configurations and the energetics of finite-temperature microclusters is not obvious. Recall fragmentation of Si clusters occurs at temperatures the order of the melting temperature (T∼2000 K). What is needed, a first-principles finite-temperature calculation, allowing the determination of all possible structures, their corresponding binding energies, and fragmentation spectra, is not presently possible. However, a molecular dynamics calculation does allow one to study the nature of fragmentation in addition to determination of the global ground-state structure and all mechanically stable configurations underlying the finite-temperature cluster, once given an interaction potential. The authors present results for such a calculation for Si/sub 2-14/ using the Stillinger-Weber 3-body potential. Their results indicate that the existence of magic numbers is determined by the topology and energetics of high-energy bound structures rather than the structure and ground-state energies at zero temperature

  3. Modelling of the PELE fragmentation dynamics

    Science.gov (United States)

    Verreault, J.

    2014-05-01

    The Penetrator with Enhanced Lateral Effect (PELE) is a type of explosive-free projectile that undergoes radial fragmentation upon an impact with a target plate. This type of projectile is composed of a brittle cylindrical shell (the jacket) filled in its core with a material characterized with a large Poisson's ratio. Upon an impact with a target, the axial compression causes the filling to expand in the radial direction. However, due to the brittleness of the jacket material, very little radial deformation can occur which creates a radial stress between the two materials and a hoop stress in the jacket. Fragmentation of the jacket occurs if the hoop stress exceeds the material's ultimate stress. The PELE fragmentation dynamics is explored via Finite-Element Method (FEM) simulations using the Autodyn explicit dynamics hydrocode. The numerical results are compared with an analytical model based on wave interactions, as well as with the experimental investigation of Paulus and Schirm (1996). The comparison is based on the mechanical stress in the filling and the qualitative fragmentation of the jacket.

  4. Modelling of the PELE fragmentation dynamics

    International Nuclear Information System (INIS)

    Verreault, J

    2014-01-01

    The Penetrator with Enhanced Lateral Effect (PELE) is a type of explosive-free projectile that undergoes radial fragmentation upon an impact with a target plate. This type of projectile is composed of a brittle cylindrical shell (the jacket) filled in its core with a material characterized with a large Poisson's ratio. Upon an impact with a target, the axial compression causes the filling to expand in the radial direction. However, due to the brittleness of the jacket material, very little radial deformation can occur which creates a radial stress between the two materials and a hoop stress in the jacket. Fragmentation of the jacket occurs if the hoop stress exceeds the material's ultimate stress. The PELE fragmentation dynamics is explored via Finite-Element Method (FEM) simulations using the Autodyn explicit dynamics hydrocode. The numerical results are compared with an analytical model based on wave interactions, as well as with the experimental investigation of Paulus and Schirm (1996). The comparison is based on the mechanical stress in the filling and the qualitative fragmentation of the jacket.

  5. Molecular markers. Amplified fragment length polymorphism

    Directory of Open Access Journals (Sweden)

    Pržulj Novo

    2005-01-01

    Full Text Available Amplified Fragment Length Polymorphism molecular markers (AFLPs has been developed combining procedures of RFLPs and RAPDs molekular markers, i.e. the first step is restriction digestion of the genomic DNA that is followed by selective amplification of the restricted fragments. The advantage of the AFLP technique is that it allows rapid generation of a large number of reproducible markers. The reproducibility of AFLPs markers is assured by the use of restriction site-specific adapters and adapter-specific primers for PCR reaction. Only fragments containing the restriction site sequence plus the additional nucleotides will be amplified and the more selected nucleotides added on the primer sequence the fewer the number of fragments amplified by PCR. The amplified products are normally separated on a sequencing gel and visualized after exposure to X-ray film or by using fluorescent labeled primers. AFLP shave proven to be extremely proficient in revealing diversity at below the species level. A disadvantage of AFLP technique is that AFLPs are essentially a dominant marker system and not able to identify heterozygotes.

  6. Hot metastable state of abnormal matter in relativistic nuclear field theory

    International Nuclear Information System (INIS)

    Glendenning, N.K.

    1987-01-01

    Because of their non-linearity, the field equations of relativistic nuclear field theory admit of additional solutions besides the normal state of matter. One of these is a finite-temperature abnormal phase. Over a narrow range in temperature, matter can exist in the abnormal phase at zero pressure. This is a hot metastable state, for which there is a barrier against decay, because the field configuration is different than in the normal state, the baryon masses are far removed from their vacuum masses, there is an abundance of pairs also far removed from their vacuum masses, and a correspondingly high entropy. The abundance of baryon-antibaryon pairs is the glue that holds this matter together. The signals associated with this novel state are quite unusual. A fragment of such matter will cool by emitting a spectrum of black-body radiation, consisting principally of photons, lepton pairs and pions, rather than by baryon emission, because the latter are far removed from their vacuum masses. If produced at the upper end of its temperature range, a large fraction of the original energy, more than half in the examples studied here, is radiated in this way. The baryons and light elements produced in the eventual decay, after the abnormal matter has cooled to a domain where its pressure becomes positive, will account for only a fraction of the original energy. The energy domain of this state depends sensitively on the coupling constants, and within a reasonable range as determined by nuclear matter properties, can lie in the range of GeV to tens of GeV per nucleon. (orig.)

  7. Projectile rapidity dependence in target fragmentation

    International Nuclear Information System (INIS)

    Haustein, P.E.; Cumming, J.B.; Hseuh, H.C.

    1979-01-01

    The thick-target, thick-catcher technique was used to determine mean kinetic properties of selected products of the fragmentation of Cu by 1 H, 4 He, and 12 C ions (180 to 28,000 MeV/amu). Momentum transfer, as inferred from F/B ratios, is ovserved to occur most efficiently for the lower velocity projectiles. Recoil properties of target fragments vary strongly with product mass, but show only a weak dependence on projectile type. The projectile's rapidity is shown to be a useful variable for quantitative intercomparison of different reactions. These results indicate that E/sub proj//A/sub proj/ is the dominant parameter which governs the mean recoil behavior of target fragments. 20 references

  8. The split comets: gravitational interaction between the fragments

    International Nuclear Information System (INIS)

    Sekanina, Z.

    1979-01-01

    The n-body computer program by Schubart and Stumpff (1966) has been slightly modified to study the gravitational interaction between two fragments of a split comet nucleus in the sun's gravitational field. All calculations refer to the orbit of Comet West (1976 VI), the velocity of separation of the fragments is assumed to be equal in magnitude to the velocity of escape from the parent nucleus, and the numerical integration of the relative motion of one fragment (called the companion) with respect to the other (principal fragment) is carried over the period of 200 days from separation. (Auth.)

  9. Surface-Bound Intermediates in Low-Temperature Methanol Synthesis on Copper. Participants and Spectators

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yong; Mei, Donghai; Peden, Charles HF; Campbell, Charles T.; Mims, Charles A.

    2015-11-03

    by titration with pure H2 plus water in sufficient quantities for that intermediate to be observable by IR, formate itself is only a "spectator" in this reaction and gives no observable methanol upon any titration we performed with H2 or H2 plus water.

  10. Compaction of a Bed of Fragmentable Particles and Associated Acoustic Emission

    International Nuclear Information System (INIS)

    Hegron, L.; Sornay, P.; Favretto-Cristini, N.

    2013-06-01

    The nuclear fuel of light water power reactors are manufactured by powder metallurgy. This is also the method that is used for the production of fuels containing minor actinides that have high activity and long life. Given their radiotoxicity, it is necessary to simplify the manufacturing process to the maximum, limiting dissemination and retention of matter. In addition, the fuel must have a mostly open porosity. Implementation of particles of a few hundred micrometers and controlled cohesion could meet this dual objective. However, it should be ensured that the mechanical strength of compacts before sintering is sufficient without adding binder. The phenomena that occur during the manufacture of compact are thus analyzed and quantified. It is shown that only a portion of the particles breaks upon application of a stress up to 600 MPa and it is possible to detect this fragmentation by acoustic emission (AE). (authors)

  11. Momentum sum rules for fragmentation functions

    International Nuclear Information System (INIS)

    Meissner, S.; Metz, A.; Pitonyak, D.

    2010-01-01

    Momentum sum rules for fragmentation functions are considered. In particular, we give a general proof of the Schaefer-Teryaev sum rule for the transverse momentum dependent Collins function. We also argue that corresponding sum rules for related fragmentation functions do not exist. Our model-independent analysis is supplemented by calculations in a simple field-theoretical model.

  12. Translational Entanglement and Teleportation of Matter Wavepackets by Collisions and Half-Collisions

    Science.gov (United States)

    Fisch, L.; Tal, A.; Kurizki, G.

    To date, the translationally-entangled state originally proposed by Einstein, Podolsky and Rosen (EPR) in 1935 has not been experimentally realized for massive particles. Opatrný and Kurizki [Phys. Rev. Lett. 86, 3180 (2000)] have suggested the creation of a position- and momentum-correlated, i.e., translationally-entangled, pair of particles approximating the EPR state by dissociation of cold diatomic molecules, and further manipulation of the EPR pair effecting matter-wave teleportation. Here we aim at setting the principles of and quantifying translational entanglement by collisions and half-collisions. In collisions, the resonance width s and the initial phase-space distributions are shown to determine the degree of post-collisional momentum entanglement. Half-collisions (dissociation) are shown to yield different types of approximate EPR states. We analyse a feasible realization of translational EPR entanglement and teleportation via cold-molecule Raman dissociation and subsequent collisions, resolving both practical and conceptual difficulties it has faced so far: How to avoid entanglement loss due to the wavepacket spreading of the dissociation fragments? How to measure both position and momentum correlations of the dissociation fragments with sufficient accuracy to verify their EPR correlations? How to reliably perform two-particle (Bell) position and momentum measurements on one of the fragments and the wavepacket to be teleported?

  13. Reaction-mechanism evolution for the system 20Ne + 60Ni at intermediate energies: from massive transfer to fragmentation

    International Nuclear Information System (INIS)

    Andreozzi, F.; Brondi, A.; D'Onofrio, A.; LaRana, G.; Moro, R.; Perillo, E.; Romano, M.; Terrasi, F.; Dayras, R.; Dumont, H.; Gadi, F.; Gomez del Campo, J.

    1993-01-01

    Mass and charge distributions for heavy residues in the reaction 20 Ne + 60 Ni at 50 MeV/nucleon were measured by in-beam and off-line γ-ray spectrometry. The stacked foil method was used to obtain information about the distribution of the velocity component parallel to the beam direction for target-like residues. The comparison of the data to the predictions of a participant-spectator model indicates that an 8% width for the dissipated energy distribution accounts for the observed projected ranges. (orig.)

  14. Rock fragmentation control in opencast blasting

    Directory of Open Access Journals (Sweden)

    P.K. Singh

    2016-04-01

    Full Text Available The blasting operation plays a pivotal role in the overall economics of opencast mines. The blasting sub-system affects all the other associated sub-systems, i.e. loading, transport, crushing and milling operations. Fragmentation control through effective blast design and its effect on productivity are the challenging tasks for practicing blasting engineer due to inadequate knowledge of actual explosive energy released in the borehole, varying initiation practice in blast design and its effect on explosive energy release characteristic. This paper describes the result of a systematic study on the impact of blast design parameters on rock fragmentation at three mines in India. The mines use draglines and shovel–dumper combination for removal of overburden. Despite its pivotal role in controlling the overall economics of a mining operation, the expected blasting performance is often judged almost exclusively on the basis of poorly defined parameters such as powder factor and is often qualitative which results in very subjective assessment of blasting performance. Such an approach is very poor substitutes for accurate assessment of explosive and blasting performance. Ninety one blasts were conducted with varying blast designs and charging patterns, and their impacts on the rock fragmentation were documented. A high-speed camera was deployed to record the detonation sequences of the blasts. The efficiency of the loading machines was also correlated with the mean fragment size obtained from the fragmentation analyses.

  15. ACFIS: a web server for fragment-based drug discovery

    Science.gov (United States)

    Hao, Ge-Fei; Jiang, Wen; Ye, Yuan-Nong; Wu, Feng-Xu; Zhu, Xiao-Lei; Guo, Feng-Biao; Yang, Guang-Fu

    2016-01-01

    In order to foster innovation and improve the effectiveness of drug discovery, there is a considerable interest in exploring unknown ‘chemical space’ to identify new bioactive compounds with novel and diverse scaffolds. Hence, fragment-based drug discovery (FBDD) was developed rapidly due to its advanced expansive search for ‘chemical space’, which can lead to a higher hit rate and ligand efficiency (LE). However, computational screening of fragments is always hampered by the promiscuous binding model. In this study, we developed a new web server Auto Core Fragment in silico Screening (ACFIS). It includes three computational modules, PARA_GEN, CORE_GEN and CAND_GEN. ACFIS can generate core fragment structure from the active molecule using fragment deconstruction analysis and perform in silico screening by growing fragments to the junction of core fragment structure. An integrated energy calculation rapidly identifies which fragments fit the binding site of a protein. We constructed a simple interface to enable users to view top-ranking molecules in 2D and the binding mode in 3D for further experimental exploration. This makes the ACFIS a highly valuable tool for drug discovery. The ACFIS web server is free and open to all users at http://chemyang.ccnu.edu.cn/ccb/server/ACFIS/. PMID:27150808

  16. The effective fragment molecular orbital method for fragments connected by covalent bonds.

    Directory of Open Access Journals (Sweden)

    Casper Steinmann

    Full Text Available We extend the effective fragment molecular orbital method (EFMO into treating fragments connected by covalent bonds. The accuracy of EFMO is compared to FMO and conventional ab initio electronic structure methods for polypeptides including proteins. Errors in energy for RHF and MP2 are within 2 kcal/mol for neutral polypeptides and 6 kcal/mol for charged polypeptides similar to FMO but obtained two to five times faster. For proteins, the errors are also within a few kcal/mol of the FMO results. We developed both the RHF and MP2 gradient for EFMO. Compared to ab initio, the EFMO optimized structures had an RMSD of 0.40 and 0.44 Å for RHF and MP2, respectively.

  17. arXiv Generalized Fragmentation Functions for Fractal Jet Observables

    CERN Document Server

    Elder, Benjamin T.; Thaler, Jesse; Waalewijn, Wouter J.; Zhou, Kevin

    2017-06-15

    We introduce a broad class of fractal jet observables that recursively probe the collective properties of hadrons produced in jet fragmentation. To describe these collinear-unsafe observables, we generalize the formalism of fragmentation functions, which are important objects in QCD for calculating cross sections involving identified final-state hadrons. Fragmentation functions are fundamentally nonperturbative, but have a calculable renormalization group evolution. Unlike ordinary fragmentation functions, generalized fragmentation functions exhibit nonlinear evolution, since fractal observables involve correlated subsets of hadrons within a jet. Some special cases of generalized fragmentation functions are reviewed, including jet charge and track functions. We then consider fractal jet observables that are based on hierarchical clustering trees, where the nonlinear evolution equations also exhibit tree-like structure at leading order. We develop a numeric code for performing this evolution and study its phen...

  18. Impact fragmentation of a brittle metal compact

    Science.gov (United States)

    Tang, Megan; Hooper, Joseph P.

    2018-05-01

    The fragmentation behavior of a metal powder compact which is ductile in compression but brittle in tension is studied via impact experiments and analytical models. Consolidated metal compacts were prepared via cold-isostatic pressing of powder at 380 MPa followed by moderate annealing at 365 °C. The resulting zinc material is ductile and strain-hardening in high-rate uniaxial compression like a traditional metal, but is elastic-brittle in tension with a fracture toughness comparable to a ceramic. Cylindrical samples were launched up to 800 m/s in a gas gun into thin aluminum perforation targets, subjecting the projectile to a complex multiaxial and time-dependent stress state that leads to catastrophic fracture. A soft-catch mechanism using low-density artificial snow was developed to recover the impact debris, and collected fragments were analyzed to determine their size distribution down to 30 μm. Though brittle fracture occurs along original particle boundaries, no power-law fragmentation behavior was observed as is seen in other low-toughness materials. An analytical theory is developed to predict the characteristic fragment size accounting for both the sharp onset of fragmentation and the effect of increasing impact velocity.

  19. Supramolecular gel electrophoresis of large DNA fragments.

    Science.gov (United States)

    Tazawa, Shohei; Kobayashi, Kazuhiro; Oyoshi, Takanori; Yamanaka, Masamichi

    2017-10-01

    Pulsed-field gel electrophoresis is a frequent technique used to separate exceptionally large DNA fragments. In a typical continuous field electrophoresis, it is challenging to separate DNA fragments larger than 20 kbp because they migrate at a comparable rate. To overcome this challenge, it is necessary to develop a novel matrix for the electrophoresis. Here, we describe the electrophoresis of large DNA fragments up to 166 kbp using a supramolecular gel matrix and a typical continuous field electrophoresis system. C 3 -symmetric tris-urea self-assembled into a supramolecular hydrogel in tris-boric acid-EDTA buffer, a typical buffer for DNA electrophoresis, and the supramolecular hydrogel was used as a matrix for electrophoresis to separate large DNA fragments. Three types of DNA marker, the λ-Hind III digest (2 to 23 kbp), Lambda DNA-Mono Cut Mix (10 to 49 kbp), and Marker 7 GT (10 to 165 kbp), were analyzed in this study. Large DNA fragments of greater than 100 kbp showed distinct mobility using a typical continuous field electrophoresis system. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. An improved algorithm for MFR fragment assembly

    International Nuclear Information System (INIS)

    Kontaxis, Georg

    2012-01-01

    A method for generating protein backbone models from backbone only NMR data is presented, which is based on molecular fragment replacement (MFR). In a first step, the PDB database is mined for homologous peptide fragments using experimental backbone-only data i.e. backbone chemical shifts (CS) and residual dipolar couplings (RDC). Second, this fragment library is refined against the experimental restraints. Finally, the fragments are assembled into a protein backbone fold using a rigid body docking algorithm using the RDCs as restraints. For improved performance, backbone nuclear Overhauser effects (NOEs) may be included at that stage. Compared to previous implementations of MFR-derived structure determination protocols this model-building algorithm offers improved stability and reliability. Furthermore, relative to CS-ROSETTA based methods, it provides faster performance and straightforward implementation with the option to easily include further types of restraints and additional energy terms.

  1. Contribution to the study of low fragments correlations during Au + Au collisions at 150 and 400 A.MeV; Contribution a l`etude des correlations entre fragments legers dans les collisions Au+Au a 150 et 400 A.MeV

    Energy Technology Data Exchange (ETDEWEB)

    Montbel, I.

    1994-06-01

    The study of fragment-fragment correlations at small relative momenta can give informations on the space-time extend of the emitting source, and on the nuclear density, which is one of the variables used in the equation of state. This analysis shows the experimental results obtained with the FOPI detector at GSI-Darmstadt, for Au + Au central collisions at 150 and 400 A.MeV. These results are the first studies at such high energies and for heavy systems. Two fragments correlation functions are compared with theoretical calculations of D.H. Boal, including the size of the source as a parameter. We must take into account effects of experimental biases (namely the relative momentum resolution) on the theoretical correlation function, in order to make a comparison with experimental results. The extracted experimental radii correspond to the final phase of the expansion, and the obtained densities are smaller that normal density of nuclear matter. In the final state of the interaction, intermediate mass fragments and their excited states are observed. We note a shift of these excited states at 400 A.MeV, which can be explained by the detector effects. We observe a weak sensibility of the source size versus the centrality of the collision. That can be explained either by a mixing of sources, or by the observation of a source at the end of expansion whose the radius is quite independent of the initial centrality. Energetic particles correspond to smaller size of the source, which can be explained as a higher compression, or as a different stage of the collision. We give some prospectives for the future experiments at GSI-Darmstadt. (author). 117 refs.

  2. Novel fragmentation model for pulverized coal particles gasification in low temperature air thermal plasma

    Directory of Open Access Journals (Sweden)

    Jovanović Rastko D.

    2016-01-01

    Full Text Available New system for start-up and flame support based on coal gasification by low temperature air thermal plasma is planned to supplement current heavy oil system in Serbian thermal power plants in order to decrease air pollutions emission and operational costs. Locally introduced plasma thermal energy heats up and ignites entrained coal particles, thus starting chain process which releases heat energy from gasified coal particles inside burner channel. Important stages during particle combustion, such as particle devolatilisation and char combustion, are described with satisfying accuracy in existing commercial CFD codes that are extensively used as powerful tool for pulverized coal combustion and gasification modeling. However, during plasma coal gasification, high plasma temperature induces strong thermal stresses inside interacting coal particles. These stresses lead to “thermal shock” and extensive particle fragmentation during which coal particles with initial size of 50-100 m disintegrate into fragments of at most 5-10 m. This intensifies volatile release by a factor 3-4 and substantially accelerates the oxidation of combustible matter. Particle fragmentation, due to its small size and thus limited influence on combustion process is commonly neglected in modelling. The main focus of this work is to suggest novel approach to pulverized coal gasification under high temperature conditions and to implement it into commercial comprehensive code ANSYS FLUENT 14.0. Proposed model was validated against experimental data obtained in newly built pilot scale D.C plasma burner test facility. Newly developed model showed very good agreement with experimental results with relative error less than 10%, while the standard built-in gasification model had error up to 25%.

  3. Extracellular matrix fragmentation in young, healthy cartilaginous tissues.

    Science.gov (United States)

    Craddock, R J; Hodson, N W; Ozols, M; Shearer, T; Hoyland, J A; Sherratt, M J

    2018-02-09

    Although the composition and structure of cartilaginous tissues is complex, collagen II fibrils and aggrecan are the most abundant assemblies in both articular cartilage (AC) and the nucleus pulposus (NP) of the intervertebral disc (IVD). Whilst structural heterogeneity of intact aggrecan ( containing three globular domains) is well characterised, the extent of aggrecan fragmentation in healthy tissues is poorly defined. Using young, yet skeletally mature (18-30 months), bovine AC and NP tissues, it was shown that, whilst the ultrastructure of intact aggrecan was tissue-dependent, most molecules (AC: 95 %; NP: 99.5 %) were fragmented (lacking one or more globular domains). Fragments were significantly smaller and more structurally heterogeneous in the NP compared with the AC (molecular area; AC: 8543 nm2; NP: 4625 nm2; p tissue-invariant. Molecular fragmentation is considered indicative of a pathology; however, these young, skeletally mature tissues were histologically and mechanically (reduced modulus: AC: ≈ 500 kPa; NP: ≈ 80 kPa) comparable to healthy tissues and devoid of notable gelatinase activity (compared with rat dermis). As aggrecan fragmentation was prevalent in neonatal bovine AC (99.5 % fragmented, molecular area: 5137 nm2) as compared with mature AC (95.0 % fragmented, molecular area: 8667 nm2), it was hypothesised that targeted proteolysis might be an adaptive process that modified aggrecan packing (as simulated computationally) and, hence, tissue charge density, mechanical properties and porosity. These observations provided a baseline against which pathological and/or age-related fragmentation of aggrecan could be assessed and suggested that new strategies might be required to engineer constructs that mimic the mechanical properties of native cartilaginous tissues.

  4. Modelling the fragmentation mechanisms

    International Nuclear Information System (INIS)

    Bougault, R.; Durand, D.; Gulminelli, F.

    1998-01-01

    We have investigated the role of high amplitude collective motion in the nuclear fragmentation by using semi-classical macroscopic, as well as, microscopic simulations (BUU). These studies are motivated by the search of instabilities responsible for nuclear fragmentation. Two cases were examined: the bubble formation following the collective expansion of the compressed nucleus in case of very central reactions and, in the case of the semi-central collisions, the fast fission of the two partners issued from a binary reaction, in their corresponding Coulomb field. In the two cases the fragmentation channel is dominated by the inter-relation between the Coulomb and nuclear fields, and it is possible to obtain semi-quantitative predictions as functions of interaction parameters. The transport equations of BUU type predicts for central reactions formation of a high density transient state. Of much interest is the mechanism subsequent to de-excitation. It seems reasonable to conceive that the pressure stocked in the compressional mode manifests itself as a collective expansion of the system. As the pressure is a increasing function of the available energy one can conceive a variety of energy depending exit channels, starting from the fragmentation due the amplification of fluctuations interior to the spinodal zone up to the complete vaporization of the highly excited system. If the reached pressure is sufficiently high the reaction final state may preserve the memory of the entrance channel as a collective radial energy superimposed to the thermal disordered motion. Distributions of particles in the configuration space for both central and semi-central reactions for the Pb+Au system are presented. The rupture time is estimated to the order of 300 fm/c, and is strongly dependent on the initial temperature. The study of dependence of the rupture time on the interaction parameters is under way

  5. Limestone fragmentation and attrition during fluidized bed oxyfiring

    Energy Technology Data Exchange (ETDEWEB)

    Fabrizio Scala; Piero Salatino [Istituto di Ricerche sulla Combustione - CNR, Napoli (Italy)

    2010-04-15

    Attrition/fragmentation of limestone under simulated fluidized bed oxyfiring conditions was investigated by means of an experimental protocol that had been previously developed for characterization of attrition/fragmentation of sorbents in air-blown atmospheric fluidized bed combustors. The protocol was based on the use of different and mutually complementary techniques. The extent and pattern of attrition by surface wear in the dense phase of a fluidized bed were assessed in experiments carried out with a bench scale fluidized bed combustor under simulated oxyfiring conditions. Sorbent samples generated during simulated oxyfiring tests were further characterized from the standpoint of fragmentation upon high velocity impact by means of a purposely designed particle impactor. Results showed that under calcination-hindered conditions attrition and fragmentation patterns are much different from those occurring under air-blown atmospheric combustion conditions. Noteworthy, attrition/fragmentation enhanced particle sulfation by continuously regenerating the exposed particle surface. 13 refs., 8 figs.

  6. Residue preference mapping of ligand fragments in the Protein Data Bank.

    Science.gov (United States)

    Wang, Lirong; Xie, Zhaojun; Wipf, Peter; Xie, Xiang-Qun

    2011-04-25

    The interaction between small molecules and proteins is one of the major concerns for structure-based drug design because the principles of protein-ligand interactions and molecular recognition are not thoroughly understood. Fortunately, the analysis of protein-ligand complexes in the Protein Data Bank (PDB) enables unprecedented possibilities for new insights. Herein, we applied molecule-fragmentation algorithms to split the ligands extracted from PDB crystal structures into small fragments. Subsequently, we have developed a ligand fragment and residue preference mapping (LigFrag-RPM) algorithm to map the profiles of the interactions between these fragments and the 20 proteinogenic amino acid residues. A total of 4032 fragments were generated from 71 798 PDB ligands by a ring cleavage (RC) algorithm. Among these ligand fragments, 315 unique fragments were characterized with the corresponding fragment-residue interaction profiles by counting residues close to these fragments. The interaction profiles revealed that these fragments have specific preferences for certain types of residues. The applications of these interaction profiles were also explored and evaluated in case studies, showing great potential for the study of protein-ligand interactions and drug design. Our studies demonstrated that the fragment-residue interaction profiles generated from the PDB ligand fragments can be used to detect whether these fragments are in their favorable or unfavorable environments. The algorithm for a ligand fragment and residue preference mapping (LigFrag-RPM) developed here also has the potential to guide lead chemistry modifications as well as binding residues predictions.

  7. Fragmentation of Continental United States Forests

    Science.gov (United States)

    Kurt H. Riitters; James D. Wickham; Robert V. O' Neill; K. Bruce Jones; Elizabeth R. Smith; John W. Coulston; Timothy G. Wade; Jonathan H. Smith

    2002-01-01

    We report a multiple-scale analysis of forest fragmentation based on 30-m (0.09 ha pixel-1) land- cover maps for the conterminous United States. Each 0.09-ha unit of forest was classified according to fragmentation indexes measured within the surrounding landscape, for five landscape sizes including 2.25, 7.29, 65.61, 590.49, and 5314.41 ha....

  8. High efficiency hydrodynamic DNA fragmentation in a bubbling system

    NARCIS (Netherlands)

    Li, Lanhui; Jin, Mingliang; Sun, Chenglong; Wang, Xiaoxue; Xie, Shuting; Zhou, Guofu; Van Den Berg, Albert; Eijkel, Jan C.T.; Shui, Lingling

    2017-01-01

    DNA fragmentation down to a precise fragment size is important for biomedical applications, disease determination, gene therapy and shotgun sequencing. In this work, a cheap, easy to operate and high efficiency DNA fragmentation method is demonstrated based on hydrodynamic shearing in a bubbling

  9. PELE fragmentation dynamics

    NARCIS (Netherlands)

    Verreault, J.; Hinsberg, N.P. van; Abadjieva, E.

    2013-01-01

    An analytical model that describes the PELE fragmentation dynamics is presented and compared with experimental results from literature. The model accounts for strong shock effects and detailed interactions taking place between the filling – the inner core of the ammunition – and the target

  10. Fragmented Work Stories

    DEFF Research Database (Denmark)

    Humle, Didde Maria; Reff Pedersen, Anne

    2015-01-01

    stories. We argue that meaning by story making is not always created by coherence and causality; meaning is created by different types of fragmentation: discontinuities, tensions and editing. The objective of this article is to develop and advance antenarrative practice analysis of work stories...

  11. Collision induced fragmentation dynamics of small metallic clusters; Dynamique de fragmentation induite par collision de petits agregats metalliques

    Energy Technology Data Exchange (ETDEWEB)

    Picard, Y

    1999-04-15

    The goal of this work is the complete analysis of the fragmentation of alkali clusters (Na{sub n}{sup +} (n < 10), NaK{sup +} and K{sub 2}{sup +}) induced by collision with light atomic (He) or molecular (H{sub 2}) targets. The main point is to study how the energy is transmitted to the cluster during the collision and how this energy is shared among the various degrees of freedom of the system and leads to its fragmentation. Two types of interactions govern the collision induced dissociation processes: on one hand, the electronic mechanisms where the target perturbs the electronic cloud and brings the molecule into a dissociative state, and on the other hand, the impulsive mechanisms where the momentum transferred to the atomic cores leads to the rotational-vibrational dissociation of the molecule. The experimental procedure is based on the measurement of the velocity vectors of the outgoing fragments detected in coincidence. This allows to reconstruct the full kinematics of the fragmentation and to separate and characterize for the first time the two types of interactions. The two basic mechanisms of collision induced dissociation are then clearly resolved for the diatomic molecule Na{sub 2}{sup +}. For the heteronuclear molecular ion NaK{sup +}, it is shown that the dissociation process is due to a combination of electronic and impulsive mechanisms in some of the dissociation pathways. The extension to the study of metallic clusters Na{sub n}{sup +} (n < 10) fragmentation shows the role and the relative importance of the electronic and impulsive mechanisms and their evolution with the cluster size. The complete analysis of Na{sub 3}{sup +} multi-fragmentation is also presented. (author)

  12. Microbial platform technology for recombinant antibody fragment production: A review.

    Science.gov (United States)

    Gupta, Sanjeev Kumar; Shukla, Pratyoosh

    2017-02-01

    Recombinant antibody fragments are being used for the last few years as an important therapeutic protein to cure various critical and life threatening human diseases. Several expression platforms now days employed for the production of these recombinant fragments, out of which bacterial system has emerged a promising host for higher expression. Since, a small antibody fragment unlike full antibody does not require human-like post-translational modification therefore it is potentially expressed in prokaryotic production system. Recently, small antibody fragments such as scFvs (single-chain variable fragments) and Fabs (antibody fragments) which does not require glycosylation are successfully produced in bacteria and have commercially launched for therapeutic use as these fragments shows better tissue penetration and less immunogenic to human body compared to full-size antibody. Recently developed Wacker's ESETEC secretion technology is an efficient technology for the expression and secretion of the antibody fragment (Fab) exceeded up to 4.0 g/L while scFv up to 3.5 g/L into the fermentation broth. The Pfenex system and pOP prokaryotic expression vector are another platform used for the considerably good amount of antibody fragment production successfully. In this review, we summarize the recent progress on various expression platforms and cloning approaches for the production of different forms of antibody fragments in E. coli.

  13. A fragment separator at LBL for beta-NMR experiment

    International Nuclear Information System (INIS)

    Matsuta, K.; Ozawa, A.; Nojiri, Y.; Minamisono, T.; Fukuda, M.; Kitagawa, A.; Ohtsubo, T.; Momota, S.; Fukuda, S.; Matsuo, Y.; Takechi, H.; Minami, I.; Sugimoto, K.; Tanihata, I.; Omata, K.; Alonso, J.R.; Krebs, G.F.; Symons, T.J.M.

    1992-03-01

    The Beam 44 fragment separator was built at the Bevalac of LBL for NMR studies of beta emitting nuclei. 37 K, 39 Ca, and 43 Ti fragments originating from 40 Ca and 46 Ti primary beams were separated by the separator for NMR studies on these nuclei. Nuclear spin polarization was created in 39 Ca and 43 Ti using the tilted foil technique (TFT), and the magnetic moment of 43 Ti was deduced. Fragment polarization was measured for 37 K and 39 Ca emitted to finite deflection angles. The Beam 44 fragment separator in combination with a proper polarization technique, such as TFT or fragment polarization, has been very effective for such NMR studies

  14. Pollen and gene flow in fragmented habitats

    NARCIS (Netherlands)

    Kwak, Manja M.; Velterop, Odilia; van Andel, Jelte

    . Habitat fragmentation affects both plants and pollinators. Habitat fragmentation leads to changes in species richness, population number and size, density, and shape, thus to changes in the spatial arrangement of flowers. These changes influence the amount of food for flower-visiting insects and

  15. ACFIS: a web server for fragment-based drug discovery.

    Science.gov (United States)

    Hao, Ge-Fei; Jiang, Wen; Ye, Yuan-Nong; Wu, Feng-Xu; Zhu, Xiao-Lei; Guo, Feng-Biao; Yang, Guang-Fu

    2016-07-08

    In order to foster innovation and improve the effectiveness of drug discovery, there is a considerable interest in exploring unknown 'chemical space' to identify new bioactive compounds with novel and diverse scaffolds. Hence, fragment-based drug discovery (FBDD) was developed rapidly due to its advanced expansive search for 'chemical space', which can lead to a higher hit rate and ligand efficiency (LE). However, computational screening of fragments is always hampered by the promiscuous binding model. In this study, we developed a new web server Auto Core Fragment in silico Screening (ACFIS). It includes three computational modules, PARA_GEN, CORE_GEN and CAND_GEN. ACFIS can generate core fragment structure from the active molecule using fragment deconstruction analysis and perform in silico screening by growing fragments to the junction of core fragment structure. An integrated energy calculation rapidly identifies which fragments fit the binding site of a protein. We constructed a simple interface to enable users to view top-ranking molecules in 2D and the binding mode in 3D for further experimental exploration. This makes the ACFIS a highly valuable tool for drug discovery. The ACFIS web server is free and open to all users at http://chemyang.ccnu.edu.cn/ccb/server/ACFIS/. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  16. Searching Fragment Spaces with feature trees.

    Science.gov (United States)

    Lessel, Uta; Wellenzohn, Bernd; Lilienthal, Markus; Claussen, Holger

    2009-02-01

    Virtual combinatorial chemistry easily produces billions of compounds, for which conventional virtual screening cannot be performed even with the fastest methods available. An efficient solution for such a scenario is the generation of Fragment Spaces, which encode huge numbers of virtual compounds by their fragments/reagents and rules of how to combine them. Similarity-based searches can be performed in such spaces without ever fully enumerating all virtual products. Here we describe the generation of a huge Fragment Space encoding about 5 * 10(11) compounds based on established in-house synthesis protocols for combinatorial libraries, i.e., we encode practically evaluated combinatorial chemistry protocols in a machine readable form, rendering them accessible to in silico search methods. We show how such searches in this Fragment Space can be integrated as a first step in an overall workflow. It reduces the extremely huge number of virtual products by several orders of magnitude so that the resulting list of molecules becomes more manageable for further more elaborated and time-consuming analysis steps. Results of a case study are presented and discussed, which lead to some general conclusions for an efficient expansion of the chemical space to be screened in pharmaceutical companies.

  17. Laser-assisted shape selective fragmentation of nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Kazakevich, P.V. [Wave Research Center, General Physics Institute of the Russian Academy of Sciences, 38, Vavilov street, 117942 Moscow (Russian Federation); Simakin, A.V. [Wave Research Center, General Physics Institute of the Russian Academy of Sciences, 38, Vavilov street, 117942 Moscow (Russian Federation); Shafeev, G.A. [Wave Research Center, General Physics Institute of the Russian Academy of Sciences, 38, Vavilov street, 117942 Moscow (Russian Federation)]. E-mail: shafeev@kapella.gpi.ru; Viau, G. [ITODYS, UMR 7086, Universite Paris 7-Denis Diderot, case 7090, 2 place Jussieu, 75251 Paris Cedex 05 (France); Soumare, Y. [ITODYS, UMR 7086, Universite Paris 7-Denis Diderot, case 7090, 2 place Jussieu, 75251 Paris Cedex 05 (France); Bozon-Verduraz, F. [ITODYS, UMR 7086, Universite Paris 7-Denis Diderot, case 7090, 2 place Jussieu, 75251 Paris Cedex 05 (France)

    2007-07-31

    Experimental results are presented on laser-assisted fragmentation of gold-containing nanoparticles suspended in liquids (either ethanol or water). Two kinds of nanoparticles are considered: (i) elongated Au nanorods synthesized by laser ablation of a gold target immersed in liquid phase; (ii) gold-covered NiCo nanorods with high aspect ratio ({theta} {approx} 10) synthesized by wet chemistry processes. The shape selectivity induced by laser fragmentation of these nanorods is gained via tuning the wavelength of laser radiation into different parts of the spectrum of their plasmon resonance corresponding to different aspect ratios {theta}. Fragmentation is performed using three laser wavelengths, involving a Cu vapour laser (510 and 578 nm) and a Nd:YAG (1064 nm). Nanoparticles are characterized by UV-vis spectrometry, Transmission Electron Microscopy (TEM). The effect of laser pulse duration (nanosecond against picosecond range) is also studied in the case of fragmentation with an IR laser radiation.

  18. NJL-jet model for quark fragmentation functions

    International Nuclear Information System (INIS)

    Ito, T.; Bentz, W.; Cloeet, I. C.; Thomas, A. W.; Yazaki, K.

    2009-01-01

    A description of fragmentation functions which satisfy the momentum and isospin sum rules is presented in an effective quark theory. Concentrating on the pion fragmentation function, we first explain why the elementary (lowest order) fragmentation process q→qπ is completely inadequate to describe the empirical data, although the crossed process π→qq describes the quark distribution functions in the pion reasonably well. Taking into account cascadelike processes in a generalized jet-model approach, we then show that the momentum and isospin sum rules can be satisfied naturally, without the introduction of ad hoc parameters. We present results for the Nambu-Jona-Lasinio (NJL) model in the invariant mass regularization scheme and compare them with the empirical parametrizations. We argue that the NJL-jet model, developed herein, provides a useful framework with which to calculate the fragmentation functions in an effective chiral quark theory.

  19. Fragment screening by SPR and advanced application to GPCRs.

    Science.gov (United States)

    Shepherd, Claire A; Hopkins, Andrew L; Navratilova, Iva

    2014-01-01

    Surface plasmon resonance (SPR) is one of the primary biophysical methods for the screening of low molecular weight 'fragment' libraries, due to its low protein consumption and 'label-free' methodology. SPR biosensor interaction analysis is employed to both screen and confirm the binding of compounds in fragment screening experiments, as it provides accurate information on the affinity and kinetics of molecular interactions. The most advanced application of the use of SPR for fragment screening is against membrane protein drug targets, such G-protein coupled receptors (GPCRs). Biophysical GPCR assays using SPR have been validated with pharmacological measurements approximate to cell-based methods, yet provide the advantage of biophysical methods in their ability to measure the weak affinities of low molecular weight fragments. A number of SPR fragment screens against GPCRs have now been disclosed in the literature. SPR fragment screening is proving versatile to screen both thermostabilised GPCRs and solubilised wild type receptors. In this chapter, we discuss the state-of-the-art in GPCR fragment screening by SPR and the technical considerations in performing such experiments. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  20. Clustering document fragments using background color and texture information

    Science.gov (United States)

    Chanda, Sukalpa; Franke, Katrin; Pal, Umapada

    2012-01-01

    Forensic analysis of questioned documents sometimes can be extensively data intensive. A forensic expert might need to analyze a heap of document fragments and in such cases to ensure reliability he/she should focus only on relevant evidences hidden in those document fragments. Relevant document retrieval needs finding of similar document fragments. One notion of obtaining such similar documents could be by using document fragment's physical characteristics like color, texture, etc. In this article we propose an automatic scheme to retrieve similar document fragments based on visual appearance of document paper and texture. Multispectral color characteristics using biologically inspired color differentiation techniques are implemented here. This is done by projecting document color characteristics to Lab color space. Gabor filter-based texture analysis is used to identify document texture. It is desired that document fragments from same source will have similar color and texture. For clustering similar document fragments of our test dataset we use a Self Organizing Map (SOM) of dimension 5×5, where the document color and texture information are used as features. We obtained an encouraging accuracy of 97.17% from 1063 test images.

  1. Observation for really cold fragmentation of heavy nucleus

    International Nuclear Information System (INIS)

    Goverdovskij, A.A.; Ketlerov, V.V.; Mitrofanov, V.F.; Ostapenko, Yu.B.; Khryachkov, V.A.

    1998-01-01

    The results of the detailed study on mass-energy charged correlations of the thorium-232 fission fragments, produced by the 5 MeV neutrons are presented. The event of the thorium nucleus really cold fragmentation into tellurium-134 and strontium-99 at the basic quantum states is identified. It is shown that the whole reaction energy is exhausted by the motion kinetic energy of the fragments in the mutual field

  2. Extracellular matrix fragmentation in young, healthy cartilaginous tissues

    Directory of Open Access Journals (Sweden)

    RJ Craddock

    2018-02-01

    Full Text Available Although the composition and structure of cartilaginous tissues is complex, collagen II fibrils and aggrecan are the most abundant assemblies in both articular cartilage (AC and the nucleus pulposus (NP of the intervertebral disc (IVD. Whilst structural heterogeneity of intact aggrecan ( containing three globular domains is well characterised, the extent of aggrecan fragmentation in healthy tissues is poorly defined. Using young, yet skeletally mature (18-30 months, bovine AC and NP tissues, it was shown that, whilst the ultrastructure of intact aggrecan was tissue-dependent, most molecules (AC: 95 %; NP: 99.5 % were fragmented (lacking one or more globular domains. Fragments were significantly smaller and more structurally heterogeneous in the NP compared with the AC (molecular area; AC: 8543 nm2; NP: 4625 nm2; p < 0.0001. In contrast, fibrillar collagen appeared structurally intact and tissue-invariant. Molecular fragmentation is considered indicative of a pathology; however, these young, skeletally mature tissues were histologically and mechanically (reduced modulus: AC: ≈ 500 kPa; NP: ≈ 80 kPa comparable to healthy tissues and devoid of notable gelatinase activity (compared with rat dermis. As aggrecan fragmentation was prevalent in neonatal bovine AC (99.5 % fragmented, molecular area: 5137 nm2 as compared with mature AC (95.0 % fragmented, molecular area: 8667 nm2, it was hypothesised that targeted proteolysis might be an adaptive process that modified aggrecan packing (as simulated computationally and, hence, tissue charge density, mechanical properties and porosity. These observations provided a baseline against which pathological and/or age-related fragmentation of aggrecan could be assessed and suggested that new strategies might be required to engineer constructs that mimic the mechanical properties of native cartilaginous tissues.

  3. FRAGSION: ultra-fast protein fragment library generation by IOHMM sampling.

    Science.gov (United States)

    Bhattacharya, Debswapna; Adhikari, Badri; Li, Jilong; Cheng, Jianlin

    2016-07-01

    Speed, accuracy and robustness of building protein fragment library have important implications in de novo protein structure prediction since fragment-based methods are one of the most successful approaches in template-free modeling (FM). Majority of the existing fragment detection methods rely on database-driven search strategies to identify candidate fragments, which are inherently time-consuming and often hinder the possibility to locate longer fragments due to the limited sizes of databases. Also, it is difficult to alleviate the effect of noisy sequence-based predicted features such as secondary structures on the quality of fragment. Here, we present FRAGSION, a database-free method to efficiently generate protein fragment library by sampling from an Input-Output Hidden Markov Model. FRAGSION offers some unique features compared to existing approaches in that it (i) is lightning-fast, consuming only few seconds of CPU time to generate fragment library for a protein of typical length (300 residues); (ii) can generate dynamic-size fragments of any length (even for the whole protein sequence) and (iii) offers ways to handle noise in predicted secondary structure during fragment sampling. On a FM dataset from the most recent Critical Assessment of Structure Prediction, we demonstrate that FGRAGSION provides advantages over the state-of-the-art fragment picking protocol of ROSETTA suite by speeding up computation by several orders of magnitude while achieving comparable performance in fragment quality. Source code and executable versions of FRAGSION for Linux and MacOS is freely available to non-commercial users at http://sysbio.rnet.missouri.edu/FRAGSION/ It is bundled with a manual and example data. chengji@missouri.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  4. Quantifying Urban Fragmentation under Economic Transition in Shanghai City, China

    Directory of Open Access Journals (Sweden)

    Heyuan You

    2015-12-01

    Full Text Available Urban fragmentation affects sustainability through multiple impacts on economic, social, and environmental cost. Characterizing the dynamics of urban fragmentation in relation to economic transition should provide implications for sustainability. However, rather few efforts have been made in this issue. Using the case of Shanghai (China, this paper quantifies urban fragmentation in relation to economic transition. In particular, urban fragmentation is quantified by a time-series of remotely sensed images and a set of landscape metrics; and economic transition is described by a set of indicators from three aspects (globalization, decentralization, and marketization. Results show that urban fragmentation presents an increasing linear trend. Multivariate regression identifies positive linear correlation between urban fragmentation and economic transition. More specifically, the relative influence is different for the three components of economic transition. The relative influence of decentralization is stronger than that of globalization and marketization. The joint influences of decentralization and globalization are the strongest for urban fragmentation. The demonstrated methodology can be applicable to other places after making suitable adjustment of the economic transition indicators and fragmentation metrics.

  5. Refolding Technologies for Antibody Fragments

    Directory of Open Access Journals (Sweden)

    Tsutomu Arakawa

    2014-05-01

    Full Text Available Refolding is one of the production technologies for pharmaceutical grade antibody fragments. Detergents and denaturants are primarily used to solubilize the insoluble proteins. The solubilized and denatured proteins are refolded by reducing the concentration of the denaturants or detergents. Several refolding technologies have been used for antibody fragments, comprising dilution, dialysis, solid phase solvent exchange and size exclusion chromatography, as reviewed here. Aggregation suppressor or folding-assisting agents, including arginine hydrochloride, ionic liquids and detergents or denaturants at low concentrations, are included in the refolding solvent to enhance refolding yield.

  6. Binding-site assessment by virtual fragment screening.

    Directory of Open Access Journals (Sweden)

    Niu Huang

    2010-04-01

    Full Text Available The accurate prediction of protein druggability (propensity to bind high-affinity drug-like small molecules would greatly benefit the fields of chemical genomics and drug discovery. We have developed a novel approach to quantitatively assess protein druggability by computationally screening a fragment-like compound library. In analogy to NMR-based fragment screening, we dock approximately 11,000 fragments against a given binding site and compute a computational hit rate based on the fraction of molecules that exceed an empirically chosen score cutoff. We perform a large-scale evaluation of the approach on four datasets, totaling 152 binding sites. We demonstrate that computed hit rates correlate with hit rates measured experimentally in a previously published NMR-based screening method. Secondly, we show that the in silico fragment screening method can be used to distinguish known druggable and non-druggable targets, including both enzymes and protein-protein interaction sites. Finally, we explore the sensitivity of the results to different receptor conformations, including flexible protein-protein interaction sites. Besides its original aim to assess druggability of different protein targets, this method could be used to identifying druggable conformations of flexible binding site for lead discovery, and suggesting strategies for growing or joining initial fragment hits to obtain more potent inhibitors.

  7. Universal Rim Thickness in Unsteady Sheet Fragmentation

    Science.gov (United States)

    Wang, Y.; Dandekar, R.; Bustos, N.; Poulain, S.; Bourouiba, L.

    2018-05-01

    Unsteady fragmentation of a fluid bulk into droplets is important for epidemiology as it governs the transport of pathogens from sneezes and coughs, or from contaminated crops in agriculture. It is also ubiquitous in industrial processes such as paint, coating, and combustion. Unsteady fragmentation is distinct from steady fragmentation on which most theoretical efforts have been focused thus far. We address this gap by studying a canonical unsteady fragmentation process: the breakup from a drop impact on a finite surface where the drop fluid is transferred to a free expanding sheet of time-varying properties and bounded by a rim of time-varying thickness. The continuous rim destabilization selects the final spray droplets, yet this process remains poorly understood. We combine theory with advanced image analysis to study the unsteady rim destabilization. We show that, at all times, the rim thickness is governed by a local instantaneous Bond number equal to unity, defined with the instantaneous, local, unsteady rim acceleration. This criterion is found to be robust and universal for a family of unsteady inviscid fluid sheet fragmentation phenomena, from impacts of drops on various surface geometries to impacts on films. We discuss under which viscous and viscoelastic conditions the criterion continues to govern the unsteady rim thickness.

  8. Oral lead bullet fragment exposure in northern bobwhite (Colinus virginianus).

    Science.gov (United States)

    Kerr, Richard; Holladay, Jeremy; Holladay, Steven; Tannenbaum, Lawrence; Selcer, Barbara; Meldrum, Blair; Williams, Susan; Jarrett, Timothy; Gogal, Robert

    2011-11-01

    Lead (Pb) is a worldwide environmental contaminant known to adversely affect multiple organ systems in both mammalian and avian species. In birds, a common route of exposure is via oral ingestion of lead particles. Data are currently lacking for the retention and clearance of Pb bullet fragments in gastrointestinal (GI) tract of birds while linking toxicity with blood Pb levels. In the present study, northern bobwhite quail fed a seed-based diet were orally gavaged with Pb bullet fragments (zero, one or five fragments/bird) and evaluated for rate of fragment clearance, and changes in peripheral blood, renal, immune, and gastrointestinal parameters. Based on radiographs, the majority of the birds cleared or absorbed the fragments by seven days, with the exception of one five-fragment bird which took between 7 and 14 days. Blood Pb levels were higher in males than females, which may be related to egg production in females. In males but not females, feed consumption, body weight gain, packed cell volume (PCV), plasma protein concentration, and δ-aminolevulinic acid dehydratase (δ-ALAD) activity were all adversely affected by five Pb fragments. Birds of both sexes that received a single Pb fragment displayed depressed δ-ALAD, suggesting altered hematologic function, while all birds dosed with five bullet fragments exhibited greater morbidity.

  9. Meta-analysis of the effects of forest fragmentation on interspecific interactions.

    Science.gov (United States)

    Magrach, Ainhoa; Laurance, William F; Larrinaga, Asier R; Santamaria, Luis

    2014-10-01

    Forest fragmentation dramatically alters species persistence and distribution and affects many ecological interactions among species. Recent studies suggest that mutualisms, such as pollination and seed dispersal, are more sensitive to the negative effects of forest fragmentation than antagonisms, such as predation or herbivory. We applied meta-analytical techniques to evaluate this hypothesis and quantified the relative contributions of different components of the fragmentation process (decreases in fragment size, edge effects, increased isolation, and habitat degradation) to the overall effect. The effects of fragmentation on mutualisms were primarily driven by habitat degradation, edge effects, and fragment isolation, and, as predicted, they were consistently more negative on mutualisms than on antagonisms. For the most studied interaction type, seed dispersal, only certain components of fragmentation had significant (edge effects) or marginally significant (fragment size) effects. Seed size modulated the effect of fragmentation: species with large seeds showed stronger negative impacts of fragmentation via reduced dispersal rates. Our results reveal that different components of the habitat fragmentation process have varying impacts on key mutualisms. We also conclude that antagonistic interactions have been understudied in fragmented landscapes, most of the research has concentrated on particular types of mutualistic interactions such as seed dispersal, and that available studies of interspecific interactions have a strong geographical bias (arising mostly from studies carried out in Brazil, Chile, and the United States). © 2014 Society for Conservation Biology.

  10. Scission configurations and their implication in fission-fragment angular momenta

    International Nuclear Information System (INIS)

    Bonneau, L.; Quentin, P.; Mikhailov, I. N.

    2007-01-01

    The generation of sizable angular momenta in fragments formed in low-energy nuclear fission is described microscopically within the general quantum-mechanical framework of orientation pumping due to the Heisenberg uncertainty principle. Within this framework, we make use of the results of Skyrme-Hartree-Fock plus BCS-pairing calculations of fragment deformabilities to deduce a distribution of fission-fragment spins as a function of the fragment total excitation energy. We consider a fragmentation corresponding to a pair of deformed fragments and for which fission data are available. The properties of the scission configurations determine to a large extent the fission-fragment spins. This is why we pay particular attention to quantitatively defining the scission configurations and to studying the various implications of such a specific choice. A fair qualitative agreement with data is demonstrated and discussed within the limits of the simple scission-configuration model used here

  11. Recombinant Kinase Production and Fragment Screening by NMR Spectroscopy.

    Science.gov (United States)

    Han, Byeonggu; Ahn, Hee-Chul

    2016-01-01

    During the past decade fragment-based drug discovery (FBDD) has rapidly evolved and several drugs or drug candidates developed by FBDD approach are clinically in use or in clinical trials. For example, vemurafenib, a V600E mutated BRAF inhibitor, was developed by utilizing FBDD approach and approved by FDA in 2011. In FBDD, screening of fragments is the starting step for identification of hits and lead generation. Fragment screening usually relies on biophysical techniques by which the protein-bound small molecules can be detected. NMR spectroscopy has been extensively used to study the molecular interaction between the protein and the ligand, and has many advantages in fragment screening over other biophysical techniques. This chapter describes the practical aspects of fragment screening by saturation transfer difference NMR.

  12. Evolution of fragment-fragment correlations in reactions of 197Au and 107,109Ag with 40Ar from 7A to 34A MeV

    International Nuclear Information System (INIS)

    Ethvignot, T.; Ajitanand, N.N.; Alexander, J.M.; Bauge, E.; Elmaani, A.; Kowalski, L.; Lopez, M.; Magda, M.T.; Desesquelles, P.; Elhage, H.; Giorni, A.; Heuer, D.; Kox, S.; Lleres, A.; Merchez, F.; Morand, C.; Rebreyend, D.; Stassi, P.; Viano, J.B.; Benrachi, F.; Chambon, B.; Cheynis, B.; Drain, D.; Pastor, C.

    1992-01-01

    In-plane and out-of-plane angular correlations have been measured between fragments of Z>3, Li fragments, 3,4 He, and 1,2,3 H. The changing patterns for 40 Ar induced reactions of 7A, 17A, 27A, and 34A MeV give an overview of the decreasing importance of mass-symmetric fissionlike reactions at the expense of a broad range of more mass-asymmetric breakups. Evidence is given that these fragments come from a central collision group of reactions that have similar violence and from which many combinations of fragments and particles are ejected. Very similar azimuthal angular correlations are observed for particles with a Li fragment and for particles with a pair of heavier fragments (Z>3). This similarity suggests comparable strengths of association with the reaction plane for single Li fragments and for fragment pairs of Z>3. Azimuthal angular correlations for Li-Li pairs exhibit distinct asymmetries; their interpretation via trajectory-model calculations indicates mean delay times of ∼5x10 -22 s

  13. Modified dark matter: Relating dark energy, dark matter and baryonic matter

    Science.gov (United States)

    Edmonds, Douglas; Farrah, Duncan; Minic, Djordje; Ng, Y. Jack; Takeuchi, Tatsu

    Modified dark matter (MDM) is a phenomenological model of dark matter, inspired by gravitational thermodynamics. For an accelerating universe with positive cosmological constant (Λ), such phenomenological considerations lead to the emergence of a critical acceleration parameter related to Λ. Such a critical acceleration is an effective phenomenological manifestation of MDM, and it is found in correlations between dark matter and baryonic matter in galaxy rotation curves. The resulting MDM mass profiles, which are sensitive to Λ, are consistent with observational data at both the galactic and cluster scales. In particular, the same critical acceleration appears both in the galactic and cluster data fits based on MDM. Furthermore, using some robust qualitative arguments, MDM appears to work well on cosmological scales, even though quantitative studies are still lacking. Finally, we comment on certain nonlocal aspects of the quanta of modified dark matter, which may lead to novel nonparticle phenomenology and which may explain why, so far, dark matter detection experiments have failed to detect dark matter particles.

  14. Resilient networks of ant-plant mutualists in Amazonian forest fragments.

    Science.gov (United States)

    Passmore, Heather A; Bruna, Emilio M; Heredia, Sylvia M; Vasconcelos, Heraldo L

    2012-01-01

    The organization of networks of interacting species, such as plants and animals engaged in mutualisms, strongly influences the ecology and evolution of partner communities. Habitat fragmentation is a globally pervasive form of spatial heterogeneity that could profoundly impact the structure of mutualist networks. This is particularly true for biodiversity-rich tropical ecosystems, where the majority of plant species depend on mutualisms with animals and it is thought that changes in the structure of mutualist networks could lead to cascades of extinctions. We evaluated effects of fragmentation on mutualistic networks by calculating metrics of network structure for ant-plant networks in continuous Amazonian forests with those in forest fragments. We hypothesized that networks in fragments would have fewer species and higher connectance, but equal nestedness and resilience compared to forest networks. Only one of the nine metrics we compared differed between continuous forest and forest fragments, indicating that networks were resistant to the biotic and abiotic changes that accompany fragmentation. This is partially the result of the loss of only specialist species with one connection that were lost in forest fragments. We found that the networks of ant-plant mutualists in twenty-five year old fragments are similar to those in continuous forest, suggesting these interactions are resistant to the detrimental changes associated with habitat fragmentation, at least in landscapes that are a mosaic of fragments, regenerating forests, and pastures. However, ant-plant mutualistic networks may have several properties that may promote their persistence in fragmented landscapes. Proactive identification of key mutualist partners may be necessary to focus conservation efforts on the interactions that insure the integrity of network structure and the ecosystems services networks provide.

  15. Resilient networks of ant-plant mutualists in Amazonian forest fragments.

    Directory of Open Access Journals (Sweden)

    Heather A Passmore

    Full Text Available The organization of networks of interacting species, such as plants and animals engaged in mutualisms, strongly influences the ecology and evolution of partner communities. Habitat fragmentation is a globally pervasive form of spatial heterogeneity that could profoundly impact the structure of mutualist networks. This is particularly true for biodiversity-rich tropical ecosystems, where the majority of plant species depend on mutualisms with animals and it is thought that changes in the structure of mutualist networks could lead to cascades of extinctions.We evaluated effects of fragmentation on mutualistic networks by calculating metrics of network structure for ant-plant networks in continuous Amazonian forests with those in forest fragments. We hypothesized that networks in fragments would have fewer species and higher connectance, but equal nestedness and resilience compared to forest networks. Only one of the nine metrics we compared differed between continuous forest and forest fragments, indicating that networks were resistant to the biotic and abiotic changes that accompany fragmentation. This is partially the result of the loss of only specialist species with one connection that were lost in forest fragments.We found that the networks of ant-plant mutualists in twenty-five year old fragments are similar to those in continuous forest, suggesting these interactions are resistant to the detrimental changes associated with habitat fragmentation, at least in landscapes that are a mosaic of fragments, regenerating forests, and pastures. However, ant-plant mutualistic networks may have several properties that may promote their persistence in fragmented landscapes. Proactive identification of key mutualist partners may be necessary to focus conservation efforts on the interactions that insure the integrity of network structure and the ecosystems services networks provide.

  16. Absolute fragmentation cross sections in atom-molecule collisions : Scaling laws for non-statistical fragmentation of polycyclic aromatic hydrocarbon molecules

    NARCIS (Netherlands)

    Chen, T.; Gatchell, M.; Stockett, M. H.; Alexander, J. D.; Zhang, Y.; Rousseau, P.; Domaracka, A.; Maclot, S.; Delaunay, R.; Adoui, L.; Huber, B. A.; Schlathölter, T.; Schmidt, H. T.; Cederquist, H.; Zettergren, H.

    2014-01-01

    We present scaling laws for absolute cross sections for non-statistical fragmentation in collisions between Polycyclic Aromatic Hydrocarbons (PAH/PAH+) and hydrogen or helium atoms with kinetic energies ranging from 50 eV to 10 keV. Further, we calculate the total fragmentation cross sections

  17. Sub-fragmentation of structural-reactive-material casings under explosion

    Science.gov (United States)

    Zhang, Fan

    2015-06-01

    The sub-fragmentation of structural reactive material (SRM) thick-casings is to generate fine fragments during casing fragmentation under explosive loading for their efficient energy release to enhance air blast. This has been investigated using a cylindrical casing made from either rich Al-MoO3 or Al-W-based granular composites. The former composite was to study the concept of reactive hot spots where the reaction of reactive particles, which were distributed into base SRM in a fuel-rich equivalence ratio, created heat and gas products during SRM fragmentation. The expansion of these distributed hot spots initiated local fractures of the casing, leading to fine fragments. The Al-W-based composite investigated the concept of impedance mismatch, where shock dynamics at the interfaces of different impedance ingredients resulted in non-uniform, high local temperatures and stresses and late in times the dissimilar inertia resulted in different accelerations, leading to material separation and fine fragments. The casings were manufactured through both hot iso-static pressing and cold gas dynamic spray deposition. Explosion experiments were conducted in a 3 m diameter, 23 m3 cylindrical chamber for these cased charges in a casing-to-explosive mass ratio of 1.75. The results demonstrated the presence of fine fragments and more efficient fragment combustion, compared with previous results, and indicated the effectiveness of both concepts. This work was jointly funded by Defence R&D Canada and the Advanced Energetics Program of DTRA (Dr. William H. Wilson).

  18. Simulation of natural fragmentation of rings cut from warheads

    Directory of Open Access Journals (Sweden)

    John F. Moxnes

    2015-12-01

    Full Text Available Natural fragmentation of warheads that detonates causes the casing of the warhead to split into various sized fragments through shear or radial fractures depending on the toughness, density, and grain size of the material. The best known formula for the prediction of the size distribution is the Mott formulae, which is further examined by Grady and Kipp by investigating more carefully the statistical most random way of portioning a given area into a number of entities. We examine the fragmentation behavior of radially expanding steel rings cut from a 25 mm warhead by using an in house smooth particle hydrodynamic (SPH simulation code called REGULUS. Experimental results were compared with numerical results applying varying particle size and stochastic fracture strain. The numerically obtained number of fragments was consistent with experimental results. Increasing expansion velocity of the rings increases the number of fragments. Statistical variation of the material parameters influences the fragment characteristics, especially for low expansion velocities. A least square regression fit to the cumulative number of fragments by applying a generalized Mott distribution shows that the shape parameter is around 4 for the rings, which is in contrast to the Mott distribution with a shape parameter of ½. For initially polar distributed particles, we see signs of a bimodal cumulative fragment distribution. Adding statistical variation in material parameters of the fracture model causes the velocity numerical solutions to become less sensitive to changes in resolution for Cartesian distributed particles.

  19. Studies of complex fragment emission in heavy ion reactions

    International Nuclear Information System (INIS)

    Sobotka, L.G.

    1989-01-01

    The production of large fragments, fragments with mass between light particles and fission fragments, in intermediate and high energy nuclear reactions has fostered the proposal of a number of novel reaction mechanisms. These include liquid-vapor equilibrium and nuclear shattering. Temporarily left in the wake of these exciting proposed mechanisms was the old standard, statistical decay of compound nuclei. To be sure, the standard treatment of compound nucleus decay did not deal with large fragment production. However, this omission was not due to any fundamental deficiency of statistical models, but rather an uncertainty concerning exactly how to splice large fragment emission into statistical models. A large portion of our program deals with this problem. Specifically, by studying the yields of large fragments produced in sufficiently low energy reactions we are attempting to deduce the asymmetry and l-wave dependence of large fragment emission from compound nuclear intermediates. This, however, is only half of the problem. Since the novel mechanisms proposed for large fragment emission were spawned by intermediate and high energy reaction data, we must also realize the relevance of the compound nucleus mechanisms at high energies. It is not unreasonable to suspect that compound nucleus-like objects are formed with less than complete momentum transfer and perhaps less than complete mass transfer. Therefore the study of energy, mass, and angular momentum transfer in incomplete fusion and non-compound reactions. This thread joins the apparently divergent subjects covered in this report

  20. The Role of Nuclear Fragmentation in Particle Therapy and Space Radiation Protection

    Directory of Open Access Journals (Sweden)

    Cary eZeitlin

    2016-03-01

    Full Text Available The transport of so-called HZE particles (those having high charge, Z, and energy, E through matter is crucially important both in space radiation protection and in the clinical setting where heavy ions are used for cancer treatment. Transport physics is governed by two types of interactions, electromagnetic (ionization energy loss and nuclear. Models of transport such as those used in treatment planning and space mission planning must account for both effects in detail. The theory of electromagnetic interactions is well developed, but nucleus-nucleus collisions are so complex that no fundamental physical theory currently describes them. Instead, interaction models are generally anchored to experimental data, which in some areas are far from complete. The lack of fundamental physics knowledge introduces uncertainties in the calculations of exposures and their associated risks. These uncertainties are greatly compounded by the much larger uncertainties in biological response to HZE particles. In this article, we discuss the role of nucleus-nucleus interactions in heavy charged particle therapy and in deep space, where astronauts will receive a chronic low dose from Galactic Cosmic Rays (GCRs and potentially higher short-term doses from sporadic, unpredictable Solar Energetic Particles (SEPs. GCRs include HZE particles; SEPs typically do not and we therefore exclude them from consideration in this article. Nucleus-nucleus collisions can result in the breakup of heavy ions into lighter ions. In space, this is generally beneficial because dose and dose equivalent are, on the whole, reduced in the process. The GCRs can be considered a radiation field with a significant high-LET component; when they pass through matter, the high-LET component is attenuated, at the cost of a slight increase in the low-LET component. Not only are the standard measures of risk reduced by fragmentation, but it can be argued that fragmentation also reduces the