WorldWideScience

Sample records for space conditioning costs

  1. Improving the thermal integrity of new single-family detached residential buildings: Documentation for a regional database of capital costs and space conditioning load savings

    International Nuclear Information System (INIS)

    Koomey, J.G.; McMahon, J.E.; Wodley, C.

    1991-07-01

    This report summarizes the costs and space-conditioning load savings from improving new single-family building shells. It relies on survey data from the National Association of Home-builders (NAHB) to assess current insulation practices for these new buildings, and NAHB cost data (aggregated to the Federal region level) to estimate the costs of improving new single-family buildings beyond current practice. Space-conditioning load savings are estimated using a database of loads for prototype buildings developed at Lawrence Berkeley Laboratory, adjusted to reflect population-weighted average weather in each of the ten federal regions and for the nation as a whole

  2. Space Station Freedom operations costs

    Science.gov (United States)

    Accola, Anne L.; Williams, Gregory J.

    1988-01-01

    Measures to reduce the operation costs of the Space Station which can be implemented in the design and development stages are discussed. Operational functions are described in the context of an overall operations concept. The provisions for operations cost responsibilities among the partners in the Space Station program are presented. Cost estimating methodologies and the way in which operations costs affect the design and development process are examined.

  3. Cost Modeling for Space Telescope

    Science.gov (United States)

    Stahl, H. Philip

    2011-01-01

    Parametric cost models are an important tool for planning missions, compare concepts and justify technology investments. This paper presents on-going efforts to develop single variable and multi-variable cost models for space telescope optical telescope assembly (OTA). These models are based on data collected from historical space telescope missions. Standard statistical methods are used to derive CERs for OTA cost versus aperture diameter and mass. The results are compared with previously published models.

  4. Parametric Cost Models for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd; Dollinger, Courtney

    2010-01-01

    Multivariable parametric cost models for space telescopes provide several benefits to designers and space system project managers. They identify major architectural cost drivers and allow high-level design trades. They enable cost-benefit analysis for technology development investment. And, they provide a basis for estimating total project cost. A survey of historical models found that there is no definitive space telescope cost model. In fact, published models vary greatly [1]. Thus, there is a need for parametric space telescopes cost models. An effort is underway to develop single variable [2] and multi-variable [3] parametric space telescope cost models based on the latest available data and applying rigorous analytical techniques. Specific cost estimating relationships (CERs) have been developed which show that aperture diameter is the primary cost driver for large space telescopes; technology development as a function of time reduces cost at the rate of 50% per 17 years; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and increasing mass reduces cost.

  5. Parametric cost models for space telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd; Dollinger, Courtnay

    2017-11-01

    Multivariable parametric cost models for space telescopes provide several benefits to designers and space system project managers. They identify major architectural cost drivers and allow high-level design trades. They enable cost-benefit analysis for technology development investment. And, they provide a basis for estimating total project cost. A survey of historical models found that there is no definitive space telescope cost model. In fact, published models vary greatly [1]. Thus, there is a need for parametric space telescopes cost models. An effort is underway to develop single variable [2] and multi-variable [3] parametric space telescope cost models based on the latest available data and applying rigorous analytical techniques. Specific cost estimating relationships (CERs) have been developed which show that aperture diameter is the primary cost driver for large space telescopes; technology development as a function of time reduces cost at the rate of 50% per 17 years; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and increasing mass reduces cost.

  6. Preliminary Multivariable Cost Model for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip

    2010-01-01

    Parametric cost models are routinely used to plan missions, compare concepts and justify technology investments. Previously, the authors published two single variable cost models based on 19 flight missions. The current paper presents the development of a multi-variable space telescopes cost model. The validity of previously published models are tested. Cost estimating relationships which are and are not significant cost drivers are identified. And, interrelationships between variables are explored

  7. Preliminary Cost Model for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Prince, F. Andrew; Smart, Christian; Stephens, Kyle; Henrichs, Todd

    2009-01-01

    Parametric cost models are routinely used to plan missions, compare concepts and justify technology investments. However, great care is required. Some space telescope cost models, such as those based only on mass, lack sufficient detail to support such analysis and may lead to inaccurate conclusions. Similarly, using ground based telescope models which include the dome cost will also lead to inaccurate conclusions. This paper reviews current and historical models. Then, based on data from 22 different NASA space telescopes, this paper tests those models and presents preliminary analysis of single and multi-variable space telescope cost models.

  8. Cost-estimating relationships for space programs

    Science.gov (United States)

    Mandell, Humboldt C., Jr.

    1992-01-01

    Cost-estimating relationships (CERs) are defined and discussed as they relate to the estimation of theoretical costs for space programs. The paper primarily addresses CERs based on analogous relationships between physical and performance parameters to estimate future costs. Analytical estimation principles are reviewed examining the sources of errors in cost models, and the use of CERs is shown to be affected by organizational culture. Two paradigms for cost estimation are set forth: (1) the Rand paradigm for single-culture single-system methods; and (2) the Price paradigms that incorporate a set of cultural variables. For space programs that are potentially subject to even small cultural changes, the Price paradigms are argued to be more effective. The derivation and use of accurate CERs is important for developing effective cost models to analyze the potential of a given space program.

  9. Top Level Space Cost Methodology (TLSCM)

    Science.gov (United States)

    1997-12-02

    Software 7 6. ACEIT . 7 C. Ground Rules and Assumptions 7 D. Typical Life Cycle Cost Distribution 7 E. Methodologies 7 1. Cost/budget Threshold 9 2. Analogy...which is based on real-time Air Force and space programs. Ref.(25:2- 8, 2-9) 6. ACEIT : Automated Cost Estimating Integrated Tools( ACEIT ), Tecolote...Research, Inc. There is a way to use the ACEIT cost program to get a print-out of an expanded WBS. Therefore, find someone that has ACEIT experience and

  10. Parametric cost estimation for space science missions

    Science.gov (United States)

    Lillie, Charles F.; Thompson, Bruce E.

    2008-07-01

    Cost estimation for space science missions is critically important in budgeting for successful missions. The process requires consideration of a number of parameters, where many of the values are only known to a limited accuracy. The results of cost estimation are not perfect, but must be calculated and compared with the estimates that the government uses for budgeting purposes. Uncertainties in the input parameters result from evolving requirements for missions that are typically the "first of a kind" with "state-of-the-art" instruments and new spacecraft and payload technologies that make it difficult to base estimates on the cost histories of previous missions. Even the cost of heritage avionics is uncertain due to parts obsolescence and the resulting redesign work. Through experience and use of industry best practices developed in participation with the Aerospace Industries Association (AIA), Northrop Grumman has developed a parametric modeling approach that can provide a reasonably accurate cost range and most probable cost for future space missions. During the initial mission phases, the approach uses mass- and powerbased cost estimating relationships (CER)'s developed with historical data from previous missions. In later mission phases, when the mission requirements are better defined, these estimates are updated with vendor's bids and "bottoms- up", "grass-roots" material and labor cost estimates based on detailed schedules and assigned tasks. In this paper we describe how we develop our CER's for parametric cost estimation and how they can be applied to estimate the costs for future space science missions like those presented to the Astronomy & Astrophysics Decadal Survey Study Committees.

  11. Optimizing grade-control drillhole spacing with conditional simulations

    Directory of Open Access Journals (Sweden)

    Adrian Martínez-Vargas

    2017-01-01

    Full Text Available This paper summarizes a method to determine the optimum spacing of grade-control drillholes drilled with reverse-circulation. The optimum drillhole spacing was defined as that one whose cost equals the cost of misclassifying ore and waste in selection mining units (SMU. The cost of misclassification of a given drillhole spacing is equal to the cost of processing waste misclassified as ore (Type I error plus the value of the ore misclassified as waste (Type II error. Type I and Type II errors were deduced by comparing true and estimated grades at SMUs, in relation to a cuttoff grade value and assuming free ore selection. True grades at SMUs and grades at drillhole samples were generated with conditional simulations. A set of estimated grades at SMU, one per each drillhole spacing, were generated with ordinary kriging. This method was used to determine the optimum drillhole spacing in a gold deposit. The results showed that the cost of misclassification is sensitive to extreme block values and tend to be overrepresented. Capping SMU’s lost values and implementing diggability constraints was recommended to improve calculations of total misclassification costs.

  12. Space construction system analysis. Part 2: Cost and programmatics

    Science.gov (United States)

    Vonflue, F. W.; Cooper, W.

    1980-01-01

    Cost and programmatic elements of the space construction systems analysis study are discussed. The programmatic aspects of the ETVP program define a comprehensive plan for the development of a space platform, the construction system, and the space shuttle operations/logistics requirements. The cost analysis identified significant items of cost on ETVP development, ground, and flight segments, and detailed the items of space construction equipment and operations.

  13. The Space Medicine Exploration Medical Condition List

    Science.gov (United States)

    Watkins, Sharmi; Barr, Yael; Kerstman, Eric

    2011-01-01

    Exploration Medical Capability (ExMC) is an element of NASA s Human Research Program (HRP). ExMC's goal is to address the risk of the "Inability to Adequately Recognize or Treat an Ill or Injured Crewmember." This poster highlights the approach ExMC has taken to address this risk. The Space Medicine Exploration Medical Condition List (SMEMCL) was created to define the set of medical conditions that are most likely to occur during exploration space flight missions. The list was derived from the International Space Station Medical Checklist, the Shuttle Medical Checklist, in-flight occurrence data from the Lifetime Surveillance of Astronaut Health, and NASA subject matter experts. The list of conditions was further prioritized for eight specific design reference missions with the assistance of the ExMC Advisory Group. The purpose of the SMEMCL is to serve as an evidence-based foundation for the conditions that could affect a crewmember during flight. This information is used to ensure that the appropriate medical capabilities are available for exploration missions.

  14. Atomic collisions under extreme conditions in space

    International Nuclear Information System (INIS)

    Itikawa, Yukikazu

    1987-01-01

    In space, atoms and molecules are often placed under the extreme conditions which are very difficult to be realized on Earth. For instance, extremely hot and dense plasmas are found in and around various stellar objects (e.g., neutron stars) on one hand and extremely cold and diffuse gases prevail in interstellar space on the other. There is so strong a magnetic field that electron clouds in atoms and molecules are distorted. The study of atomic collisions under the extreme conditions is not only helpful in understanding the astrophysical environment but also reveals new aspects of the physics of atoms and molecules. This paper is an invitation to the study. (References are not exhaustive but only provide a clue with which more details can be found.) (author)

  15. Power conditioning for space nuclear reactor systems

    Science.gov (United States)

    Berman, Baruch

    1987-01-01

    This paper addresses the power conditioning subsystem for both Stirling and Brayton conversion of space nuclear reactor systems. Included are the requirements summary, trade results related to subsystem implementation, subsystem description, voltage level versus weight, efficiency and operational integrity, components selection, and shielding considerations. The discussion is supported by pertinent circuit and block diagrams. Summary conclusions and recommendations derived from the above studies are included.

  16. OPEN SPACE ALLOCATION AND TRAVEL COSTS

    OpenAIRE

    Kovacs, Kent F.

    2003-01-01

    The gain from dividing parks into smaller pieces to reduce travel costs is weighed against the loss in services the parks provide since they are smaller. The optimal number of parks is dependent on whether travel costs are concentrated in parts of the town.

  17. The cost of poor working conditions

    NARCIS (Netherlands)

    Koningsveld, E.A.P.; Houtman, I.L.D.

    2004-01-01

    An estimate of the multiple costs incurred by workplace accidents, illnesses and long-term absence puts the amount at 3% of total GNP in the Netherlands. Musculoskeletal disorders and psychosocial diseases are responsible for 83% of the cost of work-related health issues.

  18. Estimating the costs of human space exploration

    Science.gov (United States)

    Mandell, Humboldt C., Jr.

    1994-01-01

    The plan for NASA's new exploration initiative has the following strategic themes: (1) incremental, logical evolutionary development; (2) economic viability; and (3) excellence in management. The cost estimation process is involved with all of these themes and they are completely dependent upon the engineering cost estimator for success. The purpose is to articulate the issues associated with beginning this major new government initiative, to show how NASA intends to resolve them, and finally to demonstrate the vital importance of a leadership role by the cost estimation community.

  19. Volumes of conditioned bipartite state spaces

    International Nuclear Information System (INIS)

    Milz, Simon; Strunz, Walter T

    2015-01-01

    We analyze the metric properties of conditioned quantum state spaces M η (n×m) . These spaces are the convex sets of nm×nm density matrices that, when partially traced over m degrees of freedom, respectively yield the given n × n density matrix η. For the case n = 2, the volume of M η (2×m) equipped with the Hilbert–Schmidt measure can be conjectured to be a simple polynomial of the radius of η in the Bloch-ball. Remarkably, for m=2,3 we find numerically that the probability p sep (2×m) (η) to find a separable state in M η (2×m) is independent of η (except for η pure). For m>3, the same holds for p PosPart (2×m) (η), the probability to find a state with a positive partial transpose in M η (2×m) . These results are proven analytically for the case of the family of 4 × 4 X-states, and thoroughly numerically investigated for the general case. The important implications of these findings for the clarification of open problems in quantum theory are pointed out and discussed. (paper)

  20. The Mackey convergence condition for spaces with webs

    Directory of Open Access Journals (Sweden)

    Thomas E. Gilsdorf

    1988-01-01

    Full Text Available If each sequence converging to 0 in a locally convex space is also Mackey convergent to 0, that space is said to satisfy the Mackey convergence condition. The problem of characterizing those locally convex spaces with this property is still open. In this paper, spaces with compatible webs are used to construct both a necessary and a sufficient condition for a locally convex space to satisfy the Mackey convergence condition.

  1. Preliminary Multi-Variable Cost Model for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Hendrichs, Todd

    2010-01-01

    Parametric cost models are routinely used to plan missions, compare concepts and justify technology investments. This paper reviews the methodology used to develop space telescope cost models; summarizes recently published single variable models; and presents preliminary results for two and three variable cost models. Some of the findings are that increasing mass reduces cost; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and technology development as a function of time reduces cost at the rate of 50% per 17 years.

  2. Low-Load Space Conditioning Needs Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Puttagunta, Srikanth [Consortium for Advanced Residential Buildings (CARB), Norwalk, CT (United States)

    2015-05-19

    Heating, ventilating, and air-conditioning (HVAC) equipment must be right-sized to ensure energy performance and comfort. With limited low-load options in the HVAC market, many new-construction housing units are being fitted with oversized equipment that creates system efficiency, comfort, and cost penalties. To bridge the gap between currently available HVAC equipment that is oversized or inefficient and the rising demand for low-load HVAC equipment in the marketplace, HVAC equipment manufacturers need to be fully aware of the needs of the multifamily building and attached single-family (duplex and townhouse) home market. Over the past decade, Steven Winter Associates, Inc. (SWA) has provided certification and consulting services for hundreds of housing projects and has accrued a large pool of data that describe multifamily and attached single-family home characteristics. The U.S. Department of Energy’s Building America research team Consortium for Advanced Residential Buildings (CARB) compiled and analyzed these data to outline the characteristics of low-load dwellings such as the heating and cooling design loads.

  3. SOFTCOST - DEEP SPACE NETWORK SOFTWARE COST MODEL

    Science.gov (United States)

    Tausworthe, R. C.

    1994-01-01

    The early-on estimation of required resources and a schedule for the development and maintenance of software is usually the least precise aspect of the software life cycle. However, it is desirable to make some sort of an orderly and rational attempt at estimation in order to plan and organize an implementation effort. The Software Cost Estimation Model program, SOFTCOST, was developed to provide a consistent automated resource and schedule model which is more formalized than the often used guesswork model based on experience, intuition, and luck. SOFTCOST was developed after the evaluation of a number of existing cost estimation programs indicated that there was a need for a cost estimation program with a wide range of application and adaptability to diverse kinds of software. SOFTCOST combines several software cost models found in the open literature into one comprehensive set of algorithms that compensate for nearly fifty implementation factors relative to size of the task, inherited baseline, organizational and system environment, and difficulty of the task. SOFTCOST produces mean and variance estimates of software size, implementation productivity, recommended staff level, probable duration, amount of computer resources required, and amount and cost of software documentation. Since the confidence level for a project using mean estimates is small, the user is given the opportunity to enter risk-biased values for effort, duration, and staffing, to achieve higher confidence levels. SOFTCOST then produces a PERT/CPM file with subtask efforts, durations, and precedences defined so as to produce the Work Breakdown Structure (WBS) and schedule having the asked-for overall effort and duration. The SOFTCOST program operates in an interactive environment prompting the user for all of the required input. The program builds the supporting PERT data base in a file for later report generation or revision. The PERT schedule and the WBS schedule may be printed and stored in a

  4. Maintenance cost avoidance through comprehensive condition monitoring

    International Nuclear Information System (INIS)

    Miller, G.P.; McClymonds, S.L.

    1990-01-01

    Condition monitoring, the measurement and trending of a critical parameter for predictive maintenance, has reached new levels of acceptance and application within the utility and manufacturing industry. Commercially available systems extend well beyond traditional vibration-monitoring systems to include such areas as online wear, crack and leak detection, and stress monitoring. The challenge facing industry is to integrate the information generated from condition monitoring. Current studies indicate that the effectiveness of predictive maintenance depends much more on the program that is established to apply the monitoring techniques than on the monitoring equipment itself. This paper presents a five-phase approach to developing a condition monitoring program

  5. Preliminary Multi-Variable Parametric Cost Model for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Hendrichs, Todd

    2010-01-01

    This slide presentation reviews creating a preliminary multi-variable cost model for the contract costs of making a space telescope. There is discussion of the methodology for collecting the data, definition of the statistical analysis methodology, single variable model results, testing of historical models and an introduction of the multi variable models.

  6. Payload maintenance cost model for the space telescope

    Science.gov (United States)

    White, W. L.

    1980-01-01

    An optimum maintenance cost model for the space telescope for a fifteen year mission cycle was developed. Various documents and subsequent updates of failure rates and configurations were made. The reliability of the space telescope for one year, two and one half years, and five years were determined using the failure rates and configurations. The failure rates and configurations were also used in the maintenance simulation computer model which simulate the failure patterns for the fifteen year mission life of the space telescope. Cost algorithms associated with the maintenance options as indicated by the failure patterns were developed and integrated into the model.

  7. Operations and support cost modeling of conceptual space vehicles

    Science.gov (United States)

    Ebeling, Charles

    1994-01-01

    The University of Dayton is pleased to submit this annual report to the National Aeronautics and Space Administration (NASA) Langley Research Center which documents the development of an operations and support (O&S) cost model as part of a larger life cycle cost (LCC) structure. It is intended for use during the conceptual design of new launch vehicles and spacecraft. This research is being conducted under NASA Research Grant NAG-1-1327. This research effort changes the focus from that of the first two years in which a reliability and maintainability model was developed to the initial development of an operations and support life cycle cost model. Cost categories were initially patterned after NASA's three axis work breakdown structure consisting of a configuration axis (vehicle), a function axis, and a cost axis. A revised cost element structure (CES), which is currently under study by NASA, was used to established the basic cost elements used in the model. While the focus of the effort was on operations and maintenance costs and other recurring costs, the computerized model allowed for other cost categories such as RDT&E and production costs to be addressed. Secondary tasks performed concurrent with the development of the costing model included support and upgrades to the reliability and maintainability (R&M) model. The primary result of the current research has been a methodology and a computer implementation of the methodology to provide for timely operations and support cost analysis during the conceptual design activities.

  8. Modelling of air-conditioned and heated spaces

    Energy Technology Data Exchange (ETDEWEB)

    Moehl, U

    1987-01-01

    A space represents a complex system involving numerous components, manipulated variables and disturbances which need to be described if dynamic behaviour of space air is to be determined. A justifiable amount of simulation input is determined by the application of adjusted modelling of the individual components. The determination of natural air exchange in heated spaces and of space-air flow in air-conditioned space are a primary source of uncertainties. (orig.).

  9. Need for Cost Optimization of Space Life Support Systems

    Science.gov (United States)

    Jones, Harry W.; Anderson, Grant

    2017-01-01

    As the nation plans manned missions that go far beyond Earth orbit to Mars, there is an urgent need for a robust, disciplined systems engineering methodology that can identify an optimized Environmental Control and Life Support (ECLSS) architecture for long duration deep space missions. But unlike the previously used Equivalent System Mass (ESM), the method must be inclusive of all driving parameters and emphasize the economic analysis of life support system design. The key parameter for this analysis is Life Cycle Cost (LCC). LCC takes into account the cost for development and qualification of the system, launch costs, operational costs, maintenance costs and all other relevant and associated costs. Additionally, an effective methodology must consider system technical performance, safety, reliability, maintainability, crew time, and other factors that could affect the overall merit of the life support system.

  10. Specific Space Transportation Costs to GEO - Past, Present and Future

    Science.gov (United States)

    Koelle, Dietrich E.

    2002-01-01

    The largest share of space missions is going to the Geosynchronous Orbit (GEO); they have the highest commercial importance. The paper first shows the historic trend of specific transportation costs to GEO from 1963 to 2002. It started out with more than 500 000 /kg(2002-value) and has come down to 36 000 /kg. This reduction looks impressive, however, the reason is NOT improved technology or new techniques but solely the growth of GEO payloads`unit mass. The first GEO satellite in 1963 did have a mass of 36 kg mass (BoL) . This has grown to a weight of 1600 kg (average of all GEO satellites) in the year 2000. Mass in GEO after injection is used here instead of GTO mass since the GTO mass depends on the launch site latitude. The specific cost reduction is only due to the "law-of-scale", valid in the whole transportation business: the larger the payload, the lower the specific transportation cost. The paper shows the actual prices of launch services to GTO by the major launch vehicles. Finally the potential GEO transportation costs of future launch systems are evaluated. What is the potential reduction of specific transportation costs if reusable elements are introduced in future systems ? Examples show that cost reductions up to 75 % seem achievable - compared to actual costs - but only with launch systems optimized according to modern principles of cost engineering. 1. 53rd International Astronautical Congress, World Space Congress Houston 2. First Submission 3. Specific Space Transportation Costs to GEO - Past, Present and Future 4. KOELLE, D.E. 5. IAA.1.1 Launch Vehicles' Cost Engineering and Economic Competitiveness 6. D.E. Koelle; A.E. Goldstein 7. One overhead projector and screen 8. Word file attached 9. KOELLE I have approval to attend the Congress. I am not willing to present this paper at the IAC Public Outreach Program.

  11. Weight and cost forecasting for advanced manned space vehicles

    Science.gov (United States)

    Williams, Raymond

    1989-01-01

    A mass and cost estimating computerized methology for predicting advanced manned space vehicle weights and costs was developed. The user friendly methology designated MERCER (Mass Estimating Relationship/Cost Estimating Relationship) organizes the predictive process according to major vehicle subsystem levels. Design, development, test, evaluation, and flight hardware cost forecasting is treated by the study. This methodology consists of a complete set of mass estimating relationships (MERs) which serve as the control components for the model and cost estimating relationships (CERs) which use MER output as input. To develop this model, numerous MER and CER studies were surveyed and modified where required. Additionally, relationships were regressed from raw data to accommodate the methology. The models and formulations which estimated the cost of historical vehicles to within 20 percent of the actual cost were selected. The result of the research, along with components of the MERCER Program, are reported. On the basis of the analysis, the following conclusions were established: (1) The cost of a spacecraft is best estimated by summing the cost of individual subsystems; (2) No one cost equation can be used for forecasting the cost of all spacecraft; (3) Spacecraft cost is highly correlated with its mass; (4) No study surveyed contained sufficient formulations to autonomously forecast the cost and weight of the entire advanced manned vehicle spacecraft program; (5) No user friendly program was found that linked MERs with CERs to produce spacecraft cost; and (6) The group accumulation weight estimation method (summing the estimated weights of the various subsystems) proved to be a useful method for finding total weight and cost of a spacecraft.

  12. Impact of Chronic Conditions on the Cost of Cancer Care...

    Data.gov (United States)

    U.S. Department of Health & Human Services — According to findings reported in Impact of Chronic Conditions on the Cost of Cancer Care for Medicaid Beneficiaries, published in Volume 2, Issue 4 of the Medicare...

  13. Organizing for low cost space operations - Status and plans

    Science.gov (United States)

    Lee, C.

    1976-01-01

    Design features of the Space Transportation System (vehicle reuse, low cost expendable components, simple payload interfaces, standard support systems) must be matched by economical operational methods to achieve low operating and payload costs. Users will be responsible for their own payloads and will be charged according to the services they require. Efficient use of manpower, simple documentation, simplified test, checkout, and flight planning are firm goals, together with flexibility for quick response to varying user needs. Status of the Shuttle hardware, plans for establishing low cost procedures, and the policy for user charges are discussed.

  14. Lump Sum Moving Cost and Aggregate Office Space Use

    NARCIS (Netherlands)

    G. Romijn

    1997-01-01

    textabstractWhen firms decide to change office space use, in many instances this involves relocation. Relocation involves sizable costs to the firm that can to a large extent be characterized as lump sum, i.e. independent of the change in demand. In this paper we propose and solve a model of the

  15. 'The perception of fear conditioning urban space'

    OpenAIRE

    Fani Bakratsa

    2011-01-01

    The dominant metabolic system within urban environments often involves deep socio-economic inequalities, exploitative productive practices and a persistent sense of alienation among the vast majority of the population. The city itself spawns the conditions both for the development of actual criminality and, more perniciously, for the emergence of an acute perception of fear within the polis. Over the years, this perception has affected a whole array of societal elements including, quite signi...

  16. Low-Load Space Conditioning Needs Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Puttagunta, Srikanth [Consortium for Advanced Residential Buildings, Norwalk, CT (United States)

    2015-05-01

    With limited low-load options in the HVAC market, many new-construction housing units are being fitted with oversized equipment - thus facing penalties in system efficiency, comfort, and cost. To bridge the gap between currently available HVAC equipment and the rising demand for low-load HVAC equipment in the marketplace, HVAC equipment manufacturers need to be fully aware of multifamily buildings and single-family homes market needs. Over the past decade, Steven Winter Associates, Inc. (SWA) has provided certification and consulting services on hundreds of housing projects and has accrued a large pool of data. CARB compiled and analyzed these data to see what the thermal load ranges are in various multifamily apartments and attached single-family home types (duplex and townhouse). In total, design loads from 941 dwellings from SWA's recent multifamily and attached single-family work across the Northeast and Mid-Atlantic were analyzed. Information on the dwelling characteristics, design loads, and the specifications of installed mechanical equipment were analyzed to determine any trends that exist within the dataset.

  17. Spaced taste avoidance conditioning in Lymnaea.

    Science.gov (United States)

    Takigami, Satoshi; Sunada, Hiroshi; Lukowiak, Ken; Sakakibara, Manabu

    2014-01-01

    We succeeded in taste avoidance conditioning with sucrose as the conditional stimulus (CS) and an electrical stimulus (∼1000V, 80μA) as the unconditional stimulus (US). With 15 paired CS-US presentations on a single day, we were able to elicit both short-term memory (STM) and long-term memory (LTM) persisting for at least one week. However, while STM was elicited with 5, 8, 10, and 20 paired presentations of the CS-US on a single day, LTM was not. We found, however, that if we inserted a 3h interval between a first and a second set of CS-US pairings that both 8 and 20 paired CS-US presentations on a single day was now sufficient to cause LTM formation. Exposing snails to bryostatin before or during training enhanced LTM formation such that 8 paired presentations of the CS-US resulted in LTM. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Cost of space-based laser ballistic missile defense.

    Science.gov (United States)

    Field, G; Spergel, D

    1986-03-21

    Orbiting platforms carrying infrared lasers have been proposed as weapons forming the first tier of a ballistic missile defense system under the President's Strategic Defense Initiative. As each laser platform can destroy a limited number of missiles, one of several methods of countering such a system is to increase the number of offensive missiles. Hence it is important to know whether the cost-exchange ratio, defined as the ratio of the cost to the defense of destroying a missile to the cost to the offense of deploying an additional missile, is greater or less than 1. Although the technology to be used in a ballistic missile defense system is still extremely uncertain, it is useful to examine methods for calculating the cost-exchange ratio. As an example, the cost of an orbiting infrared laser ballistic missile defense system employed against intercontinental ballistic missiles launched simultaneously from a small area is compared to the cost of additional offensive missiles. If one adopts lower limits to the costs for the defense and upper limits to the costs for the offense, the cost-exchange ratio comes out substantially greater than 1. If these estimates are confirmed, such a ballistic missile defense system would be unable to maintain its effectiveness at less cost than it would take to proliferate the ballistic missiles necessary to overcome it and would therefore not satisfy the President's requirements for an effective strategic defense. Although the method is illustrated by applying it to a space-based infrared laser system, it should be straightforward to apply it to other proposed systems.

  19. Discounted cost model for condition-based maintenance optimization

    International Nuclear Information System (INIS)

    Weide, J.A.M. van der; Pandey, M.D.; Noortwijk, J.M. van

    2010-01-01

    This paper presents methods to evaluate the reliability and optimize the maintenance of engineering systems that are damaged by shocks or transients arriving randomly in time and overall degradation is modeled as a cumulative stochastic point process. The paper presents a conceptually clear and comprehensive derivation of formulas for computing the discounted cost associated with a maintenance policy combining both condition-based and age-based criteria for preventive maintenance. The proposed discounted cost model provides a more realistic basis for optimizing the maintenance policies than those based on the asymptotic, non-discounted cost rate criterion.

  20. Energy costs of catfish space use as determined by biotelemetry.

    Directory of Open Access Journals (Sweden)

    Ondřej Slavík

    Full Text Available Animals use dispersed resources within their home range (HR during regular day-to-day activities. The high-quality area intensively used by an individual, where critical resources are concentrated, has been designated as the core area (CA. This study aimed to describe how animals utilize energy in the HR and CA assuming that changes would occur according to the size of the used areas. We observed energetic costs of space use in the largest European freshwater predator catfish, Silurus glanis, using physiological sensors. Catfish consumed significantly more energy within the CA compared to the rest of the HR area. In addition, energetic costs of space use within a large area were lower. These results generally indicate that utilization of larger areas is related to less demanding activities, such as patrolling and searching for new resources and mates. In contrast, fish occurrence in small areas appears to be related to energetically demanding use of spatially limited resources.

  1. Method for Controlling Space Transportation System Life Cycle Costs

    Science.gov (United States)

    McCleskey, Carey M.; Bartine, David E.

    2006-01-01

    A structured, disciplined methodology is required to control major cost-influencing metrics of space transportation systems during design and continuing through the test and operations phases. This paper proposes controlling key space system design metrics that specifically influence life cycle costs. These are inclusive of flight and ground operations, test, and manufacturing and infrastructure. The proposed technique builds on today's configuration and mass properties control techniques and takes on all the characteristics of a classical control system. While the paper does not lay out a complete math model, key elements of the proposed methodology are explored and explained with both historical and contemporary examples. Finally, the paper encourages modular design approaches and technology investments compatible with the proposed method.

  2. Invisible Cost Effective Mechanics for Anterior Space Closure.

    Science.gov (United States)

    Jumle, Aatish Vinod; Bagrecha, Saurabh; Gharat, Ninad; Misal, Abhijit; Toshniwal, N G

    2015-01-01

    The shifting paradigm towards invisible orthodontic treatment and also awareness in patients has allured their focus towards the most esthetic treatment approach. Also the lingual treatment is proved successful and is very well accepted by the patients. The problem that persist is its high expenses, which is not affordable by all patients. This article is a effort to treat a simple Class I malocclusion with anterior spacing using a simple, esthetic, Cost effective approach with acceptable results when esthetics plays a priority role.

  3. Conditions and constraints of food processing in space

    Science.gov (United States)

    Fu, B.; Nelson, P. E.; Mitchell, C. A. (Principal Investigator)

    1994-01-01

    Requirements and constraints of food processing in space include a balanced diet, food variety, stability for storage, hardware weight and volume, plant performance, build-up of microorganisms, and waste processing. Lunar, Martian, and space station environmental conditions include variations in atmosphere, day length, temperature, gravity, magnetic field, and radiation environment. Weightlessness affects fluid behavior, heat transfer, and mass transfer. Concerns about microbial behavior include survival on Martian and lunar surfaces and in enclosed environments. Many present technologies can be adapted to meet space conditions.

  4. On the Response of Halophilic Archaea to Space Conditions

    Science.gov (United States)

    Leuko, Stefan; Rettberg, Petra; Pontifex, Ashleigh L.; Burns, Brendan P.

    2014-01-01

    Microorganisms are ubiquitous and can be found in almost every habitat and ecological niche on Earth. They thrive and survive in a broad spectrum of environments and adapt to rapidly changing external conditions. It is of great interest to investigate how microbes adapt to different extreme environments and with modern human space travel, we added a new extreme environment: outer space. Within the last 50 years, technology has provided tools for transporting microbial life beyond Earth’s protective shield in order to study in situ responses to selected conditions of space. This review will focus on halophilic archaea, as, due to their ability to survive in extremes, they are often considered a model group of organisms to study responses to the harsh conditions associated with space. We discuss ground-based simulations, as well as space experiments, utilizing archaea, examining responses and/or resistance to the effects of microgravity and UV in particular. Several halophilic archaea (e.g., Halorubrum chaoviator) have been exposed to simulated and actual space conditions and their survival has been determined as well as the protective effects of halite shown. Finally, the intriguing potential of archaea to survive on other planets or embedded in a meteorite is postulated. PMID:25370029

  5. On the Response of Halophilic Archaea to Space Conditions

    Directory of Open Access Journals (Sweden)

    Stefan Leuko

    2014-02-01

    Full Text Available Microorganisms are ubiquitous and can be found in almost every habitat and ecological niche on Earth. They thrive and survive in a broad spectrum of environments and adapt to rapidly changing external conditions. It is of great interest to investigate how microbes adapt to different extreme environments and with modern human space travel, we added a new extreme environment: outer space. Within the last 50 years, technology has provided tools for transporting microbial life beyond Earth’s protective shield in order to study in situ responses to selected conditions of space. This review will focus on halophilic archaea, as, due to their ability to survive in extremes, they are often considered a model group of organisms to study responses to the harsh conditions associated with space. We discuss ground-based simulations, as well as space experiments, utilizing archaea, examining responses and/or resistance to the effects of microgravity and UV in particular. Several halophilic archaea (e.g., Halorubrum chaoviator have been exposed to simulated and actual space conditions and their survival has been determined as well as the protective effects of halite shown. Finally, the intriguing potential of archaea to survive on other planets or embedded in a meteorite is postulated.

  6. The cost of proactive interference is constant across presentation conditions.

    Science.gov (United States)

    Endress, Ansgar D; Siddique, Aneela

    2016-10-01

    Proactive interference (PI) severely constrains how many items people can remember. For example, Endress and Potter (2014a) presented participants with sequences of everyday objects at 250ms/picture, followed by a yes/no recognition test. They manipulated PI by either using new images on every trial in the unique condition (thus minimizing PI among items), or by re-using images from a limited pool for all trials in the repeated condition (thus maximizing PI among items). In the low-PI unique condition, the probability of remembering an item was essentially independent of the number of memory items, showing no clear memory limitations; more traditional working memory-like memory limitations appeared only in the high-PI repeated condition. Here, we ask whether the effects of PI are modulated by the availability of long-term memory (LTM) and verbal resources. Participants viewed sequences of 21 images, followed by a yes/no recognition test. Items were presented either quickly (250ms/image) or sufficiently slowly (1500ms/image) to produce LTM representations, either with or without verbal suppression. Across conditions, participants performed better in the unique than in the repeated condition, and better for slow than for fast presentations. In contrast, verbal suppression impaired performance only with slow presentations. The relative cost of PI was remarkably constant across conditions: relative to the unique condition, performance in the repeated condition was about 15% lower in all conditions. The cost of PI thus seems to be a function of the relative strength or recency of target items and interfering items, but relatively insensitive to other experimental manipulations. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Space Transportation System Availability Relationships to Life Cycle Cost

    Science.gov (United States)

    Rhodes, Russel E.; Donahue, Benjamin B.; Chen, Timothy T.

    2009-01-01

    Future space transportation architectures and designs must be affordable. Consequently, their Life Cycle Cost (LCC) must be controlled. For the LCC to be controlled, it is necessary to identify all the requirements and elements of the architecture at the beginning of the concept phase. Controlling LCC requires the establishment of the major operational cost drivers. Two of these major cost drivers are reliability and maintainability, in other words, the system's availability (responsiveness). Potential reasons that may drive the inherent availability requirement are the need to control the number of unique parts and the spare parts required to support the transportation system's operation. For more typical space transportation systems used to place satellites in space, the productivity of the system will drive the launch cost. This system productivity is the resultant output of the system availability. Availability is equal to the mean uptime divided by the sum of the mean uptime plus the mean downtime. Since many operational factors cannot be projected early in the definition phase, the focus will be on inherent availability which is equal to the mean time between a failure (MTBF) divided by the MTBF plus the mean time to repair (MTTR) the system. The MTBF is a function of reliability or the expected frequency of failures. When the system experiences failures the result is added operational flow time, parts consumption, and increased labor with an impact to responsiveness resulting in increased LCC. The other function of availability is the MTTR, or maintainability. In other words, how accessible is the failed hardware that requires replacement and what operational functions are required before and after change-out to make the system operable. This paper will describe how the MTTR can be equated to additional labor, additional operational flow time, and additional structural access capability, all of which drive up the LCC. A methodology will be presented that

  8. Long-range planning cost model for support of future space missions by the deep space network

    Science.gov (United States)

    Sherif, J. S.; Remer, D. S.; Buchanan, H. R.

    1990-01-01

    A simple model is suggested to do long-range planning cost estimates for Deep Space Network (DSP) support of future space missions. The model estimates total DSN preparation costs and the annual distribution of these costs for long-range budgetary planning. The cost model is based on actual DSN preparation costs from four space missions: Galileo, Voyager (Uranus), Voyager (Neptune), and Magellan. The model was tested against the four projects and gave cost estimates that range from 18 percent above the actual total preparation costs of the projects to 25 percent below. The model was also compared to two other independent projects: Viking and Mariner Jupiter/Saturn (MJS later became Voyager). The model gave cost estimates that range from 2 percent (for Viking) to 10 percent (for MJS) below the actual total preparation costs of these missions.

  9. Extremophiles survival to simulated space conditions: an astrobiology model study.

    Science.gov (United States)

    Mastascusa, V; Romano, I; Di Donato, P; Poli, A; Della Corte, V; Rotundi, A; Bussoletti, E; Quarto, M; Pugliese, M; Nicolaus, B

    2014-09-01

    In this work we investigated the ability of four extremophilic bacteria from Archaea and Bacteria domains to resist to space environment by exposing them to extreme conditions of temperature, UV radiation, desiccation coupled to low pressure generated in a Mars' conditions simulator. All the investigated extremophilic strains (namely Sulfolobus solfataricus, Haloterrigena hispanica, Thermotoga neapolitana and Geobacillus thermantarcticus) showed a good resistance to the simulation of the temperature variation in the space; on the other hand irradiation with UV at 254 nm affected only slightly the growth of H. hispanica, G. thermantarcticus and S. solfataricus; finally exposition to Mars simulated condition showed that H. hispanica and G. thermantarcticus were resistant to desiccation and low pressure.

  10. Power conditioning for large dc motors for space flight applications

    Science.gov (United States)

    Veatch, Martin S.; Anderson, Paul M.; Eason, Douglas J.; Landis, David M.

    1988-01-01

    The design and performance of a prototype power-conditioning system for use with large brushless dc motors on NASA space missions are discussed in detail and illustrated with extensive diagrams, drawings, and graphs. The 5-kW 8-phase parallel module evaluated here would be suitable for use in the Space Shuttle Orbiter cargo bay. A current-balancing magnetic assembly with low distributed inductance permits high-speed current switching from a low-voltage bus as well as current balancing between parallel MOSFETs.

  11. Low Cost Balloon programme of Indian Centre for Space Physics

    Science.gov (United States)

    Chakrabarti, Sandip Kumar

    2016-07-01

    Indian Centre for Space Physics has launched 89 Missions to near space using single or multiple weather balloons or very light plastic balloons. Basic goal was to capitalize miniaturization of equipments in modern ages. Our typical payload of less than 4kg weight consists of GPS, video camera, cosmic ray detectors, Attitude measurement unit, sunsensor and most importantly a 50-100sqcm X-ray/Gamma-ray detector (usually a scintillator type). The main purpose of the latter is to study spectra of secondary cosmic ray spectra (till our ceiling altitude of 36-42km) over the years and their seasonal variation or variation with solar cycle. We also study solar X-ray spectra, especially of solar flares. We have detected a Gamma Ray Burst (GRB) and pulsars. Our observation of black hole candidates did not yield satisfactory result yet mainly because of poor collimation (~ 10 deg x 10 deg) by lead collimator which introduces strong background also. Our effort with multiple balloon flights enabled us to have long duration flights. We believe that our procedure is very futuristic and yet at an affordable cost.

  12. Low-Cost Gas Heat Pump for Building Space Heating

    Energy Technology Data Exchange (ETDEWEB)

    Garrabrant, Michael [Stone Mountain Technologies, Inc., Johnson City, TN (United States); Keinath, Christopher [Stone Mountain Technologies, Inc., Johnson City, TN (United States)

    2016-10-11

    Gas-fired residential space heating in the U.S is predominantly supplied by furnaces and boilers. These technologies have been approaching their thermodynamic limit over the past 30 years and improvements for high efficiency units have approached a point of diminishing return. Electric heat pumps are growing in popularity but their heating performance at low ambient temperatures is poor. The development of a low-cost gas absorption heat pump would offer a significant improvement to current furnaces and boilers, and in heating dominated climate zones when compared to electric heat pumps. Gas absorption heat pumps (GAHP) exceed the traditional limit of thermal efficiency encountered by typical furnaces and boilers, and maintain high levels of performance at low ambient temperatures. The project team designed and demonstrated two low-cost packaged prototype GAHP space heating systems during the course of this investigation. Led by Stone Mountain Technologies Inc. (SMTI), with support from A.O. Smith, and the Gas Technology Institute (GTI), the cross-functional team completed research and development tasks including cycle modeling, 8× scaling of a compact solution pump, combustion system development, breadboard evaluation, fabrication of two packaged prototype units, third party testing of the first prototype, and the evaluation of cost and energy savings compared to high and minimum efficiency gas options. Over the course of the project and with the fabrication of two Alpha prototypes it was shown that this technology met or exceeded most of the stated project targets. At ambient temperatures of 47, 35, 17 and -13°F the prototypes achieved gas based coefficients of performance of 1.50, 1.44, 1.37, and 1.17, respectively. Both units operated with parasitic loads well below the 750 watt target with the second Alpha prototype operating 75-100 watts below the first Alpha prototype. Modulation of the units at 4:1 was achieved with the project goal of 2:1 modulation

  13. United States comparative costs and absenteeism of diabetic ophthalmic conditions.

    Science.gov (United States)

    Brook, Richard A; Kleinman, Nathan L; Patel, Sunil; Smeeding, Jim E; Beren, Ian A; Turpcu, Adam

    2015-06-01

    This retrospective cohort study examined the impact of diabetic macular edema (DME), diabetic retinopathy (DR), or diabetes on annual health benefit costs and absenteeism in US employees. Claims data from 2001 to 2012 was extracted from the Human Capital Management Services Group Research Reference Database on annual direct/indirect health benefit costs and absences for employees aged ≥ 18 years. Employees with DME, DR, or diabetes were identified by International Classification of Diseases, Ninth Revision, Clinical Modification codes. Employees were divided into two groups, drivers or nondrivers, and examined in separate analyses. For drivers and nondrivers, the DME, DR, and diabetes cohorts were compared with their respective control groups (without diabetes). Two-part regression models controlled for demographics and job-related characteristics. A total of 39,702 driver and 426,549 nondriver employees were identified as having ≥ 1 year's continuous health plan enrollment. Direct medical costs for drivers with DME, DR, or diabetes were $6470, $8021, and $5102, respectively (>2.8 times higher and statistically significant compared with driver controls). Nondrivers with DME and DR incurred significantly higher sick leave and short-term disability costs compared with the nondrivers with diabetes and nondriver controls. In drivers with DME, the majority of days of absence were for short- and long-term disability (12.41 and 11.43 days, respectively). In drivers with DR, the majority of days of absence were for short-term disability (10.70 days). In nondrivers with DME and nondrivers with DR, the majority of days of absence were for sick leave (5.74 and 4.93 days, respectively) and short-term disability (5.08 and 4.93 days, respectively). DME and DR are associated with substantial direct medical cost and absenteeism in this real-world sample of medically insured employees. This research highlights the negative impact of DME and DR on annual costs and absenteeism

  14. Classically integrable boundary conditions for symmetric-space sigma models

    International Nuclear Information System (INIS)

    MacKay, N.J.; Young, C.A.S.

    2004-01-01

    We investigate boundary conditions for the non-linear sigma model on the compact symmetric space G/H. The Poisson brackets and the classical local conserved charges necessary for integrability are preserved by boundary conditions which correspond to involutions which commute with the involution defining H. Applied to SO(3)/SO(2), the non-linear sigma model on S 2 , these yield the great circles as boundary submanifolds. Applied to GxG/G, they reproduce known results for the principal chiral model

  15. Aid Effectiveness, Transaction Costs and Conditionality in the Education Sector

    Science.gov (United States)

    Ashford, Richard; Biswas, Shampa

    2010-01-01

    The reduction of transaction costs is a commonly mentioned yet rarely elaborated goal for aid effectiveness in educational development. The casual use of the concept of transaction costs conceals which costs may be reduced, which costs are required and, indeed, what transaction costs actually are. Examining issues related to harmonizing the…

  16. Low-cost management aspects for developing, producing and operating future space transportation systems

    Science.gov (United States)

    Goehlich, Robert A.; Rücker, Udo

    2005-01-01

    It is believed that a potential means for further significant reduction of the recurrent launch cost, which results also in a stimulation of launch rates of small satellites, is to make the launcher reusable, to increase its reliability and to make it suitable for new markets such as mass space tourism. Therefore, not only launching small satellites with expendable rockets on non-regular flights but also with reusable rockets on regular flights should be considered for the long term. However, developing, producing and operating reusable rockets require a fundamental change in the current "business as usual" philosophy. Under current conditions, it might not be possible to develop, to produce or to operate a reusable vehicle fleet economically. The favorite philosophy is based on "smart business" processes adapted by the authors using cost engineering techniques. In the following paper, major strategies for reducing costs are discussed, which are applied for a representative program proposal.

  17. A Cost Effective System Design Approach for Critical Space Systems

    Science.gov (United States)

    Abbott, Larry Wayne; Cox, Gary; Nguyen, Hai

    2000-01-01

    NASA-JSC required an avionics platform capable of serving a wide range of applications in a cost-effective manner. In part, making the avionics platform cost effective means adhering to open standards and supporting the integration of COTS products with custom products. Inherently, operation in space requires low power, mass, and volume while retaining high performance, reconfigurability, scalability, and upgradability. The Universal Mini-Controller project is based on a modified PC/104-Plus architecture while maintaining full compatibility with standard COTS PC/104 products. The architecture consists of a library of building block modules, which can be mixed and matched to meet a specific application. A set of NASA developed core building blocks, processor card, analog input/output card, and a Mil-Std-1553 card, have been constructed to meet critical functions and unique interfaces. The design for the processor card is based on the PowerPC architecture. This architecture provides an excellent balance between power consumption and performance, and has an upgrade path to the forthcoming radiation hardened PowerPC processor. The processor card, which makes extensive use of surface mount technology, has a 166 MHz PowerPC 603e processor, 32 Mbytes of error detected and corrected RAM, 8 Mbytes of Flash, and I Mbytes of EPROM, on a single PC/104-Plus card. Similar densities have been achieved with the quad channel Mil-Std-1553 card and the analog input/output cards. The power management built into the processor and its peripheral chip allows the power and performance of the system to be adjusted to meet the requirements of the application, allowing another dimension to the flexibility of the Universal Mini-Controller. Unique mechanical packaging allows the Universal Mini-Controller to accommodate standard COTS and custom oversized PC/104-Plus cards. This mechanical packaging also provides thermal management via conductive cooling of COTS boards, which are typically

  18. Cost prediction model for various payloads and instruments for the Space Shuttle Orbiter

    Science.gov (United States)

    Hoffman, F. E.

    1984-01-01

    The following cost parameters of the space shuttle were undertaken: (1) to develop a cost prediction model for various payload classes of instruments and experiments for the Space Shuttle Orbiter; and (2) to show the implications of various payload classes on the cost of: reliability analysis, quality assurance, environmental design requirements, documentation, parts selection, and other reliability enhancing activities.

  19. Estimation of the conditioning and storage costs of low- and intermediate-level solid radioactive wastes

    International Nuclear Information System (INIS)

    Lo Moro, A.; Panciatici, G.

    1977-01-01

    The conditioning and storage costs of low- and intermediate-level solid radioactive wastes are analyzed. The cost of direct labour is assumed as the reference cost for their computation and the storage cost is considered as resulting from the contract cost ''una tantum'' and from the leasing cost. As an example, the cost trends are reported, relevant to the solution adopted at CAMEN (conditioning in concrete containers and storage on concrete open-air bed)

  20. Low Cost Environmental Sensors for Spaceflight: NMP Space Environmental Monitor (SEM) Requirements

    Science.gov (United States)

    Garrett, Henry B.; Buehler, Martin G.; Brinza, D.; Patel, J. U.

    2005-01-01

    An outstanding problem in spaceflight is the lack of adequate sensors for monitoring the space environment and its effects on engineering systems. By adequate, we mean low cost in terms of mission impact (e.g., low price, low mass/size, low power, low data rate, and low design impact). The New Millennium Program (NMP) is investigating the development of such a low-cost Space Environmental Monitor (SEM) package for inclusion on its technology validation flights. This effort follows from the need by NMP to characterize the space environment during testing so that potential users can extrapolate the test results to end-use conditions. The immediate objective of this effort is to develop a small diagnostic sensor package that could be obtained from commercial sources. Environments being considered are: contamination, atomic oxygen, ionizing radiation, cosmic radiation, EMI, and temperature. This talk describes the requirements and rational for selecting these environments and reviews a preliminary design that includes a micro-controller data logger with data storage and interfaces to the sensors and spacecraft. If successful, such a sensor package could be the basis of a unique, long term program for monitoring the effects of the space environment on spacecraft systems.

  1. Predicting Cost and Schedule Growth for Military and Civil Space Systems

    National Research Council Canada - National Science Library

    Rusnock, Christina F

    2008-01-01

    ... for predicting cost and schedule growth. The analysis consists of logistic and multiple regression to assess 21 Department of Defense and 71 National Aeronautics and Space Administration (NASA) space programs...

  2. Logistics: An integral part of cost efficient space operations

    Science.gov (United States)

    Montgomery, Ann D.

    1996-01-01

    The logistics of space programs and its history within NASA are discussed, with emphasis on manned space flight and the Space Shuttle program. The lessons learned and the experience gained during these programs are reported on. Key elements of logistics are highlighted, and the problems and issues that can be expected to arise in relation to the support of long-term space operations and future space programs, are discussed. Such missions include the International Space Station program and the reusable launch vehicle. Possible solutions to the problems identified are outlined.

  3. Update on Multi-Variable Parametric Cost Models for Ground and Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd; Luedtke, Alexander; West, Miranda

    2012-01-01

    Parametric cost models can be used by designers and project managers to perform relative cost comparisons between major architectural cost drivers and allow high-level design trades; enable cost-benefit analysis for technology development investment; and, provide a basis for estimating total project cost between related concepts. This paper reports on recent revisions and improvements to our ground telescope cost model and refinements of our understanding of space telescope cost models. One interesting observation is that while space telescopes are 50X to 100X more expensive than ground telescopes, their respective scaling relationships are similar. Another interesting speculation is that the role of technology development may be different between ground and space telescopes. For ground telescopes, the data indicates that technology development tends to reduce cost by approximately 50% every 20 years. But for space telescopes, there appears to be no such cost reduction because we do not tend to re-fly similar systems. Thus, instead of reducing cost, 20 years of technology development may be required to enable a doubling of space telescope capability. Other findings include: mass should not be used to estimate cost; spacecraft and science instrument costs account for approximately 50% of total mission cost; and, integration and testing accounts for only about 10% of total mission cost.

  4. Humans, 'things' and space: costing hospital infection control interventions.

    Science.gov (United States)

    Page, K; Graves, N; Halton, K; Barnett, A G

    2013-07-01

    Previous attempts at costing infection control programmes have tended to focus on accounting costs rather than economic costs. For studies using economic costs, estimates tend to be quite crude and probably underestimate the true cost. One of the largest costs of any intervention is staff time, but this cost is difficult to quantify and has been largely ignored in previous attempts. To design and evaluate the costs of hospital-based infection control interventions or programmes. This article also discusses several issues to consider when costing interventions, and suggests strategies for overcoming these issues. Previous literature and techniques in both health economics and psychology are reviewed and synthesized. This article provides a set of generic, transferable costing guidelines. Key principles such as definition of study scope and focus on large costs, as well as pitfalls (e.g. overconfidence and uncertainty), are discussed. These new guidelines can be used by hospital staff and other researchers to cost their infection control programmes and interventions more accurately. Copyright © 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  5. Behavior of ionic conducting IPN actuators in simulated space conditions

    Science.gov (United States)

    Fannir, Adelyne; Plesse, Cédric; Nguyen, Giao T. M.; Laurent, Elisabeth; Cadiergues, Laurent; Vidal, Frédéric

    2016-04-01

    The presentation focuses on the performances of flexible all-polymer electroactive actuators under space-hazardous environmental factors in laboratory conditions. These bending actuators are based on high molecular weight nitrile butadiene rubber (NBR), poly(ethylene oxide) (PEO) derivative and poly(3,4-ethylenedioxithiophene) (PEDOT). The electroactive PEDOT is embedded within the PEO/NBR membrane which is subsequently swollen with an ionic liquid as electrolyte. Actuators have been submitted to thermal cycling test between -25 to 60°C under vacuum (2.4 10-8 mbar) and to ionizing Gamma radiations at a level of 210 rad/h during 100 h. Actuators have been characterized before and after space environmental condition ageing. In particular, the viscoelasticity properties and mechanical resistance of the materials have been determined by dynamic mechanical analysis and tensile tests. The evolution of the actuation properties as the strain and the output force have been characterized as well. The long-term vacuuming, the freezing temperature and the Gamma radiations do not affect significantly the thermomechanical properties of conducting IPNs actuators. Only a slight decrease on actuation performances has been observed.

  6. Grooming the Shuttle for cost-effective access to space

    Science.gov (United States)

    Moore, J. W.

    1985-01-01

    An assessment is made of the performance of the Space Shuttle-based Space Transportation System (STS) from the initial flights in 1981 to the present, which has involved the launching of 12 satellites and the retrieval of two. It is expected that the STS will soon be able to schedule 24 routine missions/year, upon the achievement of full operational status for the full fleet of four Space Shuttles and the completion of support facilities at both the Kennedy Space Center and Vandenberg Air Force Base. The prospects for space industrialization efforts based on STS are noted.

  7. The quantum null energy condition in curved space

    Science.gov (United States)

    Fu, Zicao; Koeller, Jason; Marolf, Donald

    2017-11-01

    The quantum null energy condition (QNEC) is a conjectured bound on components (Tkk = Tab ka k^b) of the stress tensor along a null vector k a at a point p in terms of a second k-derivative of the von Neumann entropy S on one side of a null congruence N through p generated by k a . The conjecture has been established for super-renormalizeable field theories at points p that lie on a bifurcate Killing horizon with null tangent k a and for large-N holographic theories on flat space. While the Koeller-Leichenauer holographic argument clearly yields an inequality for general ( p, k^a) , more conditions are generally required for this inequality to be a useful QNEC. For d≤slant 3 , for arbitrary backgroud metric we show that the QNEC is naturally finite and independent of renormalization scheme when the expansion θ of N at the point p vanishes. This is consistent with the original QNEC conjecture which required θ and the shear σab to satisfy θ \\vert _p= \\dotθ\\vert p =0 , σab\\vert _p=0 . But for d=4, 5 more conditions than even these are required. In particular, we also require the vanishing of additional derivatives and a dominant energy condition. In the above cases the holographic argument does indeed yield a finite QNEC, though for d≥slant6 we argue these properties to fail even for weakly isolated horizons (where all derivatives of θ, σab vanish) that also satisfy a dominant energy condition. On the positive side, a corrollary to our work is that, when coupled to Einstein-Hilbert gravity, d ≤slant 3 holographic theories at large N satisfy the generalized second law (GSL) of thermodynamics at leading order in Newton’s constant G. This is the first GSL proof which does not require the quantum fields to be perturbations to a Killing horizon.

  8. Condition Based Maintenance of Space Exploration Vehicles Using Structural Health Monitoring, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Acellent Technologies proposes to develop an autonomous and automated diagnostic system for condition based maintenance (CBM) of safety critical structures for space...

  9. Update on Parametric Cost Models for Space Telescopes

    Science.gov (United States)

    Stahl. H. Philip; Henrichs, Todd; Luedtke, Alexander; West, Miranda

    2011-01-01

    Since the June 2010 Astronomy Conference, an independent review of our cost data base discovered some inaccuracies and inconsistencies which can modify our previously reported results. This paper will review changes to the data base, our confidence in those changes and their effect on various parametric cost models

  10. Reducing Operating Costs by Optimizing Space in Facilities

    Science.gov (United States)

    2012-03-01

    Design: Mapping the High Performance Workscape. Jossey-Bass. San Francisco. Berkman, Elliot. (2012). A Conceptual Guide to Statistics using SPSS. Sage ...Cleaning: Includes labor costs for in-house and contract service, payroll , taxes and fringe benefits, plus salaried supervisors and managers, as well as...Labor costs include payroll , taxes and fringe benefits for employees and contracted workers. Personnel include operating engineers, general

  11. Cost-effective backhaul design using hybrid radio/free-space optical technology

    KAUST Repository

    Douik, Ahmed S.

    2015-06-08

    The deluge of date rate in today\\'s networks poses a cost burden on the backhaul network design. Developing cost efficient backhaul solutions becomes an interesting, yet challenging, problem. Traditional technologies for backhaul networks include either radio-frequency backhauls (RF) or optical fibres (OF). While RF is a cost-effective solution as compared to OF, it supports lower data rate requirements. Another promising backhaul solution that may combine both a high data rate and a relatively low cost is the free-space optics (FSO). FSO, however, is sensitive to nature conditions (e.g., rain, fog, line-ofsight, etc.). A more reliable alternative is, therefore, to combine RF and FSO solutions through a hybrid structure called hybrid RF/FSO. Consider a backhaul network, where the base-stations (BS) can be connected to each other either via OF or hybrid RF/FSO backhaul links. The paper addresses the problem of minimizing the cost of backhaul planning under connectivity and data rates constraints, so as to choose the appropriate costeffective backhaul type between BSs (i.e., either OF or hybrid RF/FSO). The paper solves the problem using graph theory techniques by introducing the corresponding planning graph. It shows that under a specified realistic assumption about the cost of OF and hybrid RF/FSO links, the problem is equivalent to a maximum weight clique problem, which can be solved with moderate complexity. Simulation results show that our proposed solution shows a close-to-optimal performance, especially for practical prices of the hybrid RF/FSO.

  12. Cost-effective backhaul design using hybrid radio/free-space optical technology

    KAUST Repository

    Douik, Ahmed S.; Dahrouj, Hayssam; Al-Naffouri, Tareq Y.; Alouini, Mohamed-Slim

    2015-01-01

    The deluge of date rate in today's networks poses a cost burden on the backhaul network design. Developing cost efficient backhaul solutions becomes an interesting, yet challenging, problem. Traditional technologies for backhaul networks include either radio-frequency backhauls (RF) or optical fibres (OF). While RF is a cost-effective solution as compared to OF, it supports lower data rate requirements. Another promising backhaul solution that may combine both a high data rate and a relatively low cost is the free-space optics (FSO). FSO, however, is sensitive to nature conditions (e.g., rain, fog, line-ofsight, etc.). A more reliable alternative is, therefore, to combine RF and FSO solutions through a hybrid structure called hybrid RF/FSO. Consider a backhaul network, where the base-stations (BS) can be connected to each other either via OF or hybrid RF/FSO backhaul links. The paper addresses the problem of minimizing the cost of backhaul planning under connectivity and data rates constraints, so as to choose the appropriate costeffective backhaul type between BSs (i.e., either OF or hybrid RF/FSO). The paper solves the problem using graph theory techniques by introducing the corresponding planning graph. It shows that under a specified realistic assumption about the cost of OF and hybrid RF/FSO links, the problem is equivalent to a maximum weight clique problem, which can be solved with moderate complexity. Simulation results show that our proposed solution shows a close-to-optimal performance, especially for practical prices of the hybrid RF/FSO.

  13. Towards a Multi-Variable Parametric Cost Model for Ground and Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd

    2016-01-01

    Parametric cost models can be used by designers and project managers to perform relative cost comparisons between major architectural cost drivers and allow high-level design trades; enable cost-benefit analysis for technology development investment; and, provide a basis for estimating total project cost between related concepts. This paper hypothesizes a single model, based on published models and engineering intuition, for both ground and space telescopes: OTA Cost approximately (X) D(exp (1.75 +/- 0.05)) lambda(exp(-0.5 +/- 0.25) T(exp -0.25) e (exp (-0.04)Y). Specific findings include: space telescopes cost 50X to 100X more ground telescopes; diameter is the most important CER; cost is reduced by approximately 50% every 20 years (presumably because of technology advance and process improvements); and, for space telescopes, cost associated with wavelength performance is balanced by cost associated with operating temperature. Finally, duplication only reduces cost for the manufacture of identical systems (i.e. multiple aperture sparse arrays or interferometers). And, while duplication does reduce the cost of manufacturing the mirrors of segmented primary mirror, this cost savings does not appear to manifest itself in the final primary mirror assembly (presumably because the structure for a segmented mirror is more complicated than for a monolithic mirror).

  14. Space shuttle solid rocket booster cost-per-flight analysis technique

    Science.gov (United States)

    Forney, J. A.

    1979-01-01

    A cost per flight computer model is described which considers: traffic model, component attrition, hardware useful life, turnaround time for refurbishment, manufacturing rates, learning curves on the time to perform tasks, cost improvement curves on quantity hardware buys, inflation, spares philosophy, long lead, hardware funding requirements, and other logistics and scheduling constraints. Additional uses of the model include assessing the cost per flight impact of changing major space shuttle program parameters and searching for opportunities to make cost effective management decisions.

  15. CeSiCò - a new technology for lightweight and cost effective space instruments structures and mirrors

    Science.gov (United States)

    Devilliers, Christophe; Krödel, Matthias

    2017-11-01

    Alcatel Alenia Space and ECM have jointly developed a new ceramic material to produce lightweight, stiff, stable and cost effective structures and mirrors for space instrument the CesicÒ. Its intrinsic properties, added to ample manufacturing capabilities allow to manufacture stiff and lightweight cost effective mirrors and structure for space instruments. Different scale 1 flight representative CesicÒ optical structures have been manufactured and successfully tested under very strong dynamic environment and cryogenic condition down to 30K CesicÒ is also envisaged for large and lightweight space telescopes mirrors, a large CesicÒ 1 meter class mirror with an area mass of less than 25 Kg/m2 has been sized again launch loads and WFE performance and manufactured. CesicÒ applicability for large focal plane have been demonstrated through different scale 1 breadboards. Based on these successful results, AlcatelAleniaSpace and ECM are now in position to propose for space this technology with new innovative concepts thanks to the CesicÒ manufacturing capabilities. CesicÒ has therefore been selected for the structure and mirrors parts of a flight instrument payload and the manufacturing of the flight hardware is already underway. An high temperature high gain lightweight antenna breadboard is also under manufacturing for Bepi colombo mission. CesicÒ is therefore a good candidate for future challenging space instruments and is currently proposed for Japan and US space projects.

  16. Desert Cyanobacteria under simulated space and Martian conditions

    Science.gov (United States)

    Billi, D.; Ghelardini, P.; Onofri, S.; Cockell, C. S.; Rabbow, E.; Horneck, G.

    2008-09-01

    isolated from hot desert after prolonged exposure to space and Martian conditions if shielded by few mm of rocky material. In addition, these results further corroborate evidences for the existence in Chroococcidiopsis of mechanisms to both avoid (or limit) and repair DNA damage, which must take place, not only during its prolonged dry storage - when oxidative processes continue even in absence of metabolic activity - but also when dried cells experience additional environmental stressors, including those present in space or on Mars. Indeed, unravelling the DNA repair systems in a desiccation-, radiation- tolerant desert strain of Chroococcidiopsis is the task of ongoing researches at Department of Biology, Università of Rome "Tor Vergata", carried out in the framework of the MoMa project (ASI). Hence, in order to overcome impairments due to the lack of its genome sequence, two genetic approaches were developed, which take advantage of sequenced cyanobacterial genomes. The first one aims to the screening of a prey genomic library of Chroococcidiopsis by using DNA repair baits obtained from Synechocystis PCC 6803. While the second one aims to identify DNA repair genes in the Chroococcidiopsis genome by using evolutionary PCR. Finally, in order to visualize DNA repair factories in Chroococcidiopsis, a GFP-tagging genetic system was developed (Fig. 1). These efforts will contribute to future astrobiological experiments by providing Chroococcidiopsis DNA repair mutants and by offering a real-time monitoring of DNA damaging conditions by using proper GFP fusions.

  17. Understanding the cost bases of Space Shuttle pricing policies for commercial and foreign customers

    Science.gov (United States)

    Stone, Barbara A.

    1984-01-01

    The principles and underlying cost bases of the 1977 and 1982 Space Shuttle Reimbursement Policies are compared and contrasted. Out-of-pocket cost recovery has been chosen as the base of the price for the 1986-1988 time period. With this cost base, it is NASA's intent to recover the total cost of consumables and the launch and flight operations costs added by commercial and foreign customers over the 1986-1988 time period. Beyond 1988, NASA intends to return to its policy of full cost recovery.

  18. Prevalence and Costs of Five Chronic Conditions in Children

    Science.gov (United States)

    Miller, Gabrielle F.; Coffield, Edward; Leroy, Zanie; Wallin, Robin

    2016-01-01

    The objective is to examine the prevalence and health-care costs associated with asthma, epilepsy, hypertension, food allergies, and diabetes in children aged 0-18 years. Prevalence was calculated using 2005-2012 Medical Expenditure Panel Survey (MEPS) data, a population-based, nationally representative sample. Using MEPS, two-part models…

  19. A Method for Estimating Costs and Benefits of Space Assembly and Servicing By Astronauts and Robots

    Science.gov (United States)

    Purves, Lloyd R.; Benfield, Mark (Technical Monitor)

    2002-01-01

    One aspect of designing future space missions is to determine whether Space Assembly and Servicing (SAS) is useful and, if so, what combination of robots and astronauts provides the most effective means of accomplishing it. Certain aspects of these choices, such as the societal value of developing the means for humans to live in space, do not lend themselves to quantification. However, other SAS costs and benefits can be quantified in a manner that can help select the most cost-effective SAS approach. Any space facility, whether it is assembled and serviced or not, entails an eventual replacement cost due to wear and obsolescence. Servicing can reduce this cost by limiting replacement to only failed or obsolete components. However, servicing systems, such as space robots, have their own logistics cost, and astronauts can have even greater logistics requirements. On the other hand, humans can be more capable than robots at performing dexterous and unstructured tasks, which can reduce logistics costs by allowing a reduction in mass of replacement components. Overall, the cost-effectiveness of astronaut SAS depends on its efficiency; and, if astronauts have to be wholly justified by their servicing usefulness, then the serviced space facility has to be large enough to fully occupy them.

  20. Space platforms - A cost effective evolution of Spacelab operation

    Science.gov (United States)

    Stofan, A. J.

    1981-01-01

    The capabilities added to the Shuttle/Spacelab configuration by the addition of the Power Extension Package (PEP), the Power System (PS), and the Science and Applications Space Platforms (SASP) are reviewed with an emphasis on SASP. SASP are intended for placement in orbit by the Shuttle to test new instruments and systems, for clustering of instrumentation, and for servicing, refurbishment, repair, or augmentation by the Shuttle. The PEP permits extended stays in orbit (30 days), and the PS is an orbital solar array and energy storage system acting as a free flying spacecraft. The Shuttle can deliver payloads to the PS or attach to it for extension of the Spacelab operations. Applications of SASP for long term space-based biological experiments are outlined, and the fact that SASP do not increase the required Shuttle in-orbit time is stressed.

  1. Recent developments in low cost stable structures for space

    International Nuclear Information System (INIS)

    Thompson, T.C.; Grastataro, C.; Smith, B.G.

    1994-01-01

    The Los Alamos National Laboratory (LANL) in partnership with Composite Optics Incorporated (COI) is advancing the development of low cost, lightweight, composite technology for use in spacecraft and stable structures. The use of advanced composites is well developed, but the application of an all-composite tracker structure has never been achieved. This paper investigates the application of composite technology to the design and fabrication of an all-composite spacecraft bus for small satellites, using technology directly applicable to central tracking in a high luminosity environment. The satellite program Fast On-Orbit Recording of Transient Events (FORTE) is the second in a series of satellites to be launched into orbit for the US Department of Energy (DOE). This paper will discuss recent developments in the area of low cost composites, used for either spacecraft or ultra stable applications in high energy physics (HEP) detectors. The use of advanced composites is a relatively new development in the area of HEP. The Superconducting Super Collider (SSC) spawned a new generation of Trackers which made extensive use of graphite fiber reinforced plastic (GFRP) composite systems. LANL has designed a structure employing new fabrication technology. This concept will lower the cost of composite structures to a point that they may now compete with conventional materials. This paper will discuss the design, analysis and proposed fabrication of a small satellite structure. Central tracking structures using advanced materials capable of operating in an adverse environment typical of that found in a high luminosity collider could use identical concepts

  2. Better informing decision making with multiple outcomes cost-effectiveness analysis under uncertainty in cost-disutility space.

    Science.gov (United States)

    McCaffrey, Nikki; Agar, Meera; Harlum, Janeane; Karnon, Jonathon; Currow, David; Eckermann, Simon

    2015-01-01

    Comparing multiple, diverse outcomes with cost-effectiveness analysis (CEA) is important, yet challenging in areas like palliative care where domains are unamenable to integration with survival. Generic multi-attribute utility values exclude important domains and non-health outcomes, while partial analyses-where outcomes are considered separately, with their joint relationship under uncertainty ignored-lead to incorrect inference regarding preferred strategies. The objective of this paper is to consider whether such decision making can be better informed with alternative presentation and summary measures, extending methods previously shown to have advantages in multiple strategy comparison. Multiple outcomes CEA of a home-based palliative care model (PEACH) relative to usual care is undertaken in cost disutility (CDU) space and compared with analysis on the cost-effectiveness plane. Summary measures developed for comparing strategies across potential threshold values for multiple outcomes include: expected net loss (ENL) planes quantifying differences in expected net benefit; the ENL contour identifying preferred strategies minimising ENL and their expected value of perfect information; and cost-effectiveness acceptability planes showing probability of strategies minimising ENL. Conventional analysis suggests PEACH is cost-effective when the threshold value per additional day at home (1) exceeds $1,068 or dominated by usual care when only the proportion of home deaths is considered. In contrast, neither alternative dominate in CDU space where cost and outcomes are jointly considered, with the optimal strategy depending on threshold values. For example, PEACH minimises ENL when 1=$2,000 and 2=$2,000 (threshold value for dying at home), with a 51.6% chance of PEACH being cost-effective. Comparison in CDU space and associated summary measures have distinct advantages to multiple domain comparisons, aiding transparent and robust joint comparison of costs and multiple

  3. Better Informing Decision Making with Multiple Outcomes Cost-Effectiveness Analysis under Uncertainty in Cost-Disutility Space

    Science.gov (United States)

    McCaffrey, Nikki; Agar, Meera; Harlum, Janeane; Karnon, Jonathon; Currow, David; Eckermann, Simon

    2015-01-01

    Introduction Comparing multiple, diverse outcomes with cost-effectiveness analysis (CEA) is important, yet challenging in areas like palliative care where domains are unamenable to integration with survival. Generic multi-attribute utility values exclude important domains and non-health outcomes, while partial analyses—where outcomes are considered separately, with their joint relationship under uncertainty ignored—lead to incorrect inference regarding preferred strategies. Objective The objective of this paper is to consider whether such decision making can be better informed with alternative presentation and summary measures, extending methods previously shown to have advantages in multiple strategy comparison. Methods Multiple outcomes CEA of a home-based palliative care model (PEACH) relative to usual care is undertaken in cost disutility (CDU) space and compared with analysis on the cost-effectiveness plane. Summary measures developed for comparing strategies across potential threshold values for multiple outcomes include: expected net loss (ENL) planes quantifying differences in expected net benefit; the ENL contour identifying preferred strategies minimising ENL and their expected value of perfect information; and cost-effectiveness acceptability planes showing probability of strategies minimising ENL. Results Conventional analysis suggests PEACH is cost-effective when the threshold value per additional day at home ( 1) exceeds $1,068 or dominated by usual care when only the proportion of home deaths is considered. In contrast, neither alternative dominate in CDU space where cost and outcomes are jointly considered, with the optimal strategy depending on threshold values. For example, PEACH minimises ENL when 1=$2,000 and 2=$2,000 (threshold value for dying at home), with a 51.6% chance of PEACH being cost-effective. Conclusion Comparison in CDU space and associated summary measures have distinct advantages to multiple domain comparisons, aiding

  4. Valuing urban open space using the travel-cost method and the implications of measurement error.

    Science.gov (United States)

    Hanauer, Merlin M; Reid, John

    2017-08-01

    Urbanization has placed pressure on open space within and adjacent to cities. In recent decades, a greater awareness has developed to the fact that individuals derive multiple benefits from urban open space. Given the location, there is often a high opportunity cost to preserving urban open space, thus it is important for both public and private stakeholders to justify such investments. The goals of this study are twofold. First, we use detailed surveys and precise, accessible, mapping methods to demonstrate how travel-cost methods can be applied to the valuation of urban open space. Second, we assess the degree to which typical methods of estimating travel times, and thus travel costs, introduce bias to the estimates of welfare. The site we study is Taylor Mountain Regional Park, a 1100-acre space located immediately adjacent to Santa Rosa, California, which is the largest city (∼170,000 population) in Sonoma County and lies 50 miles north of San Francisco. We estimate that the average per trip access value (consumer surplus) is $13.70. We also demonstrate that typical methods of measuring travel costs significantly understate these welfare measures. Our study provides policy-relevant results and highlights the sensitivity of urban open space travel-cost studies to bias stemming from travel-cost measurement error. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Development of a Multivariable Parametric Cost Analysis for Space-Based Telescopes

    Science.gov (United States)

    Dollinger, Courtnay

    2011-01-01

    Over the past 400 years, the telescope has proven to be a valuable tool in helping humankind understand the Universe around us. The images and data produced by telescopes have revolutionized planetary, solar, stellar, and galactic astronomy and have inspired a wide range of people, from the child who dreams about the images seen on NASA websites to the most highly trained scientist. Like all scientific endeavors, astronomical research must operate within the constraints imposed by budget limitations. Hence the importance of understanding cost: to find the balance between the dreams of scientists and the restrictions of the available budget. By logically analyzing the data we have collected for over thirty different telescopes from more than 200 different sources, statistical methods, such as plotting regressions and residuals, can be used to determine what drives the cost of telescopes to build and use a cost model for space-based telescopes. Previous cost models have focused their attention on ground-based telescopes due to limited data for space telescopes and the larger number and longer history of ground-based astronomy. Due to the increased availability of cost data from recent space-telescope construction, we have been able to produce and begin testing a comprehensive cost model for space telescopes, with guidance from the cost models for ground-based telescopes. By separating the variables that effect cost such as diameter, mass, wavelength, density, data rate, and number of instruments, we advance the goal to better understand the cost drivers of space telescopes.. The use of sophisticated mathematical techniques to improve the accuracy of cost models has the potential to help society make informed decisions about proposed scientific projects. An improved knowledge of cost will allow scientists to get the maximum value returned for the money given and create a harmony between the visions of scientists and the reality of a budget.

  6. Adjustment in property space markets: taking long-term leases and transaction costs seriously

    NARCIS (Netherlands)

    Englund, P.; Gunnelin, Å.; Hendershott, P.H.; Söderberg, B.

    2008-01-01

    Markets for property space adjust only gradually because tenants and landlords are constrained by long-term leases and transaction and information costs. Not only do rents adjust slowly, but space occupancy, which depends on historical rents, often differs from demand at current rent. This creates

  7. 27 CFR 72.23 - Type and conditions of cost bond.

    Science.gov (United States)

    2010-04-01

    ... PROPERTY Seizures and Forfeitures § 72.23 Type and conditions of cost bond. The cost bond delivered by a claimant to effect removal of the forfeiture status of the property or carrier claimed to the jurisdiction... individual sureties the claimant may deposit collateral as provided in § 72.25. The cost bond shall be...

  8. Space system production cost benefits from contemporary philosophies in management and manufacturing

    Science.gov (United States)

    Rosmait, Russell L.

    1991-01-01

    The cost of manufacturing space system hardware has always been expensive. The Engineering Cost Group of the Program Planning office at Marshall is attempting to account for cost savings that result from new technologies in manufacturing and management. The objective is to identify and define contemporary philosophies in manufacturing and management. The seven broad categories that make up the areas where technological advances can assist in reducing space system costs are illustrated. Included within these broad categories is a list of the processes or techniques that specifically provide the cost savings within todays design, test, production and operations environments. The processes and techniques listed achieve savings in the following manner: increased productivity; reduced down time; reduced scrap; reduced rework; reduced man hours; and reduced material costs. In addition, it should be noted that cost savings from production and processing improvements effect 20 to 40 pct. of production costs whereas savings from management improvements effects 60 to 80 of production cost. This is important because most efforts in reducing costs are spent trying to reduce cost in the production.

  9. Gender and Space: Analysis of Factors Conditioning Equity in the Public Space

    Directory of Open Access Journals (Sweden)

    Pablo Paramo Bernal

    2011-01-01

    Full Text Available This article discusses gender research in urban public space through three different perspectives: the social representations and differentiated uses of space, the division of roles in public and private spaces, and urban planning of public space. The paper gathers and analyses some studies that complement the state of art and literature on women and space giving evidence on how women have been segregated from public space and are victim of gender inequalities. Public space does not exist absolutely nor gender; instead both are socially constructed by social order and reproduced by social practices. Finally, some suggestions for urban planning and research are given in order to respond women’s needs in public space.

  10. Configuration space analysis of common cost functions in radiotherapy beam-weight optimization algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Rowbottom, Carl Graham [Joint Department of Physics, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey (United Kingdom); Webb, Steve [Joint Department of Physics, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey (United Kingdom)

    2002-01-07

    The successful implementation of downhill search engines in radiotherapy optimization algorithms depends on the absence of local minima in the search space. Such techniques are much faster than stochastic optimization methods but may become trapped in local minima if they exist. A technique known as 'configuration space analysis' was applied to examine the search space of cost functions used in radiotherapy beam-weight optimization algorithms. A downhill-simplex beam-weight optimization algorithm was run repeatedly to produce a frequency distribution of final cost values. By plotting the frequency distribution as a function of final cost, the existence of local minima can be determined. Common cost functions such as the quadratic deviation of dose to the planning target volume (PTV), integral dose to organs-at-risk (OARs), dose-threshold and dose-volume constraints for OARs were studied. Combinations of the cost functions were also considered. The simple cost function terms such as the quadratic PTV dose and integral dose to OAR cost function terms are not susceptible to local minima. In contrast, dose-threshold and dose-volume OAR constraint cost function terms are able to produce local minima in the example case studied. (author)

  11. Patient-level costs of major cardiovascular conditions: a review of the international literature.

    Science.gov (United States)

    Nicholson, Gina; Gandra, Shravanthi R; Halbert, Ronald J; Richhariya, Akshara; Nordyke, Robert J

    2016-01-01

    Robust cost estimates of cardiovascular (CV) events are required for assessing health care interventions aimed at reducing the economic burden of major adverse CV events. This review synthesizes international cost estimates of CV events. MEDLINE database was searched electronically for English language studies published during 2007-2012, with cost estimates for CV events of interest - unstable angina, myocardial infarction, heart failure, stroke, and CV revascularization. Included studies provided at least one estimate of patient-level direct costs in adults for any identified country. Information on study characteristics and cost estimates were collected. All costs were adjusted for inflation to 2013 values. Across the 114 studies included, the average cost was US $6,466 for unstable angina, $11,664 for acute myocardial infarction, $11,686 for acute heart failure, $11,635 for acute ischemic stroke, $37,611 for coronary artery bypass graft, and $13,501 for percutaneous coronary intervention. The ranges for cost estimates varied widely across countries with US cost estimate being at least twice as high as European Union costs for some conditions. Few studies were found on populations outside the US and European Union. This review showed wide variation in the cost of CV events within and across countries, while showcasing the continuing economic burden of CV disease. The variability in costs was primarily attributable to differences in study population, costing methodologies, and reporting differences. Reliable cost estimates for assessing economic value of interventions in CV disease are needed.

  12. Much Lower Launch Costs Make Resupply Cheaper than Recycling for Space Life Support

    Science.gov (United States)

    Jones, Harry W.

    2017-01-01

    The development of commercial launch vehicles by SpaceX has greatly reduced the cost of launching mass to Low Earth Orbit (LEO). Reusable launch vehicles may further reduce the launch cost per kilogram. The new low launch cost makes open loop life support much cheaper than before. Open loop systems resupply water and oxygen in tanks for crew use and provide disposable lithium hydroxide (LiOH) in canisters to remove carbon dioxide. Short human space missions such as Apollo and shuttle have used open loop life support, but the long duration International Space Station (ISS) recycles water and oxygen and removes carbon dioxide with a regenerative molecular sieve. These ISS regenerative and recycling life support systems have significantly reduced the total launch mass needed for life support. But, since the development cost of recycling systems is much higher than the cost of tanks and canisters, the relative cost savings have been much less than the launch mass savings. The Life Cycle Cost (LCC) includes development, launch, and operations. If another space station was built in LEO, resupply life support would be much cheaper than the current recycling systems. The mission most favorable to recycling would be a long term lunar base, since the resupply mass would be large, the proximity to Earth would reduce the need for recycling reliability and spares, and the launch cost would be much higher than for LEO due to the need for lunar transit and descent propulsion systems. For a ten-year lunar base, the new low launch costs make resupply cheaper than recycling systems similar to ISS life support.

  13. Cost-effective and robust mitigation of space debris in low earth orbit

    Science.gov (United States)

    Walker, R.; Martin, C.

    It is predicted that the space debris population in low Earth orbit (LEO) will continue to grow and in an exponential manner in the long-term due to an increasing rate of collisions between large objects, unless internationally-accepted space debris mitigation measures are adopted soon. Such measures are aimed at avoiding the future generation of space debris objects and primarily need to be effective in preventing significant long-term growth in the debris population, even in the potential scenario of an increase in future space activity. It is also important that mitigation measures can limit future debris population levels, and therefore the underlying collision risk to space missions, to the lowest extent possible. However, for their wide acceptance, the cost of implementation associated with mitigation measures needs to be minimised as far as possible. Generally, a lower collision risk will cost more to achieve and vice versa, so it is necessary to strike a balance between cost and risk in order to find a cost-effective set of mitigation measures. In this paper, clear criteria are established in order to assess the cost-effectiveness of space debris mitigation measures. A full cost-risk-benefit trade-off analysis of numerous mitigation scenarios is presented. These scenarios consider explosion prevention and post-mission disposal of space systems, including de-orbiting to limited lifetime orbits and re-orbiting above the LEO region. The ESA DELTA model is used to provide long-term debris environment projections for these scenarios as input to the benefit and risk parts of the trade-off analysis. Manoeuvre requirements for the different post-mission disposal scenarios were also calculated in order to define the cost-related element. A 25-year post-mission lifetime de-orbit policy, combined with explosion prevention and mission-related object limitation, was found to be the most cost-effective solution to the space debris problem in LEO. This package would also

  14. Power Absorption by Closely Spaced Point Absorbers in Constrained Conditions

    DEFF Research Database (Denmark)

    De Backer, G.; Vantorre, M.; Beels, C.

    2010-01-01

    The performance of an array of closely spaced point absorbers is numerically assessed in a frequency domain model Each point absorber is restricted to the heave mode and is assumed to have its own linear power take-off (PTO) system Unidirectional irregular incident waves are considered......, representing the wave climate at Westhinder on the Belgian Continental Shelf The impact of slamming, stroke and force restrictions on the power absorption is evaluated and optimal PTO parameters are determined For multiple bodies optimal control parameters (CP) are not only dependent on the incoming waves...

  15. A Conditional Fourier-Feynman Transform and Conditional Convolution Product with Change of Scales on a Function Space II

    Directory of Open Access Journals (Sweden)

    Dong Hyun Cho

    2017-01-01

    Full Text Available Using a simple formula for conditional expectations over continuous paths, we will evaluate conditional expectations which are types of analytic conditional Fourier-Feynman transforms and conditional convolution products of generalized cylinder functions and the functions in a Banach algebra which is the space of generalized Fourier transforms of the measures on the Borel class of L2[0,T]. We will then investigate their relationships. Particularly, we prove that the conditional transform of the conditional convolution product can be expressed by the product of the conditional transforms of each function. Finally we will establish change of scale formulas for the conditional transforms and the conditional convolution products. In these evaluation formulas and change of scale formulas, we use multivariate normal distributions so that the conditioning function does not contain present positions of the paths.

  16. Health plan utilization and costs of specialty drugs within 4 chronic conditions.

    Science.gov (United States)

    Gleason, Patrick P; Alexander, G Caleb; Starner, Catherine I; Ritter, Stephen T; Van Houten, Holly K; Gunderson, Brent W; Shah, Nilay D

    2013-09-01

    Drugs are most typically defined as specialty because they are expensive; however, other criteria used to define a drug as specialty include biologic drugs, the need to inject or infuse the drug, the requirement for special handling, or drug availability only via a limited distribution network. Specialty drugs play an increasingly important role in the treatment of chronic conditions such as multiple sclerosis (MS), rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD), yet little is known regarding the comprehensive medical and pharmacy benefit utilization and cost trends for these conditions. To describe MS, RA, psoriasis, and IBD trends for condition prevalence, treatment with specialty drugs, specialty costs, nonspecialty costs, and total direct costs of care within the medical and pharmacy benefits. This was a descriptive analysis of a commercially insured population made up of 1 million members, using integrated medical and pharmacy administrative claims data from 2008 to 2010. Analyses were limited to continuously enrolled commercially insured individuals less than 65 years of age. Condition-specific cohorts for MS, RA, psoriasis, and IBD were defined using standardized criteria. Trends in condition prevalence, specialty drug use for the conditions, and direct total cost of care were analyzed. The direct costs were subcategorized into the following: medical benefit specialty drug costs, medical benefit all other costs, pharmacy benefit specialty drug costs, and pharmacy benefit all other costs. Trends and compound annual growth rates were calculated for the total cost of care and subcategory costs from 2008 through 2010. Condition prevalence ranged from a low of 1,720 per million members for MS to a high of 4,489 per million members for RA. Psoriasis and MS condition prevalence rates were unchanged over the 3 years; however, IBD prevalence increased 7.0%, and RA prevalence increased 9.7%. The rate of specialty drug use was lowest for IBD

  17. Evaluation of supercapacitors for space applications under thermal vacuum conditions

    Science.gov (United States)

    Chin, Keith C.; Green, Nelson W.; Brandon, Erik J.

    2018-03-01

    Commercially available supercapacitor cells from three separate vendors were evaluated for use in a space environment using thermal vacuum (Tvac) testing. Standard commercial cells are not hermetically sealed, but feature crimp or double seam seals between the header and the can, which may not maintain an adequate seal under vacuum. Cells were placed in a small vacuum chamber, and cycled between three separate temperature set points. Charging and discharging of cells was executed following each temperature soak, to confirm there was no significant impact on performance. A final electrical performance check, visual inspection and mass check following testing were also performed, to confirm the integrity of the cells had not been compromised during exposure to thermal cycling under vacuum. All cells tested were found to survive this testing protocol and exhibited no significant impact on electrical performance.

  18. Modelling the Cost Performance of a Given Logistics Network Operating Under Regular and Irregular Conditions

    NARCIS (Netherlands)

    Janic, M.

    2009-01-01

    This paper develops an analytical model for the assessment of the cost performance of a given logistics network operating under regular and irregular (disruptive) conditions. In addition, the paper aims to carry out a sensitivity analysis of this cost with respect to changes of the most influencing

  19. The Effect of Conditional Conservatism and Agency Cost on Investment-Cashflow Sensitivity

    Directory of Open Access Journals (Sweden)

    Bima Abdi Wibawa

    2018-01-01

    Full Text Available This research aims to give empirical evidence of the effect of conditional conservatism on company’s investment-cashflow sensitivity, and whether the impact is stronger in high agency cost firms compare to in low agency cost firms. This research uses dividend payout ratio to measure the agency cost because this study uses Indonesia as a research context where companies in Indonesia majority have concentrated ownership and funding through debt so that agency conflict that appears more dominant is the conflict of agency type two and three. This study uses the sample from manufacturing companies listed on Indonesia Stock Exchange during the period 2008-2012. The total observation in this research is 474 firm years, which 152 of the samples is classified as high agency cost firms and 322 sample as low agency cost firms. The result shows that as the recognition of economic losses becomes more timely, the sensitivity of firm investment to cashflow decreases. Conditional conservatism decreases investment-cashflow sensitivity in low agency cost firms but increases the sensitivity in high agency cost firms. In fact, before implementation of conditional conservatism, high agency cost firms have smaller investment cashflow sensitivity compared to the low agency cost one.

  20. Chaotic inflation as an attractor in initial-condition space

    International Nuclear Information System (INIS)

    Kung, J.H.; Brandenberger, R.H.

    1990-01-01

    We study the evolution of scalar field inhomogeneities in the preinflationary phase of an inflationary universe. We decompose the scalar field configuration in Fourier modes and consider initial conditions in which more than one mode is excited. We find that the long-wavelength modes are stable against perturbations due to short-wavelength excitations and that chaotic inflation results even if at the initial time the short waves contain most of the energy density

  1. Engineering and Fabrication Considerations for Cost-Effective Space Reactor Shield Development

    International Nuclear Information System (INIS)

    Berg, Thomas A.; Disney, Richard K.

    2004-01-01

    Investment in developing nuclear power for space missions cannot be made on the basis of a single mission. Current efforts in the design and fabrication of the reactor module, including the reactor shield, must be cost-effective and take into account scalability and fabricability for planned and future missions. Engineering considerations for the shield need to accommodate passive thermal management, varying radiation levels and effects, and structural/mechanical issues. Considering these challenges, design principles and cost drivers specific to the engineering and fabrication of the reactor shield are presented that contribute to lower recurring mission costs

  2. From COST 271 to 296 EU actions on ionospheric monitoring and modelling for terrestrial and Earth space radio systems

    Science.gov (United States)

    Zolesi, B.; Cander, Lj. R.; Altadill, D.

    The ionospheric community has long been aware that co-operative research on an international basis is essential to deal with temporal and spatial changes in the ionosphere that influence the performance of terrestrial and Earth-space radio systems. The EU COST (Co-operation in the field of Scientific and Technical Research) 271 Action on "Effects of the Upper Atmosphere on Terrestrial and Earth-space Communications" has had during the period of October 2000-August 2004 the following main objectives: (1) to evaluate the influence of upper atmospheric conditions on terrestrial and Earth-space communications, (2) to develop methods and techniques to improve ionospheric models over Europe for telecommunication and navigation applications and (3) to transfer the results to the appropriate radiocommunication study groups of the International Telecommunication Union (ITU-R) and other national and international organizations dealing with the modern communication systems. At the beginning of 2005 the new 296 Action in the COST Telecommunications, Information Science and Technology domain on "Mitigation of Ionospheric Effects on Radio Systems (MIERS)" was approved for the period 2005-2009. The main objectives of the MIERS are: (a) to support and enhanced the existing European facilities for historical and real-time digital ionospheric data collection and exchange; (b) to develop an integrated approach to ionospheric modelling, create the mechanism needed to ingest processed data into models, extend and develop suitable mitigation models and define the protocols needed to link models together; and (c) to strengthen the areas of expertise that already exist by stimulating closer cooperation between scientists and users, focusing the scope of all the previous COST ionospheric related studies to the mitigation of ionospheric effects on radio systems. This paper summarises briefly how the major objectives of the COST271 Action have been achieved and what are the most important

  3. Patient-level costs of major cardiovascular conditions: a review of the international literature

    Directory of Open Access Journals (Sweden)

    Nicholson G

    2016-09-01

    Full Text Available Gina Nicholson,1 Shravanthi R Gandra,2 Ronald J Halbert,1 Akshara Richhariya,2 Robert J Nordyke1 1ICON, El Segundo, 2Amgen Inc., Thousand Oaks, CA, USA Objective: Robust cost estimates of cardiovascular (CV events are required for assessing health care interventions aimed at reducing the economic burden of major adverse CV events. This review synthesizes international cost estimates of CV events.Methods: MEDLINE database was searched electronically for English language studies published during 2007-2012, with cost estimates for CV events of interest – unstable angina, myocardial infarction, heart failure, stroke, and CV revascularization. Included studies provided at least one estimate of patient-level direct costs in adults for any identified country. Information on study characteristics and cost estimates were collected. All costs were adjusted for inflation to 2013 values.Results: Across the 114 studies included, the average cost was US $6,466 for unstable angina, $11,664 for acute myocardial infarction, $11,686 for acute heart failure, $11,635 for acute ischemic stroke, $37,611 for coronary artery bypass graft, and $13,501 for percutaneous coronary intervention. The ranges for cost estimates varied widely across countries with US cost estimate being at least twice as high as European Union costs for some conditions. Few studies were found on populations outside the US and European Union.Conclusion: This review showed wide variation in the cost of CV events within and across countries, while showcasing the continuing economic burden of CV disease. The variability in costs was primarily attributable to differences in study population, costing methodologies, and reporting differences. Reliable cost estimates for assessing economic value of interventions in CV disease are needed. Keywords: cardiovascular diseases, health care costs, hospitalization economics, follow-up studies

  4. Increased root production in soybeans grown under space flight conditions.

    Science.gov (United States)

    Levine, H. G.; Piastuch, W. C.

    The GENEX ({Gen}e {Ex}pression) spaceflight experiment (flown on STS-87) was developed to investigate whether direct and/or indirect effects of microgravity are perceived as an external stimulus for soybean seedling response. Protocols were designed to optimize root and shoot formation, gas exchange and moisture uniformity. Six surface sterilized soybean seeds (Glycine max cv McCall) were inserted into each of 32 autoclaved plastic seed growth pouches containing an inner germination paper sleeve (for a total of 192 seeds). The pouches were stowed within a mid-deck locker until Mission Flight Day 10, at which time an astronaut added water to each pouch (thereby initiating the process of seed germination on-orbit), and subsequently transferred them to four passive, light-tight aluminum canisters called BRIC-60s (Biological Research In Canisters). We report here on the morphological characteristics of: (1) the recovered flight material, (2) the corresponding ground control population, plus (3) additional controls grown on the ground under clinostat conditions. No significant growth differences were found between the flight, ground control and clinorotated treatments for either the cotyledons or hypocotyls. There were, however, significantly longer primary roots produced in the flight population relative to the ground control population, which in turn had significantly longer primary roots than the clinorotated population. This same pattern was observed relative to the production of lateral roots (flight > control > clinorotated). Taken together with previous literature reports, we believe that there is now sufficient evidence to conclude that plants grown under conditions of microgravity will generally exhibit enhanced root production relative to their ground control counterparts. The mechanism underlying this phenomenon is open to speculation. Funded under NASA Contract NAS10-12180.

  5. Space Technology Demonstrations Using Low Cost, Short-Schedule Airborne and Range Facilities at the Dryden Flight Research Center

    Science.gov (United States)

    Carter, John; Kelly, John; Jones, Dan; Lee, James

    2013-01-01

    There is a national effort to expedite advanced space technologies on new space systems for both government and commercial applications. In order to lower risk, these technologies should be demonstrated in a relevant environment before being installed in new space systems. This presentation introduces several low cost, short schedule space technology demonstrations using airborne and range facilities available at the Dryden Flight Research Center.

  6. Concepts for Life Cycle Cost Control Required to Achieve Space Transportation Affordability and Sustainability

    Science.gov (United States)

    Rhodes, Russel E.; Zapata, Edgar; Levack, Daniel J. H.; Robinson, John W.; Donahue, Benjamin B.

    2009-01-01

    Cost control must be implemented through the establishment of requirements and controlled continually by managing to these requirements. Cost control of the non-recurring side of life cycle cost has traditionally been implemented in both commercial and government programs. The government uses the budget process to implement this control. The commercial approach is to use a similar process of allocating the non-recurring cost to major elements of the program. This type of control generally manages through a work breakdown structure (WBS) by defining the major elements of the program. If the cost control is to be applied across the entire program life cycle cost (LCC), the approach must be addressed very differently. A functional breakdown structure (FBS) is defined and recommended. Use of a FBS provides the visibifity to allow the choice of an integrated solution reducing the cost of providing many different elements of like function. The different functional solutions that drive the hardware logistics, quantity of documentation, operational labor, reliability and maintainability balance, and total integration of the entire system from DDT&E through the life of the program must be fully defined, compared, and final decisions made among these competing solutions. The major drivers of recurring cost have been identified and are presented and discussed. The LCC requirements must be established and flowed down to provide control of LCC. This LCC control will require a structured rigid process similar to the one traditionally used to control weight/performance for space transportation systems throughout the entire program. It has been demonstrated over the last 30 years that without a firm requirement and methodically structured cost control, it is unlikely that affordable and sustainable space transportation system LCC will be achieved.

  7. Studies on gene expressions analyses for Arabidopsis thaliana plants stimulated by space flight condition

    Science.gov (United States)

    Lu, Jinying; Liu, Min; Pan, Yi; Li, Huasheng

    We carried out whole-genome microarray to screen the transcript profile of Arabidopsis thaliana seedlings after three treatment: space microgravity condition( Seedlings grown in microgravity state of space flight of SIMBOX on Shenzhou-8), 1g centrifugal force in space(Seedlings grown in 1g centrifugal force state of space flight of SIMBOX on Shenzhou-8) and ground control. The result of microarray analysis is as followed: There were 368 genes significantly differentially expressed in space microgravity condition compared with that in 1g centrifuge space condition. Space radiation caused 246 genes significantly differentially expressed between seedlings in 1g centrifuge space condition and ground control. Space conditions (including microgravity and radiation) caused 621 genes significantly differentially expressed between seedlings in space microgravity condition and ground control. Microgravity and radiation as a single factor can cause plant gene expression change, but two factors synergism can produce some new effects on plant gene expression. The function of differential expression genes were analyst by bioinformatics, and we found the expression of genes related with stress were more different, such as the dehydration of protein (dehydrin Xero2) expression is up-regulated 57 times; low-temperature-induced protein expression is up-regulated in 49 times; heat shock protein expression is up-regulated 20 times; transcription factor DREB2A expression increase 25 times; protein phosphatase 2C expression is up-regulated 14 times; transcription factor NAM-like protein expression is up-regulated 13 times; cell wall metabolism related genes (xyloglucan, endo-1, 4-beta-D-glucanase) expression is down-regulated in 15 times. The results provide scientific data for the mechanism of space mutation.

  8. A nuclear waste deposit in space - the ultimate solution for low-cost and safe disposal

    International Nuclear Information System (INIS)

    Ruppe, H.O.; Hayn, D.; Braitinger, M.; Schmucker, R.H.

    1980-01-01

    The disposal of nuclear high-active waste (HAW) is representative for the problem of burdening the environment with highly active or toxic waste products at present and in the future. Safe disposal methods on Earth are technically very difficult to achieve and the costs of establishment and maintenance of such plants are extremely high. Furthermore the emotionally based rejection by a wide sector of the population gives sufficient reason to look for new solutions. Here, space technology can offer a real alternative - a waste deposit in space. With the Space Transportation System, which shall soon be operative, and the resulting high flight frequencies it will be possible to transport all future HAW into space at economical casts. (orig.) [de

  9. Comparing Value of Urban Green Space Using Contingent Valuation and Travel Cost Methods

    Science.gov (United States)

    Chintantya, Dea; Maryono

    2018-02-01

    Green urban open space are an important element of the city. They gives multiple benefits for social life, human health, biodiversity, air quality, carbon sequestration, and water management. Travel Cost Method (TCM) and Contingent Valuation Method (CVM) are the most frequently used method in various studies that assess environmental good and services in monetary term for valuing urban green space. Both of those method are determined the value of urban green space through willingness to pay (WTP) for ecosystem benefit and collected data through direct interview and questionnaire. Findings of this study showed the weaknesses and strengths of both methods for valuing urban green space and provided factors influencing the probability of user's willingness to pay in each method.

  10. Comparing Value of Urban Green Space Using Contingent Valuation and Travel Cost Methods

    Directory of Open Access Journals (Sweden)

    Chintantya Dea

    2018-01-01

    Full Text Available Green urban open space are an important element of the city. They gives multiple benefits for social life, human health, biodiversity, air quality, carbon sequestration, and water management. Travel Cost Method (TCM and Contingent Valuation Method (CVM are the most frequently used method in various studies that assess environmental good and services in monetary term for valuing urban green space. Both of those method are determined the value of urban green space through willingness to pay (WTP for ecosystem benefit and collected data through direct interview and questionnaire. Findings of this study showed the weaknesses and strengths of both methods for valuing urban green space and provided factors influencing the probability of user’s willingness to pay in each method.

  11. Report by the International Space Station (ISS) Management and Cost Evaluation (IMCE) Task Force

    Science.gov (United States)

    Young, A. Thomas; Kellogg, Yvonne (Technical Monitor)

    2001-01-01

    The International Space Station (ISS) Management and Cost Evaluation Task Force (IMCE) was chartered to conduct an independent external review and assessment of the ISS cost, budget, and management. In addition, the Task Force was asked to provide recommendations that could provide maximum benefit to the U.S. taxpayers and the International Partners within the President's budget request. The Task Force has made the following principal findings: (1) The ISS Program's technical achievements to date, as represented by on-orbit capability, are extraordinary; (2) The Existing ISS Program Plan for executing the FY 02-06 budget is not credible; (3) The existing deficiencies in management structure, institutional culture, cost estimating, and program control must be acknowledged and corrected for the Program to move forward in a credible fashion; (4) Additional budget flexibility, from within the Office of Space Flight (OSF) must be provided for a credible core complete program; (5) The research support program is proceeding assuming the budget that was in place before the FY02 budget runout reduction of $1B; (6) There are opportunities to maximize research on the core station program with modest cost impact; (7) The U.S. Core Complete configuration (three person crew) as an end-state will not achieve the unique research potential of the ISS; (8) The cost estimates for the U.S.-funded enhancement options (e.g., permanent seven person crew) are not sufficiently developed to assess credibility. After these findings, the Task Force has formulated several primary recommendations which are published here and include: (1) Major changes must be made in how the ISS program is managed; (2) Additional cost reductions are required within the baseline program; (3) Additional funds must be identified and applied from the Human Space Flight budget; (4) A clearly defined program with a credible end-state, agreed to by all stakeholders, must be developed and implemented.

  12. Parametric Cost Modeling of Space Missions Using the Develop New Projects (DMP) Implementation Process

    Science.gov (United States)

    Rosenberg, Leigh; Hihn, Jairus; Roust, Kevin; Warfield, Keith

    2000-01-01

    This paper presents an overview of a parametric cost model that has been built at JPL to estimate costs of future, deep space, robotic science missions. Due to the recent dramatic changes in JPL business practices brought about by an internal reengineering effort known as develop new products (DNP), high-level historic cost data is no longer considered analogous to future missions. Therefore, the historic data is of little value in forecasting costs for projects developed using the DNP process. This has lead to the development of an approach for obtaining expert opinion and also for combining actual data with expert opinion to provide a cost database for future missions. In addition, the DNP cost model has a maximum of objective cost drivers which reduces the likelihood of model input error. Version 2 is now under development which expands the model capabilities, links it more tightly with key design technical parameters, and is grounded in more rigorous statistical techniques. The challenges faced in building this model will be discussed, as well as it's background, development approach, status, validation, and future plans.

  13. REUSABLE PROPULSION ARCHITECTURE FOR SUSTAINABLE LOW-COST ACCESS TO SPACE

    Science.gov (United States)

    Bonometti, Joseph; Frame, Kyle L.; Dankanich, John W.

    2005-01-01

    Two transportation architecture changes are presented at either end of a conventional two-stage rocket flight: 1) Air launch using a large, conventional, pod hauler design (i.e., Crossbow)ans 2) Momentum exchange tether (i.e., an in-space asset like MXER). Air launch has ana analytically justified cost reduction of approx. 10%, but its intangible benefits suggest real-world operations cost reductions much higher: 1) Inherent launch safety; 2) Mission Risk Reduction; 3) Favorable payload/rocket limitations; and 4) Leveraging the aircraft for other uses (military transport, commercial cargo, public outreach activities, etc.)

  14. Some common random fixed point theorems for contractive type conditions in cone random metric spaces

    Directory of Open Access Journals (Sweden)

    Saluja Gurucharan S.

    2016-08-01

    Full Text Available In this paper, we establish some common random fixed point theorems for contractive type conditions in the setting of cone random metric spaces. Our results unify, extend and generalize many known results from the current existing literature.

  15. Cost-Loss Analysis of Ensemble Solar Wind Forecasting: Space Weather Use of Terrestrial Weather Tools

    Science.gov (United States)

    Henley, E. M.; Pope, E. C. D.

    2017-12-01

    This commentary concerns recent work on solar wind forecasting by Owens and Riley (2017). The approach taken makes effective use of tools commonly used in terrestrial weather—notably, via use of a simple model—generation of an "ensemble" forecast, and application of a "cost-loss" analysis to the resulting probabilistic information, to explore the benefit of this forecast to users with different risk appetites. This commentary aims to highlight these useful techniques to the wider space weather audience and to briefly discuss the general context of application of terrestrial weather approaches to space weather.

  16. Conditions and costs for renewables electricity grid connection: Examples in Europe

    International Nuclear Information System (INIS)

    Swider, Derk J.; Beurskens, Luuk; Davidson, Sarah; Twidell, John; Pyrko, Jurek; Prueggler, Wolfgang; Auer, Hans; Vertin, Katarina; Skema, Romualdas

    2008-01-01

    This paper compares conditions and costs for RES-E grid connection in selected European countries. These are Germany, the Netherlands, the United Kingdom, Sweden, Austria, Lithuania and Slovenia. Country specific case studies are presented for wind onshore and offshore, biomass and photovoltaic power systems, as based on literature reviews and stakeholder interviews. It is shown that, especially for wind offshore, the allocation of grid connection costs can form a significant barrier for the installation of new RES-E generation if the developer has to bear all such costs. If energy policy makers want to reduce the barriers for new large-scale RES-E deployment, then it is concluded that the grid connection costs should be covered by the respective grid operator. These costs may then be recouped by increasing consumer tariffs for the use of the grid. (author)

  17. Estimation of absorbed dose for poor shields under conditions of near-earth space flight

    International Nuclear Information System (INIS)

    Konyukov, V.V.; Krajnyukov, V.I.; Trufanov, A.I.

    1995-01-01

    Estimation of electron absorbed dose in materials of a space vehicle for poor shields under conditions of near-earth space flight is carried out. Impact of power and angular distribution of incidence electrons and radiation scattering processes under conditions of complex geometry and multitude of materials of flight vehicle elements and nodes is studied through simulator model by example of isolating layer of aluminium-polyethylene assembly. 3 refs.; 2 figs

  18. A study of space station needs, attributes and architectural options, volume 2, technical. Book 3: Economic benefits, costs and programmatics

    Science.gov (United States)

    1983-01-01

    The economic benefits, cost analysis, and industrial uses of the manned space station are investigated. Mission payload costs are examined in relation to alternative architectures and projected technological evolution. Various approaches to industrial involvement for financing, development, and marketing of space station resources are described.

  19. The high price of depression: Family members' health conditions and health care costs.

    Science.gov (United States)

    Ray, G Thomas; Weisner, Constance M; Taillac, Cosette J; Campbell, Cynthia I

    2017-05-01

    To compare the health conditions and health care costs of family members of patients diagnosed with a Major Depressive Disorder (MDD) to family members of patients without an MDD diagnosis. Using electronic health record data, we identified family members (n=201,914) of adult index patients (n=92,399) diagnosed with MDD between 2009 and 2014 and family members (n=187,011) of matched patients without MDD. Diagnoses, health care utilization and costs were extracted for each family member. Logistic regression and multivariate models were used to compare diagnosed health conditions, health services cost, and utilization of MDD and non-MDD family members. Analyses covered the 5years before and after the index patient's MDD diagnosis. MDD family members were more likely than non-MDD family members to be diagnosed with mood disorders, anxiety, substance use disorder, and numerous other conditions. MDD family members had higher health care costs than non-MDD family members in every period analyzed, with the highest difference being in the year before the index patient's MDD diagnosis. Family members of patients with MDD are more likely to have a number of health conditions compared to non-MDD family members, and to have higher health care cost and utilization. Copyright © 2017. Published by Elsevier Inc.

  20. Evaluation of the Space and Naval Warfare Systems Command (SPAWAR) Cost and Performance Measurement

    OpenAIRE

    Flavell, Drew G.; Dorwin, Timothy E.

    1999-01-01

    Approved for public release; distribution is unlimited. This thesis examines the Cost and Performance Measurements within four Program Directorates at the Space and Naval Warfare Systems Command (SPAWAR). SPAWAR is the Navy's full-spectrum research, development, test and evaluation, engineering and fleet support center for Command, Control and Communications Systems, Ocean Surveillance Systems and the integration of those systems that overarch multiplatforms. In the era of lean military bu...

  1. Thermal convection in a closed cavity in zero-gravity space conditions with stationary magnetic forces

    International Nuclear Information System (INIS)

    Lyubimova, T; Mailfert, A

    2013-01-01

    The paper deals with the investigation of thermo-magnetic convection in a paramagnetic liquid subjected to a non-uniform magnetic field in weightlessness conditions. Indeed, in zero-g space conditions such as realized in International Space Station (ISS), or in artificial satellite, or in free-flight space vessels, the classical thermo-gravitational convection in fluid disappears. In any cases, it may be useful to restore the convective thermal exchange inside fluids such as liquid oxygen. In this paper, the restoration of heat exchange by the way of creation of magnetic convection is numerically studied.

  2. Orion: Design of a system for assured low-cost human access to space

    Science.gov (United States)

    Elvander, Josh; Heifetz, Andy; Hunt, Teresa; Zhu, Martin

    1994-01-01

    In recent years, Congress and the American people have begun to seriously question the role and importance of future manned spaceflight. This is mainly due to two factors: a decline in technical competition caused by the collapse of communism, and the high costs associated with the Space Shuttle transportation system. With these factors in mind, the ORION system was designed to enable manned spaceflight at a low cost, while maintaining the ability to carry out diverse missions, each with a high degree of flexibility. It is capable of performing satellite servicing missions, supporting a space station via crew rotation and resupply, and delivering satellites into geosynchronous orbit. The components of the system are a primary launch module, an upper stage, and a manned spacecraft capable of dynamic reentry. For satellite servicing and space station resupply missions, the ORION system utilizes three primary modules, an upper stage, and the spacecraft, which is delivered to low earth orbit and used to rendezvous, transfer materials, and make repairs. For launching a geosynchronous satellite, one primary module and an upper stage are used to deliver the satellite, along with an apogee kick motor, into orbit. The system is designed with reusability and modularity in mind in an attempt to lower cost.

  3. Modern education of future teacher of physical culture in the conditions of informatization of educational space

    Directory of Open Access Journals (Sweden)

    Dragnev Y.V.

    2012-03-01

    Full Text Available The informatization of the educational space is determined by the organizational, scientific-technical, educational processes, which update the creation of the unified information and educational space for the comprehensive use of information technologies in educational process of a future teacher of physical culture at the higher school. Stated that the integration and expansion of the educational space of the orients the higher school not only in the preparation of the literate student on the issues of information culture, but also to help the younger generation in the mastery of basic social abilities and skills in conditions of informatization of the educational space.

  4. S-Denying of the Signature Conditions Expands General Relativity's Space

    Directory of Open Access Journals (Sweden)

    Rabounski D.

    2006-07-01

    Full Text Available We apply the S-denying procedure to signature conditions in a four-dimensional pseudo-Riemannian space — i. e. we change one (or even all of the conditions to be partially true and partially false. We obtain five kinds of expanded space-time for General Relativity. Kind I permits the space-time to be in collapse. Kind II permits the space-time to change its own signature. Kind III has peculiarities, linked to the third signature condition. Kind IV permits regions where the metric fully degenerates: there may be non-quantum teleportation, and a home for virtual photons. Kind V is common for kinds I, II, III, and IV.

  5. Prime focus architectures for large space telescopes: reduce surfaces to save cost

    Science.gov (United States)

    Breckinridge, J. B.; Lillie, C. F.

    2016-07-01

    Conceptual architectures are now being developed to identify future directions for post JWST large space telescope systems to operate in the UV Optical and near IR regions of the spectrum. Here we show that the cost of optical surfaces within large aperture telescope/instrument systems can exceed $100M/reflection when expressed in terms of the aperture increase needed to over come internal absorption loss. We recommend a program in innovative optical design to minimize the number of surfaces by considering multiple functions for mirrors. An example is given using the Rowland circle imaging spectrometer systems for UV space science. With few exceptions, current space telescope architectures are based on systems optimized for ground-based astronomy. Both HST and JWST are classical "Cassegrain" telescopes derived from the ground-based tradition to co-locate the massive primary mirror and the instruments at the same end of the metrology structure. This requirement derives from the dual need to minimize observatory dome size and cost in the presence of the Earth's 1-g gravitational field. Space telescopes, however function in the zero gravity of space and the 1- g constraint is relieved to the advantage of astronomers. Here we suggest that a prime focus large aperture telescope system in space may have potentially have higher transmittance, better pointing, improved thermal and structural control, less internal polarization and broader wavelength coverage than Cassegrain telescopes. An example is given showing how UV astronomy telescopes use single optical elements for multiple functions and therefore have a minimum number of reflections.

  6. Factors associated with geographic variation in cost per episode of care for three medical conditions

    Science.gov (United States)

    2014-01-01

    Objective To identify associations between market factors, especially relative reimbursement rates, and the probability of surgery and cost per episode for three medical conditions (cataract, benign prostatic neoplasm, and knee degeneration) with multiple treatment options. Methods We use 2004–2006 Medicare claims data for elderly beneficiaries from sixty nationally representative communities to estimate multivariate models for the probability of surgery and cost per episode of care as a function local market factors, including Medicare physician reimbursement for surgical versus non-surgical treatment and the availability of primary care and specialty physicians. We used Symmetry’s Episode Treatment Groups (ETG) software to group claims into episodes for the three conditions (n = 540,874 episodes). Results Higher Medicare reimbursement for surgical episodes and greater availability of the relevant specialists are significantly associated with more surgery and higher cost per episode for all three conditions, while greater availability of primary care physicians is significantly associated with less frequent surgery and lower cost per episode. Conclusion Relative Medicare reimbursement rates for surgical vs. non-surgical treatments and the availability of both primary care physicians and relevant specialists are associated with the likelihood of surgery and cost per episode. PMID:24949281

  7. Life cycle cost analysis of HPVT air collector under different Indian climatic conditions

    International Nuclear Information System (INIS)

    Raman, Vivek; Tiwari, G.N.

    2008-01-01

    In this communication, a study is carried out to evaluate an annual thermal and exergy efficiency of a hybrid photovoltaic thermal (HPVT) air collector for different Indian climate conditions, of Srinagar, Mumbai, Jodhpur, New Delhi and Banglore. The study has been based on electrical, thermal and exergy output of the HPVT air collector. Further, the life cycle analysis in terms of cost/kWh has been carried out. The main focus of the study is to see the effect of interest rate, life of the HPVT air collector, subsidy, etc. on the cost/kWh HPVT air collector. A comparison is made keeping in view the energy matrices. The study reveals that (i) annual thermal and electrical efficiency decreases with increase in solar radiation and (ii) the cost/kWh is higher in case of exergy when compared with cost/kWh on the basis of thermal energy for all climate conditions. The cost/kWh for climate conditions of Jodhpur is most economical

  8. Probabilistic prediction of expected ground condition and construction time and costs in road tunnels

    Directory of Open Access Journals (Sweden)

    A. Mahmoodzadeh

    2016-10-01

    Full Text Available Ground condition and construction (excavation and support time and costs are the key factors in decision-making during planning and design phases of a tunnel project. An innovative methodology for probabilistic estimation of ground condition and construction time and costs is proposed, which is an integration of the ground prediction approach based on Markov process, and the time and cost variance analysis based on Monte-Carlo (MC simulation. The former provides the probabilistic description of ground classification along tunnel alignment according to the geological information revealed from geological profile and boreholes. The latter provides the probabilistic description of the expected construction time and costs for each operation according to the survey feedbacks from experts. Then an engineering application to Hamro tunnel is presented to demonstrate how the ground condition and the construction time and costs are estimated in a probabilistic way. In most items, in order to estimate the data needed for this methodology, a number of questionnaires are distributed among the tunneling experts and finally the mean values of the respondents are applied. These facilitate both the owners and the contractors to be aware of the risk that they should carry before construction, and are useful for both tendering and bidding.

  9. Estimation of Radiation Limit from a Huygens' Box under Non-Free-Space Conditions

    DEFF Research Database (Denmark)

    Franek, Ondrej; Sørensen, Morten; Bonev, Ivan Bonev

    2013-01-01

    The recently studied Huygens' box method has difficulties when radiation of an electronic module is to be determined under non-free-space conditions, i.e. with an enclosure. We propose an estimate on radiation limit under such conditions based only on the Huygens' box data from free...

  10. The in vitro fitness cost of antimicrobial resistance in Escherichia coli varies with the growth conditions

    DEFF Research Database (Denmark)

    Petersen, Andreas; Aarestrup, Frank Møller; Olsen, John Elmerdahl

    2009-01-01

    The objective of this study was to investigate the influence of stressful growth conditions on the fitness cost of antimicrobial resistance in Escherichia coli BJ4 caused by chromosomal mutations and plasmid acquisition. The fitness cost of chromosomal streptomycin resistance increased......H and at high-salt concentrations. Strains with an impaired rpoS demonstrated a reduced fitness only during growth in a high-salt concentration. In conclusion, it was demonstrated that bacterial fitness cost in association with antimicrobial resistance generally increases under stressful growth conditions....... However, the growth potential of bacteria with antimicrobial resistances did not increase in a straightforward manner in these in vitro experiments and is therefore probably even more difficult to predict in vivo....

  11. Cost-Effective Shaft Torque Observer for Condition Monitoring of Wind Turbines

    DEFF Research Database (Denmark)

    Perisic, Nevena; Kirkegaard, Poul Henning; Pedersen, Bo Juul

    2015-01-01

    Improvement of condition monitoring (CM) systems for wind turbines (WTs) and reduction of the cost of wind energy are possible if knowledge about the condition of different WT components is available. CM based on the WT drive train shaft torque signal can give a better understanding of the gearbox...... of the augmented Kalman filter with fading memory (AKFF) is compared with the augmented Kalman filter (AKF) using simulated data of theWT for different load conditions, measurement noise levels andWT fault scenarios. A multiple-model algorithm, based on a set of different Kalman filters, is designed for practical...

  12. The Solar Umbrella: A Low-cost Demonstration of Scalable Space Based Solar Power

    Science.gov (United States)

    Contreras, Michael T.; Trease, Brian P.; Sherwood, Brent

    2013-01-01

    Within the past decade, the Space Solar Power (SSP) community has seen an influx of stakeholders willing to entertain the SSP prospect of potentially boundless, base-load solar energy. Interested parties affiliated with the Department of Defense (DoD), the private sector, and various international entities have all agreed that while the benefits of SSP are tremendous and potentially profitable, the risk associated with developing an efficient end to end SSP harvesting system is still very high. In an effort to reduce the implementation risk for future SSP architectures, this study proposes a system level design that is both low-cost and seeks to demonstrate the furthest transmission of wireless power to date. The overall concept is presented and each subsystem is explained in detail with best estimates of current implementable technologies. Basic cost models were constructed based on input from JPL subject matter experts and assume that the technology demonstration would be carried out by a federally funded entity. The main thrust of the architecture is to demonstrate that a usable amount of solar power can be safely and reliably transmitted from space to the Earth's surface; however, maximum power scalability limits and their cost implications are discussed.

  13. Bridge Management Strategy Based on Extreme User Costs for Bridge Network Condition

    Directory of Open Access Journals (Sweden)

    Ladislaus Lwambuka

    2014-01-01

    Full Text Available This paper presents a practical approach for prioritization of bridge maintenance within a given bridge network. The maintenance prioritization is formulated as a multiobjective optimization problem where the simultaneous satisfaction of several conflicting objectives includes minimization of maintenance costs, maximization of bridge deck condition, and minimization of traffic disruption and associated user costs. The prevalence of user cost during maintenance period is twofold; the first case refers to the period of dry season where normally the traffic flow is diverted to alternative routes usually resurfaced to regain traffic access. The second prevalence refers to the absence of alternative routes which is often the case in the least developed countries; in this case the user cost referred to results from the waiting time while the traffic flow is put on hold awaiting accomplishment of the maintenance activity. This paper deals with the second scenario of traffic closure in the absence of alternative diversion routes which in essence results in extreme user cost. The paper shows that the multiobjective optimization approach remains valid for extreme cases of user costs in the absence of detour roads as often is the scenario in countries with extreme poor road infrastructure.

  14. Solar chimney: A sustainable approach for ventilation and building space conditioning

    Directory of Open Access Journals (Sweden)

    Lal, S.,

    2013-03-01

    Full Text Available The residential and commercial buildings demand increase with rapidly growing population. It leads to the vertical growth of the buildings and needs proper ventilation and day-lighting. The natural air ventilation system is not significantly works in conventional structure, so fans and air conditioners are mandatory to meet the proper ventilation and space conditioning. Globally building sector consumed largest energy and utmost consumed in heating, ventilation and space conditioning. This load can be reduced by application of solar chimney and integrated approaches in buildings for heating, ventilation and space conditioning. It is a sustainable approach for these applications in buildings. The authors are reviewed the concept, various method of evaluation, modelings and performance of solar chimney variables, applications and integrated approaches.

  15. Common fixed point theorems in intuitionistic fuzzy metric spaces and L-fuzzy metric spaces with nonlinear contractive condition

    International Nuclear Information System (INIS)

    Jesic, Sinisa N.; Babacev, Natasa A.

    2008-01-01

    The purpose of this paper is to prove some common fixed point theorems for a pair of R-weakly commuting mappings defined on intuitionistic fuzzy metric spaces [Park JH. Intuitionistic fuzzy metric spaces. Chaos, Solitons and Fractals 2004;22:1039-46] and L-fuzzy metric spaces [Saadati R, Razani A, Adibi H. A common fixed point theorem in L-fuzzy metric spaces. Chaos, Solitons and Fractals, doi:10.1016/j.chaos.2006.01.023], with nonlinear contractive condition, defined with function, first observed by Boyd and Wong [Boyd DW, Wong JSW. On nonlinear contractions. Proc Am Math Soc 1969;20:458-64]. Following Pant [Pant RP. Common fixed points of noncommuting mappings. J Math Anal Appl 1994;188:436-40] we define R-weak commutativity for a pair of mappings and then prove the main results. These results generalize some known results due to Saadati et al., and Jungck [Jungck G. Commuting maps and fixed points. Am Math Mon 1976;83:261-3]. Some examples and comments according to the preceding results are given

  16. Space Infrared Telescope Facility (SIRTF) - Operations concept. [decreasing development and operations cost

    Science.gov (United States)

    Miller, Richard B.

    1992-01-01

    The development and operations costs of the Space IR Telescope Facility (SIRTF) are discussed in the light of minimizing total outlays and optimizing efficiency. The development phase cannot extend into the post-launch segment which is planned to only support system verification and calibration followed by operations with a 70-percent efficiency goal. The importance of reducing the ground-support staff is demonstrated, and the value of the highly sensitive observations to the general astronomical community is described. The Failure Protection Algorithm for the SIRTF is designed for the 5-yr lifetime and the continuous venting of cryogen, and a science driven ground/operations system is described. Attention is given to balancing cost and performance, prototyping during the development phase, incremental development, the utilization of standards, and the integration of ground system/operations with flight system integration and test.

  17. Cost-Effective Additive Manufacturing in Space: HELIOS Technology Challenge Guide

    Science.gov (United States)

    DeVieneni, Alayna; Velez, Carlos Andres; Benjamin, David; Hollenbeck, Jay

    2012-01-01

    Welcome to the HELIOS Technology Challenge Guide. This document is intended to serve as a general road map for participants of the HELIOS Technology Challenge [HTC] Program and the associated inaugural challenge: HTC-01: Cost-Effective Additive Manufacturing in Space. Please note that this guide is not a rule book and is not meant to hinder the development of innovative ideas. Its primary goal is to highlight the objectives of the HTC-01 Challenge and to describe possible solution routes and pitfalls that such technology may encounter in space. Please also note that participants wishing to demonstrate any hardware developed under this program during any future HELIOS Technology Challenge showcase event(s) may be subject to event regulations to be published separately at a later date.

  18. The Influence of Pre-Conditioning on Space Charge Formation in LDPE

    DEFF Research Database (Denmark)

    Fleming, Robert J.; Henriksen, Mogens; Holbøll, Joachim T.

    1996-01-01

    In this paper we present space charge accumulation data for planar low density polyethylene samples subjected to 20 kV/mm dc fields at room temperature. The data were obtained using the laser-induced-pressure-pulse (LIPP) technique. Some of the samples were conditioned by holding them at 40oC in ......C in short-circuit at rotary pump pressure for 48 hr prior to measurement. Such conditioning had no consistent effect on the space charge. The extent of charge injection/extraction at the semicon electrodes appeared to vary considerably between samples....

  19. Evaluation of comfort conditions in urban open spaces. Application in the island of Crete

    International Nuclear Information System (INIS)

    Tsitoura, Marianna; Tsoutsos, Theocharis; Daras, Tryfon

    2014-01-01

    Highlights: • Outdoor spaces field surveys carried out in four different urban open spaces. • A strong connection between the microclimate and the use of open space. • Human physical and psychological factors can optimize the urban space design. - Abstract: The thermal environment in outdoor public spaces and their level of use are strongly connected. The design of outdoor spaces, especially in urban areas, is very critical in Southern Europe due to their extended use during summertime where the urban heat island phenomenon deteriorates the microclimatic conditions. In this paper the main outcomes of outdoor spaces field surveys are presented, which were carried out in four different urban open spaces in Crete. On site measurements were implemented and a questionnaire was used in order to estimate the thermal comfort of visitors. Thermal indices like Predicted Mean Vote, Physiologically Equivalent Temperature, Standard Effective Temperature, Wet Bulb Globe Temperature are used to evaluate the features of urban microclimate and then are being compared in order to find the most suitable for the Mediterranean microclimate. This suggests another way of approach to the researcher and provides essential tools to the designer

  20. Systematic mapping review about costs and economic evaluations of skin conditions and diseases in the aged.

    Science.gov (United States)

    Lichterfeld-Kottner, Andrea; Hahnel, Elisabeth; Blume-Peytavi, Ulrike; Kottner, Jan

    2017-02-01

    Skin conditions and dermatological diseases associated with advanced age (e.g. fungal infection, dry skin and itch) receive increasingly attention in clinical practice and research. Cost and economic evaluations are important sources to inform priority setting and ressource allocation decisions in healthcare. The economics of skin conditions in aged populations has not been systematically reviewed so far. The aim of this mapping review was to summarize the economic evidence of selected skin conditions in the aged (65 + years). A mapping literature review and evidence summary was conducted. Searches were conducted in data bases Medline and Embase via OVID. Cinahl was searched using EBSCO. References lists of potential eligible studies, reviews, guidelines or other sources were screened for additional literature. For evaluation of methodological quality of full economic analyses the Consensus on Health Economic Criteria (CHEC) checklist was used. Database searches resulted in 1388 records. A total of 270 articles were read in full-text. Thirty-five publications were finally included in the data analysis reporting 38 economic analyses. Ten cost of illness analyses and 26 cost-effectiveness analyses reporting about pressure ulcers, skin tears, pressure ulcers, incontinence associated dermatitis and intertrigo/contact dermatitis/candidiasis treatment and prevention and onychomycosis testing were identified. Limited evidence indicated that low air loss beds were more cost effective than standard beds for prevention of pressure ulcers. Standardized skin care regimens seem to lower the incidence of pressure ulcers, skin tears and IAD but a cost saving effect was not always observed. Findings of this mapping review indicate that there is a paucity of high quality evidence regarding the economic impact of age-associated skin conditions and diseases. Substantial heterogeneity in terms of study design, evaluation perspective, time period, and way of cost estimation was

  1. Decreasing the cost of ground grid installations under difficult environmental conditions

    International Nuclear Information System (INIS)

    Miranda, E.P.

    1992-01-01

    The purpose of a ground grid is to provide a means to carry and dissipate electrical currents into ground under normal and fault conditions. In some cases, especially in dry rock terrain, the soil resistivity can be very high, making it difficult and very expensive to install an acceptable ground grid. Usually a soil resistivity above 200 ohm-meter is considered high. This paper discusses and provides design calculations for a successful ground grid installation in a distribution substation located in one of the worst soil conditions encountered in the industry; a very rocky terrain where the resistivity is 1800 ohm-m. It is a practical application of the theories presented in ANSI/IEEE Std. 80-1986. The design application consists of bare copper combined with conventional and a new type of ground rod. The installation cost for this application was much less than the cost associated with that of a conventional installation

  2. Cost-Effective ISS Space-Environment Technology Validation of Advanced Roll-Out Solar Array (ROSA), Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — DSS proposes to systematically mature, mitigate risk for; and perform hardware-based ground validations / demonstrations of a low-cost, high technology payoff,...

  3. Risk-Sensitive Control of Pure Jump Process on Countable Space with Near Monotone Cost

    International Nuclear Information System (INIS)

    Suresh Kumar, K.; Pal, Chandan

    2013-01-01

    In this article, we study risk-sensitive control problem with controlled continuous time pure jump process on a countable space as state dynamics. We prove multiplicative dynamic programming principle, elliptic and parabolic Harnack’s inequalities. Using the multiplicative dynamic programing principle and the Harnack’s inequalities, we prove the existence and a characterization of optimal risk-sensitive control under the near monotone condition

  4. Investigating the environmental costs of deteriorating road conditions in South Africa

    CSIR Research Space (South Africa)

    Mashoko, L

    2014-07-01

    Full Text Available the Environmental Costs of Deteriorating Road Conditions in South Africa L Mashoko, W L Bean*, W JvdM STEYN* CSIR, Built Environment, P O Box 395, Pretoria, 0001 Tel: 012 841-4466; Email: lmashoko@csir.co.za *University of Pretoria, Lynnwood Road, Hatfield..., Pretoria, 0002 Email: wilna.bean@up.ac.za and wynand.steyn@up.ac.za Corresponding Author: L Mashoko ABSTRACT The potential environmental impacts of deteriorating road conditions on logistics systems and the national economy have not received...

  5. Renewed growth in hospital inpatient cost since 1998: variation across metropolitan areas and leading clinical conditions.

    Science.gov (United States)

    Friedman, Bernard S; Wong, Herbert S; Steiner, Claudia A

    2006-03-01

    To use disaggregated data about metropolitan statistical areas (MSAs) and clinical conditions to better describe the variation in cost increases and explore some of the hypothesized influences. The study uses the state inpatient databases from the Healthcare Cost and Utilization Project, containing all discharges from hospitals in 172 MSAs in 1998 and 2001. The discharge summary information was combined with standardized hospital accounting files, surveys of managed care plans, MSA demographics, and state data pertaining to caps on medical malpractice awards. The analysis used descriptive comparisons and multivariate regressions of admission rate and cost per case in 9 leading disease categories across the MSAs. The increase in hospital input prices and changes in severity of illness were controlled. Metropolitan statistical areas with higher HMO market penetration continued to show lower admission rates, no less so in 2001 than in 1998. A cap on malpractice awards appeared to restrain admissions, but the net effect on hospital cost per adult eroded for those states with the most experience with award caps. Higher admission rates and increase in cost were found in several disease categories.

  6. Experimental verification of free-space singular boundary conditions in an invisibility cloak

    International Nuclear Information System (INIS)

    Wu, Qiannan; Gao, Fei; Song, Zhengyong; Lin, Xiao; Zhang, Youming; Zhang, Baile; Chen, Huanyang

    2016-01-01

    A major issue in invisibility cloaking, which caused intense mathematical discussions in the past few years but still remains physically elusive, is the plausible singular boundary conditions associated with the singular metamaterials at the inner boundary of an invisibility cloak. The perfect cloaking phenomenon, as originally proposed by Pendry et al for electromagnetic waves, cannot be treated as physical before a realistic inner boundary of a cloak is demonstrated. Although a recent demonstration has been done in a waveguide environment, the exotic singular boundary conditions should apply to a general environment as in free space. Here we fabricate a metamaterial surface that exhibits the singular boundary conditions and demonstrate its performance in free space. Particularly, the phase information of waves reflected from this metamaterial surface is explicitly measured, confirming the singular responses of boundary conditions for an invisibility cloak. (paper)

  7. Experimental verification of free-space singular boundary conditions in an invisibility cloak

    Science.gov (United States)

    Wu, Qiannan; Gao, Fei; Song, Zhengyong; Lin, Xiao; Zhang, Youming; Chen, Huanyang; Zhang, Baile

    2016-04-01

    A major issue in invisibility cloaking, which caused intense mathematical discussions in the past few years but still remains physically elusive, is the plausible singular boundary conditions associated with the singular metamaterials at the inner boundary of an invisibility cloak. The perfect cloaking phenomenon, as originally proposed by Pendry et al for electromagnetic waves, cannot be treated as physical before a realistic inner boundary of a cloak is demonstrated. Although a recent demonstration has been done in a waveguide environment, the exotic singular boundary conditions should apply to a general environment as in free space. Here we fabricate a metamaterial surface that exhibits the singular boundary conditions and demonstrate its performance in free space. Particularly, the phase information of waves reflected from this metamaterial surface is explicitly measured, confirming the singular responses of boundary conditions for an invisibility cloak.

  8. Surgical Space Conditions During Low-Pressure Laparoscopic Cholecystectomy with Deep Versus Moderate Neuromuscular Blockade

    DEFF Research Database (Denmark)

    Staehr-Rye, Anne K; Rasmussen, Lars S.; Rosenberg, Jacob

    2014-01-01

    : In this assessor-blinded study, 48 patients undergoing elective laparoscopic cholecystectomy were administered rocuronium for neuromuscular blockade and randomized to either deep neuromuscular blockade (rocuronium bolus plus infusion maintaining a posttetanic count 0-1) or moderate neuromuscular blockade...... (rocuronium repeat bolus only for inadequate surgical conditions with spontaneous recovery of neuromuscular function). Patients received anesthesia with propofol, remifentanil, and rocuronium. The primary outcome was the proportion of procedures with optimal surgical space conditions (assessed by the surgeon...

  9. An alternative phase-space distribution to sample initial conditions for classical dynamics simulations

    International Nuclear Information System (INIS)

    Garcia-Vela, A.

    2002-01-01

    A new quantum-type phase-space distribution is proposed in order to sample initial conditions for classical trajectory simulations. The phase-space distribution is obtained as the modulus of a quantum phase-space state of the system, defined as the direct product of the coordinate and momentum representations of the quantum initial state. The distribution is tested by sampling initial conditions which reproduce the initial state of the Ar-HCl cluster prepared by ultraviolet excitation, and by simulating the photodissociation dynamics by classical trajectories. The results are compared with those of a wave packet calculation, and with a classical simulation using an initial phase-space distribution recently suggested. A better agreement is found between the classical and the quantum predictions with the present phase-space distribution, as compared with the previous one. This improvement is attributed to the fact that the phase-space distribution propagated classically in this work resembles more closely the shape of the wave packet propagated quantum mechanically

  10. Impact of a hospitalist system on length of stay and cost for children with common conditions.

    Science.gov (United States)

    Srivastava, Rajendu; Landrigan, Christopher P; Ross-Degnan, Dennis; Soumerai, Stephen B; Homer, Charles J; Goldmann, Donald A; Muret-Wagstaff, Sharon

    2007-08-01

    This study examined mechanisms of efficiency in a managed care hospitalist system on length of stay and total costs for common pediatric conditions. We conducted a retrospective cohort study (October 1993 to July 1998) of patients in a not-for-profit staff model (HMO 1) and a non-staff-model (HMO 2) managed care organization at a freestanding children's hospital. HMO 1 introduced a hospitalist system for patients in October 1996. Patients were included if they had 1 of 3 common diagnoses: asthma, dehydration, or viral illness. Linear regression models examining length-of-stay-specific costs for prehospitalist and posthospitalist systems were built. Distribution of length of stay for each diagnosis before and after the system change in both study groups was calculated. Interrupted time series analysis tested whether changes in the trends of length of stay and total costs occurred after implementation of the hospitalist system by HMO1 (HMO 2 as comparison group) for all 3 diagnoses combined. A total of 1970 patients with 1 of the 3 study conditions were cared for in HMO 1, and 1001 in HMO 2. After the hospitalist system was introduced in HMO 1, length of stay was reduced by 0.23 days (13%) for asthma and 0.19 days (11%) for dehydration; there was no difference for patients with viral illness. The largest relative reduction in length of stay occurred in patients with a shorter length of stay whose hospitalizations were reduced from 2 days to 1 day. This shift resulted in an average cost-per-case reduction of $105.51 (9.3%) for patients with asthma and $86.22 (7.8%) for patients with dehydration. During the same period, length of stay and total cost rose in HMO 2. Introduction of a hospitalist system in one health maintenance organization resulted in earlier discharges and reduced costs for children with asthma and dehydration compared with another one, with the largest reductions occurring in reducing some 2-day hospitalizations to 1 day. These findings suggest that

  11. Manufacturing of Low Cost, Durable Membrane Electrode Assemblies Engineered for Rapid Conditioning

    Energy Technology Data Exchange (ETDEWEB)

    Busby, Colin [W. L. Gore & Associates Inc., Newark, DE (United States)

    2017-05-23

    Over the past 20 years significant progress in membrane-electrode assembly (MEA) technology development for polymer electrolyte fuel cells (PEMFCs) has resulted in the PEMFC technology approaching a commercial reality for transportation applications. However, there remain two primary technical challenges to be addressed in the MEA. First and foremost is meeting the automotive cost targets: Producing a fuel cell stack cost competitive with today’s internal combustion engine. In addition to the material cost, MEA (and other components) and stack assembly production methods must be amenable for use in low cost, high speed, automotive assembly line. One impediment to this latter goal is that stack components must currently go through a long and tedious conditioning procedure before they produce optimal power. This so-called “break-in” can take many hours, and can involve quite complex voltage, temperature and/or pressure steps. These break-in procedures must be simplified and the time required reduced if fuel cells are to become a viable automotive engine. The second challenge is to achieve the durability targets in real-world automotive duty cycle operations. Significant improvements in cost, break-in time, and durability for the key component of fuel cell stacks, MEAs were achieved in this project. Advanced modeling was used to guide design of the new MEA to maximize performance and durability. A new, innovative process and manufacturing approach utilizing direct in-line coating using scalable, cost-competitive, continuous high volume 3-layer rolled-good manufacturing processes was developed and validated by single cell and short stack testing. In addition, the direct coating methods employed were shown to reduce the cost for sacrificial films. Furthermore, Gore has demonstrated a 10 µm reinforced membrane that is used in the new low-cost process and can meet automotive power density and durability targets. Across a wide range of operating conditions, the

  12. A Coupled Fixed Point Theorem in Fuzzy Metric Space Satisfying ϕ-Contractive Condition

    Directory of Open Access Journals (Sweden)

    B. D. Pant

    2013-01-01

    Full Text Available The intent of this paper is to prove a coupled fixed point theorem for two pairs of compatible and subsequentially continuous (alternately subcompatible and reciprocally continuous mappings, satisfying ϕ-contractive conditions in a fuzzy metric space. We also furnish some illustrative examples to support our results.

  13. On a nonlinear integrodifferential evolution inclusion with nonlocal initial conditions in Banach spaces

    Directory of Open Access Journals (Sweden)

    Zuomao Yan

    2012-01-01

    Full Text Available In this paper, we discuss the existence results for a class of nnlinear integrodifferential evolution inclusions with nonlocal initial conditions in Banach spaces. Our results are based on a fixed point theorem for condensing maps due to Martelli and the resolvent operators combined with approximation techniques.

  14. The Influence of Pre-conditioning on the Space Charge Formation in LDPE and XLPE

    DEFF Research Database (Denmark)

    Henriksen, Mogens; Holbøll, Joachim T.; Fleming, R.J.

    1996-01-01

    Planar LDPE and XLPE samples were conditioned by holding in short circuit for 48 hrs. at 40oC under rotary pump pressure, and space charge accumulation in these samples under DC fields of 20 kV/mm was then compared with the corresponding accumulation in unconditioned samples.The test results were...

  15. Results from the NASA Spacecraft Fault Management Workshop: Cost Drivers for Deep Space Missions

    Science.gov (United States)

    Newhouse, Marilyn E.; McDougal, John; Barley, Bryan; Stephens Karen; Fesq, Lorraine M.

    2010-01-01

    Fault Management, the detection of and response to in-flight anomalies, is a critical aspect of deep-space missions. Fault management capabilities are commonly distributed across flight and ground subsystems, impacting hardware, software, and mission operations designs. The National Aeronautics and Space Administration (NASA) Discovery & New Frontiers (D&NF) Program Office at Marshall Space Flight Center (MSFC) recently studied cost overruns and schedule delays for five missions. The goal was to identify the underlying causes for the overruns and delays, and to develop practical mitigations to assist the D&NF projects in identifying potential risks and controlling the associated impacts to proposed mission costs and schedules. The study found that four out of the five missions studied had significant overruns due to underestimating the complexity and support requirements for fault management. As a result of this and other recent experiences, the NASA Science Mission Directorate (SMD) Planetary Science Division (PSD) commissioned a workshop to bring together invited participants across government, industry, and academia to assess the state of the art in fault management practice and research, identify current and potential issues, and make recommendations for addressing these issues. The workshop was held in New Orleans in April of 2008. The workshop concluded that fault management is not being limited by technology, but rather by a lack of emphasis and discipline in both the engineering and programmatic dimensions. Some of the areas cited in the findings include different, conflicting, and changing institutional goals and risk postures; unclear ownership of end-to-end fault management engineering; inadequate understanding of the impact of mission-level requirements on fault management complexity; and practices, processes, and tools that have not kept pace with the increasing complexity of mission requirements and spacecraft systems. This paper summarizes the

  16. Integrating Efficiency of Industry Processes and Practices Alongside Technology Effectiveness in Space Transportation Cost Modeling and Analysis

    Science.gov (United States)

    Zapata, Edgar

    2012-01-01

    This paper presents past and current work in dealing with indirect industry and NASA costs when providing cost estimation or analysis for NASA projects and programs. Indirect costs, when defined as those costs in a project removed from the actual hardware or software hands-on labor; makes up most of the costs of today's complex large scale NASA space/industry projects. This appears to be the case across phases from research into development into production and into the operation of the system. Space transportation is the case of interest here. Modeling and cost estimation as a process rather than a product will be emphasized. Analysis as a series of belief systems in play among decision makers and decision factors will also be emphasized to provide context.

  17. Collaborative testing for key-term definitions under representative conditions: Efficiency costs and no learning benefits.

    Science.gov (United States)

    Wissman, Kathryn T; Rawson, Katherine A

    2018-01-01

    Students are expected to learn key-term definitions across many different grade levels and academic disciplines. Thus, investigating ways to promote understanding of key-term definitions is of critical importance for applied purposes. A recent survey showed that learners report engaging in collaborative practice testing when learning key-term definitions, with outcomes also shedding light on the way in which learners report engaging in collaborative testing in real-world contexts (Wissman & Rawson, 2016, Memory, 24, 223-239). However, no research has directly explored the effectiveness of engaging in collaborative testing under representative conditions. Accordingly, the current research evaluates the costs (with respect to efficiency) and the benefits (with respect to learning) of collaborative testing for key-term definitions under representative conditions. In three experiments (ns = 94, 74, 95), learners individually studied key-term definitions and then completed retrieval practice, which occurred either individually or collaboratively (in dyads). Two days later, all learners completed a final individual test. Results from Experiments 1-2 showed a cost (with respect to efficiency) and no benefit (with respect to learning) of engaging in collaborative testing for key-term definitions. Experiment 3 evaluated a theoretical explanation for why collaborative benefits do not emerge under representative conditions. Collectively, outcomes indicate that collaborative testing versus individual testing is less effective and less efficient when learning key-term definitions under representative conditions.

  18. Dimension elevation in Müntz spaces: A new emergence of the Müntz condition

    KAUST Repository

    Ait-Haddou, Rachid

    2014-05-01

    We show that the limiting polygon generated by the dimension elevation algorithm with respect to the Müntz space span(1,tr1,tr2,trm,. . .), with 0 < r1 < r2 < ⋯ < r m < ⋯ and lim n →∞r n = ∞, over an interval [a, b] ⊂ ] 0, ∞ [ converges to the underlying Chebyshev-Bézier curve if and only if the Müntz condition ∑i=1∞1ri=∞ is satisfied. The surprising emergence of the Müntz condition in the problem raises the question of a possible connection between the density questions of nested Chebyshev spaces and the convergence of the corresponding dimension elevation algorithms. The question of convergence with no condition of monotonicity or positivity on the pairwise distinct real numbers r i remains an open problem. © 2014 Elsevier Inc.

  19. Obstetric Outcomes and Delivery-Related Health Care Utilization and Costs Among Pregnant Women With Multiple Chronic Conditions

    Science.gov (United States)

    Winkelman, Tyler N. A.; Heisler, Michele; Dalton, Vanessa K.

    2018-01-01

    Our objective was to measure obstetric outcomes and delivery-related health care utilization and costs among pregnant women with multiple chronic conditions. We used 2013–2014 data from the National Inpatient Sample to measure obstetric outcomes and delivery-related health care utilization and costs among women with no chronic conditions, 1 chronic condition, and multiple chronic conditions. Women with multiple chronic conditions were at significantly higher risk than women with 1 chronic condition or no chronic conditions across all outcomes measured. High-value strategies are needed to improve birth outcomes among vulnerable mothers and their infants. PMID:29420168

  20. Origin of how steam rockets can reduce space transport cost by orders of magnitude

    International Nuclear Information System (INIS)

    Zuppero, A.; Larson, T.K.; Schnitzler, B.G.; Rice, J.W.; Hill, T.J.; Richins, W.D.; Parlier, L.; Werner, J.E.

    1999-01-01

    A brief sketch shows the origin of why and how thermal rocket propulsion has the unique potential to dramatically reduce the cost of space transportation for most inner solar system missions of interest. Orders of magnitude reduction in cost are apparently possible when compared to all processes requiring electrolysis for the production of rocket fuels or propellants and to all electric propulsion systems. An order of magnitude advantage can be attributed to rocket propellant tank factors associated with storing water propellant, compared to cryogenic liquids. An order of magnitude can also be attributed to the simplicity of the extraction and processing of ice on the lunar surface, into an easily stored, non-cryogenic rocket propellant (water). A nuclear heated thermal rocket can deliver thousands of times its mass to Low Earth Orbit from the Lunar surface, providing the equivalent to orders of magnitude drop in launch cost for mass in Earth orbit. Mass includes water ice. These cost reductions depend (exponentially) on the mission delta-v requirements being less than about 6 km/s, or about 3 times the specific velocity of steam rockets (2 km/s, from Isp 200 sec). Such missions include: from the lunar surface to Low Lunar Orbit, (LLO), from LLO to lunar escape, from Low Earth Orbit (LEO) to Geosynchronous Orbit (GEO), from LEO to Earth Escape, from LEO to Mars Transfer Orbit, from LLO to GEO, missions returning payloads from about 10% of the periodic comets using propulsive capture to orbits around Earth itself, and fast, 100 day missions from Lunar Escape to Mars. All the assertions depend entirely and completely on the existence of abundant, nearly pure ice at the permanently dark North and South Poles of the Moon. copyright 1999 American Institute of Physics

  1. Aphid wing induction and ecological costs of alarm pheromone emission under field conditions.

    Directory of Open Access Journals (Sweden)

    Eduardo Hatano

    2010-06-01

    Full Text Available The pea aphid, Acyrthosiphon pisum Harris, (Homoptera: Aphididae releases the volatile sesquiterpene (E-beta-farnesene (EBF when attacked by a predator, triggering escape responses in the aphid colony. Recently, it was shown that this alarm pheromone also mediates the production of the winged dispersal morph under laboratory conditions. The present work tested the wing-inducing effect of EBF under field conditions. Aphid colonies were exposed to two treatments (control and EBF and tested in two different environmental conditions (field and laboratory. As in previous experiments aphids produced higher proportion of winged morphs among their offspring when exposed to EBF in the laboratory but even under field conditions the proportion of winged offspring was higher after EBF application (6.84+/-0.98% compared to the hexane control (1.54+/-0.25%. In the field, the proportion of adult aphids found on the plant at the end of the experiment was lower in the EBF treatment (58.1+/-5.5% than in the control (66.9+/-4.6%, in contrast to the climate chamber test where the numbers of adult aphids found on the plant at the end of the experiment were, in both treatments, similar to the numbers put on the plant initially. Our results show that the role of EBF in aphid wing induction is also apparent under field conditions and they may indicate a potential cost of EBF emission. They also emphasize the importance of investigating the ecological role of induced defences under field conditions.

  2. Generalized conditions for the distributional zero-mass limit of renormalized Feynman amplitudes in Minkowski space

    International Nuclear Information System (INIS)

    Manoukian, E.B.

    1986-01-01

    Generalized conditions (rules) are set up for the existence of the distributional zero-mass limit of renormalized Feynman amplitudes in Minkowski space. These rules are generalizations of rules that have been set up earlier by us and hence are applicable to a larger class of graphs. The study is very general as the vanishing masses are led to vanish at different rates. All subtractions of renormalization are carried out directly in momentum space, about the origin, with the degree of divergence of a subtraction coinciding with the dimensionality of the corresponding subdiagram

  3. A new technique for observationally derived boundary conditions for space weather

    Science.gov (United States)

    Pagano, Paolo; Mackay, Duncan Hendry; Yeates, Anthony Robinson

    2018-04-01

    Context. In recent years, space weather research has focused on developing modelling techniques to predict the arrival time and properties of coronal mass ejections (CMEs) at the Earth. The aim of this paper is to propose a new modelling technique suitable for the next generation of Space Weather predictive tools that is both efficient and accurate. The aim of the new approach is to provide interplanetary space weather forecasting models with accurate time dependent boundary conditions of erupting magnetic flux ropes in the upper solar corona. Methods: To produce boundary conditions, we couple two different modelling techniques, MHD simulations and a quasi-static non-potential evolution model. Both are applied on a spatial domain that covers the entire solar surface, although they extend over a different radial distance. The non-potential model uses a time series of observed synoptic magnetograms to drive the non-potential quasi-static evolution of the coronal magnetic field. This allows us to follow the formation and loss of equilibrium of magnetic flux ropes. Following this a MHD simulation captures the dynamic evolution of the erupting flux rope, when it is ejected into interplanetary space. Results.The present paper focuses on the MHD simulations that follow the ejection of magnetic flux ropes to 4 R⊙. We first propose a technique for specifying the pre-eruptive plasma properties in the corona. Next, time dependent MHD simulations describe the ejection of two magnetic flux ropes, that produce time dependent boundary conditions for the magnetic field and plasma at 4 R⊙ that in future may be applied to interplanetary space weather prediction models. Conclusions: In the present paper, we show that the dual use of quasi-static non-potential magnetic field simulations and full time dependent MHD simulations can produce realistic inhomogeneous boundary conditions for space weather forecasting tools. Before a fully operational model can be produced there are a

  4. Review of hardware cost estimation methods, models and tools applied to early phases of space mission planning

    Science.gov (United States)

    Trivailo, O.; Sippel, M.; Şekercioğlu, Y. A.

    2012-08-01

    The primary purpose of this paper is to review currently existing cost estimation methods, models, tools and resources applicable to the space sector. While key space sector methods are outlined, a specific focus is placed on hardware cost estimation on a system level, particularly for early mission phases during which specifications and requirements are not yet crystallised, and information is limited. For the space industry, cost engineering within the systems engineering framework is an integral discipline. The cost of any space program now constitutes a stringent design criterion, which must be considered and carefully controlled during the entire program life cycle. A first step to any program budget is a representative cost estimate which usually hinges on a particular estimation approach, or methodology. Therefore appropriate selection of specific cost models, methods and tools is paramount, a difficult task given the highly variable nature, scope as well as scientific and technical requirements applicable to each program. Numerous methods, models and tools exist. However new ways are needed to address very early, pre-Phase 0 cost estimation during the initial program research and establishment phase when system specifications are limited, but the available research budget needs to be established and defined. Due to their specificity, for vehicles such as reusable launchers with a manned capability, a lack of historical data implies that using either the classic heuristic approach such as parametric cost estimation based on underlying CERs, or the analogy approach, is therefore, by definition, limited. This review identifies prominent cost estimation models applied to the space sector, and their underlying cost driving parameters and factors. Strengths, weaknesses, and suitability to specific mission types and classes are also highlighted. Current approaches which strategically amalgamate various cost estimation strategies both for formulation and validation

  5. Hospitalisations and costs relating to ambulatory care sensitive conditions in Ireland.

    LENUS (Irish Health Repository)

    Sheridan, A

    2012-03-08

    BACKGROUND: Ambulatory care sensitive conditions (ACSCs) are conditions for which the provision of timely and effective outpatient care can reduce the risks of hospitalisation by preventing, controlling or managing a chronic disease or condition. AIMS: The aims of this study were to report on ACSCs in Ireland, and to provide a baseline for future reference. METHODS: Using HIPE, via Health Atlas Ireland, inpatient discharges classified as ACSCs using definitions from the Victorian ACSC study were extracted for the years 2005-2008. Direct methods of standardisation allowed comparison of rates using the EU standard population as a comparison for national data, and national population as comparison for county data. Costs were estimated using diagnosis-related groups. RESULTS: The directly age-standardised discharge rate for ACSC-related discharges increased slightly, but non-significantly, from 15.40 per 1,000 population in 2005 to 15.75 per 1,000 population in 2008. The number of discharges increased (9.5%) from 63,619 in 2005 to 69,664 in 2008, with the estimated associated hospital costs increasing (31.5%) from 267.8 million in 2005 to 352.2 million in 2008. Across the country, there was considerable variation in the discharge rates for the Top-10 ACSCs for the years 2005-2008. Significantly lower rates of hospitalisation were observed in more urban areas including Cork, Dublin and Galway. The most common ACSC in 2008 was diabetes with complications (29.8%). CONCLUSIONS: The variation in rates observed indicates the scope of reducing hospitalisations and associated costs for ACSCs, across both adult\\'s and children\\'s services and particularly in relation to diabetes complications.

  6. Investigation of a low-cost magneto-inductive magnetometer for space science applications

    Science.gov (United States)

    Regoli, Leonardo H.; Moldwin, Mark B.; Pellioni, Matthew; Bronner, Bret; Hite, Kelsey; Sheinker, Arie; Ponder, Brandon M.

    2018-03-01

    A new sensor for measuring low-amplitude magnetic fields that is ideal for small spacecraft is presented. The novel measurement principle enables the fabrication of a low-cost sensor with low power consumption and with measuring capabilities that are comparable to recent developments for CubeSat applications. The current magnetometer, a software-modified version of a commercial sensor, is capable of detecting fields with amplitudes as low as 8.7 nT at 40 Hz and 2.7 nT at 1 Hz, with a noise floor of 4 pT/Hz at 1 Hz. The sensor has a linear response to less than 3 % over a range of ±100 000 nT. All of these features make the magneto-inductive principle a promising technology for the development of magnetic sensors for both space-borne and ground-based applications to study geomagnetic activity.

  7. Developing Space Weather products and services in Europe – Preface to the Special Issue on COST Action ES0803

    Directory of Open Access Journals (Sweden)

    Belehaki Anna

    2014-01-01

    Full Text Available COST Action ES0803 “Developing Space Weather products and services in Europe” primarily aimed at forming an interdisciplinary network among European scientists dealing with different issues relevant to Geospace as well as warning system developers and operators in order to assess existing Space Weather products and recommend new ones. The work that has been implemented from 2008 to 2012 resulted in advances in modeling and predicting Space Weather, in recommendations for the validation of Space Weather models, in proposals for new Space Weather products and services, and in dissemination, training, and outreach activities. This preface summarizes the most important achievements of this European activity that are detailed in this special issue by the key scientists who participated in COST Action ES0803.

  8. Approaches in the determination of plant nutrient uptake and distribution in space flight conditions

    Science.gov (United States)

    Heyenga, A. G.; Forsman, A.; Stodieck, L. S.; Hoehn, A.; Kliss, M.

    2000-01-01

    The effective growth and development of vascular plants rely on the adequate availability of water and nutrients. Inefficiency in either the initial absorption, transportation, or distribution of these elements are factors which impinge on plant structure and metabolic integrity. The potential effect of space flight and microgravity conditions on the efficiency of these processes is unclear. Limitations in the available quantity of space-grown plant material and the sensitivity of routine analytical techniques have made an evaluation of these processes impractical. However, the recent introduction of new plant cultivating methodologies supporting the application of radionuclide elements and subsequent autoradiography techniques provides a highly sensitive investigative approach amenable to space flight studies. Experiments involving the use of gel based 'nutrient packs' and the radionuclides calcium-45 and iron-59 were conducted on the Shuttle mission STS-94. Uptake rates of the radionuclides between ground and flight plant material appeared comparable.

  9. Common fixed point theorems for fuzzy mappings in metric space under φ-contraction condition

    International Nuclear Information System (INIS)

    Abu-Donia, H.M.

    2007-01-01

    Some common fixed point theorems for multi-valued mappings under φ-contraction condition have been studied by Rashwan [Rashwan RA, Ahmed MA. Fixed points for φ-contraction type multivalued mappings. J Indian Acad Math 1995;17(2):194-204]. Butnariu [Butnariu D. Fixed point for fuzzy mapping. Fuzzy Sets Syst 1982;7:191-207] and Helipern [Hilpern S. Fuzzy mapping and fixed point theorem. J Math Anal Appl 1981;83:566-9] also, discussed some fixed point theorems for fuzzy mappings in the category of metric spaces. In this paper, we discussed some common fixed point theorems for fuzzy mappings in metric space under φ-contraction condition. Our investigation are related to the fuzzy form of Hausdorff metric which is a basic tool for computing Hausdorff dimensions. These dimensions help in understanding ε ∞ -space [El-Naschie MS. On the unification of the fundamental forces and complex time in the ε ∞ -space. Chaos, Solitons and Fractals 2000;11:1149-62] and are used in high energy physics [El-Naschie MS. Wild topology hyperbolic geometry and fusion algebra of high energy particle physics. Chaos, Solitons and Fractals 2002;13:1935-45

  10. Residual stresses relaxation in surface-hardened half-space under creep conditions

    Directory of Open Access Journals (Sweden)

    Vladimir P. Radchenko

    2015-09-01

    Full Text Available We developed the method for solving the problem of residual stresses relaxation in surface-hardened layer of half-space under creep conditions. At the first stage we made the reconstruction of stress-strain state in half-space after plastic surface hardening procedure based on partial information about distribution for one residual stress tensor component experimentally detected. At the second stage using a numerical method we solve the problem of relaxation of self-balanced residual stresses under creep conditions. To solve this problem we introduce the following Cartesian system: x0y plane is aligned with hardened surface of half-space and 0z axis is directed to the depth of hardened layer. We also introduce the hypotheses of plane sections parallel to x0z and y0z planes. Detailed analysis of the problem has been done. Comparison of the calculated data with the corresponding test data was made for plane specimens (rectangular parallelepipeds made of EP742 alloy during T=650°C after the ultrasonic hardening with four hardening modes. We use half-space to model these specimens because penetration's depth of residual stresses is less than specimen general size in two digit exponent. There is enough correspondence of experimental and calculated data. It is shown that there is a decay (in modulus of pressing residual stresses under creep in 1.4–1.6 times.

  11. Common fixed point theorems for fuzzy mappings in metric space under {phi}-contraction condition

    Energy Technology Data Exchange (ETDEWEB)

    Abu-Donia, H.M. [Department of Mathematics, Faculty of Science, Zagazig University, Zagazig (Egypt)

    2007-10-15

    Some common fixed point theorems for multi-valued mappings under {phi}-contraction condition have been studied by Rashwan [Rashwan RA, Ahmed MA. Fixed points for {phi}-contraction type multivalued mappings. J Indian Acad Math 1995;17(2):194-204]. Butnariu [Butnariu D. Fixed point for fuzzy mapping. Fuzzy Sets Syst 1982;7:191-207] and Helipern [Hilpern S. Fuzzy mapping and fixed point theorem. J Math Anal Appl 1981;83:566-9] also, discussed some fixed point theorems for fuzzy mappings in the category of metric spaces. In this paper, we discussed some common fixed point theorems for fuzzy mappings in metric space under {phi}-contraction condition. Our investigation are related to the fuzzy form of Hausdorff metric which is a basic tool for computing Hausdorff dimensions. These dimensions help in understanding {epsilon} {sup {infinity}}-space [El-Naschie MS. On the unification of the fundamental forces and complex time in the {epsilon} {sup {infinity}}-space. Chaos, Solitons and Fractals 2000;11:1149-62] and are used in high energy physics [El-Naschie MS. Wild topology hyperbolic geometry and fusion algebra of high energy particle physics. Chaos, Solitons and Fractals 2002;13:1935-45].

  12. Low cost realization of space-borne synthectic aperture radar - MicroSAR

    Science.gov (United States)

    Carter, D.; Hall, C.

    associated with implementing spaceborne SAR systems is an aspect of work that has been addressed over the past decade by the main S RA system expert companies. As the experimental systems have been realized and understood, so there has been a move to transfer these systems from the research and scientific domains into operational and commercial implementations. The end of the cold war, combined with the ever increasingly competitive telecommunications market, have assisted in driving down the launch costs, a significant cost element in any space system budget. To take maximum benefit from this it is still necessary to be able to make light weight satellites, in the region of 450 Kgs or less. Typically SAR satellites have been in the neighbourhood of 1.5 to 2.5 Tonnes. In order to achieve the low cost systems, not only the satellite mass needs to be tackled but also several other factors:- Design complexity- Production costs- Performance- Calibration and verification A novel approach has been established to address all of these factors. Developments are already in progress to prove the approach and that the low costs are achievable. This is called MicroSAR. This paper starts with an overview of the market status. A description of the MicroSAR system, its developments, calibration philosophy, trade-offs carried out, its performance envelope and an outline of the steps taken to achieve a low cost Synthetic Aperture Radar system are then presented.

  13. Price elasticity and medication use: cost sharing across multiple clinical conditions.

    Science.gov (United States)

    Gatwood, Justin; Gibson, Teresa B; Chernew, Michael E; Farr, Amanda M; Vogtmann, Emily; Fendrick, A Mark

    2014-11-01

    To address the impact that out-of-pocket prices may have on medication use, it is vital to understand how the demand for medications may be affected when patients are faced with changes in the price to acquire treatment and how price responsiveness differs across medication classes.  To examine the impact of cost-sharing changes on the demand for 8 classes of prescription medications. This was a retrospective database analysis of 11,550,363 commercially insured enrollees within the 2005-2009 MarketScan Database. Patient cost sharing, expressed as a price index for each medication class, was the main explanatory variable to examine the price elasticity of demand. Negative binomial fixed effect models were estimated to examine medication fills. The elasticity estimates reflect how use changes over time as a function of changes in copayments. Model estimates revealed that price elasticity of demand ranged from -0.015 to -0.157 within the 8 categories of medications (P  less than  0.01 for 7 of 8 categories). The price elasticity of demand for smoking deterrents was largest (-0.157, P  less than  0.0001), while demand for antiplatelet agents was not responsive to price (P  greater than 0.05). The price elasticity of demand varied considerably by medication class, suggesting that the influence of cost sharing on medication use may be related to characteristics inherent to each medication class or underlying condition.

  14. Conditions for extinction events in chemical reaction networks with discrete state spaces.

    Science.gov (United States)

    Johnston, Matthew D; Anderson, David F; Craciun, Gheorghe; Brijder, Robert

    2018-05-01

    We study chemical reaction networks with discrete state spaces and present sufficient conditions on the structure of the network that guarantee the system exhibits an extinction event. The conditions we derive involve creating a modified chemical reaction network called a domination-expanded reaction network and then checking properties of this network. Unlike previous results, our analysis allows algorithmic implementation via systems of equalities and inequalities and suggests sequences of reactions which may lead to extinction events. We apply the results to several networks including an EnvZ-OmpR signaling pathway in Escherichia coli.

  15. Tension cost correlates with mechanical and biochemical parameters in different myocardial contractility conditions

    Directory of Open Access Journals (Sweden)

    Cleci M. Moreira

    2012-01-01

    Full Text Available OBJECTIVES: Tension cost, the ratio of myosin ATPase activity to tension, reflects the economy of tension development in the myocardium. To evaluate the mechanical advantage represented by the tension cost, we studied papillary muscle contractility and the activity of myosin ATPase in the left ventricles in normal and pathophysiological conditions. METHODS: Experimental protocols were performed using rat left ventricles from: (1 streptozotocin-induced diabetic and control Wistar rats; (2 N-nitro-L-arginine methyl ester (L-NAME hypertensive and untreated Wistar rats; (3 deoxycorticosterone acetate (DOCA salt-treated, nephrectomized and salt- and DOCA-treated rats; (4 spontaneous hypertensive rats (SHR and Wistar Kyoto (WKY rats; (5 rats with myocardial infarction and shamoperated rats. The isometric force, tetanic tension, and the activity of myosin ATPase were measured. RESULTS: The results obtained from infarcted, diabetic, and deoxycorticosterone acetate-salt-treated rats showed reductions in twitch and tetanic tension compared to the control and sham-operated groups. Twitch and tetanic tension increased in the N-nitro-L-arginine methyl ester-treated rats compared with the Wistar rats. Myosin ATPase activity was depressed in the infarcted, diabetic, and deoxycorticosterone acetate salt-treated rats compared with control and sham-operated rats and was increased in N-nitro-L-arginine methyl ester-treated rats. These parameters did not differ between SHR and WKY rats. In the studied conditions (e.g., post-myocardial infarction, deoxycorticosterone acetate salt-induced hypertension, chronic N-nitro-L-arginine methyl ester treatment, and streptozotocin-induced diabetes, a positive correlation between force or plateau tetanic tension and myosin ATPase activity was observed. CONCLUSION: Our results suggest that the myocardium adapts to force generation by increasing or reducing the tension cost to maintain myocardial contractility with a better

  16. Adsorbent Alkali Conditioning for Uranium Adsorption from Seawater. Adsorbent Performance and Technology Cost Evaluation

    International Nuclear Information System (INIS)

    Tsouris, Costas; Mayes, Richard T.; Janke, Christopher James; Dai, Sheng; Das, S.; Liao, W.P.; Kuo, Li-Jung; Wood, Jordana; Gill, Gary; Byers, Maggie Flicker; Schneider, Eric

    2015-01-01

    The Fuel Resources program of the Fuel Cycle Research and Development program of the Office of Nuclear Energy (NE) is focused on identifying and implementing actions to assure that nuclear fuel resources are available in the United States. An immense source of uranium is seawater, which contains an estimated amount of 4.5 billion tonnes of dissolved uranium. This unconventional resource can provide a price cap and ensure centuries of uranium supply for future nuclear energy production. NE initiated a multidisciplinary program with participants from national laboratories, universities, and research institutes to enable technical breakthroughs related to uranium recovery from seawater. The goal is to develop advanced adsorbents to reduce the seawater uranium recovery technology cost and uncertainties. Under this program, Oak Ridge National Laboratory (ORNL) has developed a new amidoxime-based adsorbent of high surface area, which tripled the uranium capacity of leading Japanese adsorbents. Parallel efforts have been focused on the optimization of the physicochemical and operating parameters used during the preparation of the adsorbent for deployment. A set of parameters that need to be optimized are related to the conditioning of the adsorbent with alkali solution, which is necessary prior to adsorbent deployment. Previous work indicated that alkali-conditioning parameters significantly affect the adsorbent performance. Initiated in 2014, this study had as a goal to determine optimal parameters such as base type and concentration, temperature, and duration of conditioning that maximize the uranium adsorption performance of amidoxime functionalized adsorbent, while keeping the cost of uranium production low. After base-treatment at various conditions, samples of adsorbent developed at ORNL were tested in this study with batch simulated seawater solution of 8-ppm uranium concentration, batch seawater spiked with uranium nitrate at 75-100 ppb uranium, and continuous

  17. Adsorbent Alkali Conditioning for Uranium Adsorption from Seawater. Adsorbent Performance and Technology Cost Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Tsouris, Costas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Mayes, Richard T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Janke, Christopher James [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dai, Sheng [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Das, S. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Liao, W. -P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kuo, Li-Jung [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wood, Jordana [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gill, Gary [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Byers, Maggie Flicker [Univ. of Texas, Austin, TX (United States); Schneider, Eric [Univ. of Texas, Austin, TX (United States)

    2015-09-30

    The Fuel Resources program of the Fuel Cycle Research and Development program of the Office of Nuclear Energy (NE) is focused on identifying and implementing actions to assure that nuclear fuel resources are available in the United States. An immense source of uranium is seawater, which contains an estimated amount of 4.5 billion tonnes of dissolved uranium. This unconventional resource can provide a price cap and ensure centuries of uranium supply for future nuclear energy production. NE initiated a multidisciplinary program with participants from national laboratories, universities, and research institutes to enable technical breakthroughs related to uranium recovery from seawater. The goal is to develop advanced adsorbents to reduce the seawater uranium recovery technology cost and uncertainties. Under this program, Oak Ridge National Laboratory (ORNL) has developed a new amidoxime-based adsorbent of high surface area, which tripled the uranium capacity of leading Japanese adsorbents. Parallel efforts have been focused on the optimization of the physicochemical and operating parameters used during the preparation of the adsorbent for deployment. A set of parameters that need to be optimized are related to the conditioning of the adsorbent with alkali solution, which is necessary prior to adsorbent deployment. Previous work indicated that alkali-conditioning parameters significantly affect the adsorbent performance. Initiated in 2014, this study had as a goal to determine optimal parameters such as base type and concentration, temperature, and duration of conditioning that maximize the uranium adsorption performance of amidoxime functionalized adsorbent, while keeping the cost of uranium production low. After base-treatment at various conditions, samples of adsorbent developed at ORNL were tested in this study with batch simulated seawater solution of 8-ppm uranium concentration, batch seawater spiked with uranium nitrate at 75-100 ppb uranium, and continuous

  18. The effect of environmental parameters to dust concentration in air-conditioned space

    Science.gov (United States)

    Ismail, A. M. M.; Manssor, N. A. S.; Nalisa, A.; Yahaya, N.

    2017-08-01

    Malaysia has a wet and hot climate, therefore most of the spaces are air conditioned. The environment might affect dust concentration inside a space and affect the indoor air quality (IAQ). The main objective of this study is to study the dust concentration collected inside enclosed air-conditioned space. The measurement was done physically at four selected offices and two classrooms using a number of equipment to measure the dust concentration and environmental parameters which are temperature and relative air humidity. It was found that the highest dust concentration produced in office (temperature of 24.7°C, relative humidity of 66.5%) is 0.075 mg/m3, as compared to classroom, the highest dust concentration produced is 0.060 mg/m3 office (temperature of 25.9°C, relative humidity of 64.0%). However, both measurements show that value still within the safety level set by DOSH Malaysia (2005-2010) and ASHRAE 62.2 2016. The office contained higher dust concentration compared to classroom because of frequent movement transpires daily due to the functional of the offices.

  19. Instantaneous Metabolic Cost of Walking: Joint-Space Dynamic Model with Subject-Specific Heat Rate.

    Directory of Open Access Journals (Sweden)

    Dustyn Roberts

    Full Text Available A subject-specific model of instantaneous cost of transport (ICOT is introduced from the joint-space formulation of metabolic energy expenditure using the laws of thermodynamics and the principles of multibody system dynamics. Work and heat are formulated in generalized coordinates as functions of joint kinematic and dynamic variables. Generalized heat rates mapped from muscle energetics are estimated from experimental walking metabolic data for the whole body, including upper-body and bilateral data synchronization. Identified subject-specific energetic parameters-mass, height, (estimated maximum oxygen uptake, and (estimated maximum joint torques-are incorporated into the heat rate, as opposed to the traditional in vitro and subject-invariant muscle parameters. The total model metabolic energy expenditure values are within 5.7 ± 4.6% error of the measured values with strong (R2 > 0.90 inter- and intra-subject correlations. The model reliably predicts the characteristic convexity and magnitudes (0.326-0.348 of the experimental total COT (0.311-0.358 across different subjects and speeds. The ICOT as a function of time provides insights into gait energetic causes and effects (e.g., normalized comparison and sensitivity with respect to walking speed and phase-specific COT, which are unavailable from conventional metabolic measurements or muscle models. Using the joint-space variables from commonly measured or simulated data, the models enable real-time and phase-specific evaluations of transient or non-periodic general tasks that use a range of (aerobic energy pathway similar to that of steady-state walking.

  20. An efficient heuristic method for dynamic portfolio selection problem under transaction costs and uncertain conditions

    Science.gov (United States)

    Najafi, Amir Abbas; Pourahmadi, Zahra

    2016-04-01

    Selecting the optimal combination of assets in a portfolio is one of the most important decisions in investment management. As investment is a long term concept, looking into a portfolio optimization problem just in a single period may cause loss of some opportunities that could be exploited in a long term view. Hence, it is tried to extend the problem from single to multi-period model. We include trading costs and uncertain conditions to this model which made it more realistic and complex. Hence, we propose an efficient heuristic method to tackle this problem. The efficiency of the method is examined and compared with the results of the rolling single-period optimization and the buy and hold method which shows the superiority of the proposed method.

  1. Studies on penetration of antibiotic in bacterial cells in space conditions (7-IML-1)

    Science.gov (United States)

    Tixador, R.

    1992-01-01

    The Cytos 2 experiment was performed aboard Salyut 7 in order to test the antibiotic sensitivity of bacteria cultivated in vitro in space. An increase of the Minimal Inhibitory Concentration (MIC) in the inflight cultures (i.e., an increase of the antibiotic resistance) was observed. Complementary studies of the ultrastructure showed a thickening of the cell envelope. In order to confirm the results of the Cytos 2 experiment, we performed the ANTIBIO experiment during the D1 mission to try to differentiate, by means of the 1 g centrifuge in the Biorack, between the biological effects of cosmic rays and those caused by microgravity conditions. The originality of this experiment was in the fact that it was designed to test the antibiotic sensitivity of bacteria cultivated in vitro during the orbital phase of the flight. The results show an increase in resistance to Colistin in in-flight bacteria. The MIC is practically double in the in-flight cultures. A cell count of living bacteria in the cultures containing the different Colistin concentrations showed a significant difference between the cultures developed during space flight and the ground based cultures. The comparison between the 1 g and 0 g in-flight cultures show similar behavior for the two sets. Nevertheless, a small difference between the two sets of ground based control cultures was noted. The cultures developed on the ground centrifuge (1.4 g) present a slight decrease in comparison with the cultures developed in the static rack (1 g). In order to approach the mechanisms of the increase of antibiotic resistance on bacteria cultivated in vitro in space, we have proposed the study on penetration of antibiotics in bacterial cells in space conditions. This experiment was selected for the International Microgravity Laboratory 1 (IML-1) mission.

  2. Investigation of a low-cost magneto-inductive magnetometer for space science applications

    Directory of Open Access Journals (Sweden)

    L. H. Regoli

    2018-03-01

    Full Text Available A new sensor for measuring low-amplitude magnetic fields that is ideal for small spacecraft is presented. The novel measurement principle enables the fabrication of a low-cost sensor with low power consumption and with measuring capabilities that are comparable to recent developments for CubeSat applications. The current magnetometer, a software-modified version of a commercial sensor, is capable of detecting fields with amplitudes as low as 8.7 nT at 40 Hz and 2.7 nT at 1 Hz, with a noise floor of 4 pT∕Hz at 1 Hz. The sensor has a linear response to less than 3 % over a range of ±100 000 nT. All of these features make the magneto-inductive principle a promising technology for the development of magnetic sensors for both space-borne and ground-based applications to study geomagnetic activity.

  3. Potential low cost, safe, high efficiency propellant for future space program

    Science.gov (United States)

    Zhou, D.

    2005-03-01

    Mixtures of nanometer or micrometer sized carbon powder suspended in hydrogen and methane/hydrogen mixtures are proposed as candidates for low cost, high efficiency propellants for future space programs. While liquid hydrogen has low weight and high heat of combustion per unit mass, because of the low mass density the heat of combustion per unit volume is low, and the liquid hydrogen storage container must be large. The proposed propellants can produce higher gross heat combustion with small volume with trade off of some weight increase. Liquid hydrogen can serve as the fluid component of the propellant in the mixtures and thus used by current rocket engine designs. For example, for the same volume a mixture of 5% methane and 95% hydrogen, can lead to an increase in the gross heat of combustion by about 10% and an increase in the Isp (specific impulse) by 21% compared to a pure liquid hydrogen propellant. At liquid hydrogen temperatures of 20.3 K, methane will be in solid state, and must be formed as fine granules (or slush) to satisfy the requirement of liquid propellant engines.

  4. Survival of pathogenic bacteria under nutrient starvation conditions. [aboard orbiting space stations

    Science.gov (United States)

    Boyle, Michael; Ford, Tim; Mitchell, Ralph; Maki, James

    1990-01-01

    The survival of opportunistic pathogenic microorganisms in water, under nutrient-limiting conditions, has been investigated in order to ascertain whether human pathogens can survive within a water-distribution system of the kind proposed for the NASA Space Station. Cultures of a strain of pseudomonas aeruginosa and two strains of staphylococcus aureus were incubated at 10, 25, or 37 C, and samples at 1 day, 1 week, 1 month, and six weeks. While neither of the staphylococcus strains tested were detected after 1 week of starvation, the pseudomonas strain can survive in deionized water at all three temperatures.

  5. Dressing method and quadratic bundles related to symmetric spaces. Vanishing boundary conditions

    Science.gov (United States)

    Valchev, T. I.

    2016-02-01

    We consider quadratic bundles related to Hermitian symmetric spaces of the type SU(m + n)/S(U(m) × U(n)). The simplest representative of the corresponding integrable hierarchy is given by a multi-component Kaup-Newell derivative nonlinear Schrödinger equation which serves as a motivational example for our general considerations. We extensively discuss how one can apply Zakharov-Shabat's dressing procedure to derive reflectionless potentials obeying zero boundary conditions. Those could be used for one to construct fast decaying solutions to any nonlinear equation belonging to the same hierarchy. One can distinguish between generic soliton type solutions and rational solutions.

  6. Foundations of complex analysis in non locally convex spaces function theory without convexity condition

    CERN Document Server

    Bayoumi, A

    2003-01-01

    All the existing books in Infinite Dimensional Complex Analysis focus on the problems of locally convex spaces. However, the theory without convexity condition is covered for the first time in this book. This shows that we are really working with a new, important and interesting field. Theory of functions and nonlinear analysis problems are widespread in the mathematical modeling of real world systems in a very broad range of applications. During the past three decades many new results from the author have helped to solve multiextreme problems arising from important situations, non-convex and

  7. Simulation Evaluation of Controller-Managed Spacing Tools under Realistic Operational Conditions

    Science.gov (United States)

    Callantine, Todd J.; Hunt, Sarah M.; Prevot, Thomas

    2014-01-01

    Controller-Managed Spacing (CMS) tools have been developed to aid air traffic controllers in managing high volumes of arriving aircraft according to a schedule while enabling them to fly efficient descent profiles. The CMS tools are undergoing refinement in preparation for field demonstration as part of NASA's Air Traffic Management (ATM) Technology Demonstration-1 (ATD-1). System-level ATD-1 simulations have been conducted to quantify expected efficiency and capacity gains under realistic operational conditions. This paper presents simulation results with a focus on CMS-tool human factors. The results suggest experienced controllers new to the tools find them acceptable and can use them effectively in ATD-1 operations.

  8. Lunar and planetary surface conditions advances in space science and technology

    CERN Document Server

    Weil, Nicholas A

    1965-01-01

    Lunar and Planetary Surface Conditions considers the inferential knowledge concerning the surfaces of the Moon and the planetary companions in the Solar System. The information presented in this four-chapter book is based on remote observations and measurements from the vantage point of Earth and on the results obtained from accelerated space program of the United States and U.S.S.R. Chapter 1 presents the prevalent hypotheses on the origin and age of the Solar System, followed by a brief description of the methods and feasibility of information acquisition concerning lunar and planetary data,

  9. Reducing Idle Power Consumption in Office Spaces Saves U.S. Navy in Energy Costs (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-04-01

    As part of a two-year project to demonstrate energy efficiency measures, renewable energy generation, and energy systems integration, the National Renewable Energy Laboratory (NREL) has identified advanced plug load controls as a promising technology for reducing energy use and related costs in the U.S. Navy's Naval Facilities Engineering Command (NAVFAC) office spaces.

  10. Application of Pettis integration to differential inclusions with three-point boundary conditions in Banach spaces

    Directory of Open Access Journals (Sweden)

    Imen Boutana

    2007-12-01

    Full Text Available This paper provide some applications of Pettis integration to differential inclusions in Banach spaces with three point boundary conditions of the form $$ ddot{u}(t in F(t,u(t,dot u(t+H(t,u(t,dot u(t,quad hbox{a.e. } t in [0,1], $$ where $F$ is a convex valued multifunction upper semicontinuous on $Eimes E$ and $H$ is a lower semicontinuous multifunction. The existence of solutions is obtained under the non convexity condition for the multifunction $H$, and the assumption that $F(t,x,ysubset Gamma_{1}(t$, $H(t,x,ysubset Gamma_{2}(t$, where the multifunctions $Gamma_{1},Gamma_{2}:[0,1] ightrightarrows E$ are uniformly Pettis integrable.

  11. ''Free-space'' boundary conditions for the time-dependent wave equation

    International Nuclear Information System (INIS)

    Lindman, E.L.

    1975-01-01

    Boundary conditions for the discrete wave equation which act like an infinite region of free space in contact with the computational region can be constructed using projection operators. Propagating and evanescent waves coming from within the computational region generate no reflected waves as they cross the boundary. At the same time arbitrary waves may be launched into the computational region. Well known projection operators for one-dimensional waves may be used for this purpose in one dimension. Extensions of these operators to higher dimensions along with numerically efficient approximations to them are described for higher-dimensional problems. The separation of waves into ingoing and outgoing waves inherent in these boundary conditions greatly facilitates diagnostics

  12. Modelling the perception of weather conditions by users of outdoor public spaces

    Science.gov (United States)

    Andrade, H.; Oliveira, S.; Alcoforado, M.-J.

    2009-09-01

    Outdoor public spaces play an important role for the quality of life in urban areas. Their usage depends, among other factors, on the bioclimatic comfort of the users. Climate change can modify the uses of outdoor spaces, by changing temperature and rainfall patterns. Understanding the way people perceive the microclimatic conditions is an important tool to the design of more comfortable outdoor spaces and in anticipating future needs to cope with climate change impacts. The perception of bioclimatic comfort by users of two different outdoor spaces was studied in Lisbon. A survey of about one thousand inquires was carried out simultaneously with weather measurements (air temperature, wind speed, relative humidity and solar and long wave radiation), during the years 2006 and 2007. The aim was to assess the relationships between weather variables, the individual characteristics of people (such as age and gender, among others) and their bioclimatic comfort. The perception of comfort was evaluated through the preference votes of the interviewees, which consisted on their answers concerning the desire to decrease, maintain or increase the values of the different weather parameters, in order to improve their comfort at the moment of the interview. The perception of the atmospheric conditions and of the bioclimatic comfort are highly influenced by subjective factors, which are difficult to integrate in a model. Nonetheless, the use of the multiple logistic regression allows the definition of patterns in the quantitative relation between preference votes and environmental and personal parameters. The thermal preference depends largely on the season and is associated with wind speed. Comfort in relation to wind depends not only on the speed but also on turbulence: a high variability in wind speed is generally perceived as uncomfortable. It was also found that the acceptability of warmer conditions is higher than for cooler conditions and the majority of people declared

  13. An Accelerated Development, Reduced Cost Approach to Lunar/Mars Exploration Using a Modular NTR-Based Space Transportation System

    Science.gov (United States)

    Borowski, S.; Clark, J.; Sefcik, R.; Corban, R.; Alexander, S.

    1995-01-01

    The results of integrated systems and mission studies are presented which quantify the benefits and rationale for developing a common, modular lunar/Mars space transportation system (STS) based on nuclear thermal rocket (NTR) technology. At present NASA's Exploration Program Office (ExPO) is considering chemical propulsion for an 'early return to the Moon' and NTR propulsion for the more demanding Mars missions to follow. The time and cost to develop these multiple systems are expected to be significant. The Nuclear Propulsion Office (NPO) has examined a variety of lunar and Mars missions and heavy lift launch vehicle (HLLV) options in an effort to determine a 'standardized' set of engine and stage components capable of satisfying a wide range of Space Exploration Initiative (SEI) missions. By using these components in a 'building block' fashion, a variety of single and multi-engine lunar and Mars vehicles can be configured. For NASA's 'First Lunar Outpost' (FLO) mission, an expendable NTR stage powered by two 50 klbf engines can deliver approximately 96 metric tons (t) to translunar injection (TLI) conditions for an initial mass in low earth orbit (IMLEO) of approximately 198 t compared to 250 t for a cryogenic chemical TLI stage. The NTR stage liquid hydrogen (LH2) tank has a 10 m diameter, 14.5 m length, and 66 t LH2 capacity. The NTR utilizes a UC-ZrC-graphite 'composite' fuel with a specific impulse (Isp) capability of approximately 900 s and an engine thrust-to-weight ratio of approximately 4.3. By extending the size and LH2 capacity of the lunar NTR stage to approximately 20 m and 96 t, respectively, a single launch Mars cargo vehicle capable of delivering approximately 50 t of surface payload is possible. Three 50 klbf NTR engines and the two standardized LH2 tank sizes developed for lunar and Mars cargo vehicle applications would be used to configure the Mars piloted vehicle for a mission as early as 2010. The paper describes the features of the 'common

  14. Dynamics and cultural specifics of information needs under conditions of long-term space flight

    Science.gov (United States)

    Feichtinger, Elena; Shved, Dmitry; Gushin, Vadim

    Life in conditions of space flight or chamber study with prolonged isolation is associated with lack of familiar stimuli (sensory deprivation), monotony, significant limitation of communication, and deficit of information and media content (Myasnikov V.I., Stepanova S.I. et al., 2000). Fulfillment of a simulation experiment or flight schedule implies necessity of performance of sophisticated tasks and decision making with limited means of external support. On the other hand, the “stream” of information from the Mission Control (MC) and PI’s (reminders about different procedures to be performed, requests of reports, etc.) is often inadequate to communication needs of crewmembers. According to the theory of “information stress” (Khananashvili M.M., 1984), a distress condition could be formed if: a) it’s necessary to process large amounts of information and make decisions under time pressure; b) there is a prolonged deficit of necessary (e.g. for decision making) information. Thus, we suppose that one of the important goals of psychological support of space or space simulation crews should be forming of favorable conditions of information environment. For that purpose, means of crew-MC information exchange (quantitative characteristics and, if possible, content of radiograms, text and video messages, etc.) should be studied, as well as peculiarities of the crewmembers’ needs in different information and media content, and their reactions to incoming information. In the space simulation experiment with 520-day isolation, communication of international crew with external parties had been studied. Dynamics of quantitative and content characteristics of the crew’s messages was related to the experiment’s stage, presence of “key” events in the schedule (periods of high autonomy, simulated “planetary landing”, etc.), as well as to events not related to the experiment (holidays, news, etc.). It was shown that characteristics of information exchange

  15. Perovskite-based Photovoltaics: A New Pathway to Ultra- Low-Cost Space Power

    Data.gov (United States)

    National Aeronautics and Space Administration — We will determine if the lifetime performance of new perovskite-based solar cells can be engineered for long-term performance for space applications. We will utilize...

  16. Hardwood? Carpet? or Tile? A comparison of flooring costs under residential conditions

    Science.gov (United States)

    David G. Martens; David G. Martens

    1971-01-01

    Initial installation cost, annual maintenance cost, and total long-term cost are important in the purchase of flooring products. Before deciding on a flooring material, the prudent buyer will consider each of these in relation to his personal desires. From these evaluations, he will then be able to select the flooring material that is best suited to his individual...

  17. Nonlocal beam models for buckling of nanobeams using state-space method regarding different boundary conditions

    International Nuclear Information System (INIS)

    Sahmani, S.; Ansari, R.

    2011-01-01

    Buckling analysis of nanobeams is investigated using nonlocal continuum beam models of the different classical beam theories namely as Euler-Bernoulli beam theory (EBT), Timoshenko beam theory (TBT), and Levinson beam theory (LBT). To this end, Eringen's equations of nonlocal elasticity are incorporated into the classical beam theories for buckling of nanobeams with rectangular cross-section. In contrast to the classical theories, the nonlocal elastic beam models developed here have the capability to predict critical buckling loads that allowing for the inclusion of size effects. The values of critical buckling loads corresponding to four commonly used boundary conditions are obtained using state-space method. The results are presented for different geometric parameters, boundary conditions, and values of nonlocal parameter to show the effects of each of them in detail. Then the results are fitted with those of molecular dynamics simulations through a nonlinear least square fitting procedure to find the appropriate values of nonlocal parameter for the buckling analysis of nanobeams relevant to each type of nonlocal beam model and boundary conditions analysis

  18. Nonlocal beam models for buckling of nanobeams using state-space method regarding different boundary conditions

    Energy Technology Data Exchange (ETDEWEB)

    Sahmani, S.; Ansari, R. [University of Guilan, Rasht (Iran, Islamic Republic of)

    2011-09-15

    Buckling analysis of nanobeams is investigated using nonlocal continuum beam models of the different classical beam theories namely as Euler-Bernoulli beam theory (EBT), Timoshenko beam theory (TBT), and Levinson beam theory (LBT). To this end, Eringen's equations of nonlocal elasticity are incorporated into the classical beam theories for buckling of nanobeams with rectangular cross-section. In contrast to the classical theories, the nonlocal elastic beam models developed here have the capability to predict critical buckling loads that allowing for the inclusion of size effects. The values of critical buckling loads corresponding to four commonly used boundary conditions are obtained using state-space method. The results are presented for different geometric parameters, boundary conditions, and values of nonlocal parameter to show the effects of each of them in detail. Then the results are fitted with those of molecular dynamics simulations through a nonlinear least square fitting procedure to find the appropriate values of nonlocal parameter for the buckling analysis of nanobeams relevant to each type of nonlocal beam model and boundary conditions analysis.

  19. Development and application of a model for the analysis of trades between space launch system operations and acquisition costs

    Science.gov (United States)

    Nix, Michael B.

    2005-12-01

    Early design decisions in the development of space launch systems determine the costs to acquire and operate launch systems. Some sources indicate that as much as 90% of life cycle costs are fixed by the end of the critical design review phase. System characteristics determined by these early decisions are major factors in the acquisition cost of flight hardware elements and facilities and influence operations costs through the amount of maintenance and support labor required to sustain system function. Operations costs are also dependent on post-development management decisions regarding how much labor will be deployed to meet requirements of market demand and ownership profit. The ability to perform early trade-offs between these costs is vital to the development of systems that have the necessary capacity to provide service and are profitable to operate. An Excel-based prototype model was developed for making early analyses of trade-offs between the costs to operate a space launch system and to acquire the necessary assets to meet a given set of operational requirements. The model, integrating input from existing models and adding missing capability, allows the user to make such trade-offs across a range of operations concepts (required flight rates, staffing levels, shifts per workday, workdays per week and per year, unreliability, wearout and depot maintenance) and the number, type and capability of assets (flight hardware elements, processing and supporting facilities and infrastructure). The costs and capabilities of hypothetical launch systems can be modeled as a function of interrelated turnaround times and labor resource levels, and asset loss and retirement. The number of flight components and facilities required can be calculated and the operations and acquisition costs compared for a specified scenario. Findings, based on the analysis of a hypothetical two stage to orbit, reusable, unmanned launch system, indicate that the model is suitable for the

  20. Shared visions: Partnership of Rockwell International and NASA Cost Effectiveness Enhancements (CEE) for the space shuttle system integration program

    Science.gov (United States)

    Bejmuk, Bohdan I.; Williams, Larry

    As a result of limited resources and tight fiscal constraints over the past several years, the defense and aerospace industries have experienced a downturn in business activity. The impact of fewer contracts being awarded has placed a greater emphasis for effectiveness and efficiency on industry contractors. It is clear that a reallocation of resources is required for America to continue to lead the world in space and technology. The key to technological and economic survival is the transforming of existing programs, such as the Space Shuttle Program, into more cost efficient programs so as to divert the savings to other NASA programs. The partnership between Rockwell International and NASA and their joint improvement efforts that resulted in significant streamlining and cost reduction measures to Rockwell International Space System Division's work on the Space Shuttle System Integration Contract is described. This work was a result of an established Cost Effectiveness Enhancement (CEE) Team formed initially in Fiscal Year 1991, and more recently expanded to a larger scale CEE Initiative in 1992. By working closely with the customer in agreeing to contract content, obtaining management endorsement and commitment, and involving the employees in total quality management (TQM) and continuous improvement 'teams,' the initial annual cost reduction target was exceeded significantly. The CEE Initiative helped reduce the cost of the Shuttle Systems Integration contract while establishing a stronger program based upon customer needs, teamwork, quality enhancements, and cost effectiveness. This was accomplished by systematically analyzing, challenging, and changing the established processes, practices, and systems. This examination, in nature, was work intensive due to the depth and breadth of the activity. The CEE Initiative has provided opportunities to make a difference in the way Rockwell and NASA work together - to update the methods and processes of the organizations

  1. Shared visions: Partnership of Rockwell International and NASA Cost Effectiveness Enhancements (CEE) for the space shuttle system integration program

    Science.gov (United States)

    Bejmuk, Bohdan I.; Williams, Larry

    1992-01-01

    As a result of limited resources and tight fiscal constraints over the past several years, the defense and aerospace industries have experienced a downturn in business activity. The impact of fewer contracts being awarded has placed a greater emphasis for effectiveness and efficiency on industry contractors. It is clear that a reallocation of resources is required for America to continue to lead the world in space and technology. The key to technological and economic survival is the transforming of existing programs, such as the Space Shuttle Program, into more cost efficient programs so as to divert the savings to other NASA programs. The partnership between Rockwell International and NASA and their joint improvement efforts that resulted in significant streamlining and cost reduction measures to Rockwell International Space System Division's work on the Space Shuttle System Integration Contract is described. This work was a result of an established Cost Effectiveness Enhancement (CEE) Team formed initially in Fiscal Year 1991, and more recently expanded to a larger scale CEE Initiative in 1992. By working closely with the customer in agreeing to contract content, obtaining management endorsement and commitment, and involving the employees in total quality management (TQM) and continuous improvement 'teams,' the initial annual cost reduction target was exceeded significantly. The CEE Initiative helped reduce the cost of the Shuttle Systems Integration contract while establishing a stronger program based upon customer needs, teamwork, quality enhancements, and cost effectiveness. This was accomplished by systematically analyzing, challenging, and changing the established processes, practices, and systems. This examination, in nature, was work intensive due to the depth and breadth of the activity. The CEE Initiative has provided opportunities to make a difference in the way Rockwell and NASA work together - to update the methods and processes of the organizations

  2. Modeling Space-Time Dependent Helium Bubble Evolution in Tungsten Armor under IFE Conditions

    International Nuclear Information System (INIS)

    Qiyang Hu; Shahram Sharafat; Nasr Ghoniem

    2006-01-01

    The High Average Power Laser (HAPL) program is a coordinated effort to develop Laser Inertial Fusion Energy. The implosion of the D-T target produces a spectrum of neutrons, X-rays, and charged particles, which arrive at the first wall (FW) at different times within about 2.5 μs at a frequency of 5 to 10 Hz. Helium is one of several high-energy charged particle constituents impinging on the candidate tungsten armored low activation ferritic steel First Wall. The spread of the implanted debris and burn helium energies results in a unique space-time dependent implantation profile that spans about 10 μm in tungsten. Co-implantation of X-rays and other ions results in spatially dependent damage profiles and rapid space-time dependent temperature spikes and gradients. The rate of helium transport and helium bubble formation will vary significantly throughout the implanted region. Furthermore, helium will also be transported via the migration of helium bubbles and non-equilibrium helium-vacancy clusters. The HEROS code was developed at UCLA to model the spatial and time-dependent helium bubble nucleation, growth, coalescence, and migration under transient damage rates and transient temperature gradients. The HEROS code is based on kinetic rate theory, which includes clustering of helium and vacancies, helium mobility, helium-vacancy cluster stability, cavity nucleation and growth and other microstructural features such as interstitial loop evolution, grain boundaries, and precipitates. The HEROS code is based on space-time discretization of reaction-diffusion type equations to account for migration of mobile species between neighboring bins as single atoms, clusters, or bubbles. HAPL chamber FW implantation conditions are used to model helium bubble evolution in the implanted tungsten. Helium recycling rate predictions are compared with experimental results of helium ion implantation experiments. (author)

  3. Space structures, power, and power conditioning; Proceedings of the Meeting, Los Angeles, CA, Jan. 11-13, 1988

    International Nuclear Information System (INIS)

    Askew, R.F.

    1988-01-01

    Various papers on space structures, power, and power conditioning are presented. Among the topics discussed are: heterogeneous gas core reaction for space nuclear power, pulsed gas core reactor for burst power, fundamental considerations of gas core reactor systems, oscillating thermionic conversion for high-density space power, thermoelectromagnetic pumps for space nuclear power systems, lightweight electrochemical converter for space power applications, ballistic acceleration by superheated hydrogen, laser-induced current switching in gaseous discharge, electron-beam-controlled semiconductor switches, laser-controlled semiconductor closing and opening switch. Also addressed are: semiconductor-metal eutectic composites for high-power switching, optical probes for the characterization of surface breakdown, 40 kV/20 kA pseudospark switch for laser applications, insulation direction for high-power space systems, state space simulation of spacecraft power systems, structural vibration of space power station systems, minimum-time control of large space structures, novel fusion reaction for space power and propulsion, repetition rate system evaluations, cryogenic silicon photoconductive switches for high-power lasers, multilevel diamondlike carbon capacitor structure, surface breakdown of prestressed insulators, C-Mo and C-Zr alloys for space power systems, magnetic insulation for the space environment

  4. Regularization in Hilbert space under unbounded operators and general source conditions

    International Nuclear Information System (INIS)

    Hofmann, Bernd; Mathé, Peter; Von Weizsäcker, Heinrich

    2009-01-01

    The authors study ill-posed equations with unbounded operators in Hilbert space. This setup has important applications, but only a few theoretical studies are available. First, the question is addressed and answered whether every element satisfies some general source condition with respect to a given self-adjoint unbounded operator. This generalizes a previous result from Mathé and Hofmann (2008 Inverse Problems 24 015009). The analysis then proceeds to error bounds for regularization, emphasizing some specific points for regularization under unbounded operators. The study finally reviews two examples within the light of the present study, as these are fractional differentiation and some Cauchy problems for the Helmholtz equation, both studied previously and in more detail by U Tautenhahn and co-authors

  5. Quadrupole beam-transport experiment for heavy ions under extreme space charge conditions

    International Nuclear Information System (INIS)

    Chupp, W.; Faltens, A.; Hartwig, E.C.

    1983-03-01

    A Cs ion-beam-transport experiment is in progress to study beam behavior under extreme space-charge conditions. A five-lens section matches the beam into a periodic electrostatic quadrupole FODO channel and its behavior is found to agree with predictions. With the available parameters (less than or equal to 200 keV, less than or equal to 20 mA, πepsilon/sub n/ greater than or equal to 10 - 7 π rad-m, up to 41 periods) the transverse (betatron) occillation frequency (nu) can be depressed down to one-tenth of its zero current value (nu/sub 0/), where nu/sup 2/ = nu/sub 0//sup 2/ -#betta#/sub p/ 2 /2, and #betta#/sub p/ is the beam plasma frequency. The current can be controlled by adjustment of the gun and the emittance can be controlled independently by means of a set of charged grids

  6. Embryogenesis and organogenesis of Carausius morosus under space flight conditions (7-IML-1)

    International Nuclear Information System (INIS)

    Buecker, D.H.

    1992-01-01

    The experiment is part of a radiobiological space research program to obtain experimental data on the biological effectiveness of the structured component of cosmic radiation during spaceflight. In this proposed experiment, Carausius morosus embryos of different ages will develop under spaceflight conditions. The experiment is designed to determine the influence of galactic heavy ions of very high energy deposition in microgravity on developmental processes of different radiation sensitivity and regenerative capacity. Layers of Carausius morosus eggs are sandwiched between different track detectors (cellulose nitrate, CR39). This method allows the localization of the trajectory of each heavy ion in the biological layer and the identification of the site of the penetration inside the egg

  7. Singular perturbations with boundary conditions and the Casimir effect in the half space

    Science.gov (United States)

    Albeverio, S.; Cognola, G.; Spreafico, M.; Zerbini, S.

    2010-06-01

    We study the self-adjoint extensions of a class of nonmaximal multiplication operators with boundary conditions. We show that these extensions correspond to singular rank 1 perturbations (in the sense of Albeverio and Kurasov [Singular Perturbations of Differential Operaters (Cambridge University Press, Cambridge, 2000)]) of the Laplace operator, namely, the formal Laplacian with a singular delta potential, on the half space. This construction is the appropriate setting to describe the Casimir effect related to a massless scalar field in the flat space-time with an infinite conducting plate and in the presence of a pointlike "impurity." We use the relative zeta determinant (as defined in the works of Müller ["Relative zeta functions, relative determinants and scattering theory," Commun. Math. Phys. 192, 309 (1998)] and Spreafico and Zerbini ["Finite temperature quantum field theory on noncompact domains and application to delta interactions," Rep. Math. Phys. 63, 163 (2009)]) in order to regularize the partition function of this model. We study the analytic extension of the associated relative zeta function, and we present explicit results for the partition function and for the Casimir force.

  8. Time-Accurate Unsteady Pressure Loads Simulated for the Space Launch System at Wind Tunnel Conditions

    Science.gov (United States)

    Alter, Stephen J.; Brauckmann, Gregory J.; Kleb, William L.; Glass, Christopher E.; Streett, Craig L.; Schuster, David M.

    2015-01-01

    A transonic flow field about a Space Launch System (SLS) configuration was simulated with the Fully Unstructured Three-Dimensional (FUN3D) computational fluid dynamics (CFD) code at wind tunnel conditions. Unsteady, time-accurate computations were performed using second-order Delayed Detached Eddy Simulation (DDES) for up to 1.5 physical seconds. The surface pressure time history was collected at 619 locations, 169 of which matched locations on a 2.5 percent wind tunnel model that was tested in the 11 ft. x 11 ft. test section of the NASA Ames Research Center's Unitary Plan Wind Tunnel. Comparisons between computation and experiment showed that the peak surface pressure RMS level occurs behind the forward attach hardware, and good agreement for frequency and power was obtained in this region. Computational domain, grid resolution, and time step sensitivity studies were performed. These included an investigation of pseudo-time sub-iteration convergence. Using these sensitivity studies and experimental data comparisons, a set of best practices to date have been established for FUN3D simulations for SLS launch vehicle analysis. To the author's knowledge, this is the first time DDES has been used in a systematic approach and establish simulation time needed, to analyze unsteady pressure loads on a space launch vehicle such as the NASA SLS.

  9. Modular Hamiltonians for deformed half-spaces and the averaged null energy condition

    Science.gov (United States)

    Faulkner, Thomas; Leigh, Robert G.; Parrikar, Onkar; Wang, Huajia

    2016-09-01

    We study modular Hamiltonians corresponding to the vacuum state for deformed half-spaces in relativistic quantum field theories on {{R}}^{1,d-1} . We show that in addition to the usual boost generator, there is a contribution to the modular Hamiltonian at first order in the shape deformation, proportional to the integral of the null components of the stress tensor along the Rindler horizon. We use this fact along with monotonicity of relative entropy to prove the averaged null energy condition in Minkowski space-time. This subsequently gives a new proof of the Hofman-Maldacena bounds on the parameters appearing in CFT three-point functions. Our main technical advance involves adapting newly developed perturbative methods for calculating entanglement entropy to the problem at hand. These methods were recently used to prove certain results on the shape dependence of entanglement in CFTs and here we generalize these results to excited states and real time dynamics. We also discuss the AdS/CFT counterpart of this result, making connection with the recently proposed gravitational dual for modular Hamiltonians in holographic theories.

  10. Space station needs, attributes and architectural options. Volume 4, task 2 and 3: Mission implementation and cost

    Science.gov (United States)

    1983-01-01

    An overview of the basic space station infrastructure is presented. A strong case is made for the evolution of the station using the basic Space Transportation System (STS) to achieve a smooth transition and cost effective implementation. The integrated logistics support (ILS) element of the overall station infrastructure is investigated. The need for an orbital transport system capability that is the key to servicing and spacecraft positioning scenarios and associated mission needs is examined. Communication is also an extremely important element and the basic issue of station autonomy versus ground support effects the system and subsystem architecture.

  11. Predicting temperature and moisture distributions in conditioned spaces using the zonal approach

    Energy Technology Data Exchange (ETDEWEB)

    Mendonca, K.C. [Parana Pontifical Catholic Univ., Curitiba (Brazil); Wurtz, E.; Inard, C. [La Rochelle Univ., La Rochelle, Cedex (France). LEPTAB

    2005-07-01

    Moisture interacts with building elements in a number of different ways that impact upon building performance, causing deterioration of building materials, as well as contributing to poor indoor air quality. In humid climates, moisture represents one of the major loads in conditioned spaces. It is therefore important to understand and model moisture transport accurately. This paper discussed an intermediate zonal approach to building a library of data in order to predict whole hygrothermal behavior in conditioned rooms. The zonal library included 2 models in order to consider building envelope moisture buffering effects as well as taking into account the dynamic aspect of jet airflow in the zonal method. The zonal library was then applied to a case study to show the impact of external humidity on the whole hygrothermal performance of a room equipped with a vertical fan-coil unit. The proposed theory was structured into 3 groups representing 3 building domains: indoor air; envelope; and heating, ventilation and air conditioning (HVAC) systems. The indoor air sub-model related to indoor air space, where airflow speed was considered to be low. The envelope sub-model related to the radiation exchanges between the envelope and its environment as well as to the heat and mass transfers through the envelope material. The HVAC system sub-model referred to the whole system including equipment, control and specific airflow from the equipment. All the models were coupled into SPARK, where the resulting set of non-linear equations were solved simultaneously. A case study of a large office conditioned by a vertical fan-coil unit with a rectangular air supply diffuser was presented. Details of the building's external and internal environment were provided, as well as convective heat and mass transfer coefficients and temperature distributions versus time. Results of the study indicated that understanding building material moisture buffering effects is as important as

  12. Design of teletherapy facility: effect of space and occupancy on the material cost

    International Nuclear Information System (INIS)

    Dash Sharma, P.K.; Janakiraman, G.; Shirva, V.K.

    2000-01-01

    In this paper, the material cost involved by making the room spacious, orientation of the layout with regards to occupancy around the installation, for 15 MV accelerator and telecobalt facility has been worked out. Here, the cost of RCC (2.35 gm/cc), which is generally used as shielding material is only considered and not the cost of other materials, transportation and labour. This paper may be useful for users to optimise the plan so as to reduce the cost of construction

  13. Evaluation of Costs in Asparagus Production in Relation to Different Technological Processes in Conditions of Slovak Republic

    Directory of Open Access Journals (Sweden)

    Patrik Burg

    2014-01-01

    Full Text Available This study deals with analysis structure of cost on the production of asparagus in relation to three different technological processes in conditions of Slovak Republic. Obtained results can be used as a template to prepare budgets and make production decisions to estimate potential returns and to analyze investment and financial analysis decisions in the asparagus cultivation. Production practices used in the budget are based on typical practices for asparagus in this country. From the analysis of the cost structure of assessed variants different technological procedures follows that the largest share of the costs fall to purchased material and labor.

  14. The cost risk implementation on design-build project of integrated public spaces child friendly in capital of Jakarta

    Science.gov (United States)

    Mardiaman, Mubarok, Abdul

    2017-11-01

    Jakarta area of 662.33 km2 with a population of 10,075,030 inhabitants and green open spaces 9.98%. The Jakarta government built a child-friendly integrated open space as facilities for playing. Providing of facilities was hoped suitable with time, cost, quality, accountability and proper financial governance. Based on the PU ministerial regulation number 19/PRT/M/2015 on the standards and guidelines for procurement the design and construction work on the integrated build and the PU ministerial regulation No. 07/PRT/M/2011 on standards and guidelines for procurement of construction works and consulting services of public works and the ministry of housing. RPTRA development at 123 locations in Jakarta was implemented base on the contract of design and build. The design study was influenced by the cost elements; the main strength (expert), skilled personnel, support personnel, major equipment and support. The construction fee relies on; expert implementation, hardware implementation, preparation work, land, buildings, courtyards, fences, complementary and governance capabilities for human resources in completing the construction activities to minimize the cost risk. Montecarlo simulations was conducted to determine the average unit price, model and analyze systems. In the cost contract, the percentage of design work stipulated 2.5%, build 97.5%. Base on regulation the minister of public work for design work cost 2.72%, build 97.28%. Then, actual cost for design 2.67% and build 97.33%. From the three reference was shown that there are differentiation one another. The acceleration of planning able to make the cost and time more efficient that impact on the implementation margin.

  15. COTS low-cost 622-Mb/s free-space laser communications link for short-distance commercial applications

    Science.gov (United States)

    Morrison, Kenneth A.

    2000-05-01

    The results from a low cost 622 Mb/s, free-space laser communication link operating at 850 nm for short distance commercial applications is presented. The test results demonstrate the use of a free-space laser communications transceiver for building to building applications such as LAN, WAN and ATM operations, etc. This illustrates the potential for wide-use commercial computer network applications. The transceiver is constructed of commercial off-the-shelf materials for the development of a low-cost laser communications data link. The test system configuration utilizes standard Personal Computers with network cards and signal conversion cards for the copper to optical medical conversion. These tests precede the development of an increased data rate device operating at 2.5 Gb/s.

  16. Highly reusable space transportation: Approaches for reducing ETO launch costs to $100 - $200 per pound of payload

    Science.gov (United States)

    Olds, John R.

    1995-01-01

    The Commercial Space Transportation Study (CSTS) suggests that considerable market expansion in earth-to-orbit transportation would take place if current launch prices could be reduced to around $400 per pound of payload. If these low prices can be achieved, annual payload delivered to low earth orbit (LEO) is predicted to reach 6.7 million pounds. The primary market growth will occur in communications, government missions, and civil transportation. By establishing a cost target of $100-$200 per pound of payload for a new launch system, the Highly Reusable Space Transportation (HRST) program has clearly set its sights on removing the current restriction on market growth imposed by today's high launch costs. In particular, achieving the goal of $100-$200 per pound of payload will require significant coordinated efforts in (1) marketing strategy development, (2) business planning, (3) system operational strategy, (4) vehicle technical design, and (5) vehicle maintenance strategy.

  17. The Effect of Infrastructure Sharing in Estimating Operations Cost of Future Space Transportation Systems

    Science.gov (United States)

    Sundaram, Meenakshi

    2005-01-01

    NASA and the aerospace industry are extremely serious about reducing the cost and improving the performance of launch vehicles both manned or unmanned. In the aerospace industry, sharing infrastructure for manufacturing more than one type spacecraft is becoming a trend to achieve economy of scale. An example is the Boeing Decatur facility where both Delta II and Delta IV launch vehicles are made. The author is not sure how Boeing estimates the costs of each spacecraft made in the same facility. Regardless of how a contractor estimates the cost, NASA in its popular cost estimating tool, NASA Air force Cost Modeling (NAFCOM) has to have a method built in to account for the effect of infrastructure sharing. Since there is no provision in the most recent version of NAFCOM2002 to take care of this, it has been found by the Engineering Cost Community at MSFC that the tool overestimates the manufacturing cost by as much as 30%. Therefore, the objective of this study is to develop a methodology to assess the impact of infrastructure sharing so that better operations cost estimates may be made.

  18. Space Shuttle Orbiter Wing-Leading-Edge Panel Thermo-Mechanical Analysis for Entry Conditions

    Science.gov (United States)

    Knight, Norman F., Jr.; Song, Kyongchan; Raju, Ivatury S.

    2010-01-01

    Linear elastic, thermo-mechanical stress analyses of the Space Shuttle Orbiter wing-leading-edge panels is presented for entry heating conditions. The wing-leading-edge panels are made from reinforced carbon-carbon and serve as a part of the overall thermal protection system. Three-dimensional finite element models are described for three configurations: integrated configuration, an independent single-panel configuration, and a local lower-apex joggle segment. Entry temperature conditions are imposed and the through-the-thickness response is examined. From the integrated model, it was concluded that individual panels can be analyzed independently since minimal interaction between adjacent components occurred. From the independent single-panel model, it was concluded that increased through-the-thickness stress levels developed all along the chord of a panel s slip-side joggle region, and hence isolated local joggle sections will exhibit the same trend. From the local joggle models, it was concluded that two-dimensional plane-strain models can be used to study the influence of subsurface defects along the slip-side joggle region of these panels.

  19. Latest condition of the steam coal market and outlook for supply cost

    Energy Technology Data Exchange (ETDEWEB)

    Murase, A.

    1988-11-01

    The following factors affecting coal prices are identified: rises in the prices of fuels which compete with coal, especially petroleum; the supply cost of coal; coal supply and demand; the balance of power between sellers and buyers; and foreign exchange rates. Coal supply costs are discussed. 5 figs.

  20. Programmable Ultra Lightweight System Adaptable Radio (PULSAR) Low Cost Telemetry - Access from Space Advanced Technologies or Down the Middle

    Science.gov (United States)

    Sims. Herb; Varnavas, Kosta; Eberly, Eric

    2013-01-01

    Software Defined Radio (SDR) technology has been proven in the commercial sector since the early 1990's. Today's rapid advancement in mobile telephone reliability and power management capabilities exemplifies the effectiveness of the SDR technology for the modern communications market. In contrast, presently qualified satellite transponder applications were developed during the early 1960's space program. Programmable Ultra Lightweight System Adaptable Radio (PULSAR, NASA-MSFC SDR) technology revolutionizes satellite transponder technology by increasing data through-put capability by, at least, an order of magnitude. PULSAR leverages existing Marshall Space Flight Center SDR designs and commercially enhanced capabilities to provide a path to a radiation tolerant SDR transponder. These innovations will (1) reduce the cost of NASA Low Earth Orbit (LEO) and Deep Space transponders, (2) decrease power requirements, and (3) a commensurate volume reduction. Also, PULSAR increases flexibility to implement multiple transponder types by utilizing the same hardware with altered logic - no analog hardware change is required - all of which can be accomplished in orbit. This provides high capability, low cost, transponders to programs of all sizes. The final project outcome would be the introduction of a Technology Readiness Level (TRL) 7 low-cost CubeSat to SmallSat telemetry system into the NASA Portfolio.

  1. Technology Estimating 2: A Process to Determine the Cost and Schedule of Space Technology Research and Development

    Science.gov (United States)

    Cole, Stuart K.; Wallace, Jon; Schaffer, Mark; May, M. Scott; Greenberg, Marc W.

    2014-01-01

    As a leader in space technology research and development, NASA is continuing in the development of the Technology Estimating process, initiated in 2012, for estimating the cost and schedule of low maturity technology research and development, where the Technology Readiness Level is less than TRL 6. NASA' s Technology Roadmap areas consist of 14 technology areas. The focus of this continuing Technology Estimating effort included four Technology Areas (TA): TA3 Space Power and Energy Storage, TA4 Robotics, TA8 Instruments, and TA12 Materials, to confine the research to the most abundant data pool. This research report continues the development of technology estimating efforts completed during 2013-2014, and addresses the refinement of parameters selected and recommended for use in the estimating process, where the parameters developed are applicable to Cost Estimating Relationships (CERs) used in the parametric cost estimating analysis. This research addresses the architecture for administration of the Technology Cost and Scheduling Estimating tool, the parameters suggested for computer software adjunct to any technology area, and the identification of gaps in the Technology Estimating process.

  2. NASA X-Ray Observatory Completes Tests Under Harsh Simulated Space Conditions

    Science.gov (United States)

    1998-07-01

    NASA's most powerful X-ray observatory has successfully completed a month-long series of tests in the extreme heat, cold, and airless conditions it will encounter in space during its five-year mission to shed new light on some of the darkest mysteries of the universe. The Advanced X-ray Astrophysics Facility was put through the rigorous testing as it was alternately heated and cooled in a special vacuum chamber at TRW Space and Electronics Group in Redondo Beach, Calif., NASA's prime contractor for the observatory. "Successful completion of thermal vacuum testing marks a significant step in readying the observatory for launch aboard the Space Shuttle in January," said Fred Wojtalik, manager of the Observatory Projects Office at NASA's Marshall Space Flight Center in Huntsville, Ala. "The observatory is a complex, highly sophisticated, precision instrument," explained Wojtalik. "We are pleased with the outcome of the testing, and are very proud of the tremendous team of NASA and contractor technicians, engineers and scientists that came together and worked hard to meet this challenging task." Testing began in May after the observatory was raised into the 60-foot thermal vacuum chamber at TRW. Testing was completed on June 20. During the tests the Advanced X-ray Astrophysics Facility was exposed to 232 degree heat and 195 degree below zero Fahrenheit cold. During four temperature cycles, all elements of the observatory - the spacecraft, telescope, and science instruments - were checked out. Computer commands directing the observatory to perform certain functions were sent from test consoles at TRW to all Advanced X-ray Astrophysics Facility components. A team of contractor and NASA engineers and scientists monitored and evaluated the results. Commands were also sent from, and test data monitored at, the Advanced X-ray Astrophysics Facility Operations Control Center in Cambridge, Mass., as part of the test series. The observatory will be managed and controlled from

  3. The impacts of U.S. withdrawal from the Paris Agreement on the carbon emission space and mitigation cost of China, EU, and Japan under the constraints of the global carbon emission space

    Directory of Open Access Journals (Sweden)

    Han-Cheng Dai

    2017-12-01

    Full Text Available Based on the Computable General Equilibrium (CGE model and scenario analysis, the impacts of the U.S. withdrawal from the Paris Agreement on the carbon emission space and mitigation cost in China, European Union (EU, and Japan are assessed under Nationally Determined Contributions (NDCs and 2 °C scenarios due to the changed emission pathway of the U.S. The results show that, under the condition of constant global cumulative carbon emissions and a fixed burden-sharing scheme among countries, the failure of the U.S. to honor its NDC commitment to different degrees will increase the U.S. carbon emission space and decrease its mitigation cost. However, the carbon emission space of other parties, including China, EU, and Japan, will be reduced and their mitigation costs will be increased. In 2030, under the 2 °C target, the carbon price will increase by 4.4–14.6 US$ t−1 in China, by 9.7–35.4 US$ t−1 in the EU, and by 16.0–53.5 US$ t−1 in Japan. In addition, China, EU, and Japan will incur additional Gross Domestic Production (GDP loss. Under the 2 °C target, the GDP loss of China would increase by US$22.0–71.1 billion (equivalent to 16.4–53.1 US$ per capita, the EU's GDP loss would increase by US$9.4–32.1 billion (equivalent to 20.7–71.1 US$ per capita, and Japan's GDP loss will increase by US$4.1–13.5 billion (equivalent to 34.3–111.6 US$ per capita.

  4. Educational Impacts and Cost-Effectiveness of Conditional Cash Transfer Programs in Developing Countries: A Meta-Analysis

    Science.gov (United States)

    García, Sandra; Saavedra, Juan E.

    2017-01-01

    We meta-analyze for impact and cost-effectiveness 94 studies from 47 conditional cash transfer programs in low- and middle-income countries worldwide, focusing on educational outcomes that include enrollment, attendance, dropout, and school completion. To conceptually guide and interpret the empirical findings of our meta-analysis, we present a…

  5. Individual quality and age but not environmental or social conditions modulate costs of reproduction in a capital breeder.

    Science.gov (United States)

    Debeffe, Lucie; Poissant, Jocelyn; McLoughlin, Philip D

    2017-08-01

    Costs associated with reproduction are widely known to play a role in the evolution of reproductive tactics with consequences to population and eco-evolutionary dynamics. Evaluating these costs as they pertain to species in the wild remains an important goal of evolutionary ecology. Individual heterogeneity, including differences in individual quality (i.e., among-individual differences in traits associated with survival and reproduction) or state, and variation in environmental and social conditions can modulate the costs of reproduction; however, few studies have considered effects of these factors simultaneously. Taking advantage of a detailed, long-term dataset for a population of feral horses (Sable Island, Nova Scotia, Canada), we address the question of how intrinsic (quality, age), environmental (winter severity, location), and social conditions (group size, composition, sex ratio, density) influence the costs of reproduction on subsequent reproduction. Individual quality was measured using a multivariate analysis on a combination of four static and dynamic traits expected to depict heterogeneity in individual performance. Female quality and age interacted with reproductive status of the previous year to determine current reproductive effort, while no effect of social or environmental covariates was found. High-quality females showed higher probabilities of giving birth and weaning their foal regardless of their reproductive status the previous year, while those of lower quality showed lower probabilities of producing foals in successive years. Middle-aged (prime) females had the highest probability of giving birth when they had not reproduced the year before, but no such relationship with age was found among females that had reproduced the previous year, indicating that prime-aged females bear higher costs of reproduction. We show that individual quality and age were key factors modulating the costs of reproduction in a capital breeder but that

  6. Life Science Research in Outer Space: New Platform Technologies for Low-Cost, Autonomous Small Satellite Missions

    Science.gov (United States)

    Ricco, Antonio J.; Parra, Macarena P.; Niesel, David; McGinnis, Michael; Ehrenfreund, Pascale; Nicholson, Wayne; Mancinelli, Rocco; Piccini, Matthew E.; Beasley, Christopher C.; Timucin, Linda R.; hide

    2009-01-01

    We develop integrated instruments and platforms suitable for economical, frequent space access for autonomous life science experiments and processes in outer space. The technologies represented by three of our recent free-flyer small-satellite missions are the basis of a rapidly growing toolbox of miniaturized biologically/biochemically-oriented instrumentation now enabling a new generation of in-situ space experiments. Autonomous small satellites ( 1 50 kg) are less expensive to develop and build than fullsize spacecraft and not subject to the comparatively high costs and scheduling challenges of human-tended experimentation on the International Space Station, Space Shuttle, and comparable platforms. A growing number of commercial, government, military, and civilian space launches now carry small secondary science payloads at far lower cost than dedicated missions; the number of opportunities is particularly large for so-called cube-sat and multicube satellites in the 1 10 kg range. The recent explosion in nano-, micro-, and miniature technologies, spanning fields from telecommunications to materials to bio/chemical analysis, enables development of remarkably capable autonomous miniaturized instruments to accomplish remote biological experimentation. High-throughput drug discovery, point-of-care medical diagnostics, and genetic analysis are applications driving rapid progress in autonomous bioanalytical technology. Three of our recent missions exemplify the development of miniaturized analytical payload instrumentation: GeneSat-1 (launched: December 2006), PharmaSat (launched: May 2009), and O/OREOS (organism/organics exposure to orbital stresses; scheduled launch: May 2010). We will highlight the overall architecture and integration of fluidic, optical, sensor, thermal, and electronic technologies and subsystems to support and monitor the growth of microorganisms in culture in these small autonomous space satellites, including real-time tracking of their culture

  7. More space and improved living conditions in cities with autonomous vehicles

    NARCIS (Netherlands)

    Vleugel, J.M.; Bal, Frans

    2017-01-01

    Many people live in cities today. Many more will do so in future. This increases the demand for space and (space for) transport. Space to expand roads is usually scarce. Building tunnels or elevated bridges is very expensive. Solving one bottleneck creates another bottleneck downstream. More road

  8. More space and improved living conditions in cities with autonomous vehicles

    NARCIS (Netherlands)

    Vleugel, J.M.; Bal, Frans

    2017-01-01

    Many people live in cities today. Many more will do so in future. This increases the demand for space and (space for) transport. Space to expand roads is usually scarce. Building tunnels or elevated bridges is very expensive. Solving one bottleneck creates a next bottleneck downstream. More road

  9. Simulation of tree shade impacts on residential energy use for space conditioning in Sacramento

    Science.gov (United States)

    Simpson, J. R.; McPherson, E. G.

    Tree shade reduces summer air conditioning demand and increases winter heating load by intercepting solar energy that would otherwise heat the shaded structure. We evaluate the magnitude of these effects here for 254 residential properties participating in a utility sponsored tree planting program in Sacramento, California. Tree and building characteristics and typical weather data are used to model hourly shading and energy used for space conditioning for each building for a period of one year. There were an average of 3.1 program trees per property which reduced annual and peak (8 h average from 1 to 9 p.m. Pacific Daylight Time) cooling energy use 153 kWh (7.1%) and 0.08 kW (2.3%) per tree, respectively. Annual heating load increased 0.85 GJ (0.80 MBtu, 1.9%) per tree. Changes in cooling load were smaller, but percentage changes larger, for newer buildings. Averaged over all homes, annual cooling savings of 15.25 per tree were reduced by a heating penalty of 5.25 per tree, for net savings of 10.00 per tree from shade. We estimate an annual cooling penalty of 2.80 per tree and heating savings of 6.80 per tree from reduced wind speed, for a net savings of 4.00 per tree, and total annual savings of 14.00 per tree (43.00 per property). Results are found to be consistent with previous simulations and the limited measurements available.

  10. An economic analysis of space solar power and its cost competitiveness as a supplemental source of energy for space and ground markets

    Science.gov (United States)

    Marzwell, N. I.

    2002-01-01

    Economic Growth has been historically associated with nations that first made use of each new energy source. There is no doubt that Solar Power Satellites is high as a potential energy system for the future. A conceptual cost model of the economics value of space solar power (SSP) as a source of complementary power for in-space and ground applications will be discussed. Several financial analysis will be offered based on present and new technological innovations that may compete with or be complementary to present energy market suppliers depending on various institutional arrangements for government and the private sector in a Global Economy. Any of the systems based on fossil fuels such as coal, oil, natural gas, and synthetic fuels share the problem of being finite resources and are subject to ever-increasing cost as they grow ever more scarce with drastic increase in world population. Increasing world population and requirements from emerging underdeveloped countries will also increase overall demand. This paper would compare the future value of SSP with that of other terrestrial renewable energy in distinct geographic markets within the US, in developing countries, Europe, Asia, and Eastern Europe.

  11. Evaluation of storage and disposal costs for conditioned radioactive waste in several European countries

    International Nuclear Information System (INIS)

    Zaccai, H.

    1990-01-01

    A survey on radioactive waste storage and disposal costs has been performed. In order to proceed to such a cost assessment, a survey has been carried on within various nuclear waste agencies throughout Europe. In addition, in order to collect sufficient related economic data, reference has been made to other available information. The results may be summarized as follows: until disposal sites become available, many countries store low-level waste at costs between 400 and 1 400 ECU/m 3 ; little information is supplied for medium- and high-level waste storage; however, for the projects under way, levels of the order of 100 000 ECU/m 3 for vitrified waste are probable, whereas for medium- and high-level waste these costs are expected to vary from 10 000 to 20 000 ECU/m 3 ; the economic analysis of disposal facilities shows that cost elasticity is high at low capacities both for the surface disposal ( 3 ) and deep burial ( 3 ). The economic benefit that might result from the scaling effect at larger capacities appears to be of little significance; despite the diversity of geological formations and disposal concepts for which economic data were compared, a certain coherence can be detected; thus, for the disposal of low-level waste, costs evolve as a function of site capacity from 2 000 to 6 000 ECU/m 3 for deep burial, and from 1 000 to 3 000 ECU/m 3 for surface disposal or shallow burial. For deep burial of medium- and high-level waste, costs vary as a function of site capacity from 10 000 to 70 000 ECU/m 3 for non-heat-emitting waste, and from 0.4 to 1.4 MECU/m 3 for vitrified waste

  12. Time Accurate Unsteady Pressure Loads Simulated for the Space Launch System at a Wind Tunnel Condition

    Science.gov (United States)

    Alter, Stephen J.; Brauckmann, Gregory J.; Kleb, Bil; Streett, Craig L; Glass, Christopher E.; Schuster, David M.

    2015-01-01

    Using the Fully Unstructured Three-Dimensional (FUN3D) computational fluid dynamics code, an unsteady, time-accurate flow field about a Space Launch System configuration was simulated at a transonic wind tunnel condition (Mach = 0.9). Delayed detached eddy simulation combined with Reynolds Averaged Naiver-Stokes and a Spallart-Almaras turbulence model were employed for the simulation. Second order accurate time evolution scheme was used to simulate the flow field, with a minimum of 0.2 seconds of simulated time to as much as 1.4 seconds. Data was collected at 480 pressure taps at locations, 139 of which matched a 3% wind tunnel model, tested in the Transonic Dynamic Tunnel (TDT) facility at NASA Langley Research Center. Comparisons between computation and experiment showed agreement within 5% in terms of location for peak RMS levels, and 20% for frequency and magnitude of power spectral densities. Grid resolution and time step sensitivity studies were performed to identify methods for improved accuracy comparisons to wind tunnel data. With limited computational resources, accurate trends for reduced vibratory loads on the vehicle were observed. Exploratory methods such as determining minimized computed errors based on CFL number and sub-iterations, as well as evaluating frequency content of the unsteady pressures and evaluation of oscillatory shock structures were used in this study to enhance computational efficiency and solution accuracy. These techniques enabled development of a set of best practices, for the evaluation of future flight vehicle designs in terms of vibratory loads.

  13. The impact of common mental and physical health conditions on days out of role: costs for the individual and society.

    Directory of Open Access Journals (Sweden)

    Corina Benjet

    2013-05-01

    Full Text Available Objective. To estimate the individual and societal costs of common mental and physical health conditions in the Mexican population with regards to the number of days out of role. Materials and methods. 5 826 adults were evaluated in 2001-2002 with the Composite International Diagnostic Interview and the WHO Disability Assessment Schedule. General linear models were used to estimate individuallevel effects. Societal-level effects were estimated with the population attributable risk proportion which takes into account prevalence and comorbidity of disorders. Results. The conditions with the strongest individual-level effects were major depression, post-traumatic stress disorder and bipolar disorder. The strongest societal-level effects were associated with major depression, pain, insomnia and cardiovascular conditions. Conclusion. The findings suggest the importance of investing in mental health expenditure to a level commensurate with the costs to society of mental health disorders.

  14. Solar-assisted heat pump system for cost-effective space heating and cooling

    Energy Technology Data Exchange (ETDEWEB)

    Andrews, J W; Kush, E A; Metz, P D

    1978-03-01

    The use of heat pumps for the utilization of solar energy is studied. Two requirements for a cost-effective system are identified: (1) a special heat pump whose coefficient of performance continues to rise with source temperature over the entire range appropriate for solar assist, and (2) a low-cost collection and storage subsystem able to supply solar energy to the heat pump efficiently at low temperatures. Programs leading to the development of these components are discussed. A solar assisted heat pump system using these components is simulated via a computer, and the results of the simulation are used as the basis for a cost comparison of the proposed system with other solar and conventional systems.

  15. Low-cost space fission power systems utilizing US and former Soviet Union experience and technology

    International Nuclear Information System (INIS)

    Wetch, J.R.; Britt, E.J.; Koester, J.K.; Gunther, N.; Ponomarev-Stepnoi, N.N.; Nikolaev, Y.V.; Nikitin, V.

    1997-01-01

    This report summarizes the author close-quote s approach to space power total economics. In the past 40 years of U.S. government sponsored space nuclear power developments, total economics has received only token consideration. In the real world, nuclear power has had limited acceptance where it provided the enabling capability i.e. isotopes for low power, long life, deep space missions, or reactor power for underwater nuclear submarines. It was also accepted where it was perceived to be more economic. Examples are nuclear reactor powered aircraft carriers, escort vessels and central station power stations. In any case, real and perceived public and environmental safety must always be included into the economic equation. copyright 1997 American Institute of Physics

  16. Transferability of results of cost utility analyses for biologicals in inflammatory conditions for Central and Eastern European countries.

    Science.gov (United States)

    Gulácsi, László; Rencz, Fanni; Péntek, Márta; Brodszky, Valentin; Lopert, Ruth; Hevér, Noémi V; Baji, Petra

    2014-05-01

    Several Central and Eastern European (CEE) countries require cost-utility analyses (CUAs) to support reimbursement formulary listing. However, CUAs informed by local evidence are often unavailable, and the cost-effectiveness of the several currently reimbursed biologicals is unclear. To estimate the cost-effectiveness as multiples of per capita GDP/quality adjusted life years (QALY) of four biologicals (infliximab, etanercept, adalimumab, golimumab) currently reimbursed in six CEE countries in six inflammatory rheumatoid and bowel disease conditions. Systematic literature review of published cost-utility analyses in the selected conditions, using the United Kingdom (UK) as reference country and with study selection criteria set to optimize the transfer of results to the CEEs. Prices in each CEE country were pro-rated against UK prices using purchasing power parity (PPP)-adjusted per capita GDP, and local GDP per capita/QALY ratios estimated. Central and Eastern European countries list prices were 144-333% higher than pro rata prices. Out of 85 CUAs identified by previous systematic literature reviews, 15 were selected as a convenience sample for estimating the cost-effectiveness of biologicals in the CEE countries in terms of per capita GDP/QALY. Per capita GDP/QALY values varied from 0.42 to 6.4 across countries and conditions (Bulgaria: 0.97-6.38; Czech Republic: 0.42-2.76; Hungary: 0.54-3.54; Poland: 0.59-3.90; Romania: 0.77-5.07; Slovakia: 0.55-3.61). While results must be interpreted with caution, calculating pro rata (cost-effective) prices and per capita GDP/QALY ratios based on CUAs can aid reimbursement decision-making in the absence of analyses using local data.

  17. Temperature Condition and Spherical Shell Shape Variation of Space Gauge-Alignment Spacecraft

    Directory of Open Access Journals (Sweden)

    V. S. Zarubin

    2016-01-01

    Full Text Available A high precision spherical shell is one of the geometrical shape embodiments of a gaugealignment spacecraft to determine and control a radar channel energy potential of the ground-based complex for the traffic control of space objects. Passive relays of signals and some types of smallsized instrumentation standard reflectors used for radar gauge and alignment have the same shape. Orbits of the considered spacecraft can be either circular with a height of about 1000 km, including those close to the polar, or elliptical with an apogee of up to 2200 km.In case there is no thermal control system in spacecrafts of these types the solar radiation is a major factor to define the thermal state of a spherical shell in the illuminated orbit area. With the shell in fixed position with respect to direction towards the Sun an arising uneven temperature distribution over its surface leads to variation of the spherically ideal shell shape, which may affect the functional characteristics of the spacecraft. The shell rotation about an axis perpendicular to the direction towards the Sun may reduce an unevenness degree of the temperature distribution.The uneven temperature distribution over the spherical shell surface in conditions of the lowEarth space and this unevenness impact on the shell shape variation against its spherical shape can be quantively estimated by the appropriate methods of mathematical modeling using modification of a previously developed mathematical model to describe steady temperature state of such shell on the low-Earth orbit. The paper considers the shell made from a polymeric composite material. Its original spherical shape is defined by rather low internal pressure. It is assumed that equipment in the shell, if any, is quite small-sized. This allows us to ignore its impact on the radiative transfer in the shell cavity. Along with defining the steady temperature distribution over the shell surface at its fixed orientation with respect to

  18. 34 CFR 76.568 - Occupancy and space maintenance costs-restricted rate.

    Science.gov (United States)

    2010-07-01

    ... organization-wide service functions (accounting, payroll, personnel) may be included as general management... costs associated with functions that are not organization-wide must be included with other expenditures... advance by the Secretary. (Authority: 20 U.S.C. 1221e-3(a)(1), 2831(a), 2974(b), and 3474) [59 FR 59584...

  19. Computational Intelligence in Software Cost Estimation: Evolving Conditional Sets of Effort Value Ranges

    OpenAIRE

    Papatheocharous, Efi; Andreou, Andreas S.

    2008-01-01

    In this approach we aimed at addressing the problem of large variances found in available historical data that are used in software cost estimation. Project data is expensive to collect, manage and maintain. Therefore, if we wish to lower the dependence of the estimation to

  20. Wood pellet production costs under Austrian and in comparison to Swedish framework conditions

    NARCIS (Netherlands)

    Obernberger, I.; Thek, G.

    2004-01-01

    Owing to the rapidly increasing importance of pellets as high-quality biomass fuel in Austria and Europe within the last years, many companies, mainly from the wood industry, are thinking of entering this market. The calculation of the production costs before starting a pellet plant is essential for

  1. COST TU0702: Real-time monitoring, surveillance and control of road networks under adverse conditions

    OpenAIRE

    DO, Minh Tan

    2012-01-01

    Contribution au chapitre 1: Pavement surface conditions during adverse weather. Effects of adverse weather conditions on pavement surface conditions are assessed by measuring the effect of water and snow/ice on skid resistance. Skid resistance is defined as the contribution of the road surface to the tire/road friction. Water alters skid resistance by masking the top of the road surface. The tire tread pattern and the road macro/microtexture can help to evacuate the water film. However,...

  2. A low cost automatic detection and ranging system for space surveillance in the medium Earth orbit region and beyond.

    Science.gov (United States)

    Danescu, Radu; Ciurte, Anca; Turcu, Vlad

    2014-02-11

    The space around the Earth is filled with man-made objects, which orbit the planet at altitudes ranging from hundreds to tens of thousands of kilometers. Keeping an eye on all objects in Earth's orbit, useful and not useful, operational or not, is known as Space Surveillance. Due to cost considerations, the space surveillance solutions beyond the Low Earth Orbit region are mainly based on optical instruments. This paper presents a solution for real-time automatic detection and ranging of space objects of altitudes ranging from below the Medium Earth Orbit up to 40,000 km, based on two low cost observation systems built using commercial cameras and marginally professional telescopes, placed 37 km apart, operating as a large baseline stereovision system. The telescopes are pointed towards any visible region of the sky, and the system is able to automatically calibrate the orientation parameters using automatic matching of reference stars from an online catalog, with a very high tolerance for the initial guess of the sky region and camera orientation. The difference between the left and right image of a synchronized stereo pair is used for automatic detection of the satellite pixels, using an original difference computation algorithm that is capable of high sensitivity and a low false positive rate. The use of stereovision provides a strong means of removing false positives, and avoids the need for prior knowledge of the orbits observed, the system being able to detect at the same time all types of objects that fall within the measurement range and are visible on the image.

  3. LIFE experiment: isolation of cryptoendolithic organisms from Antarctic colonized sandstone exposed to space and simulated Mars conditions on the international space station.

    Science.gov (United States)

    Scalzi, Giuliano; Selbmann, Laura; Zucconi, Laura; Rabbow, Elke; Horneck, Gerda; Albertano, Patrizia; Onofri, Silvano

    2012-06-01

    Desiccated Antarctic rocks colonized by cryptoendolithic communities were exposed on the International Space Station (ISS) to space and simulated Mars conditions (LiFE-Lichens and Fungi Experiment). After 1.5 years in space samples were retrieved, rehydrated and spread on different culture media. Colonies of a green alga and a pink-coloured fungus developed on Malt-Agar medium; they were isolated from a sample exposed to simulated Mars conditions beneath a 0.1 % T Suprasil neutral density filter and from a sample exposed to space vacuum without solar radiation exposure, respectively. None of the other flight samples showed any growth after incubation. The two organisms able to grow were identified at genus level by Small SubUnit (SSU) and Internal Transcribed Spacer (ITS) rDNA sequencing as Stichococcus sp. (green alga) and Acarospora sp. (lichenized fungal genus) respectively. The data in the present study provide experimental information on the possibility of eukaryotic life transfer from one planet to another by means of rocks and of survival in Mars environment.

  4. Successive and discrete spaced conditioning in active avoidance learning in young and aged zebrafish.

    Science.gov (United States)

    Yang, Peng; Kajiwara, Riki; Tonoki, Ayako; Itoh, Motoyuki

    2018-05-01

    We designed an automated device to study active avoidance learning abilities of zebrafish. Open source tools were used for the device control, statistical computing, and graphic outputs of data. Using the system, we developed active avoidance tests to examine the effects of trial spacing and aging on learning. Seven-month-old fish showed stronger avoidance behavior as measured by color preference index with discrete spaced training as compared to successive spaced training. Fifteen-month-old fish showed a similar trend, but with reduced cognitive abilities compared with 7-month-old fish. Further, in 7-month-old fish, an increase in learning ability during trials was observed with discrete, but not successive, spaced training. In contrast, 15-month-old fish did not show increase in learning ability during trials. Therefore, these data suggest that discrete spacing is more effective for learning than successive spacing, with the zebrafish active avoidance paradigm, and that the time course analysis of active avoidance using discrete spaced training is useful to detect age-related learning impairment. Copyright © 2017 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

  5. Method for Cost-Benefit Analysis of Improved Indoor Climate Conditions and Reduced Energy Consumption in Office Buildings

    Directory of Open Access Journals (Sweden)

    Viktoras Dorosevas

    2013-09-01

    Full Text Available Indoor climate affects health and productivity of the occupants in office buildings, yet in many buildings of this type indoor climate conditions are not well-controlled due to insufficient heating or cooling capacity, high swings of external or internal heat loads, improper control or operation of heating, ventilation and air conditioning (HVAC equipment, etc. However, maintenance of good indoor environmental conditions in buildings requires increased investments and possible higher energy consumption. This paper focuses on the relation between investment costs for retrofitting HVAC equipment as well as decreased energy use and improved performance of occupants in office buildings. The cost-benefit analysis implementation algorithm is presented in this paper, including energy survey of the building, estimation of occupants dissatisfied by key indoor climate indicators using questionnaire survey and measurements. Technique for Order Preference by Similarity to Ideal Solution (TOPSIS analysis is used in the proposed method for data processing. A case study of an office building is presented in order to introduce an application example of the proposed method. Results of the study verify the applicability of the proposed algorithm and TOPSIS analysis as a practical tool for office building surveys in order to maximize productivity by means of cost efficient technical building retrofitting solutions.

  6. On the necessary conditions of the regular minimum of the scale factor of the co-moving space

    International Nuclear Information System (INIS)

    Agakov, V.G.

    1980-01-01

    In the framework of homogeneous cosmologic model studied is the behaviour of the comoving space element volume filled with barotropous medium, deprived of energy fluxes. Presented are the necessary conditions at which a regular final minimum of the scale factor of the co-mowing space may take place. It is found that to carry out the above minimum at values of cosmological constant Λ <= 0 the presence of two from three anisotropy factors is necessary. Anisotropy of space deformation should be one of these factors. In case of Λ <= 0 the regular minimum is also possible if all three factors of anisotropy are equal to zero. However if none of the factors of Fsub(i), Asub(ik) anisotropy is equal to zero, the presence of deformation space anisotropy is necessary for final regular minimum appearance

  7. Can crawl space temperature and moisture conditions be calculated with a whole-building hygrothermal simulation tool?

    DEFF Research Database (Denmark)

    Vanhoutteghem, Lies; Morelli, Martin; Sørensen, Lars Schiøtt

    2017-01-01

    of measurements was compared with simulations of temperature and moisture condition in the floor structure and crawl space. The measurements showed that the extra 50 mm insulation placed below the beams reduced moisture content in the beams below 20 weight% all year. A reasonable agreement between......The hygrothermal behaviour of an outdoor ventilated crawl space with two different designs of the floor structure was investigated. The first design had 250 mm insulation and visible wooden beams towards the crawl space. The second design had 300 mm insulation and no visible wooden beams. One year...... the measurements and simulations was found; however, the evaporation from the soil was a dominant parameter affecting the hygrothermal response in the crawl space and floor structure....

  8. Capability of space-spectral analysis used for studying underground nuclear explosions effect on ground surface condition

    International Nuclear Information System (INIS)

    Melent'ev, M.I.; Velikanov, A.E.

    2003-01-01

    The article describes the results of the work of study of the influence underground nucleus blasts (UNB) on condition of the day surface of the site Balapan on the territory of Semipalatinsk Test Site using materials of remote space sensing. The estimation of the cosmic spectral analysis information density is given for revealing the post-explosive geo- dynamic processes. (author)

  9. Control of systems with costs related to switching: applications to air-condition systems

    DEFF Research Database (Denmark)

    Thybo (Deng), Honglian; Larsen, Lars Finn Sloth; Stoustrup, Jakob

    2009-01-01

    The objective of this paper is to investigate a low complexity method for controlling systems with binary inputs that have costs related to switching. The control objective for this type of systems is often a trade off between the deviation from the reference and the number of switches (weariness...... energy efficiency etc.). For such systems a steady state solution might never be attained, but rather the optimal behavior might be constituted by a limit cycle. In this paper we consider the problem of finding and controlling the system towards an optimal limit cycle. A low complexity approach giving...

  10. MODERN APPROACHES TO INTELLECTUAL PROPERTY COST ESTIMATION UNDER CRISIS CONDITIONS FROM CONSUMER QUALITY PRESERVATION VIEWPOINT

    Directory of Open Access Journals (Sweden)

    I. N. Alexandrov

    2011-01-01

    Full Text Available Various intellectual property (IP estimation approaches and innovations in this field are discussed. Problem situations and «bottlenecks» in the economic mechanism of transformation of innovations into useful products and services are defined. Main international IP evaluation methods are described, particular attention being paid to «Quick Inside» program defined as latest generation global expert system. IP income and expense evaluation methods used in domestic practice are discussed. Possibility of using the Black-Scholes optional model to estimate costs of non-material assets is studied.

  11. Cost and sensitivity of restricted active-space calculations of metal L-edge X-ray absorption spectra.

    Science.gov (United States)

    Pinjari, Rahul V; Delcey, Mickaël G; Guo, Meiyuan; Odelius, Michael; Lundberg, Marcus

    2016-02-15

    The restricted active-space (RAS) approach can accurately simulate metal L-edge X-ray absorption spectra of first-row transition metal complexes without the use of any fitting parameters. These characteristics provide a unique capability to identify unknown chemical species and to analyze their electronic structure. To find the best balance between cost and accuracy, the sensitivity of the simulated spectra with respect to the method variables has been tested for two models, [FeCl6 ](3-) and [Fe(CN)6 ](3-) . For these systems, the reference calculations give deviations, when compared with experiment, of ≤1 eV in peak positions, ≤30% for the relative intensity of major peaks, and ≤50% for minor peaks. When compared with these deviations, the simulated spectra are sensitive to the number of final states, the inclusion of dynamical correlation, and the ionization potential electron affinity shift, in addition to the selection of the active space. The spectra are less sensitive to the quality of the basis set and even a double-ζ basis gives reasonable results. The inclusion of dynamical correlation through second-order perturbation theory can be done efficiently using the state-specific formalism without correlating the core orbitals. Although these observations are not directly transferable to other systems, they can, together with a cost analysis, aid in the design of RAS models and help to extend the use of this powerful approach to a wider range of transition metal systems. © 2015 Wiley Periodicals, Inc.

  12. GPS Users Positioning Errors during Disturbed Near-Earth Space Conditions

    National Research Council Canada - National Science Library

    Afraimovich, E. L; Demyanov, V. V; Tatarinov, P. V; Astafieva, E. I; Zhivetiev, I. V

    2006-01-01

    .... (GPS Solutions, 2003, V7, N2, 109) showed, that during geomagnetic disturbances in the near space deterioration of GNSS operation quality is appeared and, as consequence, reduction of positioning accuracy and occurrence of failures...

  13. Bidirectional reflectance and VIS-NIR spectroscopy of cometary analogues under simulated space conditions

    Science.gov (United States)

    Jost, Bernhard; Pommerol, Antoine; Poch, Olivier; Yoldi, Zuriñe; Fornasier, Sonia; Hasselmann, Pedro Henrique; Feller, Clément; Carrasco, Nathalie; Szopa, Cyril; Thomas, Nicolas

    2017-10-01

    This work is intended to be the second publication in a series of papers reporting on the spectro-photometric properties of cometary analogues measured in the laboratory. Herein, we provide in-situ hyperspectral imaging data in the 0.40-2.35 μm range from three sublimation experiments under simulated space conditions in thermal vacuum from samples made of water ice, carbonaceous compounds and complex organic molecules. The dataset is complemented by measurements of the bidirectional reflectance in the visible (750 nm) spectral range before and after sublimation. A qualitative characterization of surface evolution processes is provided as well as a description of morphological changes during the simulation experiment. The aim of these experiments is to mimic the spectrum of comet 67P/Churyumov-Gerasimenko (67P) as acquired by the Rosetta mission by applying sublimation experiments on the mixtures of water ice with a complex organic material (tholins) and carbonaceous compounds (carbon black; activated charcoal) studied in our companion publication (Jost et al., submitted). Sublimation experiments are needed to develop the particular texture (high porosity), expected on the nucleus' surface, which might have a strong influence on spectro-photometric properties. The spectrally best matching mixtures of non volatile organic molecules from Jost et al. (submitted) are mixed with fine grained water ice particles and evolved in a thermal vacuum chamber, in order to monitor the influence of the sublimation process on their spectro-photometric properties. We demonstrate that the way the water ice and the non-volatile constituents are mixed, plays a major role in the formation and evolution of a surface residue mantle as well as having influence on the consolidation processes of the underlying ice. Additionally it results in different activity patterns under simulated insolation cycles. Further we show that the phase curves of samples having a porous surface mantle layer

  14. Renewed Urban Waterfront: Spatial Conditions of a Contemporary Urban Space Typology

    OpenAIRE

    Beate Niemann; Fabian Pramel

    2017-01-01

    The formerly industrially or militarily used Urban Waterfront is a potential area for urban development. Extensive interventions in the urban space come along with the development of these previously inaccessible areas in the city. The development of the Urban Waterfront in the European City is not subject to any recognizable urban paradigm. In this study, the development of the Urban Waterfront as a new urban space typology is analyzed by case studies of Urban Waterfront developments in Euro...

  15. Large area, low cost space solar cells with optional wraparound contacts

    Science.gov (United States)

    Michaels, D.; Mendoza, N.; Williams, R.

    1981-01-01

    Design parameters for two large area, low cost solar cells are presented, and electron irradiation testing, thermal alpha testing, and cell processing are discussed. The devices are a 2 ohm-cm base resistivity silicon cell with an evaporated aluminum reflector produced in a dielectric wraparound cell, and a 10 ohm-cm silicon cell with the BSF/BSR combination and a conventional contact system. Both cells are 5.9 x 5.9 cm and require 200 micron thick silicon material due to mission weight constraints. Normalized values for open circuit voltage, short circuit current, and maximum power calculations derived from electron radiation testing are given. In addition, thermal alpha testing values of absorptivity and emittance are included. A pilot cell processing run produced cells averaging 14.4% efficiencies at AMO 28 C. Manufacturing for such cells will be on a mechanized process line, and the area of coverslide application technology must be considered in order to achieve cost effective production.

  16. A multilevel cost-space approach to solving the balanced long transportation problem

    Science.gov (United States)

    Cavanaugh, Kevin J.; Henson, Van Emden

    1993-01-01

    We develop a multilevel scheme for solving the balanced long transportation problem, that is, given a set (c(sub kj)) of shipping costs from a set of M supply nodes S(sub k) to a set of N demand nodes D(sub j), we seek to find a set of flows, (x(sub kj)), that minimizes the total cost Sigma(sub k=1)(exp M) Sigma(sub j=1)(exp N) x(sub kj)c(sub kj). We require that the problem be balanced, that is, the total demand must equal the total supply. Solution techniques for this problem are well known from optimization and linear programming. We examine this problem, however, in order to develop principles that can then be applied to more intractible problems of optimization. We develop a multigrid scheme for solving the problem, defining the grids, relaxation, and intergrid operators. Numerical experimentation shows that this line of research may prove fruitful. Further research directions are suggested.

  17. High Speed, Low Cost Telemetry Access from Space Development Update on Programmable Ultra Lightweight System Adaptable Radio (PULSAR)

    Science.gov (United States)

    Simms, William Herbert, III; Varnavas, Kosta; Eberly, Eric

    2014-01-01

    Software Defined Radio (SDR) technology has been proven in the commercial sector since the early 1990's. Today's rapid advancement in mobile telephone reliability and power management capabilities exemplifies the effectiveness of the SDR technology for the modern communications market. In contrast, the foundations of transponder technology presently qualified for satellite applications were developed during the early space program of the 1960's. Conventional transponders are built to a specific platform and must be redesigned for every new bus while the SDR is adaptive in nature and can fit numerous applications with no hardware modifications. A SDR uses a minimum amount of analog / Radio Frequency (RF) components to up/down-convert the RF signal to/from a digital format. Once the signal is digitized, all processing is performed using hardware or software logic. Typical SDR digital processes include; filtering, modulation, up/down converting and demodulation. NASA Marshall Space Flight Center (MSFC) Programmable Ultra Lightweight System Adaptable Radio (PULSAR) leverages existing MSFC SDR designs and commercial sector enhanced capabilities to provide a path to a radiation tolerant SDR transponder. These innovations (1) reduce the cost of NASA Low Earth Orbit (LEO) and Deep Space standard transponders, (2) decrease power requirements, and (3) commensurately reduce volume. A second pay-off is the increased SDR flexibility by allowing the same hardware to implement multiple transponder types simply by altering hardware logic - no change of hardware is required - all of which will ultimately be accomplished in orbit. Development of SDR technology for space applications will provide a highly capable, low cost transponder to programs of all sizes. The MSFC PULSAR Project results in a Technology Readiness Level (TRL) 7 low-cost telemetry system available to Smallsat and CubeSat missions, as well as other platforms. This paper documents the continued development and

  18. The contribution of woody plant materials on the several conditions in a space environment

    Science.gov (United States)

    Tomita-Yokotani, Kaori; Baba, Keiichi; Suzuki, Toshisada; Kimura, Shunta; Sato, Seigo; Katoh, Hiroshi; Abe, Yusuke; Katayama, Takeshi

    Woody plant materials have several utilization elements in our habitation environment on earth. The studies of woody plants under a space-environment in the vegetable kingdom have a high contribution to the study of various and exotic environmental responses, too. Woody plants can produce an excess oxygen, woody materials for the living cabin, and provide a biomass by cultivating crops and other species of creatures. Tree material would become to be a tool in closed bio-ecosystems such as an environment in a space. We named the trees used as material for the experiment related to space environments “CosmoBon”, small tree bonsai. Japanese cherry tree, “Sakura”, is famous and lovely tree in Japan. One species of “Sakura”, “Mamezakura, Prunus incisa”, is not only lovely tree species, but also suitable tree for the model tree of our purpose. The species of Prunus incisa is originally grown in volcano environment. That species of Sakura is originally grown on Mt. Fuji aria, oligotrophic place. We will try to build the best utilization usage of woody plant under the space environment by “Mamezakura” as a model tree. Here, we will show the importance of uniformity of materials when we will use the tree materials in a space environment. We will also discuss that tree has a high possibility of utilization under the space environments by using our several results related to this research.

  19. Space mutagenic effects on cistanche deserticola seed viability and parasitic condition

    International Nuclear Information System (INIS)

    Xu Rong; Zhou Feng; Yu Jing; Chen Jun; Sun Suqin; Liu Yougang; Liu Tongning

    2009-01-01

    The seeds of Cistanche deserticola which from a single plant with fine properties were carried to the space by the recoverable experiment satellite 'Shijian No.8'. After space loading, the seed viability and characters of infrared spectroscopy were analyzed and then planted to observe and investigate the variation and heredity. The results showed that compared to the control group, the seed viability and germination rate increased observably after space loading. As well, the plants grew much healthier at the seedling stage. The results indicated that space loading has obvious promote effects on the seed viability, germination rate and disease resistance of Cistanche deserticola. The analysis results of infrared spectroscopy showed the contents of protein and carbohydrate were increased distinctly and the contents of oil or fat reduced somewhat in the seeds after space loading. The intensity ratio between characteristic absorption peak of protein and characteristic absorption peak of fat (I 1625 /I 1745 ) were increased from 1.07 to 1.16, which could be related to the enhancement of seed viability and the reduction of germination restraint substances. It could be concluded that microgravity and intense radiation in the space caused seed viability and material metabolism change. (authors)

  20. Recent results from CEC cost sharing research programme on LWR fuel behaviour under accident conditions

    International Nuclear Information System (INIS)

    Fairbairn, S.A.

    1983-01-01

    The present structure and intentions of the CEC sponsored cost sharing programme for LWR safety research are outlined. Detailed results are reported for two projects from this programme. The first project concerns experimental data on the thermohydraulic effects of flow diversion around ballooned fuel rods. Data are presented on single and two phase heat transfer in an electrically heated rod bundle. Detailed photographic data on droplet behaviour are also given. The second project is an investigation of the effects of zircaloy oxidation on rewetting during reflood. It is shown that as oxide thickness increases from 1μm to 76μm that rewet rates can increase by up to 40%. A systematic effect of oxidation on rewet temperatures is also noted. (author)

  1. Decoupling dehumidification and cooling for energy saving and desirable space air conditions in hot and humid Hong Kong

    International Nuclear Information System (INIS)

    Lee, W.L.; Chen Hua; Leung, Y.C.; Zhang, Y.

    2012-01-01

    Highlights: ► The combined use of dedicated ventilation and dry cooling (DCDV) system was investigated. ► Investigations were based actual equipment performance data and realistic building and system characteristics. ► DCDV system could save 54% of the annual energy use for air-conditioning. ► DCDV system could better achieve the desired space air conditions. ► DCDV system could decouple dehumidification and cooling. - Abstract: The combined use of dedicated outdoor air ventilation (DV) and dry cooling (DC) air-conditioning system to decouple sensible and latent cooling for desirable space air conditions, better indoor air quality, and energy efficiency is proposed for hot and humid climates like Hong Kong. In this study, the performance and energy saving potential of DCDV system in comparison to conventional systems (constant air volume (CAV) system with and without reheat) for air conditioning of a typical office building in Hong Kong are evaluated. Through hour-by-hour simulations, using actual equipment performance data and realistic building and system characteristics, the cooling load profile, resultant indoor air conditions, condensation at the DC coil, and energy consumptions are calculated and analyzed. The results indicate that with the use of DCDV system, the desirable indoor conditions could be achieved and the annual energy use could be reduced by 54% over CAV system with reheat. The condensate-free characteristic at the DC coil to reduce risk of catching disease could also be realized.

  2. On Probabilistic Alpha-Fuzzy Fixed Points and Related Convergence Results in Probabilistic Metric and Menger Spaces under Some Pompeiu-Hausdorff-Like Probabilistic Contractive Conditions

    OpenAIRE

    De la Sen, M.

    2015-01-01

    In the framework of complete probabilistic metric spaces and, in particular, in probabilistic Menger spaces, this paper investigates some relevant properties of convergence of sequences to probabilistic α-fuzzy fixed points under some types of probabilistic contractive conditions.

  3. Providing better thermal and air quality conditions in school classrooms would be cost-effective

    DEFF Research Database (Denmark)

    Wargocki, Pawel; Wyon, David Peter

    2013-01-01

    codes stipulate that they should be. This is sometimes because financial resources for the maintenance and upgrade of school buildings are inadequate, but it is also because schools are increasingly allowing classroom temperatures to drift above the recommended range of 20–22 °C in warm weather......This paper is an overall summary of research by the authors on how classroom conditions affect the performance of schoolwork by children, motivated by the fact that the thermal and air quality conditions in school classrooms are now almost universally worse than the relevant standards and building...... and allowing outdoor air supply rates to remain so low that carbon dioxide (CO2) levels during school hours exceed 1000 ppm for long periods, in order to conserve energy. The research that is summarized in this paper shows that the indoor environmental consequences of either of these investment-free but ill...

  4. Incorrect modeling of the failure process of minimally repaired systems under random conditions: The effect on the maintenance costs

    International Nuclear Information System (INIS)

    Pulcini, Gianpaolo

    2015-01-01

    This note investigates the effect of the incorrect modeling of the failure process of minimally repaired systems that operates under random environmental conditions on the costs of a periodic replacement maintenance. The motivation of this paper is given by a recently published paper, where a wrong formulation of the expected cost for unit time under a periodic replacement policy is obtained. This wrong formulation is due to the incorrect assumption that the intensity function of minimally repaired systems that operate under random conditions has the same functional form as the failure rate of the first failure time. This produced an incorrect optimization of the replacement maintenance. Thus, in this note the conceptual differences between the intensity function and the failure rate of the first failure time are first highlighted. Then, the correct expressions of the expected cost and of the optimal replacement period are provided. Finally, a real application is used to measure how severe can be the economical consequences caused by the incorrect modeling of the failure process.

  5. Existence Results for Differential Inclusions with Nonlinear Growth Conditions in Banach Spaces

    Directory of Open Access Journals (Sweden)

    Messaoud Bounkhel

    2013-01-01

    Full Text Available In the Banach space setting, the existence of viable solutions for differential inclusions with nonlinear growth; that is, ẋ(t∈F(t,x(t a.e. on I, x(t∈S, ∀t∈I, x(0=x0∈S, (*, where S is a closed subset in a Banach space , I=[0,T], (T>0, F:I×S→, is an upper semicontinuous set-valued mapping with convex values satisfying F(t,x⊂c(tx+xp, ∀(t,x∈I×S, where p∈ℝ, with p≠1, and c∈C([0,T],ℝ+. The existence of solutions for nonconvex sweeping processes with perturbations with nonlinear growth is also proved in separable Hilbert spaces.

  6. Schwarzian导数,几何条件和Qκ空间%Schwarzian derivative, geometric conditions and Qκ spaces

    Institute of Scientific and Technical Information of China (English)

    周继振

    2012-01-01

    设Ψ:D→Ω是一个单叶函数,利用Schwarzian导数,本文获得了logΨ'属于Qκ空间的一个充要条件.此外,本文运用了一个几何条件来刻画Qκ空间.%For a univalent function Ψ : D → Ω, we study the membership of logψ' to the space QK in terms of the Schwarzian derivative. We also apply a geometric condition to characterize the space QK.

  7. Conditions for order and chaos in the dynamics of a trapped Bose-Einstein condensate in coordinate and energy space

    Science.gov (United States)

    Sakhel, Roger R.; Sakhel, Asaad R.; Ghassib, Humam B.; Balaz, Antun

    2016-03-01

    We investigate numerically conditions for order and chaos in the dynamics of an interacting Bose-Einstein condensate (BEC) confined by an external trap cut off by a hard-wall box potential. The BEC is stirred by a laser to induce excitations manifesting as irregular spatial and energy oscillations of the trapped cloud. Adding laser stirring to the external trap results in an effective time-varying trapping frequency in connection with the dynamically changing combined external+laser potential trap. The resulting dynamics are analyzed by plotting their trajectories in coordinate phase space and in energy space. The Lyapunov exponents are computed to confirm the existence of chaos in the latter space. Quantum effects and trap anharmonicity are demonstrated to generate chaos in energy space, thus confirming its presence and implicating either quantum effects or trap anharmonicity as its generator. The presence of chaos in energy space does not necessarily translate into chaos in coordinate space. In general, a dynamic trapping frequency is found to promote chaos in a trapped BEC. An apparent means to suppress chaos in a trapped BEC is achieved by increasing the characteristic scale of the external trap with respect to the condensate size.

  8. Comparison of SPACE to MARS-KS under SUBO experimental conditions

    International Nuclear Information System (INIS)

    Kim, Min-Gil; Lee, Wonwoong; Lee, Jeong Ik; Bang, Young Seok

    2015-01-01

    To evaluate safety of a Korean Nuclear Power Plant (NPP) MARS-KS code is being used by the Korean regulator. The governing equations of MARS-KS are based on two-phase and two-fluid model. Recently, SPACE (Safety and Performance Analysis CodE for nuclear power plants) was developed by a consortium led by Korea Hydro and Nuclear Power Co., Ltd. (KHNP), which the code is aimed for evaluating the safety of the designed nuclear power plant. The governing equations of SPACE are based on two-phase (liquid and gas phase) three-fluid (continuous liquid, gas and droplet) model. However, MARS-KS and SPACE have different governing equations, as well as model and correlations implemented in two codes. Due to this reason, the authors are studying the difference in the analysis result of SET (Separate Effect Test) of each code.. To compare the SPACE and MARS-KS performances, the authors chose SUBO experiment as the first reference case. Input deck of each code was prepared. The results from the two codes were compared to the experimental data, but due to the lack of information on the uncertainties it is too early to conclude the code performance. However, from the obtained analysis results, some differences between MARS-KS and SPACE are observed. Especially, flow regimes at heated region are considerably different. More detailed analysis of the flow regime and its effect in MARS-KS and SPACE analysis results will be followed in the near future. The heat transfer coefficient and friction factor at the interface and at the wall will be compared with similar method used in this study

  9. The quantum oscillator on complex projective space (Lobachewski space) in a constant magnetic field and the issue of generic boundary conditions

    International Nuclear Information System (INIS)

    Giri, Pulak Ranjan

    2007-01-01

    We perform a one-parameter family of self-adjoint extensions characterized by the parameter ω 0 . This allows us to get generic boundary conditions for the quantum oscillator on N-dimensional complex projective space (CP N ) and on its non-compact version, i.e., Lobachewski space (L N ) in the presence of a constant magnetic field. As a result, we get a family of energy spectra for the oscillator. In our formulation the already known result of this oscillator also belongs to the family. We have also obtained an energy spectrum which preserves all the symmetries (full-hidden symmetry and rotational symmetry) of the oscillator. The method of self-adjoint extensions has also been discussed for a conic oscillator in the presence of the constant magnetic field

  10. Technology Estimating: A Process to Determine the Cost and Schedule of Space Technology Research and Development

    Science.gov (United States)

    Cole, Stuart K.; Reeves, John D.; Williams-Byrd, Julie A.; Greenberg, Marc; Comstock, Doug; Olds, John R.; Wallace, Jon; DePasquale, Dominic; Schaffer, Mark

    2013-01-01

    NASA is investing in new technologies that include 14 primary technology roadmap areas, and aeronautics. Understanding the cost for research and development of these technologies and the time it takes to increase the maturity of the technology is important to the support of the ongoing and future NASA missions. Overall, technology estimating may help provide guidance to technology investment strategies to help improve evaluation of technology affordability, and aid in decision support. The research provides a summary of the framework development of a Technology Estimating process where four technology roadmap areas were selected to be studied. The framework includes definition of terms, discussion for narrowing the focus from 14 NASA Technology Roadmap areas to four, and further refinement to include technologies, TRL range of 2 to 6. Included in this paper is a discussion to address the evaluation of 20 unique technology parameters that were initially identified, evaluated and then subsequently reduced for use in characterizing these technologies. A discussion of data acquisition effort and criteria established for data quality are provided. The findings obtained during the research included gaps identified, and a description of a spreadsheet-based estimating tool initiated as a part of the Technology Estimating process.

  11. A life cycle cost economics model for automation projects with uniformly varying operating costs. [applied to Deep Space Network and Air Force Systems Command

    Science.gov (United States)

    Remer, D. S.

    1977-01-01

    The described mathematical model calculates life-cycle costs for projects with operating costs increasing or decreasing linearly with time. The cost factors involved in the life-cycle cost are considered, and the errors resulting from the assumption of constant rather than uniformly varying operating costs are examined. Parameters in the study range from 2 to 30 years, for project life; 0 to 15% per year, for interest rate; and 5 to 90% of the initial operating cost, for the operating cost gradient. A numerical example is presented.

  12. Calculation and measurement of space charge in MV-size xxtruded cables systems under load conditions

    NARCIS (Netherlands)

    Morshuis, P.H.F.; Bodega, R.; Fabiani, D.; Montanari, G.C.; Dissado, L.A.; Smit, J.J.

    2007-01-01

    A load current in dc high voltage cables results in a temperature drop across the insulation and hence a radial distribution of the insulation conductivity is found. Direct consequence is an accumulation of space charge in the bulk of the nsulation, that may significantly affect its reliability.

  13. A universal mirror wave-mode threshold condition for non-thermal space plasma environments

    Directory of Open Access Journals (Sweden)

    M. P. Leubner

    2002-01-01

    Full Text Available Magnetic fluctuations are recognized in a large variety of space plasmas by increasingly high resolution, in situ observations as mirror wave mode structures. A typical requirement for the excitation of mirror modes is a dominant perpendicular pressure in a high-beta plasma environment. Contrary, we demonstrate from a realistic kinetic analysis how details of the velocity space distributions are of considerable significance for the instability threshold. Introducing the most common characteristics of observed ion and electron distributions by a mixed suprathermal-loss-cone, we derive a universal mirror instability criterion from an energy principle for collisionless plasmas. As a result, the transition from two temperature Maxwellians to realistic non-thermal features provides a strong source for the generation of mirror wave mode activity, reducing drastically the instability threshold. In particular, a number of space-related examples illuminate how the specific structure of the velocity space distribution dominates as a regulating excitation mechanism over the effects related to changes in the plasma parameters.

  14. A necessary flexibility condition for a nondegenerate suspension in Lobachevsky 3-space

    Energy Technology Data Exchange (ETDEWEB)

    Slutskii, D A [S.L. Sobolev Institute for Mathematics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk (Russian Federation)

    2013-08-31

    We show that some combination of the lengths of all edges of the equator of a flexible suspension in Lobachevsky 3-space is equal to zero (each length is taken with a 'plus' or 'minus' sign in this combination). Bibliography: 10 titles.

  15. Dimension elevation in Müntz spaces: A new emergence of the Müntz condition

    KAUST Repository

    Ait-Haddou, Rachid

    2014-01-01

    We show that the limiting polygon generated by the dimension elevation algorithm with respect to the Müntz space span(1,tr1,tr2,trm,. . .), with 0 < r1 < r2 < ⋯ < r m < ⋯ and lim n →∞r n = ∞, over an interval [a, b] ⊂ ] 0

  16. The advanced launch system: Application of total quality management principles to low-cost space transportation system development

    Science.gov (United States)

    Wolfe, M. G.; Rothwell, T. G.; Rosenberg, D. A.; Oliver, M. B.

    Recognizing that a major inhibitor of man's rapid expansion of the use of space is the high cost (direct and induced) of space transportation, the U.S. has embarked on a major national program to radically reduce the cost of placing payloads into orbit while, at the same time, making equally radical improvements inlaunch system operability. The program is entitled "The Advanced Launch System" (ALS) and is a joint Department of Defense/National Aeronautics and Space Administration (DoD/NASA) program which will provide launch capability in the post 2000 timeframe. It is currently in Phase II (System Definition), which began in January 1989, and will serve as a major source of U.S. launch system technology over the next several years. The ALS is characterized by a new approach to space system design, development, and operation. The practices that are being implemented by the ALS are expected to affect the management and technical operation of all future launch systems. In this regard, the two most significant initiatives being implemented on the ALS program are the practices of Total Quality Management (TQM) and the Unified Information System (Unis). TQM is a DoD initiative to improve the quality of the DoD acquisition system, contractor management systems, and the technical disciplines associated with the design, development, and operation of major systems. TQM has been mandated for all new programs and affects the way every group within the system currently does business. In order to implement the practices of TQM, new methods are needed. A program on the scale of the ALS generates vast amounts of information which must be used effectively to make sound decisions. Unis is an information network that will connect all ALS participants throughout all phases of the ALS development. Unis is providing support for project management and system design, and in following phases will provide decision support for launch operations, computer integrated manufacturing, automated

  17. Cost-effectiveness performance analysis of organic Rankine cycle for low grade heat utilization coupling with operation condition

    International Nuclear Information System (INIS)

    Wang, Dongxiang; Ling, Xiang; Peng, Hao

    2013-01-01

    This paper analyzed the influence of working fluids selection and operation conditions on the cost-effectiveness performance and net power output of an ORC for low grade heat utilization. A net power output model has been proposed theoretically and compared with the theoretical data calculated from thermodynamic analysis, exhibiting excellent agreements with the theoretical data. The proposed net power output model theoretically indicates that Jacob number and the ratio of evaporating temperature and heat rejected temperature play essential roles in discriminating the net power output among various working fluids at the same operation condition. For a given condensing and evaporating temperature, it can be concluded theoretically that fluid with low Jacob number will show attractive performance in an ORC. The maximum net power output is determined by the heat source rather than working fluids with a low inlet temperature of heat source. Cost-effectiveness performance analysis reveals that the maximum net power output and the best CEP cannot be achieved at the same time and compromise must be made when choosing the most suitable organic working fluids in different ORC designs. -- Highlights: • A net power output model is proposed and compared with theoretical data. • For fixed operation condition, low Ja fluid shows attractive performance in ORC. • The heat source rather than working fluid determines ORC performance at low T hs,in • The peak W net and best CEP cannot be achieved at the same time, compromise must be made

  18. Assessing the cost of helping: the roles of body condition and oxidative balance in the Seychelles warbler (Acrocephalus sechellensis.

    Directory of Open Access Journals (Sweden)

    Janske van de Crommenacker

    Full Text Available In cooperatively breeding species, helping close relatives may provide important fitness benefits. However, helping can be energetically expensive and may result in increased generation of reactive oxygen species. Consequently, an oxidant/antioxidant imbalance can lead to higher oxidative stress susceptibility. Given the potential costs of helping, it may be that only individuals with a sufficiently good body condition and/or stable oxidative balance can afford to help. Knowledge about relationships between social status and oxidative balance in cooperatively breeding systems is still limited. Studying these relationships is important for understanding the costs of helping and physiological pressures of reproduction. Here we evaluate the relationship between helping behaviour, body condition and oxidative balance in a wild population of the cooperatively breeding Seychelles warbler (Acrocephalus sechellensis. In this species, some subordinate individuals help dominant birds with the rearing of young, while others refrain from any assistance. We assessed body condition and oxidative parameters of birds of different social status caught during different breeding stages. We found that, prior to breeding, female subordinates that did not subsequently help (non-helpers had significantly lower body condition and higher ROMs (reactive oxygen metabolites than helpers and dominants. During the later stages of breeding, body condition was low in dominants and helpers, but high in non-helpers. Differences in oxidative balance between individuals of different social status were found only during nest care: Dominant males occupied with guarding behaviours tended to have relatively high oxidative stress susceptibility. Furthermore, dominant and helper females showed elevated antioxidant capacity (measured as OXY in the weeks just prior to egg-laying, possibly representing a change in their reproductive physiology. The results imply that an individuals

  19. Expose-R experiment on effects of open space condition on survivorship in dormant stages of aquatic invertebrates

    Science.gov (United States)

    Alekseev, Victor; Novikova, Nataliya; Levinskikh, Margarita; Sychev, Vladimir; Yusoff, Fatimah; Azuraidi, Osman

    2012-07-01

    Dormancy protects animals and plants in harsh environmental conditions from months up to hundred years. This phenomenon is perspective for space researches especially for interplanetary missions. Direct experiments in open space BYORYSK supported in principle the fact of survivorship of bacteria, fungi spores, seed of plants and crustacean dormant cysts. Even though the rate of survivorship in long-term treatments was low but good enough to conclude that biological invasion even to Mars is a real danger. As soon as the BYORYSK lunch was made of metal the possibility for resting stages to survive under UV treatment in vacuum without some protection was not clear. To test it an ESA and RSA equipment titled EXPOSE-R was applied. The EXPOSE-R facility was an external facility attached to the outside of the Zvezda Service Module in ISS in the end of November 2008. It had glace windows transparent for UV-radiation and possibility to measure temperature, space- and UV-radiation. Among a number of experiments requiring exposure to the open space environment it had a biological launch containing resting stages of terrestrial and aquatic organisms. These stages included dried ephippia of cladoceran Daphnia magna differentiated on size, dormant eggs of ostracode Eucypris ornate, cysts of fair-shrimp Streptocephalus torvicornis ( all from hemi desert Caspian area) and Artemis salina from salt lake Crimean populations. All dormant stages were kept in transparent to UV plastic bags placed in three layers. After about two years of exposing in open space dormant stages of 3 species A. salina, D. magna, S. torvicornis successfully survived at different scales but in second and third layers only . The highest level of survivorship was found in A. salina cysts. In preliminary land experiments that imitated land EXPOSE imitation of outside space station UV and vacuum conditions survivorship in resting eggs of D .magna, S. torvicornis and E. ornate was tested also. The total UV dose of

  20. Exergy and energy analyses of two different types of PCM based thermal management systems for space air conditioning applications

    International Nuclear Information System (INIS)

    Tyagi, V.V.; Pandey, A.K.; Buddhi, D.; Tyagi, S.K.

    2013-01-01

    Highlights: ► Calcium chloride hexahydrate (CaCl 2 ⋅6H 2 O) as a PCM was used in this study. ► Two different capsulated system (HDPE based panel and balls) were designed. ► The results of CaCl 2 ⋅6H 2 O are very attractive for space air conditioning. ► Energy and exergy analyses for space cooling applications. - Abstract: This communication presents the experimental study of PCM based thermal management systems for space heating and cooling applications using energy and exergy analysis. Two different types of based thermal management system (TMS-I and TMS-II) using calcium chloride hexahydrate as the heat carrier has been designed, fabricated and studied for space heating and cooling applications at a typical climatic zone in India. In the first experimental arrangement the charging of PCM has been carried out with air conditioning system while discharging has been carried out using electric heater for both the thermal management systems. While in the second arrangement the charging of PCM has been carried out by solar energy and the discharging has been carried out by circulating the cooler ambient air during the night time. In the first experiment, TMS-I is found to be more effective than that of TMS-II while it was found to be reverse in the case of second experiment for both the charging and discharging processes not only for energetic but also for the exergetic performances

  1. Common Fixed Point Theorems in Fuzzy Metric Spaces Satisfying -Contractive Condition with Common Limit Range Property

    Directory of Open Access Journals (Sweden)

    Sunny Chauhan

    2013-01-01

    Full Text Available The objective of this paper is to emphasize the role of “common limit range property” to ascertain the existence of common fixed point in fuzzy metric spaces. Some illustrative examples are furnished which demonstrate the validity of the hypotheses and degree of utility of our results. We derive a fixed point theorem for four finite families of self-mappings which can be utilized to derive common fixed point theorems involving any finite number of mappings. As an application to our main result, we prove an integral-type fixed point theorem in fuzzy metric space. Our results improve and extend a host of previously known results including the ones contained in Imdad et al. (2012.

  2. Anomaly matching conditions and the moduli space of supersymmetric gauge theories

    International Nuclear Information System (INIS)

    Dotti, G.; Manohar, A.V.

    1998-01-01

    The structure of the moduli space of N=1 supersymmetric gauge theories is analyzed from an algebraic geometric viewpoint. The connection between the fundamental fields of the ultraviolet theory, and the gauge-invariant composite fields of the infrared theory is explained in detail. The results are then used to prove an anomaly matching theorem. The theorem is used to study anomaly matching for supersymmetric QCD, and can explain all the known anomaly matching results for this case. (orig.)

  3. Estimation of optical attenuation in reduced visibility conditions in different environments across free space optics link

    Czech Academy of Sciences Publication Activity Database

    Dev, K.; Nebuloni, R.; Capsoni, C.; Fišer, Ondřej; Brázda, V.

    2017-01-01

    Roč. 11, č. 12 (2017), s. 1708-1713 ISSN 1751-8725 Institutional support: RVO:68378289 Keywords : light attenuation * optical sensors * free-space optical communication Subject RIV: DG - Athmosphere Sciences, Meteorology OBOR OECD: Meteorology and atmospheric sciences Impact factor: 1.187, year: 2016 http://digital-library.theiet.org/content/journals/10.1049/iet-map.2016.0872

  4. Effect of Ducted HPWH on Space-Conditioning and Water Heating Energy Use -- Central Florida Lab Home

    Energy Technology Data Exchange (ETDEWEB)

    Colon, Carlos [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States); Martin, Eric [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States); Parker, Danny [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States)

    2016-11-01

    The purpose of this research is to investigate the impact of ducted heat pump water heaters (HPWHs) on space conditioning and water heating energy use in residential applications. Two identical HPWHs, each of 60 gallon capacity were tested side by side at the Flexible Residential Test facility (FRTF) laboratories of the Florida Solar Energy Center (FSEC) campus in Cocoa, Florida. The water heating experiments were run in each test house from July 2014 until February 2015.

  5. Effect of Ducted HPWH on Space-Conditioning and Water Heating Energy Use -- Central Florida Lab Home

    Energy Technology Data Exchange (ETDEWEB)

    Colon, Carlos [Florida Solar Energy Center, Cocoa, FL (United States); Martin, Eric [Florida Solar Energy Center, Cocoa, FL (United States); Parker, Danny [Florida Solar Energy Center, Cocoa, FL (United States)

    2016-11-01

    The purpose of this research is to investigate the impact of ducted heat pump water heaters (HPWH's) on space conditioning and water heating energy use in residential applications. Two identical HPWH's, each of 60 gallon capacity were tested side by side at the Flexible Residential Test facility (FRTF) laboratories of the Florida Solar Energy Center (FSEC) campus in Cocoa, Florida. The water heating experiments were run in each test house from July 2014 until February 2015.

  6. Graph-theoretic analysis of discrete-phase-space states for condition change detection and quantification of information

    Science.gov (United States)

    Hively, Lee M.

    2014-09-16

    Data collected from devices and human condition may be used to forewarn of critical events such as machine/structural failure or events from brain/heart wave data stroke. By monitoring the data, and determining what values are indicative of a failure forewarning, one can provide adequate notice of the impending failure in order to take preventive measures. This disclosure teaches a computer-based method to convert dynamical numeric data representing physical objects (unstructured data) into discrete-phase-space states, and hence into a graph (structured data) for extraction of condition change.

  7. ``From seed-to-seed'' experiment with wheat plants under space-flight conditions

    Science.gov (United States)

    Mashinsky, A.; Ivanova, I.; Derendyaeva, T.; Nechitailo, G.; Salisbury, F.

    1994-11-01

    An important goal with plant experiments in microgravity is to achieve a complete life cycle, the ``seed-to-seed experiment''. Some Soviet attempts to reach this goal are described, notably an experiment with the tiny mustard, Arabidopsis thaliana, in the Phyton 3 device on Salyut 7. Normal seeds were produced although yields were reduced and development was delayed. Several other experiments have shown abnormalities in plants grown in space. In recent work, plants of wheat (Triticum aestivum) were studied on the ground and then in a preliminary experiment in space. Biometric indices of vegetative space plants were 2 to 2.5 times lower than those of controls, levels of chlorophyll a and b were reduced (no change in the ratio of the two pigments), carotenoids were reduced, there was a serious imbalance in major minerals, and membrane lipids were reduced (no obvious change in lipid patterns). Following the preliminary studies, an attempt was made with the Svetoblock-M growth unit to grow a super-dwarf wheat cultivar through a life cycle. The experiment lasted 167 d on Mir. Growth halted from about day 40 to day 100, when new shoots appeared. Three heads had appeared in the boot (surrounded by leaves) when plants were returned to earth. One head was sterile, but 28 seeds matured on earth, and most of these have since produced normal plants and seeds. In principle, a seed-to-seed experiment with wheat should be successful in microgravity.

  8. Lumbar hernia: A commonly misevaluated condition of the bilateral costoiliac spaces

    Directory of Open Access Journals (Sweden)

    Yiji Suh

    2017-09-01

    Full Text Available Lumbar hernias develop through the weakening of the posterolateral abdominal wall associated with the Petit's triangle or the Grynfeltt-Lesshaft triangle. Clinicians are generally unfamiliar with the presentation of lumbar hernias, which frequently leads to misdiagnosis and delay of treatment. Prompt failure to diagnose and surgically correct lumbar hernias have resulted in increased morbidity. This review addresses the anatomical and clinical concepts associated with the bilateral costoiliac spaces, which may be implicated in the increased prevalence of left-sided hernias. Knowledge of the contents and boundaries of this enclosure can aid the physician in diagnosis. We explore the intraperitoneal and retroperitoneal diseases that present at the lumbocostal space, including lumbar hernias, which can be classified as congenital, acquired, traumatic, or iatrogenic in origin. In an evaluation, imaging is crucial for assessing musculofascial layer disruptions and hernia contents. Open and laparoscopic surgery, as well retromuscular lumbar hernia repair, are options to explore in surgical intervention, particularly if there are challenges in preliminary pain management. Keywords: Lumbar hernia, Costoiliac spaces, Petit's triangle, Grvnfeltt-lesshaft triangle, Lumbocostovertebral syndrome

  9. The Influence of Electrodes and Conditioning on Space Charge Accumulation in XLPE

    DEFF Research Database (Denmark)

    Fleming, R. J.; Henriksen, Mogens; Holbøll, Joachim

    2000-01-01

    . They also developed homocharge close to the electrodes. The choice of electrode material had little effect on the heterocharge profile in unconditioned samples. Conditioning by holding at 80°C for four days, at rotary pump pressure or at atmospheric pressure, suppressed the accumulation of heterocharge....... Homocharge accumulation close to the electrodes in samples with semicon electrodes was affected little by this conditioning, but was reduced considerably in samples with gold electrodes. Conditioning by holding at room temperature for seven days at rotary pump pressure had little effect. The heterocharge...

  10. HPS: A space fission power system suitable for near-term, low-cost lunar and planetary bases

    International Nuclear Information System (INIS)

    Houts, M.G.; Poston, D.I.; Ranken, W.A.

    1996-01-01

    Near-term, low-cost space fission power systems can enhance the feasibility and utility of lunar and planetary bases. One such system, the Heatpipe Power System (HPS), is described in this paper. The HPS draws on 40 yr of United States and international experience to enable a system that can be developed in <5 yr at a cost of <$100M. Total HPS mass is <600 kg at 5 kWe and <2000 kg at 50 kWe, assuming that thermoelectric power conversion is used. More advanced power conversion systems could reduce system mass significantly. System mass for planetary surface systems also may be reduced (1) if indigenous material is used for radiation shielding and (2) because of the positive effect of the gravitational field on heatpipe operation. The HPS is virtually non-radioactive at launch and is passively subcritical during all credible launch accidents. Full-system electrically heated testing is possible, and a ground nuclear power test is not needed for flight qualification. Fuel burnup limits are not reached for several decades, thus giving the system long-life potential

  11. Long-term biomass resources for energy aim - quantities, costs and conditions of the market

    International Nuclear Information System (INIS)

    Gylling, M.; Abildtrup, J.; Vodder Nielsen, K.; Petersen, S.M.; Varming, S.

    2001-01-01

    This project assesses the agricultural, technical and economic possibilities for producing the planned quantity of energy crops in year 2015. The assessments in this project are based on two essential assumptions: 1) The total demand for straw and energy crops to meet the energy plans is added up, and the available amount of straw is used first and energy crops will be used for the remaining amount. 2) As long as the present economic conditions for set-aside prevails, it will only be the set-aside areas that will be available for energy crop production. Energy crops are not seen as economic competitive with other cash-crops on the reform areas.Three different scenarios for the agricultural crop production up to year 2015 are outlined; a reference scenario where the current development is extrapolated; an environment scenario in which a higher degree of environmental awareness is taken into account and a market scenario in which the economic competitiveness of agricultural production gains more focus. (au)

  12. Low-Flow Liquid Desiccant Air-Conditioning: Demonstrated Performance and Cost Implications

    Energy Technology Data Exchange (ETDEWEB)

    Kozubal, E.; Herrmann, L.; Deru, M.; Clark, J.; Lowenstein, A.

    2014-09-01

    Cooling loads must be dramatically reduced when designing net-zero energy buildings or other highly efficient facilities. Advances in this area have focused primarily on reducing a building's sensible cooling loads by improving the envelope, integrating properly sized daylighting systems, adding exterior solar shading devices, and reducing internal heat gains. As sensible loads decrease, however, latent loads remain relatively constant, and thus become a greater fraction of the overall cooling requirement in highly efficient building designs, particularly in humid climates. This shift toward latent cooling is a challenge for heating, ventilation, and air-conditioning (HVAC) systems. Traditional systems typically dehumidify by first overcooling air below the dew-point temperature and then reheating it to an appropriate supply temperature, which requires an excessive amount of energy. Another dehumidification strategy incorporates solid desiccant rotors that remove water from air more efficiently; however, these systems are large and increase fan energy consumption due to the increased airside pressure drop of solid desiccant rotors. A third dehumidification strategy involves high flow liquid desiccant systems. These systems require a high maintenance separator to protect the air distribution system from corrosive desiccant droplet carryover and so are more commonly used in industrial applications and rarely in commercial buildings. Both solid desiccant systems and most high-flow liquid desiccant systems (if not internally cooled) add sensible energy which must later be removed to the air stream during dehumidification, through the release of sensible heat during the sorption process.

  13. Low-cost blast wave generator for studies of hearing loss and brain injury: blast wave effects in closed spaces.

    Science.gov (United States)

    Newman, Andrew J; Hayes, Sarah H; Rao, Abhiram S; Allman, Brian L; Manohar, Senthilvelan; Ding, Dalian; Stolzberg, Daniel; Lobarinas, Edward; Mollendorf, Joseph C; Salvi, Richard

    2015-03-15

    Military personnel and civilians living in areas of armed conflict have increased risk of exposure to blast overpressures that can cause significant hearing loss and/or brain injury. The equipment used to simulate comparable blast overpressures in animal models within laboratory settings is typically very large and prohibitively expensive. To overcome the fiscal and space limitations introduced by previously reported blast wave generators, we developed a compact, low-cost blast wave generator to investigate the effects of blast exposures on the auditory system and brain. The blast wave generator was constructed largely from off the shelf components, and reliably produced blasts with peak sound pressures of up to 198dB SPL (159.3kPa) that were qualitatively similar to those produced from muzzle blasts or explosions. Exposure of adult rats to 3 blasts of 188dB peak SPL (50.4kPa) resulted in significant loss of cochlear hair cells, reduced outer hair cell function and a decrease in neurogenesis in the hippocampus. Existing blast wave generators are typically large, expensive, and are not commercially available. The blast wave generator reported here provides a low-cost method of generating blast waves in a typical laboratory setting. This compact blast wave generator provides scientists with a low cost device for investigating the biological mechanisms involved in blast wave injury to the rodent cochlea and brain that may model many of the damaging effects sustained by military personnel and civilians exposed to intense blasts. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Experimental study of performance of a dry cooling and dedicated ventilation (DCDV) system under different space cooling load conditions

    International Nuclear Information System (INIS)

    Jia, Jie; Lee, W.L.; Chen, Hua

    2013-01-01

    Highlights: • This is an experimental study of the use of DCDV system for achieving the decoupling and energy saving objectives. • The study focuses on side-by-side comparison of the DCDV and conventional systems. • DCDV system can better achieve the desired space air conditions and is more energy efficient. • A prediction model has been developed to relate the possible condensation period with different operating parameters. • The results are useful for wider application of DCDV system. - Abstract: The use of DCDV system for decoupling dehumidification from cooling to achieve energy saving objective for air-conditioning of office environments in Hong Kong was confirmed effective based on simulation studies by the authors. However, given that simulation typically assumes a perfect control and feedback system, whether or not the benefits of DCDV system can be realized in practice, in particular under various space part load ratio (PLR) and sensible heat ratio (SHR) conditions, is subject to experimental verifications. In this study, a prototype which could be switched between the proposed DCDV system mode and the conventional system mode was constructed in a test facility for laboratory experiments. Through two sets of identical experiments under various space cooling load conditions, it was found that if compared to the conventional system, DCDV system could perform slightly better in achieving the desired indoor condition and in reducing the moisture-related air quality problems, but would result in 1–3% higher in cooling output. As for the overall coefficient of performance (COP o ), the DCDV system was found performed better by 5.6–7.2%. Additional experimental analysis was conducted for the development of a prediction model to relate the possible condensation period (ψ) on the DC coil with different operating parameters

  15. Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions.

    Science.gov (United States)

    Tan, Tiong Yang; Dillon, Oliver James; Stark, Zornitza; Schofield, Deborah; Alam, Khurshid; Shrestha, Rupendra; Chong, Belinda; Phelan, Dean; Brett, Gemma R; Creed, Emma; Jarmolowicz, Anna; Yap, Patrick; Walsh, Maie; Downie, Lilian; Amor, David J; Savarirayan, Ravi; McGillivray, George; Yeung, Alison; Peters, Heidi; Robertson, Susan J; Robinson, Aaron J; Macciocca, Ivan; Sadedin, Simon; Bell, Katrina; Oshlack, Alicia; Georgeson, Peter; Thorne, Natalie; Gaff, Clara; White, Susan M

    2017-09-01

    additional diagnosis (95% CI, A$4304-A$15 404 [US$3263-US$11 678]) compared with the standard diagnostic pathway. Even if WES were performed at the first genetics appointment, there would be an incremental cost savings of A$5461 (US$4140) (95% CI, A$1433-A$10 557 [US$1086- US$8004]) per additional diagnosis compared with the standard diagnostic pathway. Singleton WES in children with suspected monogenic conditions has high diagnostic yield, and cost-effectiveness is maximized by early application in the diagnostic pathway. Pediatricians should consider early referral of children with undiagnosed syndromes to clinical geneticists.

  16. Modeling of Fog and Smoke Attenuation in Free Space Optical Communications Link Under Controlled Laboratory Conditions

    Czech Academy of Sciences Publication Activity Database

    Ijaz, M.; Ghassemlooy, Z.; Pešek, J.; Fišer, Ondřej; Le Minh, H.; Bentley, E.

    2013-01-01

    Roč. 31, č. 11 (2013), s. 1720-1726 ISSN 0733-8724 R&D Projects: GA ČR(CZ) GAP102/11/1376 Institutional support: RVO:68378289 Keywords : Fog attenuation * free space optics * smoke attenuation * visibility Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 2.862, year: 2013 http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=6497447&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D6497447

  17. Does the air condition system in busses spread allergic fungi into driver space?

    Science.gov (United States)

    Sowiak, Małgorzata; Kozajda, Anna; Jeżak, Karolina; Szadkowska-Stańczyk, Irena

    2018-02-01

    The aim of this study was to establish whether the air-conditioning system in buses constitutes an additional source of indoor air contamination with fungi, and whether or not the fungi concentration depends on the period from the last disinfection of the system, combined with replacement of the cabin dust particle filter. The air samples to fungi analysis using impact method were taken in 30 buses (20 with an air-conditioning system, ACS; 10 with a ventilation system, VS) in two series: 1 and 22 weeks after cabin filter replacement and disinfection of the air-conditioning system. During one test in each bus were taken two samples: before the air-conditioning or ventilation system switched on and 6 min after operating of these systems. The atmospheric air was the external background (EB). After 1 week of use of the system, the fungi concentrations before starting of the ACS and VS system were 527.8 and 1053.0 cfu/m 3 , respectively, and after 22 weeks the concentrations were 351.9 and 1069.6 cfu/m 3 , respectively. While in the sample after 6 min of ACS and VS system operating, the fungi concentration after 1 week of use was 127.6 and 233.7 cfu/m 3 , respectively, and after 22 weeks it was 113.3 and 324.9 cfu/m 3 , respectively. Results do not provide strong evidence that air-conditioning system is an additional source of indoor air contamination with fungi. A longer operation of the system promoted increase of fungi concentration in air-conditioned buses only.

  18. Corrections to air kerma rate measurements of 125I brachytherapy sources to free space conditions

    International Nuclear Information System (INIS)

    Shipley, D.R.; Duane, S.

    1994-05-01

    Air kerma rate measurements have been made between 40 cm and 100 cm from one of a set of 125 I reference sources within the facilities of Amersham International plc. Monte Carlo techniques have been used to calculate the air kerma rate components over the same range of distances from this source. After comparing the calculated data with measurements, the compliance of the data with the inverse square law was investigated, and corrections were derived to obtain the air kerma rate at 1 m in free space from each source. Simulations of the experimental setup with an isotropic monoenergetic point source close to the effective energy of 125 I were found to reproduce the air kerma rate measurements reasonably accurately, and indicated that the contribution due to scattered photons was significant. The overall correction (which is defined as the product of individual corrections for chamber size effect, air attenuation and radiation scatter) required to the inverse square law to obtain the air kerma rate at 1 m in free space was found to be 0.981, 0.984 and 0.980, respectively, for air kerma rate measurements at 40 cm, 60 cm and 100 cm from the 125 I reference source. The total uncertainty in these corrections was estimated to be 0.88% at the 1σ level. (author)

  19. Nonlinear dynamic analysis and state space representation of a manipulator under viscoelastic material conditions

    Directory of Open Access Journals (Sweden)

    Esfandiar, H.

    2013-05-01

    Full Text Available In this paper, based on the VoigtKelvin constitutive model, nonlinear dynamic modelling and state space representation of a viscoelastic beam acting as a flexible robotic manipulator is investigated. Complete nonlinear dynamic modelling of a viscoelastic beam without premature linearisation of dynamic equations is developed. The adopted method is capable of reproducing nonlinear dynamic effects, such as beam stiffening due to centrifugal and Coriolis forces induced by rotation of the joints. Structural damping effects on the models dynamic behaviour are also shown. A reliable model for a viscoelastic beam is subsequently presented. The governing equations of motion are derived using Hamiltons principle, and using the finite difference method, nonlinear partial differential equations are reduced to ordinary differential equations. For the purpose of flexible manipulator control, the standard form of state space equations for the viscoelastic link and the actuator is obtained. Simulation results indicate substantial improvements in dynamic behaviour, and a parameter sensitivity study is carried out to investigate the effect of structural damping on the vibration amplitude.

  20. Assuming it is all about conditions : Framing a simulation model for complex, adaptive urban space

    NARCIS (Netherlands)

    Yamu, Claudia; de Roo, Gert; Frankhauser, Pierre

    2016-01-01

    In this paper, we explore the route beyond the conventional, linear attitude within planning and its rationality debate. We combine our theoretical reasoning with a multiscale approach and with fractal-like argumentation which results in a frame of conditions which is supported by the outline of a

  1. Analysis of optical properties behaviour of CLEARCERAM, fused silica and CaF2 glasses exposed to simulated space conditions

    Science.gov (United States)

    Fernández-Rodríguez, M.; Alvarado, C. G.; Núñez, A.; Álvarez-Herrero, A.

    2017-11-01

    Optical instrumentation on-board satellites suffer degradation due to the hostile conditions of space environment. Space conditions produce instrumentation performances changes causing a decrease or a cancellation of their features. Particularly, space environment conditions have a significant influence on the optical properties of glasses which are part of space optical systems. Space environment characteristics which effects on the optical system have to be taken into account are: outgassing, volatile components, gas or water vapor which form part of the spacecraft materials, vacuum, microgravity, micrometeorites, space debris, thermal, mechanical and radiation environment and effects of the high atmosphere [1]. This work is focused on analyzing temperature variations and ultraviolet (UV) and gamma radiation effects on the optical properties of several glasses used on space applications. Thermal environment is composed of radiation from the Sun, the albedo and the Earth radiation and the radiation from the spacecraft to deep space. Flux and influence of temperature on satellite materials depend on factors as the period of year or the position of them on the space system. Taking into account that the transfer mechanisms of heat are limited by the conduction and the radiation, high gradients of temperature are obtained in system elements which can cause changes of their optical properties, birefringence… Also, these thermal cycles can introduce mechanical loads into material structure due to the expansion and the contraction of the material leading to mechanical performances degradation [2]. However, it is the radiation environment the main cause of damage on optical properties of materials used on space instrumentation. This environment consists of a wide range of energetic particles between keV and MeV which are trapped by the geomagnetic field or are flux of particles that cross the Earth environment from the external of the Solar System [3]. The damage

  2. Provider costs for prevention and treatment of cardiovascular and related conditions in low- and middle-income countries: a systematic review.

    Science.gov (United States)

    Brouwer, Elizabeth D; Watkins, David; Olson, Zachary; Goett, Jane; Nugent, Rachel; Levin, Carol

    2015-11-26

    The burden of cardiovascular disease (CVD) and CVD risk conditions is rapidly increasing in low- and middle-income countries, where health systems are generally ill-equipped to manage chronic disease. Policy makers need an understanding of the magnitude and drivers of the costs of cardiovascular disease related conditions to make decisions on how to allocate limited health resources. We undertook a systematic review of the published literature on provider-incurred costs of treatment for cardiovascular diseases and risk conditions in low- and middle-income countries. Total costs of treatment were inflated to 2012 US dollars for comparability across geographic settings and time periods. This systematic review identified 60 articles and 143 unit costs for the following conditions: ischemic heart disease, non-ischemic heart diseases, stroke, heart failure, hypertension, diabetes, and chronic kidney disease. Cost data were most readily available in middle-income countries, especially China, India, Brazil, and South Africa. The most common conditions with cost studies were acute ischemic heart disease, type 2 diabetes mellitus, stroke, and hypertension. Emerging economies are currently providing a base of cost evidence for NCD treatment that may prove useful to policy-makers in low-income countries. Initial steps to publicly finance disease interventions should take account of costs. The gaps and limitations in the current literature include a lack of standardized reporting as well as sparse evidence from low-income countries.

  3. Gym-based exercise was more costly compared with home-based exercise with telephone support when used as maintenance programs for adults with chronic health conditions: cost-effectiveness analysis of a randomised trial

    Directory of Open Access Journals (Sweden)

    Paul Jansons

    2018-01-01

    Registration: ACTRN12610001035011. [Jansons P, Robins L, O’Brien L, Haines T (2018 Gym-based exercise was more costly compared with home-based exercise with telephone support when used as maintenance programs for adults with chronic health conditions: cost-effectiveness analysis of a randomised trial. Journal of Physiotherapy 64: 48–54

  4. Investigating the Effects of Simulated Space conditions on Novel Extremely Halophilic Archaea: Halovarius Luteus gen. nov., sp. nov.

    Science.gov (United States)

    Feshangsaz, Niloofar; Van Loon, ing.. Jack J. W. A.; Nazmi, Kamran; Semsarha, Farid

    2016-07-01

    Studying halophiles from different environments of Earth provide new insights into our search for life in the universe. Haloarchaea show some unique characteristics and physiological adaptations like acidic proteins against harsh environments such as natural brine with salt concentration approaching saturation (5 M) and regions with low active water. These properties make haloarchaea interesting candidate for astrobiological studies. Halovarius luteus gen. nov., sp. nov. a novel extremely halophilic archaeon from Urmia salt lake, in Iran has been chosen to explore its resistance against a series of extreme conditions. The aim of this study is to assess the resistance of strain DA50T under the effects of simulated space conditions like simulated microgravity, hypergravity, and desiccation. In this paper we will discuss the results of these studies where we specifically focus on changes in carotenoid pigments production and whole cell proteome. This is the first report of very novel Iranian archaea in response to extreme space conditions. The pigments were extracted by acetone and methanol. Pigments were analyzed by scanning the absorbance spectrum in the UV-VIS spectrophotometer. And they were separated by TLC. Whole protein from cell lysate supernatant was extracted after lysis with Bacterial Protein Extraction Reagent and fractionated by RP-HPLC using C18 column. Proteome analyzed by electrophoresis (SDS-PAGE), and MALDI-TOF. Carotenoid pigments are formed under different extreme conditions such as dry environment and gravitational changes. Also the protein composition exhibits alterations after exposure to the same conditions. Our conclusion is that pigments and proteins formation depend on the growth circumstances. Halophiles use this as an adaptation to survive under different environmental conditions.

  5. Early development conditions and the oxidative cost of social context in adulthood: an experimental study in birds

    Directory of Open Access Journals (Sweden)

    Ana eRomero-Haro

    2015-04-01

    Full Text Available Environmental conditions during early life may shape phenotype in adulthood. Early adverse conditions may increase the oxidative stress in adults, which could affect their reproductive output and survival. It has also been hypothesized that the larger the reproductive investment, the higher the oxidative stress. We tested this and the potential influence of early oxidative stress on how individuals respond to a reproductive stimulation. The synthesis of the antioxidant glutathione was inhibited in captive zebra finches (Taeniopygia guttata during growth. In adulthood, the expression of a carotenoid-based sexual signal, bill redness, increased in both sexes, with females also being heavier than controls. The social context of control and glutathione-inhibited males was then manipulated to stimulate precopulatory reproductive investments. Males were individually caged in front of a female or another male. We predicted that males enduring lower early antioxidant levels and placed close to a female should pay the highest cost of a hypothetical increase in bill redness in terms of oxidative damage. However, early conditions only influenced the male’s phenotype via their partners. Males caged with females showed increases in circulating pigment (carotenoid levels, but only when females endured early low antioxidant values. This was probably related to the higher attractiveness of these females. Nevertheless, the bill redness of males did not differ during the social manipulation. Moreover, males facing females from any early condition group showed lower oxidative damage levels in plasma lipids. This result agrees with some findings in rodents, also in captivity. However, the effect may be due to increased triglyceride levels and body mass in males not facing females, as variation in these traits explained oxidative damage variability. The importance of considering housing conditions and life history when interpreting oxidative stress-related trade

  6. Ultrastructure of chlorella pyrenoidosa (Strain g-11-1) cell grown for a long time under conditions of space flight

    International Nuclear Information System (INIS)

    Sitnik, K.M.; Kordyum, Ye.L.; Mashins'kij, O.L.; Popova, A.F.; Grechko, G.M.

    1979-01-01

    Presented are the data on the electron-microscopic analysis of the Chlorella pyrenoidosa culture (the D-11-1 strain, a pigmentary mutant) growing in the IFS-2 instruments (an organic nutrient medium, darkness) during 28 days on board the space laboratory ''Salyut-6''. The cell density in the experimental culture is 4.6 times greater than the one under control. A number of differences in the structural-functional organization of experimental and control cells is shown. The investigations performed have shown that the cosmic flight factors significantly affect the growth and vital activity of the Chlorella culture having been in a physiologically active state for a long time under conditions of space flight

  7. Halophilic archaea on Earth and in space: growth and survival under extreme conditions.

    Science.gov (United States)

    Oren, Aharon

    2014-12-13

    Salts are abundant on Mars, and any liquid water that is present or may have been present on the planet is expected to be hypersaline. Halophilic archaea (family Halobacteriaceae) are the microorganisms best adapted to life at extremes of salinity on Earth. This paper reviews the properties of the Halobacteriaceae that may make the group good candidates for life also on Mars. Many species resist high UV and gamma radiation levels; one species has survived exposure to vacuum and radiation during a space flight; and there is at least one psychrotolerant species. Halophilic archaea may survive for millions of years within brine inclusions in salt crystals. Many species have different modes of anaerobic metabolism, and some can use light as an energy source using the light-driven proton pump bacteriorhodopsin. They are also highly tolerant to perchlorate, recently shown to be present in Martian soils, and some species can even use perchlorate as an electron acceptor to support anaerobic growth. The presence of characteristic carotenoid pigments (α-bacterioruberin and derivatives) makes the Halobacteriaceae easy to identify by Raman spectroscopy. Thus, if present on Mars, such organisms may be detected by Raman instrumentation planned to explore Mars during the upcoming ExoMars mission. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  8. Investigation of optimum conditions and costs estimation for degradation of phenol by solar photo-Fenton process

    Science.gov (United States)

    Gar Alalm, Mohamed; Tawfik, Ahmed; Ookawara, Shinichi

    2017-03-01

    In this study, solar photo-Fenton reaction using compound parabolic collectors reactor was assessed for removal of phenol from aqueous solution. The effect of irradiation time, initial concentration, initial pH, and dosage of Fenton reagent were investigated. H2O2 and aromatic intermediates (catechol, benzoquinone, and hydroquinone) were quantified during the reaction to study the pathways of the oxidation process. Complete degradation of phenol was achieved after 45 min of irradiation when the initial concentration was 100 mg/L. However, increasing the initial concentration up to 500 mg/L inhibited the degradation efficiency. The dosage of H2O2 and Fe+2 significantly affected the degradation efficiency of phenol. The observed optimum pH for the reaction was 3.1. Phenol degradation at different concentration was fitted to the pseudo-first order kinetic according to Langmuir-Hinshelwood model. Costs estimation for a large scale reactor based was performed. The total costs of the best economic condition with maximum degradation of phenol are 2.54 €/m3.

  9. Development of an environmental chamber for evaluating the performance of low-cost air quality sensors under controlled conditions

    Science.gov (United States)

    Papapostolou, Vasileios; Zhang, Hang; Feenstra, Brandon J.; Polidori, Andrea

    2017-12-01

    A state-of-the-art integrated chamber system has been developed for evaluating the performance of low-cost air quality sensors. The system contains two professional grade chamber enclosures. A 1.3 m3 stainless-steel outer chamber and a 0.11 m3 Teflon-coated stainless-steel inner chamber are used to create controlled aerosol and gaseous atmospheres, respectively. Both chambers are temperature and relative humidity controlled with capability to generate a wide range of environmental conditions. The system is equipped with an integrated zero-air system, an ozone and two aerosol generation systems, a dynamic dilution calibrator, certified gas cylinders, an array of Federal Reference Method (FRM), Federal Equivalent Method (FEM), and Best Available Technology (BAT) reference instruments and an automated control and sequencing software. Our experiments have demonstrated that the chamber system is capable of generating stable and reproducible aerosol and gas concentrations at low, medium, and high levels. This paper discusses the development of the chamber system along with the methods used to quantitatively evaluate sensor performance. Considering that a significant number of academic and research institutions, government agencies, public and private institutions, and individuals are becoming interested in developing and using low-cost air quality sensors, it is important to standardize the procedures used to evaluate their performance. The information discussed herein provides a roadmap for entities who are interested in characterizing air quality sensors in a rigorous, systematic and reproducible manner.

  10. The Design and Operation of Suborbital Low Cost and Low Risk Vehicle to the Edge of Space (SOLVES)

    Science.gov (United States)

    Ridzuan Zakaria, Norul; Nasrun, Nasri; Rashidy Zulkifi, Mohd; Izmir Yamin, Mohd; Othman, Jamaludin; Rafidi Zakaria, Norul

    2013-09-01

    Inclusive in the planning of Spaceport Malaysia are 2 local suborbital vehicles development. One of the vehicles is called SOLVES or Suborbital Low Cost and Low Risk Vehicle to the Edge of Space. The emphasis on the design and operation of SOLVES is green and robotic technology, where both green technology and robotic technology are used to protect the environment and enhance safety. As SOLVES climbs, its center of gravity stabilizes and remains at the bottom as its propellant being used until it depletes, due to the position of the vehicle's passenger cabin and its engines at its lower end. It will reach 80km from sea level generally known as "the edge of space" due to its momentum although its propellant will be depleted at a lower altitude. As the suborbital vehicle descends tail first, its wings automatically extend and rotate at horizontal axes perpendicular to the fuselage. These naturally and passively rotating wings ensure controlled low velocity and stable descend of the vehicle. The passenger cabin also rotates automatically at a steady low speed at the centerline of its fuselage as it descends, caused naturally by the lift force, enabling its passengers a surrounding 360 degrees view. SOLVES is steered automatically to its landing point by an electrical propulsion system with a vectoring nozzle. The electrical propulsion minimizes space and weight and is free of pollution and noise. Its electrical power comes from a battery aided by power generated by the naturally rotating wings. When the vehicle lands, it is in the safest mode as its propellant is depleted and its center of gravity remains at the bottom of its cabin. The cabin, being located at the bottom of the fuselage, enables very convenient, rapid and safe entry and exit of its passengers. SOLVES will be a robotic suborbital vehicle with green technology. The vehicle will carry 4 passengers and each passenger will be trained to land the vehicle manually if the fully automated landing system fails

  11. Electro activation of persulfate using iron sheet as low-cost electrode: the role of the operating conditions.

    Science.gov (United States)

    Silveira, Jefferson E; Cardoso, Tais O; Barreto-Rodrigues, Marcio; Zazo, Juan A; Casas, José A

    2018-05-01

    This work assesses the role of the operational conditions upon the electro-activation of persulfate (PS) using sacrificed iron electrode as a continuous low-cost Fe 2+ source. An aqueous phenol solution (100 mg L -1 ) was selected as model effluent. The studied variables include current density (1-10 mA cm -2 ), persulfate concentration (0.7-2.85 g L -1 ), temperature (30-90°C) and the solution conductivity (2.7-20.7 mS cm -1 ) using Na 2 SO 4 and NaCl as supporting electrolyte. A mineralization degree of around 80% with Na 2 SO 4 and 92% in presence of NaCl was achieved at 30°C using 2.15 g L -1 PS at the lowest current density tested (1 mA cm -2 ). Besides PS concentration, temperature was the main variable affecting the process. In the range of 30-70°C, it showed a positive effect, achieving TOC conversion above 95% (using Na 2 SO 4 under the previous conditions) along with a significant increase in iron sludge, which adversely affects the economy of the process. A lumped and simplified kinetic model based on persulfate consumption and TOC mineralization is suggested. The activation energy obtained for the TOC decay was 29 kJ mol -1 . An estimated operating cost of US$ 3.00 per m 3 was obtained, demonstrating the economic feasibility of this process.

  12. Crew-MC communication and characteristics of crewmembers' sleep under conditions of simulated prolonged space flight

    Science.gov (United States)

    Shved, Dmitry; Gushin, Vadim; Yusupova, Anna; Ehmann, Bea; Balazs, Laszlo; Zavalko, Irina

    Characteristics of crew-MC communication and psychophysiological state of the crewmembers were studied in simulation experiment with 520-day isolation. We used method of computerized quantitative content analysis to investigate psychologically relevant characteristics of the crew’s messages content. Content analysis is a systematic, reproducible method of reducing of a text array to a limited number of categories by means of preset scientifically substantiated rules of coding (Berelson, 1971, Krippendorff, 2004). All statements in the crew’s messages to MC were coded with certain psychologically relevant content analysis categories (e.g. ‘Needs’, ‘Negativism’, ‘Time’). We attributed to the ‘Needs’ category statements (semantic units), containing the words, related to subject’s needs and their satisfaction, e.g. ‘‘necessary, need, wish, want, demand’’. To the ‘Negativism’ category we refer critical statements, containing such words as ‘‘mistakes, faults, deficit, shortage’’. The ‘Time’ category embodies statements related to time perception, e.g. “hour, day, always, never, constantly”. Sleep study was conducted with use of EEG and actigraphy techniques to assess characteristics of the crewmembers’ night sleep, reflecting the crew’s adaptation to the experimental conditions. The overall amount of communication (quantity of messages and their length) positively correlated with sleep effectiveness (time of sleep related to time in bed) and with delta sleep latency. Occurrences of semantic units in categories ‘Time’ and ‘Negativism’ negatively correlated with sleep latency, and positively - with delta sleep latency and sleep effectiveness. Frequency of time-related semantic units’ utilization in the crew’s messages was significantly increasing during or before the key events of the experiment (beginning of high autonomy, planetary landing simulation, etc.). It is known that subjective importance of time

  13. Necessary and Sufficient Conditions for Boundedness of Commutators of the General Fractional Integral Operators on Weighted Morrey Spaces

    Directory of Open Access Journals (Sweden)

    Zengyan Si

    2012-01-01

    Full Text Available We prove that b is in Lipβ(ω if and only if the commutator [b,L-α/2] of the multiplication operator by b and the general fractional integral operator L-α/2 is bounded from the weighted Morrey space Lp,k(ω to Lq,kq/p(ω1-(1-α/nq,ω, where 0(1-k/(p/(q-k, and here rω denotes the critical index of ω for the reverse Hölder condition.

  14. Salmonellosis Hospitalizations in the United States: Associated Chronic Conditions, Costs, and Hospital Outcomes, 2011, Trends 2000-2011.

    Science.gov (United States)

    Cummings, Patricia L; Kuo, Tony; Javanbakht, Marjan; Shafir, Shira; Wang, May; Sorvillo, Frank

    2016-01-01

    Hospitalized salmonellosis patients with concurrent chronic conditions may be at increased risk for adverse outcomes, increasing the costs associated with hospitalization. Identifying important modifiable risk factors for this predominantly foodborne illness may assist hospitals, physicians, and public health authorities to improve management of these patients. The objectives of this study were to (1) quantify the burden of salmonellosis hospitalizations in the United States, (2) describe hospitalization characteristics among salmonellosis patients with concurrent chronic conditions, and (3) examine the relationships between salmonellosis and comorbidities by four hospital-related outcomes. A retrospective analysis of salmonellosis discharges was conducted using the Agency for Healthcare Research and Quality's Nationwide Inpatient Sample for 2011. A supplemental trend analysis was performed for the period 2000-2011. Hospitalization characteristics were examined using multivariable regression modeling, with a focus on four outcome measures: in-hospital death, total amount billed by hospitals for services, length of stay, and disease severity. In 2011, there were 11,032 total salmonellosis diagnoses; 7496 were listed as the primary diagnosis, with 86 deaths (case-fatality rate = 1.2%). Multivariable regression analyses revealed a greater number of chronic conditions (≥4) among salmonellosis patients was associated with higher mean total amount billed by hospitals for services, longer length of stay, and greater disease severity (p ≤ 0.05). From 2000 to 2011, hospital discharges for salmonellosis increased by 27.2%, and the mean total amount billed by hospitals increased nearly threefold: $9,777 (2000) to $29,690 (2011). Observed increases in hospitalizations indicate the burden of salmonellosis remains substantial in the United States. The positive association between increased number of chronic conditions and the four hospital-related outcomes affirms

  15. Motivation for a near term gun launch to space demonstration and a variable induction power supply concept to minimize initial demonstration costs

    International Nuclear Information System (INIS)

    Palmer, M.R.

    1993-01-01

    The history of the Gun Launch to Space (GLTS) concept is briefly reviewed along with recent progress and motivations for a near term launch demonstration. A current multiplying reconfigurable inductor design is developed which could couple to an existing battery system to power a GLTS railgun demonstration at the 300 megajoule muzzle energy level. The design is developed using proven approaches and performance levels and appears capable of reducing the power supply cost for an initial GLTS demonstration below that of a simple battery charged inductor system. Possible uses are (1) launching of space weapons; (2) launching of communication satellites; (3) and launching of satellites for space disposal of radioactive wastes

  16. Modelling of 10 Gbps Free Space Optics Communication Link Using Array of Receivers in Moderate and Harsh Weather Conditions

    Science.gov (United States)

    Gupta, Amit; Shaina, Nagpal

    2017-08-01

    Intersymbol interference and attenuation of signal are two major parameters affecting the quality of transmission in Free Space Optical (FSO) Communication link. In this paper, the impact of these parameters on FSO communication link is analysed for delivering high-quality data transmission. The performance of the link is investigated under the influence of amplifier in the link. The performance parameters of the link like minimum bit error rate, received signal power and Quality factor are examined by employing erbium-doped fibre amplifier in the link. The effects of amplifier are visualized with the amount of received power. Further, the link is simulated for moderate weather conditions at various attenuation levels on transmitted signal. Finally, the designed link is analysed in adverse weather conditions by using high-power laser source for optimum performance.

  17. Simulation of the impact of financial incentives on solar energy utilization for space conditioning and water heating: 1985

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, H C

    1979-01-01

    Financial incentives designed to accelerate the use of solar energy for heating, cooling, and water heating of buildings have been proposed by both state and federal legislative bodies in the U.S.A. Among the most frequently mentioned incentives are sales and property tax exemptions, tax deductions and credits, rapid amortization provisions, and interest rate subsidies. At the present time there is little available information regarding the ability of such incentives to advance the rate of solar energy utilization. This paper describes the derivation and use of a computer simulation model designed to estimate solar energy use for space conditioning and water heating for given economic, climatic, and technological conditions. When applied to data from the Denver, Colorado metropolitan area, the simulation model predicts that sales tax exemptions would have little impact over the next decade, interest rate subsidies could more than double solar energy use, and the other proposed incentives would have an intermediate impact.

  18. Spectrophotometric analysis of tomato plants produced from seeds exposed under space flight conditions for a long time

    Science.gov (United States)

    Nechitailo, Galina S.; Yurov, S.; Cojocaru, A.; Revin, A.

    The analysis of the lycopene and other carotenoids in tomatoes produced from seeds exposed under space flight conditions at the orbital station MIR for six years is presented in this work. Our previous experiments with tomato plants showed the germination of seeds to be 32%Genetic investigations revealed 18%in the experiment and 8%experiments were conducted to study the capacity of various stimulating factors to increase germination of seeds exposed for a long time to the action of space flight factors. An increase of 20%achieved but at the same time mutants having no analogues in the control variants were detected. For the present investigations of the third generation of plants produced from seeds stored for a long time under space flight conditions 80 tomatoes from forty plants were selected. The concentration of lycopene in the experimental specimens was 2.5-3 times higher than in the control variants. The spectrophotometric analysis of ripe tomatoes revealed typical three-peaked carotenoid spectra with a high maximum of lycopene (a medium maximum at 474 nm), a moderate maximum of its predecessor, phytoin, (a medium maximum at 267 nm) and a low maximum of carotenes. In green tomatoes, on the contrary, a high maximum of phytoin, a moderate maximum of lycopene and a low maximum of carotenes were observed. The results of the spectral analysis point to the retardation of biosynthesis of carotenes while the production of lycopene is increased and to the synthesis of lycopene from phytoin. Electric conduction of tomato juice in the experimental samples is increased thus suggesting higher amounts of carotenoids, including lycopene and electrolytes. The higher is the value of electric conduction of a specimen, the higher are the spectral maxima of lycopene. The hydrogen ion exponent of the juice of ripe tomatoes increases due to which the efficiency of ATP biosynthesis in cell mitochondria is likely to increase, too. The results demonstrating an increase in the content

  19. Conditional Stochastic Models in Reduced Space: Towards Efficient Simulation of Tropical Cyclone Precipitation Patterns

    Science.gov (United States)

    Dodov, B.

    2017-12-01

    Stochastic simulation of realistic and statistically robust patterns of Tropical Cyclone (TC) induced precipitation is a challenging task. It is even more challenging in a catastrophe modeling context, where tens of thousands of typhoon seasons need to be simulated in order to provide a complete view of flood risk. Ultimately, one could run a coupled global climate model and regional Numerical Weather Prediction (NWP) model, but this approach is not feasible in the catastrophe modeling context and, most importantly, may not provide TC track patterns consistent with observations. Rather, we propose to leverage NWP output for the observed TC precipitation patterns (in terms of downscaled reanalysis 1979-2015) collected on a Lagrangian frame along the historical TC tracks and reduced to the leading spatial principal components of the data. The reduced data from all TCs is then grouped according to timing, storm evolution stage (developing, mature, dissipating, ETC transitioning) and central pressure and used to build a dictionary of stationary (within a group) and non-stationary (for transitions between groups) covariance models. Provided that the stochastic storm tracks with all the parameters describing the TC evolution are already simulated, a sequence of conditional samples from the covariance models chosen according to the TC characteristics at a given moment in time are concatenated, producing a continuous non-stationary precipitation pattern in a Lagrangian framework. The simulated precipitation for each event is finally distributed along the stochastic TC track and blended with a non-TC background precipitation using a data assimilation technique. The proposed framework provides means of efficient simulation (10000 seasons simulated in a couple of days) and robust typhoon precipitation patterns consistent with observed regional climate and visually undistinguishable from high resolution NWP output. The framework is used to simulate a catalog of 10000 typhoon

  20. Life-cycle cost as basis to optimize waste collection in space and time: A methodology for obtaining a detailed cost breakdown structure.

    Science.gov (United States)

    Sousa, Vitor; Dias-Ferreira, Celia; Vaz, João M; Meireles, Inês

    2018-05-01

    Extensive research has been carried out on waste collection costs mainly to differentiate costs of distinct waste streams and spatial optimization of waste collection services (e.g. routes, number, and location of waste facilities). However, waste collection managers also face the challenge of optimizing assets in time, for instance deciding when to replace and how to maintain, or which technological solution to adopt. These issues require a more detailed knowledge about the waste collection services' cost breakdown structure. The present research adjusts the methodology for buildings' life-cycle cost (LCC) analysis, detailed in the ISO 15686-5:2008, to the waste collection assets. The proposed methodology is then applied to the waste collection assets owned and operated by a real municipality in Portugal (Cascais Ambiente - EMAC). The goal is to highlight the potential of the LCC tool in providing a baseline for time optimization of the waste collection service and assets, namely assisting on decisions regarding equipment operation and replacement.

  1. Cost-effectiveness of remote ischaemic conditioning as an adjunct to primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction

    DEFF Research Database (Denmark)

    Sloth, Astrid D; Schmidt, Michael R; Munk, Kim

    2016-01-01

    AIMS: Remote ischaemic conditioning seems to improve long-term clinical outcomes in patients undergoing primary percutaneous coronary intervention. Remote ischaemic conditioning can be applied with cycles of alternating inflation and deflation of a blood-pressure cuff. We evaluated the cost...

  2. Online sequential condition prediction method of natural circulation systems based on EOS-ELM and phase space reconstruction

    International Nuclear Information System (INIS)

    Chen, Hanying; Gao, Puzhen; Tan, Sichao; Tang, Jiguo; Yuan, Hongsheng

    2017-01-01

    Highlights: •An online condition prediction method for natural circulation systems in NPP was proposed based on EOS-ELM. •The proposed online prediction method was validated using experimental data. •The training speed of the proposed method is significantly fast. •The proposed method can achieve good accuracy in wide parameter range. -- Abstract: Natural circulation design is widely used in the passive safety systems of advanced nuclear power reactors. The irregular and chaotic flow oscillations are often observed in boiling natural circulation systems so it is difficult for operators to monitor and predict the condition of these systems. An online condition forecasting method for natural circulation system is proposed in this study as an assisting technique for plant operators. The proposed prediction approach was developed based on Ensemble of Online Sequential Extreme Learning Machine (EOS-ELM) and phase space reconstruction. Online Sequential Extreme Learning Machine (OS-ELM) is an online sequential learning neural network algorithm and EOS-ELM is the ensemble method of it. The proposed condition prediction method can be initiated by a small chunk of monitoring data and it can be updated by newly arrived data at very fast speed during the online prediction. Simulation experiments were conducted on the data of two natural circulation loops to validate the performance of the proposed method. The simulation results show that the proposed predication model can successfully recognize different types of flow oscillations and accurately forecast the trend of monitored plant variables. The influence of the number of hidden nodes and neural network inputs on prediction performance was studied and the proposed model can achieve good accuracy in a wide parameter range. Moreover, the comparison results show that the proposed condition prediction method has much faster online learning speed and better prediction accuracy than conventional neural network model.

  3. Wave fields in Weyl spaces and conditions for the existence of a preferred pseudo-Riemannian structure

    International Nuclear Information System (INIS)

    Audretsch, J.; Gaehler, F.; Straumann, N.

    1984-01-01

    Previous axiomatic approaches to general relativity which led to a Weylian structure of space-time are supplemented by a physical condition which implies the existence of a preferred pseudo-Riemannian structure. It is stipulated that the trajectories of the short wave limit of classical massive fields agree with the geodesics of the Weyl connection and it is shown that this is equivalent to the vanishing of the covariant derivative of a ''mass function'' of nontrivial Weyl type.This in turn is proven to be equivalent to the existence of a preferred metric of the conformal structure such that the Weyl connection is reducible to a connection of the bundle of orthonormal frames belonging to this distinguished metric. (orig.)

  4. Trade study for water and waste management concepts. Task 7: Support special analysis. [cost analysis of life support systems for waste utilization during space missions

    Science.gov (United States)

    1975-01-01

    Cost analyses and tradeoff studies are given for waste management in the Space Station, Lunar Surface Bases, and interplanetary space missions. Crew drinking water requirements are discussed and various systems to recycle water are examined. The systems were evaluated for efficiency and weight savings. The systems considered effective for urine water recovery were vapor compression, flash evaporation, and air evaporation with electrolytic pretreatment. For wash water recovery, the system of multifiltration was selected. A wet oxidation system, which can process many kinds of wastes, is also considered.

  5. Low cost monitoring from space using Landsat TM time series and open source technologies: the case study of Iguazu park

    Science.gov (United States)

    Nole, Gabriele; Lasaponara, Rosa

    2015-04-01

    Up to nowadays, satellite data have become increasingly available, thus offering a low cost or even free of charge unique tool, with a great potential for operational monitoring of vegetation cover, quantitative assessment of urban expansion and urban sprawl, as well as for monitoring of land use changes and soil consumption. This growing observational capacity has also highlighted the need for research efforts aimed at exploring the potential offered by data processing methods and algorithms, in order to exploit as much as possible this invaluable space-based data source. The work herein presented concerns an application study on the monitoring of vegetation cover and urban sprawl conducted with the use of satellite Landsat TM data. The selected test site is the Iguazu park highly significant, being it one of the most threatened global conservation priorities (http://whc.unesco.org/en/list/303/). In order to produce synthetic maps of the investigated areas to monitor the status of vegetation and ongoing subtle changes, satellite Landsat TM data images were classified using two automatic classifiers, Maximum Likelihood (MLC) and Support Vector Machines (SVMs) applied by changing setting parameters, with the aim to compare their respective performances in terms of robustness, speed and accuracy. All process steps have been developed integrating Geographical Information System and Remote Sensing, and adopting free and open source software. Results pointed out that the SVM classifier with RBF kernel was generally the best choice (with accuracy higher than 90%) among all the configurations compared, and the use of multiple bands globally improves classification. One of the critical elements found in the case of monitoring of urban area expansion is given by the presence of urban garden mixed with urban fabric. The use of different configurations for the SVMs, i.e. different kernels and values of the setting parameters, allowed us to calibrate the classifier also to

  6. 30-kW SEP Spacecraft as Secondary Payloads for Low-Cost Deep Space Science Missions

    Science.gov (United States)

    Brophy, John R.; Larson, Tim

    2013-01-01

    The Solar Array System contracts awarded by NASA's Space Technology Mission Directorate are developing solar arrays in the 30 kW to 50 kW power range (beginning of life at 1 AU) that have significantly higher specific powers (W/kg) and much smaller stowed volumes than conventional rigid-panel arrays. The successful development of these solar array technologies has the potential to enable new types of solar electric propulsion (SEP) vehicles and missions. This paper describes a 30-kW electric propulsion vehicle built into an EELV Secondary Payload Adapter (ESPA) ring. The system uses an ESPA ring as the primary structure and packages two 15-kW Megaflex solar array wings, two 14-kW Hall thrusters, a hydrazine Reaction Control Subsystem (RCS), 220 kg of xenon, 26 kg of hydrazine, and an avionics module that contains all of the rest of the spacecraft bus functions and the instrument suite. Direct-drive is used to maximize the propulsion subsystem efficiency and minimize the resulting waste heat and required radiator area. This is critical for packaging a high-power spacecraft into a very small volume. The fully-margined system dry mass would be approximately 1120 kg. This is not a small dry mass for a Discovery-class spacecraft, for example, the Dawn spacecraft dry mass was only about 750 kg. But the Dawn electric propulsion subsystem could process a maximum input power of 2.5 kW, and this spacecraft would process 28 kW, an increase of more than a factor of ten. With direct-drive the specific impulse would be limited to about 2,000 s assuming a nominal solar array output voltage of 300 V. The resulting spacecraft would have a beginning of life acceleration that is more than an order of magnitude greater than the Dawn spacecraft. Since the spacecraft would be built into an ESPA ring it could be launched as a secondary payload to a geosynchronous transfer orbit significantly reducing the launch costs for a planetary spacecraft. The SEP system would perform the escape

  7. Anxiety disorders, major depressive disorder and the dynamic relationship between these conditions: treatment patterns and cost analysis.

    Science.gov (United States)

    François, Clément; Despiégel, Nicolas; Maman, Khaled; Saragoussi, Delphine; Auquier, Pascal

    2010-03-01

    To determine the treatment pattern and impact on healthcare costs of anxiety disorders and major depressive disorder (MDD), and influence of their concomitance and subsequence. A retrospective cohort study was conducted using a US reimbursement claims database. Adult patients with an incident diagnosis of anxiety or MDD (index date) were included. Their sociodemographic data, diagnoses, healthcare resource use and associated costs were collected over the 6 months preceding and 12 months following index date. A total of 599,624 patients were identified and included. Patients with phobia or post-traumatic stress disorder had the highest 12-month costs ($8,442 and $8,383, respectively). Patients with social anxiety disorder had the lowest costs ($3,772); generalized anxiety disorder ($6,472) incurred costs similar to MDD ($7,170). Costs were substantially increased with emergence of anxiety during follow-up in MDD patients ($10,031) or emergence of MDD in anxiety patients ($9,387). This was not observed in patients with both anxiety and MDD at index date ($6,148). This study confirms the high burden of costs of anxiety, which were within the same range as MDD. Interestingly, the emergence of anxiety or MDD in the year following a first diagnosis of MDD or anxiety, respectively, increased costs substantially. Major limitations were short follow-up and lack of absenteeism costs.

  8. Cost and Predictors of Hospitalizations for Ambulatory Care - Sensitive Conditions Among Medicaid Enrollees in Comprehensive Managed Care Plans

    Directory of Open Access Journals (Sweden)

    William N. Mkanta

    2016-09-01

    Full Text Available Introduction: Preventable hospitalizations are responsible for increasing the cost of health care and reflect ineffectiveness of the health services in the primary care setting. The objective of this study was to assess expenditure for hospitalizations and utilize expenditure differentials to determine factors associated with ambulatory care - sensitive conditions (ACSCs hospitalizations. Methods: A cross-sectional study of hospitalizations among Medicaid enrollees in comprehensive managed care plans in 2009 was conducted. A total of 25 581 patients were included in the analysis. Expenditures on hospitalizations were examined at the 50th, 75th, 90th, and 95th expenditure percentiles both at the bivariate level and in the logistic regression model to determine the impact of differing expenditure on ACSC hospitalizations. Results: Compared with patients without ACSC admissions, a larger proportion of patients with ACSC hospitalizations required advanced treatment or died on admission. Overall mean expenditures were higher for the ACSC group than for non-ACSC group (US$18 070 vs US$14 452. Whites and blacks had higher expenditures for ACSC hospitalization than Hispanics at all expenditure percentiles. Patient’s age remained a consistent predictor of ACSC hospitalization across all expenditure percentiles. Patients with ACSC were less likely to have a procedure on admission; however, the likelihood decreased as expenditure percentiles increased. At the median expenditure, blacks and Hispanics were more likely than other race/ethnic groups to have ACSC hospitalizations (odds ratio [OR]: 1.307, 95% confidence interval [CI]: 1.013-1.686 and OR 1.252, 95% CI: 1.060-1.479, respectively. Conclusion: Future review of delivery and monitoring of services at the primary care setting should include managed care plans in order to enhance access and overall quality of care for optimal utilization of the resources.

  9. Opened athletic-educational space - the condition of professional development of future teacher of physical culture is needed

    Directory of Open Access Journals (Sweden)

    Dragnev Y.V.

    2012-04-01

    Full Text Available It is shown that the opening of the sports and educational space is determined by the whole space, where the interaction of the activity of the pedagogical university with different educational institutions on the basis of integration, continuity of the educational process, aimed at physical education, the development of children and young people take place. It is revealed the importance of awareness of such concepts as the world educational space, the international educational space, the European higher education area, European space of higher education and educational space of the CIS countries.

  10. Low-Cost Manufacturing Technique for Advanced Regenerative Cooling for In-Space Cryogenic Engines, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of the proposed effort is to use selective laser melting (SLM, an additive manufacturing technique) to manufacture a hot fire-capable, water-cooled spool...

  11. Low-Cost Manufacturing Technique for Advanced Regenerative Cooling for In-Space Cryogenic Engines, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of the proposed effort is to demonstrate feasibility of using selective laser melting (SLM, an emerging manufacturing technique) to manufacture a subscale...

  12. Comet Hitchhiker: Harvesting Kinetic Energy from Small Bodies to Enable Fast and Low-Cost Deep Space Exploration

    Data.gov (United States)

    National Aeronautics and Space Administration — This idea can be intuitively understood by the analogy of fishing. Imagine a fisherman on a small boat tries to catch a big fish that runs at a high relative speed....

  13. Individual quality and age but not environmental or social conditions modulate costs of reproduction in a capital breeder

    OpenAIRE

    Debeffe, Lucie; Poissant, Jocelyn; McLoughlin, Philip D.

    2017-01-01

    Abstract Costs associated with reproduction are widely known to play a role in the evolution of reproductive tactics with consequences to population and eco?evolutionary dynamics. Evaluating these costs as they pertain to species in the wild remains an important goal of evolutionary ecology. Individual heterogeneity, including differences in individual quality (i.e., among?individual differences in traits associated with survival and reproduction) or state, and variation in environmental and ...

  14. SIMULATION FROM ENDPOINT-CONDITIONED, CONTINUOUS-TIME MARKOV CHAINS ON A FINITE STATE SPACE, WITH APPLICATIONS TO MOLECULAR EVOLUTION.

    Science.gov (United States)

    Hobolth, Asger; Stone, Eric A

    2009-09-01

    Analyses of serially-sampled data often begin with the assumption that the observations represent discrete samples from a latent continuous-time stochastic process. The continuous-time Markov chain (CTMC) is one such generative model whose popularity extends to a variety of disciplines ranging from computational finance to human genetics and genomics. A common theme among these diverse applications is the need to simulate sample paths of a CTMC conditional on realized data that is discretely observed. Here we present a general solution to this sampling problem when the CTMC is defined on a discrete and finite state space. Specifically, we consider the generation of sample paths, including intermediate states and times of transition, from a CTMC whose beginning and ending states are known across a time interval of length T. We first unify the literature through a discussion of the three predominant approaches: (1) modified rejection sampling, (2) direct sampling, and (3) uniformization. We then give analytical results for the complexity and efficiency of each method in terms of the instantaneous transition rate matrix Q of the CTMC, its beginning and ending states, and the length of sampling time T. In doing so, we show that no method dominates the others across all model specifications, and we give explicit proof of which method prevails for any given Q, T, and endpoints. Finally, we introduce and compare three applications of CTMCs to demonstrate the pitfalls of choosing an inefficient sampler.

  15. A Narrow-Linewidth Atomic Line Filter for Free Space Quantum Key Distribution under Daytime Atmospheric Conditions

    Science.gov (United States)

    Brown, Justin; Woolf, David; Hensley, Joel

    2016-05-01

    Quantum key distribution can provide secure optical data links using the established BB84 protocol, though solar backgrounds severely limit the performance through free space. Several approaches to reduce the solar background include time-gating the photon signal, limiting the field of view through geometrical design of the optical system, and spectral rejection using interference filters. Despite optimization of these parameters, the solar background continues to dominate under daytime atmospheric conditions. We demonstrate an improved spectral filter by replacing the interference filter (Δν ~ 50 GHz) with an atomic line filter (Δν ~ 1 GHz) based on optical rotation of linearly polarized light through a warm Rb vapor. By controlling the magnetic field and the optical depth of the vapor, a spectrally narrow region can be transmitted between crossed polarizers. We find that the transmission is more complex than a single peak and evaluate peak transmission as well as a ratio of peak transmission to average transmission of the local spectrum. We compare filters containing a natural abundance of Rb with those containing isotopically pure 87 Rb and 85 Rb. A filter providing > 95 % transmission and Δν ~ 1.1 GHz is achieved.

  16. Space Station: NASA's software development approach increases safety and cost risks. Report to the Chairman, Committee on Science, Space, and Technology, House of Representatives

    Science.gov (United States)

    1992-06-01

    The House Committee on Science, Space, and Technology asked NASA to study software development issues for the space station. How well NASA has implemented key software engineering practices for the station was asked. Specifically, the objectives were to determine: (1) if independent verification and validation techniques are being used to ensure that critical software meets specified requirements and functions; (2) if NASA has incorporated software risk management techniques into program; (3) whether standards are in place that will prescribe a disciplined, uniform approach to software development; and (4) if software support tools will help, as intended, to maximize efficiency in developing and maintaining the software. To meet the objectives, NASA proceeded: (1) reviewing and analyzing software development objectives and strategies contained in NASA conference publications; (2) reviewing and analyzing NASA, other government, and industry guidelines for establishing good software development practices; (3) reviewing and analyzing technical proposals and contracts; (4) reviewing and analyzing software management plans, risk management plans, and program requirements; (4) reviewing and analyzing reports prepared by NASA and contractor officials that identified key issues and challenges facing the program; (5) obtaining expert opinions on what constitutes appropriate independent V-and-V and software risk management activities; (6) interviewing program officials at NASA headquarters in Washington, DC; at the Space Station Program Office in Reston, Virginia; and at the three work package centers; Johnson in Houston, Texas; Marshall in Huntsville, Alabama; and Lewis in Cleveland, Ohio; and (7) interviewing contractor officials doing work for NASA at Johnson and Marshall. The audit work was performed in accordance with generally accepted government auditing standards, between April 1991 and May 1992.

  17. Impact of comorbid conditions in COPD patients on health care resource utilization and costs in a predominantly Medicare population

    Directory of Open Access Journals (Sweden)

    Schwab P

    2017-02-01

    Full Text Available Phil Schwab,1 Amol D Dhamane,2 Sari D Hopson,1 Chad Moretz,1 Srinivas Annavarapu,1 Kate Burslem,2 Andrew Renda,3 Shuchita Kaila2 1Comprehensive Health Insights Inc., Louisville, KY, 2Health Economics and Outcomes Research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, 3Humana Inc., Louisville, KY, USA Background: Patients with chronic obstructive pulmonary disease (COPD often have multiple underlying comorbidities, which may lead to increased health care resource utilization (HCRU and costs.Objective: To describe the comorbidity profiles of COPD patients and examine the associations between the presence of comorbidities and HCRU or health care costs.Methods: A retrospective cohort study utilizing data from a large US national health plan with a predominantly Medicare population was conducted. COPD patients aged 40–89 years and continuously enrolled for 12 months prior to and 24 months after the first COPD diagnosis during the period of January 01, 2009, through December 31, 2010, were selected. Eleven comorbidities of interest were identified 12 months prior through 12 months after COPD diagnosis. All-cause and COPD-related hospitalizations and costs were assessed 24 months after diagnosis, and the associations with comorbidities were determined using multivariate statistical models.Results: Ninety-two percent of 52,643 COPD patients identified had at least one of the 11 comorbidities. Congestive heart failure (CHF, coronary artery disease, and cerebrovascular disease (CVA had the strongest associations with all-cause hospitalizations (mean ratio: 1.56, 1.32, and 1.30, respectively; P<0.0001; other comorbidities examined had moderate associations. CHF, anxiety, and sleep apnea had the strongest associations with COPD-related hospitalizations (mean ratio: 2.01, 1.32, and 1.21, respectively; P<0.0001; other comorbidities examined (except chronic kidney disease [CKD], obesity, and osteoarthritis had moderate associations. All

  18. Cost-effectiveness of manual therapy for the management of musculoskeletal conditions: a systematic review and narrative synthesis of evidence from randomized controlled trials.

    Science.gov (United States)

    Tsertsvadze, Alexander; Clar, Christine; Court, Rachel; Clarke, Aileen; Mistry, Hema; Sutcliffe, Paul

    2014-01-01

    The purpose of this study was to systematically review trial-based economic evaluations of manual therapy relative to other alternative interventions used for the management of musculoskeletal conditions. A comprehensive literature search was undertaken in major medical, health-related, science and health economic electronic databases. Twenty-five publications were included (11 trial-based economic evaluations). The studies compared cost-effectiveness and/or cost-utility of manual therapy interventions to other treatment alternatives in reducing pain (spinal, shoulder, ankle). Manual therapy techniques (e.g., osteopathic spinal manipulation, physiotherapy manipulation and mobilization techniques, and chiropractic manipulation with or without other treatments) were more cost-effective than usual general practitioner (GP) care alone or with exercise, spinal stabilization, GP advice, advice to remain active, or brief pain management for improving low back and shoulder pain/disability. Chiropractic manipulation was found to be less costly and more effective than alternative treatment compared with either physiotherapy or GP care in improving neck pain. Preliminary evidence from this review shows some economic advantage of manual therapy relative to other interventions used for the management of musculoskeletal conditions, indicating that some manual therapy techniques may be more cost-effective than usual GP care, spinal stabilization, GP advice, advice to remain active, or brief pain management for improving low back and shoulder pain/disability. However, at present, there is a paucity of evidence on the cost-effectiveness and/or cost-utility evaluations for manual therapy interventions. Further improvements in the methodological conduct and reporting quality of economic evaluations of manual therapy are warranted in order to facilitate adequate evidence-based decisions among policy makers, health care practitioners, and patients. Copyright © 2014 National University

  19. Assessment of management alternatives for LWR wastes. Volume 6. Cost determination of the LWR waste management routes (treatment/conditioning/packaging/transport operations)

    International Nuclear Information System (INIS)

    Thiels, G.M.; Kowa, S.

    1993-01-01

    This report deals with the cost determination of a number of schemes for the treatment, conditioning, packaging, interim storage and transport operations of LWR wastes drawn up on the basis of Belgian, French and German practices in this particular area. In addition to the general procedure elaborated for determining, actualizing and scaling of plant and transport costs associated with the various schemes, in-depth calculations of each intermediate management stage are included in this report. This study is part of an overall theoretical exercise aimed at evaluating a selection of management routes for LWR waste based on economical and radiological criteria

  20. Optimal replacement of residential air conditioning equipment to minimize energy, greenhouse gas emissions, and consumer cost in the US

    International Nuclear Information System (INIS)

    De Kleine, Robert D.; Keoleian, Gregory A.; Kelly, Jarod C.

    2011-01-01

    A life cycle optimization of the replacement of residential central air conditioners (CACs) was conducted in order to identify replacement schedules that minimized three separate objectives: life cycle energy consumption, greenhouse gas (GHG) emissions, and consumer cost. The analysis was conducted for the time period of 1985-2025 for Ann Arbor, MI and San Antonio, TX. Using annual sales-weighted efficiencies of residential CAC equipment, the tradeoff between potential operational savings and the burdens of producing new, more efficient equipment was evaluated. The optimal replacement schedule for each objective was identified for each location and service scenario. In general, minimizing energy consumption required frequent replacement (4-12 replacements), minimizing GHG required fewer replacements (2-5 replacements), and minimizing cost required the fewest replacements (1-3 replacements) over the time horizon. Scenario analysis of different federal efficiency standards, regional standards, and Energy Star purchases were conducted to quantify each policy's impact. For example, a 16 SEER regional standard in Texas was shown to either reduce primary energy consumption 13%, GHGs emissions by 11%, or cost by 6-7% when performing optimal replacement of CACs from 2005 or before. The results also indicate that proper servicing should be a higher priority than optimal replacement to minimize environmental burdens. - Highlights: → Optimal replacement schedules for residential central air conditioners were found. → Minimizing energy required more frequent replacement than minimizing consumer cost. → Significant variation in optimal replacement was observed for Michigan and Texas. → Rebates for altering replacement patterns are not cost effective for GHG abatement. → Maintenance levels were significant in determining the energy and GHG impacts.

  1. Differences between dentitions with palatally and labially located maxillary canines observed in incisor width, dental morphology and space conditions

    DEFF Research Database (Denmark)

    Artmann, L; Larsen, H J; Sørensen, H B

    2010-01-01

    To analyze the interrelationship between incisor width, deviations in the dentition and available space in the dental arch in palatally and labially located maxillary ectopic canine cases.......To analyze the interrelationship between incisor width, deviations in the dentition and available space in the dental arch in palatally and labially located maxillary ectopic canine cases....

  2. The Optimization of the Time-Cost Tradeoff Problem in Projects with Conditional Activities Using of the Multi-Objective Charged System Search Algorithm (SMOCSS

    Directory of Open Access Journals (Sweden)

    M. K. Sharbatdar

    2016-11-01

    Full Text Available Abstract The appropriate planning and scheduling for reaching the project goals in the most economical way is the very basic issue of the project management. As in each project, the project manager must determine the required activities for the implementation of the project and select the best option in the implementation of each of the activities, in a way that the least final cost and time of the project is achieved. Considering the number of activities and selecting options for each of the activities, usually the selection has not one unique solution, but it consists of a set of solutions that are not preferred to each other and are known as Pareto solutions. On the other hand, in some actual projects, there are activities that their implementation options depend on the implementation of the prerequisite activity and are not applicable using all the implementation options, and even in some cases the implementation or the non-implementation of some activities are also dependent on the prerequisite activity implementation. These projects can be introduced as conditional projects. Much researchs have been conducted for acquiring Pareto solution set, using different methods and algorithms, but in all the done tasks the time-cost optimization of conditional projects is not considered. Thus, in the present study the concept of conditional network is defined along with some practical examples, then an appropriate way to illustrate these networks and suitable time-cost formulation of these are presented. Finally, for some instances of conditional activity networks, conditional project time-cost optimization conducted multi-objectively using known meta-heuristic algorithms such as multi-objective genetic algorithm, multi-objective particle swarm algorithm and multi-objective charged system search algorithm.

  3. A condition-based maintenance policy for multi-component systems with a high maintenance setup cost

    NARCIS (Netherlands)

    Zhu, Q.; Peng, H.; Houtum, van G.J.J.A.N.

    2015-01-01

    Condition-based maintenance (CBM) is becoming increasingly important due to the development of advanced sensor and information technology, which facilitates the remote collection of condition data. We propose a new CBM policy for multi-component systems with continuous stochastic deteriorations. To

  4. A condition-based maintenance policy for multi-component systems with a high maintenance setup cost

    NARCIS (Netherlands)

    Zhu, Q.; Peng, H.; Houtum, van G.J.J.A.N.

    2012-01-01

    Condition-based maintenance (CBM) is becoming increasingly important due to the development of advanced sensor and ICT technology, so that the condition data can be collected remotely. We propose a new CBM policy for multi-component systems with continuous stochastic deteriorations. To reduce the

  5. The interaction between reproductive cost and individual quality is mediated by oceanic conditions in a long-lived bird.

    Science.gov (United States)

    Robert, Alexandre; Paiva, Vitor H; Bolton, Mark; Jiguet, Frédéric; Bried, Joël

    2012-08-01

    Environmental variability, costs of reproduction, and heterogeneity in individual quality are three important sources of the temporal and interindividual variations in vital rates of wild populations. Based on an 18-year monitoring of an endangered, recently described, long-lived seabird, Monteiro's Storm-Petrel (Oceanodroma monteiroi), we designed multistate survival models to separate the effects of the reproductive cost (breeders vs. nonbreeders) and individual quality (successful vs. unsuccessful breeders) in relation to temporally variable demographic and oceanographic properties. The analysis revealed a gradient of individual quality from nonbreeders, to unsuccessful breeders, to successful breeders. The survival rates of unsuccessful breeders (0.90 +/- 0.023, mean +/- SE) tended to decrease in years of high average breeding success and were more sensitive to oceanographic variation than those of both (high-quality) successful breeders (0.97 +/- 0.015) and (low-quality) nonbreeders (0.83 +/- 0.028). Overall, our results indicate that reproductive costs act on individuals of intermediate quality and are mediated by environmental harshness.

  6. Preparation, characterization and environmental/electrochemical energy storage testing of low-cost biochar from natural chitin obtained via pyrolysis at mild conditions

    Science.gov (United States)

    Magnacca, Giuliana; Guerretta, Federico; Vizintin, Alen; Benzi, Paola; Valsania, Maria C.; Nisticò, Roberto

    2018-01-01

    Chitin (a biopolymer obtained from shellfish industry) was used as precursor for the production of biochars obtained via pyrolysis treatments performed at mild conditions (in the 290-540 °C range). Biochars were physicochemical characterized in order to evaluate the pyrolysis-induced effects in terms of both functional groups and material structure. Moreover, such carbonaceous materials were tested as adsorbent substrates for the removal of target molecules from aqueous environment as well as in solid-gas experiments, to measure the adsorption capacities and selectivity toward CO2. Lastly, biochars were also investigated as possible cathode materials in sustainable and low-cost electrochemical energy storage devices, such as lithium-sulphur (Li-S) batteries. Interestingly, experimental results evidenced that such chitin-derived biochars obtained via pyrolysis at mild conditions are sustainable, low-cost and easy scalable alternative materials suitable for both environmental and energetic applications.

  7. A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions.

    Science.gov (United States)

    Cheung, C Y Maurice; Williams, Thomas C R; Poolman, Mark G; Fell, David A; Ratcliffe, R George; Sweetlove, Lee J

    2013-09-01

    Flux balance models of metabolism generally utilize synthesis of biomass as the main determinant of intracellular fluxes. However, the biomass constraint alone is not sufficient to predict realistic fluxes in central heterotrophic metabolism of plant cells because of the major demand on the energy budget due to transport costs and cell maintenance. This major limitation can be addressed by incorporating transport steps into the metabolic model and by implementing a procedure that uses Pareto optimality analysis to explore the trade-off between ATP and NADPH production for maintenance. This leads to a method for predicting cell maintenance costs on the basis of the measured flux ratio between the oxidative steps of the oxidative pentose phosphate pathway and glycolysis. We show that accounting for transport and maintenance costs substantially improves the accuracy of fluxes predicted from a flux balance model of heterotrophic Arabidopsis cells in culture, irrespective of the objective function used in the analysis. Moreover, when the new method was applied to cells under control, elevated temperature and hyper-osmotic conditions, only elevated temperature led to a substantial increase in cell maintenance costs. It is concluded that the hyper-osmotic conditions tested did not impose a metabolic stress, in as much as the metabolic network is not forced to devote more resources to cell maintenance. © 2013 The Authors The Plant Journal © 2013 John Wiley & Sons Ltd.

  8. Space space space

    CERN Document Server

    Trembach, Vera

    2014-01-01

    Space is an introduction to the mysteries of the Universe. Included are Task Cards for independent learning, Journal Word Cards for creative writing, and Hands-On Activities for reinforcing skills in Math and Language Arts. Space is a perfect introduction to further research of the Solar System.

  9. New airborne pathogen transport model for upper-room UVGI spaces conditioned by chilled ceiling and mixed displacement ventilation: Enhancing air quality and energy performance

    International Nuclear Information System (INIS)

    Kanaan, Mohamad; Ghaddar, Nesreen; Ghali, Kamel; Araj, Georges

    2014-01-01

    Highlights: • A model of bacteria transport is developed in CC/DV conditioned spaces with UVGI. • The model identifies buoyant, partially mixed, and fully mixed transport zones. • The predicted bacteria concentration agreed well with CFD results. • The higher the supply flow rate, the more restrictive is return air mixing ratio. • Upper-room UVGI results in higher return mixing and 33% in energy savings. - Abstract: The maximum allowable return air ratio in chilled ceiling (CC) and mixed displacement ventilation (DV) system for good air quality is regulated by acceptable levels of CO 2 concentration not to exceed 700 ppm and airborne bacterial count to satisfy World Health Organization (WHO) requirement for bacterial count not to exceed 500 CFU/m 3 . Since the CC/DV system relies on buoyancy effects for driving the contaminated air upwards, infectious particles will recirculate in the upper zone allowing effective utilization of upper-room ultraviolet germicidal irradiation (UVGI) to clean return air. The aim of this work is to develop a new airborne bacteria transport plume-multi-layer zonal model at low computational cost to predict bacteria concentration distribution in mixed CC/DV conditioned room without and with upper-room UVGI installed. The results of the simplified model were compared with layer-averaged concentration predictions of a detailed and experimentally-validated 3-D computational fluid dynamics (CFD) model. The comparison showed good agreement between bacteria transport model results and CFD predictions of room air bacteria concentration with maximum error of ±10.4 CFU/m 3 in exhaust air. The simplified model captured the vertical bacteria concentration distribution in room air as well as the locking effect of highest concentration happening at the stratification level. The developed bacteria transport model was used in a case study to determine the return air mixing ratio that minimizes energy consumption and maintains acceptable IAQ

  10. Whether and under what conditions FDG-PET might be cost-effective in evaluating solitary pulmonary nodules depicted on lung cancer screening in Japan

    International Nuclear Information System (INIS)

    Tsushima, Yoshito; Aoki, Jun; Endo, Keigo

    2003-01-01

    The purpose of this study was to determine whether and under what conditions fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) may be cost-effective in evaluating solitary pulmonary nodules depicted on lung cancer screening in Japan. Three decision models for differentiating lung cancer from benign nodules were compared: CT alone, PET alone, and CT plus PET. The various paths of each strategy were dependent on variables determined from a review of the medical literature. Costs were based on Japanese health insurance. The prevalence of lung cancer among solitary pulmonary nodules detected on lung cancer screening was less than 10%. For this prevalence, the CT-plus-PET model was the cost-effective alternative to the CT-alone model (cost savings were 64,000 yen per patient) and provided greater accuracy (0.90 vs. 0.84). Both of these effects were the result of reducing the number of candidates who undergo unnecessary CT-guided or bronchofiberscopic biopsies or thoracotomy for a benign pulmonary nodule. The CT-plus-PET strategy is accurate and cost-effective for the characterization of solitary pulmonary nodules detected on lung cancer screening in Japan. (author)

  11. Costs, effects and implementation of routine data emergency admission risk prediction models in primary care for patients with, or at risk of, chronic conditions: a systematic review protocol.

    Science.gov (United States)

    Kingston, Mark Rhys; Evans, Bridie Angela; Nelson, Kayleigh; Hutchings, Hayley; Russell, Ian; Snooks, Helen

    2016-03-01

    Emergency admission risk prediction models are increasingly used to identify patients, typically with one or more chronic conditions, for proactive management in primary care to avoid admissions, save costs and improve patient experience. To identify and review the published evidence on the costs, effects and implementation of emergency admission risk prediction models in primary care for patients with, or at risk of, chronic conditions. We shall search for studies of healthcare interventions using routine data-generated emergency admission risk models. We shall report: the effects on emergency admissions and health costs; clinician and patient views; and implementation findings. We shall search ASSIA, CINAHL, the Cochrane Library, HMIC, ISI Web of Science, MEDLINE and Scopus from 2005, review references in and citations of included articles, search key journals and contact experts. Study selection, data extraction and quality assessment will be performed by two independent reviewers. No ethical permissions are required for this study using published data. Findings will be disseminated widely, including publication in a peer-reviewed journal and through conferences in primary and emergency care and chronic conditions. We judge our results will help a wide audience including primary care practitioners and commissioners, and policymakers. CRD42015016874; Pre-results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  12. An improved, low-cost, hydroponic system for growing Arabidopsis and other plant species under aseptic conditions.

    Science.gov (United States)

    Alatorre-Cobos, Fulgencio; Calderón-Vázquez, Carlos; Ibarra-Laclette, Enrique; Yong-Villalobos, Lenin; Pérez-Torres, Claudia-Anahí; Oropeza-Aburto, Araceli; Méndez-Bravo, Alfonso; González-Morales, Sandra-Isabel; Gutiérrez-Alanís, Dolores; Chacón-López, Alejandra; Peña-Ocaña, Betsy-Anaid; Herrera-Estrella, Luis

    2014-03-21

    Hydroponics is a plant growth system that provides a more precise control of growth media composition. Several hydroponic systems have been reported for Arabidopsis and other model plants. The ease of system set up, cost of the growth system and flexibility to characterize and harvest plant material are features continually improved in new hydroponic system reported. We developed a hydroponic culture system for Arabidopsis and other model plants. This low cost, proficient, and novel system is based on recyclable and sterilizable plastic containers, which are readily available from local suppliers. Our system allows a large-scale manipulation of seedlings. It adapts to different growing treatments and has an extended growth window until adult plants are established. The novel seed-holder also facilitates the transfer and harvest of seedlings. Here we report the use of our hydroponic system to analyze transcriptomic responses of Arabidopsis to nutriment availability and plant/pathogen interactions. The efficiency and functionality of our proposed hydroponic system is demonstrated in nutrient deficiency and pathogenesis experiments. Hydroponically grown Arabidopsis seedlings under long-time inorganic phosphate (Pi) deficiency showed typical changes in root architecture and high expression of marker genes involved in signaling and Pi recycling. Genome-wide transcriptional analysis of gene expression of Arabidopsis roots depleted of Pi by short time periods indicates that genes related to general stress are up-regulated before those specific to Pi signaling and metabolism. Our hydroponic system also proved useful for conducting pathogenesis essays, revealing early transcriptional activation of pathogenesis-related genes.

  13. Cost comparisons

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    How much does the LHC cost? And how much does this represent in other currencies? Below we present a table showing some comparisons with the cost of other projects. Looking at the figures, you will see that the cost of the LHC can be likened to that of three skyscrapers, or two seasons of Formula 1 racing! One year's budget of a single large F1 team is comparable to the entire materials cost of the ATLAS or CMS experiments.   Please note that all the figures are rounded for ease of reading.    CHF € $   LHC 4.6 billions 3 billions  4 billions   Space Shuttle Endeavour (NASA) 1.9 billion 1.3 billion 1.7 billion   Hubble Space Telescope (cost at launch – NASA/...

  14. Paternal care decreases foraging activity and body condition, but does not impose survival costs to caring males in a Neotropical arachnid.

    Science.gov (United States)

    Requena, Gustavo S; Buzatto, Bruno A; Martins, Eduardo G; Machado, Glauco

    2012-01-01

    Exclusive paternal care is the rarest form of parental investment in nature and theory predicts that the maintenance of this behavior depends on the balance between costs and benefits to males. Our goal was to assess costs of paternal care in the harvestman Iporangaia pustulosa, for which the benefits of this behavior in terms of egg survival have already been demonstrated. We evaluated energetic costs and mortality risks associated to paternal egg-guarding in the field. We quantified foraging activity of males and estimated how their body condition is influenced by the duration of the caring period. Additionally, we conducted a one-year capture-mark-recapture study and estimated apparent survival probabilities of caring and non-caring males to assess potential survival costs of paternal care. Our results indicate that caring males forage less frequently than non-caring individuals (males and females) and that their body condition deteriorates over the course of the caring period. Thus, males willing to guard eggs may provide to females a fitness-enhancing gift of cost-free care of their offspring. Caring males, however, did not show lower survival probabilities when compared to both non-caring males and females. Reduction in mortality risks as a result of remaining stationary, combined with the benefits of improving egg survival, may have played an important and previously unsuspected role favoring the evolution of paternal care. Moreover, males exhibiting paternal care could also provide an honest signal of their quality as offspring defenders, and thus female preference for caring males could be responsible for maintaining the trait.

  15. Paternal care decreases foraging activity and body condition, but does not impose survival costs to caring males in a Neotropical arachnid.

    Directory of Open Access Journals (Sweden)

    Gustavo S Requena

    Full Text Available Exclusive paternal care is the rarest form of parental investment in nature and theory predicts that the maintenance of this behavior depends on the balance between costs and benefits to males. Our goal was to assess costs of paternal care in the harvestman Iporangaia pustulosa, for which the benefits of this behavior in terms of egg survival have already been demonstrated. We evaluated energetic costs and mortality risks associated to paternal egg-guarding in the field. We quantified foraging activity of males and estimated how their body condition is influenced by the duration of the caring period. Additionally, we conducted a one-year capture-mark-recapture study and estimated apparent survival probabilities of caring and non-caring males to assess potential survival costs of paternal care. Our results indicate that caring males forage less frequently than non-caring individuals (males and females and that their body condition deteriorates over the course of the caring period. Thus, males willing to guard eggs may provide to females a fitness-enhancing gift of cost-free care of their offspring. Caring males, however, did not show lower survival probabilities when compared to both non-caring males and females. Reduction in mortality risks as a result of remaining stationary, combined with the benefits of improving egg survival, may have played an important and previously unsuspected role favoring the evolution of paternal care. Moreover, males exhibiting paternal care could also provide an honest signal of their quality as offspring defenders, and thus female preference for caring males could be responsible for maintaining the trait.

  16. The Costs of Parental Pressure to Express Emotions: Conditional Regard and Autonomy Support as Predictors of Emotion Regulation and Intimacy

    Science.gov (United States)

    Roth, Guy; Assor, Avi

    2012-01-01

    This research focuses on offspring's perceptions of their parents' usage of conditional regard and autonomy-supportive practices in response to the offspring's experiences of negative emotion. Participants were 174 college students (60% were females). As predicted from self-determination theory (Ryan & Deci, 2000), students' perceptions of parents…

  17. Examining the Costs and Benefits of Family Rewards 2.0: A Conditional Cash Transfer Program in Two American Cities

    Science.gov (United States)

    Rudd, Timothy; Rodriguez, Jonathan; Greenberg, David

    2016-01-01

    Family Rewards was an innovative approach to poverty reduction in the United States that was modelled on the conditional cash transfer (CCT) programs common in lower- and middle-income countries. The program offered cash assistance to poor families to reduce immediate hardship, provided they met certain criteria related to family health care,…

  18. Energy vulnerability. Far from urban centres, space heating and fuel costs weigh heavily on the household budget

    International Nuclear Information System (INIS)

    Cochez, Nicolas; Durieux, Eric; Levy, David; Moreau, Sylvain; Baudu-Baret, Claude

    2015-01-01

    For 15% of resident households in metropolitan France, the proportion of income going on home and water heating is high, in the sense that it is twice the median housing-expense to income ratio. With this same criterion, the cost of the most mandatory car journeys is high for 10% of households, in relation to their budgets. In all, 22% of households (i.e. 5.9 million) are experiencing energy vulnerability for one or other of the items of consumption, and 3% of households (i.e. 700 000) are vulnerable for both items. The risk of vulnerability varies over national territory, with differences depending on the items of expenditure considered: climate is the primary factor where disparity in housing-related vulnerability is concerned, whereas the predominant factor for travel is distance from urban centres

  19. Development of a bio-chip dedicated to planetary exploration. First step: resistance studies to space conditions

    International Nuclear Information System (INIS)

    Le Postollec, A.; Dobrijevic, M.; Incerti, S.; Moretto, Ph.; Seznec, H.; Desorgher, L.; Santin, G.; Nieminen, P.; Dartnell, L.; Vandenabeele-Trambouze, O.; Coussot, G.

    2008-02-01

    For upcoming exploration missions, space agencies advocate the development of a new promising technique to search for traces of extent or extinct life: the bio-chip use. A bio-chip is a miniaturized device composed of biological sensitive systems fixed on a solid substrate. As space is a hazardous environment, a main concern relies on the resistance of a bio-chip to a panel of harsh constraints among which the resistance to radiations. Within the framework of the BiOMAS (Bio-chip for Organic Matter Analysis in Space) project, our team is currently developing a bio-chip especially designed for planetary exploration. We present here the methodology adopted and the beginning experiments to select the best constituents, to determine resistance levels and to define well-adapted protection for the bio-chip

  20. Effect of space availability at feed bunk and rest area on metabolic conditions and productive responses in dairy cows

    Directory of Open Access Journals (Sweden)

    L. Stefanini

    2011-03-01

    Full Text Available It has been estimated that dairy cows spend 3 to 5 h/d eating, consuming 9 to 14 meals per day. In addition, they ruminate 7 to 10 h/d, spend approximately 30 min/d drinking, 2 to 3 h/d being milked, and require approximately 10 h/d for lying time (Grant and Albright, 2000. Management decisions on dairy must not interfere with the cow’s ability to perform these activities which comprises her daily routines. It is well known that feed bunk space modifies eating behaviour, while the amount and characteristics of rest area modify resting activity of the cows. The traditional recommendation of 0.6 linear meter of bunk space per cow is the minimal amount of space needed for all cows to eat at one time (Grant and Albright, 2001.......

  1. Evolution of dislocation structures following a change in loading conditions studied by in situ high resolution reciprocal space mapping

    DEFF Research Database (Denmark)

    Wejdemann, Christian

    or to a strain of 7% at a temperature of -196 ○C, and the samples were characterized by electron microscopy and mechanical tests. Transmission electron microscopy showed that the pre-deformation produced a characteristic dislocation cell structure consisting of regions with relatively high dislocation density...... the pre-deformation axis. In the X-ray diffraction experiments a technique was employed with which it is possible to obtain high-resolution reciprocal space maps from individual bulk grains. The high-resolution reciprocal space maps contain features related to the dislocation structure in the grains......: A spread-out ‘cloud’ of low intensity caused by diffraction from the dislocation walls and a number of sharp peaks of high intensity caused by diffraction from the individual subgrains. By acquiring reciprocal space maps at a number of different strain levels the evolution of the dislocation structures can...

  2. Inter and intra row spacing effects on growth, seed yield and oil contents of white mustard (sinapis alba l.) under rainfed conditions

    International Nuclear Information System (INIS)

    Arif, M.; Shehzad, M.A.

    2012-01-01

    A field experiment was conducted to evaluate the effect of different plant densities on growth and yield of white mustard during Rabi 2008-09 under rain fed conditions. Three plant spacing (5, 10 and 15 cm) and three row spacing (10, 20 and 30 cm) were applied during the course of study. Results indicated that plant density has significant effects on growth, seed yield and oil contents of white mustard. Number of pods per plant (2002), number of seeds per pod (4.67), 1000 seed weight (5.02 g), oil contents (32.21 %) and fatty acids except linoleic acid significantly increased by increasing plant spacing due to less competition among plants for moisture, light and nutrients. The maximum plant height (148.9 cm) was with 10 X 20 cm spacing. Maximum seed yield (2046 kg ha/sup -1/) was recorded for row spacing 15 cm where plants were spaced 10 cm within rows. At higher plant density, the overall seed yield of white mustard increased with increasing number of pods per plant. Thus, it is concluded that white mustard should be grown at 150 cm grids for higher yield output. (author)

  3. The total cost of logistics in supplier selection, under conditions of multiple sourcing, multiple criteria and capacity constraint

    Directory of Open Access Journals (Sweden)

    Elnaz Bani

    2016-06-01

    Full Text Available This paper presents a mathematical model to solve a multi-objective decision making supplier selection problem. The proposed problem considers three objective functions: the first objective function minimizes the cost of purchasing the products while the second objective function minimizes the due dates and finally the third objective function maximizes the customer satisfaction. The resulted problem is formulated as mixed integer programming and, therefore, we use invasive weed optimization technique to solve the resulted problem. The performance of the proposed model is compared with NSGA II based on different criteria such as mean ideal distance and quality matrix. The preliminary results indicate that the proposed model performs relatively well compared with alternative method.

  4. Obesity-specific neural cost of maintaining gait performance under complex conditions in community-dwelling older adults.

    Science.gov (United States)

    Osofundiya, Olufunmilola; Benden, Mark E; Dowdy, Diane; Mehta, Ranjana K

    2016-06-01

    Recent evidence of obesity-related changes in the prefrontal cortex during cognitive and seated motor activities has surfaced; however, the impact of obesity on neural activity during ambulation remains unclear. The purpose of this study was to determine obesity-specific neural cost of simple and complex ambulation in older adults. Twenty non-obese and obese individuals, 65years and older, performed three tasks varying in the types of complexity of ambulation (simple walking, walking+cognitive dual-task, and precision walking). Maximum oxygenated hemoglobin, a measure of neural activity, was measured bilaterally using a portable functional near infrared spectroscopy system, and gait speed and performance on the complex tasks were also obtained. Complex ambulatory tasks were associated with ~2-3.5 times greater cerebral oxygenation levels and ~30-40% slower gait speeds when compared to the simple walking task. Additionally, obesity was associated with three times greater oxygenation levels, particularly during the precision gait task, despite obese adults demonstrating similar gait speeds and performances on the complex gait tasks as non-obese adults. Compared to existing studies that focus solely on biomechanical outcomes, the present study is one of the first to examine obesity-related differences in neural activity during ambulation in older adults. In order to maintain gait performance, obesity was associated with higher neural costs, and this was augmented during ambulatory tasks requiring greater precision control. These preliminary findings have clinical implications in identifying individuals who are at greater risk of mobility limitations, particularly when performing complex ambulatory tasks. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Methodology of functional and cost approach to improvement of a control system of corporation in modern conditions

    Directory of Open Access Journals (Sweden)

    Zlygostev A.N.

    2017-09-01

    Full Text Available according to the author, the corporate structure of economic entities is objective need today owing to the fact that the created conditions of acceleration of economic development of the country often demand association of several legal entities and individuals conducting an entrepreneurial activity to achieve the required result. At the same time, the corporation is not independent legal form and its activity is not regulated by the Civil Code of the Russian Federation. In this regard, there is a set of various interrelations and the relations of economic entities which are based on a basis of self-government and membership of participants of corporation on long-term contractual and contract conditions. This, in turn, predetermines the search of new, most effective forms and methods of formation and development of control systems of corporations including increases in level of their personnel potential.

  6. On the Stability of Deinoxanthin Exposed to Mars Conditions during a Long-Term Space Mission and Implications for Biomarker Detection on Other Planets

    Directory of Open Access Journals (Sweden)

    Stefan Leuko

    2017-09-01

    Full Text Available Outer space, the final frontier, is a hostile and unforgiving place for any form of life as we know it. The unique environment of space allows for a close simulation of Mars surface conditions that cannot be simulated as accurately on the Earth. For this experiment, we tested the resistance of Deinococcus radiodurans to survive exposure to simulated Mars-like conditions in low-Earth orbit for a prolonged period of time as part of the Biology and Mars experiment (BIOMEX project. Special focus was placed on the integrity of the carotenoid deinoxanthin, which may serve as a potential biomarker to search for remnants of life on other planets. Survival was investigated by evaluating colony forming units, damage inflicted to the 16S rRNA gene by quantitative PCR, and the integrity and detectability of deinoxanthin by Raman spectroscopy. Exposure to space conditions had a strong detrimental effect on the survival of the strains and the 16S rRNA integrity, yet results show that deinoxanthin survives exposure to conditions as they prevail on Mars. Solar radiation is not only strongly detrimental to the survival and 16S rRNA integrity but also to the Raman signal of deinoxanthin. Samples not exposed to solar radiation showed only minuscule signs of deterioration. To test whether deinoxanthin is able to withstand the tested parameters without the protection of the cell, it was extracted from cell homogenate and exposed to high/low temperatures, vacuum, germicidal UV-C radiation, and simulated solar radiation. Results obtained by Raman investigations showed a strong resistance of deinoxanthin against outer space and Mars conditions, with the only exception of the exposure to simulated solar radiation. Therefore, deinoxanthin proved to be a suitable easily detectable biomarker for the search of Earth-like organic pigment-containing life on other planets.

  7. Space and crime in Dutch built environments : Macro and micro scale spatial conditions for residential burglaries and thefts from cars

    NARCIS (Netherlands)

    Lopez, M.J.J.; Van Nes, A.

    2007-01-01

    At this moment, more knowledge is available on the physical characteristics of the built environment and their relationship to criminal opportunity rather than the spatial characteristics of potential targets and the public and private space between them. To improve this situation, a research

  8. Effects of Row Spacing and Plant Density on Yield and Yield Components of Sweet Corn in Climatic Conditions of Isfahan

    Directory of Open Access Journals (Sweden)

    N. Khodaeian

    2013-06-01

    Full Text Available To evaluate the effects of row spacing and plant density on yield and yield components of sweet corn, variety KSC403, an experiment was conducted in Research Farm of Isfahan University of Technology, Isfahan, Iran, in 2007, as randomized complete block design with a split-plot layout and three replications. The main plots were allocated to two row spacing (60 and 75 cm and the sub-plots accommodated four levels of plant density (50000, 70000, 90000 and 110000 plants per ha. There was significant increase in leaf area index, shoot dry weight, 100-grain fresh weight and grain fresh yield, as row width was decreased from 75 to 60 cm but the plant height was decreased. There was no significant effect of row spacing on number of rows per ear, number of grains per row and number of grains per ear. Plant height, leaf area index, shoot dry weight per m2 and number of ears per m2 were increased with an increase in plant density. The number of rows per ear, number of grains per row, number of grains per ear, 100-grain fresh weight and grain fresh yield were significantly higher under plant densities of 90000 and 110000 as compared to 50000 and 70000 plants per ha. There was significant interaction between row spacing and plant density for leaf area index, shoot dry weight, number of grains per ear, 100-grain fresh weight and grain fresh yield. Under all plant densities, the grain fresh yield was higher in 60-cm row width compared to 70-cm row width. However, the difference between these two row spacing was not significant in plant densities of 50000 and 110000 plants per ha. The highest grain fresh yield (33940 kg/ha was achieved under row spacing 60 cm and 70000 plants per ha and the least grain fresh yield (20750 kg/ha was obtained in under 75 cm row width and 110000 plants per ha. Considering the obtained results of this experiment, to have maximum grain fresh yield of sweet corn under Isfahan climate, the row spacing of 60 cm and plant density of

  9. New concept for condition management of plants as a result of the KUNTO project. New operations approach reduces costs

    Energy Technology Data Exchange (ETDEWEB)

    McNiven, U.; Tamminen, L.

    1998-07-01

    IVO Generation Services Ltd. has carried out a project at the IVO Naantali power plant to develop the plants condition management. The project defines critical and monitored components for each system. In addition, recommendations for further action, investment proposals and suggestions for changes in maintenance and operations practices were supplied for the various systems in the plant. The systematic approach which was the result of the projects integrated into maintenance and operations practices where data collection and analysis is part of the routine. Up-to-date data is utilized in focusing maintenance and investments, in planning and reporting functions

  10. Acute Care Use for Ambulatory Care-Sensitive Conditions in High-Cost Users of Medical Care with Mental Illness and Addictions.

    Science.gov (United States)

    Hensel, Jennifer M; Taylor, Valerie H; Fung, Kinwah; Yang, Rebecca; Vigod, Simone N

    2018-01-01

    The role of mental illness and addiction in acute care use for chronic medical conditions that are sensitive to ambulatory care management requires focussed attention. This study examines how mental illness or addiction affects risk for repeat hospitalization and/or emergency department use for ambulatory care-sensitive conditions (ACSCs) among high-cost users of medical care. A retrospective, population-based cohort study using data from Ontario, Canada. Among the top 10% of medical care users ranked by cost, we determined rates of any and repeat care use (hospitalizations and emergency department [ED] visits) between April 1, 2011, and March 31, 2012, for 14 consensus established ACSCs and compared them between those with and without diagnosed mental illness or addiction during the 2 years prior. Risk ratios were adjusted (aRR) for age, sex, residence, and income quintile. Among 314,936 high-cost users, 35.9% had a mental illness or addiction. Compared to those without, individuals with mental illness or addiction were more likely to have an ED visit or hospitalization for any ACSC (22.8% vs. 19.6%; aRR, 1.21; 95% confidence interval [CI], 1.20-1.23). They were also more likely to have repeat ED visits or hospitalizations for the same ACSC (6.2% vs. 4.4% of those without; aRR, 1.48; 95% CI, 1.44-1.53). These associations were stronger in stratifications by mental illness diagnostic subgroup, particularly for those with a major mental illness. The presence of mental illness and addiction among high-cost users of medical services may represent an unmet need for quality ambulatory and primary care.

  11. Social and economic well-being in the conditions of the urban space: the evolution of methodological approaches in the historical urban studies

    Directory of Open Access Journals (Sweden)

    Ageev Ilya

    2016-01-01

    Full Text Available A city as a type of a human settlement is characterized by high population density, welldeveloped infrastructure, comfortable living conditions. However, a city is a source of social problems due to high population density, limited resources and conflicts between indigenous population and newcomers. The article analyzes the development of research about the city, provides an assessment of the scope of the historical urban studies in the development of solutions to contemporary problems of urban space. Methodological resource of historical urban studies allows fully exploring the city as a set of historically interconnected spaces and social processes. The analysis of the problem field of historical urban studies at various stages of its formation allowed tracing the evolution of ideas about the city as an object of scientific knowledge, to identify future prospects of research on conditions of Russian urban development, to improve the comfort of living in them.

  12. Hygrothermal optimisation of museum storage spaces

    DEFF Research Database (Denmark)

    Janssen, Hans; Christensen, Jørgen Erik

    2013-01-01

    Despite the large economic and ecologic costs, museum storage spaces are often equipped with extensive air conditioning, to provide the desired stable interior climate. The new “passive conditioning” paradigm aims at resolving these costs: a high-hygrothermal-inertia building with a high-hygrothe......Despite the large economic and ecologic costs, museum storage spaces are often equipped with extensive air conditioning, to provide the desired stable interior climate. The new “passive conditioning” paradigm aims at resolving these costs: a high-hygrothermal-inertia building with a high...... and ecologic cost of conditioning, the paper finally assesses “concentrated dehumidification”: dehumidification during a part of the day only, while leaving the humidity free-running during the rest of the day. It is established that the hygric inertia of the interior air, building walls and stored objects...

  13. Building America Case Study: Effect of Ducted HPWH on Space Conditioning and Water Heating Energy Use - Central Florida Lab Home, Cocoa, Florida

    Energy Technology Data Exchange (ETDEWEB)

    C. Colon, E. Martin, and D. Parker

    2017-04-01

    The purpose of this research is to investigate the impact of ducted heat pump water heaters (HPWH's) on space conditioning and water heating energy use in residential applications. Two identical HPWH's, each of 60 gallon capacity were tested side by side at the Flexible Residential Test facility (FRTF) laboratories of the Florida Solar Energy Center (FSEC) campus in Cocoa, Florida. The water heating experiments were run in each test house from July 2014 until February 2015.

  14. Simplified Space Conditioning in Low-Load Homes: Results from Pittsburgh, Pennsylvania, New Construction Unoccupied Test House

    Energy Technology Data Exchange (ETDEWEB)

    Poerschke, A.; Stecher, D.

    2014-06-01

    Field testing was performed in a new construction unoccupied test house in Pittsburgh, Pennsylvania. Four air-based heating, ventilation, and air conditioning distribution systems--a typical airflow ducted system to the bedrooms, a low airflow ducted system to the bedrooms, a system with transfer fans to the bedrooms, and a system with no ductwork to the bedrooms--were evaluated during heating, cooling, and midseason conditions. The relative ability of each system was assessed with respect to relevant Air Conditioning Contractors of America and ASHRAE standards for house temperature uniformity and stability, respectively.

  15. Simplified Space Conditioning in Low-Load Homes: Results from Pittsburgh, Pennsylvania, New Construction Unoccupied Test House

    Energy Technology Data Exchange (ETDEWEB)

    Poerschke, Andrew [IBACOS, Inc., Pittsburgh, PA (United States); Stecher, Dave [IBACOS, Inc., Pittsburgh, PA (United States)

    2014-06-01

    Field testing was performed in a new construction unoccupied test house in Pittsburgh, PA. Four air-based heating, ventilation, and air conditioning distribution systems—a typical airflow ducted system to the bedrooms, a low airflow ducted system to the bedrooms, a system with transfer fans to the bedrooms, and a system with no ductwork to the bedrooms—were evaluated during heating, cooling, and midseason conditions. The relative ability of each system was assessed with respect to relevant Air Conditioning Contractors of America and ASHRAE standards for house temperature uniformity and stability, respectively.

  16. Boundary-value problems with integral conditions for a system of Lame equations in the space of almost periodic functions

    Directory of Open Access Journals (Sweden)

    Volodymyr S. Il'kiv

    2016-11-01

    Full Text Available We study a problem with integral boundary conditions in the time coordinate for a system of Lame equations of dynamic elasticity theory of an arbitrary dimension. We find necessary and sufficient conditions for the existence and uniqueness of solution in the class of almost periodic functions in the spatial variables. To solve the problem of small denominators arising while constructing solutions, we use the metric approach.

  17. Communication: Recovering the flat-plane condition in electronic structure theory at semi-local DFT cost

    Science.gov (United States)

    Bajaj, Akash; Janet, Jon Paul; Kulik, Heather J.

    2017-11-01

    The flat-plane condition is the union of two exact constraints in electronic structure theory: (i) energetic piecewise linearity with fractional electron removal or addition and (ii) invariant energetics with change in electron spin in a half filled orbital. Semi-local density functional theory (DFT) fails to recover the flat plane, exhibiting convex fractional charge errors (FCE) and concave fractional spin errors (FSE) that are related to delocalization and static correlation errors. We previously showed that DFT+U eliminates FCE but now demonstrate that, like other widely employed corrections (i.e., Hartree-Fock exchange), it worsens FSE. To find an alternative strategy, we examine the shape of semi-local DFT deviations from the exact flat plane and we find this shape to be remarkably consistent across ions and molecules. We introduce the judiciously modified DFT (jmDFT) approach, wherein corrections are constructed from few-parameter, low-order functional forms that fit the shape of semi-local DFT errors. We select one such physically intuitive form and incorporate it self-consistently to correct semi-local DFT. We demonstrate on model systems that jmDFT represents the first easy-to-implement, no-overhead approach to recovering the flat plane from semi-local DFT.

  18. Design of the Experimental Exposure Conditions to Simulate Ionizing Radiation Effects on Candidate Replacement Materials for the Hubble Space Telescope

    Science.gov (United States)

    Smith, L. Montgomery

    1998-09-01

    In this effort, experimental exposure times for monoenergetic electrons and protons were determined to simulate the space radiation environment effects on Teflon components of the Hubble Space Telescope. Although the energy range of the available laboratory particle accelerators was limited, optimal exposure times for 50 keV, 220 keV, 350 keV, and 500 KeV electrons were calculated that produced a dose-versus-depth profile that approximated the full spectrum profile, and were realizable with existing equipment. For the case of proton exposure, the limited energy range of the laboratory accelerator restricted simulation of the dose to a depth of .5 mil. Also, while optimal exposure times were found for 200 keV, 500 keV and 700 keV protons that simulated the full spectrum dose-versus-depth profile to this depth, they were of such short duration that the existing laboratory could not be controlled to within the required accuracy. In addition to the obvious experimental issues, other areas exist in which the analytical work could be advanced. Improved computer codes for the dose prediction- along with improved methodology for data input and output- would accelerate and make more accurate the calculational aspects. This is particularly true in the case of proton fluxes where a paucity of available predictive software appears to exist. The dated nature of many of the existing Monte Carlo particle/radiation transport codes raises the issue as to whether existing codes are sufficient for this type of analysis. Other areas that would result in greater fidelity of laboratory exposure effects to the space environment is the use of a larger number of monoenergetic particle fluxes and improved optimization algorithms to determine the weighting values.

  19. Body Condition Scores and Evaluation of Feeding Habits of Dogs and Cats at a Low Cost Veterinary Clinic and a General Practice

    Directory of Open Access Journals (Sweden)

    Stephanie A. Sapowicz

    2016-01-01

    Full Text Available This study assessed body condition scores (BCS and feeding habits for dogs and cats. Eighty-six cats and 229 dogs (and their owners were enrolled from 2 clinics: a low cost clinic (n=149 and a general practice (n=166. BCS and body weight were recorded. Owners completed a survey which included animal age, sex, and breed; owner demographics; and feeding practices (e.g., diet, rationale for feeding practices. Owners from the low cost clinic had a significantly lower income (P<0.001 and education (P<0.001 compared to those from the general practice. Animals from the low cost clinic were younger (P<0.001 and dogs were less likely to be neutered (P<0.001. Overweight prevalence was 55% overall (P=0.083, with a significantly higher prevalence in the general practice for cats (44% versus 66%; P=0.046, but not for dogs (58% versus 53%; P=0.230. Multivariate analysis showed that only neuter status was significantly associated with BCS (P=0.004. Veterinarians were the most common source of nutritional information, though lack of accurate nutrition knowledge was common among all participants. These findings support the need for enhanced communication about optimal BCS and nutrition regardless of socioeconomic status.

  20. The metabolic costs of improving ethanol yield by reducing glycerol formation capacity under anaerobic conditions in Saccharomyces cerevisiae.

    Science.gov (United States)

    Pagliardini, Julien; Hubmann, Georg; Alfenore, Sandrine; Nevoigt, Elke; Bideaux, Carine; Guillouet, Stephane E

    2013-03-28

    Finely regulating the carbon flux through the glycerol pathway by regulating the expression of the rate controlling enzyme, glycerol-3-phosphate dehydrogenase (GPDH), has been a promising approach to redirect carbon from glycerol to ethanol and thereby increasing the ethanol yield in ethanol production. Here, strains engineered in the promoter of GPD1 and deleted in GPD2 were used to investigate the possibility of reducing glycerol production of Saccharomyces cerevisiae without jeopardising its ability to cope with process stress during ethanol production. For this purpose, the mutant strains TEFmut7 and TEFmut2 with different GPD1 residual expression were studied in Very High Ethanol Performance (VHEP) fed-batch process under anaerobic conditions. Both strains showed a drastic reduction of the glycerol yield by 44 and 61% while the ethanol yield improved by 2 and 7% respectively. TEFmut2 strain showing the highest ethanol yield was accompanied by a 28% reduction of the biomass yield. The modulation of the glycerol formation led to profound redox and energetic changes resulting in a reduction of the ATP yield (YATP) and a modulation of the production of organic acids (acetate, pyruvate and succinate). Those metabolic rearrangements resulted in a loss of ethanol and stress tolerance of the mutants, contrarily to what was previously observed under aerobiosis. This work demonstrates the potential of fine-tuned pathway engineering, particularly when a compromise has to be found between high product yield on one hand and acceptable growth, productivity and stress resistance on the other hand. Previous study showed that, contrarily to anaerobiosis, the resulting gain in ethanol yield was accompanied with no loss of ethanol tolerance under aerobiosis. Moreover those mutants were still able to produce up to 90 gl-1 ethanol in an anaerobic SSF process. Fine tuning metabolic strategy may then open encouraging possibilities for further developing robust strains with improved

  1. Economic viability of Stratified Medicine concepts: An investor perspective on drivers and conditions that favour using Stratified Medicine approaches in a cost-contained healthcare environment.

    Science.gov (United States)

    Fugel, Hans-Joerg; Nuijten, Mark; Postma, Maarten

    2016-12-25

    Stratified Medicine (SM) is becoming a natural result of advances in biomedical science and a promising path for the innovation-based biopharmaceutical industry to create new investment opportunities. While the use of biomarkers to improve R&D efficiency and productivity is very much acknowledged by industry, much work remains to be done to understand the drivers and conditions that favour using a stratified approach to create economically viable products and to justify the investment in SM interventions as a stratification option. In this paper we apply a decision analytical methodology to address the economic attractiveness of different SM development options in a cost-contained healthcare environment. For this purpose, a hypothetical business case in the oncology market has been developed considering four feasible development scenarios. The article outlines the effects of development time and time to peak sales as key economic value drivers influencing profitability of SM interventions under specific conditions. If regulatory and reimbursement challenges can be solved, decreasing development time and enhancing early market penetration would most directly improve the economic attractiveness of SM interventions. Appropriate tailoring of highly differentiated patient subgroups is the prerequisite to leverage potential efficiency gains in the R&D process. Also, offering a better targeted and hence ultimately more cost-effective therapy at reimbursable prices will facilitate time to market access and allow increasing market share gains within the targeted populations. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Uptake, outcomes, and costs of antenatal, well-baby, and prevention of mother-to-child transmission of HIV services under routine care conditions in Zambia.

    Directory of Open Access Journals (Sweden)

    Callie A Scott

    Full Text Available BACKGROUND: Zambia adopted Option A for prevention of mother-to-child transmission of HIV (PMTCT in 2010 and announced a move to Option B+ in 2013. We evaluated the uptake, outcomes, and costs of antenatal, well-baby, and PMTCT services under routine care conditions in Zambia after the adoption of Option A. METHODS: We enrolled 99 HIV-infected/HIV-exposed (index mother/baby pairs with a first antenatal visit in April-September 2011 at four study sites and 99 HIV-uninfected/HIV-unexposed (comparison mother/baby pairs matched on site, gestational age, and calendar month at first visit. Data on patient outcomes and resources utilized from the first antenatal visit through six months postpartum were extracted from site registers. Costs in 2011 USD were estimated from the provider's perspective. RESULTS: Index mothers presented for antenatal care at a mean 23.6 weeks gestation; 55% were considered to have initiated triple-drug antiretroviral therapy (ART based on information recorded in site registers. Six months postpartum, 62% of index and 30% of comparison mother/baby pairs were retained in care; 67% of index babies retained had an unknown HIV status. Comparison and index mother/baby pairs utilized fewer resources than under fully guideline-concordant care; index babies utilized more well-baby resources than comparison babies. The average cost per comparison pair retained in care six months postpartum was $52 for antenatal and well-baby services. The average cost per index pair retained was $88 for antenatal, well-baby, and PMTCT services and increased to $185 when costs of triple-drug ART services were included. CONCLUSIONS: HIV-infected mothers present to care late in pregnancy and many are lost to follow up by six months postpartum. HIV-exposed babies are more likely to remain in care and receive non-HIV, well-baby care than HIV-unexposed babies. Improving retention in care, guideline concordance, and moving to Option B+ will result in

  3. Cell genetic processes under space flight conditions: Analysis of two-factor crosses between spore color mutants of Sordaria macrospora. Final report

    International Nuclear Information System (INIS)

    Hock, B.; Hahn, A.

    2001-01-01

    The purpose of the FUNGUS experiment on S/MM05 was to examine the effects of space flight conditions on the hereditary transmission of the spore color genes. The controls consisted of one further experiment in space with a centrifuge and 1 x g acceleration, and a gravitational reference experiment. A statistical analysis revealed no significant differences attributable to the absence of gravitational effects. A significant increase however was observed in the recombination frequencies, due to the fraction of HZE particles in the cosmic radiation. Gravitational reference experiments showed a dose-dependent effect of heavy-ion particle radiation on the post-reduction frequency and thus on the calculated distances between the genes, higher radiation doses increasing the post-reduction frequency. It was possible to derive dose-response curves for comparison with X-radiation and determination of the RBE of the heavy ion radiation with respect to the calculated distances between the genes 1u and r2. The mycelium of the fungi of the space flight experiment was examined for DNA strand breaks at the molecular level by means of a single cell gel electrophoresis assay. No genetic damage could be detected in the specimens of the experiment in space. Attempts at DNA repair in S. macrospora reveal that most of the damage is healed within a few hours. It was possible to determine the maximum doses of ionizing and non-ionizing radiation up to which DNA repair is possible. (orig./CB) [de

  4. Elements of a pragmatic approach for dealing with bias and uncertainty in experiments through predictions : experiment design and data conditioning; %22real space%22 model validation and conditioning; hierarchical modeling and extrapolative prediction.

    Energy Technology Data Exchange (ETDEWEB)

    Romero, Vicente Jose

    2011-11-01

    This report explores some important considerations in devising a practical and consistent framework and methodology for utilizing experiments and experimental data to support modeling and prediction. A pragmatic and versatile 'Real Space' approach is outlined for confronting experimental and modeling bias and uncertainty to mitigate risk in modeling and prediction. The elements of experiment design and data analysis, data conditioning, model conditioning, model validation, hierarchical modeling, and extrapolative prediction under uncertainty are examined. An appreciation can be gained for the constraints and difficulties at play in devising a viable end-to-end methodology. Rationale is given for the various choices underlying the Real Space end-to-end approach. The approach adopts and refines some elements and constructs from the literature and adds pivotal new elements and constructs. Crucially, the approach reflects a pragmatism and versatility derived from working many industrial-scale problems involving complex physics and constitutive models, steady-state and time-varying nonlinear behavior and boundary conditions, and various types of uncertainty in experiments and models. The framework benefits from a broad exposure to integrated experimental and modeling activities in the areas of heat transfer, solid and structural mechanics, irradiated electronics, and combustion in fluids and solids.

  5. Experimental and theoretical investigations of Cs-Ba vapor tacitron inverter for power conditioning in space power systems

    International Nuclear Information System (INIS)

    El-Genk, M.; Murray, C.; Wernsman, B.

    1993-01-01

    The operation characteristics of the Cs-Ba tacitron as a switch are investigated experimentally in three modes: (a) breakdown mode, (b) I-V mode, and (c) current modulation mode. The switching frequency, grid potentials for ignition and extinguishing of discharge, and the Cs pressure and emission conditions (Ba pressure and emitter temperature) for stable current modulation are determined. The experimental data is also used to determine the off-time required for successful ignition, and the effects of the aforementioned operation parameters on the ignition duty cycle threshold for stable modulation. Operation parameters measured include switching frequency up to 20 kHz, hold-off voltage up to 180 V, current densities in excess of 15 A/cm 2 , switch power density of 1 kW/cm 2 . and a switching efficiency in excess of 90% at collector C: realer than 30 V. The voltage drop strongly depends on the Cs pressure and to a lesser extent on the emission conditions. Increasing the Cs pressure and/or the emission current lowers the voltage drop, however, for the same initial Cs pressure and emission conditions, the voltage drop in the I-V mode is usually lower than that during current modulation. As long as the discharge current is kept lower that the.emission current, the voltage drop during stable current modulation could be as low as 3 V

  6. Revaluation of the concept of the human condition and the common heritage of mankind: Keys to the social benefits of space technology

    Science.gov (United States)

    Cocca, Aldo Armando

    Men may do many things, but they must never forget the human condition in any act or relation with a fellow human being. Space Law has vindicated the supreme value of man as a legal subject par excellence. The dignity of the human being is a value that rates above any scientific or technological advance. A benefit, by definition and derivation, is anything contributing to an improvement in a condition. Social benefits pertain only to human beings, who are their sole beneficiaries. Developing countries are young nations that through their international relations may, and indeed must, realize the benefits of space technology. The principle of the "common heritage of Mankind" was created to satisfy the aspirations of all peoples and to meet the needs of both industrialized and developing countries. Only a groundless fear and lack of vision of the future can induce governments to delay its implementation. We must not forget that the concept was transformed into a principle of international positive law by the unanimous decision of the international community, which enshrined it in the Moon Agreement. The social and individual responsibility of the scientist is becoming even more clearly defined, and scientists play an important role in the conduct of nations. Through education, including education in the humanities and a graduation pledge, the scientist has embarked on the road leading to an active presence in society, facing his responsibility. Inter-generational equity contributes to strengthening the concept of the human condition and the legal principle of the common heritage of mankind.

  7. Reconstruction of Oryza sativa indica Genome Scale Metabolic Model and Its Responses to Varying RuBisCO Activity, Light Intensity, and Enzymatic Cost Conditions

    Directory of Open Access Journals (Sweden)

    Ankita Chatterjee

    2017-11-01

    Full Text Available To combat decrease in rice productivity under different stresses, an understanding of rice metabolism is needed. Though there are different genome scale metabolic models (GSMs of Oryza sativa japonica, no GSM with gene-protein-reaction association exist for Oryza sativa indica. Here, we report a GSM, OSI1136 of O.s. indica, which includes 3602 genes and 1136 metabolic reactions and transporters distributed across the cytosol, mitochondrion, peroxisome, and chloroplast compartments. Flux balance analysis of the model showed that for varying RuBisCO activity (Vc/Vo (i the activity of the chloroplastic malate valve increases to transport reducing equivalents out of the chloroplast under increased photorespiratory conditions and (ii glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase can act as source of cytosolic ATP under decreased photorespiration. Under increasing light conditions we observed metabolic flexibility, involving photorespiration, chloroplastic triose phosphate and the dicarboxylate transporters of the chloroplast and mitochondrion for redox and ATP exchanges across the intracellular compartments. Simulations under different enzymatic cost conditions revealed (i participation of peroxisomal glutathione-ascorbate cycle in photorespiratory H2O2 metabolism (ii different modes of the chloroplastic triose phosphate transporters and malate valve, and (iii two possible modes of chloroplastic Glu–Gln transporter which were related with the activity of chloroplastic and cytosolic isoforms of glutamine synthetase. Altogether, our results provide new insights into plant metabolism.

  8. Performance Evaluation of Target Detection with a Near-Space Vehicle-Borne Radar in Blackout Condition.

    Science.gov (United States)

    Li, Yanpeng; Li, Xiang; Wang, Hongqiang; Deng, Bin; Qin, Yuliang

    2016-01-06

    Radar is a very important sensor in surveillance applications. Near-space vehicle-borne radar (NSVBR) is a novel installation of a radar system, which offers many benefits, like being highly suited to the remote sensing of extremely large areas, having a rapidly deployable capability and having low vulnerability to electronic countermeasures. Unfortunately, a target detection challenge arises because of complicated scenarios, such as nuclear blackout, rain attenuation, etc. In these cases, extra care is needed to evaluate the detection performance in blackout situations, since this a classical problem along with the application of an NSVBR. However, the existing evaluation measures are the probability of detection and the receiver operating curve (ROC), which cannot offer detailed information in such a complicated application. This work focuses on such requirements. We first investigate the effect of blackout on an electromagnetic wave. Performance evaluation indexes are then built: three evaluation indexes on the detection capability and two evaluation indexes on the robustness of the detection process. Simulation results show that the proposed measure will offer information on the detailed performance of detection. These measures are therefore very useful in detecting the target of interest in a remote sensing system and are helpful for both the NSVBR designers and users.

  9. Estimated characteristics modification of silicon detectors due to their use at the LHC-accelerator and in AMS space conditions

    International Nuclear Information System (INIS)

    Lazanu, I.; Lazanu, S.

    2003-01-01

    In this talk, the phenomenological model developed by the authors in previous papers has been used to evaluate the degradation induced in high resistivity silicon detectors by pion and proton irradiation at the future accelerator facilities or by cosmic protons considering the continuous irradiation for ten years of work. The equations governing the degradation of the lattice are explicitly considered. The damage has been analysed at the microscopic level (defects production and their evolution toward equilibrium) and at the macroscopic level (only the changes in the leakage current of the p-n junction was considered). The rates of production of primary defects, as well as their evolution toward equilibrium have been evaluated considering explicitly irradiation field of the specified applications, by the type of the projectile particle and its energy. The influence of these defects on the leakage current density has been compared with experimental data from the literature, and predictions for the LHC radiation fields, as well as for space missions in the near Earth orbits have been done, in the frame of the Schokley-Read-Hall model. (authors)

  10. Demonstration of intradyne BPSK optical free-space transmission in representative atmospheric turbulence conditions for geostationary uplink channel.

    Science.gov (United States)

    Surof, Janis; Poliak, Juraj; Calvo, Ramon Mata

    2017-06-01

    Binary phase-shift keying optical transmission in the C-band with coherent intradyne reception is demonstrated over a long-range (10.45 km) link through the atmosphere. The link emulates representative channel conditions for geostationary optical feeder uplinks in satellite communications. The digital signal processing used in recovering the transmitted data and the performed measurements are described. Finally, the bit error rate results for 10 Gbit/s, 20 Gbit/s, and 30 Gbit/s of the outdoor experiments are presented and compared with back-to-back measurements and theory.

  11. Simulation from endpoint-conditioned, continuous-time Markov chains on a finite state space, with applications to molecular evolution

    DEFF Research Database (Denmark)

    Hobolth, Asger; Stone, Eric

    2009-01-01

    computational finance to human genetics and genomics. A common theme among these diverse applications is the need to simulate sample paths of a CTMC conditional on realized data that is discretely observed. Here we present a general solution to this sampling problem when the CTMC is defined on a discrete....... In doing so, we show that no method dominates the others across all model specifications, and we give explicit proof of which method prevails for any given Q, T, and endpoints. Finally, we introduce and compare three applications of CTMCs to demonstrate the pitfalls of choosing an inefficient sampler....

  12. Studies of social group dynamics under isolated conditions. Objective summary of the literature as it relates to potential problems of long duration space flight

    Science.gov (United States)

    Vinograd, S. P.

    1974-01-01

    Scientific literature which deals with the study of human behavior and crew interaction in situations simulating long term space flight is summarized and organized. A bibliography of all the pertinent U.S. literature available is included, along with definitions of the behavioral characteristics terms employed. The summarized studies are analyzed according to behavioral factors and environmental conditions. The analysis consist of two matrices. (1) The matrix of factors studied correlates each research study area and individual study with the behavioral factors that were investigated in the study. (2) The matrix of conclusions identifies those studies whose investigators appeared to draw specific conclusions concerning questions of importance to NASA.

  13. NASA's Advanced Solar Sail Propulsion System for Low-Cost Deep Space Exploration and Science Missions that Use High Performance Rollable Composite Booms

    Science.gov (United States)

    Fernandez, Juan M.; Rose, Geoffrey K.; Younger, Casey J.; Dean, Gregory D.; Warren, Jerry E.; Stohlman, Olive R.; Wilkie, W. Keats

    2017-01-01

    Several low-cost solar sail technology demonstrator missions are under development in the United States. However, the mass saving derived benefits that composites can offer to such a mass critical spacecraft architecture have not been realized yet. This is due to the lack of suitable composite booms that can fit inside CubeSat platforms and ultimately be readily scalable to much larger sizes, where they can fully optimize their use. With this aim, a new effort focused at developing scalable rollable composite booms for solar sails and other deployable structures has begun. Seven meter booms used to deploy a 90 m2 class solar sail that can fit inside a 6U CubeSat have already been developed. The NASA road map to low-cost solar sail capability demonstration envisioned, consists of increasing the size of these composite booms to enable sailcrafts with a reflective area of up to 2000 m2 housed aboard small satellite platforms. This paper presents a solar sail system initially conceived to serve as a risk reduction alternative to Near Earth Asteroid (NEA) Scout's baseline design but that has recently been slightly redesigned and proposed for follow-on missions. The features of the booms and various deployment mechanisms for the booms and sail, as well as ground support equipment used during testing, are introduced. The results of structural analyses predict the performance of the system under microgravity conditions. Finally, the results of the functional and environmental testing campaign carried out are shown.

  14. Optimal numbers of matings: the conditional balance between benefits and costs of mating for females of a nuptial gift-giving spider.

    Science.gov (United States)

    Toft, S; Albo, M J

    2015-02-01

    In species where females gain a nutritious nuptial gift during mating, the balance between benefits and costs of mating may depend on access to food. This means that there is not one optimal number of matings for the female but a range of optimal mating numbers. With increasing food availability, the optimal number of matings for a female should vary from the number necessary only for fertilization of her eggs to the number needed also for producing these eggs. In three experimental series, the average number of matings for females of the nuptial gift-giving spider Pisaura mirabilis before egg sac construction varied from 2 to 16 with food-limited females generally accepting more matings than well-fed females. Minimal level of optimal mating number for females at satiation feeding conditions was predicted to be 2-3; in an experimental test, the median number was 2 (range 0-4). Multiple mating gave benefits in terms of increased fecundity and increased egg hatching success up to the third mating, and it had costs in terms of reduced fecundity, reduced egg hatching success after the third mating, and lower offspring size. The level of polyandry seems to vary with the female optimum, regulated by a satiation-dependent resistance to mating, potentially leaving satiated females in lifelong virginity. © 2015 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2015 European Society For Evolutionary Biology.

  15. Numerical simulation of the effect of wind removing the corona space charge over grounded structures under thunderstorm conditions

    DEFF Research Database (Denmark)

    Vogel, Stephan; Lopez, Javier; Holbøll, Joachim

    2015-01-01

    agrounded object under thunderstorm conditions. The electric fieldcreated by the charge distribution in the thundercloud above theobject, which is in first place enhanced by its geometry, leadsto the generation and secondly upward propagation of chargefrom the object. Recent investigations underline......Different types of tall structures are severely exposed to lightning discharges, including power lines, communicationtowers, buildings and wind turbines all over the world. Thepresent paper focuses on the numerical modelling and simulationof the effect of wind on the electric field developed over...... quantifies thedifference between static towers and rotating wind turbines whichare influenced by different resultant wind velocities. The voltagedistribution and ion drift velocities in the vicinity of the groundedstructures are illustrated. The results show a higher voltagegradient at the side of the object...

  16. Hygrothermal conditions in cold, north facing attic spaces under the eaves with vapour-open roofing underlay in a cool, temperate climate

    DEFF Research Database (Denmark)

    Bjarløv, Søren Peter; Johnston, C.J.; Hansen, M.H.

    2016-01-01

    compliance with the current Danish Building Regulations (BR10) for airtightness (moisture levels in attics with vapour-open roofing underlays. North facing cold attic spaces under the eaves constitute a worst case scenario. Following best...... to allow an influx of 3.3 l/s of conditioned indoor air 20 °C and 60% RH at a pressure difference of 50 Pa) and ventilation (singled-sided, passive ventilation) contained more moisture and had significantly higher levels of mould growth than the non-ventilated attics. Under the same physical conditions...... the ‘pressure equalized’ attic rooms were found to have moisture levels in between those observed in the ventilated and non-ventilated attic rooms. Likewise, the observed levels of mould growth were in between those observed in the cases of the ventilated and non-ventilated attic rooms. Attics with reduced...

  17. Solar Air Collectors for Space Heating and Ventilation Applications—Performance and Case Studies under Romanian Climatic Conditions

    Directory of Open Access Journals (Sweden)

    Sanda Budea

    2014-06-01

    Full Text Available Solar air collectors have various applications: on the one hand, they can be used for air heating in cold seasons; on the other hand they can be used in summer to evacuate the warm and polluted air from residential, offices, industrial, and commercial buildings. The paper presents experimental results of a solar collector air, under the climatic conditions of the Southeastern Europe. The relationships between the direct solar irradiation, the resulting heat flow, the air velocity at the outlet, the air flow rate, the nominal regime of the collector and the efficiency of conversion of solar energy into thermal energy are all highlighted. Thus, it was shown that after a maximum 50 min, solar air collectors, with baffles and double air passage can reach over 50% efficiency for solar irradiation of 900–1000 W/m2. The article also presents a mathematical model and the results of a computational program that allows sizing solar collectors for the transfer of air, with the purpose of improving the natural ventilation of buildings. The article is completed with case studies, sizing the area to be covered with solar collectors, to ensure ventilation of a house with two floors or for an office building. In addition, the ACH (air change per hour coefficient was calculated and compared.

  18. Least momentum space frustration as a condition for a ‘high Tc sweet spot’ in iron-based superconductors

    International Nuclear Information System (INIS)

    Usui, Hidetomo; Suzuki, Katsuhiro; Kuroki, Kazuhiko

    2012-01-01

    In the present paper, we describe how the band structure and the Fermi surface of iron-based superconductors vary as the Fe–As–Fe bond angle changes. We discuss how these Fermi surface configurations affect the superconductivity mediated by spin fluctuations, and show that, in several situations, frustration in the sign of the gap function arises due to the repulsive pairing interactions that requires a sign change of the order parameter. Such a frustration can result in nodes or very small gaps, and generally works destructively against superconductivity. Conversely, we propose that the optimal condition for superconductivity is realized for the Fermi surface configuration that gives the least frustration while maximizing the Fermi surface multiplicity. This is realized when there are three hole Fermi surfaces, where two of them have d XZ/YZ orbital character and one has d X 2 −Y 2 for all k z in the three-dimensional Brillouin zone. Looking at the band structures of various iron-based superconductors, the occurrence of such a ‘sweet spot’ situation is limited to a narrow window. (paper)

  19. Exergy analysis of a two-stage ground source heat pump with a vertical bore for residential space conditioning under simulated occupancy

    International Nuclear Information System (INIS)

    Ally, Moonis R.; Munk, Jeffrey D.; Baxter, Van D.; Gehl, Anthony C.

    2015-01-01

    Highlights: • Exergy and energy analysis of a vertical-bore ground source heat pump over a 12-month period is presented. • The ground provided more than 75% of the heating energy. • Performance metrics are presented. • Sources of systemic inefficiency are identified and prioritized using Exergy analysis. • Understanding performance metrics is vital for judicial use of renewable energy. - Abstract: This twelve-month field study analyzes the performance of a 7.56 W (2.16-ton) water-to-air-ground source heat pump (WA-GSHP) to satisfy domestic space conditioning loads in a 253 m 2 house in a mixed-humid climate in the United States. The practical feasibility of using the ground as a source of renewable energy is clearly demonstrated. Better than 75% of the energy needed for space heating was extracted from the ground. The average monthly electricity consumption for space conditioning was only 40 kW h at summer and winter thermostat set points of 24.4 °C and 21.7 °C, respectively. The WA-GSHP shared the same 94.5 m vertical bore ground loop with a separate water-to-water ground-source heat pump (WW-GSHP) for meeting domestic hot water needs in the same house. Sources of systemic irreversibility, the main cause of lost work, are identified using Exergy and energy analysis. Quantifying the sources of Exergy and energy losses is essential for further systemic improvements. The research findings suggest that the WA-GSHPs are a practical and viable technology to reduce primary energy consumption and greenhouse gas emissions under the IECC 2012 Standard, as well as the European Union (EU) 2020 targets of using renewable energy resources

  20. Reducing cell-to-cell spacing for large-format lithium ion battery modules with aluminum or PCM heat sinks under failure conditions

    International Nuclear Information System (INIS)

    Coleman, Brittany; Ostanek, Jason; Heinzel, John

    2016-01-01

    Highlights: • Finite element analysis to evaluate heat sinks for large format li-ion batteries. • Solid metal heat sink and composite heat sink (metal filler and wax). • Transient simulations show response from rest to steady-state with normal load. • Transient simulations of two different failure modes were considered. • Significance of spacing, material properties, interface quality, and phase change. - Abstract: Thermal management is critical for large-scale, shipboard energy storage systems utilizing lithium-ion batteries. In recent years, there has been growing research in thermal management of lithium-ion battery modules. However, there is little information available on the minimum cell-to-cell spacing limits for indirect, liquid cooled modules when considering heat release during a single cell failure. For this purpose, a generic four-cell module was modeled using finite element analysis to determine the sensitivity of module temperatures to cell spacing. Additionally, the effects of different heat sink materials and interface qualities were investigated. Two materials were considered, a solid aluminum block and a metal/wax composite block. Simulations were run for three different transient load profiles. The first profile simulates sustained high rate operation where the system begins at rest and generates heat continuously until it reaches steady state. And, two failure mode simulations were conducted to investigate block performance during a slow and a fast exothermic reaction, respectively. Results indicate that composite materials can perform well under normal operation and provide some protection against single cell failure; although, for very compact designs, the amount of wax available to absorb heat is reduced and the effectiveness of the phase change material is diminished. The aluminum block design performed well under all conditions, and showed that heat generated during a failure is quickly dissipated to the coolant, even under the

  1. Frosting characteristics and heating performance of a direct-expansion solar-assisted heat pump for space heating under frosting conditions

    International Nuclear Information System (INIS)

    Huang, Wenzhu; Ji, Jie; Xu, Ning; Li, Guiqiang

    2016-01-01

    Highlights: • Frosting and heating performance of DX-SAHP under frosting conditions is investigated. • The conditions when DX-SAHP frosts are studied. • The frosting process is observed during 360 min of operating. • The effect of ambient temperature, relative humidity and solar irradiation is analyzed. - Abstract: Direct expansion solar-assisted heat pump system (DX-SAHP) is promising in energy saving applications, but the performance of DX-SAHP under frosting conditions is rarely reported in the published literatures. In this paper, a DX-SAHP system with bare solar collectors for space heating is designed and experimentally investigated in the enthalpy difference lab with a solar simulator. The system is tested under a range of frosting conditions, with the ambient temperatures from 7 °C to −3 °C, the relative humidities of 50%, 70% and 90% and the solar irradiances of 0 W/m"2, 100 W/m"2, 200 W/m"2 and 300 W/m"2. The conditions when the DX-SAHP system frosts are studied. Results show that solar irradiance as low as 100 W/m"2 can totally prevent frosting when the ambient temperature is above −3 °C and the relative humidity is 70%. Besides, the frosting process is observed to be slower than that of fin-and-tube heat exchangers. The evaporator is not seriously frosted and the system performance is not significantly influenced after 360 min of continuous operating. Moreover the effects of ambient parameters, including the ambient temperature and the relative humidity, especially solar irradiation, on the system performance are studied and analyzed. Solar irradiation can effectively prevent or retard frosting, and also improve the heating performance of the DX-SAHP system. The DX-SAHP system is proved to be applicable under frosting conditions.

  2. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Alpine Space wind map - Modeling approach

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Remund, J. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents describes the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report discusses two modelling approaches investigated for use in the definition of a wind map for the alpine area. The method chosen and its application are discussed. The various sources of information for input to the model are listed and discussed.

  3. Acoustic mode coupling induced by shallow water nonlinear internal waves: sensitivity to environmental conditions and space-time scales of internal waves.

    Science.gov (United States)

    Colosi, John A

    2008-09-01

    While many results have been intuited from numerical simulation studies, the precise connections between shallow-water acoustic variability and the space-time scales of nonlinear internal waves (NLIWs) as well as the background environmental conditions have not been clearly established analytically. Two-dimensional coupled mode propagation through NLIWs is examined using a perturbation series solution in which each order n is associated with nth-order multiple scattering. Importantly, the perturbation solution gives resonance conditions that pick out specific NLIW scales that cause coupling, and seabed attenuation is demonstrated to broaden these resonances, fundamentally changing the coupling behavior at low frequency. Sound-speed inhomogeneities caused by internal solitary waves (ISWs) are primarily considered and the dependence of mode coupling on ISW amplitude, range width, depth structure, location relative to the source, and packet characteristics are delineated as a function of acoustic frequency. In addition, it is seen that significant energy transfer to modes with initially low or zero energy involves at least a second order scattering process. Under moderate scattering conditions, comparisons of first order, single scattering theoretical predictions to direct numerical simulation demonstrate the accuracy of the approach for acoustic frequencies upto 400 Hz and for single as well as multiple ISW wave packets.

  4. Space Commercialization

    Science.gov (United States)

    Martin, Gary L.

    2011-01-01

    A robust and competitive commercial space sector is vital to continued progress in space. The United States is committed to encouraging and facilitating the growth of a U.S. commercial space sector that supports U.S. needs, is globally competitive, and advances U.S. leadership in the generation of new markets and innovation-driven entrepreneurship. Energize competitive domestic industries to participate in global markets and advance the development of: satellite manufacturing; satellite-based services; space launch; terrestrial applications; and increased entrepreneurship. Purchase and use commercial space capabilities and services to the maximum practical extent Actively explore the use of inventive, nontraditional arrangements for acquiring commercial space goods and services to meet United States Government requirements, including measures such as public-private partnerships, . Refrain from conducting United States Government space activities that preclude, discourage, or compete with U.S. commercial space activities. Pursue potential opportunities for transferring routine, operational space functions to the commercial space sector where beneficial and cost-effective.

  5. The effect of pre-existing health conditions on the cost of recovery from road traffic injury: insights from data linkage of medicare and compensable injury claims in Victoria, Australia.

    Science.gov (United States)

    Hassani-Mahmooei, Behrooz; Berecki-Gisolf, Janneke; Hahn, Youjin; McClure, Roderick J

    2016-04-29

    Comorbidity is known to affect length of hospital stay and mortality after trauma but less is known about its impact on recovery beyond the immediate post-accident care period. The aim of this study was to investigate the role of pre-existing health conditions in the cost of recovery from road traffic injury using health service use records for 1 year before and after the injury. Individuals who claimed Transport Accident Commission (TAC) compensation for a non-catastrophic injury that occurred between 2010 and 2012 in Victoria, Australia and who provided consent for Pharmaceutical Benefits Scheme (PBS) and Medicare Benefits Schedule (MBS) linkage were included (n = 738) in the analysis. PBS and MBS records dating from 12 months prior to injury were provided by the Department of Human Services (Canberra, Australia). Pre-injury use of health service items and pharmaceuticals were considered to indicate pre-existing health condition. Bayesian Model Averaging techniques were used to identify the items that were most strongly correlated with recovery cost. Multivariate regression models were used to determine the impact of these items on the cost of injury recovery in terms of compensated ambulance, hospital, medical, and overall claim cost. Out of the 738 study participants, 688 used at least one medical item (total of 15,625 items) and 427 used at least one pharmaceutical item (total of 9846). The total health service cost of recovery was $10,115,714. The results show that while pre-existing conditions did not have any significant impact on the total cost of recovery, categorical costs were affected: e.g. on average, for every anaesthetic in the year before the accident, hospital cost of recovery increased by 24 % [95 % CI: 13, 36 %] and for each pathological test related to established diabetes, hospital cost increased by $10,407 [5466.78, 15346.28]. For medical costs, each anaesthetic led to $258 higher cost [174.16, 341.16] and every prescription of drugs

  6. Tomosynthesis can facilitate accurate measurement of joint space width under the condition of the oblique incidence of X-rays in patients with rheumatoid arthritis.

    Science.gov (United States)

    Ono, Yohei; Kashihara, Rina; Yasojima, Nobutoshi; Kasahara, Hideki; Shimizu, Yuka; Tamura, Kenichi; Tsutsumi, Kaori; Sutherland, Kenneth; Koike, Takao; Kamishima, Tamotsu

    2016-06-01

    Accurate evaluation of joint space width (JSW) is important in the assessment of rheumatoid arthritis (RA). In clinical radiography of bilateral hands, the oblique incidence of X-rays is unavoidable, which may cause perceptional or measurement error of JSW. The objective of this study was to examine whether tomosynthesis, a recently developed modality, can facilitate a more accurate evaluation of JSW than radiography under the condition of oblique incidence of X-rays. We investigated quantitative errors derived from the oblique incidence of X-rays by imaging phantoms simulating various finger joint spaces using radiographs and tomosynthesis images. We then compared the qualitative results of the modified total Sharp score of a total of 320 joints from 20 patients with RA between these modalities. A quantitative error was prominent when the location of the phantom was shifted along the JSW direction. Modified total Sharp scores of tomosynthesis images were significantly higher than those of radiography, that is to say JSW was regarded as narrower in tomosynthesis than in radiography when finger joints were located where the oblique incidence of X-rays is expected in the JSW direction. Tomosynthesis can facilitate accurate evaluation of JSW in finger joints of patients with RA, even with oblique incidence of X-rays. Accurate evaluation of JSW is necessary for the management of patients with RA. Through phantom and clinical studies, we demonstrate that tomosynthesis may achieve more accurate evaluation of JSW.

  7. The Second Space Race

    Science.gov (United States)

    Fawkes, S.

    This paper compares and contrasts the characteristics of the first space race, which ran from the late 1950s to the late 1990s, and the second space race that began with the successful space flight of SpaceShipOne in 2004. The first space race was between superpowers seeking to establish geo-political dominance in the Cold War. The second space race will be between competing companies seeking to establish low cost access to space for ordinary people. The first space race achieved its geo- political objectives but did not open up low cost access to space but rather restricted access to a select few, highly trained astronauts and cosmonauts. The second space race, driven by the size and growth of the travel and tourism industry, promises to open up access to space to millions of space tourists.

  8. Seasonal performance and energy costs of oil or gas-fired boilers and furnaces

    Energy Technology Data Exchange (ETDEWEB)

    Berlad, A.L.; Lin, H.C.; Batey, J.; Salzano, F.J.; Yu, W.S.; Hoppe, R.J.; Allen, T.

    1977-03-01

    The seasonal operating cost of a small oil or gas-fired boiler or furnace depends upon the intrinsic merits of the device itself, the appropriateness of its capacity and cycle characteristics to the imposed load conditions, the weather characteristics and heat loss characteristics of the building being heated, and the control philosophy employed. The current study provides the bases for comparing quantitatively the seasonal operating costs of various specific space heating and/or domestic hot water systems, as influenced by the device specifics and device interaction with the space conditioned system that it serves. The resulting formalism is applied to various space-heating systems. Quantitative cost comparisons are presented.

  9. The Space Industry

    National Research Council Canada - National Science Library

    Borrelli, Carmine; Buckon, Danielle; Cogossi, Bruce; Davidson, Cynthia; Ditzler-Smith, Cristie; Doddato, August; Gabrielson, Charles; Hubbard, Kenneth; Jacocks, Kent; Jircitano, Valerie

    2007-01-01

    .... To ensure these, U.S. policy should encourage more commercial activity in space, emphasize a more globally cooperative environment, change acquisition methods to emphasize cost control over performance at any cost...

  10. DC-bus voltage control of grid-connected voltage source converter by using space vector modulated direct power control under unbalanced network conditions

    DEFF Research Database (Denmark)

    Xiao, Lei; Huang, Shoudao; Lu, Kaiyuan

    2013-01-01

    Unbalanced grid voltage will cause large dc-bus voltage ripple and introduce high harmonic current components on the grid side. This will severely threaten the safety of the grid-connected voltage source converter (VSC) and consequently, affect the healthy operation condition of the load. In this......Unbalanced grid voltage will cause large dc-bus voltage ripple and introduce high harmonic current components on the grid side. This will severely threaten the safety of the grid-connected voltage source converter (VSC) and consequently, affect the healthy operation condition of the load....... In this study, a new proportional-integral-resonant (PI-RES) controller-based, space vector modulated direct power control topology is proposed to suppress the dc-bus voltage ripple and in the same time, controlling effectively the instantaneous power of the VSC. A special ac reactive power reference component...... is introduced in the controller, which is necessary in order to reduce the dc-bus voltage ripple and active power harmonics at the same time. The proposed control topology is implemented in the lab. Simulation and experimental results are provided to validate its performance and the analysis presented...

  11. An adaptive neuro fuzzy inference system controlled space cector pulse width modulation based HVDC light transmission system under AC fault conditions

    Science.gov (United States)

    Ajay Kumar, M.; Srikanth, N. V.

    2014-03-01

    In HVDC Light transmission systems, converter control is one of the major fields of present day research works. In this paper, fuzzy logic controller is utilized for controlling both the converters of the space vector pulse width modulation (SVPWM) based HVDC Light transmission systems. Due to its complexity in the rule base formation, an intelligent controller known as adaptive neuro fuzzy inference system (ANFIS) controller is also introduced in this paper. The proposed ANFIS controller changes the PI gains automatically for different operating conditions. A hybrid learning method which combines and exploits the best features of both the back propagation algorithm and least square estimation method is used to train the 5-layer ANFIS controller. The performance of the proposed ANFIS controller is compared and validated with the fuzzy logic controller and also with the fixed gain conventional PI controller. The simulations are carried out in the MATLAB/SIMULINK environment. The results reveal that the proposed ANFIS controller is reducing power fluctuations at both the converters. It also improves the dynamic performance of the test power system effectively when tested for various ac fault conditions.

  12. On birecurrent spaces

    International Nuclear Information System (INIS)

    Rahman, M.S.

    1991-10-01

    A birecurrent space is defined with its classification and studied with involvement of Einstein, conformally flat, conformally symmetric and conformally recurrent spaces. A necessary and sufficient condition that a birecurrent space be recurrent is found. (author). 6 refs

  13. Conformal Einstein spaces

    International Nuclear Information System (INIS)

    Kozameh, C.N.; Newman, E.T.; Tod, K.P.

    1985-01-01

    Conformal transformations in four-dimensional. In particular, a new set of two necessary and sufficient conditions for a space to be conformal to an Einstein space is presented. The first condition defines the class of spaces conformal to C spaces, whereas the last one (the vanishing of the Bach tensor) gives the particular subclass of C spaces which are conformally related to Einstein spaces. (author)

  14. Survival of spores of the UV-resistant Bacillus subtilis strain MW01 after exposure to low-earth orbit and simulated martian conditions: data from the space experiment ADAPT on EXPOSE-E.

    Science.gov (United States)

    Wassmann, Marko; Moeller, Ralf; Rabbow, Elke; Panitz, Corinna; Horneck, Gerda; Reitz, Günther; Douki, Thierry; Cadet, Jean; Stan-Lotter, Helga; Cockell, Charles S; Rettberg, Petra

    2012-05-01

    In the space experiment "Molecular adaptation strategies of microorganisms to different space and planetary UV climate conditions" (ADAPT), bacterial endospores of the highly UV-resistant Bacillus subtilis strain MW01 were exposed to low-Earth orbit (LEO) and simulated martian surface conditions for 559 days on board the European Space Agency's exposure facility EXPOSE-E, mounted outside the International Space Station. The survival of B. subtilis MW01 spores from both assays (LEO and simulated martian conditions) was determined by a colony-formation assay after retrieval. It was clearly shown that solar extraterrestrial UV radiation (λ≥110 nm) as well as the martian UV spectrum (λ≥200 nm) was the most deleterious factor applied; in some samples only a few spore survivors were recovered from B. subtilis MW01 spores exposed in monolayers. However, if shielded from solar irradiation, about 8% of MW01 spores survived in LEO conditions, and 100% survived in simulated martian conditions, compared to the laboratory controls. The results demonstrate the effect of shielding against the high inactivation potential of extraterrestrial solar UV radiation, which limits the chances of survival of even the highly UV-resistant strain of B. subtilis MW01 in the harsh environments of outer space and the martian surface.

  15. Postulated Role of Vasoactive Neuropeptide-Related Immunopathology of the Blood Brain Barrier and Virchow-Robin Spaces in the Aetiology of Neurological-Related Conditions

    Directory of Open Access Journals (Sweden)

    D. R. Staines

    2008-01-01

    Full Text Available Vasoactive neuropeptides (VNs such as pituitary adenylate cyclase-activating polypeptide (PACAP and vasoactive intestinal peptide (VIP have critical roles as neurotransmitters, vasodilators including perfusion and hypoxia regulators, as well as immune and nociception modulators. They have key roles in blood vessels in the central nervous system (CNS including maintaining functional integrity of the blood brain barrier (BBB and blood spinal barrier (BSB. VNs are potent activators of adenylate cyclase and thus also have a key role in cyclic AMP production affecting regulatory T cell and other immune functions. Virchow-Robin spaces (VRSs are perivascular compartments surrounding small vessels within the CNS and contain VNs. Autoimmunity of VNs or VN receptors may affect BBB and VRS function and, therefore, may contribute to the aetiology of neurological-related conditions including multiple sclerosis, Parkinson's disease, and amyotrophic lateral sclerosis. VN autoimmunity will likely affect CNS and immunological homeostasis. Various pharmacological and immunological treatments including phosphodiesterase inhibitors and plasmapheresis may be indicated.

  16. Long-Term Costs and Health Consequences of Issuing Shorter Duration Prescriptions for Patients with Chronic Health Conditions in the English NHS.

    Science.gov (United States)

    Martin, Adam; Payne, Rupert; Wilson, Edward Cf

    2018-06-01

    The National Health Service (NHS) in England spends over £9 billion on prescription medicines dispensed in primary care, of which over two-thirds is accounted for by repeat prescriptions. Recently, GPs in England have been urged to limit the duration of repeat prescriptions, where clinically appropriate, to 28 days to reduce wastage and hence contain costs. However, shorter prescriptions will increase transaction costs and thus may not be cost saving. Furthermore, there is evidence to suggest that shorter prescriptions are associated with lower adherence, which would be expected to lead to lower clinical benefit. The objective of this study is to estimate the cost-effectiveness of 3-month versus 28-day repeat prescriptions from the perspective of the NHS. We adapted three previously developed UK policy-relevant models, incorporating transaction (dispensing fees, prescriber time) and drug wastage costs associated with 3-month and 28-day prescriptions in three case studies: antihypertensive medications for prevention of cardiovascular events; drugs to improve glycaemic control in patients with type 2 diabetes; and treatments for depression. In all cases, 3-month prescriptions were associated with lower costs and higher QALYs than 28-day prescriptions. This is driven by assumptions that higher adherence leads to improved disease control, lower costs and improved QALYs. Longer repeat prescriptions may be cost-effective compared with shorter ones. However, the quality of the evidence base on which this modelling is based is poor. Any policy rollout should be within the context of a trial such as a stepped-wedge cluster design.

  17. Cost-Sharing Contracts for Energy Saving and Emissions Reduction of a Supply Chain under the Conditions of Government Subsidies and a Carbon Tax

    Directory of Open Access Journals (Sweden)

    Yi Yuyin

    2018-03-01

    Full Text Available To study the cooperation of upstream and downstream enterprises of a supply chain in energy saving and emissions reduction, we establish a Stackelberg game model. The retailer moves first to decide a cost-sharing contract, then the manufacturer determines the energy-saving level, carbon-emission level, and wholesale price successively. In the end, the retailer determines the retail price. As a regulation, the government provides subsidies for energy-saving products, while imposing a carbon tax on the carbon emitted. The results show that (1 both the energy-saving cost-sharing (ECS and the carbon emissions reduction cost-sharing (CCS contracts are not the dominant strategy of the two parties by which they can facilitate energy savings and emissions reductions; (2 compared with single cost-sharing contracts, the bivariate cost-sharing (BCS contract for energy saving and emissions reduction is superior, although it still cannot realise prefect coordination of the supply chain; (3 government subsidy and carbon tax policies can promote the cooperation of both the upstream and downstream enterprises of the supply chain—a subsidy policy can always drive energy saving and emissions reductions, while a carbon tax policy does not always exert positive effects, as it depends on the initial level of pollution and the level of carbon tax; and (4 the subsidy policy reduces the coordination efficiency of the supply chain, while the influences of carbon tax policy upon the coordination efficiency relies on the initial carbon-emission level.

  18. Service use and costs for people with long-term neurological conditions in the first year following discharge from in-patient neuro-rehabilitation: a longitudinal cohort study.

    Directory of Open Access Journals (Sweden)

    Diana Jackson

    Full Text Available BACKGROUND: Knowledge of the configuration and costs of community rehabilitation and support for people with long-term neurological conditions (LTNCs is needed to inform future service development and resource allocation. In a multicentre prospective cohort study evaluating community service delivery during the year post-discharge from in-patient neuro-rehabilitation, a key objective was to determine service use, costs, and predictors of these costs. METHODS: Patients consecutively admitted over one year to all nine London specialised (Level 1 in-patient neuro-rehabilitation units were recruited on discharge. They or their carers completed postal/web-based questionnaires at discharge and six and twelve months later, providing demographic data and measures of impairment, disability, service needs and provision. This paper describes health and social care service use, informal care and associated costs. Regression models using non-parametric boot-strapping identified predictors of costs over time. RESULTS: Overall, 152 patients provided consistent data. Mean formal service costs fell significantly from £13,290 (sd £19,369 during the first six months to £9,335 (sd £19,036 from six-twelve months, (t = 2.35, P<0.05, mainly due to declining health service use. At six months, informal care was received on average for 8.2 hours/day, mean cost £14,615 (sd 23,305, comprising 52% of overall care costs. By twelve months, it had increased to 8.8 hours per day, mean cost £15,468 (sd £25,534, accounting for 62% of overall care costs. Being younger and more disabled predicted higher formal care costs, explaining 32% and 30% of the variation in costs respectively at six and twelve months. CONCLUSION: Community services for people with LTNCs carry substantial costs that shift from health to social care over time, increasing the burden on families. Prioritising rehabilitation services towards those in greatest need could limit access to others needing on

  19. A possible association between space weather conditions and the risk of acute coronary syndrome in patients with diabetes and the metabolic syndrome

    Science.gov (United States)

    Vencloviene, Jone; Babarskiene, Ruta Marija; Kiznys, Deivydas

    2017-01-01

    Hyperglycemia negatively affects cardiovascular variables that are also adversely affected by increased geomagnetic activity. It is likely that geomagnetic storms (GS) could have a stronger negative impact on these patients. We analyzed data on 1548 randomly selected patients with acute coronary syndrome (ACS) who were admitted inpatient treatment in Kaunas city, during 2000-2003. We evaluated the associations of GS, solar proton events (SPE), and high-speed solar wind (HSSW) (solar wind speed ≥600 km/s) with the risk of ACS in patients with diabetes mellitus (DM) and the metabolic syndrome (MS) by using logistic regression with categorical predictors. During days of HSSW, the risk of ACS in DM patients increased by 1.95 times (OR = 1.95, 95 % CI 1.36-2.79) as compared to days without either of these events or 2 days prior to or after them. In the multivariate model, the risk of ACS in DM patients was associated with days of HSSW and 1-2 days after (OR = 1.40, 95 % CI 1.01-1.93), with days of GS lasting >1 day and occurring on days of HSSW or 1-2 days after (OR = 2.31, 95 % CI 1.28-4.17), and with the onset of SPE (OR = 2.72 (1.09-6.83)). The risk of ACS in MS patients was associated with days of GS and 1-2 days prior or after GS (OR = 1.31 (1.00-1.73)); an additional impact was established if these days coincided with days of HSSW or 1-2 days before (OR = 2.16 (1.39-3.35)). These findings suggest that not only GS but also HSSW and changes in space weather conditions prior to SPE affect the human cardiovascular system.

  20. Cost-competitiveness of organic photovoltaics for electricity self-consumption at residential buildings: A comparative study of Denmark and Greece under real market conditions

    DEFF Research Database (Denmark)

    Chatzisideris, Marios Dimos; Laurent, Alexis; Christoforidis, Georgios C.

    2017-01-01

    To address sustainability challenges, photovoltaics (PV) are regarded as a promising renewable energy technology. Decreasing PV module costs and increasing residential electricity prices have made self-consumption of PV-generated electricity financially more attractive than exporting to the grid....... Organic photovoltaics (OPV) are an emerging thin-film PV technology that shows promise of greatly improving the environmental and economic performances of PV technologies. Previous studies have estimated the current and future costs of OPV technologies, but the attractiveness of investing in OPV systems...

  1. Deep Space Telecommunications

    Science.gov (United States)

    Kuiper, T. B. H.; Resch, G. M.

    2000-01-01

    The increasing load on NASA's deep Space Network, the new capabilities for deep space missions inherent in a next-generation radio telescope, and the potential of new telescope technology for reducing construction and operation costs suggest a natural marriage between radio astronomy and deep space telecommunications in developing advanced radio telescope concepts.

  2. Energy density and storage capacity cost comparison of conceptual solid and liquid sorption seasonal heat storage systems for low-temperature space heating

    NARCIS (Netherlands)

    Scapino, L.; Zondag, H.A.; Van Bael, J.; Diriken, J.; Rindt, C.C.M.

    Sorption heat storage can potentially store thermal energy for long time periods with a higher energy density compared to conventional storage technologies. A performance comparison in terms of energy density and storage capacity costs of different sorption system concepts used for seasonal heat

  3. Effect of different plant spacing on the production of cauliflower (Brassica oleraceae var. Botrytis) under the agro-climatic conditions of D.I. Khan.

    Science.gov (United States)

    Mujeeb-ur-Rahman; Iqbal, Muhammad; Jilani, Muhammad Saleem; Waseem, Kashif

    2007-12-15

    A research project to evaluate the effect of different plant spacing on the production of cauliflower was conducted at Horticulture Research Area, Faculty of Agriculture, Gomal University, Dera Ismail Khan, NWFP, Pakistan. Six different plant spacing viz., 30, 35, 40, 45, 50 and 55 cm were used. The results revealed significant variations in all the parameters and amongst various plant spacing, 45 cm spacing showed the best response for all the parameters. Maximum plant height (49.33 cm), curd diameter (19.13 cm), maximum curd weight (1.23 kg plant(-1)) and yield (30.77 t ha(-1)) were recorded in the plots where the plants were spaced 45 cm apart.

  4. Well posedness and regularity for heat equation with the initial condition in weighted Orlitz-Slobodetskii space subordinated to Orlicz space like lambda (log lambda0alpha and the logarithmic weight

    Czech Academy of Sciences Publication Activity Database

    Kałamajska, A.; Krbec, Miroslav

    2015-01-01

    Roč. 28, č. 3 (2015), s. 677-713 ISSN 1139-1138 R&D Projects: GA ČR GAP201/10/1920 Institutional research plan: CEZ:AV0Z1019905 Keywords : evolution problems * heat equation * Orlitz-Slobodetskii spaces * Orlitz-Sobolev spaces Subject RIV: BA - General Mathematics Impact factor: 0.631, year: 2015 http://link.springer.com/article/10.1007%2Fs13163-014-0164-4

  5. The Small Payload Access to Space Experiment (SPASE): Using Non-Traditional Aerospace Technology to Enable a New Generation of Low-Cost Missions

    OpenAIRE

    McDermott, Scott; Aamot, L. Eric

    2001-01-01

    Launching on STS-108 Endeavour in late 2001, the Small Payload Access to Space Experiment (SPASE) demonstrates a number of new technologies, efficient ways to conduct a nanospacecraft development program, and how to take such a spacecraft through the Shuttle Hitchhiker safety and integration process. This paper describes the essential “lessons learned” in each of these areas. Commercial solar panels, batteries, imagers, photocells, integrated circuits, and manufacturing techniques are used th...

  6. Product Characteristics, Market Conditions and Contract Type: U.S. Department of Defense Use of Fixed-Price and Cost Reimbursement Contracts

    Science.gov (United States)

    2015-07-27

    Empirica, 30(2), 149-161. Dijkgraaf, E.; & Gradus, R. (2008). Institutional developments in the Dutch waste-collection market. Environment and...Management responses in noncompetitive markets. Public Administration Review, 72(6), 887-900. Hakim, S.; & Blackstone , E. (2013). Cost analysis of...Hefetz, A. (2003). Rural-urban differences in privatization: Limits to the competitive state. Environment and Planning C: Government and Policy, 21(5

  7. Space Debris & its Mitigation

    Science.gov (United States)

    Kaushal, Sourabh; Arora, Nishant

    2012-07-01

    Space debris has become a growing concern in recent years, since collisions at orbital velocities can be highly damaging to functioning satellites and can also produce even more space debris in the process. Some spacecraft, like the International Space Station, are now armored to deal with this hazard but armor and mitigation measures can be prohibitively costly when trying to protect satellites or human spaceflight vehicles like the shuttle. This paper describes the current orbital debris environment, outline its main sources, and identify mitigation measures to reduce orbital debris growth by controlling these sources. We studied the literature on the topic Space Debris. We have proposed some methods to solve this problem of space debris. We have also highlighted the shortcomings of already proposed methods by space experts and we have proposed some modification in those methods. Some of them can be very effective in the process of mitigation of space debris, but some of them need some modification. Recently proposed methods by space experts are maneuver, shielding of space elevator with the foil, vaporizing or redirecting of space debris back to earth with the help of laser, use of aerogel as a protective layer, construction of large junkyards around international space station, use of electrodynamics tether & the latest method proposed is the use of nano satellites in the clearing of the space debris. Limitations of the already proposed methods are as follows: - Maneuvering can't be the final solution to our problem as it is the act of self-defence. - Shielding can't be done on the parts like solar panels and optical devices. - Vaporizing or redirecting of space debris can affect the human life on earth if it is not done in proper manner. - Aerogel has a threshold limit up to which it can bear (resist) the impact of collision. - Large junkyards can be effective only for large sized debris. In this paper we propose: A. The Use of Nano Tubes by creating a mesh

  8. Present condition and theme of the planning standards of parks and open space planning. Koen ryokuchi keikaku gijutsu hyojun no genjo to kadai

    Energy Technology Data Exchange (ETDEWEB)

    Takanashi, M. (Kanagawa Prefectural Government, Kanagawa (Japan))

    1992-08-06

    With the dramatic progress of urbanization, the rapid decrease of the green area and the open space, which is basis for ensuring the safety and the comfort of city life and formation of a good city environment, lead to the worsen of city environment. For the basic purpose of achieving the harmony between development and environment by considering the preservation of the green area and the open space, the green master plan is a representative example, and was made as the constitution of from a ground plan to the various plans such as region, city and nation based on the space unit of developing the human action. One of the important planning approach for the green area plan from conception to implementation is the planning standards of park and open space planning. This paper introduced the change of the system about the planning standards of park and open space planning, and explained necessarily the present state of greens master plan about preservation of the national environment and adjustment the park and open space. 1tab.

  9. Radon reduction in crawl-space houses

    International Nuclear Information System (INIS)

    Osborne, M.C.; Moore, D.G.; Southerlan, R.E.; Brennan, T.; Pyle, B.E.

    1989-01-01

    This paper gives results of an EPA study of radon-mitigation alternatives for crawl space houses in several houses in Nashville, TN. Application of one of these alternative mitigation options, suction under a polyethylene membrane, has been successful in significantly reducing radon levels in both the crawl space and the house. The large radon concentrations measured under unvented plastic ground covers and the moisture barriers found in many crawl spaces can act as radon-rich reservoirs capable of contaminating a crawl space and house during periods of depressurization. With the exhaust components of the mitigation system in place, radon levels below the plastic decreased by more than 95% under both passive and active suction conditions. Based on the study, the design of a cost-effective subplastic suction passive radon mitigation system for crawl spaces seems promising

  10. Sociodemographic variations in the amount, duration and cost of potentially preventable hospitalisation for chronic conditions among Aboriginal and non-Aboriginal Australians: a period prevalence study of linked public hospital data

    OpenAIRE

    Banham, David; Chen, Tenglong; Karnon, Jonathan; Brown, Alex; Lynch, John

    2017-01-01

    Objectives To determine disparities in rates, length of stay (LOS) and hospital costs of potentially preventable hospitalisations (PPH) for selected chronic conditions among Aboriginal and non-Aboriginal South Australians (SA), then examine associations with area-level socioeconomic disadvantage and remoteness. Setting Period prevalence study using linked, administrative public hospital records. Participants Participants included all SA residents in 2005–2006 to 2010–2011. Analysis focused on...

  11. Heating, Ventilation, and Air Conditioning Design Strategy for a Hot-Humid Production Builder

    Energy Technology Data Exchange (ETDEWEB)

    Kerrigan, P. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-03-01

    BSC worked directly with the David Weekley Homes - Houston division to redesign three floor plans in order to locate the HVAC system in conditioned space. The purpose of this project is to develop a cost effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses. This is in preparation for the upcoming code changes in 2015. The builder wishes to develop an upgrade package that will allow for a seamless transition to the new code mandate. The following research questions were addressed by this research project: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences? 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost? BSC and the builder developed a duct design strategy that employs a system of dropped ceilings and attic coffers for moving the ductwork from the vented attic to conditioned space. The furnace has been moved to either a mechanical closet in the conditioned living space or a coffered space in the attic.

  12. Implementation of a Novel Low-Cost Low-Profile Ku-Band Antenna Array for Single Beam Steering from Space

    Science.gov (United States)

    Host, Nicholas K.; Chen, Chi-Chih; Volakis, John L.; Miranda, Felix A.

    2013-01-01

    Phased array antennas afford many advantages over traditional reflector antennas due to their conformality, high aperture efficiency, and unfettered beam steering capability at the price of increased cost and complexity. This paper eliminates the complex and costly array backend via the implementation of a series fed array employing a propagation constant reconfigurable transmission line connecting each element in series. Scanning can then be accomplished through one small (less than or equal to 100mil) linear motion that controls propagation constant. Specifically, each element is fed via a reconfigurable coplanar stripline transmission line with a tapered dielectric insert positioned between the transmission line traces. The dielectric insert is allowed to move up and down to control propagation constant and therefore induce scanning. We present a 20 element patch array design, scanning from -25 deg. less than or equal to theta less than or equal to 21 deg. at 13GHz. Measurements achieve only10.5 deg. less than or equal to theta less than or equal to 22 deg. scanning due to a faulty, yet correctable, manufacturing process. Beam squint is measured to be plus or minus 3 deg. for a 600MHz bandwidth. This prototype was improved to give scanning of 3.5 deg. less than or equal to theta less than or equal to 22 deg. Cross-pol patterns were shown to be -15dB below the main beam. Simulations accounting for fabrication errors match measured patterns, thus validating the designs.

  13. Large size space construction for space exploitation

    Science.gov (United States)

    Kondyurin, Alexey

    2016-07-01

    Space exploitation is impossible without large space structures. We need to make sufficient large volume of pressurized protecting frames for crew, passengers, space processing equipment, & etc. We have to be unlimited in space. Now the size and mass of space constructions are limited by possibility of a launch vehicle. It limits our future in exploitation of space by humans and in development of space industry. Large-size space construction can be made with using of the curing technology of the fibers-filled composites and a reactionable matrix applied directly in free space. For curing the fabric impregnated with a liquid matrix (prepreg) is prepared in terrestrial conditions and shipped in a container to orbit. In due time the prepreg is unfolded by inflating. After polymerization reaction, the durable construction can be fitted out with air, apparatus and life support systems. Our experimental studies of the curing processes in the simulated free space environment showed that the curing of composite in free space is possible. The large-size space construction can be developed. A project of space station, Moon base, Mars base, mining station, interplanet space ship, telecommunication station, space observatory, space factory, antenna dish, radiation shield, solar sail is proposed and overviewed. The study was supported by Humboldt Foundation, ESA (contract 17083/03/NL/SFe), NASA program of the stratospheric balloons and RFBR grants (05-08-18277, 12-08-00970 and 14-08-96011).

  14. Cost-utility of collaborative care for the treatment of comorbid major depressive disorder in outpatients with chronic physical conditions. A randomized controlled trial in the general hospital setting (CC-DIM

    Directory of Open Access Journals (Sweden)

    Goorden M

    2017-07-01

    Full Text Available Maartje Goorden,1 Christina M van der Feltz-Cornelis,2,3 Kirsten M van Steenbergen-Weijenburg,4 Eva K Horn,5 Aartjan TF Beekman,6,7 Leona Hakkaart-van Roijen1 1Institute of Health Policy and Management (iBMG/Institute for Medical Technology Assessment (iMTA, Erasmus University Rotterdam, Rotterdam, 2Tranzo Department, Tilburg University, 3Clinical Centre of Excellence for Body, Mind and Health, GGzBreburg, Tilburg, 4Trimbos Instituut, Utrecht, 5Viersprong Institute for Studies on Personality Disorders, Halsteren, 6Department of Psychiatry, 7EMGO+ Research Institute VUmc, VU University Medical Centre, Amsterdam, the Netherlands Purpose: Major depressive disorder (MDD is highly prevalent in patients with a chronic physical condition, and this comorbidity has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Research has shown that collaborative care (CC may be a cost-effective treatment. However, its cost-effectiveness in this patient group has not yet been established. Therefore, the aim of this study was to evaluate the cost-utility of CC for the treatment of comorbid MDD in chronically ill patients in the outpatient general hospital setting. The study was conducted from a health care and societal perspective.Patients and methods: In this randomized controlled trial, 81 patients with moderate-to-severe MDD were included; 42 were randomly assigned to the CC group and 39 to the care as usual (CAU group. We applied the TiC-P, short-form Health-Related Quality of Life questionnaire, and EuroQol EQ-5D 3 level version, measuring the use of health care, informal care, and household work, respectively, at baseline and at 3, 6, 9, and 12 months follow-up.Results: The mean annual direct medical costs in the CC group were €6,718 (95% confidence interval [CI]: 3,541 to 10,680 compared to €4,582 (95% CI: 2,782 to 6,740 in the CAU group. The average quality-adjusted life years (QALYs gained were 0.07 higher

  15. Hybrid coolers under part-load conditions - Optimisation of operating costs and energy consumption; Simulation und Berechnung von hybriden Trockenkuehlern imTeillastbereich - Optimierung von Betriebskosten und Energieverbrauch

    Energy Technology Data Exchange (ETDEWEB)

    Koenig, H.

    2007-07-01

    This comprehensive article takes a look at new European guidelines on the energy performance of buildings in which the total efficiency of the buildings or heat-transportation systems under partial loading is considered. On the basis of a real-life example, the author examines the influence of various components such as compressors, pumps and ventilators on energy consumption. Hybrid coolers are looked at and the characteristics of refrigeration machines with respect to varying outside temperature are discussed. Combined cooling for computer centres is examined and switchable, redundant combined systems are looked at. Optimisation of cooling systems for falling outside temperatures and the operation of cold-water systems are looked at. Simulation topics are discussed and optimisation with respect to costs and energy consumption are examined.

  16. Comparative analysis of the efficiency, reliability, technical feasibility and costs of methods to convert sewage sludge to a hygienically safe condition

    International Nuclear Information System (INIS)

    Fuhrmann, D.; Leschber, R.; Mueller, G.; Jaeger, B.; Neumann, U.

    1981-01-01

    Due to the development of sewage treatment technology and the construction of new and sewage works and enlargement of older ones, increasing amounts of sewage sludge have been produced. Agricultural use of municipal sewage sludge is a practicable way of utilization which, however, is often limited for reasons of hygienic safety. The present study intends to describe methods of sewage sludge disinfection which have been used in practice or tested extensively, as well as technical innovations in this field, and to give information on their performance with respect to hygienic and technical requirements. A direct comparison of processes has turned out to be extremely difficult because disinfection of sewage sludge is only one of the stages of sewage treatment. For comparison, numerous factors have to be taken into account such as plant size, type of sewage and sludge treatment processes, energy costs, sales potential for agricultural use etc. This study is meant as an aid in such work. (orig.) [de

  17. Space Sciences Focus Area

    Energy Technology Data Exchange (ETDEWEB)

    Reeves, Geoffrey D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-10

    To advance our understanding of the space environment (from the Sun to the Earth and beyond) and to advance our ability to operate systems in space that protect life and society. Space Science is distinct from other field, such as astrophysics or cosmology, in that Space Science utilizes in-situ measurements from high altitude rockets, balloons and spacecraft or ground-based measurements of objects and conditions in space.

  18. Collaborative Commercial Space Situational Awareness

    Science.gov (United States)

    Kelso, T. S.; Hendrix, D.; Sibert, D.; Hall, R. A.; Therien, W.

    2013-09-01

    There is an increasing recognition by commercial and civil space operators of the need for space situational awareness (SSA) data to support ongoing conjunction analysis, maneuver planning, and radio frequency interference mitigation as part of daily operations. While some SSA data is available from the Joint Space Operations Center via the Space Track web site, access to raw observations and photometric data is limited due to national security considerations. These data, however, are of significant value in calibrating intra- and inter-operator orbit determination results, determining inter-system biases, and assessing operating profiles in the geostationary orbit. This paper details an ongoing collaborative effort to collect and process optical observations and photometric data using a network of low-cost telescope installations and shows how these data are being used to support ongoing operations in the Space Data Center. This presentation will demonstrate how by leveraging advance photometric processing algorithms developed for Missile Defense Agency and the Ballistic Missile Defense (BMD) mission ExoAnalytic and AGI have been able to provide actionable SSA for satellite operators from small telescopes in less than optimal viewing conditions. Space has become an increasingly cluttered environment requiring satellite operators to remain forever vigilant in order to prevent collisions to preserve their assets and prevent further cluttering the space environment. The Joint Space Operations Center (JSpOC), which tracks all objects in earth orbit, reports possible upcoming conjunctions to operators by providing Conjunction Summary Messages (CSMs). However due to large positional uncertainties in the forward predicted position of space objects at the time closest approach the volume of CSMs is excessive to the point that maneuvers in response to CSMs without additional screening is cost prohibitive. CSSI and the Space Data Association have been able to screen most

  19. Space polypropulsion

    CSIR Research Space (South Africa)

    Kellett, BJ

    2008-04-01

    Full Text Available understandably, fallen by the wayside. NASAs putative atom bomb propelled mission, coincidently also baptized ORION, was also curtailed. And last of all, the use of lasers for propulsion remains firmly “stuck in the doldrums.” This mode of access to space...) Except for LOX, very polluting. V. high ζ Launch costs: $20,000/kg. Gas guns. 1 1-4 km/s Most of the system mass stays on the ground. Recoil problems. Large NASA gas gun project abandoned. (too many “g’s”) E-M guns: rail/coil. 1.5 1-10 km...

  20. Design of annual storage solar space heating systems

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, F C; Cook, J D

    1979-11-01

    Design considerations for annual storage solar space heating systems are discussed. A simulation model for the performance of suh systems is described, and a method of classifying system configurations is proposed. It is shown that annual systems sized for unconstrained performance, with no unused collector or storage capacity, and no rejected heat, minimize solar acquisition costs. The optimal performance corresponds to the condition where the marginal storage-to-collector sizing ratio is equal to the corresponding marginal cost ratio.

  1. H 2 guaranteed cost control of discrete linear systems

    Directory of Open Access Journals (Sweden)

    Colmenares W.

    2000-01-01

    Full Text Available This paper presents necessary and sufficient conditions for the existence of a quadratically stabilizing output feedback controller which also assures H 2 guaranteed cost performance on a discrete linear uncertain system where the uncertainty is of the norm bounded type. The conditions are presented as a collection of linear matrix inequalities.The solution, however requires a search over a scalar parameter space.

  2. Study of counter current flow limitation model of MARS-KS and SPACE codes under Dukler's air/water flooding test conditions

    International Nuclear Information System (INIS)

    Lee, Won Woong; Kim, Min Gil; Lee, Jeong Ik; Bang, Young Seok

    2015-01-01

    In particular, CCFL(the counter current flow limitation) occurs in components such as hot leg, downcomer annulus and steam generator inlet plenum during LOCA which is possible to have flows in two opposite directions. Therefore, CCFL is one of the thermal-hydraulic models which has significant effect on the reactor safety analysis code performance. In this study, the CCFL model will be evaluated with MARS-KS based on two-phase two-field governing equations and SPACE code based on two-phase three-field governing equations. This study will be conducted by comparing MARS-KS code which is being used for evaluating the safety of a Korean Nuclear Power Plant and SPACE code which is currently under assessment for evaluating the safety of the designed nuclear power plant. In this study, comparison of the results of liquid upflow and liquid downflow rate for different gas flow rate from two code to the famous Dukler's CCFL experimental data are presented. This study will be helpful to understand the difference between system analysis codes with different governing equations, models and correlations, and further improving the accuracy of system analysis codes. In the nuclear reactor system, CCFL is an important phenomenon for evaluating the safety of nuclear reactors. This is because CCFL phenomenon can limit injection of ECCS water when CCFL occurs in components such as hot leg, downcomer annulus or steam generator inlet plenum during LOCA which is possible to flow in two opposite directions. Therefore, CCFL is one of the thermal-hydraulic models which has significant effect on the reactor safety analysis code performance. In this study, the CCFL model was evaluated with MARS-KS and SPACE codes for studying the difference between system analysis codes with different governing equations, models and correlations. This study was conducted by comparing MARS-KS and SPACE code results of liquid upflow and liquid downflow rate for different gas flow rate to the famous Dukler

  3. Determination of cost-effective operating condition for CO{sub 2} capturing using 1-butyl-3-methylimidazolium tetrafluoroborate ionic liquid

    Energy Technology Data Exchange (ETDEWEB)

    Ali, Emad; Alnashef, Inas; Ajbar, Abdelhamid; Mulyono, Sarwono; Hadj-Kali, Mohamed Kamel [King Saud University, Riyadh (Saudi Arabia); Hizaddin, Hanee Farzana [University of Malaya, Kuala Lumpur (Malaysia)

    2013-11-15

    1-Butyl-3-methylimidazolium tetrafluoroborate ([BMIM][BF4]) ionic liquid (IL) is considered for CO{sub 2} capturing in a typical absorption/stripper process. The use of ionic liquids is considered to be cost-effective because it requires less energy for solvent recovery compared to other conventional processes. A mathematical model was developed for the process based on Peng-Robinson (PR) equation of state (EoS). The model was validated with experimental data for CO{sub 2} solubility in [BMIM][BF4]. The model is utilized to study the sorbent effect and energy demand for selected operating pressure at specific CO{sub 2} capturing rates. The energy demand is expressed by the vapor-liquid equilibrium temperature necessary to remove the captured CO{sub 2} from the spent solvent in the regeneration step. It is found that low recovery temperature can be achieved at specific pressure combination for the absorber/stripper units. In fact, the temperature requirement is less than that required by the typical monoethanolamine (MEA) solvent. The effect of the CO{sub 2} loading in the sorbent stream on the process performance is also examined.

  4. Measuring the cost of care in benign prostatic hyperplasia using time-driven activity-based costing (TDABC).

    Science.gov (United States)

    Kaplan, A L; Agarwal, N; Setlur, N P; Tan, H J; Niedzwiecki, D; McLaughlin, N; Burke, M A; Steinberg, K; Chamie, K; Saigal, C S

    2015-03-01

    Determining '"value'" in health care, defined as outcomes per unit cost, depends on accurately measuring cost. We used time-driven activity-based costing (TDABC) to determine the cost of care in men with benign prostatic hyperplasia (BPH) - a common urologic condition. We implemented TDABC across the entire care pathway for BPH including primary and specialist care in both inpatient and outpatient settings. A team of expert stakeholders created detailed process maps, determined space and product costs, and calculated personnel capacity cost rates. A model pathway was derived from practice guidelines and calculated costs were applied. Although listed as 'optional' in practice guidelines, invasive diagnostic testing can increase costs by 150% compared with the standalone urology clinic visit. Of five different surgical options, a 400% cost discrepancy exists between the most and least expensive treatments. TDABC can be used to measure cost across an entire care pathway in a large academic medical center. Sizable cost variation exists between diagnostic and surgical modalities for men with BPH. As financial risk is shifted toward providers, understanding the cost of care will be vital. Future work is needed to determine outcome discrepancy between the diagnostic and surgical modalities in BPH. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. 任意光照下人脸图像的低维光照空间表示%A Low-dimensional Illumination Space Representation of Human Faces for Arbitrary Lighting Conditions

    Institute of Scientific and Technical Information of China (English)

    胡元奎; 汪增福

    2007-01-01

    The proposed method for low-dimensional illumination space representation (LDISR) of human faces can not only synthesize a virtual face image when given lighting conditions but also estimate lighting conditions when given a face image. The LDISR is based on the observation that 9 basis point light sources can represent almost arbitrary lighting conditions for face recognition application and different human faces have a similar LDISR. The principal component analysis (PCA) and the nearest neighbor clustering method are adopted to obtain the 9 basis point light sources. The 9 basis images under the 9 basis point light sources are then used to construct an LDISR which can represent almost all face images under arbitrary lighting conditions.Illumination ratio image (IRI) is employed to generate virtual face images under different illuminations. The LDISR obtained from face images of one person can be used for other people. Experimental results on image reconstruction and face recognition indicate the efficiency of LDISR.

  6. Space Nuclear Reactor Engineering

    Energy Technology Data Exchange (ETDEWEB)

    Poston, David Irvin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-06

    We needed to find a space reactor concept that could be attractive to NASA for flight and proven with a rapid turnaround, low-cost nuclear test. Heat-pipe-cooled reactors coupled to Stirling engines long identified as the easiest path to near-term, low-cost concept.

  7. Costly location in Hotelling duopoly

    NARCIS (Netherlands)

    Hinloopen, J.; Martin, S.

    2013-01-01

    We introduce a cost of location into Hotelling’s (1929) spatial duopoly. We derive the general conditions on the cost-of-location function under which a pure strategy price-location Nash equilibrium exists. With linear transportation cost and a suitably specified cost of location that rises toward

  8. Costly location in Hotelling duopoly

    NARCIS (Netherlands)

    Hinloopen, J.; Martin, S.

    We introduce a cost of location into Hotelling's (1929) spatial duopoly model. We derive the general conditions on the cost-of-location function under which a pure strategy price-location Nash equilibrium exists. With linear transportation cost and a suitably specified cost of location that rises

  9. Cost Accounting for Decision Makers.

    Science.gov (United States)

    Kaneklides, Ann L.

    1985-01-01

    Underscores the importance of informed decision making through accurate anticipation of cost incurrence in light of changing economic and environmental conditions. Explains the concepts of cost accounting, full allocation of costs, the selection of an allocation base, the allocation of indirect costs, depreciation, and implications for community…

  10. A condition for the overflow stability of second-order digital filters that is satisfied by all scaled state-space structures using saturation

    NARCIS (Netherlands)

    Ritzerfeld, J.H.F.

    1989-01-01

    A set of conditions is derived that ensures overflow stability of second-order digital filters for different classes of overflow arithmetics, involving only the elements of the state-transition matrix. The well-known arithmetic saturation, zeroing, and two's-complement lead to different stability

  11. Sociodemographic variations in the amount, duration and cost of potentially preventable hospitalisation for chronic conditions among Aboriginal and non-Aboriginal Australians: a period prevalence study of linked public hospital data.

    Science.gov (United States)

    Banham, David; Chen, Tenglong; Karnon, Jonathan; Brown, Alex; Lynch, John

    2017-10-15

    To determine disparities in rates, length of stay (LOS) and hospital costs of potentially preventable hospitalisations (PPH) for selected chronic conditions among Aboriginal and non-Aboriginal South Australians (SA), then examine associations with area-level socioeconomic disadvantage and remoteness. Period prevalence study using linked, administrative public hospital records. Participants included all SA residents in 2005-2006 to 2010-2011. Analysis focused on those individuals experiencing chronic PPH as defined by the Australian Institute of Health and Welfare. Number and rates (unadjusted, then adjusted for sex and age) of chronic PPH, total LOS and direct hospital costs by Aboriginality. Aboriginal SAs experienced higher risk of index chronic PPH compared with non-Aboriginals (11.5 and 6.2 per 1000 persons per year, respectively) and at younger ages (median age 48 vs 70 years). Once hospitalised, Aboriginal people experienced more chronic PPH events, longer total LOS with higher costs than non-Aboriginal people (2.6 vs 1.9 PPH per person; 11.7 vs 9.0 days LOS; at $A17 928 vs $A11 515, respectively). Compared with population average LOS, the standardised rate ratio of LOS among Aboriginal people increased by 0.03 (95% CI 0.00 to 0.07) as disadvantage rank increased and 1.04 (95% CI 0.63 to 1.44) as remoteness increased. Non-Aboriginal LOS also increased as disadvantage increased but at a lower rate (0.01 (95% CI 0.01 to 0.01)). Costs of Aboriginal chronic PPH increased by 0.02 (95% CI 0.00 to 0.06) for each increase in disadvantage and 1.18 (95% CI 0.80 to 1.55) for increased remoteness. Non-Aboriginal costs also increased as disadvantage increased but at lower rates (0.01 (95% CI 0.01 to 0.01)). Aboriginal people's heightened risk of chronic PPH resulted in more time in hospital and greater cost. Systematic disparities in chronic PPH by Aboriginality, area disadvantage and remoteness highlight the need for improved uptake of effective primary care. Routine

  12. Analyzing the non-stationary space relationship of a city's degree of vegetation and social economic conditions in Shanghai, China using OLS and GWR models

    Science.gov (United States)

    Wang, Kejing; Zhang, Yuan; An, Youzhi; Jing, Zhuoxin; Wang, Chao

    2013-09-01

    With the fast urbanization process, how does the vegetation environment change in one of the most economically developed metropolis, Shanghai in East China? To answer this question, there is a pressing demand to explore the non-stationary relationship between socio-economic conditions and vegetation across Shanghai. In this study, environmental data on vegetation cover, the Normalized Difference Vegetation Index (NDVI) derived from MODIS imagery in 2003 were integrated with socio-economic data to reflect the city's vegetative conditions at the census block group level. To explore regional variations in the relationship of vegetation and socio-economic conditions, Ordinary Least Squares (OLS) and Geographically Weighted Regression (GWR) models were applied to characterize mean NDVI against three independent socio-economic variables, an urban land use ratio, Gross Domestic Product (GDP) and population density. The study results show that a considerable distinctive spatial variation exists in the relationship for each model. The GWR model has superior effects and higher precision than the OLS model at the census block group scale. So, it is more suitable to account for local effects and geographical variations. This study also indicates that unreasonable excessive urbanization, together with non-sustainable economic development, has a negative influence of vegetation vigor for some neighborhoods in Shanghai.

  13. Base pressure and heat transfer tests of the 0.0225-scale space shuttle plume simulation model (19-OTS) in yawed flight conditions in the NASA-Lewis 10x10-foot supersonic wind tunnel (test IH83)

    Science.gov (United States)

    Foust, J. W.

    1979-01-01

    Wind tunnel tests were performed to determine pressures, heat transfer rates, and gas recovery temperatures in the base region of a rocket firing model of the space shuttle integrated vehicle during simulated yawed flight conditions. First and second stage flight of the space shuttle were simulated by firing the main engines in conjunction with the SRB rocket motors or only the SSME's into the continuous tunnel airstream. For the correct rocket plume environment, the simulated altitude pressures were halved to maintain the rocket chamber/altitude pressure ratio. Tunnel freestream Mach numbers from 2.2 to 3.5 were simulated over an altitude range of 60 to 130 thousand feet with varying angle of attack, yaw angle, nozzle gimbal angle and SRB chamber pressure. Gas recovery temperature data derived from nine gas temperature probe runs are presented. The model configuration, instrumentation, test procedures, and data reduction are described.

  14. Continuous laser irradiation under ambient conditions: A simple way for the space-selective growth of gold nanoparticles inside a silica monolith

    International Nuclear Information System (INIS)

    El Hamzaoui, Hicham; Bernard, Remy; Chahadih, Abdallah; Chassagneux, Fernand; Bois, Laurence; Capoen, Bruno; Bouazaoui, Mohamed

    2011-01-01

    Highlights: → Visible continuous laser direct-write gold nanoparticles inside a silica monolith. → The presence of the additive (Na 2 CO 3 ) is not necessary to the growth of gold nanoparticles. → A simple heat treatment leads to precipitation of gold nanoparticles inside the silica matrices with, or without, the additive. → The local precipitation of gold nanoparticles by continuous photo-irradiation occurs following a photo-thermal activated mechanism. -- Abstract: Thanks to the potential and various applications of metal-dielectric nanocomposites, their syntheses constitute an interesting subject in material research. In this work, we demonstrate the achievement of gold nanocrystals growth through a visible and continuous laser irradiation. The in situ and direct space-selective generation of metallic nanoparticles is localized under the surface within transparent silica monoliths. For that purpose, the porous silica monoliths are prepared using a sol-gel route and post-doped with gold precursors before the irradiation. The presence of Au nanoparticles inside the irradiated areas was evidenced using absorption spectroscopy, X-ray diffraction analysis and transmission electron microscopy. The comparison between the results obtained after a laser irradiation and by a simple heat-treatment reveals that the local precipitation of gold nanoparticles by continuous photo-irradiation occurs following a photo-thermal activated mechanism.

  15. Heating, Ventilation, and Air Conditioning Design Strategy for a Hot-Humid Production Builder

    Energy Technology Data Exchange (ETDEWEB)

    Kerrigan, P. [Building Science Corporation, Somerville, MA (United States)

    2014-03-01

    Building Science Corporation (BSC) worked directly with the David Weekley Homes - Houston division to develop a cost-effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses in preparation for the upcoming code changes in 2015. This research project addressed the following questions: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences? 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost?

  16. Sistema de bajo costo para el monitoreo por condición a aplicar en parques eólicos.; Low-cost condition monitoring system to be applied on wind turbines

    Directory of Open Access Journals (Sweden)

    Fidel Ernesto Hernández Montero

    2011-05-01

    Full Text Available El siguiente trabajo tiene como objetivo ofrecer una visión del panorama general relativo a la aplicación de las tecnologías de monitoreo por condición y de detección de fallos en el campo de la industria de energía eólica. En primer lugar, el trabajo va dirigido a analizar diversas experiencias de aplicación del mantenimiento basado en la condición en la industria eólica, específicamente para demostrar la factibilidad de su implementación. Se continúa con un estudio de los fallos más severos que se generan en las turbinas eólicas y se describe la tendencia actual de la implementación de los sistemas de monitoreo por condición y de detección de fallos. Finalmente se presenta una propuesta de sistema de monitoreo por condición de bajo costo para implementar en parques eólicos.  This paper provides a general view of the condition monitoring and fault detection system applications on wind energy converters. Firstly, implementation feasibility of condition monitoring systems is shown by analyzing several applications of condition-based maintenance on wind energy converters. Afterwards, the most critical failures in wind energy converters are described and current trends in such condition monitoring system applications are analyzed. Finally, a low-cost condition monitoring system implementation, interesting to be applied in developing countries, is proposed.

  17. The Austrian Space Plan

    Science.gov (United States)

    Pseiner, K.; Balogh, W.

    2002-01-01

    After several years of preparation and discussion among the involved players, the Austrian Space Plan was approved for implementation in November 2001. Based on careful benchmarking and analysis of the capabilities of the Austrian space sector it aims to create excellent conditions for the sector's further development. The new space strategy embraces Austria's participation in the mandatory and optional programmes of the European Space Agency and establishes a National Space Programme supported by separate funding opportunities. A set of clearly-defined indicators ensures that the progress in implementing the Space Plan can be objectively judged through independent, annual reviews. The National Space Programme promotes international cooperation in space research and space activities with the aim to strengthen the role of space science and to better prepare Austrian space industry for the commercial space market. In the framework of the Space Plan the Austrian Space Agency has been tasked with integrating the industry's growing involvement in aeronautics activities to better utilize synergies with the space sector. This paper reviews the various steps leading to the approval of the new space strategy and discusses the hurdles mastered in this process. It reports on the Space Plan's first results, specifically taking into account projects involving international cooperation. For the first the Austria aerospace-sector can rely on an integrated strategy for aeronautics- and space activities which is firmly rooted in the efforts to enhance the country's R&D activities. It may also act as a useful example for other small space- using countries planning to enhance their involvement in space activities.

  18. Logistics costs of the enterprise

    Directory of Open Access Journals (Sweden)

    Andrea Rosová

    2007-06-01

    Full Text Available The article describe a problem of specification and systematization of enterprise’s logistics costs. With in a growing division of labour, also logistics costs increase their part in enterprises total costs.Almost all decisions about products and production in general, influence logistics processes even logistics costs and performances.In present is not clear enough, which of the cost-particles are relevant fot logistics costs, because some of logistics cost-particles accounts within overhead are charged together with costs of other sorts.Substantive step in the process of the monitoring and evidence of logistics costs is definition of this, that costs of enterprise´s processes will be inclusive in logistics costs and determining points of contact with the others departments (acquisition, production, sale etc.. After the specification of meditation processes, there is a need to choose applicable parameters for the expression of logistics performances. Besides logistics costs is needed to know logistics performances equivalent herewith at a cost of, therefore from the control side have for enterprise bigger value indices expressive correlation costs and performances(e.g. share of logistics unit costs performance.At the proposal and evidence of logistics costs and performances is needed consistently entertain an individual conditions of enterprise. Because the area of processes included strongly affects the size of account logistics costs and its share part in total costs of enterprise. Logistics costs are flow line between economy and logistics of the enterprise.

  19. Lever conditioned stimulus-directed autoshaping induced by saccharin-ethanol unconditioned stimulus solution: effects of ethanol concentration and trial spacing.

    Science.gov (United States)

    Tomie, Arthur; Festa, Eugene D; Sparta, Dennis R; Pohorecky, Larissa A

    2003-05-01

    Two experiments were designed to evaluate whether brief access to a saccharin-ethanol solution would function as an effective unconditioned stimulus (US) in Pavlovian-autoshaping procedures. In these experiments, the insertion of a lever conditioned stimulus (CS) was followed by the brief presentation of a sipper tube containing saccharin-ethanol US solution. Experience with this Pavlovian-autoshaping procedure engendered lever CS-directed autoshaping conditioned responses (CRs) in all rats. In Experiment 1, the concentration of ethanol [0%, 2%, 4%, 6%, or 8% (vol./vol.)] in 0.1% saccharin was systematically increased within subjects across autoshaping sessions to evaluate the relation between a rat's drinking and lever pressing. In Experiment 2, the mean intertrial interval (ITI) duration (60, 90, 120 s) was systematically increased within subjects across autoshaping sessions to evaluate the effect of ITI duration on drinking and lever pressing. A pseudoconditioning control group received lever CS randomly with respect to the saccharin-ethanol US solution. In Experiment 1, lever-press autoshaping CRs developed in all rats, and the tendency of a rat to drink an ethanol concentration was predictive of the performance of lever-press autoshaping CRs. In Experiment 2, longer ITIs induced more lever CS-directed responding, and CS-US paired procedures yielded more lever CS-directed responding than that observed in CS-US random procedures. Saccharin-ethanol is an effective US in Pavlovian-autoshaping procedures, inducing more CS-directed responding than in pseudoconditioning controls receiving CS-US random procedures. More lever CS-directed responding was observed when there was more drinking of the saccharin-ethanol US solution (Experiment 1); when the CS and US were paired, rather than random (Experiment 2); and with longer mean ITI durations (Experiment 2). This pattern of results is consistent with the hypothesis that lever CS-directed responding reflects performance

  20. Cost Behavior

    DEFF Research Database (Denmark)

    Hoffmann, Kira

    The objective of this dissertation is to investigate determinants and consequences of asymmetric cost behavior. Asymmetric cost behavior arises if the change in costs is different for increases in activity compared to equivalent decreases in activity. In this case, costs are termed “sticky......” if the change is less when activity falls than when activity rises, whereas costs are termed “anti-sticky” if the change is more when activity falls than when activity rises. Understanding such cost behavior is especially relevant for decision-makers and financial analysts that rely on accurate cost information...... to facilitate resource planning and earnings forecasting. As such, this dissertation relates to the topic of firm profitability and the interpretation of cost variability. The dissertation consists of three parts that are written in the form of separate academic papers. The following section briefly summarizes...

  1. Part A: Countermeasures to be taken after 1990 to ensure safe living conditions for the population affected by the Chernobyl accident in the USSR. A first evaluation of costs and doses averted

    International Nuclear Information System (INIS)

    Lochard, J.; Schneider, T.

    1992-01-01

    This part presents a first estimate of the cost and averted collective exposure of the potential relocation of the population from the affected territories of the BSSR, the RSFSR and the UKrSSR, to improve their living conditions following the Chernobyl accident. It is an input to the evaluation of the radiological consequences of the Chernobyl accident in the USSR. The general objective was to assess 'the concept which the USSR has evolved to enable the population to live safely in areas affected by radioactive contamination following the Chernobyl accident, and an evaluation of the effectiveness of the steps taken in these areas to safeguard the health of the population'. Specifically, this work aimed at evaluating protective measures from 1990 onwards

  2. Seasonal behavior and long-term trends of tropospheric ozone, its precursors and chemical conditions over Iran: A view from space

    Science.gov (United States)

    Choi, Yunsoo; Souri, Amir Hossein

    2015-04-01

    annual TCO (∼0.59 ± 0.56 DU yr-1) but decreases in minimum annual TCO (∼-0.42 ± 0.60 DU yr-1) caused by an increase in NO2 species and annual CO (∼-0.95 ± 0.41 × 1016 molec./cm2 yr-1) partly resulting from the transport of reduced CO. The time series of the HCHO/NO2 column ratio (a proxy for the chemical conditions) indicated that during the last decade, the cities of Tehran, Ahvaz, and Isfahan exhibited steady chemical conditions while Tabriz and Mashhad exhibited a change from NOx-saturated/mixed to more NOx-sensitive chemical conditions.

  3. Space Resources Roundtable 2

    Science.gov (United States)

    Ignatiev, A.

    2000-01-01

    Contents include following: Developing Technologies for Space Resource Utilization - Concept for a Planetary Engineering Research Institute. Results of a Conceptual Systems Analysis of Systems for 200 m Deep Sampling of the Martian Subsurface. The Role of Near-Earth Asteroids in Long-Term Platinum Supply. Core Drilling for Extra-Terrestrial Mining. Recommendations by the "LSP and Manufacturing" Group to the NSF-NASA Workshop on Autonomous Construction and Manufacturing for Space Electrical Power Systems. Plasma Processing of Lunar and Planetary Materials. Percussive Force Magnitude in Permafrost. Summary of the Issues Regarding the Martian Subsurface Explorer. A Costing Strategy for Manufacturing in Orbit Using Extraterrestrial Resources. Mine Planning for Asteroid Orebodies. Organic-based Dissolution of Silicates: A New Approach to Element Extraction from LunarRegohth. Historic Frontier Processes Active in Future Space-based Mineral Extraction. The Near-Earth Space Surveillance (NIESS) Mission: Discovery, Tracking, and Characterization of Asteroids, Comets, and Artificial Satellites with a microsatellite. Privatized Space Resource Property Ownership. The Fabrication of Silicon Solar Cells on the Moon Using In-Situ Resources. A New Strategy for Exploration Technology Development: The Human Exploration and Development of Space (HEDS) Exploratiori/Commercialization Technology Initiative. Space Resources for Space Tourism. Recovery of Volatiles from the Moon and Associated Issues. Preliminary Analysis of a Small Robot for Martian Regolith Excavation. The Registration of Space-based Property. Continuous Processing with Mars Gases. Drilling and Logging in Space; An Oil-Well Perspective. LORPEX for Power Surges: Drilling, Rock Crushing. An End-To-End Near-Earth Asteroid Resource Exploitation Plan. An Engineering and Cost Model for Human Space Settlement Architectures: Focus on Space Hotels and Moon/Mars Exploration. The Development and Realization of a Silicon-60-based

  4. Development of a Rational Design Space for Optimizing Mixing Conditions for Formation of Adhesive Mixtures for Dry-Powder Inhaler Formulations.

    Science.gov (United States)

    Sarkar, Saurabh; Minatovicz, Bruna; Thalberg, Kyrre; Chaudhuri, Bodhisattwa

    2017-01-01

    The purpose of the present study was to develop guidance toward rational choice of blenders and processing conditions to make robust and high performing adhesive mixtures for dry-powder inhalers and to develop quantitative experimental approaches for optimizing the process. Mixing behavior of carrier (LH100) and AstraZeneca fine lactose in high-shear and low-shear double cone blenders was systematically investigated. Process variables impacting the mixing performance were evaluated for both blenders. The performance of the blenders with respect to the mixing time, press-on forces, static charging, and abrasion of carrier fines was monitored, and for some of the parameters, distinct differences could be detected. A comparison table is presented, which can be used as a guidance to enable rational choice of blender and process parameters based on the user requirements. Segregation of adhesive mixtures during hopper discharge was also investigated. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  5. 14 CFR 151.41 - Project costs.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Project costs. 151.41 Section 151.41... FEDERAL AID TO AIRPORTS Rules and Procedures for Airport Development Projects § 151.41 Project costs. (a) For the purposes of subparts B and C, project costs consist of any costs involved in accomplishing a...

  6. How effective and cost-effective are innovative combinatorial technologies and practices for supporting older people with long-term conditions to remain well in the community? An evaluation protocol for an NHS Test Bed in North West England.

    Science.gov (United States)

    Varey, Sandra; Hernández, Alejandra; Palmer, Tom M; Mateus, Céu; Wilkinson, Joann; Dixon, Mandy; Milligan, Christine

    2018-02-28

    The Lancashire and Cumbria Innovation Alliance (LCIA) Test Bed is a partnership between the National Health Service in England, industry (led by Philips) and Lancaster University. Through the implementation of a combination of innovative health technologies and practices, it aims to determine the most effective and cost-effective ways of supporting frail older people with long-term conditions to remain well in the community. Among the Test Bed's objectives are to improve patient activation and the ability of older people to self-care at home, reduce healthcare system utilisation, and deliver increased workforce productivity. Patients aged 55 years and over are recruited to four cohorts defined by their risk of hospital admission, with long-term conditions including chronic obstructive pulmonary disease, dementia, diabetes and heart failure. The programme is determined on an individual basis, with a range of technologies available. The evaluation is adopting a two-phase approach: phase 1 includes a bespoke patient survey and a mass matched control analysis; and phase 2 is using observational interviews with patients, and weekly diaries, action learning meetings and focus groups with members of staff and other key stakeholders. Phase 1 data analysis consists of a statistical evaluation of the effectiveness of the programme. A health economic analysis of its costs and associated cost changes will be undertaken. Phase 2 data will be analysed thematically with the aid of Atlas.ti qualitative software. The evaluation is located within a logic model framework, to consider the processes, management and participation that may have implications for the Test Bed's success. The LCIA Test Bed evaluation has received ethical approval from the Health Research Authority and Lancaster University's Faculty of Health and Medicine Research Ethics Committee. A range of dissemination methods are adopted, including deliberative panels to validate findings and develop outcomes for policy

  7. Styrene-spaced copolymers including anthraquinone and β-O-4 lignin model units: synthesis, characterization and reactivity under alkaline pulping conditions.

    Science.gov (United States)

    Megiatto, Jackson D; Cazeils, Emmanuel; Ham-Pichavant, Frédérique; Grelier, Stéphane; Gardrat, Christian; Castellan, Alain

    2012-05-14

    A series of random copoly(styrene)s has been synthesized via radical polymerization of functionalized anthraquinone (AQ) and β-O-4 lignin model monomers. The copolymers were designed to have a different number of styrene spacer groups between the AQ and β-O-4 lignin side chains aiming at investigating the distance effects on AQ/β-O-4 electron transfer mechanisms. A detailed molecular characterization, including techniques such as size exclusion chromatography, MALDI-TOF mass spectrometry, and (1)H, (13)C, (31)P NMR and UV-vis spectroscopies, afforded quantitative information about the composition of the copolymers as well as the average distribution of the AQ and β-O-4 groups in the macromolecular structures. TGA and DSC thermal analysis have indicated that the copolymers were thermally stable under regular pulping conditions, revealing the inertness of the styrene polymer backbone in the investigation of electron transfer mechanisms. Alkaline pulping experiments showed that close contact between the redox active side chains in the copolymers was fundamental for an efficient degradation of the β-O-4 lignin model units, highlighting the importance of electron transfer reactions in the lignin degradation mechanisms catalyzed by AQ. In the absence of glucose, AQ units oxidized phenolic β-O-4 lignin model parts, mainly by electron transfer leading to vanillin as major product. By contrast, in presence of glucose, anthrahydroquinone units (formed by reduction of AQ) reduced the quinone-methide units (issued by dehydration of phenolic β-O-4 lignin model part) mainly by electron transfer leading to guaiacol as major product. Both processes were distance dependent.

  8. Analysis of the unstressed lattice spacing, d0, for the determination of the residual stress in a friction stir welded plate of an age-hardenable aluminum alloy – Use of equilibrium conditions and a genetic algorithm

    International Nuclear Information System (INIS)

    Cioffi, F.; Hidalgo, J.I.; Fernández, R.; Pirling, T.; Fernández, B.; Gesto, D.; Puente Orench, I.; Rey, P.; González-Doncel, G.

    2014-01-01

    Procedures based on equilibrium conditions (stress and bending moment) have been used to obtain an unstressed lattice spacing, d 0 , as a crucial requirement for calculating the residual stress (RS) profile across a joint conducted on a 10 mm thick plate of age-hardenable AA2024 alloy by friction stir welding (FSW). Two procedures have been used that take advantage of neutron diffraction measurements. First, equilibrium conditions were imposed on sections parallel to the weld so that a constant d 0 value corresponding to the base material region could be calculated analytically. Second, balance conditions were imposed on a section transverse to the weld. Then, using the data and a genetic algorithm, suitable d 0 values for the different regions of the weld have been found. For several reasons, the comb method has proved to be inappropriate for RS determination in the case of age-hardenable alloys. However, the equilibrium conditions, together with the genetic algorithm, has been shown to be very suitable for determining RS profiles in FSW joints of these alloys, where inherent microstructural variations of d 0 across the weld are expected

  9. Chemical Engineering in Space

    Science.gov (United States)

    Lobmeyer, Dennis A.; Meneghelli, Barry; Steinrock, Todd (Technical Monitor)

    2001-01-01

    The aerospace industry has long been perceived as the domain of both physicists and mechanical engineers. This perception has endured even though the primary method of providing the thrust necessary to launch a rocket into space is chemical in nature. The chemical engineering and chemistry personnel behind the systems that provide access to space have labored in the shadows of the physicists and mechanical engineers. As exploration into the cosmos moves farther away from Earth, there is a very distinct need for new chemical processes to help provide the means for advanced space exploration. The state of the art in launch systems uses chemical propulsion systems, primarily liquid hydrogen and liquid oxygen, to provide the energy necessary to achieve orbit. As we move away from Earth, there are additional options for propulsion. Unfortunately, few of these options can compare to the speed or ease of use provided by the chemical propulsion agents. It is with great care and significant cost that gaseous compounds such as hydrogen and oxygen are liquefied and become dense enough to use for rocket fuel. These low-temperature liquids fall within a specialty area known as cryogenics. Cryogenics, the science and art of producing cold operating conditions for use on Earth, in orbit, or on some other nonterrestrial body, has become increasingly important to our ability to travel within our solar system. The production of cryogenic fuels and the long-term storage of these fluids are necessary for travel. As our explorations move farther away from Earth, we need to address how to produce the necessary fuels to make a round-trip. The cost and the size of these expeditions are extreme at best. If we take everything necessary for our survival for the round-trip, we invalidate any chance of travel in the near future. As with the early explorers on Earth, we need to harvest much of our energy and our life support from the celestial bodies. The in situ production of these energy

  10. Selected Tether Applications Cost Model

    Science.gov (United States)

    Keeley, Michael G.

    1988-01-01

    Diverse cost-estimating techniques and data combined into single program. Selected Tether Applications Cost Model (STACOM 1.0) is interactive accounting software tool providing means for combining several independent cost-estimating programs into fully-integrated mathematical model capable of assessing costs, analyzing benefits, providing file-handling utilities, and putting out information in text and graphical forms to screen, printer, or plotter. Program based on Lotus 1-2-3, version 2.0. Developed to provide clear, concise traceability and visibility into methodology and rationale for estimating costs and benefits of operations of Space Station tether deployer system.

  11. Space Technospheres

    Science.gov (United States)

    Vidmachenko, A. P.; Steklov, A. F.; Primak, N. V.

    2000-01-01

    Two main tendencies of making the Solar System habitable are regarding nowadays: (1) making objects of the Solar System habitable; and (2) making the space of the Solar System habitable. We think that it's better to combine them. We should dezine and build settlements ('technospheres') on such objects as asteroids and comets, using their resources. That is, it is necessary to create 'space technospheres' - a long-termed human settlements in the space. To save energy resources it is necessary to use Near-Earth asteroids enriched with water ice (i. e. extinguished comets) with Near-Earth orbits. To realize listed conceptions it is necessary to decrease (up to 100 times) the cost price of the long-termed settlements. That's why even average UN country will be able to create it's own space house - artificial planet ('technosphere') and maintain life activities there. About 50-100 such artificial planets will represent the future civilization of our Solar System. At the same time Earth will stay basic, maternal planet. There is an interesting problem of correcting orbits of that objects. Orbits can be changed into circular or elongated to make them comfortable for living activities of 5000-10000 settlers, and to maintain connection with maternal planet. Technospheres with the elongated orbits are more advantageous to assimilate the Solar System. While technospheres with circular orbits suit to the industrial cycle with certain specialization. The specialization of the technosphere will depend on mine-workings and/or chosen high-technology industrial process. Because it is profitable to convert raw materials at the technosphere and then to transport finished products to the maternal planet. It worth to be mentioned that because of the low gravitation and changed life cycle technosphere settlers, new 'Columb' of the Solar System will transform into new mankind. It will happen though it is difficult to imaging this. Because long ago, when fish left the ocean, they didn

  12. Radio-contaminant behaviour in the cover-gas space and the containment building of a sodium-cooled fast reactor in accident conditions

    International Nuclear Information System (INIS)

    Mathe, Emmanuel

    2014-01-01

    experiments chosen in the literature. The mass of oxide aerosols produced by a sodium spray fire can involve more than 60% of the ejected sodium. Then, we develop the numerical simulation STARK based on the Cooper model that model the physico-chemical transformations of the aerosols. However, this model has never been validated and the literature does not permit to do so. In these conditions, we designed and performed our own experiment to obtain the missing values of parameters that govern the Cooper model. The Cooper model has been improved with the results of this experimental study, ESSTIA, and we present a modified Cooper model that improves the accuracy of Cooper model to investigate the transformation of the sodium aerosols. The last part of the manuscript deals with the interaction between sodium aerosols (hydroxide) and a key fission product (iodine). We use density functional theory numerical simulation (the VASP code) to discover the affinities that can be identified. The results will facilitate simulation of the source term evolution because the sodium aerosols will interact with this FP. All the data and numerical simulations presented here will contribute to implementation of models in the future SFR SA numerical simulation of the IRSN, ASTEC-Na. (author)

  13. Teacher Costs

    OpenAIRE

    DINIS MOTA DA COSTA PATRICIA; DE SOUSA LOBO BORGES DE ARAUJO LUISA

    2015-01-01

    The purpose of this technical brief is to assess current methodologies for the collection and calculation of teacher costs in European Union (EU) Member States in view of improving data series and indicators related to teacher salaries and teacher costs. To this end, CRELL compares the Eurydice collection on teacher salaries with the similar Organisation for Economic Co-operation and Development (OECD) data collection and calculates teacher costs based on the methodology established by Statis...

  14. A methodology for costing man-rem

    International Nuclear Information System (INIS)

    Bieber, C.

    1976-03-01

    An attempt is made to provide a methodology for costing man-rem in a way that can be applied to station conditions, based on 1974 Pickering G.S. data. Factors taken into account were social costs, exposure costs (dose accounting, training, dosimetry) temporary labour costs, and permanent replacement labour costs. A figure of $620/ man-rem was derived. (LL)

  15. Operant Conditioning and Education.

    Science.gov (United States)

    de Noronha, Mario

    A case study of a learning disabled 8-year-old with behavior disturbancs is presented to highlight the use of operant conditioning in cutting down educational costs and easing the teacher's class management problems. (CL)

  16. COST QUALITY MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Vitanova Gordana

    2009-05-01

    Full Text Available Within the contemporary economic conditions, enterprises might achieve a competitive advantage if only they sell goods and services with high quality and lower prices. Customers, usually, prefer quality goods with acceptable prices, while such goods create reputation with the particular brand. The perfect control system is necessary to achieve a high quality product, which the cost quality management is considered to be an indispensable part in. The cost quality is nevertheless created to ensure that customers’ requirements are being appropriately attained. The most important objective of quality costs controlling is to assist the management in enhancing the product’s value permanently. The superior cost quality control system helps the management to achieve other strategic objectives, such as: producing goods with acceptable costs and deliver the products to their customers in time.

  17. Cost of mining Eastern coal

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    This paper, Chapter 7.2.3 of the 'surface mining' reference book, gives an example of how the cost of mining a ton of coal is calculated. Conditions set down are for a coal tract of 50.6 ha in West Virginia, USA to be mined by the contour surface method, the seam being 101.6cm thick. Elements of the costing are: permitting and bonding costs, engineering and construction costs, equipment and other operating expenses (such as hauling and wheeling), royalties, direct taxes and fees, costs of revegetation, and employment costs (payroll and medical expenses). 5 tabs

  18. Space station orbit maintenance

    Science.gov (United States)

    Kaplan, D. I.; Jones, R. M.

    1983-01-01

    The orbit maintenance problem is examined for two low-earth-orbiting space station concepts - the large, manned Space Operations Center (SOC) and the smaller, unmanned Science and Applications Space Platform (SASP). Atmospheric drag forces are calculated, and circular orbit altitudes are selected to assure a 90 day decay period in the event of catastrophic propulsion system failure. Several thrusting strategies for orbit maintenance are discussed. Various chemical and electric propulsion systems for orbit maintenance are compared on the basis of propellant resupply requirements, power requirements, Shuttle launch costs, and technology readiness.

  19. Space station operations management

    Science.gov (United States)

    Cannon, Kathleen V.

    1989-01-01

    Space Station Freedom operations management concepts must be responsive to the unique challenges presented by the permanently manned international laboratory. Space Station Freedom will be assembled over a three year period where the operational environment will change as significant capability plateaus are reached. First Element Launch, Man-Tended Capability, and Permanent Manned Capability, represent milestones in operational capability that is increasing toward mature operations capability. Operations management concepts are being developed to accomodate the varying operational capabilities during assembly, as well as the mature operational environment. This paper describes operations management concepts designed to accomodate the uniqueness of Space Station Freedoom, utilizing tools and processes that seek to control operations costs.

  20. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - GIS analysis Franches Montagnes, Switzerland - Documentation of GIS concepts, methods and results

    Energy Technology Data Exchange (ETDEWEB)

    Daellenbach, F.; Schaffner, B. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents part of the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report documents the use of the Geographic Information Systems (GIS) methodology for the 'Franches Montagnes' Region in Switzerland, whereby the most significant of the model's layers was found to be the wind velocity layer.

  1. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Digital relief analysis - Abstract of work package 7

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Cattin, R. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents an abstract of the development work carried out by the Swiss meteorology specialists METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report presents an abstract of the work done as part of the Work Package 7 of the Alpine Windharvest project.

  2. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - CFD modelling evaluation - Summary of WindSim CFD modelling procedure and validation

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Cattin, R. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The report describes the development of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. The report deals with the use of computational fluid dynamics and wind simulation modelling techniques and their validation. Recommendations on the use of the results are made.

  3. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - GIS analysis methodology - Workbook and results

    Energy Technology Data Exchange (ETDEWEB)

    Daellenbach, F.; Schaffner, B. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report presents the development work carried out by the Swiss meteorology specialists of the company METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The report describes the development of basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. The report deals with the use of Geographic Information Systems (GIS) methodology, which includes three steps: the identification of limiting factors for wind power production, the compilation of a GIS layer for each of these factors and, thirdly, their aggregation into a result layer. The methodology was implemented for four case studies in Austria, Italy, Slovenia and Switzerland.

  4. Rehabilitation costs

    Energy Technology Data Exchange (ETDEWEB)

    Kubo, Arthur S [BDM Corp., VA (United States); [Bikini Atoll Rehabilitation Committee, Berkeley, CA (United States)

    1986-07-01

    The costs of radioactivity contamination control and other matters relating to the resettlement of Bikin atoll were reviewed for Bikini Atoll Rehabilitation Committee by a panel of engineers which met in Berkeley, California on January 22-24, 1986. This Appendix presents the cost estimates.

  5. Rehabilitation costs

    International Nuclear Information System (INIS)

    Kubo, Arthur S.

    1986-01-01

    The costs of radioactivity contamination control and other matters relating to the resettlement of Bikin atoll were reviewed for Bikini Atoll Rehabilitation Committee by a panel of engineers which met in Berkeley, California on January 22-24, 1986. This Appendix presents the cost estimates

  6. Cost considerations

    NARCIS (Netherlands)

    Michiel Ras; Debbie Verbeek-Oudijk; Evelien Eggink

    2013-01-01

    Original title: Lasten onder de loep The Dutch government spends almost 7 billion euros  each year on care for people with intellectual disabilities, and these costs are rising steadily. This report analyses what underlies the increase in costs that occurred between 2007 and 2011. Was

  7. Troubleshooting Costs

    Science.gov (United States)

    Kornacki, Jeffrey L.

    Seventy-six million cases of foodborne disease occur each year in the United States alone. Medical and lost productivity costs of the most common pathogens are estimated to be 5.6-9.4 billion. Product recalls, whether from foodborne illness or spoilage, result in added costs to manufacturers in a variety of ways. These may include expenses associated with lawsuits from real or allegedly stricken individuals and lawsuits from shorted customers. Other costs include those associated with efforts involved in finding the source of the contamination and eliminating it and include time when lines are shut down and therefore non-productive, additional non-routine testing, consultant fees, time and personnel required to overhaul the entire food safety system, lost market share to competitors, and the cost associated with redesign of the factory and redesign or acquisition of more hygienic equipment. The cost associated with an effective quality assurance plan is well worth the effort to prevent the situations described.

  8. 12th Reinventing Space Conference

    CERN Document Server

    2017-01-01

    The 2014 Reinventing Space conference presented a number of questions in the context of a constantly innovating space industry, from addressing the future of global cooperation, investigating the impact of cuts in US government spending on the private space sector, and probing the overall future of the commercial launch sector. Space tourism and new technology promise the revival of interest in space development (the Apollo Era was the first period of intense space activity and growth). The need to create dramatically lower cost, responsive and reliable launch systems and spacecraft has never been more vital. Advances in technology are allowing smaller and cheaper satellites to be orbited - from cubesats to nanosatellites to femtosatellites. Thanks to more efficient new launch possibilities, low cost access to space is becoming ever more achievable. Commercial companies and countries are targeting the industry with new funding. Organised by the British Interplanetary Society, the presentations at this confere...

  9. Atoms for space

    Energy Technology Data Exchange (ETDEWEB)

    Buden, D.

    1990-10-01

    Nuclear technology offers many advantages in an expanded solar system space exploration program. These cover a range of possible applications such as power for spacecraft, lunar and planetary surfaces, and electric propulsion; rocket propulsion for lunar and Mars vehicles; space radiation protection; water and sewage treatment; space mining; process heat; medical isotopes; and self-luminous systems. In addition, space offers opportunities to perform scientific research and develop systems that can solve problems here on Earth. These might include fusion and antimatter research, using the Moon as a source of helium-3 fusion fuel, and manufacturing perfect fusion targets. In addition, nuclear technologies can be used to reduce risk and costs of the Space Exploration Initiative. 1 fig.

  10. Atoms for space

    International Nuclear Information System (INIS)

    Buden, D.

    1990-10-01

    Nuclear technology offers many advantages in an expanded solar system space exploration program. These cover a range of possible applications such as power for spacecraft, lunar and planetary surfaces, and electric propulsion; rocket propulsion for lunar and Mars vehicles; space radiation protection; water and sewage treatment; space mining; process heat; medical isotopes; and self-luminous systems. In addition, space offers opportunities to perform scientific research and develop systems that can solve problems here on Earth. These might include fusion and antimatter research, using the Moon as a source of helium-3 fusion fuel, and manufacturing perfect fusion targets. In addition, nuclear technologies can be used to reduce risk and costs of the Space Exploration Initiative. 1 fig

  11. Business Context of Space Tourism

    Science.gov (United States)

    Schmitt, Harrison H.

    2003-01-01

    Broadly speaking, two types of potential commercial activity in space can be defined. First, there are those activities that represent an expansion and improvement on services with broad existing commercial foundations such as telecommunications. The second type of potential commercial activity in space is one that may offer a type of service with few or any existing commercial foundations such as space-based remote sensing. Space tourism clearly belongs in the first category of potential commercial activity in space. Roles in cooperation with the private sector that might be considered for NASA include 1) acceleration of the ``Professional-in Space'' initiative, 2) research and technology developments related to a) a ``Tourist Destination Module'' for the Space Station, b) an ``Extra Passengers Module'' for the payload bay of the Space Shuttle, and c) a ``Passenger-rated Expendable Launch Vehicle,'' 3) definition of criteria for qualifying candidate space tourists, and 4) initiatives to protect space tourism from unreasonable tort litigation. As baseline information for establishing fees, the cost of a possible tourist flight should be fully and objectively delineated. If it is correct that the marginal cost of each Space Shuttle flight to Earth-orbit is about $100 million and the effective Shuttle payload is about 50,000 pounds, then the marginal cost would be roughly $2,000 per pound.

  12. Development of III-V/Si Multijunction Space Photovoltaics

    Data.gov (United States)

    National Aeronautics and Space Administration — High substrate costs, as well as weight, typically play a major role in the high costs of multijunction space solar cell production and deployment. III-V/Si...

  13. Cell genetic processes under space flight conditions: Analysis of two-factor crosses between spore color mutants of Sordaria macrospora. Final report; Zellgenetische Prozesse unter Weltraumbedingungen: Analyse von Zweifaktorenkreuzungen zwischen Sporenfarbenmutanten von Sordaria macrospora. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Hock, B.; Hahn, A.

    2001-07-01

    The purpose of the FUNGUS experiment on S/MM05 was to examine the effects of space flight conditions on the hereditary transmission of the spore color genes. The controls consisted of one further experiment in space with a centrifuge and 1 x g acceleration, and a gravitational reference experiment. A statistical analysis revealed no significant differences attributable to the absence of gravitational effects. A significant increase however was observed in the recombination frequencies, due to the fraction of HZE particles in the cosmic radiation. Gravitational reference experiments showed a dose-dependent effect of heavy-ion particle radiation on the post-reduction frequency and thus on the calculated distances between the genes, higher radiation doses increasing the post-reduction frequency. It was possible to derive dose-response curves for comparison with X-radiation and determination of the RBE of the heavy ion radiation with respect to the calculated distances between the genes 1u and r2. The mycelium of the fungi of the space flight experiment was examined for DNA strand breaks at the molecular level by means of a single cell gel electrophoresis assay. No genetic damage could be detected in the specimens of the experiment in space. Attempts at DNA repair in S. macrospora reveal that most of the damage is healed within a few hours. It was possible to determine the maximum doses of ionizing and non-ionizing radiation up to which DNA repair is possible. (orig./CB) [German] Der Versuch FUNGUS auf S/MM05 hatte zum Ziel, die Auswirkungen der Weltraumbedingungen auf die Vererbung der Farbsporgene zu beobachten. Als Kontrollen dienten eine Zentrifuge, die im Weltraum 1 x g Beschleunigung erzeugte, und ein Bodenreferenzexperiment. Eine statistische Auswertung ergab keine signifikanten Unterschiede, die durch die fehlende Schwerkraft bedingt waren. Eine signifikante Erhoehung der Rekombinationsfrequenzen wird jedoch durch den HZE-Partikelanteil der Weltraumstrahlung

  14. Autonomous Assembly of Structures in Space

    Data.gov (United States)

    National Aeronautics and Space Administration — In-orbit assembly of structures is a task that must be performed by space-walking humans, and yet it is costly, time-consuming, and potentially dangerous. Assembly...

  15. Space weather and space anomalies

    Directory of Open Access Journals (Sweden)

    L. I. Dorman

    2005-11-01

    Full Text Available A large database of anomalies, registered by 220 satellites in different orbits over the period 1971-1994 has been compiled. For the first time, data from 49 Russian Kosmos satellites have been included in a statistical analysis. The database also contains a large set of daily and hourly space weather parameters. A series of statistical analyses made it possible to quantify, for different satellite orbits, space weather conditions on the days characterized by anomaly occurrences. In particular, very intense fluxes (>1000 pfu at energy >10 MeV of solar protons are linked to anomalies registered by satellites in high-altitude (>15000 km, near-polar (inclination >55° orbits typical for navigation satellites, such as those used in the GPS network, NAVSTAR, etc. (the rate of anomalies increases by a factor ~20, and to a much smaller extent to anomalies in geostationary orbits, (they increase by a factor ~4. Direct and indirect connections between anomaly occurrence and geomagnetic perturbations are also discussed.

  16. Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Digital relief analysis - Abstract of work package 7; Alpine Windharvest: development of information base regarding potentials and the necessary technical, legal and socio-economic conditions for expanding wind energy in the Alpine Space - Digitale Relief-Analyse - Zusammenfassung von Arbeitspaket 7

    Energy Technology Data Exchange (ETDEWEB)

    Schaffner, B.; Cattin, R. [Meteotest, Berne (Switzerland)

    2005-07-01

    This report describes the development work carried out by the Swiss meteorology specialists METEOTEST as part of a project carried out together with the Swiss wind-energy organisation 'Suisse Eole'. The framework for the project is the EU Interreg IIIB Alpine Space Programme, a European Community Initiative Programme funded by the European Regional Development Fund. The project investigated the use of digital relief-analysis. The series of reports describes the development and use of a basic information system to aid the investigation of the technical, legal and socio-economical conditions for the use of wind energy in the alpine area. This report presents a summary of work done on the digital relief analysis used in various stages of the project, its validation and use.

  17. Barrelled locally convex spaces

    CERN Document Server

    Pérez Carreras, P

    1987-01-01

    This book is a systematic treatment of barrelled spaces, and of structures in which barrelledness conditions are significant. It is a fairly self-contained study of the structural theory of those spaces, concentrating on the basic phenomena in the theory, and presenting a variety of functional-analytic techniques.Beginning with some basic and important results in different branches of Analysis, the volume deals with Baire spaces, presents a variety of techniques, and gives the necessary definitions, exploring conditions on discs to ensure that they are absorbed by the barrels of the sp

  18. Neighborhood spaces

    OpenAIRE

    D. C. Kent; Won Keun Min

    2002-01-01

    Neighborhood spaces, pretopological spaces, and closure spaces are topological space generalizations which can be characterized by means of their associated interior (or closure) operators. The category NBD of neighborhood spaces and continuous maps contains PRTOP as a bicoreflective subcategory and CLS as a bireflective subcategory, whereas TOP is bireflectively embedded in PRTOP and bicoreflectively embedded in CLS. Initial and final structures are described in these categories, and it is s...

  19. Universal Space IP Transparent Proxy, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Communications applications are strategically moving toward Internet Protocol-based architectures and technologies. Despite IP's huge potential, (e.g. cost...

  20. Challenges for future space power systems

    International Nuclear Information System (INIS)

    Brandhorst, H.W. Jr.

    1989-01-01

    Forecasts of space power needs are presented. The needs fall into three broad categories: survival, self-sufficiency, and industrialization. The cost of delivering payloads to orbital locations and from Low Earth Orbit (LEO) to Mars are determined. Future launch cost reductions are predicted. From these projections the performances necessary for future solar and nuclear space power options are identified. The availability of plentiful cost effective electric power and of low cost access to space are identified as crucial factors in the future extension of human presence in space