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Sample records for space biosensor technology

  1. Medical and surgical applications of space biosensor technology

    Hines, J. W.

    1996-01-01

    Researchers in space life sciences are rapidly approaching a technology impasse. Many of the critical questions on the impact of spaceflight on living systems simply cannot be answered with the limited available technologies. Research subjects, particularly small animal models like the rat, must be allowed to function relatively untended and unrestrained for long periods to fully reflect the impact of microgravity and spaceflight on their behavior and physiology. These requirements preclude the use of present hard-wired instrumentation techniques and limited data acquisition systems. Implantable sensors and miniaturized biotelemetry are the only means of capturing the fundamental and critical data. This same biosensor and biotelemetry technology has direct application to Earth-based medicine and surgery. Continuous, on-line data acquisition and improved measurement capabilities combined with the ease and flexibility offered by automated, wireless, and portable instruments and data systems, should provide a boon to the health care industry. Playing a key role in this technology revolution is the Sensors 2000! (S2K!) Program at NASA Ames Research Center. S2K!, in collaboration with space life sciences researchers and managers, provides an integrated capability for sensor technology development and applications, including advanced biosensor technology development, spaceflight hardware development, and technology transfer and commercialization. S2K! is presently collaborating on several spaceflight projects with dual-use medical applications. One prime example is a collaboration with the Fetal Treatment Center (FTC) at the University of California at San Francisco. The goal is to develop and apply implantable chemical sensor and biotelemetry technology to continuously monitor fetal patients during extra-uterine surgery, replacement into the womb, through birth and beyond. Once validated for ground use, the method will be transitioned to spaceflight applications to

  2. Medical and surgical applications of space biosensor technology

    Hines, John W.

    1996-02-01

    Researchers in space life sciences are rapidly approaching a technology impasse. Many of the critical questions on the impact of spaceflight on living systems simply cannot be answered with the limited available technologies. Research subjects, particularly small animal models like the rat, must be allowed to function relatively untended and unrestrained for long periods to fully reflect the impact of microgravity and spaceflight on their behavior and physiology. These requirements preclude the use of present hard-wired instrumentation techniques and limited data acquisition systems. Implantable sensors and miniaturized biotelemetry are the only means of capturing the fundamental and critical data. This same biosensor and biotelemetry technology has direct application to Earth-based medicine and surgery. Continuous, on-line data acquisition and improved measurement capabilities combined with the ease and flexibility offered by automated, wireless, and portable instruments and data systems, should provide a boon to the health care industry. Playing a key role in this technology revolution is the Sensors 2000! (S2K!) Program at NASA Ames Research Center. S2K!, in collaboration with space life sciences researchers and managers, provides an integrated capability for sensor technology development and applications, including advanced biosensor technology development, spaceflight hardware development, and technology transfer and commercialization. S2K! is presently collaborating on several spaceflight projects with dual-use medical applications. One prime example is a collaboration with the Fetal Treatment Center (FTC) at the University of California at San Francisco. The goal is to develop and apply implantable chemical sensor and biotelemetry technology to continuously monitor fetal patients during extra-uterine surgery, replacement into the womb, through birth and beyond. Once validated for ground use, the method will be transitioned to spaceflight applications to

  3. Biosensor technology for pesticides--a review.

    Verma, Neelam; Bhardwaj, Atul

    2015-03-01

    Pesticides, due to their lucrative outcomes, are majorly implicated in agricultural fields for crop production enhancement. Due to their pest removal properties, pesticides of various classes have been designed to persist in the environment over a longer duration after their application to achieve maximum effectiveness. Apart from their recalcitrant structure and agricultural benefits, pesticides also impose acute toxicological effects onto the other various life forms. Their accumulation in the living system may prove to be detrimental if established in higher concentrations. Thus, their prompt and accurate analysis is a crucial matter of concern. Conventional techniques like chromatographic techniques (HPLC, GC, etc.) used for pesticides detection are associated with various limitations like stumpy sensitivity and efficiency, time consumption, laboriousity, requirement of expensive equipments and highly trained technicians, and many more. So there is a need to recruit the methods which can detect these neurotoxic compounds sensitively, selectively, rapidly, and easily in the field. Present work is a brief review of the pesticide effects, their current usage scenario, permissible limits in various food stuffs and 21st century advancements of biosensor technology for pesticide detection. Due to their exceptional performance capabilities, easiness in operation and on-site working, numerous biosensors have been developed for bio-monitoring of various environmental samples for pesticide evaluation immensely throughout the globe. Till date, based on sensing element (enzyme based, antibody based, etc.) and type of detection method used (Electrochemical, optical, and piezoelectric, etc.), a number of biosensors have been developed for pesticide detection. In present communication, authors have summarized 21st century's approaches of biosensor technology for pesticide detection such as enzyme-based biosensors, immunosensors, aptamers, molecularly imprinted polymers, and

  4. Nano technologies for Biosensor and Bio chip

    Kim, I.M.; Park, T.J.; Paskaleva, E.E.; Sun, F.; Seo, J.W.; Mehta, K.K.

    2015-01-01

    The bio sensing devices are characterized by their biological receptors, which have specificity to their corresponding analytes. These analytes are a vast and diverse group of biological molecules, DNAs, proteins (such as antibodies), fatty acids, or entire biological systems, such as pathogenic bacteria, viruses, cancerous cells, or other living organisms. A main challenge in the development of biosensor applications is the efficient recognition of a biological signal in a low signal-to-noise ratio environment, and its transduction into an electrochemical, optical, or other signals. The advent of nano material technology greatly increased the potential for achieving exquisite sensitivity of such devises, due to the innate high surface-to-volume ratio and high reactivity of the nano material. The second major challenge facing the biosensor application, that of sca lability, is addressed by multiplexing and miniaturizing of the biosensor devises into a bio chip. In recent years, biosensor and bio chip technologies have made significant progress by taking advantages of diverse kinds of nano materials that are derived from nano technology

  5. Biosensors in the small scale: methods and technology trends.

    Senveli, Sukru U; Tigli, Onur

    2013-03-01

    This study presents a review on biosensors with an emphasis on recent developments in the field. A brief history accompanied by a detailed description of the biosensor concepts is followed by rising trends observed in contemporary micro- and nanoscale biosensors. Performance metrics to quantify and compare different detection mechanisms are presented. A comprehensive analysis on various types and subtypes of biosensors are given. The fields of interest within the scope of this review are label-free electrical, mechanical and optical biosensors as well as other emerging and popular technologies. Especially, the latter half of the last decade is reviewed for the types, methods and results of the most prominently researched detection mechanisms. Tables are provided for comparison of various competing technologies in the literature. The conclusion part summarises the noteworthy advantages and disadvantages of all biosensors reviewed in this study. Furthermore, future directions that the micro- and nanoscale biosensing technologies are expected to take are provided along with the immediate outlook.

  6. Biosensors.

    Rechnitz, Garry A.

    1988-01-01

    Describes theory and principles behind biosensors that incorporate biological components as part of a sensor or probe. Projects major applications in medicine and veterinary medicine, biotechnology, food and agriculture, environmental studies, and the military. Surveys current use of biosensors. (ML)

  7. BioSentinel: Developing a Space Radiation Biosensor

    Santa Maria, Sergio R.

    2015-01-01

    BioSentinel is an autonomous fully self-contained science mission that will conduct the first study of the biological response to space radiation outside low Earth orbit (LEO) in over 40 years. The 4-unit (4U) BioSentinel biosensor system, is housed within a 6-Unit (6U) spacecraft, and uses yeast cells in multiple independent microfluidic cards to detect and measure DNA damage that occurs in response to ambient space radiation. Cell growth and metabolic activity will be measured using a 3-color LED detection system and a metabolic indicator dye with a dedicated thermal control system per fluidic card.

  8. Utilization of biosensors and chemical sensors for space applications

    Bonting, S. L.

    1992-01-01

    There will be a need for a wide array of chemical sensors for biomedical experimentation and for the monitoring of water and air recycling processes on Space Station Freedom. The infrequent logistics flights of the Space Shuttle will necessitate onboard analysis. The advantages of biosensors and chemical sensors over conventional analysis onboard spacecraft are manifold. They require less crew time, space, and power. Sample treatment is not needed. Real time or near-real time monitoring is possible, in some cases on a continuous basis. Sensor signals in digitized form can be transmitted to the ground. Types and requirements for chemical sensors to be used in biomedical experimentation and monitoring of water recycling during long-term space missions are discussed.

  9. BioSentinel: Biosensors for Deep-Space Radiation Study

    Lokugamage, Melissa P.; Santa Maria, Sergio R.; Marina, Diana B.; Bhattacharya, Sharmila

    2016-01-01

    The BioSentinel mission will be deployed on NASA's Exploration Mission 1 (EM-1) in 2018. We will use the budding yeast, Saccharomyces cerevisiae, as a biosensor to study the effect of deep-space radiation on living cells. The BioSentinel mission will be the first investigation of a biological response to space radiation outside Low Earth Orbit (LEO) in over 40 years. Radiation can cause damage such as double stand breaks (DSBs) on DNA. The yeast cell was chosen for this mission because it is genetically controllable, shares homology with human cells in its DNA repair pathways, and can be stored in a desiccated state for long durations. Three yeast strains will be stored dry in multiple microfluidic cards: a wild type control strain, a mutant defective strain that cannot repair DSBs, and a biosensor strain that can only grow if it gets DSB-and-repair events occurring near a specific gene. Growth and metabolic activity of each strain will be measured by a 3-color LED optical detection system. Parallel experiments will be done on the International Space Station and on Earth so that we can compare the results to that of deep space. One of our main objectives is to characterize the microfluidic card activation sequence before the mission. To increase the sensitivity of yeast cells as biosensors, desiccated yeast in each card will be resuspended in a rehydration buffer. After several weeks, the rehydration buffer will be exchanged with a growth medium in order to measure yeast growth and metabolic activity. We are currently working on a time-course experiment to better understand the effects of the rehydration buffer on the response to ionizing radiation. We will resuspend the dried yeast in our rehydration medium over a period of time; then each week, we will measure the viability and ionizing radiation sensitivity of different yeast strains taken from this rehydration buffer. The data obtained in this study will be useful in finalizing the card activation sequence for

  10. G-Protein Coupled Receptors: Surface Display and Biosensor Technology

    McMurchie, Edward; Leifert, Wayne

    Signal transduction by G-protein coupled receptors (GPCRs) underpins a multitude of physiological processes. Ligand recognition by the receptor leads to the activation of a generic molecular switch involving heterotrimeric G-proteins and guanine nucleotides. With growing interest and commercial investment in GPCRs in areas such as drug targets, orphan receptors, high-throughput screening of drugs and biosensors, greater attention will focus on assay development to allow for miniaturization, ultrahigh-throughput and, eventually, microarray/biochip assay formats that will require nanotechnology-based approaches. Stable, robust, cell-free signaling assemblies comprising receptor and appropriate molecular switching components will form the basis of future GPCR/G-protein platforms, which should be able to be adapted to such applications as microarrays and biosensors. This chapter focuses on cell-free GPCR assay nanotechnologies and describes some molecular biological approaches for the construction of more sophisticated, surface-immobilized, homogeneous, functional GPCR sensors. The latter points should greatly extend the range of applications to which technologies based on GPCRs could be applied.

  11. Genomic and Phenotypic Characterization of Yeast Biosensor for Deep-space Radiation

    Marina, Diana B.; Santa Maria, Sergio; Bhattacharya, Sharmila

    2016-01-01

    The BioSentinel mission was selected to launch as a secondary payload onboard NASA Exploration Mission 1 (EM-1) in 2018. In BioSentinel, the budding yeast Saccharomyces cerevisiae will be used as a biosensor to measure the long-term impact of deep-space radiation to living organisms. In the 4U-payload, desiccated yeast cells from different strains will be stored inside microfluidic cards equipped with 3-color LED optical detection system to monitor cell growth and metabolic activity. At different times throughout the 12-month mission, these cards will be filled with liquid yeast growth media to rehydrate and grow the desiccated cells. The growth and metabolic rates of wild-type and radiation-sensitive strains in deep-space radiation environment will be compared to the rates measured in the ground- and microgravity-control units. These rates will also be correlated with measurements obtained from onboard physical dosimeters. In our preliminary long-term desiccation study, we found that air-drying yeast cells in 10% trehalose is the best method of cell preservation in order to survive the entire 18-month mission duration (6-month pre-launch plus 12-month full-mission periods). However, our study also revealed that desiccated yeast cells have decreasing viability over time when stored in payload-like environment. This suggests that the yeast biosensor will have different population of cells at different time points during the long-term mission. In this study, we are characterizing genomic and phenotypic changes in our yeast biosensor due to long-term storage and desiccation. For each yeast strain that will be part of the biosensor, several clones were reisolated after long-term storage by desiccation. These clones were compared to their respective original isolate in terms of genomic composition, desiccation tolerance and radiation sensitivity. Interestingly, clones from a radiation-sensitive mutant have better desiccation tolerance compared to their original isolate

  12. Inkjet printing for biosensor fabrication: combining chemistry and technology for advanced manufacturing.

    Li, Jia; Rossignol, Fabrice; Macdonald, Joanne

    2015-06-21

    Inkjet printing is emerging at the forefront of biosensor fabrication technologies. Parallel advances in both ink chemistry and printers have led to a biosensor manufacturing approach that is simple, rapid, flexible, high resolution, low cost, efficient for mass production, and extends the capabilities of devices beyond other manufacturing technologies. Here we review for the first time the factors behind successful inkjet biosensor fabrication, including printers, inks, patterning methods, and matrix types. We discuss technical considerations that are important when moving beyond theoretical knowledge to practical implementation. We also highlight significant advances in biosensor functionality that have been realised through inkjet printing. Finally, we consider future possibilities for biosensors enabled by this novel combination of chemistry and technology.

  13. Carbon Nanotube Biosensors for Space Molecule Detection and Clinical Molecular Diagnostics

    Han, Jie

    2001-01-01

    Both space molecule detection and clinical molecule diagnostics need to develop ultra sensitive biosensors for detection of less than attomole molecules such as amino acids for DNA. However all the electrode sensor systems including those fabricated from the existing carbon nanotubes, have a background level of nA (nanoAmp). This has limited DNA or other molecule detection to nA level or molecules whose concentration is, much higher than attomole level. A program has been created by NASA and NCI (National Cancer Institute) to exploit the possibility of carbon nanotube based biosensors to solve this problem for both's interest. In this talk, I will present our effort on the evaluation and novel design of carbon nanotubes as electrode biosensors with strategies to minimize background currents while maximizing signal intensity.The fabrication of nanotube electrode arrays, immobilization of molecular probes on nanotube electrodes and in vitro biosensor testing will also be discussed.

  14. A Study of Wearable Bio-Sensor Technologies and Applications in Healthcare

    Amir Mehmood

    2017-06-01

    Full Text Available In today’s world the rapid advancements in Micro-Electromechanical Systems (MEMS and Nano technology have improved almost all the aspects of daily life routine with the help of different smart devices such as smart phones, compact electronic devices etc. The prime example of these emerging developments is the development of wireless sensors for healthcare procedures. One kind of these sensors is wearable bio-sensors. In this paper, the technologies of two types of bio-sensors (ECG, EMG are investigated and also compared with traditional ECG, EMG equipment. We have taken SHIMMERTM wireless sensor platform as an example of wearable biosensors technology. We have investigated the systems developed for analysis techniques with SHIMMERTM ECG and EMG wearable bio-sensors and these biosensors are used in continuous remote monitoring. For example, applications in continuous health monitoring of elderly people, critical chronic patients and Fitness & Fatigue observations. Nevertheless, early fall detection in older adults and weak patients, treatment efficacy assessment. This study not only provides the basic concepts of wearable wireless bio-sensors networks (WBSN, but also provides basic knowledge of different sensor platforms available for patient’s remote monitoring. Also various healthcare applications by using bio-sensors are discussed and in last comparison with traditional ECG and EMG is presented.

  15. Smart space technology innovations

    Chen, Mu-Yen

    2013-01-01

    Recently, ad hoc and wireless communication technologies have made available the device, service and information rich environment for users. Smart Space and ubiquitous computing extend the ""Living Lab"" vision of everyday objects and provide context-awareness services to users in smart living environments. This ebook investigates smart space technology and its innovations around the Living Labs. The final goal is to build context-awareness smart space and location-based service applications that integrate information from independent systems which autonomously and securely support human activ

  16. Advanced biosensors for monitoring astronauts' health during long-duration space missions.

    Roda, Aldo; Mirasoli, Mara; Guardigli, Massimo; Zangheri, Martina; Caliceti, Cristiana; Calabria, Donato; Simoni, Patrizia

    2018-07-15

    Long-duration space missions pose important health concerns for astronauts, especially regarding the adverse effects of microgravity and exposure to high-energy cosmic rays. The long-term maintenance of crew health and performance mainly relies on prevention, early diagnoses, condition management, and medical interventions in situ. In-flight biosensor diagnostic devices and medical procedures must use few resources and operate in a microgravity environment, which complicates the collection and management of biological samples. Moreover, the biosensors must be certified for in-flight operation according to strict design and safety regulations. Herein, we report on the state of the art and recent advances in biosensing diagnostic instrumentation for monitoring astronauts' health during long-duration space missions, including portable and wearable biosensors. We discuss perspectives on new-format biosensors in autonomous space clinics. We also describe our own work in developing biosensing devices for non-invasively diagnosing space-related diseases, and how they are used in long-duration missions. Finally, we discuss the benefits of space exploration for Earth-based medicine. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. Dual Space Technology Transfer

    Kowbel, W.; Loutfy, R.

    2009-03-01

    Over the past fifteen years, MER has had several NASA SBIR Phase II programs in the area of space technology, based upon carbon-carbon (C-C) composites. In addition, in November 2004, leading edges supplied by MER provided the enabling technology to reach a Mach 10 record for an air breathing engine on the X-43 A flight. The MER business model constitutes a spin-off of technologies initially by incubating in house, and ultimately creating spin-off stand alone companies. FMC was formed to provide for technology transfer in the area of fabrication of C-C composites. FMC has acquired ISO 9000 and AS9100 quality certifications. FMC is fabricating under AS9100 certification, flight parts for several flight programs. In addition, FMC is expanding the application of carbon-carbon composites to several critical military programs. In addition to space technology transfer to critical military programs, FMC is becoming the world leader in the commercial area of low-cost C-C composites for furnace fixtures. Market penetrations have been accomplished in North America, Europe and Asia. Low-cost, quick turn-around and excellent quality of FMC products paves the way to greatly increased sales. In addition, FMC is actively pursuing a joint venture with a new partner, near closure, to become the leading supplier of high temperature carbon based composites. In addition, several other spin-off companies such as TMC, FiC, Li-Tech and NMIC were formed by MER with a plethora of potential space applications.

  18. Biosensors for Real-Time Monitoring of Radiation-Induced Biologic Effects in Space

    Baker, James R.; Balogh, Lajos; Majoros, Istvan; Keszler, Balazs; Myc, Andrzej; Kukowska-Latallo, Jolanta; Norris, Theodore; delaiglesia, Felix; Beeson, Nicholas W. (Compiler)

    2002-01-01

    This work seeks to develop cellular biosensors based on dendritic polymers. Nanoscale polymer structures less than 20 nm in diameter will be used as the basis of the biosensors. The structures will be designed to target into specific cells of an astronaut and be able to monitor health issues such as exposure to radiation. Multiple components can be assembled on the polymers including target directors, analytical devices (such as molecular probes), and reporting agents. The reporting will be accomplished through fluorescence signal monitoring, with the use of multispectral analysis for signal interpretation. These nanosensors could facilitate the success and increase the safety of extended space flight. The design and assembly of these devices has been pioneered at the Center for Biologic Nanotechnology in the University of Michigan. This period, synthesis of the test-bed biosensors continued. Studies were performed on the candidate fluorescent dyes to determine which might be suitable for the biosensor under development. Development continued on producing an artificial capillary bed as a tool for the use in the production of the fluorescence signal monitor. Work was also done on the in vitro multispectral analysis system, which uses the robotic microscope.

  19. Disruptive Space Technology

    Benson, Jim

    2004-01-01

    In 1997 "The Innovator’s Dilemma" by Clayton M. Christensen became a popular book in the small satellite and launch vehicle communities. But like the weather, every one talks about “Disruptive Technology” but few do anything about it. In the ‘70s and ‘80s, people were looking for “Paradigm Shifts,” and since the resurrection of Donald Rumsfeld, a recent watchword has been “Transformational Technology.” But today’s buzzword is now “Responsive Space Systems.”

  20. Building Better Biosensors for Exploration into Deep-Space, Using Humanized Yeast

    Liddell, Lauren; Santa Maria, Sergio; Tieze, Sofia; Bhattacharya, Sharmila

    2017-01-01

    1.BioSentinel is 1 of 13 secondary payloads hitching a ride beyond Low Earth Orbit on Exploration Mission 1 (EM-1), set to launch from NASAs Space Launch System in 2019. EM-1 is our first opportunity to investigate the effects of the deep space environment on a eukaryotic biological system, the budding yeast S. cerevisiae. Though separated by a billion years of evolution we share hundreds of genes important for basic cell function, including responses to DNA damage. Thus, yeast is an ideal biosensor for detecting typesextent of damage induced by deep-space radiation.We will fly desiccated cells, then rehydrate to wake them up when the automated payload is ready to initiate the experiment. Rehydration solution contains SC (Synthetic Complete) media and alamarBlue, an indicator for changes in growth and metabolism. Telemetry of LED readings will then allow us to detect how cells respond throughout the mission. The desiccation-rehydration process can be extremely damaging to cells, and can severely diminish our ability to accurately measure and model cellular responses to deep-space radiation. The aim of this study is to develop a better biosensor: yeast strains that are more resistant to desiccation stress. We will over-express known cellular protectants, including hydrophilin Sip18, the protein disaggregase Hsp104, and thioredoxin Trx2, a responder to oxidative stress, then measure cell viability after desiccation to determine which factors improve stress tolerance. Over-expression of SIP18 in wine yeast starter cultures was previously reported to increase viability following desiccation stress by up to 70. Thus, we expect similar improvements in our space-yeast strains. By designing better yeast biosensors we can better prepare for and mitigate the potential dangers of deep-space radiation for future missions.This work is funded by NASAs AES program.

  1. How cutting-edge technologies impact the design of electrochemical (bio)sensors for environmental analysis. A review.

    Arduini, Fabiana; Cinti, Stefano; Scognamiglio, Viviana; Moscone, Danila; Palleschi, Giuseppe

    2017-03-22

    Through the years, scientists have developed cutting-edge technologies to make (bio)sensors more convenient for environmental analytical purposes. Technological advancements in the fields of material science, rational design, microfluidics, and sensor printing, have radically shaped biosensor technology, which is even more evident in the continuous development of sensing systems for the monitoring of hazardous chemicals. These efforts will be crucial in solving some of the problems constraining biosensors to reach real environmental applications, such as continuous analyses in field by means of multi-analyte portable devices. This review (with 203 refs.) covers the progress between 2010 and 2015 in the field of technologies enabling biosensor applications in environmental analysis, including i) printing technology, ii) nanomaterial technology, iii) nanomotors, iv) biomimetic design, and (v) microfluidics. Next section describes futuristic cutting-edge technologies that are gaining momentum in recent years, which furnish highly innovative aspects to biosensing devices. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Technological Spaces: An Initial Appraisal

    Ivanov, Ivan; Bézivin, Jean; Aksit, Mehmet

    2002-01-01

    In this paper, we propose a high level view of technological spaces (TS) and relations among these spaces. A technological space is a working context with a set of associated concepts, body of knowledge, tools, required skills, and possibilities. It is often associated to a given user community with

  3. Synthetic biology and biomimetic chemistry as converging technologies fostering a new generation of smart biosensors.

    Scognamiglio, Viviana; Antonacci, Amina; Lambreva, Maya D; Litescu, Simona C; Rea, Giuseppina

    2015-12-15

    Biosensors are powerful tunable systems able to switch between an ON/OFF status in response to an external stimulus. This extraordinary property could be engineered by adopting synthetic biology or biomimetic chemistry to obtain tailor-made biosensors having the desired requirements of robustness, sensitivity and detection range. Recent advances in both disciplines, in fact, allow to re-design the configuration of the sensing elements - either by modifying toggle switches and gene networks, or by producing synthetic entities mimicking key properties of natural molecules. The present review considered the role of synthetic biology in sustaining biosensor technology, reporting examples from the literature and reflecting on the features that make it a useful tool for designing and constructing engineered biological systems for sensing application. Besides, a section dedicated to bioinspired synthetic molecules as powerful tools to enhance biosensor potential is reported, and treated as an extension of the concept of biomimetic chemistry, where organic synthesis is used to generate artificial molecules that mimic natural molecules. Thus, the design of synthetic molecules, such as aptamers, biomimetics, molecular imprinting polymers, peptide nucleic acids, and ribozymes were encompassed as "products" of biomimetic chemistry. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Multiplexed lateral flow biosensors: Technological advances for radically improving point-of-care diagnoses.

    Li, Jia; Macdonald, Joanne

    2016-09-15

    Lateral flow biosensors are a leading technology in point-of-care diagnostics due to their simplicity, rapidness and low cost. Their primacy in this arena continues through technological breakthroughs such as multiplexing: the detection of more than one biomarker in a single assay. Multiplexing capacity is critical for improving diagnostic efficiency, enhancing the diagnostic precision for specific diseases and reducing diagnostic cost. Here we review, for the first time, the various types and strategies employed for creating multiplexed lateral flow biosensors. These are classified into four main categories in terms of specific application or multiplexing level, namely linear, parameter, spatial and conceptual. We describe the practical applications and implications for each approach and compare their advantages and disadvantages. Importantly, multiplexing is still subject to limitations of the traditional lateral flow biosensor, such as sensitivity and specificity. However, by pushing the limitations of the traditional medium into the multiplex arena, several technological breakthroughs are emerging with novel solutions that further expand the utility of lateral flow biosensing for point-of-care applications. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Food technology in space habitats

    Karel, M.

    1979-01-01

    The research required to develop a system that will provide for acceptable, nutritious, and safe diets for man during extended space missions is discussed. The development of a food technology system for space habitats capable of converting raw materials produced in the space habitats into acceptable food is examined.

  6. Identification of Novel Desiccation-Tolerant S. cerevisiae Strains for Deep Space Biosensors

    Tieze, Sofia Massaro; Santa Maria, Sergio R.; Liddell, Lauren; Bhattacharya, Sharmila

    2017-01-01

    NASA's BioSentinel mission, a secondary payload that will fly on the Space Launch Systems first Exploration Mission (EM-1), utilizes the budding yeast S. cerevisiae to study the biological response to the deep space radiation environment. Yeast samples are desiccated prior to launch to suspend growth and metabolism while the spacecraft travels to its target heliocentric orbit beyond Low Earth Orbit. Each sample is then rehydrated at the desired time points to reactivate the cells. A major risk in this mission is the loss of cell viability that occurs in the recovery period following the desiccation and rehydration process. Cell survival is essential for the detection of the biological response to features in the deep space environment, including ionizing radiation.The aim of this study is to mitigate viable cell loss in future biosensors by identifying mutations and genes that confer tolerance to desiccation stress in rad51, a radiation-sensitive yeast strain. We initiated a screen for desiccation-tolerance after rehydrating cells that were desiccated for three years, and selected various clones exhibiting robust growth. To verify retention of radiation sensitivity in the isolated clonesa crucial feature for a successful biosensorwe exposed them to ionizing radiation. Finally, to elucidate the genetic and molecular bases for observed desiccation-tolerance, we will perform whole-genome sequencing of those rad51 clones that exhibit both robust growth and radiation sensitivity following desiccation. The identification and characterization of desiccation-tolerant strains will allow us to engineer a biological model that will be resilient in face of the challenges of the deep space environment, and will thus ensure the experimental success of future biosensor missions.

  7. A technology roadmap of smart biosensors from conventional glucose monitoring systems.

    Shende, Pravin; Sahu, Pratiksha; Gaud, Ram

    2017-06-01

    The objective of this review article is to focus on technology roadmap of smart biosensors from a conventional glucose monitoring system. The estimation of glucose with commercially available devices involves analysis of blood samples that are obtained by pricking finger or extracting blood from the forearm. Since pain and discomfort are associated with invasive methods, the non-invasive measurement techniques have been investigated. The non-invasive methods show advantages like non-exposure to sharp objects such as needles and syringes, due to which there is an increase in testing frequency, improved control of glucose concentration and absence of pain and biohazard materials. This review study is aimed to describe recent invasive techniques and major noninvasive techniques, viz. biosensors, optical techniques and sensor-embedded contact lenses for glucose estimation.

  8. Advancing Porous Silicon Biosensor Technology for Use in Clinical Diagnostics

    Bonanno, Lisa Marie

    Inexpensive and robust analytical techniques for detecting molecular recognition events are in great demand in healthcare, food safety, and environmental monitoring. Despite vast research in this area, challanges remain to develop practical biomolecular platforms that, meet the rigorous demands of real-world applications. This includes maintaining low-cost devices that are sensitive and specific in complex test specimens, are stable after storage, have short assay time, and possess minimal complexity of instrumentation for readout. Nanostructured porous silicon (PSi) material has been identified as an ideal candidate towards achieving these goals and the past decade has seen diverse proof-of-principle studies developing optical-based sensing techniques. In Part 1 of this thesis, the impact of surface chemistry and PSi morphology on detection sensitivity of target molecules is investigated. Initial proof-of-concept that PSi devices facilitate detection of protein in whole blood is demonstrated. This work highlights the importance of material stability and blocking chemistry for sensor use in real world biological samples. In addition, the intrinisic filtering capability of the 3-D PSi morphology is shown as an advantage in complex solutions, such as whole blood. Ultimately, this initial work identified a need to improve detection sensitivity of the PSI biosensor technique to facilitate clinical diagnostic use over relevant target concentration ranges. The second part of this thesis, builds upon sensitivity challenges that are highlighted in the first part of the thesis and development of a surface-bound competitive inhibition immunoassay facilitated improved detection sensitivity of small molecular weight targets (opiates) over a relevant clinical concentration range. In addition, optimization of assay protocol addressed issues of maintaining stability of sensors after storage. Performance of the developed assay (specificity and sensitivity) was then validated in a

  9. BIOSENSOR TECHNOLOGY EVALUATIONS FOR REAL-TIME/SOURCE WATER PROTECTION

    Recent advances in electronics and computer technology have made great strides in the field of remote sensing and biomonitoring. The quality of drinking water sources has come under closer scrutiny in recent years. Issues ranging from ecological to public health and national se...

  10. NASA Space Laser Technology

    Krainak, Michael A.

    2015-01-01

    Over the next two decades, the number of space based laser missions for mapping, spectroscopy, remote sensing and other scientific investigations will increase several fold. The demand for high wall-plug efficiency, low noise, narrow linewidth laser systems to meet different systems requirements that can reliably operate over the life of a mission will be high. The general trends will be for spatial quality very close to the diffraction limit, improved spectral performance, increased wall-plug efficiency and multi-beam processing. Improved spectral performance will include narrower spectral width (very near the transform limit), increased wavelength stability and or tuning (depending on application) and lasers reaching a wider range of wavelengths stretching into the mid-infrared and the near ultraviolet. We are actively developing high efficiency laser transmitter and high-sensitivity laser receiver systems that are suitable for spaceborne applications.

  11. Plasmonic biosensors.

    Hill, Ryan T

    2015-01-01

    The unique optical properties of plasmon resonant nanostructures enable exploration of nanoscale environments using relatively simple optical characterization techniques. For this reason, the field of plasmonics continues to garner the attention of the biosensing community. Biosensors based on propagating surface plasmon resonances (SPRs) in films are the most well-recognized plasmonic biosensors, but there is great potential for the new, developing technologies to surpass the robustness and popularity of film-based SPR sensing. This review surveys the current plasmonic biosensor landscape with emphasis on the basic operating principles of each plasmonic sensing technique and the practical considerations when developing a sensing platform with the various techniques. The 'gold standard' film SPR technique is reviewed briefly, but special emphasis is devoted to the up-and-coming localized surface plasmon resonance and plasmonically coupled sensor technology. © 2014 Wiley Periodicals, Inc.

  12. Commercial Space with Technology Maturation

    McCleskey, Carey M.; Rhodes, Russell E.; Robinson, John W.

    2013-01-01

    To provide affordable space transportation we must be capable of using common fixed assets and the infrastructure for multiple purposes simultaneously. The Space Shuttle was operated for thirty years, but was not able to establish an effective continuous improvement program because of the high risk to the crew on every mission. An unmanned capability is needed to provide an acceptable risk to the primary mission. This paper is intended to present a case where a commercial space venture could share the large fixed cost of operating the infrastructure with the government while the government provides new advanced technology that is focused on reduced operating cost to the common launch transportation system. A conceivable commercial space venture could provide educational entertainment for the country's youth that would stimulate their interest in the science, technology, engineering, and mathematics (STEM) through access at entertainment parks or the existing Space Visitor Centers. The paper uses this example to demonstrate how growing public-private space market demand will re-orient space transportation industry priorities in flight and ground system design and technology development, and how the infrastructure is used and shared.

  13. Space weapon technology and policy

    Hitchens, Theresa

    2017-11-01

    The military use of space, including in support of nuclear weapons infrastructure, has greatly increased over the past 30 years. In the current era, rising geopolitical tensions between the United States and Russia and China have led to assumptions in all three major space powers that warfighting in space now is inevitable, and possible because of rapid technological advancements. New capabilities for disrupting and destroying satellites include radio-frequency jamming, the use of lasers, maneuverable space objects and more capable direct-ascent anti-satellite weapons. This situation, however, threatens international security and stability among nuclear powers. There is a continuing and necessary role for diplomacy, especially the establishment of normative rules of behavior, to reduce risks of misperceptions and crisis escalation, including up to the use of nuclear weapons. U.S. policy and strategy should seek a balance between traditional military approaches to protecting its space assets and diplomatic tools to create a more secure space environment.

  14. High-efficient and high-content cytotoxic recording via dynamic and continuous cell-based impedance biosensor technology.

    Hu, Ning; Fang, Jiaru; Zou, Ling; Wan, Hao; Pan, Yuxiang; Su, Kaiqi; Zhang, Xi; Wang, Ping

    2016-10-01

    Cell-based bioassays were effective method to assess the compound toxicity by cell viability, and the traditional label-based methods missed much information of cell growth due to endpoint detection, while the higher throughputs were demanded to obtain dynamic information. Cell-based biosensor methods can dynamically and continuously monitor with cell viability, however, the dynamic information was often ignored or seldom utilized in the toxin and drug assessment. Here, we reported a high-efficient and high-content cytotoxic recording method via dynamic and continuous cell-based impedance biosensor technology. The dynamic cell viability, inhibition ratio and growth rate were derived from the dynamic response curves from the cell-based impedance biosensor. The results showed that the biosensors has the dose-dependent manners to diarrhetic shellfish toxin, okadiac acid based on the analysis of the dynamic cell viability and cell growth status. Moreover, the throughputs of dynamic cytotoxicity were compared between cell-based biosensor methods and label-based endpoint methods. This cell-based impedance biosensor can provide a flexible, cost and label-efficient platform of cell viability assessment in the shellfish toxin screening fields.

  15. A methodological combined framework for roadmapping biosensor research: a fault tree analysis approach within a strategic technology evaluation frame.

    Siontorou, Christina G; Batzias, Fragiskos A

    2014-03-01

    Biosensor technology began in the 1960s to revolutionize instrumentation and measurement. Despite the glucose sensor market success that revolutionized medical diagnostics, and artificial pancreas promise currently the approval stage, the industry is reluctant to capitalize on other relevant university-produced knowledge and innovation. On the other hand, the scientific literature is extensive and persisting, while the number of university-hosted biosensor groups is growing. Considering the limited marketability of biosensors compared to the available research output, the biosensor field has been used by the present authors as a suitable paradigm for developing a methodological combined framework for "roadmapping" university research output in this discipline. This framework adopts the basic principles of the Analytic Hierarchy Process (AHP), replacing the lower level of technology alternatives with internal barriers (drawbacks, limitations, disadvantages), modeled through fault tree analysis (FTA) relying on fuzzy reasoning to count for uncertainty. The proposed methodology is validated retrospectively using ion selective field effect transistor (ISFET) - based biosensors as a case example, and then implemented prospectively membrane biosensors, putting an emphasis on the manufacturability issues. The analysis performed the trajectory of membrane platforms differently than the available market roadmaps that, considering the vast industrial experience in tailoring and handling crystallic forms, suggest the technology path of biomimetic and synthetic materials. The results presented herein indicate that future trajectories lie along with nanotechnology, and especially nanofabrication and nano-bioinformatics, and focused, more on the science-path, that is, on controlling the natural process of self-assembly and the thermodynamics of bioelement-lipid interaction. This retained the nature-derived sensitivity of the biosensor platform, pointing out the differences

  16. Recent advancement in biosensors technology for animal and livestock health management.

    Neethirajan, Suresh; Tuteja, Satish K; Huang, Sheng-Tung; Kelton, David

    2017-12-15

    The term biosensors encompasses devices that have the potential to quantify physiological, immunological and behavioural responses of livestock and multiple animal species. Novel biosensing methodologies offer highly specialised monitoring devices for the specific measurement of individual and multiple parameters covering an animal's physiology as well as monitoring of an animal's environment. These devices are not only highly specific and sensitive for the parameters being analysed, but they are also reliable and easy to use, and can accelerate the monitoring process. Novel biosensors in livestock management provide significant benefits and applications in disease detection and isolation, health monitoring and detection of reproductive cycles, as well as monitoring physiological wellbeing of the animal via analysis of the animal's environment. With the development of integrated systems and the Internet of Things, the continuously monitoring devices are expected to become affordable. The data generated from integrated livestock monitoring is anticipated to assist farmers and the agricultural industry to improve animal productivity in the future. The data is expected to reduce the impact of the livestock industry on the environment, while at the same time driving the new wave towards the improvements of viable farming techniques. This review focusses on the emerging technological advancements in monitoring of livestock health for detailed, precise information on productivity, as well as physiology and well-being. Biosensors will contribute to the 4th revolution in agriculture by incorporating innovative technologies into cost-effective diagnostic methods that can mitigate the potentially catastrophic effects of infectious outbreaks in farmed animals. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Biosensors of bacterial cells.

    Burlage, Robert S; Tillmann, Joshua

    2017-07-01

    Biosensors are devices which utilize both an electrical component (transducer) and a biological component to study an environment. They are typically used to examine biological structures, organisms and processes. The field of biosensors has now become so large and varied that the technology can often seem impenetrable. Yet the principles which underlie the technology are uncomplicated, even if the details of the mechanisms are elusive. In this review we confine our analysis to relatively current advancements in biosensors for the detection of whole bacterial cells. This includes biosensors which rely on an added labeled component and biosensors which do not have a labeled component and instead detect the binding event or bound structure on the transducer. Methods to concentrate the bacteria prior to biosensor analysis are also described. The variety of biosensor types and their actual and potential uses are described. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications

    Luka, George; Ahmadi, Ali; Najjaran, Homayoun; Alocilja, Evangelyn; DeRosa, Maria; Wolthers, Kirsten; Malki, Ahmed; Aziz, Hassan; Althani, Asmaa; Hoorfar, Mina

    2015-01-01

    A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter), increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims at representing advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture. PMID:26633409

  19. Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications

    George Luka

    2015-12-01

    Full Text Available A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter, increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims at representing advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture.

  20. Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time

    Dan Kho

    2015-04-01

    Full Text Available The xCELLigence technology is a real-time cellular biosensor, which measures the net adhesion of cells to high-density gold electrode arrays printed on custom-designed E-plates. The strength of cellular adhesion is influenced by a myriad of factors that include cell type, cell viability, growth, migration, spreading and proliferation. We therefore hypothesised that xCELLigence biosensor technology would provide a valuable platform for the measurement of drug responses in a multitude of different experimental, clinical or pharmacological contexts. In this manuscript, we demonstrate how xCELLigence technology has been invaluable in the identification of (1 not only if cells respond to a particular drug, but (2 the window of drug responsiveness. The latter aspect is often left to educated guess work in classical end-point assays, whereas biosensor technology reveals the temporal profile of the response in real time, which enables both acute responses and longer term responses to be profiled within the same assay. In our experience, the xCELLigence biosensor technology is suitable for highly targeted drug assessment and also low to medium throughput drug screening, which produces high content temporal data in real time.

  1. Biosensor technology for the detection of illegal drugs II: antibody development and detection techniques

    Hilpert, Reinhold; Bauer, Christian; Binder, Florian; Grol, Michael; Hallermayer, Klaus; Josel, Hans-Peter; Klein, Christian; Maier, Josef; Makower, Alexander; Oberpriller, Helmut; Ritter, Josef

    1994-10-01

    In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase and detection by immunological means. This publication covers the development of specific antibodies and various detection procedures. Antibodies with a high affinity for cocaine have been developed with the aid of specially synthesized immunogens. A competitive detection procedure with biosensors based on optical grating couplers and applying particulate labels has been established, showing a lower detection limit of 10-10 mol/l for cocaine. Additionally, a combination of a displacement-immunoreactor and an enzymatically amplified electrode was investigated, which at present still suffers from insufficient sensitivity of the immunoreactor. An alternative, fleece-matrix based test procedure, where enrichment and detection steps are integrated in a single unit, is promising in terms of simplicity and sensitivity. A simple swab-test for the detection of cocaine at surfaces has been developed, which has a lower detection limit of about 10 ng and which can be performed within one minute.

  2. Biosensor technology for the detection of illegal drugs I: objectives, preparatory work, and drug enrichment

    Hilpert, Reinhold; Binder, Florian; Grol, Michael; Hallermayer, Klaus; Josel, Hans-Peter; Klein, Christian; Maier, Josef; Oberpriller, Helmut; Ritter, Josef; Scheller, Frieder W.

    1994-10-01

    In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase and detection by immunological means. This publication covers the description of our objectives, preparatory work and results concerning enrichment of drugs from the gas phase. Vapor pressures of cocaine and cannabinoids have been determined. A test gas generator has been constructed which allows for reproducible preparation of cocaine concentrations between 2 ng/l and 2 pg/l. Coupling of a thermodesorption unit with GC/MS has been established for reference analysis. As another analytical tool, an ELISA with a lower detection limit of about 0,5 pg cocaine/assay has been developed. Applying fleece-type adsorbers, enrichment factors for cocaine in the range of 105 have been realized. No significant interference was found with potentially disturbing substances.

  3. Biosentinel: Improving Desiccation Tolerance of Yeast Biosensors for Deep-Space Missions

    Dalal, Sawan; Santa Maria, Sergio R.; Liddell, Lauren; Bhattacharya, Sharmila

    2017-01-01

    BioSentinel is one of 13 secondary payloads to be deployed on Exploration Mission 1 (EM-1) in 2019. We will use the budding yeast Saccharomyces cerevisiae as a biosensor to determine how deep-space radiation affects living organisms and to potentially quantify radiation levels through radiation damage analysis. Radiation can damage DNA through double strand breaks (DSBs), which can normally be repaired by homologous recombination. Two yeast strains will be air-dried and stored in microfluidic cards within the payload: a wild-type control strain and a radiation sensitive rad51 mutant that is deficient in DSB repairs. Throughout the mission, the microfluidic cards will be rehydrated with growth medium and an indicator dye. Growth rates of each strain will be measured through LED detection of the reduction of the indicator dye, which correlates with DNA repair and the amount of radiation damage accumulated. Results from BioSentinel will be compared to analog experiments on the ISS and on Earth. It is well known that desiccation can damage yeast cells and decrease viability over time. We performed a screen for desiccation-tolerant rad51 strains. We selected 20 re-isolates of rad51 and ran a weekly screen for desiccation-tolerant mutants for five weeks. Our data shows that viability decreases over time, confirming previous research findings. Isolates L2, L5 and L14 indicate desiccation tolerance and are candidates for whole-genome sequencing. More time is needed to determine whether a specific strain is truly desiccation tolerant. Furthermore, we conducted an intracellular trehalose assay to test how intracellular trehalose concentrations affect or protect the mutant strains against desiccation stress. S. cerevisiae cell and reagent concentrations from a previously established intracellular trehalose protocol did not yield significant absorbance measurements, so we tested varying cell and reagent concentrations and determined proper concentrations for successful

  4. Optical Computers and Space Technology

    Abdeldayem, Hossin A.; Frazier, Donald O.; Penn, Benjamin; Paley, Mark S.; Witherow, William K.; Banks, Curtis; Hicks, Rosilen; Shields, Angela

    1995-01-01

    The rapidly increasing demand for greater speed and efficiency on the information superhighway requires significant improvements over conventional electronic logic circuits. Optical interconnections and optical integrated circuits are strong candidates to provide the way out of the extreme limitations imposed on the growth of speed and complexity of nowadays computations by the conventional electronic logic circuits. The new optical technology has increased the demand for high quality optical materials. NASA's recent involvement in processing optical materials in space has demonstrated that a new and unique class of high quality optical materials are processible in a microgravity environment. Microgravity processing can induce improved orders in these materials and could have a significant impact on the development of optical computers. We will discuss NASA's role in processing these materials and report on some of the associated nonlinear optical properties which are quite useful for optical computers technology.

  5. Space power subsystem automation technology

    Graves, J. R. (Compiler)

    1982-01-01

    The technology issues involved in power subsystem automation and the reasonable objectives to be sought in such a program were discussed. The complexities, uncertainties, and alternatives of power subsystem automation, along with the advantages from both an economic and a technological perspective were considered. Whereas most spacecraft power subsystems now use certain automated functions, the idea of complete autonomy for long periods of time is almost inconceivable. Thus, it seems prudent that the technology program for power subsystem automation be based upon a growth scenario which should provide a structured framework of deliberate steps to enable the evolution of space power subsystems from the current practice of limited autonomy to a greater use of automation with each step being justified on a cost/benefit basis. Each accomplishment should move toward the objectives of decreased requirement for ground control, increased system reliability through onboard management, and ultimately lower energy cost through longer life systems that require fewer resources to operate and maintain. This approach seems well-suited to the evolution of more sophisticated algorithms and eventually perhaps even the use of some sort of artificial intelligence. Multi-hundred kilowatt systems of the future will probably require an advanced level of autonomy if they are to be affordable and manageable.

  6. Synthetic Receptor-Based Biosensor for Safety and Security Applications, Phase I

    National Aeronautics and Space Administration — This project will develop a sensitive and specific biosensor worthy of field deployment for autonomous operations. The underlying technology will enable in situ...

  7. Biosensors for Cell Analysis.

    Zhou, Qing; Son, Kyungjin; Liu, Ying; Revzin, Alexander

    2015-01-01

    Biosensors first appeared several decades ago to address the need for monitoring physiological parameters such as oxygen or glucose in biological fluids such as blood. More recently, a new wave of biosensors has emerged in order to provide more nuanced and granular information about the composition and function of living cells. Such biosensors exist at the confluence of technology and medicine and often strive to connect cell phenotype or function to physiological or pathophysiological processes. Our review aims to describe some of the key technological aspects of biosensors being developed for cell analysis. The technological aspects covered in our review include biorecognition elements used for biosensor construction, methods for integrating cells with biosensors, approaches to single-cell analysis, and the use of nanostructured biosensors for cell analysis. Our hope is that the spectrum of possibilities for cell analysis described in this review may pique the interest of biomedical scientists and engineers and may spur new collaborations in the area of using biosensors for cell analysis.

  8. Commercialisation of CMOS Integrated Circuit Technology in Multi-Electrode Arrays for Neuroscience and Cell-Based Biosensors

    Chris R. Bowen

    2011-05-01

    Full Text Available The adaptation of standard integrated circuit (IC technology as a transducer in cell-based biosensors in drug discovery pharmacology, neural interface systems and electrophysiology requires electrodes that are electrochemically stable, biocompatible and affordable. Unfortunately, the ubiquitous Complementary Metal Oxide Semiconductor (CMOS IC technology does not meet the first of these requirements. For devices intended only for research, modification of CMOS by post-processing using cleanroom facilities has been achieved. However, to enable adoption of CMOS as a basis for commercial biosensors, the economies of scale of CMOS fabrication must be maintained by using only low-cost post-processing techniques. This review highlights the methodologies employed in cell-based biosensor design where CMOS-based integrated circuits (ICs form an integral part of the transducer system. Particular emphasis will be placed on the application of multi-electrode arrays for in vitro neuroscience applications. Identifying suitable IC packaging methods presents further significant challenges when considering specific applications. The various challenges and difficulties are reviewed and some potential solutions are presented.

  9. Space Transportation Technology Workshop: Propulsion Research and Technology

    2000-01-01

    This viewgraph presentation gives an overview of the Space Transportation Technology Workshop topics, including Propulsion Research and Technology (PR&T) project level organization, FY 2001 - 2006 project roadmap, points of contact, foundation technologies, auxiliary propulsion technology, PR&T Low Cost Turbo Rocket, and PR&T advanced reusable technologies RBCC test bed.

  10. In-Space Propulsion (346620) Technology Project

    National Aeronautics and Space Administration — Technologies include, but are not limited to, electric and advanced chemical propulsion, propellantless propulsion such as aerocapture and solar sails, sample return...

  11. Surface stress-based biosensors.

    Sang, Shengbo; Zhao, Yuan; Zhang, Wendong; Li, Pengwei; Hu, Jie; Li, Gang

    2014-01-15

    Surface stress-based biosensors, as one kind of label-free biosensors, have attracted lots of attention in the process of information gathering and measurement for the biological, chemical and medical application with the development of technology and society. This kind of biosensors offers many advantages such as short response time (less than milliseconds) and a typical sensitivity at nanogram, picoliter, femtojoule and attomolar level. Furthermore, it simplifies sample preparation and testing procedures. In this work, progress made towards the use of surface stress-based biosensors for achieving better performance is critically reviewed, including our recent achievement, the optimally circular membrane-based biosensors and biosensor array. The further scientific and technological challenges in this field are also summarized. Critical remark and future steps towards the ultimate surface stress-based biosensors are addressed. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Space and Industrial Brine Drying Technologies

    Jones, Harry W.; Wisniewski, Richard S.; Flynn, Michael; Shaw, Hali

    2014-01-01

    This survey describes brine drying technologies that have been developed for use in space and industry. NASA has long considered developing a brine drying system for the International Space Station (ISS). Possible processes include conduction drying in many forms, spray drying, distillation, freezing and freeze drying, membrane filtration, and electrical processes. Commercial processes use similar technologies. Some proposed space systems combine several approaches. The current most promising candidates for use on the ISS use either conduction drying with membrane filtration or spray drying.

  13. The Space House TM : Space Technologies in Architectural Design

    Gampe, F.; Raitt, D.

    2002-01-01

    The word "space" has always been associated with and had a profound impact upon architectural design. Until relatively recently, however, the term has been used in a different sense to that understood by the aerospace community - for them, space was less abstract, more concrete and used in the context of space flight and space exploration, rather than, say, an empty area or space requiring to be filled by furniture. However, the two senses of the word space have now converged to some extent. Interior designers and architects have been involved in designing the interior of Skylab, the structure of the International Space Station, and futuristic space hotels. Today, architects are designing, and builders are building, houses, offices and other structures which incorporate a plethora of new technologies, materials and production processes in an effort not only to introduce innovative and adventurous ideas but also in an attempt to address environmental and social issues. Foremost among these new technologies and materials being considered today are those that have been developed for and by the space industry. This paper examines some of these space technologies, such as energy efficient solar cells, durable plastics, air and water filtration techniques, which have been adapted to both provide power while reducing energy consumption, conserve resources and so on. Several of these technologies have now been employed by the European Space Agency to develop a Space House TM - the first of its kind, which will be deployed not so much on planets like Mars, but rather here on Earth. The Space House TM, which exhibits many innovative features such as high strength light-weight carbon composites, active noise-damped, (glass and plastic) windows, low-cost solar arrays and latent heat storage, air and water purification systems will be described.

  14. Biosensors and environmental health

    Preedy, Victor R; Patel, Vinood B

    2012-01-01

    ..., bacterial biosensors, antibody-based biosensors, enzymatic, amperometric and electrochemical aspects, quorum sensing, DNA-biosensors, cantilever biosensors, bioluminescence and other methods and applications...

  15. Optical biosensors.

    Damborský, Pavel; Švitel, Juraj; Katrlík, Jaroslav

    2016-06-30

    Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surface-enhanced Raman scattering biosensors. The optical biosensors discussed here allow the sensitive and selective detection of a wide range of analytes including viruses, toxins, drugs, antibodies, tumour biomarkers and tumour cells. © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  16. Space Station technology testbed: 2010 deep space transport

    Holt, Alan C.

    1993-01-01

    A space station in a crew-tended or permanently crewed configuration will provide major R&D opportunities for innovative, technology and materials development and advanced space systems testing. A space station should be designed with the basic infrastructure elements required to grow into a major systems technology testbed. This space-based technology testbed can and should be used to support the development of technologies required to expand our utilization of near-Earth space, the Moon and the Earth-to-Jupiter region of the Solar System. Space station support of advanced technology and materials development will result in new techniques for high priority scientific research and the knowledge and R&D base needed for the development of major, new commercial product thrusts. To illustrate the technology testbed potential of a space station and to point the way to a bold, innovative approach to advanced space systems' development, a hypothetical deep space transport development and test plan is described. Key deep space transport R&D activities are described would lead to the readiness certification of an advanced, reusable interplanetary transport capable of supporting eight crewmembers or more. With the support of a focused and highly motivated, multi-agency ground R&D program, a deep space transport of this type could be assembled and tested by 2010. Key R&D activities on a space station would include: (1) experimental research investigating the microgravity assisted, restructuring of micro-engineered, materials (to develop and verify the in-space and in-situ 'tuning' of materials for use in debris and radiation shielding and other protective systems), (2) exposure of microengineered materials to the space environment for passive and operational performance tests (to develop in-situ maintenance and repair techniques and to support the development, enhancement, and implementation of protective systems, data and bio-processing systems, and virtual reality and

  17. The potential of biosensor technology in clinical monitoring and experimental research

    Leegsma-Vogt, G; Rhemrev-Boom, MM; Tiessen, RG; Venema, K; Korf, J

    2004-01-01

    Glucose or lactate biosensors are very useful for monitoring metabolism. Continuous monitoring of glucose is for example very important in diabetic patients. The measurement of lactate, a marker for oxygen deficiency, is used in the intensive care unit to monitor the patients' condition. In our

  18. Free piston space Stirling technology program

    Dochat, G. R.; Dhar, M.

    1989-01-01

    MTI recently completed an initial technology feasibility program for NASA by designing, fabricating and testing a space power demonstrator engine (SPDE). This program, which confirms the potential of free-piston Stirling engines, provided the major impetus to initiate a free-piston Stirling space engine (SSE) technology program. The accomplishments of the SPDE program are reviewed, and an overview of the SSE technology program and technical status to date is provided. It is shown that progress in both programs continues to justify its potential for either nuclear or solar space power missions.

  19. Space Photovoltaic Research and Technology 1995

    Landis, Geoffrey (Compiler)

    1995-01-01

    The Fourteenth Space Photovoltaic Research and Technology conference was held at the NASA Lewis Research Center from October 24-26, 1995. The abstracts presented in this volume report substantial progress in a variety of areas in space photovoltaics. Technical and review papers were presented in many areas, including high efficiency GaAs and InP solar cells, GaAs/Ge cells as commercial items, high efficiency multiple bandgap cells, solar cell and array technology, heteroepitaxial cells, thermophotovoltaic energy conversion, and space radiation effects. Space flight data on a variety of cells were also presented.

  20. Space transportation propulsion USSR launcher technology, 1990

    1991-01-01

    Space transportation propulsion U.S.S.R. launcher technology is discussed. The following subject areas are covered: Energia background (launch vehicle summary, Soviet launcher family) and Energia propulsion characteristics (booster propulsion, core propulsion, and growth capability).

  1. A commercial space technology testbed on ISS

    Boyle, David R.

    2000-01-01

    There is a significant and growing commercial market for new, more capable communications and remote sensing satellites. Competition in this market strongly motivates satellite manufacturers and spacecraft component developers to test and demonstrate new space hardware in a realistic environment. External attach points on the International Space Station allow it to function uniquely as a space technology testbed to satisfy this market need. However, space industry officials have identified three critical barriers to their commercial use of the ISS: unpredictable access, cost risk, and schedule uncertainty. Appropriate NASA policy initiatives and business/technical assistance for industry from the Commercial Space Center for Engineering can overcome these barriers. .

  2. Live from Space Station Learning Technologies Project

    2001-01-01

    This is the Final Report for the Live From Space Station (LFSS) project under the Learning Technologies Project FY 2001 of the MSFC Education Programs Department. AZ Technology, Inc. (AZTek) has developed and implemented science education software tools to support tasks under the LTP program. Initial audience consisted of 26 TreK in the Classroom schools and thousands of museum visitors to the International Space Station: The Earth Tour exhibit sponsored by Discovery Place museum.

  3. New NASA Technologies for Space Exploration

    Calle, Carlos I.

    2015-01-01

    NASA is developing new technologies to enable planetary exploration. NASA's Space Launch System is an advance vehicle for exploration beyond LEO. Robotic explorers like the Mars Science Laboratory are exploring Mars, making discoveries that will make possible the future human exploration of the planet. In this presentation, we report on technologies being developed at NASA KSC for planetary exploration.

  4. Connecting Learning Spaces Using Mobile Technology

    Chen, Wenli; Seow, Peter; So, Hyo-Jeong; Toh, Yancy; Looi, Chee-Kit

    2010-01-01

    The use of mobile technology can help extend children's learning spaces and enrich the learning experiences in their everyday lives where they move from one context to another, switching locations, social groups, technologies, and topics. When students have ubiquitous access to mobile devices with full connectivity, the in-situ use of the mobile…

  5. Integration of Biosensors and Drug Delivery Technologies for Early Detection and Chronic Management of Illness

    Viness Pillay

    2013-06-01

    Full Text Available Recent advances in biosensor design and sensing efficacy need to be amalgamated with research in responsive drug delivery systems for building superior health or illness regimes and ensuring good patient compliance. A variety of illnesses require continuous monitoring in order to have efficient illness intervention. Physicochemical changes in the body can signify the occurrence of an illness before it manifests. Even with the usage of sensors that allow diagnosis and prognosis of the illness, medical intervention still has its downfalls. Late detection of illness can reduce the efficacy of therapeutics. Furthermore, the conventional modes of treatment can cause side-effects such as tissue damage (chemotherapy and rhabdomyolysis and induce other forms of illness (hepatotoxicity. The use of drug delivery systems enables the lowering of side-effects with subsequent improvement in patient compliance. Chronic illnesses require continuous monitoring and medical intervention for efficient treatment to be achieved. Therefore, designing a responsive system that will reciprocate to the physicochemical changes may offer superior therapeutic activity. In this respect, integration of biosensors and drug delivery is a proficient approach and requires designing an implantable system that has a closed loop system. This offers regulation of the changes by means of releasing a therapeutic agent whenever illness biomarkers prevail. Proper selection of biomarkers is vital as this is key for diagnosis and a stimulation factor for responsive drug delivery. By detecting an illness before it manifests by means of biomarkers levels, therapeutic dosing would relate to the severity of such changes. In this review various biosensors and drug delivery systems are discussed in order to assess the challenges and future perspectives of integrating biosensors and drug delivery systems for detection and management of chronic illness.

  6. Application of advanced technology to space automation

    Schappell, R. T.; Polhemus, J. T.; Lowrie, J. W.; Hughes, C. A.; Stephens, J. R.; Chang, C. Y.

    1979-01-01

    Automated operations in space provide the key to optimized mission design and data acquisition at minimum cost for the future. The results of this study strongly accentuate this statement and should provide further incentive for immediate development of specific automtion technology as defined herein. Essential automation technology requirements were identified for future programs. The study was undertaken to address the future role of automation in the space program, the potential benefits to be derived, and the technology efforts that should be directed toward obtaining these benefits.

  7. Strategic Technologies for Deep Space Transport

    Litchford, Ronald J.

    2016-01-01

    Deep space transportation capability for science and exploration is fundamentally limited by available propulsion technologies. Traditional chemical systems are performance plateaued and require enormous Initial Mass in Low Earth Orbit (IMLEO) whereas solar electric propulsion systems are power limited and unable to execute rapid transits. Nuclear based propulsion and alternative energetic methods, on the other hand, represent potential avenues, perhaps the only viable avenues, to high specific power space transport evincing reduced trip time, reduced IMLEO, and expanded deep space reach. Here, key deep space transport mission capability objectives are reviewed in relation to STMD technology portfolio needs, and the advanced propulsion technology solution landscape is examined including open questions, technical challenges, and developmental prospects. Options for potential future investment across the full compliment of STMD programs are presented based on an informed awareness of complimentary activities in industry, academia, OGAs, and NASA mission directorates.

  8. Marshall Space Flight Center Technology Investments Overview

    Tinker, Mike

    2014-01-01

    NASA is moving forward with prioritized technology investments that will support NASA's exploration and science missions, while benefiting other Government agencies and the U.S. aerospace enterprise. center dotThe plan provides the guidance for NASA's space technology investments during the next four years, within the context of a 20-year horizon center dotThis plan will help ensure that NASA develops technologies that enable its 4 goals to: 1.Sustain and extend human activities in space, 2.Explore the structure, origin, and evolution of the solar system, and search for life past and present, 3.Expand our understanding of the Earth and the universe and have a direct and measurable impact on how we work and live, and 4.Energize domestic space enterprise and extend benefits of space for the Nation.

  9. Space Technology for Medical Aids

    1982-01-01

    Under one of the earliest contracts awarded in the Apollo lunar landing program, Parker Hannifin Corporation developed and produced equipment for controlling the flow of propellants into the mammoth engines of the Saturn moonbooster. Today, Parker is supplying the huge valves that control propellant flow from the Space Shuttle's external fuel tank to the engines of the Shuttle Orbiter as well as the "peanut valve," named for its small size. In 1977, NASA, recognizing the company's special expertise in miniature systems, asked Parker to participate in the development of an implantable artificial sphincter for control of urinary incontinence. The company's peanut valve experience provided an ideal base for a new biomedical project, the Programmable Implantable Medication System (PIMS) for continuous, computer-directed delivery of precisely metered medication -- insulin, for example -- within a patient's body. The work on PIMS also inspired development of Micromed, a related programmable medication device for external, rather than implantable use. The Biomedical Products Division has also applied its fluid handling expertise to a drugless therapy system called Cryomax for the treatment of such disorders as rheumatoid arthritis and lupus.

  10. National Aeronautics and Space Administration plans for space communication technology

    Alexovich, R. E.

    1979-01-01

    A program plan is presented for a space communications application utilizing the 30/20 GHz frequency bands (30 GHz uplink and 20 GHz downlink). Results of market demand studies and spacecraft systems studies which significantly affect the supporting research and technology program are also presented, along with the scheduled activities of the program plan.

  11. Technology transfer trends in Indian space programme

    Sridhara Murthi, K. R.; Shoba, T. S.

    2010-10-01

    Indian space programme, whose objectives involve acceleration of economic and social development through applications of space technology, has been engaged in the development of state-of-the-art satellite systems, launch vehicles and equipment necessary for applications. Even during the early phase of evolution of this Programme, deliberate policies have been adopted by the national space agency, namely, Indian Space Research Organisation (ISRO), to promote spin-off benefit from the technologies developed for the use of space projects. Consistently adhering to this policy, ISRO has transferred over 280 technologies till date, spanning a wide spectrum of disciplines. This has resulted in a fruitful two-way cooperation between a number of SMEs and the ISRO. In order to make the technology transfer process effective, ISRO has adopted a variety of functional and organizational policies that included awareness building measures, licensee selection methods, innovative contract systems, diverse transfer processes, post licencing services and feedback mechanisms. Besides analyzing these policies and their evolution, the paper discusses various models adopted for technology transfer and their impact on assessment. It also touches upon relevant issues relating to creating interface between public funded R&D and the private commercial enterprises. It suggests few models in which international cooperation could be pursued in this field.

  12. Technology Applications that Support Space Exploration

    Henderson, Edward M.; Holderman, Mark L.

    2011-01-01

    Several enabling technologies have been identified that would provide significant benefits for future space exploration. In-Space demonstrations should be chosen so that these technologies will have a timely opportunity to improve efficiencies and reduce risks for future spaceflight. An early window exists to conduct ground and flight demonstrations that make use of existing assets that were developed for the Space Shuttle and the Constellation programs. The work could be mostly performed using residual program civil servants, existing facilities and current commercial launch capabilities. Partnering these abilities with the emerging commercial sector, along with other government agencies, academia and with international partners would provide an affordable and timely approach to get the launch costs down for these payloads, while increasing the derived benefits to a larger community. There is a wide scope of varied technologies that are being considered to help future space exploration. However, the cost and schedule would be prohibitive to demonstrate all these in the near term. Determining which technologies would yield the best return in meeting our future space needs is critical to building an achievable Space Architecture that allows exploration beyond Low Earth Orbit. The best mix of technologies is clearly to be based on our future needs, but also must take into account the availability of existing assets and supporting partners. Selecting those technologies that have complimentary applications will provide the most knowledge, with reasonable cost, for future use The plan is to develop those applications that not only mature the technology but actually perform a useful task or mission. These might include such functions as satellite servicing, a propulsion stage, processing lunar regolith, generating and transmitting solar power, cryogenic fluid transfer and storage and artificial gravity. Applications have been selected for assessment for future

  13. Affinity biosensors: techniques and protocols

    Rogers, Kim R; Mulchandani, Ashok

    1998-01-01

    ..., and government to begin or expand their biosensors research. This volume, Methods in Biotechnology vol. 7: Affinity Biosensors: Techniques and Protocols, describes a variety of classical and emerging transduction technologies that have been interfaced to bioaffinity elements (e.g., antibodies and receptors). Some of the reas...

  14. The space shuttle program technologies and accomplishments

    Sivolella, Davide

    2017-01-01

    This book tells the story of the Space Shuttle in its many different roles as orbital launch platform, orbital workshop, and science and technology laboratory. It focuses on the technology designed and developed to support the missions of the Space Shuttle program. Each mission is examined, from both the technical and managerial viewpoints. Although outwardly identical, the capabilities of the orbiters in the late years of the program were quite different from those in 1981. Sivolella traces the various improvements and modifications made to the shuttle over the years as part of each mission story. Technically accurate but with a pleasing narrative style and simple explanations of complex engineering concepts, the book provides details of many lesser known concepts, some developed but never flown, and commemorates the ingenuity of NASA and its partners in making each Space Shuttle mission push the boundaries of what we can accomplish in space. Using press kits, original papers, newspaper and magazine articles...

  15. Technology transfer from the space exploration initiative

    Buden, D.

    1991-01-01

    Space exploration has demonstrated that it stimulates the national economy by creating new and improved products, increased employment, and provides a stimulus to education. The exploration of the Moon and Mars under the Space Exploration Initiative has the potential of accelerating this stimulates to the economy. It is difficult to identify all of the concrete ways this will be accomplished. However, many areas can be identified. The space exploration building blocks of power, propulsion, spacecraft, robotics, rovers, mining and manufacturing, communications, navigation, habitats, life support and infrastructures are reviewed to identify possible technology areas. For example, better means for working in hazardous areas and handling hazardous waste are potential outcomes of this initiative. Methods to produce higher quality goods and improve America's competitiveness in manufacturing will undoubtedly evolve from the need to produce products that must last many years in the harsh environments of space and planetary surfaces. Some ideas for technology transfer are covered in this paper

  16. Medical technology advances from space research

    Pool, S. L.

    1972-01-01

    Details of medical research and development programs, particularly an integrated medical laboratory, as derived from space technology are given. The program covers digital biotelemetry systems, automatic visual field mapping equipment, sponge electrode caps for clinical electroencephalograms, and advanced respiratory analysis equipment. The possibility of using the medical laboratory in ground based remote areas and regional health care facilities, as well as long duration space missions is discussed.

  17. Technology evaluation for space station atmospheric leakage

    Lemon, D.K.; Friesel, M.A.; Griffin, J.W.; Skorpik, J.R.; Shepard, C.L.; Antoniak, Z.I.; Kurtz, R.J.

    1990-02-01

    A concern in operation of a space station is leakage of atmosphere through seal points and through the walls as a result of damage from particle (space debris and micrometeoroid) impacts. This report describes a concept for a monitoring system to detect atmosphere leakage and locate the leak point. The concept is based on analysis and testing of two basic methods selected from an initial technology survey of potential approaches. 18 refs., 58 figs., 5 tabs.

  18. Space weather effects on ground based technology

    Clark, T.

    Space weather can affect a variety of forms of ground-based technology, usually as a result of either the direct effects of the varying geomagnetic field, or as a result of the induced electric field that accompanies such variations. Technologies affected directly by geomagnetic variations include magnetic measurements made d ringu geophysical surveys, and navigation relying on the geomagnetic field as a direction reference, a method that is particularly common in the surveying of well-bores in the oil industry. The most obvious technology affected by induced electric fields during magnetic storms is electric power transmission, where the example of the blackout in Quebec during the March 1989 magnetic storm is widely known. Additionally, space weather effects must be taken into account in the design of active cathodic protection systems on pipelines to protect them against corrosion. Long-distance telecommunication cables may also have to be designed to cope with space weather related effects. This paper reviews the effects of space weather in these different areas of ground-based technology, and provides examples of how mitigation against hazards may be achieved. (The paper does not include the effects of space weather on radio communication or satellite navigation systems).

  19. The Personal Health Technology Design Space

    Bardram, Jakob Eyvind; Frost, Mads

    2016-01-01

    . To enable designers to make informed and well-articulated design decision, the authors propose a design space for personal health technologies. This space consists of 10 dimensions related to the design of data sampling strategies, visualization and feedback approaches, treatment models, and regulatory......Interest is increasing in personal health technologies that utilize mobile platforms for improved health and well-being. However, although a wide variety of these systems exist, each is designed quite differently and materializes many different and more or less explicit design assumptions...

  20. UWB Technology and Applications on Space Exploration

    Ngo, Phong; Phan, Chau; Gross, Julia; Dusl, John; Ni, Jianjun; Rafford, Melinda

    2006-01-01

    Ultra-wideband (UWB), also known as impulse or carrier-free radio technology, is one promising new technology. In February 2002, the Federal Communications Commission (FCC) approved the deployment of this technology. It is increasingly recognized that UWB technology holds great potential to provide significant benefits in many terrestrial and space applications such as precise positioning/tracking and high data rate mobile wireless communications. This talk presents an introduction to UWB technology and some applications on space exploration. UWB is characterized by several uniquely attractive features, such as low impact on other RF systems due to its extremely low power spectral densities, immunity to interference from narrow band RF systems due to its ultra-wide bandwidth, multipath immunity to fading due to ample multipath diversity, capable of precise positioning due to fine time resolution, capable of high data rate multi-channel performance. The related FCC regulations, IEEE standardization efforts and industry activities also will be addressed in this talk. For space applications, some projects currently under development at NASA Johnson Space Center will be introduced. These include the UWB integrated communication and tracking system for Lunar/Mars rover and astronauts, UWB-RFID ISS inventory tracking, and UWB-TDOA close-in high resolution tracking for potential applications on robonaut.

  1. In-Space Inspection Technologies Vision

    Studor, George

    2012-01-01

    Purpose: Assess In-Space NDE technologies and needs - current & future spacecraft. Discover & build on needs, R&D & NDE products in other industries and agencies. Stimulate partnerships in & outside NASA to move technologies forward cooperatively. Facilitate group discussion on challenges and opportunities of mutual benefit. Focus Areas: Miniaturized 3D Penetrating Imagers Controllable Snake-arm Inspection systems Miniature Free-flying Micro-satellite Inspectors

  2. Recent trends in space mapping technology

    Bandler, John W.; Cheng, Qingsha S.; Hailu, Daniel

    2004-01-01

    We review recent trends in the art of Space Mapping (SM) technology for modeling and design of engineering devices and systems. The SM approach aims at achieving a satisfactory solution with a handful of computationally expensive so-called "fine" model evaluations. SM procedures iteratively update...

  3. CSIR eNews: Space technology

    CSIR

    2008-03-01

    Full Text Available The CSIR Satellite Applications Centre is a key component of the CSIR's efforts to maximise the benefit of information, communications and space technology for industry and society. The centre at Hartebeesthoek is located some 70 km west of Pretoria...

  4. CSIR eNews: Space technology

    CSIR

    2009-09-01

    Full Text Available The CSIR Satellite Applications Centre is a key component of the CSIR's efforts to maximise the benefit of information, communications and space technology for industry and society. The centre at Hartebeesthoek is located some 70 km west of Pretoria...

  5. CSIR eNews: Space technology

    CSIR

    2007-12-01

    Full Text Available The CSIR Satellite Applications Centre is a key component of the CSIR's efforts to maximise the benefit of information, communications and space technology for industry and society. The centre at Hartebeesthoek is located some 70 km west of Pretoria...

  6. CSIR eNews: Space technology

    CSIR

    2008-12-01

    Full Text Available The CSIR Satellite Applications Centre is a key component of the CSIR's efforts to maximise the benefit of information, communications and space technology for industry and society. The centre at Hartebeesthoek is located some 70 km west of Pretoria...

  7. Technology transfer of military space microprocessor developments

    Gorden, C.; King, D.; Byington, L.; Lanza, D.

    1999-01-01

    Over the past 13 years the Air Force Research Laboratory (AFRL) has led the development of microprocessors and computers for USAF space and strategic missile applications. As a result of these Air Force development programs, advanced computer technology is available for use by civil and commercial space customers as well. The Generic VHSIC Spaceborne Computer (GVSC) program began in 1985 at AFRL to fulfill a deficiency in the availability of space-qualified data and control processors. GVSC developed a radiation hardened multi-chip version of the 16-bit, Mil-Std 1750A microprocessor. The follow-on to GVSC, the Advanced Spaceborne Computer Module (ASCM) program, was initiated by AFRL to establish two industrial sources for complete, radiation-hardened 16-bit and 32-bit computers and microelectronic components. Development of the Control Processor Module (CPM), the first of two ASCM contract phases, concluded in 1994 with the availability of two sources for space-qualified, 16-bit Mil-Std-1750A computers, cards, multi-chip modules, and integrated circuits. The second phase of the program, the Advanced Technology Insertion Module (ATIM), was completed in December 1997. ATIM developed two single board computers based on 32-bit reduced instruction set computer (RISC) processors. GVSC, CPM, and ATIM technologies are flying or baselined into the majority of today's DoD, NASA, and commercial satellite systems.

  8. Terahertz antenna technology for space applications

    Choudhury, Balamati; Jha, Rakesh Mohan

    2016-01-01

    This book explores the terahertz antenna technology towards implementation of compact, consistent and cheap terahertz sources, as well as the high sensitivity terahertz detectors. The terahertz EM band provides a transition between the electronic and the photonic regions thus adopting important characteristics from these regimes. These characteristics, along with the progress in semiconductor technology, have enabled researchers to exploit hitherto unexplored domains including satellite communication, bio-medical imaging, and security systems. The advances in new materials and nanostructures such as graphene will be helpful in miniaturization of antenna technology while simultaneously maintaining the desired output levels. Terahertz antenna characterization of bandwidth, impedance, polarization, etc. has not yet been methodically structured and it continues to be a major research challenge. This book addresses these issues besides including the advances of terahertz technology in space applications worldwide,...

  9. Guided-Wave Optical Biosensors

    Passaro, Vittorio M. N.; Dell'Olio, Francesco; Casamassima, Biagio; De Leonardis, Francesco

    2007-01-01

    Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonance, hollow and antiresonant waveguides, and Bragg gratings to realize very sensitive and selective, ultra-compact and fast biosensors is discussed. Finally, CMOS-compatible technologies are proved to be the most attractive for fabrication of guided-wave photonic biosensors.

  10. Technology of hardening fills for mined spaces

    Simek, P.; Holas, M.; Chyla, A.; Pech, P.

    1985-01-01

    The technology is described of hardening fills for mined spaces of uranium deposits in North Bohemian chalk. A special equipment was developed for the controlled preparation of a hardening mixture. The composition of the fill is determined by the strength of the filled rock, expecially by the standard strength, i.e., the minimal strength of the filling under uniaxial pressure. The said parameter determines the consumption of binding materials and thereby the total costs of the filling. A description is presented of the filling technology, including rabbit tube transport of the mixture and quality control. (Pu)

  11. Technology R&D for space commerce

    Sadin, Stanley R.; Christensen, Carissa B.; Steen, Robert G.

    1992-01-01

    The potential effects of reserach conducted by the NASA Office of Aeronautics and Space Technology, OAST, on the aerospace industry are addressed. Program elements aimed at meeting commercial needs and those aimed at meeting NASA needs which have secondary effects benefiting aerospace firms are considered. Particular attention is given to current and future NASA programs for cooperating with industry and the potential effects of OAST research on nonaerospace industries.

  12. Innovative technologies in urban mapping built space and mental space

    Paolini, Paolo; Salerno, Rossella

    2014-01-01

    The book presents a comprehensive vision of the impact of ICT on the contemporary city, heritage, public spaces and meta-cities on both urban and metropolitan scales, not only in producing innovative perspectives but also related to newly discovered scientific methods, which can be used to stimulate the emerging reciprocal relations between cities and information technologies. Using the principles established by multi-disciplinary interventions as examples and then expanding on them, this book demonstrates how by using ICT and new devices, metropolises can be organized for a future that preserves the historic nucleus of the city and the environment while preparing the necessary expansion of transportation, housing and industrial facilities.

  13. Maturing Technologies for Stirling Space Power Generation

    Wilson, Scott D.; Nowlin, Brentley C.; Dobbs, Michael W.; Schmitz, Paul C.; Huth, James

    2016-01-01

    Stirling Radioisotope Power Systems (RPS) are being developed as an option to provide power on future space science missions where robotic spacecraft will orbit, flyby, land or rove. A Stirling Radioisotope Generator (SRG) could offer space missions a more efficient power system that uses one fourth of the nuclear fuel and decreases the thermal footprint of the current state of the art. The RPS Program Office, working in collaboration with the U.S. Department of Energy (DOE), manages projects to develop thermoelectric and dynamic power systems, including Stirling Radioisotope Generators (SRGs). The Stirling Cycle Technology Development (SCTD) Project, located at Glenn Research Center (GRC), is developing Stirling-based subsystems, including convertors and controllers. The SCTD Project also performs research that focuses on a wide variety of objectives, including increasing convertor temperature capability to enable new environments, improving system reliability or fault tolerance, reducing mass or size, and developing advanced concepts that are mission enabling. Research activity includes maturing subsystems, assemblies, and components to prepare them for infusion into future convertor and generator designs. The status of several technology development efforts are described here. As part of the maturation process, technologies are assessed for readiness in higher-level subsystems. To assess the readiness level of the Dual Convertor Controller (DCC), a Technology Readiness Assessment (TRA) was performed and the process and results are shown. Stirling technology research is being performed by the SCTD Project for NASA's RPS Program Office, where tasks focus on maturation of Stirling-based systems and subsystems for future space science missions.

  14. Introduction to biosensors.

    Bhalla, Nikhil; Jolly, Pawan; Formisano, Nello; Estrela, Pedro

    2016-06-30

    Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics and biomedical research. A wide range of techniques can be used for the development of biosensors. Their coupling with high-affinity biomolecules allows the sensitive and selective detection of a range of analytes. We give a general introduction to biosensors and biosensing technologies, including a brief historical overview, introducing key developments in the field and illustrating the breadth of biomolecular sensing strategies and the expansion of nanotechnological approaches that are now available. © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  15. Microbial biosensors

    Le Yu; Chen, Wilfred; Mulchandani, Ashok

    2006-01-01

    A microbial biosensor is an analytical device that couples microorganisms with a transducer to enable rapid, accurate and sensitive detection of target analytes in fields as diverse as medicine, environmental monitoring, defense, food processing and safety. The earlier microbial biosensors used the respiratory and metabolic functions of the microorganisms to detect a substance that is either a substrate or an inhibitor of these processes. Recently, genetically engineered microorganisms based on fusing of the lux, gfp or lacZ gene reporters to an inducible gene promoter have been widely applied to assay toxicity and bioavailability. This paper reviews the recent trends in the development and application of microbial biosensors. Current advances and prospective future direction in developing microbial biosensor have also been discussed

  16. The international handbook of space technology

    Badescu, Viorel

    2014-01-01

    This comprehensive handbook provides an overview of space technology and a holistic understanding of the system-of-systems that is a modern spacecraft. With a foreword by Elon Musk, CEO and CTO of SpaceX, and contributions from globally leading agency experts from NASA, ESA, JAXA, and CNES, as well as European and North American academics and industrialists, this handbook, as well as giving an interdisciplinary overview, offers, through individual self-contained chapters, more detailed understanding of specific fields, ranging through: ·         Launch systems, structures, power, thermal, communications, propulsion, and software, to ·         entry, descent and landing, ground segment, robotics, and data systems, to ·         technology management, legal and regulatory issues, and project management. This handbook is an equally invaluable asset to those on a career path towards the space industry as it is to those already within the industry.

  17. In-Space Propulsion Technology Program Solar Electric Propulsion Technologies

    Dankanich, John W.

    2006-01-01

    NASA's In-space Propulsion (ISP) Technology Project is developing new propulsion technologies that can enable or enhance near and mid-term NASA science missions. The Solar Electric Propulsion (SEP) technology area has been investing in NASA s Evolutionary Xenon Thruster (NEXT), the High Voltage Hall Accelerator (HiVHAC), lightweight reliable feed systems, wear testing, and thruster modeling. These investments are specifically targeted to increase planetary science payload capability, expand the envelope of planetary science destinations, and significantly reduce the travel times, risk, and cost of NASA planetary science missions. Status and expected capabilities of the SEP technologies are reviewed in this presentation. The SEP technology area supports numerous mission studies and architecture analyses to determine which investments will give the greatest benefit to science missions. Both the NEXT and HiVHAC thrusters have modified their nominal throttle tables to better utilize diminished solar array power on outbound missions. A new life extension mechanism has been implemented on HiVHAC to increase the throughput capability on low-power systems to meet the needs of cost-capped missions. Lower complexity, more reliable feed system components common to all electric propulsion (EP) systems are being developed. ISP has also leveraged commercial investments to further validate new ion and hall thruster technologies and to potentially lower EP mission costs.

  18. Optical biosensor technologies for molecular diagnostics at the point-of-care

    Schotter, Joerg; Schrittwieser, Stefan; Muellner, Paul; Melnik, Eva; Hainberger, Rainer; Koppitsch, Guenther; Schrank, Franz; Soulantika, Katerina; Lentijo-Mozo, Sergio; Pelaz, Beatriz; Parak, Wolfgang; Ludwig, Frank; Dieckhoff, Jan

    2015-05-01

    Label-free optical schemes for molecular biosensing hold a strong promise for point-of-care applications in medical research and diagnostics. Apart from diagnostic requirements in terms of sensitivity, specificity, and multiplexing capability, also other aspects such as ease of use and manufacturability have to be considered in order to pave the way to a practical implementation. We present integrated optical waveguide as well as magnetic nanoparticle based molecular biosensor concepts that address these aspects. The integrated optical waveguide devices are based on low-loss photonic wires made of silicon nitride deposited by a CMOS compatible plasma-enhanced chemical vapor deposition (PECVD) process that allows for backend integration of waveguides on optoelectronic CMOS chips. The molecular detection principle relies on evanescent wave sensing in the 0.85 μm wavelength regime by means of Mach-Zehnder interferometers, which enables on-chip integration of silicon photodiodes and, thus, the realization of system-on-chip solutions. Our nanoparticle-based approach is based on optical observation of the dynamic response of functionalized magneticcore/ noble-metal-shell nanorods (`nanoprobes') to an externally applied time-varying magnetic field. As target molecules specifically bind to the surface of the nanoprobes, the observed dynamics of the nanoprobes changes, and the concentration of target molecules in the sample solution can be quantified. This approach is suitable for dynamic real-time measurements and only requires minimal sample preparation, thus presenting a highly promising point-of-care diagnostic system. In this paper, we present a prototype of a diagnostic device suitable for highly automated sample analysis by our nanoparticle-based approach.

  19. The space technology demand on materials and processes

    Dauphin, J.

    1983-01-01

    Space technology requires a rational and accurate policy of materials and processes selection. This paper examines some areas of space technology where materials and process problems have occurred in the past and how they can be solved in the future.

  20. Internet Technology for Future Space Missions

    Hennessy, Joseph F. (Technical Monitor); Rash, James; Casasanta, Ralph; Hogie, Keith

    2002-01-01

    Ongoing work at National Aeronautics and Space Administration Goddard Space Flight Center (NASA/GSFC), seeks to apply standard Internet applications and protocols to meet the technology challenge of future satellite missions. Internet protocols and technologies are under study as a future means to provide seamless dynamic communication among heterogeneous instruments, spacecraft, ground stations, constellations of spacecraft, and science investigators. The primary objective is to design and demonstrate in the laboratory the automated end-to-end transport of files in a simulated dynamic space environment using off-the-shelf, low-cost, commodity-level standard applications and protocols. The demonstrated functions and capabilities will become increasingly significant in the years to come as both earth and space science missions fly more sensors and the present labor-intensive, mission-specific techniques for processing and routing data become prohibitively. This paper describes how an IP-based communication architecture can support all existing operations concepts and how it will enable some new and complex communication and science concepts. The authors identify specific end-to-end data flows from the instruments to the control centers and scientists, and then describe how each data flow can be supported using standard Internet protocols and applications. The scenarios include normal data downlink and command uplink as well as recovery scenarios for both onboard and ground failures. The scenarios are based on an Earth orbiting spacecraft with downlink data rates from 300 Kbps to 4 Mbps. Included examples are based on designs currently being investigated for potential use by the Global Precipitation Measurement (GPM) mission.

  1. Nonvolatile Memory Technology for Space Applications

    Oldham, Timothy R.; Irom, Farokh; Friendlich, Mark; Nguyen, Duc; Kim, Hak; Berg, Melanie; LaBel, Kenneth A.

    2010-01-01

    This slide presentation reviews several forms of nonvolatile memory for use in space applications. The intent is to: (1) Determine inherent radiation tolerance and sensitivities, (2) Identify challenges for future radiation hardening efforts, (3) Investigate new failure modes and effects, and technology modeling programs. Testing includes total dose, single event (proton, laser, heavy ion), and proton damage (where appropriate). Test vehicles are expected to be a variety of non-volatile memory devices as available including Flash (NAND and NOR), Charge Trap, Nanocrystal Flash, Magnetic Memory (MRAM), Phase Change--Chalcogenide, (CRAM), Ferroelectric (FRAM), CNT, and Resistive RAM.

  2. Research & Technology Report Goddard Space Flight Center

    Soffen, Gerald A. (Editor); Truszkowski, Walter (Editor); Ottenstein, Howard (Editor); Frost, Kenneth (Editor); Maran, Stephen (Editor); Walter, Lou (Editor); Brown, Mitch (Editor)

    1995-01-01

    The main theme of this edition of the annual Research and Technology Report is Mission Operations and Data Systems. Shifting from centralized to distributed mission operations, and from human interactive operations to highly automated operations is reported. The following aspects are addressed: Mission planning and operations; TDRSS, Positioning Systems, and orbit determination; hardware and software associated with Ground System and Networks; data processing and analysis; and World Wide Web. Flight projects are described along with the achievements in space sciences and earth sciences. Spacecraft subsystems, cryogenic developments, and new tools and capabilities are also discussed.

  3. Definition of technology development missions for early space stations. Large space structures, phase 2, midterm review

    1984-01-01

    The large space structures technology development missions to be performed on an early manned space station was studied and defined and the resources needed and the design implications to an early space station to carry out these large space structures technology development missions were determined. Emphasis is being placed on more detail in mission designs and space station resource requirements.

  4. Bees as Biosensors: Chemosensory Ability, Honey Bee Monitoring Systems, and Emergent Sensor Technologies Derived from the Pollinator Syndrome

    Bromenshenk, Jerry J.; Henderson, Colin B.; Seccomb, Robert A.; Welch, Phillip M.; Debnam, Scott E.; Firth, David R.

    2015-01-01

    This review focuses on critical milestones in the development path for the use of bees, mainly honey bees and bumble bees, as sentinels and biosensors. These keystone species comprise the most abundant pollinators of agro-ecosystems. Pollinating 70%–80% of flowering terrestrial plants, bees and other insects propel the reproduction and survival of plants and themselves, as well as improve the quantity and quality of seeds, nuts, and fruits that feed birds, wildlife, and us. Flowers provide insects with energy, nutrients, and shelter, while pollinators are essential to global ecosystem productivity and stability. A rich and diverse milieu of chemical signals establishes and maintains this intimate partnership. Observations of bee odor search behavior extend back to Aristotle. In the past two decades great strides have been made in methods and instrumentation for the study and exploitation of bee search behavior and for examining intra-organismal chemical communication signals. In particular, bees can be trained to search for and localize sources for a variety of chemicals, which when coupled with emerging tracking and mapping technologies create novel potential for research, as well as bee and crop management. PMID:26529030

  5. Bees as Biosensors: Chemosensory Ability, Honey Bee Monitoring Systems, and Emergent Sensor Technologies Derived from the Pollinator Syndrome.

    Bromenshenk, Jerry J; Henderson, Colin B; Seccomb, Robert A; Welch, Phillip M; Debnam, Scott E; Firth, David R

    2015-10-30

    This review focuses on critical milestones in the development path for the use of bees, mainly honey bees and bumble bees, as sentinels and biosensors. These keystone species comprise the most abundant pollinators of agro-ecosystems. Pollinating 70%-80% of flowering terrestrial plants, bees and other insects propel the reproduction and survival of plants and themselves, as well as improve the quantity and quality of seeds, nuts, and fruits that feed birds, wildlife, and us. Flowers provide insects with energy, nutrients, and shelter, while pollinators are essential to global ecosystem productivity and stability. A rich and diverse milieu of chemical signals establishes and maintains this intimate partnership. Observations of bee odor search behavior extend back to Aristotle. In the past two decades great strides have been made in methods and instrumentation for the study and exploitation of bee search behavior and for examining intra-organismal chemical communication signals. In particular, bees can be trained to search for and localize sources for a variety of chemicals, which when coupled with emerging tracking and mapping technologies create novel potential for research, as well as bee and crop management.

  6. Bees as Biosensors: Chemosensory Ability, Honey Bee Monitoring Systems, and Emergent Sensor Technologies Derived from the Pollinator Syndrome

    Jerry J. Bromenshenk

    2015-10-01

    Full Text Available This review focuses on critical milestones in the development path for the use of bees, mainly honey bees and bumble bees, as sentinels and biosensors. These keystone species comprise the most abundant pollinators of agro-ecosystems. Pollinating 70%–80% of flowering terrestrial plants, bees and other insects propel the reproduction and survival of plants and themselves, as well as improve the quantity and quality of seeds, nuts, and fruits that feed birds, wildlife, and us. Flowers provide insects with energy, nutrients, and shelter, while pollinators are essential to global ecosystem productivity and stability. A rich and diverse milieu of chemical signals establishes and maintains this intimate partnership. Observations of bee odor search behavior extend back to Aristotle. In the past two decades great strides have been made in methods and instrumentation for the study and exploitation of bee search behavior and for examining intra-organismal chemical communication signals. In particular, bees can be trained to search for and localize sources for a variety of chemicals, which when coupled with emerging tracking and mapping technologies create novel potential for research, as well as bee and crop management.

  7. Space technology and robotics in school projects

    Villias, Georgios

    2016-04-01

    Space-related educational activities is a very inspiring and attractive way to involve students into science courses, present them the variety of STEM careers that they can follow, while giving them at the same time the opportunity to develop various practical and communication skills necessary for their future professional development. As part of a large scale extracurricular course in Space Science, Space Technology and Robotics that has been introduced in our school, our students, divided in smaller groups of 3-4 students in each, try to understand the challenges that current and future space exploration is facing. Following a mixture of an inquiry-based learning methodology and hands-on practical activities related with constructions and experiments, students get a glimpse of the pre-mentioned fields. Our main goal is to gain practical knowledge and inspiration from the exciting field of Space, to attain an adequate level of team spirit and effective cooperation, while developing technical and research data-mining skills. We use the following two approaches: 1. Constructive (Technical) approach Designing and constructing various customized robotic machines, that will simulate the future space exploration vehicles and satellites needed to study the atmosphere, surface and subsurface of planets, moons or other planetary bodies of our solar system that have shown some promising indications for the existence of life, taking seriously into account their special characteristics and known existing conditions (like Mars, Titan, Europa & Enceladus). The STEM tools we use are the following: - LEGO Mindstorms: to construct rovers for surface exploration. - Hydrobots: an MIT's SeaPerch program for the construction of submarine semi-autonomous robots. - CanSats: Arduino-based microsatellites able to receive, record & transmit data. - Space balloons: appropriate for high altitude atmospheric measurements & photography. 2. Scientific approach Conducting interesting physics

  8. Sustainable In-Space Manufacturing through Rapid Prototyping Technology

    National Aeronautics and Space Administration — In space manufacturing is crucial to humanity’s continued exploration and habitation of space. While new spacecraft and propulsion technologies promise higher...

  9. STAIF96: space technology and applications international forum. Proceedings

    El-Genk, M.S.

    1996-01-01

    These proceedings represent papers presented at the Space Technology and Applications International Forum-STAIF. STAIF-96 hosted four technical conferences sharing the common interest in space exploration, technology, and commercialization. Topics discussed include space station, space transportation, materials processing in space, commercial forum, space power, commercial space ports, microelectronics, automation of robotics-space application, remote sensing, small business innovative research and communications. There were 243 papers presented at the forum, and 138 have been abstracted for the Energy Science and Technology database. STAIF-96 was partly sponsored by the U.S. Department of Energy

  10. NASA space station automation: AI-based technology review

    Firschein, O.; Georgeff, M. P.; Park, W.; Neumann, P.; Kautz, W. H.; Levitt, K. N.; Rom, R. J.; Poggio, A. A.

    1985-01-01

    Research and Development projects in automation for the Space Station are discussed. Artificial Intelligence (AI) based automation technologies are planned to enhance crew safety through reduced need for EVA, increase crew productivity through the reduction of routine operations, increase space station autonomy, and augment space station capability through the use of teleoperation and robotics. AI technology will also be developed for the servicing of satellites at the Space Station, system monitoring and diagnosis, space manufacturing, and the assembly of large space structures.

  11. Biosensors based on gold nanostructures

    Vidotti,Marcio; Carvalhal,Rafaela F.; Mendes,Renata K.; Ferreira,Danielle C. M.; Kubota,Lauro T.

    2011-01-01

    The present review discusses the latest advances in biosensor technology achieved by the assembly of biomolecules associated with gold nanoparticles in analytical devices. This review is divided in sections according to the biomolecule employed in the biosensor development: (i) immunocompounds; (ii) DNA/RNA and functional DNA/RNA; and (iii) enzymes and Heme proteins. In order to facilitate the comprehension each section was subdivided according to the transduction mode. Gold nanoparticles bas...

  12. Uptake of Space Technologies - An Educational Programme

    Bacai, Hina; Zolotikova, Svetlana; Young, Mandy; Cowsill, Rhys; Wells, Alan; Monks, Paul; Archibald, Alexandra; Smith, Teresa

    2013-04-01

    Earth Observation data and remote sensing technologies have been maturing into useful tools that can be utilised by local authorities and businesses to aid in activates such as monitoring climate change trends and managing agricultural land and water uses. The European Earth observation programme Copernicus, previously known as GMES (Global Monitoring for Environment and Security), provides the means to collect and process multi-source EO and environmental data that supports policy developments at the European level. At the regional and local level, the Copernicus programme has been initiated through Regional Contact Office (RCO), which provide knowledge, training, and access to expertise both locally and at a European level through the network of RCOs established across Europe in the DORIS_Net (Downstream Observatory organised by Regions active In Space - Network) project (Grant Agreement No. 262789 Coordination and support action (Coordinating) FP7 SPA.2010.1.1-07 "Fostering downstream activities and links with regions"). In the East Midlands UK RCO, educational and training workshops and modules have been organised to highlight the wider range of tools and application available to businesses and local authorities in the region. Engagement with businesses and LRA highlighted the need to have a tiered system of training to build awareness prior to investigating innovative solutions and space technology uses for societal benefits. In this paper we outline education and training programmes which have been developed at G-STEP (GMES - Science and Technology Education Partnership), University of Leicester, UK to open up the Copernicus programme through the Regional Contact Office to downstream users such as local businesses and LRAs. Innovative methods to introduce the operational uses of Space technologies in real cases through e-learning modules and web-based tools will be described and examples of good practice for educational training in these sectors will be

  13. Cognition and learning in space technology

    Kelber Ruhena Abrão

    2016-12-01

    Full Text Available This work analyzes the impact of new technologies in everyday teaching situations. This is a qualitative research, one study of descriptive case, based on observations of the spaces of the classrooms, the same group of children between June 2013 and April 2015, the 1st, 2nd and 3rd years of Primary Education a Catholic private school, as well as interviews with the regents’ teachers of these classes. We seek to establish links between the acquisition of written language in conventional texts and those in hypertext, as well as understand how to structure the scientific and digital literacy in these areas. In that sense, it was found that these experiences are possible to happen in designed spaces antagonistically to traditional spaces as often, it is less rigid, more flexible, a fact that makes the pleasant atmosphere and at the same time, more accessible, providing an environment sometimes hybrid, in which the dimensions of notebook and tablet coexist and fusion of these opposed pairs of written language acquisition occurs.

  14. Electrochemical biosensors

    Cosnier, Serge

    2015-01-01

    "This is an excellent book on modern electrochemical biosensors, edited by Professor Cosnier and written by leading international experts. It covers state-of-the-art topics of this important field in a clear and timely manner."-Prof. Joseph Wang, UC San Diego, USA  "This book covers, in 13 well-illustrated chapters, the potential of electrochemical methods intimately combined with a biological component for the assay of various analytes of biological and environmental interest. Particular attention is devoted to the description of electrochemical microtools in close contact with a biological cell for exocytosis monitoring and to the use of nanomaterials in the electrochemical biosensor architecture for signal improvement. Interestingly, one chapter describes the concept and design of self-powered biosensors derived from biofuel cells. Each topic is reviewed by experts very active in the field. This timely book is well suited for providing a good overview of current research trends devoted to electrochemical...

  15. Microbial biosensors for environmental monitoring

    David VOGRINC

    2015-12-01

    Full Text Available Microbial biosensors are analytical devices capable of sensing substances in the environment due to the specific biological reaction of the microorganism or its parts. Construction of a microbial biosensor requires knowledge of microbial response to the specific analyte. Linking this response with the quantitative data, using a transducer, is the crucial step in the construction of a biosensor. Regarding the transducer type, biosensors are divided into electrochemical, optical biosensors and microbial fuel cells. The use of the proper configuration depends on the selection of the biosensing element. With the use of transgenic E. coli strains, bioluminescence or fluorescence based biosensors were developed. Microbial fuel cells enable the use of the heterogeneous microbial populations, isolated from wastewater. Different microorganisms are used for different pollutants – pesticides, heavy metals, phenolic compounds, organic waste, etc. Biosensing enables measurement of their concentration and their toxic or genotoxic effects on the microbes. Increasing environmental awareness has contributed to the increase of interest for biomonitoring. Although technologies, such as bioinformatics and genetic engineering, allow us to design complex and efficient microbial biosensors for environmental pollutants, the transfer of the laboratory work to the field still remains a problem to solve.

  16. Implantable enzyme amperometric biosensors.

    Kotanen, Christian N; Moussy, Francis Gabriel; Carrara, Sandro; Guiseppi-Elie, Anthony

    2012-05-15

    The implantable enzyme amperometric biosensor continues as the dominant in vivo format for the detection, monitoring and reporting of biochemical analytes related to a wide range of pathologies. Widely used in animal studies, there is increasing emphasis on their use in diabetes care and management, the management of trauma-associated hemorrhage and in critical care monitoring by intensivists in the ICU. These frontier opportunities demand continuous indwelling performance for up to several years, well in excess of the currently approved seven days. This review outlines the many challenges to successful deployment of chronically implantable amperometric enzyme biosensors and emphasizes the emerging technological approaches in their continued development. The foreign body response plays a prominent role in implantable biotransducer failure. Topics considering the approaches to mitigate the inflammatory response, use of biomimetic chemistries, nanostructured topographies, drug eluting constructs, and tissue-to-device interface modulus matching are reviewed. Similarly, factors that influence biotransducer performance such as enzyme stability, substrate interference, mediator selection and calibration are reviewed. For the biosensor system, the opportunities and challenges of integration, guided by footprint requirements, the limitations of mixed signal electronics, and power requirements, has produced three systems approaches. The potential is great. However, integration along the multiple length scales needed to address fundamental issues and integration across the diverse disciplines needed to achieve success of these highly integrated systems, continues to be a challenge in the development and deployment of implantable amperometric enzyme biosensor systems. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. A chemical sensor and biosensor based totally automated water quality monitor for extended space flight: Step 1

    Smith, Robert S.

    1993-01-01

    The result of a literature search to consider what technologies should be represented in a totally automated water quality monitor for extended space flight is presented. It is the result of the first summer in a three year JOVE project. The next step will be to build a test platform at the Authors' school, St. John Fisher College. This will involve undergraduates in NASA related research. The test flow injection analysis system will be used to test the detection limit of sensors and the performance of sensors in groups. Sensor companies and research groups will be encouraged to produce sensors which are not currently available and are needed for this project.

  18. Technology Area Roadmap for In-Space Propulsion Technologies

    Johnson, Les; Meyer, Michael; Palaszewski, Bryan; Coote, David; Goebel, Dan; White, Harold

    2012-01-01

    The exponential increase of launch system size.and cost.with delta-V makes missions that require large total impulse cost prohibitive. Led by NASA fs Marshall Space Flight Center, a team from government, industry, and academia has developed a flight demonstration mission concept of an integrated electrodynamic (ED) tethered satellite system called PROPEL: \\Propulsion using Electrodynamics.. The PROPEL Mission is focused on demonstrating a versatile configuration of an ED tether to overcome the limitations of the rocket equation, enable new classes of missions currently unaffordable or infeasible, and significantly advance the Technology Readiness Level (TRL) to an operational level. We are also focused on establishing a far deeper understanding of critical processes and technologies to be able to scale and improve tether systems in the future. Here, we provide an overview of the proposed PROPEL mission. One of the critical processes for efficient ED tether operation is the ability to inject current to and collect current from the ionosphere. Because the PROPEL mission is planned to have both boost and deboost capability using a single tether, the tether current must be capable of flowing in both directions and at levels well over 1 A. Given the greater mobility of electrons over that of ions, this generally requires that both ends of the ED tether system can both collect and emit electrons. For example, hollow cathode plasma contactors (HCPCs) generally are viewed as state-of-the-art and high TRL devices; however, for ED tether applications important questions remain of how efficiently they can operate as both electron collectors and emitters. Other technologies will be highlighted that are being investigated as possible alternatives to the HCPC such as Solex that generates a plasma cloud from a solid material (Teflon) and electron emission (only) technologies such as cold-cathode electron field emission or photo-electron beam generation (PEBG) techniques

  19. The Application of Intelligent Building Technologies to Space Hotels

    Fawkes, S.

    This paper reports that over the last few years Intelligent Building technologies have matured and standardised. It compares the functions of command and control systems in future large space facilities such as space hotels to those commonly found in Intelligent Buildings and looks at how Intelligent Building technologies may be applied to space hotels. Many of the functions required in space hotels are the same as those needed in terrestrial buildings. The adaptation of standardised, low cost, Intelligent Building technologies would reduce capital costs and ease development of future space hotels. Other aspects of Intelligent Buildings may also provide useful models for the development and operation of space hotels.

  20. Robotic Fish Technology and Its Applications to Space Mechatronics

    Yamamoto, Ikuo; Shin, Nobuhiro; Oka, Taishi; Matsui, Miki

    2014-01-01

    The authors have developed a shark ray robotic fish based on biomimetic approaches. The paper describes the newly developed robotic fish technology and its application to mechatronics in the space. It is found that robotic fish technology creates not only new underwater robotics, but also the next generation space mechatronics for geological survey of lunar/planets and dust cleaning in the space station.

  1. Space Transportation Materials and Structures Technology Workshop. Volume 2: Proceedings

    Cazier, F.W. Jr.; Gardner, J.E.

    1993-02-01

    The Space Transportation Materials and Structures Technology Workshop was held on September 23-26, 1991, in Newport News, Virginia. The workshop, sponsored by the NASA Office of Space Flight and the NASA Office of Aeronautics and Space Technology, was held to provide a forum for communication within the space materials and structures technology developer and user communities. Workshop participants were organized into a Vehicle Technology Requirements session and three working panels: Materials and Structures Technologies for Vehicle Systems, Propulsion Systems, and Entry Systems. Separate abstracts have been prepared for papers in this report

  2. Technology transfer: The key to successful space engineering education

    Fletcher, L. S.; Page, R. H.

    The 1990s are the threshold of the space revolution for the next century. This space revolution was initiated by space pioneers like Tsiolkovsky, Goddard, and Oberth, who contributed a great deal to the evolution of space exploration, and more importantly, to space education. Recently, space engineering education programs for all ages have been advocated around the world, especially in Asia and Europe, as well as the U.S.A. and the Soviet Union. And yet, although space related technologies are developing rapidly, these technologies are not being incorporated successfully into space education programs. Timely technology transfer is essential to assure the continued education of professionals. This paper reviews the evolution of space engineering education and identifies a number of initiatives which could strengthen space engineering education for the next century.

  3. Technology for Future NASA Missions: Civil Space Technology Initiative (CSTI) and Pathfinder

    1988-01-01

    SEPTEMBER 1988 PACE Space Research and Technology Overview 1 Frederick P. Povinelli Civil Space Technology Initiative 15 Judith H. Ambrus...Peterson Peterson Pierson Pietsch Pilcher Pistole Piszczor Pittian Plotkin Portnoy Poucher Povinelli Povell Pozarovski Priebe Prior Pyle

  4. Energy Storage Technology Development for Space Exploration

    Mercer, Carolyn R.; Jankovsky, Amy L.; Reid, Concha M.; Miller, Thomas B.; Hoberecht, Mark A.

    2011-01-01

    The National Aeronautics and Space Administration is developing battery and fuel cell technology to meet the expected energy storage needs of human exploration systems. Improving battery performance and safety for human missions enhances a number of exploration systems, including un-tethered extravehicular activity suits and transportation systems including landers and rovers. Similarly, improved fuel cell and electrolyzer systems can reduce mass and increase the reliability of electrical power, oxygen, and water generation for crewed vehicles, depots and outposts. To achieve this, NASA is developing non-flow-through proton-exchange-membrane fuel cell stacks, and electrolyzers coupled with low permeability membranes for high pressure operation. The primary advantage of this technology set is the reduction of ancillary parts in the balance-of-plant fewer pumps, separators and related components should result in fewer failure modes and hence a higher probability of achieving very reliable operation, and reduced parasitic power losses enable smaller reactant tanks and therefore systems with lower mass and volume. Key accomplishments over the past year include the fabrication and testing of several robust, small-scale non-flow-through fuel cell stacks that have demonstrated proof-of-concept. NASA is also developing advanced lithium-ion battery cells, targeting cell-level safety and very high specific energy and energy density. Key accomplishments include the development of silicon composite anodes, lithiatedmixed- metal-oxide cathodes, low-flammability electrolytes, and cell-incorporated safety devices that promise to substantially improve battery performance while providing a high level of safety.

  5. EXPRESS Rack Technology for Space Station

    Davis, Ted B.; Adams, J. Brian; Fisher, Edward M., Jr.; Prickett, Guy B.; Smith, Timothy G.

    1999-01-01

    The EXPRESS rack provides accommodations for standard Mid-deck Locker and ISIS drawer payloads on the International Space Station. A design overview of the basic EXPRESS rack and two derivatives, the Human Research Facility and the Habitat Holding Rack, is given in Part I. In Part II, the design of the Solid State Power Control Module (SSPCM) is reviewed. The SSPCM is a programmable and remotely controllable power switching and voltage conversion unit which distributes and protects up to 3kW of 12OVDC and 28VDC power to payloads and rack subsystem components. Part III details the development and testing of a new data storage device, the BRP EXPRESS Memory Unit (BEMU). The BEMU is a conduction-cooled device which operates on 28VDC and is based on Boeing-modified 9GB commercial disk-drive technology. In Part IV results of a preliminary design effort for a rack Passive Damping System (PDS) are reported. The PDS is intended to isolate ISPR-based experiment racks from on-orbit vibration. System performance predictions based on component developmental testing indicate that such a system can provide effective isolation at frequencies of 1 Hz and above.

  6. Medical Applications of Space Light-Emitting Diode Technology--Space Station and Beyond

    Whelan, H.T.; Houle, J.M.; Donohoe, D.L.; Bajic, D.M.; Schmidt, M.H.; Reichert, K.W.; Weyenberg, G.T.; Larson, D.L.; Meyer, G.A.; Caviness, J.A.

    1999-06-01

    Space light-emitting diode (LED) technology has provided medicine with a new tool capable of delivering light deep into tissues of the body, at wavelengths which are biologically optimal for cancer treatment and wound healing. This LED technology has already flown on Space Shuttle missions, and shows promise for wound healing applications of benefit to Space Station astronauts.

  7. Media Spaces, Places and Palpable Technologies

    Kristensen, Margit; Kyng, Morten

    2006-01-01

    of these prototypes form what can be termed as media spaces - but rise questions to the traditional understanding of the media space concept - since the emergency response media spaces are not ‘set up' in predefined physical settings, do allow use of a range of (not necessarily predefined) media, and the people...

  8. Proposal for a United Nations Basic Space Technology Initiative

    Balogh, Werner

    Putting space technology and its applications to work for sustainable economic and social development is the primary objective of the United Nations Programme on Space Applications, launched in 1971. A specific goal for achieving this objective is to establish a sustainable national space capacity. The traditional line of thinking has supported a logical progression from building capacity in basic space science, to using space applications and finally - possibly - to establishing indigenous space technology capabilities. The experience in some countries suggests that such a strict line of progression does not necessarily hold true and that priority given to the establishment of early indigenous space technology capabilities may contribute to promoting the operational use of space applications in support of sustainable economic and social development. Based on these findings and on the experiences with the United Nations Basic Space Science Initiative (UNBSSI) as well as on a series of United Nations/International Academy of Astronautics Workshops on Small Satellites in the Service of Developing Countries, the United Nations Office for Outer Space Affairs (UNOOSA) is considering the launch of a dedicated United Nations Basic Space Technology Initiative (UNBSTI). The initiative would aim to contribute to capacity building in basic space technology and could include, among other relevant fields, activities related to the space and ground segments of small satellites and their applications. It would also provide an international framework for enhancing cooperation between all interested actors, facilitate the exchange of information on best practices, and contribute to standardization efforts. It is expected that these activities would advance the operational use of space technology and its applications in an increasing number of space-using countries and emerging space nations. The paper reports on these initial considerations and on the potential value-adding role

  9. Space Station Freedom - Accommodation for technology R&D

    Holt, Alan C.

    1989-01-01

    The paper examines the features of the accommodation equipment designed for the candidate technology payloads of the Space Station, which include magnetic plasma thruster systems and a hypothetical advanced electromagnetic propulsion system utilizing high-temperature superconductivity materials. The review of the accommodation-equipment concepts supports the assumption that some propulsion technologies can be tested on the Space Station while being attached externally to the station's truss structure. For testing technologies with inherent operation or performance hazards, space platforms and smaller free-flyers coordinated with the Space Station can be used. Diagrams illustrating typical accommodation equipment configurations are included.

  10. A Biosensor-CMOS Platform and Integrated Readout Circuit in 0.18-μm CMOS Technology for Cancer Biomarker Detection

    Abdulaziz Alhoshany

    2017-08-01

    Full Text Available This paper presents a biosensor-CMOS platform for measuring the capacitive coupling of biorecognition elements. The biosensor is designed, fabricated, and tested for the detection and quantification of a protein that reveals the presence of early-stage cancer. For the first time, the spermidine/spermine N1 acetyltransferase (SSAT enzyme has been screened and quantified on the surface of a capacitive sensor. The sensor surface is treated to immobilize antibodies, and the baseline capacitance of the biosensor is reduced by connecting an array of capacitors in series for fixed exposure area to the analyte. A large sensing area with small baseline capacitance is implemented to achieve a high sensitivity to SSAT enzyme concentrations. The sensed capacitance value is digitized by using a 12-bit highly digital successive-approximation capacitance-to-digital converter that is implemented in a 0.18 μm CMOS technology. The readout circuit operates in the near-subthreshold regime and provides power and area efficient operation. The capacitance range is 16.137 pF with a 4.5 fF absolute resolution, which adequately covers the concentrations of 10 mg/L, 5 mg/L, 2.5 mg/L, and 1.25 mg/L of the SSAT enzyme. The concentrations were selected as a pilot study, and the platform was shown to demonstrate high sensitivity for SSAT enzymes on the surface of the capacitive sensor. The tested prototype demonstrated 42.5 μS of measurement time and a total power consumption of 2.1 μW.

  11. A Biosensor-CMOS Platform and Integrated Readout Circuit in 0.18-μm CMOS Technology for Cancer Biomarker Detection.

    Alhoshany, Abdulaziz; Sivashankar, Shilpa; Mashraei, Yousof; Omran, Hesham; Salama, Khaled N

    2017-08-23

    This paper presents a biosensor-CMOS platform for measuring the capacitive coupling of biorecognition elements. The biosensor is designed, fabricated, and tested for the detection and quantification of a protein that reveals the presence of early-stage cancer. For the first time, the spermidine/spermine N1 acetyltransferase (SSAT) enzyme has been screened and quantified on the surface of a capacitive sensor. The sensor surface is treated to immobilize antibodies, and the baseline capacitance of the biosensor is reduced by connecting an array of capacitors in series for fixed exposure area to the analyte. A large sensing area with small baseline capacitance is implemented to achieve a high sensitivity to SSAT enzyme concentrations. The sensed capacitance value is digitized by using a 12-bit highly digital successive-approximation capacitance-to-digital converter that is implemented in a 0.18 μm CMOS technology. The readout circuit operates in the near-subthreshold regime and provides power and area efficient operation. The capacitance range is 16.137 pF with a 4.5 fF absolute resolution, which adequately covers the concentrations of 10 mg/L, 5 mg/L, 2.5 mg/L, and 1.25 mg/L of the SSAT enzyme. The concentrations were selected as a pilot study, and the platform was shown to demonstrate high sensitivity for SSAT enzymes on the surface of the capacitive sensor. The tested prototype demonstrated 42.5 μS of measurement time and a total power consumption of 2.1 μW.

  12. A Biosensor-CMOS Platform and Integrated Readout Circuit in 0.18-μm CMOS Technology for Cancer Biomarker Detection

    Alhoshany, Abdulaziz

    2017-08-23

    This paper presents a biosensor-CMOS platform for measuring the capacitive coupling of biorecognition elements. The biosensor is designed, fabricated, and tested for the detection and quantification of a protein that reveals the presence of early-stage cancer. For the first time, the spermidine/spermine N1 acetyltransferase (SSAT) enzyme has been screened and quantified on the surface of a capacitive sensor. The sensor surface is treated to immobilize antibodies, and the baseline capacitance of the biosensor is reduced by connecting an array of capacitors in series for fixed exposure area to the analyte. A large sensing area with small baseline capacitance is implemented to achieve a high sensitivity to SSAT enzyme concentrations. The sensed capacitance value is digitized by using a 12-bit highly digital successive-approximation capacitance-to-digital converter that is implemented in a 0.18 μm CMOS technology. The readout circuit operates in the near-subthreshold regime and provides power and area efficient operation. The capacitance range is 16.137 pF with a 4.5 fF absolute resolution, which adequately covers the concentrations of 10 mg/L, 5 mg/L, 2.5 mg/L, and 1.25 mg/L of the SSAT enzyme. The concentrations were selected as a pilot study, and the platform was shown to demonstrate high sensitivity for SSAT enzymes on the surface of the capacitive sensor. The tested prototype demonstrated 42.5 μS of measurement time and a total power consumption of 2.1 μW.

  13. A Biosensor-CMOS Platform and Integrated Readout Circuit in 0.18-μm CMOS Technology for Cancer Biomarker Detection

    Alhoshany, Abdulaziz; Sivashankar, Shilpa; Mashraei, Yousof; Omran, Hesham; Salama, Khaled N.

    2017-01-01

    This paper presents a biosensor-CMOS platform for measuring the capacitive coupling of biorecognition elements. The biosensor is designed, fabricated, and tested for the detection and quantification of a protein that reveals the presence of early-stage cancer. For the first time, the spermidine/spermine N1 acetyltransferase (SSAT) enzyme has been screened and quantified on the surface of a capacitive sensor. The sensor surface is treated to immobilize antibodies, and the baseline capacitance of the biosensor is reduced by connecting an array of capacitors in series for fixed exposure area to the analyte. A large sensing area with small baseline capacitance is implemented to achieve a high sensitivity to SSAT enzyme concentrations. The sensed capacitance value is digitized by using a 12-bit highly digital successive-approximation capacitance-to-digital converter that is implemented in a 0.18 μm CMOS technology. The readout circuit operates in the near-subthreshold regime and provides power and area efficient operation. The capacitance range is 16.137 pF with a 4.5 fF absolute resolution, which adequately covers the concentrations of 10 mg/L, 5 mg/L, 2.5 mg/L, and 1.25 mg/L of the SSAT enzyme. The concentrations were selected as a pilot study, and the platform was shown to demonstrate high sensitivity for SSAT enzymes on the surface of the capacitive sensor. The tested prototype demonstrated 42.5 μS of measurement time and a total power consumption of 2.1 μW.

  14. Advanced Space Radiation Detector Technology Development

    Wrbanek, John D.; Wrbanek, Susan Y.; Fralick, Gustave C.

    2013-01-01

    The advanced space radiation detector development team at the NASA Glenn Research Center (GRC) has the goal of developing unique, more compact radiation detectors that provide improved real-time data on space radiation. The team has performed studies of different detector designs using a variety of combinations of solid-state detectors, which allow higher sensitivity to radiation in a smaller package and operate at lower voltage than traditional detectors. Integration of multiple solid-state detectors will result in an improved detector system in comparison to existing state-of-the-art instruments for the detection and monitoring of the space radiation field for deep space and aerospace applications.

  15. Overview of space nuclear technologies and the American Nuclear Society

    Singleterry, R.C. Jr.

    2000-01-01

    The American Nuclear Society (ANS) has seen an aspect of the universe where nuclear technology is the best energy source available for power, transportation, etc. The National Aeronautics and Space Administration (NASA) has been exploiting this aspect of the universe by sending machines and humans into it and exploring, colonizing, industrializing, developing, inhabiting, etc. Space is the final frontier, and nuclear technology is the best suited for today's or the next century's space exploration and development. Many aspects of nuclear technology and its uses in space will be needed. ANS encompasses these and many more aspects of nuclear technology, and all have some role to play in the exploration and development of space. It should be ANS's intent to be an advisory body to NASA on the nuclear aspects of space exploration

  16. Research and Technology 1996: Innovation in Time and Space

    1996-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1996 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities.

  17. A Technology Plan for Enabling Commercial Space Business

    Lyles, Garry M.

    1997-01-01

    The National Aeronautics and Space Administration's (NASA) Advanced Space Transportation Program is a customer driven, focused technology program that supports the NASA Strategic Plan and considers future commercial space business projections. The initial cycle of the Advanced Space Transportation Program implementation planning was conducted from December 1995 through February 1996 and represented increased NASA emphasis on broad base technology development with the goal of dramatic reductions in the cost of space transportation. The second planning cycle, conducted in January and February 1997, updated the program implementation plan based on changes in the external environment, increased maturity of advanced concept studies, and current technology assessments. The program has taken a business-like approach to technology development with a balanced portfolio of near, medium, and long-term strategic targets. Strategic targets are influenced by Earth science, space science, and exploration objectives as well as commercial space markets. Commercial space markets include those that would be enhanced by lower cost transportation as well as potential markets resulting in major increases in space business induced by reductions in transportation cost. The program plan addresses earth-to-orbit space launch, earth orbit operations and deep space systems. It also addresses all critical transportation system elements; including structures, thermal protection systems, propulsion, avionics, and operations. As these technologies are matured, integrated technology flight experiments such as the X-33 and X-34 flight demonstrator programs support near-term (one to five years) development or operational decisions. The Advanced Space Transportation Program and the flight demonstrator programs combine business planning, ground-based technology demonstrations and flight demonstrations that will permit industry and NASA to commit to revolutionary new space transportation systems

  18. Space 2035: Technology, Transparency, and Trusted Immunity

    2010-02-17

    12 Figure 2: Maglev -Assisted RLV Concepts .................................................................................. 14...reusable launch vehicles (RLVs). 12, 13 14 Figure 2: Maglev -Assisted RLV Concepts 14 By 2035, several innovative concepts for space...transportation may emerge. These include magnetically-levitated and assisted ( maglev ) RLVs; a novel Space Pier concept, which comprises a series of

  19. Application of SDI technology in space propulsion

    Klein, A.J.

    1992-01-01

    Numerous technologies developed by the DOD within the SDI program are now available for adaptation to the requirements of commercial spacecraft; SDI has accordingly organized the Technology Applications Information System data base, which contains nearly 2000 nonproprietary abstracts on SDI technology. Attention is here given to such illustrative systems as hydrogen arcjets, ammonia arcjets, ion engines, SSTO launch vehicles, gel propellants, lateral thrusters, pulsed electrothermal thrusters, laser-powered rockets, and nuclear propulsion

  20. Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products.

    Kho, Dan T; Johnson, Rebecca H; O'Carroll, Simon J; Angel, Catherine E; Graham, E Scott

    2017-09-21

    Herein we demonstrate the sensitive nature of human blood-brain barrier (BBB) endothelial cells to sodium azide and its gaseous product. Sodium azide is known to be acutely cytotoxic at low millimolar concentrations, hence its use as a biological preservative (e.g., in antibodies). Loss of barrier integrity was noticed in experiments using Electric Cell-substrate Impedance Sensing (ECIS) biosensor technology, to measure endothelial barrier integrity continuously in real-time. Initially the effect of sodium azide was observed as an artefact where it was present in antibodies being employed in neutralisation experiments. This was confirmed where antibody clones that were azide-free did not mediate loss of barrier function. A delayed loss of barrier function in neighbouring wells implied the influence of a liberated gaseous product. ECIS technology demonstrated that the BBB endothelial cells had a lower level of direct sensitivity to sodium azide of ~3 µM. Evidence of gaseous toxicity was consistently observed at 30 µM and above, with disrupted barrier function and cell death in neighbouring wells. We highlight the ability of this cellular biosensor technology to reveal both the direct and gaseous toxicity mediated by sodium azide. The sensitivity and temporal dimension of ECIS technology was instrumental in these observations. These findings have substantial implications for the wide use of sodium azide in biological reagents, raising issues of their application in live-cell assays and with regard to the protection of the user. This research also has wider relevance highlighting the sensitivity of brain endothelial cells to a known mitochondrial disruptor. It is logical to hypothesise that BBB endothelial dysfunction due to mitochondrial dys-regulation could have an important but underappreciated role in a range of neurological diseases.

  1. MMIC technology for advanced space communications systems

    Downey, A. N.; Connolly, D. J.; Anzic, G.

    The current NASA program for 20 and 30 GHz monolithic microwave integrated circuit (MMIC) technology is reviewed. The advantages of MMIC are discussed. Millimeter wavelength MMIC applications and technology for communications systems are discussed. Passive and active MMIC compatible components for millimeter wavelength applications are investigated. The cost of a millimeter wavelength MMIC's is projected.

  2. MMIC technology for advanced space communications systems

    Downey, A. N.; Connolly, D. J.; Anzic, G.

    1984-01-01

    The current NASA program for 20 and 30 GHz monolithic microwave integrated circuit (MMIC) technology is reviewed. The advantages of MMIC are discussed. Millimeter wavelength MMIC applications and technology for communications systems are discussed. Passive and active MMIC compatible components for millimeter wavelength applications are investigated. The cost of a millimeter wavelength MMIC's is projected.

  3. Space Internet-Embedded Web Technologies Demonstration

    Foltz, David A.

    2001-01-01

    The NASA Glenn Research Center recently demonstrated the ability to securely command and control space-based assets by using the Internet and standard Internet Protocols (IP). This is a significant accomplishment because future NASA missions will benefit by using Internet standards-based protocols. The benefits include reduced mission costs and increased mission efficiency. The Internet-Based Space Command and Control System Architecture demonstrated at the NASA Inspection 2000 event proved that this communications architecture is viable for future NASA missions.

  4. Space assets, technology and services in support of energy policy

    Vasko, C. A.; Adriaensen, M.; Bretel, A.; Duvaux-Bechon, I.; Giannopapa, C. G.

    2017-09-01

    Space can be used as a tool by decision and policy makers in developing, implementing and monitoring various policy areas including resource management, environment, transport, security and energy. This paper focuses on the role of space for the energy policy. Firstly, the paper summarizes the European Union's (EU) main objectives in energy policy enclosed in the Energy Strategy 2020-2030-2050 and demonstrates how space assets can contribute to achieving those objectives. Secondly, the paper addresses how the European Space Agency (ESA) has established multiple initiatives and programs that directly finance the development of space assets, technology and applications that deliver services in support of the EU energy policy and sector. These efforts should be continued and strengthened in order to overcome identified technological challenges. The use of space assets, technology and applications, can help achieve the energy policy objectives for the next decades.

  5. Development of Biosensors From Graphene

    高瑞红; 孙红; 李霄寒; 于冲

    2017-01-01

    Graphene's success has stimulated great interest and research in the synthesis and characterization of graphene -like 2D materials, single and few -atom -thick layers of van der Waals materials, which show fascinating and technologically useful properties.This review presents an overview of recent electrochemical sensors and biosensors based on graphene and on graphene-like 2D materials.

  6. In-Space Structural Assembly: Applications and Technology

    Belvin, W. Keith; Doggett, Bill R.; Watson, Judith J.; Dorsey, John T.; Warren, Jay; Jones, Thomas C.; Komendera, Erik E.; Mann, Troy O.; Bowman, Lynn

    2016-01-01

    As NASA exploration moves beyond earth's orbit, the need exists for long duration space systems that are resilient to events that compromise safety and performance. Fortunately, technology advances in autonomy, robotic manipulators, and modular plug-and-play architectures over the past two decades have made in-space vehicle assembly and servicing possible at acceptable cost and risk. This study evaluates future space systems needed to support scientific observatories and human/robotic Mars exploration to assess key structural design considerations. The impact of in-space assembly is discussed to identify gaps in structural technology and opportunities for new vehicle designs to support NASA's future long duration missions.

  7. Education and Outreach on Space Sciences and Technologies in Taiwan

    Tiger Liu, Jann-Yeng; Chen, hao-Yen; Lee, I.-Te

    2014-05-01

    The Ionospheric Radio Science Laboratory (IRSL) at Institute of Space Science, National Central University in Taiwan has been conducting a program for public outreach educations on space science by giving lectures, organizing camps, touring exhibits, and experiencing hand-on experiments to elementary school, high school, and college students as well as general public since 1991. The program began with a topic of traveling/living in space, and was followed by space environment, space mission, and space weather monitoring, etc. and a series of course module and experiment (i.e. experiencing activity) module was carried out. For past decadal, the course modules have been developed to cover the space environment of the Sun, interplanetary space, and geospace, as well as the space technology of the rocket, satellite, space shuttle (plane), space station, living in space, observing the Earth from space, and weather observation. Each course module highlights the current status and latest new finding as well as discusses 1-3 key/core issues/concepts and equip with 2-3 activity/experiment modules to make students more easily to understand the topics/issues. Regarding the space technologies, we focus on remote sensing of Earth's surface by FORMOSAT-2 and occultation sounding by FORMOSAT-3/COSMIC of Taiwan space mission. Moreover, scientific camps are given to lead students a better understanding and interesting on space sciences/ technologies. Currently, a visualized image projecting system, Dagik Earth, is developed to demonstrate the scientific results on a sphere together with the course modules. This system will dramatically improve the educational skill and increase interests of participators.

  8. NASA Space Technology Roadmaps and Priorities: Restoring NASA's Technological Edge and Paving the Way for a New Era in Space

    2012-01-01

    Success in executing future NASA space missions will depend on advanced technology developments that should already be underway. It has been years since NASA has had a vigorous, broad-based program in advanced space technology development, and NASA's technology base is largely depleted. As noted in a recent National Research Council report on the U.S. civil space program: Future U.S. leadership in space requires a foundation of sustained technology advances that can enable the development of more capable, reliable, and lower-cost spacecraft and launch vehicles to achieve space program goals. A strong advanced technology development foundation is needed also to enhance technology readiness of new missions, mitigate their technological risks, improve the quality of cost estimates, and thereby contribute to better overall mission cost management. Yet financial support for this technology base has eroded over the years. The United States is now living on the innovation funded in the past and has an obligation to replenish this foundational element. NASA has developed a draft set of technology roadmaps to guide the development of space technologies under the leadership of the NASA Office of the Chief Technologist. The NRC appointed the Steering Committee for NASA Technology Roadmaps and six panels to evaluate the draft roadmaps, recommend improvements, and prioritize the technologies within each and among all of the technology areas as NASA finalizes the roadmaps. The steering committee is encouraged by the initiative NASA has taken through the Office of the Chief Technologist (OCT) to develop technology roadmaps and to seek input from the aerospace technical community with this study.

  9. Miniature Biosensor with Health Risk Assessment Feedback

    Hanson, Andrea; Downs, Meghan; Kalogera, Kent; Buxton, Roxanne; Cooper, Tommy; Cooper, Alan; Cooper, Ross

    2016-01-01

    Heart rate (HR) monitoring is a medical requirement during exercise on the International Space Station (ISS), fitness tests, and extravehicular activity (EVA); however, NASA does not currently have the technology to consistently and accurately monitor HR and other physiological data during these activities. Performance of currently available HR monitor technologies is dependent on uninterrupted contact with the torso and are prone to data drop-out and motion artifact. Here, we seek an alternative to the chest strap and electrode based sensors currently in use on ISS today. This project aims to develop a high performance, robust earbud based biosensor with focused efforts on improved HR data quality during exercise or EVA. A health risk assessment algorithm will further advance the goals of autonomous crew health care for exploration missions.

  10. Technology Development and Demonstration Concepts for the Space Elevator

    Smitherman, David V., Jr.

    2004-01-01

    During the 1990s several discoveries and advances in the development of carbon nano-tube (CNT) materials indicated that material strengths many times greater than common high-strength composite materials might be possible. Progress in the development of this material led to renewed interest in the space elevator concept for construction of a tether structure from the surface of the Earth through a geostationary orbit (GEO) and thus creating a new approach to Earth-to-orbit transportation infrastructures. To investigate this possibility the author, in 1999, managed for NASA a space elevator work:hop at the Marshall Space Flight Center to explore the potential feasibility of space elevators in the 21 century, and to identify the critical technologies and demonstration missions needed to make development of space elevators feasible. Since that time, a NASA Institute for Advanced Concepts (NIAC) funded study of the Space Elevator proposed a concept for a simpler first space elevator system using more near-term technologies. This paper will review some of the latest ideas for space elevator development, the critical technologies required, and some of the ideas proposed for demonstrating the feasibility for full-scale development of an Earth to GEO space elevator. Critical technologies include CNT composite materials, wireless power transmission, orbital object avoidance, and large-scale tether deployment and control systems. Numerous paths for technology demonstrations have been proposed utilizing ground experiments, air structures. LEO missions, the space shuttle, the international Space Station, GEO demonstration missions, demonstrations at the lunar L1 or L2 points, and other locations. In conclusion, this paper finds that the most critical technologies for an Earth to GEO space elevator include CNT composite materials development and object avoidance technologies; that lack of successful development of these technologies need not preclude continued development of

  11. Technology for the Stars: Extending Our Reach. [Research and Technology: 1995 Annual Report of the Marshall Space Flight Center.

    1996-01-01

    Marshall Space Flight Center's (MSFC's) Advanced Studies, Research, Technology, and Technology Transfer projects are summarized in this report. The focus of the report is on the three spotlights at MSFC in 1995: space transportation technology, microgravity research, and technology transfer.

  12. Space technology transfer to developing countries: opportunities and difficulties

    Leloglu, U. M.; Kocaoglan, E.

    Space technology, with its implications on science, economy and security, is mostly chosen as one of the priority areas for technological development by developing countries. Most nations aspiring to begin playing in the space league prefer technology transfer programs as a first step. Decreasing initial costs by small satellite technology made this affordable for many countries. However, there is a long way from this first step to establishment of a reliable space industry that can both survive in the long term with limited financial support from the government and meet national needs. This is especially difficult when major defense companies of industrialized countries are merging to sustain their competitiveness. The prerequisites for the success are implementation of a well-planned space program and existence of industrialization that can support basic testing and manufacturing activities and supply qualified manpower. In this study, the difficulties to be negotiated and the vicious circles to be broken for latecomers, that is, developing countries that invest on space technologies are discussed. Especially, difficulties in the technology transfer process itself, brain drain from developing countries to industrialized countries, strong competition from big space companies for domestic needs, costs of establishing and maintaining an infrastructure necessary for manufacturing and testing activities, and finally, the impact of export control will be emphasized. We will also try to address how and to what extent collaboration can solve or minimize these problems. In discussing the ideas mentioned above, lessons learned from the BILSAT Project, a technology transfer program from the UK, will be referred.

  13. Telerobotic technology for nuclear and space applications

    Herndon, J.N.; Hamel, W.R.

    1987-03-01

    Telerobotic development efforts at Oak Ridge National Laboratory are extensive and relatively diverse. Current efforts include development of a prototype space telerobot system for the NASA Langley Research Center and development and large-scale demonstration of nuclear fuel cycle teleoperators in the Consolidated Fuel Reprocessing Program. This paper presents an overview of the efforts in these major programs. 10 refs., 8 figs

  14. Development of space foods using radiation technology

    Lee, Ju-Woon; Byun, Myung-Woo; Kim, Jae-Hun; Song, Beom-Suk; Choi, Jong-IL; Park, Jin-Kyu; Park, Jae-Nam; Han, In-Jun

    2008-07-01

    Four Korean food items (Kimchi, ready-to-eat fermented vegetable; Ramen, ready-to-cook noodles; Nutrition bar, ready-to-eat raw grain bar; Sujeonggwa, cinnamon beverage) have been developed as space foods by the application of high-dose gamma irradiation. All Korean space foods were certificated for use in space flight conditions during 30 days by the Russian Institute of Biomedical Problems. Establishment of research protocols on muscle atrophy mechanism using two-dimensional electrophoresis and various blotting analyses are conducted. And two bio-active molecules that potentially play an preventive role of muscle atrophy are uncovered. Integrative protocols linking between the effect of bio-active molecules and treadmill exercise for muscle atrophy inhibition are established. Reduction in body temperature and heartbeat rate were monitored after HIT injection to mice was conducted. Development of Korean astronaut preferred flavoring for space food was conducted to reduced atherogenic index (AI) than butter fat. The spread added honey and pineapple essence was preferred spreadability and overall flavor by sensory evaluation. Flavor was affected by irradiation source (γ-ray or electron beam) or irradiation dosage (10, 20, 30, 40 and 50 kGy) using electronic nose system an space foods using gamma irradiation pH of porridge was mostly stable and pH increased. Most of TBARS value was generally low, and there wasn't any significant difference. Consistency, viscosity, and firmness was higher in round rice porridge and half rice porridge than in rice powder porridge, and increase in added water amount led to decrease of all textural properties

  15. Development of space foods using radiation technology

    Lee, Ju-Woon; Byun, Myung-Woo; Kim, Jae-Hun; Song, Beom-Suk; Choi, Jong-IL; Park, Jin-Kyu; Park, Jae-Nam; Han, In-Jun

    2008-07-15

    Four Korean food items (Kimchi, ready-to-eat fermented vegetable; Ramen, ready-to-cook noodles; Nutrition bar, ready-to-eat raw grain bar; Sujeonggwa, cinnamon beverage) have been developed as space foods by the application of high-dose gamma irradiation. All Korean space foods were certificated for use in space flight conditions during 30 days by the Russian Institute of Biomedical Problems. Establishment of research protocols on muscle atrophy mechanism using two-dimensional electrophoresis and various blotting analyses are conducted. And two bio-active molecules that potentially play an preventive role of muscle atrophy are uncovered. Integrative protocols linking between the effect of bio-active molecules and treadmill exercise for muscle atrophy inhibition are established. Reduction in body temperature and heartbeat rate were monitored after HIT injection to mice was conducted. Development of Korean astronaut preferred flavoring for space food was conducted to reduced atherogenic index (AI) than butter fat. The spread added honey and pineapple essence was preferred spreadability and overall flavor by sensory evaluation. Flavor was affected by irradiation source ({gamma}-ray or electron beam) or irradiation dosage (10, 20, 30, 40 and 50 kGy) using electronic nose system an space foods using gamma irradiation pH of porridge was mostly stable and pH increased. Most of TBARS value was generally low, and there wasn't any significant difference. Consistency, viscosity, and firmness was higher in round rice porridge and half rice porridge than in rice powder porridge, and increase in added water amount led to decrease of all textural properties.

  16. Space Technology and Applications International Forum -1999. Proceedings

    El-Genk, M.S.

    1999-01-01

    These proceedings represent papers presented at the 1999 Space Technology and Applications International Forum (STAIF-99). This is a large conference in terms of the number of hosted technical sessions and the technical papers presented. This year's theme, ''Opportunities and Challenges for the New Millenium,'' covered a broad spectrum of topics in space science and technology that spans the range from basic research, such as thermophysics in microgravity and breakthrough propulsion physics, to the most recent advances in space power and propulsion, space exploration and commercialization, next generation launch systems, and the international effort to deploy and assemble the international space station. STAIF-99 was co-sponsored by the United States Department of Energy. The two-volume proceedings includes 253 articles, out of which 28 have been abstracted for the Energy,Science and Technology database

  17. Recent Progress in Space-Division Multiplexed Transmission Technologies

    Morioka, Toshio

    2013-01-01

    Recent development of transmission technologies based on space-division multiplexing is described with future perspectives including a recent achievement of one Pb/s transmission in a single strand of fiber....

  18. Distributed Space System Technology Demonstrations with the Emerald Nanosatellite

    Twiggs, Robert

    2002-01-01

    A viewgraph presentation of Distributed Space System Technologies utilizing the Emerald Nanosatellite is shown. The topics include: 1) Structure Assembly; 2) Emerald Mission; 3) Payload and Mission Operations; 4) System and Subsystem Description; and 5) Safety Integration and Testing.

  19. Enhanced surrogate models for statistical design exploiting space mapping technology

    Koziel, Slawek; Bandler, John W.; Mohamed, Achmed S.

    2005-01-01

    We present advances in microwave and RF device modeling exploiting Space Mapping (SM) technology. We propose new SM modeling formulations utilizing input mappings, output mappings, frequency scaling and quadratic approximations. Our aim is to enhance circuit models for statistical analysis...

  20. New technology innovations with potential for space applications

    Krishen, Kumar

    2008-07-01

    Human exploration and development of space is being pursued by spacefaring nations to explore, use, and enable the development of space and expand the human experience there. The goals include: increasing human knowledge of nature's processes using the space environment; exploring and settling the solar system; achieving routine space travel; and enriching life on Earth through living and working in space. A crucial aspect of future space missions is the development of infrastructure to optimize safety, productivity, and costs. A major component of mission execution is operations management. NASA's International Space Station is providing extensive experience in both infrastructure and operations. In view of this, a vigorously organized approach is needed to implement successful space-, planet-, and ground-based research and operations that entails wise and efficient use of technical and human resources. Many revolutionary technologies being pursued by researchers and technologists may be vital in making space missions safe, reliable, cost-effective, and productive. These include: ionic polymer-metal composite technology; solid-state lasers; time-domain sensors and communication systems; high-temperature superconductivity; nanotechnology; variable specific impulse magneto plasma rocket; fuzzy logic; wavelet technology; and neural networks. An overview of some of these will be presented, along with their application to space missions.

  1. SPace weather applications in a technology-dependent society

    Ngwira, C. M.

    2017-12-01

    Space weather can adversely key technology assets, such as, high-voltage electric power transmission grids, oil and gas pipelines, and communications systems that are critical to national security and economy. However, the term of "space weather" is not well known in our society. This presentation will introduce key concepts related to the space weather problem and show how space weather impacts our everyday life. The goal is to promote awareness among the general public. Also, this presentation will highlight how space weather is being used to promote STEM education for community college students through the NASA internship program.

  2. Ghana Space Science and Technology Institute (GSSTI) - Annual Report 2015

    2015-01-01

    The Ghana Space Science and Technology Institute (GSSTI) of the Ghana Atomic Energy Commission was established to exploit space science and technology for socio-economic development of Ghana. The report gives the structure of GSSTI and the detailed activities of the year. Various activities include: training and seminars, projects and workshops. Publications and their abstracts are also listed. The report also highlights some of the challenges, provides some recommendations and points to some expectation for the following year.

  3. Space Technology and Earth System Science

    Habib, Shahid

    2011-01-01

    Science must continue to drive the technology development. Partnering and Data Sharing among nations is very important to maximize the cost benefits of such investments Climate changes and adaptability will be a big challenge for the next several decades (1) Natural disasters frequency and locations (2) Economic and social impact can be global and (3) Water resources and management.

  4. National Space Transportation System (NSTS) technology needs

    Winterhalter, David L.; Ulrich, Kimberly K.

    1990-01-01

    The National Space Transportation System (NSTS) is one of the Nation's most valuable resources, providing manned transportation to and from space in support of payloads and scientific research. The NSTS program is currently faced with the problem of hardware obsolescence, which could result in unacceptable schedule and cost impacts to the flight program. Obsolescence problems occur because certain components are no longer being manufactured or repair turnaround time is excessive. In order to achieve a long-term, reliable transportation system that can support manned access to space through 2010 and beyond, NASA must develop a strategic plan for a phased implementation of enhancements which will satisfy this long-term goal. The NSTS program has initiated the Assured Shuttle Availability (ASA) project with the following objectives: eliminate hardware obsolescence in critical areas, increase reliability and safety of the vehicle, decrease operational costs and turnaround time, and improve operational capability. The strategy for ASA will be to first meet the mandatory needs - keep the Shuttle flying. Non-mandatory changes that will improve operational capability and enhance performance will then be considered if funding is adequate. Upgrade packages should be developed to install within designated inspection periods, grouped in a systematic approach to reduce cost and schedule impacts, and allow the capability to provide a Block 2 Shuttle (Phase 3).

  5. Critical Technologies for the Development of Future Space Elevator Systems

    Smitherman, David V., Jr.

    2005-01-01

    A space elevator is a tether structure extending through geosynchronous earth orbit (GEO) to the surface of the earth. Its center of mass is in GEO such that it orbits the earth in sync with the earth s rotation. In 2004 and 2005, the NASA Marshall Space Flight Center and the Institute for Scientific Research, Inc. worked under a cooperative agreement to research the feasibility of space elevator systems, and to advance the critical technologies required for the future development of space elevators for earth to orbit transportation. The discovery of carbon nanotubes in the early 1990's was the first indication that it might be possible to develop materials strong enough to make space elevator construction feasible. This report presents an overview of some of the latest NASA sponsored research on space elevator design, and the systems and materials that will be required to make space elevator construction possible. In conclusion, the most critical technology for earth-based space elevators is the successful development of ultra high strength carbon nanotube reinforced composites for ribbon construction in the 1OOGPa range. In addition, many intermediate technology goals and demonstration missions for the space elevator can provide significant advancements to other spaceflight and terrestrial applications.

  6. JPRS Report, Science & Technology, USSR: Space.

    1988-08-17

    Half-life, years Specific Heat Release W/hr Plutonium-238 87.5 0.46 Curium-244 18.4 2.8 Curium-242 0.45 120 Polonium - 210 0.38 144 Polonium - 210 ...begun train- ing a year before the flight. The prospective space travelers had to be trained to stay in a special capsule and to use nozzles for food ...conditions of extended weight- lessness. On command, the animals are given food and water, waste is removed, and day/night conditions are regulated

  7. Overview of NASA Power Technologies for Space and Aero Applications

    Beach, Raymond F.

    2014-01-01

    To achieve the ambitious goals that NASA has outlined for the next decades considerable development of power technology will be necessary. This presentation outlines the development objectives for both the space and aero applications. It further looks at the various power technologies that support these objectives and examines drivers that will be a driving force for future development.

  8. Space station high gain antenna concept definition and technology development

    Wade, W. D.

    1972-01-01

    The layout of a technology base is reported from which a mechanically gimballed, directional antenna can be developed to support a manned space station proposed for the late 1970's. The effort includes the concept definition for the antenna assembly, an evaluation of available technology, the design of critical subassemblies and the design of critical subassembly tests.

  9. Technology assessment of advanced automation for space missions

    1982-01-01

    Six general classes of technology requirements derived during the mission definition phase of the study were identified as having maximum importance and urgency, including autonomous world model based information systems, learning and hypothesis formation, natural language and other man-machine communication, space manufacturing, teleoperators and robot systems, and computer science and technology.

  10. Technology Investment Agendas to Expand Human Space Futures

    Sherwood, Brent

    2012-01-01

    The paper develops four alternative core-technology advancement specifications, one for each of the four strategic goal options for government investment in human space flight. Already discussed in the literature, these are: Explore Mars; Settle the Moon; accelerate commercial development of Space Passenger Travel; and enable industrial scale-up of Space Solar Power for Earth. In the case of the Explore Mars goal, the paper starts with the contemporary NASA accounting of ?55 Mars-enabling technologies. The analysis decomposes that technology agenda into technologies applicable only to the Explore Mars goal, versus those applicable more broadly to the other three options. Salient technology needs of all four options are then elaborated to a comparable level of detail. The comparison differentiates how technologies or major developments that may seem the same at the level of budget lines or headlines (e.g., heavy-lift Earth launch) would in fact diverge widely if developed in the service of one or another of the HSF goals. The paper concludes that the explicit choice of human space flight goal matters greatly; an expensive portfolio of challenging technologies would not only enable a particular option, it would foreclose the others. Technologies essential to enable human exploration of Mars cannot prepare interchangeably for alternative futures; they would not allow us to choose later to Settle the Moon, unleash robust growth of Space Passenger Travel industries, or help the transition to a post-petroleum future with Space Solar Power for Earth. The paper concludes that a decades-long decision in the U.S.--whether made consciously or by default--to focus technology investment toward achieving human exploration of Mars someday would effectively preclude the alternative goals in our lifetime.

  11. Automated entry technologies for confined space work activities: A survey.

    Botti, Lucia; Ferrari, Emilio; Mora, Cristina

    2017-04-01

    Work in confined spaces poses a significant risk to workers and rescuers involved in the emergency response when an accident occurs. Despite several standards and regulations define the safety requirements for such activities, injuries, and fatalities still occur. Furthermore, the on-site inspections after accidents often reveal that both employers and employees fail to implement safe entry procedures. Removing the risk is possible by avoiding the worker entry, but many activities require the presence of the operator inside the confined space to perform manual tasks. The following study investigates the available technologies for hazardous confined space work activities, e.g., cleaning, inspecting, and maintenance tasks. The aim is to provide a systematic review of the automated solutions for high-risk activities in confined spaces, considering the non-man entry as the most effective confined space safety strategy. Second, this survey aims to provide suggestions for future research addressing the design of new technologies. The survey consists of about 60 papers concerning innovative technologies for confined space work activities. The document review shows that several solutions have been developed and automation can replace the workers for a limited number of hazardous tasks. Several activities still require the manual intervention due to the complex characteristics of confined spaces, e.g., to remove the remains of the automatic cleaning process from the bottom of a tank. The results show that available technologies require more flexibility to adapt to such occupational environments and further research is needed.

  12. Biosensors and preparation thereof

    2008-01-01

    A low-temp. prepn. method for a biosensor device with a layer of reagent on the sensor surface is disclosed. During manufg. biol. interaction between the biosensor substrate and the reagent layer material is reduced, e.g. by cooling the biosensor substrate and depositing the reagent layer on the

  13. Cholinesterase-based biosensors.

    Štěpánková, Šárka; Vorčáková, Katarína

    2016-01-01

    Recently, cholinesterase-based biosensors are widely used for assaying anticholinergic compounds. Primarily biosensors based on enzyme inhibition are useful analytical tools for fast screening of inhibitors, such as organophosphates and carbamates. The present review is aimed at compilation of the most important facts about cholinesterase based biosensors, types of physico-chemical transduction, immobilization strategies and practical applications.

  14. Space Internet Architectures and Technologies for NASA Enterprises

    Bhasin, Kul; Hayden, Jeffrey L.

    2001-01-01

    NASA's future communications services will be supplied through a space communications network that mirrors the terrestrial Internet in its capabilities and flexibility. The notional requirements for future data gathering and distribution by this Space Internet have been gathered from NASA's Earth Science Enterprise (ESE), the Human Exploration and Development in Space (HEDS), and the Space Science Enterprise (SSE). This paper describes a communications infrastructure for the Space Internet, the architectures within the infrastructure, and the elements that make up the architectures. The architectures meet the requirements of the enterprises beyond 2010 with Internet 'compatible technologies and functionality. The elements of an architecture include the backbone, access, inter-spacecraft and proximity communication parts. From the architectures, technologies have been identified which have the most impact and are critical for the implementation of the architectures.

  15. Translating University Biosensor Research to a High School Laboratory Experience

    Heldt, Caryn L.; Bank, Alex; Turpeinen, Dylan; King, Julia A.

    2016-01-01

    The need to increase science, technology, engineering, and mathematics (STEM) graduates is great. To interest more students into STEM degrees, we made our graphene biosensor research portable, inexpensive, and safe to demonstrate technology development to high school students. The students increased their knowledge of biosensors and proteins, and…

  16. Assessing Space Exploration Technology Requirements as a First Step Towards Ensuring Technology Readiness for International Cooperation in Space Exploration

    Laurini, Kathleen C.; Hufenbach, Bernhard; Satoh, Maoki; Piedboeuf, Jean-Claude; Neumann, Benjamin

    2010-01-01

    Advancing critical and enhancing technologies is considered essential to enabling sustainable and affordable human space exploration. Critical technologies are those that enable a certain class of mission, such as technologies necessary for safe landing on the Martian surface, advanced propulsion, and closed loop life support. Others enhance the mission by leading to a greater satisfaction of mission objectives or increased probability of mission success. Advanced technologies are needed to reduce mass and cost. Many space agencies have studied exploration mission architectures and scenarios with the resulting lists of critical and enhancing technologies being very similar. With this in mind, and with the recognition that human space exploration will only be enabled by agencies working together to address these challenges, interested agencies participating in the International Space Exploration Coordination Group (ISECG) have agreed to perform a technology assessment as an important step in exploring cooperation opportunities for future exploration mission scenarios. "The Global Exploration Strategy: The Framework for Coordination" was developed by fourteen space agencies and released in May 2007. Since the fall of 2008, several International Space Exploration Coordination Group (ISECG) participating space agencies have been studying concepts for human exploration of the moon. They have identified technologies considered critical and enhancing of sustainable space exploration. Technologies such as in-situ resource utilization, advanced power generation/energy storage systems, reliable dust resistant mobility systems, and closed loop life support systems are important examples. Similarly, agencies such as NASA, ESA, and Russia have studied Mars exploration missions and identified critical technologies. They recognize that human and robotic precursor missions to destinations such as LEO, moon, and near earth objects provide opportunities to demonstrate the

  17. A Strategy for Thailand's Space Technology Development: National Space Program (NSP)

    Pimnoo, Ammarin; Purivigraipong, Somphop

    2016-07-01

    The Royal Thai Government has established the National Space Policy Committee (NSPC) with mandates for setting policy and strategy. The NSPC is considering plans and budget allocation for Thai space development. NSPC's goal is to promote the utilization of space technology in a manner that is congruent with the current situation and useful for the economy, society, science, technology, educational development and national security. The first proposed initiative of the National Space Program (NSP) is co-development of THEOS-2, a next-generation satellite system that includes Thailand's second and third earth observation satellite (THAICHOTE-2 and THAICHOTE-3). THEOS-1 or THAICHOTE-1 was the first Earth Observation Satellite of Thailand launched in 2008. At present, the THAICHOTE-1 is over the lifetime, therefore the THEOS-2 project has been established. THEOS-2 is a complete Earth Observation System comprising THAICHOTE-2&3 as well as ground control segment and capacity building. Thus, NSPC has considered that Thailand should manage the space system. Geo-Informatics and Space Technology Development Agency (GISTDA) has been assigned to propose the initiative National Space Program (NSP). This paper describes the strategy of Thailand's National Space Program (NSP) which will be driven by GISTDA. First, NSP focuses on different aspects of the utilization of space on the basis of technology, innovation, knowledge and manpower. It contains driving mechanisms related to policy, implementation and use in order to promote further development. The Program aims to increase economic competitiveness, reduce social disparity, and improve social security, natural resource management and environmental sustainability. The NSP conceptual framework includes five aspects: communications satellites, earth observation satellite systems, space economy, space exploration and research, and NSP administration. THEOS-2 is considered a part of NSP with relevance to the earth observation

  18. Projecting technology change to improve space technology planning and systems management

    Walk, Steven Robert

    2011-04-01

    Projecting technology performance evolution has been improving over the years. Reliable quantitative forecasting methods have been developed that project the growth, diffusion, and performance of technology in time, including projecting technology substitutions, saturation levels, and performance improvements. These forecasts can be applied at the early stages of space technology planning to better predict available future technology performance, assure the successful selection of technology, and improve technology systems management strategy. Often what is published as a technology forecast is simply scenario planning, usually made by extrapolating current trends into the future, with perhaps some subjective insight added. Typically, the accuracy of such predictions falls rapidly with distance in time. Quantitative technology forecasting (QTF), on the other hand, includes the study of historic data to identify one of or a combination of several recognized universal technology diffusion or substitution patterns. In the same manner that quantitative models of physical phenomena provide excellent predictions of system behavior, so do QTF models provide reliable technological performance trajectories. In practice, a quantitative technology forecast is completed to ascertain with confidence when the projected performance of a technology or system of technologies will occur. Such projections provide reliable time-referenced information when considering cost and performance trade-offs in maintaining, replacing, or migrating a technology, component, or system. This paper introduces various quantitative technology forecasting techniques and illustrates their practical application in space technology and technology systems management.

  19. Innovative Technologies for Efficient Pharmacotherapeutic Management in Space

    Putcha, Lakshmi; Daniels, Vernie

    2014-01-01

    Current and future Space exploration missions and extended human presence in space aboard the ISS will expose crew to risks that differ both quantitatively and qualitatively from those encountered before by space travelers and will impose an unknown risk of safety and crew health. The technology development challenges for optimizing therapeutics in space must include the development of pharmaceuticals with extended stability, optimal efficacy and bioavailability with minimal toxicity and side effects. Innovative technology development goals may include sustained/chronic delivery preventive health care products and vaccines, low-cost high-efficiency noninvasive, non-oral dosage forms with radio-protective formulation matrices and dispensing technologies coupled with self-reliant tracking technologies for quality assurance and quality control assessment. These revolutionary advances in pharmaceutical technology will assure human presence in space and healthy living on Earth. Additionally, the Joint Commission on Accreditation of Healthcare Organizations advocates the use of health information technologies to effectively execute all aspects of medication management (prescribing, dispensing, and administration). The advent of personalized medicine and highly streamlined treatment regimens stimulated interest in new technologies for medication management. Intelligent monitoring devices enhance medication accountability compliance, enable effective drug use, and offer appropriate storage and security conditions for dangerous drug and controlled substance medications in remote sites where traditional pharmacies are unavailable. These features are ideal for Exploration Medical Capabilities. This presentation will highlight current novel commercial off-the-shelf (COTS) intelligent medication management devices for the unique dispensing, therapeutic drug monitoring, medication tracking, and drug delivery demands of exploration space medical operations.

  20. An overview of DARPA's advanced space technology program

    Nicastri, E.; Dodd, J.

    1993-02-01

    The Defense Advanced Research Projects Agency (DARPA) is the central research and development organization of the DoD and, as such, has the primary responsibility for the maintenance of U.S. technological superiority over potential adversaries. DARPA's programs focus on technology development and proof-of-concept demonstrations of both evolutionary and revolutionary approaches for improved strategic, conventional, rapid deployment and sea power forces, and on the scientific investigation into advanced basic technologies of the future. DARPA can move quickly to exploit new ideas and concepts by working directly with industry and universities. For four years, DARPA's Advanced Space Technology Program (ASTP) has addressed various ways to improve the performance of small satellites and launch vehicles. The advanced technologies that are being and will be developed by DARPA for small satellites can be used just as easily on large satellites. The primary objective of the ASTP is to enhance support to operational commanders by developing and applying advanced technologies that will provide cost-effective, timely, flexible, and responsive space systems. Fundamental to the ASTP effort is finding new ways to do business with the goal of quickly inserting new technologies into DoD space systems while reducing cost. In our view, these methods are prime examples of what may be termed 'technology leveraging.' The ASTP has initiated over 50 technology projects, many of which were completed and transitioned to users. The objectives are to quickly qualify these higher risk technologies for use on future programs and reduce the risk of inserting these technologies into major systems, and to provide the miniaturized systems that would enable smaller satellites to have significant - rather than limited - capability. Only a few of the advanced technologies are described, the majority of which are applicable to both large and small satellites.

  1. Free-piston Stirling technology for space power

    Slaby, Jack G.

    1989-01-01

    An overview is presented of the NASA Lewis Research Center free-piston Stirling engine activities directed toward space power. This work is being carried out under NASA's new Civil Space Technology Initiative (CSTI). The overall goal of CSTI's High Capacity Power element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA space missions. The Stirling cycle offers an attractive power conversion concept for space power needs. Discussed here is the completion of the Space Power Demonstrator Engine (SPDE) testing-culminating in the generation of 25 kW of engine power from a dynamically-balanced opposed-piston Stirling engine at a temperature ratio of 2.0. Engine efficiency was approximately 22 percent. The SPDE recently has been divided into two separate single-cylinder engines, called Space Power Research Engine (SPRE), that now serve as test beds for the evaluation of key technology disciplines. These disciplines include hydrodynamic gas bearings, high-efficiency linear alternators, space qualified heat pipe heat exchangers, oscillating flow code validation, and engine loss understanding.

  2. Space matters: the relational power of mobile technologies

    Nancy Odendaal

    2014-01-01

    Full Text Available The ubiquitous presence of mobile telephony and proliferation of digital networks imply a critical role for these technologies in overcoming the constraints of space in fragmented cities. Academic literature draws from a range of disciplines but fails to address the significance of new technologies for African and South African cities. Debates on technologies and urban spaces reflect a Northern bias and case literature that dwells on the developmental aspects of ICT do not engage with the broader significance with regards to urban change in African cities. This research addresses these gaps by examining the local transformative qualities of mobile telephony in a South African city, Durban. It focuses on the ways in which informal traders active in the city use technology. Actor-network theory was used in the analysis of the field work, uncovering material and human actors, network stabilization processes and agency in determining the transformative potential of this form of digital networking at city and local scales. Findings indicate that appropriation of technology is informed by livelihood strategies. Innovation is enabled when translation extends to appropriation. More in-depth research is needed on how technology is molded and appropriated to suit livelihoods. Throughout the research the spatial dimensions of the relationship between mobile telephony and networks were considered. The network spaces that emerge from actor relations do not correspond with the physical spaces usually considered in policy.

  3. Synthetic biology for microbial heavy metal biosensors.

    Kim, Hyun Ju; Jeong, Haeyoung; Lee, Sang Jun

    2018-02-01

    Using recombinant DNA technology, various whole-cell biosensors have been developed for detection of environmental pollutants, including heavy metal ions. Whole-cell biosensors have several advantages: easy and inexpensive cultivation, multiple assays, and no requirement of any special techniques for analysis. In the era of synthetic biology, cutting-edge DNA sequencing and gene synthesis technologies have accelerated the development of cell-based biosensors. Here, we summarize current technological advances in whole-cell heavy metal biosensors, including the synthetic biological components (bioparts), sensing and reporter modules, genetic circuits, and chassis cells. We discuss several opportunities for improvement of synthetic cell-based biosensors. First, new functional modules must be discovered in genome databases, and this knowledge must be used to upgrade specific bioparts through molecular engineering. Second, modules must be assembled into functional biosystems in chassis cells. Third, heterogeneity of individual cells in the microbial population must be eliminated. In the perspectives, the development of whole-cell biosensors is also discussed in the aspects of cultivation methods and synthetic cells.

  4. Biosensors based on cantilevers.

    Alvarez, Mar; Carrascosa, Laura G; Zinoviev, Kiril; Plaza, Jose A; Lechuga, Laura M

    2009-01-01

    Microcantilevers based-biosensors are a new label-free technique that allows the direct detection of biomolecular interactions in a label-less way and with great accuracy by translating the biointeraction into a nanomechanical motion. Low cost and reliable standard silicon technologies are widely used for the fabrication of cantilevers with well-controlled mechanical properties. Over the last years, the number of applications of these sensors has shown a fast growth in diverse fields, such as genomic or proteomic, because of the biosensor flexibility, the low sample consumption, and the non-pretreated samples required. In this chapter, we report a dedicated design and a fabrication process of highly sensitive microcantilever silicon sensors. We will describe as well an application of the device in the environmental field showing the immunodetection of an organic toxic pesticide as an example. The cantilever biofunctionalization process and the subsequent pesticide determination are detected in real time by monitoring the nanometer-scale bending of the microcantilever due to a differential surface stress generated between both surfaces of the device.

  5. In Vitro Evaluation of Fluorescence Glucose Biosensor Response

    Aloraefy, Mamdouh; Pfefer, T. Joshua; Ramella-Roman, Jessica C.; Sapsford, Kim E.

    2014-01-01

    Rapid, accurate, and minimally-invasive glucose biosensors based on Förster Resonance Energy Transfer (FRET) for glucose measurement have the potential to enhance diabetes control. However, a standard set of in vitro approaches for evaluating optical glucose biosensor response under controlled conditions would facilitate technological innovation and clinical translation. Towards this end, we have identified key characteristics and response test methods, fabricated FRET-based glucose biosensor...

  6. Development priorities for in-space propulsion technologies

    Johnson, Les; Meyer, Michael; Palaszewski, Bryan; Coote, David; Goebel, Dan; White, Harold

    2013-02-01

    During the summer of 2010, NASA's Office of Chief Technologist assembled 15 civil service teams to support the creation of a NASA integrated technology roadmap. The Aero-Space Technology Area Roadmap is an integrated set of technology area roadmaps recommending the overall technology investment strategy and prioritization for NASA's technology programs. The integrated set of roadmaps will provide technology paths needed to meet NASA's strategic goals. The roadmaps have been reviewed by senior NASA management and the National Research Council. With the exception of electric propulsion systems used for commercial communications satellite station-keeping and a handful of deep space science missions, almost all of the rocket engines in use today are chemical rockets; that is, they obtain the energy needed to generate thrust by combining reactive chemicals to create a hot gas that is expanded to produce thrust. A significant limitation of chemical propulsion is that it has a relatively low specific impulse. Numerous concepts for advanced propulsion technologies with significantly higher values of specific impulse have been developed over the past 50 years. Advanced in-space propulsion technologies will enable much more effective exploration of our solar system, near and far, and will permit mission designers to plan missions to "fly anytime, anywhere, and complete a host of science objectives at the destinations" with greater reliability and safety. With a wide range of possible missions and candidate propulsion technologies with very diverse characteristics, the question of which technologies are 'best' for future missions is a difficult one. A portfolio of technologies to allow optimum propulsion solutions for a diverse set of missions and destinations are described in the roadmap and herein.

  7. Evaluating Russian space nuclear reactor technology for United States applications

    Polansky, G.F.; Schmidt, G.L.; Voss, S.S.; Reynolds, E.L.

    1994-01-01

    Space nuclear power and nuclear electric propulsion are considered important technologies for planetary exploration, as well as selected earth orbit applications. The Nuclear Electric Propulsion Space Test Program (NEPSTP) was intended to provide an early flight demonstration of these technologies at relatively low cost through extensive use of existing Russian technology. The key element of Russian technology employed in the program was the Topaz II reactor. Refocusing of the activities of the Ballistic Missile Defense Organization (BMDO), combined with budgetary pressures, forced the cancellation of the NEPSTP at the end of the 1993 fiscal year. The NEPSTP was faced with many unique flight qualification issues. In general, the launch of a spacecraft employing a nuclear reactor power system complicates many spacecraft qualification activities. However, the NEPSTP activities were further complicated because the reactor power system was a Russian design. Therefore, this program considered not only the unique flight qualification issues associated with space nuclear power, but also with differences between Russian and United States flight qualification procedures. This paper presents an overview of the NEPSTP. The program goals, the proposed mission, the spacecraft, and the Topaz II space nuclear power system are described. The subject of flight qualification is examined and the inherent difficulties of qualifying a space reactor are described. The differences between United States and Russian flight qualification procedures are explored. A plan is then described that was developed to determine an appropriate flight qualification program for the Topaz II reactor to support a possible NEPSTP launch

  8. Future of dual-use space awareness technologies

    Kislitsyn, Boris V.; Idell, Paul S.; Crawford, Linda L.

    2000-10-01

    The use of all classes of space systems, whether owned by defense, civil, commercial, scientific, allied or foreign organizations, is increasing rapidly. In turn, the surveillance of such systems and activities in space are of interest to all parties. Interests will only increase in time and with the new ways to exploit the space environment. However, the current space awareness infrastructure and capabilities are not maintaining pace with the demands and advanced technologies being brought online. The use of surveillance technologies, some of which will be discussed in the conference, will provide us the eventual capability to observe and assess the environment, satellite health and status, and the uses of assets on orbit. This provides us a space awareness that is critical to the military operator and to the commercial entrepreneur for their respective successes. Thus the term 'dual-use technologies' has become a reality. For this reason we will briefly examine the background, current, and future technology trends that can lead us to some insights for future products and services.

  9. Transformational Technologies to Expedite Space Access and Development

    Rather, John D. G.

    2010-01-01

    Throughout history the emergence of new technologies has enabled unforeseen breakthrough capabilities that rapidly transformed the world. Some global examples from the twentieth century include AC electric power, nuclear energy, and turbojet engines. At the systems level, success of both Apollo and the Space Shuttle programs depended upon taming hydrogen propulsion and developing high-temperature atmospheric reentry materials. Human space development now is stymied because of a great need for breakthrough technologies and strategies. It is believed that new capabilities exist within the present states-of-the-art of superconducting technology that can be implemented to transform the future of human space development. This paper is an overview of three other papers presented within this forum, which summarizes the principles and consequences of StarTram, showing how the resulting breakthrough advantages can lead directly to safe space tourism and massive development of the moon, Mars and the outer solar system. StarTram can implement cost-effective solar power from space, simple utilization of asteroid material to protect humans from ionizing radiation, and effective defense of the Earth from devastating cosmic impacts. Synergistically, StarTram technologies will revolutionize ground transportation on the Earth, leading to enormous reduction in energy consumption and creation of millions of jobs. High energy lasers will also be discussed because of their importance to power beaming applications.

  10. Free-piston Stirling technology for space power

    Slaby, J.G.

    1994-01-01

    An overview is presented of the NASA Lewis Research Center free-piston Stirling engine activities directed toward space power. This work is being carried out under NASA's new Civil Space Technology Initiative (CSTI). The overall goal of CSTI's High Capacity Power element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA space missions. The Stirling cycle offers an attractive power conversion concept for space power needs. Discussed in this paper is the completion of the Space Power Demonstrator Engine (SPDE) testing - culminating in the generation of 25 kW of engine power from a dynamically-balanced opposed-piston Stirling engine at a temperature ratio of 2.0. Engine efficiency was approximately 22 percent. The SPDE recently has been divided into two separate single-cylinder engines, called Space Power Research Engines (SPRE), that now serve as test beds for the evaluation of key technology disciplines. These disciplines include hydrodynamic gas bearings, high-efficiency linear alternators, space qualified heat pipe heat exchangers, oscillating flow code validation, and engine loss understanding. The success of the SPDE at 650 K has resulted in a more ambitious Stirling endeavor - the design, fabrication, test and evaluation of a designed-for-space 25 kW per cylinder Stirling Space Engine (SSE). The SSE will operate at a hot metal temperature of 1050 K using superalloy materials. This design is a low temperature confirmation of the 1300 K design. It is the 1300 K free-piston Stirling power conversion system that is the ultimate goal; to be used in conjunction with the SP-100 reactor. The approach to this goal is in three temperature steps. However, this paper concentrates on the first two phases of this program - the 650 K SPDE and the 1050 K SSE

  11. Ubiquitous Emergency Medical Service System Based on Wireless Biosensors, Traffic Information, and Wireless Communication Technologies: Development and Evaluation

    Tan-Hsu Tan

    2017-01-01

    Full Text Available This study presents a new ubiquitous emergency medical service system (UEMS that consists of a ubiquitous tele-diagnosis interface and a traffic guiding subsystem. The UEMS addresses unresolved issues of emergency medical services by managing the sensor wires for eliminating inconvenience for both patients and paramedics in an ambulance, providing ubiquitous accessibility of patients’ biosignals in remote areas where the ambulance cannot arrive directly, and offering availability of real-time traffic information which can make the ambulance reach the destination within the shortest time. In the proposed system, patient’s biosignals and real-time video, acquired by wireless biosensors and a webcam, can be simultaneously transmitted to an emergency room for pre-hospital treatment via WiMax/3.5 G networks. Performances of WiMax and 3.5 G, in terms of initialization time, data rate, and average end-to-end delay are evaluated and compared. A driver can choose the route of the shortest time among the suggested routes by Google Maps after inspecting the current traffic conditions based on real-time CCTV camera streams and traffic information. The destination address can be inputted vocally for easiness and safety in driving. A series of field test results validates the feasibility of the proposed system for application in real-life scenarios.

  12. 2004 Space Report: Environment and Strategy for Space Research at NATO's Research and Technology Organisation (RTO)

    Woods-Vedeler, Jessica A.

    2007-01-01

    This report describes the motivation for and a strategy to enhance the NATO Research and Technology Organisation's (RTO) current space research effort to reflect NATO's growing military dependence on space systems. Such systems and services provided by these systems are critical elements of military operations. NATO uses space systems for operational planning and support, communication, radio navigation, multi-sensor and multi-domain demonstrations. Such systems are also used to promote regional stability. A quantitative analysis of work related to space in the NATO RTO showed that during the period of 1998 - 2004, 5% of the research pursued in the NATO RTO has been clearly focused on space applications. Challenging environmental and organizational barriers for increasing RTO space research were identified. In part, these include lack of sufficient space expertise representation on panels, the military sensitivity of space, current panel work loads and the need for specific technical recommendations from peers. A strategy for enhancing space research in the RTO is to create a limited-life Space Advisory Group (SAG) composed of Space Expert Consultants who are panel members with appropriate expertise and additional expertise from the nations. The SAG will recommend and find support in the nations for specific technical activities related to space in the areas of Space Science, Remote Sensing Data Analysis, Spacecraft Systems, Surveillance and Early Warning, Training and Simulation and Policy. An RTO Space Advisory Group will provide an organizational mechanism to gain recognition of RTO as a forum for trans-Atlantic defence space research and to enhance space research activities.

  13. Biosensors-on-chip: a topical review

    Chen, Sensen; Shamsi, Mohtashim H

    2017-01-01

    This review will examine the integration of two fields that are currently at the forefront of science, i.e. biosensors and microfluidics. As a lab-on-a-chip (LOC) technology, microfluidics has been enriched by the integration of various detection tools for analyte detection and quantitation. The application of such microfluidic platforms is greatly increased in the area of biosensors geared towards point-of-care diagnostics. Together, the merger of microfluidics and biosensors has generated miniaturized devices for sample processing and sensitive detection with quantitation. We believe that microfluidic biosensors (biosensors-on-chip) are essential for developing robust and cost effective point-of-care diagnostics. This review is relevant to a variety of disciplines, such as medical science, clinical diagnostics, LOC technologies including MEMs/NEMs, and analytical science. Specifically, this review will appeal to scientists working in the two overlapping fields of biosensors and microfluidics, and will also help new scientists to find their directions in developing point-of-care devices. (topical review)

  14. Biosensors for DNA sequence detection

    Vercoutere, Wenonah; Akeson, Mark

    2002-01-01

    DNA biosensors are being developed as alternatives to conventional DNA microarrays. These devices couple signal transduction directly to sequence recognition. Some of the most sensitive and functional technologies use fibre optics or electrochemical sensors in combination with DNA hybridization. In a shift from sequence recognition by hybridization, two emerging single-molecule techniques read sequence composition using zero-mode waveguides or electrical impedance in nanoscale pores.

  15. The field effect transistor DNA biosensor based on ITO nanowires in label-free hepatitis B virus detecting compatible with CMOS technology.

    Shariati, Mohsen

    2018-05-15

    In this paper the field-effect transistor DNA biosensor for detecting hepatitis B virus (HBV) based on indium tin oxide nanowires (ITO NWs) in label free approach has been fabricated. Because of ITO nanowires intensive conductance and functional modified surface, the probe immobilization and target hybridization were increased strongly. The high resolution transmission electron microscopy (HRTEM) measurement showed that ITO nanowires were crystalline and less than 50nm in diameter. The single-stranded hepatitis B virus DNA (SS-DNA) was immobilized as probe on the Au-modified nanowires. The DNA targets were measured in a linear concentration range from 1fM to 10µM. The detection limit of the DNA biosensor was about 1fM. The time of the hybridization process for defined single strand was 90min. The switching ratio of the biosensor between "on" and "off" state was ~ 1.1 × 10 5 . For sensing the specificity of the biosensor, non-complementary, mismatch and complementary DNA oligonucleotide sequences were clearly discriminated. The HBV biosensor confirmed the highly satisfied specificity for differentiating complementary sequences from non-complementary and the mismatch oligonucleotides. The response time of the DNA sensor was 37s with a high reproducibility. The stability and repeatability of the DNA biosensor showed that the peak current of the biosensor retained 98% and 96% of its initial response for measurements after three and five weeks, respectively. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Space-reactor electric systems: subsystem technology assessment

    Anderson, R.V.; Bost, D.; Determan, W.R.

    1983-01-01

    This report documents the subsystem technology assessment. For the purpose of this report, five subsystems were defined for a space reactor electric system, and the report is organized around these subsystems: reactor; shielding; primary heat transport; power conversion and processing; and heat rejection. The purpose of the assessment was to determine the current technology status and the technology potentials for different types of the five subsystems. The cost and schedule needed to develop these potentials were estimated, and sets of development-compatible subsystems were identified

  17. Plant cell technologies in space: Background, strategies and prospects

    Kirkorian, A. D.; Scheld, H. W.

    1987-01-01

    An attempt is made to summarize work in plant cell technologies in space. The evolution of concepts and the general principles of plant tissue culture are discussed. The potential for production of high value secondary products by plant cells and differentiated tissue in automated, precisely controlled bioreactors is discussed. The general course of the development of the literature on plant tissue culture is highlighted.

  18. Military space power systems technology trends and issues

    Barthelemy, R.R.; Massie, L.D.

    1985-01-01

    This paper assesses baseload and above-baseload (alert, active, pulsed and burst mode) power system options, places them in logical perspective relative to power level and operating time, discusses power systems technology state-of-the-art and trends and finally attempts to project future (post 2000) space power system capabilities

  19. A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

    2015-07-21

    Hybrid Biosensor Jieun Lee1,2, Jaeman Jang1, Bongsik Choi1, Jinsu Yoon1, Jee-Yeon Kim3, Yang-Kyu Choi3, Dong Myong Kim1, Dae Hwan Kim1 & Sung-Jin Choi1...This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response...of field-effect-transistor (FET)-based biosensors . The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential

  20. Impedimetric biosensors for medical applications current progress and challenges

    Rushworth, Jo V; Goode, Jack A; Pike, Douglas J; Ahmed, Asif; Millner, Paul

    2014-01-01

    In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer-by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalization and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph ...

  1. Refractory alloy technology for space nuclear power applications

    Cooper, R.H. Jr.; Hoffman, E.E.

    1984-01-01

    Purpose of this symposium is twofold: (1) to review and document the status of refractory alloy technology for structural and fuel-cladding applications in space nuclear power systems, and (2) to identify and document the refractory alloy research and development needs for the SP-100 Program in both the short and the long term. In this symposium, an effort was made to recapture the space reactor refractory alloy technology that was cut off in midstream around 1973 when the national space nuclear reactor program began in the early 1960s, was terminated. The six technical areas covered in the program are compatibility, processing and production, welding and component fabrication, mechanical and physical properties, effects of irradiation, and machinability. The refractory alloys considered are niobium, molybdenum, tantalum, and tungsten. Thirteen of the 14 pages have been abstracted separately. The remaining paper summarizes key needs for further R and D on refractory alloys

  2. Refractory alloy technology for space nuclear power applications

    Cooper, R.H. Jr.; Hoffman, E.E. (eds.)

    1984-01-01

    Purpose of this symposium is twofold: (1) to review and document the status of refractory alloy technology for structural and fuel-cladding applications in space nuclear power systems, and (2) to identify and document the refractory alloy research and development needs for the SP-100 Program in both the short and the long term. In this symposium, an effort was made to recapture the space reactor refractory alloy technology that was cut off in midstream around 1973 when the national space nuclear reactor program began in the early 1960s, was terminated. The six technical areas covered in the program are compatibility, processing and production, welding and component fabrication, mechanical and physical properties, effects of irradiation, and machinability. The refractory alloys considered are niobium, molybdenum, tantalum, and tungsten. Thirteen of the 14 pages have been abstracted separately. The remaining paper summarizes key needs for further R and D on refractory alloys. (DLC)

  3. Technology demonstration of space intravehicular automation and robotics

    Morris, A. Terry; Barker, L. Keith

    1994-01-01

    Automation and robotic technologies are being developed and capabilities demonstrated which would increase the productivity of microgravity science and materials processing in the space station laboratory module, especially when the crew is not present. The Automation Technology Branch at NASA Langley has been working in the area of intravehicular automation and robotics (IVAR) to provide a user-friendly development facility, to determine customer requirements for automated laboratory systems, and to improve the quality and efficiency of commercial production and scientific experimentation in space. This paper will describe the IVAR facility and present the results of a demonstration using a simulated protein crystal growth experiment inside a full-scale mockup of the space station laboratory module using a unique seven-degree-of-freedom robot.

  4. Space Resource Utilization: Technologies and Potential Synergism with Terrestrial Mining

    Sanders, Gerald B.

    2015-01-01

    Space Resources and Their Uses: The idea of using resources in space to support human exploration and settlement or for economic development and profit beyond the surface of Earth has been proposed and discussed for decades. Work on developing a method to extract oxygen from lunar regolith started even before humans set foot on the Moon for the first time. The use of space resources, commonly referred to as In Situ Resource Utilization (ISRU), involves the processes and operations to harness and utilize resources in space (both natural and discarded) to create products for subsequent use. Potential space resources include water, solar wind implanted volatiles (hydrogen, helium, carbon, nitrogen, etc.), vast quantities of metals and minerals in extraterrestrial soils, atmospheric constituents, unlimited solar energy, regions of permanent light and darkness, the vacuum and zero-gravity of space itself, trash and waste from human crew activities, and discarded hardware that has completed its primary purpose. ISRU covers a wide variety of concepts, technical disciplines, technologies, and processes. When considering all aspects of ISRU, there are 5 main areas that are relevant to human space exploration and the commercialization of space: 1. Resource Characterization and Mapping, 2. In Situ Consumables Production, 3. Civil Engineering and Construction, 4. In Situ Energy Production and Storage, and 5. In Situ Manufacturing.

  5. Lidar technologies for airborne and space-based applications

    Henson, T.D.; Schmitt, R.L.; Sobering, T.J.; Raymond, T.D.; Stephenson, D.A.

    1994-10-01

    This study identifies technologies required to extend the capabilities of airborne light detection and ranging (lidar) systems and establish the feasibility of autonomous space-based lidars. Work focused on technologies that enable the development of a lightweight, low power, rugged and autonomous Differential Absorption Lidar (DIAL) instruments. Applications for airborne or space-based DIAL include the measurement of water vapor profiles in support of climate research and processing-plant emissions signatures for environmental and nonproliferation monitoring. A computer-based lidar performance model was developed to allow trade studies to be performed on various technologies and system configurations. It combines input from the physics (absorption line strengths and locations) of the problem, the system requirements (weight, power, volume, accuracy), and the critical technologies available (detectors, lasers, filters) to produce the best conceptual design. Conceptual designs for an airborne and space-based water vapor DIAL, and a detailed design of a ground-based water vapor DIAL demonstration system were completed. Future work planned includes the final testing, integration, and operation of the demonstration system to prove the capability of the critical enabling technologies identified

  6. Composites Materials and Manufacturing Technologies for Space Applications

    Vickers, J. H.; Tate, L. C.; Gaddis, S. W.; Neal, R. E.

    2016-01-01

    Composite materials offer significant advantages in space applications. Weight reduction is imperative for deep space systems. However, the pathway to deployment of composites alternatives is problematic. Improvements in the materials and processes are needed, and extensive testing is required to validate the performance, qualify the materials and processes, and certify components. Addressing these challenges could lead to the confident adoption of composites in space applications and provide spin-off technical capabilities for the aerospace and other industries. To address the issues associated with composites applications in space systems, NASA sponsored a Technical Interchange Meeting (TIM) entitled, "Composites Materials and Manufacturing Technologies for Space Applications," the proceedings of which are summarized in this Conference Publication. The NASA Space Technology Mission Directorate and the Game Changing Program chartered the meeting. The meeting was hosted by the National Center for Advanced Manufacturing (NCAM)-a public/private partnership between NASA, the State of Louisiana, Louisiana State University, industry, and academia, in association with the American Composites Manufacturers Association. The Louisiana Center for Manufacturing Sciences served as the coordinator for the TIM.

  7. From microsystems technology to the Saenger II space transportation system

    Vogels, Hanns Arnt

    The role of space projects as drivers and catalysts of technology advances is discussed and illustrated from the perspective of the West German aerospace industry, summarizing a talk presented at the 1986 meeting of the German aerospace society DGLR. The history of space-transportation-system (STS) technology since the 1950s is traced, emphasizing the needs for greater payload weights and lower costs, and the design concept of Saenger II, a proposed two-stage ESA STS employing a hypersonic jet transport aircraft as its first stage, is outlined. It is argued that experience gained in developing the rocket-launched Hermes STS will be applicable to the second stage of Saenger II. Recent developments in microsystems (combining microelectronics, micromechanics, and microoptics), advanced materials (fiber-reinforced plastics, metals, and ceramics), and energy technology (hydrogen-based systems and solar cells) are surveyed, and their applicability to STSs is considered.

  8. Critical Technology Determination for Future Human Space Flight

    Mercer, Carolyn R.; Vangen, Scott D.; Williams-Byrd, Julie A.; Stecklein, Jonette M.; Rahman, Shamim A.; Rosenthal, Matthew E.; Hornyak, David M.; Alexander, Leslie; Korsmeyer, David J.; Tu, Eugene L.; hide

    2012-01-01

    As the National Aeronautics and Space Administration (NASA) prepares to extend human presence throughout the solar system, technical capabilities must be developed to enable long duration flights to destinations such as near Earth asteroids, Mars, and extended stays on the Moon. As part of the NASA Human Spaceflight Architecture Team, a Technology Development Assessment Team has identified a suite of critical technologies needed to support this broad range of missions. Dialog between mission planners, vehicle developers, and technologists was used to identify a minimum but sufficient set of technologies, noting that needs are created by specific mission architecture requirements, yet specific designs are enabled by technologies. Further consideration was given to the re-use of underlying technologies to cover multiple missions to effectively use scarce resources. This suite of critical technologies is expected to provide the needed base capability to enable a variety of possible destinations and missions. This paper describes the methodology used to provide an architecture-driven technology development assessment ("technology pull"), including technology advancement needs identified by trade studies encompassing a spectrum of flight elements and destination design reference missions.

  9. In-Space Propulsion Technologies for Robotic Exploration of the Solar System

    Johnson, Les; Meyer, Rae Ann; Frame, Kyle

    2006-01-01

    Supporting NASA's Science Mission Directorate, the In-Space Propulsion Technology Program is developing the next generation of space propulsion technologies for robotic, deep-space exploration. Recent technological advancements and demonstrations of key, high-payoff propulsion technologies have been achieved and will be described. Technologies under development and test include aerocapture, solar electric propulsion, solar sail propulsion, and advanced chemical propulsion.

  10. Biosensors and bioelectronics

    Karunakaran, Chandran; Benjamin, Robson

    2015-01-01

    Biosensors and Bioelectronics presents the rapidly evolving methodologies that are relevant to biosensors and bioelectronics fabrication and characterization. The book provides a comprehensive understanding of biosensor functionality, and is an interdisciplinary reference that includes a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers. Authored by a team of bioinstrumentation experts, this book serves as a blueprint for performing advanced fabrication and characterization of sensor systems-arming readers with an application-based re

  11. Theoretical analysis and simulation study of low-power CMOS electrochemical impedance spectroscopy biosensor in 55 nm deeply depleted channel technology for cell-state monitoring

    Itakura, Keisuke; Kayano, Keisuke; Nakazato, Kazuo; Niitsu, Kiichi

    2018-01-01

    We present an impedance-detection complementary metal oxide semiconductor (CMOS) biosensor circuit for cell-state observation. The proposed biosensor can measure the expected impedance values encountered by a cell-state observation measurement system within a 0.1-200 MHz frequency range. The proposed device is capable of monitoring the intracellular conditions necessary for real-time cell-state observation, and can be fabricated using a 55 nm deeply depleted channel CMOS process. Operation of the biosensor circuit with 0.9 and 1.7 V supply voltages is verified via a simulated program with integrated circuit emphasis (SPICE) simulation. The power consumption is 300 µW. Further, the standby power consumption is 290 µW, indicating that this biosensor is a low-power instrument suitable for use in Internet of Things (IoT) devices.

  12. The technology management process at the European space agency

    Guglielmi, M.; Williams, E.; Groepper, P.; Lascar, S.

    2010-03-01

    Technology is developed at the European Space Agency (ESA) under several programmes: corporate and domain specific, mandatory and optional, with different time horizons and covering different levels of the TRL scale. To improve the transparency and efficiency of the complete process, it was felt necessary to establish an agreed end to end process for the management of all technology R&D activity that could: Include all ESA programmes and consider the requirements of European users Lead to coordinated multi-year work plan and yearly procurement plans Prepare and enable future European space programmes Be harmonized with national initiatives in Europe Thereby establishing the basis for a product policy to reduce risks to technology users, reduce costs and delays, and enhance industrial competitiveness and non-dependence. In response to the above needs, ESA has developed a technology management process called the ESA End-to-End process (E2E), from establishment of the strategy to the monitoring and evaluation of R&D results. In this paper, the complete process will be described in detail including a discussion on its strengths and limitations, and its links to the wider European Harmonization process. The paper will be concluded with the introduction of the ESA Technology Tree: a basic tool to structure and facilitate communication about technology issues.

  13. Definition of technology development missions for early space stations: Large space structures

    Gates, R. M.; Reid, G.

    1984-01-01

    The objectives studied are the definition of the tested role of an early Space Station for the construction of large space structures. This is accomplished by defining the LSS technology development missions (TDMs) identified in phase 1. Design and operations trade studies are used to identify the best structural concepts and procedures for each TDMs. Details of the TDM designs are then developed along with their operational requirements. Space Station resources required for each mission, both human and physical, are identified. The costs and development schedules for the TDMs provide an indication of the programs needed to develop these missions.

  14. Linking the space shuttle and space stations early docking technologies from concept to implementation

    Shayler, David J

    2017-01-01

    How could the newly authorized space shuttle help in the U.S. quest to build a large research station in Earth orbit? As a means of transporting goods, the shuttle could help supply the parts to the station. But how would the two entitles be physically linked? Docking technologies had to constantly evolve as the designs of the early space stations changed. It was hoped the shuttle would make missions to the Russian Salyut and American Skylab stations, but these were postponed until the Mir station became available, while plans for getting a new U. S. space station underway were stalled. In Linking the Space Shuttle and Space Stations, the author delves into the rich history of the Space Shuttle and its connection to these early space stations, culminating in the nine missions to dock the shuttle to Mir. By 1998, after nearly three decades of planning and operations, shuttle missions to Mir had resulted in: • A proven system to link up the space shuttle to a space station • Equipment and hands-on experienc...

  15. Optimize Use of Space Research and Technology for Medical Devices

    Minnifield, Nona K.

    2012-01-01

    systems, and cutting-edge component technologies to conduct a wide range of scientific observations and measurements. These technologies are also considered for practical applications that benefit society in remarkable ways. At NASA Goddard, the technology transfer initiative promotes matching technologies from Earth and space science needs to targeted industry sectors. This requires clear knowledge of industry needs and priorities and social demands. The process entails matching mature technologies where there are known innovation challenges and good opportunities for matching technology needs. This requires creative thinking and takes commitment of time and resources. Additionally, we also look at applications for known hot industry or societal needs. Doing so has given us occasion to host discussions with representatives from industry, academia, government organizations, and societal special interest groups about the application of NASA Goddard technologies for devices used in medical monitoring and detection tools. As a result, partnerships have been established. Innovation transpired when new products were enabled because of NASA Goddard research and technology programs.

  16. A Review of Tribomaterial Technology for Space Nuclear Power Systems

    Stanford, Malcolm K.

    2007-01-01

    The National Aeronautics and Space Administration (NASA) has recently proposed a nuclear closed-cycle electric power conversion system for generation of 100-kW of electrical power for space exploration missions. A critical issue is the tribological performance of sliding components within the power conversion unit that will be exposed to neutron radiation. This paper presents a review of the main considerations that have been made in the selection of solid lubricants for similar applications in the past as well as a recommendations for continuing development of the technology.

  17. The Social Shaping of Technology: A New Space for Politics?

    Yoshinaka, Yutaka; Clausen, Christian; Hansen, Anne Grethe

    2003-01-01

    change. We identify a new perspective on political processes, with a broader focus on the political dimensions of technological decision-making, and a broader treatment of socio-technical space, maintaining a focus on inclusion and exclusion of actors, salient issues and how they are dealt...... effects, which are non-neutral and distributed, as the processes of shaping themselves have been. The chapter develops the notion of SST through socio-technical spaces. Here a heterogeneous set of elements, comprising of techniques, social actors, attribution of meanings, and problem definitions, etc...

  18. Laser transmitter for Lidar In-Space Technology Experiment

    Chang, John; Cimolino, Marc; Petros, Mulugeta

    1991-01-01

    The Lidar In-Space Technology Experiment (LITE) Laser Transmitter Module (LTM) flight laser optical architecture has been space qualified by extensive testing at the system, subsystem and component level. The projected system output performance has been verified using an optically and electrically similar breadboard version of the laser. Parasitic lasing was closely examined and completely suppressed after design changes were implemented and tested. Oscillator and amplifier type heads were separately tested to 150 million shots. Critical subassemblies have undergone environmental testing to Shuttle qualification levels. A superior three color anti-reflection coating was developed and tested for use on 14 surfaces after the final amplifier.

  19. Fiber Optic Surface Plasmon Resonance-Based Biosensor Technique: Fabrication, Advancement, and Application.

    Liang, Gaoling; Luo, Zewei; Liu, Kunping; Wang, Yimin; Dai, Jianxiong; Duan, Yixiang

    2016-05-03

    Fiber optic-based biosensors with surface plasmon resonance (SPR) technology are advanced label-free optical biosensing methods. They have brought tremendous progress in the sensing of various chemical and biological species. This review summarizes four sensing configurations (prism, grating, waveguide, and fiber optic) with two ways, attenuated total reflection (ATR) and diffraction, to excite the surface plasmons. Meanwhile, the designs of different probes (U-bent, tapered, and other probes) are also described. Finally, four major types of biosensors, immunosensor, DNA biosensor, enzyme biosensor, and living cell biosensor, are discussed in detail for their sensing principles and applications. Future prospects of fiber optic-based SPR sensor technology are discussed.

  20. Legal and Regulatroy Obstacles to Nuclear Fission Technology in Space

    Force, Melissa K.

    2013-09-01

    In forecasting the prospective use of small nuclear reactors for spacecraft and space-based power stations, the U.S. Air Force describes space as "the ultimate high ground," providing access to every part of the globe. But is it? A report titled "Energy Horizons: United States Air Force Energy Science &Technology Vision 2011-2026," focuses on core Air Force missions in space energy generation, operations and propulsion and recognizes that investments into small modular nuclear fission reactors can be leveraged for space-based systems. However, the report mentions, as an aside, that "potential catastrophic outcomes" are an element to be weighed and provides no insight into the monumental political and legal will required to overcome the mere stigma of nuclear energy, even when referring only to the most benign nuclear power generation systems - RTGs. On the heels of that report, a joint Department of Energy and NASA team published positive results from the demonstration of a uranium- powered fission reactor. The experiment was perhaps most notable for exemplifying just how effective the powerful anti-nuclear lobby has been in the United States: It was the first such demonstration of its kind in nearly fifty years. Space visionaries must anticipate a difficult war, consisting of multiple battles that must be waged in order to obtain a license to fly any but the feeblest of nuclear power sources in space. This paper aims to guide the reader through the obstacles to be overcome before nuclear fission technology can be put to use in space.

  1. Robotic Technology Efforts at the NASA/Johnson Space Center

    Diftler, Ron

    2017-01-01

    The NASA/Johnson Space Center has been developing robotic systems in support of space exploration for more than two decades. The goal of the Center’s Robotic Systems Technology Branch is to design and build hardware and software to assist astronauts in performing their mission. These systems include: rovers, humanoid robots, inspection devices and wearable robotics. Inspection systems provide external views of space vehicles to search for surface damage and also maneuver inside restricted areas to verify proper connections. New concepts in human and robotic rovers offer solutions for navigating difficult terrain expected in future planetary missions. An important objective for humanoid robots is to relieve the crew of “dull, dirty or dangerous” tasks allowing them more time to perform their important science and exploration missions. Wearable robotics one of the Center’s newest development areas can provide crew with low mass exercise capability and also augment an astronaut’s strength while wearing a space suit.This presentation will describe the robotic technology and prototypes developed at the Johnson Space Center that are the basis for future flight systems. An overview of inspection robots will show their operation on the ground and in-orbit. Rovers with independent wheel modules, crab steering, and active suspension are able to climb over large obstacles, and nimbly maneuver around others. Humanoid robots, including the First Humanoid Robot in Space: Robonaut 2, demonstrate capabilities that will lead to robotic caretakers for human habitats in space, and on Mars. The Center’s Wearable Robotics Lab supports work in assistive and sensing devices, including exoskeletons, force measuring shoes, and grasp assist gloves.

  2. Wicked problems in space technology development at NASA

    Balint, Tibor S.; Stevens, John

    2016-01-01

    Technological innovation is key to enable future space exploration missions at NASA. Technology development, however, is not only driven by performance and resource considerations, but also by a broad range of directly or loosely interconnected factors. These include, among others, strategy, policy and politics at various levels, tactics and programmatics, interactions between stakeholders, resource requirements, performance goals from component to system level, mission infusion targets, portfolio execution and tracking, and technology push or mission pull. Furthermore, at NASA, these influences occur on varying timescales and at diverse geographic locations. Such a complex and interconnected system could impede space technology innovation in this examined segment of the government environment. Hence, understanding the process through NASA's Planning, Programming, Budget and Execution cycle could benefit strategic thinking, planning and execution. Insights could be gained through suitable models, for example assessing the key drivers against the framework of Wicked Problems. This paper discusses NASA specific space technology innovation and innovation barriers in the government environment through the characteristics of Wicked Problems; that is, they do not have right or wrong solutions, only improved outcomes that can be reached through authoritative, competitive, or collaborative means. We will also augment the Wicked Problems model to account for the temporally and spatially coupled, and cyclical nature of this NASA specific case, and propose how appropriate models could improve understanding of the key influencing factors. In turn, such understanding may subsequently lead to reducing innovation barriers, and stimulating technology innovation at NASA. Furthermore, our approach can be adopted for other government-directed environments to gain insights into their structures, hierarchies, operational flow, and interconnections to facilitate circular dialogs towards

  3. Millimeter-Wave Wireless Power Transfer Technology for Space Applications

    Chattopadhyay, Goutam; Manohara, Harish; Mojarradi, Mohammad M.; Vo, Tuan A.; Mojarradi, Hadi; Bae, Sam Y.; Marzwell, Neville

    2008-01-01

    In this paper we present a new compact, scalable, and low cost technology for efficient receiving of power using RF waves at 94 GHz. This technology employs a highly innovative array of slot antennas that is integrated on substrate composed of gold (Au), silicon (Si), and silicon dioxide (SiO2) layers. The length of the slots and spacing between them are optimized for a highly efficient beam through a 3-D electromagnetic simulation process. Antenna simulation results shows a good beam profile with very low side lobe levels and better than 93% antenna efficiency.

  4. Space Environmental Testing of the Electrodynamic Dust Shield Technology

    Calle, Carlos I.; Mackey, P. J.; Hogue, M. D.; Johansen, M .R.; Yim, H.; Delaune, P. B.; Clements, J. S.

    2013-01-01

    NASA's exploration missions to Mars and the moon may be jeopardized by dust that will adhere to surfaces of (a) Optical systems, viewports and solar panels, (b) Thermal radiators, (c) Instrumentation, and (d) Spacesuits. We have developed an active dust mitigation technology, the Electrodynamic Dust Shield, a multilayer coating that can remove dust and also prevents its accumulation Extensive testing in simulated laboratory environments and on a reduced gravity flight shows that high dust removal performance can be achieved Long duration exposure to the space environment as part of the MISSE-X payload will validate the technology for lunar missions.

  5. Future NASA Power Technologies for Space and Aero Propulsion Applications

    Soeder, James F.

    2015-01-01

    To achieve the ambitious goals that NASA has outlined for the next decades considerable development of power technology will be necessary. This presentation outlines the development objectives for both space and aero applications. It further looks at the various power technologies that support these objectives and examines drivers that will be a driving force for future development. Finally, the presentation examines what type of non-traditional learning areas should be emphasized in student curriculum so that the engineering needs of the third decade of the 21st Century are met.

  6. Novel Design Aspects of the Space Technology 5 Mechanical Subsystem

    Rossoni, Peter; McGill, William

    2003-01-01

    This paper describes several novel design elements of the Space Technology 5 (ST5) spacecraft mechanical subsystem. The spacecraft structure itself takes a significant step in integrating electronics into the primary structure. The deployment system restrains the spacecraft during launch and imparts a predetermined spin rate upon release from its secondary payload accommodations. The deployable instrument boom incorporates some traditional as well as new techniques for lightweight and stiffness. Analysis and test techniques used to validate these technologies are described. Numerous design choices were necessitated due to the compact spacecraft size and strict mechanical subsystem requirements.

  7. Technical and Economical study of New Technologies and Reusable Space Vehicles promoting Space Tourism.

    Srivastav, Deepanshu; Malhotra, Sahil

    2012-07-01

    For many of us space tourism is an extremely fascinating and attractive idea. But in order for these to start we need vehicles that will take us to orbit and bring us back. Current space vehicles clearly cannot. Only the Space Shuttle survives past one use, and that's only if we ignore the various parts that fall off on the way up. So we need reusable launch vehicles. Launch of these vehicles to orbit requires accelerating to Mach 26, and therefore it uses a lot of propellant - about 10 tons per passenger. But there is no technical reason why reusable launch vehicles couldn't come to be operated routinely, just like aircraft. The main problem about space is how much it costs to get there, it's too expensive. And that's mainly because launch vehicles are expendable - either entirely, like satellite launchers, or partly, like the space shuttle. The trouble is that these will not only reduce the cost of launch - they'll also put the makers out of business, unless there's more to launch than just a few satellites a year, as there are today. Fortunately there's a market that will generate far more launch business than satellites ever well - passenger travel. This paper assesses this emerging market as well as technology that will make space tourism feasible. The main conclusion is that space vehicles can reduce the cost of human transport to orbit sufficiently for large new commercial markets to develop. Combining the reusability of space vehicles with the high traffic levels of space tourism offers the prospect of a thousandfold reduction in the cost per seat to orbit. The result will be airline operations to orbit involving dozens of space vehicles, each capable of more than one flight per day. These low costs will make possible a rapid expansion of space science and exploration. Luckily research aimed at developing low-cost reusable launch vehicles has increased recently. Already there are various projects like Spaceshipone, Spaceshiptwo, Spacebus, X-33 NASA etc. The

  8. Thermionic integrated circuit technology for high power space applications

    Yadavalli, S.R.

    1984-01-01

    Thermionic triode and integrated circuit technology is in its infancy and it is emerging. The Thermionic triode can operate at relatively high voltages (up to 2000V) and at least tens of amperes. These devices, including their use in integrated circuitry, operate at high temperatures (800 0 C) and are very tolerant to nuclear and other radiations. These properties can be very useful in large space power applications such as that represented by the SP-100 system which uses a nuclear reactor. This paper presents an assessment of the application of thermionic integrated circuitry with space nuclear power system technology. A comparison is made with conventional semiconductor circuitry considering a dissipative shunt regulator for SP-100 type nuclear power system rated at 100 kW. The particular advantages of thermionic circuitry are significant reductions in size and mass of heat dissipation and radiation shield subsystems

  9. Space Solar Power Technology for Lunar Polar Applications

    Henley, Mark W.; Howell, Joe T.

    2004-01-01

    The technology for Laser-Photo-Voltaic Wireless Power Transistor (Laser-PV WPT) is being developed for lunar polar applications by Boeing and NASA Marshall Space Center. A lunar polar mission could demonstrate and validate Laser-PV WPT and other SSP technologies, while enabling access to cold, permanently shadowed craters that are believed to contain ice. Crater may hold frozen water and other volatiles deposited over billion of years, recording prior impact event on the moon (and Earth). A photo-voltaic-powered rover could use sunlight, when available, and laser light, when required, to explore a wide range of lunar terrain. The National Research Council recently found that a mission to the moon's south pole-Aitkir basin has priority for space science

  10. Mathematical Model of Plasma Space for Electronic Technologies

    N.N. Chernyshov; K.T. Umyarov; D.V. Pisarenko

    2014-01-01

    The paper is devoted to studying the plasma used in technologies of the electronic industry. It gives the characteristic of plasma space on the basis of a system of Maxwell-Boltzmann equa-tions. Solving these equations is represented in the form of Fourier transformation and Green functions. Fluctuation-dissipative theorem and method of Longevin sources for calculating electric filed fluctua-tions are used.

  11. Monolithic microwave integrated circuit technology for advanced space communication

    Ponchak, George E.; Romanofsky, Robert R.

    1988-01-01

    Future Space Communications subsystems will utilize GaAs Monolithic Microwave Integrated Circuits (MMIC's) to reduce volume, weight, and cost and to enhance system reliability. Recent advances in GaAs MMIC technology have led to high-performance devices which show promise for insertion into these next generation systems. The status and development of a number of these devices operating from Ku through Ka band will be discussed along with anticipated potential applications.

  12. Solar pumped laser technology options for space power transmission

    Conway, E. J.

    1986-01-01

    An overview of long-range options for in-space laser power transmission is presented. The focus is on the new technology and research status of solar-pumped lasers and their solar concentration needs. The laser options include gas photodissociation lasers, optically-pumped solid-state lasers, and blackbody-pumped transfer lasers. The paper concludes with a summary of current research thrusts.

  13. Advanced Mirror Technology Development for Very Large Space Telescopes

    Stahl, H. P.

    2014-01-01

    Advanced Mirror Technology Development (AMTD) is a NASA Strategic Astrophysics Technology project to mature to TRL-6 the critical technologies needed to produce 4-m or larger flight-qualified UVOIR mirrors by 2018 so that a viable mission can be considered by the 2020 Decadal Review. The developed mirror technology must enable missions capable of both general astrophysics & ultra-high contrast observations of exoplanets. Just as JWST’s architecture was driven by launch vehicle, a future UVOIR mission’s architectures (monolithic, segmented or interferometric) will depend on capacities of future launch vehicles (and budget). Since we cannot predict the future, we must prepare for all potential futures. Therefore, to provide the science community with options, we are pursuing multiple technology paths. AMTD uses a science-driven systems engineering approach. We derived engineering specifications for potential future monolithic or segmented space telescopes based on science needs and implement constraints. And we are maturing six inter-linked critical technologies to enable potential future large aperture UVOIR space telescope: 1) Large-Aperture, Low Areal Density, High Stiffness Mirrors, 2) Support Systems, 3) Mid/High Spatial Frequency Figure Error, 4) Segment Edges, 5) Segment-to-Segment Gap Phasing, and 6) Integrated Model Validation Science Advisory Team and a Systems Engineering Team. We are maturing all six technologies simultaneously because all are required to make a primary mirror assembly (PMA); and, it is the PMA’s on-orbit performance which determines science return. PMA stiffness depends on substrate and support stiffness. Ability to cost-effectively eliminate mid/high spatial figure errors and polishing edges depends on substrate stiffness. On-orbit thermal and mechanical performance depends on substrate stiffness, the coefficient of thermal expansion (CTE) and thermal mass. And, segment-to-segment phasing depends on substrate & structure stiffness

  14. Overcoming Learning Time And Space Constraints Through Technological Tool

    Nafiseh Zarei

    2015-08-01

    Full Text Available Today the use of technological tools has become an evolution in language learning and language acquisition. Many instructors and lecturers believe that integrating Web-based learning tools into language courses allows pupils to become active learners during learning process. This study investigate how the Learning Management Blog (LMB overcomes the learning time and space constraints that contribute to students’ language learning and language acquisition processes. The participants were 30 ESL students at National University of Malaysia. A qualitative approach comprising an open-ended questionnaire and a semi-structured interview was used to collect data. The results of the study revealed that the students’ language learning and acquisition processes were enhanced. The students did not face any learning time and space limitations while being engaged in the learning process via the LMB. They learned and acquired knowledge using the language learning materials and forum at anytime and anywhere. Keywords: learning time, learning space, learning management blog

  15. Use of a Lunar Outpost for Developing Space Settlement Technologies

    Purves, Lloyd R.

    2008-01-01

    The type of polar lunar outpost being considered in the NASA Vision for Space Exploration (VSE) can effectively support the development of technologies that will not only significantly enhance lunar exploration, but also enable long term crewed space missions, including space settlement. The critical technologies are: artificial gravity, radiation protection, Closed Ecological Life Support Systems (CELSS) and In-Situ Resource Utilization (ISRU). These enhance lunar exploration by extending the time an astronaut can remain on the moon and reducing the need for supplies from Earth, and they seem required for space settlement. A polar lunar outpost provides a location to perform the research and testing required to develop these technologies, as well as to determine if there are viable countermeasures that can reduce the need for Earth-surface-equivalent gravity and radiation protection on long human space missions. The types of spinning space vehicles or stations envisioned to provide artificial gravity can be implemented and tested on the lunar surface, where they can create any level of effective gravity above the 1/6 Earth gravity that naturally exists on the lunar surface. Likewise, varying degrees of radiation protection can provide a natural radiation environment on the lunar surface less than or equal to 1/2 that of open space at 1 AU. Lunar ISRU has the potential of providing most of the material needed for radiation protection, the centrifuge that provides artificial gravity; and the atmosphere, water and soil for a CELSS. Lunar ISRU both saves the cost of transporting these materials from Earth and helps define the requirements for ISRU on other planetary bodies. Biosphere II provides a reference point for estimating what is required for an initial habitat with a CELSS. Previous studies provide initial estimates of what would be required to provide such a lunar habitat with the gravity and radiation environment of the Earth s surface. While much preparatory

  16. Technology assessment for Spaceship Two, space tourism, and private spaceflight

    Hancock, Randy

    A seven-step technology assessment was conducted to address questions regarding the significance and likely consequences associated with the introduction of Spaceship Two, space tourism, and private spaceflight. Impacts were assessed across four categories: the Role and Functions of Government, Private Industry Factors, Cultural and Societal Impacts, and the Time Frame in which these impacts were anticipated to occur. The technology assessment findings were compared to the results of expert interviews that addressed the sane four categories. The researcher noted that, while there was overwhelming agreement between the technology assessment's primary impacts and the expert interview responses, there were several differences. The technology assessment and interviewees agreed that the federal government would likely be both a regulator and user of private spaceflight. Both agreed that business partnerships would be key in pursuing private spaceflight. There was also consensus that, as market forces come to bear, ticket prices would drop and a larger market and broader passenger demographic would emerge. The technology assessment and experts agreed that an accident, especially one early in the industry's evolution, could be disastrous. Both agreed that private spaceflight can serve as a inspiration to students and be a positive influence in society, and both agreed that the start of passenger flights should take place in the 2010 - 2012 timeframe. Due to the potentially disastrous consequences of an accident, there was agreement between the technology assessment and experts on the value of flight and ground crew training, driven by insurance carriers and federal mandate. Most differences between the technology assessment's findings and the expert interview responses were due to omission, rather than direct disagreement. However, this was not the case in every instance. The most significant difference between the technology assessment and the experts involved the

  17. Assembly of Space CFRP Structures with Racing Sailing Boats Technology

    Nieto, Jose; Yuste, Laura; Pipo, Alvaro; Santarsiero, Pablo; Bureo, Rafael

    2014-06-01

    Carbon Fiber Reinforced Plastic (CFRP) is commonly used in space applications to get structures with good mechanical performances and a reduced mass. Most of larger parts of spatial structures are already made of CFRP but the achieved weight saving may be jeopardized by the use of metallic brackets as joining elements. This paper describes the work carried out to study and evaluate ways of reducing weight and costs of the joints between structural elements commonly used in space applications.The main objective of this project is to adapt design solutions coming from the racing sailing boats technology to space applications: the use of out-of autoclave (OoA) cured CFRP joints. In addition to that other CFRP solution common in space business, 3D- RTM Bracket, has been evaluated.This development studies the manufacturing and assembly feasibility making use of these CFRP technologies.This study also compares traditional metallic solutions with innovative CFRP ones in terms of mechanical performances at elementary level. Weight and cost of presented solutions are also compared.

  18. Cold Atmospheric Plasma Technology for Decontamination of Space Equipment

    Thomas, Hubertus; Rettberg, Petra; Shimizu, Tetsuji; Thoma, Markus; Morfill, Gregor; Zimmermann, Julia; Müller, Meike; Semenov, Igor

    2016-07-01

    Cold atmospheric plasma (CAP) technology is very fast and effective in inactivation of all kinds of pathogens. It is used in hygiene and especially in medicine, since the plasma treatment can be applied to sensitive surfaces, like skin, too. In a first study to use CAP for the decontamination of space equipment we could show its potential as a quite promising alternative to the standard "dry heat" and H2O2 methods [Shimizu et al. Planetary and Space Science, 90, 60-71. (2014)]. In a follow-on study we continue the investigations to reach high application level of the technology. First, we redesign the actual setup to a plasma-gas circulation system, increasing the effectivity of inactivation and the sustainability. Additionally, we want to learn more about the plasma chemistry processes involved in the inactivation. Therefore, we perform detailed plasma and gas measurements and compare them to numerical simulations. The latter will finally be used to scale the decontamination system to sizes useful also for larger space equipment. Typical materials relevant for space equipment will be tested and investigated on surface material changes due to the plasma treatment. Additionally, it is planned to use electronic boards and compare their functionality before and after the CAP expose. We will give an overview on the status of the plasma decontamination project funded by the Bavarian Ministry of Economics.

  19. Technology Assessment of Laser-Assisted Materials Processing in Space

    Nagarathnam, Karthik; Taminger, Karen M. B.

    2001-01-01

    Lasers are useful for performing operations such as joining, machining, built-up freeform fabrication, shock processing, and surface treatments. These attributes are attractive for the supportability of longer-term missions in space due to the multi-functionality of a single tool and the variety of materials that can be processed. However, current laser technology also has drawbacks for space-based applications, specifically size, power efficiency, lack of robustness, and problems processing highly reflective materials. A review of recent laser developments will be used to show how these issues may be reduced and indicate where further improvement is necessary to realize a laser-based materials processing capability in space. The broad utility of laser beams in synthesizing various classes of engineering materials will be illustrated using state-of-the art processing maps for select lightweight alloys typically found on spacecraft. With the advent of recent breakthroughs in diode-pumped solid-state lasers and fiber optic technologies, the potential to perform multiple processing techniques is increasing significantly. Lasers with suitable wavelengths and beam properties have tremendous potential for supporting future space missions to the moon, Mars and beyond.

  20. Exploration Space Suit Architecture: Destination Environmental-Based Technology Development

    Hill, Terry R.

    2010-01-01

    This paper picks up where EVA Space Suit Architecture: Low Earth Orbit Vs. Moon Vs. Mars (Hill, Johnson, IEEEAC paper #1209) left off in the development of a space suit architecture that is modular in design and interfaces and could be reconfigured to meet the mission or during any given mission depending on the tasks or destination. This paper will walk though the continued development of a space suit system architecture, and how it should evolve to meeting the future exploration EVA needs of the United States space program. In looking forward to future US space exploration and determining how the work performed to date in the CxP and how this would map to a future space suit architecture with maximum re-use of technology and functionality, a series of thought exercises and analysis have provided a strong indication that the CxP space suit architecture is well postured to provide a viable solution for future exploration missions. Through the destination environmental analysis that is presented in this paper, the modular architecture approach provides the lowest mass, lowest mission cost for the protection of the crew given any human mission outside of low Earth orbit. Some of the studies presented here provide a look and validation of the non-environmental design drivers that will become every-increasingly important the further away from Earth humans venture and the longer they are away. Additionally, the analysis demonstrates a logical clustering of design environments that allows a very focused approach to technology prioritization, development and design that will maximize the return on investment independent of any particular program and provide architecture and design solutions for space suit systems in time or ahead of being required for any particular manned flight program in the future. The new approach to space suit design and interface definition the discussion will show how the architecture is very adaptable to programmatic and funding changes with

  1. Communicating with the public: space of nuclear technology

    Maffei, Patricia Martinez; Aquino, Afonso Rodrigues; Gordon, Ana Maria Pinho Leite; Oliveira, Rosana Lagua de; Padua, Rafael Vicente de; Vieira, Martha Marques Ferreira; Vicente, Roberto, E-mail: pmaffei@ipen.br, E-mail: araquino@usp.br, E-mail: amgordon@ipen.br, E-mail: rloliveira@ipen.br, E-mail: rpadua@ipen.br, E-mail: mmvieira@ipen.br, E-mail: rvicente@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    For two decades the Nuclear and Energy Research Institute (IPEN) has been developing activities for popularization of its R and D activities in the nuclear field. Some of the initiatives already undertaken by IPEN are lectures at schools, guided visits to IPEN facilities, printed informative material, FAQ page in the Web, and displays in annual meetings and technology fairs highlighting its achievements. In order to consolidate these initiatives, IPEN is planning to have a permanent Space of Nuclear Technology (SNT), aiming at introducing students, teachers and the general public to the current applications of nuclear technology in medicine, industry, research, electric power generation, etc. It is intended as an open room to the public and will have a permanent exhibit with historical, scientific, technical and cultural developments of nuclear technology and will also feature temporary exhibitions about specific themes. The space will display scientific material in different forms to allow conducting experiments to demonstrate some of the concepts associated with the properties of nuclear energy, hands-on programs and activities that can be customized to the students' grade level and curriculum. (author)

  2. Space Missions for Automation and Robotics Technologies (SMART) Program

    Cliffone, D. L.; Lum, H., Jr.

    1985-01-01

    NASA is currently considering the establishment of a Space Mission for Automation and Robotics Technologies (SMART) Program to define, develop, integrate, test, and operate a spaceborne national research facility for the validation of advanced automation and robotics technologies. Initially, the concept is envisioned to be implemented through a series of shuttle based flight experiments which will utilize telepresence technologies and real time operation concepts. However, eventually the facility will be capable of a more autonomous role and will be supported by either the shuttle or the space station. To ensure incorporation of leading edge technology in the facility, performance capability will periodically and systematically be upgraded by the solicitation of recommendations from a user advisory group. The facility will be managed by NASA, but will be available to all potential investigators. Experiments for each flight will be selected by a peer review group. Detailed definition and design is proposed to take place during FY 86, with the first SMART flight projected for FY 89.

  3. Communicating with the public: space of nuclear technology

    Maffei, Patricia Martinez; Aquino, Afonso Rodrigues; Gordon, Ana Maria Pinho Leite; Oliveira, Rosana Lagua de; Padua, Rafael Vicente de; Vieira, Martha Marques Ferreira; Vicente, Roberto

    2011-01-01

    For two decades the Nuclear and Energy Research Institute (IPEN) has been developing activities for popularization of its R and D activities in the nuclear field. Some of the initiatives already undertaken by IPEN are lectures at schools, guided visits to IPEN facilities, printed informative material, FAQ page in the Web, and displays in annual meetings and technology fairs highlighting its achievements. In order to consolidate these initiatives, IPEN is planning to have a permanent Space of Nuclear Technology (SNT), aiming at introducing students, teachers and the general public to the current applications of nuclear technology in medicine, industry, research, electric power generation, etc. It is intended as an open room to the public and will have a permanent exhibit with historical, scientific, technical and cultural developments of nuclear technology and will also feature temporary exhibitions about specific themes. The space will display scientific material in different forms to allow conducting experiments to demonstrate some of the concepts associated with the properties of nuclear energy, hands-on programs and activities that can be customized to the students' grade level and curriculum. (author)

  4. Wireless Technology Use Case Requirement Analysis for Future Space Applications

    Abedi, Ali; Wilkerson, DeLisa

    2016-01-01

    This report presents various use case scenarios for wireless technology -including radio frequency (RF), optical, and acoustic- and studies requirements and boundary conditions in each scenario. The results of this study can be used to prioritize technology evaluation and development and in the long run help in development of a roadmap for future use of wireless technology. The presented scenarios cover the following application areas: (i) Space Vehicles (manned/unmanned), (ii) Satellites and Payloads, (iii) Surface Explorations, (iv) Ground Systems, and (v) Habitats. The requirement analysis covers two parallel set of conditions. The first set includes the environmental conditions such as temperature, radiation, noise/interference, wireless channel characteristics and accessibility. The second set of requirements are dictated by the application and may include parameters such as latency, throughput (effective data rate), error tolerance, and reliability. This report provides a comprehensive overview of all requirements from both perspectives and details their effects on wireless system reliability and network design. Application area examples are based on 2015 NASA Technology roadmap with specific focus on technology areas: TA 2.4, 3.3, 5.2, 5.5, 6.4, 7.4, and 10.4 sections that might benefit from wireless technology.

  5. In-space research, technology and engineering experiments and Space Station

    Tyson, Richard; Gartrell, Charles F.

    1988-01-01

    The NASA Space Station will serve as a technology research laboratory, a payload-servicing facility, and a large structure fabrication and assembly facility. Space structures research will encompass advanced structural concepts and their dynamics, advanced control concepts, sensors, and actuators. Experiments dealing with fluid management will gather data on such fundamentals as multiphase flow phenomena. As requirements for power systems and thermal management grow, experiments quantifying the performance of energy systems and thermal management concepts will be undertaken, together with expanded efforts in the fields of information systems, automation, and robotics.

  6. The development and technology transfer of software engineering technology at NASA. Johnson Space Center

    Pitman, C. L.; Erb, D. M.; Izygon, M. E.; Fridge, E. M., III; Roush, G. B.; Braley, D. M.; Savely, R. T.

    1992-01-01

    The United State's big space projects of the next decades, such as Space Station and the Human Exploration Initiative, will need the development of many millions of lines of mission critical software. NASA-Johnson (JSC) is identifying and developing some of the Computer Aided Software Engineering (CASE) technology that NASA will need to build these future software systems. The goal is to improve the quality and the productivity of large software development projects. New trends are outlined in CASE technology and how the Software Technology Branch (STB) at JSC is endeavoring to provide some of these CASE solutions for NASA is described. Key software technology components include knowledge-based systems, software reusability, user interface technology, reengineering environments, management systems for the software development process, software cost models, repository technology, and open, integrated CASE environment frameworks. The paper presents the status and long-term expectations for CASE products. The STB's Reengineering Application Project (REAP), Advanced Software Development Workstation (ASDW) project, and software development cost model (COSTMODL) project are then discussed. Some of the general difficulties of technology transfer are introduced, and a process developed by STB for CASE technology insertion is described.

  7. Space Solar Power Technology Demonstration for Lunar Polar Applications

    Henley, M. W.; Fikes, J. C.; Howell, J.; Mankins, J. C.; Howell, J.

    2002-01-01

    A solar power generation station on a mountaintop near the moon's North or South pole can receive sunlight 708 hours per lunar day, for continuous power generation. Power can be beamed from this station over long distances using a laser-based wireless power transmission system and a photo-voltaic receiver. This beamed energy can provide warmth, electricity, and illumination for a robotic rover to perform scientific experiments in cold, dark craters where no other power source is practical. Radio-frequency power transmission may also be demonstrated in lunar polar applications to locate and recover sub-surface deposits of volatile material, such as water ice. High circular polarization ratios observed in data from Clementine spacecraft and Arecibo radar reflections from the moon's South pole suggest that water ice is indeed present in certain lunar polar craters. Data from the Lunar Prospector spacecraft's epi-thermal neutron spectrometer also indicate that hydrogen is present at the moon's poles. Space Solar Power technology enables investigation of these craters, which may contain a billion-year-old stratigraphic record of tremendous scientific value. Layers of ice, preserved at the moon's poles, could help us determine the sequence and composition of comet impacts on the moon. Such ice deposits may even include distinct strata deposited by secondary ejecta following significant Earth (ocean) impacts, linked to major extinctions of life on Earth. Ice resources at the moon's poles could provide water and air for human exploration and development of space as well as rocket propellant for future space transportation. Technologies demonstrated and matured via lunar polar applications can also be used in other NASA science missions (Valles Marineris. Phobos, Deimos, Mercury's poles, asteroids, etc.) and in future large-scale SSP systems to beam energy from space to Earth. Ground-based technology demonstrations are proceeding to mature the technology for such a near

  8. On-Orbit Measurement of Next Generation Space Solar Cell Technology on the International Space Station

    Wolford, David S.; Myers, Matthew G.; Prokop, Norman F.; Krasowski, Michael J.; Parker, David S.; Cassidy, Justin C.; Davies, William E.; Vorreiter, Janelle O.; Piszczor, Michael F.; McNatt, Jeremiah S.

    2015-01-01

    Measurement is essential for the evaluation of new photovoltaic (PV) technology for space solar cells. NASA Glenn Research Center (GRC) is in the process of measuring several solar cells in a supplemental experiment on NASA Goddard Space Flight Center's (GSFC) Robotic Refueling Mission's (RRM) Task Board 4 (TB4). Four industry and government partners have provided advanced PV devices for measurement and orbital environment testing. The experiment will be on-orbit for approximately 18 months. It is completely self-contained and will provide its own power and internal data storage. Several new cell technologies including four- junction (4J) Inverted Metamorphic Multijunction (IMM) cells will be evaluated and the results compared to ground-based measurements.

  9. Terrestrial Micro Renewable Energy Applications of Space Technology

    Komerath, N. M.; Komerath, P. P.

    This paper explores the synergy between technologies intended for extraterrestrial in situ resource utilization and those for terrestrial mass-market micro renewable power generation systems. The case for a micro renewable energy architecture is presented. The obstacles hindering market success are summarized, along with opportunities from recent demonstrations suggesting that the public appetite for sophisticated technology worldwide may be underappreciated by technical researchers. Technical innovations from space research are summarized along with estimates of possible conversion efficiencies. It is argued that the cost-effectiveness of micro power generation must be viewed through the value of the first few watts of available power, rather than the marginal cost per kilowatt-hour of electric power from utility power grids. This leads to the finding that the actual target cost per unit power, and efficiency, are well within reach of space technology products. Hybrid systems integrating power extraction from multiple resources, and adaptable for multiple applications, can break through mass market price barriers. Recent work to develop learning resources and test beds as part of a Micro Renewable Energy Laboratory is summarized.

  10. Technology development for nuclear power generation for space application

    Guimaraes, Lamartine N.F.; Ribeiro, Guilherme B.; Braz Filho, Francisco A.; Nascimento, Jamil A.; Placco, Guilherme M.

    2015-01-01

    For a few years now, the TERRA project is developing several technology pieces to foster nuclear space applications. In this way, a nuclear reactor concept has been developed as a first proposal. Together, the problem of heat to electricity conversion has been addressed. A closed Brayton cycle is being built and a Stirling machine is being worked out and perfected. In addition, two types of heat pipes are being look at. One related with high temperature made of Mo13Re, an especial alloy. And a second one made of copper, which mainly could be used as a passive heat rejection. In this way, all major areas of interest in a micro station to be used in space has been addressed. A new passive technology has been inferred and is related with Tesla turbine or its evolution, known as multi fluid passive turbine. This technology has the potential to either: improve the Brayton cycle or its efficiency. In this paper, some details are discussed and some will be shown during the presentation, as the work evolve. (author)

  11. Technology development for nuclear power generation for space application

    Guimaraes, Lamartine N.F.; Ribeiro, Guilherme B.; Braz Filho, Francisco A.; Nascimento, Jamil A.; Placco, Guilherme M., E-mail: guimarae@ieav.cta.br, E-mail: lamartine.guimaraes@pq.cnpq.br [Instituto de Estudos Avancados (IEAv), Sao Jose dos Campos, SP (Brazil). Divisao de Energia Nuclear; Faria, Saulo M. de [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos, SP (Brazil)

    2015-07-01

    For a few years now, the TERRA project is developing several technology pieces to foster nuclear space applications. In this way, a nuclear reactor concept has been developed as a first proposal. Together, the problem of heat to electricity conversion has been addressed. A closed Brayton cycle is being built and a Stirling machine is being worked out and perfected. In addition, two types of heat pipes are being look at. One related with high temperature made of Mo13Re, an especial alloy. And a second one made of copper, which mainly could be used as a passive heat rejection. In this way, all major areas of interest in a micro station to be used in space has been addressed. A new passive technology has been inferred and is related with Tesla turbine or its evolution, known as multi fluid passive turbine. This technology has the potential to either: improve the Brayton cycle or its efficiency. In this paper, some details are discussed and some will be shown during the presentation, as the work evolve. (author)

  12. Developing hybrid near-space technologies for affordable access to suborbital space

    Badders, Brian David

    High power rockets and high altitude balloons are two near-space technologies that could be combined in order to provide access to the mesosphere and, eventually, suborbital space. This "rockoon" technology has been used by several large budget space programs before being abandoned in favor of even more expensive, albeit more accurate, ground launch systems. With the increased development of nano-satellites and atmospheric sensors, combined with rising interest in global atmospheric data, there is an increase in desire for affordable access to extreme altitudes that does not necessarily require the precision of ground launches. Development of hybrid near-space technologies for access to over 200k ft. on a small budget brings many challenges within engineering, systems integration, cost analysis, market analysis, and business planning. This research includes the design and simulation testing of all the systems needed for a safe and reusable launch system, the cost analysis for initial production, the development of a business plan, and the development of a marketing plan. This project has both engineering and scientific significance in that it can prove the space readiness of new technologies, raise their technology readiness levels (TRLs), expedite the development process, and also provide new data to the scientific community. It also has the ability to stimulate university involvement in the aerospace industry and help to inspire the next generation of workers in the space sector. Previous development of high altitude balloon/high power rocket hybrid systems have been undertaken by government funded military programs or large aerospace corporations with varying degrees of success. However, there has yet to be a successful flight with this type of system which provides access to the upper mesosphere in a university setting. This project will aim to design and analyze a viable system while testing the engineering process under challenging budgetary constraints. The

  13. Modal survey testing of the Lidar In-space Technology Experiment (LITE) - A Space Shuttle payload

    Anderson, J. B.; Coleman, A. D.; Driskill, T. C.; Lindell, M. C.

    This paper presents the results of the modal survey test of the Lidar In-space Technology Experiment (LITE), a Space Shuttle payload mounted in a Spacelab flight single pallet. The test was performed by the Dynamics Test Branch at Marshall Space Flight Center, AL and run in two phases. In the first phase, an unloaded orthogrid connected to the pallet with 52 tension struts was tested. This test included 73 measurement points in three directions. In the second phase, the pallet was integrated with mass simulators mounted on the flight support structure to represent the dynamics (weight and center of gravity) of the various components comprising the LITE experiment and instrumented at 213 points in 3 directions. The test article was suspended by an air bag system to simulate a free-free boundary condition. This paper presents the results obtained from the testing and analytical model correlation efforts. The effect of the suspension system on the test article is also discussed.

  14. Space Qualified Non-Destructive Evaluation and Structural Health Monitoring Technology, Phase I

    National Aeronautics and Space Administration — NextGen Aeronautics is proposing an innovative space qualified non-destructive evaluation and health monitoring technology. The technology is built on concepts...

  15. Development of FRET biosensors for mammalian and plant systems

    Hamers, D.; van Voorst Vader, L.; Borst, J.W.; Goedhart, J.

    2014-01-01

    Genetically encoded biosensors are increasingly used in visualising signalling processes in different organisms. Sensors based on green fluorescent protein technology are providing a great opportunity for using Forster resonance energy transfer (FRET) as a tool that allows for monitoring dynamic

  16. The NASA research and technology program on space power: A key element of the Space Exploration Initiative

    Bennett, Gary L.; Brandhorst, Henry W., Jr.; Atkins, Kenneth L.

    1991-01-01

    In July 1989, President Bush announced his space exploration initiative of going back to the Moon to stay and then going to Mars. Building upon its ongoing research and technology base, NASA has established an exploration technology program to develop the technologies needed for piloted missions to the Moon and Mars. A key element for the flights and for the planned bases is power. The NASA research and technology program on space power encompasses power sources, energy storage, and power management.

  17. Distress detection, location, and communications using advanced space technology

    Sivertson, W. E., Jr.

    1977-01-01

    This paper briefly introduces a concept for low-cost, global, day-night, all-weather disaster warning and assistance. Evolving, advanced space technology with passive radio frequency reflectors in conjunction with an imaging synthetic aperture radar is employed to detect, identify, locate, and provide passive communication with earth users in distress. This concept evolved from a broad NASA research on new global search and rescue techniques. Appropriate airborne radar test results from this research are reviewed and related to potential disaster applications. The analysis indicates the approach has promise for disaster communications relative to floods, droughts, earthquakes, volcanic eruptions, and severe storms.

  18. Long life technology work at Rockwell International Space Division

    Huzel, D. K.

    1974-01-01

    This paper presents highlights of long-life technology oriented work performed at the Space Division of Rockwell International Corporation under contract to NASA. This effort included evaluation of Saturn V launch vehicle mechanical and electromechanical components for potential extended life capabilities, endurance tests, and accelerated aging experiments. A major aspect was evaluation of the components at the subassembly level (i.e., at the interface between moving surfaces) through in-depth wear analyses and assessments. Although some of this work is still in progress, preliminary conclusions are drawn and presented, together with the rationale for each. The paper concludes with a summary of the effort still remaining.

  19. Space Shuttle OMS engine valve technology. [Orbital Maneuvering System

    Wichmann, H.

    1974-01-01

    Valve technology program to determine shutoff valve concepts suitable for the Orbital Maneuvering System (OMS) engine of the Space Shuttle. The tradeoff studies selected the electric torque motor operated dual poppet and ball valves as the most desirable valve concepts for the OMS Engine Shutoff Valve. A prototype of one of these concepts was built and subjected to a design verification program. A number of unique features were designed to include the required contamination insensitivity, operating fluid compatibility, decontamination capability, minimum maintenance requirement and long service life capability.

  20. Emerging synergy between nanotechnology and implantable biosensors: a review.

    Vaddiraju, Santhisagar; Tomazos, Ioannis; Burgess, Diane J; Jain, Faquir C; Papadimitrakopoulos, Fotios

    2010-03-15

    The development of implantable biosensors for continuous monitoring of metabolites is an area of sustained scientific and technological interests. On the other hand, nanotechnology, a discipline which deals with the properties of materials at the nanoscale, is developing as a potent tool to enhance the performance of these biosensors. This article reviews the current state of implantable biosensors, highlighting the synergy between nanotechnology and sensor performance. Emphasis is placed on the electrochemical method of detection in light of its widespread usage and substantial nanotechnology based improvements in various aspects of electrochemical biosensor performance. Finally, issues regarding toxicity and biocompatibility of nanomaterials, along with future prospects for the application of nanotechnology in implantable biosensors, are discussed. (c) 2009 Elsevier B.V. All rights reserved.

  1. Political Show-Technology in the Post-Soviet Space

    O. E. Grishin

    2015-01-01

    Full Text Available In the modern political process of Russia actively used technology show. With their help, political actors can influence public opinion and shape the public interest in certain issues. In Russia, these technologies are relevant, and are especially well developed. The pressing of the problem is due to a new round of information war on the territory of Ukraine. Inclusion in the information space, and discuss the pressing issues of modern Ukraine by media people such as C. Shuster and V. Solovyov, suggests that the political show has entertainment figures, actuality, the ambiguity of the proposed conclusions. At the same time it becomes part of the information war and political reality of the normal state.

  2. Astronomy and Space Technologies, WILGA 2012; EuCARD Sessions

    Romaniuk, R S

    2012-01-01

    Wilga Sessions on HEP experiments, astroparticle physics and accelerator technology were organized under the umbrella of the EU FP7 Project EuCARD – European Coordination for Accelerator Research and Development. This paper is the first part (out of five) of the research survey of WILGA Symposium work, May 2012 Edition, concerned with photonics and electronics applications in astronomy and space technologies. It presents a digest of chosen technical work results shown by young researchers from different technical universities from this country during the Jubilee XXXth SPIE-IEEE Wilga 2012, May Edition, symposium on Photonics and Web Engineering. Topical tracks of the symposium embraced, among others, nanomaterials and nanotechnologies for photonics, sensory and nonlinear optical fibers, object oriented design of hardware, photonic metrology, optoelectronics and photonics applications, photonics-electronics co-design, optoelectronic and electronic systems for astronomy and high energy physics experiments, JE...

  3. Clinical Assessment Applications of Ambulatory Biosensors

    Haynes, Stephen N.; Yoshioka, Dawn T.

    2007-01-01

    Ambulatory biosensor assessment includes a diverse set of rapidly developing and increasingly technologically sophisticated strategies to acquire minimally disruptive measures of physiological and motor variables of persons in their natural environments. Numerous studies have measured cardiovascular variables, physical activity, and biochemicals…

  4. Advanced Exploration Technologies: Micro and Nano Technologies Enabling Space Missions in the 21st Century

    Krabach, Timothy

    1998-01-01

    Some of the many new and advanced exploration technologies which will enable space missions in the 21st century and specifically the Manned Mars Mission are explored in this presentation. Some of these are the system on a chip, the Computed-Tomography imaging Spectrometer, the digital camera on a chip, and other Micro Electro Mechanical Systems (MEMS) technology for space. Some of these MEMS are the silicon micromachined microgyroscope, a subliming solid micro-thruster, a micro-ion thruster, a silicon seismometer, a dewpoint microhygrometer, a micro laser doppler anemometer, and tunable diode laser (TDL) sensors. The advanced technology insertion is critical for NASA to decrease mass, volume, power and mission costs, and increase functionality, science potential and robustness.

  5. S-Layer Protein-Based Biosensors

    Bernhard Schuster

    2018-04-01

    Full Text Available The present paper highlights the application of bacterial surface (S- layer proteins as versatile components for the fabrication of biosensors. One technologically relevant feature of S-layer proteins is their ability to self-assemble on many surfaces and interfaces to form a crystalline two-dimensional (2D protein lattice. The S-layer lattice on the surface of a biosensor becomes part of the interface architecture linking the bioreceptor to the transducer interface, which may cause signal amplification. The S-layer lattice as ultrathin, highly porous structure with functional groups in a well-defined special distribution and orientation and an overall anti-fouling characteristics can significantly raise the limit in terms of variety and the ease of bioreceptor immobilization, compactness of bioreceptor molecule arrangement, sensitivity, specificity, and detection limit for many types of biosensors. The present paper discusses and summarizes examples for the successful implementation of S-layer lattices on biosensor surfaces in order to give a comprehensive overview on the application potential of these bioinspired S-layer protein-based biosensors.

  6. S-Layer Protein-Based Biosensors.

    Schuster, Bernhard

    2018-04-11

    The present paper highlights the application of bacterial surface (S-) layer proteins as versatile components for the fabrication of biosensors. One technologically relevant feature of S-layer proteins is their ability to self-assemble on many surfaces and interfaces to form a crystalline two-dimensional (2D) protein lattice. The S-layer lattice on the surface of a biosensor becomes part of the interface architecture linking the bioreceptor to the transducer interface, which may cause signal amplification. The S-layer lattice as ultrathin, highly porous structure with functional groups in a well-defined special distribution and orientation and an overall anti-fouling characteristics can significantly raise the limit in terms of variety and the ease of bioreceptor immobilization, compactness of bioreceptor molecule arrangement, sensitivity, specificity, and detection limit for many types of biosensors. The present paper discusses and summarizes examples for the successful implementation of S-layer lattices on biosensor surfaces in order to give a comprehensive overview on the application potential of these bioinspired S-layer protein-based biosensors.

  7. In vitro evaluation of fluorescence glucose biosensor response.

    Aloraefy, Mamdouh; Pfefer, T Joshua; Ramella-Roman, Jessica C; Sapsford, Kim E

    2014-07-08

    Rapid, accurate, and minimally-invasive glucose biosensors based on Förster Resonance Energy Transfer (FRET) for glucose measurement have the potential to enhance diabetes control. However, a standard set of in vitro approaches for evaluating optical glucose biosensor response under controlled conditions would facilitate technological innovation and clinical translation. Towards this end, we have identified key characteristics and response test methods, fabricated FRET-based glucose biosensors, and characterized biosensor performance using these test methods. The biosensors were based on competitive binding between dextran and glucose to concanavalin A and incorporated long-wavelength fluorescence dye pairs. Testing characteristics included spectral response, linearity, sensitivity, limit of detection, kinetic response, reversibility, stability, precision, and accuracy. The biosensor demonstrated a fluorescence change of 45% in the presence of 400 mg/dL glucose, a mean absolute relative difference of less than 11%, a limit of detection of 25 mg/dL, a response time of 15 min, and a decay in fluorescence intensity of 72% over 30 days. The battery of tests presented here for objective, quantitative in vitro evaluation of FRET glucose biosensors performance have the potential to form the basis of future consensus standards. By implementing these test methods for a long-visible-wavelength biosensor, we were able to demonstrate strengths and weaknesses with a new level of thoroughness and rigor.

  8. In Vitro Evaluation of Fluorescence Glucose Biosensor Response

    Mamdouh Aloraefy

    2014-07-01

    Full Text Available Rapid, accurate, and minimally-invasive glucose biosensors based on Förster Resonance Energy Transfer (FRET for glucose measurement have the potential to enhance diabetes control. However, a standard set of in vitro approaches for evaluating optical glucose biosensor response under controlled conditions would facilitate technological innovation and clinical translation. Towards this end, we have identified key characteristics and response test methods, fabricated FRET-based glucose biosensors, and characterized biosensor performance using these test methods. The biosensors were based on competitive binding between dextran and glucose to concanavalin A and incorporated long-wavelength fluorescence dye pairs. Testing characteristics included spectral response, linearity, sensitivity, limit of detection, kinetic response, reversibility, stability, precision, and accuracy. The biosensor demonstrated a fluorescence change of 45% in the presence of 400 mg/dL glucose, a mean absolute relative difference of less than 11%, a limit of detection of 25 mg/dL, a response time of 15 min, and a decay in fluorescence intensity of 72% over 30 days. The battery of tests presented here for objective, quantitative in vitro evaluation of FRET glucose biosensors performance have the potential to form the basis of future consensus standards. By implementing these test methods for a long-visible-wavelength biosensor, we were able to demonstrate strengths and weaknesses with a new level of thoroughness and rigor.

  9. BIOSENSORS FOR ENVIRONMENTAL APPLICATIONS

    A review, with 19 references, is given on challenges and possible opportunities for the development of biosensors for environmental monitoring applications. The high cost and slow turnaround times typically associated with the measurement of regulated pollutants clearly indicates...

  10. Nanochannels Photoelectrochemical Biosensor.

    Zhang, Nan; Ruan, Yi-Fan; Zhang, Li-Bin; Zhao, Wei-Wei; Xu, Jing-Juan; Chen, Hong-Yuan

    2018-02-06

    Nanochannels have brought new opportunities for biosensor development. Herein, we present the novel concept of a nanochannels photoelectrochemical (PEC) biosensor based on the integration of a unique Cu x O-nanopyramid-islands (NPIs) photocathode, an anodic aluminum oxide (AAO) membrane, and alkaline phosphatase (ALP) catalytic chemistry. The Cu x O-NPIs photocathode possesses good performance, and further assembly with AAO yields a designed architecture composed of vertically aligned, highly ordered nanoarrays on top of the Cu x O-NPIs film. After biocatalytic precipitation (BCP) was stimulated within the channels, the biosensor was used for the successful detection of ALP activity. This study has not only provided a novel paradigm for an unconventional nanochannels PEC biosensor, which can be used for general bioanalytical purposes, but also indicated that the new concept of nanochannel-semiconductor heterostructures is a step toward innovative biomedical applications.

  11. Integration of advanced teleoperation technologies for control of space robots

    Stagnaro, Michael J.

    1993-01-01

    Teleoperated robots require one or more humans to control actuators, mechanisms, and other robot equipment given feedback from onboard sensors. To accomplish this task, the human or humans require some form of control station. Desirable features of such a control station include operation by a single human, comfort, and natural human interfaces (visual, audio, motion, tactile, etc.). These interfaces should work to maximize performance of the human/robot system by streamlining the link between human brain and robot equipment. This paper describes development of a control station testbed with the characteristics described above. Initially, this testbed will be used to control two teleoperated robots. Features of the robots include anthropomorphic mechanisms, slaving to the testbed, and delivery of sensory feedback to the testbed. The testbed will make use of technologies such as helmet mounted displays, voice recognition, and exoskeleton masters. It will allow tor integration and testing of emerging telepresence technologies along with techniques for coping with control link time delays. Systems developed from this testbed could be applied to ground control of space based robots. During man-tended operations, the Space Station Freedom may benefit from ground control of IVA or EVA robots with science or maintenance tasks. Planetary exploration may also find advanced teleoperation systems to be very useful.

  12. Scientific applications of frequency-stabilized laser technology in space

    Schumaker, Bonny L.

    1990-01-01

    A synoptic investigation of the uses of frequency-stabilized lasers for scientific applications in space is presented. It begins by summarizing properties of lasers, characterizing their frequency stability, and describing limitations and techniques to achieve certain levels of frequency stability. Limits to precision set by laser frequency stability for various kinds of measurements are investigated and compared with other sources of error. These other sources include photon-counting statistics, scattered laser light, fluctuations in laser power, and intensity distribution across the beam, propagation effects, mechanical and thermal noise, and radiation pressure. Methods are explored to improve the sensitivity of laser-based interferometric and range-rate measurements. Several specific types of science experiments that rely on highly precise measurements made with lasers are analyzed, and anticipated errors and overall performance are discussed. Qualitative descriptions are given of a number of other possible science applications involving frequency-stabilized lasers and related laser technology in space. These applications will warrant more careful analysis as technology develops.

  13. Triggered optical biosensor

    Song, Xuedong; Swanson, Basil I.

    2001-10-02

    An optical biosensor is provided for the detection of a multivalent target biomolecule, the biosensor including a substrate having a bilayer membrane thereon, a recognition molecule situated at the surface, the recognition molecule capable of binding with the multivalent target biomolecule, the recognition molecule further characterized as including a fluorescence label thereon and as being movable at the surface and a device for measuring a fluorescence change in response to binding between the recognition molecule and the multivalent target biomolecule.

  14. The Science and Technology of Future Space Missions

    Bonati, A.; Fusi, R.; Longoni, F.

    1999-12-01

    The future space missions span over a wide range of scientific objectives. After different successful scientific missions, other international cornerstone experiments are planned to study of the evolution of the universe and of the primordial stellar systems, and our solar system. Space missions for the survey of the microwave cosmic background radiation, deep-field search in the near and mid-infrared region and planetary exploration will be carried out. Several fields are open for research and development in the space business. Three major categories can be found: detector technology in different areas, electronics, and software. At LABEN, a Finmeccanica Company, we are focusing the technologies to respond to this challenging scientific demands. Particle trackers based on silicon micro-strips supported by lightweight structures (CFRP) are studied. In the X-ray field, CCD's are investigated with pixels of very small size so as to increase the spatial resolution of the focal plane detectors. High-efficiency and higly miniaturized high-voltage power supplies are developed for detectors with an increasingly large number of phototubes. Material research is underway to study material properties at extreme temperatures. Low-temperature mechanical structures are designed for cryogenic ( 20 K) detectors in order to maintain the high precision in pointing the instrument. Miniaturization of front end electronics with low power consumption and high number of signal processing channels is investigated; silicon-based microchips (ASIC's) are designed and developed using state-of-the-art technology. Miniaturized instruments to investigate the planets surface using X-Ray and Gamma-Ray scattering techniques are developed. The data obtained from the detectors have to be processed, compressed, formatted and stored before their transmission to ground. These tasks open up additional strategic areas of development such as microprocessor-based electronics for high-speed and parallel data

  15. Logistics Reduction and Repurposing Technology for Long Duration Space Missions

    Broyan, James L.; Chu, Andrew; Ewert, Michael K.

    2014-01-01

    One of NASA's Advanced Exploration Systems (AES) projects is the Logistics Reduction and Repurposing (LRR) project, which has the goal of reducing logistics resupply items through direct and indirect means. Various technologies under development in the project will reduce the launch mass of consumables and their packaging, enable reuse and repurposing of items and make logistics tracking more efficient. Repurposing also reduces the trash burden onboard spacecraft and indirectly reduces launch mass by replacing some items on the manifest. Examples include reuse of trash as radiation shielding or propellant. This paper provides the status of the LRR technologies in their third year of development under AES. Advanced clothing systems (ACS) are being developed to enable clothing to be worn longer, directly reducing launch mass. ACS has completed a ground exercise clothing study in preparation for an International Space Station (ISS) technology demonstration in 2014. Development of launch packaging containers and other items that can be repurposed on-orbit as part of habitation outfitting has resulted in a logistics-to-living (L2L) concept. L2L has fabricated and evaluated several multi-purpose cargo transfer bags (MCTBs) for potential reuse on orbit. Autonomous logistics management (ALM) is using radio frequency identification (RFID) to track items and thus reduce crew requirements for logistics functions. An RFID dense reader prototype is under construction and plans for integrated testing are being made. Development of a heat melt compactor (HMC) second generation unit for processing trash into compact and stable tiles is nearing completion. The HMC prototype compaction chamber has been completed and system development testing is underway. Research has been conducted on the conversion of trash-to-gas (TtG) for high levels of volume reduction and for use in propulsion systems. A steam reformation system was selected for further system definition of the TtG technology

  16. New Cryogenic Optical Test Capability at Marshall Space Flight Center's Space Optics Manufacturing Technology Center

    Kegley, Jeff; Burdine, Robert V. (Technical Monitor)

    2002-01-01

    A new cryogenic optical testing capability exists at Marshall Space Flight Center's Space Optics Manufacturing Technology Center (SOMTC). SOMTC has been performing optical wavefront testing at cryogenic temperatures since 1999 in the X-ray Cryogenic Test Facility's (XRCF's) large vacuum chamber. Recently the cryogenic optical testing capability has been extended to a smaller vacuum chamber. This smaller horizontal cylindrical vacuum chamber has been outfitted with a helium-cooled liner that can be connected to the facility's helium refrigeration system bringing the existing kilowatt of refrigeration capacity to bear on a 1 meter diameter x 2 meter long test envelope. Cryogenic environments to less than 20 Kelvin are now possible in only a few hours. SOMTC's existing instruments (the Instantaneous Phase-shifting Interferometer (IPI) from ADE Phase-Shift Technologies and the PhaseCam from 4D Vision Technologies) view the optic under test through a 150 mm clear aperture BK-7 window. Since activation and chamber characterization tests in September 2001, the new chamber has been used to perform a cryogenic (less than 30 Kelvin) optical test of a 22.5 cm diameter x 127 cm radius of curvature Si02 mirror, a cryogenic survival (less than 30 Kelvin) test of an adhesive, and a cryogenic cycle (less than 20 Kelvin) test of a ULE mirror. A vibration survey has also been performed on the test chamber. Chamber specifications and performance data, vibration environment data, and limited test results will be presented.

  17. NASA Johnson Space Center SBIR STTR Program Technology Innovations

    Krishen, Kumar

    2007-01-01

    The Small Business Innovation Research (SBIR) Program increases opportunities for small businesses to participate in research and development (R&D), increases employment, and improves U.S. competitiveness. Specifically the program stimulates U.S. technological innovation by using small businesses to meet federal R&D needs, increasing private-sector commercialization of innovations derived from federal R&D, and fostering and encouraging the participation of socially disadvantaged businesses. In 2000, the Small Business Technology Transfer (STTR) Program extended and strengthened the SBIR Program, increasing its emphasis on pursuing commercial applications by awarding contracts to small business concerns for cooperative R&D with a nonprofit research institution. Modeled after the SBIR Program, STTR is nevertheless a separately funded activity. Technologies that have resulted from the Johnson Space Center SBIR STTR Program include: a device for regenerating iodinated resin beds; laser-assisted in-situ keratomileusis or LASIK; a miniature physiological monitoring device capable of collecting and analyzing a multitude of real-time signals to transmit medical data from remote locations to medical centers for diagnosis and intervention; a new thermal management system for fibers and fabrics giving rise to new line of garments and thermal-enhancing environments; and a highly electropositive material that attracts and retains electronegative particles in water.

  18. Augmenting Space Technology Program Management with Secure Cloud & Mobile Services

    Hodson, Robert F.; Munk, Christopher; Helble, Adelle; Press, Martin T.; George, Cory; Johnson, David

    2017-01-01

    The National Aeronautics and Space Administration (NASA) Game Changing Development (GCD) program manages technology projects across all NASA centers and reports to NASA headquarters regularly on progress. Program stakeholders expect an up-to-date, accurate status and often have questions about the program's portfolio that requires a timely response. Historically, reporting, data collection, and analysis were done with manual processes that were inefficient and prone to error. To address these issues, GCD set out to develop a new business automation solution. In doing this, the program wanted to leverage the latest information technology platforms and decided to utilize traditional systems along with new cloud-based web services and gaming technology for a novel and interactive user environment. The team also set out to develop a mobile solution for anytime information access. This paper discusses a solution to these challenging goals and how the GCD team succeeded in developing and deploying such a system. The architecture and approach taken has proven to be effective and robust and can serve as a model for others looking to develop secure interactive mobile business solutions for government or enterprise business automation.

  19. Sense and sensitivity in bioprocessing-detecting cellular metabolites with biosensors.

    Dekker, Linda; Polizzi, Karen M

    2017-10-01

    Biosensors use biological elements to detect or quantify an analyte of interest. In bioprocessing, biosensors are employed to monitor key metabolites. There are two main types: fully biological systems or biological recognition coupled with physical/chemical detection. New developments in chemical biosensors include multiplexed detection using microfluidics. Synthetic biology can be used to engineer new biological biosensors with improved characteristics. Although there have been few biosensors developed for bioprocessing thus far, emerging trends can be applied in the future. A range of new platform technologies will enable rapid engineering of new biosensors based on transcriptional activation, riboswitches, and Förster Resonance Energy Transfer. However, translation to industry remains a challenge and more research into the robustness biosensors at scale is needed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. HI-STAR. Health Improvements Through Space Technologies and Resources: Final Report

    Finarelli, Margaret G.

    2002-01-01

    The purpose of this document is to describe a global strategy to integrate the use of space technology in the fight against malaria. Given the well-documented relationship between the vector and its environment, and the ability of existing space technologies to monitor environmental factors, malaria is a strong candidate for the application of space technology. The concept of a malaria early warning system has been proposed in the past' and pilot studies have been conducted. The HI-STAR project (Health Improvement through Space Technologies and Resources) seeks to build on this concept and enhance the space elements of the suggested framework. As such, the mission statement for this International Space University design project has been defined as follows: "Our mission is to develop and promote a global strategy to help combat malaria using space technology". A general overview of malaria, aspects of how space technology can be useful, and an outline of the HI-STAR strategy is presented.

  1. A Mobile Communications Space Link Between the Space Shuttle Orbiter and the Advanced Communications Technology Satellite

    Fink, Patrick; Arndt, G. D.; Bondyopadhyay, P.; Shaw, Roland

    1994-01-01

    A communications experiment is described as a link between the Space Shuttle Orbiter (SSO) and the Advanced Communications Technology Satellite (ACTS). Breadboarding for this experiment has led to two items with potential for commercial application: a 1-Watt Ka-band amplifier and a Ka-band, circularly polarized microstrip antenna. Results of the hybrid Ka-band amplifier show gain at 30 dB and a saturated output power of 28.5 dBm. A second version comprised of MMIC amplifiers is discussed. Test results of the microstrip antenna subarray show a gain of approximately 13 dB and excellent circular polarization.

  2. Future of biosensors: a personal view.

    Scheller, Frieder W; Yarman, Aysu; Bachmann, Till; Hirsch, Thomas; Kubick, Stefan; Renneberg, Reinhard; Schumacher, Soeren; Wollenberger, Ulla; Teller, Carsten; Bier, Frank F

    2014-01-01

    Biosensors representing the technological counterpart of living senses have found routine application in amperometric enzyme electrodes for decentralized blood glucose measurement, interaction analysis by surface plasmon resonance in drug development, and to some extent DNA chips for expression analysis and enzyme polymorphisms. These technologies have already reached a highly advanced level and need minor improvement at most. The dream of the "100-dollar" personal genome may come true in the next few years provided that the technological hurdles of nanopore technology or of polymerase-based single molecule sequencing can be overcome. Tailor-made recognition elements for biosensors including membrane-bound enzymes and receptors will be prepared by cell-free protein synthesis. As alternatives for biological recognition elements, molecularly imprinted polymers (MIPs) have been created. They have the potential to substitute antibodies in biosensors and biochips for the measurement of low-molecular-weight substances, proteins, viruses, and living cells. They are more stable than proteins and can be produced in large amounts by chemical synthesis. Integration of nanomaterials, especially of graphene, could lead to new miniaturized biosensors with high sensitivity and ultrafast response. In the future individual therapy will include genetic profiling of isoenzymes and polymorphic forms of drug-metabolizing enzymes especially of the cytochrome P450 family. For defining the pharmacokinetics including the clearance of a given genotype enzyme electrodes will be a useful tool. For decentralized online patient control or the integration into everyday "consumables" such as drinking water, foods, hygienic articles, clothing, or for control of air conditioners in buildings and cars and swimming pools, a new generation of "autonomous" biosensors will emerge.

  3. Logistics Reduction and Repurposing Technology for Long Duration Space Missions

    Broyan, James Lee, Jr.; Chu, Andrew; Ewert, Michael K.

    2014-01-01

    One of NASA's Advanced Exploration Systems (AES) projects is the Logistics Reduction and Repurposing (LRR) project, which has the goal of reducing logistics resupply items through direct and indirect means. Various technologies under development in the project will reduce the launch mass of consumables and their packaging, enable reuse and repurposing of items, and make logistics tracking more efficient. Repurposing also reduces the trash burden onboard spacecraft and indirectly reduces launch mass by one manifest item having two purposes rather than two manifest items each having only one purpose. This paper provides the status of each of the LRR technologies in their third year of development under AES. Advanced clothing systems (ACSs) are being developed to enable clothing to be worn longer, directly reducing launch mass. ACS has completed a ground exercise clothing study in preparation for an International Space Station technology demonstration in 2014. Development of launch packaging containers and other items that can be repurposed on-orbit as part of habitation outfitting has resulted in a logistics-to-living (L2L) concept. L2L has fabricated and evaluated several multi-purpose cargo transfer bags for potential reuse on-orbit. Autonomous logistics management is using radio frequency identification (RFID) to track items and thus reduce crew time for logistics functions. An RFID dense reader prototype is under construction and plans for integrated testing are being made. A heat melt compactor (HMC) second generation unit for processing trash into compact and stable tiles is nearing completion. The HMC prototype compaction chamber has been completed and system development testing is under way. Research has been conducted on the conversion of trash-to-gas (TtG) for high levels of volume reduction and for use in propulsion systems. A steam reformation system was selected for further system definition of the TtG technology.

  4. Super Global Projects and Environmentally Friendly Technologies Used in Space Exploration: Realities and Prospects of the Space Age

    Sergey Krichevsky

    2018-02-01

    Full Text Available The 60th anniversary of the Space Age is an important intermediate finishing point on the way of a man and the whole humanity to space. Along with the outstanding achievements, there are a number of challenges and contradictions in space exploration due to the aggravation of the global crisis on Earth, low efficiency and the backlog of space research in the transition to a new technology based reality and clean technologies. Both the international astronautics and the space exploration area nowadays face difficulties in choosing a new paradigm and a development strategy that is becoming even more complicated due to the current unstable and turbulent situation on Earth. The article reveals the optimistic scenario of further space exploration, as well as the methodological and practical aspects of new projects and technologies. The periodization of the Space Age history has been conducted. It has been also proposed a new classification of the “space” phenomenon due to concretizing the concept of “global” in the form of a three-scale structure encompassing the following levels: 1 planetary global; 2 super global; 3 universally global. The notion of “super global space exploration project” has been introduced. The concept of further space exploration is proposed, which includes four interrelated super global projects:1 Earth Protection System from Asteroid and Comet Threat; 2 Moon Exploration; 3 Mars Exploration; 4 Cosmic Humanity. Since the humanity is embarking on the practical implementation of these super global projects, it is urgent to make a transition towards a new technology based order, as well as up-to-date technologies. A couple of ecological projects and space exploration technologies of the 20th and 21st centuries have been exemplified and analyzed. It has been also worked out the list of new environmentally friendly space technologies and projects. The research makes an emphasis upon a great potential of clean and green

  5. Molecular Approaches to Optical Biosensors

    Fierke, Carol

    1998-01-01

    The goal of this proposal was to develop methodologies for the optimization of field-deployable optical biosensors, in general, and, in particular, to optimize a carbonic anhydrase-based fiber optic zinc biosensor...

  6. Microorganisms applying for artificial soil regeneration technology in space greenhouses

    Krivobok, A. S.

    2012-04-01

    The space greenhouse and technology for growing plants are being designed in frame of bio-technical life support systems development. During long-term space missions such greenhouse could provide the crew with vitamins and rough plant fiber. One of the important elements of the plant cultivation technology in the absence of earth gravity is organization and support the optimum root area. The capillary-porous substrate composed of anionites (FIBAN -1) and cationites (FIBAN -22-1) synthetic salt-saturated fibers is developed for plant cultivation in space and named "BIONA-V3". The BIONA main features are high productivity and usability. But the pointed features are not constant: the substrate productivity will be decreasing gradually from vegetation to vegetation course of plant residues and root secretions accumulation. Also, the basic hydro-physical characteristic of root zone will be shifted. Furthermore, saprotrophic microflora will develop and lead to increasing the level of microbial contamination of whole inhabit isolated module. Due to these changes the substrate useful life is limited and store mass is increased in long-term missions. For overhaul-period renewal it' necessary to remove the roots residues and other organic accumulation providing safety of the substrate capillary-porous structure. The basic components of 24-days old plant roots (Brassica chinensis, L) are cellulose (35 %) hemicellulose (11 %) and lignin (10 %). We see that one of the possible ways for roots residues removal from fibrous BIONA is microorganisms applying with strong cellulolytic and ligninolytic activities. The fungi Trichoderma sp., cellulolytic bacteria associations, and some genus of anaerobic thermophilic cellulolitic bacteria have been used for roots residues biodegradation. In case of applying cellulolytic fungi Trichoderma sp. considerable decrease of microcrystalline cellulose has been noted in both liquid and solid state fermentation. Cellulolytic fungi weight has been

  7. Advancements in water vapor electrolysis technology. [for Space Station ECLSS

    Chullen, Cinda; Heppner, Dennis B.; Sudar, Martin

    1988-01-01

    The paper describes a technology development program whose goal is to develop water vapor electrolysis (WVE) hardware that can be used selectively as localized topping capability in areas of high metabolic activity without oversizing the central air revitalization system on long-duration manned space missions. The WVE will be used primarily to generate O2 for the crew cabin but also to provide partial humidity control by removing water vapor from the cabin atmosphere. The electrochemically based WVE interfaces with cabin air which is controlled in the following ranges: dry bulb temperature of 292 to 300 K; dew point temperature of 278 to 289 K; relative humidity of 25 to 75 percent; and pressure of 101 + or - 1.4 kPa. Design requirements, construction details, and results for both single-cell and multicell module testing are presented, and the preliminary sizing of a multiperson subsystem is discussed.

  8. Reduction Potato s hydric soil erosion using space technology

    Guyot, E.; Rios, V.; Zelaya, D.; Rios, E.; Lepen, F.; Padilla, P.; Soria, F.

    The potato's crop has an econ omic importance in Tucuman's agricultural PBI (Gross Product Income) because its rank is fourth(4°). Production's potato area is a breakable agro system; its geographic location is in Pedemonte's agro-ecological region so is essential to handle hydric erosion. Therefore, the aim of this work is improve crop's potato irrigation management through satellite information merge with farm's practices. The space technology consented to obtain Digital Model Soil using both unique differential and dual frequency GPS signals and total station. The irrigation practices were carried out due to irrigation management (FAO) and satellite imagine software (ENVI). Preliminary results of this experience allowed to follow the crop's growing through multitemporal study; reprogramming farm's irrigation practices intended for manage reduction hydric erosion and heighten economically its productivity for the next period

  9. Evasive Maneuvers in Space Debris Environment and Technological Parameters

    Antônio D. C. Jesus

    2012-01-01

    Full Text Available We present a study of collisional dynamics between space debris and an operational vehicle in LEO. We adopted an approach based on the relative dynamics between the objects on a collisional course and with a short warning time and established a semianalytical solution for the final trajectories of these objects. Our results show that there are angular ranges in 3D, in addition to the initial conditions, that favor the collisions. These results allowed the investigation of a range of technological parameters for the spacecraft (e.g., fuel reserve that allow a safe evasive maneuver (e.g., time available for the maneuver. The numerical model was tested for different values of the impact velocity and relative distance between the approaching objects.

  10. The transfer of dual-use outer space technologies: confrontation or co-operation ?

    Gasparini Alves, Péricles; Gasteyger, Curt

    2005-01-01

    The right of any State to develop outer space technologies is, in principle, unquestionable. In practice, problems arise when technology development approaches the very fine line between civil and military application, largely because most the technologies can be used for dual military and civil purposes. This dichotomy has raised a series of political, military, and other concerns which affect the transfer of outer space technologies, and particularly between established and emerging space-c...

  11. Advancing automation and robotics technology for the Space Station and for the US economy, volume 2

    1985-01-01

    In response to Public Law 98-371, dated July 18, 1984, the NASA Advanced Technology Advisory Committee has studied automation and robotics for use in the Space Station. The Technical Report, Volume 2, provides background information on automation and robotics technologies and their potential and documents: the relevant aspects of Space Station design; representative examples of automation and robotics; applications; the state of the technology and advances needed; and considerations for technology transfer to U.S. industry and for space commercialization.

  12. Technology for Space Station Evolution. Volume 3: EVA/Manned Systems/Fluid Management System

    1990-01-01

    NASA's Office of Aeronautics and Space Technology (OAST) conducted a workshop on technology for space station evolution 16-19 Jan. 1990 in Dallas, Texas. The purpose of this workshop was to collect and clarify Space Station Freedom technology requirements for evolution and to describe technologies that can potentially fill those requirements. These proceedings are organized into an Executive Summary and Overview and five volumes containing the Technology Discipline Presentations. Volume 3 consists of the technology discipline sections for Extravehicular Activity/Manned Systems and the Fluid Management System. For each technology discipline, there is a Level 3 subsystem description, along with the papers.

  13. A new space technology for ocean observation: the SMOS mission

    Jordi Font

    2012-09-01

    Full Text Available Capability for sea surface salinity observation was an important gap in ocean remote sensing in the last few decades of the 20th century. New technological developments during the 1990s at the European Space Agency led to the proposal of SMOS (Soil Moisture and Ocean Salinity, an Earth explorer opportunity mission based on the use of a microwave interferometric radiometer, MIRAS (Microwave Imaging Radiometer with Aperture Synthesis. SMOS, the first satellite ever addressing the observation of ocean salinity from space, was successfully launched in November 2009. The determination of salinity from the MIRAS radiometric measurements at 1.4 GHz is a complex procedure that requires high performance from the instrument and accurate modelling of several physical processes that impact on the microwave emission of the ocean’s surface. This paper introduces SMOS in the ocean remote sensing context, and summarizes the MIRAS principles of operation and the SMOS salinity retrieval approach. It describes the Spanish SMOS high-level data processing centre (CP34 and the SMOS Barcelona Expert Centre on Radiometric Calibration and Ocean Salinity (SMOS-BEC, and presents a preliminary validation of global sea surface salinity maps operationally produced by CP34.

  14. Immersive Earth: Teaching Earth and Space with inexpensive immersive technology

    Reiff, P. H.; Sumners, C.; Law, C. C.; Handron, K.

    2003-12-01

    In 1995 we pioneered "Space Update", the Digital Library for the rest of us", software that was so simple that a child could use it without a keyboard and yet would allow one-click updating of the daily earth and space science images without the dangers of having an open web browser on display. Thanks to NASA support, it allowed museums and schools to have a powerful exhibit for a tiny price. Over 40,000 disks in our series have been distributed so far to educators and the public. In 2003, with our partners we are again revolutionizing educational technology with a low-cost hardware and software solution to creating and displaying immersive content. Recently selected for funding as part of the REASoN competition, Immersive Earth is a partnership of scientists, museums, educators, and content providers. The hardware consists of a modest projector with a special fisheye lens to be used in an inflatable dome which many schools already have. This, coupled with a modest personal computer, can now easily project images and movies of earth and space, allows training students in 3-D content at a tiny fraction of the cost of a cave or fullscale dome theater. Another low-cost solution is the "Imove" system, where spherical movies can play on a personal computer, with the user changing the viewing direction with a joystick. We were the first to create immersive earth science shows, remain the leader in creating educational content that people want to see. We encourage people with "allsky" images or movies to bring it and see what it looks like inside a dome! Your content could be in our next show!

  15. Space-based Networking Technology Developments in the Interplanetary Network Directorate Information Technology Program

    Clare, Loren; Clement, B.; Gao, J.; Hutcherson, J.; Jennings, E.

    2006-01-01

    Described recent development of communications protocols, services, and associated tools targeted to reduce risk, reduce cost and increase efficiency of IND infrastructure and supported mission operations. Space-based networking technologies developed were: a) Provide differentiated quality of service (QoS) that will give precedence to traffic that users have selected as having the greatest importance and/or time-criticality; b) Improve the total value of information to users through the use of QoS prioritization techniques; c) Increase operational flexibility and improve command-response turnaround; d) Enable new class of networked and collaborative science missions; e) Simplify applications interfaces to communications services; and f) Reduce risk and cost from a common object model and automated scheduling and communications protocols. Technologies are described in three general areas: communications scheduling, middleware, and protocols. Additionally developed simulation environment, which provides comprehensive, quantitative understanding of the technologies performance within overall, evolving architecture, as well as ability to refine & optimize specific components.

  16. Space Technology Mission Directorate Game Changing Development Program FY2015 Annual Program Review: Advanced Manufacturing Technology

    Vickers, John; Fikes, John

    2015-01-01

    The Advance Manufacturing Technology (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of the Initiative is the Advanced Manufacturing National Program Office (AMNPO), which includes participation from all federal agencies involved in U.S. manufacturing. In support of the AMNPO the AMT Project supports building and Growing the National Network for Manufacturing Innovation through a public-private partnership designed to help the industrial community accelerate manufacturing innovation. Integration with other projects/programs and partnerships: STMD (Space Technology Mission Directorate), HEOMD, other Centers; Industry, Academia; OGA's (e.g., DOD, DOE, DOC, USDA, NASA, NSF); Office of Science and Technology Policy, NIST Advanced Manufacturing Program Office; Generate insight within NASA and cross-agency for technology development priorities and investments. Technology Infusion Plan: PC; Potential customer infusion (TDM, HEOMD, SMD, OGA, Industry); Leverage; Collaborate with other Agencies, Industry and Academia; NASA roadmap. Initiatives include: Advanced Near Net Shape Technology Integrally Stiffened Cylinder Process Development (launch vehicles, sounding rockets); Materials Genome; Low Cost Upper Stage-Class Propulsion; Additive Construction with Mobile Emplacement (ACME); National Center for Advanced Manufacturing.

  17. Photoelectrochemical enzymatic biosensors.

    Zhao, Wei-Wei; Xu, Jing-Juan; Chen, Hong-Yuan

    2017-06-15

    Enzymatic biosensors have been valuable bioanalytical devices for analysis of diverse targets in disease diagnosis, biological and biomedical research, etc. Photoelectrochemical (PEC) bioanalysis is a recently emerged method that promptly becoming a subject of new research interests due to its attractive potential for future bioanalysis with high sensitivity and specificity. PEC enzymatic biosensors integrate the inherent sensitivities of PEC bioanalysis and the selectivity of enzymes and thus share their both advantages. Currently, PEC enzymatic biosensors have become a hot topic of significant research and the recent impetus has grown rapidly as demonstrated by increased research papers. Given the pace of advances in this area, this review will make a thorough discussion and survey on the fundamentals, sensing strategies, applications and the state of the art in PEC enzymatic biosensors, followed by future prospects based on our own opinions. We hope this work could provide an accessible introduction to PEC enzymatic biosensors for any scientist. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Space biology research development

    Bonting, Sjoerd L.

    1993-01-01

    The purpose of the Search for Extraterrestrial Intelligence (SETI) Institute is to conduct and promote research related activities regarding the search for extraterrestrial life, particularly intelligent life. Such research encompasses the broad discipline of 'Life in the Universe', including all scientific and technological aspects of astronomy and the planetary sciences, chemical evolution, the origin of life, biological evolution, and cultural evolution. The primary purpose was to provide funding for the Principal Investigator to collaborate with the personnel of the SETI Institute and the NASA-Ames Research center in order to plan and develop space biology research on and in connection with Space Station Freedom; to promote cooperation with the international partners in the space station; to conduct a study on the use of biosensors in space biology research and life support system operation; and to promote space biology research through the initiation of an annual publication 'Advances in Space Biology and Medicine'.

  19. NASA space station automation: AI-based technology review. Executive summary

    Firschein, O.; Georgeff, M. P.; Park, W.; Cheeseman, P. C.; Goldberg, J.; Neumann, P.; Kautz, W. H.; Levitt, K. N.; Rom, R. J.; Poggio, A. A.

    1985-01-01

    Research and Development projects in automation technology for the Space Station are described. Artificial Intelligence (AI) based technologies are planned to enhance crew safety through reduced need for EVA, increase crew productivity through the reduction of routine operations, increase space station autonomy, and augment space station capability through the use of teleoperation and robotics.

  20. Matrix-insensitive protein assays push the limits of biosensors in medicine

    Gaster, Richard S; Hall, Drew A; Nielsen, Carsten Haagen

    2009-01-01

    Advances in biosensor technologies for in vitro diagnostics have the potential to transform the practice of medicine. Despite considerable work in the biosensor field, there is still no general sensing platform that can be ubiquitously applied to detect the constellation of biomolecules in diverse...... magnetic nanosensor technology can be directly applied to a variety of settings such as molecular biology, clinical diagnostics and biodefense....

  1. Modeling microelectrode biosensors: free-flow calibration can substantially underestimate tissue concentrations.

    Newton, Adam J H; Wall, Mark J; Richardson, Magnus J E

    2017-03-01

    Microelectrode amperometric biosensors are widely used to measure concentrations of analytes in solution and tissue including acetylcholine, adenosine, glucose, and glutamate. A great deal of experimental and modeling effort has been directed at quantifying the response of the biosensors themselves; however, the influence that the macroscopic tissue environment has on biosensor response has not been subjected to the same level of scrutiny. Here we identify an important issue in the way microelectrode biosensors are calibrated that is likely to have led to underestimations of analyte tissue concentrations. Concentration in tissue is typically determined by comparing the biosensor signal to that measured in free-flow calibration conditions. In a free-flow environment the concentration of the analyte at the outer surface of the biosensor can be considered constant. However, in tissue the analyte reaches the biosensor surface by diffusion through the extracellular space. Because the enzymes in the biosensor break down the analyte, a density gradient is set up resulting in a significantly lower concentration of analyte near the biosensor surface. This effect is compounded by the diminished volume fraction (porosity) and reduction in the diffusion coefficient due to obstructions (tortuosity) in tissue. We demonstrate this effect through modeling and experimentally verify our predictions in diffusive environments. NEW & NOTEWORTHY Microelectrode biosensors are typically calibrated in a free-flow environment where the concentrations at the biosensor surface are constant. However, when in tissue, the analyte reaches the biosensor via diffusion and so analyte breakdown by the biosensor results in a concentration gradient and consequently a lower concentration around the biosensor. This effect means that naive free-flow calibration will underestimate tissue concentration. We develop mathematical models to better quantify the discrepancy between the calibration and tissue

  2. Last Advances in Silicon-Based Optical Biosensors.

    Fernández Gavela, Adrián; Grajales García, Daniel; Ramirez, Jhonattan C; Lechuga, Laura M

    2016-02-24

    We review the most important achievements published in the last five years in the field of silicon-based optical biosensors. We focus specially on label-free optical biosensors and their implementation into lab-on-a-chip platforms, with an emphasis on developments demonstrating the capability of the devices for real bioanalytical applications. We report on novel transducers and materials, improvements of existing transducers, new and improved biofunctionalization procedures as well as the prospects for near future commercialization of these technologies.

  3. Biosensors in forensic sciences

    Frederickx, C.

    2011-01-01

    Full Text Available A biosensor is a device that uses biological materials to detect and monitor the presence of specific chemicals in an area. Traditional methods of volatile detection used by law enforcement agencies and rescue teams typically consist of reliance on canine olfaction. This concept of using dogs to detect specific substances is quite old. However, dogs have some limitations such as cost of training and time of conditioning. Thus, the possibility of using other organisms as biosensors including rats, dolphins, honeybees, and parasitic wasps for detecting explosives, narcotics and cadavers has been developed. Insects have several advantages unshared by mammals. Insects are sensitive, cheap to produce and can be conditioned with impressive speed for a specific chemical-detection task. Moreover, insects might be a preferred sensing method in scenarios that are deemed too dangerous to use mammals. The purpose of this review is to provide an overview of the biosensors used in forensic sciences.

  4. A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor.

    Lee, Jieun; Jang, Jaeman; Choi, Bongsik; Yoon, Jinsu; Kim, Jee-Yeon; Choi, Yang-Kyu; Kim, Dong Myong; Kim, Dae Hwan; Choi, Sung-Jin

    2015-07-21

    This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response of field-effect-transistor (FET)-based biosensors. The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential advantage of high density and low noise performance. The biosensor shows a current response of 5.74 decades per pH for pH detection, which is 2.5 × 10(5) times larger than that of a single SiNW sensor. In addition, we demonstrate charged polymer detection using the biosensor, with a high current change of 4.5 × 10(5) with a 500 nM concentration of poly(allylamine hydrochloride). In addition, we demonstrate a wide dynamic range can be obtained by adjusting the liquid gate voltage. We expect that this biosensor will be advantageous and practical for biosensor applications which requires lower noise, high speed, and high density.

  5. Biosensors: Future Analytical Tools

    Vikas

    2007-02-01

    Full Text Available Biosensors offer considerable promises for attaining the analytic information in a faster, simpler and cheaper manner compared to conventional assays. Biosensing approach is rapidly advancing and applications ranging from metabolite, biological/ chemical warfare agent, food pathogens and adulterant detection to genetic screening and programmed drug delivery have been demonstrated. Innovative efforts, coupling micromachining and nanofabrication may lead to even more powerful devices that would accelerate the realization of large-scale and routine screening. With gradual increase in commercialization a wide range of new biosensors are thus expected to reach the market in the coming years.

  6. Electroacoustic miniaturized DNA-biosensor.

    Gamby, Jean; Lazerges, Mathieu; Pernelle, Christine; Perrot, Hubert; Girault, Hubert H; Tribollet, Bernard

    2007-11-01

    A micrometer-sized electroacoustic DNA-biosensor was developed. The device included a thin semi-crystalline polyethylene terephthalate (PET) dielectric layer with two Ag microband electrodes on one side and a DNA thiol-labeled monolayer adsorbed on a gold surface on the other. A resonance wave was observed at 29 MHz with a network analyzer, upon AC voltage application between the two Ag electrodes, corresponding to electromechanical coupling induced by molecular dipoles of the PET polymer chain in the dielectric layer. It was found that the device size and geometry were well adapted to detect DNA hybridization, by measuring the capacity of the resonance response evolution: hybridization induced polarization of the dielectric material that affected the electromechanical coupling established in the dielectric layer. The 0.2 mm(2) sensor sensitive area allows detection in small volumes and still has higher detection levels for bioanalytical applications, the non-contact configuration adopted avoids electric faradic reactions that may damage biosensor sensitive layers, and finally, PET is a costless raw material, easy to process and well adapted for large scale production. The well-balanced technological and economic advantages of this kind of device make it a good candidate for biochip integration.

  7. Modeling of Complex Material Systems in Extreme Environments for Space Technology

    National Aeronautics and Space Administration — Among the many enabling technologies of space research is the design of materials which are stable in the environments of interest for a given application. At the...

  8. The Canadian Space Agency, Space Station, Strategic Technologies for Automation and Robotics Program technology development activity in protection of materials from the low Earth orbit space environment

    Francoeur, J. R.

    1992-01-01

    The Strategic Technologies in Automation and Robotics (STEAR) program is managing a number of development contracts to improve the protection of spacecraft materials from the Low Earth Orbit (LEO) space environment. The project is structured in two phases over a 3 to 4 year period with a budget of 3 to 4 million dollars. Phase 1 is designed to demonstrate the technical feasibility and commercial potential of a coating/substrate system and its associated application process. The objective is to demonstrate a prototype fabrication capability using a full scale component of a commercially viable process for the protection of materials and surface finishes from the LEO space environment, and to demonstrate compliance with a set of performance requirements. Only phase 1 will be discussed in this paper.

  9. Electrochemical biosensors for hormone analyses.

    Bahadır, Elif Burcu; Sezgintürk, Mustafa Kemal

    2015-06-15

    Electrochemical biosensors have a unique place in determination of hormones due to simplicity, sensitivity, portability and ease of operation. Unlike chromatographic techniques, electrochemical techniques used do not require pre-treatment. Electrochemical biosensors are based on amperometric, potentiometric, impedimetric, and conductometric principle. Amperometric technique is a commonly used one. Although electrochemical biosensors offer a great selectivity and sensitivity for early clinical analysis, the poor reproducible results, difficult regeneration steps remain primary challenges to the commercialization of these biosensors. This review summarizes electrochemical (amperometric, potentiometric, impedimetric and conductometric) biosensors for hormone detection for the first time in the literature. After a brief description of the hormones, the immobilization steps and analytical performance of these biosensors are summarized. Linear ranges, LODs, reproducibilities, regenerations of developed biosensors are compared. Future outlooks in this area are also discussed. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Tourism, technology and narratives: Reflections for the design of tourist spaces

    de Villasante García, Rafael; Casellas Oriol, Sílvia

    2017-01-01

    We characterize tourism essentially as a phenomenon of communication between architecture, a territory, a space and its visitors. The design of tourist spaces has evolved over time, according to the technologies used to build them. The emergence of new technologies enables new interactions with our environment and a constant connection with sources of information, in addition to geo-location and augmented reality. These are technologies that are re-configuring the tourist space and, therefore...

  11. The applicability of DOE solar cell and array technology to space power

    Scott-Monck, J. A.; Stella, P. M.; Berman, P. A.

    1980-01-01

    An evaluation of the main terrestrial photovoltaic development projects was performed. Technologies that may have applicability to space power are identified. Where appropriate, recommendations are made for programs to capitalize on developed technology. It is concluded that while the funding expended by DOE is considerably greater than the space (NASA and DOD) budget for photovoltaics, the terrestrial goals and the means for satisfying them are sufficiently different from space needs that little direct benefit currently exists for space applications.

  12. A cooperative power trading system based on satisfaction space technology

    Matsumoto, K.; Maruo, T.; Mori, N.

    2006-01-01

    This paper proposed a new power trading system model designed to ensure customer cooperation with power suppliers. Designed as an Internet application, the cooperative power trading system modelled power markets using a satisfaction space technology A network model of electric power trading systems was developed to create a communication network system that consisted of suppliers, customers, and auctioneers. When demand exceeded supply, the auctioneer in the trading system requested power reductions from customers. Rewards were paid to maintain the degree of satisfaction of the customers. The supplier's evaluation function was defined as a function of market price and power supply. A power reducing method was developed using a combinatorial optimization technique. Suppliers and customers submitted bids for initial power trading quantities, while the auctioneer decided a market price based on bidding values. After receiving the market price, suppliers and customers submitted a second set of bids for expected power trading quantities. A power reduction plan was then developed by the auctioneer to balance the amount of power supply and demand. The system can be applied to customers whose evaluation functions cannot be estimated beforehand, as the auctioneer was able to choose the most efficient power reduction point selected by consumers using a maximum steep slope method. Simulations conducted to validate the trading system demonstrated that the system is capable of choosing efficient energy reduction plans. 6 refs., 4 tabs., 3 figs

  13. Definition of technology development missions for early space station, orbit transfer vehicle servicing, volume 2

    1983-01-01

    Propellant transfer, storage, and reliquefaction TDM; docking and berthing technology development mission; maintenance technology development mission; OTV/payload integration, space station interface/accommodations; combined TDM conceptual design; programmatic analysis; and TDM equipment usage are discussed.

  14. NASA 20th Century Explorer . . . Into the Sea of Space. A Guide to Careers in Aero-Space Technology.

    National Aeronautics and Space Administration, Washington, DC.

    This pamphlet lists career opportunities in aerospace technology announced by the Boards of the U. S. Civil Service for the National Aeronautics and Space Administration (NASA). Information given includes (1) the work of the NASA, (2) technical and administrative specialties in aerospace technology, (3) educational and experience requirements, and…

  15. Multi-Agent Technology for Air Space Deconfliction

    Skormin, Victor

    2008-01-01

    .... It is a project specifically dedicated to the problem of air traffic control within airport air space in emergency situations when a hijacked aircraft appears and operates in the airport air space...

  16. Advanced Gas Sensing Technology for Space Suits, Phase I

    National Aeronautics and Space Administration — Advanced space suits require lightweight, low-power, durable sensors for monitoring critical life support materials. No current compact sensors have the tolerance...

  17. Interdigitated electrodes as impedance and capacitance biosensors: A review

    Mazlan, N. S.; Ramli, M. M.; Abdullah, M. M. A. B.; Halin, D. S. C.; Isa, S. S. M.; Talip, L. F. A.; Danial, N. S.; Murad, S. A. Z.

    2017-09-01

    Interdigitated electrodes (IDEs) are made of two individually addressable interdigitated comb-like electrode structures. IDEs are one of the most favored transducers, widely utilized in technological applications especially in the field of biological and chemical sensors due to their inexpensive, ease of fabrication process and high sensitivity. In order to detect and analyze a biochemical molecule or analyte, the impedance and capacitance signal need to be obtained. This paper investigates the working principle and influencer of the impedance and capacitance biosensors. The impedance biosensor depends on the resistance and capacitance while the capacitance biosensor influenced by the dielectric permittivity. However, the geometry and structures of the interdigitated electrodes affect both impedance and capacitance biosensor. The details have been discussed in this paper.

  18. Applications of commercial biosensors in clinical, food, environmental, and biothreat/biowarfare analyses.

    Bahadır, Elif Burcu; Sezgintürk, Mustafa Kemal

    2015-06-01

    The lack of specific, low-cost, rapid, sensitive, and easy detection of biomolecules has resulted in the development of biosensor technology. Innovations in biosensor technology have enabled many biosensors to be commercialized and have enabled biomolecules to be detected onsite. Moreover, the emerging technologies of lab-on-a-chip microdevices and nanosensors offer opportunities for the development of new biosensors with much better performance. Biosensors were first introduced into the laboratory by Clark and Lyons. They developed the first glucose biosensor for laboratory conditions. Then in 1973, a glucose biosensor was commercialized by Yellow Springs Instruments. The commercial biosensors have small size and simple construction and they are ideal for point-of-care biosensing. In addition to glucose, a wide variety of metabolites such as lactate, cholesterol, and creatinine can be detected by using commercial biosensors. Like the glucose biosensors (tests) other commercial tests such as for pregnancy (hCG), Escherichia coli O157, influenza A and B viruses, Helicobacter pylori, human immunodeficiency virus, tuberculosis, and malaria have achieved success. Apart from their use in clinical analysis, commercial tests are also used in environmental (such as biochemical oxygen demand, nitrate, pesticide), food (such as glutamate, glutamine, sucrose, lactose, alcohol, ascorbic acid), and biothreat/biowarfare (Bacillus anthracis, Salmonella, Botulinum toxin) analysis. In this review, commercial biosensors in clinical, environmental, food, and biowarfare analysis are summarized and the commercial biosensors are compared in terms of their important characteristics. This is the first review in which all the commercially available tests are compiled together. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Studies on Development of Space Kimchi Using Radiation Fusion Technology with Food Technology

    Lee, Ju Woon; Byun, Myung Woo; Kim, Jae Hun; Song, Beom Seok; Park, Jin Kyu; Park, Jae Nam

    2007-04-01

    Kimchi is Korean traditional fermented vegetable, it was known to one of health food through the world 5 sorts and to one of culture bequest of 100 kinds. In this study, it was conducted to development of Korean space food. Object of the study is development of food processed technology for long term storage and stability of supply at severe environment such as space, desert, deep sea. Irradiation technology is cold sterilization method, and it is able to fusion with the other food manufacturing and additives using method. Therefore, this study can offer to basic information for development of Korean space food. Side by side, it was expected that preceding results were able to wide utilization extension such as export of cured fermentation food. This study was conducted to evaluate the combined effects of additives (A), N2-packaging (N 2 ), mild heating at 60 .deg. C (HT) and gamma irradiation of 25 kGy (IR) at frozen state (F) on the shelf stability and quality of Kimchi during storage at 35 .deg. C for 30 days. Briefly, combination treatment of heat and irradiation was considered as the effective method to improve the shelf-stability of Kimchi. However, sensory quality was decreased. After all, irradiation was conducted at Kimchi samples for quality maintenance after gas exchange packaging method such as N 2 -packaging, quick freezing(-70 .deg. C). Therefore, the combination treatment was effected to insurance of shelf-life and satisfaction of quality. But other methods needed for inhibition deterioration of texture. Calcium lactate and vitamin C were added at Kimchi for prevention of softening, oleoresin paprika and artificial Kimchi flavor were added for improvement of sensory quality decreased by severe sterilization

  20. Studies on Development of Space Kimchi Using Radiation Fusion Technology with Food Technology

    Lee, Ju Woon; Byun, Myung Woo; Kim, Jae Hun; Song, Beom Seok; Park, Jin Kyu; Park, Jae Nam

    2007-04-15

    Kimchi is Korean traditional fermented vegetable, it was known to one of health food through the world 5 sorts and to one of culture bequest of 100 kinds. In this study, it was conducted to development of Korean space food. Object of the study is development of food processed technology for long term storage and stability of supply at severe environment such as space, desert, deep sea. Irradiation technology is cold sterilization method, and it is able to fusion with the other food manufacturing and additives using method. Therefore, this study can offer to basic information for development of Korean space food. Side by side, it was expected that preceding results were able to wide utilization extension such as export of cured fermentation food. This study was conducted to evaluate the combined effects of additives (A), N2-packaging (N{sub 2}), mild heating at 60 .deg. C (HT) and gamma irradiation of 25 kGy (IR) at frozen state (F) on the shelf stability and quality of Kimchi during storage at 35 .deg. C for 30 days. Briefly, combination treatment of heat and irradiation was considered as the effective method to improve the shelf-stability of Kimchi. However, sensory quality was decreased. After all, irradiation was conducted at Kimchi samples for quality maintenance after gas exchange packaging method such as N{sub 2}-packaging, quick freezing(-70 .deg. C). Therefore, the combination treatment was effected to insurance of shelf-life and satisfaction of quality. But other methods needed for inhibition deterioration of texture. Calcium lactate and vitamin C were added at Kimchi for prevention of softening, oleoresin paprika and artificial Kimchi flavor were added for improvement of sensory quality decreased by severe sterilization.

  1. Chart links solar, geophysical events with impacts on space technologies

    Davenport, George R.

    While developing a Space Weather Training Program for Air Force Space Command and the 50th Weather Squadron, both based in Colorado, ARINC Incorporated produced a flowchart that correlates solar and geophysical events with their impacts on Air Force systems.Personnel from both organizations collaborated in the development of the flowchart and provided many comments and suggestions. The model became the centerpiece of the Space Environment Impacts Reference Pamphlet, as well as the formal Space Weather Training Program. Although it is not a numerical or computer model, the flowchart became known as the “Space Environmental Impacts Model.”

  2. Definition of technology development missions for early space station satellite servicing, volume 1

    1983-01-01

    The testbed role of an early manned space station in the context of a satellite servicing evolutionary development and flight demonstration technology plan which results in a satellite servicing operational capability is defined. A satellite servicing technology development mission (a set of missions) to be performed on an early manned space station is conceptually defined.

  3. Research in space science and technology. Semiannual progress report

    Beckley, L.E.

    1977-08-01

    Progress in various space flight research programs is reported. Emphasis is placed on X-ray astronomy and interplanetary plasma physics. Topics covered include infrared astronomy, long base line interferometry, geological spectroscopy, space life science experiments, atmospheric physics, and space based materials and structures research. Analysis of galactic and extra-galactic X-ray data from the Small Astronomy Satellite (SAS-3) and HEAO-A and interplanetary plasma data for Mariner 10, Explorers 47 and 50, and Solrad is discussed

  4. Recent advances in ZnO nanostructures and thin films for biosensor applications: Review

    Arya, Sunil K.; Saha, Shibu; Ramirez-Vick, Jaime E.; Gupta, Vinay; Bhansali, Shekhar; Singh, Surinder P.

    2012-01-01

    Graphical abstract: ZnO nanostructures have shown binding of biomolecules in desired orientation with improved conformation and high biological activity, resulting in enhanced sensing characteristics. Furthermore, their compatibility with complementary metal oxide semiconductor technology for constructing integrated circuits makes them suitable candidate for future small integrated biosensor devices. This review highlights various approaches to synthesize ZnO nanostructures and thin films, and their applications in biosensor technology. Highlights: ► This review highlights various approaches to synthesize ZnO nanostructures and thin films. ► Article highlights the importance of ZnO nanostructures as biosensor matrix. ► Article highlights the advances in various biosensors based on ZnO nanostructures. ► Article describes the potential of ZnO based biosensor for new generation healthcare devices. - Abstract: Biosensors have shown great potential for health care and environmental monitoring. The performance of biosensors depends on their components, among which the matrix material, i.e., the layer between the recognition layer of biomolecule and transducer, plays a crucial role in defining the stability, sensitivity and shelf-life of a biosensor. Recently, zinc oxide (ZnO) nanostructures and thin films have attracted much interest as materials for biosensors due to their biocompatibility, chemical stability, high isoelectric point, electrochemical activity, high electron mobility, ease of synthesis by diverse methods and high surface-to-volume ratio. ZnO nanostructures have shown the binding of biomolecules in desired orientations with improved conformation and high biological activity, resulting in enhanced sensing characteristics. Furthermore, compatibility with complementary metal oxide semiconductor technology for constructing integrated circuits makes ZnO nanostructures suitable candidate for future small integrated biosensor devices. This review

  5. Recent advances in ZnO nanostructures and thin films for biosensor applications: Review

    Arya, Sunil K., E-mail: sunilarya333@gmail.com [Bioelectronics Program, Institute of Microelectronics, A-Star 11 Science Park Road, Singapore Science Park II, Singapore 117685 (Singapore); Saha, Shibu [Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India); Ramirez-Vick, Jaime E. [Engineering Science and Materials Department, University of Puerto Rico, Mayaguez, PR 00681 (United States); Gupta, Vinay [Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India); Bhansali, Shekhar [Department of Electrical and Computer Engineering, Florida International University, Miami, FL (United States); Singh, Surinder P., E-mail: singh.uprm@gmail.com [National Physical Laboratory, Dr K.S. Krishnan Marg, New Delhi 110012 (India)

    2012-08-06

    Graphical abstract: ZnO nanostructures have shown binding of biomolecules in desired orientation with improved conformation and high biological activity, resulting in enhanced sensing characteristics. Furthermore, their compatibility with complementary metal oxide semiconductor technology for constructing integrated circuits makes them suitable candidate for future small integrated biosensor devices. This review highlights various approaches to synthesize ZnO nanostructures and thin films, and their applications in biosensor technology. Highlights: Black-Right-Pointing-Pointer This review highlights various approaches to synthesize ZnO nanostructures and thin films. Black-Right-Pointing-Pointer Article highlights the importance of ZnO nanostructures as biosensor matrix. Black-Right-Pointing-Pointer Article highlights the advances in various biosensors based on ZnO nanostructures. Black-Right-Pointing-Pointer Article describes the potential of ZnO based biosensor for new generation healthcare devices. - Abstract: Biosensors have shown great potential for health care and environmental monitoring. The performance of biosensors depends on their components, among which the matrix material, i.e., the layer between the recognition layer of biomolecule and transducer, plays a crucial role in defining the stability, sensitivity and shelf-life of a biosensor. Recently, zinc oxide (ZnO) nanostructures and thin films have attracted much interest as materials for biosensors due to their biocompatibility, chemical stability, high isoelectric point, electrochemical activity, high electron mobility, ease of synthesis by diverse methods and high surface-to-volume ratio. ZnO nanostructures have shown the binding of biomolecules in desired orientations with improved conformation and high biological activity, resulting in enhanced sensing characteristics. Furthermore, compatibility with complementary metal oxide semiconductor technology for constructing integrated circuits makes Zn

  6. Electrochemical biosensors in pharmaceutical analysis

    Gil, Eric de Souza; Melo, Giselle Rodrigues de

    2010-01-01

    Given the increasing demand for practical and low-cost analytical techniques, biosensors have attracted attention for use in the quality analysis of drugs, medicines, and other analytes of interest in the pharmaceutical area. Biosensors allow quantification not only of the active component in pharmaceutical formulations, but also the analysis of degradation products and metabolites in biological fluids. Thus, this article presents a brief review of biosensor use in pharmaceutical analysis, fo...

  7. Protease biosensors based on peptide-nanocellulose conjugates: from molecular design to dressing interface

    The development of point of care diagnostic protease sensors applied to wound healing has received increased interest for chronic wound treatment and as an interface with chronic wound dressings. Biosensor technology has grown exponentially in recent years. Here we focus on nanocelluosic biosensor t...

  8. Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors

    Teigell Beneitez, N.; Missinne, J.; Schleipen, J.J.H.B.; Orsel, J.G.; Prins, M.W.J.; Steenberge, Van G.; Cartwright, A.N.; Nicolau, D.V.

    2010-01-01

    We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample

  9. Abstracts of the international scientific-practical conference on space research, technology and conversion-II

    1997-04-01

    The International Conference on space research, technology and conversion-II was held on 16-18 April, 1997 in Tashkent, Uzbekistan. The specialists discussed various aspects of space research, technology and conversion problems. More than 60 talks were presented in the meeting on the following subjects: remote sensing and the processing of satellite information; space navigation and others, including radiation effects in silicon solar cells caused by cosmic radiation. (A.A.D.)

  10. Emerging Geospatial Sharing Technologies in Earth and Space Science Informatics

    Singh, R.; Bermudez, L. E.

    2013-12-01

    Emerging Geospatial Sharing Technologies in Earth and Space Science Informatics The Open Geospatial Consortium (OGC) mission is to serve as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The OGC coordinates with over 400 institutions in the development of geospatial standards. In the last years two main trends are making disruptions in geospatial applications: mobile and context sharing. People now have more and more mobile devices to support their work and personal life. Mobile devices are intermittently connected to the internet and have smaller computing capacity than a desktop computer. Based on this trend a new OGC file format standard called GeoPackage will enable greater geospatial data sharing on mobile devices. GeoPackage is perhaps best understood as the natural evolution of Shapefiles, which have been the predominant lightweight geodata sharing format for two decades. However the format is extremely limited. Four major shortcomings are that only vector points, lines, and polygons are supported; property names are constrained by the dBASE format; multiple files are required to encode a single data set; and multiple Shapefiles are required to encode multiple data sets. A more modern lingua franca for geospatial data is long overdue. GeoPackage fills this need with support for vector data, image tile matrices, and raster data. And it builds upon a database container - SQLite - that's self-contained, single-file, cross-platform, serverless, transactional, and open source. A GeoPackage, in essence, is a set of SQLite database tables whose content and layout is described in the candidate GeoPackage Implementation Specification available at https://portal.opengeospatial.org/files/?artifact_id=54838&version=1. The second trend is sharing client 'contexts'. When a user is looking into an article or a product on the web

  11. Research in space commercialization, technology transfer and communications, vol. 2

    Dunn, D. A.; Agnew, C. E.

    1983-01-01

    Spectrum management, models for evaluating communications systems, and implications of communications regulations for NASA are considered as major parts of communications policy. Marketing LANDSAT products in developing countries, a political systems analysis of LANDSAT, and private financing and operation of the space operations center (space station) are discussed. Investment requirements, risks, government support, and other primary business and management considerations are examined.

  12. Space Technology Demonstrations Using Low Cost, Short-Schedule Airborne and Range Facilities at the Dryden Flight Research Center

    Carter, John; Kelly, John; Jones, Dan; Lee, James

    2013-01-01

    There is a national effort to expedite advanced space technologies on new space systems for both government and commercial applications. In order to lower risk, these technologies should be demonstrated in a relevant environment before being installed in new space systems. This presentation introduces several low cost, short schedule space technology demonstrations using airborne and range facilities available at the Dryden Flight Research Center.

  13. Carbon nanotube biosensors

    Tîlmaciu, Carmen-Mihaela; Morris, May C.

    2015-01-01

    Nanomaterials possess unique features which make them particularly attractive for biosensing applications. In particular, carbon nanotubes (CNTs) can serve as scaffolds for immobilization of biomolecules at their surface, and combine several exceptional physical, chemical, electrical, and optical characteristics properties which make them one of the best suited materials for the transduction of signals associated with the recognition of analytes, metabolites, or disease biomarkers. Here we provide a comprehensive review on these carbon nanostructures, in which we describe their structural and physical properties, functionalization and cellular uptake, biocompatibility, and toxicity issues. We further review historical developments in the field of biosensors, and describe the different types of biosensors which have been developed over time, with specific focus on CNT-conjugates engineered for biosensing applications, and in particular detection of cancer biomarkers. PMID:26579509

  14. Carbon Nanotube Biosensors

    Carmen-Mihaela eTilmaciu

    2015-10-01

    Full Text Available Nanomaterials possess unique features which make them particularly attractive for biosensing applications. In particular Carbon Nanotubes (CNTs can serve as scaffolds for immobilization of biomolecules at their surface, and combine several exceptional physical, chemical, electrical and optical characteristics properties which make them one of the best suited materials for the transduction of signals associated with the recognition of analytes, metabolites or disease biomarkers. Here we provide a comprehensive review on these carbon nanostructures, in which we will describe their structural and physical properties, discuss functionalization and cellular uptake, biocompatibility and toxicity issues. We further review historical developments in the field of biosensors, and describe the different types of biosensors which have been developed over time, with specific focus on CNT-conjugates engineered for biosensing applications, and in particular detection of cancer biomarkers.

  15. Synthetic Electric Microbial Biosensors

    2017-06-10

    domains and DNA-binding domains into a single protein for deregulation of down stream genes of have been favored [10]. Initially experiments with... Germany DISTRIBUTION A. Approved for public release: distribution unlimited.   Talk title: “Synthetic biology based microbial biosensors for the...toolbox” in Heidelberg, Germany Poster title: “Anaerobic whole cell microbial biosensors” Link: http://phdsymposium.embl.org/#home   September, 2014

  16. Biosensor. Seitai sensa

    Karube, I [The Univ. of Tokyo, Tokyo (Japan). Research Center for Advanced Science and Technology

    1993-06-15

    Present state of the art of biosensors is described by taking taste sensors and odor sensors as examples. Bio-devices that response only to specific chemical substances are made using membranes that recognize particular molecules. Biosensors are constructed in combination of bio-devices with electronics devices that transduce the response of bio-devices to electric signals. Enzymes are used often as bio-devices to recognize molecules. They recognize strictly chemical substances and promote chemical reactions. Devices to measure electrochemically substances consumed or produced in the reactions serve as sensors. For taste sensors, inosinic acid or glutamic acid that is a component of taste, is recognized and measured. Combination of various bio-devices other than enzymes with various transducers makes it possible to produce biosensors based on a variety of principles. Odor sensors recognize odors by measuring frequency change of the electrode of quartz oscillator. The change occurs with weight change due to odorous substances absorbed on the oscillator electrode coated with lipids which exist in olfactory cells. 1 ref., 1 fig.

  17. Grand Challenges in Space Technology: Distributed Satellite Systems

    Miller, David

    2001-01-01

    The MITIAFRL Distributed Satellite Systems program examines the motivation, analysis and development of technology associated with the distribution of assets and functionality over a number of cooperating satellites...

  18. Thermal Energy for Space Cooling--Federal Technology Alert

    Brown, Daryl R.

    2000-12-31

    Cool storage technology can be used to significantly reduce energy costs by allowing energy-intensive, electrically driven cooling equipment to be predominantly operated during off peak hours when electricity rates are lower. This Federal Technology Alert, which is sponsored by DOE's Federal Energy Management Program (FEMP), describes the basic types of cool storage technologies and cooling system integration options. In addition, it defines the savings potential in the federal sector, presents application advice, and describes the performance experience of specific federal users. The results of a case study of a GSA building using cool storage technology are also provided.

  19. In-Space Propulsion (ISP) Solar Sail Propulsion Technology Development

    Montgomery, Edward E., IV

    2004-01-01

    An overview of the rationale and content for Solar Sail Propulsion (SSP), the on-going project to advance solar technology from technology readiness level 3 to 6 will be provided. A descriptive summary of the major and minor component efforts underway will include identification of the technology providers and a listing of anticipated products Recent important results from major system ground demonstrators will be provided. Finally, a current status of all activities will provided along with the most recent roadmap for the SSP technology development program.

  20. Technology Estimating 2: A Process to Determine the Cost and Schedule of Space Technology Research and Development

    Cole, Stuart K.; Wallace, Jon; Schaffer, Mark; May, M. Scott; Greenberg, Marc W.

    2014-01-01

    As a leader in space technology research and development, NASA is continuing in the development of the Technology Estimating process, initiated in 2012, for estimating the cost and schedule of low maturity technology research and development, where the Technology Readiness Level is less than TRL 6. NASA' s Technology Roadmap areas consist of 14 technology areas. The focus of this continuing Technology Estimating effort included four Technology Areas (TA): TA3 Space Power and Energy Storage, TA4 Robotics, TA8 Instruments, and TA12 Materials, to confine the research to the most abundant data pool. This research report continues the development of technology estimating efforts completed during 2013-2014, and addresses the refinement of parameters selected and recommended for use in the estimating process, where the parameters developed are applicable to Cost Estimating Relationships (CERs) used in the parametric cost estimating analysis. This research addresses the architecture for administration of the Technology Cost and Scheduling Estimating tool, the parameters suggested for computer software adjunct to any technology area, and the identification of gaps in the Technology Estimating process.

  1. Medical support and technology for long-duration space missions

    Furukawa, S.; Nicogossian, A.; Buchanan, P.; Pool, S. L.

    1982-01-01

    The current philosophy and development directions being taken towards realization of medical systems for use on board space stations are discussed. Data was gained on the performance of physical examinations, venipuncture and blood flow, blood smear and staining, white blood cell differential count, throat culture swab and colony count, and microscopy techniques during a 28-day period of the Skylab mission. It is expected that the advent of Shuttle flights will rapidly increase the number of persons in space, create a demand for in-space rather than on-earth medical procedures, and necessitate treatments for disorders without the provision for an early return to earth. Attention is being given to pressurized environment and extravehicular conditions of treatment, the possibilities of the use of the OTV for moving injured or ill crewmembers to other space stations, and to isolation of persons with communicable diseases from station crews.

  2. Scalable Solution Processing of Pristine Carbon Nanotubes for Self-Assembled, Tunable Materials with Direct Application to Space Technologies

    National Aeronautics and Space Administration — Current material technologies limit space exploration and vehicle performance due to often unnecessary mass increase from copper wiring or heavy structural...

  3. Advancing automation and robotics technology for the space station and the US economy

    Cohen, A.

    1985-01-01

    In response to Public Law 98-371, dated July 18, 1984, the NASA Advanced Technology Advisory Committee has studied automation and rebotics for use in the space station. The Executive Overview, Volume 1 presents the major findings of the study and recommends to NASA principles for advancing automation and robotics technologies for the benefit of the space station and of the U.S. economy in general. As a result of its study, the Advanced Technology Advisory Committee believes that a key element of technology for the space station is extensive use of advanced general-purpose automation and robotics. These systems could provide the United States with important new methods of generating and exploiting space knowledge in commercial enterprises and thereby help preserve U.S. leadership in space.

  4. Monolithic Microwave Integrated Circuit (MMIC) technology for space communications applications

    Connolly, Denis J.; Bhasin, Kul B.; Romanofsky, Robert R.

    1987-01-01

    Future communications satellites are likely to use gallium arsenide (GaAs) monolithic microwave integrated-circuit (MMIC) technology in most, if not all, communications payload subsystems. Multiple-scanning-beam antenna systems are expected to use GaAs MMIC's to increase functional capability, to reduce volume, weight, and cost, and to greatly improve system reliability. RF and IF matrix switch technology based on GaAs MMIC's is also being developed for these reasons. MMIC technology, including gigabit-rate GaAs digital integrated circuits, offers substantial advantages in power consumption and weight over silicon technologies for high-throughput, on-board baseband processor systems. For the more distant future pseudomorphic indium gallium arsenide (InGaAs) and other advanced III-V materials offer the possibility of MMIC subsystems well up into the millimeter wavelength region. All of these technology elements are in NASA's MMIC program. Their status is reviewed.

  5. Discussion on Application of Space Materials and Technological Innovation in Dynamic Fashion Show

    Huo, Meilin; Kim, Chul Soo; Zhao, Wenhan

    2018-03-01

    In modern dynamic fashion show, designers often use the latest ideas and technology, and spend their energy in stage effect and overall environment to make audience’s watching a fashion show like an audio-visual feast. With rapid development of China’s science and technology, it has become a design trend to strengthen the relationship between new ideas, new trends and technology in modern art. With emergence of new technology, new methods and new materials, designers for dynamic fashion show stage art can choose the materials with an increasingly large scope. Generation of new technology has also made designers constantly innovate the stage space design means, and made the stage space design innovated constantly on the original basis of experiences. The dynamic clothing display space is on design of clothing display space, layout, platform decoration style, platform models, performing colors, light arrangement, platform background, etc.

  6. Engineering the bioelectrochemical interface using functional nanomaterials and microchip technique toward sensitive and portable electrochemical biosensors.

    Jia, Xiaofang; Dong, Shaojun; Wang, Erkang

    2016-02-15

    Electrochemical biosensors have played active roles at the forefront of bioanalysis because they have the potential to achieve sensitive, specific and low-cost detection of biomolecules and many others. Engineering the electrochemical sensing interface with functional nanomaterials leads to novel electrochemical biosensors with improved performances in terms of sensitivity, selectivity, stability and simplicity. Functional nanomaterials possess good conductivity, catalytic activity, biocompatibility and high surface area. Coupled with bio-recognition elements, these features can amplify signal transduction and biorecognition events, resulting in highly sensitive biosensing. Additionally, microfluidic electrochemical biosensors have attracted considerable attention on account of their miniature, portable and low-cost systems as well as high fabrication throughput and ease of scaleup. For example, electrochemical enzymetic biosensors and aptamer biosensors (aptasensors) based on the integrated microchip can be used for portable point-of-care diagnostics and environmental monitoring. This review is a summary of our recent progress in the field of electrochemical biosensors, including aptasensors, cytosensors, enzymatic biosensors and self-powered biosensors based on biofuel cells. We presented the advantages that functional nanomaterials and microfluidic chip technology bring to the electrochemical biosensors, together with future prospects and possible challenges. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Development of Countermeasure and Application technologies to Space Radiation

    Lee, Ju Woon; Byun, Myung Woo; Kim, Jae Hun

    2009-02-01

    Basic studies to evaluate the microbial activity changes by irradiation, and identify the composting microorganisms using the hyperthermal composter were conducted. And establishment of research protocols on muscle atrophy mechanism using two-dimensional electrophoresis and various blotting analyses are conducted. And two bio-active molecules that potentially play an preventive role of muscle atrophy are uncovered. Integrative protocols linking between the effect of bio-active molecules and treadmill exercise for muscle atrophy inhibition are established. And, successful induction of hibernation-like animation (reduction in body temperature and heartbeat rate) were monitored after HIT injection to mice. The space Bibimbap was developed by a combination treatment of 0.4% baking powder, soaking for 45 min, cooking, freezing, and packaging. It could be consumed easily after rehydration for 10 with 70 .deg. C water, which can be supplied from the International Space Station. And Bulgogi steak developed by combination treatment of packaging, freezing, antioxidant, charcoal and irradiation is a ready-to-eat type and has long shelf-life at the room temperature. Four foods items (Kimchi, Ramen, Saengshik bar, Sujeonggwa) were certified for the use in space flight conditions of 30 days by IBMP to be supplied to the first Korean astronaut, So-Yeon Lee, who accomplished space missions (sensory comparison test) at the International Space Station in 2008. To participate in the nutritional and physiological evaluation of Korean space foods in the MARS-500 project and evaluation of growth change in radio-durable micro organisms and plant seeds by space flight using BION-M1 satellite, a series of meeting were held in Russia and Korea

  8. Development of Countermeasure and Application technologies to Space Radiation

    Lee, Ju Woon; Byun, Myung Woo; Kim, Jae Hun

    2009-02-15

    Basic studies to evaluate the microbial activity changes by irradiation, and identify the composting microorganisms using the hyperthermal composter were conducted. And establishment of research protocols on muscle atrophy mechanism using two-dimensional electrophoresis and various blotting analyses are conducted. And two bio-active molecules that potentially play an preventive role of muscle atrophy are uncovered. Integrative protocols linking between the effect of bio-active molecules and treadmill exercise for muscle atrophy inhibition are established. And, successful induction of hibernation-like animation (reduction in body temperature and heartbeat rate) were monitored after HIT injection to mice. The space Bibimbap was developed by a combination treatment of 0.4% baking powder, soaking for 45 min, cooking, freezing, and packaging. It could be consumed easily after rehydration for 10 with 70 .deg. C water, which can be supplied from the International Space Station. And Bulgogi steak developed by combination treatment of packaging, freezing, antioxidant, charcoal and irradiation is a ready-to-eat type and has long shelf-life at the room temperature. Four foods items (Kimchi, Ramen, Saengshik bar, Sujeonggwa) were certified for the use in space flight conditions of 30 days by IBMP to be supplied to the first Korean astronaut, So-Yeon Lee, who accomplished space missions (sensory comparison test) at the International Space Station in 2008. To participate in the nutritional and physiological evaluation of Korean space foods in the MARS-500 project and evaluation of growth change in radio-durable micro organisms and plant seeds by space flight using BION-M1 satellite, a series of meeting were held in Russia and Korea

  9. Ecological aspects of the space-rocket technology effect on the magnetosphere and the near space

    Shushkova, V.B.; Khanan'yan, A.A.

    1991-01-01

    A brief review of the main types of authropogenic contamination of near-Earth space, linked with destruction of space vehicles and propulsion system operation is given. It is mentioned, that fragments of artificial origin including radioactive ones, represent a real danger now, while global changes of the environment (ionosphere exhaustion, exosphere density increase, climatic changes, etc.) can take place under the further intensification of space activity

  10. Protein Detection with Aptamer Biosensors

    Regina Stoltenburg

    2008-07-01

    Full Text Available Aptamers have been developed for different applications. Their use as new biological recognition elements in biosensors promises progress for fast and easy detection of proteins. This new generation of biosensor (aptasensors will be more stable and well adapted to the conditions of real samples because of the specific properties of aptamers.

  11. Dual-Use Space Technology Transfer Conference and Exhibition. Volume 2

    Krishen, Kumar (Compiler)

    1994-01-01

    This is the second volume of papers presented at the Dual-Use Space Technology Transfer Conference and Exhibition held at the Johnson Space Center February 1-3, 1994. Possible technology transfers covered during the conference were in the areas of information access; innovative microwave and optical applications; materials and structures; marketing and barriers; intelligent systems; human factors and habitation; communications and data systems; business process and technology transfer; software engineering; biotechnology and advanced bioinstrumentation; communications signal processing and analysis; medical care; applications derived from control center data systems; human performance evaluation; technology transfer methods; mathematics, modeling, and simulation; propulsion; software analysis and decision tools; systems/processes in human support technology; networks, control centers, and distributed systems; power; rapid development; perception and vision technologies; integrated vehicle health management; automation technologies; advanced avionics; and robotics technologies.

  12. Dual-Use Space Technology Transfer Conference and Exhibition. Volume 1

    Krishen, Kumar (Compiler)

    1994-01-01

    This document contains papers presented at the Dual-Use Space Technology Transfer Conference and Exhibition held at the Johnson Space Center February 1-3, 1994. Possible technology transfers covered during the conference were in the areas of information access; innovative microwave and optical applications; materials and structures; marketing and barriers; intelligent systems; human factors and habitation; communications and data systems; business process and technology transfer; software engineering; biotechnology and advanced bioinstrumentation; communications signal processing and analysis; new ways of doing business; medical care; applications derived from control center data systems; human performance evaluation; technology transfer methods; mathematics, modeling, and simulation; propulsion; software analysis and decision tools systems/processes in human support technology; networks, control centers, and distributed systems; power; rapid development perception and vision technologies; integrated vehicle health management; automation technologies; advanced avionics; ans robotics technologies. More than 77 papers, 20 presentations, and 20 exhibits covering various disciplines were presented b experts from NASA, universities, and industry.

  13. Research and technology: 1994 annual report of the John F. Kennedy Space Center

    1994-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1994 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities. The Technology Programs and Commercialization Office (DE-TPO), (407) 867-3017, is responsible for publication of this report and should be contacted for any desired information regarding the advanced technology program.

  14. Space power needs and forecasted technologies for the 1990s and beyond

    Buden, D.; Albert, T.

    1987-01-01

    A new generation of reactors for electric power will be available for space missions to satisfy military and civilian needs in the 1990s and beyond. To ensure a useful product, nuclear power plant development must be cognizant of other space power technologies. Major advances in solar and chemical technologies need to be considered in establishing the goals of future nuclear power plants. In addition, the mission needs are evolving into new regimes. Civilian and military power needs are forecasted to exceed anything used in space to date. Technology trend forecasts have been mapped as a function of time for solar, nuclear, chemical, and storage systems to illustrate areas where each technology provides minimum mass. Other system characteristics may dominate the usefulness of a technology on a given mission. This paper will discuss some of these factors, as well as forecast future military and civilian power needs and the status of technologies for the 1990s and 2000s. 6 references

  15. Solar and Space Physics: A Science for a Technological Society

    2013-01-01

    From the interior of the Sun, to the upper atmosphere and near-space environment of Earth, and outward to a region far beyond Pluto where the Sun's influence wanes, advances during the past decade in space physics and solar physics the disciplines NASA refers to as heliophysics have yielded spectacular insights into the phenomena that affect our home in space. This report, from the National Research Council's (NRC's) Committee for a Decadal Strategy in Solar and Space Physics, is the second NRC decadal survey in heliophysics. Building on the research accomplishments realized over the past decade, the report presents a program of basic and applied research for the period 2013-2022 that will improve scientific understanding of the mechanisms that drive the Sun's activity and the fundamental physical processes underlying near-Earth plasma dynamics, determine the physical interactions of Earth's atmospheric layers in the context of the connected Sun-Earth system, and enhance greatly the capability to provide realistic and specific forecasts of Earth's space environment that will better serve the needs of society. Although the recommended program is directed primarily to NASA (Science Mission Directorate -- Heliophysics Division) and the National Science Foundation (NSF) (Directorate for Geosciences -- Atmospheric and Geospace Sciences) for action, the report also recommends actions by other federal agencies, especially the National Oceanic and Atmospheric Administration (NOAA) those parts of NOAA charged with the day-to-day (operational) forecast of space weather. In addition to the recommendations included in this summary, related recommendations are presented in the main text of the report.

  16. SpaceWire model development technology for satellite architecture.

    Eldridge, John M.; Leemaster, Jacob Edward; Van Leeuwen, Brian P.

    2011-09-01

    Packet switched data communications networks that use distributed processing architectures have the potential to simplify the design and development of new, increasingly more sophisticated satellite payloads. In addition, the use of reconfigurable logic may reduce the amount of redundant hardware required in space-based applications without sacrificing reliability. These concepts were studied using software modeling and simulation, and the results are presented in this report. Models of the commercially available, packet switched data interconnect SpaceWire protocol were developed and used to create network simulations of data networks containing reconfigurable logic with traffic flows for timing system distribution.

  17. Paper-based Biosensor for Rapid Colorimetric Detection of Pathogenic Bacteria

    National Aeronautics and Space Administration — The current project proposes to develop a real-time method for identification of targeted microorganisms using a paper-based biosensor system with ease-of-use,...

  18. In-Space Manufacturing at NASA Marshall Space Flight Center: Enabling Technologies for Exploration

    Bean, Quincy; Johnston, Mallory; Ordonez, Erick; Ryan, Rick; Prater, Tracie; Werkeiser, Niki

    2015-01-01

    NASA Marshall Space Flight Center is currently engaged in a number of in-space manufacturing(ISM)activities that have the potential to reduce launch costs, enhance crew safety, and provide the capabilities needed to undertake long duration spaceflight safely and sustainably.

  19. In-Space Propulsion Technology Products for NASA's Future Science and Exploration Missions

    Anderson, David J.; Pencil, Eric; Peterson, Todd; Dankanich, John; Munk, Michelle M.

    2011-01-01

    Since 2001, the In-Space Propulsion Technology (ISPT) project has been developing and delivering in-space propulsion technologies that will enable or enhance NASA robotic science missions. These in-space propulsion technologies are applicable, and potentially enabling, for future NASA flagship and sample return missions currently being considered, as well as having broad applicability to future competed mission solicitations. The high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance for lower cost was completed in 2009. Two other ISPT technologies are nearing completion of their technology development phase: 1) NASA's Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; and 2) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells; aerothermal effect models: and atmospheric models for Earth, Titan, Mars and Venus. This paper provides status of the technology development, applicability, and availability of in-space propulsion technologies that have recently completed their technology development and will be ready for infusion into NASA s Discovery, New Frontiers, Science Mission Directorate (SMD) Flagship, and Exploration technology demonstration missions

  20. In-Space Propulsion Technology Products Ready for Infusion on NASA's Future Science Missions

    Anderson, David J.; Pencil, Eric; Peterson, Todd; Dankanich, John; Munk, Michele M.

    2012-01-01

    Since 2001, the In-Space Propulsion Technology (ISPT) program has been developing and delivering in-space propulsion technologies that will enable or enhance NASA robotic science missions. These in-space propulsion technologies are applicable, and potentially enabling, for future NASA flagship and sample return missions currently being considered. They have a broad applicability to future competed mission solicitations. The high-temperature Advanced Material Bipropellant Rocket (AMBR) engine, providing higher performance for lower cost, was completed in 2009. Two other ISPT technologies are nearing completion of their technology development phase: 1) NASA s Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; and 2) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells; aerothermal effect models; and atmospheric models for Earth, Titan, Mars and Venus. This paper provides status of the technology development, applicability, and availability of in-space propulsion technologies that have recently completed their technology development and will be ready for infusion into NASA s Discovery, New Frontiers, SMD Flagship, or technology demonstration missions.

  1. The Third International Symposium on Space Terahertz Technology: Symposium proceedings

    1992-01-01

    Papers from the symposium are presented that are relevant to the generation, detection, and use of the terahertz spectral region for space astronomy and remote sensing of the Earth's upper atmosphere. The program included thirteen sessions covering a wide variety of topics including solid-state oscillators, power-combining techniques, mixers, harmonic multipliers, antennas and antenna arrays, submillimeter receivers, and measurement techniques.

  2. Department of Defense Space Science and Technology Strategy 2015

    2015-01-01

    foundations for GPS; 2. The initial discovery and follow-on research on the operational impacts of solar coronal mass ejections and space experimental...based x-ray pulsar navigation and timing capability A-11 Table 4 Intelligence, Surveillance, and Reconnaissance Short Term S&T Goals

  3. Definition of technology development missions for early Space Station satellite servicing. Volume 2: Technical

    Cable, D. A.; Diewald, C. A.; Hills, T. C.; Parmentier, T. J.; Spencer, R. A.; Stone, G. E.

    1984-01-01

    Volume 2 contains the Technical Report of the approach and results of the Phase 2 study. The phase 2 servicing study was initiated in June 1983, and is being reported in this document. The scope of the contract was to: (1) define in detail five selected technology development missions (TDM); (2) conduct a design requirement analysis to refine definitions of satellite servicing requirements at the space station; and (3) develop a technology plan that would identify and schedule prerequisite precursor technology development, associated. STS flight experiments and space station experiments needed to provide onorbit validation of the evolving technology.

  4. A 100 kW-Class Technology Demonstrator for Space Solar Power

    Howell, J.; Carrington, C.; Day, G.

    2004-12-01

    A first step in the development of solar power from space is the flight demonstration of critical technologies. These fundamental technologies include efficient solar power collection and generation, power management and distribution, and thermal management. In addition, the integration and utilization of these technologies into a viable satellite bus could provide an energy-rich platform for a portfolio of payload experiments such as wireless power transmission (WPT). This paper presents the preliminary design of a concept for a 100 kW-class free-flying platform suitable for flight demonstration of Space Solar Power (SSP) technology experiments.

  5. Space station as a vital focus for advancing the technologies of automation and robotics

    Varsi, Giulio; Herman, Daniel H.

    1988-01-01

    A major guideline for the design of the U.S. Space Station is that the Space Station address a wide variety of functions. These functions include the servicing of unmanned assets in space, the support of commercial labs in space and the efficient management of the Space Station itself; the largest space asset. The technologies of Automation and Robotics have the promise to help in reducing Space Station operating costs and to achieve a highly efficient use of the human in space. The use of advanced automation and artificial intelligence techniques, such as expert systems, in Space Station subsystems for activity planning and failure mode management will enable us to reduce dependency on a mission control center and could ultimately result in breaking the umbilical link from Earth to the Space Station. The application of robotic technologies with advanced perception capability and hierarchical intelligent control to servicing system will enable the servicing of assets either in space or in situ with a high degree of human efficiency. The results of studies leading toward the formulation of an automation and robotics plan for Space Station development are presented.

  6. Progress in space nuclear reactor power systems technology development - The SP-100 program

    Davis, H. S.

    1984-01-01

    Activities related to the development of high-temperature compact nuclear reactors for space applications had reached a comparatively high level in the U.S. during the mid-1950s and 1960s, although only one U.S. nuclear reactor-powered spacecraft was actually launched. After 1973, very little effort was devoted to space nuclear reactor and propulsion systems. In February 1983, significant activities toward the development of the technology for space nuclear reactor power systems were resumed with the SP-100 Program. Specific SP-100 Program objectives are partly related to the determination of the potential performance limits for space nuclear power systems in 100-kWe and 1- to 100-MW electrical classes. Attention is given to potential missions and applications, regimes of possible space power applicability, safety considerations, conceptual system designs, the establishment of technical feasibility, nuclear technology, materials technology, and prospects for the future.

  7. Resilient backhaul network design using hybrid radio/free-space optical technology

    Douik, Ahmed; Dahrouj, Hayssam; Al-Naffouri, Tareq Y.; Alouini, Mohamed-Slim

    2016-01-01

    The radio-frequency (RF) technology is a scalable solution for the backhaul planning. However, its performance is limited in terms of data rate and latency. Free Space Optical (FSO) backhaul, on the other hand, offers a higher data rate

  8. Enabling Dedicated, Affordable Space Access Through Aggressive Technology Maturation

    Jones, Jonathan E.; Kibbey, Timothy P.; Cobb, C. Brent; Harris, Lawanna L.

    2014-01-01

    A launch vehicle at the scale and price point which allows developers to take reasonable risks with high payoff propulsion and avionics hardware solutions does not exist today. Establishing this service provides a ride through the proverbial technology "valley of death" that lies between demonstration in laboratory and flight environments. NASA's NanoLaunch effort will provide the framework to mature both earth-to-orbit and on-orbit propulsion and avionics technologies while also providing affordable, dedicated access to low earth orbit for cubesat class payloads.

  9. Future role and significance of space activities in reflection of global social, technological and economic trends

    Diekmann, Andreas; Richarz, Hans.-Peter

    The paper describes the interrelation of space activities and global socio-economic trends like "globalisation of markets" and "renaissance of fine arts". The interrelation reveals the economic strategic, technological and scientific dimension of space activities and their benefits to mankind. Then, the significance and perspectives of space activities in these dimensions are examined in more detail. The paper calls (1) for a more visible initiative to employ space activities to tackle urgent questions of global change and development, and (2) for a stronger impetus to secure European economic position in space sector as a key industry of the 21st century.

  10. Our leadership in science and technology as provided by the national space program

    Kock, W. E.

    1972-01-01

    The contributions of science and technology to the success of the United States as a world leader are discussed. Specific instances of the manner in which science advances and new technologies resulting from space research have contributed to a higher standard of living are presented. It is concluded that the benefits of the space program are not reflected only in the material advancements, but that intangible results have also been achieved in greater incentives to improve the present culture.

  11. Contagious architecture: computation, aesthetics, and space (technologies of lived abstraction)

    Parisi, Luciana

    2013-01-01

    In Contagious Architecture, Luciana Parisi offers a philosophical inquiry into the status of the algorithm in architectural and interaction design. Her thesis is that algorithmic computation is not simply an abstract mathematical tool but constitutes a mode of thought in its own right, in that its operation extends into forms of abstraction that lie beyond direct human cognition and control. These include modes of infinity, contingency, and indeterminacy, as well as incomputable quantities underlying the iterative process of algorithmic processing. The main philosophical source for the project is Alfred North Whitehead, whose process philosophy is specifically designed to provide a vocabulary for "modes of thought" exhibiting various degrees of autonomy from human agency even as they are mobilized by it. Because algorithmic processing lies at the heart of the design practices now reshaping our world -- from the physical spaces of our built environment to the networked spaces of digital culture -- the nature o...

  12. Recent technology products from Space Human Factors research

    Jenkins, James P.

    1991-01-01

    The goals of the NASA Space Human Factors program and the research carried out concerning human factors are discussed with emphasis given to the development of human performance models, data, and tools. The major products from this program are described, which include the Laser Anthropometric Mapping System; a model of the human body for evaluating the kinematics and dynamics of human motion and strength in microgravity environment; an operational experience data base for verifying and validating the data repository of manned space flights; the Operational Experience Database Taxonomy; and a human-computer interaction laboratory whose products are the display softaware and requirements and the guideline documents and standards for applications on human-computer interaction. Special attention is given to the 'Convoltron', a prototype version of a signal processor for synthesizing the head-related transfer functions.

  13. A percolation model of innovation in complex technology spaces

    Silverberg, G.; Verspagen, B.

    2002-01-01

    Innovations are known to arrive more highly clustered than if they were purely random, and their rate of arrival has been increasing nearly exponentially for several centuries. Their distribution of importance is highly skewed and appears to obey a power law or lognormal distribution. Technological

  14. Using New Technologies in Support of Future Space Missions

    Hooke, Adrian J.; Welch, David C.

    1997-01-01

    This paper forms a perspective of how new technologies such as onboard autonomy and internet-like protocols will change the look and feel of operations. It analyzes the concept of a lights-out mission operations control center and it's role in future mission support and it describes likely scenarios for evolving from current concepts.

  15. Management as the enabling technology for space exploration

    Mandell, Humboldt C., Jr.; Griffin, Michael D.

    1992-01-01

    This paper addresses the dilemma which NASA faces in starting a major new initiative within the constraints of the current national budget. It addressed the fact that unlike previous NASA programs, the major mission constraints come from management factors as opposed to technologies. An action plan is presented, along with some results from early management simplification processes.

  16. Brushless dc motors. [applications in non-space technology

    1975-01-01

    Brushless dc motors were intensively developed and tested over several years before qualification as the prime movers for Apollo Spacecraft life support blowers, and for circulating oxygen in the lunar portable life support system. Knowledge gained through prototype development and critical testing has significantly influenced the technology employed, broadened markets and applications, and reduced the cost of present day motors.

  17. Water Reclamation Technology Development at Johnson Space Center

    Callahan, Michael R.; Pickering, Karen

    2014-01-01

    Who We Are: A staff of approximately 14 BS, MS, and PhD-Level Engineers and Scientists with experience in Aerospace, Civil, Environmental, and Mechanical Engineering, Chemistry, Physical Science and Water Pollution Microbiology. Our Primary Objective: To develop the next generation water recovery system technologies that will support NASA's long duration missions beyond low-earth orbit.

  18. Mesh Networking in the Tactical Environment Using White Space Technolog

    2015-12-01

    facilitate the establishment of a point to multi-point network topology . The base station node handles the compilation of data necessary to determine a...the client nodes from the base station node, the number of client nodes, and the network topology . The metrics chosen for evaluation were picked as a...model, are commonly utilized to simulate quadratic path loss across free space [22]. This model uses the following formula to calculate path loss: L

  19. Goddard Technology Efforts to Improve Space Borne Laser Reliability

    Heaps, William S.

    2006-01-01

    In an effort to reduce the risk, perceived and actual, of employing instruments containing space borne lasers NASA initiated the Laser Risk Reduction Program (LRRP) in 2001. This program managed jointly by NASA Langley and NASA Goddard and employing lasers researchers from government, university and industrial labs is nearing the conclusion of its planned 5 year duration. This paper will describe some of the efforts and results obtained by the Goddard half of the program.

  20. Space power technology for the twenty-first century (SPT21)

    Borger, W.U.; Massie, L.D.

    1988-01-01

    During the spring and summer months of 1987, the Aero Propulsion Laboratory of the Air Force Wright Aeronautical Laboratories, Wright-Patterson AFB, Ohio in cooperation with the Air Force Space Technology Center at Kirtland AFB, New Mexico, undertook an initiative to develop a Strategic Plan for Space Power Technology Development. The initiative was called SPT21, Space Power Technology for the Twenty-First Century. The planning process involved the participation of other Government organizations (U.S. Army, Navy, DOE and NASA) along with major aerospace companies and universities. Following an SPT21 kickoff meeting on 28 May 1987, detailed strategic planning was accomplished through seven (7) Space Power Technology Discipline Workshops commencing in June 1987 and concluding in August 1987. Technology Discipline Workshops were conducted in the following areas: (1) Solar Thermal Dynamic Power Systems (2) Solar Photovoltaic Cells and Arrays (3) Thermal Management Technology (4) Energy Storage Technology (5) Nuclear Power Systems Technology (6) Power Conditioning, Distribution and Control and (7) Systems Technology/Advanced Concepts. This technical paper summarizes the planning process and describes the salient findings and conclusions of the workshops

  1. Technology Needs of Future Space Infrastructures Supporting Human Exploration and Development of Space

    Carrington, Connie; Howell, Joe

    2001-01-01

    The path to human presence beyond near-Earth will be paved by the development of infrastructure. A fundamental technology in this infrastructure is energy, which enables not only the basic function of providing shelter for man and machine, but also enables transportation, scientific endeavors, and exploration. This paper discusses the near-term needs in technology that develop the infrastructure for HEDS.

  2. Space Solar Power Technology Demonstration for Lunar Polar Applications: Laser-Photovoltaic Wireless Power Transmission

    Henley, M. W.; Fikes, J. C.; Howell, J.; Mankins, J. C.; Howell, Joe T. (Technical Monitor)

    2002-01-01

    Space Solar Power technology offers unique benefits for near-term NASA space science missions, which can mature this technology for other future applications. "Laser-Photo-Voltaic Wireless Power Transmission" (Laser-PV WPT) is a technology that uses a laser to beam power to a photovoltaic receiver, which converts the laser's light into electricity. Future Laser-PV WPT systems may beam power from Earth to satellites or large Space Solar Power satellites may beam power to Earth, perhaps supplementing terrestrial solar photo-voltaic receivers. In a near-term scientific mission to the moon, Laser-PV WPT can enable robotic operations in permanently shadowed lunar polar craters, which may contain ice. Ground-based technology demonstrations are proceeding, to mature the technology for this initial application, in the moon's polar regions.

  3. Research and Technology at the John F. Kennedy Space Center 1993

    1993-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1993 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities. Major areas of research include material science, advanced software, industrial engineering, nondestructive evaluation, life sciences, atmospheric sciences, environmental technology, robotics, and electronics and instrumentation.

  4. Space Solar Power Satellite Technology Development at the Glenn Research Center: An Overview

    Dudenhoefer, James E.; George, Patrick J.

    2000-01-01

    NASA Glenn Research Center (GRC). is participating in the Space Solar Power Exploratory Research and Technology program (SERT) for the development of a solar power satellite concept. The aim of the program is to provide electrical power to Earth by converting the Sun's energy and beaming it to the surface. This paper will give an overall view of the technologies being pursued at GRC including thin film photovoltaics, solar dynamic power systems, space environmental effects, power management and distribution, and electric propulsion. The developmental path not only provides solutions to gigawatt sized space power systems for the future, but provides synergistic opportunities for contemporary space power architectures. More details of Space Solar Power can be found by reading the references sited in this paper and by connecting to the web site http://moonbase.msfc.nasa.gov/ and accessing the "Space Solar Power" section "Public Access" area.

  5. Space situational awareness satellites and ground based radiation counting and imaging detector technology

    Jansen, Frank; Behrens, Joerg; Pospisil, Stanislav; Kudela, Karel

    2011-01-01

    We review the current status from the scientific and technological point of view of solar energetic particles, solar and galactic cosmic ray measurements as well as high energy UV-, X- and gamma-ray imaging of the Sun. These particles and electromagnetic data are an important tool for space situational awareness (SSA) aspects like space weather storm predictions to avoid failures in space, air and ground based technological systems. Real time data acquisition, position and energy sensitive imaging are demanded by the international space weather forecast services. We present how newly developed, highly miniaturized radiation detectors can find application in space in view of future SSA related satellites as a novel space application due to their counting and imaging capabilities.

  6. Space situational awareness satellites and ground based radiation counting and imaging detector technology

    Jansen, Frank, E-mail: frank.jansen@dlr.de [DLR Institute of Space Systems, Robert-Hooke-Str. 7, 28359 Bremen (Germany); Behrens, Joerg [DLR Institute of Space Systems, Robert-Hooke-Str. 7, 28359 Bremen (Germany); Pospisil, Stanislav [Czech Technical University, IEAP, 12800 Prague 2, Horska 3a/22 (Czech Republic); Kudela, Karel [Slovak Academy of Sciences, IEP, 04001 Kosice, Watsonova 47 (Slovakia)

    2011-05-15

    We review the current status from the scientific and technological point of view of solar energetic particles, solar and galactic cosmic ray measurements as well as high energy UV-, X- and gamma-ray imaging of the Sun. These particles and electromagnetic data are an important tool for space situational awareness (SSA) aspects like space weather storm predictions to avoid failures in space, air and ground based technological systems. Real time data acquisition, position and energy sensitive imaging are demanded by the international space weather forecast services. We present how newly developed, highly miniaturized radiation detectors can find application in space in view of future SSA related satellites as a novel space application due to their counting and imaging capabilities.

  7. Making Breakthroughs in the Turbulent Decade: China's Space Technology During the Cultural Revolution.

    Li, Chengzhi; Zhang, Dehui; Hu, Danian

    2017-09-01

    This article discusses why Chinese space programs were able to develop to the extent they did during the turbulent decade of the Cultural Revolution (1966-1976). It first introduces briefly what China had accomplished in rocket and missile technology before the Cultural Revolution, including the establishment of a system for research and manufacturing, breakthroughs in rocket technology, and programs for future development. It then analyzes the harmful impacts of the Cultural Revolution on Chinese space programs by examining activities of contemporary mass factions in the Seventh Ministry of Machinery Industry. In the third section, this article presents the important developments of Chinese space programs during the Cultural Revolution and explores briefly the significance of these developments for the future and overall progress in space technology. Finally, it discusses the reasons for the series of developments of Chinese space technology during the Cultural Revolution. This article concludes that, although the Cultural Revolution generated certain harmful impacts on the development of Chinese space technology, the Chinese essentially accomplished their scheduled objectives in their space program, both because of the great support of top Chinese leaders, including the officially disgraced Lin Biao and the Gang of Four, and due to the implementation of many effective special measures. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Progress update of NASA's free-piston Stirling space power converter technology project

    Dudenhoefer, James E.; Winter, Jerry M.; Alger, Donald

    1992-01-01

    A progress update is presented of the NASA LeRC Free-Piston Stirling Space Power Converter Technology Project. This work is being conducted under NASA's Civil Space Technology Initiative (CSTI). The goal of the CSTI High Capacity Power Element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA space initiatives. Efforts are focused upon increasing system power output and system thermal and electric energy conversion efficiency at least five fold over current SP-100 technology, and on achieving systems that are compatible with space nuclear reactors. This paper will discuss progress toward 1050 K Stirling Space Power Converters. Fabrication is nearly completed for the 1050 K Component Test Power Converter (CTPC); results of motoring tests of the cold end (525 K), are presented. The success of these and future designs is dependent upon supporting research and technology efforts including heat pipes, bearings, superalloy joining technologies, high efficiency alternators, life and reliability testing, and predictive methodologies. This paper will compare progress in significant areas of component development from the start of the program with the Space Power Development Engine (SPDE) to the present work on CTPC.

  9. "A Really Nice Spot": Evaluating Place, Space, and Technology in Academic Libraries

    Khoo, Michael J.; Rozaklis, Lily; Hall, Catherine; Kusunoki, Diana

    2016-01-01

    This article describes a qualitative mixed-method study of students' perceptions of place and space in an academic library. The approach is informed by Scott Bennett's model of library design, which posits a shift from a "book-centered" to a technology supported "learning centered" paradigm of library space. Two surveys…

  10. The Cube and the Poppy Flower: Participatory Approaches for Designing Technology-Enhanced Learning Spaces

    Casanova, Diogo; Mitchell, Paul

    2017-01-01

    This paper presents an alternative method for learning space design that is driven by user input. An exploratory study was undertaken at an English university with the aim of redesigning technology-enhanced learning spaces. Two provocative concepts were presented through participatory design workshops during which students and teachers reflected…

  11. Technology development for laser-cooled clocks on the International Space Station

    Klipstein, W. M.

    2003-01-01

    The PARCS experiment will use a laser-cooled cesium atomic clock operating in the microgravity environment aboard the International Space Station to provide both advanced tests of gravitational theory to demonstrate a new cold-atom clock technology for space.

  12. The 1995 Goddard Conference on Space Applications of Artificial Intelligence and Emerging Information Technologies

    Hostetter, Carl F. (Editor)

    1995-01-01

    This publication comprises the papers presented at the 1995 Goddard Conference on Space Applications of Artificial Intelligence and Emerging Information Technologies held at the NASA/Goddard Space Flight Center, Greenbelt, Maryland, on May 9-11, 1995. The purpose of this annual conference is to provide a forum in which current research and development directed at space applications of artificial intelligence can be presented and discussed.

  13. Improved Biosensors for Soils

    Silberg, J. J.; Masiello, C. A.; Cheng, H. Y.

    2014-12-01

    Microbes drive processes in the Earth system far exceeding their physical scale, affecting crop yields, water quality, the mobilization of toxic materials, and fundamental aspects of soil biogeochemistry. The tools of synthetic biology have the potential to significantly improve our understanding of microbial Earth system processes: for example, synthetic microbes can be be programmed to report on environmental conditions that stimulate greenhouse gas production, metal oxidation, biofilm formation, pollutant degradation, and microbe-plant symbioses. However, these tools are only rarely deployed in the lab. This research gap arises because synthetically programmed microbes typically report on their environment by producing molecules that are detected optically (e.g., fluorescent proteins). Fluorescent reporters are ideal for petri-dish applications and have fundamentally changed how we study human health, but their usefulness is quite limited in soils where detecting fluorescence is challenging. Here we describe the construction of gas-reporting biosensors, which release nonpolar gases that can be detected in the headspace of incubation experiments. These constructs can be used to probe microbial processes within soils in real-time noninvasive lab experiments. These biosensors can be combined with traditional omics-based approaches to reveal processes controlling soil microbial behavior and lead to improved environmental management decisions.

  14. The Role of Venezuelan Space Technology in Promoting Development in Latin America

    Pena, J. A.; Yumin, T.

    2017-09-01

    Space technology and resources are used around the world to address societal challenges. Space provides valuable satellite services, unique scientific discoveries, surprising technology applications and new economic opportunities. Venezuela formally recognizes the advantages of space resources and pursues national level activity to harness them. Venezuela space cooperation has grown in the past several years, contributing to debates over Venezuela's rising influence in the Latin America. This paper summarizes the establishment and current development of space activities in the Bolivarian Republic of Venezuela, these activities are focused on the areas of telecommunications, Earth observation, research and development space and has as a primary goal the satisfaction of social needs. This analysis offers the elements most important of the Venezuelan space policy: technological transfer, capacity building and human training and international cooperation including the new participation of Venezuela in the international charter on space and major disasters. Our analysis shows that Venezuela has the potential to become a space leadership country, promoting the social welfare, integration, and sustainable development of Latin American countries.

  15. THE ROLE OF VENEZUELAN SPACE TECHNOLOGY IN PROMOTING DEVELOPMENT IN LATIN AMERICA

    J. A. Pena

    2017-09-01

    Full Text Available Space technology and resources are used around the world to address societal challenges. Space provides valuable satellite services, unique scientific discoveries, surprising technology applications and new economic opportunities. Venezuela formally recognizes the advantages of space resources and pursues national level activity to harness them. Venezuela space cooperation has grown in the past several years, contributing to debates over Venezuela’s rising influence in the Latin America. This paper summarizes the establishment and current development of space activities in the Bolivarian Republic of Venezuela, these activities are focused on the areas of telecommunications, Earth observation, research and development space and has as a primary goal the satisfaction of social needs. This analysis offers the elements most important of the Venezuelan space policy: technological transfer, capacity building and human training and international cooperation including the new participation of Venezuela in the international charter on space and major disasters. Our analysis shows that Venezuela has the potential to become a space leadership country, promoting the social welfare, integration, and sustainable development of Latin American countries.

  16. Tin Oxide Nanorod Array-Based Electrochemical Hydrogen Peroxide Biosensor

    Liu Jinping

    2010-01-01

    Full Text Available Abstract SnO2 nanorod array grown directly on alloy substrate has been employed as the working electrode of H2O2 biosensor. Single-crystalline SnO2 nanorods provide not only low isoelectric point and enough void spaces for facile horseradish peroxidase (HRP immobilization but also numerous conductive channels for electron transport to and from current collector; thus, leading to direct electrochemistry of HRP. The nanorod array-based biosensor demonstrates high H2O2 sensing performance in terms of excellent sensitivity (379 μA mM−1 cm−2, low detection limit (0.2 μM and high selectivity with the apparent Michaelis–Menten constant estimated to be as small as 33.9 μM. Our work further demonstrates the advantages of ordered array architecture in electrochemical device application and sheds light on the construction of other high-performance enzymatic biosensors.

  17. A Review on Passive and Integrated Near-Field Microwave Biosensors

    Guha, Subhajit; Jamal, Farabi Ibne

    2017-01-01

    In this paper we review the advancement of passive and integrated microwave biosensors. The interaction of microwave with biological material is discussed in this paper. Passive microwave biosensors are microwave structures, which are fabricated on a substrate and are used for sensing biological materials. On the other hand, integrated biosensors are microwave structures fabricated in standard semiconductor technology platform (CMOS or BiCMOS). The CMOS or BiCMOS sensor technology offers a more compact sensing approach which has the potential in the future for point of care testing systems. Various applications of the passive and the integrated sensors have been discussed in this review paper. PMID:28946617

  18. Technology Estimating: A Process to Determine the Cost and Schedule of Space Technology Research and Development

    Cole, Stuart K.; Reeves, John D.; Williams-Byrd, Julie A.; Greenberg, Marc; Comstock, Doug; Olds, John R.; Wallace, Jon; DePasquale, Dominic; Schaffer, Mark

    2013-01-01

    NASA is investing in new technologies that include 14 primary technology roadmap areas, and aeronautics. Understanding the cost for research and development of these technologies and the time it takes to increase the maturity of the technology is important to the support of the ongoing and future NASA missions. Overall, technology estimating may help provide guidance to technology investment strategies to help improve evaluation of technology affordability, and aid in decision support. The research provides a summary of the framework development of a Technology Estimating process where four technology roadmap areas were selected to be studied. The framework includes definition of terms, discussion for narrowing the focus from 14 NASA Technology Roadmap areas to four, and further refinement to include technologies, TRL range of 2 to 6. Included in this paper is a discussion to address the evaluation of 20 unique technology parameters that were initially identified, evaluated and then subsequently reduced for use in characterizing these technologies. A discussion of data acquisition effort and criteria established for data quality are provided. The findings obtained during the research included gaps identified, and a description of a spreadsheet-based estimating tool initiated as a part of the Technology Estimating process.

  19. The role of Spaces and Occasions in the Transformation of Information Technologies

    Clausen, Christian; Koch, Christian

    1999-01-01

    The article adopts the view that technological change is a social process involving negotiations of a network of players. It aims at informing management of technology by identifying occasions and spaces where IT can be adressed and changed. the focus is on Enterprise Resource Planning systems....

  20. Synthetic Biology as an Enabling Technology for Space Exploration

    Rothschild, Lynn J.

    2016-01-01

    Human exploration off planet is severely limited by the cost of launching materials into space and by re-supply. Thus materials brought from Earth must be light, stable and reliable at destination. Using traditional approaches, a lunar or Mars base would require either transporting a hefty store of metals or heavy manufacturing equipment and construction materials for in situ extraction; both would severely limit any other mission objectives. Long-term human space presence requires periodic replenishment, adding a massive cost overhead. Even robotic missions often sacrifice science goals for heavy radiation and thermal protection. Biology has the potential to solve these problems because life can replicate and repair itself, and perform a wide variety of chemical reactions including making food, fuel and materials. Synthetic biology enhances and expands life's evolved repertoire. Using organisms as feedstock, additive manufacturing through bioprinting will make possible the dream of producing bespoke tools, food, smart fabrics and even replacement organs on demand. This new approach and the resulting novel products will enable human exploration and settlement on Mars, while providing new manufacturing approaches for life on Earth.

  1. New calorimeters for space experiments: physics requirements and technological challenges

    Marrocchesi, Pier Simone

    2015-07-01

    Direct measurements of charged cosmic radiation with instruments in Low Earth Orbit (LEO), or flying on balloons above the atmosphere, require the identification of the incident particle, the measurement of its energy and possibly the determination of its sign-of-charge. The latter information can be provided by a magnetic spectrometer together with a measurement of momentum. However, magnetic deflection in space experiments is at present limited to values of the Maximum Detectable Rigidity (MDR) hardly exceeding a few TV. Advanced calorimetric techniques are, at present, the only way to measure charged and neutral radiation at higher energies in the multi-TeV range. Despite their mass limitation, calorimeters may achieve a large geometric factor and provide an adequate proton background rejection factor, taking advantage of a fine granularity and imaging capabilities. In this lecture, after a brief introduction on electromagnetic and hadronic calorimetry, an innovative approach to the design of a space-borne, large acceptance, homogeneous calorimeter for the detection of high energy cosmic rays will be described.

  2. Automation and robotics for the Space Station - The influence of the Advanced Technology Advisory Committee

    Nunamaker, Robert R.; Willshire, Kelli F.

    1988-01-01

    The reports of a committee established by Congress to identify specific systems of the Space Station which would advance automation and robotics technologies are reviewed. The history of the committee, its relation to NASA, and the reports which it has released are discussed. The committee's reports recommend the widespread use of automation and robotics for the Space Station, a program for technology development and transfer between industries and research and development communities, and the planned use of robots to service and repair satellites and their payloads which are accessible from the Space Station.

  3. Last Advances in Silicon-Based Optical Biosensors

    Adrián Fernández Gavela

    2016-02-01

    Full Text Available We review the most important achievements published in the last five years in the field of silicon-based optical biosensors. We focus specially on label-free optical biosensors and their implementation into lab-on-a-chip platforms, with an emphasis on developments demonstrating the capability of the devices for real bioanalytical applications. We report on novel transducers and materials, improvements of existing transducers, new and improved biofunctionalization procedures as well as the prospects for near future commercialization of these technologies.

  4. Definition of technology development missions for early space station satellite servicing, volume 2

    1983-01-01

    The results of all aspects of the early space station satellite servicing study tasks are presented. These results include identification of servicing tasks (and locations), identification of servicing mission system and detailed objectives, functional/operational requirements analyses of multiple servicing scenarios, assessment of critical servicing technology capabilities and development of an evolutionary capability plan, design and validation of selected servicing technology development missions (TDMs), identification of space station satellite servicing accommodation needs, and the cost and schedule implications of acquiring both required technology capability development and conducting the selected TDMs.

  5. Maturing CCD Photon-Counting Technology for Space Flight

    Mallik, Udayan; Lyon, Richard; Petrone, Peter; McElwain, Michael; Benford, Dominic; Clampin, Mark; Hicks, Brian

    2015-01-01

    This paper discusses charge blooming and starlight saturation - two potential technical problems - when using an Electron Multiplying Charge Coupled Device (EMCCD) type detector in a high-contrast instrument for imaging exoplanets. These problems especially affect an interferometric type coronagraph - coronagraphs that do not use a mask to physically block starlight in the science channel of the instrument. These problems are presented using images taken with a commercial Princeton Instrument EMCCD camera in the Goddard Space Flight Center's (GSFC), Interferometric Coronagraph facility. In addition, this paper discusses techniques to overcome such problems. This paper also discusses the development and architecture of a Field Programmable Gate Array and Digital-to-Analog Converter based shaped clock controller for a photon-counting EMCCD camera. The discussion contained here will inform high-contrast imaging groups in their work with EMCCD detectors.

  6. A Study of Thermal Performance of Contemporary Technology-Rich Educational Spaces

    Sarah Elmasry

    2013-08-01

    Full Text Available One of the most dominant features of a classroom space is its high occupancy, which results in high internal heat gain (approximately 5 KW. Furthermore, installation of educational technologies, such as smart boards, projectors and computers in the spaces increases potential internal heat gain. Previous studies on office buildings indicate that with the introduction of IT equipment in spaces during the last decade, cooling load demands are increasing with an associated increase in summer electrical demand. Due to the fact that educational technologies in specific correspond to pedagogical practices within the space, a lot of variations due to occupancy patterns occur. Also, thermal loads caused by educational technologies are expected to be dependent on spatial configuration, for example, position with respect to the external walls, lighting equipment, mobility of devices. This study explores the thermal impact of educational technologies in 2 typical educational spaces in a facility of higher education; the classroom and the computer lab. The results indicate that a heat gain ranging between 0.06 and 0.095 KWh/m2 is generated in the rooms when educational technologies are in use. The second phase of this study is ongoing, and investigates thermal zones within the rooms due to distribution of educational technologies. Through simulation of thermal performance of the rooms, alternative room configurations are thus recommended in response to the observed thermal zones.

  7. Miniaturization of components and systems for space using MEMS-technology

    Grönland, Tor-Arne; Rangsten, Pelle; Nese, Martin; Lang, Martin

    2007-06-01

    Development of MEMS-based (micro electro mechanical system) components and subsystems for space applications has been pursued by various research groups and organizations around the world for at least two decades. The main driver for developing MEMS-based components for space is the miniaturization that can be achieved. Miniaturization can not only save orders of magnitude in mass and volume of individual components, but it can also allow increased redundancy, and enable novel spacecraft designs and mission scenarios. However, the commercial breakthrough of MEMS has not occurred within the space business as it has within other branches such as the IT/telecom or automotive industries, or as it has in biotech or life science applications. A main explanation to this is the highly conservative attitude to new technology within the space community. This conservatism is in many senses motivated by a very low risk acceptance in the few and costly space projects that actually ends with a space flight. To overcome this threshold there is a strong need for flight opportunities where reasonable risks can be accepted. Currently there are a few flight opportunities allowing extensive use of new technology in space, but one of the exceptions is the PRISMA program. PRISMA is an international (Sweden, Germany, France, Denmark, Norway, Greece) technology demonstration program with focus on rendezvous and formation flying. It is a two satellite LEO mission with a launch scheduled for the first half of 2009. On PRISMA, a number of novel technologies e.g. RF metrology sensor for Darwin, autonomous formation flying based on GPS and vision-based sensors, ADN-based "green propulsion" will be demonstrated in space for the first time. One of the satellites will also have a miniaturized propulsion system onboard based on MEMS-technology. This novel propulsion system includes two microthruster modules, each including four thrusters with micro- to milli-Newton thrust capability. The novelty

  8. Biosensors based on β-galactosidase enzyme: Recent advances and perspectives.

    Sharma, Shiv K; Leblanc, Roger M

    2017-10-15

    Many industries are striving for the development of more reliable and robust β-galactosidase biosensors that exhibit high response rate, increased detection limit and enriched useful lifetime. In a newfangled technological atmosphere, a trivial advantage or disadvantage of the developed biosensor may escort to the survival and extinction of the industry. Several alternative strategies to immobilize β-galactosidase enzyme for their utilization in biosensors have been developed in recent years in the quest of maximum utility by controlling the defects seen in the previous biosensors. The overwhelming call for on-line measurement of different sample constituents has directed science and industry to search for best practical solutions and biosensors are witnessed as the best prospect. The main objective of this paper is to serve as a narrow footbridge by comparing the literary works on the β-galactosidase biosensors, critically analyze their use in the construction of best biosensor by showing the pros and cons of the predicted methods for the practical use of biosensors. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. The place of space technology in economic development: Reflections on present and future aspects

    Lebeau, A.; Reuter, K. E.

    1980-01-01

    The effects of the development of satellite applications on the orientation of the space effort were examined. The gap between available and exploited technology, the impact of the current economic climate and future trends are discussed. Europe's low level of public funding for its space effort, in comparison to other space powers, and the dangers of complacency regarding Europe's competitiveness in the space market are illustrated. A proposal for the general direction which Europe's future strategy must take if European independence in this field is to be preserved is presented.

  10. Aerosol and cloud observations from the Lidar In-space Technology Experiment

    Winker, D. M.

    1995-01-01

    The Lidar In-Space Technology Experiment (LITE) is a backscatter lidar built by NASA Langley Research Center to fly on the Space Shuttle. The purpose of the program was to develop the engineering processes required for space lidar and to demonstrate applications of space lidar to remote sensing of the atmosphere. The instrument was flown on Discovery in September 1994. Global observations of clouds and aerosols were made between the latitudes of 57 deg N and 57 deg S during 10 days of the mission.

  11. Integrating Space Communication Network Capabilities via Web Portal Technologies

    Johnston, Mark D.; Lee, Carlyn-Ann; Lau, Chi-Wung; Cheung, Kar-Ming; Levesque, Michael; Carruth, Butch; Coffman, Adam; Wallace, Mike

    2014-01-01

    We have developed a service portal prototype as part of an investigation into the feasibility of using Java portlet technology as a means of providing integrated access to NASA communications network services. Portal servers provide an attractive platform for this role due to the various built-in collaboration applications they can provide, combined with the possibility to develop custom inter-operating portlets to extent their functionality while preserving common presentation and behavior. This paper describes various options for integration of network services related to planning and scheduling, and results based on use of a popular open-source portal framework. Plans are underway to develop an operational SCaN Service Portal, building on the experiences reported here.

  12. Active and Passive Technology Integration: A Novel Approach for Managing Technology's Influence on Learning Experiences in Context-Aware Learning Spaces

    Laine, Teemu H.; Nygren, Eeva

    2016-01-01

    Technology integration is the process of overcoming different barriers that hinder efficient utilisation of learning technologies. The authors divide technology integration into two components based on technology's role in the integration process. In active integration, the technology integrates learning resources into a learning space, making it…

  13. Detection Limits for Nanoscale Biosensors

    Sheehan, Paul E; Whitman, Lloyd J

    2005-01-01

    We examine through analytical calculations and finite element simulations how the detection efficiency of disk and wire-like biosensors in unmixed fluids varies with size from the micrometer to nanometer scales...

  14. Applying Space Technology to Enhance Control of an Artificial Arm

    Atkins, Diane; Donovan, William H.; Novy, Mara; Abramczyk, Robert

    1997-01-01

    At the present time, myoelectric prostheses perform only one function of the hand: open and close with the thumb, index and middle finger coming together to grasp various shaped objects. To better understand the limitations of the current single-function prostheses and the needs of the individuals who use them, The Institute for Rehabilitation and Research (TIRR), sponsored by the National Institutes of Health (August 1992 - November 1994), surveyed approximately 2500 individuals with upper limb loss. When asked to identify specific features of their current electric prosthesis that needed improvement, the survey respondents overwhelmingly identified the lack of wrist and finger movement as well as poor control capability. Simply building a mechanism with individual finger and wrist motion is not enough. Individuals with upper limb loss tend to reject prostheses that require continuous visual monitoring and concentration to control. Robotics researchers at NASA's Johnson Space Center (JSC) and Rice University have made substantial progress in myoelectric teleoperation. A myoelectric teleoperation system translates signals generated by an able-bodied robot operator's muscles during hand motions into commands that drive a robot's hand through identical motions. Farry's early work in myoelectric teleoperation used variations over time in the myoelectric spectrum as inputs to neural networks to discriminate grasp types and thumb motions. The resulting schemes yielded up to 93% correct classification on thumb motions. More recently, Fernandez achieved 100% correct non-realtime classification of thumb abduction, extension, and flexion on the same myoelectric data. Fernandez used genetic programming to develop functions that discriminate between thumb motions using myoelectric signal parameters. Genetic programming (GP) is an evolutionary programming method where the computer can modify the discriminating functions' form to improve its performance, not just adjust

  15. Recent Advances in Magnetic Microfluidic Biosensors

    Ioanna Giouroudi

    2017-07-01

    Full Text Available The development of portable biosening devices for the detection of biological entities such as biomolecules, pathogens, and cells has become extremely significant over the past years. Scientific research, driven by the promise for miniaturization and integration of complex laboratory equipment on inexpensive, reliable, and accurate devices, has successfully shifted several analytical and diagnostic methods to the submillimeter scale. The miniaturization process was made possible with the birth of microfluidics, a technology that could confine, manipulate, and mix very small volumes of liquids on devices integrated on standard silicon technology chips. Such devices are then directly translating the presence of these entities into an electronic signal that can be read out with a portable instrumentation. For the aforementioned tasks, the use of magnetic markers (magnetic particles—MPs—functionalized with ligands in combination with the application of magnetic fields is being strongly investigated by research groups worldwide. The greatest merits of using magnetic fields are that they can be applied either externally or from integrated microconductors and they can be well-tuned by adjusting the applied current on the microconductors. Moreover, the magnetic markers can be manipulated inside microfluidic channels by high gradient magnetic fields that can in turn be detected by magnetic sensors. All the above make this technology an ideal candidate for the development of such microfluidic biosensors. In this review, focus is given only to very recent advances in biosensors that use microfluidics in combination with magnetic sensors and magnetic markers/nanoparticles.

  16. Micro- and nanogap based biosensors

    Hammond, Jules L.

    2017-01-01

    Biosensors are used for the detection of a range of analytes for applications in healthcare, food production, environmental monitoring and biodefence. However, many biosensing platforms are large, expensive, require skilled operators or necessitate the analyte to be labelled. Direct electrochemical detection methods present a particularly attractive platform due to the simplified instrumentation when compared to other techniques such as fluorescence-based biosensors. With modern integrated ci...

  17. Recycling microcavity optical biosensors.

    Hunt, Heather K; Armani, Andrea M

    2011-04-01

    Optical biosensors have tremendous potential for commercial applications in medical diagnostics, environmental monitoring, and food safety evaluation. In these applications, sensor reuse is desirable to reduce costs. To achieve this, harsh, wet chemistry treatments are required to remove surface chemistry from the sensor, typically resulting in reduced sensor performance and increased noise due to recognition moiety and optical transducer degradation. In the present work, we suggest an alternative, dry-chemistry method, based on O2 plasma treatment. This approach is compatible with typical fabrication of substrate-based optical transducers. This treatment completely removes the recognition moiety, allowing the transducer surface to be refreshed with new recognition elements and thus enabling the sensor to be recycled.

  18. DNA nanotechnology-enabled biosensors.

    Chao, Jie; Zhu, Dan; Zhang, Yinan; Wang, Lianhui; Fan, Chunhai

    2016-02-15

    Biosensors employ biological molecules to recognize the target and utilize output elements which can translate the biorecognition event into electrical, optical or mass-sensitive signals to determine the quantities of the target. DNA-based biosensors, as a sub-field to biosensor, utilize DNA strands with short oligonucleotides as probes for target recognition. Although DNA-based biosensors have offered a promising alternative for fast, simple and cheap detection of target molecules, there still exist key challenges including poor stability and reproducibility that hinder their competition with the current gold standard for DNA assays. By exploiting the self-recognition properties of DNA molecules, researchers have dedicated to make versatile DNA nanostructures in a highly rigid, controllable and functionalized manner, which offers unprecedented opportunities for developing DNA-based biosensors. In this review, we will briefly introduce the recent advances on design and fabrication of static and dynamic DNA nanostructures, and summarize their applications for fabrication and functionalization of DNA-based biosensors. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Cryogenic Propellant Storage and Transfer Technology Demonstration For Long Duration In-Space Missions

    Meyer, Michael L.; Motil, Susan M.; Kortes, Trudy F.; Taylor, William J.; McRight, Patrick S.

    2012-01-01

    The high specific impulse of cryogenic propellants can provide a significant performance advantage for in-space transfer vehicles. The upper stages of the Saturn V and various commercial expendable launch vehicles have used liquid oxygen and liquid hydrogen propellants; however, the application of cryogenic propellants has been limited to relatively short duration missions due to the propensity of cryogens to absorb environmental heat resulting in fluid losses. Utilizing advanced cryogenic propellant technologies can enable the efficient use of high performance propellants for long duration missions. Crewed mission architectures for beyond low Earth orbit exploration can significantly benefit from this capability by developing realistic launch spacing for multiple launch missions, by prepositioning stages and by staging propellants at an in-space depot. The National Aeronautics and Space Administration through the Office of the Chief Technologist is formulating a Cryogenic Propellant Storage and Transfer Technology Demonstration Mission to mitigate the technical and programmatic risks of infusing these advanced technologies into the development of future cryogenic propellant stages or in-space propellant depots. NASA is seeking an innovative path for human space exploration, which strengthens the capability to extend human and robotic presence throughout the solar system. This mission will test and validate key cryogenic technological capabilities and has the objectives of demonstrating advanced thermal control technologies to minimize propellant loss during loiter, demonstrating robust operation in a microgravity environment, and demonstrating efficient propellant transfer on orbit. The status of the demonstration mission concept development, technology demonstration planning and technology maturation activities in preparation for flight system development are described.

  20. Use of Space Technology in Flood Mitigation (Western Province, Zambia)

    Mulando, A.

    2001-05-01

    Disasters, by definition are events that appear suddenly and with little warning. They are usually short lived, with extreme events bringing death, injury and destruction of buildings and communications. Their aftermath can be as damaging as their physical effects through destruction of sanitation and water supplies, destruction of housing and breakdown of transport for food, temporary shelter and emergency services. Since floods are one of the natural disasters which endanger both life and property, it becomes vital to know its extents and where the hazards exists. Flood disasters manifest natural processes on a larger scale and information provided by Remote Sensing is a most appropriate input to analysis of actual events and investigations of potential risks. An analytical and qualitative image processing and interpretation of Remotely Sensed data as well as other data such as rainfall, population, settlements not to mention but a few should be used to derive good mitigation strategies. Since mitigation is the cornerstone of emergency management, it therefore becomes a sustained action that will reduce or eliminate long term risks to people and property from natural hazards such as floods and their effects. This will definitely involve keeping of homes and other sensitive structures away from flood plains. Promotion of sound land use planning based on this known hazard, "FLOODS" is one such form of mitigation that can be applied in flood affected areas within flood plain. Therefore future mitigation technologies and procedures should increasingly be based on the use of flood extent information provided by Remote Sensing Satellites like the NOAA AVHRR as well as information on the designated flood hazard and risk areas.

  1. Teaching with Space: K-6 Aviation, Space and Technology Resource Guide

    1998-01-01

    Teaching with Space permits easy and quick identification of resources you will find most beneficial. This guide captures the essence of resources with applicability across the elementary curriculum. Specific product reviews and suggested uses in the classroom are provided to enable informed decision-making. Materials from NASA and the Federal Aviation Administration may be obtained in limited quantities at no cost from public domain sources when available. Pricing in this guide is based on duplication, warehousing, and overhead costs associated with distributing these items. Although this resource guide is a prototype guide distributed on a limited basis, we trust you will find it useful in locating quality instructional resources. Your suggestions and comments are most welcome, and will receive the fullest consideration as we work to expand and validate this guide for national distribution. Based on teacher criteria for quality, educational soundness, compatibility with the curriculum, ease of use, and affordability, the guide will be updated as new resources become available, and in response to teacher feedback. You may provide us with additional items for consideration at any time. We also are planning to develop a resource guide for middle and high school teachers, and your input is welcome for that effort too. This guide is just one way that space can help you in the classroom.

  2. Environmental Control and Life Support Systems technology options for Space Station application

    Hall, J. B., Jr.; Ferebee, M. J., Jr.; Sage, K. H.

    1985-01-01

    Continuous assessments regarding the suitability of candidate technologies for manned Space Stations will be needed over the next several years to obtain a basis for recommending the optimum system for an Initial Operating Capability (IOC) Space Station which is to be launched in the early 1990's. This paper has the objective to present analysis programs, the candidate recommendations, and the recommended approach for integration these candidates into the NASA Space Station reference configuration. Attention is given to ECLSS (Environmental Control and Life Support System) technology assessment program, an analysis approach for candidate technology recommendations, mission model variables, a candidate integration program, metabolic oxygen recovery, urine/flush water and all waste water recovery, wash water and condensate water recovery, and an integration analysis.

  3. Overview of free-piston Stirling engine technology for space power application

    Slaby, J.G.

    1987-01-01

    An overview is presented of the National Aeronautics and Space Administration (NASA) Lewis Research Center (LeRC) free-piston Stirling engine activities directed toward space-power application. Free-piston Stirling technology is applicable for both solar and nuclear powered systems. As such, the NASA Lewis Research Center serves as the project office to manage the newly initiated SP-100 Advanced Technology program. This program provides the technology push for providing significant component and subsystem options for increased efficiency, reliability and survivability, and power output growth at reduced specific mass. One of the major elements of the program is the development of advanced power conversion of which the Stirling cycle is a viable candidate. Under this program the status of the 25 kWe opposed-piston Space Power Demonstrator Engine (SPDE) is presented. Included in the SPDE discussion are initial differences between predicted and experimental power outputs and power output influenced by variations in regenerators

  4. Lunar base mission technology issues and orbital demonstration requirements on space station

    Llewellyn, Charles P.; Weidman, Deene J.

    1992-01-01

    The International Space Station has been the object of considerable design, redesign, and alteration since it was originally proposed in early 1984. In the intervening years the station has slowly evolved to a specific design that was thoroughly reviewed by a large agency-wide Critical Evaluation Task Force (CETF). As space station designs continue to evolve, studies must be conducted to determine the suitability of the current design for some of the primary purposes for which the station will be used. This paper concentrates on the technology requirements and issues, the on-orbit demonstration and verification program, and the space station focused support required prior to the establishment of a permanently manned lunar base as identified in the National Commission on Space report. Technology issues associated with the on-orbit assembly and processing of the lunar vehicle flight elements are also discussed.

  5. Proceedings of the 12th Space Photovoltaic Research and Technology Conference (SPRAT 12)

    1993-01-01

    The Twelfth Space Photovoltaic Research and Technology conference was held at the NASA Lewis Research Center from 20 to 22 Oct. 1992. The papers and workshops presented in this volume report substantial progress in a variety of areas in space photovoltaics. Topics covered include: high efficiency GaAs and InP solar cells, GaAs/Ge cells as commercial items, flexible amorphous and thin film solar cells (in the early stages of pilot production), high efficiency multiple bandgap cells, laser power converters, solar cell and array technology, heteroepitaxial cells, betavoltaic energy conversion, and space radiation effects in InP cells. Space flight data on a variety of cells were also presented.

  6. Regional Centres for Space Science and Technology Education Affiliated to the United Nations

    Aquino, A. J. A.; Haubold, H. J.

    2010-05-01

    Based on resolutions of the United Nations General Assembly, Regional Centres for space science and technology education were established in India, Morocco, Nigeria, Brazil and Mexico. Simultaneously, education curricula were developed for the core disciplines of remote sensing, satellite communications, satellite meteorology, and space and atmospheric science. This paper provides a brief report on the status of the operation of the Regional Centres and draws attention to their educational activities.

  7. Prospective areas in the production technology of scientific equipment for space research

    Breslavets, A. V.

    1974-01-01

    The average labor of individual types of operations in the percentage ratio of the total labor consumption of manufacturing scientific instruments and apparatus for space research is presented. The prospective areas in the production technology of billet, machining, mechanical assembly, installation and assembly, adjustment and regulation and testing and control operations are noted. Basic recommendations are made with respect to further reduction of labor consumption and an increase in the productivity of labor when manufacturing scientific equipment for space research.

  8. Integrated Atmosphere Resource Recovery and Environmental Monitoring Technology Demonstration for Deep Space Exploration

    Perry, Jay L.; Abney, Morgan B.; Knox, James C.; Parrish, Keith J.; Roman, Monserrate C.; Jan, Darrell L.

    2012-01-01

    Exploring the frontiers of deep space continues to be defined by the technological challenges presented by safely transporting a crew to and from destinations of scientific interest. Living and working on that frontier requires highly reliable and efficient life support systems that employ robust, proven process technologies. The International Space Station (ISS), including its environmental control and life support (ECLS) system, is the platform from which humanity's deep space exploration missions begin. The ISS ECLS system Atmosphere Revitalization (AR) subsystem and environmental monitoring (EM) technical architecture aboard the ISS is evaluated as the starting basis for a developmental effort being conducted by the National Aeronautics and Space Administration (NASA) via the Advanced Exploration Systems (AES) Atmosphere Resource Recovery and Environmental Monitoring (ARREM) Project.. An evolutionary approach is employed by the ARREM project to address the strengths and weaknesses of the ISS AR subsystem and EM equipment, core technologies, and operational approaches to reduce developmental risk, improve functional reliability, and lower lifecycle costs of an ISS-derived subsystem architecture suitable for use for crewed deep space exploration missions. The most promising technical approaches to an ISS-derived subsystem design architecture that incorporates promising core process technology upgrades will be matured through a series of integrated tests and architectural trade studies encompassing expected exploration mission requirements and constraints.

  9. Advancing automation and robotics technology for the space station and for the US economy

    Nunamaker, Robert

    1988-01-01

    In April 1985, as required by Public Law 98-371, the NASA Advanced Technology Advisory Committee (ATAC) reported to Congress the results of its studies on advanced automation and robotics technology for use on the Space Station. This material was documented in the initial report (NASA Technical Memo 87566). A further requirement of the law was that ATAC follow NASA's progress in this area and report to Congress semiannually. This report is the sixth in a series of progress updates and covers the period between October 1, 1987 and March 1, 1988. NASA has accepted the basic recommendations of ATAC for its Space Station efforts. ATAC and NASA agree that the thrust of Congress is to build an advanced automation and robotics technology base that will support an evolutionary Space Station program and serve as a highly visible stimulator affecting the U.S. long-term economy. The progress report identifies the work of NASA and the Space Station study contractors, research in progress, and issues connected with the advancement of automation and robotics technology on the Space Station.

  10. NANOSCALE BIOSENSORS IN ECOSYSTEM EXPOSURE RESEARCH

    This powerpoint presentation presented information on nanoscale biosensors in ecosystem exposure research. The outline of the presentation is as follows: nanomaterials environmental exposure research; US agencies involved in nanosensor research; nanoscale LEDs in biosensors; nano...

  11. BIOSENSORS FOR ENVIRONMENTAL MONITORING: A REGULATORY PERSPECTIVE

    Biosensors show the potential to complement laboratory-based analytical methods for environmental applications. Although biosensors for potential environmental-monitoring applications have been reported for a wide range of environmental pollutants, from a regulatory perspective, ...

  12. Space Communications and Data Systems Technologies for Next Generation Earth Science Measurements

    Bauer, Robert A.; Reinhart, Richard C.; Hilderman, Don R.; Paulsen, Phillip E.

    2003-01-01

    The next generation of Earth observing satellites and sensor networks will face challenges in supporting robust high rate communications links from the increasingly sophisticated onboard instruments. Emerging applications will need data rates forecast to be in the 100's to 1000's of Mbps. As mission designers seek smaller spacecraft, challenges exist in reducing the size and power requirements while increasing the capacity of the spacecraft's communications technologies. To meet these challenges, this work looks at three areas of selected space communications and data services technologies, specifically in the development of reflectarray antennas, demonstration of space Internet concepts, and measurement of atmospheric propagation effects on Ka-band signal transmitted from LEO.

  13. Portable Diagnostics Technology Assessment for Space Missions. Part 2; Market Survey

    Nelson, Emily S.; Chait, Arnon

    2010-01-01

    A mission to Mars of several years duration requires more demanding standards for all onboard instruments than a 6-month mission to the Moon or the International Space Station. In Part 1, we evaluated generic technologies and suitability to NASA needs. This prior work considered crew safety, device maturity and flightworthiness, resource consumption, and medical value. In Part 2, we continue the study by assessing the current marketplace for reliable Point-of-Care diagnostics. The ultimate goal of this project is to provide a set of objective analytical tools to suggest efficient strategies for reaching specific medical targets for any given space mission as program needs, technological development, and scientific understanding evolve.

  14. Exploration Space Suit Architecture and Destination Environmental-Based Technology Development

    Hill, Terry R.; McFarland, Shane M.; Korona, F. Adam

    2013-01-01

    This paper continues forward where EVA Space Suit Architecture: Low Earth Orbit Vs. Moon Vs. Mars left off in the development of a space suit architecture that is modular in design and could be reconfigured prior to launch or during any given mission depending on the tasks or destination. This space suit system architecture and technologies required based on human exploration (EVA) destinations will be discussed, and how these systems should evolve to meet the future exploration EVA needs of the US human space flight program. A series of exercises and analyses provided a strong indication that the Constellation Program space suit architecture, with its maximum reuse of technology and functionality across a range of mission profiles and destinations, is postured to provide a viable solution for future space exploration missions. The destination environmental analysis demonstrates that the modular architecture approach could provide the lowest mass and mission cost for the protection of the crew, given any human mission outside of low-Earth orbit. Additionally, some of the high-level trades presented here provide a review of the environmental and nonenvironmental design drivers that will become increasingly important as humans venture farther from Earth. The presentation of destination environmental data demonstrates a logical clustering of destination design environments that allows a focused approach to technology prioritization, development, and design that will maximize the return on investment, largely independent of any particular design reference mission.

  15. Overview of NASA's Space Solar Power Technology Advanced Research and Development Program

    Howell, Joe; Mankins, John C.; Davis, N. Jan (Technical Monitor)

    2001-01-01

    Large solar power satellite (SPS) systems that might provide base load power into terrestrial markets were examined extensively in the 1970s by the US Department of Energy (DOE) and the National Aeronautics and Space Administration (NASA). Following a hiatus of about 15 years, the subject of space solar power (SSP) was reexamined by NASA from 1995-1997 in the 'fresh look' study, and during 1998 in an SSP 'concept definition study', and during 1999-2000 in the SSP Exploratory Research and Technology (SERT) program. As a result of these efforts, during 2001, NASA has initiated the SSP Technology Advanced Research and Development (STAR-Dev) program based on informed decisions. The goal of the STAR-Dev program is to conduct preliminary strategic technology research and development to enable large, multi-megawatt to gigawatt-class space solar power (SSP) systems and wireless power transmission (WPT) for government missions and commercial markets (in-space and terrestrial). Specific objectives include: (1) Release a NASA Research Announcement (NRA) for SSP Projects; (2) Conduct systems studies; (3) Develop Component Technologies; (4) Develop Ground and Flight demonstration systems; and (5) Assess and/or Initiate Partnerships. Accomplishing these objectives will allow informed future decisions regarding further SSP and related research and development investments by both NASA management and prospective external partners. In particular, accomplishing these objectives will also guide further definition of SSP and related technology roadmaps including performance objectives, resources and schedules; including 'multi-purpose' applications (commercial, science, and other government).

  16. Cost-Effective Additive Manufacturing in Space: HELIOS Technology Challenge Guide

    DeVieneni, Alayna; Velez, Carlos Andres; Benjamin, David; Hollenbeck, Jay

    2012-01-01

    Welcome to the HELIOS Technology Challenge Guide. This document is intended to serve as a general road map for participants of the HELIOS Technology Challenge [HTC] Program and the associated inaugural challenge: HTC-01: Cost-Effective Additive Manufacturing in Space. Please note that this guide is not a rule book and is not meant to hinder the development of innovative ideas. Its primary goal is to highlight the objectives of the HTC-01 Challenge and to describe possible solution routes and pitfalls that such technology may encounter in space. Please also note that participants wishing to demonstrate any hardware developed under this program during any future HELIOS Technology Challenge showcase event(s) may be subject to event regulations to be published separately at a later date.

  17. NASA advanced space photovoltaic technology-status, potential and future mission applications

    Flood, Dennis J.; Piszczor, Michael, Jr.; Stella, Paul M.; Bennett, Gary L.

    1989-01-01

    The NASA program in space photovoltaic research and development encompasses a wide range of emerging options for future space power systems, and includes both cell and array technology development. The long range goals are to develop technology capable of achieving 300 W/kg for planar arrays, and 300 W/sq m for concentrator arrays. InP and GaAs planar and concentrator cell technologies are under investigation for their potential high efficiency and good radiation resistance. The Advanced Photovoltaic Solar Array (APSA) program is a near term effort aimed at demonstrating 130 W/kg beginning of life specific power using thin (62 micrometer) silicon cells. It is intended to be technology transparent to future high efficiency cells and provides the baseline for development of the 300 W/kg array.

  18. Infrared and submillimeter space missions in the coming decade programmes, programmatics, and technology

    Sauvage, Marc; Gallais, Pascal; Vigroux, Laurent

    1996-01-01

    A revolution similar to that brought by CCDs to visible astronomy is still ahead in IR and submillimeter astronomy. There is certainly no wavelength range which has, over the past several years, seen such impressive advances in technology: large-scale detector arrays, new designs for cooling in space, lightweight mirror technologies. Scientific cases for observing the cold universe are outstanding. Observations in the FIR/Submm range will provide answers to such fundamental questions as: What is the spectrum of the primordial fluctuations? How do primeval galaxies look? What are the first stages of star formation? Most of the international space missions that have been triggered by these questions are presented in detail here. Technological issues raised by these missions are reviewed, as are the most recent achievements in cooling and detector technologies.

  19. Development of Electrochemical Biosensors for Ultrasensitive Detection of Bacteria in the Environment

    Fapyane, Deby

    2018-01-01

    to those conventional methods, are intensively studied. Biosensor technology is one of the strategies for rapid monitoring of pathogens such as bacteria, virus, and parasites in the environment. Among them, the electrochemical biosensor offers simple, rapid, cost-effective and possibility...... for ultrasensitive detection of bacterial cells, DNA and rRNA. Several key operational parameters were assessed such as the optimization of probe design and labeling molecules. Here, more specifically we used two novel labels for the development of the electrochemical biosensor for bacteria detection; cellulase...

  20. ECLSS Integration Analysis: Advanced ECLSS Subsystem and Instrumentation Technology Study for the Space Exploration Initiative

    1990-01-01

    In his July 1989 space policy speech, President Bush proposed a long range continuing commitment to space exploration and development. Included in his goals were the establishment of permanent lunar and Mars habitats and the development of extended duration space transportation. In both cases, a major issue is the availability of qualified sensor technologies for use in real-time monitoring and control of integrated physical/chemical/biological (p/c/b) Environmental Control and Life Support Systems (ECLSS). The purpose of this study is to determine the most promising instrumentation technologies for future ECLSS applications. The study approach is as follows: 1. Precursor ECLSS Subsystem Technology Trade Study - A database of existing and advanced Atmosphere Revitalization (AR) and Water Recovery and Management (WRM) ECLSS subsystem technologies was created. A trade study was performed to recommend AR and WRM subsystem technologies for future lunar and Mars mission scenarios. The purpose of this trade study was to begin defining future ECLSS instrumentation requirements as a precursor to determining the instrumentation technologies that will be applicable to future ECLS systems. 2. Instrumentation Survey - An instrumentation database of Chemical, Microbial, Conductivity, Humidity, Flowrate, Pressure, and Temperature sensors was created. Each page of the sensor database report contains information for one type of sensor, including a description of the operating principles, specifications, and the reference(s) from which the information was obtained. This section includes a cursory look at the history of instrumentation on U.S. spacecraft. 3. Results and Recommendations - Instrumentation technologies were recommended for further research and optimization based on a consideration of both of the above sections. A sensor or monitor technology was recommended based on its applicability to future ECLS systems, as defined by the ECLSS Trade Study (1), and on whether its

  1. Alkaline water electrolysis technology for Space Station regenerative fuel cell energy storage

    Schubert, F. H.; Hoberecht, M. A.; Le, M.

    1986-01-01

    The regenerative fuel cell system (RFCS), designed for application to the Space Station energy storage system, is based on state-of-the-art alkaline electrolyte technology and incorporates a dedicated fuel cell system (FCS) and water electrolysis subsystem (WES). In the present study, emphasis is placed on the WES portion of the RFCS. To ensure RFCS availability for the Space Station, the RFCS Space Station Prototype design was undertaken which included a 46-cell 0.93 cu m static feed water electrolysis module and three integrated mechanical components.

  2. Novel Space-based Solar Power Technologies and Architectures for Earth and Beyond

    Howell, Joe T.; Fikes, John C.; O'Neill, Mark J.

    2005-01-01

    Research, development and studies of novel space-based solar power systems, technologies and architectures for Earth and beyond are needed to reduce the cost of clean electrical power for terrestrial use and to provide a stepping stone for providing an abundance of power in space, i.e., manufacturing facilities, tourist facilities, delivery of power between objects in space, and between space and surface sites. The architectures, technologies and systems needed for space to Earth applications may also be used for in-space applications. Advances in key technologies, i.e., power generation, power management and distribution, power beaming and conversion of beamed power are needed to achieve the objectives of both terrestrial and extraterrestrial applications. Power beaming or wireless power transmission (WPT) can involve lasers or microwaves along with the associated power interfaces. Microwave and laser transmission techniques have been studied with several promising approaches to safe and efficient WPT identified. These investigations have included microwave phased array transmitters, as well as laser transmission and associated optics. There is a need to produce "proof-of-concept" validation of critical WPT technologies for both the near-term, as well as far-term applications. Investments may be harvested in near-term beam safe demonstrations of commercial WPT applications. Receiving sites (users) include ground-based stations for terrestrial electrical power, orbital sites to provide power for satellites and other platforms, future space elevator systems, space vehicle propulsion, and space to surface sites. This paper briefly discusses achieving a promising approach to the solar power generation and beamed power conversion. The approach is based on a unique high-power solar concentrator array called Stretched Lens Array (SLA) for both solar power generation and beamed power conversion. Since both versions (solar and laser) of SLA use many identical components

  3. Internet Technologies for Space-based Communications: State of the Art and Challenges

    Bhasin, K.; DePaula, R.; Edwards, C.

    2000-01-01

    The Internet is rapidly changing the ways we communicate information around the globe today. The desire to provide Internet-based services to anyone, anywhere, anytime has brought satellite communications to the forefront to become an integral part of the Internet. In spite of the distances involved, satellite links are proving to be capable of providing Internet services based on Internet protocol (TCP/IP) stack. This development has led to the question particularly at NASA; can satellites and other space platforms become an Internet-node in space? This will allow the direct transfer of information directly from space to the users on Earth and even be able to control the spacecraft and its instruments. NASA even wants to extend the near earth space Internet to deep space applications where scientists and the public here on Earth may view space exploration in real time via the Internet. NASA's future solar system exploration will involve intensive in situ investigations of planets, moons, asteroids, and comets. While past missions typically involved a single fly-by or orbiting science spacecraft, future missions will begin to use fleets of small, highly intelligent robotic vehicles to carry out collaborative investigations. The resulting multi-spacecraft topologies will effectively create a wide area network spanning the solar system. However, this will require significant development in Internet technologies for space use. This paper provides the status'of the Internet for near earth applications and the potential extension of the Internet for use in deep space planetary exploration. The paper will discuss the overall challenges of implementing the space Internet and how the space Internet will integrate into the complex terrestrial systems those forms the Internet of today in a hybrid set of networks. Internet. We envision extending to the deep space environment such Internet concepts as a well-designed layered architecture. This effort will require an ability to

  4. Features and application of wearable biosensors in medical care

    Sima Ajami

    2015-01-01

    Full Text Available One of the new technologies in the field of health is wearable biosensor, which provides vital signs monitoring of patients, athletes, premature infants, children, psychiatric patients, people who need long-term care, elderly, and people in impassable regions far from health and medical services. The aim of this study was to explain features and applications of wearable biosensors in medical services. This was a narrative review study that done in 2015. Search conducted with the help of libraries, books, conference proceedings, through databases of Science Direct, PubMed, Proquest, Springer, and SID (Scientific Information Database. In our searches, we employed the following keywords and their combinations; vital sign monitoring, medical smart shirt, smart clothing, wearable biosensors, physiological monitoring system, remote detection systems, remote control health, and bio-monitoring system. The preliminary search resulted in 54 articles, which published between 2002 and 2015. After a careful analysis of the content of each paper, 41 sources selected based on their relevancy. Although the use of wearable in healthcare is still in an infant stage, it could have a magic effect on healthcare. Smart wearable in the technology industry for 2015 is one that is looking to be a big and profitable market. Wearable biosensors capable of continuous vital signs monitoring and feedback to the user will be significantly effective in timely prevention, diagnosis, treatment, and control of diseases.

  5. The space telescope: A study of NASA, science, technology, and politics

    Smith, Robert William

    1989-01-01

    Scientific, technological, economic, and political aspects of NASA efforts to orbit a large astronomical telescope are examined in a critical historical review based on extensive interviews with participants and analysis of published and unpublished sources. The scientific advantages of large space telescopes are explained; early plans for space observatories are summarized; the history of NASA and its major programs is surveyed; the redesign of the original Large Space Telescope for Shuttle deployability is discussed; the impact of the yearly funding negotiations with Congress on the development of the final Hubble Space Telescope (HST) is described; and the implications of the HST story for the future of large space science projects are explored. Drawings, photographs, a description of the HST instruments and systems, and lists of the major contractors and institutions participating in the HST program are provided.

  6. The use of a cubesat to validate technological bricks in space

    Rakotonimbahy, E.; Vives, S.; Dohlen, K.; Savini, G.; Iafolla, V.

    2017-11-01

    In the framework of the FP7 program FISICA (Far Infrared Space Interferometer Critical Assessment), we are developing a cubesat platform which will be used for the validation in space of two technological bricks relevant for FIRI. The first brick is a high-precision accelerometer which could be used in a future space mission as fundamental element for the dynamic control loop of the interferometer. The second brick is a miniaturized version of an imaging multi-aperture telescope. Ultimately, such an instrument could be composed of numerous space-born mirror segments flying in precise formation on baselines of hundreds or thousands of meters, providing high-resolution glimpses of distant worlds. We are proposing to build a very first space-born demonstrator of such an instrument which will fit into the limited resources of one cubesat. In this paper, we will describe the detailed design of the cubesat hosting the two payloads.

  7. Definition of technology development missions for early Space Station satellite servicing. Volume 1: Executive summary

    1984-01-01

    The Executive Summary volume 1, includes an overview of both phases of the Definition of Technology Development Missions for Early Space Station Satellite Servicing. The primary purpose of Phase 1 of the Marshall Space Flight Center (MSFC) Satellite Servicing Phase 1 study was to establish requirements for demonstrating the capability of performing satellite servicing activities on a permanently manned Space Station in the early 1990s. The scope of Phase 1 included TDM definition, outlining of servicing objectives, derivation of initial Space Station servicing support requirements, and generation of the associated programmatic schedules and cost. The purpose of phase 2 of the satellite servicing study was to expand and refine the overall understanding of how best to use the manned space station as a test bed for demonstration of satellite servicing capabilities.

  8. Space technology, sustainable development and community applications: Internet as a facilitator

    Peter, Nicolas; Afrin, Nadia; Goh, Gérardine; Chester, Ed

    2006-07-01

    Among other approaches, space technologies are currently being deployed for disaster management, environmental monitoring, urban planning, health applications, communications, etc. Although space-based applications have tremendous potential for socioeconomic development, they are primarily technology driven and the requirements from the end-users (i.e. the development community) are rarely taken into consideration during the initial development stages. This communication gap between the "space" and "development" communities can be bridged with the help of the web-based knowledge sharing portal focused on space applications for development. This online community uses the development gateway foundation's sophisticated content management system. It is modeled after the development gateway's knowledge sharing portals ( http://topics.developmentgateway.org) and draws from their expertise in knowledge management, partnership building and marketing. These types of portal are known to facilitate broad-based partnerships across sectors, regions and the various stakeholders but also to facilitate North-South and South-South cooperation. This paper describes the initiative "Space for Development" ( http://topics.developmentgateway.org/space) started in 2004 which aims to demonstrate how such a web-based portal can be structured to facilitate knowledge sharing in order to bridge the gap between the "space" and "development" communities in an innovative and global manner.

  9. The NASA In-Space Propulsion Technology Project, Products, and Mission Applicability

    Anderson, David J.; Pencil, Eric; Liou, Larry; Dankanich, John; Munk, Michelle M.; Kremic, Tibor

    2009-01-01

    The In-Space Propulsion Technology (ISPT) Project, funded by NASA s Science Mission Directorate (SMD), is continuing to invest in propulsion technologies that will enable or enhance NASA robotic science missions. This overview provides development status, near-term mission benefits, applicability, and availability of in-space propulsion technologies in the areas of aerocapture, electric propulsion, advanced chemical thrusters, and systems analysis tools. Aerocapture investments improved: guidance, navigation, and control models of blunt-body rigid aeroshells; atmospheric models for Earth, Titan, Mars, and Venus; and models for aerothermal effects. Investments in electric propulsion technologies focused on completing NASA s Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6 to 7 kW throttle-able gridded ion system. The project is also concluding its High Voltage Hall Accelerator (HiVHAC) mid-term product specifically designed for a low-cost electric propulsion option. The primary chemical propulsion investment is on the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance for lower cost. The project is also delivering products to assist technology infusion and quantify mission applicability and benefits through mission analysis and tools. In-space propulsion technologies are applicable, and potentially enabling for flagship destinations currently under evaluation, as well as having broad applicability to future Discovery and New Frontiers mission solicitations.

  10. Advances in space power research and technology at the National Aeronautics and Space Administration

    Mullin, J. P.; Randolph, L. P.; Hudson, W. R.; Ambrus, J. H.

    1981-01-01

    Progress and plans in various areas of the NASA Space Power Program are discussed. Solar cell research is narrowed to GaAs, multibandgap, and thin Si cells for arrays in planar and concentrator configurations, with further work to increase cell efficiency, radiation hardness, develop flexible encapsulants, and reduce cost. Electrochemical research is concentrating on increasing energy and power density, cycle and wet stand life, reliability and cost reduction of batteries. Further development of the Ni-H2 battery and O2-H2 fuel cell to multihundred kW with a 5 year life and 30,000 cycles is noted. Basic research is ongoing for alkali metal anodes for high energy density secondary cells. Nuclear thermoelectric propulsion is being developed for outer planets exploration propulsion systems, using Si-Ge generators, and studies with rare earth chalcogenides and sulfides are mentioned. Power Systems Management seeks to harmonize increasing power supply levels with inner and outer spacecraft environments, circuits, demands, and automatic monitoring. Concomitant development of bipolar transistors, an infrared rectenna, spacecraft charging measurement, and larger heat pipe transport capacity are noted.

  11. Advances in space power research and technology at the National Aeronautics and Space Administration

    Mullin, J.P.; Randolph, L.P.; Hudson, W.R.; Ambrus, J.H.

    1981-01-01

    Progress and plans in various areas of the NASA Space Power Program are discussed. Solar cell research is narrowed to GaAs, multibandgap, and thin Si cells for arrays in planar and concentrator configurations, with further work to increase cell efficiency, radiation hardness, develop flexible encapsulants, and reduce cost. Electrochemical research is concentrating on increasing energy and power density, cycle and wet stand life, reliability and cost reduction of batteries. Further development of the Ni-H 2 battery and O 2 -H 2 fuel cell to multihundred kW with a 5 year life and 30,000 cycles is noted. Basic research is ongoing for alkali metal anodes for high energy density secondary cells. Nuclear thermoelectric propulsion is being developed for outer planets exploration propulsion systems, using Si-Ge generators, and studies with rare earth chalcogenides and sulfides are mentioned. Power Systems Management seeks to harmonize increasing power supply levels with inner and outer spacecraft environments, circuits, demands, and automatic monitoring. Concomitant development of bipolar transistors, an infrared rectenna, spacecraft charging measurement, and larger heat pipe transport capacity are noted

  12. Biosensor for metal analysis and speciation

    Aiken, Abigail M.; Peyton, Brent M.; Apel, William A.; Petersen, James N.

    2007-01-30

    A biosensor for metal analysis and speciation is disclosed. The biosensor comprises an electron carrier immobilized to a surface of an electrode and a layer of an immobilized enzyme adjacent to the electrode. The immobilized enzyme comprises an enzyme having biological activity inhibited by a metal to be detected by the biosensor.

  13. Statement of Aaron Cohen, Director, Research and Engineering, Johnson Space Center and Chairman, Space Station Advanced Technology Advisory Committee, National Aeronautics and Space Administration, before the Subcommittee on Science, Technology, and Space, Committee on Commerce, Science, and Transportation, United States Senate

    Cohen, A.

    1985-01-01

    The activities of NASA's Space Station Advanced Technology Advisory Committee is discussed. Advanced Technology Advisory Committee (ATAC) activities over the last year are reviewed in preparation of the report to Congress on the potential for advancing automation and robotics technology for the space station and for the U.S. economy.

  14. Biosensors in Health Care: The Milestones Achieved in Their Development towards Lab-on-Chip-Analysis

    Suprava Patel

    2016-01-01

    Full Text Available Immense potentiality of biosensors in medical diagnostics has driven scientists in evolution of biosensor technologies and innovating newer tools in time. The cornerstone of the popularity of biosensors in sensing wide range of biomolecules in medical diagnostics is due to their simplicity in operation, higher sensitivity, ability to perform multiplex analysis, and capability to be integrated with different function by the same chip. There remains a huge challenge to meet the demands of performance and yield to its simplicity and affordability. Ultimate goal stands for providing point-of-care testing facility to the remote areas worldwide, particularly the developing countries. It entails continuous development in technology towards multiplexing ability, fabrication, and miniaturization of biosensor devices so that they can provide lab-on-chip-analysis systems to the community.

  15. Swamp Works: A New Approach to Develop Space Mining and Resource Extraction Technologies at the National Aeronautics Space Administration (NASA) Kennedy Space Center (KSC)

    Mueller, R. P.; Sibille, L.; Leucht, K.; Smith, J. D.; Townsend, I. I.; Nick, A. J.; Schuler, J. M.

    2015-01-01

    The first steps for In Situ Resource Utilization (ISRU) on target bodies such as the Moon, Mars and Near Earth Asteroids (NEA), and even comets, involve the same sequence of steps as in the terrestrial mining of resources. First exploration including prospecting must occur, and then the resource must be acquired through excavation methods if it is of value. Subsequently a load, haul and dump sequence of events occurs, followed by processing of the resource in an ISRU plant, to produce useful commodities. While these technologies and related supporting operations are mature in terrestrial applications, they will be different in space since the environment and indigenous materials are different than on Earth. In addition, the equipment must be highly automated, since for the majority of the production cycle time, there will be no humans present to assist or intervene. This space mining equipment must withstand a harsh environment which includes vacuum, radical temperature swing cycles, highly abrasive lofted dust, electrostatic effects, van der Waals forces effects, galactic cosmic radiation, solar particle events, high thermal gradients when spanning sunlight terminators, steep slopes into craters / lava tubes and cryogenic temperatures as low as 40 K in permanently shadowed regions. In addition the equipment must be tele-operated from Earth or a local base where the crew is sheltered. If the tele-operation occurs from Earth then significant communications latency effects mandate the use of autonomous control systems in the mining equipment. While this is an extremely challenging engineering design scenario, it is also an opportunity, since the technologies developed in this endeavor could be used in the next generations of terrestrial mining equipment, in order to mine deeper, safer, more economical and with a higher degree of flexibility. New space technologies could precipitate new mining solutions here on Earth. The NASA KSC Swamp Works is an innovation

  16. Microbial Monitoring from the Frontlines to Space: Department of Defense Small Business Innovation Research Technology Aboard the International Space Station

    Oubre, Cherie M.; Khodadad, Christina L.; Castro, Victoria A.; Ott, C. Mark; Flint, Stephanie; Pollack, Lawrence P.; Roman, Monserrate C.

    2017-01-01

    The RAZOR (trademark) EX, a quantitative Polymerase Chain Reaction (qPCR) instrument, is a portable, ruggedized unit that was designed for the Department of Defense (DoD) with its reagent chemistries traceable to a Small Business Innovation Research (SBIR) contract beginning in 2002. The PCR instrument's primary function post 9/11 was to enable frontline soldiers and first responders to detect biological threat agents and bioterrorism activities in remote locations to include field environments. With its success for DoD, the instrument has also been employed by other governmental agencies including Department of Homeland Security (DHS). The RAZOR (Trademark) EX underwent stringent testing by the vendor, as well as through the DoD, and was certified in 2005. In addition, the RAZOR (trademark) EX passed DHS security sponsored Stakeholder Panel on Agent Detection Assays (SPADA) rigorous evaluation in 2011. The identification and quantitation of microbial pathogens is necessary both on the ground as well as during spaceflight to maintain the health of astronauts and to prevent biofouling of equipment. Currently, culture-based monitoring technology has been adequate for short-term spaceflight missions but may not be robust enough to meet the requirements for long-duration missions. During a NASA-sponsored workshop in 2011, it was determined that the more traditional culture-based method should be replaced or supplemented with more robust technologies. NASA scientists began investigating innovative molecular technologies for future space exploration and as a result, PCR was recommended. Shortly after, NASA sponsored market research in 2012 to identify and review current, commercial, cutting edge PCR technologies for potential applicability to spaceflight operations. Scientists identified and extensively evaluated three candidate technologies with the potential to function in microgravity. After a thorough voice-of-the-customer trade study and extensive functional and

  17. Development of Space Life Supporting System Using Radiation Technology (Top Brand Project)

    Lee, Ju Woon; Kim, Jae Hun; Song, Beom Seok; Choi, Jong Il; Yoon, Yo Han; Park, Jin Kyu; Park, Jae Nam; Han, In Jun; Lee, Yoon Jong [KAERI, Daejeon (Korea, Republic of)

    2010-08-15

    To simulate the space environment of microgravity and expose to space radiation, Hindlimb Suspension Model was established in Gamma Phytotron. Hindlimb suspended group exposed to irradiation, non-suspended group not exposed to irradiation, and non-suspended group exposed to irradiation were experimented for 2 weeks at the dose rate of 3.2 mSV/day. The results showed that muscle weight was decreased by suspension. To develop the countermeasure to physiological changes in space environment, the peptides from soy beam was selected to evaluate the effect with the space environment simulation model. Suing the microscopic and fluorescent images, the growth of microorganisms were detected. The species were identified based on primer-targeted gene sequence analysis. Also, the radiation resistance of species was defined. To research on sustainable nutritional supply and improvement of human physiology in space environment, four kinds of new Korean space foods (Bulgogi, Bibimbap, Seaweed soup, and Mulberry beverage) were developed using the irradiation technology and certified as space foods by the Russian Institute of Biomedical Problems. The contract on joint research of MARS-500 between KAERI and IBMP was made. In the experiment, crews for expedition to Mars will eat Korean space foods (Bulgogi, Bibimbap, Seaweed soup, Mulberry beverage, Kimchi, Sujeonggwa) for 120 days, then their immunity will be examined and compared with it on the ground. The developed technology and know-how could be spun out to the various fields, such as aircraft, automobile, military, information and communication, bio technologies. Moreover, the results obtained from this research can be used for the further development for military use or special food area such as foods for patient

  18. Development of Space Life Supporting System Using Radiation Technology (Top Brand Project)

    Lee, Ju Woon; Kim, Jae Hun; Song, Beom Seok; Choi, Jong Il; Yoon, Yo Han; Park, Jin Kyu; Park, Jae Nam; Han, In Jun; Lee, Yoon Jong

    2010-08-01

    To simulate the space environment of microgravity and expose to space radiation, Hindlimb Suspension Model was established in Gamma Phytotron. Hindlimb suspended group exposed to irradiation, non-suspended group not exposed to irradiation, and non-suspended group exposed to irradiation were experimented for 2 weeks at the dose rate of 3.2 mSV/day. The results showed that muscle weight was decreased by suspension. To develop the countermeasure to physiological changes in space environment, the peptides from soy beam was selected to evaluate the effect with the space environment simulation model. Suing the microscopic and fluorescent images, the growth of microorganisms were detected. The species were identified based on primer-targeted gene sequence analysis. Also, the radiation resistance of species was defined. To research on sustainable nutritional supply and improvement of human physiology in space environment, four kinds of new Korean space foods (Bulgogi, Bibimbap, Seaweed soup, and Mulberry beverage) were developed using the irradiation technology and certified as space foods by the Russian Institute of Biomedical Problems. The contract on joint research of MARS-500 between KAERI and IBMP was made. In the experiment, crews for expedition to Mars will eat Korean space foods (Bulgogi, Bibimbap, Seaweed soup, Mulberry beverage, Kimchi, Sujeonggwa) for 120 days, then their immunity will be examined and compared with it on the ground. The developed technology and know-how could be spun out to the various fields, such as aircraft, automobile, military, information and communication, bio technologies. Moreover, the results obtained from this research can be used for the further development for military use or special food area such as foods for patient

  19. Impedimetric biosensors and immunosensors

    Prodromidis, M.I.

    2007-01-01

    The development of methods targeting the direct monitoring of antibody-antigen interactions is particularly attractive. The design of label-free affinity-based probing concepts is the objective of much current research, at both academic and industrial levels, towards establishing alternative methods to the already existing ELISA-based immunoassays. Among these, Electrochemical Impedance Spectroscopy (EIS) represents one of the most powerful methods, due to the ability of EIS-based sensors to be more easily integrated into multi-array or microprocessor, controlled diagnostic tools. During the last decade, EIS and the concept of biochemical capacitors have been widely used for probing various types of biomolecular interactions (immunosensors, DNA hybridization, protein-protein interactions). So far, impedimetric or capacitive immunosensors have been successfully applied at the academic level. However, no prototypes have been released into the market, since major fundamental issues still exist. Even though this fact has brought the reliability of impedimetric immunosensors into question, features associated with electrochemical approaches, namely the ability to be miniaturized, remote control of implanted sensors, low cost of electrode mass production and cost effective instrumentation (without need of high-energy sources) keep impedimetric sensors particularly attractive as compared to other approaches based on microbalances, surface plasmon resonance or ellipsometry. This lecture outlines the theoretical background of impedimetric immunosensors and presents different types of impedimetric biosensors as well as the instrumental approaches that have been so far proposed in the literature. (author)

  20. SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 3: Space power and thermal management

    1991-06-01

    Viewgraphs of briefings from the SSTAC/ARTS review of the draft integrated technology plan on thermal power and thermal management are presented. Topics covered include: space energy conversion research and technology; space photovoltaic energy conversion; chemical energy conversion and storage; thermal energy conversion; power management; thermal management; space nuclear power; high capacity power; surface power and thermal management; space platforms power and thermal management; and project SELENE

  1. Advanced UVOIR Mirror Technology Development (AMTD) for Very Large Space Telescopes

    Stahl, H. Philip; Smith, W. Scott; Mosier, Gary; Abplanalp, Laura; Arnold, William

    2014-01-01

    ASTRO2010 Decadal stated that an advanced large-aperture ultraviolet, optical, near-infrared (UVOIR) telescope is required to enable the next generation of compelling astrophysics and exoplanet science; and, that present technology is not mature enough to affordably build and launch any potential UVOIR mission concept. AMTD builds on the state of art (SOA) defined by over 30 years of monolithic & segmented ground & space-telescope mirror technology to mature six key technologies. AMTD is deliberately pursuing multiple design paths to provide the science community with op-tions to enable either large aperture monolithic or segmented mirrors with clear engineering metrics traceable to science requirements.

  2. Definition of common support equipment and space station interface requirements for IOC model technology experiments

    Russell, Richard A.; Waiss, Richard D.

    1988-01-01

    A study was conducted to identify the common support equipment and Space Station interface requirements for the IOC (initial operating capabilities) model technology experiments. In particular, each principal investigator for the proposed model technology experiment was contacted and visited for technical understanding and support for the generation of the detailed technical backup data required for completion of this study. Based on the data generated, a strong case can be made for a dedicated technology experiment command and control work station consisting of a command keyboard, cathode ray tube, data processing and storage, and an alert/annunciator panel located in the pressurized laboratory.

  3. Space technology in the discovery and development of mineral and energy resources

    Lowman, P. D.

    1977-01-01

    Space technology, applied to the discovery and extraction of mineral and energy resources, is summarized. Orbital remote sensing for geological purposes has been widely applied through the use of LANDSAT satellites. These techniques also have been of value for protection against environmental hazards and for a better understanding of crustal structure.

  4. The Space Technology-7 Disturbance Reduction System Precision Control Flight Validation Experiment Control System Design

    O'Donnell, James R.; Hsu, Oscar C.; Maghami, Peirman G.; Markley, F. Landis

    2006-01-01

    As originally proposed, the Space Technology-7 Disturbance Reduction System (DRS) project, managed out of the Jet Propulsion Laboratory, was designed to validate technologies required for future missions such as the Laser Interferometer Space Antenna (LISA). The two technologies to be demonstrated by DRS were Gravitational Reference Sensors (GRSs) and Colloidal MicroNewton Thrusters (CMNTs). Control algorithms being designed by the Dynamic Control System (DCS) team at the Goddard Space Flight Center would control the spacecraft so that it flew about a freely-floating GRS test mass, keeping it centered within its housing. For programmatic reasons, the GRSs were descoped from DRS. The primary goals of the new mission are to validate the performance of the CMNTs and to demonstrate precise spacecraft position control. DRS will fly as a part of the European Space Agency (ESA) LISA Pathfinder (LPF) spacecraft along with a similar ESA experiment, the LISA Technology Package (LTP). With no GRS, the DCS attitude and drag-free control systems make use of the sensor being developed by ESA as a part of the LTP. The control system is designed to maintain the spacecraft s position with respect to the test mass, to within 10 nm/the square root of Hz over the DRS science frequency band of 1 to 30 mHz.

  5. An assessment of advanced displays and controls technology applicable to future space transportation systems

    Hatfield, Jack J.; Villarreal, Diana

    1990-01-01

    The topic of advanced display and control technology is addressed along with the major objectives of this technology, the current state of the art, major accomplishments, research programs and facilities, future trends, technology issues, space transportation systems applications and projected technology readiness for those applications. The holes that may exist between the technology needs of the transportation systems versus the research that is currently under way are addressed, and cultural changes that might facilitate the incorporation of these advanced technologies into future space transportation systems are recommended. Some of the objectives are to reduce life cycle costs, improve reliability and fault tolerance, use of standards for the incorporation of advancing technology, and reduction of weight, volume and power. Pilot workload can be reduced and the pilot's situational awareness can be improved, which would result in improved flight safety and operating efficiency. This could be accomplished through the use of integrated, electronic pictorial displays, consolidated controls, artificial intelligence, and human centered automation tools. The Orbiter Glass Cockpit Display is an example examined.

  6. NASA Systems Autonomy Demonstration Project - Development of Space Station automation technology

    Bull, John S.; Brown, Richard; Friedland, Peter; Wong, Carla M.; Bates, William

    1987-01-01

    A 1984 Congressional expansion of the 1958 National Aeronautics and Space Act mandated that NASA conduct programs, as part of the Space Station program, which will yield the U.S. material benefits, particularly in the areas of advanced automation and robotics systems. Demonstration programs are scheduled for automated systems such as the thermal control, expert system coordination of Station subsystems, and automation of multiple subsystems. The programs focus the R&D efforts and provide a gateway for transfer of technology to industry. The NASA Office of Aeronautics and Space Technology is responsible for directing, funding and evaluating the Systems Autonomy Demonstration Project, which will include simulated interactions between novice personnel and astronauts and several automated, expert subsystems to explore the effectiveness of the man-machine interface being developed. Features and progress on the TEXSYS prototype thermal control system expert system are outlined.

  7. Electron Emitter for small-size Electrodynamic Space Tether using MEMS Technology

    Fleron, René A. W.; Blanke, Mogens

    2004-01-01

    Adjustment of the orbit of a spacecraft using the forces created by an electro-dynamic space-tether has been shown as a theoretic possibility in recent literature. Practical implementation is being pursued for larger scale missions where a hot filament device controls electron emission...... and the current flowing in the electrodynamic space tether. Applications to small spacecraft, or space debris in the 1–10 kg range, possess difficulties with electron emission technology, as low power emitting devices are needed. This paper addresses the system concepts of a small spacecraft electrodynamic tether...... system with focus on electron emitter design and manufacture using micro-electro-mechanical- system (MEMS) technology. The paper addresses the system concepts of a small size electrodynamic tether mission and shows a novel electron emitter for the 1-2 mA range where altitude can be effectively affected...

  8. A dual use case study of space technologies for terrestrial medical applications (Conference Presentation)

    Cozmuta, Ioana

    2017-05-01

    Many challenges exist in understanding the human body as a whole, its adaptability, its resilience, its immunological response, its healing and regeneration power. New knowledge is usually obtained by exploring unique conditions and environments and space is one such variable. Primarily, these attributes have been studied in space for the purpose of understanding the effect of the space environment on long duration space travel. However a myriad of lessons learned have emerged that are important for terrestrial medicine problems such as cardiovascular changes, intracranial pressure changes, vision changes, reduced immunity, etc. For medical study purposes, the changes induced by the space environment on the human body are in general fast and predictable; they persist while in the space environment but also revert to the initial pre-flight healthy state upon return to Earth. This provides a unique cycle to study wellness and disease prediction as well as to develop more effective countermeasures for the benefit of people on earth. At a scientific level, the environment of space can be used to develop new lines of investigations and new knowledge to push the terrestrial state of the art (i.e. study of phase diagrams, identification of new system's states, etc). Moreover, the specialized requirements for space medicine have driven advances in terrestrial medical technologies in areas such as monitoring, diagnostic, prevention and treatment. This talk will provide an overview of compelling examples in key areas of interest for terrestrial medical applications.

  9. Last results of technological developments for ultra-lightweight, large aperture, deployable mirror for space telescopes

    Gambicorti, Lisa; D'Amato, Francesco; Vettore, Christian; Duò, Fabrizio; Guercia, Alessio; Patauner, Christian; Biasi, Roberto; Lisi, Franco; Riccardi, Armando; Gallieni, Daniele; Lazzarini, Paolo; Tintori, Matteo; Zuccaro Marchi, Alessandro; Pereira do Carmo, Joao

    2017-11-01

    The aim of this work is to describe the latest results of new technological concepts for Large Aperture Telescopes Technology (LATT) using thin deployable lightweight active mirrors. This technology is developed under the European Space Agency (ESA) Technology Research Program and can be exploited in all the applications based on the use of primary mirrors of space telescopes with large aperture, segmented lightweight telescopes with wide Field of View (FOV) and low f/#, and LIDAR telescopes. The reference mission application is a potential future ESA mission, related to a space borne DIAL (Differential Absorption Lidar) instrument operating around 935.5 nm with the goal to measure water vapor profiles in atmosphere. An Optical BreadBoard (OBB) for LATT has been designed for investigating and testing two critical aspects of the technology: 1) control accuracy in the mirror surface shaping. 2) mirror survivability to launch. The aim is to evaluate the effective performances of the long stroke smart-actuators used for the mirror control and to demonstrate the effectiveness and the reliability of the electrostatic locking (EL) system to restraint the thin shell on the mirror backup structure during launch. The paper presents a comprehensive vision of the breadboard focusing on how the requirements have driven the design of the whole system and of the various subsystems. The manufacturing process of the thin shell is also presented.

  10. Photonic crystals: emerging biosensors and their promise for point-of-care applications.

    Inan, Hakan; Poyraz, Muhammet; Inci, Fatih; Lifson, Mark A; Baday, Murat; Cunningham, Brian T; Demirci, Utkan

    2017-01-23

    Biosensors are extensively employed for diagnosing a broad array of diseases and disorders in clinical settings worldwide. The implementation of biosensors at the point-of-care (POC), such as at primary clinics or the bedside, faces impediments because they may require highly trained personnel, have long assay times, large sizes, and high instrumental cost. Thus, there exists a need to develop inexpensive, reliable, user-friendly, and compact biosensing systems at the POC. Biosensors incorporated with photonic crystal (PC) structures hold promise to address many of the aforementioned challenges facing the development of new POC diagnostics. Currently, PC-based biosensors have been employed for detecting a variety of biotargets, such as cells, pathogens, proteins, antibodies, and nucleic acids, with high efficiency and selectivity. In this review, we provide a broad overview of PCs by explaining their structures, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-based biosensors incorporated with emerging technologies, including telemedicine, flexible and wearable sensing, smart materials and metamaterials. Finally, we discuss current challenges associated with existing biosensors, and provide an outlook for PC-based biosensors and their promise at the POC.

  11. Space Technology Game Changing Development- Next Generation Life Support: Spacecraft Oxygen Recovery (SCOR)

    Abney, Morgan; Barta, Daniel

    2015-01-01

    The Next Generation Life Support Spacecraft Oxygen Recovery (SCOR) project element is dedicated to developing technology that enables oxygen recovery from metabolically produced carbon dioxide in space habitats. The state-of-the-art system on the International Space Station uses Sabatier technology to recover (is) approximately 50% oxygen from carbon dioxide. The remaining oxygen required for crew respiration is supplied from Earth. For long duration manned missions beyond low-Earth orbit, resupply of oxygen becomes economically and logistically prohibitive. To mitigate these challenges, the SCOR project element is targeting development of technology to increase the recovery of oxygen to 75% or more, thereby reducing the total oxygen resupply required for future missions.

  12. Micro-and nanoelectromechanical biosensors

    Nicu, Liviu

    2014-01-01

    Most books dedicated to the issues of bio-sensing are organized by the well-known scheme of a biosensor. In this book, the authors have deliberately decided to break away from the conventional way of treating biosensing research by uniquely addressing biomolecule immobilization methods on a solid surface, fluidics issues and biosensing-related transduction techniques, rather than focusing simply on the biosensor. The aim is to provide a contemporary snapshot of the biosensing landscape without neglecting the seminal references or products where needed, following the downscaling (from the micr

  13. Tunable solid-state laser technology for applications to scientific and technological experiments from space

    Allario, F.; Taylor, L. V.

    1986-01-01

    Current plans for the Earth Observing System (EOS) include development of a lidar facility to conduct scientific experiments from a polar orbiting platforms. A recommended set of experiments were scoped, which includes techniques of atmospheric backscatter (Lidar), Differential Absorption Lidar (DIAL), altimetry, and retroranging. Preliminary assessments of the resources (power, weight, volume) required by the Eos Lidar Facility were conducted. A research program in tunable solid state laser technology was developed, which includes laser materials development, modeling and experiments on the physics of solid state laser materials, and development of solid state laser transmitters with a strong focus on Eos scientific investigations. Some of the system studies that were conducted which highlight the payoff of solid state laser technology for the Eos scientific investigations will be discussed. Additionally, a summary of some promising research results which have recently emerged from the research program will be presented.

  14. Innovations in biomedical nanoengineering: nanowell array biosensor

    Seo, YoungTae; Jeong, Sunil; Lee, JuKyung; Choi, Hak Soo; Kim, Jonghan; Lee, HeaYeon

    2018-04-01

    Nanostructured biosensors have pioneered biomedical engineering by providing highly sensitive analyses of biomolecules. The nanowell array (NWA)-based biosensing platform is particularly innovative, where the small size of NWs within the array permits extremely profound sensing of a small quantity of biomolecules. Undoubtedly, the NWA geometry of a gently-sloped vertical wall is critical for selective docking of specific proteins without capillary resistances, and nanoprocessing has contributed to the fabrication of NWA electrodes on gold substrate such as molding process, e-beam lithography, and krypton-fluoride (KrF) stepper semiconductor method. The Lee group at the Mara Nanotech has established this NW-based biosensing technology during the past two decades by engineering highly sensitive electrochemical sensors and providing a broad range of detection methods from large molecules (e.g., cells or proteins) to small molecules (e.g., DNA and RNA). Nanosized gold dots in the NWA enhance the detection of electrochemical biosensing to the range of zeptomoles in precision against the complementary target DNA molecules. In this review, we discuss recent innovations in biomedical nanoengineering with a specific focus on novel NWA-based biosensors. We also describe our continuous efforts in achieving a label-free detection without non-specific binding while maintaining the activity and stability of immobilized biomolecules. This research can lay the foundation of a new platform for biomedical nanoengineering systems.

  15. Interferometric optical fiber microcantilever beam biosensor

    Wavering, Thomas A.; Meller, Scott A.; Evans, Mishell K.; Pennington, Charles; Jones, Mark E.; VanTassell, Roger; Murphy, Kent A.; Velander, William H.; Valdes, E.

    2000-12-01

    With the proliferation of biological weapons, the outbreak of food poisoning occurrences, and the spread of antibiotic resistant strains of pathogenic bacteria, the demand has arisen for portable systems capable of rapid, specific, and quantitative target detection. The ability to detect minute quantities of targets will provide the means to quickly assess a health hazardous situation so that the appropriate response can be orchestrated. Conventional test results generally require hours or even several days to be reported, and there is no change for real-time feedback. An interferometric optical fiber microcantilever beam biosensor has successfully demonstrated real time detection of target molecules. The microcantilever biosensor effectively combines advanced technology from silicon micromachining, optical fiber sensor, and biochemistry to create a novel detection device. This approach utilizes affinity coatings on micromachiend cantilever beams to attract target molecules. The presence of the target molecule causes bending in the cantilever beam, which is monitored using an optical displacement system. Dose-response trials have shown measured responses at nanogram/ml concentrations of target molecules. Sensitivity is expected to extend from the nanogram to the picogram range of total captured mass as the microcantilever sensors are optimized.

  16. Diabetes mellitus: biosensors for research and management.

    Turner, A P; Pickup, J C

    1985-01-01

    The condition of diabetes mellitus is described with particular reference to the parameters that it would be desirable to monitor in order to improve management and understanding of the disease. Previous attention has largely focused on analysis of glucose, but many other intermediates of carbohydrate, fat and protein metabolism are deranged in diabetes and may be alternative measures of control. The need for laboratory analysers, self-monitoring, closed-loop devices and alarms are detailed and the problems associated with implantable sensors discussed. Progress in the development of biosensors is reviewed using glucose sensors as the main example. Electrochemical, optoelectronic and calorimetric approaches to sensing are considered and it is concluded that configurations based either on hydrogen peroxide detection or on mediated electron transfer are most likely to provide a raid route to in vivo monitoring. The extension of biosensor technology to tackle other important substrates is discussed, the principal hurdle to success being seen as the lack of long-term stability of the biological component.

  17. Biosensors in Clinical Practice: Focus on Oncohematology

    Agostino Cortelezzi

    2013-05-01

    Full Text Available Biosensors are devices that are capable of detecting specific biological analytes and converting their presence or concentration into some electrical, thermal, optical or other signal that can be easily analysed. The first biosensor was designed by Clark and Lyons in 1962 as a means of measuring glucose. Since then, much progress has been made and the applications of biosensors are today potentially boundless. This review is limited to their clinical applications, particularly in the field of oncohematology. Biosensors have recently been developed in order to improve the diagnosis and treatment of patients affected by hematological malignancies, such as the biosensor for assessing the in vitro pre-treatment efficacy of cytarabine in acute myeloid leukemia, and the fluorescence resonance energy transfer-based biosensor for assessing the efficacy of imatinib in chronic myeloid leukemia. The review also considers the challenges and future perspectives of biosensors in clinical practice.

  18. A luminescent nisin biosensor

    Immonen, Nina; Karp, Matti

    2006-02-01

    Nisin is a lantibiotic, an antibacterial peptide produced by certain Lactococcus lactis strains that kills or inhibits the growth of other bacteria. Nisin is widely used as a food preservative, and its long-time use suggests that it can be generally regarded as safe. We have developed a method for determining the amount of nisin in food samples that is based on luminescent biosensor bacteria. Bacterial luciferase operon luxABCDE was inserted into plasmid pNZ8048, and the construct was transformed by electroporation into Lc. lactis strain NZ9800, whose ability to produce nisin has been erased by deletion of the gene nisA. The operon luxABCDE has been modified to be functional in gram-positive bacteria to confer a bioluminescent phenotype without the requirement of adding an exogenous substrate. In the plasmid pNZ8048, the operon was placed under control of the nisin-inducible nisA promoter. The chromosomal nisRK genes of Lc. lactis NZ9800 allow it to sense nisin in the environment and relay this signal via signal transduction proteins NisK and NisR to initiate transcription from nisA promoter. In the case of our sensor bacteria, this leads to production of luciferase and, thus, luminescence that can be directly measured from living bacteria. Luminescence can be detected as early as within minutes of induction. The nisin assay described here provides a detection limit in the sub-picogram level per ml, and a linear area between 1 - 1000 pg/ml. The sensitivity of this assay exceeds the performance of all previously published methods.

  19. Overview of Human-Centric Space Situational Awareness (SSA) Science and Technology (S&T)

    Ianni, J.; Aleva, D.; Ellis, S.

    2012-09-01

    A number of organizations, within the government, industry, and academia, are researching ways to help humans understand and react to events in space. The problem is both helped and complicated by the fact that there are numerous data sources that need to be planned (i.e., tasked), collected, processed, analyzed, and disseminated. A large part of the research is in support of the Joint Space Operational Center (JSpOC), National Air and Space Intelligence Center (NASIC), and similar organizations. Much recent research has been specifically targeting the JSpOC Mission System (JMS) which has provided a unifying software architecture. This paper will first outline areas of science and technology (S&T) related to human-centric space situational awareness (SSA) and space command and control (C2) including: 1. Object visualization - especially data fused from disparate sources. Also satellite catalog visualizations that convey the physical relationships between space objects. 2. Data visualization - improve data trend analysis as in visual analytics and interactive visualization; e.g., satellite anomaly trends over time, space weather visualization, dynamic visualizations 3. Workflow support - human-computer interfaces that encapsulate multiple computer services (i.e., algorithms, programs, applications) into a 4. Command and control - e.g., tools that support course of action (COA) development and selection, tasking for satellites and sensors, etc. 5. Collaboration - improve individuals or teams ability to work with others; e.g., video teleconferencing, shared virtual spaces, file sharing, virtual white-boards, chat, and knowledge search. 6. Hardware/facilities - e.g., optimal layouts for operations centers, ergonomic workstations, immersive displays, interaction technologies, and mobile computing. Secondly we will provide a survey of organizations working these areas and suggest where more attention may be needed. Although no detailed master plan exists for human

  20. NASA Space Technology Draft Roadmap Area 13: Ground and Launch Systems Processing

    Clements, Greg

    2011-01-01

    This slide presentation reviews the technology development roadmap for the area of ground and launch systems processing. The scope of this technology area includes: (1) Assembly, integration, and processing of the launch vehicle, spacecraft, and payload hardware (2) Supply chain management (3) Transportation of hardware to the launch site (4) Transportation to and operations at the launch pad (5) Launch processing infrastructure and its ability to support future operations (6) Range, personnel, and facility safety capabilities (7) Launch and landing weather (8) Environmental impact mitigations for ground and launch operations (9) Launch control center operations and infrastructure (10) Mission integration and planning (11) Mission training for both ground and flight crew personnel (12) Mission control center operations and infrastructure (13) Telemetry and command processing and archiving (14) Recovery operations for flight crews, flight hardware, and returned samples. This technology roadmap also identifies ground, launch and mission technologies that will: (1) Dramatically transform future space operations, with significant improvement in life-cycle costs (2) Improve the quality of life on earth, while exploring in co-existence with the environment (3) Increase reliability and mission availability using low/zero maintenance materials and systems, comprehensive capabilities to ascertain and forecast system health/configuration, data integration, and the use of advanced/expert software systems (4) Enhance methods to assess safety and mission risk posture, which would allow for timely and better decision making. Several key technologies are identified, with a couple of slides devoted to one of these technologies (i.e., corrosion detection and prevention). Development of these technologies can enhance life on earth and have a major impact on how we can access space, eventually making routine commercial space access and improve building and manufacturing, and weather

  1. Space Solar Power Exploratory Research and Technology (SERT) Technical Interchange Meeting 2 (SERT TIM 2)

    Howell, Joe; Sanders, Clark W.

    2000-01-01

    The University of Alabama in Huntsville's (UAH) Propulsion Research Center hosted the Space Solar Power Exploratory Research & Technology (SERT) Technical Interchange Meeting TIM) 2 in Huntsville, Alabama December 7-10. 1999 with 126 people in attendance. The SERT program includes both competitively procured activities. which are being implemented through a portfolio of focused R&D investments--with the maximum leveraging of existing resources inside and outside NASA. and guided by these system studies. Axel Roth. Director of the Flight Projects Directorate NASA MSFC, welcomed the SERT TIM 2 participants and challenged them to develop the necessary technologies and demonstrations that will lead to Space Solar Power (SSP) International implementation. Joe Howell, NASA MSFC, reiterated the SERT TIM 2 objectives: 1) Refining and modeling systems approaches for the utilization of SSP concepts and technologies, ranging, from the near-term e.g. for space science, exploration and commercial space applications to the far-term (e. g. SSP for terrestrial markets), including systems concepts, technology, infrastructure (i.g., transportation), and economics. 2) Conducting technology research, development and demonstration activities to produce "proof- of-concept" validation of critical SSP elements for both the nearer and farther-term applications. 3) Initiating partnerships Nationality and Internationally that could be expanded, as appropriate, to pursue later SSP technology and applications (e.g., space science. colonization, etc.). Day one began with the NASA Centers presenting their SERT activities summary since SERT TIM 1 and wound up with a presentation by Masahiro Mori, NASDA titled "NASDA In-house Study for SSP". Demonstration for the Near-Term. Day two began with the SERT Systems Studies and Analysis reports resulting from NRA 8-23 followed by presentations of SERT Technology Demonstrations reports resulting from NRA 8-23. Day two closed with John Mankins presentation

  2. Hybrid structures based on gold nanoparticles and semiconductor quantum dots for biosensor applications

    Kurochkina M

    2018-04-01

    Full Text Available Margarita Kurochkina,1 Elena Konshina,1 Aleksandr Oseev,2 Soeren Hirsch3 1Centre of Information Optical Technologies, ITMO University, Saint Petersburg, Russia; 2Institute of Micro and Sensor Systems, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany; 3Department of Engineering, University of Applied Sciences Brandenburg, Brandenburg an der Havel, Germany Background: The luminescence amplification of semiconductor quantum dots (QD in the presence of self-assembled gold nanoparticles (Au NPs is one of way for creating biosensors with highly efficient transduction. Aims: The objective of this study was to fabricate the hybrid structures based on semiconductor CdSe/ZnS QDs and Au NP arrays and to use them as biosensors of protein. Methods: In this paper, the hybrid structures based on CdSe/ZnS QDs and Au NP arrays were fabricated using spin coating processes. Au NP arrays deposited on a glass wafer were investigated by optical microscopy and absorption spectroscopy depending on numbers of spin coating layers and their baking temperature. Bovine serum albumin (BSA was used as the target protein analyte in a phosphate buffer. A confocal laser scanning microscope was used to study the luminescent properties of Au NP/QD hybrid structures and to test BSA. Results: The dimensions of Au NP aggregates increased and the space between them decreased with increasing processing temperature. At the same time, a blue shift of the plasmon resonance peak in the absorption spectra of Au NP arrays was observed. The deposition of CdSe/ZnS QDs with a core diameter of 5 nm on the surface of the Au NP arrays caused an increase in absorption and a red shift of the plasmon peak in the spectra. The exciton–plasmon enhancement of the QDs’ photoluminescence intensity has been obtained at room temperature for hybrid structures with Au NPs array pretreated at temperatures of 100°C and 150°C. It has been found that an increase in the weight content of BSA

  3. Advanced Space Transportation Concepts and Propulsion Technologies for a New Delivery Paradigm

    Robinson, John W.; McCleskey, Carey M.; Rhodes, Russel E.; Lepsch, Roger A.; Henderson, Edward M.; Joyner, Claude R., III; Levack, Daniel J. H.

    2013-01-01

    This paper describes Advanced Space Transportation Concepts and Propulsion Technologies for a New Delivery Paradigm. It builds on the work of the previous paper "Approach to an Affordable and Productive Space Transportation System". The scope includes both flight and ground system elements, and focuses on their compatibility and capability to achieve a technical solution that is operationally productive and also affordable. A clear and revolutionary approach, including advanced propulsion systems (advanced LOX rich booster engine concept having independent LOX and fuel cooling systems, thrust augmentation with LOX rich boost and fuel rich operation at altitude), improved vehicle concepts (autogeneous pressurization, turbo alternator for electric power during ascent, hot gases to purge system and keep moisture out), and ground delivery systems, was examined. Previous papers by the authors and other members of the Space Propulsion Synergy Team (SPST) focused on space flight system engineering methods, along with operationally efficient propulsion system concepts and technologies. This paper continues the previous work by exploring the propulsion technology aspects in more depth and how they may enable the vehicle designs from the previous paper. Subsequent papers will explore the vehicle design, the ground support system, and the operations aspects of the new delivery paradigm in greater detail.

  4. HI-STAR. Health Improvements through Space Technologies and Resources: Executive Summary

    Finarelli, Margaret G.

    2002-01-01

    Our mission is to develop and promote a global strategy to help combat malaria using space technology. Like the tiny yet powerful mosquito, HI-STAR (Health Improvements Through Space Technologies and Resources) is a small program that aspires to make a difference. Timely detection of malaria danger zones is essential to help health authorities and policy makers make decisions about how to manage limited resources for combating malaria. In 2001, the technical support network for prevention and control of malaria epidemics published a study. HI-STAR focuses on malaria because it is the most common and deadly of the vector-borne diseases. Malaria also shares many commonalities with other diseases, which means the global strategy developed here may also be applicable to other parasitic diseases. HI-STAR would like to contribute to the many malaria groups already making great strides in the fight against malaria. Some examples include: Roll Back Malaria, The Special Program for Research and Training in Tropical Diseases (TDR) and the Multilateral Initiative on Malaria (MIM). Other important groups that are among the first to include space technologies in their model include: The Center for Health Application of Aerospace Related Technologies (CHAART) and Mapping Malaria Risk in Africa (MARA). Malaria is a complex and multi-faceted disease. Combating it must therefore be equally versatile. HI-STAR incorporates an interdisciplinary, international, intercultural approach.called 'Malaria Early Warning Systems; Concepts, Indicators and Partners.' This study, funded by Roll Back Malaria, a World Health Organization initiative, offers a framework for a monitoring and early warning system. HI-STAR seeks to build on this proposal and enhance the space elements of the suggested framework. It is the work of fifty-three professionals and students from the International Space University's 2002 Summer Session Program held in California, USA.

  5. INVESTIGATION OF MARKETING TECHNOLOGIES IN THE INNOVATION PROCESS OF ROCKET AND SPACE INDUSTRY

    K. B. Dobrova

    2016-01-01

    Full Text Available In this article we have studied the use of marketing technologies in the innovation process of enterprises of rocket and space industry. The present study specifies the relevance of chosen research topic, as well as the essence of marketing innovations at the enterprises of rocket and space industry, the structuring of marketing and management processes in the innovation process. There are provided the most common analytical instruments in the marketing and there is marked the importance of use of a global strategy for the enterprises of rocket and space industry. The article also specifies a clear example of application of marketing technologies in the innovation process of the Federal State Unitary Enterprise "State Space Research and Production Center named after Khrunichev M.V'.'. At the beginning the role and place of innovation management and innovation process in the strategic management of the FSUE "SSRPC named after Khrunichev M.V." are shown. Then there are described the basic marketing methods of program-oriented management of the innovation process in the FSUE "SSRPC named after Khrunichev M.V"" and there is highlighted the innovation marketing strategy of the FSUE "SSRPC named after Khrunichev M.V.". There are presented the distinctive features of the competitive strategy of the company of the rocket and space industry and the features of formation (development of the innovative enterprise development strategy based on marketing innovation in the FSUE "SSRPC named after Khrunichev M.V.". The conclusion includes the main findings of the study conducted.

  6. Lyndon B. Johnson Space Center (JSC) proposed dual-use technology investment program in intelligent robots

    Erikson, Jon D.

    1994-01-01

    This paper presents an overview of the proposed Lyndon B. Johnson Space Center (JSC) precompetitive, dual-use technology investment project in robotics. New robotic technology in advanced robots, which can recognize and respond to their environments and to spoken human supervision so as to perform a variety of combined mobility and manipulation tasks in various sectors, is an obejective of this work. In the U.S. economy, such robots offer the benefits of improved global competitiveness in a critical industrial sector; improved productivity by the end users of these robots; a growing robotics industry that produces jobs and profits; lower cost health care delivery with quality improvements; and, as these 'intelligent' robots become acceptable throughout society, an increase in the standard of living for everyone. In space, such robots will provide improved safety, reliability, and productivity as Space Station evolves, and will enable human space exploration (by human/robot teams). The proposed effort consists of partnerships between manufacturers, universities, and JSC to develop working production prototypes of these robots by leveraging current development by both sides. Currently targeted applications are in the manufacturing, health care, services, and construction sectors of the U.S. economy and in the inspection, servicing, maintenance, and repair aspects of space exploration. But the focus is on the generic software architecture and standardized interfaces for custom modules tailored for the various applications allowing end users to customize a robot as PC users customize PC's. Production prototypes would be completed in 5 years under this proposal.

  7. Technology, Educator Intention, and Relationships in Virtual Learning Spaces: A Qualitative Metasynthesis.

    Gdanetz, Lorraine M; Hamer, Mika K; Thomas, Eileen; Tarasenko, Lindsey M; Horton-Deutsch, Sara; Jones, Jacqueline

    2018-04-01

    A main concern that remains with the continued growth of online nursing education programs is the way educator and student relationships can be affected by new technologies. This interpretive study aims to gain an understanding of how technology influences the development of interpersonal relationships between the student and faculty in a virtual learning environment. Using an established structured approach to qualitative metasynthesis, a search was conducted using PubMed, EBSCO, CINAHL, Medline, ProQuest, Ovid Nursing databases, and Google Scholar, focused on caring and relational aspects of online nursing education. Technology alters communication, thereby positioning the intentionality of the educator at the heart of interpersonal relationship development in virtual learning spaces. This interpretive synthesis of prior qualitative research supports the development of a framework for online nursing courses, the need for continuing education of nursing faculty, the value of caring intentions, and enhancement of the educator's technological proficiency. [J Nurs Educ. 2018;57(4):197-202.]. Copyright 2018, SLACK Incorporated.

  8. Selling the Space Telescope - The interpenetration of science, technology, and politics

    Smith, Robert W.

    1991-01-01

    Attention is given to the politics of initiating the Space Telescope program and to the manner in which the coalition, or working consensus, for the Telescope was assembled, in particular, the role played by astronomers. It is contended that what ensued was a case study in the influence of government patronage on a large-scale scientific and technological program. It is concluded that while a politically feasible Space Telescope did result, in the selling process the Telescope had been both oversold and underfunded.

  9. Simulation of Cascaded Longitudinal-Space-Charge Amplifier at the Fermilab Accelerator Science & Technology (Fast) Facility

    Halavanau, A. [Northern Illinois U.; Piot, P. [Northern Illinois U.

    2015-12-01

    Cascaded Longitudinal Space Charge Amplifiers (LSCA) have been proposed as a mechanism to generate density modulation over a board spectral range. The scheme has been recently demonstrated in the optical regime and has confirmed the production of broadband optical radiation. In this paper we investigate, via numerical simulations, the performance of a cascaded LSCA beamline at the Fermilab Accelerator Science & Technology (FAST) facility to produce broadband ultraviolet radiation. Our studies are carried out using elegant with included tree-based grid-less space charge algorithm.

  10. Spacecraft Conceptual Design for the 8-Meter Advanced Technology Large Aperture Space Telescope (ATLAST)

    Hopkins, Randall C.; Capizzo, Peter; Fincher, Sharon; Hornsby, Linda S.; Jones, David

    2010-01-01

    The Advanced Concepts Office at Marshall Space Flight Center completed a brief spacecraft design study for the 8-meter monolithic Advanced Technology Large Aperture Space Telescope (ATLAST-8m). This spacecraft concept provides all power, communication, telemetry, avionics, guidance and control, and thermal control for the observatory, and inserts the observatory into a halo orbit about the second Sun-Earth Lagrange point. The multidisciplinary design team created a simple spacecraft design that enables component and science instrument servicing, employs articulating solar panels for help with momentum management, and provides precise pointing control while at the same time fast slewing for the observatory.

  11. A&R challenges for in-space operations. [Automation and Robotic technologies

    Underwood, James

    1990-01-01

    Automation and robotics (A&R) challenges for in-space operations are examined, with emphasis on the interaction between developing requirements, developing solutions, design concepts, and the nature of the applicability of automation in robotic technologies. Attention is first given to the use of A&R in establishing outposts on the moon and Mars. Then emphasis is placed on the requirements for the assembly of transportation systems in low earth orbit. Concepts of the Space Station which show how the assembly, processing, and checkout of systems in LEO might be accommodated are examined.

  12. Unpacking Virtual and Intercultural Spaces: A Presentation of a Conceptual Framework to Investigate the Connection between Technology and Intercultural Learning

    Pedersen, Rikke; Jørgensen, Mette; Harrison, Roger

    This paper presents a framework for the development of research within the emerging areas of internationalisation and technology that connect to build potential learning spaces within intercultural and global settings.......This paper presents a framework for the development of research within the emerging areas of internationalisation and technology that connect to build potential learning spaces within intercultural and global settings....

  13. Nanopatterned Bulk Metallic Glass Biosensors.

    Kinser, Emily R; Padmanabhan, Jagannath; Yu, Roy; Corona, Sydney L; Li, Jinyang; Vaddiraju, Sagar; Legassey, Allen; Loye, Ayomiposi; Balestrini, Jenna; Solly, Dawson A; Schroers, Jan; Taylor, André D; Papadimitrakopoulos, Fotios; Herzog, Raimund I; Kyriakides, Themis R

    2017-12-22

    Nanopatterning as a surface area enhancement method has the potential to increase signal and sensitivity of biosensors. Platinum-based bulk metallic glass (Pt-BMG) is a biocompatible material with electrical properties conducive for biosensor electrode applications, which can be processed in air at comparably low temperatures to produce nonrandom topography at the nanoscale. Work presented here employs nanopatterned Pt-BMG electrodes functionalized with glucose oxidase enzyme to explore the impact of nonrandom and highly reproducible nanoscale surface area enhancement on glucose biosensor performance. Electrochemical measurements including cyclic voltammetry (CV) and amperometric voltammetry (AV) were completed to compare the performance of 200 nm Pt-BMG electrodes vs Flat Pt-BMG control electrodes. Glucose dosing response was studied in a range of 2 mM to 10 mM. Effective current density dynamic range for the 200 nm Pt-BMG was 10-12 times greater than that of the Flat BMG control. Nanopatterned electrode sensitivity was measured to be 3.28 μA/cm 2 /mM, which was also an order of magnitude greater than the flat electrode. These results suggest that nonrandom nanotopography is a scalable and customizable engineering tool which can be integrated with Pt-BMGs to produce biocompatible biosensors with enhanced signal and sensitivity.

  14. Improved Ion-Channel Biosensors

    Nadeau, Jay; White, Victor; Dougherty, Dennis; Maurer, Joshua

    2004-01-01

    An effort is underway to develop improved biosensors of a type based on ion channels in biomimetic membranes. These sensors are microfabricated from silicon and other materials compatible with silicon. As described, these sensors offer a number of advantages over prior sensors of this type.

  15. An electromagnetic system for biosensors

    2008-01-01

    The invention relates to an electromagnetic system for biosensors, in which the system can switch quickly between high magnetic gradients, without the need of movement of mech. elements. This is realized by two independent emu which are sepd. in the region of the pole shoes over a gap, in which a

  16. Fiber optic-based biosensor

    Ligler, Frances S.

    1991-01-01

    The NRL fiber optic biosensor is a device which measures the formation of a fluorescent complex at the surface of an optical fiber. Antibodies and DNA binding proteins provide the mechanism for recognizing an analyze and immobilizing a fluorescent complex on the fiber surface. The fiber optic biosensor is fast, sensitive, and permits analysis of hazardous materials remote from the instrumentation. The fiber optic biosensor is described in terms of the device configuration, chemistry for protein immobilization, and assay development. A lab version is being used for assay development and performance characterization while a portable device is under development. Antibodies coated on the fiber are stable for up to two years of storage prior to use. The fiber optic biosensor was used to measure concentration of toxins in the parts per billion (ng/ml) range in under a minute. Immunoassays for small molecules and whole bacteria are under development. Assays using DNA probes as the detection element can also be used with the fiber optic sensor, which is currently being developed to detect biological warfare agents, explosives, pathogens, and toxic materials which pollute the environment.

  17. Biosensors and multiple mycotoxin analysis

    Gaag, B. van der; Spath, S.; Dietrich, H.; Stigter, E.; Boonzaaijer, G.; Osenbruggen, T. van; Koopal, K.

    2003-01-01

    An immunochemical biosensor assay for the detection of multiple mycotoxins in a sample is described.The inhibition assay is designed to measure four different mycotoxins in a single measurement, following extraction, sample clean-up and incubation with an appropriate cocktail of anti-mycotoxin

  18. Biosensor-based diagnostics of contaminated groundwater: assessment and remediation strategy

    Bhattacharyya, Jessica; Read, David; Amos, Sean; Dooley, Stephen; Killham, Kenneth; Paton, Graeme I.

    2005-01-01

    Shallow groundwater beneath a former airfield site in southern England has been heavily contaminated with a wide range of chlorinated solvents. The feasibility of using bacterial biosensors to complement chemical analysis and enable cost-effective, and focussed sampling has been assessed as part of a site evaluation programme. Five different biosensors, three metabolic (Vibrio fischeri, Pseudomonas fluorescens 10568 and Escherichia coli HB101) and two catabolic (Pseudomonas putida TVA8 and E. coli DH5α), were employed to identify areas where the availability and toxicity of pollutants is of most immediate environmental concern. The biosensors used showed different sensitivities to each other and to the groundwater samples tested. There was generally a good agreement with chemical analyses. The potential efficacy of remediation strategies was explored by coupling sample manipulation to biosensor tests. Manipulation involved sparging and charcoal treatment procedures to simulate remediative engineering solutions. Sparging was sufficient at most locations. - Luminescent bacteria complement chemical analysis and support remediation technology

  19. A High-Content Assay for Biosensor Validation and for Examining Stimuli that Affect Biosensor Activity.

    Slattery, Scott D; Hahn, Klaus M

    2014-12-01

    Biosensors are valuable tools used to monitor many different protein behaviors in vivo. Demand for new biosensors is high, but their development and characterization can be difficult. During biosensor design, it is necessary to evaluate the effects of different biosensor structures on specificity, brightness, and fluorescence responses. By co-expressing the biosensor with upstream proteins that either stimulate or inhibit the activity reported by the biosensor, one can determine the difference between the biosensor's maximally activated and inactivated state, and examine response to specific proteins. We describe here a method for biosensor validation in a 96-well plate format using an automated microscope. This protocol produces dose-response curves, enables efficient examination of many parameters, and unlike cell suspension assays, allows visual inspection (e.g., for cell health and biosensor or regulator localization). Optimization of single-chain and dual-chain Rho GTPase biosensors is addressed, but the assay is applicable to any biosensor that can be expressed or otherwise loaded in adherent cells. The assay can also be used for purposes other than biosensor validation, using a well-characterized biosensor as a readout for effects of upstream molecules. Copyright © 2014 John Wiley & Sons, Inc.

  20. Status and Mission Applicability of NASA's In-Space Propulsion Technology Project

    Anderson, David J.; Munk, Michelle M.; Dankanich, John; Pencil, Eric; Liou, Larry

    2009-01-01

    The In-Space Propulsion Technology (ISPT) project develops propulsion technologies that will enable or enhance NASA robotic science missions. Since 2001, the ISPT project developed and delivered products to assist technology infusion and quantify mission applicability and benefits through mission analysis and tools. These in-space propulsion technologies are applicable, and potentially enabling for flagship destinations currently under evaluation, as well as having broad applicability to future Discovery and New Frontiers mission solicitations. This paper provides status of the technology development, near-term mission benefits, applicability, and availability of in-space propulsion technologies in the areas of advanced chemical thrusters, electric propulsion, aerocapture, and systems analysis tools. The current chemical propulsion investment is on the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance for lower cost. Investments in electric propulsion technologies focused on completing NASA's Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system, and the High Voltage Hall Accelerator (HiVHAC) thruster, which is a mid-term product specifically designed for a low-cost electric propulsion option. Aerocapture investments developed a family of thermal protections system materials and structures; guidance, navigation, and control models of blunt-body rigid aeroshells; atmospheric models for Earth, Titan, Mars and Venus; and models for aerothermal effects. In 2009 ISPT started the development of propulsion technologies that would enable future sample return missions. The paper describes the ISPT project's future focus on propulsion for sample return missions. The future technology development areas for ISPT is: Planetary Ascent Vehicles (PAV), with a Mars Ascent Vehicle (MAV) being the initial development focus; multi-mission technologies for Earth Entry Vehicles (MMEEV) needed