WorldWideScience

Sample records for sp model expectations

  1. Expectancy Theory Modeling

    Science.gov (United States)

    1982-08-01

    accomplish the task, (2) the instrumentality of task performance for job outcomes, and (3) the instrumentality of outcomes for need satisfaction . We...in this discussion: effort, performance , outcomes, and needs. In order to present briefly the conventional approach to the Vroom models, another...Presumably, this is the final event in the sequence of effort, performance , outcome, and need satisfaction . The actual research reported in expectancy

  2. The Probability Model of Expectation Disconfirmation Process

    Directory of Open Access Journals (Sweden)

    Hui-Hsin HUANG

    2015-06-01

    Full Text Available This paper proposes a probability model to explore the dynamic process of customer’s satisfaction. Bases on expectation disconfirmation theory, the satisfaction is constructed with customer’s expectation before buying behavior and the perceived performance after purchase. The experiment method is designed to measure expectation disconfirmation effects and we also use the collection data to estimate the overall satisfaction and model calibration. The results show good fitness between the model and the real data. This model has application for business marketing areas in order to manage relationship satisfaction.

  3. Expected commodity returns and pricing models

    International Nuclear Information System (INIS)

    Cortazar, Gonzalo; Kovacevic, Ivo; Schwartz, Eduardo S.

    2015-01-01

    Stochastic models of commodity prices have evolved considerably in terms of their structure and the number and interpretation of the state variables that model the underlying risk. Using multiple factors, different specifications and modern estimation techniques, these models have gained wide acceptance because of their success in accurately fitting the observed commodity futures' term structures and their dynamics. It is not well emphasized however that these models, in addition to providing the risk neutral distribution of future spot prices, also provide their true distribution. While the parameters of the risk neutral distribution are estimated more precisely and are usually statistically significant, some of the parameters of the true distribution are typically measured with large errors and are statistically insignificant. In this paper we argue that to increase the reliability of commodity pricing models, and therefore their use by practitioners, some of their parameters — in particular the risk premium parameters — should be obtained from other sources and we show that this can be done without losing any precision in the pricing of futures contracts. We show how the risk premium parameters can be obtained from estimations of expected futures returns and provide alternative procedures for estimating these expected futures returns. - Highlights: • Simple methodology to improve the performance of commodity pricing models • New information about commodity futures expected return is added to the estimation. • No significant effect in pricing futures contracts is observed. • More reliable commodity pricing model's expected returns are obtained. • Methodology is open to any expected futures return model preferred by practitioner

  4. A multiresolution model of rhythmic expectancy

    NARCIS (Netherlands)

    Smith, L.M.; Honing, H.; Miyazaki, K.; Hiraga, Y.; Adachi, M.; Nakajima, Y.; Tsuzaki, M.

    2008-01-01

    We describe a computational model of rhythmic cognition that predicts expected onset times. A dynamic representation of musical rhythm, the multiresolution analysis using the continuous wavelet transform is used. This representation decomposes the temporal structure of a musical rhythm into time

  5. Heterogeneous expectations in monetary DSGE models

    NARCIS (Netherlands)

    Massaro, D.

    2013-01-01

    This paper derives a general New Keynesian framework with heterogeneous expectations by explicitly solving the micro-foundations underpinning the model. The resulting reduced form is analytically tractable and encompasses the representative rational agent benchmark as a special case. We specify a

  6. SpF: Enabling Petascale Performance for Pseudospectral Dynamo Models

    Science.gov (United States)

    Jiang, W.; Clune, T.; Vriesema, J.; Gutmann, G.

    2013-12-01

    Pseudospectral (PS) methods possess a number of characteristics (e.g., efficiency, accuracy, natural boundary conditions) that are extremely desirable for dynamo models. Unfortunately, dynamo models based upon PS methods face a number of daunting challenges, which include exposing additional parallelism, leveraging hardware accelerators, exploiting hybrid parallelism, and improving the scalability of global memory transposes. Although these issues are a concern for most models, solutions for PS methods tend to require far more pervasive changes to underlying data and control structures. Further, improvements in performance in one model are difficult to transfer to other models, resulting in significant duplication of effort across the research community. We have developed an extensible software framework for pseudospectral methods called SpF that is intended to enable extreme scalability and optimal performance. High-level abstractions provided by SpF unburden applications of the responsibility of managing domain decomposition and load balance while reducing the changes in code required to adapt to new computing architectures. The key design concept in SpF is that each phase of the numerical calculation is partitioned into disjoint numerical 'kernels' that can be performed entirely in-processor. The granularity of domain-decomposition provided by SpF is only constrained by the data-locality requirements of these kernels. SpF builds on top of optimized vendor libraries for common numerical operations such as transforms, matrix solvers, etc., but can also be configured to use open source alternatives for portability. SpF includes several alternative schemes for global data redistribution and is expected to serve as an ideal testbed for further research into optimal approaches for different network architectures. In this presentation, we will describe the basic architecture of SpF as well as preliminary performance data and experience with adapting legacy dynamo codes

  7. Expectations

    DEFF Research Database (Denmark)

    depend on the reader’s own experiences, individual feelings, personal associations or on conventions of reading, interpretive communities and cultural conditions? This volume brings together narrative theory, fictionality theory and speech act theory to address such questions of expectations...

  8. Rank dependent expected utility models of tax evasion.

    OpenAIRE

    Erling Eide

    2001-01-01

    In this paper the rank-dependent expected utility theory is substituted for the expected utility theory in models of tax evasion. It is demonstrated that the comparative statics results of the expected utility, portfolio choice model of tax evasion carry over to the more general rank dependent expected utility model.

  9. GRRR. The EXPECT groundwater model for transport of solutes

    NARCIS (Netherlands)

    Meijers R; Sauter FJ; Veling EJM; van Grinsven JJM; Leijnse A; Uffink GJM; MTV; CWM; LBG

    1994-01-01

    In this report the design and first test results are presented of the EXPECT groundwater module for transport of solutes GRRR (GRoundwater source Receptor Relationships). This model is one of the abiotic compartment modules of the EXPECT model. The EXPECT model is a tool for scenario development

  10. Rational expectations modelling in O.R

    OpenAIRE

    Phelps, R I; Warwick, J P

    1984-01-01

    The conventional OR approach to managing a system is, in outline, firstly to create a model of the existing system, secondly, to investigate changes in the model which improve or control the behaviour of the model and thirdly, to implement these changes in the system. It is assumed that the model incorporating these changes will be a valid representation of the system after the changes, in as far as the original model was a valid representation of the original system, and can thus be used to ...

  11. Integration of multiple, excess, backup, and expected covering models

    OpenAIRE

    M S Daskin; K Hogan; C ReVelle

    1988-01-01

    The concepts of multiple, excess, backup, and expected coverage are defined. Model formulations using these constructs are reviewed and contrasted to illustrate the relationships between them. Several new formulations are presented as is a new derivation of the expected covering model which indicates more clearly the relationship of the model to other multi-state covering models. An expected covering model with multiple time standards is also presented.

  12. Solving rational expectations models using Excel

    DEFF Research Database (Denmark)

    Strulik, Holger

    2004-01-01

    Problems of discrete time optimal control can be solved using backward iteration and Microsoft Excel. The author explains the method in general and shows how the basic models of neoclassical growth and real business cycles are solved......Problems of discrete time optimal control can be solved using backward iteration and Microsoft Excel. The author explains the method in general and shows how the basic models of neoclassical growth and real business cycles are solved...

  13. Using survey data on inflation expectations in the estimation of learning and rational expectations models

    NARCIS (Netherlands)

    Ormeño, A.

    2012-01-01

    Do survey data on inflation expectations contain useful information for estimating macroeconomic models? I address this question by using survey data in the New Keynesian model by Smets and Wouters (2007) to estimate and compare its performance when solved under the assumptions of Rational

  14. Expectations and stability in oligopoly models

    CERN Document Server

    Okuguchi, Koji

    1976-01-01

    Ever since A.C.Cournot(1838), economists have been increasingly interested in oligopoly, a state of industry where firms producing homogeneous goods or close substitutes are limited in number. The fewness of firms in oligopoly gives rise to interdependence which they have to take into account in choosing their optimal output or pricing policies in each production period. Since each firm's profit is a function of all firms' outputs in an oligopoly without product differ­ entiation, each firm in choosing its optimal output in any period has to know beforehand all other rival firms' outputs in the same period. As this is in general impossible, it has to form some kind of expecta­ tion on other firms' most likely outputs. Cournot thought that in each period each firm assumed that all its rivals' outputs would remain at the same level as in the preceding period. Needless to say, the Cournot assumption is too naive to be realistically supported. However, the Cournot profit maximizing oligopoly model characterized...

  15. SP@CE - An SP-based programming model for consumer electronics streaming applications

    NARCIS (Netherlands)

    Varbanescu, Ana Lucia; Nijhuis, Maik; Escribano, Arturo González; Sips, Henk; Bos, Herbert; Bal, Henri

    2007-01-01

    Efficient programming of multimedia streaming applications for Consumer Electronics (CE) devices is not trivial. As a solution for this problem, we present SP@CE, a novel programming model designed to balance the specific requirements of CE streaming applications with the simplicity and efficiency

  16. The rational expectations equilibrium inventory model theory and applications

    CERN Document Server

    1989-01-01

    This volume consists of six essays that develop and/or apply "rational expectations equilibrium inventory models" to study the time series behavior of production, sales, prices, and inventories at the industry level. By "rational expectations equilibrium inventory model" I mean the extension of the inventory model of Holt, Modigliani, Muth, and Simon (1960) to account for: (i) discounting, (ii) infinite horizon planning, (iii) observed and unobserved by the "econometrician" stochastic shocks in the production, factor adjustment, storage, and backorders management processes of firms, as well as in the demand they face for their products; and (iv) rational expectations. As is well known according to the Holt et al. model firms hold inventories in order to: (a) smooth production, (b) smooth production changes, and (c) avoid stockouts. Following the work of Zabel (1972), Maccini (1976), Reagan (1982), and Reagan and Weitzman (1982), Blinder (1982) laid the foundations of the rational expectations equilibrium inve...

  17. Testing exact rational expectations in cointegrated vector autoregressive models

    DEFF Research Database (Denmark)

    Johansen, Søren; Swensen, Anders Rygh

    1999-01-01

    This paper considers the testing of restrictions implied by rational expectations hypotheses in a cointegrated vector autoregressive model for I(1) variables. If the rational expectations involve one-step-ahead observations only and the coefficients are known, an explicit parameterization...... of the restrictions is found, and the maximum-likelihood estimator is derived by regression and reduced rank regression. An application is given to a present value model....

  18. The Thomas-Fermi model: momentum expectation values

    International Nuclear Information System (INIS)

    Dmitrieva, I.K.; Plindov, G.I.

    1983-01-01

    Within the Thomas-Fermi model including the exchange interaction and contributions of strongly bound electrons, analytical expressions are obtained for all momentum expectation values and for some of the expectation values of powers of the electron density for an atom with an arbitrary degree of ionization. It is shown that a correct treatment of strongly bound electrons gives a quantitative estimate of and within 3 - 1 expansion coefficients for and are given as an explicit function of the electron number

  19. Subjective Expected Utility: A Model of Decision-Making.

    Science.gov (United States)

    Fischoff, Baruch; And Others

    1981-01-01

    Outlines a model of decision making known to researchers in the field of behavioral decision theory (BDT) as subjective expected utility (SEU). The descriptive and predictive validity of the SEU model, probability and values assessment using SEU, and decision contexts are examined, and a 54-item reference list is provided. (JL)

  20. Vacuum expectation values for four-fermion operators. Model estimates

    International Nuclear Information System (INIS)

    Zhitnitskij, A.R.

    1985-01-01

    Some simple models (a system with a heavy quark, the rarefied insatanton gas) are used to investigate the problem of factorizability. Characteristics of vacuum fluctuations responsible for saturation of four-fermion vacuum expectation values which are known phenomenologically are discussed. A qualitative agreement between the model and phenomenologic;l estimates has been noted

  1. Vacuum expectation values of four-fermion operators. Model estimates

    International Nuclear Information System (INIS)

    Zhitnitskii, A.R.

    1985-01-01

    Simple models (a system with a heavy quark, a rarefied instanton gas) are used to study problems of factorizability. A discussion is given of the characteristics of the vacuum fluctuations responsible for saturation of the phenomenologically known four-fermion vacuum expectation values. Qualitative agreement between the model and phenomenological estimates is observed

  2. The expected-outcome model of two-player games

    CERN Document Server

    Abramson, Bruce

    1990-01-01

    The Expected-Outcome Model of Two-Player Games deals with the expected-outcome model of two-player games, in which the relative merit of game-tree nodes, rather than board positions, is considered. The ambiguity of static evaluation and the problems it generates in the search system are examined and the development of a domain-independent static evaluator is described. Comprised of eight chapters, this book begins with an overview of the rationale for the mathematical study of games, followed by a discussion on some previous artificial intelligence (AI) research efforts on game-trees. The nex

  3. On a Graphical Technique for Evaluating Some Rational Expectations Models

    DEFF Research Database (Denmark)

    Johansen, Søren; Swensen, Anders R.

    2011-01-01

    Campbell and Shiller (1987) proposed a graphical technique for the present value model, which consists of plotting estimates of the spread and theoretical spread as calculated from the cointegrated vector autoregressive model without imposing the restrictions implied by the present value model....... In addition to getting a visual impression of the fit of the model, the purpose is to see if the two spreads are nevertheless similar as measured by correlation, variance ratio, and noise ratio. We extend these techniques to a number of rational expectation models and give a general definition of spread...

  4. Giving the Expectancy-Value Model a Heart

    OpenAIRE

    Henning, V.; Hennig-Thurau, T.; Feiereisen, S.

    2012-01-01

    Over the past decade, research in consumer behavior has debated the role of emotion in consumer decision making intensively but has offered few attempts to integrate emotion-related findings with established theoretical frameworks. This manuscript augments the classical expectancy-value model of attitude with a dimensional model of emotion. An experiment involving 308 college students who face actual purchase decisions shows that predictions of attitudes, behavioral intentions and actual beha...

  5. Business Processes Modeling Recommender Systems: User Expectations and Empirical Evidence

    Directory of Open Access Journals (Sweden)

    Michael Fellmann

    2018-04-01

    Full Text Available Recommender systems are in widespread use in many areas, especially electronic commerce solutions. In this contribution, we apply recommender functionalities to business process modeling and investigate their potential for supporting process modeling. To do so, we have implemented two prototypes, demonstrated them at a major fair and collected user feedback. After analysis of the feedback, we have confronted the findings with the results of the experiment. Our results indicate that fairgoers expect increased modeling speed as the key advantage and completeness of models as the most unlikely advantage. This stands in contrast to an initial experiment revealing that modelers, in fact, increase the completeness of their models when adequate knowledge is presented while time consumption is not necessarily reduced. We explain possible causes of this mismatch and finally hypothesize on two “sweet spots” of process modeling recommender systems.

  6. Fiscal Effectiveness and Debt Illusion in a Rational Expectations Model

    OpenAIRE

    Basil A. DALAMAGAS

    1993-01-01

    The question of how substitution of debt for taxes affects private sector wealth and consumption has long been an unresolved macroeconomic theory and policy dispute. The present study attempts to address this problem within a modified fiscal-illusion setting, by utilizing an explicit rational expectations optimizing model of consumer behaviour for a sample of six developed countries. The empirical evidence presented is strongly supportive of the assertion that consumers make their consumption...

  7. A 3-factor model for the FACIT-Sp.

    Science.gov (United States)

    Canada, Andrea L; Murphy, Patricia E; Fitchett, George; Peterman, Amy H; Schover, Leslie R

    2008-09-01

    The 12-item Functional Assessment of Chronic Illness Therapy-Spiritual Well-being Scale (FACIT-Sp) is a popular measure of the religious/spiritual (R/S) components of quality of life (QoL) in patients with cancer. The original factor analyses of the FACIT-Sp supported two factors: Meaning/Peace and Faith. Because Meaning suggests a cognitive aspect of R/S and Peace an affective component, we hypothesized a 3-factor solution: Meaning, Peace, and Faith. Participants were 240 long-term female survivors of cancer who completed the FACIT-Sp, the SF-12, and the BSI 18. We used confirmatory factor analysis to compare the 2- and 3-factor models of the FACIT-Sp and subsequently assessed associations between the resulting solutions and QoL domains. Survivors averaged 44 years of age and 10 years post-diagnosis. A 3-factor solution of the FACIT-Sp significantly improved the fit of the model to the data over the original 2-factor structure (Delta chi(2)=72.36, df=2, p<0.001). Further adjustments to the 3-factor model resulted in a final solution with even better goodness-of-fit indices (chi(2)=59.11, df=1, p=0.13, CFI=1.00, SMRM=0.05).The original Meaning/Peace factor controlling for Faith was associated with mental (r=0.63, p<0.000) and physical (r=0.22, p<0.01) health on the SF-12, and the original Faith factor controlling for Meaning/Peace was negatively associated with mental health (r=-0.15, p<0.05). The 3-factor model was more informative. Specifically, using partial correlations, the Peace factor was only related to mental health (r=0.53, p<0.001); Meaning was related to both physical (r=0.18, p<0.01) and mental (r=0.17, p<0.01) health; and Faith was negatively associated with mental health (r=-0.17, p<0.05). The results of this study support a 3-factor solution of the FACIT-Sp. The new solution not only represents a psychometric improvement over the original, but also enables a more detailed examination of the contribution of different dimensions of R/S to QoL. (c

  8. An Expectation-Maximization Method for Calibrating Synchronous Machine Models

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Da; Zhou, Ning; Lu, Shuai; Lin, Guang

    2013-07-21

    The accuracy of a power system dynamic model is essential to its secure and efficient operation. Lower confidence in model accuracy usually leads to conservative operation and lowers asset usage. To improve model accuracy, this paper proposes an expectation-maximization (EM) method to calibrate the synchronous machine model using phasor measurement unit (PMU) data. First, an extended Kalman filter (EKF) is applied to estimate the dynamic states using measurement data. Then, the parameters are calculated based on the estimated states using maximum likelihood estimation (MLE) method. The EM method iterates over the preceding two steps to improve estimation accuracy. The proposed EM method’s performance is evaluated using a single-machine infinite bus system and compared with a method where both state and parameters are estimated using an EKF method. Sensitivity studies of the parameter calibration using EM method are also presented to show the robustness of the proposed method for different levels of measurement noise and initial parameter uncertainty.

  9. Applying the Expectancy-Value Model to understand health values.

    Science.gov (United States)

    Zhang, Xu-Hao; Xie, Feng; Wee, Hwee-Lin; Thumboo, Julian; Li, Shu-Chuen

    2008-03-01

    Expectancy-Value Model (EVM) is the most structured model in psychology to predict attitudes by measuring attitudinal attributes (AAs) and relevant external variables. Because health value could be categorized as attitude, we aimed to apply EVM to explore its usefulness in explaining variances in health values and investigate underlying factors. Focus group discussion was carried out to identify the most common and significant AAs toward 5 different health states (coded as 11111, 11121, 21221, 32323, and 33333 in EuroQol Five-Dimension (EQ-5D) descriptive system). AAs were measured in a sum of multiplications of subjective probability (expectancy) and perceived value of attributes with 7-point Likert scales. Health values were measured using visual analog scales (VAS, range 0-1). External variables (age, sex, ethnicity, education, housing, marital status, and concurrent chronic diseases) were also incorporated into survey questionnaire distributed by convenience sampling among eligible respondents. Univariate analyses were used to identify external variables causing significant differences in VAS. Multiple linear regression model (MLR) and hierarchical regression model were used to investigate the explanatory power of AAs and possible significant external variable(s) separately or in combination, for each individual health state and a mixed scenario of five states, respectively. Four AAs were identified, namely, "worsening your quality of life in terms of health" (WQoL), "adding a burden to your family" (BTF), "making you less independent" (MLI) and "unable to work or study" (UWS). Data were analyzed based on 232 respondents (mean [SD] age: 27.7 [15.07] years, 49.1% female). Health values varied significantly across 5 health states, ranging from 0.12 (33333) to 0.97 (11111). With no significant external variables identified, EVM explained up to 62% of the variances in health values across 5 health states. The explanatory power of 4 AAs were found to be between 13

  10. A Verhulst model for microalgae Botryococcus sp. growth and nutrient removal in wastewater

    Science.gov (United States)

    Jamaian, Siti Suhana; Bakeri, Noorhadila Mohd; Sunar, Norshuhaila Mohamed; Gani, Paran

    2017-08-01

    Microalgae Botryococcus sp. is a colonial green alga found in lakes and reservoirs in Malaysia. Previous studies reported that the potential of Botryococcus sp. photosynthesis as a source of fuel. The Botryococcus sp. contains hydrocarbon up to 75% of dry weight, which can be converted into petrol, diesel or turbine fuel or other liquid or gaseous hydrocarbons. Recently, an experimental study was conducted on phycoremediation technology for wastewater using Botryococcus sp. The phycoremediation technology is useful to remove the excess of nutrients such as nitrogen, phosphorus and also have the ability to remove various pollutants from wastewater. This research implements the Verhulst model to estimate the nutrient removal by microalgae Botryococcus sp. from the wastewater. This model has been validated with the experiments of microalgae Botryococcus sp. grown in domestic and palm oil wastewater. The results suggested that microalgae Botryococcus sp. could be cultured in domestic and palm oil wastewater while nutrients are reduced from these wastewaters.

  11. ZNJPrice/Earnings Ratio Model through Dividend Yield and Required Yield Above Expected Inflation

    Directory of Open Access Journals (Sweden)

    Emil Mihalina

    2010-07-01

    Full Text Available Price/earnings ratio is the most popular and most widespread evaluation model used to assess relative capital asset value on financial markets. In functional terms, company earnings in the very long term can be described with high significance. Empirically, it is visible from long-term statistics that the demanded (required yield on capital markets has certain regularity. Thus, investors first require a yield above the stable inflation rate and then a dividend yield and a capital increase caused by the growth of earnings that influence the price, with the assumption that the P/E ratio is stable. By combining the Gordon model for current dividend value, the model of market capitalization of earnings (price/earnings ratio and bearing in mind the influence of the general price levels on company earnings, it is possible to adjust the price/earnings ratio by deriving a function of the required yield on capital markets measured by a market index through dividend yield and inflation rate above the stable inflation rate increased by profit growth. The S&P 500 index for example, has in the last 100 years grown by exactly the inflation rate above the stable inflation rate increased by profit growth. The comparison of two series of price/earnings ratios, a modelled one and an average 7-year ratio, shows a notable correlation in the movement of two series of variables, with a three year deviation. Therefore, it could be hypothesized that three years of the expected inflation level, dividend yield and profit growth rate of the market index are discounted in the current market prices. The conclusion is that, at the present time, the relationship between the adjusted average price/earnings ratio and its effect on the market index on one hand and the modelled price/earnings ratio on the other can clearly show the expected dynamics and course in the following period.

  12. Failure Analysis of Nonvolatile Residue (NVR) Analyzer Model SP-1000

    Science.gov (United States)

    Potter, Joseph C.

    2011-01-01

    National Aeronautics and Space Administration (NASA) subcontractor Wiltech contacted the NASA Electrical Lab (NE-L) and requested a failure analysis of a Solvent Purity Meter; model SP-IOOO produced by the VerTis Instrument Company. The meter, used to measure the contaminate in a solvent to determine the relative contamination on spacecraft flight hardware and ground servicing equipment, had been inoperable and in storage for an unknown amount of time. NE-L was asked to troubleshoot the unit and make a determination on what may be required to make the unit operational. Through the use of general troubleshooting processes and the review of a unit in service at the time of analysis, the unit was found to be repairable but would need the replacement of multiple components.

  13. Greater expectations: using hierarchical linear modeling to examine expectancy for treatment outcome as a predictor of treatment response.

    Science.gov (United States)

    Price, Matthew; Anderson, Page; Henrich, Christopher C; Rothbaum, Barbara Olasov

    2008-12-01

    A client's expectation that therapy will be beneficial has long been considered an important factor contributing to therapeutic outcomes, but recent empirical work examining this hypothesis has primarily yielded null findings. The present study examined the contribution of expectancies for treatment outcome to actual treatment outcome from the start of therapy through 12-month follow-up in a clinical sample of individuals (n=72) treated for fear of flying with either in vivo exposure or virtual reality exposure therapy. Using a piecewise hierarchical linear model, outcome expectancy predicted treatment gains made during therapy but not during follow-up. Compared to lower levels, higher expectations for treatment outcome yielded stronger rates of symptom reduction from the beginning to the end of treatment on 2 standardized self-report questionnaires on fear of flying. The analytic approach of the current study is one potential reason that findings contrast with prior literature. The advantages of using hierarchical linear modeling to assess interindividual differences in longitudinal data are discussed.

  14. 76 FR 73483 - Airworthiness Directives; Gulfstream Aerospace Corporation Model GV and GV-SP Airplanes

    Science.gov (United States)

    2011-11-29

    ... Management Branch, ACE-102A, FAA, Atlanta Aircraft Certification Office (ACO), 1701 Columbia Avenue, College... Airworthiness Directives; Gulfstream Aerospace Corporation Model GV and GV-SP Airplanes AGENCY: Federal Aviation... certain Gulfstream Aerospace Corporation Model GV and GV-SP airplanes. This AD was prompted by...

  15. Analysis of Salmonella sp bacterial contamination on Vannamei Shrimp using binary logit model approach

    Science.gov (United States)

    Oktaviana, P. P.; Fithriasari, K.

    2018-04-01

    Mostly Indonesian citizen consume vannamei shrimp as their food. Vannamei shrimp also is one of Indonesian exports comodities mainstay. Vannamei shrimp in the ponds and markets could be contaminated by Salmonella sp bacteria. This bacteria will endanger human health. Salmonella sp bacterial contamination on vannamei shrimp could be affected by many factors. This study is intended to identify what factors that supposedly influence the Salmonella sp bacterial contamination on vannamei shrimp. The researchers used the testing result of Salmonella sp bacterial contamination on vannamei shrimp as response variable. This response variable has two categories: 0 = if testing result indicate that there is no Salmonella sp on vannamei shrimp; 1 = if testing result indicate that there is Salmonella sp on vannamei shrimp. There are four factors that supposedly influence the Salmonella sp bacterial contamination on vannamei shrimp, which are the testing result of Salmonella sp bacterial contamination on farmer hand swab; the subdistrict of vannamei shrimp ponds; the fish processing unit supplied by; and the pond are in hectare. This four factors used as predictor variables. The analysis used is Binary Logit Model Approach according to the response variable that has two categories. The analysis result indicates that the factors or predictor variables which is significantly affect the Salmonella sp bacterial contamination on vannamei shrimp are the testing result of Salmonella sp bacterial contamination on farmer hand swab and the subdistrict of vannamei shrimp ponds.

  16. A Comprehensive Expectancy Motivation Model: Implications for Adult Education and Training.

    Science.gov (United States)

    Howard, Kenneth W.

    1989-01-01

    The Comprehensive Expectancy Motivation Model is based on valence-instrumentality-expectancy theory. It describes expectancy motivation as part of a larger process that includes past experience, motivation, effort, performance, reward, and need satisfaction. The model has significant implications for the design, marketing, and delivery of adult…

  17. The expected model of a cadastre in Poland

    Directory of Open Access Journals (Sweden)

    Jolanta Ciak

    2015-03-01

    Full Text Available A cadastre is a based on a cadastral map official register of land, property and other utilities that constitute subjects of taxation as well as the source of information on cadastral objects. As indicated in the reference books, it constitutes an institution of law, which in the social perception is seen as providing legal order in the scope of establishing the range of laws, of the sense of security resulting from the fact of the entering of the subjects of taxation and the possibility to exert one’s rights under the registration proceedings. However, the current shape of the register does not meet social expectations. The suggested reform of the taxation of property in Poland (cadastre meets numerous obstacles such as a formal and legal, political, financial or social barrier.

  18. The Optimal Portfolio Selection Model under g-Expectation

    Directory of Open Access Journals (Sweden)

    Li Li

    2014-01-01

    complicated and sophisticated, the optimal solution turns out to be surprisingly simple, the payoff of a portfolio of two binary claims. Also I give the economic meaning of my model and the comparison with that one in the work of Jin and Zhou, 2008.

  19. Receiver Expectations: Toward a New Model of Resistance to Persuasion.

    Science.gov (United States)

    Miller, Michael D.; Burgoon, Michael

    Communication research long has noted how pretreatment strategies ("inoculations") induce resistance to persuasion, but a new model proposes that resistance is an integral part of the persuasion process. Using the inoculation framework, researchers showed the importance of threats to an individual's attitudes in developing resistance to…

  20. Statistical model for expected un supplied energy; Statistisk modell for forventet ILE

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    Results from a statistical analysis of expected un supplied energy for Norwegian network companies are presented. The data are from the years 1996-2004. The estimation model includes several explanatory variables that together reflect the characteristics of the network, climatic aspects and other geographical conditions. The model has a high degree of accuracy when compared to the historical number of un supplied energy for about 90 percent of the network companies. But for 12 companies there are substantial, negative deviances that are not compatible with the available data. There is reason to believe that improved data for some types of variables can improve the accuracy of the model. In addition to establishing a norm for expected un supplied energy in the revenue estimations, the model can be used to reflect geographical constraints in NVEs (Norwegian Water and Energy directorate) efficiency analyses (ml)

  1. Probing for the Multiplicative Term in Modern Expectancy-Value Theory: A Latent Interaction Modeling Study

    Science.gov (United States)

    Trautwein, Ulrich; Marsh, Herbert W.; Nagengast, Benjamin; Ludtke, Oliver; Nagy, Gabriel; Jonkmann, Kathrin

    2012-01-01

    In modern expectancy-value theory (EVT) in educational psychology, expectancy and value beliefs additively predict performance, persistence, and task choice. In contrast to earlier formulations of EVT, the multiplicative term Expectancy x Value in regression-type models typically plays no major role in educational psychology. The present study…

  2. Higgs compositeness in Sp(2N) gauge theories — The pure gauge model

    Science.gov (United States)

    Bennett, Ed; Ki Hong, Deog; Lee, Jong-Wan; David Lin, C.-J.; Lucini, Biagio; Piai, Maurizio; Vadacchino, Davide

    2018-03-01

    As a first step in the study of Sp(2N) composite Higgs models, we obtained a set of novel numerical results for the pure gauge Sp(4) lattice theory in 3+1 space-time dimensions. Results for the continuum extrapolations of the string tension and the glueball mass spectrum are presented and their values are compared with the same quantities in neighbouring SU(N) models.

  3. Model Complexity and Out-of-Sample Performance: Evidence from S&P 500 Index Returns

    NARCIS (Netherlands)

    Kaeck, Andreas; Rodrigues, Paulo; Seeger, Norman J.

    We apply a range of out-of-sample specification tests to more than forty competing stochastic volatility models to address how model complexity affects out-of-sample performance. Using daily S&P 500 index returns, model confidence set estimations provide strong evidence that the most important model

  4. Computational-Model-Based Analysis of Context Effects on Harmonic Expectancy.

    Science.gov (United States)

    Morimoto, Satoshi; Remijn, Gerard B; Nakajima, Yoshitaka

    2016-01-01

    Expectancy for an upcoming musical chord, harmonic expectancy, is supposedly based on automatic activation of tonal knowledge. Since previous studies implicitly relied on interpretations based on Western music theory, the underlying computational processes involved in harmonic expectancy and how it relates to tonality need further clarification. In particular, short chord sequences which cannot lead to unique keys are difficult to interpret in music theory. In this study, we examined effects of preceding chords on harmonic expectancy from a computational perspective, using stochastic modeling. We conducted a behavioral experiment, in which participants listened to short chord sequences and evaluated the subjective relatedness of the last chord to the preceding ones. Based on these judgments, we built stochastic models of the computational process underlying harmonic expectancy. Following this, we compared the explanatory power of the models. Our results imply that, even when listening to short chord sequences, internally constructed and updated tonal assumptions determine the expectancy of the upcoming chord.

  5. CyanOmics: an integrated database of omics for the model cyanobacterium Synechococcus sp. PCC 7002

    OpenAIRE

    Yang, Yaohua; Feng, Jie; Li, Tao; Ge, Feng; Zhao, Jindong

    2015-01-01

    Cyanobacteria are an important group of organisms that carry out oxygenic photosynthesis and play vital roles in both the carbon and nitrogen cycles of the Earth. The annotated genome of Synechococcus sp. PCC 7002, as an ideal model cyanobacterium, is available. A series of transcriptomic and proteomic studies of Synechococcus sp. PCC 7002 cells grown under different conditions have been reported. However, no database of such integrated omics studies has been constructed. Here we present Cyan...

  6. Development of a clinical prediction model to calculate patient life expectancy: the measure of actuarial life expectancy (MALE).

    Science.gov (United States)

    Clarke, M G; Kennedy, K P; MacDonagh, R P

    2009-01-01

    To develop a clinical prediction model enabling the calculation of an individual patient's life expectancy (LE) and survival probability based on age, sex, and comorbidity for use in the joint decision-making process regarding medical treatment. A computer software program was developed with a team of 3 clinicians, 2 professional actuaries, and 2 professional computer programmers. This incorporated statistical spreadsheet and database access design methods. Data sources included life insurance industry actuarial rating factor tables (public and private domain), Government Actuary Department UK life tables, professional actuarial sources, and evidence-based medical literature. The main outcome measures were numerical and graphical display of comorbidity-adjusted LE; 5-, 10-, and 15-year survival probability; in addition to generic UK population LE. Nineteen medical conditions, which impacted significantly on LE in actuarial terms and were commonly encountered in clinical practice, were incorporated in the final model. Numerical and graphical representations of statistical predictions of LE and survival probability were successfully generated for patients with either no comorbidity or a combination of the 19 medical conditions included. Validation and testing, including actuarial peer review, confirmed consistency with the data sources utilized. The evidence-based actuarial data utilized in this computer program design represent a valuable resource for use in the clinical decision-making process, where an accurate objective assessment of patient LE can so often make the difference between patients being offered or denied medical and surgical treatment. Ongoing development to incorporate additional comorbidities and enable Web-based access will enhance its use further.

  7. Modeling radiative transport in ICF plasmas on an IBM SP2 supercomputer

    International Nuclear Information System (INIS)

    Johansen, J.A.; MacFarlane, J.J.; Moses, G.A.

    1995-01-01

    At the University of Wisconsin-Madison the authors have integrated a collisional-radiative-equilibrium model into their CONRAD radiation-hydrodynamics code. This integrated package allows them to accurately simulate the transport processes involved in ICF plasmas; including the important effects of self-absorption of line-radiation. However, as they increase the amount of atomic structure utilized in their transport models, the computational demands increase nonlinearly. In an attempt to meet this increased computational demand, they have recently embarked on a mission to parallelize the CONRAD program. The parallel CONRAD development is being performed on an IBM SP2 supercomputer. The parallelism is based on a message passing paradigm, and is being implemented using PVM. At the present time they have determined that approximately 70% of the sequential program can be executed in parallel. Accordingly, they expect that the parallel version will yield a speedup on the order of three times that of the sequential version. This translates into only 10 hours of execution time for the parallel version, whereas the sequential version required 30 hours

  8. Corroboration of the J-value model for life-expectancy growth in industrialised countries

    OpenAIRE

    Thomas, Philip

    2017-01-01

    After including an allowance for the gap between male and female life expectancies at birth diminishing over the past 50 years in industrialized countries, the J-value model incorporating “male catch-up” has been validated against actual UK data on life expectancy. A close correspondence has also been found between forecasts for life expectancy at birth in 35 countries made by the J-value model and those produced in a recent study that applied Bayesian model averaging to 21 demographic projec...

  9. A "Uses and Gratification Expectancy Model" to Predict Students' "Perceived e-Learning Experience"

    Science.gov (United States)

    Mondi, Makingu; Woods, Peter; Rafi, Ahmad

    2008-01-01

    This study investigates "how and why" students' "Uses and Gratification Expectancy" (UGE) for e-learning resources influences their "Perceived e-Learning Experience." A "Uses and Gratification Expectancy Model" (UGEM) framework is proposed to predict students' "Perceived e-Learning Experience," and…

  10. Attachment, Working Models of Parenting, and Expectations for Using Television in Childrearing

    Science.gov (United States)

    Nathanson, Amy I.; Manohar, Uttara

    2012-01-01

    This study used attachment theory to understand college students' working models of parenting and expectations for how they would use television in parenting. We found that secure parent-child attachment histories were related to more positive expectations of parenting and that avoidant and anxious-ambivalent parent-child attachment histories were…

  11. Cost Perception and the Expectancy-Value Model of Achievement Motivation.

    Science.gov (United States)

    Anderson, Patricia N.

    The expectancy-value model of achievement motivation, first described by J. Atkinson (1957) and refined by J. Eccles and her colleagues (1983, 1992, 1994) predicts achievement motivation based on expectancy for success and perceived task value. Cost has been explored very little. To explore the possibility that cost is different from expectancy…

  12. College Students' Motivation toward Weight Training: An Application of Expectancy-Value Model

    Science.gov (United States)

    Gao, Zan; Xiang, Ping

    2008-01-01

    Guided by an expectancy-value model of achievement choice (Eccles et al., 1983; Wigfield & Eccles, 2000), the relationships among expectancy-related beliefs, subjective task values (importance, interest, and usefulness), and achievement outcomes (intention, engagement, and performance) were examined in a college-level beginning weight training…

  13. Children's motivation in elementary physical education: an expectancy-value model of achievement choice.

    Science.gov (United States)

    Xiang, Ping; McBride, Ron; Guan, Jianmin; Solmon, Melinda

    2003-03-01

    This study examined children's motivation in elementary physical education within an expectancy-value model developed by Eccles and her colleagues. Four hundred fourteen students in second and fourth grades completed questionnaires assessing their expectancy-related beliefs, subjective task values, and intention for future participation in physical education. Results indicated that expectancy-related beliefs and subjective task values were clearly distinguishable from one another across physical education and throwing. The two constructs were related to each other positively. Children's intention for future participation in physical education was positively associated with their subjective task values and/or expectancy-related beliefs. Younger children had higher motivation for learning in physical education than older children. Gender differences emerged and the findings provided empirical evidence supporting the validity of the expectancy-value model in elementary physical education.

  14. On a Numerical and Graphical Technique for Evaluating some Models Involving Rational Expectations

    DEFF Research Database (Denmark)

    Johansen, Søren; Swensen, Anders Rygh

    Campbell and Shiller (1987) proposed a graphical technique for the present value model which consists of plotting the spread and theoretical spread as calculated from the cointegrated vector autoregressive model. We extend these techniques to a number of rational expectation models and give...

  15. On a numerical and graphical technique for evaluating some models involving rational expectations

    DEFF Research Database (Denmark)

    Johansen, Søren; Swensen, Anders Rygh

    Campbell and Shiller (1987) proposed a graphical technique for the present value model which consists of plotting the spread and theoretical spread as calculated from the cointegrated vector autoregressive model. We extend these techniques to a number of rational expectation models and give...

  16. Estimating model error covariances in nonlinear state-space models using Kalman smoothing and the expectation-maximisation algorithm

    KAUST Repository

    Dreano, Denis; Tandeo, P.; Pulido, M.; Ait-El-Fquih, Boujemaa; Chonavel, T.; Hoteit, Ibrahim

    2017-01-01

    Specification and tuning of errors from dynamical models are important issues in data assimilation. In this work, we propose an iterative expectation-maximisation (EM) algorithm to estimate the model error covariances using classical extended

  17. Decomposing the roles of perseveration and expected value representation in models of the Iowa gambling task.

    Science.gov (United States)

    Worthy, Darrell A; Pang, Bo; Byrne, Kaileigh A

    2013-01-01

    Models of human behavior in the Iowa Gambling Task (IGT) have played a pivotal role in accounting for behavioral differences during decision-making. One critical difference between models that have been used to account for behavior in the IGT is the inclusion or exclusion of the assumption that participants tend to persevere, or stay with the same option over consecutive trials. Models that allow for this assumption include win-stay-lose-shift (WSLS) models and reinforcement learning (RL) models that include a decay learning rule where expected values for each option decay as they are chosen less often. One shortcoming of RL models that have included decay rules is that the tendency to persevere by sticking with the same option has been conflated with the tendency to select the option with the highest expected value because a single term is used to represent both of these tendencies. In the current work we isolate the tendencies to perseverate and to select the option with the highest expected value by including them as separate terms in a Value-Plus-Perseveration (VPP) RL model. Overall the VPP model provides a better fit to data from a large group of participants than models that include a single term to account for both perseveration and the representation of expected value. Simulations of each model show that the VPP model's simulated choices most closely resemble the decision-making behavior of human subjects. In addition, we also find that parameter estimates of loss aversion are more strongly correlated with performance when perseverative tendencies and expected value representations are decomposed as separate terms within the model. The results suggest that the tendency to persevere and the tendency to select the option that leads to the best net payoff are central components of decision-making behavior in the IGT. Future work should use this model to better examine decision-making behavior.

  18. Decomposing the Roles of Perseveration and Expected Value Representation in Models of the Iowa Gambling Task

    Directory of Open Access Journals (Sweden)

    Darrell A. Worthy

    2013-09-01

    Full Text Available Models of human behavior in the Iowa Gambling Task (IGT have played a pivotal role in accounting for behavioral differences during decision-making. One critical difference between models that have been used to account for behavior in the IGT is the inclusion or exclusion of the assumption that participants tend to persevere, or stay with the same option over consecutive trials. Models that allow for this assumption include win-stay-lose-shift (WSLS models and reinforcement learning (RL models that include a decay learning rule where expected values for each option decay as they are chosen less often. One shortcoming of RL models that have included decay rules is that the tendency to persevere by sticking with the same option has been conflated with the tendency to select the option with the highest expected value because a single term is used to represent both of these tendencies. In the current work we isolate the tendencies to perseverate and to select the option with the highest expected value by including them as separate terms in a Value-Plus-Perseveration (VPP RL model. Overall the VPP model provides a better fit to data from a large group of participants than models that include a single term to account for both perseveration and the representation of expected value. Simulations of each model show that the VPP model’s simulated choices most closely resemble the decision-making behavior of human subjects. In addition, we also find that parameter estimates of loss aversion are more strongly correlated with performance when perseverative tendencies and expected value representations are decomposed as separate terms within the model. The results suggest that the tendency to persevere and the tendency to select the option that leads to the best net payoff are central components of decision-making behavior in the IGT. Future work should use this model to better examine decision-making behavior.

  19. USE OF VIRTUAL LEARNING ENVIRONMENTS: A THEORETICAL MODEL USING DECOMPOSED EXPECTANCY DISCONFIRMATION THEORY

    OpenAIRE

    Pereira, Fernando Antonio de Melo; Ramos, Anatália Saraiva Martins; Andrade, Adrianne Paula Vieira de; Oliveira, Bruna Miyuki Kasuya de

    2015-01-01

    ABSTRACT The present study aims to investigate the determinants of satisfaction and the resulting continuance intention in the e-learning context. The constructs of decomposed expectancy disconfirmation theory (DEDT) are evaluated from the perspective of users of a virtual learning environment (VLE) in relation to expectations and perceived performance. An online survey collected responses from 197 students of a public management distance learning course. Structural equation modeling was oper...

  20. Reinvention of publishers' revenue model: expectations of advertisers towards publishers' products

    OpenAIRE

    Koller, Hans; Dennstedt, Bianca

    2017-01-01

    Publishers have to reconsider their revenue model. Facing a massive decline in the circulation of newspapers and magazines over the past years, publishers have lost not only readers but also many advertisers. Thus, publishers are faced with both changed customer expectations as well as difficulty in generating profit. Users are increasingly less willing to pay for digital products and their expectations of digital content have changed: They would like to contribute their own content as well a...

  1. Sustainable business model adoption among S&P 500 firms : A longitudinal content analysis study

    NARCIS (Netherlands)

    Ritala, Paavo; Huotari, Pontus; Bocken, N.M.P.; Albareda, Laura; Puumalainen, Kaisu

    2018-01-01

    In this study, we examine the diversity of sustainable business models adopted by the largest global corporations — those listed in the S&P 500 index — over the period 2005–2014. We examine press release communications during this period, which represent public data about business-relevant

  2. 76 FR 36392 - Airworthiness Directives; Gulfstream Aerospace Corporation Model GV and GV-SP Airplanes

    Science.gov (United States)

    2011-06-22

    ... Aircraft Certification Office (ACO) 1701 Columbia Avenue, College Park, Georgia 30337; phone: 404-474-5566..., Atlanta Aircraft Certification Office (ACO) 1701 Columbia Avenue, College Park, Georgia 30337; telephone... Aerospace Corporation Model GV and GV-SP Airplanes AGENCY: Federal Aviation Administration (FAA), DOT...

  3. An expectancy-value model of emotion regulation: implications for motivation, emotional experience, and decision making.

    Science.gov (United States)

    Tamir, Maya; Bigman, Yochanan E; Rhodes, Emily; Salerno, James; Schreier, Jenna

    2015-02-01

    According to expectancy-value models of self-regulation, people are motivated to act in ways they expect to be useful to them. For instance, people are motivated to run when they believe running is useful, even when they have nothing to run away from. Similarly, we propose an expectancy-value model of emotion regulation, according to which people are motivated to emote in ways they expect to be useful to them, regardless of immediate contextual demands. For instance, people may be motivated to get angry when they believe anger is useful, even when there is nothing to be angry about. In 5 studies, we demonstrate that leading people to expect an emotion to be useful increased their motivation to experience that emotion (Studies 1-5), led them to up-regulate the experience of that emotion (Studies 3-4), and led to emotion-consistent behavior (Study 4). Our hypotheses were supported when we manipulated the expected value of anxiety (Study 1) and anger (Studies 2-5), both consciously (Studies 1-4) and unconsciously (Study 5). We discuss the theoretical and pragmatic implications of the proposed model. PsycINFO Database Record (c) 2015 APA, all rights reserved.

  4. A model for calculating expected performance of the Apollo unified S-band (USB) communication system

    Science.gov (United States)

    Schroeder, N. W.

    1971-01-01

    A model for calculating the expected performance of the Apollo unified S-band (USB) communication system is presented. The general organization of the Apollo USB is described. The mathematical model is reviewed and the computer program for implementation of the calculations is included.

  5. Stock Selection for Portfolios Using Expected Utility-Entropy Decision Model

    Directory of Open Access Journals (Sweden)

    Jiping Yang

    2017-09-01

    Full Text Available Yang and Qiu proposed and then recently improved an expected utility-entropy (EU-E measure of risk and decision model. When segregation holds, Luce et al. derived an expected utility term, plus a constant multiplies the Shannon entropy as the representation of risky choices, further demonstrating the reasonability of the EU-E decision model. In this paper, we apply the EU-E decision model to selecting the set of stocks to be included in the portfolios. We first select 7 and 10 stocks from the 30 component stocks of Dow Jones Industrial Average index, and then derive and compare the efficient portfolios in the mean-variance framework. The conclusions imply that efficient portfolios composed of 7(10 stocks selected using the EU-E model with intermediate intervals of the tradeoff coefficients are more efficient than that composed of the sets of stocks selected using the expected utility model. Furthermore, the efficient portfolio of 7(10 stocks selected by the EU-E decision model have almost the same efficient frontier as that of the sample of all stocks. This suggests the necessity of incorporating both the expected utility and Shannon entropy together when taking risky decisions, further demonstrating the importance of Shannon entropy as the measure of uncertainty, as well as the applicability of the EU-E model as a decision-making model.

  6. Expectancy-Value models of health behaviour: the role of salience and anticipated affect

    NARCIS (Netherlands)

    van der Pligt, J.; de Vries, N.K.

    1998-01-01

    Expectancy-value models of health behaviour are based upon the assumption that this behaviour is determined by a subjective cost-benefit analysis. Generally, these models emphasize cognitive appraisal processes focusing on the likelihood and evaluation of the consequences of health-related

  7. Disconfirming User Expectations of the Online Service Experience: Inferred versus Direct Disconfirmation Modeling.

    Science.gov (United States)

    O'Neill, Martin; Palmer, Adrian; Wright, Christine

    2003-01-01

    Disconfirmation models of online service measurement seek to define service quality as the difference between user expectations of the service to be received and perceptions of the service actually received. Two such models-inferred and direct disconfirmation-for measuring quality of the online experience are compared (WebQUAL, SERVQUAL). Findings…

  8. European Model Company Act jako nowy instrument harmonizacji europejskiego prawa spółek

    OpenAIRE

    Możdżeń, Kamila

    2016-01-01

    Przedmiotem żywej dyskusji w dziedzinie harmonizacji europejskiego prawa spółek stał się ostatnio przełomowy szkic europejskiej ustawy modelowej o spółkach - European Model Company Act (EMCA), który po kilku latach prac najwybitniejszych ekspertów z całej Europy ujrzał światło dzienne. Modelowy europejski kodeks spółek handlowych, który państwa członkowskie będą mogły dobrowolnie implementować, ma pełnić rolę obiecującego dopełnienia dotychczasowych instrumentów harmonizacyjnych oraz inspirow...

  9. Deriving the expected utility of a predictive model when the utilities are uncertain.

    Science.gov (United States)

    Cooper, Gregory F; Visweswaran, Shyam

    2005-01-01

    Predictive models are often constructed from clinical databases with the goal of eventually helping make better clinical decisions. Evaluating models using decision theory is therefore natural. When constructing a model using statistical and machine learning methods, however, we are often uncertain about precisely how the model will be used. Thus, decision-independent measures of classification performance, such as the area under an ROC curve, are popular. As a complementary method of evaluation, we investigate techniques for deriving the expected utility of a model under uncertainty about the model's utilities. We demonstrate an example of the application of this approach to the evaluation of two models that diagnose coronary artery disease.

  10. Expectancy-Violation and Information-Theoretic Models of Melodic Complexity

    Directory of Open Access Journals (Sweden)

    Tuomas Eerola

    2016-07-01

    Full Text Available The present study assesses two types of models for melodic complexity: one based on expectancy violations and the other one related to an information-theoretic account of redundancy in music. Seven different datasets spanning artificial sequences, folk and pop songs were used to refine and assess the models. The refinement eliminated unnecessary components from both types of models. The final analysis pitted three variants of the two model types against each other and could explain from 46-74% of the variance in the ratings across the datasets. The most parsimonious models were identified with an information-theoretic criterion. This suggested that the simplified expectancy-violation models were the most efficient for these sets of data. However, the differences between all optimized models were subtle in terms both of performance and simplicity.

  11. Binomial model for measuring expected credit losses from trade receivables in non-financial sector entities

    Directory of Open Access Journals (Sweden)

    Branka Remenarić

    2018-01-01

    Full Text Available In July 2014, the International Accounting Standards Board (IASB published International Financial Reporting Standard 9 Financial Instruments (IFRS 9. This standard introduces an expected credit loss (ECL impairment model that applies to financial instruments, including trade and lease receivables. IFRS 9 applies to annual periods beginning on or after 1 January 2018 in the European Union member states. While the main reason for amending the current model was to require major banks to recognize losses in advance of a credit event occurring, this new model also applies to all receivables, including trade receivables, lease receivables, related party loan receivables in non-financial sector entities. The new impairment model is intended to result in earlier recognition of credit losses. The previous model described in International Accounting Standard 39 Financial instruments (IAS 39 was based on incurred losses. One of the major questions now is what models to use to predict expected credit losses in non-financial sector entities. The purpose of this paper is to research the application of the current impairment model, the extent to which the current impairment model can be modified to satisfy new impairment model requirements and the applicability of the binomial model for measuring expected credit losses from accounts receivable.

  12. Long-term medical costs and life expectancy of acute myeloid leukemia: a probabilistic decision model.

    Science.gov (United States)

    Wang, Han-I; Aas, Eline; Howell, Debra; Roman, Eve; Patmore, Russell; Jack, Andrew; Smith, Alexandra

    2014-03-01

    Acute myeloid leukemia (AML) can be diagnosed at any age and treatment, which can be given with supportive and/or curative intent, is considered expensive compared with that for other cancers. Despite this, no long-term predictive models have been developed for AML, mainly because of the complexities associated with this disease. The objective of the current study was to develop a model (based on a UK cohort) to predict cost and life expectancy at a population level. The model developed in this study combined a decision tree with several Markov models to reflect the complexity of the prognostic factors and treatments of AML. The model was simulated with a cycle length of 1 month for a time period of 5 years and further simulated until age 100 years or death. Results were compared for two age groups and five different initial treatment intents and responses. Transition probabilities, life expectancies, and costs were derived from a UK population-based specialist registry-the Haematological Malignancy Research Network (www.hmrn.org). Overall, expected 5-year medical costs and life expectancy ranged from £8,170 to £81,636 and 3.03 to 34.74 months, respectively. The economic and health outcomes varied with initial treatment intent, age at diagnosis, trial participation, and study time horizon. The model was validated by using face, internal, and external validation methods. The results show that the model captured more than 90% of the empirical costs, and it demonstrated good fit with the empirical overall survival. Costs and life expectancy of AML varied with patient characteristics and initial treatment intent. The robust AML model developed in this study could be used to evaluate new diagnostic tools/treatments, as well as enable policy makers to make informed decisions. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  13. Kinetic study and modeling of biosurfactant production using Bacillus sp.

    Directory of Open Access Journals (Sweden)

    Hesty Heryani

    2017-05-01

    Conclusions: For further development and industrial applications, the modified Gompertz equation is proposed to predict the cell mass and biosurfactant production as a goodness of fit was obtained with this model. The modified Gompertz equation was also extended to enable the excellent prediction of the surface tension.

  14. Frequency-domain optical tomographic image reconstruction algorithm with the simplified spherical harmonics (SP3) light propagation model.

    Science.gov (United States)

    Kim, Hyun Keol; Montejo, Ludguier D; Jia, Jingfei; Hielscher, Andreas H

    2017-06-01

    We introduce here the finite volume formulation of the frequency-domain simplified spherical harmonics model with n -th order absorption coefficients (FD-SP N ) that approximates the frequency-domain equation of radiative transfer (FD-ERT). We then present the FD-SP N based reconstruction algorithm that recovers absorption and scattering coefficients in biological tissue. The FD-SP N model with 3 rd order absorption coefficient (i.e., FD-SP 3 ) is used as a forward model to solve the inverse problem. The FD-SP 3 is discretized with a node-centered finite volume scheme and solved with a restarted generalized minimum residual (GMRES) algorithm. The absorption and scattering coefficients are retrieved using a limited-memory Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) algorithm. Finally, the forward and inverse algorithms are evaluated using numerical phantoms with optical properties and size that mimic small-volume tissue such as finger joints and small animals. The forward results show that the FD-SP 3 model approximates the FD-ERT (S 12 ) solution within relatively high accuracy; the average error in the phase (<3.7%) and the amplitude (<7.1%) of the partial current at the boundary are reported. From the inverse results we find that the absorption and scattering coefficient maps are more accurately reconstructed with the SP 3 model than those with the SP 1 model. Therefore, this work shows that the FD-SP 3 is an efficient model for optical tomographic imaging of small-volume media with non-diffuse properties both in terms of computational time and accuracy as it requires significantly lower CPU time than the FD-ERT (S 12 ) and also it is more accurate than the FD-SP 1 .

  15. Parameter estimation of Monod model by the Least-Squares method for microalgae Botryococcus Braunii sp

    Science.gov (United States)

    See, J. J.; Jamaian, S. S.; Salleh, R. M.; Nor, M. E.; Aman, F.

    2018-04-01

    This research aims to estimate the parameters of Monod model of microalgae Botryococcus Braunii sp growth by the Least-Squares method. Monod equation is a non-linear equation which can be transformed into a linear equation form and it is solved by implementing the Least-Squares linear regression method. Meanwhile, Gauss-Newton method is an alternative method to solve the non-linear Least-Squares problem with the aim to obtain the parameters value of Monod model by minimizing the sum of square error ( SSE). As the result, the parameters of the Monod model for microalgae Botryococcus Braunii sp can be estimated by the Least-Squares method. However, the estimated parameters value obtained by the non-linear Least-Squares method are more accurate compared to the linear Least-Squares method since the SSE of the non-linear Least-Squares method is less than the linear Least-Squares method.

  16. Exact expectation values of local fields in the quantum sine-Gordon model

    International Nuclear Information System (INIS)

    Lukyanov, S.; Rossijskaya Akademiya Nauk, Chernogolovka; Zamolodchikov, A.; Rossijskaya Akademiya Nauk, Chernogolovka

    1997-01-01

    We propose an explicit expression for vacuum expectation values left angle e iaφ right angle of the exponential fields in the sine-Gordon model. Our expression agrees both with semi-classical results in the sine-Gordon theory and with perturbative calculations in the massive Thirring model. We use this expression to make new predictions about the large-distance asymptotic form of the two-point correlation function in the XXZ spin chain. (orig.)

  17. The impossibility of involuntary unemployment in an overlapping generations model with rational expectation

    DEFF Research Database (Denmark)

    Schultz, Christian

    1992-01-01

    If there is unemployment no matter how low the wage rate becomes, one speaks of involuntary unemployment. This phenomenon has been shown to arise in a variety of temporary or atemporal macro models with imperfect competition in the goods markets. In this paper we investigate whether the phenomeno...... of involuntary unemployment arises in a Hartian overlapping generations model with rational expectations. It does not, neither in the short nor in the long run...

  18. CyanOmics: an integrated database of omics for the model cyanobacterium Synechococcus sp. PCC 7002.

    Science.gov (United States)

    Yang, Yaohua; Feng, Jie; Li, Tao; Ge, Feng; Zhao, Jindong

    2015-01-01

    Cyanobacteria are an important group of organisms that carry out oxygenic photosynthesis and play vital roles in both the carbon and nitrogen cycles of the Earth. The annotated genome of Synechococcus sp. PCC 7002, as an ideal model cyanobacterium, is available. A series of transcriptomic and proteomic studies of Synechococcus sp. PCC 7002 cells grown under different conditions have been reported. However, no database of such integrated omics studies has been constructed. Here we present CyanOmics, a database based on the results of Synechococcus sp. PCC 7002 omics studies. CyanOmics comprises one genomic dataset, 29 transcriptomic datasets and one proteomic dataset and should prove useful for systematic and comprehensive analysis of all those data. Powerful browsing and searching tools are integrated to help users directly access information of interest with enhanced visualization of the analytical results. Furthermore, Blast is included for sequence-based similarity searching and Cluster 3.0, as well as the R hclust function is provided for cluster analyses, to increase CyanOmics's usefulness. To the best of our knowledge, it is the first integrated omics analysis database for cyanobacteria. This database should further understanding of the transcriptional patterns, and proteomic profiling of Synechococcus sp. PCC 7002 and other cyanobacteria. Additionally, the entire database framework is applicable to any sequenced prokaryotic genome and could be applied to other integrated omics analysis projects. Database URL: http://lag.ihb.ac.cn/cyanomics. © The Author(s) 2015. Published by Oxford University Press.

  19. Why environmental and resource economists should care about non-expected utility models

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, W. Douglass; Woodward, Richard T. [Department of Agricultural Economics, Texas A and M University (United States)

    2008-01-15

    Experimental and theoretical analysis has shown that the conventional expected utility (EU) and subjective expected utility (SEU) models, which are linear in probabilities, have serious limitations in certain situations. We argue here that these limitations are often highly relevant to the work that environmental and natural resource economists do. We discuss some of the experimental evidence and alternatives to the SEU. We consider the theory used, the problems studied, and the methods employed by resource economists. Finally, we highlight some recent work that has begun to use some of the alternatives to the EU and SEU frameworks and discuss areas where much future work is needed. (author)

  20. A Model to Explain the Emergence of Reward Expectancy neurons using Reinforcement Learning and Neural Network

    OpenAIRE

    Shinya, Ishii; Munetaka, Shidara; Katsunari, Shibata

    2006-01-01

    In an experiment of multi-trial task to obtain a reward, reward expectancy neurons,###which responded only in the non-reward trials that are necessary to advance###toward the reward, have been observed in the anterior cingulate cortex of monkeys.###In this paper, to explain the emergence of the reward expectancy neuron in###terms of reinforcement learning theory, a model that consists of a recurrent neural###network trained based on reinforcement learning is proposed. The analysis of the###hi...

  1. Expected utility and catastrophic risk in a stochastic economy-climate model

    Energy Technology Data Exchange (ETDEWEB)

    Ikefuji, M. [Institute of Social and Economic Research, Osaka University, Osaka (Japan); Laeven, R.J.A.; Magnus, J.R. [Department of Econometrics and Operations Research, Tilburg University, Tilburg (Netherlands); Muris, C. [CentER, Tilburg University, Tilburg (Netherlands)

    2010-11-15

    In the context of extreme climate change, we ask how to conduct expected utility analysis in the presence of catastrophic risks. Economists typically model decision making under risk and uncertainty by expected utility with constant relative risk aversion (power utility); statisticians typically model economic catastrophes by probability distributions with heavy tails. Unfortunately, the expected utility framework is fragile with respect to heavy-tailed distributional assumptions. We specify a stochastic economy-climate model with power utility and explicitly demonstrate this fragility. We derive necessary and sufficient compatibility conditions on the utility function to avoid fragility and solve our stochastic economy-climate model for two examples of such compatible utility functions. We further develop and implement a procedure to learn the input parameters of our model and show that the model thus specified produces quite robust optimal policies. The numerical results indicate that higher levels of uncertainty (heavier tails) lead to less abatement and consumption, and to more investment, but this effect is not unlimited.

  2. A competing risk model for reduction in life expectancy from radiogenic cancer

    International Nuclear Information System (INIS)

    Davis, H.T.

    1978-01-01

    Latent radiogenic cancer fatalities from reactor accidents are considered to be more important than early fatalities. However, early fatalities generally result in appreciable life shortening for the affected individual whereas latent cancer fatalities generally result in limited life shortening. In this report a mathematical model is developed to express the reduction in life expectancy from radiogenic cancer as a function of dose received. The model is then used to compare the linear model of latent radiogenic cancer incidence with several nonlinear models that have appeared in the literature. (author)

  3. Deviations from tribimaximal mixing due to the vacuum expectation value misalignment in A4 models

    International Nuclear Information System (INIS)

    Barry, James; Rodejohann, Werner

    2010-01-01

    The addition of an A 4 family symmetry and extended Higgs sector to the standard model can generate the tribimaximal mixing pattern for leptons, assuming the correct vacuum expectation value alignment of the Higgs scalars. Deviating this alignment affects the predictions for the neutrino oscillation and neutrino mass observables. An attempt is made to classify the plethora of models in the literature, with respect to the chosen A 4 particle assignments. Of these models, two particularly popular examples have been analyzed for deviations from tribimaximal mixing by perturbing the vacuum expectation value alignments. The effect of perturbations on the mixing angle observables is studied. However, it is only investigation of the mass-related observables (the effective mass for neutrinoless double beta decay and the sum of masses from cosmology) that can lead to the exclusion of particular models by constraints from future data, which indicates the importance of neutrino mass in disentangling models. The models have also been tested for fine-tuning of the parameters. Furthermore, a well-known seesaw model is generalized to include additional scalars, which transform as representations of A 4 not included in the original model.

  4. Integrating technology readiness into the expectation-confirmation model: an empirical study of mobile services.

    Science.gov (United States)

    Chen, Shih-Chih; Liu, Ming-Ling; Lin, Chieh-Peng

    2013-08-01

    The aim of this study was to integrate technology readiness into the expectation-confirmation model (ECM) for explaining individuals' continuance of mobile data service usage. After reviewing the ECM and technology readiness, an integrated model was demonstrated via empirical data. Compared with the original ECM, the findings of this study show that the integrated model may offer an ameliorated way to clarify what factors and how they influence the continuous intention toward mobile services. Finally, the major findings are summarized, and future research directions are suggested.

  5. Proposal for intake model for workers at IPEN-CNEN/SP who handle 131 I

    International Nuclear Information System (INIS)

    Todo, A.S.; Potiens Junior, A.J.; Gaburo, J.C.; Sanches, M.P.; Oliveira, E.M.

    1997-01-01

    The intake model for the two groups of workers at IPEN-CNEN/SP is presented. They handle iodine compounds during the processing of irradiated targets and at labeling of radiopharmaceutical compounds. The intake model for the workers are proposed from the knowledge of the activities carried out in the plant and the internal monitoring program of the workers. In this study, the intake is considered to be taken uniformly during the days of major activities carried out by the workers. In practice, the application of this model has be shown suitable, for the studied groups

  6. Time Series Modeling of Nano-Gold Immunochromatographic Assay via Expectation Maximization Algorithm.

    Science.gov (United States)

    Zeng, Nianyin; Wang, Zidong; Li, Yurong; Du, Min; Cao, Jie; Liu, Xiaohui

    2013-12-01

    In this paper, the expectation maximization (EM) algorithm is applied to the modeling of the nano-gold immunochromatographic assay (nano-GICA) via available time series of the measured signal intensities of the test and control lines. The model for the nano-GICA is developed as the stochastic dynamic model that consists of a first-order autoregressive stochastic dynamic process and a noisy measurement. By using the EM algorithm, the model parameters, the actual signal intensities of the test and control lines, as well as the noise intensity can be identified simultaneously. Three different time series data sets concerning the target concentrations are employed to demonstrate the effectiveness of the introduced algorithm. Several indices are also proposed to evaluate the inferred models. It is shown that the model fits the data very well.

  7. GGRaSP: A R-package for selecting representative genomes using Gaussian mixture models.

    Science.gov (United States)

    Clarke, Thomas H; Brinkac, Lauren M; Sutton, Granger; Fouts, Derrick E

    2018-04-14

    The vast number of available sequenced bacterial genomes occasionally exceeds the facilities of comparative genomic methods or is dominated by a single outbreak strain, and thus a diverse and representative subset is required. Generation of the reduced subset currently requires a priori supervised clustering and sequence-only selection of medoid genomic sequences, independent of any additional genome metrics or strain attributes. The GGRaSP R-package described below generates a reduced subset of genomes that prioritizes maintaining genomes of interest to the user as well as minimizing the loss of genetic variation. The package also allows for unsupervised clustering by modeling the genomic relationships using a Gaussian Mixture Model to select an appropriate cluster threshold. We demonstrate the capabilities of GGRaSP by generating a reduced list of 315 genomes from a genomic dataset of 4600 Escherichia coli genomes, prioritizing selection by type strain and by genome completeness. GGRaSP is available at https://github.com/JCVenterInstitute/ggrasp/. tclarke@jcvi.org. Supplementary data are available at the GitHub site.

  8. Models of expected returns on the brazilian market: Empirical tests using predictive methodology

    Directory of Open Access Journals (Sweden)

    Adriano Mussa

    2009-01-01

    Full Text Available Predictive methodologies for test of the expected returns models are largely diffused on the international academic environment. However, these methods have not been used in Brazil in a systematic way. Generally, empirical studies proceeded with Brazilian stock market data are concentrated only in the first step of these methodologies. The purpose of this article was test and compare the models CAPM, 3-factors and 4-factors using a predictive methodology, considering two steps – temporal and cross-section regressions – with standard errors obtained by the techniques of Fama and Macbeth (1973. The results indicated the superiority of the 4-fators model as compared to the 3-fators model, and the superiority of the 3- factors model as compared to the CAPM, but no one of the tested models were enough on the explanation of the Brazilian stock returns. Contrary to some empirical evidences, that do not use predictive methodology, the size and momentum effect seem do not exist on the Brazilian capital markets, but there are evidences of the value effect and the relevance of the market for explanation of expected returns. These finds rise some questions, mainly caused by the originality of the methodology on the local market and by the fact that this subject is still incipient and polemic on the Brazilian academic environment.

  9. Analysis of dynamic Cournot learning models for generation companies based on conjectural variations and forward expectation

    International Nuclear Information System (INIS)

    Gutierrez-Alcaraz, G.; Tovar-Hernandez, Jose H.; Moreno-Goytia, Edgar L.

    2009-01-01

    Electricity spot markets generally operate on an hourly basis; under this condition GENCOs can closely observe their competitors' market behavior. For this purposes, a detailed dynamic model is one of the tools used by GENCOs to understand the behavioral variations of competitors over time. The required abilities to rapidly adjust one's own decision-making create a need for new learning procedures and models. Conjectural variations (CV) have been proposed as a learning approach. In this paper a model based on forward expectations (FE) is proposed as a learning approach, and through illustrative examples it is shown that the market equilibria found by the CV model are also obtained by the FE model. (author)

  10. Vacuum Expectation Value Profiles of the Bulk Scalar Field in the Generalized Randall-Sundrum Model

    International Nuclear Information System (INIS)

    Moazzen, M.; Tofighi, A.; Farokhtabar, A.

    2015-01-01

    In the generalized Randall-Sundrum warped brane-world model the cosmological constant induced on the visible brane can be positive or negative. In this paper we investigate profiles of vacuum expectation value of the bulk scalar field under general Dirichlet and Neumann boundary conditions in the generalized warped brane-world model. We show that the VEV profiles generally depend on the value of the brane cosmological constant. We find that the VEV profiles of the bulk scalar field for a visible brane with negative cosmological constant and positive tension are quite distinct from those of Randall-Sundrum model. In addition we show that the VEV profiles for a visible brane with large positive cosmological constant are also different from those of the Randall-Sundrum model. We also verify that Goldberger and Wise mechanism can work under nonzero Dirichlet boundary conditions in the generalized Randall-Sundrum model.

  11. Expectation Maximization Algorithm for Box-Cox Transformation Cure Rate Model and Assessment of Model Misspecification Under Weibull Lifetimes.

    Science.gov (United States)

    Pal, Suvra; Balakrishnan, Narayanaswamy

    2018-05-01

    In this paper, we develop likelihood inference based on the expectation maximization algorithm for the Box-Cox transformation cure rate model assuming the lifetimes to follow a Weibull distribution. A simulation study is carried out to demonstrate the performance of the proposed estimation method. Through Monte Carlo simulations, we also study the effect of model misspecification on the estimate of cure rate. Finally, we analyze a well-known data on melanoma with the model and the inferential method developed here.

  12. Bioremediation in fractured rock: 1. Modeling to inform design, monitoring, and expectations

    Science.gov (United States)

    Tiedeman, Claire; Shapiro, Allen M.; Hsieh, Paul A.; Imbrigiotta, Thomas; Goode, Daniel J.; Lacombe, Pierre; DeFlaun, Mary F.; Drew, Scott R.; Johnson, Carole D.; Williams, John H.; Curtis, Gary P.

    2018-01-01

    Field characterization of a trichloroethene (TCE) source area in fractured mudstones produced a detailed understanding of the geology, contaminant distribution in fractures and the rock matrix, and hydraulic and transport properties. Groundwater flow and chemical transport modeling that synthesized the field characterization information proved critical for designing bioremediation of the source area. The planned bioremediation involved injecting emulsified vegetable oil and bacteria to enhance the naturally occurring biodegradation of TCE. The flow and transport modeling showed that injection will spread amendments widely over a zone of lower‐permeability fractures, with long residence times expected because of small velocities after injection and sorption of emulsified vegetable oil onto solids. Amendments transported out of this zone will be diluted by groundwater flux from other areas, limiting bioremediation effectiveness downgradient. At nearby pumping wells, further dilution is expected to make bioremediation effects undetectable in the pumped water. The results emphasize that in fracture‐dominated flow regimes, the extent of injected amendments cannot be conceptualized using simple homogeneous models of groundwater flow commonly adopted to design injections in unconsolidated porous media (e.g., radial diverging or dipole flow regimes). Instead, it is important to synthesize site characterization information using a groundwater flow model that includes discrete features representing high‐ and low‐permeability fractures. This type of model accounts for the highly heterogeneous hydraulic conductivity and groundwater fluxes in fractured‐rock aquifers, and facilitates designing injection strategies that target specific volumes of the aquifer and maximize the distribution of amendments over these volumes.

  13. SDG fermion-pair algebraic SO(12) and Sp(10) models and their boson realizations

    International Nuclear Information System (INIS)

    Navatil, P.; Geyer, H.B.; Dobes, J.

    1995-01-01

    It is shown how the boson mapping formalism may be applied as a useful many-body tool to solve a fermion problem. This is done in the context of generalized Ginocchio models for which the authors introduce S-, D-, and G-pairs of fermions and subsequently construct the sdg-boson realizations of the generalized Dyson type. The constructed SO(12) and Sp(10) fermion models are solved beyond the explicit symmetry limits. Phase transitions to rotational structures are obtained also in situations where there is no underlying SU(3) symmetry. 34 refs., 5 figs., 2 tabs

  14. SDG Fermion-Pair Algebraic SO(12) and Sp(10) Models and Their Boson Realizations

    Science.gov (United States)

    Navratil, P.; Geyer, H. B.; Dobes, J.; Dobaczewski, J.

    1995-11-01

    It is shown how the boson mapping formalism may be applied as a useful many-body tool to solve a fermion problem. This is done in the context of generalized Ginocchio models for which we introduce S-, D-, and G-pairs of fermions and subsequently construct the sdg-boson realizations of the generalized Dyson type. The constructed SO(12) and Sp(10) fermion models are solved beyond the explicit symmetry limits. Phase transitions to rotational structures are obtained also in situations where there is no underlying SU(3) symmetry.

  15. Understanding Students' Motivation in Sport and Physical Education: From the Expectancy-Value Model and Self-Efficacy Theory Perspectives

    Science.gov (United States)

    Gao, Zan; Lee, Amelia M.; Harrison, Louis, Jr.

    2008-01-01

    In this article, the roles of individuals' expectancy beliefs and incentives (i.e., task value, outcome expectancy) in sport and physical education are examined from expectancy-value model and self-efficacy theory perspectives. Overviews of the two theoretical frameworks and the conceptual and measurement issues are provided, followed by a review…

  16. Applying an expectancy-value model to study motivators for work-task based information seeking

    DEFF Research Database (Denmark)

    Sigaard, Karen Tølbøl; Skov, Mette

    2015-01-01

    on the theory of expectancy-value and on the operationalisation used when the model was first developed. Data for the analysis were collected from a sample of seven informants working as consultants in Danish municipalities. Each participant filled out a questionnaire, kept a log book for a week...... for interpersonal and internal sources increased when the task had high-value motivation or low-expectancy motivation or both. Research limitations/implications: The study is based on a relatively small sample and considers only one motivation theory. This should be addressed in future research along...... with a broadening of the studied group to involve other professions than municipality consultants. Originality/value: Motivational theories from the field of psychology have been used sparsely in studies of information seeking. This study operationalises and verifies such a theory based on a theoretical adaptation...

  17. Improved Expectation Maximization Algorithm for Gaussian Mixed Model Using the Kernel Method

    Directory of Open Access Journals (Sweden)

    Mohd Izhan Mohd Yusoff

    2013-01-01

    Full Text Available Fraud activities have contributed to heavy losses suffered by telecommunication companies. In this paper, we attempt to use Gaussian mixed model, which is a probabilistic model normally used in speech recognition to identify fraud calls in the telecommunication industry. We look at several issues encountered when calculating the maximum likelihood estimates of the Gaussian mixed model using an Expectation Maximization algorithm. Firstly, we look at a mechanism for the determination of the initial number of Gaussian components and the choice of the initial values of the algorithm using the kernel method. We show via simulation that the technique improves the performance of the algorithm. Secondly, we developed a procedure for determining the order of the Gaussian mixed model using the log-likelihood function and the Akaike information criteria. Finally, for illustration, we apply the improved algorithm to real telecommunication data. The modified method will pave the way to introduce a comprehensive method for detecting fraud calls in future work.

  18. Models for S&P500 Dynamics: Evidence from Realized Volatility, Daily Returns, and Option Prices

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Mimouni, Karim

    in the search for alternative specifications. We then estimate the models using maximum likelihood on S&P500 returns. Finally, we employ nonlinear least squares on a panel of option data. In comparison with earlier studies that explicitly solve the filtering problem, we analyze a more comprehensive option data......Most recent empirical option valuation studies build on the affine square root (SQR) stochastic volatility model. The SQR model is a convenient choice, because it yields closed-form solutions for option prices. However, relatively little is known about the resulting biases. We investigate...... alternatives to the SQR model, by comparing its empirical performance with that of five different but equally parsimonious stochastic volatility models. We provide empirical evidence from three different sources. We first use realized volatilities to assess the properties of the SQR model and to guide us...

  19. Expected Shannon Entropy and Shannon Differentiation between Subpopulations for Neutral Genes under the Finite Island Model.

    Science.gov (United States)

    Chao, Anne; Jost, Lou; Hsieh, T C; Ma, K H; Sherwin, William B; Rollins, Lee Ann

    2015-01-01

    Shannon entropy H and related measures are increasingly used in molecular ecology and population genetics because (1) unlike measures based on heterozygosity or allele number, these measures weigh alleles in proportion to their population fraction, thus capturing a previously-ignored aspect of allele frequency distributions that may be important in many applications; (2) these measures connect directly to the rich predictive mathematics of information theory; (3) Shannon entropy is completely additive and has an explicitly hierarchical nature; and (4) Shannon entropy-based differentiation measures obey strong monotonicity properties that heterozygosity-based measures lack. We derive simple new expressions for the expected values of the Shannon entropy of the equilibrium allele distribution at a neutral locus in a single isolated population under two models of mutation: the infinite allele model and the stepwise mutation model. Surprisingly, this complex stochastic system for each model has an entropy expressable as a simple combination of well-known mathematical functions. Moreover, entropy- and heterozygosity-based measures for each model are linked by simple relationships that are shown by simulations to be approximately valid even far from equilibrium. We also identify a bridge between the two models of mutation. We apply our approach to subdivided populations which follow the finite island model, obtaining the Shannon entropy of the equilibrium allele distributions of the subpopulations and of the total population. We also derive the expected mutual information and normalized mutual information ("Shannon differentiation") between subpopulations at equilibrium, and identify the model parameters that determine them. We apply our measures to data from the common starling (Sturnus vulgaris) in Australia. Our measures provide a test for neutrality that is robust to violations of equilibrium assumptions, as verified on real world data from starlings.

  20. Expected Shannon Entropy and Shannon Differentiation between Subpopulations for Neutral Genes under the Finite Island Model.

    Directory of Open Access Journals (Sweden)

    Anne Chao

    Full Text Available Shannon entropy H and related measures are increasingly used in molecular ecology and population genetics because (1 unlike measures based on heterozygosity or allele number, these measures weigh alleles in proportion to their population fraction, thus capturing a previously-ignored aspect of allele frequency distributions that may be important in many applications; (2 these measures connect directly to the rich predictive mathematics of information theory; (3 Shannon entropy is completely additive and has an explicitly hierarchical nature; and (4 Shannon entropy-based differentiation measures obey strong monotonicity properties that heterozygosity-based measures lack. We derive simple new expressions for the expected values of the Shannon entropy of the equilibrium allele distribution at a neutral locus in a single isolated population under two models of mutation: the infinite allele model and the stepwise mutation model. Surprisingly, this complex stochastic system for each model has an entropy expressable as a simple combination of well-known mathematical functions. Moreover, entropy- and heterozygosity-based measures for each model are linked by simple relationships that are shown by simulations to be approximately valid even far from equilibrium. We also identify a bridge between the two models of mutation. We apply our approach to subdivided populations which follow the finite island model, obtaining the Shannon entropy of the equilibrium allele distributions of the subpopulations and of the total population. We also derive the expected mutual information and normalized mutual information ("Shannon differentiation" between subpopulations at equilibrium, and identify the model parameters that determine them. We apply our measures to data from the common starling (Sturnus vulgaris in Australia. Our measures provide a test for neutrality that is robust to violations of equilibrium assumptions, as verified on real world data from starlings.

  1. A model for spatial variations in life expectancy; mortality in Chinese regions in 2000

    Directory of Open Access Journals (Sweden)

    Congdon Peter

    2007-05-01

    Full Text Available Abstract Background Life expectancy in China has been improving markedly but health gains have been uneven and there is inequality in survival chances between regions and in rural as against urban areas. This paper applies a statistical modelling approach to mortality data collected in conjunction with the 2000 Census to formally assess spatial mortality contrasts in China. The modelling approach provides interpretable summary parameters (e.g. the relative mortality risk in rural as against urban areas and is more parsimonious in terms of parameters than the conventional life table model. Results Predictive fit is assessed both globally and at the level of individual five year age groups. A proportional model (age and area effects independent has a worse fit than one allowing age-area interactions following a bilinear form. The best fit is obtained by allowing for child and oldest age mortality rates to vary spatially. Conclusion There is evidence that age (21 age groups and area (31 Chinese administrative divisions are not proportional (i.e. independent mortality risk factors. In fact, spatial contrasts are greatest at young ages. There is a pronounced rural survival disadvantage, and large differences in life expectancy between provinces.

  2. Sandmeier model based topographic correction to lunar spectral profiler (SP) data from KAGUYA satellite.

    Science.gov (United States)

    Chen, Sheng-Bo; Wang, Jing-Ran; Guo, Peng-Ju; Wang, Ming-Chang

    2014-09-01

    The Moon may be considered as the frontier base for the deep space exploration. The spectral analysis is one of the key techniques to determine the lunar surface rock and mineral compositions. But the lunar topographic relief is more remarkable than that of the Earth. It is necessary to conduct the topographic correction for lunar spectral data before they are used to retrieve the compositions. In the present paper, a lunar Sandmeier model was proposed by considering the radiance effect from the macro and ambient topographic relief. And the reflectance correction model was also reduced based on the Sandmeier model. The Spectral Profile (SP) data from KAGUYA satellite in the Sinus Iridum quadrangle was taken as an example. And the digital elevation data from Lunar Orbiter Laser Altimeter are used to calculate the slope, aspect, incidence and emergence angles, and terrain-viewing factor for the topographic correction Thus, the lunar surface reflectance from the SP data was corrected by the proposed model after the direct component of irradiance on a horizontal surface was derived. As a result, the high spectral reflectance facing the sun is decreased and low spectral reflectance back to the sun is compensated. The statistical histogram of reflectance-corrected pixel numbers presents Gaussian distribution Therefore, the model is robust to correct lunar topographic effect and estimate lunar surface reflectance.

  3. A mathematical model for expected time to extinction of pathogenic bacteria through antibiotic

    Science.gov (United States)

    Ghosh, M. K.; Nandi, S.; Roy, P. K.

    2016-04-01

    Application of antibiotics in human system to prevent bacterial diseases like Gastritis, Ulcers, Meningitis, Pneumonia and Gonorrhea are indispensable. Antibiotics saved innumerable lives and continue to be a strong support for therapeutic application against pathogenic bacteria. In human system, bacterial diseases occur when pathogenic bacteria gets into the body and begin to reproduce and crowd out healthy bacteria. In this process, immature bacteria releases enzyme which is essential for bacterial cell-wall biosynthesis. After complete formation of cell wall, immature bacteria are converted to mature or virulent bacteria which are harmful to us during bacterial infections. Use of antibiotics as drug inhibits the bacterial cell wall formation. After application of antibiotics within body, the released bacterial enzyme binds with antibiotic molecule instead of its functional site during the cell wall synthesis in a competitive inhibition approach. As a consequence, the bacterial cell-wall formation as well as maturation process of pathogenic bacteria is halted and the disease is cured with lysis of bacterial cells. With this idea, a mathematical model has been developed in the present research investigation to review the inhibition of biosynthesis of bacterial cell wall by the application of antibiotics as drug in the light of enzyme kinetics. This approach helps to estimate the expected time to extinction of the pathogenic bacteria. Our mathematical approach based on the enzyme kinetic model for finding out expected time to extinction contributes favorable results for understanding of disease dynamics. Analytical and numerical results based on simulated findings validate our mathematical model.

  4. Digital Model-Based Engineering: Expectations, Prerequisites, and Challenges of Infusion

    Science.gov (United States)

    Hale, J. P.; Zimmerman, P.; Kukkala, G.; Guerrero, J.; Kobryn, P.; Puchek, B.; Bisconti, M.; Baldwin, C.; Mulpuri, M.

    2017-01-01

    Digital model-based engineering (DMbE) is the use of digital artifacts, digital environments, and digital tools in the performance of engineering functions. DMbE is intended to allow an organization to progress from documentation-based engineering methods to digital methods that may provide greater flexibility, agility, and efficiency. The term 'DMbE' was developed as part of an effort by the Model-Based Systems Engineering (MBSE) Infusion Task team to identify what government organizations might expect in the course of moving to or infusing MBSE into their organizations. The Task team was established by the Interagency Working Group on Engineering Complex Systems, an informal collaboration among government systems engineering organizations. This Technical Memorandum (TM) discusses the work of the MBSE Infusion Task team to date. The Task team identified prerequisites, expectations, initial challenges, and recommendations for areas of study to pursue, as well as examples of efforts already in progress. The team identified the following five expectations associated with DMbE infusion, discussed further in this TM: (1) Informed decision making through increased transparency, and greater insight. (2) Enhanced communication. (3) Increased understanding for greater flexibility/adaptability in design. (4) Increased confidence that the capability will perform as expected. (5) Increased efficiency. The team identified the following seven challenges an organization might encounter when looking to infuse DMbE: (1) Assessing value added to the organization. Not all DMbE practices will be applicable to every situation in every organization, and not all implementations will have positive results. (2) Overcoming organizational and cultural hurdles. (3) Adopting contractual practices and technical data management. (4) Redefining configuration management. The DMbE environment changes the range of configuration information to be managed to include performance and design models

  5. Deformed model Sp(4) model for studying pairing correlations in atomic nuclei

    CERN Document Server

    Georgieva, A I; Sviratcheva, K

    2002-01-01

    A fermion representation of the compact symplectic sp(4) algebra introduces a theoretical framework for describing pairing correlations in atomic nuclei. The important non-deformed and deformed subalgebras of sp sub ( sub q sub ) (4) and the corresponding reduction chains are explored for the multiple orbit problem. One realization of the u sub ( sub q sub ) (2) subalgebra is associated with the valence isospin, other reductions describe coupling between identical nucleons or proton-neutron pairs. Microscopic non-deformed and deformed Hamiltonians are expressed in terms of the generators of the sp(4) and sp sub q (4) algebras. In both cases eigenvalues of the isospin breaking Hamiltonian are fit to experimental ground state energies. The theory can be used to investigate the origin of the deformation and predict binding energies of nuclei in proton-rich regions. The q-deformation parameter changes the pairing strength and in so doing introduces a non-linear coupling into the collective degree of freedom

  6. truncSP: An R Package for Estimation of Semi-Parametric Truncated Linear Regression Models

    Directory of Open Access Journals (Sweden)

    Maria Karlsson

    2014-05-01

    Full Text Available Problems with truncated data occur in many areas, complicating estimation and inference. Regarding linear regression models, the ordinary least squares estimator is inconsistent and biased for these types of data and is therefore unsuitable for use. Alternative estimators, designed for the estimation of truncated regression models, have been developed. This paper presents the R package truncSP. The package contains functions for the estimation of semi-parametric truncated linear regression models using three different estimators: the symmetrically trimmed least squares, quadratic mode, and left truncated estimators, all of which have been shown to have good asymptotic and ?nite sample properties. The package also provides functions for the analysis of the estimated models. Data from the environmental sciences are used to illustrate the functions in the package.

  7. Modelling energy technology dynamics: methodology for adaptive expectations models with learning by doing and learning by searching

    International Nuclear Information System (INIS)

    Kouvaritakis, N.; Soria, A.; Isoard, S.

    2000-01-01

    This paper presents a module endogenising technical change which is capable of being attached to large scale energy models that follow an adaptive-expectations. The formulation includes, apart from the more classical learning by doing effects, quantitative relationships between technology performance and R and D expenditure. It even attempts to go further by partially endogenising the latter by incorporating an optimisation module describing private equipment manufacturers' R and D budget allocation in a context of risk and expectation. Having presented this module in abstract, the paper proceeds to describe how an operational version of it has been constructed and implemented inside a large-scale partial equilibrium world energy model (the POLES model). Concerning learning functions problems associated with the data are alluded to, the hybrid econometric methods used to estimate them are presented as well as the adjustments which had to be effected to ensure a smooth incorporation into the large model. In the final sections is explained the use of the model itself to generate partial foresight parameters for the determination of return expectations particularly in view of CO 2 constraints and associated carbon values. (orig.)

  8. A new car-following model for autonomous vehicles flow with mean expected velocity field

    Science.gov (United States)

    Wen-Xing, Zhu; Li-Dong, Zhang

    2018-02-01

    Due to the development of the modern scientific technology, autonomous vehicles may realize to connect with each other and share the information collected from each vehicle. An improved forward considering car-following model was proposed with mean expected velocity field to describe the autonomous vehicles flow behavior. The new model has three key parameters: adjustable sensitivity, strength factor and mean expected velocity field size. Two lemmas and one theorem were proven as criteria for judging the stability of homogeneousautonomous vehicles flow. Theoretical results show that the greater parameters means larger stability regions. A series of numerical simulations were carried out to check the stability and fundamental diagram of autonomous flow. From the numerical simulation results, the profiles, hysteresis loop and density waves of the autonomous vehicles flow were exhibited. The results show that with increased sensitivity, strength factor or field size the traffic jam was suppressed effectively which are well in accordance with the theoretical results. Moreover, the fundamental diagrams corresponding to three parameters respectively were obtained. It demonstrates that these parameters play almost the same role on traffic flux: i.e. before the critical density the bigger parameter is, the greater flux is and after the critical density, the opposite tendency is. In general, the three parameters have a great influence on the stability and jam state of the autonomous vehicles flow.

  9. Modeling the accumulation of As, Cd, Cu, Pb and Zn in grasses (Agrotis sp. and Poa sp. and stinging nettle (Urtica dioica on selected sites taking into account soil physico-chemical properties

    Directory of Open Access Journals (Sweden)

    Boshoff M.C.

    2014-07-01

    Full Text Available The effect of soil properties on the accumulation of metals in two vegetation types was evaluated at 10 sites with a wide variation in soil physicochemical properties pH, organic carbon, clay percentage , total soil metal concentration and exchangeable soil metal content. Accumulation modeling was conducted for grasses (Agrostis sp. and Poa sp. and stinging nettle (Urtica dioica.

  10. Modeling the accumulation of As, Cd, Cu, Pb and Zn in grasses (Agrotis sp. and Poa sp. and stinging nettle (Urtica dioica on selected sites taking into account soil physico-chemical properties

    Directory of Open Access Journals (Sweden)

    Boshoff M. C.

    2013-04-01

    Full Text Available The effect of soil properties on the accumulation of metals in two vegetation types was evaluated at 10 sites with a wide variation in soil physicochemical properties pH, organic carbon, clay percentage , total soil metal concentration and exchangeable soil metal content. Accumulation modeling was conducted for grasses (Agrostis sp. and Poa sp. and stinging nettle (Urtica dioica.

  11. New expected loss impairment model – a challenge for the banks in Bulgaria

    Directory of Open Access Journals (Sweden)

    Nadezhda Popova-Yosifova

    2017-05-01

    Full Text Available This article introduces some of the leading works on loan impairment published by supervisory authorities, auditing companies and researchers. It makes analysis of the impairment model on the basis of the expected credit losses introduced with the requirements of International Financial Reporting Standard (IFRS 9 Financial Instruments effective for periods beginning on or after 1 January 2018. There are a number of research works which show that the senior bankers may in some ways manage the financial result through the impairment, where it is assumed that the new impairment model will bring higher recognized losses. It also makes a comparative analysis of the announced information on the loan impairment and the preparation for the introduction of the IFRS 9 Financial Instruments requirements into the annual financial statements of the public banks in Bulgaria for the period 2013 – 2016.

  12. Variation that can be expected when using particle tracking models in connectivity studies

    Science.gov (United States)

    Hufnagl, Marc; Payne, Mark; Lacroix, Geneviève; Bolle, Loes J.; Daewel, Ute; Dickey-Collas, Mark; Gerkema, Theo; Huret, Martin; Janssen, Frank; Kreus, Markus; Pätsch, Johannes; Pohlmann, Thomas; Ruardij, Piet; Schrum, Corinna; Skogen, Morten D.; Tiessen, Meinard C. H.; Petitgas, Pierre; van Beek, Jan K. L.; van der Veer, Henk W.; Callies, Ulrich

    2017-09-01

    Hydrodynamic Ocean Circulation Models and Lagrangian particle tracking models are valuable tools e.g. in coastal ecology to identify the connectivity between offshore spawning and coastal nursery areas of commercially important fish, for risk assessment and more for defining or evaluating marine protected areas. Most studies are based on only one model and do not provide levels of uncertainty. Here this uncertainty was addressed by applying a suite of 11 North Sea models to test what variability can be expected concerning connectivity. Different notional test cases were calculated related to three important and well-studied North Sea fish species: herring (Clupea harengus), and the flatfishes sole (Solea solea) and plaice (Pleuronectes platessa). For sole and plaice we determined which fraction of particles released in the respective spawning areas would reach a coastal marine protected area. For herring we determined the fraction located in a wind park after a predefined time span. As temperature is more and more a focus especially in biological and global change studies, furthermore inter-model variability in temperatures experienced by the virtual particles was determined. The main focus was on the transport variability originating from the physical models and thus biological behavior was not included. Depending on the scenario, median experienced temperatures differed by 3 °C between years. The range between the different models in one year was comparable to this temperature range observed between modelled years. Connectivity between flatfish spawning areas and the coastal protected area was highly dependent on the release location and spawning time. No particles released in the English Channel in the sole scenario reached the protected area while up to 20% of the particles released in the plaice scenario did. Interannual trends in transport directions and connectivity rates were comparable between models but absolute values displayed high variations. Most

  13. Estimating model error covariances in nonlinear state-space models using Kalman smoothing and the expectation-maximisation algorithm

    KAUST Repository

    Dreano, Denis

    2017-04-05

    Specification and tuning of errors from dynamical models are important issues in data assimilation. In this work, we propose an iterative expectation-maximisation (EM) algorithm to estimate the model error covariances using classical extended and ensemble versions of the Kalman smoother. We show that, for additive model errors, the estimate of the error covariance converges. We also investigate other forms of model error, such as parametric or multiplicative errors. We show that additive Gaussian model error is able to compensate for non additive sources of error in the algorithms we propose. We also demonstrate the limitations of the extended version of the algorithm and recommend the use of the more robust and flexible ensemble version. This article is a proof of concept of the methodology with the Lorenz-63 attractor. We developed an open-source Python library to enable future users to apply the algorithm to their own nonlinear dynamical models.

  14. Stability and Hopf bifurcation for a business cycle model with expectation and delay

    Science.gov (United States)

    Liu, Xiangdong; Cai, Wenli; Lu, Jiajun; Wang, Yangyang

    2015-08-01

    According to rational expectation hypothesis, the government will take into account the future capital stock in the process of investment decision. By introducing anticipated capital stock into an economic model with investment delay, we construct a mixed functional differential system including delay and advanced variables. The system is converted to the one containing only delay by variable substitution. The equilibrium point of the system is obtained and its dynamical characteristics such as stability, Hopf bifurcation and its stability and direction are investigated by using the related theories of nonlinear dynamics. We carry out some numerical simulations to confirm these theoretical conclusions. The results indicate that both capital stock's anticipation and investment lag are the certain factors leading to the occurrence of cyclical fluctuations in the macroeconomic system. Moreover, the level of economic fluctuation can be dampened to some extent if investment decisions are made by the reasonable short-term forecast on capital stock.

  15. An Expectation Maximization Algorithm to Model Failure Times by Continuous-Time Markov Chains

    Directory of Open Access Journals (Sweden)

    Qihong Duan

    2010-01-01

    Full Text Available In many applications, the failure rate function may present a bathtub shape curve. In this paper, an expectation maximization algorithm is proposed to construct a suitable continuous-time Markov chain which models the failure time data by the first time reaching the absorbing state. Assume that a system is described by methods of supplementary variables, the device of stage, and so on. Given a data set, the maximum likelihood estimators of the initial distribution and the infinitesimal transition rates of the Markov chain can be obtained by our novel algorithm. Suppose that there are m transient states in the system and that there are n failure time data. The devised algorithm only needs to compute the exponential of m×m upper triangular matrices for O(nm2 times in each iteration. Finally, the algorithm is applied to two real data sets, which indicates the practicality and efficiency of our algorithm.

  16. Preferences UnderUncertainty and the Deficiencies of the Expected Utility Model

    OpenAIRE

    Murat Tasdemir

    2007-01-01

    In economics, the prevailing framework to explain preferences under uncerta- inty is the Expected Utility theory. Despite its widespread use, the Expected Utility theory is not free from problems. Experimental and empirical works shows that, in real life, the choices of individuals among risky alternatives conflict with the axioms of the Expected Utility theory. This study, in the light of experimental studies, investigates the problems with the Expected Utility theory regarding the individua...

  17. A single-item inventory model for expected inventory order crossovers

    NARCIS (Netherlands)

    Riezebos, J.; Gaalman, G.J.C.

    2009-01-01

    Expected inventory order crossovers Occur if at the moment of ordering it is expected that orders will not arrive in the sequence they are ordered. Recent research has shown that (it) expected inventory order crossovers will be encountered more frequently in future, and that (b) use of a myopic

  18. Context, Experience, Expectation, and Action—Towards an Empirically Grounded, General Model for Analyzing Biographical Uncertainty

    Directory of Open Access Journals (Sweden)

    Herwig Reiter

    2010-01-01

    Full Text Available The article proposes a general, empirically grounded model for analyzing biographical uncertainty. The model is based on findings from a qualitative-explorative study of transforming meanings of unemployment among young people in post-Soviet Lithuania. In a first step, the particular features of the uncertainty puzzle in post-communist youth transitions are briefly discussed. A historical event like the collapse of state socialism in Europe, similar to the recent financial and economic crisis, is a generator of uncertainty par excellence: it undermines the foundations of societies and the taken-for-grantedness of related expectations. Against this background, the case of a young woman and how she responds to the novel threat of unemployment in the transition to the world of work is introduced. Her uncertainty management in the specific time perspective of certainty production is then conceptually rephrased by distinguishing three types or levels of biographical uncertainty: knowledge, outcome, and recognition uncertainty. Biographical uncertainty, it is argued, is empirically observable through the analysis of acting and projecting at the biographical level. The final part synthesizes the empirical findings and the conceptual discussion into a stratification model of biographical uncertainty as a general tool for the biographical analysis of uncertainty phenomena. URN: urn:nbn:de:0114-fqs100120

  19. Artificial Intelligence versus Statistical Modeling and Optimization of Cholesterol Oxidase Production by using Streptomyces Sp.

    Science.gov (United States)

    Pathak, Lakshmi; Singh, Vineeta; Niwas, Ram; Osama, Khwaja; Khan, Saif; Haque, Shafiul; Tripathi, C K M; Mishra, B N

    2015-01-01

    Cholesterol oxidase (COD) is a bi-functional FAD-containing oxidoreductase which catalyzes the oxidation of cholesterol into 4-cholesten-3-one. The wider biological functions and clinical applications of COD have urged the screening, isolation and characterization of newer microbes from diverse habitats as a source of COD and optimization and over-production of COD for various uses. The practicability of statistical/ artificial intelligence techniques, such as response surface methodology (RSM), artificial neural network (ANN) and genetic algorithm (GA) have been tested to optimize the medium composition for the production of COD from novel strain Streptomyces sp. NCIM 5500. All experiments were performed according to the five factor central composite design (CCD) and the generated data was analysed using RSM and ANN. GA was employed to optimize the models generated by RSM and ANN. Based upon the predicted COD concentration, the model developed with ANN was found to be superior to the model developed with RSM. The RSM-GA approach predicted maximum of 6.283 U/mL COD production, whereas the ANN-GA approach predicted a maximum of 9.93 U/mL COD concentration. The optimum concentrations of the medium variables predicted through ANN-GA approach were: 1.431 g/50 mL soybean, 1.389 g/50 mL maltose, 0.029 g/50 mL MgSO4, 0.45 g/50 mL NaCl and 2.235 ml/50 mL glycerol. The experimental COD concentration was concurrent with the GA predicted yield and led to 9.75 U/mL COD production, which was nearly two times higher than the yield (4.2 U/mL) obtained with the un-optimized medium. This is the very first time we are reporting the statistical versus artificial intelligence based modeling and optimization of COD production by Streptomyces sp. NCIM 5500.

  20. Using Models to Teach about Climate Change: A look at NGSS Expectations and Teacher Perceptions

    Science.gov (United States)

    Yarker, M. B.; Stanier, C. O.; Forbes, C.; Park, S.

    2013-12-01

    The Next Generation Science Standards have been updated from the previous version of the standards with some much needed emphasis on topics in climate and climate change. In particular, the standards have focused on K-12 students learning about science models, which is extremely important when discussing climate change. The NGSS suggest that students be able to 1) develop and use science models (not just use them to explain a concept) because this is how scientists actually use models during the scientific process; and 2) understand systems and system models across all science concepts and all age levels because it leads to further understanding about a more complex natural system (like climate change). To summarize, the NGSS expects that K-12 students should develop and use system models across disciplines and age groups in a way that is similar to how scientists use them in practice, which is to make predictions about unanswered questions. Research indicates that students who learn about science content using an approach that aligns more authentically with the way real science inquiry is done have a better understanding of the content, better understanding of the nature of science, improved critical thinking skills, and improved problem solving skills. Research also indicates that most teachers are aware of this method to teach science content, but sometimes have trouble implementing it into the classroom effectively for many reasons. If accepted, this presentation will share an approach to incorporate modeling into the classroom effectively as well as report the results from a study that qualitatively look at three teacher's perspectives on using models in the classroom while teaching units about climate change, in order to identify how/why teachers struggle to teach about models involved in content related to climate change. Preliminary results indicate that the teachers in this study view models as an effective way to explain a concept to their students, but

  1. Expectation values of local fields for a two-parameter family of integrable models and related perturbed conformal field theories

    International Nuclear Information System (INIS)

    Baseilhac, P.; Fateev, V.A.

    1998-01-01

    We calculate the vacuum expectation values of local fields for the two-parameter family of integrable field theories introduced and studied by Fateev (1996). Using this result we propose an explicit expression for the vacuum expectation values of local operators in parafermionic sine-Gordon models and in integrable perturbed SU(2) coset conformal field theories. (orig.)

  2. Modeling predicted that tobacco control policies targeted at lower educated will reduce the differences in life expectancy

    NARCIS (Netherlands)

    Bemelmans, W.J.E.; Lenthe, F. van; Hoogenveen, R.; Kunst, A.; Deeg, D.J.H.; Brandt, P.A. van den; Goldbohm, R.A.; Verschuren, W.M.M.

    2006-01-01

    Background and Objective: To estimate the effects of reducing the prevalence of smoking in lower educated groups on educational differences in life expectancy. Methods: A dynamic Markov-type multistate transition model estimated the effects on life expectancy of two scenarios. A "maximum scenario"

  3. Health Status and Health Dynamics in an Empirical Model of Expected Longevity*

    Science.gov (United States)

    Benítez-Silva, Hugo; Ni, Huan

    2010-01-01

    Expected longevity is an important factor influencing older individuals’ decisions such as consumption, savings, purchase of life insurance and annuities, claiming of Social Security benefits, and labor supply. It has also been shown to be a good predictor of actual longevity, which in turn is highly correlated with health status. A relatively new literature on health investments under uncertainty, which builds upon the seminal work by Grossman (1972), has directly linked longevity with characteristics, behaviors, and decisions by utility maximizing agents. Our empirical model can be understood within that theoretical framework as estimating a production function of longevity. Using longitudinal data from the Health and Retirement Study, we directly incorporate health dynamics in explaining the variation in expected longevities, and compare two alternative measures of health dynamics: the self-reported health change, and the computed health change based on self-reports of health status. In 38% of the reports in our sample, computed health changes are inconsistent with the direct report on health changes over time. And another 15% of the sample can suffer from information losses if computed changes are used to assess changes in actual health. These potentially serious problems raise doubts regarding the use and interpretation of the computed health changes and even the lagged measures of self-reported health as controls for health dynamics in a variety of empirical settings. Our empirical results, controlling for both subjective and objective measures of health status and unobserved heterogeneity in reporting, suggest that self-reported health changes are a preferred measure of health dynamics. PMID:18187217

  4. Distraction sneakers decrease the expected level of aggression within groups: a game-theoretic model.

    Science.gov (United States)

    Dubois, Frédérique; Giraldeau, Luc-Alain; Hamilton, Ian M; Grant, James W A; Lefebvre, Louis

    2004-08-01

    Hawk-dove games have been extensively used to predict the conditions under which group-living animals should defend their resources against potential usurpers. Typically, game-theoretic models on aggression consider that resource defense may entail energetic and injury costs. However, intruders may also take advantage of owners who are busy fighting to sneak access to unguarded resources, imposing thereby an additional cost on the use of the escalated hawk strategy. In this article we modify the two-strategy hawk-dove game into a three-strategy hawk-dove-sneaker game that incorporates a distraction-sneaking tactic, allowing us to explore its consequences on the expected level of aggression within groups. Our model predicts a lower proportion of hawks and hence lower frequencies of aggressive interactions within groups than do previous two-strategy hawk-dove games. The extent to which distraction sneakers decrease the frequency of aggression within groups, however, depends on whether they search only for opportunities to join resources uncovered by other group members or for both unchallenged resources and opportunities to usurp.

  5. Problems for superstring models with vacuum expectation values for conjugate sneutrinos

    International Nuclear Information System (INIS)

    Campbell, B.; Ellis, J.; Gaillard, M.K.; Nanopoulos, D.V.; Olive, K.A.

    1986-01-01

    Superstring models compactified on Calabi-Yau manifolds contain two new neutral scalars in each 27 generation of chiral supermultiplets. We consider implications of a vacuum expectation value for one of the neutral scalars, the conjugates neutrino ν tilde L c : L c vertical stroke0>=y. Apart from a coupling which generates a Dirac neutrino mass and which must be small [ -9 )], its only superpotential interaction is with D L d L , so there wold be D-d mixing if y≠0. The fact that m d is not much less than m e or m u then tells us that y ν , arises if y≠0, and the D-d mixing would then induce the decay K→π+a ν at an unacceptable rate. Regardless of the gauge group rank, we show that the combined constraints on D-d mixing, and on the flavour-changing neutral currents it would induce, are sufficient to rule out D L d L c ν L c superpotential coupling large enough to produce L c vertical stroke0>≠0. These problems are avoided in models with a rank-5 gauge group and L c vertical stroke0>< or approx.40 KeV. (orig.)

  6. Comparison of different artificial neural network architectures in modeling of Chlorella sp. flocculation.

    Science.gov (United States)

    Zenooz, Alireza Moosavi; Ashtiani, Farzin Zokaee; Ranjbar, Reza; Nikbakht, Fatemeh; Bolouri, Oberon

    2017-07-03

    Biodiesel production from microalgae feedstock should be performed after growth and harvesting of the cells, and the most feasible method for harvesting and dewatering of microalgae is flocculation. Flocculation modeling can be used for evaluation and prediction of its performance under different affective parameters. However, the modeling of flocculation in microalgae is not simple and has not performed yet, under all experimental conditions, mostly due to different behaviors of microalgae cells during the process under different flocculation conditions. In the current study, the modeling of microalgae flocculation is studied with different neural network architectures. Microalgae species, Chlorella sp., was flocculated with ferric chloride under different conditions and then the experimental data modeled using artificial neural network. Neural network architectures of multilayer perceptron (MLP) and radial basis function architectures, failed to predict the targets successfully, though, modeling was effective with ensemble architecture of MLP networks. Comparison between the performances of the ensemble and each individual network explains the ability of the ensemble architecture in microalgae flocculation modeling.

  7. Estimation of Unobserved Inflation Expectations in India using State-Space Model

    OpenAIRE

    Chattopadhyay, Siddhartha; Sahu, Sohini; Jha, Saakshi

    2016-01-01

    Inflation expectations is an important marker for monetary policy makers. India being a new entrant to the group of countries that pursue inflation targeting as its monetary policy objective, estimating the inflation expectation is of paramount importance. This paper estimates the unobserved inflation expectations in India between 1993:Q1 to 2016:Q1 from the Fisher equation relation using the state space approach (Kalman Filter). We find that our results match well with the inflation forecast...

  8. Computational-Model-Based Analysis of Context Effects on Harmonic Expectancy

    OpenAIRE

    Morimoto, Satoshi; Remijn, Gerard B.; Nakajima, Yoshitaka

    2016-01-01

    Expectancy for an upcoming musical chord, harmonic expectancy, is supposedly based on automatic activation of tonal knowledge. Since previous studies implicitly relied on interpretations based on Western music theory, the underlying computational processes involved in harmonic expectancy and how it relates to tonality need further clarification. In particular, short chord sequences which cannot lead to unique keys are difficult to interpret in music theory. In this study, we examined effects ...

  9. Expectation values of local fields in the Bullough-Dodd model and integrable perturbed conformal field theories

    International Nuclear Information System (INIS)

    Fateev, V.; Lukyanov, S.; Zamolodchikov, A.; Zamolodchikov, A.

    1998-01-01

    Exact expectation values of the fields e aφ in the Bullough-Dodd model are derived by adopting the ''''reflection relations'''' which involve the reflection S-matrix of the Liouville theory, as well as a special analyticity assumption. Using this result we propose explicit expressions for expectation values of all primary operators in the c 1,2 or Φ 2,1 . Some results concerning the Φ 1,5 perturbed minimal models are also presented. (orig.)

  10. The Things You Do: Internal Models of Others' Expected Behaviour Guide Action Observation.

    Directory of Open Access Journals (Sweden)

    Kimberley C Schenke

    Full Text Available Predictions allow humans to manage uncertainties within social interactions. Here, we investigate how explicit and implicit person models-how different people behave in different situations-shape these predictions. In a novel action identification task, participants judged whether actors interacted with or withdrew from objects. In two experiments, we manipulated, unbeknownst to participants, the two actors action likelihoods across situations, such that one actor typically interacted with one object and withdrew from the other, while the other actor showed the opposite behaviour. In Experiment 2, participants additionally received explicit information about the two individuals that either matched or mismatched their actual behaviours. The data revealed direct but dissociable effects of both kinds of person information on action identification. Implicit action likelihoods affected response times, speeding up the identification of typical relative to atypical actions, irrespective of the explicit knowledge about the individual's behaviour. Explicit person knowledge, in contrast, affected error rates, causing participants to respond according to expectations instead of observed behaviour, even when they were aware that the explicit information might not be valid. Together, the data show that internal models of others' behaviour are routinely re-activated during action observation. They provide first evidence of a person-specific social anticipation system, which predicts forthcoming actions from both explicit information and an individuals' prior behaviour in a situation. These data link action observation to recent models of predictive coding in the non-social domain where similar dissociations between implicit effects on stimulus identification and explicit behavioural wagers have been reported.

  11. [Offered income, salary expectations, and the economic activity of married women: an analytic model].

    Science.gov (United States)

    Lollivier, S

    1984-06-01

    This study uses data from tax declarations for 40,000 French households for 1975 to propose a model that permits quantification of the effects of certain significant factors on the economic activity of married women. The PROBIT model of analysis of variance was used to determine the specific effect of several variables, including age of the woman, number of children under 25 years of age in the household, the age of the youngest child, husband's income and socioprofessional status, wife's level and type of education, size of community of residence and region of residence. The principal factors influencing activity rates were found to be educational level, age, and to those of childless women, but activity rates dropped by about 30% for mothers of 2 and even more for mothers of 3 or more children. Influence of the place of residence and the husband's income were associated with lesser disparities. The reasons for variations in female labor force participation can be viewed as analogous to a balance. Underlying factors can increase or decrease the income the woman hopes to earn (offered income) as well as the minimum income for which she will work (required salary). A TOBIT model was constructed in which income was a function of age, education, geographic location, and number of children, and salary required was a function of the variables related to the husband including income and socioprofessional status. For most of the effects considered, the observed variation in activity rates resulted from variations in offered income. The husband's income influences only the desired salary. The offered income decreases and the required salary increases when the number of children is 2 or more, reducing the rate of activity. More educated women have slightly greater salary expectations, but command much higher salaries, resulting in an increased rate of professional activity.

  12. From Teacher to Manager: Expectations and Challenge in the Further Education Sector. A Relationship Model

    Science.gov (United States)

    Corbett, Stephen

    2017-01-01

    In a turbulent working environment with varying expectations and challenges is it fair to expect further education teachers and managers to maintain and improve standards? This article highlights that with the incorporation of colleges began a series of initiatives to professionalise the FE sector. This coupled with pressures for those who work…

  13. Competing risk model for reduction in life expectancy from radiogenic latent cancer

    International Nuclear Information System (INIS)

    Davis, H.T.

    1978-01-01

    Because of the large number of persons who could potentially receive low doses of radiation as a result of a nuclear reactor accident, the number of fatalities from latent cancers is generally larger than the early, or prompt, fatalities. For this reason the latent cancer fatality risk of reactor accidents is perceived as being more important than the early fatality risk. In addition, there exists the temptation to add the latent cancer fatality risk to the early fatality risk for the purpose of comparing reactor accident risks to other risks that society is exposed to, such as automobile accidents, airplane accidents, hurricanes, etc. However, the impact on the individual, and society as a whole, due to latent cancer fatalities is significantly different from the impact produced by early fatalities. Early fatalities generally result in appreciable life shortening for the affected individual while latent cancer fatalities generally result in very limited life shortening. A mathematical model was developed to express the reduction in life expectancy due to latent radiogenic cancer as a function of dose received

  14. Modeling the expected performance of the REgolith X-ray Imaging Spectrometer (REXIS)

    Science.gov (United States)

    Inamdar, Niraj K.; Binzel, Richard P.; Hong, Jae Sub; Allen, Branden; Grindlay, Jonathan; Masterson, Rebecca A.

    2014-09-01

    OSIRIS-REx is the third spacecraft in the NASA New Frontiers Program and is planned for launch in 2016. OSIRIS-REx will orbit the near-Earth asteroid (101955) Bennu, characterize it, and return a sample of the asteroid's regolith back to Earth. The Regolith X-ray Imaging Spectrometer (REXIS) is an instrument on OSIRIS-REx designed and built by students at MIT and Harvard. The purpose of REXIS is to collect and image sun-induced fluorescent X-rays emitted by Bennu, thereby providing spectroscopic information related to the elemental makeup of the asteroid regolith and the distribution of features over its surface. Telescopic reflectance spectra suggest a CI or CM chondrite analog meteorite class for Bennu, where this primitive nature strongly motivates its study. A number of factors, however, will influence the generation, measurement, and interpretation of the X-ray spectra measured by REXIS. These include: the compositional nature and heterogeneity of Bennu, the time-variable solar state, X-ray detector characteristics, and geometric parameters for the observations. In this paper, we will explore how these variables influence the precision to which REXIS can measure Bennu's surface composition. By modeling the aforementioned factors, we place bounds on the expected performance of REXIS and its ability to ultimately place Bennu in an analog meteorite class.

  15. Culture-related service expectations: a comparative study using the Kano model.

    Science.gov (United States)

    Hejaili, Fayez F; Assad, Lina; Shaheen, Faissal A; Moussa, Dujana H; Karkar, Ayman; AlRukhaimi, Mona; Barhamein, Majdah; Al Suwida, Abdulkareem; Al Alhejaili, Faris F; Al Harbi, Ali S; Al Homrany, Mohamed; Attar, Bisher; Al-Sayyari, Abdulla A

    2009-01-01

    To compare service expectations between Arab and Austrian patients. We used a Kano model-based questionnaire with 20 service attributes of relevance to the dialysis patient. We analyzed 530, 172, 60, and 68 responses from Saudi, Austrian, Syrian, and UAE patients, respectively. We compared the customer satisfaction coefficient and the frequencies of response categories ("must be," "attractive," "one-dimensional," and "indifferent") for each of the 20 service attributes and in each of the 3 national groups of patients. We also investigated whether any differences seen were related to sex, age, literacy rate, or duration on dialysis. We observed higher satisfaction coefficients and "one-directional" responses among Arab patients and higher dissatisfaction coefficients and "must be" and "attractive" responses among Austrian patients. These were not related to age or duration on dialysis but were related to literacy rate. We speculate that these discrepancies between Austrian and Arab patients might be related to underdeveloped sophistication in market competitive forces and to cultural influences.

  16. Internal models of target motion: expected dynamics overrides measured kinematics in timing manual interceptions.

    Science.gov (United States)

    Zago, Myrka; Bosco, Gianfranco; Maffei, Vincenzo; Iosa, Marco; Ivanenko, Yuri P; Lacquaniti, Francesco

    2004-04-01

    Prevailing views on how we time the interception of a moving object assume that the visual inputs are informationally sufficient to estimate the time-to-contact from the object's kinematics. Here we present evidence in favor of a different view: the brain makes the best estimate about target motion based on measured kinematics and an a priori guess about the causes of motion. According to this theory, a predictive model is used to extrapolate time-to-contact from expected dynamics (kinetics). We projected a virtual target moving vertically downward on a wide screen with different randomized laws of motion. In the first series of experiments, subjects were asked to intercept this target by punching a real ball that fell hidden behind the screen and arrived in synchrony with the visual target. Subjects systematically timed their motor responses consistent with the assumption of gravity effects on an object's mass, even when the visual target did not accelerate. With training, the gravity model was not switched off but adapted to nonaccelerating targets by shifting the time of motor activation. In the second series of experiments, there was no real ball falling behind the screen. Instead the subjects were required to intercept the visual target by clicking a mousebutton. In this case, subjects timed their responses consistent with the assumption of uniform motion in the absence of forces, even when the target actually accelerated. Overall, the results are in accord with the theory that motor responses evoked by visual kinematics are modulated by a prior of the target dynamics. The prior appears surprisingly resistant to modifications based on performance errors.

  17. Interacting sp-boson model with isospin: an unified description of giant multipole resonances and other collective motions

    International Nuclear Information System (INIS)

    Chen, C.H.-T.

    1980-10-01

    A unified description of the following classes of nuclear collective states in terms of an interacting sp-boson model is proposed: (i) Low-lying collective states in the light nuclei, both odd-odd and even-even; (ii) Giant multipole resonances (GMR), and (iii) pairing collective motions. (Author) [pt

  18. Cognitive-Behavioral Therapy for Suicide Prevention (CBT-SP): Treatment Model, Feasibility, and Acceptability

    Science.gov (United States)

    Stanley, Barbara; Brown, Gregory; Brent, David A.; Wells, Karen; Poling, Kim; Curry, John; Kennard, Betsy D.; Wagner, Ann; Cwik, Mary F.; Klomek, Anat Brunstein; Goldstein, Tina; Vitiello, Benedetto; Barnett, Shannon; Daniel, Stephanie; Hughes, Jennifer

    2009-01-01

    Objective: To describe the elements of a manual-based cognitive-behavioral therapy for suicide prevention (CBT-SP) and to report its feasibility in preventing the recurrence of suicidal behavior in adolescents who have recently attempted suicide. Method: The CBT-SP was developed using a risk reduction and relapse prevention approach and…

  19. Artificial Intelligence versus Statistical Modeling and Optimization of Cholesterol Oxidase Production by using Streptomyces Sp.

    Directory of Open Access Journals (Sweden)

    Lakshmi Pathak

    Full Text Available Cholesterol oxidase (COD is a bi-functional FAD-containing oxidoreductase which catalyzes the oxidation of cholesterol into 4-cholesten-3-one. The wider biological functions and clinical applications of COD have urged the screening, isolation and characterization of newer microbes from diverse habitats as a source of COD and optimization and over-production of COD for various uses. The practicability of statistical/ artificial intelligence techniques, such as response surface methodology (RSM, artificial neural network (ANN and genetic algorithm (GA have been tested to optimize the medium composition for the production of COD from novel strain Streptomyces sp. NCIM 5500. All experiments were performed according to the five factor central composite design (CCD and the generated data was analysed using RSM and ANN. GA was employed to optimize the models generated by RSM and ANN. Based upon the predicted COD concentration, the model developed with ANN was found to be superior to the model developed with RSM. The RSM-GA approach predicted maximum of 6.283 U/mL COD production, whereas the ANN-GA approach predicted a maximum of 9.93 U/mL COD concentration. The optimum concentrations of the medium variables predicted through ANN-GA approach were: 1.431 g/50 mL soybean, 1.389 g/50 mL maltose, 0.029 g/50 mL MgSO4, 0.45 g/50 mL NaCl and 2.235 ml/50 mL glycerol. The experimental COD concentration was concurrent with the GA predicted yield and led to 9.75 U/mL COD production, which was nearly two times higher than the yield (4.2 U/mL obtained with the un-optimized medium. This is the very first time we are reporting the statistical versus artificial intelligence based modeling and optimization of COD production by Streptomyces sp. NCIM 5500.

  20. Aspirations and Expectations of West Malaysian Youth: Two Models of Social Class Values

    Science.gov (United States)

    Takei, Yoshimitsu; And Others

    1973-01-01

    While the occupational aspirations of Malay and Chinese male students in the secondary schools reveal fairly similar configurations, the socio-economic expectations of Malays are higher and largely independent of social class origins. (Authors)

  1. Expectation values of descendent fields in the Bullough-Dodd model and related perturbed conformal field theories

    International Nuclear Information System (INIS)

    Baseilhac, P.; Stanishkov, M.

    2001-01-01

    The exact vacuum expectation values of the second level descendent fields 2 (∂-barφ 2 e aφ in the Bullough-Dodd model are calculated. By performing quantum group restrictions, we obtain -2 L-bar -2 PHI lk > in the PHI 12 , PHI 21 and PHI 15 perturbed minimal CFTs. In particular, the exact expectation value is found to be proportional to the square of the bulk free energy

  2. Understanding Female Sport Attrition in a Stereotypical Male Sport within the Framework of Eccles's Expectancy-Value Model

    Science.gov (United States)

    Guillet, Emma; Sarrazin, Philippe; Fontayne, Paul; Brustad, Robert J.

    2006-01-01

    An empirical research study based upon the expectancy-value model of Eccles and colleagues (1983) investigated the effect of gender-role orientations on psychological dimensions of female athletes' sport participation and the likelihood of their continued participation in a stereotypical masculine activity. The model (Eccles et al., 1983) posits…

  3. Using the Expectancy Value Model of Motivation to Understand the Relationship between Student Attitudes and Achievement in Statistics

    Science.gov (United States)

    Hood, Michelle; Creed, Peter A.; Neumann, David L.

    2012-01-01

    We tested a model of the relationship between attitudes toward statistics and achievement based on Eccles' Expectancy Value Model (1983). Participants (n = 149; 83% female) were second-year Australian university students in a psychology statistics course (mean age = 23.36 years, SD = 7.94 years). We obtained demographic details, past performance,…

  4. Development and Symbiosis Establishment in the Cnidarian Endosymbiosis Model Aiptasia sp.

    Science.gov (United States)

    Bucher, Madeline; Wolfowicz, Iliona; Voss, Philipp A; Hambleton, Elizabeth A; Guse, Annika

    2016-01-25

    Symbiosis between photosynthetic algae and heterotrophic organisms is widespread. One prominent example of high ecological relevance is the endosymbiosis between dinoflagellate algae of the genus Symbiodinium and reef-building corals, which typically acquire symbionts anew each generation during larval stages. The tropical sea anemone Aiptasia sp. is a laboratory model system for this endosymbiosis and, similar to corals, produces non-symbiotic larvae that establish symbiosis by phagocytosing Symbiodinium from the environment into the endoderm. Here we generate the first overview of Aiptasia embryogenesis and larval development and establish in situ hybridization to analyze expression patterns of key early developmental regulators. Next, we quantify morphological changes in developing larvae and find a substantial enlargement of the gastric cavity over time. Symbiont acquisition starts soon after mouth formation and symbionts occupy a major portion of the host cell in which they reside. During the first 14 days of development, infection efficiency remains constant while in contrast, localization of phagocytosed symbionts changes, indicating that the occurrence of functional phagocytosing cells may be developmentally regulated. Taken together, here we provide the essential framework to further develop Aiptasia as a model system for the analysis of symbiosis establishment in cnidarian larvae at the molecular level.

  5. On the Expected Discounted Penalty Function for the Classical Risk Model with Potentially Delayed Claims and Random Incomes

    Directory of Open Access Journals (Sweden)

    Huiming Zhu

    2014-01-01

    Full Text Available We focus on the expected discounted penalty function of a compound Poisson risk model with random incomes and potentially delayed claims. It is assumed that each main claim will produce a byclaim with a certain probability and the occurrence of the byclaim may be delayed depending on associated main claim amount. In addition, the premium number process is assumed as a Poisson process. We derive the integral equation satisfied by the expected discounted penalty function. Given that the premium size is exponentially distributed, the explicit expression for the Laplace transform of the expected discounted penalty function is derived. Finally, for the exponential claim sizes, we present the explicit formula for the expected discounted penalty function.

  6. Modelling changes in small area disability free life expectancy: trends in London wards between 2001 and 2011.

    Science.gov (United States)

    Congdon, Peter

    2014-12-20

    Existing analyses of trends in disability free life expectancy (DFLE) are mainly at aggregate level (national or broad regional). However, major differences in DFLE, and trends in these expectancies, exist between different neighbourhoods within regions, so supporting a small area perspective. However, this raises issues regarding the stability of conventional life table estimation methods at small area scales. This paper advocates a Bayesian borrowing strength technique to model trends in mortality and disability differences across 625 small areas in London, using illness data from the 2001 and 2011 population Censuses, and deaths data for two periods centred on the Census years. From this analysis, estimates of total life expectancy and DFLE are obtained. The spatio-temporal modelling perspective allows assessment of whether significant compression or expansion of morbidity has occurred in each small area. Appropriate models involve random effects that recognise correlation and interaction effects over relevant dimensions of the observed deaths and illness data (areas, ages), as well as major spatial trends (e.g. gradients in health and mortality according to area deprivation category). Whilst borrowing strength is a primary consideration (and demonstrated by raised precision for estimated life expectancies), so also is model parsimony. Therefore, pure borrowing strength models are compared with models allowing selection of random age-area interaction effects using a spike-slab prior, and in fact borrowing strength combined with random effects selection provides better fit. Copyright © 2014 John Wiley & Sons, Ltd.

  7. Understanding Middle School Students' Motivation in Math Class: The Expectancy-Value Model Perspective

    Science.gov (United States)

    Yurt, Eyup

    2015-01-01

    One of the most important variables affecting middle school students' mathematics performance is motivation. Motivation is closely related with expectancy belief regarding the task and value attached to the task. Identification of which one or ones of the factors constituting motivation is more closely related to mathematics performance may help…

  8. Test models for estimating radiation balance in different scales for Jaboticabal, SP

    Directory of Open Access Journals (Sweden)

    Valquíria de Alencar Beserra

    2012-12-01

    Full Text Available The net radiation (Rn in agroecosystems is the amount of energy that is available in the environment to heating processes of living organisms, air and soil; perspiration of animals and plants; photosynthesis and water evaporation. The Rn defines the type of climate and weather conditions prevailing in a region affecting the availability and thermal water, the fundamental understanding of genotype-environment, which ultimately determine the productivity of the agricultural system. Rn usually is used in models of weather and climate studies. The sustainability and economic viability of zootechnical activity is dependent on the positive interaction between animal and environment. Environmental factors such as water, shading, thermal exchanges sensible heat (conduction, convection and radiation skin and latent heat losses (evaporation and transpiration, conditioned by Rn, must be managed to provide the best results. The present study was conducted to develop and test models for accurate and precise radiation balance on the scales daily, monthly and seasonal ten-day for Jaboticabal - SP, due to the importance of estimates of net radiation for agricultural activities. We used daily meteorological data from weather station located in Jaboticabal, SP (coordinates: 21 ° 14'05 "South, 48 ° 17'09" West, 615m altitude at Universidade Estadual Paulista "Júlio Mesquita Filho" - FCAV/UNESP in a situation of default grass "Bahiagrass" during the period 20/08/2005 to 20/01/2012. The data used were the maximum temperature (Tmax, minimum (Tmin and mean (TMED; maximum relative humidity (URMáx, minimum (URMín and average (URMéd precipitation (mm, average velocity (m/s, Qo, solar radiation (MJ m-2, sunshine (hour meter (MJ m², soil temperature at two depths (Tsoil2CM, Tsoil5CM and class A pan evaporation (TCA (mm. The measures taken by the balance radiometer were taken as a reference to test other models. The models tested were those reported by NORMAN et al

  9. Assessment of the expected construction company’s net profit using neural network and multiple regression models

    Directory of Open Access Journals (Sweden)

    H.H. Mohamad

    2013-09-01

    This research aims to develop a mathematical model for assessing the expected net profit of any construction company. To achieve the research objective, four steps were performed. First, the main factors affecting firms’ net profit were identified. Second, pertinent data regarding the net profit factors were collected. Third, two different net profit models were developed using the Multiple Regression (MR and the Neural Network (NN techniques. The validity of the proposed models was also investigated. Finally, the results of both MR and NN models were compared to investigate the predictive capabilities of the two models.

  10. Charting the Eccles' Expectancy-Value Model from Mothers' Beliefs in Childhood to Youths' Activities in Adolescence

    Science.gov (United States)

    Simpkins, Sandra D.; Fredricks, Jennifer A.; Eccles, Jacquelynne S.

    2012-01-01

    The Eccles' expectancy-value model posits that a cascade of mechanisms explain associations between parents' beliefs and youths' achievement-related behaviors. Specifically, parents' beliefs predict parents' behaviors; in turn, parents' behaviors predict youths' motivational beliefs, and youths' motivational beliefs predict their behaviors. This…

  11. Model averaging in the presence of structural uncertainty about treatment effects: influence on treatment decision and expected value of information.

    Science.gov (United States)

    Price, Malcolm J; Welton, Nicky J; Briggs, Andrew H; Ades, A E

    2011-01-01

    Standard approaches to estimation of Markov models with data from randomized controlled trials tend either to make a judgment about which transition(s) treatments act on, or they assume that treatment has a separate effect on every transition. An alternative is to fit a series of models that assume that treatment acts on specific transitions. Investigators can then choose among alternative models using goodness-of-fit statistics. However, structural uncertainty about any chosen parameterization will remain and this may have implications for the resulting decision and the need for further research. We describe a Bayesian approach to model estimation, and model selection. Structural uncertainty about which parameterization to use is accounted for using model averaging and we developed a formula for calculating the expected value of perfect information (EVPI) in averaged models. Marginal posterior distributions are generated for each of the cost-effectiveness parameters using Markov Chain Monte Carlo simulation in WinBUGS, or Monte-Carlo simulation in Excel (Microsoft Corp., Redmond, WA). We illustrate the approach with an example of treatments for asthma using aggregate-level data from a connected network of four treatments compared in three pair-wise randomized controlled trials. The standard errors of incremental net benefit using structured models is reduced by up to eight- or ninefold compared to the unstructured models, and the expected loss attaching to decision uncertainty by factors of several hundreds. Model averaging had considerable influence on the EVPI. Alternative structural assumptions can alter the treatment decision and have an overwhelming effect on model uncertainty and expected value of information. Structural uncertainty can be accounted for by model averaging, and the EVPI can be calculated for averaged models. Copyright © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights

  12. P-T phase diagram of a holographic s+p model from Gauss-Bonnet gravity

    International Nuclear Information System (INIS)

    Nie, Zhang-Yu; Zeng, Hui

    2015-01-01

    In this paper, we study the holographic s+p model in 5-dimensional bulk gravity with the Gauss-Bonnet term. We work in the probe limit and give the Δ-T phase diagrams at three different values of the Gauss-Bonnet coefficient to show the effect of the Gauss-Bonnet term. We also construct the P-T phase diagrams for the holographic system using two different definitions of the pressure and compare the results.

  13. Expectations and implementations of the flipped classroom model in undergraduate mathematics courses

    Science.gov (United States)

    Naccarato, Emilie; Karakok, Gulden

    2015-10-01

    The flipped classroom model is being used more frequently in undergraduate mathematics courses. As with any new teaching model, in-depth investigations of both various implementation styles and how the new model improves student learning are needed. Currently, many practitioners have been sharing their implementations of this model. However, there has not yet been an investigation of the various implementations of the model to discern general trends in this movement. With this research goal in mind, we conducted a study exploring various implementations of the flipped classroom model by interviewing 19 faculty members who experienced using this model at 14 different institutes. Results indicate that participants had similar motivations for implementation; however, subsequent implementations were different. In addition, we share participants' perspectives on (a) student learning of pre-requisite, procedural and conceptual knowledge, and (b) how this particular model promotes such knowledge developments. Finally, we provide suggestions for future implementations and research regarding this particular teaching model.

  14. Socio-demographic Model of Gender Gap in Expected and Actual Wages in Estonia

    OpenAIRE

    Vassil, Kristjan; Eamets, Raul; Mõtsmees, Pille

    2014-01-01

    Estonia ranks consistently on top of the list of countries with the largest gender pay gap. However, irrespective of abundant aggregate level evidence, little is known what motivates the gap at the individual level. In this paper we precisely address the issue of gender pay gap at the individual level. We examine how large is the gender pay gap in actual and expected wages and how it can be explained. We use a rich dataset from Estonian Labour Force Survey on actual wages, and the data from C...

  15. A CVAR scenario for a standard monetary model using theory-consistent expectations

    DEFF Research Database (Denmark)

    Juselius, Katarina

    2017-01-01

    A theory-consistent CVAR scenario describes a set of testable regularities capturing basic assumptions of the theoretical model. Using this concept, the paper considers a standard model for exchange rate determination and shows that all assumptions about the model's shock structure and steady...

  16. Modelos da distribuição temporal de chuvas intensas em Piracicaba, SP Time distribution models of intense rainfall in Piracicaba, SP, Brazil

    Directory of Open Access Journals (Sweden)

    Décio E. Cruciani

    2002-04-01

    Full Text Available O estudo da variação temporal de chuvas intensas é de grande importância na hidrologia, para a análise e previsão de eventos extremos, necessárias em projetos de controle de engenharia. Com esse objetivo, foram analisados dados de pluviogramas da cidade de Piracicaba, SP, do período de 1966 a 2000, para se determinar a distribuição temporal de chuvas intensas de 60 e de 120 min de duração. As chuvas de 60 min foram subdivididas em três intervalos iguais e sucessivos de 20 min cada um, enquanto as chuvas de 120 min foram subdivididas em quatro intervalos iguais e sucessivos de 30 min cada um. O modelo de distribuição da precipitação que predominou para as chuvas de 60 e 120 min, foi do tipo exponencial negativo, com 85,7 e 50,7% dos casos, respectivamente. Para as chuvas de 60 min, com altura pluviométrica média de 20,7 mm, a distribuição foi de 72,3, 21,4 e 6,2% do total precipitado, respectivamente, nos três intervalos sucessivos de 20 min. Para as chuvas de 120 min, com altura pluviométrica média de 33,3 mm, o resultado foi de 60,1, 25,2, 11,1 e 3,6%, respectivamente, nos quatro intervalos sucessivos de 30 min. O modelo de distribuição temporal dessas chuvas não foi modificado pelo total precipitado nem pela sua duração, nos intervalos em questão.Time distribution models of intense and short rains are very important in hydrology and for extreme predictions in engineering projects. With this purpose, rain data of Piracicaba, SP, Brazil, from 1966 to 2000 were analyzed to establish time distribution models of 60 and 120 min intense rains, during the rainy season from October through March. Time distribution models were assessed by three intervals of twenty minutes duration, for 60 min rains and by four intervals of thirty minutes duration for 120 min rains. The prevailing precipitation model for both, 60 and 120 min rains was a negative exponential distribution, in 85.7 and 50.7% of cases, respectively. For 60 min

  17. Comparison between the Health Belief Model and Subjective Expected Utility Theory: predicting incontinence prevention behaviour in post-partum women.

    Science.gov (United States)

    Dolman, M; Chase, J

    1996-08-01

    A small-scale study was undertaken to test the relative predictive power of the Health Belief Model and Subjective Expected Utility Theory for the uptake of a behaviour (pelvic floor exercises) to reduce post-partum urinary incontinence in primigravida females. A structured questionnaire was used to gather data relevant to both models from a sample antenatal and postnatal primigravida women. Questions examined the perceived probability of becoming incontinent, the perceived (dis)utility of incontinence, the perceived probability of pelvic floor exercises preventing future urinary incontinence, the costs and benefits of performing pelvic floor exercises and sources of information and knowledge about incontinence. Multiple regression analysis focused on whether or not respondents intended to perform pelvic floor exercises and the factors influencing their decisions. Aggregated data were analysed to compare the Health Belief Model and Subjective Expected Utility Theory directly.

  18. Variations on an Expectancy-Value Model of Motivation in Science.

    Science.gov (United States)

    DeBacker; Nelson

    1999-04-01

    Relationships among motivational variables from goal theory and expectancy-value theory were investigated in this correlational study of high school students. Self-report surveys of motivation in science were collected during biology classes from 69 males and 80 females. Outcome measures were effort, persistence, and achievement. Gender differences were noted in the pattern of zero-order correlations. Internal motivation variables were related to achievement in males but not females. Regression analyses indicated that the motivation variables explained large proportions of variance in the outcomes. However, the contribution of individual variables differed by gender. Most notable was perceived ability, which contributed significantly to predicting outcome measures for females but not males. Findings suggest that interventions may need to focus on different motivational aspects depending on gender. Copyright 1999 Academic Press.

  19. Evolutionary Expectations

    DEFF Research Database (Denmark)

    Nash, Ulrik William

    2014-01-01

    , they are correlated among people who share environments because these individuals satisfice within their cognitive bounds by using cues in order of validity, as opposed to using cues arbitrarily. Any difference in expectations thereby arise from differences in cognitive ability, because two individuals with identical...... cognitive bounds will perceive business opportunities identically. In addition, because cues provide information about latent causal structures of the environment, changes in causality must be accompanied by changes in cognitive representations if adaptation is to be maintained. The concept of evolutionary......The concept of evolutionary expectations descends from cue learning psychology, synthesizing ideas on rational expectations with ideas on bounded rationality, to provide support for these ideas simultaneously. Evolutionary expectations are rational, but within cognitive bounds. Moreover...

  20. Unequal Expectations

    DEFF Research Database (Denmark)

    Karlson, Kristian Bernt

    the role of causal inference in social science; and it discusses the potential of the findings of the dissertation to inform educational policy. In Chapters II and III, constituting the substantive contribution of the dissertation, I examine the process through which students form expectations...... of the relation between the self and educational prospects; evaluations that are socially bounded in that students take their family's social position into consideration when forming their educational expectations. One important consequence of this learning process is that equally talented students tend to make...... for their educational futures. Focusing on the causes rather than the consequences of educational expectations, I argue that students shape their expectations in response to the signals about their academic performance they receive from institutionalized performance indicators in schools. Chapter II considers...

  1. The role of expectations in the FRB/US macroeconomic model

    OpenAIRE

    Flint Brayton; Eileen Mauskopf; David L. Reifschneider; Peter A. Tinsley; John Williams

    1997-01-01

    In the past year, the staff of the Board of Governors of the Federal Reserve System began using a new macroeconomic model of the U.S. economy referred to as the FRB/US model. This system of mathematical equations, describing interactions among economic measures such as inflation, interest rates, and gross domestic product, is one of the tools used in economic forecasting and the analysis of macroeconomic policy issues at the Board. The FRB/US model replaces the MPS model, which, with periodic...

  2. Modeling Quality-Adjusted Life Expectancy Loss Resulting from Tobacco Use in the United States

    Science.gov (United States)

    Kaplan, Robert M.; Anderson, John P.; Kaplan, Cameron M.

    2007-01-01

    Purpose: To describe the development of a model for estimating the effects of tobacco use upon Quality Adjusted Life Years (QALYs) and to estimate the impact of tobacco use on health outcomes for the United States (US) population using the model. Method: We obtained estimates of tobacco consumption from 6 years of the National Health Interview…

  3. Expected Utility and Entropy-Based Decision-Making Model for Large Consumers in the Smart Grid

    Directory of Open Access Journals (Sweden)

    Bingtuan Gao

    2015-09-01

    Full Text Available In the smart grid, large consumers can procure electricity energy from various power sources to meet their load demands. To maximize its profit, each large consumer needs to decide their energy procurement strategy under risks such as price fluctuations from the spot market and power quality issues. In this paper, an electric energy procurement decision-making model is studied for large consumers who can obtain their electric energy from the spot market, generation companies under bilateral contracts, the options market and self-production facilities in the smart grid. Considering the effect of unqualified electric energy, the profit model of large consumers is formulated. In order to measure the risks from the price fluctuations and power quality, the expected utility and entropy is employed. Consequently, the expected utility and entropy decision-making model is presented, which helps large consumers to minimize their expected profit of electricity procurement while properly limiting the volatility of this cost. Finally, a case study verifies the feasibility and effectiveness of the proposed model.

  4. Walls of massive K\\"ahler sigma models on SO(2N)/U(N) and Sp(N)/U(N)

    OpenAIRE

    Arai, Masato; Shin, Sunyoung

    2011-01-01

    We study the Bogomol'nyi-Prasad-Sommerfield wall solutions in massive K\\"ahler nonlinear sigma models on SO(2N)/U(N) and Sp(N)/U(N) in three-dimensional spacetime. We show that SO(2N)/U(N) and Sp(N)/U(N) models have 2^{N-1} and 2^N discrete vacua, respectively. We explicitly construct the exact BPS multiwall solutions for N\\le 3.

  5. Gender and work-family conflict: testing the rational model and the gender role expectations model in the Spanish cultural context.

    Science.gov (United States)

    Calvo-Salguero, Antonia; Martínez-de-Lecea, José-María Salinas; del Carmen Aguilar-Luzón, María

    2012-01-01

    Gutek, Searle, and Klepa (1991) proposed two models to explain the gender differences in work-family conflict: the rational model and the gender role expectations model. Both models have mostly been tested on American and Canadian samples, and have obtained partial support. Given the cultural differences between North American countries and Spain, we should question whether the two models are equally applicable to Spanish society or whether one of them captures Spanish men and women's experience of work-family conflict better than the other. So, the aim of this study is to test which of the models better explains the gender differences in work-family conflict in the Spanish cultural context (or if, indeed, the two models apply equally well). Given the typical cultural dimensions of Spanish society, we expected to find greater support for the gender role expectations model than for the rational model. However, the results obtained in this study indicated that, while the rational model can explain the gender differences that were found, the gender role expectations model cannot capture Spanish people's work-family conflict experiences. The results are interpreted in terms of cultural dimensions characteristic of the Spanish context.

  6. Possibility/Necessity-Based Probabilistic Expectation Models for Linear Programming Problems with Discrete Fuzzy Random Variables

    Directory of Open Access Journals (Sweden)

    Hideki Katagiri

    2017-10-01

    Full Text Available This paper considers linear programming problems (LPPs where the objective functions involve discrete fuzzy random variables (fuzzy set-valued discrete random variables. New decision making models, which are useful in fuzzy stochastic environments, are proposed based on both possibility theory and probability theory. In multi-objective cases, Pareto optimal solutions of the proposed models are newly defined. Computational algorithms for obtaining the Pareto optimal solutions of the proposed models are provided. It is shown that problems involving discrete fuzzy random variables can be transformed into deterministic nonlinear mathematical programming problems which can be solved through a conventional mathematical programming solver under practically reasonable assumptions. A numerical example of agriculture production problems is given to demonstrate the applicability of the proposed models to real-world problems in fuzzy stochastic environments.

  7. Cloud ice: A climate model challenge with signs and expectations of progress

    Science.gov (United States)

    Waliser, Duane E.; Li, Jui-Lin F.; Woods, Christopher P.; Austin, Richard T.; Bacmeister, Julio; Chern, Jiundar; Del Genio, Anthony; Jiang, Jonathan H.; Kuang, Zhiming; Meng, Huan; Minnis, Patrick; Platnick, Steve; Rossow, William B.; Stephens, Graeme L.; Sun-Mack, Szedung; Tao, Wei-Kuo; Tompkins, Adrian M.; Vane, Deborah G.; Walker, Christopher; Wu, Dong

    2009-04-01

    Present-day shortcomings in the representation of upper tropospheric ice clouds in general circulation models (GCMs) lead to errors in weather and climate forecasts as well as account for a source of uncertainty in climate change projections. An ongoing challenge in rectifying these shortcomings has been the availability of adequate, high-quality, global observations targeting ice clouds and related precipitating hydrometeors. In addition, the inadequacy of the modeled physics and the often disjointed nature between model representation and the characteristics of the retrieved/observed values have hampered GCM development and validation efforts from making effective use of the measurements that have been available. Thus, even though parameterizations in GCMs accounting for cloud ice processes have, in some cases, become more sophisticated in recent years, this development has largely occurred independently of the global-scale measurements. With the relatively recent addition of satellite-derived products from Aura/Microwave Limb Sounder (MLS) and CloudSat, there are now considerably more resources with new and unique capabilities to evaluate GCMs. In this article, we illustrate the shortcomings evident in model representations of cloud ice through a comparison of the simulations assessed in the Intergovernmental Panel on Climate Change Fourth Assessment Report, briefly discuss the range of global observational resources that are available, and describe the essential components of the model parameterizations that characterize their "cloud" ice and related fields. Using this information as background, we (1) discuss some of the main considerations and cautions that must be taken into account in making model-data comparisons related to cloud ice, (2) illustrate present progress and uncertainties in applying satellite cloud ice (namely from MLS and CloudSat) to model diagnosis, (3) show some indications of model improvements, and finally (4) discuss a number of

  8. Perturbation theory in angular quantization approach and the expectation values of exponential fields in sine-Gordon model

    International Nuclear Information System (INIS)

    Poghossian, R.H.

    2000-01-01

    In an angular quantization approach a perturbation theory for the Massive Thirring Model (MTM) is developed, which allows us to calculate vacuum expectation values of exponential fields in sine-Gordon theory near the free fermion point in first order of the MTM coupling constant g. The Hankel transforms play an important role when carrying out these calculations. The expression we have found coincides with that of the direct expansion over g of the exact formula conjectured by Lukyanov and Zamolodchikov

  9. Expect With Me: development and evaluation design for an innovative model of group prenatal care to improve perinatal outcomes.

    Science.gov (United States)

    Cunningham, Shayna D; Lewis, Jessica B; Thomas, Jordan L; Grilo, Stephanie A; Ickovics, Jeannette R

    2017-05-18

    Despite biomedical advances and intervention efforts, rates of preterm birth and other adverse outcomes in the United States have remained relatively intransigent. Evidence suggests that group prenatal care can reduce these risks, with implications for maternal and child health as well as substantial cost savings. However, widespread dissemination presents challenges, in part because training and health systems have not been designed to deliver care in a group setting. This manuscript describes the design and evaluation of Expect With Me, an innovative model of group prenatal care with a strong integrated information technology (IT) platform designed to be scalable nationally. Expect With Me follows clinical guidelines from the American Congress of Obstetricians and Gynecologists. Expect With Me incorporates the best evidence-based features of existing models of group care with a novel integrated IT platform designed to improve patient engagement and support, enhance health behaviors and decision making, connect providers and patients, and improve health service delivery. A multisite prospective longitudinal cohort study is being conducted to examine the impact of Expect With Me on perinatal and postpartum outcomes, and to identify and address barriers to national scalability. Process and outcome evaluation will include quantitative and qualitative data collection at patient, provider, and organizational levels. Mixed-method data collection includes patient surveys, medical record reviews, patient focus groups; provider surveys, session evaluations, provider focus groups and in-depth interviews; an online tracking system; and clinical site visits. A two-to-one matched cohort of women receiving individual care from each site will provide a comparison group (n = 1,000 Expect With Me patients; n = 2,000 individual care patients) for outcome and cost analyses. By bundling prevention and care services into a high-touch, high-tech group prenatal care model

  10. Modeling Noisy Data with Differential Equations Using Observed and Expected Matrices

    Science.gov (United States)

    Deboeck, Pascal R.; Boker, Steven M.

    2010-01-01

    Complex intraindividual variability observed in psychology may be well described using differential equations. It is difficult, however, to apply differential equation models in psychological contexts, as time series are frequently short, poorly sampled, and have large proportions of measurement and dynamic error. Furthermore, current methods for…

  11. Bayesian parameter estimation in the Expectancy Valence model of the Iowa gamblling task

    NARCIS (Netherlands)

    Wetzels, R.; Vandekerckhove, J.; Tuerlinckx, F.; Wagenmakers, E.-J.

    2010-01-01

    The purpose of the popular Iowa gambling task is to study decision making deficits in clinical populations by mimicking real-life decision making in an experimental context. Busemeyer and Stout [Busemeyer, J. R., & Stout, J. C. (2002). A contribution of cognitive decision models to clinical

  12. Expected shortfall estimation for apparently infinite-mean models of operational risk

    NARCIS (Netherlands)

    Cirillo, P.; Taleb, Nassim Nicholas

    2016-01-01

    Statistical analyses on actual data depict operational risk as an extremely heavy-tailed phenomenon, able to generate losses so extreme as to suggest the use of infinite-mean models. But no loss can actually destroy more than the entire value of a bank or of a company, and this upper bound should be

  13. SP-100 Program overview

    International Nuclear Information System (INIS)

    Truscello, V.C.

    1984-01-01

    The SP-100 Program is expected to go through three phases: technology assessment and advancement, ground testing, and flight qualification. Currently the program is in the two- to three-year technology assessment and advancement stage. Goals are to identify the space nuclear power system concept that best meets anticipated requirements of future space missions, assess the technical feasibility of that concept, and establish a cost and schedule for developing the concept. The SP-100 Project Office has begun the implementation activities needed to meet these goals. With regard to refractory alloys, a better data base will be required before we move ahead in the program from technology assessment to ground demonstration

  14. Evaluation of the product ratio coherent model in forecasting mortality rates and life expectancy at births by States

    Science.gov (United States)

    Shair, Syazreen Niza; Yusof, Aida Yuzi; Asmuni, Nurin Haniah

    2017-05-01

    Coherent mortality forecasting models have recently received increasing attention particularly in their application to sub-populations. The advantage of coherent models over independent models is the ability to forecast a non-divergent mortality for two or more sub-populations. One of the coherent models was recently developed by [1] known as the product-ratio model. This model is an extension version of the functional independent model from [2]. The product-ratio model has been applied in a developed country, Australia [1] and has been extended in a developing nation, Malaysia [3]. While [3] accounted for coherency of mortality rates between gender and ethnic group, the coherency between states in Malaysia has never been explored. This paper will forecast the mortality rates of Malaysian sub-populations according to states using the product ratio coherent model and its independent version— the functional independent model. The forecast accuracies of two different models are evaluated using the out-of-sample error measurements— the mean absolute forecast error (MAFE) for age-specific death rates and the mean forecast error (MFE) for the life expectancy at birth. We employ Malaysian mortality time series data from 1991 to 2014, segregated by age, gender and states.

  15. Great Expectations

    NARCIS (Netherlands)

    Dickens, Charles

    2005-01-01

    One of Dickens's most renowned and enjoyable novels, Great Expectations tells the story of Pip, an orphan boy who wishes to transcend his humble origins and finds himself unexpectedly given the opportunity to live a life of wealth and respectability. Over the course of the tale, in which Pip

  16. 2018 Military Retirement Options: An Expected Net Present Value Decision Analysis Model

    Science.gov (United States)

    2017-03-23

    and the Operational Research Commons This Thesis is brought to you for free and open access by AFIT Scholar. It has been accepted for inclusion in...and build a representation of the model using Microsoft Excel 2016, Visual Basics for Applications ( VBA ), and Excel’s Data Analysis Toolkit. The...stream of future income. However, these DOD TSP contributions are not readily accessible to the member until they reach age 59.5 due to IRS

  17. Expected for acquisition movement exercise is more effective for functional recovery than simple exercise in a rat model of hemiplegia.

    Science.gov (United States)

    Ikeda, Satoshi; Ohwatashi, Akihiko; Harada, Katsuhiro; Kamikawa, Yurie; Yoshida, Akira

    2013-01-01

    The use of novel rehabilitative approaches for effecting functional recovery following stroke is controversial. Effects of different but effective rehabilitative interventions in the hemiplegic patient are not clear. We studied the effects of different rehabilitative approaches on functional recovery in the rat photochecmical cerebral infarction model. Twenty-four male Wistar rats aged 8 weeks were used. The cranial bone was exposed under deep anesthesia. Rose bengal (20 mg/kg) was injected intravenously, and the sensorimotor area of the cerebral cortex was irradiated transcranially for 20 min with a light beam of 533-nm wavelength. Animals were divided into 3 groups. In the simple-exercise group, treadmill exercise was performed for 20 min every day. In the expected for acquisition movement-training group, beam-walking exercise was done for 20 min daily. The control group was left to recover without additional intervention. Hindlimb function was evaluated with the beam-walking test. Following cerebral infarction, dysfunction of the contralateral extremities was observed. Functional recovery was observed earlier in the expected for acquisition training group than in the other groups. Although rats in the treadmill group recovered more quickly than controls, the beam-walking group had the shortest overall recovery time. Exercise facilitated functional recovery in the rat hemiplegic model, and expected for acquisition exercise was more effective than simple exercise. These findings are considered to have important implications for the future development of clinical rehabilitation programs.

  18. The Financial Coaching Advice Model: An Exploration into how it Satisfies Expectations of Quality Advice

    Directory of Open Access Journals (Sweden)

    Julie Knutsen

    2012-11-01

    Full Text Available For 20 years, the financial planning sector in Australia has been transitioning from a sales-orientated force to aprofession of qualified and skilled practitioners. Today, the potential for professional financial planning adviceto benefit Australians financially, economically and psychologically is recognised by government. Financially,these benefits include increased savings, less interest expense through faster debt reduction, higher investmentreturns and appropriate levels of insurance. Economically, a more financially literate society has the potentialfor less reliance on an already burdened social security system. Psychologically, the benefits include the peaceof mind that comes from an individual being confident in financial matters. However, despite this level ofrecognition and development, national surveys have reported that only a small percentage of the populationactually seek professional financial advice. The factors attributing to these low percentages included the gapsin financial literacy limiting an individual’s engagement in financial matters and consumer’s current mistrust ofthe financial advice business models that remain dominated by commission-driven product sales. Thesedeficiencies have led some financial planning firms to break from financial product sales as the primary advicemodel and focus on financial coaching. Exploratory interviews with the practitioners and clients of a selectedfinancial planning firm have generated insightful discussion into how a financial coaching advice model isachieving the financial, economic and psychological benefits recognised by government as the potentialoutcomes of professional financial advice. The aim of this paper is to present the findings from that discussionand demonstrate the opportunities embedded within a financial coaching advice model. It is argued that thisdiscussion offers a foundation for future research direction in an area currently under researched in

  19. What to expect from dynamical modelling of galactic haloes - II. The spherical Jeans equation

    Science.gov (United States)

    Wang, Wenting; Han, Jiaxin; Cole, Shaun; More, Surhud; Frenk, Carlos; Schaller, Matthieu

    2018-06-01

    The spherical Jeans equation (SJE) is widely used in dynamical modelling of the Milky Way (MW) halo potential. We use haloes and galaxies from the cosmological Millennium-II simulation and hydrodynamical APOSTLE (A Project of Simulations of The Local Environment) simulations to investigate the performance of the SJE in recovering the underlying mass profiles of MW mass haloes. The best-fitting halo mass and concentration parameters scatter by 25 per cent and 40 per cent around their input values, respectively, when dark matter particles are used as tracers. This scatter becomes as large as a factor of 3 when using star particles instead. This is significantly larger than the estimated statistical uncertainty associated with the use of the SJE. The existence of correlated phase-space structures that violate the steady-state assumption of the SJE as well as non-spherical geometries is the principal source of the scatter. Binary haloes show larger scatter because they are more aspherical in shape and have a more perturbed dynamical state. Our results confirm that the number of independent phase-space structures sets an intrinsic limiting precision on dynamical inferences based on the steady-state assumption. Modelling with a radius-independent velocity anisotropy, or using tracers within a limited outer radius, result in significantly larger scatter, but the ensemble-averaged measurement over the whole halo sample is approximately unbiased.

  20. Learned helplessness or expectancy-value? A psychological model for describing the experiences of different categories of unemployed people.

    Science.gov (United States)

    García Rodríguez, Y

    1997-06-01

    Various studies have explored the relationships between unemployment and expectation of success, commitment to work, motivation, causal attributions, self-esteem and depression. A model is proposed that assumes the relationships between these variables are moderated by (a) whether or not the unemployed individual is seeking a first job and (b) age. It is proposed that for the unemployed who are seeking their first job (seekers) the relationships among these variables will be consistent with expectancy-value theory, but for those who have had a previous job (losers), the relationships will be more consistent with learned helplessness theory. It is further assumed that within this latter group the young losers will experience "universal helplessness" whereas the adult losers will experience "personal helplessness".

  1. Experiments expectations

    OpenAIRE

    Gorini, B; Meschi, E

    2014-01-01

    This paper presents the expectations and the constraints of the experiments relatively to the commissioning procedure and the running conditions for the 2015 data taking period. The views about the various beam parameters for the p-p period, like beam energy, maximum pileup, bunch spacing and luminosity limitation in IP2 and IP8, are discussed. The goals and the constraints of the 2015 physics program are also presented, including the heavy ions period as well as the special...

  2. Essential and non-essential DNA replication genes in the model halophilic Archaeon, Halobacterium sp. NRC-1

    Directory of Open Access Journals (Sweden)

    DasSarma Shiladitya

    2007-06-01

    Full Text Available Abstract Background Information transfer systems in Archaea, including many components of the DNA replication machinery, are similar to those found in eukaryotes. Functional assignments of archaeal DNA replication genes have been primarily based upon sequence homology and biochemical studies of replisome components, but few genetic studies have been conducted thus far. We have developed a tractable genetic system for knockout analysis of genes in the model halophilic archaeon, Halobacterium sp. NRC-1, and used it to determine which DNA replication genes are essential. Results Using a directed in-frame gene knockout method in Halobacterium sp. NRC-1, we examined nineteen genes predicted to be involved in DNA replication. Preliminary bioinformatic analysis of the large haloarchaeal Orc/Cdc6 family, related to eukaryotic Orc1 and Cdc6, showed five distinct clades of Orc/Cdc6 proteins conserved in all sequenced haloarchaea. Of ten orc/cdc6 genes in Halobacterium sp. NRC-1, only two were found to be essential, orc10, on the large chromosome, and orc2, on the minichromosome, pNRC200. Of the three replicative-type DNA polymerase genes, two were essential: the chromosomally encoded B family, polB1, and the chromosomally encoded euryarchaeal-specific D family, polD1/D2 (formerly called polA1/polA2 in the Halobacterium sp. NRC-1 genome sequence. The pNRC200-encoded B family polymerase, polB2, was non-essential. Accessory genes for DNA replication initiation and elongation factors, including the putative replicative helicase, mcm, the eukaryotic-type DNA primase, pri1/pri2, the DNA polymerase sliding clamp, pcn, and the flap endonuclease, rad2, were all essential. Targeted genes were classified as non-essential if knockouts were obtained and essential based on statistical analysis and/or by demonstrating the inability to isolate chromosomal knockouts except in the presence of a complementing plasmid copy of the gene. Conclusion The results showed that ten

  3. Little Evidence Exists To Support The Expectation That Providers Would Consolidate To Enter New Payment Models.

    Science.gov (United States)

    Neprash, Hannah T; Chernew, Michael E; McWilliams, J Michael

    2017-02-01

    Provider consolidation has been associated with higher health care prices and spending. The prevailing wisdom is that payment reform will accelerate consolidation, especially between physicians and hospitals and among physician groups, as providers position themselves to bear financial risk for the full continuum of patient care. Drawing on data from a number of sources from 2008 onward, we examined the relationship between Medicare's accountable care organization (ACO) programs and provider consolidation. We found that consolidation was under way in the period 2008-10, before the Affordable Care Act (ACA) established the ACO programs. While the number of hospital mergers and the size of specialty-oriented physician groups increased after the ACA was passed, we found minimal evidence that consolidation was associated with ACO penetration at the market level or with physicians' participation in ACOs within markets. We conclude that payment reform has been associated with little acceleration in consolidation in addition to trends already under way, but there is evidence of potential defensive consolidation in response to new payment models. Project HOPE—The People-to-People Health Foundation, Inc.

  4. Do French macroseismic intensity observations agree with expectations from the European Seismic Hazard Model 2013?

    Science.gov (United States)

    Rey, Julien; Beauval, Céline; Douglas, John

    2018-02-01

    Probabilistic seismic hazard assessments are the basis of modern seismic design codes. To test fully a seismic hazard curve at the return periods of interest for engineering would require many thousands of years' worth of ground-motion recordings. Because strong-motion networks are often only a few decades old (e.g. in mainland France the first accelerometric network dates from the mid-1990s), data from such sensors can be used to test hazard estimates only at very short return periods. In this article, several hundreds of years of macroseismic intensity observations for mainland France are interpolated using a robust kriging-with-a-trend technique to establish the earthquake history of every French mainland municipality. At 24 selected cities representative of the French seismic context, the number of exceedances of intensities IV, V and VI is determined over time windows considered complete. After converting these intensities to peak ground accelerations using the global conversion equation of Caprio et al. (Ground motion to intensity conversion equations (GMICEs): a global relationship and evaluation of regional dependency, Bulletin of the Seismological Society of America 105:1476-1490, 2015), these exceedances are compared with those predicted by the European Seismic Hazard Model 2013 (ESHM13). In half of the cities, the number of observed exceedances for low intensities (IV and V) is within the range of predictions of ESHM13. In the other half of the cities, the number of observed exceedances is higher than the predictions of ESHM13. For intensity VI, the match is closer, but the comparison is less meaningful due to a scarcity of data. According to this study, the ESHM13 underestimates hazard in roughly half of France, even when taking into account the uncertainty in the conversion from intensity to acceleration. However, these results are valid only for the acceleration range tested in this study (0.01 to 0.09 g).

  5. Do French macroseismic intensity observations agree with expectations from the European Seismic Hazard Model 2013?

    Science.gov (United States)

    Rey, Julien; Beauval, Céline; Douglas, John

    2018-05-01

    Probabilistic seismic hazard assessments are the basis of modern seismic design codes. To test fully a seismic hazard curve at the return periods of interest for engineering would require many thousands of years' worth of ground-motion recordings. Because strong-motion networks are often only a few decades old (e.g. in mainland France the first accelerometric network dates from the mid-1990s), data from such sensors can be used to test hazard estimates only at very short return periods. In this article, several hundreds of years of macroseismic intensity observations for mainland France are interpolated using a robust kriging-with-a-trend technique to establish the earthquake history of every French mainland municipality. At 24 selected cities representative of the French seismic context, the number of exceedances of intensities IV, V and VI is determined over time windows considered complete. After converting these intensities to peak ground accelerations using the global conversion equation of Caprio et al. (Ground motion to intensity conversion equations (GMICEs): a global relationship and evaluation of regional dependency, Bulletin of the Seismological Society of America 105:1476-1490, 2015), these exceedances are compared with those predicted by the European Seismic Hazard Model 2013 (ESHM13). In half of the cities, the number of observed exceedances for low intensities (IV and V) is within the range of predictions of ESHM13. In the other half of the cities, the number of observed exceedances is higher than the predictions of ESHM13. For intensity VI, the match is closer, but the comparison is less meaningful due to a scarcity of data. According to this study, the ESHM13 underestimates hazard in roughly half of France, even when taking into account the uncertainty in the conversion from intensity to acceleration. However, these results are valid only for the acceleration range tested in this study (0.01 to 0.09 g).

  6. Cell-bound lipases from Burkholderia sp. ZYB002: gene sequence analysis, expression, enzymatic characterization, and 3D structural model.

    Science.gov (United States)

    Shu, Zhengyu; Lin, Hong; Shi, Shaolei; Mu, Xiangduo; Liu, Yanru; Huang, Jianzhong

    2016-05-03

    The whole-cell lipase from Burkholderia cepacia has been used as a biocatalyst in organic synthesis. However, there is no report in the literature on the component or the gene sequence of the cell-bound lipase from this species. Qualitative analysis of the cell-bound lipase would help to illuminate the regulation mechanism of gene expression and further improve the yield of the cell-bound lipase by gene engineering. Three predictive cell-bound lipases, lipA, lipC21 and lipC24, from Burkholderia sp. ZYB002 were cloned and expressed in E. coli. Both LipA and LipC24 displayed the lipase activity. LipC24 was a novel mesophilic enzyme and displayed preference for medium-chain-length acyl groups (C10-C14). The 3D structural model of LipC24 revealed the open Y-type active site. LipA displayed 96 % amino acid sequence identity with the known extracellular lipase. lipA-inactivation and lipC24-inactivation decreased the total cell-bound lipase activity of Burkholderia sp. ZYB002 by 42 % and 14 %, respectively. The cell-bound lipase activity from Burkholderia sp. ZYB002 originated from a multi-enzyme mixture with LipA as the main component. LipC24 was a novel lipase and displayed different enzymatic characteristics and structural model with LipA. Besides LipA and LipC24, other type of the cell-bound lipases (or esterases) should exist.

  7. A combined model of sensory and cognitive representations underlying tonal expectations in music: from audio signals to behavior.

    Science.gov (United States)

    Collins, Tom; Tillmann, Barbara; Barrett, Frederick S; Delbé, Charles; Janata, Petr

    2014-01-01

    Listeners' expectations for melodies and harmonies in tonal music are perhaps the most studied aspect of music cognition. Long debated has been whether faster response times (RTs) to more strongly primed events (in a music theoretic sense) are driven by sensory or cognitive mechanisms, such as repetition of sensory information or activation of cognitive schemata that reflect learned tonal knowledge, respectively. We analyzed over 300 stimuli from 7 priming experiments comprising a broad range of musical material, using a model that transforms raw audio signals through a series of plausible physiological and psychological representations spanning a sensory-cognitive continuum. We show that RTs are modeled, in part, by information in periodicity pitch distributions, chroma vectors, and activations of tonal space--a representation on a toroidal surface of the major/minor key relationships in Western tonal music. We show that in tonal space, melodies are grouped by their tonal rather than timbral properties, whereas the reverse is true for the periodicity pitch representation. While tonal space variables explained more of the variation in RTs than did periodicity pitch variables, suggesting a greater contribution of cognitive influences to tonal expectation, a stepwise selection model contained variables from both representations and successfully explained the pattern of RTs across stimulus categories in 4 of the 7 experiments. The addition of closure--a cognitive representation of a specific syntactic relationship--succeeded in explaining results from all 7 experiments. We conclude that multiple representational stages along a sensory-cognitive continuum combine to shape tonal expectations in music. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  8. Best Practice Life Expectancy

    DEFF Research Database (Denmark)

    Medford, Anthony

    2017-01-01

    been reported previously by various authors. Though remarkable, this is simply an empirical observation. Objective: We examine best-practice life expectancy more formally by using extreme value theory. Methods: Extreme value distributions are fit to the time series (1900 to 2012) of maximum life......Background: Whereas the rise in human life expectancy has been extensively studied, the evolution of maximum life expectancies, i.e., the rise in best-practice life expectancy in a group of populations, has not been examined to the same extent. The linear rise in best-practice life expectancy has...... expectancies at birth and age 65, for both sexes, using data from the Human Mortality Database and the United Nations. Conclusions: Generalized extreme value distributions offer a theoretically justified way to model best-practice life expectancies. Using this framework one can straightforwardly obtain...

  9. Forecasting value-at-risk and expected shortfall using fractionally integrated models of conditional volatility: international evidence

    OpenAIRE

    Degiannakis, Stavros; Floros, Christos; Dent, P.

    2013-01-01

    The present study compares the performance of the long memory FIGARCH model, with that of the short memory GARCH specification, in the forecasting of multi-period Value-at-Risk (VaR) and Expected Shortfall (ES) across 20 stock indices worldwide. The dataset is comprised of daily data covering the period from 1989 to 2009. The research addresses the question of whether or not accounting for long memory in the conditional variance specification improves the accuracy of the VaR and ES forecasts ...

  10. Environmental interactions and the SP-100 power system

    International Nuclear Information System (INIS)

    Ferguson, D.C.

    1993-01-01

    The Civil Space Technology Initiative High-Capacity-Power Environmental Interactions Program has made great progress in defining and evaluating the interactions of the SP-100 power system with its expected ambient environments. The NASCAP/LEO and POLAR computer codes demonstrated that local electric fields at the user interface module are high. Therefore, particular attention must be paid to geometries and materials in this region to prevent arcing at conductor-insulator junctions in low Earth orbit. NASCAP/LEO and EPSAT computer models revealed that SP-100 payloads float about 100 V negative of the LEO plasma. In addition, ground tests and modeling done for the Space Station Freedom Electrical Grounding Tiger Team found that dielectric coatings often break down at such voltages in a plasma. Thus, surface coatings for SP-100 payloads should be carefully selected. Sputtering may also be a concern for long-duration missions in LEO at these voltages. Much work has been done on a sputtering model to evaluate surface material loss rates on SP-100 payloads. In ground plasma chamber tests of cables and cable insulators at SP-100 voltages, parasitic power losses due to the plasma current collected from possible pinholes or coating defects were quantified and shown to be small. Modeling revealed that the power loss from currents to other surfaces is also small. The atomic oxygen durability of SP-100 materials and coatings continues to be investigated in ground tests. In the upcoming Evaluation of Oxygen Interaction with Materials (EOIM-3) Shuttle flight experiment, a host of SP-100 materials will be evaluated for atomic oxygen durability in LEO. Finally, an evaluation of the interactions of the SP-100 power system with lunar and planetary environments has started. At a workshop on chemical and electrical interactions on Mars recently held at the NASA Lewis Research Center, many of primary interactions were identified

  11. External Validation Study of First Trimester Obstetric Prediction Models (Expect Study I): Research Protocol and Population Characteristics.

    Science.gov (United States)

    Meertens, Linda Jacqueline Elisabeth; Scheepers, Hubertina Cj; De Vries, Raymond G; Dirksen, Carmen D; Korstjens, Irene; Mulder, Antonius Lm; Nieuwenhuijze, Marianne J; Nijhuis, Jan G; Spaanderman, Marc Ea; Smits, Luc Jm

    2017-10-26

    A number of first-trimester prediction models addressing important obstetric outcomes have been published. However, most models have not been externally validated. External validation is essential before implementing a prediction model in clinical practice. The objective of this paper is to describe the design of a study to externally validate existing first trimester obstetric prediction models, based upon maternal characteristics and standard measurements (eg, blood pressure), for the risk of pre-eclampsia (PE), gestational diabetes mellitus (GDM), spontaneous preterm birth (PTB), small-for-gestational-age (SGA) infants, and large-for-gestational-age (LGA) infants among Dutch pregnant women (Expect Study I). The results of a pilot study on the feasibility and acceptability of the recruitment process and the comprehensibility of the Pregnancy Questionnaire 1 are also reported. A multicenter prospective cohort study was performed in The Netherlands between July 1, 2013 and December 31, 2015. First trimester obstetric prediction models were systematically selected from the literature. Predictor variables were measured by the Web-based Pregnancy Questionnaire 1 and pregnancy outcomes were established using the Postpartum Questionnaire 1 and medical records. Information about maternal health-related quality of life, costs, and satisfaction with Dutch obstetric care was collected from a subsample of women. A pilot study was carried out before the official start of inclusion. External validity of the models will be evaluated by assessing discrimination and calibration. Based on the pilot study, minor improvements were made to the recruitment process and online Pregnancy Questionnaire 1. The validation cohort consists of 2614 women. Data analysis of the external validation study is in progress. This study will offer insight into the generalizability of existing, non-invasive first trimester prediction models for various obstetric outcomes in a Dutch obstetric population

  12. Groundwater age and lifetime expectancy modelling approach for site characterization and performance assessment of radwaste repository in clay formation

    International Nuclear Information System (INIS)

    Cornaton, F.; Perrochet, P.; Benabderrahmane, H.

    2010-01-01

    Document available in extended abstract form only. A deep geological repository of high level and long lived radwaste requires an understanding of the far field and near field groundwater flow and of the transport properties, at actual and future climatic conditions. Andra, French National radioactive waste management Agency, is developing since last 15 years an integrated multi-scale hydrogeological model of whole Paris basin of 200000 km 2 of area (regional scale) to produce a regional flow field associated to groundwater behavior. It includes locally the Meuse/Haute Marne clay site of about 250 km 2 of area in the eastern part of the Paris basin that was chosen for the emplacement of a repository. The Callovo-Oxfordian host formation is a clay layer characterized by a very low permeability of the order 10 -14 m/s, a mean thickness of 130 m at about 500 m depth, and is embedded by calcareous aquifer formations (Dogger and Oxfordian). The hydrogeological conceptual model is based on stratigraphic and petro-physic modeling of the Paris basin and is accounting for the structural, geological, hydrogeological and geochemical data in an integrated way. This model represents 27 hydrogeological units at the scale of the Paris Basin, and it is refined at the scale of the sector to represent 27 different layers that range in age from the Trias to the Portlandian. The finite element flow and transport simulator Ground Water (GW) is used to solve for groundwater flow at steady-state in a 3 Million elements model, considering current climatic conditions. The model is calibrated against about 1250 hydraulic head measurements, and results in maximum absolute hydraulic head differences of 20 meters at the regional scale and 3 meters at the local scale. The calibrated reference model includes transmissive major faults as well as structures acting as barrier to flow. Groundwater age (the time elapsed since recharge) and lifetime expectancy (the time remaining prior to exit) are

  13. Investigating healthy life expectancy using a multi-state model in the presence of missing data and misclassification

    Directory of Open Access Journals (Sweden)

    Ardo van den Hout

    2014-04-01

    Full Text Available Background: A continuous-time three-state model can be used to describe change in cognitive function in the older population. State 1 corresponds to normal cognitive function, state 2 to cognitive impairment, and state 3 to dead. For statistical inference, longitudinal data are available from the UK Medical Research Council Cognitive Function and Ageing Study. Objective: The aim is statistical analysis of longitudinal multi-state data taking into account missing data and potential misclassification of state. In addition, methods for long-term prediction of the transition process are of interest, specifically when applied to the study of healthy life expectancy. Methods: Cognitive function in the older population is assumed to be stable or declining. For this reason, observed improvement of cognitive function is assumed to be caused by misclassification of either state 1 or 2. Regression models for the transition intensities are formulated to incorporate covariate information. Maximum likelihood is used for statistical inference. Results: It is shown that missing values for the state at a pre-scheduled time can easily be taken into account. Long-term prediction is explained and illustrated by the estimation of statespecific life expectancies. In addition, it is shown how microsimulation can be used to further explore predictions based on a fitted multi-state model. Conclusions: Statistical analysis of longitudinal multi-state data can take into account missing data and potential misclassification of state. With respect to long-term prediction, microsimulation is a useful tool for summarising and displaying characteristics of cognitive decline and survival. Comments: ---

  14. Community expectations

    International Nuclear Information System (INIS)

    Kraemer, L.

    2004-01-01

    Historically, the relationship between the nuclear generator and the local community has been one of stability and co-operation. However in more recent times (2000-2003) the nuclear landscape has had several major issues that directly effect the local nuclear host communities. - The associations mandate is to be supportive of the nuclear industry through ongoing dialogue, mutual cooperation and education, - To strengthen community representation with the nuclear industry and politically through networking with other nuclear host communities. As a result of these issues, the Mayors of a number of communities started having informal meetings to discuss the issues at hand and how they effect their constituents. These meetings led to the official formation of the CANHC with representation from: In Canada it is almost impossible to discuss decommissioning and dismantling of Nuclear Facilities without also discussing Nuclear Waste disposal for reasons that I will soon make clear. Also I would like to briefly touch on how and why expectation of communities may differ by geography and circumstance. (author)

  15. Implementing Generalized Additive Models to Estimate the Expected Value of Sample Information in a Microsimulation Model: Results of Three Case Studies.

    Science.gov (United States)

    Rabideau, Dustin J; Pei, Pamela P; Walensky, Rochelle P; Zheng, Amy; Parker, Robert A

    2018-02-01

    The expected value of sample information (EVSI) can help prioritize research but its application is hampered by computational infeasibility, especially for complex models. We investigated an approach by Strong and colleagues to estimate EVSI by applying generalized additive models (GAM) to results generated from a probabilistic sensitivity analysis (PSA). For 3 potential HIV prevention and treatment strategies, we estimated life expectancy and lifetime costs using the Cost-effectiveness of Preventing AIDS Complications (CEPAC) model, a complex patient-level microsimulation model of HIV progression. We fitted a GAM-a flexible regression model that estimates the functional form as part of the model fitting process-to the incremental net monetary benefits obtained from the CEPAC PSA. For each case study, we calculated the expected value of partial perfect information (EVPPI) using both the conventional nested Monte Carlo approach and the GAM approach. EVSI was calculated using the GAM approach. For all 3 case studies, the GAM approach consistently gave similar estimates of EVPPI compared with the conventional approach. The EVSI behaved as expected: it increased and converged to EVPPI for larger sample sizes. For each case study, generating the PSA results for the GAM approach required 3 to 4 days on a shared cluster, after which EVPPI and EVSI across a range of sample sizes were evaluated in minutes. The conventional approach required approximately 5 weeks for the EVPPI calculation alone. Estimating EVSI using the GAM approach with results from a PSA dramatically reduced the time required to conduct a computationally intense project, which would otherwise have been impractical. Using the GAM approach, we can efficiently provide policy makers with EVSI estimates, even for complex patient-level microsimulation models.

  16. Proposal for intake model for workers at IPEN-CNEN/SP who handle {sup 131} I; Proposta de um modelo de incorporacao para trabalhadores ocupacionais do IPEN-CNEN/SP que manuseiam {sup 131} I

    Energy Technology Data Exchange (ETDEWEB)

    Todo, A.S.; Potiens Junior, A.J.; Gaburo, J.C.; Sanches, M.P.; Oliveira, E.M. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)

    1997-12-31

    The intake model for the two groups of workers at IPEN-CNEN/SP is presented. They handle iodine compounds during the processing of irradiated targets and at labeling of radiopharmaceutical compounds. The intake model for the workers are proposed from the knowledge of the activities carried out in the plant and the internal monitoring program of the workers. In this study, the intake is considered to be taken uniformly during the days of major activities carried out by the workers. In practice, the application of this model has be shown suitable, for the studied groups 5 refs., 2 figs., 1 tab.; e-mail: astodo at net.ipen.br

  17. Modeling multiple time series annotations as noisy distortions of the ground truth: An Expectation-Maximization approach.

    Science.gov (United States)

    Gupta, Rahul; Audhkhasi, Kartik; Jacokes, Zach; Rozga, Agata; Narayanan, Shrikanth

    2018-01-01

    Studies of time-continuous human behavioral phenomena often rely on ratings from multiple annotators. Since the ground truth of the target construct is often latent, the standard practice is to use ad-hoc metrics (such as averaging annotator ratings). Despite being easy to compute, such metrics may not provide accurate representations of the underlying construct. In this paper, we present a novel method for modeling multiple time series annotations over a continuous variable that computes the ground truth by modeling annotator specific distortions. We condition the ground truth on a set of features extracted from the data and further assume that the annotators provide their ratings as modification of the ground truth, with each annotator having specific distortion tendencies. We train the model using an Expectation-Maximization based algorithm and evaluate it on a study involving natural interaction between a child and a psychologist, to predict confidence ratings of the children's smiles. We compare and analyze the model against two baselines where: (i) the ground truth in considered to be framewise mean of ratings from various annotators and, (ii) each annotator is assumed to bear a distinct time delay in annotation and their annotations are aligned before computing the framewise mean.

  18. Disability transitions and health expectancies among adults 45 years and older in Malawi: a cohort-based model.

    Directory of Open Access Journals (Sweden)

    Collin F Payne

    Full Text Available Falling fertility and increasing life expectancy contribute to a growing elderly population in sub-Saharan Africa (SSA; by 2060, persons aged 45 y and older are projected to be 25% of SSA's population, up from 10% in 2010. Aging in SSA is associated with unique challenges because of poverty and inadequate social supports. However, despite its importance for understanding the consequences of population aging, the evidence about the prevalence of disabilities and functional limitations due to poor physical health among older adults in SSA continues to be very limited.Participants came from 2006, 2008, and 2010 waves of the Malawi Longitudinal Survey of Families and Health, a study of the rural population in Malawi. We investigate how poor physical health results in functional limitations that limit the day-to-day activities of individuals in domains relevant to this subsistence-agriculture context. These disabilities were parameterized based on questions from the SF-12 questionnaire about limitations in daily living activities. We estimated age-specific patterns of functional limitations and the transitions over time between different disability states using a discrete-time hazard model. The estimated transition rates were then used to calculate the first (to our knowledge microdata-based health expectancies calculated for SSA. The risks of experiencing functional limitations due to poor physical health are high in this population, and the onset of disabilities happens early in life. Our analyses show that 45-y-old women can expect to spend 58% (95% CI, 55%-64% of their remaining 28 y of life (95% CI, 25.7-33.5 with functional limitations; 45-y-old men can expect to live 41% (95% CI, 35%-46% of their remaining 25.4 y (95% CI, 23.3-28.8 with such limitations. Disabilities related to functional limitations are shown to have a substantial negative effect on individuals' labor activities, and are negatively related to subjective well

  19. Disability transitions and health expectancies among adults 45 years and older in Malawi: a cohort-based model.

    Science.gov (United States)

    Payne, Collin F; Mkandawire, James; Kohler, Hans-Peter

    2013-01-01

    Falling fertility and increasing life expectancy contribute to a growing elderly population in sub-Saharan Africa (SSA); by 2060, persons aged 45 y and older are projected to be 25% of SSA's population, up from 10% in 2010. Aging in SSA is associated with unique challenges because of poverty and inadequate social supports. However, despite its importance for understanding the consequences of population aging, the evidence about the prevalence of disabilities and functional limitations due to poor physical health among older adults in SSA continues to be very limited. Participants came from 2006, 2008, and 2010 waves of the Malawi Longitudinal Survey of Families and Health, a study of the rural population in Malawi. We investigate how poor physical health results in functional limitations that limit the day-to-day activities of individuals in domains relevant to this subsistence-agriculture context. These disabilities were parameterized based on questions from the SF-12 questionnaire about limitations in daily living activities. We estimated age-specific patterns of functional limitations and the transitions over time between different disability states using a discrete-time hazard model. The estimated transition rates were then used to calculate the first (to our knowledge) microdata-based health expectancies calculated for SSA. The risks of experiencing functional limitations due to poor physical health are high in this population, and the onset of disabilities happens early in life. Our analyses show that 45-y-old women can expect to spend 58% (95% CI, 55%-64%) of their remaining 28 y of life (95% CI, 25.7-33.5) with functional limitations; 45-y-old men can expect to live 41% (95% CI, 35%-46%) of their remaining 25.4 y (95% CI, 23.3-28.8) with such limitations. Disabilities related to functional limitations are shown to have a substantial negative effect on individuals' labor activities, and are negatively related to subjective well-being. Individuals in this

  20. Expected utility without utility

    OpenAIRE

    Castagnoli, E.; Licalzi, M.

    1996-01-01

    This paper advances an interpretation of Von Neumann–Morgenstern’s expected utility model for preferences over lotteries which does not require the notion of a cardinal utility over prizes and can be phrased entirely in the language of probability. According to it, the expected utility of a lottery can be read as the probability that this lottery outperforms another given independent lottery. The implications of this interpretation for some topics and models in decision theory are considered....

  1. A parallel process model of the development of positive smoking expectancies and smoking behavior during early adolescence in Caucasian and African American girls

    OpenAIRE

    Chung, Tammy; White, Helene R.; Hipwell, Alison E.; Stepp, Stephanie D.; Loeber, Rolf

    2010-01-01

    This study examined the development of positive smoking expectancies and smoking behavior in an urban cohort of girls followed annually over ages 11-14. Longitudinal data from the oldest cohort of the Pittsburgh Girls Study (N=566, 56% African American, 44% Caucasian) were used to estimate a parallel process growth model of positive smoking expectancies and smoking behavior. Average level of positive smoking expectancies was relatively stable over ages 11-14, although there was significant va...

  2. Pharmacokinetic modelling of intravenous tobramycin in adolescent and adult patients with cystic fibrosis using the nonparametric expectation maximization (NPEM) algorithm.

    Science.gov (United States)

    Touw, D J; Vinks, A A; Neef, C

    1997-06-01

    The availability of personal computer programs for individualizing drug dosage regimens has stimulated the interest in modelling population pharmacokinetics. Data from 82 adolescent and adult patients with cystic fibrosis (CF) who were treated with intravenous tobramycin because of an exacerbation of their pulmonary infection were analysed with a non-parametric expectation maximization (NPEM) algorithm. This algorithm estimates the entire discrete joint probability density of the pharmacokinetic parameters. It also provides traditional parametric statistics such as the means, standard deviation, median, covariances and correlations among the various parameters. It also provides graphic-2- and 3-dimensional representations of the marginal densities of the parameters investigated. Several models for intravenous tobramycin in adolescent and adult patients with CF were compared. Covariates were total body weight (for the volume of distribution) and creatinine clearance (for the total body clearance and elimination rate). Because of lack of data on patients with poor renal function, restricted models with non-renal clearance and the non-renal elimination rate constant fixed at literature values of 0.15 L/h and 0.01 h-1 were also included. In this population, intravenous tobramycin could be best described by median (+/-dispersion factor) volume of distribution per unit of total body weight of 0.28 +/- 0.05 L/kg, elimination rate constant of 0.25 +/- 0.10 h-1 and elimination rate constant per unit of creatinine clearance of 0.0008 +/- 0.0009 h-1/(ml/min/1.73 m2). Analysis of populations of increasing size showed that using a restricted model with a non-renal elimination rate constant fixed at 0.01 h-1, a model based on a population of only 10 to 20 patients, contained parameter values similar to those of the entire population and, using the full model, a larger population (at least 40 patients) was needed.

  3. Dielectrophoresis of Tetraselmis sp., a unicellular green alga, in travelling electric fields analyzed using the RC model for a spheroid

    Directory of Open Access Journals (Sweden)

    Sakshin Bunthawin

    2011-10-01

    Full Text Available Dielectrophoresis of a unicellular green alga, Tetraselmis sp., in a travelling electric field was analyzed using an RC(resistor-capacitor-model, instead of the Laplace approach reported in our previous work. The model consists of resistorcapacitorpairs in series to represent the conductive and the capacitive properties of the shell and the inner part of the spheroid.The model is mathematically simpler than the Laplace model and the RC approach is experimentally superior because only thelower critical frequency [LCF] and cell translational speed are required to be measured experimentally. The effective compleximpedance of the spheroid was mathematically modeled to obtain the Clausius-Mossotti factor ([CMF] as a function of celldielectric properties. Spectra of dielectrophoretic velocity and the lower critical frequency of the marine green alga, Tetraselmissp. were investigated to determine cell dielectric properties using a manual curve-fitting method. Effects of arsenic at differentconcentrations on the cell were examined to verify the model. Arsenic severely decreases cytoplasmic conductance (cwhereas it increases membrane conductance (m. Effects were easily observable even at the lowest concentration of arsenicused experimentally (1 ppm. The method offers a practical means of manipulating small plant cells and for rapid screeningfor effects on the dielectric properties of cells of various applied experimental treatments.

  4. Estimation of expected number of accidents and workforce unavailability through Bayesian population variability analysis and Markov-based model

    International Nuclear Information System (INIS)

    Chagas Moura, Márcio das; Azevedo, Rafael Valença; Droguett, Enrique López; Chaves, Leandro Rego; Lins, Isis Didier

    2016-01-01

    Occupational accidents pose several negative consequences to employees, employers, environment and people surrounding the locale where the accident takes place. Some types of accidents correspond to low frequency-high consequence (long sick leaves) events, and then classical statistical approaches are ineffective in these cases because the available dataset is generally sparse and contain censored recordings. In this context, we propose a Bayesian population variability method for the estimation of the distributions of the rates of accident and recovery. Given these distributions, a Markov-based model will be used to estimate the uncertainty over the expected number of accidents and the work time loss. Thus, the use of Bayesian analysis along with the Markov approach aims at investigating future trends regarding occupational accidents in a workplace as well as enabling a better management of the labor force and prevention efforts. One application example is presented in order to validate the proposed approach; this case uses available data gathered from a hydropower company in Brazil. - Highlights: • This paper proposes a Bayesian method to estimate rates of accident and recovery. • The model requires simple data likely to be available in the company database. • These results show the proposed model is not too sensitive to the prior estimates.

  5. Tadpoles, anomaly cancellation and the expectation value of the number of the Higgs particles in the standard model

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2005-01-01

    We motivate the concept of infinitely large and hierarchical matrices in connection with the eight-dimensional super Riemannian tensor and the unification of all fundamental forces. Subsequently, we derive the number of particle-like states and the expectation value of the number of elementary particle content of a minimally extended standard model using the total number of tadpoles and anomaly cancellation condition:nH+29nt-nv=R(8)-N(SM)=2α-bar 0-1=273 where n H is the number of hyper multiplets, n t the number of tensor multiplets, n v the vector multiplets, R (8) is the number of independent components of Riemann's curvature tensor in eight dimensions, N(SM) is the number of elementary particles content of the standard model and α-bar 0 is the inverse fine structure constant. We can conclude that N(SM)=66. Consequently, we conjecture that five Higgs particles should be involved in the standard model

  6. The influence of naphthaleneacetic acid (NAA) and coumarin on flavonoid production by fungus Phellinus sp.: modeling of production kinetic profiles.

    Science.gov (United States)

    Ma, Xiao-Kui; Li, Le; Peterson, Eric Charles; Ruan, Tingting; Duan, Xiaoyi

    2015-11-01

    For the purpose of improving the fungal production of flavonoids, the influence of naphthaleneacetic acid (NAA) and coumarin on flavonoid production by fungus Phellinus sp. P0988 was investigated by developing the corresponding kinetics of flavonoid production in a 7-L bioreactor. Phellinus sp. was confirmed to form flavonoids in pellets and broth when cultivated in basic medium, and the optimum concentration of NAA and coumarin in medium for flavonoid production were determined to be 0.03 and 0.02 g/L, respectively. The developed unstructured mathematical models were in good agreement with the experimental results with respect to flavonoid production kinetic profiles with NAA and coumarin supplementation at optimum levels and revealed significant accuracy in terms of statistical consistency and robustness. Analysis of these kinetic processes indicated that NAA and coumarin supplementations imposed a stronger positive influence on flavonoid production and substrate consumption compared to their effects on cell growth. The separate addition of NAA and coumarin resulted in enhancements in final product accumulation and productivity, achieving final flavonoid concentrations of 3.60 and 2.75 g/L, respectively, and glucose consumption showed a significant decrease compared to the non-supplemented control as well. Also, the separate presence of NAA and coumarin respectively decreased maintenance coefficients (M s) from 2.48 in the control to 1.39 and 0.22, representing decreases of 43.9 and 91.1 %, respectively. The current study is the first known application of mathematical kinetic models to explore the influence of medium components adding on flavonoid production by fungi.

  7. It is time to abandon "expected bladder capacity." Systematic review and new models for children's normal maximum voided volumes.

    Science.gov (United States)

    Martínez-García, Roberto; Ubeda-Sansano, Maria Isabel; Díez-Domingo, Javier; Pérez-Hoyos, Santiago; Gil-Salom, Manuel

    2014-09-01

    There is an agreement to use simple formulae (expected bladder capacity and other age based linear formulae) as bladder capacity benchmark. But real normal child's bladder capacity is unknown. To offer a systematic review of children's normal bladder capacity, to measure children's normal maximum voided volumes (MVVs), to construct models of MVVs and to compare them with the usual formulae. Computerized, manual and grey literature were reviewed until February 2013. Epidemiological, observational, transversal, multicenter study. A consecutive sample of healthy children aged 5-14 years, attending Primary Care centres with no urologic abnormality were selected. Participants filled-in a 3-day frequency-volume chart. Variables were MVVs: maximum of 24 hr, nocturnal, and daytime maximum voided volumes. diuresis and its daytime and nighttime fractions; body-measure data; and gender. The consecutive steps method was used in a multivariate regression model. Twelve articles accomplished systematic review's criteria. Five hundred and fourteen cases were analysed. Three models, one for each of the MVVs, were built. All of them were better adjusted to exponential equations. Diuresis (not age) was the most significant factor. There was poor agreement between MVVs and usual formulae. Nocturnal and daytime maximum voided volumes depend on several factors and are different. Nocturnal and daytime maximum voided volumes should be used with different meanings in clinical setting. Diuresis is the main factor for bladder capacity. This is the first model for benchmarking normal MVVs with diuresis as its main factor. Current formulae are not suitable for clinical use. © 2013 Wiley Periodicals, Inc.

  8. Context effects in a temporal discrimination task" further tests of the Scalar Expectancy Theory and Learning-to-Time models.

    Science.gov (United States)

    Arantes, Joana; Machado, Armando

    2008-07-01

    Pigeons were trained on two temporal bisection tasks, which alternated every two sessions. In the first task, they learned to choose a red key after a 1-s signal and a green key after a 4-s signal; in the second task, they learned to choose a blue key after a 4-s signal and a yellow key after a 16-s signal. Then the pigeons were exposed to a series of test trials in order to contrast two timing models, Learning-to-Time (LeT) and Scalar Expectancy Theory (SET). The models made substantially different predictions particularly for the test trials in which the sample duration ranged from 1 s to 16 s and the choice keys were Green and Blue, the keys associated with the same 4-s samples: LeT predicted that preference for Green should increase with sample duration, a context effect, but SET predicted that preference for Green should not vary with sample duration. The results were consistent with LeT. The present study adds to the literature the finding that the context effect occurs even when the two basic discriminations are never combined in the same session.

  9. The Qualitative Expectations Hypothesis

    DEFF Research Database (Denmark)

    Frydman, Roman; Johansen, Søren; Rahbek, Anders

    2017-01-01

    We introduce the Qualitative Expectations Hypothesis (QEH) as a new approach to modeling macroeconomic and financial outcomes. Building on John Muth's seminal insight underpinning the Rational Expectations Hypothesis (REH), QEH represents the market's forecasts to be consistent with the predictions...... of an economistís model. However, by assuming that outcomes lie within stochastic intervals, QEH, unlike REH, recognizes the ambiguity faced by an economist and market participants alike. Moreover, QEH leaves the model open to ambiguity by not specifying a mechanism determining specific values that outcomes take...

  10. The Qualitative Expectations Hypothesis

    DEFF Research Database (Denmark)

    Frydman, Roman; Johansen, Søren; Rahbek, Anders

    We introduce the Qualitative Expectations Hypothesis (QEH) as a new approach to modeling macroeconomic and financial outcomes. Building on John Muth's seminal insight underpinning the Rational Expectations Hypothesis (REH), QEH represents the market's forecasts to be consistent with the predictions...... of an economist's model. However, by assuming that outcomes lie within stochastic intervals, QEH, unlike REH, recognizes the ambiguity faced by an economist and market participants alike. Moreover, QEH leaves the model open to ambiguity by not specifying a mechanism determining specific values that outcomes take...

  11. Genome Sequence of Pseudomonas sp. Strain Chol1, a Model Organism for the Degradation of Bile Salts and Other Steroid Compounds

    KAUST Repository

    Holert, Johannes; Alam, Intikhab; Larsen, Michael; Antunes, Andre; Bajic, Vladimir B.; Stingl, Ulrich; Philipp, Bodo

    2013-01-01

    Bacterial degradation of steroid compounds is of high ecological and biotechnological relevance. Pseudomonas sp. strain Chol1 is a model organism for studying the degradation of the steroid compound cholate. Its draft genome sequence is presented and reveals one gene cluster responsible for the metabolism of steroid compounds.

  12. Genome Sequence of Pseudomonas sp. Strain Chol1, a Model Organism for the Degradation of Bile Salts and Other Steroid Compounds

    KAUST Repository

    Holert, Johannes

    2013-01-15

    Bacterial degradation of steroid compounds is of high ecological and biotechnological relevance. Pseudomonas sp. strain Chol1 is a model organism for studying the degradation of the steroid compound cholate. Its draft genome sequence is presented and reveals one gene cluster responsible for the metabolism of steroid compounds.

  13. Generation of a statistical shape model with probabilistic point correspondences and the expectation maximization- iterative closest point algorithm

    International Nuclear Information System (INIS)

    Hufnagel, Heike; Pennec, Xavier; Ayache, Nicholas; Ehrhardt, Jan; Handels, Heinz

    2008-01-01

    Identification of point correspondences between shapes is required for statistical analysis of organ shapes differences. Since manual identification of landmarks is not a feasible option in 3D, several methods were developed to automatically find one-to-one correspondences on shape surfaces. For unstructured point sets, however, one-to-one correspondences do not exist but correspondence probabilities can be determined. A method was developed to compute a statistical shape model based on shapes which are represented by unstructured point sets with arbitrary point numbers. A fundamental problem when computing statistical shape models is the determination of correspondences between the points of the shape observations of the training data set. In the absence of landmarks, exact correspondences can only be determined between continuous surfaces, not between unstructured point sets. To overcome this problem, we introduce correspondence probabilities instead of exact correspondences. The correspondence probabilities are found by aligning the observation shapes with the affine expectation maximization-iterative closest points (EM-ICP) registration algorithm. In a second step, the correspondence probabilities are used as input to compute a mean shape (represented once again by an unstructured point set). Both steps are unified in a single optimization criterion which depe nds on the two parameters 'registration transformation' and 'mean shape'. In a last step, a variability model which best represents the variability in the training data set is computed. Experiments on synthetic data sets and in vivo brain structure data sets (MRI) are then designed to evaluate the performance of our algorithm. The new method was applied to brain MRI data sets, and the estimated point correspondences were compared to a statistical shape model built on exact correspondences. Based on established measures of ''generalization ability'' and ''specificity'', the estimates were very satisfactory

  14. Virtual Systems Pharmacology (ViSP software for mechanistic system-level model simulations

    Directory of Open Access Journals (Sweden)

    Sergey eErmakov

    2014-10-01

    Full Text Available Multiple software programs are available for designing and running large scale system-level pharmacology models used in the drug development process. Depending on the problem, scientists may be forced to use several modeling tools that could increase model development time, IT costs and so on. Therefore it is desirable to have a single platform that allows setting up and running large-scale simulations for the models that have been developed with different modeling tools. We developed a workflow and a software platform in which a model file is compiled into a self-contained executable that is no longer dependent on the software that was used to create the model. At the same time the full model specifics is preserved by presenting all model parameters as input parameters for the executable. This platform was implemented as a model agnostic, therapeutic area agnostic and web-based application with a database back-end that can be used to configure, manage and execute large-scale simulations for multiple models by multiple users. The user interface is designed to be easily configurable to reflect the specifics of the model and the user’s particular needs and the back-end database has been implemented to store and manage all aspects of the systems, such as Models, Virtual Patients, User Interface Settings, and Results. The platform can be adapted and deployed on an existing cluster or cloud computing environment. Its use was demonstrated with a metabolic disease systems pharmacology model that simulates the effects of two antidiabetic drugs, metformin and fasiglifam, in type 2 diabetes mellitus patients.

  15. Biogeochemical Reactive Transport Model of the Redox Zone Experiment of the sp Hard Rock Laboratory in Sweden

    International Nuclear Information System (INIS)

    Molinero-Huguet, Jorge; Samper-Calvete, F. Javier; Zhang, Guoxiang; Yang, Changbing

    2004-01-01

    Underground facilities are being operated by several countries around the world for performing research and demonstration of the safety of deep radioactive waste repositories. The ''sp'' Hard Rock Laboratory is one such facility launched and operated by the Swedish Nuclear Fuel and Waste Management Company where various in situ experiments have been performed in fractured granites. One such experiment is the redox zone experiment, which aimed at evaluating the effects of the construction of an access tunnel on the hydrochemical conditions of a fracture zone. Dilution of the initially saline groundwater by fresh recharge water is the dominant process controlling the hydrochemical evolution of most chemical species, except for bicarbonate and sulfate, which unexpectedly increase with time. We present a numerical model of water flow, reactive transport, and microbial processes for the redox zone experiment. This model provides a plausible quantitatively based explanation for the unexpected evolution of bicarbonate and sulfate, reproduces the breakthrough curves of other reactive species, and is consistent with previous hydrogeological and solute transport models

  16. SP(6) X SU(2) and SO(8) X SU(2) - symmetric fermion-dynamic model of multinucleon systems

    International Nuclear Information System (INIS)

    Baktybaev, K.

    2007-01-01

    In last years a new approach describing collective states of multinucleon system on the base of their fermion dynamic symmetry was developed. Such fermion model is broad and logical one in comparison with the phenomenological model of interacting bosons. In cut fermion S- and D- pair spaces complicated nucleons interactions are approximating in that way so multinucleon system Hamiltonian becomes a simple function of fermion generators forming corresponding Lie algebra. Correlation fermion pairs are structured in such form so its operators of birth and destruction together with a set multiband operators are formed Sp(6) and SO(8) algebra of these pairs and SU(2)-algebra for so named anomalous pairs. For convenience at the model practical application to concrete systems the dynamical-symmetric Hamiltonian is writing by means of independent Casimir operators of subgroup are reductions of a large group. It is revealed, that observed Hamiltonians besides the known SU 3 , and SO 6 asymptotic borders have also more complicated 'vibration-like' borders SO 7 , SO 5 XSU 2 and SU 2 XSO 3 . In the paper both advantages and disadvantages of these borders and some its applications to specific nuclear systems are discussing

  17. Modeling the Test-Taking Motivation Construct through Investigation of Psychometric Properties of an Expectancy-Value-Based Questionnaire

    Science.gov (United States)

    Knekta, Eva; Eklöf, Hanna

    2015-01-01

    The aim of this study was to evaluate the psychometric properties of an expectancy-value-based questionnaire measuring five aspects of test-taking motivation (effort, expectancies, importance, interest, and test anxiety). The questionnaire was distributed to a sample of Swedish Grade 9 students taking a low-stakes (n = 1,047) or a high-stakes (n =…

  18. Investigation of market efficiency and Financial Stability between S&P 500 and London Stock Exchange: Monthly and yearly Forecasting of Time Series Stock Returns using ARMA model

    Science.gov (United States)

    Rounaghi, Mohammad Mahdi; Nassir Zadeh, Farzaneh

    2016-08-01

    We investigated the presence and changes in, long memory features in the returns and volatility dynamics of S&P 500 and London Stock Exchange using ARMA model. Recently, multifractal analysis has been evolved as an important way to explain the complexity of financial markets which can hardly be described by linear methods of efficient market theory. In financial markets, the weak form of the efficient market hypothesis implies that price returns are serially uncorrelated sequences. In other words, prices should follow a random walk behavior. The random walk hypothesis is evaluated against alternatives accommodating either unifractality or multifractality. Several studies find that the return volatility of stocks tends to exhibit long-range dependence, heavy tails, and clustering. Because stochastic processes with self-similarity possess long-range dependence and heavy tails, it has been suggested that self-similar processes be employed to capture these characteristics in return volatility modeling. The present study applies monthly and yearly forecasting of Time Series Stock Returns in S&P 500 and London Stock Exchange using ARMA model. The statistical analysis of S&P 500 shows that the ARMA model for S&P 500 outperforms the London stock exchange and it is capable for predicting medium or long horizons using real known values. The statistical analysis in London Stock Exchange shows that the ARMA model for monthly stock returns outperforms the yearly. ​A comparison between S&P 500 and London Stock Exchange shows that both markets are efficient and have Financial Stability during periods of boom and bust.

  19. PENERAPAN MODEL ARBITRAGE PRICING THEORY DENGAN PENDEKATAN VECTOR AUTOREGRESSION DALAM MENGESTIMASI EXPECTED RETURN SAHAM (Studi Kasus: Saham-Saham Kompas100 Periode 2010-2013

    Directory of Open Access Journals (Sweden)

    VIAN RISKA AYUNING TYAS

    2014-01-01

    Full Text Available The Arbitrage Pricing Theory (APT is an alternative model to estimate the price of securities based of arbitrage concept. In APT, the returns of securities are affected by several factors. This research is aimed to estimate the expected returns of securities using APT model and Vector Autoregressive model. There are ten stocks incorporated in Kompas100 index and four macroeconomic variables, these are inflation, exchange rates, the amountof circulate money (JUB, and theinterest rateof Bank Indonesia(SBI are applied in this research. The first step in using VAR is to test the stationary of the data using colerogram and the results indicate that all data are stationary. The second step is to select the optimal lag based on the smallest value of AIC. The Granger causality test shows that the LPKR stock is affected by the inflation and the exchange rate while the nine other stocks do not show the existence of the expected causality. The results of causality test are then estimated by the VAR models in order to obtain expected returnof macroeconomic factors. The expected return of macroeconomic factors obtained is used in the APT model, then the expected return stock LPKR is calculated. It shows that the expected return of LPKR is 3,340%

  20. PENERAPAN MODEL ARBITRAGE PRICING THEORY DENGAN PENDEKATAN VECTOR AUTOREGRESSION DALAM MENGESTIMASI EXPECTED RETURN SAHAM (Studi Kasus: Saham-Saham Kompas100 Periode 2010-2013

    Directory of Open Access Journals (Sweden)

    VIAN RISKA AYUNING TYAS

    2014-08-01

    Full Text Available The Arbitrage Pricing Theory (APT is an alternative model to estimate the price of securities based of arbitrage concept. In APT, the returns of securities are affected by several factors. This research is aimed to estimate the expected returns of securities using APT model and Vector Autoregressive model. There are ten stocks incorporated in Kompas100 index and four macroeconomic variables, these are inflation, exchange rates, the amountof circulate money (JUB, and theinterest rateof Bank Indonesia(SBI are applied in this research. The first step in using VAR is to test the stationary of the data using colerogram and the results indicate that all data are stationary. The second step is to select the optimal lag based on the smallest value of AIC. The Granger causality test shows that the LPKR stock is affected by the inflation and the exchange rate while the nine other stocks do not show the existence of the expected causality. The results of causality test are then estimated by the VAR models in order to obtain expected returnof macroeconomic factors. The expected return of macroeconomic factors obtained is used in the APT model, then the expected return stock LPKR is calculated. It shows that the expected return of LPKR is 3,340%

  1. Exact finite volume expectation values of \\overline{Ψ}Ψ in the massive Thirring model from light-cone lattice correlators

    Science.gov (United States)

    Hegedűs, Árpád

    2018-03-01

    In this paper, using the light-cone lattice regularization, we compute the finite volume expectation values of the composite operator \\overline{Ψ}Ψ between pure fermion states in the Massive Thirring Model. In the light-cone regularized picture, this expectation value is related to 2-point functions of lattice spin operators being located at neighboring sites of the lattice. The operator \\overline{Ψ}Ψ is proportional to the trace of the stress-energy tensor. This is why the continuum finite volume expectation values can be computed also from the set of non-linear integral equations (NLIE) governing the finite volume spectrum of the theory. Our results for the expectation values coming from the computation of lattice correlators agree with those of the NLIE computations. Previous conjectures for the LeClair-Mussardo-type series representation of the expectation values are also checked.

  2. Pyrolysis mechanism of microalgae Nannochloropsis sp. based on model compounds and their interaction

    International Nuclear Information System (INIS)

    Wang, Xin; Tang, Xiaohan; Yang, Xiaoyi

    2017-01-01

    Highlights: • Pyrolysis experiments were conducted by model compounds of algal components. • Interaction affected little bio-crude yield of model compounds co-pyrolysis. • Some interaction pathways between microalgae components were recommended. • N-heterocyclic compounds were further pyrolysis products of Maillard reaction products. • Surfactant synthesis (lipid-amino acids and lipid-glucose) between algal components. - Abstract: Pyrolysis is one of important pathways to convert microalgae to liquid biofuels and key components of microalgae have different chemical composition and structure, which provides a barrier for large-scale microalgae-based liquid biofuel application. Microalgae component pyrolysis mechanism should be researched to optimal pyrolysis process parameters. In this study, single pyrolysis and co-pyrolysis of microalgal components (model compounds castor oil, soybean protein and glucose) were conducted to reveal interaction between them by thermogrametric analysis and bio-crude evaluation. Castor oil (model compound of lipid) has higher pyrolysis temperature than other model compounds and has the maximum contribution to bio-crude formation. Bio-crude from soybean protein has higher N-heterocyclic compounds as well as phenols, which could be important aromatic hydrocarbon source during biorefineries and alternative aviation biofuel production. Potential interaction pathways based on model compounds are recommended including further decomposition of Maillard reaction products (MRPs) and surfactant synthesis, which indicate that glucose played an important role on pyrolysis of microalgal protein and lipid components. The results should provide necessary information for microalgae pyrolysis process optimization and large-scale pyrolysis reactor design.

  3. A nonparametric random coefficient approach for life expectancy growth using a hierarchical mixture likelihood model with application to regional data from North Rhine-Westphalia (Germany).

    Science.gov (United States)

    Böhning, Dankmar; Karasek, Sarah; Terschüren, Claudia; Annuß, Rolf; Fehr, Rainer

    2013-03-09

    Life expectancy is of increasing prime interest for a variety of reasons. In many countries, life expectancy is growing linearly, without any indication of reaching a limit. The state of North Rhine-Westphalia (NRW) in Germany with its 54 districts is considered here where the above mentioned growth in life expectancy is occurring as well. However, there is also empirical evidence that life expectancy is not growing linearly at the same level for different regions. To explore this situation further a likelihood-based cluster analysis is suggested and performed. The modelling uses a nonparametric mixture approach for the latent random effect. Maximum likelihood estimates are determined by means of the EM algorithm and the number of components in the mixture model are found on the basis of the Bayesian Information Criterion. Regions are classified into the mixture components (clusters) using the maximum posterior allocation rule. For the data analyzed here, 7 components are found with a spatial concentration of lower life expectancy levels in a centre of NRW, formerly an enormous conglomerate of heavy industry, still the most densely populated area with Gelsenkirchen having the lowest level of life expectancy growth for both genders. The paper offers some explanations for this fact including demographic and socio-economic sources. This case study shows that life expectancy growth is widely linear, but it might occur on different levels.

  4. Functional consequences of cocaine expectation: findings in a non-human primate model of cocaine self-administration.

    Science.gov (United States)

    Porrino, Linda J; Beveridge, Thomas J R; Smith, Hilary R; Nader, Michael A

    2016-05-01

    Exposure to stimuli and environments associated with drug use is considered one of the most important contributors to relapse among substance abusers. Neuroimaging studies have identified neural circuits underlying these responses in cocaine-dependent subjects. But these studies are often difficult to interpret because of the heterogeneity of the participants, substances abused, and differences in drug histories and social variables. Therefore, the goal of this study was to assess the functional effects of exposure to cocaine-associated stimuli in a non-human primate model of cocaine self-administration, providing precise control over these variables, with the 2-[(14) C]deoxyglucose method. Rhesus monkeys self-administered 0.3 mg/kg/injection cocaine (n = 4) under a fixed-interval 3-minute (FI 3-min) schedule of reinforcement (30 injections/session) for 100 sessions. Control animals (n = 4) underwent identical schedules of food reinforcement. Sessions were then discontinued for 30 days, after which time, monkeys were exposed to cocaine- or food-paired cues, and the 2-[(14) C]deoxyglucose experiment was conducted. The presentation of the cocaine-paired cues resulted in significant increases in functional activity within highly restricted circuits that included portions of the pre-commissural striatum, medial prefrontal cortex, rostral temporal cortex and limbic thalamus when compared with control animals presented with the food-paired cues. The presentation of cocaine-associated cues increased brain functional activity in contrast to the decreases observed after cocaine consumption. Furthermore, the topography of brain circuits engaged by the expectation of cocaine is similar to the distribution of effects during the earliest phases of cocaine self-administration, prior to the onset of neuroadaptations that accompany chronic cocaine exposure. © 2015 Society for the Study of Addiction.

  5. Genetic interaction motif finding by expectation maximization – a novel statistical model for inferring gene modules from synthetic lethality

    Directory of Open Access Journals (Sweden)

    Ye Ping

    2005-12-01

    Full Text Available Abstract Background Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership in a single protein complex may be inferred between genes that share synthetic lethal interaction partners than genes that are directly synthetic lethal. Probabilistic algorithms that identify gene modules based on motif discovery are highly appropriate for the analysis of synthetic lethal genetic interaction data and have great potential in integrative analysis of heterogeneous datasets. Results We have developed Genetic Interaction Motif Finding (GIMF, an algorithm for unsupervised motif discovery from synthetic lethal interaction data. Interaction motifs are characterized by position weight matrices and optimized through expectation maximization. Given a seed gene, GIMF performs a nonlinear transform on the input genetic interaction data and automatically assigns genes to the motif or non-motif category. We demonstrate the capacity to extract known and novel pathways for Saccharomyces cerevisiae (budding yeast. Annotations suggested for several uncharacterized genes are supported by recent experimental evidence. GIMF is efficient in computation, requires no training and automatically down-weights promiscuous genes with high degrees. Conclusion GIMF effectively identifies pathways from synthetic lethality data with several unique features. It is mostly suitable for building gene modules around seed genes. Optimal choice of one single model parameter allows construction of gene networks with different levels of confidence. The impact of hub genes the generic probabilistic framework of GIMF may be used to group other types of biological entities such as proteins based on stochastic motifs. Analysis of the strongest motifs discovered by the algorithm indicates that synthetic lethal interactions are depleted between genes within a motif, suggesting that synthetic

  6. Vacuum expectation values of Higgs scalars in a SU(2)/sub L/ x SU(2)/sub R/ x U(1) gauge model

    International Nuclear Information System (INIS)

    Kitazoe, T.; Mainland, G.B.; Tanaka, K.

    1979-01-01

    We determine the vacuum expectation values of the Higgs scalars within the framework of a six-quark SU(2)/sub L/ x SU(2)/sub R/ x U(1) gauge model after the imposition of discrete symmetries that are necessary in order to express the Cabibbo angle in terms of quark mass ratios and phases of the vacuum expectation values. We find both real and complex solutions for the vacuum expectation values depending on the relative values of the parameters in the Higgs potential

  7. Vacuum expectation values of Higgs scalars in a SU(2)/sub L/ X SU(2)/sub R/ X U(1) gauge model

    International Nuclear Information System (INIS)

    Kitazoe, T.; Mainland, G.B.; Tanaka, K.

    1978-01-01

    The vacuum expectation values of the Higgs scalars are determined within the framework of a six quark SU(2)/sub L/ x SU(2)/sub R/ x U(1) gauge model after the imposition of discrete symmetrics that are necessary in order to express the Cabibbo angle in terms of quark mass ratios and phases of the vacuum expectation values. Both real and complex solutions are found for the vacuum expectation values depending on the relative values of the parameters in the Higgs potential

  8. Bioeconomic of profit maximization of red tilapia (Oreochromis sp.) culture using polynomial growth model

    Science.gov (United States)

    Wijayanto, D.; Kurohman, F.; Nugroho, RA

    2018-03-01

    The research purpose was to develop a model bioeconomic of profit maximization that can be applied to red tilapia culture. The development of fish growth model used polynomial growth function. Profit maximization process used the first derivative of profit equation to time of culture equal to zero. This research has also developed the equations to estimate the culture time to reach the target size of the fish harvest. The research proved that this research model could be applied in the red tilapia culture. In the case of this study, red tilapia culture can achieve the maximum profit at 584 days and the profit of Rp. 28,605,731 per culture cycle. If used size target of 250 g, the culture of red tilapia need 82 days of culture time.

  9. 76 FR 36390 - Airworthiness Directives; The Boeing Company Model 747SP Series Airplanes

    Science.gov (United States)

    2011-06-22

    ... power control modules (PCM). This proposed AD was prompted by a report of a rudder hard-over event on a... rudder PCM manifold, which could result in a hard-over of the rudder surface leading to an increase in... of a Model 747-400 series airplane of a lower rudder hard-over event caused by a lower rudder PCM...

  10. Metabolic Rhythms of the Cyanobacterium Cyanothece sp ATCC 51142 Correlate with Modeled Dynamics of Circadian Clock

    Czech Academy of Sciences Publication Activity Database

    Červený, Jan; Nedbal, Ladislav

    2009-01-01

    Roč. 4, č. 24 (2009), s. 295-303 ISSN 0748-7304 R&D Projects: GA ČR(CZ) GA206/09/1284 Institutional research plan: CEZ:AV0Z60870520 Keywords : circadian clock * cyanobacteria * model * photosynthesis * respiration Subject RIV: CE - Biochemistry Impact factor: 4.418, year: 2009

  11. Modeling and Forecasting S&P 500 Volatility: Long Memory, Structural Breaks and Nonlinearity

    NARCIS (Netherlands)

    M.P.E. Martens (Martin); D.J.C. van Dijk (Dick); M.D. de Pooter (Michiel)

    2004-01-01

    textabstractThe sum of squared intraday returns provides an unbiased and almost error-free measure of ex-post volatility. In this paper we develop a nonlinear Autoregressive Fractionally Integrated Moving Average (ARFIMA) model for realized volatility, which accommodates level shifts,

  12. Model for analyzing growth kinetics of a slowly growing Mycobacterium sp

    International Nuclear Information System (INIS)

    Lambrecht, R.S.; Carriere, J.F.; Collins, M.T.

    1988-01-01

    This report describes a simple method for quantifying viable mycobacteria and for determining generation time. We used statistical models and computer analysis of growth curves generated for the slowly growing mycobacterium Mycobacterium paratuberculosis under controlled conditions to derive a mathematical formula relating the dependent variable, growth, to the independent variables, log10 number of organisms in the inoculum (inoculum size) and incubation time. Growth was measured by a radiometric method which detects 14 CO 2 release during metabolism of a 14 C-labeled substrate. The radiometric method allowed for early detection of growth and detected as few as three viable bacteria. The coefficient of variation between culture vials inoculated with the same number of M. paratuberculosis was 0.083. Radiometric measurements were highly correlated to spectrophotometric and plate count methods for measuring growth (r = 0.962 and 0.992, respectively). The proportion of the total variability explained by the model in a goodness of fit test was 0.9994. Application of the model to broth cultures provided accurate estimates of the number of M. paratuberculosis (standard error = 0.21, log10 scale) and the growth rate (coefficient of variation, 0.03). Generation time was observed to be dependent upon the number of organisms in the inoculum. The model accurately described all phases of growth of M. paratuberculosis and can likely be applied to other slowly growing microorganisms

  13. Choices and Changes: Eccles' Expectancy-Value Model and Upper-Secondary School Students' Longitudinal Reflections about Their Choice of a STEM Education

    Science.gov (United States)

    Lykkegaard, Eva; Ulriksen, Lars

    2016-01-01

    During the past 30 years, Eccles' comprehensive social-psychological Expectancy-Value Model of Motivated Behavioural Choices (EV-MBC model) has been proven suitable for studying educational choices related to Science, Technology, Engineering and/or Mathematics (STEM). The reflections of 15 students in their last year in upper-secondary school…

  14. Phenomenological Hamiltonian of Sp(2,R) model for heavy deformed nuclei

    International Nuclear Information System (INIS)

    Avramenko, V.I.; Asherova, R.M.; Filippov, G.F.; Smirnov, Yu.F.; Zajtsev, S.A.

    1985-01-01

    In the frame of the symplectic collective model, operating with the microscopical basic functions of irraducible representation of SU(3) groups the energy spectrum of collective excitation in 164 Kr nucleus is calculated. Also the aOsolute and relative values of probabilities E2-transitions between collective states are obtained. The indexes of SU(3) symmetry are chosen in correspondence with rules of Nillsson orbital occupation

  15. Model Pemilihan Moda Atas Pelayanan Monorel Jakarta Berdasarkan Data Stated Preference (SP)

    OpenAIRE

    Sjafruddin, Ade; Haryoyudanto, Apriadi; Wirahadikusumah, Reini D; Amalia, Nina

    2008-01-01

    The need for mass transportation urges the government of Jakarta to build a monorail system. Monorail will increase the capacity of public transportation system and give a new color to the urban transportation services. Users will have an additional mode choice and then make their preferences. User's behaviour when choosing mode can be modeled using Stated Preference data. By using Stated Preference, monorail can be compared objectively to existing modes, namely private car, AC bus, non-AC b...

  16. Aiptasia sp. larvae as a model to reveal mechanisms of symbiont selection in cnidarians

    KAUST Repository

    Wolfowicz, Iliona

    2016-09-01

    Symbiosis, defined as the persistent association between two distinct species, is an evolutionary and ecologically critical phenomenon facilitating survival of both partners in diverse habitats. The biodiversity of coral reef ecosystems depends on a functional symbiosis with photosynthetic dinoflagellates of the highly diverse genus Symbiodinium, which reside in coral host cells and continuously support their nutrition. The mechanisms underlying symbiont selection to establish a stable endosymbiosis in non-symbiotic juvenile corals are unclear. Here we show for the first time that symbiont selection patterns for larvae of two Acropora coral species and the model anemone Aiptasia are similar under controlled conditions. We find that Aiptasia larvae distinguish between compatible and incompatible symbionts during uptake into the gastric cavity and phagocytosis. Using RNA-Seq, we identify a set of candidate genes potentially involved in symbiosis establishment. Together, our data complement existing molecular resources to mechanistically dissect symbiont phagocytosis in cnidarians under controlled conditions, thereby strengthening the role of Aiptasia larvae as a powerful model for cnidarian endosymbiosis establishment.

  17. Heterokont predator Develorapax marinus gen. et sp. nov. – a model of the ochrophyte ancestor

    Directory of Open Access Journals (Sweden)

    Vladimir V. Aleoshin

    2016-08-01

    Full Text Available Heterotrophic lineages of Heterokonta (or stramenopiles, in contrast to a single monophyletic group of autotrophs, Ochrophyta, form several clades that independently branch off the heterokont stem lineage. The nearest neighbors of Ochrophyta in the phylogenetic tree appear to be almost exclusively bacterivorous, whereas the hypothesis of plastid acquisition by the ancestors of the ochrophyte lineage suggests an ability to engulf eukaryotic alga. In line with this hypothesis, the heteretrophic predator at the base of the ochrophyte lineage may be regarded as a model for the ochrophyte ancestor. Here we present a new genus and species of marine free-living heterotrophic heterokont Develorapax marinus, which falls into an isolated heterokont cluster, along with the marine flagellate Developayella elegans, and is able to engulf eukaryotic cells. Together with environmental sequences D. marinus and D. elegans form a class-level clade Developea nom. nov. represented by species adapted to different environmental conditions and with a wide geographical distribution. The position of Developea among Heterokonta in large-scale phylogenetic tree is discussed. We propose that members of the Developea clade represent a model for transition from bacterivory to a predatory feeding mode by selection for larger prey. Presumably, such transition in the grazing strategy is possible in the presence of bacterial biofilms, and has likely occured in the ochrophyte ancestor.

  18. Aiptasia sp. larvae as a model to reveal mechanisms of symbiont selection in cnidarians

    KAUST Repository

    Wolfowicz, Iliona; Baumgarten, Sebastian; Voss, Philipp A.; Hambleton, Elizabeth A.; Voolstra, Christian R.; Hatta, Masayuki; Guse, Annika

    2016-01-01

    Symbiosis, defined as the persistent association between two distinct species, is an evolutionary and ecologically critical phenomenon facilitating survival of both partners in diverse habitats. The biodiversity of coral reef ecosystems depends on a functional symbiosis with photosynthetic dinoflagellates of the highly diverse genus Symbiodinium, which reside in coral host cells and continuously support their nutrition. The mechanisms underlying symbiont selection to establish a stable endosymbiosis in non-symbiotic juvenile corals are unclear. Here we show for the first time that symbiont selection patterns for larvae of two Acropora coral species and the model anemone Aiptasia are similar under controlled conditions. We find that Aiptasia larvae distinguish between compatible and incompatible symbionts during uptake into the gastric cavity and phagocytosis. Using RNA-Seq, we identify a set of candidate genes potentially involved in symbiosis establishment. Together, our data complement existing molecular resources to mechanistically dissect symbiont phagocytosis in cnidarians under controlled conditions, thereby strengthening the role of Aiptasia larvae as a powerful model for cnidarian endosymbiosis establishment.

  19. Candidatus Sodalis melophagi sp. nov.: phylogenetically independent comparative model to the tsetse fly symbiont Sodalis glossinidius.

    Directory of Open Access Journals (Sweden)

    Tomáš Chrudimský

    Full Text Available Bacteria of the genus Sodalis live in symbiosis with various groups of insects. The best known member of this group, a secondary symbiont of tsetse flies Sodalis glossinidius, has become one of the most important models in investigating establishment and evolution of insect-bacteria symbiosis. It represents a bacterium in the early/intermediate state of the transition towards symbiosis, which allows for exploring such interesting topics as: usage of secretory systems for entering the host cell, tempo of the genome modification, and metabolic interaction with a coexisting primary symbiont. In this study, we describe a new Sodalis species which could provide a useful comparative model to the tsetse symbiont. It lives in association with Melophagus ovinus, an insect related to tsetse flies, and resembles S. glossinidius in several important traits. Similar to S. glossinidius, it cohabits the host with another symbiotic bacterium, the bacteriome-harbored primary symbiont of the genus Arsenophonus. As a typical secondary symbiont, Candidatus Sodalis melophagi infects various host tissues, including bacteriome. We provide basic morphological and molecular characteristics of the symbiont and show that these traits also correspond to the early/intermediate state of the evolution towards symbiosis. Particularly, we demonstrate the ability of the bacterium to live in insect cell culture as well as in cell-free medium. We also provide basic characteristics of type three secretion system and using three reference sequences (16 S rDNA, groEL and spaPQR region we show that the bacterium branched within the genus Sodalis, but originated independently of the two previously described symbionts of hippoboscoids. We propose the name Candidatus Sodalis melophagi for this new bacterium.

  20. Candidatus Sodalis melophagi sp. nov.: phylogenetically independent comparative model to the tsetse fly symbiont Sodalis glossinidius.

    Science.gov (United States)

    Chrudimský, Tomáš; Husník, Filip; Nováková, Eva; Hypša, Václav

    2012-01-01

    Bacteria of the genus Sodalis live in symbiosis with various groups of insects. The best known member of this group, a secondary symbiont of tsetse flies Sodalis glossinidius, has become one of the most important models in investigating establishment and evolution of insect-bacteria symbiosis. It represents a bacterium in the early/intermediate state of the transition towards symbiosis, which allows for exploring such interesting topics as: usage of secretory systems for entering the host cell, tempo of the genome modification, and metabolic interaction with a coexisting primary symbiont. In this study, we describe a new Sodalis species which could provide a useful comparative model to the tsetse symbiont. It lives in association with Melophagus ovinus, an insect related to tsetse flies, and resembles S. glossinidius in several important traits. Similar to S. glossinidius, it cohabits the host with another symbiotic bacterium, the bacteriome-harbored primary symbiont of the genus Arsenophonus. As a typical secondary symbiont, Candidatus Sodalis melophagi infects various host tissues, including bacteriome. We provide basic morphological and molecular characteristics of the symbiont and show that these traits also correspond to the early/intermediate state of the evolution towards symbiosis. Particularly, we demonstrate the ability of the bacterium to live in insect cell culture as well as in cell-free medium. We also provide basic characteristics of type three secretion system and using three reference sequences (16 S rDNA, groEL and spaPQR region) we show that the bacterium branched within the genus Sodalis, but originated independently of the two previously described symbionts of hippoboscoids. We propose the name Candidatus Sodalis melophagi for this new bacterium.

  1. Using sparse polynomial chaos expansions for the global sensitivity analysis of groundwater lifetime expectancy in a multi-layered hydrogeological model

    International Nuclear Information System (INIS)

    Deman, G.; Konakli, K.; Sudret, B.; Kerrou, J.; Perrochet, P.; Benabderrahmane, H.

    2016-01-01

    The study makes use of polynomial chaos expansions to compute Sobol' indices within the frame of a global sensitivity analysis of hydro-dispersive parameters in a simplified vertical cross-section of a segment of the subsurface of the Paris Basin. Applying conservative ranges, the uncertainty in 78 input variables is propagated upon the mean lifetime expectancy of water molecules departing from a specific location within a highly confining layer situated in the middle of the model domain. Lifetime expectancy is a hydrogeological performance measure pertinent to safety analysis with respect to subsurface contaminants, such as radionuclides. The sensitivity analysis indicates that the variability in the mean lifetime expectancy can be sufficiently explained by the uncertainty in the petrofacies, i.e. the sets of porosity and hydraulic conductivity, of only a few layers of the model. The obtained results provide guidance regarding the uncertainty modeling in future investigations employing detailed numerical models of the subsurface of the Paris Basin. Moreover, the study demonstrates the high efficiency of sparse polynomial chaos expansions in computing Sobol' indices for high-dimensional models. - Highlights: • Global sensitivity analysis of a 2D 15-layer groundwater flow model is conducted. • A high-dimensional random input comprising 78 parameters is considered. • The variability in the mean lifetime expectancy for the central layer is examined. • Sparse polynomial chaos expansions are used to compute Sobol' sensitivity indices. • The petrofacies of a few layers can sufficiently explain the response variance.

  2. Prioritizing child health interventions in Ethiopia: modeling impact on child mortality, life expectancy and inequality in age at death.

    Directory of Open Access Journals (Sweden)

    Kristine Husøy Onarheim

    Full Text Available BACKGROUND: The fourth Millennium Development Goal calls for a two-thirds reduction in under-5 mortality between 1990 and 2015. Under-5 mortality rate is declining, but many countries are still far from achieving the goal. Effective child health interventions that could reduce child mortality exist, but national decision-makers lack contextual information for priority setting in their respective resource-constrained settings. We estimate the potential health impact of increasing coverage of 14 selected health interventions on child mortality in Ethiopia (2011-2015. We also explore the impact on life expectancy and inequality in the age of death (Gini(health. METHODS AND FINDINGS: We used the Lives Saved Tool to estimate potential impact of scaling-up 14 health interventions in Ethiopia (2011-2015. Interventions are scaled-up to 1 government target levels, 2 90% coverage and 3 90% coverage of the five interventions with the highest impact. Under-5 mortality rate, neonatal mortality rate and deaths averted are primary outcome measures. We used modified life tables to estimate impact on life expectancy at birth and inequality in the age of death (Gini(health. Under-5 mortality rate declines from 101.0 in 2011 to 68.8, 42.1 and 56.7 per 1000 live births under these three scenarios. Prioritizing child health would also increase life expectancy at birth from expected 60.5 years in 2015 to 62.5, 64.2 and 63.4 years and reduce inequality in age of death (Gini(health substantially from 0.24 to 0.21, 0.18 and 0.19. CONCLUSIONS: The Millennium Development Goal for child health is reachable in Ethiopia. Prioritizing child health would also increase total life expectancy at birth and reduce inequality in age of death substantially (Gini(health.

  3. Mental models of adherence: parallels in perceptions, values, and expectations in adherence to prescribed home exercise programs and other personal regimens.

    Science.gov (United States)

    Rizzo, Jon; Bell, Alexandra

    2018-05-09

    A mental model is the collection of an individual's perceptions, values, and expectations about a particular aspect of their life, which strongly influences behaviors. This study explored orthopedic outpatients mental models of adherence to prescribed home exercise programs and how they related to mental models of adherence to other types of personal regimens. The study followed an interpretive description qualitative design. Data were collected via two semi-structured interviews. Interview One focused on participants prior experiences adhering to personal regimens. Interview Two focused on experiences adhering to their current prescribed home exercise program. Data analysis followed a constant comparative method. Findings revealed similarity in perceptions, values, and expectations that informed individuals mental models of adherence to personal regimens and prescribed home exercise programs. Perceived realized results, expected results, perceived social supports, and value of convenience characterized mental models of adherence. Parallels between mental models of adherence for prescribed home exercise and other personal regimens suggest that patients adherence behavior to prescribed routines may be influenced by adherence experiences in other aspects of their lives. By gaining insight into patients adherence experiences, values, and expectations across life domains, clinicians may tailor supports that enhance home exercise adherence. Implications for Rehabilitation A mental model is the collection of an individual's perceptions, values, and expectations about a particular aspect of their life, which is based on prior experiences and strongly influences behaviors. This study demonstrated similarity in orthopedic outpatients mental models of adherence to prescribed home exercise programs and adherence to personal regimens in other aspects of their lives. Physical therapists should inquire about patients non-medical adherence experiences, as strategies patients

  4. SP. Pescado

    Directory of Open Access Journals (Sweden)

    Renato Gendre

    2003-12-01

    Full Text Available Nell'occhiello di un articolo dal titolo Il Peru dei de[Jini rosa e de/la grande pioggia si legge: "da una partenza  in aereo al «pescado»  che ti  sfamera."1 Questa parola spagnola, giustamente chiusa tra caporali, a noi pare molto interes­ sante, perche, nonostante l'apparenza, non ha nulla da spartire sotto i1 profilo se­ mantico con l'it. pescato. lnfatti, tutti i piu importanti dizionari della lingua italiana, di ieri e di oggi, etimologici e non 2, registrano  accanto a pescata,  ii lemma pescato, 3 ma lo spiegano come "quantita di pesce catturato nel corso di una battuta o di una stagione di pesca",4 mentre lo sp. pescado  indica i1 "pesce (solo nel senso di: pesGe pescato da mangiare [...]".s

  5. Use of ecological niche modeling as a tool for predicting the potential distribution of Microcystis sp (cyanobacteria in the Aguamilpa Dam, Nayarit, Mexico

    Directory of Open Access Journals (Sweden)

    Enrique Martinez-Meyer

    2012-04-01

    Full Text Available Ecological niche modeling is an important tool to evaluate the spatial distribution of terrestrial species, however, its applicability has been little explored in the aquatic environment. Microcystis sp., a species of cyanobacteria, is widely recognized for its ability to produce a group of toxins known as microcystins, which can cause death of animals as fish, birds and mammals depending on the amount of toxin absorbed. Like any taxonomic group, cyanobacteria has environmental thresholds, therefore, a suitable ecological niche will define their distribution. This study was conducted in Aguamilpa Hydroelectric Reservoir, an artificial ecosystem that started operations in 1994. In this system we evaluated the potential distribution of Microcystis sp., by generating a prediction model based on the concept of ecological niche MAXENT, using a Digital Elevation Model in cells of 100 m x 100 m (1 ha spatial resolution and monitoring eleven physicochemical and biological variables and nutrients in water. The distribution maps were developed using ArcMap 9.2®. The results indicated that Microcystis sp., is distributed mainly in the upper tributary basin (Huaynamota basin during the dry season. There was less chance to find cyanobacteria in the entire system during the cold dry season, while during the warm dry season cyanobacteria was recognized at the confluence of two rivers. During the rainfall season there were no reports of cyanobacteria presence. This species is often associated with arising trophic processes of anthropogenic origin; therefore, attention is required in specific areas that have been identified in this work to improve Aguamilpa’s watershed management and restoration. It was also recognized the importance of phosphorus and nitrogen interaction, which determines the distribution of Microcystis sp., in the Aguamilpa Reservoir. The results of this study demonstrated that ecological niche modeling was a suitable tool to assess the

  6. Colobopsis explodens sp. n., model species for studies on “exploding ants” (Hymenoptera, Formicidae), with biological notes and first illustrations of males of the Colobopsis cylindrica group

    OpenAIRE

    Alice Laciny; Herbert Zettel; Alexey Kopchinskiy; Carina Pretzer; Anna Pal; Kamariah Abu Salim; Mohammad Javad Rahimi; Michaela Hoenigsberger; Linda Lim; Weeyawat Jaitrong; Irina S. Druzhinina

    2018-01-01

    A taxonomic description of all castes of Colobopsis explodens Laciny & Zettel, sp. n. from Borneo, Thailand, and Malaysia is provided, which serves as a model species for biological studies on “exploding ants” in Southeast Asia. The new species is a member of the Colobopsis cylindrica (COCY) group and falls into a species complex that has been repeatedly summarized under the name Colobopsis saundersi (Emery, 1889) (formerly Camponotus saundersi). The COCY species group is known under ...

  7. Colobopsis explodens sp. n., model species for studies on "exploding ants" (Hymenoptera, Formicidae), with biological notes and first illustrations of males of the Colobopsis cylindrica group

    OpenAIRE

    Laciny, Alice; Zettel, Herbert; Kopchinskiy, Alexey; Pretzer, Carina; Pal, Anna; Abu Salim, Kamariah; Javad Rahimi, Mohammad; Hoenigsberger, Michaela; Lim, Linda; Jaitrong, Weeyawat; Druzhinina, Irina S.

    2018-01-01

    A taxonomic description of all castes of Colobopsis explodens Laciny & Zettel, sp. n. from Borneo, Thailand, and Malaysia is provided, which serves as a model species for biological studies on "exploding ants" in Southeast Asia. The new species is a member of the Colobopsis cylindrica (COCY) group and falls into a species complex that has been repeatedly summarized under the name Colobopsis saundersi (Emery, 1889) (formerly Camponotus saundersi). The COCY species group is known under its vern...

  8. On-line detection of apnea/hypopnea events using SpO2 signal: a rule-based approach employing binary classifier models.

    Science.gov (United States)

    Koley, Bijoy Laxmi; Dey, Debangshu

    2014-01-01

    This paper presents an online method for automatic detection of apnea/hypopnea events, with the help of oxygen saturation (SpO2) signal, measured at fingertip by Bluetooth nocturnal pulse oximeter. Event detection is performed by identifying abnormal data segments from the recorded SpO2 signal, employing a binary classifier model based on a support vector machine (SVM). Thereafter the abnormal segment is further analyzed to detect different states within the segment, i.e., steady, desaturation, and resaturation, with the help of another SVM-based binary ensemble classifier model. Finally, a heuristically obtained rule-based system is used to identify the apnea/hypopnea events from the time-sequenced decisions of these classifier models. In the developmental phase, a set of 34 time domain-based features was extracted from the segmented SpO2 signal using an overlapped windowing technique. Later, an optimal set of features was selected on the basis of recursive feature elimination technique. A total of 34 subjects were included in the study. The results show average event detection accuracies of 96.7% and 93.8% for the offline and the online tests, respectively. The proposed system provides direct estimation of the apnea/hypopnea index with the help of a relatively inexpensive and widely available pulse oximeter. Moreover, the system can be monitored and accessed by physicians through LAN/WAN/Internet and can be extended to deploy in Bluetooth-enabled mobile phones.

  9. A new semi-supervised learning model combined with Cox and SP-AFT models in cancer survival analysis.

    Science.gov (United States)

    Chai, Hua; Li, Zi-Na; Meng, De-Yu; Xia, Liang-Yong; Liang, Yong

    2017-10-12

    Gene selection is an attractive and important task in cancer survival analysis. Most existing supervised learning methods can only use the labeled biological data, while the censored data (weakly labeled data) far more than the labeled data are ignored in model building. Trying to utilize such information in the censored data, a semi-supervised learning framework (Cox-AFT model) combined with Cox proportional hazard (Cox) and accelerated failure time (AFT) model was used in cancer research, which has better performance than the single Cox or AFT model. This method, however, is easily affected by noise. To alleviate this problem, in this paper we combine the Cox-AFT model with self-paced learning (SPL) method to more effectively employ the information in the censored data in a self-learning way. SPL is a kind of reliable and stable learning mechanism, which is recently proposed for simulating the human learning process to help the AFT model automatically identify and include samples of high confidence into training, minimizing interference from high noise. Utilizing the SPL method produces two direct advantages: (1) The utilization of censored data is further promoted; (2) the noise delivered to the model is greatly decreased. The experimental results demonstrate the effectiveness of the proposed model compared to the traditional Cox-AFT model.

  10. Pengaruh Beta Saham Terhadap Expected Return Dengan Model Capital Asset Pricing Pada Perusahaan Publik Di Bursa Efek Jakarta

    OpenAIRE

    Nasser, Etty M

    2007-01-01

    The objective of this research is to obtain empirical evidence of whether market beta has a significant influence on the expected return. This research examines 30 manufacturing companies listed in Jakarta Stock Exchange during 2001-2005 period. Data are mostly secondary data, obtained from Indonesian Capita! Market Directory and annual reports of the companies from 'Pusat Referensi Pasar Modal Indonesia' in Jakarta Stock Exchange. The statistical method used to test the hypothesis is multipl...

  11. PENGARUH BETA SAHAM TERHADAP EXPECTED RETURN DENGAN MODEL CAPITAL ASSET PRICING PADA PERUSAHAAN PUBLIK DI BURSA EFEK JAKARTA

    OpenAIRE

    Etty M. Nasser

    2007-01-01

    The objective of this research is to obtain empirical evidence of whether market beta has a significant influence on the expected return. This research examines 30 manufacturing companies listed in Jakarta Stock Exchange during 2001-2005 period. Data are mostly secondary data, obtained from Indonesian Capita! Market Directory and annual reports of the companies from 'Pusat Referensi Pasar Modal Indonesia' in Jakarta Stock Exchange. The statistical method used to test the hypothesis is multipl...

  12. A comparison of Reduced Life Expectancy (RLE) model with Haber's Rule to describe effects of exposure time on toxicity

    International Nuclear Information System (INIS)

    Verma, Vibha; Yu, Qiming J.; Connell, Des W.

    2015-01-01

    The Reduced Life Expectancy (RLE) Model (LC 50  = [ln(NLE) – ln(LT 50 )]/d) has been proposed as an alternative to Haber's Rule. The model is based on a linear relationship between LC 50 (Lethal Exposure Concentration) and lnLT 50 (Lethal Exposure Time) and uses NLE (Normal Life Expectancy) as a limiting point as well as a long term data point (where d is a constant). The purposes of this paper were to compare the RLE Model with Haber's Rule with available toxicity data and to evaluate the strengths and weaknesses of each approach. When LT 50 is relatively short and LC 50 is high, Haber's Rule is consistent with the RLE model. But the difference between the two was evident in the situation when LT 50 is relatively long and LC 50 is low where the RLE model is a marked departure from Haber's Rule. The RLE Model can be used to appropriately evaluate long term effects of exposure. - Highlights: • The strength and weakness of Haber's Rule in relation to the RLE model is needed. • Haber's Rule now used universally is quite inappropriate for environmental toxicity. • Normal life expectancy, a new parameter l is used to evaluate effects of exposure time on toxicity. • According to RLE model when LC 50 approaches zero, then LT 50  = Normal Life Expectancy. • The RLE model can be used to evaluate long term effects of exposure-accurately and easily. - The RLE approach is a more appropriate alternative particularly to evaluate long term effects of exposure. It can be easily used to estimate long term effects of exposure

  13. Predicting Student Grade Point Average at a Community College from Scholastic Aptitude Tests and from Measures Representing Three Constructs in Vroom's Expectancy Theory Model of Motivation.

    Science.gov (United States)

    Malloch, Douglas C.; Michael, William B.

    1981-01-01

    This study was designed to determine whether an unweighted linear combination of community college students' scores on standardized achievement tests and a measure of motivational constructs derived from Vroom's expectance theory model of motivation was predictive of academic success (grade point average earned during one quarter of an academic…

  14. Predicting who will major in a science discipline: Expectancy-value theory as part of an ecological model for studying academic communities

    Science.gov (United States)

    Sullins, Ellen S.; Hernandez, Delia; Fuller, Carol; Shiro Tashiro, Jay

    Research on factors that shape recruitment and retention in undergraduate science majors currently is highly fragmented and in need of an integrative research framework. Such a framework should incorporate analyses of the various levels of organization that characterize academic communities (i.e., the broad institutional level, the departmental level, and the student level), and should also provide ways to study the interactions occurring within and between these structural levels. We propose that academic communities are analogous to ecosystems, and that the research paradigms of modern community ecology can provide the necessary framework, as well as new and innovative approaches to a very complex area. This article also presents the results of a pilot study that demonstrates the promise of this approach at the student level. We administered a questionnaire based on expectancy-value theory to undergraduates enrolled in introductory biology courses. Itself an integrative approach, expectancy-value theory views achievement-related behavior as a joint function of the person's expectancy of success in the behavior and the subjective value placed on such success. Our results indicated: (a) significant gender differences in the underlying factor structures of expectations and values related to the discipline of biology, (b) expectancy-value factors significantly distinguished biology majors from nonmajors, and (c) expectancy-value factors significantly predicted students' intent to enroll in future biology courses. We explore the expectancy-value framework as an operationally integrative framework in our ecological model for studying academic communities, especially in the context of assessing the underrepresentation of women and minorities in the sciences. Future research directions as well as practical implications are also discussed.

  15. Evaluating an integrated pilot model for post-treatment of RAP effluent using Spirodela Sp. Evaluación de un modelo piloto integrado para postratamiento del efluente del RAP utilizando Spirodela sp.

    Directory of Open Access Journals (Sweden)

    Aguilar Acevedo Fernanda

    2006-12-01

    Full Text Available

    Integrated residual water treatment systems try to reduce organic matter and nutrients and reuse by-produets generated during the process. An integrated pilot model was constructed with Spirodela sp. to complement the Bolivariana University's current residual water treatment plant's efficieney in removing nutrients. This was evaluated for its efficieney in removing nutrients (ammoniacal nitrogen and phosphorus and total and faecal coliforms using different depths of water. 77.07% efficieney was obtained for ammoniacal nitrogen, 97.10% for total phosphorus, 98.56% for faecal coliforms and 96.4% for total coliforms.

    Key words: biological treatment, residual water, nutrient removal.

    Los sistemas integrados de tratamiento de aguas residuales buscan la disminución de materias orgánicas y nutrientes, además de la reutilización de los subproductos generados en el proceso. Para complementar la eficiencia de remoción de nutrientes del actual tratamiento de las aguas residuales de la Universidad Pontificia Bolivariana Bucaramanga se construyó un modelo piloto integrado con Spirodela sp., el cual fue evaluado para medir la eficiencia en remoción de nutrientes (nitrógeno y fósforo, coliformes totales y fecales, con diferentes alturas de lámina de agua; los resultados reportaron eficiencias hasta de 77.07% para nitrógeno amoniacal, 97.10% fósforo total, 98.56% coliformes fecales y 96.4% coliformes totales.

    Palabras clave: aguas residuales, tratamiento biológico, remoción de nutrientes.

  16. Modeling Pathways of Character Development across the First Three Decades of Life: An Application of Integrative Data Analysis Techniques to Understanding the Development of Hopeful Future Expectations.

    Science.gov (United States)

    Callina, Kristina Schmid; Johnson, Sara K; Tirrell, Jonathan M; Batanova, Milena; Weiner, Michelle B; Lerner, Richard M

    2017-06-01

    There were two purposes of the present research: first, to add to scholarship about a key character virtue, hopeful future expectations; and second, to demonstrate a recent innovation in longitudinal methodology that may be especially useful in enhancing the understanding of the developmental course of hopeful future expectations and other character virtues that have been the focus of recent scholarship in youth development. Burgeoning interest in character development has led to a proliferation of short-term, longitudinal studies on character. These data sets are sometimes limited in their ability to model character development trajectories due to low power or relatively brief time spans assessed. However, the integrative data analysis approach allows researchers to pool raw data across studies in order to fit one model to an aggregated data set. The purpose of this article is to demonstrate the promises and challenges of this new tool for modeling character development. We used data from four studies evaluating youth character strengths in different settings to fit latent growth curve models of hopeful future expectations from participants aged 7 through 26 years. We describe the analytic strategy for pooling the data and modeling the growth curves. Implications for future research are discussed in regard to the advantages of integrative data analysis. Finally, we discuss issues researchers should consider when applying these techniques in their own work.

  17. CEO expectation: the Star Wars materiel manager of the 1990s, or C-3PO as role model.

    Science.gov (United States)

    Zenty, T F; Olson, M R

    1993-05-01

    Materiel-intensive expenditures account for a significant portion of all hospital costs, second only to salaries and wages, yet materiel managers may often be overlooked as key members of the management team. This is alarming since the potential exists for materiel managers to impact annual savings of hundreds of thousands of dollars by operating efficient departments. Materiel managers have a tremendous opportunity to enhance their image and improve hospital productivity in the coming decade. The challenges of the 1990s will stretch materiel managers' skills toward enhancing their professionalism and achieving the expectations of themselves and top management. If materiel managers will effectively utilize (C3)PO they will increase their educational levels, continue to learn new skills, maintain a customer-oriented management style, exercise creativity, develop and adhere to standards, and be proactive in their responsibilities. The benefits of their success will be felt by patients, hospitals, the industry, and materiel managers everywhere.

  18. Colobopsis explodens sp. n., model species for studies on “exploding ants” (Hymenoptera, Formicidae), with biological notes and first illustrations of males of the Colobopsis cylindrica group

    Science.gov (United States)

    Laciny, Alice; Zettel, Herbert; Kopchinskiy, Alexey; Pretzer, Carina; Pal, Anna; Salim, Kamariah Abu; Rahimi, Mohammad Javad; Hoenigsberger, Michaela; Lim, Linda; Jaitrong, Weeyawat; Druzhinina, Irina S.

    2018-01-01

    Abstract A taxonomic description of all castes of Colobopsis explodens Laciny & Zettel, sp. n. from Borneo, Thailand, and Malaysia is provided, which serves as a model species for biological studies on “exploding ants” in Southeast Asia. The new species is a member of the Colobopsis cylindrica (COCY) group and falls into a species complex that has been repeatedly summarized under the name Colobopsis saundersi (Emery, 1889) (formerly Camponotus saundersi). The COCY species group is known under its vernacular name “exploding ants” for a unique behaviour: during territorial combat, workers of some species sacrifice themselves by rupturing their gaster and releasing sticky and irritant contents of their hypertrophied mandibular gland reservoirs to kill or repel rivals. This study includes first illustrations and morphometric characterizations of males of the COCY group: Colobopsis explodens Laciny & Zettel, sp. n. and Colobopsis badia (Smith, 1857). Characters of male genitalia and external morphology are compared with other selected taxa of Camponotini. Preliminary notes on the biology of C. explodens Laciny & Zettel, sp. n. are provided. To fix the species identity of the closely related C. badia, a lectotype from Singapore is designated. The following taxonomic changes within the C. saundersi complex are proposed: Colobopsis solenobia (Menozzi, 1926), syn. n. and Colobopsis trieterica (Menozzi, 1926), syn. n. are synonymized with Colobopsis corallina Roger, 1863, a common endemic species of the Philippines. Colobopsis saginata Stitz, 1925, stat. n., hitherto a subspecies of C. badia, is raised to species level. PMID:29706783

  19. Colobopsis explodens sp. n., model species for studies on "exploding ants" (Hymenoptera, Formicidae), with biological notes and first illustrations of males of the Colobopsis cylindrica group.

    Science.gov (United States)

    Laciny, Alice; Zettel, Herbert; Kopchinskiy, Alexey; Pretzer, Carina; Pal, Anna; Salim, Kamariah Abu; Rahimi, Mohammad Javad; Hoenigsberger, Michaela; Lim, Linda; Jaitrong, Weeyawat; Druzhinina, Irina S

    2018-01-01

    A taxonomic description of all castes of Colobopsis explodens Laciny & Zettel, sp. n. from Borneo, Thailand, and Malaysia is provided, which serves as a model species for biological studies on "exploding ants" in Southeast Asia. The new species is a member of the Colobopsis cylindrica (COCY) group and falls into a species complex that has been repeatedly summarized under the name Colobopsis saundersi (Emery, 1889) (formerly Camponotus saundersi ). The COCY species group is known under its vernacular name "exploding ants" for a unique behaviour: during territorial combat, workers of some species sacrifice themselves by rupturing their gaster and releasing sticky and irritant contents of their hypertrophied mandibular gland reservoirs to kill or repel rivals. This study includes first illustrations and morphometric characterizations of males of the COCY group: Colobopsis explodens Laciny & Zettel, sp. n. and Colobopsis badia (Smith, 1857). Characters of male genitalia and external morphology are compared with other selected taxa of Camponotini. Preliminary notes on the biology of C. explodens Laciny & Zettel, sp. n. are provided. To fix the species identity of the closely related C. badia , a lectotype from Singapore is designated. The following taxonomic changes within the C. saundersi complex are proposed: Colobopsis solenobia (Menozzi, 1926), syn. n. and Colobopsis trieterica (Menozzi, 1926), syn. n. are synonymized with Colobopsis corallina Roger, 1863, a common endemic species of the Philippines. Colobopsis saginata Stitz, 1925, stat. n ., hitherto a subspecies of C. badia , is raised to species level.

  20. Colobopsis explodens sp. n., model species for studies on “exploding ants” (Hymenoptera, Formicidae, with biological notes and first illustrations of males of the Colobopsis cylindrica group

    Directory of Open Access Journals (Sweden)

    Alice Laciny

    2018-04-01

    Full Text Available A taxonomic description of all castes of Colobopsis explodens Laciny & Zettel, sp. n. from Borneo, Thailand, and Malaysia is provided, which serves as a model species for biological studies on “exploding ants” in Southeast Asia. The new species is a member of the Colobopsis cylindrica (COCY group and falls into a species complex that has been repeatedly summarized under the name Colobopsis saundersi (Emery, 1889 (formerly Camponotus saundersi. The COCY species group is known under its vernacular name “exploding ants” for a unique behaviour: during territorial combat, workers of some species sacrifice themselves by rupturing their gaster and releasing sticky and irritant contents of their hypertrophied mandibular gland reservoirs to kill or repel rivals. This study includes first illustrations and morphometric characterizations of males of the COCY group: Colobopsis explodens Laciny & Zettel, sp. n. and Colobopsis badia (Smith, 1857. Characters of male genitalia and external morphology are compared with other selected taxa of Camponotini. Preliminary notes on the biology of C. explodens Laciny & Zettel, sp. n. are provided. To fix the species identity of the closely related C. badia, a lectotype from Singapore is designated. The following taxonomic changes within the C. saundersi complex are proposed: Colobopsis solenobia (Menozzi, 1926, syn. n. and Colobopsis trieterica (Menozzi, 1926, syn. n. are synonymized with Colobopsis corallina Roger, 1863, a common endemic species of the Philippines. Colobopsis saginata Stitz, 1925, stat. n., hitherto a subspecies of C. badia, is raised to species level.

  1. Reservation wages, expected wages and unemployment

    OpenAIRE

    Brown, S; Taylor, K

    2013-01-01

    We model unemployment duration, reservation and expected wages simultaneously for individuals not in work, where wage expectations are identified via an exogenous policy shock. The policy shock increased expected wages, which were found to be positively associated with reservation wages.

  2. Spiking the expectancy profiles

    DEFF Research Database (Denmark)

    Hansen, Niels Chr.; Loui, Psyche; Vuust, Peter

    Melodic expectations have long been quantified using expectedness ratings. Motivated by statistical learning and sharper key profiles in musicians, we model musical learning as a process of reducing the relative entropy between listeners' prior expectancy profiles and probability distributions...... of a given musical style or of stimuli used in short-term experiments. Five previous probe-tone experiments with musicians and non-musicians are revisited. Exp. 1-2 used jazz, classical and hymn melodies. Exp. 3-5 collected ratings before and after exposure to 5, 15 or 400 novel melodies generated from...... a finite-state grammar using the Bohlen-Pierce scale. We find group differences in entropy corresponding to degree and relevance of musical training and within-participant decreases after short-term exposure. Thus, whereas inexperienced listeners make high-entropy predictions by default, statistical...

  3. Draft genome sequences of six neonatal meningitis-causing escherichia coli isolates (SP-4, SP-5, SP-13, SP-16, SP-46, and SP-65)

    Science.gov (United States)

    Neonatal meningitis Escherichia coli isolates (SP-4, SP-5, SP-13, SP-16, SP-46, and SP-65) were recovered from infants in the Netherlands from 1989 to 1997. Here, we report the draft genome sequences for these six E. coli isolates, which are currently being used to validate food safety processing te...

  4. Reconstruction and in silico analysis of an Actinoplanes sp. SE50/110 genome-scale metabolic model for acarbose production

    Directory of Open Access Journals (Sweden)

    Yali eWang

    2015-06-01

    Full Text Available Actinoplanes sp. SE50/110 produces the -glucosidase inhibitor acarbose, which is used to treat type 2 diabetes mellitus. To obtain a comprehensive understanding of its cellular metabolism, a genome-scale metabolic model of strain SE50/110, iYLW1028, was reconstructed on the bases of the genome annotation, biochemical databases, and extensive literature mining. Model iYLW1028 comprises 1028 genes, 1128 metabolites and 1219 reactions. 122 and 81 genes were essential for cell growth on acarbose synthesis and sucrose media, respectively, and the acarbose biosynthetic pathway in SE50/110 was expounded completely. Based on model predictions, the addition of arginine and histidine to the media increased acarbose production by 78% and 59%, respectively. Additionally, dissolved oxygen has a great effect on acarbose production based on model predictions. Furthermore, genes to be overexpressed for the overproduction of acarbose were identified, and the deletion of treY eliminated the formation of by-product component C. Model iYLW1028 is a useful platform for optimizing and systems metabolic engineering for acarbose production in Actinoplanes sp. SE50/110.

  5. Heavy Metal Adsorption onto Kappaphycus sp. from Aqueous Solutions: The Use of Error Functions for Validation of Isotherm and Kinetics Models.

    Science.gov (United States)

    Rahman, Md Sayedur; Sathasivam, Kathiresan V

    2015-01-01

    Biosorption process is a promising technology for the removal of heavy metals from industrial wastes and effluents using low-cost and effective biosorbents. In the present study, adsorption of Pb(2+), Cu(2+), Fe(2+), and Zn(2+) onto dried biomass of red seaweed Kappaphycus sp. was investigated as a function of pH, contact time, initial metal ion concentration, and temperature. The experimental data were evaluated by four isotherm models (Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich) and four kinetic models (pseudo-first-order, pseudo-second-order, Elovich, and intraparticle diffusion models). The adsorption process was feasible, spontaneous, and endothermic in nature. Functional groups in the biomass involved in metal adsorption process were revealed as carboxylic and sulfonic acids and sulfonate by Fourier transform infrared analysis. A total of nine error functions were applied to validate the models. We strongly suggest the analysis of error functions for validating adsorption isotherm and kinetic models using linear methods. The present work shows that the red seaweed Kappaphycus sp. can be used as a potentially low-cost biosorbent for the removal of heavy metal ions from aqueous solutions. Further study is warranted to evaluate its feasibility for the removal of heavy metals from the real environment.

  6. Heterogeneous inflation expectations and learning

    OpenAIRE

    Madeira, Carlos; Zafar, Basit

    2012-01-01

    Using the panel component of the Michigan Survey of Consumers, we estimate a learning model of inflation expectations, allowing for heterogeneous use of both private information and lifetime inflation experience. “Life-experience inflation” has a significant impact on individual expectations, but only for one-year-ahead inflation. Public information is substantially more relevant for longer-horizon expectations. Even controlling for life-experience inflation and public information, idiosyncra...

  7. Comparison of rSP-C surfactant with natural and synthetic surfactants after late treatment in a rat model of the acute respiratory distress syndrome

    Science.gov (United States)

    Häfner, Dietrich; Germann, Paul-Georg; Hauschke, Dieter

    1998-01-01

    In a previous paper we showed that an SP-C containing surfactant preparation has similar activity as bovine-derived surfactants in a rat lung lavage model of the adult respiratory distress syndrome. In this study surfactant was given ten minutes after the last lavage (early treatment). In the present investigation we were interested how different surfactant preparations behave when they are administered 1 h after the last lavage (late treatment). Four protein containing surfactants (rSP-C surfactant, bLES, Infasurf and Survanta) were compared with three protein-free surfactants (ALEC, Exosurf and the phospholipid (PL) mixture of the rSP-C surfactant termed PL surfactant) with respect to their ability to improve gas exchange in this more stringent model when surfactant is given one hour after the last lavage. For better comparison of the surfactants the doses were related to phospholipids. The surfactants were given at doses of 25, 50 and 100 mg kg−1 body weight. The surfactants were compared to an untreated control group that was only ventilated for the whole experimental period. Tracheotomized rats (8–12 per dose and surfactant) were pressure-controlled ventilated (Siemens Servo Ventilator 900C) with 100% oxygen at a respiratory rate of 30 breaths min−1, inspiration expiration ratio of 1 : 2, peak inspiratory pressure of 28 cmH2O at positive endexpiratory pressure (PEEP) of 8 cmH2O. Animals were ventilated for one hour after the last lavage and thereafter the surfactants were intratracheally instilled. During the whole experimental period the ventilation was not changed. Partial arterial oxygen pressures (PaO2, mmHg) at 30 min and 120 min after treatment were used for statistical comparison. All protein containing surfactants caused a dose-dependent increase of the reduced PaO2 values at 30 min after treatment. The protein-free surfactants showed only weak dose-dependent increase in PaO2 values at this time. This difference between the

  8. Robust estimation of the expected survival probabilities from high-dimensional Cox models with biomarker-by-treatment interactions in randomized clinical trials

    Directory of Open Access Journals (Sweden)

    Nils Ternès

    2017-05-01

    Full Text Available Abstract Background Thanks to the advances in genomics and targeted treatments, more and more prediction models based on biomarkers are being developed to predict potential benefit from treatments in a randomized clinical trial. Despite the methodological framework for the development and validation of prediction models in a high-dimensional setting is getting more and more established, no clear guidance exists yet on how to estimate expected survival probabilities in a penalized model with biomarker-by-treatment interactions. Methods Based on a parsimonious biomarker selection in a penalized high-dimensional Cox model (lasso or adaptive lasso, we propose a unified framework to: estimate internally the predictive accuracy metrics of the developed model (using double cross-validation; estimate the individual survival probabilities at a given timepoint; construct confidence intervals thereof (analytical or bootstrap; and visualize them graphically (pointwise or smoothed with spline. We compared these strategies through a simulation study covering scenarios with or without biomarker effects. We applied the strategies to a large randomized phase III clinical trial that evaluated the effect of adding trastuzumab to chemotherapy in 1574 early breast cancer patients, for which the expression of 462 genes was measured. Results In our simulations, penalized regression models using the adaptive lasso estimated the survival probability of new patients with low bias and standard error; bootstrapped confidence intervals had empirical coverage probability close to the nominal level across very different scenarios. The double cross-validation performed on the training data set closely mimicked the predictive accuracy of the selected models in external validation data. We also propose a useful visual representation of the expected survival probabilities using splines. In the breast cancer trial, the adaptive lasso penalty selected a prediction model with 4

  9. An Enumerative Combinatorics Model for Fragmentation Patterns in RNA Sequencing Provides Insights into Nonuniformity of the Expected Fragment Starting-Point and Coverage Profile.

    Science.gov (United States)

    Prakash, Celine; Haeseler, Arndt Von

    2017-03-01

    RNA sequencing (RNA-seq) has emerged as the method of choice for measuring the expression of RNAs in a given cell population. In most RNA-seq technologies, sequencing the full length of RNA molecules requires fragmentation into smaller pieces. Unfortunately, the issue of nonuniform sequencing coverage across a genomic feature has been a concern in RNA-seq and is attributed to biases for certain fragments in RNA-seq library preparation and sequencing. To investigate the expected coverage obtained from fragmentation, we develop a simple fragmentation model that is independent of bias from the experimental method and is not specific to the transcript sequence. Essentially, we enumerate all configurations for maximal placement of a given fragment length, F, on transcript length, T, to represent every possible fragmentation pattern, from which we compute the expected coverage profile across a transcript. We extend this model to incorporate general empirical attributes such as read length, fragment length distribution, and number of molecules of the transcript. We further introduce the fragment starting-point, fragment coverage, and read coverage profiles. We find that the expected profiles are not uniform and that factors such as fragment length to transcript length ratio, read length to fragment length ratio, fragment length distribution, and number of molecules influence the variability of coverage across a transcript. Finally, we explore a potential application of the model where, with simulations, we show that it is possible to correctly estimate the transcript copy number for any transcript in the RNA-seq experiment.

  10. Introduction to the SP theory of intelligence

    OpenAIRE

    Wolff, J Gerard

    2018-01-01

    This article provides a brief introduction to the "Theory of Intelligence" and its realisation in the "SP Computer Model". The overall goal of the SP programme of research, in accordance with long-established principles in science, has been the simplification and integration of observations and concepts across artificial intelligence, mainstream computing, mathematics, and human learning, perception, and cognition. In broad terms, the SP system is a brain-like system that takes in "New" infor...

  11. Expected Term Structures

    DEFF Research Database (Denmark)

    Buraschi, Andrea; Piatti, Ilaria; Whelan, Paul

    We construct and study the cross-sectional properties of survey-based bond risk premia and compare them to their traditional statistical counterparts. We document large heterogeneity in skill, identify top forecasters, and learn about the importance of subjective risk premia in long-term bonds...... dynamics. The consensus is not a sufficient statistics of the cross-section of expectations and we propose an alternative real-time aggregate measure of risk premia consistent with Friedmans market selection hypothesis. We then use this measure to evaluate structural models and find support...

  12. Modeling the effects of multicontextual physics instruction on learner expectations and understanding of force and motion systems

    Science.gov (United States)

    Deese Becht, Sara-Maria Francis

    1999-11-01

    The purpose of this study is two-fold involving both practical and theoretical modeling components. The practical component, an experiential-learning phase, investigated a study population for effects that increasing levels of multicontextual physics activities have on student understanding of Newtonian systems of motion. This contextual-learning model measured learner convictions and non-response gaps and analyzed learner response trends on context, technology, challenge, growth, and success. The theoretical component, a model-building phase, designed a dynamic-knowing model for learning along a range of experiential tasks, from low to high context, monitored for indicators of learning in science and mathematics: learner academic performance and ability, learner control and academic attitude, and a learner non- response gap. This knowing model characterized a learner's process-of-knowing on a less to more expert- like learner-response continuum using performance and perspective indices associated with level of contextual- imagery referent system. Data for the contextual-learning model were collected on 180 secondary subjects: 72 middle and 108 high, with 36 physics subjects as local experts. Subjects were randomly assigned to one of three experimental groups differing only on context level of force and motion activities. Three levels of information were presented through context-based tasks: momentum constancy as inertia, momentum change as impulse, and momentum rate of change as force. The statistical analysis used a multi-level factorial design with repeated measures and discriminate analysis of response-conviction items. Subject grouping criteria included school level, ability level in science and mathematics, gender and race. Assessment criteria used pre/post performance scores, confidence level in physics concepts held, and attitude towards science, mathematics, and technology. Learner indices were computed from logit- transforms applied to learner outcomes

  13. Choices and Changes: Eccles’ Expectancy-Value Model and Upper-Secondary School Students’ Longitudinal Reflections about their Choice of a STEM Education

    DEFF Research Database (Denmark)

    Lykkegaard, Eva; Ulriksen, Lars

    2016-01-01

    During the past 30 years, Eccles’ comprehensive social-psychological Expectancy-Value Model of Motivated Behavioural Choices (EV-MBC model) has been proven suitable for studying educational choices related to Science, Technology, Engineering and/or Mathematics (STEM). The reflections of 15 students...... in their last year in upper-secondary school concerning their choice of tertiary education were examined using quantitative EV-MBC surveys and repeated qualitative interviews. This article presents the analyses of three cases in detail. The analytical focus was whether the factors indicated in the EV-MBC model......, and that significant changes in the students’ reflections were not captured by the factors of the EV-MBC model. This questions the validity of the EVMBC surveys. Moreover, the quantitative factors from the EV-MBC model did not sufficiently explain students’ dynamical educational choice processes where students...

  14. EREM: Parameter Estimation and Ancestral Reconstruction by Expectation-Maximization Algorithm for a Probabilistic Model of Genomic Binary Characters Evolution

    Directory of Open Access Journals (Sweden)

    Liran Carmel

    2010-01-01

    Full Text Available Evolutionary binary characters are features of species or genes, indicating the absence (value zero or presence (value one of some property. Examples include eukaryotic gene architecture (the presence or absence of an intron in a particular locus, gene content, and morphological characters. In many studies, the acquisition of such binary characters is assumed to represent a rare evolutionary event, and consequently, their evolution is analyzed using various flavors of parsimony. However, when gain and loss of the character are not rare enough, a probabilistic analysis becomes essential. Here, we present a comprehensive probabilistic model to describe the evolution of binary characters on a bifurcating phylogenetic tree. A fast software tool, EREM, is provided, using maximum likelihood to estimate the parameters of the model and to reconstruct ancestral states (presence and absence in internal nodes and events (gain and loss events along branches.

  15. EREM: Parameter Estimation and Ancestral Reconstruction by Expectation-Maximization Algorithm for a Probabilistic Model of Genomic Binary Characters Evolution.

    Science.gov (United States)

    Carmel, Liran; Wolf, Yuri I; Rogozin, Igor B; Koonin, Eugene V

    2010-01-01

    Evolutionary binary characters are features of species or genes, indicating the absence (value zero) or presence (value one) of some property. Examples include eukaryotic gene architecture (the presence or absence of an intron in a particular locus), gene content, and morphological characters. In many studies, the acquisition of such binary characters is assumed to represent a rare evolutionary event, and consequently, their evolution is analyzed using various flavors of parsimony. However, when gain and loss of the character are not rare enough, a probabilistic analysis becomes essential. Here, we present a comprehensive probabilistic model to describe the evolution of binary characters on a bifurcating phylogenetic tree. A fast software tool, EREM, is provided, using maximum likelihood to estimate the parameters of the model and to reconstruct ancestral states (presence and absence in internal nodes) and events (gain and loss events along branches).

  16. Expected for acquisition movement exercise is more effective for functional recovery than simple exercise in a rat model of hemiplegia

    OpenAIRE

    Ikeda, Satoshi; Ohwatashi, Akihiko; Harada, Katsuhiro; Kamikawa, Yurie; Yoshida, Akira

    2013-01-01

    Background and purpose The use of novel rehabilitative approaches for effecting functional recovery following stroke is controversial. Effects of different but effective rehabilitative interventions in the hemiplegic patient are not clear. We studied the effects of different rehabilitative approaches on functional recovery in the rat photochecmical cerebral infarction model. Methods Twenty-four male Wistar rats aged 8?weeks were used. The cranial bone was exposed under deep anesthesia. Rose b...

  17. Silicon detectors: Damage, modelling and expected long-time behaviour in physics experiments at ultra high energy

    International Nuclear Information System (INIS)

    Lazanu, Ionel; Lazanu, Sorina

    2007-01-01

    In this contribution, the structural modifications of the material and the degradation of devices is modelled and compared with the experimental data for more resistivities, temperatures, crystal orientations and oxygen concentrations, considering the existence of the new primary fourfold coordinated defect, besides the vacancy and the interstitial. Some estimations of the behaviour of detectors in specific environments at the next generations of high-energy physics experiments as LHC, SLHC, VLHC, or ULHC are done

  18. Laser-Induced Thermal Acoustics Theory and Expected Experimental Errors when Applied to a Scramjet Isolator Model

    Science.gov (United States)

    Middleton, Troy F.; Balla, Robert Jeffrey; Baurle, Robert A.; Wilson, Lloyd G.

    2011-01-01

    A scramjet isolator model test apparatus is being assembled in the Isolator Dynamics Research Lab (IDRL) at the NASA Langley Research Center in Hampton, Virginia. The test apparatus is designed to support multiple measurement techniques for investigating the flow field in a scramjet isolator model. The test section is 1-inch high by 2-inch wide by 24-inch long and simulates a scramjet isolator with an aspect ratio of two. Unheated, dry air at a constant stagnation pressure and temperature is delivered to the isolator test section through a Mach 2.5 planar nozzle. The isolator test section is mechanically back-pressured to contain the resulting shock train within the 24-inch isolator length and supports temperature, static pressure, and high frequency pressure measurements at the wall. Additionally, nonintrusive methods including laser-induced thermal acoustics (LITA), spontaneous Raman scattering, particle image velocimetry, and schlieren imaging are being incorporated to measure off-wall fluid dynamic, thermodynamic, and transport properties of the flow field. Interchangeable glass and metallic sidewalls and optical access appendages permit making multiple measurements simultaneously. The measurements will be used to calibrate computational fluid dynamics turbulence models and characterize the back-pressured flow of a scramjet isolator. This paper describes the test apparatus, including the optical access appendages; the physics of the LITA method; and estimates of LITA measurement uncertainty for measurements of the speed of sound and temperature.

  19. The Female Population Growth Projection Year 2021 in Trenggalek Regency by Leslie Matrix Model on the Birth Rate and Life Expectancy

    Directory of Open Access Journals (Sweden)

    Dewi Anggreini

    2017-10-01

    Full Text Available This research aims to determine the number of female residents in Trenggalek Regency in 2021 based on data on birth rate and life expectancy. The use of eigenvalues and eigenvectors aims to determine the dividing age distribution by Leslie matrix model. The eigenvectors are used to determine the number of female populations of each age interval, while the eigenvalues are used to determine population growth rates. The research method used is to determine the subject of research. The next stage is to collect research data, then analyze the data and last draw conclusions. The research data is obtained from BPS Kabupaten Trenggalek and BPS East Java Province that is data of woman population from year 2010-2015. The result of this research using Leslie matrix model for female population in Trenggalek Regency that is discrete model. The discrete model is divided into fourteen age intervals constructed using the birthrate and life expectancy. The conclusions of the study showed that the number of female population in Trenggalek Regency tended to increase with positive eigen value greater than one. In other words, the growth rate of female population in Trenggalek Regency tends to be positive. The success of Leslie's matrix model is the application of case studies in predicting the number of female populations in Trenggalek District by 2021 using the MAPLE 16 Program.

  20. What tomorrow brings? examining a model of antecedents of career expectations / Como será amanhã? examinando um modelo de antecedentes de expectativas de carreira

    Directory of Open Access Journals (Sweden)

    Vinicius Carvalho de Vasconcellos

    2016-10-01

    Full Text Available Purpose: Analyze if the perceptions about policies and practices on human resources management (HRM, well-being at work and expectations of organizational future act as antecedents of career expectations in the organization. Originality/gap/relevance/implications: The question “What will my future be in this organization?” is a relevant part of working life. Thus, it is important to assess which variables influence future career expectations. Based on theoretical contributions and previous surveys about career, well-being and HRM, the model tested coordinates variables that are analyzed in isolate by literature. Key methodological aspects: In this quantitative survey, 305 professionals from a government agency completed an e-questionnaire with scales validated in Brazil. Data were analyzed through structural equations models. Summary of key results: The effects of well-being at work and expected future in the organization on the career expectations were positive and moderate, in the first case, and strong in the second case. The effect of perceptions of HR policies and practices on career expectations was completely mediated by well-being at work and expectations of organizational future. Key considerations/conclusions: Results support the relations theoretically conceived or found in previous qualitative surveys. In practical terms, data suggest that improving HR policies and practices can increase well-being at work and expectations of organizational future and, finally, foster positive career expectations in the organization. Considering that the research was limited to one organization, future investigations should analyze the model in other organizations. Objetivo: avaliar se percepções de políticas/práticas de recursos humanos (RH, bem-estar no trabalho e expectativas de futuro organizacional atuam como antecedentes de expectativas de carreira na organização. Originalidade/Lacuna/Relevância/Implicações: a questão “Como ser

  1. Evaluation of the Users’ Continuous Intention to Use PACS Based on the Expectation Confirmation Model in Teaching Hospitals of Shiraz University of Medical Sciences

    Directory of Open Access Journals (Sweden)

    Mohtaram Nematolahi

    2017-01-01

    Full Text Available Introduction: Users’ behavioral intention to use the Picture Archiving and Communication System (PACS is important in the systems’ success and is an indicator of the users’ satisfaction with commitment and dependence on information systems. The present study aimed to evaluate the users’ continuous intention to use PACS based on the expectation confirmation model in educational hospitals of Shiraz University of Medical Sciences. Method: This cross-sectional study was conducted in Nemazee and Shahid Faghihi hospitals, Shiraz, Iran in 2014. The subjects were 50 general practitioners, residents and specialists selected through stratified random sampling. The study data were collected using a researcher-made questionnaire. The content validity of the questionnaire items was confirmed by five experts in health information management. To evaluate the accuracy of relationships among the measurement models, reliability criteria, including Cronbach’s alpha and composite reliability, convergent and divergent validity were used which showed acceptable reliability and validity. The data were entered into Smart PLS software, version 3.1.9 and analyzed through Structural Equation Modeling (SEM by using Partial Least Squares (PLS approach. Results: The results showed appropriate fitness of reliability indices (Cronbach’s alpha >0.7, composite reliability >0.7, loading >0.7, validity indices (AVE >0.5, structural model (redundancy =0.395, Q2CI=0.364, f2H5=0.524, R2CI=0.687, and the total model (GoF=0.518. Moreover, all the research hypotheses, except H1 (the relationship between expectation confirmation and perceived usefulness with T-value of 1.96. Conclusion: Expectation confirmation, perceived usefulness, and satisfaction were effective in continuous intention to use PACS. Thus, these factors should be considered by designers, developers, and managers while designing and implementing information systems to guarantee their success and improve the

  2. Comparison of Farm Structures, Success Factors, Obstacles, Clients’ Expectations and Policy Wishes of Urban Farming’s Main Business Models in North Rhine-Westphalia, Germany

    Directory of Open Access Journals (Sweden)

    Bernd Pölling

    2016-05-01

    Full Text Available Low-cost specialization, differentiation, and diversification are common business models of urban farms in developed countries. Similarities and differences between them as well as detailed insights into specific farm characteristics are widely absent in scientific discourses. This paper compares farm structures, success factors, obstacles, clients’ expectations, and policy wishes between specialized, differentiated, and diversified farms as well as diversifiers into agriculture. A standardized questionnaire was used for 21 personal in-depth farm interviews located in metropolitan areas of North Rhine-Westphalia, Germany. Being located in a metropolitan area is the most often named Unique Selling Proposition (USP. This is also mentioned as most important success factor followed by sociability and personal contact to clients, which both underpin the importance of direct producer-consumer linkages in urban settings. Additionally, it is assumed that a single food criterion is not sufficient to be successful, but several have to be merged to meet clients’ expectations. In terms of marketing, differentiated and diversified farmers prefer a multi-channel approach, while specialized farmers and diversifiers into agriculture focus mainly on one specific channel. While both specialized farmers and diversifiers into agriculture cultivate smaller areas of farmland, the latter one offers the greatest number of jobs including those outside agricultural production. The findings obtained are expected to support farms and agricultural advisory services in individual decision making of future business development strategies and increase knowledge of urban farming’s main business models.

  3. Discussing Landscape Compositional Scenarios Generated with Maximization of Non-Expected Utility Decision Models Based on Weighted Entropies

    Directory of Open Access Journals (Sweden)

    José Pinto Casquilho

    2017-02-01

    Full Text Available The search for hypothetical optimal solutions of landscape composition is a major issue in landscape planning and it can be outlined in a two-dimensional decision space involving economic value and landscape diversity, the latter being considered as a potential safeguard to the provision of services and externalities not accounted in the economic value. In this paper, we use decision models with different utility valuations combined with weighted entropies respectively incorporating rarity factors associated to Gini-Simpson and Shannon measures. A small example of this framework is provided and discussed for landscape compositional scenarios in the region of Nisa, Portugal. The optimal solutions relative to the different cases considered are assessed in the two-dimensional decision space using a benchmark indicator. The results indicate that the likely best combination is achieved by the solution using Shannon weighted entropy and a square root utility function, corresponding to a risk-averse behavior associated to the precautionary principle linked to safeguarding landscape diversity, anchoring for ecosystem services provision and other externalities. Further developments are suggested, mainly those relative to the hypothesis that the decision models here outlined could be used to revisit the stability-complexity debate in the field of ecological studies.

  4. Deriving the largest expected number of elementary particles in the standard model from the maximal compact subgroup H of the exceptional Lie group E7(-5)

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2008-01-01

    The maximal number of elementary particles which could be expected to be found within a modestly extended energy scale of the standard model was found using various methods to be N = 69. In particular using E-infinity theory the present Author found the exact transfinite expectation value to be =α-bar o /2≅69 where α-bar o =137.082039325 is the exact inverse fine structure constant. In the present work we show among other things how to derive the exact integer value 69 from the exceptional Lie symmetry groups hierarchy. It is found that the relevant number is given by dim H = 69 where H is the maximal compact subspace of E 7(-5) so that N = dim H = 69 while dim E 7 = 133

  5. Fitting Nonlinear Ordinary Differential Equation Models with Random Effects and Unknown Initial Conditions Using the Stochastic Approximation Expectation-Maximization (SAEM) Algorithm.

    Science.gov (United States)

    Chow, Sy-Miin; Lu, Zhaohua; Sherwood, Andrew; Zhu, Hongtu

    2016-03-01

    The past decade has evidenced the increased prevalence of irregularly spaced longitudinal data in social sciences. Clearly lacking, however, are modeling tools that allow researchers to fit dynamic models to irregularly spaced data, particularly data that show nonlinearity and heterogeneity in dynamical structures. We consider the issue of fitting multivariate nonlinear differential equation models with random effects and unknown initial conditions to irregularly spaced data. A stochastic approximation expectation-maximization algorithm is proposed and its performance is evaluated using a benchmark nonlinear dynamical systems model, namely, the Van der Pol oscillator equations. The empirical utility of the proposed technique is illustrated using a set of 24-h ambulatory cardiovascular data from 168 men and women. Pertinent methodological challenges and unresolved issues are discussed.

  6. SP-100 initial startup and restart control strategy

    Science.gov (United States)

    Halfen, Frank J.; Wong, Kwok K.; Switick, Dennis M.; Shukla, Jaikaran N.

    Startup control strategies for SP-100 are described. Revised control and operating strategies are discussed which have been developed and tested using the SP-100 dynamic simulation model Aries-GFS (Generic Flight System).

  7. Estimating oxygen needs for childhood pneumonia in developing country health systems: a new model for expecting the unexpected.

    Directory of Open Access Journals (Sweden)

    Beverly D Bradley

    Full Text Available Planning for the reliable and cost-effective supply of a health service commodity such as medical oxygen requires an understanding of the dynamic need or 'demand' for the commodity over time. In developing country health systems, however, collecting longitudinal clinical data for forecasting purposes is very difficult. Furthermore, approaches to estimating demand for supplies based on annual averages can underestimate demand some of the time by missing temporal variability.A discrete event simulation model was developed to estimate variable demand for a health service commodity using the important example of medical oxygen for childhood pneumonia. The model is based on five key factors affecting oxygen demand: annual pneumonia admission rate, hypoxaemia prevalence, degree of seasonality, treatment duration, and oxygen flow rate. These parameters were varied over a wide range of values to generate simulation results for different settings. Total oxygen volume, peak patient load, and hours spent above average-based demand estimates were computed for both low and high seasons.Oxygen demand estimates based on annual average values of demand factors can often severely underestimate actual demand. For scenarios with high hypoxaemia prevalence and degree of seasonality, demand can exceed average levels up to 68% of the time. Even for typical scenarios, demand may exceed three times the average level for several hours per day. Peak patient load is sensitive to hypoxaemia prevalence, whereas time spent at such peak loads is strongly influenced by degree of seasonality.A theoretical study is presented whereby a simulation approach to estimating oxygen demand is used to better capture temporal variability compared to standard average-based approaches. This approach provides better grounds for health service planning, including decision-making around technologies for oxygen delivery. Beyond oxygen, this approach is widely applicable to other areas of

  8. Analytical modeling of complete Nukiyama curves corresponding to expected low void fraction at high subcooling and flow rate

    International Nuclear Information System (INIS)

    Schroeder-Richter, D.

    1996-01-01

    On the basis of a new hypothesis of thermodynamic states (the superheated wall layer is not metastable but saturated at locally elevated pressure), an analytical estimation is presented of the whole boiling curve [except critical heat flux (CHF), but fixed at this point, known by experiments or correlation]. The curvature of the boiling curve (bubbly flow) is deduced from thermodynamics of irreversible processes. The wall temperature corresponding to departure from nucleate boiling is calculated from balances of momentum at the interfaces, based on the assumption that the speed of sound may be a limit for maximum evaporation mass flux and thereby heat flux, i.e., CHF. Heat flux during transition boiling is determined from balance of energy at the rewetting front. The Leidenfrost temperature, as well as wall temperature at CHF, can be calculated analytically without using empirical coefficients. Heat flux of bubbly flow and transition boiling can be matched at any empirical CHF point. All these results are determined from properties of state alone, i.e., the models can be verified for all fluids including water and liquid metals (so far at moderate heat fluxes). 52 refs., 11 figs., 2 tabs

  9. Macroeconomic Expectations of Households and Professional Forecasters

    OpenAIRE

    Christopher D Carroll

    2002-01-01

    Economists have long emphasized the importance of expectations in determining macroeconomic outcomes Yet there has been almost no recent effort to model actual empirical expectations data; instead macroeconomists usually simply assume expectations are rational This paper shows that while empirical household expectations are not rational in the usual sense expectational dynamics are well captured by a model in which households' views derive from news reports of the views of professional foreca...

  10. Comparison of Scalar Expectancy Theory (SET) and the Learning-to-Time (LeT) model in a successive temporal bisection task.

    Science.gov (United States)

    Arantes, Joana

    2008-06-01

    The present research tested the generality of the "context effect" previously reported in experiments using temporal double bisection tasks [e.g., Arantes, J., Machado, A. Context effects in a temporal discrimination task: Further tests of the Scalar Expectancy Theory and Learning-to-Time models. J. Exp. Anal. Behav., in press]. Pigeons learned two temporal discriminations in which all the stimuli appear successively: 1s (red) vs. 4s (green) and 4s (blue) vs. 16s (yellow). Then, two tests were conducted to compare predictions of two timing models, Scalar Expectancy Theory (SET) and the Learning-to-Time (LeT) model. In one test, two psychometric functions were obtained by presenting pigeons with intermediate signal durations (1-4s and 4-16s). Results were mixed. In the critical test, pigeons were exposed to signals ranging from 1 to 16s and followed by the green or the blue key. Whereas SET predicted that the relative response rate to each of these keys should be independent of the signal duration, LeT predicted that the relative response rate to the green key (compared with the blue key) should increase with the signal duration. Results were consistent with LeT's predictions, showing that the context effect is obtained even when subjects do not need to make a choice between two keys presented simultaneously.

  11. Mathematical modeling of fed-batch fermentation of Schizochytrium sp. FJU-512 growth and DHA production using a shift control strategy.

    Science.gov (United States)

    Zhang, Mingliang; Wu, Weibin; Guo, Xiaolei; Weichen, You; Qi, Feng; Jiang, Xianzhang; Huang, Jianzhong

    2018-03-01

    To obtain high-cell-density cultures of Schizochytrium sp. FJU-512 for DHA production, two stages of fermentation strategy were used and carbon/nitrogen ratio, DO and temperature were controlled at different levels. The final dry cell weight, total lipid production and DHA yield in 15 l bioreactor reached 103.9, 37.2 and 16.0 g/l, respectively. For the further study of microbial growth and DHA production dynamics, we established a set of kinetic models for the fed-batch production of DHA by Schizochytrium sp. FJU-512 in 15 and 100 l fermenters and a compensatory parameter n was integrated into the model in order to find the optimal mathematical equations. A modified Logistic model was proposed to fit the cell growth data and the following kinetic parameters were obtained: µ m  = 0.0525/h, X m  = 100 g/l and n  = 4.1717 for the 15 l bioreactor, as well as µ m  = 0.0382/h, X m  = 107.4371 g/l and n  = 10 for the 100 l bioreactor. The Luedeking-Piret equations were utilized to model DHA production, yielding values of α  = 0.0648 g/g and β  = 0.0014 g/g/h for the 15 l bioreactor, while the values of α and β obtained for the 100 l fermentation were 0.0209 g/g and 0.0030 g/g/h. The predicted results compared with experimental data showed that the established models had a good fitting precision and were able to exactly depict the dynamic features of the DHA production process.

  12. Dynamic model of a thin layer photobioreactor, used for the cultivation of the microalga Chlorella sp. and bacteria in wastewater of high organic load

    Directory of Open Access Journals (Sweden)

    Orlando Gines Alfaro-Vives

    2017-01-01

    Full Text Available A dynamic mathematical model is presented to describe the symbiotic growth of the microalgae Chlorella sp. and bacteria in a photobioreactor thin film used in the wastewater treatment of high organic load. A good correlation is shown by the experimental results, since the variations of the process parameters (pH, dissolved oxygen concentration, concentration of dissolved carbon dioxide and substrate concentration in the culture medium were compared with the experimental results and in 95 % of cases coincide with an error of + -3%. Furthermore, the influence of the operating parameters on the performance of algae obtained is evaluated, using the model, the total net productivity per unit area was obtained with a maximum error of + -2, 5 % with respect to the experimental values.

  13. Model Polikultur Udang Windu (Penaeus monodon Fab, Ikan Bandeng (Chanos-chanos Forskal dan Rumput Laut (Gracillaria Sp. Secara Tradisional

    Directory of Open Access Journals (Sweden)

    Murachman - -

    2012-05-01

    Full Text Available Abstrak Polikultur merupakan salah satu alternatif untuk mengatasi permasalahan air yang mengakibatkan penurunan produksi ikan di kolam. Penelitian ini bertujuan untuk mengetahui menyusun pola manajemen polikultur udang windu (Penaeus monodon Fab., ikan bandeng (Chanos-chanos Forskal dan rumput laut (Gracillaria sp.. Penelitian dilakukan dengan metode studi kasus di Dusun Tanjung Sari, Desa Kupang, Kecamatan Jabon, Kabupaten Sidoarjo. Sampel penelitian diambil pada 18 lokasi polikultur dari tiga komoditas tersebut (udang windu, ikan bandeng dan rumput laut dan 20 lokasi polikultur dari dua komunitas (udang windu dan ikan bandeng. Variabel yang dipergunakan pada penelitian ini adalah Variabel penelitian meliputi lingkungan makro tambak, karakteristik pembudidaya, cara pengelolaan tambak dan perlakuan–perlakuan yang diberikan, padat tebar, kualitas air, kesuburan air, produksi tambak, keuntungan pembudidaya polikultur dan model budidaya polikultur tiga komoditas. Model budidaya polikultur terdiri dari enam komponen yaitu penentuan lokasi tambak, persiapan tambak, pemeliharaan, panen, kelembagaan sosial dan kelembagaan ekonomi. Masing-masing komponne tersebut saling berhubungan. Berdasarkan hasil penelitian diketahui bahwa terdapat tiga faktor yang mendukung penentuan lokasi kolam, yaitu jenis tanah di atas kolam, sumber air tawar, sumber air laut, dan keberadaan hutan mangrove. Kualitas dan kesuburan air cukup baik dan berada pada kisaran standard kualitas air untuk tambak. Tidak terdapat perbedaan yang signifikan antara padat tebar untuk udang windu dan ikan bandeng pada tipe polikultur tiga komoditas dan polikultur dua komoditas. Padat tebar rumput laut pada polikultur tiga komoditas adalah 975 kgha-1. Keberadaan rumput laut pada polikultur tiga komoditas dapat meningkatkan kualitas air menjadi lebih baik dibandingkan pada polikultur dua komoditas. Kandungan oksigen terlarut pada tambak adalah 165 mgl-1, tingkat kejernihan air 50.875 cm, NH3 0

  14. Choices and changes: Eccles' Expectancy-Value model and upper-secondary school students' longitudinal reflections about their choice of a STEM education

    Science.gov (United States)

    Lykkegaard, Eva; Ulriksen, Lars

    2016-03-01

    During the past 30 years, Eccles' comprehensive social-psychological Expectancy-Value Model of Motivated Behavioural Choices (EV-MBC model) has been proven suitable for studying educational choices related to Science, Technology, Engineering and/or Mathematics (STEM). The reflections of 15 students in their last year in upper-secondary school concerning their choice of tertiary education were examined using quantitative EV-MBC surveys and repeated qualitative interviews. This article presents the analyses of three cases in detail. The analytical focus was whether the factors indicated in the EV-MBC model could be used to detect significant changes in the students' educational choice processes. An important finding was that the quantitative EV-MBC surveys and the qualitative interviews gave quite different results concerning the students' considerations about the choice of tertiary education, and that significant changes in the students' reflections were not captured by the factors of the EV-MBC model. This questions the validity of the EV-MBC surveys. Moreover, the quantitative factors from the EV-MBC model did not sufficiently explain students' dynamical educational choice processes where students in parallel considered several different potential educational trajectories. We therefore call for further studies of the EV-MBC model's use in describing longitudinal choice processes and especially in investigating significant changes.

  15. Expecting the unexpected

    DEFF Research Database (Denmark)

    Mcneill, Ilona M.; Dunlop, Patrick D.; Heath, Jonathan B.

    2013-01-01

    People who live in wildfire-prone communities tend to form their own hazard-related expectations, which may influence their willingness to prepare for a fire. Past research has already identified two important expectancy-based factors associated with people's intentions to prepare for a natural......) and measured actual rather than intended preparedness. In addition, we tested the relation between preparedness and two additional threat-related expectations: the expectation that one can rely on an official warning and the expectation of encountering obstacles (e.g., the loss of utilities) during a fire...

  16. Treatment cost and life expectancy of diffuse large B-cell lymphoma (DLBCL): a discrete event simulation model on a UK population-based observational cohort.

    Science.gov (United States)

    Wang, Han-I; Smith, Alexandra; Aas, Eline; Roman, Eve; Crouch, Simon; Burton, Cathy; Patmore, Russell

    2017-03-01

    Diffuse large B-cell lymphoma (DLBCL) is the commonest non-Hodgkin lymphoma. Previous studies examining the cost of treating DLBCL have generally focused on a specific first-line therapy alone; meaning that their findings can neither be extrapolated to the general patient population nor to other points along the treatment pathway. Based on empirical data from a representative population-based patient cohort, the objective of this study was to develop a simulation model that could predict costs and life expectancy of treating DLBCL. All patients newly diagnosed with DLBCL in the UK's population-based Haematological Malignancy Research Network ( www.hmrn.org ) in 2007 were followed until 2013 (n = 271). Mapped treatment pathways, alongside cost information derived from the National Tariff 2013/14, were incorporated into a patient-level simulation model in order to reflect the heterogeneities of patient characteristics and treatment options. The NHS and social services perspective was adopted, and all outcomes were discounted at 3.5 % per annum. Overall, the expected total medical costs were £22,122 for those treated with curative intent, and £2930 for those managed palliatively. For curative chemotherapy, the predicted medical costs were £14,966, £23,449 and £7376 for first-, second- and third-line treatments, respectively. The estimated annual cost for treating DLBCL across the UK was around £88-92 million. This is the first cost modelling study using empirical data to provide 'real world' evidence throughout the DLBCL treatment pathway. Future application of the model could include evaluation of new technologies/treatments to support healthcare decision makers, especially in the era of personalised medicine.

  17. Photosynthetic Versatility in the Genome of Geitlerinema sp. PCC 9228 (Formerly Oscillatoria limnetica 'Solar Lake'), a Model Anoxygenic Photosynthetic Cyanobacterium.

    Science.gov (United States)

    Grim, Sharon L; Dick, Gregory J

    2016-01-01

    Anoxygenic cyanobacteria that use sulfide as the electron donor for photosynthesis are a potentially influential but poorly constrained force on Earth's biogeochemistry. Their versatile metabolism may have boosted primary production and nitrogen cycling in euxinic coastal margins in the Proterozoic. In addition, they represent a biological mechanism for limiting the accumulation of atmospheric oxygen, especially before the Great Oxidation Event and in the low-oxygen conditions of the Proterozoic. In this study, we describe the draft genome sequence of Geitlerinema sp. PCC 9228, formerly Oscillatoria limnetica 'Solar Lake', a mat-forming diazotrophic cyanobacterium that can switch between oxygenic photosynthesis and sulfide-based anoxygenic photosynthesis (AP). Geitlerinema possesses three variants of psbA , which encodes protein D1, a core component of the photosystem II reaction center. Phylogenetic analyses indicate that one variant is closely affiliated with cyanobacterial psbA genes that code for a D1 protein used for oxygen-sensitive processes. Another version is phylogenetically similar to cyanobacterial psbA genes that encode D1 proteins used under microaerobic conditions, and the third variant may be cued to high light and/or elevated oxygen concentrations. Geitlerinema has the canonical gene for sulfide quinone reductase (SQR) used in cyanobacterial AP and a putative transcriptional regulatory gene in the same operon. Another operon with a second, distinct sqr and regulatory gene is present, and is phylogenetically related to sqr genes used for high sulfide concentrations. The genome has a comprehensive nif gene suite for nitrogen fixation, supporting previous observations of nitrogenase activity. Geitlerinema possesses a bidirectional hydrogenase rather than the uptake hydrogenase typically used by cyanobacteria in diazotrophy. Overall, the genome sequence of Geitlerinema sp. PCC 9228 highlights potential cyanobacterial strategies to cope with fluctuating

  18. Response Expectancy and the Placebo Effect.

    Science.gov (United States)

    Kirsch, Irving

    2018-01-01

    In this chapter, I review basic tenets of response expectancy theory (Kirsch, 1985), beginning with the important distinction between response expectancies and stimulus expectancies. Although both can affect experience, the effects of response expectancies are stronger and more resistant to extinction than those of stimulus expectancies. Further, response expectancies are especially important to understanding placebo effects. The response expectancy framework is consistent with and has been amplified by the Bayesian model of predictive coding. Clinical implications of these phenomena are exemplified. © 2018 Elsevier Inc. All rights reserved.

  19. SP (4,R) symmetry in light nuclei

    International Nuclear Information System (INIS)

    Peterson, D.R.

    1979-01-01

    A classification of nuclear states according to the noncompact sympletic Lie algebras sp(2n,R), n = 1, 2, 3, is investigated. Such a classification has recently been shown to be physically meaningful. This classification scheme is the appropriate generalization fo Elliott's SU 3 model of rotational states in deformed light nuclei to include core excitations. A restricted classification according to the Lie algebra, sp(4,R), is motivated. Truncation of the model space to a single sp(4,R) irreducible representation allows the inclusion of states possessing very high excitation energy. An sp(4,R) model study is performed on S = T = 0 positive-parity rotational bands in the deformed light nuclei 16 O and 24 Mg. States are included in the model space that possess up to 10h ω in excitation energy. Results for the B(E2) transition rates compare favorable with experiment, without resort to effective charges

  20. Determining health expectancies

    National Research Council Canada - National Science Library

    Robine, Jean-Marie

    2003-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Jean-Marie Robine 9 1 Increase in Life Expectancy and Concentration of Ages at Death . . . . France Mesle´ and Jacques Vallin 13 2 Compression of Morbidity...

  1. Interest rate rules with heterogeneous expectations

    NARCIS (Netherlands)

    Anufriev, M.; Assenza, T.; Hommes, C.; Massaro, D.

    2011-01-01

    The recent macroeconomic literature stresses the importance of managing heterogeneous expectations in the formulation of monetary policy. We use a simple frictionless DSGE model to investigate inflation dynamics under alternative interest rate rules when agents have heterogeneous expectations and

  2. A Mathematical Model of Neutral Lipid Content in terms of Initial Nitrogen Concentration and Validation in Coelastrum sp. HA-1 and Application in Chlorella sorokiniana

    Directory of Open Access Journals (Sweden)

    Zhenhua Yang

    2017-01-01

    Full Text Available Microalgae are considered to be a potential major biomass feedstock for biofuel due to their high lipid content. However, no correlation equations as a function of initial nitrogen concentration for lipid accumulation have been developed for simplicity to predict lipid production and optimize the lipid production process. In this study, a lipid accumulation model was developed with simple parameters based on the assumption protein synthesis shift to lipid synthesis by a linear function of nitrogen quota. The model predictions fitted well for the growth, lipid content, and nitrogen consumption of Coelastrum sp. HA-1 under various initial nitrogen concentrations. Then the model was applied successfully in Chlorella sorokiniana to predict the lipid content with different light intensities. The quantitative relationship between initial nitrogen concentrations and the final lipid content with sensitivity analysis of the model were also discussed. Based on the model results, the conversion efficiency from protein synthesis to lipid synthesis is higher and higher in microalgae metabolism process as nitrogen decreases; however, the carbohydrate composition content remains basically unchanged neither in HA-1 nor in C. sorokiniana.

  3. A Mathematical Model of Neutral Lipid Content in terms of Initial Nitrogen Concentration and Validation in Coelastrum sp. HA-1 and Application in Chlorella sorokiniana

    Science.gov (United States)

    Zhao, Yue; Liu, Zhiyong; Liu, Chenfeng; Hu, Zhipeng

    2017-01-01

    Microalgae are considered to be a potential major biomass feedstock for biofuel due to their high lipid content. However, no correlation equations as a function of initial nitrogen concentration for lipid accumulation have been developed for simplicity to predict lipid production and optimize the lipid production process. In this study, a lipid accumulation model was developed with simple parameters based on the assumption protein synthesis shift to lipid synthesis by a linear function of nitrogen quota. The model predictions fitted well for the growth, lipid content, and nitrogen consumption of Coelastrum sp. HA-1 under various initial nitrogen concentrations. Then the model was applied successfully in Chlorella sorokiniana to predict the lipid content with different light intensities. The quantitative relationship between initial nitrogen concentrations and the final lipid content with sensitivity analysis of the model were also discussed. Based on the model results, the conversion efficiency from protein synthesis to lipid synthesis is higher and higher in microalgae metabolism process as nitrogen decreases; however, the carbohydrate composition content remains basically unchanged neither in HA-1 nor in C. sorokiniana. PMID:28194424

  4. Clinical evaluation of iterative reconstruction (ordered-subset expectation maximization) in dynamic positron emission tomography: quantitative effects on kinetic modeling with N-13 ammonia in healthy subjects

    DEFF Research Database (Denmark)

    Hove, Jens D; Rasmussen, Rune; Freiberg, Jacob

    2008-01-01

    BACKGROUND: The purpose of this study was to investigate the quantitative properties of ordered-subset expectation maximization (OSEM) on kinetic modeling with nitrogen 13 ammonia compared with filtered backprojection (FBP) in healthy subjects. METHODS AND RESULTS: Cardiac N-13 ammonia positron...... emission tomography (PET) studies from 20 normal volunteers at rest and during dipyridamole stimulation were analyzed. Image data were reconstructed with either FBP or OSEM. FBP- and OSEM-derived input functions and tissue curves were compared together with the myocardial blood flow and spillover values...... and OSEM flow values were observed with a flow underestimation of 45% (rest/dipyridamole) in the septum and of 5% (rest) and 15% (dipyridamole) in the lateral myocardial wall. CONCLUSIONS: OSEM reconstruction of myocardial perfusion images with N-13 ammonia and PET produces high-quality images for visual...

  5. Performance appraisal of expectations

    Directory of Open Access Journals (Sweden)

    Russkikh G.A.

    2016-11-01

    Full Text Available this article provides basic concepts for teachers to estimate and reach planned students’ expectations, describes functions and elements of expectations; nature of external and internal estimate, technology to estimate the results, gives recommendations how to create diagnostic assignments.

  6. Spiking the expectancy profiles

    DEFF Research Database (Denmark)

    Hansen, Niels Chr.; Loui, Psyche; Vuust, Peter

    Melodic expectations are generated with different degrees of certainty. Given distributions of expectedness ratings for multiple continuations of each context, as obtained with the probe-tone paradigm, this certainty can be quantified in terms of Shannon entropy. Because expectations arise from s...

  7. Homology modeling and docking studies of a Δ9-fatty acid desaturase from a Cold-tolerant Pseudomonas sp. AMS8

    Directory of Open Access Journals (Sweden)

    Lawal Garba

    2018-03-01

    Full Text Available Membrane-bound fatty acid desaturases perform oxygenated desaturation reactions to insert double bonds within fatty acyl chains in regioselective and stereoselective manners. The Δ9-fatty acid desaturase strictly creates the first double bond between C9 and 10 positions of most saturated substrates. As the three-dimensional structures of the bacterial membrane fatty acid desaturases are not available, relevant information about the enzymes are derived from their amino acid sequences, site-directed mutagenesis and domain swapping in similar membrane-bound desaturases. The cold-tolerant Pseudomonas sp. AMS8 was found to produce high amount of monounsaturated fatty acids at low temperature. Subsequently, an active Δ9-fatty acid desaturase was isolated and functionally expressed in Escherichia coli. In this paper we report homology modeling and docking studies of a Δ9-fatty acid desaturase from a Cold-tolerant Pseudomonas sp. AMS8 for the first time to the best of our knowledge. Three dimensional structure of the enzyme was built using MODELLER version 9.18 using a suitable template. The protein model contained the three conserved-histidine residues typical for all membrane-bound desaturase catalytic activity. The structure was subjected to energy minimization and checked for correctness using Ramachandran plots and ERRAT, which showed a good quality model of 91.6 and 65.0%, respectively. The protein model was used to preform MD simulation and docking of palmitic acid using CHARMM36 force field in GROMACS Version 5 and Autodock tool Version 4.2, respectively. The docking simulation with the lowest binding energy, −6.8 kcal/mol had a number of residues in close contact with the docked palmitic acid namely, Ile26, Tyr95, Val179, Gly180, Pro64, Glu203, His34, His206, His71, Arg182, Thr85, Lys98 and His177. Interestingly, among the binding residues are His34, His71 and His206 from the first, second, and third conserved histidine motif, respectively

  8. Investigation of Pumped Storage Hydropower Power-Off Transient Process Using 3D Numerical Simulation Based on SP-VOF Hybrid Model

    Directory of Open Access Journals (Sweden)

    Daqing Zhou

    2018-04-01

    Full Text Available The transient characteristic of the power-off process is investigated due to its close relation to hydraulic facilities’ safety in a pumped storage hydropower (PSH. In this paper, power-off transient characteristics of a PSH station in pump mode was studied using a three-dimensional (3D unsteady numerical method based on a single-phase and volume of fluid (SP-VOF coupled model. The computational domain covered the entire flow system, including reservoirs, diversion tunnel, surge tank, pump-turbine unit, and tailrace tunnel. The fast changing flow fields and dynamic characteristic parameters, such as unit flow rate, runner rotate speed, pumping lift, and static pressure at measuring points were simulated, and agreed well with experimental results. During the power-off transient process, the PSH station underwent pump mode, braking mode, and turbine mode, with the dynamic characteristics and inner flow configurations changing significantly. Intense pressure fluctuation occurred in the region between the runner and guide vanes, and its frequency and amplitude were closely related to the runner’s rotation speed and pressure gradient, respectively. While the reversed flow rate of the PSH unit reached maximum, some parameters, such as static pressure, torque, and pumping lift would suddenly jump significantly, due to the water hammer effect. The moment these marked jumps occurred was commonly considered as the most dangerous moment during the power-off transient process, due to the blade passages being clogged by vortexes, and chaos pressure distribution on the blade surfaces. The results of this study confirm that 3D SP-VOF hybrid simulation is an effective method to reveal the hydraulic mechanism of the PSH transient process.

  9. ExaSP2

    Energy Technology Data Exchange (ETDEWEB)

    2017-09-08

    ExaSP2 is a reference implementation of typical linear algebra algorithms and workloads for a quantum molecular dynamics (QMD) electronic structure code. The algorithm is based on a recursive second-order Fermi-Operator expansion method (SP2) and is tailored for density functional based tight-binding calculations of material systems.

  10. Expected utility with lower probabilities

    DEFF Research Database (Denmark)

    Hendon, Ebbe; Jacobsen, Hans Jørgen; Sloth, Birgitte

    1994-01-01

    An uncertain and not just risky situation may be modeled using so-called belief functions assigning lower probabilities to subsets of outcomes. In this article we extend the von Neumann-Morgenstern expected utility theory from probability measures to belief functions. We use this theory...

  11. Life expectancy and education

    DEFF Research Database (Denmark)

    Hansen, Casper Worm; Strulik, Holger

    2017-01-01

    , we find that US states with higher mortality rates from cardiovascular disease prior to the 1970s experienced greater increases in adult life expectancy and higher education enrollment. Our estimates suggest that a one-standard deviation higher treatment intensity is associated with an increase...... in adult life expectancy of 0.37 years and 0.07–0.15 more years of higher education....

  12. Expected Classification Accuracy

    Directory of Open Access Journals (Sweden)

    Lawrence M. Rudner

    2005-08-01

    Full Text Available Every time we make a classification based on a test score, we should expect some number..of misclassifications. Some examinees whose true ability is within a score range will have..observed scores outside of that range. A procedure for providing a classification table of..true and expected scores is developed for polytomously scored items under item response..theory and applied to state assessment data. A simplified procedure for estimating the..table entries is also presented.

  13. Expected years ever married

    Directory of Open Access Journals (Sweden)

    Ryohei Mogi

    2018-04-01

    Full Text Available Background: In the second half of the 20th century, remarkable marriage changes were seen: a great proportion of never married population, high average age at first marriage, and large variance in first marriage timing. Although it is theoretically possible to separate these three elements, disentangling them analytically remains a challenge. Objective: This study's goal is to answer the following questions: Which of the three effects, nonmarriage, delayed marriage, or expansion, has the most impact on nuptiality changes? How does the most influential factor differ by time periods, birth cohorts, and countries? Methods: To quantify nuptiality changes over time, we define the measure 'expected years ever married' (EYEM. We illustrate the use of EYEM, looking at time trends in 15 countries (six countries for cohort analysis and decompose these trends into three components: scale (the changes in the proportion of never married - nonmarriage, location (the changes in timing of first marriage - delayed marriage, and variance (the changes in the standard deviation of first marriage age - expansion. We used population counts by sex, age, and marital status from national statistical offices and the United Nations database. Results: Results show that delayed marriage is the most influential factor on period EYEM's changes, while nonmarriage has recently begun to contribute to the change in North and West Europe and Canada. Period and cohort analysis complement each other. Conclusions: This study introduces a new index of nuptiality and decomposes its change into the contribution of three components: scale, location, and variance. The decomposition steps presented here offer an open possibility for more elaborate parametric marriage models.

  14. Expectancies as a Determinant of Interference Phenomena

    Science.gov (United States)

    Hasher, Lynn; Greenberg, Michael

    1977-01-01

    One version, by Lockhart, Craik, and Jacoby, of a levels-of-processing model of memory asserts the importance of the role of expectancies about forthcoming information in determining the elaborateness of a memory trace. Confirmed expectancies result in less-elaborated memory traces; disconfirmed expectancies result in elaborate memory traces.…

  15. Heterogeneous inflation expectations, learning, and market outcomes

    OpenAIRE

    Madeira, Carlos; Zafar, Basit

    2012-01-01

    Using the panel component of the Michigan Survey of Consumers, we show that individuals, in particular women and ethnic minorities, are highly heterogeneous in their expectations of inflation. We estimate a model of inflation expectations based on learning from experience that also allows for heterogeneity in both private information and updating. Our model vastly outperforms existing models of inflation expectations in explaining the heterogeneity in the data. We find that women, ethnic mino...

  16. Expectancy-Value Theory of Achievement Motivation.

    Science.gov (United States)

    Wigfield; Eccles

    2000-01-01

    We discuss the expectancy-value theory of motivation, focusing on an expectancy-value model developed and researched by Eccles, Wigfield, and their colleagues. Definitions of crucial constructs in the model, including ability beliefs, expectancies for success, and the components of subjective task values, are provided. These definitions are compared to those of related constructs, including self-efficacy, intrinsic and extrinsic motivation, and interest. Research is reviewed dealing with two issues: (1) change in children's and adolescents' ability beliefs, expectancies for success, and subjective values, and (2) relations of children's and adolescents' ability-expectancy beliefs and subjective task values to their performance and choice of activities. Copyright 2000 Academic Press.

  17. Modeling of the overwintering distribution of Puccinia striiformis f. sp. tritici based on meteorological data from 2001 to 2012 in China

    Directory of Open Access Journals (Sweden)

    Xiaojing WANG,Zhanhong MA,Yuying JIANG,Shouding SHI,Wancai LIU,Juan ZENG,Zhiwei ZHAO,Haiguang WANG

    2014-09-01

    Full Text Available Wheat stripe rust caused by Puccinia striiformis f. sp. tritici occurs widely in China and seriously affects wheat production. Global warming could profoundly impact the incidence and prevalence of low-temperature diseases such as stripe rust. Studies on the effects of temperature on the distribution of overwintering stripe rust could help us understand the incidence and prevalence of the disease and could also provide support for monitoring, forecasting and developing control strategies. An exponential model and a spherical model of the ordinary Kriging method in the ArcGIS platform were used to predict the overwintering regions of stripe rust based on the probability that the average temperature of the coldest month from December to February was higher than -6 or -7ºC from 2001 to 2012. The results showed that the areas with a probability between 70% and 90% were transition regions for the overwintering of stripe rust. Based on annual mean temperature of the coldest month from December to February for 2001 to 2012, overwintering distribution of stripe rust was likewise evaluated. The boundary for overwintering of stripe rust was consistent with the areas where the probability was predicted to be 70% to 90% for the overwintering distribution of stripe rust, but the boundary was shifted northward toward Beijing in North China. Some areas in Xinjiang, including Akto, Pishan, Hotan and Yutian, were also predicted to be suitable for the overwintering of stripe rust.

  18. Fluence dependent changes of erosion yields and surface morphology of the iron-tungsten model system: SDTrimSP-2D simulation studies

    Directory of Open Access Journals (Sweden)

    U. von Toussaint

    2017-08-01

    Full Text Available The effect of different sample structures of an iron-tungsten model system (as a surrogate for reduced activation ferritic martensitic steels like EUROFER on the development of surface morphologies, tungsten surface enrichment and sputter yields under low-energy monoenergetic perpendicular 200 eV deuterium bombardment has been studied with SDTrimSP-2d simulations. Previous modeling studies considering diffusive effects also could reasonably reproduce and explain the experimental results for a large set of experimental parameters like temperature, flux and sample concentration. However, for settings with negligible Fe-W-interdiffusion the fluence needed for steady-state conditions differed between the experiments and the simulations. Thus, the main focus of the present study is directed towards the elucidation of this fluence mismatch. Comparison of one and two-dimensional simulation results reveal a strong dependency of the tungsten enrichment on the sample homogeneity and a significantly delayed reduction of the erosion yield due to a pronounced formation of surface structures from initially flat sample surfaces.

  19. A Mathematical Model for Simulating Remediation of Groundwater Contaminated by Heavy Metals using Bio-Carriers with Dead Baccilus sp. B1 and Polysulfone

    Science.gov (United States)

    Seo, H.; Wang, S.; Lee, M.

    2010-12-01

    The remediation of groundwater contaminated by heavy metals, organic contaminants, etc. using various types of bio-carriers has been widely studied as a novel technology in the literature. In this study, a series of batch experiments were conducted to investigated the fundamental characteristics in the removal process using bio-carriers (beads) with dead Bacillus sp. B1 and polysulfone. Through equilibrium and kinetic sorption experiments, sorption efficiencies for lead and copper under various conditions such as pH, temperature, contaminant concentration, etc. were examined and sorption parameters including maximum sorption capacities were obtained for model applications. Experimental data showed that equilibrium sorption patterns for Pb2+and Cu2+on bio-carrier beads follows Langmuir sorption isotherm and that the sorption dynamics can be described with a pseudo-second-order kinetics. One dimensional advective-dispersive-reactive transport model was also developed for simulating and analyzing the remediation processes. The HSDM (homogeneous surface diffusion model) were incorporated in the model to take into account the mass transfer and sorption mechanisms around/inside the bio-carrier beads. Applying the proposed model, numerical column experiments were carried out and the simulation results reasonably described temporal and spatial distribution of Pb2+and Cu2+in a fixed-bed flow-through sorption column. Experimental and numerical results showed that the main mechanism of the bio-carrier to remove heavy metals is the sorption on/inside of the bio-carriers and the bio-carriers can function as excellent biosorbents for the removal of heavy metal ions from groundwater.

  20. Política monetaria en el modelo con expectativas, curva de Phillips: práctica de ordenador Política monetària en el model amb expectatives, corba de Philipps: pràctica d'ordinador Monetary Policy in the Expectations Model, Phillips Curve: A Computer Practice

    Directory of Open Access Journals (Sweden)

    Jana Hromcová

    2009-12-01

    Full Text Available Recomendamos un ejercicio numérico que permite a los estudiantes observar la dinámica de un simple modelo, compuesto por la curva de Phillips, ley de Okun y demanda agregada, ante variaciones en la política monetaria. El ejercicio tiene como objetivo enseñar a los estudiantes la importancia de la manera en la que se forman las expectativas y la (nocredibilidad del banco central para el cumplimiento de los objetivos de la política monetaria.Monetary Policy in the Expectations Model, Phillips Curve: A Computer Practice

  1. Sex and life expectancy.

    Science.gov (United States)

    Seifarth, Joshua E; McGowan, Cheri L; Milne, Kevin J

    2012-12-01

    A sexual dimorphism in human life expectancy has existed in almost every country for as long as records have been kept. Although human life expectancy has increased each year, females still live longer, on average, than males. Undoubtedly, the reasons for the sex gap in life expectancy are multifaceted, and it has been discussed from both sociological and biological perspectives. However, even if biological factors make up only a small percentage of the determinants of the sex difference in this phenomenon, parity in average life expectancy should not be anticipated. The aim of this review is to highlight biological mechanisms that may underlie the sexual dimorphism in life expectancy. Using PubMed, ISI Web of Knowledge, and Google Scholar, as well as cited and citing reference histories of articles through August 2012, English-language articles were identified, read, and synthesized into categories that could account for biological sex differences in human life expectancy. The examination of biological mechanisms accounting for the female-based advantage in human life expectancy has been an active area of inquiry; however, it is still difficult to prove the relative importance of any 1 factor. Nonetheless, biological differences between the sexes do exist and include differences in genetic and physiological factors such as progressive skewing of X chromosome inactivation, telomere attrition, mitochondrial inheritance, hormonal and cellular responses to stress, immune function, and metabolic substrate handling among others. These factors may account for at least a part of the female advantage in human life expectancy. Despite noted gaps in sex equality, higher body fat percentages and lower physical activity levels globally at all ages, a sex-based gap in life expectancy exists in nearly every country for which data exist. There are several biological mechanisms that may contribute to explaining why females live longer than men on average, but the complexity of the

  2. Forecasting Spanish natural life expectancy.

    Science.gov (United States)

    Guillen, Montserrat; Vidiella-i-Anguera, Antoni

    2005-10-01

    Knowledge of trends in life expectancy is of major importance for policy planning. It is also a key indicator for assessing future development of life insurance products, substantiality of existing retirement schemes, and long-term care for the elderly. This article examines the feasibility of decomposing age-gender-specific accidental and natural mortality rates. We study this decomposition by using the Lee and Carter model. In particular, we fit the Poisson log-bilinear version of this model proposed by Wilmoth and Brouhns et al. to historical (1975-1998) Spanish mortality rates. In addition, by using the model introduced by Wilmoth and Valkonen we analyze mortality-gender differentials for accidental and natural rates. We present aggregated life expectancy forecasts compared with those constructed using nondecomposed mortality rates.

  3. Coupled modeling of groundwater flow solute transport, chemical reactions and microbial processes in the 'SP' island

    Energy Technology Data Exchange (ETDEWEB)

    Samper, Javier; Molinero, Jorg; Changbing, Yang; Zhang, Guoxiang

    2003-12-01

    The Redox Zone Experiment was carried out at the Aespoe HRL in order to study the redox behavior and the hydrochemistry of an isolated vertical fracture zone disturbed by the excavation of an access tunnel. Overall results and interpretation of the Redox Zone Project were reported by /Banwart et al, 1995/. Later, /Banwart et al, 1999/ presented a summary of the hydrochemistry of the Redox Zone Experiment. Coupled groundwater flow and reactive transport models of this experiment were carried out by /Molinero, 2000/ who proposed a revised conceptual model for the hydrogeology of the Redox Zone Experiment which could explain simultaneously measured drawdown and salinity data. The numerical model was found useful to understand the natural system. Several conclusions were drawn about the redox conditions of recharge waters, cation exchange capacity of the fracture zone and the role of mineral phases such as pyrite, calcite, hematite and goethite. This model could reproduce the measured trends of dissolved species, except for bicarbonate and sulfate which are affected by microbially-mediated processes. In order to explore the role of microbial processes, a coupled numerical model has been constructed which accounts for water flow, reactive transport and microbial processes. The results of this model is presented in this report. This model accounts for groundwater flow and reactive transport in a manner similar to that of /Molinero, 2000/ and extends the preliminary microbial model of /Zhang, 2001/ by accounting for microbially-driven organic matter fermentation and organic matter oxidation. This updated microbial model considers simultaneously the fermentation of particulate organic matter by yeast and the oxidation of dissolved organic matter, a product of fermentation. Dissolved organic matter is produced by yeast and serves also as a substrate for iron-reducing bacteria. Model results reproduce the observed increase in bicarbonate and sulfate concentration, thus

  4. Further tests of the Scalar Expectancy Theory (SET) and the Learning-to-Time (LeT) model in a temporal bisection task.

    Science.gov (United States)

    Machado, Armando; Arantes, Joana

    2006-06-01

    To contrast two models of timing, Scalar Expectancy Theory (SET) and Learning to Time (LeT), pigeons were exposed to a double temporal bisection procedure. On half of the trials, they learned to choose a red key after a 1s signal and a green key after a 4s signal; on the other half of the trials, they learned to choose a blue key after a 4-s signal and a yellow key after a 16-s signal. This was Phase A of an ABA design. On Phase B, the pigeons were divided into two groups and exposed to a new bisection task in which the signals ranged from 1 to 16s and the choice keys were blue and green. One group was reinforced for choosing blue after 1-s signals and green after 16-s signals and the other group was reinforced for the opposite mapping (green after 1-s signals and blue after 16-s signals). Whereas SET predicted no differences between the groups, LeT predicted that the former group would learn the new discrimination faster than the latter group. The results were consistent with LeT. Finally, the pigeons returned to Phase A. Only LeT made specific predictions regarding the reacquisition of the four temporal discriminations. These predictions were only partly consistent with the results.

  5. Anomalous vacuum expectation values

    International Nuclear Information System (INIS)

    Suzuki, H.

    1986-01-01

    The anomalous vacuum expectation value is defined as the expectation value of a quantity that vanishes by means of the field equations. Although this value is expected to vanish in quantum systems, regularization in general produces a finite value of this quantity. Calculation of this anomalous vacuum expectation value can be carried out in the general framework of field theory. The result is derived by subtraction of divergences and by zeta-function regularization. Various anomalies are included in these anomalous vacuum expectation values. This method is useful for deriving not only the conformal, chiral, and gravitational anomalies but also the supercurrent anomaly. The supercurrent anomaly is obtained in the case of N = 1 supersymmetric Yang-Mills theory in four, six, and ten dimensions. The original form of the energy-momentum tensor and the supercurrent have anomalies in their conservation laws. But the modification of these quantities to be equivalent to the original one on-shell causes no anomaly in their conservation laws and gives rise to anomalous traces

  6. Examining the relationships between posttraumatic stress disorder symptoms, positive smoking outcome expectancies, and cigarette smoking in people with substance use disorders: a multiple mediator model.

    Science.gov (United States)

    Hruska, Bryce; Bernier, Jennifer; Kenner, Frank; Kenne, Deric R; Boros, Alec P; Richardson, Christopher J; Delahanty, Douglas L

    2014-01-01

    Cigarette smoking is highly prevalent in people with substance use disorders (SUDs) and is associated with significant physical health problems. Posttraumatic stress disorder (PTSD) is also highly associated with both SUDs and cigarette smoking and may serve as a barrier to smoking cessation efforts. In addition, people with PTSD are more likely to hold positive smoking outcome expectancies (i.e., beliefs that smoking cigarettes results in positive outcomes); these beliefs may contribute to cigarette smoking in people with SUDs experiencing PTSD symptoms. The present study examined the relationship between PTSD symptoms and typical daily cigarette smoking/cigarette dependence symptoms in a sample of 227 trauma-exposed current smokers with SUDs (59.9% male, 89.4% Caucasian) seeking detoxification treatment services. Additionally, the indirect effects of multiple types of positive smoking outcome expectancies on these relationships were examined. Participants completed questionnaires assessing PTSD symptoms, positive smoking outcome expectancies, cigarette consumption, and cigarette dependence symptoms. Results indicated that PTSD symptoms were not directly related to cigarette consumption or cigarette dependence symptoms. However, negative affect reduction outcome expectancies were shown to have a significant indirect effect between PTSD symptoms and cigarette consumption, while negative affect reduction, boredom reduction, and taste-sensorimotor manipulation outcome expectancies were all found to have significant indirect effects between PTSD symptoms and cigarette dependence symptoms. The indirect effect involving negative affect reduction outcome expectancies was statistically larger than that of taste sensorimotor manipulation outcome expectancies, while negative affect reduction and boredom reduction outcome expectancies were comparable in magnitude. These results suggest that expectancies that smoking can manage negative affective experiences are related to

  7. Performance expectation plan

    Energy Technology Data Exchange (ETDEWEB)

    Ray, P.E.

    1998-09-04

    This document outlines the significant accomplishments of fiscal year 1998 for the Tank Waste Remediation System (TWRS) Project Hanford Management Contract (PHMC) team. Opportunities for improvement to better meet some performance expectations have been identified. The PHMC has performed at an excellent level in administration of leadership, planning, and technical direction. The contractor has met and made notable improvement of attaining customer satisfaction in mission execution. This document includes the team`s recommendation that the PHMC TWRS Performance Expectation Plan evaluation rating for fiscal year 1998 be an Excellent.

  8. Analysis of Äspö Pillar Stability Experiment: Continuous thermo-mechanical model development and calibration

    Czech Academy of Sciences Publication Activity Database

    Blaheta, Radim; Byczanski, Petr; Čermák, M.; Hrtus, Rostislav; Kohut, Roman; Kolcun, Alexej; Malík, Josef; Sysala, Stanislav

    2013-01-01

    Roč. 5, č. 2 (2013), s. 124-135 ISSN 1674-7755 Institutional support: RVO:68145535 Keywords : in situ pillar stability experiment * model calibration by back analysis * continuous mechanics * damage of granite rocks * Finite element method (FEM) Subject RIV: BA - General Mathematics http://www.sciencedirect.com/science/article/pii/S1674775513000103

  9. Interaction of Acidithiobacillus ferrooxidans, Rhizobium phaseoli and Rhodotorula sp. in bioleaching process based on Lotka–Volterra model

    Directory of Open Access Journals (Sweden)

    Xuecheng Zheng

    2016-07-01

    Conclusion: The relationship among microorganisms during leaching could be described appropriately by Lotka–Volterra model between the initial and peak values. The relationship of A. ferrooxidans and R. phaseoli could be considered as mutualism, whereas, the relationship of A. ferrooxidans and R. phaseoli could be considered as commensalism.

  10. A Discrete-Time Model for Daily S&P500 Returns and Realized Variations: Jumps and Leverage Effects

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Kretschmer, Uta; Pigorsch, Christian

    We develop an empirically highly accurate discrete-time daily stochastic volatility model that explicitly distinguishes between the jump and continuoustime components of price movements using nonparametric realized variation and Bipower variation measures constructed from high-frequency intraday...... dependencies inherent in the high-frequency intraday data....

  11. Behavior, Expectations and Status

    Science.gov (United States)

    Webster, Jr, Murray; Rashotte, Lisa Slattery

    2010-01-01

    We predict effects of behavior patterns and status on performance expectations and group inequality using an integrated theory developed by Fisek, Berger and Norman (1991). We next test those predictions using new experimental techniques we developed to control behavior patterns as independent variables. In a 10-condition experiment, predictions…

  12. Life Expectancy in 2040

    DEFF Research Database (Denmark)

    Canudas-Romo, Vladimir; DuGoff, Eva H; Wu, Albert W.

    2016-01-01

    We use expert clinical and public health opinion to estimate likely changes in the prevention and treatment of important disease conditions and how they will affect future life expectancy. Focus groups were held including clinical and public health faculty with expertise in the six leading causes...

  13. Desulfotignum toluenicum sp. nov., a novel toluene-degrading, sulphate-reducing bacterium isolated from an oil-reservoir model column.

    Science.gov (United States)

    Ommedal, Hege; Torsvik, Terje

    2007-12-01

    A Gram-negative, sulphate-reducing bacterium (strain H3(T)) was isolated from an oil-reservoir model column. The new isolate was able to oxidize toluene coupled to hydrogen sulphide production. For growth, the optimum salt concentration was 1.5 % (w/v), the optimum pH was 7.2 and the optimum temperature was 34 degrees C. The cells were straight to slightly curved rods, 0.6-1.0 microm in diameter and 1.4-2.5 microm in length. The predominant fatty acids were C(16 : 0), C(16 : 1)omega7c and C(17 : 0) cyclo, and the cells also contained dimethylacetals. Cloning and sequencing of a 1505 bp long fragment of the 16S rRNA gene showed that strain H3(T) is a member of the Deltaproteobacteria and is related closely to Desulfotignum balticum DSM 7044(T). The G+C content of the DNA was 52.0 mol% and the DNA-DNA similarity to D. balticum DSM 7044(T) was 56.1 %. Based on differences in DNA sequence and the unique property of toluene degradation, it is proposed that strain H3(T) should be designated a member of a novel species within the genus Desulfotignum, for which the name Desulfotignum toluenicum sp. nov. is proposed. The type strain is H3(T) (=DSM 18732(T)=ATCC BAA-1460(T)).

  14. SynechoNET: integrated protein-protein interaction database of a model cyanobacterium Synechocystis sp. PCC 6803

    OpenAIRE

    Kim, Woo-Yeon; Kang, Sungsoo; Kim, Byoung-Chul; Oh, Jeehyun; Cho, Seongwoong; Bhak, Jong; Choi, Jong-Soon

    2008-01-01

    Background Cyanobacteria are model organisms for studying photosynthesis, carbon and nitrogen assimilation, evolution of plant plastids, and adaptability to environmental stresses. Despite many studies on cyanobacteria, there is no web-based database of their regulatory and signaling protein-protein interaction networks to date. Description We report a database and website SynechoNET that provides predicted protein-protein interactions. SynechoNET shows cyanobacterial domain-domain interactio...

  15. Solute transport in crystalline rocks at Äspö — II: Blind predictions, inverse modelling and lessons learnt from test STT1

    Science.gov (United States)

    Jakob, Andreas; Mazurek, Martin; Heer, Walter

    2003-03-01

    Based on the results from detailed structural and petrological characterisation and on up-scaled laboratory values for sorption and diffusion, blind predictions were made for the STT1 dipole tracer test performed in the Swedish Äspö Hard Rock Laboratory. The tracers used were nonsorbing, such as uranine and tritiated water, weakly sorbing 22Na +, 85Sr 2+, 47Ca 2+and more strongly sorbing 86Rb +, 133Ba 2+, 137Cs +. Our model consists of two parts: (1) a flow part based on a 2D-streamtube formalism accounting for the natural background flow field and with an underlying homogeneous and isotropic transmissivity field and (2) a transport part in terms of the dual porosity medium approach which is linked to the flow part by the flow porosity. The calibration of the model was done using the data from one single uranine breakthrough (PDT3). The study clearly showed that matrix diffusion into a highly porous material, fault gouge, had to be included in our model evidenced by the characteristic shape of the breakthrough curve and in line with geological observations. After the disclosure of the measurements, it turned out that, in spite of the simplicity of our model, the prediction for the nonsorbing and weakly sorbing tracers was fairly good. The blind prediction for the more strongly sorbing tracers was in general less accurate. The reason for the good predictions is deemed to be the result of the choice of a model structure strongly based on geological observation. The breakthrough curves were inversely modelled to determine in situ values for the transport parameters and to draw consequences on the model structure applied. For good fits, only one additional fracture family in contact with cataclasite had to be taken into account, but no new transport mechanisms had to be invoked. The in situ values for the effective diffusion coefficient for fault gouge are a factor of 2-15 larger than the laboratory data. For cataclasite, both data sets have values comparable to

  16. Chinese students' great expectations

    DEFF Research Database (Denmark)

    Thøgersen, Stig

    2013-01-01

    The article focuses on Chinese students' hopes and expectations before leaving to study abroad. The national political environment for their decision to go abroad is shaped by an official narrative of China's transition to a more creative and innovative economy. Students draw on this narrative to...... system, they think of themselves as having a role in the transformation of Chinese attitudes to education and parent-child relations....

  17. Expectations from the child

    Directory of Open Access Journals (Sweden)

    Erdal Atabek

    2018-05-01

    Full Text Available Transition from agricultural society to industry society, from industrial society to science society has taken place. In all these societies, expectations from children also vary. In the agricultural community, human labor is based on arm power. For this reason, expectation from children is to increase work power. Having more children is the basis for the expectations in this community to see that the boy is valuable because he has increased his work power. In the industrial society, the power of the arm changed its place with the machine power. The knowledgeable person is not a family grown-up but a foreman. Childhood was distinguished during this period. It has been investigated that the child has a separate development.  In the information society, communication and information has never been as fast as it is in this period.  The widespread use of the Internet, and the use of social networks such as Facebook and Twitter are in this period. In this society, families are panicked to prepare a future in their own heads for their children. Because the parents thought of their children, they decided about the child's life instead of the child making these decisions. This has had a negative impact on children's sense of autonomy and their ability to take responsibility. To change this, parents should train their children in auto control and develop children's impulse control skills. The children should be able to understand their emotions and make decisions by reasoning and reasoning.

  18. Acetylome analysis reveals the involvement of lysine acetylation in photosynthesis and carbon metabolism in the model cyanobacterium Synechocystis sp. PCC 6803.

    Science.gov (United States)

    Mo, Ran; Yang, Mingkun; Chen, Zhuo; Cheng, Zhongyi; Yi, Xingling; Li, Chongyang; He, Chenliu; Xiong, Qian; Chen, Hui; Wang, Qiang; Ge, Feng

    2015-02-06

    Cyanobacteria are the oldest known life form inhabiting Earth and the only prokaryotes capable of performing oxygenic photosynthesis. Synechocystis sp. PCC 6803 (Synechocystis) is a model cyanobacterium used extensively in research on photosynthesis and environmental adaptation. Posttranslational protein modification by lysine acetylation plays a critical regulatory role in both eukaryotes and prokaryotes; however, its extent and function in cyanobacteria remain unexplored. Herein, we performed a global acetylome analysis on Synechocystis through peptide prefractionation, antibody enrichment, and high accuracy LC-MS/MS analysis; identified 776 acetylation sites on 513 acetylated proteins; and functionally categorized them into an interaction map showing their involvement in various biological processes. Consistent with previous reports, a large fraction of the acetylation sites are present on proteins involved in cellular metabolism. Interestingly, for the first time, many proteins involved in photosynthesis, including the subunits of phycocyanin (CpcA, CpcB, CpcC, and CpcG) and allophycocyanin (ApcA, ApcB, ApcD, ApcE, and ApcF), were found to be lysine acetylated, suggesting that lysine acetylation may play regulatory roles in the photosynthesis process. Six identified acetylated proteins associated with photosynthesis and carbon metabolism were further validated by immunoprecipitation and Western blotting. Our data provide the first global survey of lysine acetylation in cyanobacteria and reveal previously unappreciated roles of lysine acetylation in the regulation of photosynthesis. The provided data set may serve as an important resource for the functional analysis of lysine acetylation in cyanobacteria and facilitate the elucidation of the entire metabolic networks and photosynthesis process in this model cyanobacterium.

  19. Detecting The Expected Rate of Return Volatility of Financing Instruments of Indonesian Islamic Banking through GARCH Modeling (Generalized Autoregressive Conditional Heteroscedasticity

    Directory of Open Access Journals (Sweden)

    Nurul Huda

    2015-04-01

    Full Text Available Objective - Islamic banks are banks which its activities, both fund raising and funds distribution are on the basis of Islamic principles, namely buying and selling and profit sharing. Islamic banking is aimed at supporting the implementation of national development in order to improve justice, togetherness, and equitable distribution of welfare. In pursuit of supporting the implementation of national development, Islamic banking often faced stability problems of financing instruments being operated. In this case, it is measured by the gap between the actual rate of return and the expected rate of return. The individual actual RoR of this instrument will generate an expected rate of return. This raises the gap or difference between the actual rate of return and the expected rate of return of individual instruments, which in this case is called the abnormal rate of return. The stability of abnormal rate of return of individual instruments is certainly influenced by the stability of the expected rate of return. Expected rate of return has a volatility or fluctuation levels for each financing instrument. It is also a key element or material basis for the establishment of a variance of individual instruments. Variance in this case indicates the level of uncertainty of the rate of return. Individual variance is the origin of the instrument base for variance in the portfolio finance that further a portfolio analysis. So, this paper is going to analyze the level of expected RoR volatility as an initial step to see and predict the stability of the fluctuations in the rate of return of Indonesian Islamic financing instruments.Methods – Probability of Occurence, Expected Rate of Return (RoR and GARCH (Generalized Autoregressive Conditional Heteroscedasticity.Results - The expected RoR volatility of the murabaha and istishna financing instruments tend to be more volatile than expected RoR volatility of musharaka and qardh financing instruments

  20. Assessing the Efficacy of First-Aid Measures in Physalia sp. Envenomation, Using Solution- and Blood Agarose-Based Models

    Directory of Open Access Journals (Sweden)

    Christie L. Wilcox

    2017-04-01

    Full Text Available Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to whether vinegar use is appropriate (most current recommendations recommend against vinegar. We found that only a small percentage (≤1.0% of tentacle cnidae discharge during a sting event using an ex vivo tissue model which elicits spontaneous stinging from live cnidarian tentacles. We then tested a variety of rinse solutions on both Atlantic and Pacific Physalia species to determine if they elicit cnidae discharge, further investigating any that did not cause immediate significant discharge to determine if they are able to inhibit cnidae discharge in response to chemical and physical stimuli. We found commercially available vinegars, as well as the recently developed Sting No More® Spray, were the most effective rinse solutions, as they irreversibly inhibited cnidae discharge. However, even slight dilution of vinegar reduced its protective effects. Alcohols and folk remedies, such as urine, baking soda and shaving cream, caused varying amounts of immediate cnidae discharge and failed to inhibit further discharge, and thus likely worsen stings.

  1. Assessing the Efficacy of First-Aid Measures in Physalia sp. Envenomation, Using Solution- and Blood Agarose-Based Models

    Science.gov (United States)

    Wilcox, Christie L.; Headlam, Jasmine L.; Doyle, Thomas K.; Yanagihara, Angel A.

    2017-01-01

    Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to whether vinegar use is appropriate (most current recommendations recommend against vinegar). We found that only a small percentage (≤1.0%) of tentacle cnidae discharge during a sting event using an ex vivo tissue model which elicits spontaneous stinging from live cnidarian tentacles. We then tested a variety of rinse solutions on both Atlantic and Pacific Physalia species to determine if they elicit cnidae discharge, further investigating any that did not cause immediate significant discharge to determine if they are able to inhibit cnidae discharge in response to chemical and physical stimuli. We found commercially available vinegars, as well as the recently developed Sting No More® Spray, were the most effective rinse solutions, as they irreversibly inhibited cnidae discharge. However, even slight dilution of vinegar reduced its protective effects. Alcohols and folk remedies, such as urine, baking soda and shaving cream, caused varying amounts of immediate cnidae discharge and failed to inhibit further discharge, and thus likely worsen stings. PMID:28445412

  2. A cultural and social cognitive model of differences in acculturation orientations, alcohol expectancies, and alcohol-related risk behaviors among Hispanic college students.

    Science.gov (United States)

    Des Rosiers, Sabrina E; Schwartz, Seth J; Zamboanga, Byron L; Ham, Lindsay S; Huang, Shi

    2013-04-01

    The present study used a cultural and social cognitive conceptual framework to investigate whether alcohol expectancies and valuations would mediate the associations between specific acculturation orientations and alcohol-related risk behaviors. The sample comprised 1,527 Hispanic students attending colleges and universities in diverse regions of the United States. Respondents completed self-report measures of Hispanic and American cultural practices; alcohol expectancies and valuations; and self-reported frequency of hazardous alcohol use, binge drinking, sexual activity under the influence of alcohol, driving under the influence of alcohol, and riding with a drunk driver. Latent class analysis was used to classify participants into acculturation orientations. Results indicated that acculturation orientations were differentially associated with alcohol-related risk outcomes, with separated bicultural and low bicultural orientations inversely related to all of the alcohol-related risk behaviors except for riding with a drunk driver. Negative expectancy valuations were positively associated with endorsement of binge drinking and drunk driving and negative expectancies were negatively associated with binge drinking, drunk driving, and riding with a drunk driver. With the exception of sexual activity under the influence of alcohol, the associations between acculturation orientations and alcohol-related risk behaviors were partially mediated by positive alcohol expectancies. Our findings provided relevant data that are informative for preventing alcohol and related risk behaviors among Hispanic college students. © 2012 Wiley Periodicals, Inc.

  3. Expectancies as core features of mental disorders.

    Science.gov (United States)

    Rief, Winfried; Glombiewski, Julia A; Gollwitzer, Mario; Schubö, Anna; Schwarting, Rainer; Thorwart, Anna

    2015-09-01

    Expectancies are core features of mental disorders, and change in expectations is therefore one of the core mechanisms of treatment in psychiatry. We aim to improve our understanding of expectancies by summarizing factors that contribute to their development, persistence, and modification. We pay particular attention to the issue of persistence of expectancies despite experiences that contradict them. Based on recent research findings, we propose a new model for expectation persistence and expectation change. When expectations are established, effects are evident in neural and other biological systems, for example, via anticipatory reactions, different biological reactions to expected versus unexpected stimuli, etc. Psychological 'immunization' and 'assimilation', implicit self-confirming processes, and stability of biological processes help us to better understand why expectancies persist even in the presence of expectation violations. Learning theory, attentional processes, social influences, and biological determinants contribute to the development, persistence, and modification of expectancies. Psychological interventions should focus on optimizing expectation violation to achieve optimal treatment outcome and to avoid treatment failures.

  4. Grade Expectations: Rationality and Overconfidence

    Science.gov (United States)

    Magnus, Jan R.; Peresetsky, Anatoly A.

    2018-01-01

    Confidence and overconfidence are essential aspects of human nature, but measuring (over)confidence is not easy. Our approach is to consider students' forecasts of their exam grades. Part of a student's grade expectation is based on the student's previous academic achievements; what remains can be interpreted as (over)confidence. Our results are based on a sample of about 500 second-year undergraduate students enrolled in a statistics course in Moscow. The course contains three exams and each student produces a forecast for each of the three exams. Our models allow us to estimate overconfidence quantitatively. Using these models we find that students' expectations are not rational and that most students are overconfident, in agreement with the general literature. Less obvious is that overconfidence helps: given the same academic achievement students with larger confidence obtain higher exam grades. Female students are less overconfident than male students, their forecasts are more rational, and they are also faster learners in the sense that they adjust their expectations more rapidly. PMID:29375449

  5. Grade Expectations: Rationality and Overconfidence

    Directory of Open Access Journals (Sweden)

    Jan R. Magnus

    2018-01-01

    Full Text Available Confidence and overconfidence are essential aspects of human nature, but measuring (overconfidence is not easy. Our approach is to consider students' forecasts of their exam grades. Part of a student's grade expectation is based on the student's previous academic achievements; what remains can be interpreted as (overconfidence. Our results are based on a sample of about 500 second-year undergraduate students enrolled in a statistics course in Moscow. The course contains three exams and each student produces a forecast for each of the three exams. Our models allow us to estimate overconfidence quantitatively. Using these models we find that students' expectations are not rational and that most students are overconfident, in agreement with the general literature. Less obvious is that overconfidence helps: given the same academic achievement students with larger confidence obtain higher exam grades. Female students are less overconfident than male students, their forecasts are more rational, and they are also faster learners in the sense that they adjust their expectations more rapidly.

  6. Price expectations and petroleum development

    International Nuclear Information System (INIS)

    Pollio, G.; Marian, W.S.

    1991-01-01

    In the first section of this paper, the authors present a highly stylized model of the world oil market that explicitly incorporates both expectative and financial effects. The model generates the extremely interesting result that actual future price outcomes are inversely related to prevailing price expectations, owing to fluctuation in the level and timing of industry investment expenditure. Given the importance of price expectations, it is surprising that the topic has received such scant attention. The authors therefore present in the second section of selective survey of the various measures that have been proposed and used in the literature, as well as an assessment of the value of potentially new indices and market prices for existing hydrocarbon reserves, for example. In the final section of the paper, we discuss the extent to which financial innovation, in the form of commodity-linked products-such as swaps, caps, collars, and so forth-are transforming the oil market, enabling all market segments to manage price uncertainty far more effectively than was ever possible in the past

  7. Task Force 1. Report of the Task Force on Patient Expectations, Core Values, Reintegration, and the New Model of Family Medicine

    Science.gov (United States)

    Green, Larry A.; Graham, Robert; Bagley, Bruce; Kilo, Charles M.; Spann, Stephen J.; Bogdewic, Stephen P.; Swanson, John

    2004-01-01

    BACKGROUND To lay the groundwork for the development of a comprehensive strategy to transform and renew the specialty of family medicine, this Future of Family Medicine task force was charged with identifying the core values of family medicine, developing proposals to reform family medicine to meet consumer expectations, and determining systems of care to be delivered by family medicine in the future. METHODS A diverse, multidisciplinary task force representing a broad spectrum of perspectives and expertise analyzed and discussed published literature; findings from surveys, interviews, and focus groups compiled by research firms contracted to the Future of Family Medicine project; and analyses from The Robert Graham Center, professional societies in the United States and abroad, and others. Through meetings, conference calls, and writing, and revision of a series of subcommittee reports, the entire task force reached consensus on its conclusions and recommendations. These were reviewed by an external panel of experts and revisions were made accordingly. MAJOR FINDINGS After delivering on its promise to reverse the decline of general practice in the United States, family medicine and the nation face additional challenges to assure all people receive care that is safe, effective, patient-centered, timely, efficient, and equitable. Challenges the discipline needs to address to improve family physicians’ ability to make important further contributions include developing a broader, more accurate understanding of the specialty among the public and other health professionals, addressing the wide scope and variance in practice types within family medicine, winning respect for the specialty in academic circles, making family medicine a more attractive career option, and dealing with the perception that family medicine is not solidly grounded in science and technology. The task force set forth a proposed identity statement for family medicine, a basket of services that

  8. Referral expectations of radiology

    International Nuclear Information System (INIS)

    Smith, W.L.; Altmaier, E.; Berberoglu, L.; Morris, K.

    1989-01-01

    The expectation of the referring physician are key to developing a successful practice in radiology. Structured interviews with 17 clinicians in both community care and academic practice documented that accuracy of the radiologic report was the single most important factor in clinician satisfaction. Data intercorrelation showed that accuracy of report correlated with frequency of referral (r = .49). Overall satisfaction of the referring physician with radiology correlated with accuracy (r = .69), patient satisfaction (r = .36), and efficiency in archiving (r = .42). These data may be weighted by departmental managers to allocate resources for improving referring physician satisfaction

  9. Agreeing on expectations

    DEFF Research Database (Denmark)

    Nielsen, Christian; Bentsen, Martin Juul

    Commitment and trust are often mentioned as important aspects of creating a perception of reliability between counterparts. In the context of university-industry collaborations (UICs), agreeing on ambitions and expectations are adamant to achieving outcomes that are equally valuable to all parties...... involved. Despite this, our initial probing indicated that such covenants rarely exist. As such, this paper draws on project management theory and proposes the possibility of structuring assessments of potential partners before university-industry collaborations are brought to life. Our analysis suggests...

  10. Expectancy-Value Models for the STEM Persistence Plans of Ninth-Grade, High-Ability Students: A Comparison between Black, Hispanic, and White Students

    Science.gov (United States)

    Andersen, Lori; Ward, Thomas J.

    2014-01-01

    Group differences in the effects of the expectancies and values that high-ability students have for science and mathematics on plans to persist in science, technology, engineering, and mathematics (STEM) were investigated. A nationally representative sample of ninth-grade students, the High School Longitudinal Study of 2009 (HSLS: 2009; n =…

  11. Probability via expectation

    CERN Document Server

    Whittle, Peter

    1992-01-01

    This book is a complete revision of the earlier work Probability which ap­ peared in 1970. While revised so radically and incorporating so much new material as to amount to a new text, it preserves both the aim and the approach of the original. That aim was stated as the provision of a 'first text in probability, de­ manding a reasonable but not extensive knowledge of mathematics, and taking the reader to what one might describe as a good intermediate level'. In doing so it attempted to break away from stereotyped applications, and consider applications of a more novel and significant character. The particular novelty of the approach was that expectation was taken as the prime concept, and the concept of expectation axiomatized rather than that of a probability measure. In the preface to the original text of 1970 (reproduced below, together with that to the Russian edition of 1982) I listed what I saw as the advantages of the approach in as unlaboured a fashion as I could. I also took the view that the text...

  12. Gender Roles and Expectations

    Directory of Open Access Journals (Sweden)

    Susana A. Eisenchlas

    2013-09-01

    Full Text Available One consequence of the advent of cyber communication is that increasing numbers of people go online to ask for, obtain, and presumably act upon advice dispensed by unknown peers. Just as advice seekers may not have access to information about the identities, ideologies, and other personal characteristics of advice givers, advice givers are equally ignorant about their interlocutors except for the bits of demographic information that the latter may offer freely. In the present study, that information concerns sex. As the sex of the advice seeker may be the only, or the predominant, contextual variable at hand, it is expected that that identifier will guide advice givers in formulating their advice. The aim of this project is to investigate whether and how the sex of advice givers and receivers affects the type of advice, through the empirical analysis of a corpus of web-based Spanish language forums on personal relationship difficulties. The data revealed that, in the absence of individuating information beyond that implicit in the advice request, internalized gender expectations along the lines of agency and communality are the sources from which advice givers draw to guide their counsel. This is despite the trend in discursive practices used in formulating advice, suggesting greater language convergence across sexes.

  13. ATLAS: Exceeding all expectations

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    “One year ago it would have been impossible for us to guess that the machine and the experiments could achieve so much so quickly”, says Fabiola Gianotti, ATLAS spokesperson. The whole chain – from collision to data analysis – has worked remarkably well in ATLAS.   The first LHC proton run undoubtedly exceeded expectations for the ATLAS experiment. “ATLAS has worked very well since the beginning. Its overall data-taking efficiency is greater than 90%”, says Fabiola Gianotti. “The quality and maturity of the reconstruction and simulation software turned out to be better than we expected for this initial stage of the experiment. The Grid is a great success, and right from the beginning it has allowed members of the collaboration all over the world to participate in the data analysis in an effective and timely manner, and to deliver physics results very quickly”. In just a few months of data taking, ATLAS has observed t...

  14. Gamma-Gompertz life expectancy at birth

    Directory of Open Access Journals (Sweden)

    Trifon I. Missov

    2013-02-01

    Full Text Available BACKGROUND The gamma-Gompertz multiplicative frailty model is the most common parametric modelapplied to human mortality data at adult and old ages. The resulting life expectancy hasbeen calculated so far only numerically. OBJECTIVE Properties of the gamma-Gompertz distribution have not been thoroughly studied. The focusof the paper is to shed light onto its first moment or, demographically speaking, characterizelife expectancy resulting from a gamma-Gompertz force of mortality. The paperprovides an exact formula for gamma-Gompertz life expectancy at birth and a simplerhigh-accuracy approximation that can be used in practice for computational convenience.In addition, the article compares actual (life-table to model-based (gamma-Gompertzlife expectancy to assess on aggregate how many years of life expectancy are not captured(or overestimated by the gamma-Gompertz mortality mechanism. COMMENTS A closed-form expression for gamma-Gomeprtz life expectancy at birth contains a special(the hypergeometric function. It aids assessing the impact of gamma-Gompertz parameterson life expectancy values. The paper shows that a high-accuracy approximation canbe constructed by assuming an integer value for the shape parameter of the gamma distribution.A historical comparison between model-based and actual life expectancy forSwedish females reveals a gap that is decreasing to around 2 years from 1950 onwards.Looking at remaining life expectancies at ages 30 and 50, we see this gap almost disappearing.

  15. Green Decision Making: Sustainable Transport and Systemic Planning (SP)

    DEFF Research Database (Denmark)

    Leleur, Steen

    and infrastructure assessment and on the methodology and process of systemic planning (SP). SP theory development has interchanged with practical application and testing of the SP approach in a large number of cases. The word systemic in SP indicates that complex planning problems and provision of decision support...... in today’s strategic planning needs a focus on what may be addressed as systemic insights in balance with more conventional, systematically-based findings where causal linkages can be modelled and made use of. In practice this means that SP is based on a study-specific combination of hard (quantitative......) and soft (qualitative) operations research (OR) methods; especially the latter have a function as regards knowledge generation that relates to obtaining systemic insights. Furthermore, SP applies a process that drives group-based learning forward. The group should be formed with the different stakeholder...

  16. Energy providers: customer expectations

    International Nuclear Information System (INIS)

    Pridham, N.F.

    1997-01-01

    The deregulation of the gas and electric power industries, and how it will impact on customer service and pricing rates was discussed. This paper described the present situation, reviewed core competencies, and outlined future expectations. The bottom line is that major energy consumers are very conscious of energy costs and go to great lengths to keep them under control. At the same time, solutions proposed to reduce energy costs must benefit all classes of consumers, be they industrial, commercial, institutional or residential. Deregulation and competition at an accelerated pace is the most likely answer. This may be forced by external forces such as foreign energy providers who are eager to enter the Canadian energy market. It is also likely that the competition and convergence between gas and electricity is just the beginning, and may well be overshadowed by other deregulated industries as they determine their core competencies

  17. Customer experiences and expectations

    International Nuclear Information System (INIS)

    Morton, C. R.

    1997-01-01

    Customer experiences and expectations from competition and cogeneration in the power industry were reviewed by Charles Morton, Director of Energy at CPC International, by describing Casco's decision to get into cogeneration in the early 1990s in three small corn milling plants in Cardinal, London and Port Colborne, Ontario, mainly as result of the threat of a 40 per cent increase in power prices. He stressed that cost competitiveness of cogeneration is entirely site-specific, but it is generally more attractive in larger facilities that operate 24 hours a day, where grid power is expensive or unreliable. Because it is reliable, cogeneration holds out the prospect of increased production-up time, as well as offering a hedge against higher energy costs, reducing the company's variable costs when incoming revenues fall short of costs, and providing an additional tool in head-to-head competition

  18. Expectancy Theory in Media and Message Selection.

    Science.gov (United States)

    Van Leuven, Jim

    1981-01-01

    Argues for reversing emphasis on uses and gratifications research in favor of an expectancy model which holds that selection of a particular medium depends on (1) the expectation that the choice will be followed by a message of interest and (2) the importance of that message in satisfying user's values. (PD)

  19. Memory, expectation formation and scheduling choices

    NARCIS (Netherlands)

    Koster, P.R.; Peer, S.; Dekker, T.

    2015-01-01

    Limited memory capacity, retrieval constraints and anchoring are central to expectation formation processes. We develop a model of adaptive expectations where individuals are able to store only a finite number of past experiences of a stochastic state variable. Retrieval of these experiences is

  20. Macro Expectations, Aggregate Uncertainty, and Expected Term Premia

    DEFF Research Database (Denmark)

    Dick, Christian D.; Schmeling, Maik; Schrimpf, Andreas

    Based on individual expectations from the Survey of Professional Forecasters, we construct a realtime proxy for expected term premium changes on long-term bonds. We empirically investigate the relation of these bond term premium expectations with expectations about key macroeconomic variables as ...

  1. A comparative study of expectant parents ' childbirth expectations.

    Science.gov (United States)

    Kao, Bi-Chin; Gau, Meei-Ling; Wu, Shian-Feng; Kuo, Bih-Jaw; Lee, Tsorng-Yeh

    2004-09-01

    The purpose of this study was to understand childbirth expectations and differences in childbirth expectations among expectant parents. For convenience sampling, 200 couples willing to participate in this study were chosen from two hospitals in central Taiwan. Inclusion criteria were at least 36 weeks of gestation, aged 18 and above, no prenatal complications, and willing to consent to participate in this study. Instruments used to collect data included basic demographic data and the Childbirth Expectations Questionnaire. Findings of the study revealed that (1) five factors were identified by expectant parents regarding childbirth expectations including the caregiving environment, expectation of labor pain, spousal support, control and participation, and medical and nursing support; (2) no general differences were identified in the childbirth expectations between expectant fathers and expectant mothers; and (3) expectant fathers with a higher socioeconomic status and who had received prenatal (childbirth) education had higher childbirth expectations, whereas mothers displayed no differences in demographic characteristics. The study results may help clinical healthcare providers better understand differences in expectations during labor and birth and childbirth expectations by expectant parents in order to improve the medical and nursing system and promote positive childbirth experiences and satisfaction for expectant parents.

  2. Reveromycins A and B from Streptomyces sp. 3–10: Antifungal activity against plant pathogenic fungi in vitro and in a strawberry food model system

    Science.gov (United States)

    This study was conducted to determine the antifungal activity of the metabolites from Streptomyces sp. 3–10, and to purify and identify the metabolites. Meanwhile, the taxonomic status of strain 3–10 was re-evaluated. The cultural filtrates of strain 3–10 in potato dextrose broth were extract...

  3. An integrated microalgal growth model and its application to optimize the biomass production of Scenedesmus sp. LX1 in open pond under the nutrient level of domestic secondary effluent.

    Science.gov (United States)

    Wu, Yin-Hu; Li, Xin; Yu, Yin; Hu, Hong-Ying; Zhang, Tian-Yuan; Li, Feng-Min

    2013-09-01

    Microalgal growth is the key to the coupled system of wastewater treatment and microalgal biomass production. In this study, Monod model, Droop model and Steele model were incorporated to obtain an integrated growth model describing the combined effects of nitrogen, phosphorus and light intensity on the growth rate of Scenedesmus sp. LX1. The model parameters were obtained via fitting experimental data to these classical models. Furthermore, the biomass production of Scenedesmus sp. LX1 in open pond under nutrient level of secondary effluent was analyzed based on the integrated model, predicting a maximal microalgal biomass production rate about 20 g m(-2) d(-1). In order to optimize the biomass production of open pond the microalgal biomass concentration, light intensity on the surface of open pond, total depth of culture medium and hydraulic retention time should be 500 g m(-3), 16,000 lx, 0.2 m and 5.2 d in the conditions of this study, respectively. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Cryptosporidium sp. in lizards

    Czech Academy of Sciences Publication Activity Database

    Koudela, Břetislav; Modrý, D.

    1998-01-01

    Roč. 45, č. 1 (1998), s. 8 ISSN 1066-5234. [Cryptosporidium sp. in lazards. 01.01.1998-02.01.1998, Praha] R&D Projects: GA ČR GA508/95/0273; GA AV ČR IPP2020702 Subject RIV: fp - Other Medical Disciplines

  5. Stability of sp{sup 2}-carbon single layer nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, L N; Bursill, L A [University of Melbourne, Parkville, VIC (Australia). School of Physics

    1997-12-31

    Full text: Sp{sup 2}-hybridised carbon is quite versatile in its ability to build atomic structures. Although graphite is the most common and best known sp{sup 2}-carbon compound, recent discoveries of the C{sub 60} molecule and the related nanotubes have shown that networks of three-fold coordinated carbon atoms may result in a wide range of geometries. This has led to the postulation that structures such as the negatively curved schwarzites and tori may also be synthesized. In particular, theoretical calculations have shown the cohesive energy of schwarzites to be higher than that of C{sub 60}. Presented here is an analytical model describing the energetics of the most common sp{sup 2}-carbon single nanostructures as well as the hypothetical P-schwarzite. An expression for the energy with respect to a flat graphite sheet is written as the sum of a strain energy term (arising from curving of the carbon network) and a dangling bond energy term (not negligible in an inert environment). The relative stability of carbon spheres, tubes, planes and minimal surfaces is then investigated as a function of the dangling bond energy. In an inert atmosphere (large dangling bond energy), the cylinder appears to be the most stable geometry up to a certain size (about 40 atoms only). Above this number of atoms, the sphere is found to be energetically favoured. In a reactive environment, flat sheets are found to have the lowest energy, as expected. The other structures appeared to be always less stable than tubes, spheres and planes. However, small proportions of negatively curved sheets may occur at high temperatures. These results are compared with known experimental facts

  6. Prediction error variance and expected response to selection, when selection is based on the best predictor - for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits

    DEFF Research Database (Denmark)

    Andersen, Anders Holst; Korsgaard, Inge Riis; Jensen, Just

    2002-01-01

    In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed...... or random effects). In the different models, expressions are given (when these can be found - otherwise unbiased estimates are given) for prediction error variance, accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non...... Gaussian traits are generalisations of the well-known formulas for Gaussian traits - and reflect, for Poisson mixed models and frailty models for survival data, the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part...

  7. Expectations from ethics

    International Nuclear Information System (INIS)

    Fleming, P.

    2008-01-01

    Prof. Patricia Fleming, centred her presentation on ethical expectations in regulating safety for future generations. The challenge is to find a just solution, one that provides for a defensible approach to inter-generational equity. The question on equity is about whether we are permitted to treat generations differently and to still meet the demands of justice. And the question must be asked regarding these differences: 'in what ways do they make a moral difference?' She asked the question regarding the exact meaning of the ethical principle 'Radioactive waste shall be managed in such a way that predicted impacts on the health of future generations will not be greater than relevant levels of impact that are acceptable today'. Some countries have proposed different standards for different time periods, either implicitly or explicitly. In doing so, have they preserved our standards of justice or have they abandoned them? Prof. Fleming identified six points to provide with some moral maps which might be used to negotiate our way to a just solution to the disposal of nuclear waste. (author)

  8. Stakeholder expectation and satisfaction in road maintenance

    NARCIS (Netherlands)

    Hietbrink, M.; Hartmann, Andreas; Dewulf, Geert P.M.R.

    2012-01-01

    Understanding the process of stakeholder satisfaction is a prerequisite for successful stakeholder management. The expectancy disconfirmation model describes the process of stakeholder satisfaction by relating customers’ satisfaction with a product or service to discrepancy between the perceived

  9. Retirement expectations and satisfaction with retirement provisions

    NARCIS (Netherlands)

    de Bresser, Jochem; van Soest, Arthur

    This paper investigates the relationship between subjective expectations regarding the replacement rate of income at retirement and several measures of pension satisfaction. We use panel data on Dutch employees, analyzed with fixed effects models, allowing for correlation between unobserved

  10. Using Expectancy Theory to Explain Performance Appraisal ...

    African Journals Online (AJOL)

    pc

    2018-03-05

    Mar 5, 2018 ... appraisal conducting style, the relation between the performance appraisal system and task ... the article first explains the theory model which is based expectancy theory. II. ... which in return lead to rewards. According to [12],.

  11. Partnership between painters and sculptors in 17th-century Spain: on model drawings by Francisco Rizi for an altarpiece of the Expectant Virgin

    Directory of Open Access Journals (Sweden)

    Lamas-Delgado, Eduardo

    2013-01-01

    Full Text Available This paper deals with a case study of the collaboration between sculptors and painters in the context of the construction of altarpieces in 17th-century Spain. It analyses a drawing by Francisco Rizi (Madrid, 1614-Escorial, 1685 in the British Museum depicting a sculptural group and fragments of an architectural framework, and relates it to two other drawings by the same artist in the National Library of Spain. They are identified as fragments of the design drawing of the former altarpiece of the Expectant Virgin in the church of the Calced Trinitarians in Madrid.

  12. Expectations from Society

    International Nuclear Information System (INIS)

    Blowers, A.

    2008-01-01

    Prof. A. Blowers observed that the social context within which radioactive waste management is considered has evolved over time. The early period where radioactive waste was a non-issue was succeeded by a period of intense conflict over solutions. The contemporary context is more consensual, in which solutions are sought that are both technically sound and socially acceptable. Among the major issues is that of inter-generational equity embraced in the question: how long can or should our responsibility to the future extend? He pointed out the differences in timescales. On the one hand, geo-scientific timescales are very long term, emphasizing the issue of how far into the future it is possible to make predictions about repository safety. By contrast, socio cultural timescales are much shorter, focusing on the foreseeable future of one or two generations and raising the issue of how far into the future we should be concerned. He listed. the primary expectations from society which are: safety and security to alleviate undue burdens to future generations and flexibility in order to enable the future generations to have a stake in decision making. The need to reconcile the two had led to a contemporary emphasis on phased geological disposal incorporating retrievability. However, the long timescales for implementation of disposal provided for sufficient flexibility without the need for retrievability. Future generations would inevitably have sold stake in decision making. Prof. A.. Blowers pointed out that society is also concerned with participation in decision making for implementation. The key elements for success are: openness and transparency, staged process, participation, partnership, benefits to enhance the well being of communities and a democratic framework for decision making, including the ratification of key decisions and the right for communities to withdraw from the process up to a predetermined point. This approach for decision making may also have

  13. Expectation Consistent Approximate Inference

    DEFF Research Database (Denmark)

    Opper, Manfred; Winther, Ole

    2005-01-01

    We propose a novel framework for approximations to intractable probabilistic models which is based on a free energy formulation. The approximation can be understood from replacing an average over the original intractable distribution with a tractable one. It requires two tractable probability dis...

  14. Aligning Resources with Expectations

    Science.gov (United States)

    Tran, Samantha

    2006-01-01

    In this article, the author discusses that the ability to clearly link resources, activities and goals in a rational and logical manner is a model that many educators and school leaders would welcome. She also states that in the 1990s, when the state moved in the direction of standards and accountability, part of the thinking was that public…

  15. Expected Business Conditions and Bond Risk Premia

    DEFF Research Database (Denmark)

    Eriksen, Jonas Nygaard

    This paper studies the predictability of bond risk premia by means of expectations to future business conditions using survey forecasts from the Survey of Professional Forecasters. We show that expected business conditions consistently affect excess bond returns and that the inclusion of expected...... business conditions in standard predictive regressions improve forecast performance relative to models using information derived from the current term structure or macroeconomic variables. The results are confirmed in a real-time out-of-sample exercise, where the predictive accuracy of the models...... is evaluated both statistically and from the perspective of a mean-variance investor that trades in the bond market....

  16. Dynamic decision making without expected utility

    DEFF Research Database (Denmark)

    Nielsen, Thomas Dyhre; Jaffray, Jean-Yves

    2006-01-01

    Non-expected utility theories, such as rank dependent utility (RDU) theory, have been proposed as alternative models to EU theory in decision making under risk. These models do not share the separability property of expected utility theory. This implies that, in a decision tree, if the reduction...... maker’s discordant goals at the different decision nodes. Relative to the computations involved in the standard expected utility evaluation of a decision problem, the main computational increase is due to the identification of non-dominated strategies by linear programming. A simulation, using the rank...

  17. Expectations from implementers

    International Nuclear Information System (INIS)

    Biurrun, E.; Zuidema, P.

    2008-01-01

    Enrique Biurrun (DBE) presented the expectations from the implementer. He explained that the implementer needs a framework to successfully develop a repository which means the definition of requirements and guidance (for repository system development, analysis, licences, etc.) as well as the decision-making process (stepwise approach, roles of different players, etc.). He also needs a reasonable stability of the regulatory system. The regulatory framework should be developed in a clear, reasonable and consistent manner. In the context of the long duration of the project (100 years) there will be technological progress. In that context E. Biurrun asked what is the meaning of best practice. How can one deal with judgmental issues in a step-wise approach? Regulatory criteria and guidance must deal with the repository system for which an iterative process is necessary where dialogue is needed with the regulator despite the need to maintain his independence. The safety case, which is a periodic documentation of the status of the project, must provide a synthesis of the underlying scientific understanding and evidence and becomes part of the design process through feedback. E. Biurrun pointed out that safety is not calculated or assessed, but designed and built into the repository system (by geological and engineered barriers). He stressed the importance of the operational aspects since the implementer has to build and operate the repository safely. He asked the question: is it 'Ethical' to buy 'peace of mind' of some stakeholders with casualties of the implementer's staff because of mining accidents if the repository is left open during a phase of reversibility. The implementer needs dependable criteria, legal security and investment security. He interpreted the 'Precautionary principle' as meaning 'do it now'. Long-lasting solutions are very uncertain. Will we heave the money and the technology to do it later? He made some reflections regarding the ethical need to

  18. Final predictions of ambient conditions along the east-west cross drift using the 3-D UZ site-scale model. Level 4 milestone SP33ABM4

    International Nuclear Information System (INIS)

    Ritcey, A.C.; Sonnenthal, E.L.; Wu, Y.S.; Haukwa, C.; Bodvarsson, G.S.

    1998-01-01

    In 1998, the Yucca Mountain Site Characterization Project (YMP) is expected to continue construction of an East-West Cross Drift. The 5-meter diameter drift will extend from the North Ramp of the Exploratory Studies Facility (ESF), near Station 19+92, southwest through the repository block, and over to and through the Solitario Canyon Fault. This drift is part of a program designed to enhance characterization of Yucca Mountain and to complement existing surface-based and ESF testing studies. The objective of this milestone is to use the three-dimensional (3-D) unsaturated zone (UZ) site-scale model to predict ambient conditions along the East-West Cross Drift. These predictions provide scientists and engineers with a priori information that can support design and construction of the East-West Cross Drift and associated testing program. The predictions also provide, when compared with data collected after drift construction, an opportunity to test and verify the calibration of the 3-D UZ site-scale model

  19. The Effect of Acupuncture to SP6 on Skin Temperature Changes of SP6 and SP10: An Observation of “Deqi”

    Directory of Open Access Journals (Sweden)

    Jia-Min Yang

    2014-01-01

    Full Text Available Background. Deqi sensation is a complex but an important component for acupuncture effect. In this study, we tried to observe the relationship between Deqi and skin temperature changes and whether there was some relativity between Deqi and needle stimulations on cold congealing and dysmenorrhea rat model. Thirty-two female Sprague Dawley (SD rats were randomly divided into four groups (Saline Control Group, Model Group, Group A with strong stimulation, and Group B with small stimulation. Group A and Group B were performed with different stimulations. We found that, compared with saline control group, model group, and Group B, Group A showed that the skin temperature changes on right acupoint SP6 and SP10 increased significantly at 5 min–10 min interval. The skin temperature changes on left SP6 decreased at instant–5 min interval. The skin temperature changes on right SP10 decreased significantly at instant–5 min interval and 10 min–20 min interval. Thermogenic action along Spleen Meridian of Foot Greater Yin was manifested as simultaneous skin temperature increase on right SP6 and SP10 at 5 min–10 min interval after needling SP6, which was helpful to illustrate the relationship between the characteristic of Deqi and needle stimulations.

  20. Identification of microbial carotenoids and isoprenoid quinones from Rhodococcus sp. B7740 and its stability in the presence of iron in model gastric conditions.

    Science.gov (United States)

    Chen, Yashu; Xie, Bijun; Yang, Jifang; Chen, Jigang; Sun, Zhida

    2018-02-01

    Rhodococcus sp. B7740 is a newfound bacterium which was isolated from 25m deep seawater in the arctic. In this paper, Rhodococcus sp. B7740 was firstly discovered to produce abundant natural isoprenoids, including ubiquinone-4(UQ-4), 13 kinds of menaquinones, three rare aromatic carotenoids and more than one common carotenoid. These compounds were identified by UV-Visible, HPLC-APCI-MS/MS and HRMS spectra. Results demonstrated that Rhodococcus sp. B7740 might be a worthy source of natural isoprenoids especially for scarce aromatic carotenoids. Among them, isorenieratene with 528.3762Da (calculated for 528.3756Da, error: 1.1ppm), a carotenoid with aromatic ring, was purified by HSCCC. The stability of isorenieratene under the mimical gastric conditions was measured compared with common dietary carotenoids, β-carotene and lutein. Unlike β-carotene and lutein, isorenieratene exhibited rather stable in the presence of free iron or heme iron. Its high retention rate in gastrointestinal tract after ingestion indicates the benefits for health. Copyright © 2017. Published by Elsevier Ltd.

  1. Social gradient in life expectancy and health expectancy in Denmark

    DEFF Research Database (Denmark)

    Brønnum-Hansen, Henrik; Andersen, Otto; Kjøller, Mette

    2004-01-01

    Health status of a population can be evaluated by health expectancy expressed as average lifetime in various states of health. The purpose of the study was to compare health expectancy in population groups at high, medium and low educational levels.......Health status of a population can be evaluated by health expectancy expressed as average lifetime in various states of health. The purpose of the study was to compare health expectancy in population groups at high, medium and low educational levels....

  2. The Higgs and the expectation value of the number of elementary particles in a supersymmetric extensions of the standard model of high energy physics

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2005-01-01

    Supersymmetry, colours and chirality are utilized to develop three minimally extended versions of the standard model. Based on these models, it is possible to predict that few new elementary particles are likely to be found experimentally at an energy scale which is very modestly above that of the electroweak. Connections to the 8064 massless states of Heterotic string theory are also discussed

  3. A Micro-simulation model of updating expected travel time in provision of travel information : A bayesian belief approach implemented in a multi-state supernetwork

    NARCIS (Netherlands)

    Parvaneh, Z.; Liao, F.; Arentze, T.A.; Timmermans, H.J.P.; Shakshuki, Elhadi; Yasar, Ansar

    2014-01-01

    This study introduces a model of individual belief updating of subjective travel times as a function of the provision of different types of travel information. Travel information includes real-time prescriptive or descriptive, and public or personal information. The model is embedded in a

  4. Comparison of expected treatment outcomes, obtained using risk models and international guidelines, with observed treatment outcomes in a Dutch cohort of patients with non-muscle-invasive bladder cancer treated with intravesical chemotherapy.

    Science.gov (United States)

    Lammers, Rianne J M; Palou, Joan; Witjes, Wim P J; Janzing-Pastors, Maria H D; Caris, Christien T M; Witjes, J Alfred

    2014-08-01

    To compare the risks according to the American Urological Association (AUA), EAU, European Organization for Research and Treatment of Cancer (EORTC) and Club Urológico Español de Tratamiento Oncologico (CUETO) classifications with real outcomes in a cohort of patients in the Netherlands, and to confirm that patients who were undertreated according to these risk models have worse outcomes than adequately treated patients. Patients treated with complete transurethral resection of bladder tumour and intravesical chemotherapy were included. Not all patients would have received intravesical chemotherapy had they been treated to current standards, and thus comparison of the observed outcomes in our Dutch cohort vs expected outcomes based on the EORTC risk tables and CUETO scoring model was possible. The cohort was reclassified according to the definitions of five index patients (IPs), as defined by the AUA guidelines, and three risk groups, defined according to the EAU guidelines, to compare the outcomes of undertreated patients with those of adequately treated patients. A total of 1001 patients were available for comparison with the AUA definitions and 728 patients were available for comparison with the EORTC and CUETO models. There was a large overlap between the observed outcomes and expected recurrence and progression probabilities when comparison was made using the EORTC risk tables. The observed recurrence outcomes were in general higher than the expected probabilities according to the CUETO risk classification, especially in the long term. No differences in progression were found when comparing these two models to the Dutch cohort. Patients who were undertreated according to the guidelines showed, in general, a higher risk of developing recurrence and progression. Limitations are i.a. its retrospective nature and the differences in grading system. Comparisons between the observed outcomes in our Dutch cohort and the expected outcomes based on EAU and CUETO risk

  5. Testing the scalar expectancy theory (SET) and the learning-to-time model (LeT) in a double bisection task.

    Science.gov (United States)

    Machado, Armando; Pata, Paulo

    2005-02-01

    Two theories of timing, scalar expectancy theory (SET) and learning-to-time (LeT), make substantially different assumptions about what animals learn in temporal tasks. In a test of these assumptions, pigeons learned two temporal discriminations. On Type 1 trials, they learned to choose a red key after a 1-sec signal and a green key after a 4-sec signal; on Type 2 trials, they learned to choose a blue key after a 4-sec signal and a yellow key after either an 8-sec signal (Group 8) or a 16-sec signal (Group 16). Then, the birds were exposed to signals 1 sec, 4 sec, and 16 sec in length and given a choice between novel key combinations (red or green vs. blue or yellow). The choice between the green key and the blue key was of particular significance because both keys were associated with the same 4-sec signal. Whereas SET predicted no effect of the test signal duration on choice, LeT predicted that preference for green would increase monotonically with the length of the signal but would do so faster for Group 8 than for Group 16. The results were consistent with LeT, but not with SET.

  6. Effect of garlic solution to Bacillus sp. removal

    Science.gov (United States)

    Zainol, N.; Rahim, S. R.

    2018-04-01

    Biofilm is a microbial derived sessile community characterized by cells that are irreversibly attached to a substratum or interface to each other, embedded in a matrix of extracellular polymeric substances that they have produced. Bacillus sp. was used as biofilm model in this study. The purpose of this study is to determine the effect of Garlic solution in term of ratio of water and Garlic solution (W/G) and ratio of Garlic solution to Bacillus sp. (GS/B) on Bacillus sp removal. Garlic solution was used to remove Bacillus sp. In this study, Garlic solution was prepared by crushing the garlic and mixed it with water. the Garlic solution was added into Bacillus sp. mixture and mixed well. The mixture then was spread on nutrient agar. The Bacillus sp. weight on agar plate was measured by using dry weight measurement method. In this study, initially Garlic solution volume and Garlic solution concentration were studied using one factor at time (OFAT). Later two-level-factorial analysis was done to determine the most contributing factor in Bacillus sp. removal. Design Expert software (Version 7) was used to construct experimental table where all the factors were randomized. Bacilus sp removal was ranging between 42.13% to 99.6%. The analysis of the results showed that at W/G of 1:1, Bacillus sp. removal increased when more Garlic solution was added to Bacillus sp. Effect of Garlic solution to Bacillus sp. will be understood which in turn may be beneficial for the industrial purpose.

  7. Perceptual grouping effects on cursor movement expectations.

    Science.gov (United States)

    Dorneich, Michael C; Hamblin, Christopher J; Lancaster, Jeff A; Olofinboba, Olu

    2014-05-01

    Two studies were conducted to develop an understanding of factors that drive user expectations when navigating between discrete elements on a display via a limited degree-of-freedom cursor control device. For the Orion Crew Exploration Vehicle spacecraft, a free-floating cursor with a graphical user interface (GUI) would require an unachievable level of accuracy due to expected acceleration and vibration conditions during dynamic phases of flight. Therefore, Orion program proposed using a "caged" cursor to "jump" from one controllable element (node) on the GUI to another. However, nodes are not likely to be arranged on a rectilinear grid, and so movements between nodes are not obvious. Proximity between nodes, direction of nodes relative to each other, and context features may all contribute to user cursor movement expectations. In an initial study, we examined user expectations based on the nodes themselves. In a second study, we examined the effect of context features on user expectations. The studies established that perceptual grouping effects influence expectations to varying degrees. Based on these results, a simple rule set was developed to support users in building a straightforward mental model that closely matches their natural expectations for cursor movement. The results will help designers of display formats take advantage of the natural context-driven cursor movement expectations of users to reduce navigation errors, increase usability, and decrease access time. The rules set and guidelines tie theory to practice and can be applied in environments where vibration or acceleration are significant, including spacecraft, aircraft, and automobiles.

  8. Control of Branchionus sp. and Amoeba sp. in cultures of Arthrospira sp. Control de Branchionus sp. y Amoeba sp. en cultivos de Arthrospira sp.

    Directory of Open Access Journals (Sweden)

    Carlos Méndez

    2012-09-01

    Full Text Available Cultivation of cyanobacterium Arthrospira sp. has been developed in many countries for the production of proteins, pigments and other compounds. Outdoor mass cultures are often affected by biological contamination, drastically reducing productivity as far as bringing death. This study evaluates the control of Branchionus sp. and Amoeba sp. with two chemical compounds: urea (U and ammonium bicarbonate (AB, in laboratory conditions and outdoor mass culture of Arthrospira sp. The lethal concentration 100 (LC100 at 24 h for Branchionus sp. and Amoeba sp. determined was of 60-80 mg L-1 (U and 100-150 mg L-1 (AB. The average effective inhibition concentration for 50% of the population (IC50 in Arthrospira sp., after 72 h, was 80 mg L-1 (U and 150 mg L-1 (AB. The application of doses of 60 mg L-1 (U or 100 mg L-1 (AB in the outdoor mass culture of this contaminated microalga, completely inhibited grazing and did not affect the growth of Arthrospira sp. but rather promoted rapid recovery of algal density at levels prior to infestation. These compounds provided an economical and effective control of predators in cultures of Arthrospira sp.El cultivo de la cianobacteria Arthrospira sp. ha sido desarrollado en muchos países para la obtención de proteínas, pigmentos y otros compuestos. Cultivo que a nivel industrial se ve afectado frecuentemente por contaminación biológica, reduciendo drásticamente la productividad hasta causar la muerte. Este estudio evalúa el control de Branchionus sp. y de Amoeba sp. con dos compuestos químicos, la urea (U y bicarbonato de amonio (AB en cultivos de Arthrospira sp. La concentración letal 100 (LC100 determinada a las 24 h para Branchionus sp. y Amoeba sp. fue de 60-80 mg L-1 (U y 100-150 mg L-1 (AB. La concentración media de inhibición efectiva, después de 72 h, para el 50% de la población (IC50 en Arthrospira fue de 80 mg L-1 (U y 150 mg L-1 (AB. La aplicación de dosis de 60 mg L-1 (U ó 100 mg L-1 (AB en

  9. Biosorption of uranium by Azolla, SP, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Ludmila C.; Alves, Eliakim G.; Marumo, Julio T., E-mail: lcvieira@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Ferreira, Rafael V. de P., E-mail: rafael@itatijuca.com [Itatijuca Biotech, Sao Paulo, SP (Brazil); Canevesi, Rafael L.S.; Silva, Edson A., E-mail: edson.silva2@unioeste.br [Universidade Estadual do Oeste Parana (UNIOESTE), Toledo, PR (Brazil)

    2015-07-01

    Radioactive liquid waste needs special attention and requires suitable treatment before deposition. Among the potential technologies under development for the treatment of liquid radioactive wastes the biosorption has been highlighted by being an efficient and low cost technique. Biosorption process involves the exchange of ions contained in the biomass matrix by others present in solution. There are many biomasses that could be applied in treatment of radioactive wastes, for example, agricultural residues and macrophyte. The aim of this study is evaluate the ability of the Azolla sp., a floating aquatic plant, to absorb uranium in solution. Azolla sp. is a macrophyte that has been used to treat effluents containing heavy metals. The biosorption capacity of uranium by Azolla sp. was experimentally determined and modeled by isotherms. Experiments were performed to determine metal uptake, and then the solutions were analyzed by inductively coupled plasma optical emission spectrometry (ICP-OES). The isotherms applied to model the data was Langmuir, Freundlich, Sips Toth, Redlich Peternson, Two-Site-Langmuir, Radke Prausnitz to develop a technique for the treatment of radioactive liquid waste generated at the Nuclear and Energy Research Institute (IPEN-CNEN/SP), Brazil. (author)

  10. Biosorption of uranium by Azolla, SP, Brazil

    International Nuclear Information System (INIS)

    Vieira, Ludmila C.; Alves, Eliakim G.; Marumo, Julio T.; Ferreira, Rafael V. de P.; Canevesi, Rafael L.S.; Silva, Edson A.

    2015-01-01

    Radioactive liquid waste needs special attention and requires suitable treatment before deposition. Among the potential technologies under development for the treatment of liquid radioactive wastes the biosorption has been highlighted by being an efficient and low cost technique. Biosorption process involves the exchange of ions contained in the biomass matrix by others present in solution. There are many biomasses that could be applied in treatment of radioactive wastes, for example, agricultural residues and macrophyte. The aim of this study is evaluate the ability of the Azolla sp., a floating aquatic plant, to absorb uranium in solution. Azolla sp. is a macrophyte that has been used to treat effluents containing heavy metals. The biosorption capacity of uranium by Azolla sp. was experimentally determined and modeled by isotherms. Experiments were performed to determine metal uptake, and then the solutions were analyzed by inductively coupled plasma optical emission spectrometry (ICP-OES). The isotherms applied to model the data was Langmuir, Freundlich, Sips Toth, Redlich Peternson, Two-Site-Langmuir, Radke Prausnitz to develop a technique for the treatment of radioactive liquid waste generated at the Nuclear and Energy Research Institute (IPEN-CNEN/SP), Brazil. (author)

  11. Lessons from Learning to Have Rational Expectations

    OpenAIRE

    Lindh, Thomas

    1989-01-01

    This paper reviews a growing literature investigating how economic agents may learn rational expectations. Fully rational learning requires implausible initial information assumptions, therefore some form of bounded rationality has come into focus. Such learning models often converge to rational expectations equilibria within certain bounds. Convergence analysis has been much simplified by methods from adaptive control theory. Learning stability as a correspondence principle show some promise...

  12. Heterogeneus Inflation Expectations Learning and Market Outcomes

    OpenAIRE

    Carlos Madeira; Basit Zafar

    2012-01-01

    Using the panel component of the Michigan Survey of Consumers we estimate a learning model of inflation expectations, allowing for heterogeneous use of both private information and lifetime inflation experience. We find that women, ethnic minorities, and less educated agents have a higher degree of heterogeneity in their private information, and are slower to update their expectations. During the 2000s, consumers believe inflation to be more persistent in the short term, but temporary fluctua...

  13. Telaah Kritis Expectancy Theory Victor Harold Vroom

    OpenAIRE

    Anatan, Lina

    2010-01-01

    Expectancy theory has emerge as the dominant process theory of motivation, originally developed by Vroom is a theory explaining the process individual use to make decision on a various behavioral alternatives. The motivational force for a behavior, action, or task is a function of three distinctive perceptions: expectancy, instrumentality, and valance. The theory contains of two models: for the precition of valance of an outcome, and the other for the prediction of force toward behavior. It p...

  14. Gamma-Gompertz life expectancy at birth

    OpenAIRE

    Trifon I. Missov

    2013-01-01

    BACKGROUND The gamma-Gompertz multiplicative frailty model is the most common parametric modelapplied to human mortality data at adult and old ages. The resulting life expectancy hasbeen calculated so far only numerically. OBJECTIVE Properties of the gamma-Gompertz distribution have not been thoroughly studied. The focusof the paper is to shed light onto its first moment or, demographically speaking, characterizelife expectancy resulting from a gamma-Gompertz force of mortality. The paperprov...

  15. Patient (customer) expectations in hospitals.

    Science.gov (United States)

    Bostan, Sedat; Acuner, Taner; Yilmaz, Gökhan

    2007-06-01

    The expectations of patient are one of the determining factors of healthcare service. The purpose of this study is to measure the Patients' Expectations, based on Patient's Rights. This study was done with Likert-Survey in Trabzon population. The analyses showed that the level of the expectations of the patient was high on the factor of receiving information and at an acceptable level on the other factors. Statistical meaningfulness was determined between age, sex, education, health insurance, and the income of the family and the expectations of the patients (pstudy, the current legal regulations have higher standards than the expectations of the patients. The reason that the satisfaction of the patients high level is interpreted due to the fact that the level of the expectation is low. It is suggested that the educational and public awareness studies on the patients' rights must be done in order to increase the expectations of the patients.

  16. Model prediction for ranking lead-acid batteries according to expected lifetime in renewable energy systems and autonomous power-supply systems

    DEFF Research Database (Denmark)

    Schiffer, J.; Sauer, D.U.; Bindner, Henrik W.

    2007-01-01

    -of-discharge, the current rate, the existing acid stratification, and the time since the last full charging. The actual Ah throughput is continuously multiplied by a weight factor that represents the actual operating conditions. Even though the modelling approach is mainly heuristic, all of the effects that are taken...

  17. The Effects Of Gender, Engineering Identification, and Engineering Program Expectancy On Engineering Career Intentions: Applying Hierarchical Linear Modeling (HLM) In Engineering Education Research

    Science.gov (United States)

    Tendhar, Chosang; Paretti, Marie C.; Jones, Brett D.

    2017-01-01

    This study had three purposes and four hypotheses were tested. Three purposes: (1) To use hierarchical linear modeling (HLM) to investigate whether students' perceptions of their engineering career intentions changed over time; (2) To use HLM to test the effects of gender, engineering identification (the degree to which an individual values a…

  18. Simulations of Technology-Induced and Crisis-Led Stochastic and Chaotic Fluctuations in Higher Education Processes: A Model and a Case Study for Performance and Expected Employment

    Science.gov (United States)

    Ahmet, Kara

    2015-01-01

    This paper presents a simple model of the provision of higher educational services that considers and exemplifies nonlinear, stochastic, and potentially chaotic processes. I use the methods of system dynamics to simulate these processes in the context of a particular sociologically interesting case, namely that of the Turkish higher education…

  19. Macro Expectations, Aggregate Uncertainty, and Expected Term Premia

    DEFF Research Database (Denmark)

    Dick, Christian D.; Schmeling, Maik; Schrimpf, Andreas

    2013-01-01

    as well as aggregate macroeconomic uncertainty at the level of individual forecasters. We find that expected term premia are (i) time-varying and reasonably persistent, (ii) strongly related to expectations about future output growth, and (iii) positively affected by uncertainty about future output growth...... and in ation rates. Expectations about real macroeconomic variables seem to matter more than expectations about nominal factors. Additional findings on term structure factors suggest that the level and slope factor capture information related to uncertainty about real and nominal macroeconomic prospects...

  20. Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits

    Directory of Open Access Journals (Sweden)

    Jensen Just

    2002-05-01

    Full Text Available Abstract In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random effects. In the different models, expressions are given (when these can be found – otherwise unbiased estimates are given for prediction error variance, accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non Gaussian traits are generalisations of the well-known formulas for Gaussian traits – and reflect, for Poisson mixed models and frailty models for survival data, the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part of the model (heritability on the normally distributed level of the model or a generalised version of heritability plays a central role in these formulas.

  1. Expectancies and Self-Efficacy Mediate the Effects of Impulsivity on Marijuana Use Outcomes: An Application of the Acquired Preparedness Model

    OpenAIRE

    Hayaki, Jumi; Herman, Debra S.; Hagerty, Claire E.; de Dios, Marcel A.; Anderson, Bradley J.; Stein, Michael D.

    2010-01-01

    This study tests the acquired preparedness model (APM) to explain associations among trait impulsivity, social learning principles, and marijuana use outcomes in a community sample of female marijuana users. The APM states that individuals with high-risk dispositions are more likely to acquire certain types of learning that, in turn, instigate problematic substance use behaviors. In this study, three domains of psychosocial learning were tested: positive and negative marijuana use expectancie...

  2. CMS: Beyond all possible expectations

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    After having retraced the entire Standard Model up to the Top, the CMS collaboration is ready to go further and continue the success of what Guido Tonelli – its spokesperson – defines as a ‘magic year’. Things evolve fast at CMS, but scientists have taken up the challenge and are ready for the future.   ‘Enthusiasm’ is the word that best describes the feeling one gets when talking to Guido Tonelli. “In just a few months we have rediscovered the Standard Model and have gone even further by producing new results for cross-sections, placing new limits on the creation of heavy masses, making studies on the excited states of quarks, and seeking new resonances. We could not have expected so much such a short space of time. It’s fantastic”, he says. “We went through the learning phase very smoothly. Our detector was very quickly ready to do real physics and we were able to start to produce results almost ...

  3. Expectations and satisfactions of graduate students in administration at FEA-USP about training periods Expectativas e satisfação dos alunos de graduação em administração da FEA-USP/SP em relação aos estágios

    Directory of Open Access Journals (Sweden)

    Luiz Alberto Marcondes Homen de Mello e Castro

    2007-01-01

    Full Text Available Many companies began to consider their training programs as a means to acquire fundamental strategic qualifications to obtain and support competitive advantages. However, few companies were concerned about trainee needs and expectations related to these programs. The opinion of these trainees was surveyed about development opportunities so as to identify the expectations and needs that motivated those seeking these programs and how these aspects were satisfied. Semi-structured questionnaires were completed by FEA business students in the Supervised Training course. After scoring, content analysis was conducted to support qualitative investigation of individual comments. Results disclosed that students expected to apply their acquired education in the real company world so as to grow professionally and achieve recognition inside and outside the company. Further trainees showed motivation to achieve self-accomplishment once the preceding levels of the Maslow hierarchy had been satisfied and indicated that companies offered such opportunities.Muitas empresas começaram a pensar os seus programas de estágio como meio de adquirir competências estratégicas fundamentais para sustentar e criar vantagens competitivas. Porém, poucas companhias estão se preocupando com o outro lado da mesa, com as necessidades e expectativas dos clientes desses programas. Assim, este estudo objetivou levantar a opinião dos estagiários sobre as oportunidades de desenvolvimento oferecidas pelas empresas e, por meio disso, identificar as expectativas e necessidades que os motivam a buscar esses programas e como esses aspectos estão sendo satisfeitos. Para isso, utilizaram-se questionários semi-estruturados, respondidos pelos alunos de Administração na disciplina Estágio Supervisionado. Após a mensuração quantitativa dos dados, optou-se pela análise de conteúdo, que deu suporte à investigação qualitativa dos comentários pessoais dos discentes. Os

  4. SP mountain data analysis

    Science.gov (United States)

    Rawson, R. F.; Hamilton, R. E.; Liskow, C. L.; Dias, A. R.; Jackson, P. L.

    1981-01-01

    An analysis of synthetic aperture radar data of SP Mountain was undertaken to demonstrate the use of digital image processing techniques to aid in geologic interpretation of SAR data. These data were collected with the ERIM X- and L-band airborne SAR using like- and cross-polarizations. The resulting signal films were used to produce computer compatible tapes, from which four-channel imagery was generated. Slant range-to-ground range and range-azimuth-scale corrections were made in order to facilitate image registration; intensity corrections were also made. Manual interpretation of the imagery showed that L-band represented the geology of the area better than X-band. Several differences between the various images were also noted. Further digital analysis of the corrected data was done for enhancement purposes. This analysis included application of an MSS differencing routine and development of a routine for removal of relief displacement. It was found that accurate registration of the SAR channels is critical to the effectiveness of the differencing routine. Use of the relief displacement algorithm on the SP Mountain data demonstrated the feasibility of the technique.

  5. Chroococcidiopsis sp. strain AAB1, a new model from the Atacama desert for the understanding of extreme UV tolerance in an astrobiological context

    International Nuclear Information System (INIS)

    Azua-Bustos, A.; Arenas, C.; Paulino-Lima, I G.; Galante, D.

    2012-01-01

    Full text: The Atacama Desert in northern Chile is the driest and oldest desert on Earth. In a recently published report [Azua-Bustos, 2011] we showed that along its Coastal Range, fog can support hypolithic colonization rates of 80From these hypolithic communities we were able to obtain a previously unknown strain of Chroococcidiopsis which we characterized by morphological and molecular means. Due to the extreme tolerance of cyanobacteria of this genus to UV, and since the Atacama Desert has constantly high UV radiation levels all year long, we propose this strain as a pertinent model for understanding the limits UV tolerance for life as we know it. We have measured the viability of the isolate by using the DEAD/LIVE BacLight kit which allows the detection of dead cells by measuring the loss of integrity of the plasma membrane, and found that it remains almost unchanged with control cultures when desiccated. In addition, desiccated samples readily start new cultures. Transmission electron microscopy (TEM) of desiccated samples show no evident changes compared with controls. Pigments extracts from desiccated samples show a decrease in photosynthetic pigments like Chlorophyll-a, measured by fluorescence spectra and by tissue layer chromatography. Desiccated samples also synthesize sucrose, an intracellular compatible solute known to play a role in desiccation tolerance. As desiccation and extreme UV tolerance are thought to share similar metabolic routes [Rebecchi, 2007], we expect that our isolate (as suggested by preliminary experiments performed with our strain at LNLS in 2010) should be extremely tolerant to UV radiation. Future work include exposition of monolayers of our strain using the VUV line, and the determination of its comparative tolerance levels with a Chroococcidiopsis strain (N76) isolated from the Mojave Desert which we also have in culture. The experiments will consist of different exposition times in order to achieve increasing UV accumulation

  6. Developmental changes and gender effects on motivational constructs based on the expectancy-value model in Czech and United States students regarding learning of science, mathematics, and other subjects

    Science.gov (United States)

    Yang, Eun-Mi

    This study employed American and Czech student samples to investigate the motivational constructs used in Eccles and Wigfield's (1983) expectancy-value model. To predict achievement behavior, the model specifies relationships among expectancy for-success and task value, task-specific self-concept, perception of task-difficulty, perceptions of social environment, and interpretations and attributions for past events in relation to the social world. Czech and American students (n = 1,145) in grades 4--12 were the participants in this study. The causal relationships among the constructs were tested to investigate structural similarities and differences in the models for both countries. This study also explored developmental changes, gender, and national differences in the students' motivational beliefs for these motivational constructs: Expectancy for Success, Intrinsic Interest Value, Task-specific Self-concept, Perception of Task-difficulty, and Perceived Vocational Gender Dominance for science, mathematics, and other school subjects. The findings indicated that, for both countries, with respect to changes over grade level, compared to the younger students, the older students showed lower motivational beliefs for most subject areas except reading. However, the Czech students in grades 6--8 showed more positive motivational beliefs in life science and social studies than did the Czech students in other grade levels. In comparing genders, the male students exhibited more positive motivational beliefs in physical science than did the female students, and female students showed more positive motivational beliefs in reading than did the male students. For life science, the Czech female students rated Intrinsic Interest Value and Task-specific Self-concept higher than did their peer male students. The American students' motivational beliefs in reading were more positive than were Czech students', and the Czech students held more positive motivational beliefs in life

  7. Prior expectations facilitate metacognition for perceptual decision.

    Science.gov (United States)

    Sherman, M T; Seth, A K; Barrett, A B; Kanai, R

    2015-09-01

    The influential framework of 'predictive processing' suggests that prior probabilistic expectations influence, or even constitute, perceptual contents. This notion is evidenced by the facilitation of low-level perceptual processing by expectations. However, whether expectations can facilitate high-level components of perception remains unclear. We addressed this question by considering the influence of expectations on perceptual metacognition. To isolate the effects of expectation from those of attention we used a novel factorial design: expectation was manipulated by changing the probability that a Gabor target would be presented; attention was manipulated by instructing participants to perform or ignore a concurrent visual search task. We found that, independently of attention, metacognition improved when yes/no responses were congruent with expectations of target presence/absence. Results were modeled under a novel Bayesian signal detection theoretic framework which integrates bottom-up signal propagation with top-down influences, to provide a unified description of the mechanisms underlying perceptual decision and metacognition. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Economic Loan Loss Provision and Expected Loss

    Directory of Open Access Journals (Sweden)

    Stefan Hlawatsch

    2010-10-01

    Full Text Available The intention of a loan loss provision is the anticipation of the loan's expected losses by adjusting the book value of the loan. Furthermore, this loan loss provision has to be compared to the expected loss according to Basel II and, in the case of a difference, liable equity has to be adjusted. This however assumes that the loan loss provision and the expected loss are based on a similar economic rationale, which is only valid conditionally in current loan loss provisioning methods according to IFRS. Therefore, differences between loan loss provisions and expected losses should only result from different approaches regarding the parameter estimation within each model and not due to different assumptions regarding the outcome of the model. The provisioning and accounting model developed in this paper overcomes the before-mentioned shortcomings and is consistent with an economic rationale of expected losses. Additionally, this model is based on a close-to-market valuation of the loan that is in favor of the basic idea of IFRS. Suggestions for changes in current accounting and capital requirement rules are provided.

  9. A strategy for representing the effects of convective momentum transport in multiscale models: Evaluation using a new superparameterized version of the Weather Research and Forecast model (SP-WRF)

    Science.gov (United States)

    Tulich, S. N.

    2015-06-01

    This paper describes a general method for the treatment of convective momentum transport (CMT) in large-scale dynamical solvers that use a cyclic, two-dimensional (2-D) cloud-resolving model (CRM) as a "superparameterization" of convective-system-scale processes. The approach is similar in concept to traditional parameterizations of CMT, but with the distinction that both the scalar transport and diagnostic pressure gradient force are calculated using information provided by the 2-D CRM. No assumptions are therefore made concerning the role of convection-induced pressure gradient forces in producing up or down-gradient CMT. The proposed method is evaluated using a new superparameterized version of the Weather Research and Forecast model (SP-WRF) that is described herein for the first time. Results show that the net effect of the formulation is to modestly reduce the overall strength of the large-scale circulation, via "cumulus friction." This statement holds true for idealized simulations of two types of mesoscale convective systems, a squall line, and a tropical cyclone, in addition to real-world global simulations of seasonal (1 June to 31 August) climate. In the case of the latter, inclusion of the formulation is found to improve the depiction of key synoptic modes of tropical wave variability, in addition to some aspects of the simulated time-mean climate. The choice of CRM orientation is also found to importantly affect the simulated time-mean climate, apparently due to changes in the explicit representation of wide-spread shallow convective regions.

  10. Expectations on Track? High School Tracking and Adolescent Educational Expectations

    DEFF Research Database (Denmark)

    Karlson, Kristian Bernt

    2015-01-01

    This paper examines the role of adaptation in expectation formation processes by analyzing how educational tracking in high schools affects adolescents' educational expectations. I argue that adolescents view track placement as a signal about their academic abilities and respond to it in terms...... of modifying their educational expectations. Applying a difference-in-differences approach to the National Educational Longitudinal Study of 1988, I find that being placed in an advanced or honors class in high school positively affects adolescents’ expectations, particularly if placement is consistent across...... subjects and if placement contradicts tracking experiences in middle school. My findings support the hypothesis that adolescents adapt their educational expectations to ability signals sent by schools....

  11. Interest rate rules and macroeconomic stability under heterogeneous expectations

    NARCIS (Netherlands)

    Anufriev, M.; Assenza, T.; Hommes, C.; Massaro, D.

    2009-01-01

    The recent macroeconomic literature stresses the importance of managing heterogeneous expectations in the formulation of monetary policy. We use a stylized macro model of Howitt (1992) to investigate inflation dynamics under alternative interest rate rules when agents have heterogeneous expectations

  12. An evaluation of inflation expectations in Turkey

    Directory of Open Access Journals (Sweden)

    Barış Soybilgen

    2017-03-01

    Full Text Available Expectations of inflation play a critical role in the process of price setting in the market. Central banks closely follow developments in inflation expectations to implement a successful monetary policy. The Central Bank of the Republic of Turkey (CBRT conducts a survey of experts and decision makers in the financial and real sectors to reveal market expectations and predictions of current and future inflation. The survey is conducted every month. This paper examines the accuracy of these survey predictions using forecast evaluation techniques. We focus on both point and sign accuracy of the predictions. Although point predictions from CBRT surveys are compared with those of autoregressive models, sign predictions are evaluated on their value to a user. We also test the predictions for bias. Unlike the empirical evidence from other economies, our results show that autoregressive models outperform most of inflation expectations in forecasting inflation. This indicates that inflation expectations have poor point forecast accuracies. However, we show that sign predictions for all inflation expectations have value to a user.

  13. Components of attention modulated by temporal expectation

    DEFF Research Database (Denmark)

    Sørensen, Thomas Alrik; Vangkilde, Signe Allerup; Bundesen, Claus

    2015-01-01

    By varying the probabilities that a stimulus would appear at particular times after the presentation of a cue and modeling the data by the theory of visual attention (Bundesen, 1990), Vangkilde, Coull, and Bundesen (2012) provided evidence that the speed of encoding a singly presented stimulus...... letter into visual short-term memory (VSTM) is modulated by the observer’s temporal expectations. We extended the investigation from single-stimulus recognition to whole report (Experiment 1) and partial report (Experiment 2). Cue–stimulus foreperiods were distributed geometrically using time steps...... of 500 ms. In high expectancy conditions, the probability that the stimulus would appear on the next time step, given that it had not yet appeared, was high, whereas in low expectancy conditions, the probability was low. The speed of encoding the stimuli into VSTM was higher in the high expectancy...

  14. Interaction of calcitonin gene related peptide (CGRP) and substance P (SP) in human skin.

    Science.gov (United States)

    Schlereth, Tanja; Schukraft, Jonas; Krämer-Best, Heidrun H; Geber, Christian; Ackermann, Tatiana; Birklein, Frank

    2016-10-01

    Calcitonin gene related peptide (CGRP) and substance P (SP) are neuropeptides that are simultaneously released from nociceptive C-fibers. CGRP is a potent vasodilator, inducing a long-lasting increase in superficial skin blood flow, whereas SP induces only a brief vasodilation but a significant plasma extravasation. CGRP and SP may play important roles in the pathophysiology of various pain states but little is known about their interaction. Different concentrations of SP (ranging from 10 -5 M to 10 -9 M) were applied to the volar forearm of 24 healthy subjects via dermal microdialysis. SP was applied either alone or in combination with CGRP10 -9 M and CGRP 10 -6 M. As expected, SP induced a transient increase in skin blood flow that decayed shortly after application. This transient blood flow peak was blunted with co-application of CGRP 10 -9 M and inhibited with co-application of CGRP10 -6 M. SP alone induced plasma protein extravasation (PPE). However, when CGRP10 -6 M was added, the PPE significantly increased. Our results demonstrate a complex interaction of the neuropeptides CGRP and SP. CGRP10 -6 M prevented SP-induced early vasodilation but augmented SP-induced PPE. These interactions might explain why vascular symptoms in chronic pain can differ strikingly between individuals. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Estudo da erosão na microbacia do Ceveiro (Piracicaba, SP: I - Estimativa das taxas de perda de solo e estudo de sensibilidade dos fatores do modelo EUPS Erosion study in the Ceveiro Watershed (Piracicaba, SP.: I - Estimation o soil loss rates and sensitivity factor analysis of the USLE model

    Directory of Open Access Journals (Sweden)

    Mara de Andrade Marinho Weill

    2008-04-01

    Full Text Available A erosão acelerada do solo constitui um sério problema global de degradação de terras agrícolas. Por ser a pesquisa de erosão comumente cara e morosa, a utilização de modelos permite estimar a perda de solo em localidades e condições não diretamente representadas nos estudos. O objetivo deste trabalho foi estimar a expectativa de erosão do solo em uma área intensivamente cultivada com cana-de-açúcar no município de Piracicaba (SP, como subsídio ao diagnóstico do uso atual das terras visando ao controle do processo. O trabalho foi realizado em ambiente de sistema de informação geográfica aplicando a equação universal de perda de solo (EUPS. Especificamente pretendeu-se estudar a influência dos fatores K (erodibilidade do solo, LS (topográfico, C (uso e manejo da cultura e P (práticas de controle da erosão nas estimativas de perda de solo. Os resultados obtidos mostraram que o processo de degradação dos solos por erosão acelerada é intenso em cerca de dois terços da área avaliada, ocupados principalmente com cana-de-açúcar. Nessas áreas, a perda média estimada de 58 Mg ha-1 ano-1 equivale a cerca de quatro vezes o limite superior da tolerância média indicada. Nas áreas remanescentes, ocupadas com mata, vegetação ciliar, reflorestamento e pastagens, as taxas estimadas de perda de solo são baixas, em torno de 2 Mg ha-1 ano-1 , abaixo dos valores de tolerância. O estudo de sensibilidade dos fatores do modelo revelou que, para uma mesma condição climática (fator R constante, os fatores C e P (cobertura e manejo da cultura e práticas de controle da erosão definiram a ordem de grandeza das perdas, em unidades, dezenas ou centenas de Mg ha-1 ano-1 . Para uma mesma categoria de uso da terra (fatores C e P constantes, o fator LS foi o que explicou a maior parte da variação observada. Os resultados obtidos a partir de uma simulação mostraram que a influência do fator K (erodibilidade do solo nas

  16. SP-100 Test Site

    International Nuclear Information System (INIS)

    Cox, C.M.; Mahaffey, M.K.; Miller, W.C.

    1988-01-01

    Preparatory activities are well under way at Hanford to convert the 309 Containment Building and its associated service wing to a 2.5 MWt nuclear test facility for the SP-100 Ground Engineering System (GES) test. Preliminary design is complete, encompassing facility modifications, a secondary heat transport system, a large vacuum system to enclose the high temperature reactor, a test assembly cell and handling system, control and data processing systems, and safety and auxiliary systems. The design makes extensive use of existing equipment to minimize technical risk and cost. Refurbishment of this equipment is 75% complete. The facility has been cleared of obstructing equipment from its earlier reactor test. Current activities are focusing on definitive design and preparation of the Preliminary Safety Analysis Report (PSAR) aimed at procurement and construction approvals and schedules to achieve reactor criticality by January 1992. 6 refs

  17. Expectation-based intelligent control

    International Nuclear Information System (INIS)

    Zak, Michail

    2006-01-01

    New dynamics paradigms-negative diffusion and terminal attractors-are introduced to control noise and chaos. The applied control forces are composed of expectations governed by the associated Fokker-Planck and Liouville equations. The approach is expanded to a general concept of intelligent control via expectations. Relevance to control in livings is emphasized and illustrated by neural nets with mirror neurons

  18. Decomposing change in life expectancy

    DEFF Research Database (Denmark)

    Vaupel, James W.; Canudas Romo, Vladimir

    2003-01-01

    We extend Nathan Keyfitz's research on continuous change in life expectancy over time by presenting and proving a new formula for decomposing such change. The formula separates change in life expectancy over time into two terms. The first term captures the general effect of reduction in death rates...... in Sweden and Japan....

  19. Sibling Status Effects: Adult Expectations.

    Science.gov (United States)

    Baskett, Linda Musun

    1985-01-01

    This study attempted to determine what expectations or beliefs adults might hold about a child based on his or her sibling status alone. Ratings on 50 adjective pairs for each of three sibling status types, only, oldest, and youngest child, were assessed in relation to adult expectations, birth order, and parental status of rater. (Author/DST)

  20. Carbon sp chains in graphene nanoholes

    International Nuclear Information System (INIS)

    Castelli, Ivano E; Ferri, Nicola; Onida, Giovanni; Manini, Nicola

    2012-01-01

    Nowadays sp carbon chains terminated by graphene or graphitic-like carbon are synthesized routinely in several nanotech labs. We propose an ab initio study of such carbon-only materials, by computing their structure and stability, as well as their electronic, vibrational and magnetic properties. We adopt a fair compromise of microscopic realism with a certain level of idealization in the model configurations, and predict a number of properties susceptible to comparison with experiment. (paper)

  1. Carbon sp chains in graphene nanoholes

    Science.gov (United States)

    Castelli, Ivano E.; Ferri, Nicola; Onida, Giovanni; Manini, Nicola

    2012-03-01

    Nowadays sp carbon chains terminated by graphene or graphitic-like carbon are synthesized routinely in several nanotech labs. We propose an ab initio study of such carbon-only materials, by computing their structure and stability, as well as their electronic, vibrational and magnetic properties. We adopt a fair compromise of microscopic realism with a certain level of idealization in the model configurations, and predict a number of properties susceptible to comparison with experiment.

  2. Neural correlates of rhythmic expectancy

    Directory of Open Access Journals (Sweden)

    Theodore P. Zanto

    2006-01-01

    Full Text Available Temporal expectancy is thought to play a fundamental role in the perception of rhythm. This review summarizes recent studies that investigated rhythmic expectancy by recording neuroelectric activity with high temporal resolution during the presentation of rhythmic patterns. Prior event-related brain potential (ERP studies have uncovered auditory evoked responses that reflect detection of onsets, offsets, sustains,and abrupt changes in acoustic properties such as frequency, intensity, and spectrum, in addition to indexing higher-order processes such as auditory sensory memory and the violation of expectancy. In our studies of rhythmic expectancy, we measured emitted responses - a type of ERP that occurs when an expected event is omitted from a regular series of stimulus events - in simple rhythms with temporal structures typical of music. Our observations suggest that middle-latency gamma band (20-60 Hz activity (GBA plays an essential role in auditory rhythm processing. Evoked (phase-locked GBA occurs in the presence of physically presented auditory events and reflects the degree of accent. Induced (non-phase-locked GBA reflects temporally precise expectancies for strongly and weakly accented events in sound patterns. Thus far, these findings support theories of rhythm perception that posit temporal expectancies generated by active neural processes.

  3. Fertility expectations and residential mobility in Britain

    Directory of Open Access Journals (Sweden)

    John Ermisch

    2016-12-01

    Full Text Available Background: It is plausible that people take into account anticipated changes in family size in choosing where to live. But estimation of the impact of anticipated events on current transitions in an event history framework is challenging because expectations must be measured in some way and, like indicators of past childbearing, expected future childbearing may be endogenous with respect to housing decisions. Objective: The objective of the study is to estimate how expected changes in family size affect residential movement in Great Britain in a way which addresses these challenges. Methods: We use longitudinal data from a mature 18-wave panel survey, the British Household Panel Survey, which incorporates a direct measure of fertility expectations. The statistical methods allow for the potential endogeneity of expectations in our estimation and testing framework. Results: We produce evidence consistent with the idea that past childbearing mainly affects residential mobility through expectations of future childbearing, not directly through the number of children in the household. But there is heterogeneity in response. In particular, fertility expectations have a much greater effect on mobility among women who face lower costs of mobility, such as private tenants. Conclusions: Our estimates indicate that expecting to have a(nother child in the future increases the probability of moving by about 0.036 on average, relative to an average mobility rate of 0.14 per annum in our sample. Contribution: Our contribution is to incorporate anticipation of future events into an empirical model of residential mobility. We also shed light on how childbearing affects mobility.

  4. Cardinal Coordinate Independence for Expected Utility

    NARCIS (Netherlands)

    Wakker, P.

    1984-01-01

    A representation theorem for binary relations on (Re)n is derived. It is interpreted in the context of decision making under uncertainty. There we consider the existence of a subjective expected utility model to represent a preference relation of a person on the set of bets for money on a finite

  5. Cardinal Coordinate Independence for Expected Utility

    NARCIS (Netherlands)

    P.P. Wakker (Peter)

    1984-01-01

    textabstractA representation theorem for binary relations on n is derived. It is interpreted in the context of decision making under uncertainty. There we consider the existence of a subjective expected utility model to represent a preference relation of a person on the set of bets for money on a

  6. Photosynthetic versatility in the genome of Geitlerinema sp. PCC 9228 (formerly Oscillatoria limnetica ‘Solar Lake’, a model anoxygenic photosynthetic cyanobacterium

    Directory of Open Access Journals (Sweden)

    Sharon L Grim

    2016-10-01

    Full Text Available Anoxygenic cyanobacteria that use sulfide as the electron donor for photosynthesis are a potentially influential but poorly constrained force on Earth’s biogeochemistry. Their versatile metabolism may have boosted primary production and nitrogen cycling in euxinic coastal margins in the Proterozoic. In addition, they represent a biological mechanism for limiting the accumulation of atmospheric oxygen, especially before the Great Oxidation Event and in the low-oxygen conditions of the Proterozoic. In this study, we describe the draft genome sequence of Geitlerinema sp. PCC 9228, formerly Oscillatoria limnetica ‘Solar Lake’, a mat-forming diazotrophic cyanobacterium that can switch between oxygenic photosynthesis and sulfide-based anoxygenic photosynthesis. Geitlerinema possesses three variants of psbA, which encodes protein D1, a core component of the photosystem II reaction center. Phylogenetic analyses indicate that one variant is closely affiliated with cyanobacterial psbA genes that code for a D1 protein used for oxygen-sensitive processes. Another version is phylogenetically similar to cyanobacterial psbA genes that encode D1 proteins used under microaerobic conditions, and the third variant may be cued to high light and/or elevated oxygen concentrations. Geitlerinema has the canonical gene for sulfide quinone reductase (SQR used in cyanobacterial anoxygenic photosynthesis and a putative transcriptional regulatory gene in the same operon. Another operon with a second, distinct sqr and regulatory gene is present, and is phylogenetically related to sqr genes used for high sulfide concentrations. The genome has a comprehensive nif gene suite for nitrogen fixation, supporting previous observations of nitrogenase activity. Geitlerinema possesses a bidirectional hydrogenase rather than the uptake hydrogenase typically used by cyanobacteria in diazotrophy. Overall, the genome sequence of Geitlerinema sp. PCC 9228 highlights potential

  7. Photosynthetic Versatility in the Genome of Geitlerinema sp. PCC 9228 (Formerly Oscillatoria limnetica ‘Solar Lake’), a Model Anoxygenic Photosynthetic Cyanobacterium

    Science.gov (United States)

    Grim, Sharon L.; Dick, Gregory J.

    2016-01-01

    Anoxygenic cyanobacteria that use sulfide as the electron donor for photosynthesis are a potentially influential but poorly constrained force on Earth’s biogeochemistry. Their versatile metabolism may have boosted primary production and nitrogen cycling in euxinic coastal margins in the Proterozoic. In addition, they represent a biological mechanism for limiting the accumulation of atmospheric oxygen, especially before the Great Oxidation Event and in the low-oxygen conditions of the Proterozoic. In this study, we describe the draft genome sequence of Geitlerinema sp. PCC 9228, formerly Oscillatoria limnetica ‘Solar Lake’, a mat-forming diazotrophic cyanobacterium that can switch between oxygenic photosynthesis and sulfide-based anoxygenic photosynthesis (AP). Geitlerinema possesses three variants of psbA, which encodes protein D1, a core component of the photosystem II reaction center. Phylogenetic analyses indicate that one variant is closely affiliated with cyanobacterial psbA genes that code for a D1 protein used for oxygen-sensitive processes. Another version is phylogenetically similar to cyanobacterial psbA genes that encode D1 proteins used under microaerobic conditions, and the third variant may be cued to high light and/or elevated oxygen concentrations. Geitlerinema has the canonical gene for sulfide quinone reductase (SQR) used in cyanobacterial AP and a putative transcriptional regulatory gene in the same operon. Another operon with a second, distinct sqr and regulatory gene is present, and is phylogenetically related to sqr genes used for high sulfide concentrations. The genome has a comprehensive nif gene suite for nitrogen fixation, supporting previous observations of nitrogenase activity. Geitlerinema possesses a bidirectional hydrogenase rather than the uptake hydrogenase typically used by cyanobacteria in diazotrophy. Overall, the genome sequence of Geitlerinema sp. PCC 9228 highlights potential cyanobacterial strategies to cope with

  8. Dialysis centers - what to expect

    Science.gov (United States)

    ... kidneys - dialysis centers; Dialysis - what to expect; Renal replacement therapy - dialysis centers; End-stage renal disease - dialysis ... to a tube that connects to the dialysis machine. Your blood will flow through the tube, into ...

  9. Life expectancy in bipolar disorder

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Vradi, Eleni; Andersen, Per Kragh

    2015-01-01

    OBJECTIVE: Life expectancy in patients with bipolar disorder has been reported to be decreased by 11 to 20 years. These calculations are based on data for individuals at the age of 15 years. However, this may be misleading for patients with bipolar disorder in general as most patients have a later...... onset of illness. The aim of the present study was to calculate the remaining life expectancy for patients of different ages with a diagnosis of bipolar disorder. METHODS: Using nationwide registers of all inpatient and outpatient contacts to all psychiatric hospitals in Denmark from 1970 to 2012 we...... remaining life expectancy in bipolar disorder and that of the general population decreased with age, indicating that patients with bipolar disorder start losing life-years during early and mid-adulthood. CONCLUSIONS: Life expectancy in bipolar disorder is decreased substantially, but less so than previously...

  10. FastStats: Life Expectancy

    Science.gov (United States)

    ... What's this? Submit What's this? Submit Button NCHS Home ... expectancy at birth, at 65, and 75 years of age by sex, race and Hispanic origin Health, United States 2016, table 15 [PDF – 9.8 MB] Life ...

  11. Physical activity extends life expectancy

    Science.gov (United States)

    Leisure-time physical activity is associated with longer life expectancy, even at relatively low levels of activity and regardless of body weight, according to a study by a team of researchers led by the NCI.

  12. Subjective expected utility without preferences

    OpenAIRE

    Bouyssou , Denis; Marchant , Thierry

    2011-01-01

    This paper proposes a theory of subjective expected utility based on primitives only involving the fact that an act can be judged either "attractive" or "unattractive". We give conditions implying that there are a utility function on the set of consequences and a probability distribution on the set of states such that attractive acts have a subjective expected utility above some threshold. The numerical representation that is obtained has strong uniqueness properties.

  13. Managing heterogeneous and unanchored expectations: a monetary policy analysis

    NARCIS (Netherlands)

    Hommes, C.; Lustenhouwer, J.

    2016-01-01

    We study monetary policy in a New Keynesian model with heterogeneity in expectations. Agents may choose from a continuum of forecasting rules and adjust their expectations based on relative past performance. The extent to which expectations are anchored to the fundamentals of the economy turns out

  14. Bradysia sp. em morangueiro Bradysia sp. in strawberry

    Directory of Open Access Journals (Sweden)

    Bernadete Radin

    2009-04-01

    Full Text Available No trabalho, relatam-se os primeiros registros de Bradysia sp. (Insecta: Diptera: Sciaridae em morangueiro (Fragaria x ananassa Duch., cultivado no Município de Eldorado do Sul, RS. O cultivo foi realizado em sacolas com três metros de comprimento, preenchidas com substrato composto de casca de arroz e turfa, dispostas horizontalmente sobre bancadas de madeira, em ambiente protegido. A presença de Bradysia sp. foi observada na segunda quinzena de agosto de 2005. Neste trabalho, estão descritos os sintomas apresentados no morangueiro pela praga, prováveis conseqüências sobre o aparecimento de doenças e uma breve descrição morfológica da Bradysia sp., adulto e fase larval.This paper describes the first record of Bradysia sp. (Insecta; Diptera; Sciaridae in strawberry (Fragaria x ananassa, cultivated in the city of Eldorado do Sul, RS, Brazil. Strawberry was planted in plastic bags filled with a mixture of burnt rice hulls and peat and cultivated in a greenhouse. The presence of Bradysia sp was noticed in the second fortnight of August, 2005. The symptoms in strawberry and the probable consequences in terms of disease arising were described in the present study, as well as the morphological characterization of Bradysia sp. and its illustrations.

  15. Yersinia pekkanenii sp. nov.

    Science.gov (United States)

    Murros-Kontiainen, Anna; Johansson, Per; Niskanen, Taina; Fredriksson-Ahomaa, Maria; Korkeala, Hannu; Björkroth, Johanna

    2011-10-01

    The taxonomic position of three strains from water, soil and lettuce samples was studied by using a polyphasic taxonomic approach. The strains were reported to lack the virulence-encoding genes inv and virF in a previous study. Controversially, API 20 E and some other phenotypic tests suggested that the strains belong to Yersinia pseudotuberculosis, which prompted this polyphasic taxonomic study. In both the phylogenetic analyses of four housekeeping genes (glnA, gyrB, recA and HSP60) and numerical analyses of HindIII and EcoRI ribopatterns, the strains formed a separate group within the genus Yersinia. Analysis of the 16S rRNA gene sequences showed that the strains were related to Yersinia aldovae and Yersinia mollaretii, but DNA-DNA hybridization analysis differentiated them from these species. Based on the results of the phylogenetic and DNA-DNA hybridization analyses, a novel species, Yersinia pekkanenii sp. nov., is proposed. The type strain is ÅYV7.1KOH2(T) ( = DSM 22769(T)  = LMG 25369(T)).

  16. Biosorption characteristics of copper (II), chromium (III), nickel (II), and lead (II) from aqueous solutions by Chara sp. and Cladophora sp.

    Science.gov (United States)

    Elmaci, Ayşe; Yonar, Taner; Ozengin, Nihan

    2007-09-01

    The aim of this research was to expose individual removals of copper, chromium, nickel, and lead from aqueous solutions via biosorption using nonliving algae species, Chara sp. and Cladophora sp. Optimum pH values for biosorption of copper (II), chromium (III), nickel (II), and lead (II) from aqueous solutions were determined to be 6, 7, 7, and 3 for Cladophora sp. and 5, 3, 5, and 4 for Chara sp. respectively. Maximum adsorption capacities of Chara sp. [10.54 for chromium (III) and 61.72 for lead (II)] and Cladophora sp. [6.59 for chromium (III) and 16.75 and 23.25 for lead (II)] for chromium (III) and lead (II) are similar. On the other hand, copper (II) and nickel (II) biosorption capacity of Cladophora sp. [14.28 for copper (II) and 16.75 for nickel (II)] is greater than Chara sp. [6.506 for copper (II) and 11.76 for nickel (II)]. Significantly high correlation coefficients indicated for the Langmuir adsorption isotherm models can be used to describe the equilibrium behavior of copper, chromium, nickel, and lead adsorption onto Cladophora sp. and Chara sp.

  17. The SP Theory of Intelligence: Benefits and Applications

    Directory of Open Access Journals (Sweden)

    J. Gerard Wolff

    2013-12-01

    Full Text Available This article describes existing and expected benefits of the SP theory ofintelligence, and some potential applications. The theory aims to simplify and integrate ideasacross artificial intelligence, mainstream computing, and human perception and cognition,with information compression as a unifying theme. It combines conceptual simplicitywith descriptive and explanatory power across several areas of computing and cognition.In the SP machine—an expression of the SP theory which is currently realized in theform of a computer model—there is potential for an overall simplification of computingsystems, including software. The SP theory promises deeper insights and better solutions inseveral areas of application including, most notably, unsupervised learning, natural languageprocessing, autonomous robots, computer vision, intelligent databases, software engineering,information compression, medical diagnosis and big data. There is also potential inareas such as the semantic web, bioinformatics, structuring of documents, the detection ofcomputer viruses, data fusion, new kinds of computer, and the development of scientifictheories. The theory promises seamless integration of structures and functions within andbetween different areas of application. The potential value, worldwide, of these benefits andapplications is at least $190 billion each year. Further development would be facilitatedby the creation of a high-parallel, open-source version of the SP machine, available toresearchers everywhere.

  18. Antimicrobial peptides from Capsicum sp.

    African Journals Online (AJOL)

    ajl yemi

    2011-12-30

    Dec 30, 2011 ... Key words: Antimicrobial peptides, Capsicum sp, Capsicum chinense, chili pepper, agronomical options, ..... of this human activity is resumed by the simple phrase: produce .... It will be interesting to scale the AMPs extraction.

  19. Linking surfactant protein SP-D and IL-13

    DEFF Research Database (Denmark)

    Qaseem, Asif S; Sonar, Sanchaita; Mahajan, Lakshna

    2012-01-01

    of allergen-IgE interaction, histamine release by sensitised mast cells, downregulation of specific IgE production, suppression of pulmonary and peripheral eosinophilia, inhibition of mechanisms that cause airway remodelling, and induction of apoptosis in sensitised eosinophils. SP-D can also shift helper T......Surfactant protein D (SP-D) is an innate immune molecule that plays a protective role against lung infection, allergy, asthma and inflammation. In vivo experiments with murine models have shown that SP-D can protect against allergic challenge via a range of mechanisms including inhibition...... cell polarisation following in vivo allergenic challenge, from pathogenic Th2 to a protective Th1 cytokine response. Interestingly, SP-D gene deficient (-/-) mice show an IL-13 over-expressing phenotype. IL-13 has been shown to be involved in the development of asthma. Transgenic mice over...

  20. Policing Challenged and People’s Expectations

    Directory of Open Access Journals (Sweden)

    Thakur Mohan Shrestha

    2015-04-01

    Full Text Available Peace, security, rule of law, and sustainable development are driving principles in a democratic notion of developing country like Nepal. "3Is': Injustice, Insecurity and Imbalance have been reflecting in the post transitional Nepal. The study came with the objectives of investigating the peoples' perceptions on the adaptation of policing, the challenges and expectation. The information was collected from 1111(N respondents all over the country from different ways of life, applying mixed method questionnaire survey and interview. The research show the need of system based policing like 'intelligence-led'; 'police public partnership', and 'proactive' respectively. The influence of politicization, political instability, external influence, lack of role model leadership, open border, rampant corruption, nepotism-favoritism, lack of research are the major challenges in the security organizations. Furthermore, most educated and high profile personalities have less interest to encourage their generation in police services. People are expecting proficient and accountable police forces. Keywords: Policing, Challenges, People's Expectation

  1. Longitudinal analyses of adoptive parents' expectations and depressive symptoms.

    Science.gov (United States)

    Foli, Karen J; Lim, Eunjung; South, Susan C

    2017-12-01

    Grounded in a theoretical model specific to adoptive parents, we examined the relationship between parental expectations and depressive symptoms across time. Assessments of 129 adoptive parents of 64 children were performed at three time points before and after placement of an adopted child with the family: 4-6 weeks pre-placement and 4-6 weeks and 5-6 months post-placement. Expectations were assessed in four dimensions: expectations of self as parents, of the child, of family and friends, and of society. Depressive symptoms were assessed with the Center for Epidemiologic Studies-Depression scale. Associations between parental expectations and depressive symptoms were analyzed, and longitudinal multilevel modeling was conducted to explore influences on expectations over time. Parental expectations changed from pre- to post-placement. With the exception of expectations of self as parent, adoptive parents' pre-adoption expectations were affirmed in the post-adoption time periods. In each expectation dimension, higher affirmation of expectations was correlated with decreased depressive symptoms before and after placement of a child. While parental expectations are not unique to adoptive parents, the essence and characteristics of certain expectations are unique to these parents. When working with adoptive parents, nurses who care for families should assess expectations both pre- and post-placement with awareness of their relationship to depressive symptoms. © 2017 Wiley Periodicals, Inc.

  2. Protective Effects of Surfactant Protein D (SP-D) Treatment in 1,3-β-glucan-modulated Allergic Inflammation

    DEFF Research Database (Denmark)

    Fakih, Dalia; Pilecki, Bartosz; Schlosser, Anders

    2015-01-01

    SP-D is a pulmonary collectin important in lung immunity. SP-D-deficient mice (Sftpd(-/-)) are reported to be susceptible to ovalbumin (OVA)- and fungal allergen-induced pulmonary inflammation, while treatment with exogenous SP-D has therapeutic effects in such disease models. β-glucans are a div...

  3. Changing mortality and average cohort life expectancy

    Directory of Open Access Journals (Sweden)

    Robert Schoen

    2005-10-01

    Full Text Available Period life expectancy varies with changes in mortality, and should not be confused with the life expectancy of those alive during that period. Given past and likely future mortality changes, a recent debate has arisen on the usefulness of the period life expectancy as the leading measure of survivorship. An alternative aggregate measure of period mortality which has been seen as less sensitive to period changes, the cross-sectional average length of life (CAL has been proposed as an alternative, but has received only limited empirical or analytical examination. Here, we introduce a new measure, the average cohort life expectancy (ACLE, to provide a precise measure of the average length of life of cohorts alive at a given time. To compare the performance of ACLE with CAL and with period and cohort life expectancy, we first use population models with changing mortality. Then the four aggregate measures of mortality are calculated for England and Wales, Norway, and Switzerland for the years 1880 to 2000. CAL is found to be sensitive to past and present changes in death rates. ACLE requires the most data, but gives the best representation of the survivorship of cohorts present at a given time.

  4. Broken Expectations: Violation of Expectancies, Not Novelty, Captures Auditory Attention

    Science.gov (United States)

    Vachon, Francois; Hughes, Robert W.; Jones, Dylan M.

    2012-01-01

    The role of memory in behavioral distraction by auditory attentional capture was investigated: We examined whether capture is a product of the novelty of the capturing event (i.e., the absence of a recent memory for the event) or its violation of learned expectancies on the basis of a memory for an event structure. Attentional capture--indicated…

  5. Transcription profiling of the model cyanobacterium Synechococcus sp. strain PCC 7002 by NextGen (SOLiD™ Sequencing of cDNA

    Directory of Open Access Journals (Sweden)

    Marcus eLudwig

    2011-03-01

    Full Text Available The genome of the unicellular, euryhaline cyanobacterium Synechococcus sp. PCC 7002 encodes about 3200 proteins. Transcripts were detected for nearly all annotated open reading frames by a global transcriptomic analysis by Next-Generation (SOLiDTM sequencing of cDNA. In the cDNA samples sequenced, ~90% of the mapped sequences were derived from the 16S and 23S ribosomal RNAs and ~10% of the sequences were derived from mRNAs. In cells grown photoautotrophically under standard conditions (38 °C, 1% (v/v CO2 in air, 250 µmol photons m-2 s-1, the highest transcript levels (up to 2% of the total mRNA for the most abundantly transcribed genes (e. g., cpcAB, psbA, psaA were generally derived from genes encoding structural components of the photosynthetic apparatus. High light exposure for one hour caused changes in transcript levels for genes encoding proteins of the photosynthetic apparatus, Type-1 NADH dehydrogenase complex and ATP synthase, whereas dark incubation for one hour resulted in a global decrease in transcript levels for photosynthesis-related genes and an increase in transcript levels for genes involved in carbohydrate degradation. Transcript levels for pyruvate kinase and the pyruvate dehydrogenase complex decreased sharply in cells incubated in the dark. Under dark anoxic (fermentative conditions, transcript changes indicated a global decrease in transcripts for respiratory proteins and suggested that cells employ an alternative phosphoenolpyruvate degradation pathway via phosphoenolpyruvate synthase (ppsA and the pyruvate:ferredoxin oxidoreductase (nifJ. Finally, the data suggested that an apparent operon involved in tetrapyrrole biosynthesis and fatty acid desaturation, acsF2-ho2-hemN2-desF, may be regulated by oxygen concentration.

  6. Consumer's inflation expectations in Brazil

    Directory of Open Access Journals (Sweden)

    Fernando Ormonde Teixeira

    Full Text Available Abstract This paper investigates what are the main components of consumer's inflation expectations. We combine the FGV's Consumer Survey with the indices of inflation (IPCA and government regulated prices, professional forecasts disclosed in the Focus report, and media data which we crawl from one of the biggest and most important Brazilian newspapers, Folha de São Paulo, to determine what factors are responsible for and improve consumer's forecast accuracy. We found gender, age and city of residence as major elements when analyzing micro-data. Aggregate data shows the past inflation as an important trigger in the formation of consumers' expectations and professional forecasts as negligible. Moreover, the media plays a significant role, accounting not only for the expectations' formation but for a better understanding of actual inflation as well.

  7. Test expectancy affects metacomprehension accuracy.

    Science.gov (United States)

    Thiede, Keith W; Wiley, Jennifer; Griffin, Thomas D

    2011-06-01

    Theory suggests that the accuracy of metacognitive monitoring is affected by the cues used to judge learning. Researchers have improved monitoring accuracy by directing attention to more appropriate cues; however, this is the first study to more directly point students to more appropriate cues using instructions regarding tests and practice tests. The purpose of the present study was to examine whether the accuracy metacognitive monitoring was affected by the nature of the test expected. Students (N= 59) were randomly assigned to one of two test expectancy groups (memory vs. inference). Then after reading texts, judging learning, completed both memory and inference tests. Test performance and monitoring accuracy were superior when students received the kind of test they had been led to expect rather than the unexpected test. Tests influence students' perceptions of what constitutes learning. Our findings suggest that this could affect how students prepare for tests and how they monitoring their own learning. ©2010 The British Psychological Society.

  8. Expectations for a scientific collaboratory

    DEFF Research Database (Denmark)

    Sonnenwald, Diane H.

    2003-01-01

    In the past decade, a number of scientific collaboratories have emerged, yet adoption of scientific collaboratories remains limited. Meeting expectations is one factor that influences adoption of innovations, including scientific collaboratories. This paper investigates expectations scientists have...... with respect to scientific collaboratories. Interviews were conducted with 17 scientists who work in a variety of settings and have a range of experience conducting and managing scientific research. Results indicate that scientists expect a collaboratory to: support their strategic plans; facilitate management...... of the scientific process; have a positive or neutral impact on scientific outcomes; provide advantages and disadvantages for scientific task execution; and provide personal conveniences when collaborating across distances. These results both confirm existing knowledge and raise new issues for the design...

  9. Expectations and voluntary attrition in nursing students.

    Science.gov (United States)

    O'Donnell, Hugh

    2011-01-01

    This paper presents a series of findings generated during a larger study which aimed to develop a theoretical understanding of the reasons why nursing students voluntarily leave pre-registration nursing programmes. In this study, significant incongruence was found to exist between student expectations of pre-registration nursing programmes and the reality of these programmes following entry. The resulting dissonance was identified as an important factor in student decisions to voluntarily withdraw. A single case study design was selected to explore the causes of voluntary attrition in nursing students within a School of Nursing and Midwifery. The study population was obtained through purposeful sampling and consisted of 15 students who had previously voluntarily withdrawn from pre-registration nursing programmes. A semi-structured interview method was used to collect data from study participants. The interview schedule developed for use in the study reflected the key components of the conceptual model of higher education (HE) student attrition (Tinto, 1975, 1987, 1993). All interviews were tape recorded to facilitate later transcription. The Cyclical or Interactive Model of Qualitative Research (Miles and Huberman, 1994) was used to analyse data collected from study participants. This paper describes the unrealistic range of expectations which nursing students have of nursing, the information sources and experiences which inform student expectations and how ambiguous expectations contributed to voluntarily attrition. Copyright © 2010 Elsevier Ltd. All rights reserved.

  10. Career Expectations of Accounting Students

    Science.gov (United States)

    Elam, Dennis; Mendez, Francis

    2010-01-01

    The demographic make-up of accounting students is dramatically changing. This study sets out to measure how well the profession is ready to accommodate what may be very different needs and expectations of this new generation of students. Non-traditional students are becoming more and more of a tradition in the current college classroom.…

  11. Primary expectations of secondary metabolites

    Science.gov (United States)

    My program examines the plant secondary metabolites (i.e. phenolics) important for human health, and which impart the organoleptic properties that are quality indicators for fresh and processed foods. Consumer expectations such as appearance, taste, or texture influence their purchasing decisions; a...

  12. Privacy Expectations in Online Contexts

    Science.gov (United States)

    Pure, Rebekah Abigail

    2013-01-01

    Advances in digital networked communication technology over the last two decades have brought the issue of personal privacy into sharper focus within contemporary public discourse. In this dissertation, I explain the Fourth Amendment and the role that privacy expectations play in the constitutional protection of personal privacy generally, and…

  13. When feeling bad is expected to be good: emotion regulation and outcome expectancies in social conflicts.

    Science.gov (United States)

    Tamir, Maya; Ford, Brett Q

    2012-08-01

    According to the instrumental approach to emotion regulation, people may want to experience even unpleasant emotions to attain instrumental benefits. Building on value-expectancy models of self-regulation, we tested whether people want to feel bad in certain contexts specifically because they expect such feelings to be useful to them. In two studies, participants were more likely to try to increase their anger before a negotiation when motivated to confront (vs. collaborate with) a negotiation partner. Participants motivated to confront (vs. collaborate with) their partner expected anger to be more useful to them, and this expectation in turn, led them to try to increase their anger before negotiating. The subsequent experience of anger, following random assignment to emotion inductions (Study 1) or engagement in self-selected emotion regulation activities (Study 2), led participants to be more successful at getting others to concede to their demands, demonstrating that emotional preferences have important pragmatic implications.

  14. Ethical issues and societal expectations

    International Nuclear Information System (INIS)

    Metlay, D.

    2010-01-01

    Daniel Metlay (NWTRB) declared that institutions had always recognised an ethical obligation to manage high- level radioactive waste in unprecedented ways. This obligation has not only endured, but has become more explicit and multidimensional and it now subsumed under a more general rubric of 'societal expectations'. D. Metlay directed attention toward the proceedings of previous RWMC-RF workshop ', which contains five essays, authored by Kjell Andersson, Andrew Blowers, Carl-Reinhold Braakenhielm, Francois Dermange, and Patricia Fleming, that are relevant to the question of ethical issues and societal expectations. D. Metlay observed that 'societal expectations' are hard to define and thus very hard to measure. They may vary considerably with time and from country to country. As an illustration he referred to an inquiry performed by a task group 30 years ago in a document entitled 'Proposed Goals for Radioactive Waste Management' (NUREG-0300) on behalf of the U.S. Nuclear Regulatory Commission. Conclusions from D. Metlay are that, for the most part, societal expectations in the United States appear to be quite stable over a period of more than 30 years. In two areas, however, there are clear differences in emphasis between expectations articulated in the last few years and those recorded in 1978. (1) While then there was emphasis on the operational reliability of organisations and institutions. In particular, much care was taken to discuss the inherent limitations on bureaucratic error-correction in the future. The focus is nowadays more on bureaucratic behaviours associated with carrying out decision-making processes in the present. (2) While there is current emphasis on the importance of trust, transparency, and accountability, the NRC document may cast some doubt on the reliability of a stepwise decision-making process. In the domain of radioactive waste management, error signals are notoriously unclear, and strong disagreements over objectives and value trade

  15. The construction of normal expectations

    DEFF Research Database (Denmark)

    Quitzau, Maj-Britt; Røpke, Inge

    2008-01-01

    The gradual upward changes of standards in normal everyday life have significant environmental implications, and it is therefore important to study how these changes come about. The intention of the article is to analyze the social construction of normal expectations through a case study. The case...... concerns the present boom in bathroom renovations in Denmark, which offers an excellent opportunity to study the interplay between a wide variety of consumption drivers and social changes pointing toward long-term changes of normal expectations regarding bathroom standards. The study is problemoriented...... and transdisciplinary and draws on a wide range of sociological, anthropological, and economic theories. The empirical basis comprises a combination of statistics, a review of magazine and media coverage, visits to exhibitions, and qualitative interviews. A variety of consumption drivers are identified. Among...

  16. FRANCHISE EXPECTATIONS: CASE OF KAZAKHSTAN

    OpenAIRE

    Raissa Kaziyeva

    2014-01-01

    The purpose of the article is to provide a critical review of franchising development in Kazakhstan by focusing on the relationship between the franchisor and the franchisee. We have conducted extensive research and communicated with lots of potential and existing Kazakhstani franchisors and franchisees, operating since 2003. Our findings show that the process of signing franchising agreements is quite challenging in Kazakhstan.  Thorough investigation of the differences between expectations ...

  17. Life Expectancy of Brazilian Neurosurgeons.

    Science.gov (United States)

    Botelho, Ricardo Vieira; Jardim Miranda, Bárbara Cristina; Nishikuni, Koshiro; Waisberg, Jaques

    2018-06-01

    Life expectancy (LE) refers to the number of years that an individual is expected to survive. Emphasis is frequently placed on the relationship between LE and the conditions under which a population lives, but fewer studies have investigated the relationship between stress factors associated with specific professions and their effects on LE. The aim of this study is to evaluate Brazilian neurosurgeons' life expectancies (BNLEs) and compare them with those of physicians (both Brazilian and foreign) from other fields, as well as with Brazilian nondoctors. The Brazilian Society of Neurosurgery death registry was used to obtain data that compared LEs from non-neurosurgeon physicians, as described in the national and international literature. BNLEs were also compared with the LEs of Brazilian citizens. Fifty-one neurosurgeons died between 2009 and 2016. All were males. The mean age at death was 68.31 ± 17.71 years. Among all-cause mortality, the breakdown was 20% cardiovascular diseases, 39% malignancies, 10% external factors, 6% gastrointestinal disorders, 12% neurologic illnesses, and 14% unknown causes. BNLE was shorter than LE of male Brazilian citizens. LE was similar among neurosurgeons and other doctors but shorter compared with Brazilian citizens. Further research is needed to provide data that can add to and confirm these results. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Seroprevalencia de Leptospira sp., Rickettsia sp. Ehrlichia sp. en trabajadores rurales del departamento de Sucre, Colombia Seroprevalence of Leptospira sp., Rickettsia sp. and Ehrlichia sp. in rural workers of Sucre, Colombia

    Directory of Open Access Journals (Sweden)

    Rodrigo Ríos

    2008-06-01

    Full Text Available Objective. Determinar la seroprevalencia de Leptospira sp., Rickettsia sp. y Ehrlichia sp. en trabajadores de áreas rurales del departamento de Sucre. Material y métodos. Se realizó un estudio escriptivo, prospectivo, de corte transversal, que pretendió determinar la seroprevalencia e Leptospira sp., Rickettsia sp. y Ehrlichia sp. en 90 trabajadores de áreas rurales del departamento de Sucre. Se estableció la presencia de anticuerpos séricos anti-IgM específicos anti-Leptospira por la técnica de ELISA indirecta. Para la determinación de Rickettsia sp. y Ehrlichia sp. se uso la técnica de inmunofluorescencia indirecta. Resultados. La población evaluada estaba compuesta por 27 (30% ordeñadores, 21 (23% jornaleros, 18 (20% profesionales del campo y 24 (27% que realizaban otras actividades. Ventidós (24% muestras resultaron positivas en alguna de las pruebas. De éstas, 12 (13,3% fueron positivas para Leptospira sp., 7 (7,8% para Rickettsia sp. y 3 (3,3% ara Ehrlichia sp. Conclusión. Este fue el primer estudio que se llevó a cabo en el departamento de Sucre y permitió demostrar que existe una prevalencia importante de Leptospira p.,Rickettsia sp. y Ehrlichia sp.. Los factores de riesgo ocupacional fueron factores determinantes en la seropositividad.Objective. To determine the seroprevalence of Leptospira sp., Rickettsia sp. and Ehrlichia sp. in agricultural workers of Sucre. Methods. A descriptive prospective cross-sectional study was conducted in ninety rural workers of Sucre. Presence of serum antibodies anti-IgM specific anti-Leptospira by indirect ELISA was established. For the determination of Rickettsia and Ehrlichia indirect inmunoflorescence was used. Results.The population was composed by 27 (30% milkers, 21 (23% day workers, 18 farm professionals (20% and 24 (26% workers in others activities. A total of 22 (24% samples were positive to some test. Twelve (13.3% were positive to Leptospira sp., seven (7.8% to Rickettsia sp

  19. Analytical models for development of high performance metal targets irradiated in IPEN-CNEN/SP Cyclone 30 and Cyclone 18 cyclotrons

    International Nuclear Information System (INIS)

    Oliveira, Henrique Barcellos de

    2009-01-01

    Analytical models were developed that describe the basic elements for metal targets irradiation in cyclotrons. Important parameters such as maximum beam current value and thermal power deposited on target were obtained and compared with practical situations. In an unprecedented way, were determined analytically the features found in intense thermal transient situations, when high protons concentrations in a small region of the beam cause intense temperature gradients in small regions of the target. Comparing with results found in the literature showed that the developed models are satisfactory, in view of all limitations of the proposed model. (author)

  20. Researches with the 'Fertexpert' model concerning the relationships between the efficiency indexes of the fertilizers usage in optimal economic rates and the agrochemical indexes of the soil and expected yields

    International Nuclear Information System (INIS)

    Budoi, G.; Berca, M.; Borlan, Z.; Gavriluta, I.; Soare, M.; Danuso, F.; Bireescu, L.

    1999-01-01

    The 'Fertexpert' model allows undertaking researches concerning the variation of efficiency indexes for fertilizers usage in the case of many crops depending on the content of available soil nutrients (the values of soil agrochemical indexes - IA) and on the expected yield, R s , when fertilization are applied in optimal economic rates, DOE. The physical efficiency indexes calculated and researched are the following: the total physical yield increase, SFR (kg/ha), the specific average yield increase, SSp (kg/kg N, P 2 O 5 or K 2 O), the specific consumption of active substance (a.s.) from fertilizer, CSp (kg a.s./1 kg average yield increase). The economic efficiency indexes computed are: the total profit, in monetary units/ha, the specific profit, in monetary units/l monetary unit spent with fertilization, PSp, and in monetary units/kg a.s., PSpsa. The model also allows the study of DOE variation depending on R s and IA. Starting from the made calculations, there can be drown up specific graphics that can then be used in practice and for research purposes to. Refs. 6 (author)

  1. SP-100 reactor cell activation

    International Nuclear Information System (INIS)

    Wilcox, A.D.

    1991-09-01

    There are plans to test the SP-100 space reactor for 2 yr in the test facility shown in Figure 1. The vacuum vessel will be in the reactor experiment (RX) cell surrounded by an inert gas atmosphere. It is proposed that the reactor test cell could contain removable-water- shielding tanks to reduce the residual activation dose rates in the test cell after the tests are completed. This reduction will allow the facility to be considered for other uses after the SP-100 tests are completed. The radiation dose rates in the test cell were calculated for several configurations of water-shielding tanks to help evaluate this concept

  2. Performance expectations in the new configuration

    International Nuclear Information System (INIS)

    Lallia, P.P.; Rebut, P.-H.

    1989-01-01

    The pumped divertor to be installed in JET should allow a control of the particles and of the impurities. The new hardware required into the vacuum vessel leads to a reduction of the plasma cross section. While a plasma current of 6 MA should still be possible, this will affect the confinement of the plasma. The JET performances in the New Configuration are estimated from the critical electron temperature gradient model by using a 1-D transport code. It has been shown in the past that this model gives a rather satisfactory description of the JET discharges. However it does not address the particle transport and density profiles have to be imposed. By comparison with numerical simulations of the present JET configuration, it is shown that the reduction in plasma size should be more than balanced by the lower impurity concentration expected to result from the divertor. In terms of thermonuclear Q th , a doubling is found relatively to the expectations in the present configuration (≅ .9 against .45). On the other hand Q th should be lowered to .3 if the impurity control is inefficient. In this case as presently observed in JET it is expected that no steady state will be achieved. (author)

  3. Shapes of leaves with parallel venation. Modelling of the Epipactis sp. (Orchidaceae leaves with the help of a system of coupled elastic beams

    Directory of Open Access Journals (Sweden)

    Anna Jakubska-Busse

    2016-06-01

    Full Text Available Static properties of leaves with parallel venation, with particular emphasis on the genus EpipactisZinn, 1757 (Orchidaceae, Neottieae have been modelled with coupled quasi-parallel elastic “beams.” The non-linear theory of strongly bended beams have been employed. The resulting boundary-value problem has been solved numerically with the help of the finite-difference method. Possible dislocations resulting in additional Dirac-delta like forces have been take into account. Morphological similarity of the model and real leaves has been obtained. In particular, the concentrated forces have been shown to cause undulation in the leaves.

  4. The Large Hadron Collider - Expectations and Reality

    International Nuclear Information System (INIS)

    Litov, Leandar

    2010-01-01

    The Large Hadron Colider (LHC) is the biggest particle accelerator in the world designed to accelerate protons and heavy ions to extremely high energies. The four detector complexes installed around the beam crossing points, are expected to shed light on some of the more fundamental questions about our Universe ever asked--what are the fundamental constituents of the matter, what are the forces controlling their behavior and what is the structure of the space-time. In November, the LHC will be restarted and the detector complexes are expected to commence taking the first collision data. The physical motivation for the LHC experimental program and some open questions of the Standard Model of strong and electroweak interactions (SM) are discussed. Special attention is paid to observation of signatures for physics beyond the SM and the discovery potential of the LHC experiments is commented. One of the two general-purpose detector complexes (CMS, the Compact Muon Solenoid) is described briefly.

  5. Managing Media: Segmenting Media Through Consumer Expectancies

    Directory of Open Access Journals (Sweden)

    Matt Eastin

    2014-04-01

    Full Text Available It has long been understood that consumers are motivated to media differently. However, given the lack of comparative model analysis, this assumption is without empirical validation, and thus, the orientation of segmentation from a media management perspective is without motivational grounds. Thus, evolving the literature on media consumption, the current study develops and compares models of media segmentation within the context of use. From this study, six models of media expectancies were constructed so that motivational differences between media (i.e., local and national newspapers, network and cable television, radio, and Internet could be observed. Utilizing higher order statistical analyses the data indicates differences across a model comparison approach for media motivations. Furthermore, these differences vary across numerous demographic factors. Results afford theoretical advancement within the literature of consumer media consumption as well as provide media planners’ insight into consumer choices.

  6. Modeling the Relationship between Safety Climate and Safety Performance in a Developing Construction Industry: A Cross-Cultural Validation Study.

    Science.gov (United States)

    Zahoor, Hafiz; Chan, Albert P C; Utama, Wahyudi P; Gao, Ran; Zafar, Irfan

    2017-03-28

    This study attempts to validate a safety performance (SP) measurement model in the cross-cultural setting of a developing country. In addition, it highlights the variations in investigating the relationship between safety climate (SC) factors and SP indicators. The data were collected from forty under-construction multi-storey building projects in Pakistan. Based on the results of exploratory factor analysis, a SP measurement model was hypothesized. It was tested and validated by conducting confirmatory factor analysis on calibration and validation sub-samples respectively. The study confirmed the significant positive impact of SC on safety compliance and safety participation , and negative impact on number of self-reported accidents/injuries . However, number of near-misses could not be retained in the final SP model because it attained a lower standardized path coefficient value. Moreover, instead of safety participation , safety compliance established a stronger impact on SP. The study uncovered safety enforcement and promotion as a novel SC factor, whereas safety rules and work practices was identified as the most neglected factor. The study contributed to the body of knowledge by unveiling the deviations in existing dimensions of SC and SP. The refined model is expected to concisely measure the SP in the Pakistani construction industry, however, caution must be exercised while generalizing the study results to other developing countries.

  7. Harm beliefs and coping expectancies in youth with specific phobias.

    Science.gov (United States)

    Ollendick, Thomas H; Öst, Lars-Göran; Ryan, Sarah M; Capriola, Nicole N; Reuterskiöld, Lena

    2017-04-01

    Catastrophic beliefs and lowered coping expectancies are often present in individuals with specific phobias (SPs). The current study examined these beliefs and expectancies in 251 youth who received One Session Treatment for one of the three most common types of SP in youth (animals, natural environment, and situational). We compared the children's subjective beliefs to objective ratings of the likelihood of occurrence and the dangerousness of the feared events. Results revealed pre-treatment differences in the youths' beliefs across phobia types and age. Specifically, children with animal phobias rated their beliefs as more likely to occur than did children with environmental and situational phobias. In addition, older children rated their beliefs as more dangerous than younger children. However, regardless of phobia type or child age, the beliefs improved following treatment. Changes in catastrophic beliefs and coping expectancies were related to changes in clinical severity following treatment but not 6-months following treatment. Moreover, at pre-treatment, children viewed their beliefs as significantly more catastrophic and likely to occur than did independent coders of these beliefs; however, these differences were no longer evident following treatment. Clinical implications are discussed, highlighting how changes in beliefs and expectancies might be associated with treatment outcomes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Comparative analysis of tree classification models for detecting fusarium oxysporum f. sp cubense (TR4) based on multi soil sensor parameters

    Science.gov (United States)

    Estuar, Maria Regina Justina; Victorino, John Noel; Coronel, Andrei; Co, Jerelyn; Tiausas, Francis; Señires, Chiara Veronica

    2017-09-01

    Use of wireless sensor networks and smartphone integration design to monitor environmental parameters surrounding plantations is made possible because of readily available and affordable sensors. Providing low cost monitoring devices would be beneficial, especially to small farm owners, in a developing country like the Philippines, where agriculture covers a significant amount of the labor market. This study discusses the integration of wireless soil sensor devices and smartphones to create an application that will use multidimensional analysis to detect the presence or absence of plant disease. Specifically, soil sensors are designed to collect soil quality parameters in a sink node from which the smartphone collects data from via Bluetooth. Given these, there is a need to develop a classification model on the mobile phone that will report infection status of a soil. Though tree classification is the most appropriate approach for continuous parameter-based datasets, there is a need to determine whether tree models will result to coherent results or not. Soil sensor data that resides on the phone is modeled using several variations of decision tree, namely: decision tree (DT), best-fit (BF) decision tree, functional tree (FT), Naive Bayes (NB) decision tree, J48, J48graft and LAD tree, where decision tree approaches the problem by considering all sensor nodes as one. Results show that there are significant differences among soil sensor parameters indicating that there are variances in scores between the infected and uninfected sites. Furthermore, analysis of variance in accuracy, recall, precision and F1 measure scores from tree classification models homogeneity among NBTree, J48graft and J48 tree classification models.

  9. Regulatory Expectations for Safety Culture

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Su Jin; Oh, Jang Jin; Choi, Young Sung [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2014-05-15

    The oversight of licensee's safety culture becomes an important issue that attracts great public and political concerns recently in Korea. Beginning from the intended violation of rules, a series of corruptions, documents forgery and disclosure of wrong-doings made the public think that the whole mindset of nuclear workers has been inadequate. Thus, they are demanding that safety culture shall be improved and that regulatory body shall play more roles and responsibilities for the improvements and oversight for them. This paper introduces, as an effort of regulatory side, recent changes in the role of regulators in safety culture, regulatory expectations on the desired status of licensee's safety culture, the pilot inspection program for safety culture and research activity for the development of oversight system. After the Fukushima accident in Japan 2011, many critics has searched for cultural factors that caused the unacceptable negligence pervaded in Japan nuclear society and the renewed emphasis has been placed on rebuilding safety culture by operators, regulators, and relevant institutions globally. Significant progress has been made in how to approach safety culture and led to a new perspective different from the existing normative assessment method both in operators and regulatory side. Regulatory expectations and oversight of them are based on such a new holistic concept for human, organizational and cultural elements to maintain and strengthen the integrity of defense in depth and consequently nuclear safety.

  10. Expectation values in quantum gravity

    International Nuclear Information System (INIS)

    Jordan, R.D.

    1986-01-01

    The purpose of this dissertation is to develop new methods for calculating expectation values of field operators, in situations where particle creation is important. The goal is to apply these techniques to quantum gravity, to see if the initial singularity in the universe might be avoided in the quantum theory. Standard effective action theory is modified to produce effective field equations satisfied by the expectation value of the field in an in state, as opposed to the usual in-out amplitude. Diagrammatic rules are found for calculation of the new field equations, and are used to show that the equations are real and causal up to two loop order. The theory also provides a simple check of unitarity, which is carried out, again up to two loops. Just as the standard effective field equations can be derived by analytic continuation from a theory defined in Euclidean space, so can the modified equations be obtained from a modified contour rotation of the Euclidean theory. This result is used to prove a recent conjecture which yields a simple rule for finding the real, causal equations. The new formalism is applied to two gravitational systems. First, the stability of flat space time is studied by finding the equation satisfied by small perturbations of Minkowski space

  11. Regulatory Expectations for Safety Culture

    International Nuclear Information System (INIS)

    Jung, Su Jin; Oh, Jang Jin; Choi, Young Sung

    2014-01-01

    The oversight of licensee's safety culture becomes an important issue that attracts great public and political concerns recently in Korea. Beginning from the intended violation of rules, a series of corruptions, documents forgery and disclosure of wrong-doings made the public think that the whole mindset of nuclear workers has been inadequate. Thus, they are demanding that safety culture shall be improved and that regulatory body shall play more roles and responsibilities for the improvements and oversight for them. This paper introduces, as an effort of regulatory side, recent changes in the role of regulators in safety culture, regulatory expectations on the desired status of licensee's safety culture, the pilot inspection program for safety culture and research activity for the development of oversight system. After the Fukushima accident in Japan 2011, many critics has searched for cultural factors that caused the unacceptable negligence pervaded in Japan nuclear society and the renewed emphasis has been placed on rebuilding safety culture by operators, regulators, and relevant institutions globally. Significant progress has been made in how to approach safety culture and led to a new perspective different from the existing normative assessment method both in operators and regulatory side. Regulatory expectations and oversight of them are based on such a new holistic concept for human, organizational and cultural elements to maintain and strengthen the integrity of defense in depth and consequently nuclear safety

  12. An Empirical Study of Audit Expectation Gap in Hungary

    OpenAIRE

    Judit Füredi-Fülöp

    2015-01-01

    The audit expectation gap has preoccupied the finance and accounting profession for a long time. Considerable research has been conducted into this issue and attempts have been made to provide an accurate definition of the audit expectation gap, model this concept and assess the possibilities of its narrowing. Also, a number of studies investigate whether there is an audit expectation gap in several researched regions. The objectives of empirical studies on the structure and nature of the aud...

  13. Complete genome sequence of N2-fixing model strain Klebsiella sp. nov. M5al, which produces plant cell wall-degrading enzymes and siderophores

    Directory of Open Access Journals (Sweden)

    Zhili Yu

    2018-03-01

    Full Text Available The bacterial strain M5al is a model strain for studying the molecular genetics of N2-fixation and molecular engineering of microbial production of platform chemicals 1,3-propanediol and 2,3-butanediol. Here, we present the complete genome sequence of the strain M5al, which belongs to a novel species closely related to Klebsiella michiganensis. M5al secretes plant cell wall-degrading enzymes and colonizes rice roots but does not cause soft rot disease. M5al also produces siderophores and contains the gene clusters for synthesis and transport of yersiniabactin which is a critical virulence factor for Klebsiella pathogens in causing human disease. We propose that the model strain M5al can be genetically modified to study bacterial N2-fixation in association with non-legume plants and production of 1,3-propanediol and 2,3-butanediol through degradation of plant cell wall biomass.

  14. Comparison of a static and a dynamic in vitro model to estimate the bioaccessibility of As, Cd, Pb and Hg from food reference materials Fucus sp. (IAEA-140/TM) and Lobster hepatopancreas (TORT-2)

    Energy Technology Data Exchange (ETDEWEB)

    Torres-Escribano, Silvia [Instituto de Agroquimica y Tecnologia de Alimentos (IATA-CSIC), Apdo. 73, 46100, Burjassot, Valencia (Spain); Denis, Sylvain; Blanquet-Diot, Stephanie [Clermont Universite, Universite d' Auvergne, Centre de Recherche en Nutrition Humaine Auvergne, ERT 18, Conception ingenierie et developpement de l' aliment et du medicament, BP 10448, F-63000 Clermont-Ferrand (France); Calatayud, Marta [Instituto de Agroquimica y Tecnologia de Alimentos (IATA-CSIC), Apdo. 73, 46100, Burjassot, Valencia (Spain); Barrios, Laura [Departamento de Informatica Cientifica (SGAI-CSIC), C/ Pinar 19, 28006 Madrid (Spain); Velez, Dinoraz, E-mail: deni@iata.csic.es [Instituto de Agroquimica y Tecnologia de Alimentos (IATA-CSIC), Apdo. 73, 46100, Burjassot, Valencia (Spain); Alric, Monique [Clermont Universite, Universite d' Auvergne, Centre de Recherche en Nutrition Humaine Auvergne, ERT 18, Conception ingenierie et developpement de l' aliment et du medicament, BP 10448, F-63000 Clermont-Ferrand (France); Montoro, Rosa [Instituto de Agroquimica y Tecnologia de Alimentos (IATA-CSIC), Apdo. 73, 46100, Burjassot, Valencia (Spain)

    2011-01-01

    Bioaccessibility, the fraction of an element solubilized during gastrointestinal digestion and available for absorption, is a factor that should be considered when evaluating the health risk of contaminants from food. Static and dynamic models that mimic human physiological conditions have been used to evaluate bioaccessibility. This preliminary study compares the bioaccessibility of arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg) in two food certified reference materials (CRMs) (seaweed: Fucus sp., IAEA-140/TM; Lobster hepatopancreas: TORT-2), using two in vitro gastrointestinal digestion methods: a static method (SM) and a dynamic multicompartment method (TIM-1). There are significant differences (p < 0.05) between the bioaccessible values of As, Cd, Pb and Hg obtained by SM and TIM-1 in the two CRMs. The specific form in which the elements studied are present in the CRM may help to explain the bioaccessibility values obtained. - Research Highlights: {yields}Data are reported for As, Cd, Pb and Hg bioaccessibility from food CRMs. {yields}The static and TIM-1 methods give significantly different bioaccessibility values. {yields}The possible influence of speciation on bioaccessibility is discussed. {yields}To improve bioaccessibility quality data, food reference materials are needed.

  15. Comparison of a static and a dynamic in vitro model to estimate the bioaccessibility of As, Cd, Pb and Hg from food reference materials Fucus sp. (IAEA-140/TM) and Lobster hepatopancreas (TORT-2)

    International Nuclear Information System (INIS)

    Torres-Escribano, Silvia; Denis, Sylvain; Blanquet-Diot, Stephanie; Calatayud, Marta; Barrios, Laura; Velez, Dinoraz; Alric, Monique; Montoro, Rosa

    2011-01-01

    Bioaccessibility, the fraction of an element solubilized during gastrointestinal digestion and available for absorption, is a factor that should be considered when evaluating the health risk of contaminants from food. Static and dynamic models that mimic human physiological conditions have been used to evaluate bioaccessibility. This preliminary study compares the bioaccessibility of arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg) in two food certified reference materials (CRMs) (seaweed: Fucus sp., IAEA-140/TM; Lobster hepatopancreas: TORT-2), using two in vitro gastrointestinal digestion methods: a static method (SM) and a dynamic multicompartment method (TIM-1). There are significant differences (p < 0.05) between the bioaccessible values of As, Cd, Pb and Hg obtained by SM and TIM-1 in the two CRMs. The specific form in which the elements studied are present in the CRM may help to explain the bioaccessibility values obtained. - Research Highlights: →Data are reported for As, Cd, Pb and Hg bioaccessibility from food CRMs. →The static and TIM-1 methods give significantly different bioaccessibility values. →The possible influence of speciation on bioaccessibility is discussed. →To improve bioaccessibility quality data, food reference materials are needed.

  16. Shapes of leaves with parallel venation. Modelling of the Epipactis sp. (Orchidaceae) leaves with the help of a system of coupled elastic beams

    OpenAIRE

    Jakubska-Busse, Anna; Janowicz, Maciej; Ochnio, Luiza; Jackowska-Zduniak, Beata

    2016-01-01

    Static properties of leaves with parallel venation, with particular emphasis on the genus EpipactisZinn, 1757 (Orchidaceae, Neottieae) have been modelled with coupled quasi-parallel elastic “beams.” The non-linear theory of strongly bended beams have been employed. The resulting boundary-value problem has been solved numerically with the help of the finite-difference method. Possible dislocations resulting in additional Dirac-delta like forces have been take into account. Morphological simila...

  17. Flux Balance Analysis of Cyanobacterial Metabolism.The Metabolic Network of Synechocystis sp. PCC 6803

    Czech Academy of Sciences Publication Activity Database

    Knoop, H.; Gründel, M.; Zilliges, Y.; Lehmann, R.; Hoffmann, S.; Lockau, W.; Steuer, Ralf

    2013-01-01

    Roč. 9, č. 6 (2013), e1003081-e1003081 ISSN 1553-7358 R&D Projects: GA MŠk(CZ) EE2.3.20.0256 Institutional support: RVO:67179843 Keywords : SP STRAIN PCC-6803 * SP ATCC 51142 * photoautotrophic metabolism * anacystis-nidulans * reconstructions * pathway * plants * models * growth Subject RIV: EI - Biotechnology ; Bionics Impact factor: 4.829, year: 2013

  18. Beyond Expected Utility in the Economics of Health and Longevity

    OpenAIRE

    Cordoba, Juan Carlos; Ripoll, Marla

    2013-01-01

    We document various limitations of the expected utility model for the study of health and longevity. The model assumes individuals are indifferent between early and late resolution of uncertainty. This assumption gives rise to predictions regarding the economic value of life that are inconsistent with relevant evidence. For example, poor individuals would price life below the present value of foregone income or even negatively. We show that a non-expected utility model disentangling intertemp...

  19. When expectation confounds iconic memory.

    Science.gov (United States)

    Bachmann, Talis; Aru, Jaan

    2016-10-01

    In response to the methodological criticism (Bachmann & Aru, 2015) of the interpretation of their earlier experimental results (Mack, Erol, & Clarke, 2015) Mack, Erol, Clarke, and Bert (2016) presented new results that they interpret again in favor of the stance that an attention-free phenomenal iconic store does not exist. Here we once more question their conclusions. When their subjects were unexpectedly asked to report the letters instead of the post-cued circles in the 101th trial where letters were actually absent, they likely failed to see the empty display area because prior experience with letters in the preceding trials produced expectancy based illusory experience of letter-like objects. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Great expectations: large wind turbines

    International Nuclear Information System (INIS)

    De Vries, E.

    2001-01-01

    This article focuses on wind turbine product development, and traces the background to wind turbines from the first generation 1.5 MW machines in 1995-6, plans for the second generation 3-5 MW class turbines to meet the expected boom in offshore wind projects, to the anticipated installation of a 4.5 MW turbine, and offshore wind projects planned for 2000-2002. The switch by the market leader Vestas to variable speed operation in 2000, the new product development and marketing strategy taken by the German Pro + Pro consultancy in their design of a 1.5 MW variable speed pitch control concept, the possible limiting of the size of turbines due to logistical difficulties, opportunities offered by air ships for large turbines, and the commissioning of offshore wind farms are discussed. Details of some 2-5 MW offshore wind turbine design specifications are tabulated

  1. The SP Theory of Intelligence: An Overview

    Directory of Open Access Journals (Sweden)

    J Gerard Wolff

    2013-08-01

    Full Text Available This article is an overview of the SP theory of intelligence, which aims to simplify and integrate concepts across artificial intelligence, mainstream computing and human perception and cognition, with information compression as a unifying theme. It is conceived of as a brain-like system that receives "New" information and stores some or all of it in compressed form as "Old" information; and it is realised in the form of a computer model, a first version of the SP machine. The matching and unification of patterns and the concept of multiple alignment are central ideas. Using heuristic techniques, the system builds multiple alignments that are "good" in terms of information compression. For each multiple alignment, probabilities may be calculated for associated inferences. Unsupervised learning is done by deriving new structures from partial matches between patterns and via heuristic search for sets of structures that are "good" in terms of information compression. These are normally ones that people judge to be "natural", in accordance with the "DONSVIC" principle—the discovery of natural structures via information compression. The SP theory provides an interpretation for concepts and phenomena in several other areas, including "computing", aspects of mathematics and logic, the representation of knowledge, natural language processing, pattern recognition, several kinds of reasoning, information storage and retrieval, planning and problem solving, information compression, neuroscience and human perception and cognition. Examples include the parsing and production of language with discontinuous dependencies in syntax, pattern recognition at multiple levels of abstraction and its integration with part-whole relations, nonmonotonic reasoning and reasoning with default values, reasoning in Bayesian networks, including "explaining away", causal diagnosis, and the solving of a geometric analogy problem.

  2. Trading Stages: Life Expectancies in Structured Populations

    Science.gov (United States)

    Tuljapurkar, Shripad; Coulson, Tim; Horvitz, Carol

    2012-01-01

    Interest in stage-and age structured models has recently increased because they can describe quantitative traits such as size that are left out of age-only demography. Available methods for the analysis of effects of vital rates on lifespan in stage-structured models have not been widely applied because they are hard to use and interpret, and tools for age and stage structured populations are missing. We present easily interpretable expressions for the sensitivities and elasticities of life expectancy to vital rates in age-stage models, and illustrate their application with two biological examples. Much of our approach relies on trading of time and mortality risk in one stage for time and risk in others. Our approach contributes to the new framework of the study of age- and stage-structured biodemography. PMID:22664576

  3. Optimal provision of public goods with rank dependent expected utility

    OpenAIRE

    Eide, Erling

    2003-01-01

    In this paper the theory of rank-dependent expected utility (RDEU) is substituted for the theory of expected utility (EU) in a model of optimal provision of public goods. The substitution generalizes the Samuelson rule, previously modified to include deadweight loss and tax evasion loss.

  4. A Theory of False Cognitive Expectancies in Airline Pilots

    Science.gov (United States)

    Cortes, Antonio I.

    The Theory of False Cognitive Expectancies was developed by studying high reliability flight operations. Airline pilots depend extensively on cognitive expectancies to perceive, understand, and predict actions and events. Out of 1,363 incident reports submitted by airline pilots to the National Aeronautics and Space Administration Aviation Safety Reporting System over a year's time, 110 reports were found to contain evidence of 127 false cognitive expectancies in pilots. A comprehensive taxonomy was developed with six categories of interest. The dataset of 127 false expectancies was used to initially code tentative taxon values for each category. Intermediate coding through constant comparative analysis completed the taxonomy. The taxonomy was used for the advanced coding of chronological context-dependent visualizations of expectancy factors, known as strands, which depict the major factors in the creation and propagation of each expectancy. Strands were mapped into common networks to detect highly represented expectancy processes. Theoretical integration established 11 sources of false expectancies, the most common expectancy errors, and those conspicuous factors worthy of future study. The most prevalent source of false cognitive expectancies within the dataset was determined to be unconscious individual modeling based on past events. Integrative analyses also revealed relationships between expectancies and flight deck automation, unresolved discrepancies, and levels of situation awareness. Particularly noteworthy were the findings that false expectancies can combine in three possible permutations to diminish situation awareness and examples of how false expectancies can be unwittingly transmitted from one person to another. The theory resulting from this research can enhance the error coding process used during aircraft line oriented safety audits, lays the foundation for developing expectancy management training programs, and will allow researchers to proffer

  5. News on Inflation and the Epidemiology of Inflation Expectations

    DEFF Research Database (Denmark)

    Pfajfar, Damjan; Santoro, Emiliano

    2013-01-01

    This paper examines the nexus between news coverage on inflation and households’ inflation expectations. In doing so, we test the epidemiological foundations of the sticky information model (Carroll ). We use both aggregate and household-level data from the Survey Research Center at the University...... of Michigan. We highlight a fundamental disconnection among news on inflation, consumers’ frequency of expectation updating, and the accuracy of their expectations. Our evidence provides at best weak support to the epidemiological framework, as most of the consumers who update their expectations do not revise...

  6. Dietary intervention with green dwarf banana flour (Musa sp AAA) prevents intestinal inflammation in a trinitrobenzenesulfonic acid model of rat colitis.

    Science.gov (United States)

    Scarminio, Viviane; Fruet, Andrea C; Witaicenis, Aline; Rall, Vera L M; Di Stasi, Luiz C

    2012-03-01

    Dietary products are among the therapeutic approaches used to modify intestinal microflora and to promote protective effects during the intestinal inflammatory process. Because the banana plant is rich in resistant starch, which is used by colonic microbiota for the anaerobic production of the short-chain fatty acids that serve as a major fuel source for colonocytes: first, green dwarf banana flour produces protective effects on the intestinal inflammation acting as a prebiotic and, second, combination of this dietary supplementation with prednisolone presents synergistic effects. For this, we used the trinitrobenzenesulphonic acid (TNBS) model of rat colitis. Our results revealed that the protective effect produced by a combination of 10% green dwarf banana flour with prednisolone was more pronounced than those promoted by a single administration of prednisolone or a diet containing 10% or 20% banana flour. This beneficial effect was associated with an improvement in the colonic oxidative status because the banana flour diet prevented the glutathione depletion and inhibited myeloperoxidase activity and lipid peroxidation. In addition, the intestinal anti-inflammatory activity was associated with an inhibition of alkaline phosphatase activity, a reduction in macroscopic and microscopic scores, and an extension of the lesions. In conclusion, the dietary use of the green dwarf banana flour constitutes an important dietary supplement and complementary medicine product to prevention and treatment of human inflammatory bowel disease. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Raw materials from the region of Rio Claro - SP for the manufacture of ceramic coatings: technological characteristics and geological-technological modeling

    International Nuclear Information System (INIS)

    Cunha, R.A.; Roveri, C.D.; Maestrelli, S.C.

    2016-01-01

    The Santa Gertrudes Ceramic Polo (PCSG) is the largest national producer of ceramic tiles, located in east-central region of Sao Paulo, encompassing different cities. PCSG uses various clays as the main raw material from the Corumbatai Formation, which is inserted in the Sedimentary Basin of Parana, with more than 1.5 square kilometers. In this context, X-ray diffractograms of samples from different areas of PCSG were used for application of the cluster analysis. Aiming to group the samples in families and subsequently to seek the most representative for the complete analysis. Also, ceramic tests were made by the following methods: the green bulk density after pressing, flexural strength modulus for green. , tests were conducted after firing at 1070 °C and 1120 °C: apparent density after drying, flexural modulus; after firing: apparent density after firing, water absorption linear shrinkage sintering, apparent porosity, modulus of resistance to bending after burning. Further, from the georeferenced sample were created tables for industry in the area, to facilitate the identification of new sample by XRD. Furthermore, the 3D model of the region was developed from the interesting characteristics for ceramic use, using Micromine Mining Software, Enterprise Micromine. (author)

  8. Preventive and therapeutic administration of an indigenous Lactobacillus sp. strain against Proteus mirabilis ascending urinary tract infection in a mouse model.

    Science.gov (United States)

    Fraga, Martín; Scavone, Paola; Zunino, Pablo

    2005-07-01

    Probiotics are increasingly being considered as non-pharmaceutical and safe potential alternatives for the treatment and prevention of a variety of pathologies including urinary tract infections. These are the most common infections in medical practice and are frequently treated with antibiotics, which have generated an intense selective pressure over bacterial populations. Proteus mirabilis is a common cause of urinary tract infections in catheterised patients and people with abnormalities of the urinary tract. In this work we isolated, identified and characterised an indigenous Lactobacillus murinus strain (LbO2) from the vaginal tract of a female mouse. In vitro characterisation of LbO2 included acid and bile salts tolerance, growth in urine, adherence to uroepithelial cells and in vitro antimicrobial activity. The selected strain showed interesting properties, suitable for its use as a probiotic. The ability of LbO2 to prevent and even treat ascending P. mirabilis urinary tract infection was assessed using an experimental model in the mouse. Kidney and bladder P. mirabilis counts were significantly lower in mice preventively treated with the probiotic than in non-treated mice. When LbO2 was used for therapeutic treatment, bladder counts of treated mice were significantly lower although no significant differences were detected in P. mirabilis kidney colonisation of treated and non-treated animals. These results are encouraging and prompt further research related to probiotic strains and the basis of their effects for their use in human and animal health.

  9. Penicillium araracuarense sp. nov., Penicillium elleniae sp. nov., Penicillium penarojense sp. nov., Penicillium vanderhammenii sp. nov. and Penicillium wotroi sp. nov., isolated from leaf litter.

    Science.gov (United States)

    Houbraken, Jos; López-Quintero, Carlos A; Frisvad, Jens C; Boekhout, Teun; Theelen, Bart; Franco-Molano, Ana Esperanza; Samson, Robert A

    2011-06-01

    Several species of the genus Penicillium were isolated during a survey of the mycobiota of leaf litter and soil in Colombian Amazon forest. Five species, Penicillium penarojense sp. nov. (type strain CBS 113178(T) = IBT 23262(T)), Penicillium wotroi sp. nov. (type strain CBS 118171(T) = IBT 23253(T)), Penicillium araracuarense sp. nov. (type strain CBS 113149(T) = IBT 23247(T)), Penicillium elleniae sp. nov. (type strain CBS 118135(T) = IBT 23229(T)) and Penicillium vanderhammenii sp. nov. (type strain CBS 126216(T) = IBT 23203(T)) are described here as novel species. Their taxonomic novelty was determined using a polyphasic approach, combining phenotypic, molecular (ITS and partial β-tubulin sequences) and extrolite data. Phylogenetic analyses showed that each novel species formed a unique clade for both loci analysed and that they were most closely related to Penicillium simplicissimum, Penicillium janthinellum, Penicillium daleae and Penicillium brasilianum. An overview of the phylogeny of this taxonomically difficult group is presented, and 33 species are accepted. Each of the five novel species had a unique extrolite profile of known and uncharacterized metabolites and various compounds, such as penicillic acid, andrastin A, pulvilloric acid, paxillin, paspaline and janthitrem, were commonly produced by these phylogenetically related species. The novel species had a high growth rate on agar media, but could be distinguished from each other by several macro- and microscopical characteristics.

  10. Best-practice life expectancy: An extreme value approach

    Directory of Open Access Journals (Sweden)

    Anthony Medford

    2017-03-01

    Full Text Available Background: Whereas the rise in human life expectancy has been extensively studied, the evolution of maximum life expectancies, i.e., the rise in best-practice life expectancy in a group of populations, has not been examined to the same extent. The linear rise in best-practice life expectancy has been reported previously by various authors. Though remarkable, this is simply an empirical observation. Objective: We examine best-practice life expectancy more formally by using extreme value theory. Methods: Extreme value distributions are fit to the time series (1900 to 2012 of maximum life expectancies at birth and age 65, for both sexes, using data from the Human Mortality Database and the United Nations. Conclusions: Generalized extreme value distributions offer a theoretically justified way to model best-practice life expectancies. Using this framework one can straightforwardly obtain probability estimates of best-practice life expectancy levels or make projections about future maximum life expectancy. Comments: Our findings may be useful for policymakers and insurance/pension analysts who would like to obtain estimates and probabilities of future maximum life expectancies.

  11. Educational Expectations and Media Cultures

    Directory of Open Access Journals (Sweden)

    Petra Missomelius

    2014-11-01

    Full Text Available This article investigates themedia-supported educational resources that arecurrently under discussion, such as OERs and MOOCs. Considering the discursive connection between these formats, which is couched in terms of educational freedom and openness, the article’sthesis is that these are expectations which are placed on the media technologies themselves, andthen transferred to learning scenarios. To this end, the article will pursue such questions as: What are the learners, learning materials and learning scenarios allegedly free from or free for? What obstructive configurations should be omitted? To what extent are these characteristics which are of a nature to guaranteelearning processes in the context of lifelong learning or can these characteristics better be attributed to the media technologies themselves and the ways in which they are used? What advantages or new accentuations are promised by proponents of theeducation supplied by media technology? Which discourses provide sustenance for such implied “post-typographic educational ideals” (Giesecke 2001 and Lemke 1998? The importance to learners, teachers and decision-makers at educational institutions of being well informed as far as media is concerned is becoming increasingly apparent.

  12. A new double digestion ligation mediated suppression PCR method for simultaneous bacteria DNA-typing and confirmation of species: an Acinetobacter sp. model.

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    Karolina Stojowska

    Full Text Available We have designed a new ddLMS PCR (double digestion Ligation Mediated Suppression PCR method based on restriction site polymorphism upstream from the specific target sequence for the simultaneous identification and differentiation of bacterial strains. The ddLMS PCR combines a simple PCR used for species or genus identification and the LM PCR strategy for strain differentiation. The bacterial identification is confirmed in the form of the PCR product(s, while the length of the PCR product makes it possible to differentiate between bacterial strains. If there is a single copy of the target sequence within genomic DNA, one specific PCR product is created (simplex ddLMS PCR, whereas for multiple copies of the gene the fingerprinting patterns can be obtained (multiplex ddLMS PCR. The described ddLMS PCR method is designed for rapid and specific strain differentiation in medical and microbiological studies. In comparison to other LM PCR it has substantial advantages: enables specific species' DNA-typing without the need for pure bacterial culture selection, is not sensitive to contamination with other cells or genomic DNA, and gives univocal "band-based" results, which are easy to interpret. The utility of ddLMS PCR was shown for Acinetobacter calcoaceticus-baumannii (Acb complex, the genetically closely related and phenotypically similar species and also important nosocomial pathogens, for which currently, there are no recommended methods for screening, typing and identification. In this article two models are proposed: 3' recA-ddLMS PCR-MaeII/RsaI for Acb complex interspecific typing and 5' rrn-ddLMS PCR-HindIII/ApaI for Acinetobacter baumannii intraspecific typing. ddLMS PCR allows not only for DNA-typing but also for confirmation of species in one reaction. Also, practical guidelines for designing a diagnostic test based on ddLMS PCR for genotyping different species of bacteria are provided.

  13. A new double digestion ligation mediated suppression PCR method for simultaneous bacteria DNA-typing and confirmation of species: an Acinetobacter sp. model.

    Science.gov (United States)

    Stojowska, Karolina; Krawczyk, Beata

    2014-01-01

    We have designed a new ddLMS PCR (double digestion Ligation Mediated Suppression PCR) method based on restriction site polymorphism upstream from the specific target sequence for the simultaneous identification and differentiation of bacterial strains. The ddLMS PCR combines a simple PCR used for species or genus identification and the LM PCR strategy for strain differentiation. The bacterial identification is confirmed in the form of the PCR product(s), while the length of the PCR product makes it possible to differentiate between bacterial strains. If there is a single copy of the target sequence within genomic DNA, one specific PCR product is created (simplex ddLMS PCR), whereas for multiple copies of the gene the fingerprinting patterns can be obtained (multiplex ddLMS PCR). The described ddLMS PCR method is designed for rapid and specific strain differentiation in medical and microbiological studies. In comparison to other LM PCR it has substantial advantages: enables specific species' DNA-typing without the need for pure bacterial culture selection, is not sensitive to contamination with other cells or genomic DNA, and gives univocal "band-based" results, which are easy to interpret. The utility of ddLMS PCR was shown for Acinetobacter calcoaceticus-baumannii (Acb) complex, the genetically closely related and phenotypically similar species and also important nosocomial pathogens, for which currently, there are no recommended methods for screening, typing and identification. In this article two models are proposed: 3' recA-ddLMS PCR-MaeII/RsaI for Acb complex interspecific typing and 5' rrn-ddLMS PCR-HindIII/ApaI for Acinetobacter baumannii intraspecific typing. ddLMS PCR allows not only for DNA-typing but also for confirmation of species in one reaction. Also, practical guidelines for designing a diagnostic test based on ddLMS PCR for genotyping different species of bacteria are provided.

  14. Petroleum systems and hydrocarbon accumulation models in the Santos Basin, SP, Brazil; Sistemas petroliferos e modelos de acumulacao de hidrocarbonetos na Bacia de Santos

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Hung Kiang; Assine, Mario Luis; Correa, Fernando Santos; Tinen, Julio Setsuo [Universidade Estadual Paulista (UNESP), Rio Claro, SP (Brazil). Lab. de Estudos de Bacias]. E-mails: chang@rc.unesp.br; assine@rc.unesp.br; fscorrea@rc.unesp.br; jstinen@rc.unesp.br; Vidal, Alexandre Campane; Koike, Luzia [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Centro de Estudos de Petroleo]. E-mails: vidal@ige.unicamp.br; luzia@iqm.unicamp.br

    2008-07-01

    The Santos Basin was formed by rifting process during Mesozoic Afro-American separation. Sediment accumulation initiated with fluvial-lacustrine deposits, passing to evaporitic stage until reaching marginal basin stages. The analysis of hydrocarbon potential of Santos Basin identified two petroleum systems: Guaratiba-Guaruja and Itajai-Acu-Ilhabela. The Guaratiba Formation is less known in the Santos Basin because of small number of wells that have penetrated the rift section. By comparison with Campos Basin, hydrocarbons are of saline lacustrine origin deposited in Aptian age. Analogous to Campos Basin the major source rock is of saline-lacustrine origin, which has been confirmed from geochemical analyses of oil samples recovered from the various fields. These analyses also identified marine source rock contribution, indicating the Itajai-Acu source rock went through oil-window, particularly in structural lows generated by halokynesis. Models of hydrocarbon accumulation consider Guaratiba Formacao as the major source rock for shallow carbonate reservoirs of Guaruja Formacao and for late Albian to Miocene turbidites, as well as siliciclastic and carbonate reservoirs of the rift phase. Migration occurs along salt window and through carrier-beds. The seal rock is composed of shales and limestones intercalated with reservoir facies of the post-rift section and by thick evaporites overlying rift section, especially in the deeper water. In the shallow portion, shale inter-tongued with reservoir rocks is the main seal rock. The hydrocarbon generation and expulsion in the central-north portion of the basin is caused by overburden of a thick Senonian section. Traps can be structural (rollovers and turtle), stratigraphic (pinch-outs) and mixed origins (pinch-outs of turbidites against salt domes). (author)

  15. Neues vom Heringsparasiten Ichthyophonus sp.

    OpenAIRE

    Lang, Thomas

    1994-01-01

    Seit dem Massensterben von Heringen entlang der schwedischen Südküste im Sommer 1991, aufgrund einer Infektion mit dem parasitischen Pilz Ichthyophonus sp., wird der Gesundheitszustand der Heringsbestände in den europäischen Seegebieten intensiv überwacht. Diese Untersuchungen, an denen sich auch die Bundesforschungsanstalt für Fischerei beteiligt, werden koordiniert von der "Arbeitsgruppe über Pathologie und Krankheiten mariner Organismen" des Internationalen Rates für Meeresforschung (IC...

  16. Assessment of expected breeding values for fertility traits of Murrah buffaloes under subtropical climate

    Directory of Open Access Journals (Sweden)

    Soumya Dash

    2015-03-01

    Full Text Available Aim: The aim of the present study was to assess the influence of temperature and humidity prevalent under subtropical climate on the breeding values for fertility traits viz. service period (SP, pregnancy rate (PR and conception rate (CR of Murrah buffaloes in National Dairy Research Institute (NDRI herd. Materials and Methods: Fertility data on 1379 records of 581 Murrah buffaloes spread over four lactations and climatic parameters viz. dry bulb temperature and relative humidity (RH spanned over 20 years (1993-2012 were collected from NDRI and Central Soil and Salinity Research Institute, Karnal, India. Monthly average temperature humidity index (THI values were estimated. Threshold THI value affecting fertility traits was identified by fixed least-squares model analysis. Three zones of non-heat stress, heat stress and critical heat stress zones were developed in a year. The genetic parameters heritablility (h2 and repeatability (r of each fertility trait were estimated. Genetic evaluation of Murrah buffaloes was performed in each zone with respect to their expected breeding values (EBV for fertility traits. Results: Effect of THI was found significant (p<0.001 on all fertility traits with threshold THI value identified as 75. Based on THI values, a year was classified into three zones: Non heat stress zone(THI 56.71-73.21, HSZ (THI 75.39-81.60 and critical HSZ (THI 80.27-81.60. The EBVfor SP, PR, CR were estimated as 138.57 days, 0.362 and 69.02% in non-HSZ while in HSZ EBV were found as 139.62 days, 0.358 and 68.81%, respectively. EBV for SP was increased to 140.92 days and for PR and CR, it was declined to 0.357 and 68.71% in critical HSZ. Conclusion: The negative effect of THI was observed on EBV of fertility traits under the non-HSZ and critical HSZ Thus, the influence of THI should be adjusted before estimating the breeding values for fertility traits in Murrah buffaloes.

  17. Assessment of In Vivo Antidiabetic Properties of Umbelliferone and Lupeol Constituents of Banana (Musa sp. var. Nanjangud Rasa Bale) Flower in Hyperglycaemic Rodent Model.

    Science.gov (United States)

    Ramu, Ramith; S Shirahatti, Prithvi; S, Nanjunda Swamy; Zameer, Farhan; Lakkappa Dhananjaya, Bhadrapura; M N, Nagendra Prasad

    2016-01-01

    Banana is an extensively cultivated plant worldwide, mainly for its fruit, while its ancillary product, the banana flower is consumed as a vegetable and is highly recommended for diabetics in the traditional Indian medicine system. This study is based on an investigation of the in vivo antihyperglycaemic activity of Umbelliferone (C1) and Lupeol (C2) isolated from the ethanol extract of banana flower (EF) in alloxan induced diabetic rat model. Diabetic rats which were administered with C1, C2 and EF (100 and 200 mg/kg b. wt.) for 4 weeks showed deterioration in fasting hyperglycaemia and reversal of abnormalities in serum/urine protein, urea and creatinine, when compared to the diabetic control group of rats. The diabetic group of rats fed with EF, C1 and C2 (100 mg/kg b. wt.) once daily, for a period of 28 days resulted in a significant reduction of diabetic symptoms viz., polyphagia, polydipsia, polyuria and urine sugar together with an improved body weight. HbA1c extent was reduced whereas levels of insulin and Hb were increased. Both the extract and compounds wielded positive impacts in diabetic rats by reversal of altered activities of hepatic marker enzymes viz., aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP); glycolytic enzyme (hexokinase); shunt enzyme (glucose-6-phosphate dehydrogenase); gluconeogenic enzymes (glucose-6-phosphatase, fructose-1,6-bisphosphatase, lactate dehydrogenase) and pyruvate kinase. The characteristic diabetic complications such as hypercholesterolemia and hypertriacylglycerolemia also significantly reverted to normal in the serum/liver of diabetic rats. Besides these, the treatment increased the activities of enzymatic and non-enzymatic antioxidants in the serum and liver. The histological observations revealed a marked regeneration of the β-cells in the drug treated diabetic rats. In conclusion, the present study illustrates that EF, C1 and C2 enhances the glycolytic activities, besides

  18. Assessment of In Vivo Antidiabetic Properties of Umbelliferone and Lupeol Constituents of Banana (Musa sp. var. Nanjangud Rasa Bale Flower in Hyperglycaemic Rodent Model.

    Directory of Open Access Journals (Sweden)

    Ramith Ramu

    Full Text Available Banana is an extensively cultivated plant worldwide, mainly for its fruit, while its ancillary product, the banana flower is consumed as a vegetable and is highly recommended for diabetics in the traditional Indian medicine system. This study is based on an investigation of the in vivo antihyperglycaemic activity of Umbelliferone (C1 and Lupeol (C2 isolated from the ethanol extract of banana flower (EF in alloxan induced diabetic rat model. Diabetic rats which were administered with C1, C2 and EF (100 and 200 mg/kg b. wt. for 4 weeks showed deterioration in fasting hyperglycaemia and reversal of abnormalities in serum/urine protein, urea and creatinine, when compared to the diabetic control group of rats. The diabetic group of rats fed with EF, C1 and C2 (100 mg/kg b. wt. once daily, for a period of 28 days resulted in a significant reduction of diabetic symptoms viz., polyphagia, polydipsia, polyuria and urine sugar together with an improved body weight. HbA1c extent was reduced whereas levels of insulin and Hb were increased. Both the extract and compounds wielded positive impacts in diabetic rats by reversal of altered activities of hepatic marker enzymes viz., aspartate transaminase (AST, alanine transaminase (ALT, alkaline phosphatase (ALP; glycolytic enzyme (hexokinase; shunt enzyme (glucose-6-phosphate dehydrogenase; gluconeogenic enzymes (glucose-6-phosphatase, fructose-1,6-bisphosphatase, lactate dehydrogenase and pyruvate kinase. The characteristic diabetic complications such as hypercholesterolemia and hypertriacylglycerolemia also significantly reverted to normal in the serum/liver of diabetic rats. Besides these, the treatment increased the activities of enzymatic and non-enzymatic antioxidants in the serum and liver. The histological observations revealed a marked regeneration of the β-cells in the drug treated diabetic rats. In conclusion, the present study illustrates that EF, C1 and C2 enhances the glycolytic activities

  19. Forecasting in the presence of expectations

    Science.gov (United States)

    Allen, R.; Zivin, J. G.; Shrader, J.

    2016-05-01

    Physical processes routinely influence economic outcomes, and actions by economic agents can, in turn, influence physical processes. This feedback creates challenges for forecasting and inference, creating the potential for complementarity between models from different academic disciplines. Using the example of prediction of water availability during a drought, we illustrate the potential biases in forecasts that only take part of a coupled system into account. In particular, we show that forecasts can alter the feedbacks between supply and demand, leading to inaccurate prediction about future states of the system. Although the example is specific to drought, the problem of feedback between expectations and forecast quality is not isolated to the particular model-it is relevant to areas as diverse as population assessments for conservation, balancing the electrical grid, and setting macroeconomic policy.

  20. Forecasting differences in life expectancy by education.

    Science.gov (United States)

    van Baal, Pieter; Peters, Frederik; Mackenbach, Johan; Nusselder, Wilma

    2016-07-01

    Forecasts of life expectancy (LE) have fuelled debates about the sustainability and dependability of pension and healthcare systems. Of relevance to these debates are inequalities in LE by education. In this paper, we present a method of forecasting LE for different educational groups within a population. As a basic framework we use the Li-Lee model that was developed to forecast mortality coherently for different groups. We adapted this model to distinguish between overall, sex-specific, and education-specific trends in mortality, and extrapolated these time trends in a flexible manner. We illustrate our method for the population aged 65 and over in the Netherlands, using several data sources and spanning different periods. The results suggest that LE is likely to increase for all educational groups, but that differences in LE between educational groups will widen. Sensitivity analyses illustrate the advantages of our proposed method.