WorldWideScience

Sample records for source material editions

  1. Standard and reference materials for marine science. Third edition. Technical memo

    International Nuclear Information System (INIS)

    Cantillo, A.Y.

    1992-08-01

    The third edition of the catalog of reference materials suited for use in marine science, originally compiled in 1986 for NOAA, IOC, and UNEP. The catalog lists close to 2,000 reference materials from sixteen producers and contains information about their proper use, sources, availability, and analyte concentrations. Indices are included for elements, isotopes, and organic compounds, as are cross references to CAS registry numbers, alternate names, and chemical structures of selected organic compounds. The catalog is being published independently by both NOAA and IOC/UNEP and is available from NOAA/NOS/ORCA in electronic form

  2. Collecting and Interpreting Qualitative Materials. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna, Ed.

    2007-01-01

    This book is the third volume of the paperback versions of "The SAGE Handbook of Qualitative Research, Third Edition." This portion of the handbook considers the tasks of collecting, analyzing, and interpreting empirical materials, and comprises the Handbook's Parts IV ("Methods of Collecting and Analyzing Empirical Materials") and V ("The Art and…

  3. Environmental Radioactivity from Natural, Industrial and Military Sources. 4th Edition

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Steve

    1998-09-01

    Merril Eisenbud's series of books on environmental radioactivity have long had a place on the bookshelves of those involved with the environmental aspects of radiation protection. They provide authoritative coverage of the subject including sources, transport mechanisms and effects. The first edition, published in 1963, was naturally mostly concerned with the effects of nuclear weapons testing in the atmosphere. The second edition, published in 1977, reflected the then expansive phase of nuclear power development worldwide and included an extensive treatment of the nuclear fuel cycle and its contributions to environmental radioactivity. In 1987 the third edition included coverage of the Three Mile Island accident and the Chernobyl accident against the background of cessation of new orders for nuclear plant in the United States. The fourth edition is a major revision with a lot of new material, and the welcome adoption of SI units throughout. The principal additions to the new edition are chapters on environmental surveillance, radiological assessment and dose reconstruction, and the remediation of contaminated sites; nothing has been lost from the extensive coverage of other topics in the third edition, whilst the text and bibliography have been revised and brought up to date. Earlier editions of the book have provided good summaries of accidents which have resulted in environmental contamination, and the updating here results in more extensive and up-to-date coverage of the Three Mile Island and Chernobyl accidents, including the more recent evidence of health effects from the latter, together with new sections on the Palomares nuclear weapons accident in Spain, the Mayak/Chelyabinsk complex in Russia, and the accidents involving lost gamma radiation sources in Juarez, Mexico and Goiania, Brazil. Both here and in the extensive coverage of contamination at the USDoE production sites the new edition reflects and benefits from the increased public availability

  4. Managing the Incompetent Teacher. Second Edition.

    Science.gov (United States)

    Bridges, Edwin M.

    Featuring the same practical guidelines for ridding schools of incompetent teachers as the 1984 edition, this new edition incorporates substantially revised material on three topics: criteria and information sources for evaluating teaching effectiveness, remediation procedures, and grounds for dismissal. The book presents an eight-step systematic,…

  5. Planning and Producing Audiovisual Materials. Third Edition.

    Science.gov (United States)

    Kemp, Jerrold E.

    A revised edition of this handbook provides illustrated, step-by-step explanations of how to plan and produce audiovisual materials. Included are sections on the fundamental skills--photography, graphics and recording sound--followed by individual sections on photographic print series, slide series, filmstrips, tape recordings, overhead…

  6. An electronic edition of eighteenth-century drama: the materiality of editing in performance

    Directory of Open Access Journals (Sweden)

    Pinto, Isabel

    2016-07-01

    Full Text Available In the domain of electronic edition, drama’s specificity has been considered in terms of metadata improvements and possibilities. At the same time, an increasing closeness between art history research and performance art has demonstrated its methodological value to assess the complex nature of the archive. My post-doctoral research follows the lead and goes as far as proposing that performance art can be an adequate methodology when preparing the electronic edition of eighteenth-century drama. Furthermore, “performing the archive” can help to fill the gap between the eventful nature of drama manuscripts and the audience of today, suggesting new ways of approaching the specific materiality of the plays.

  7. Advisory Material for the IAEA Regulations for the Safe Transport of Radioactive Material. Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    2010-01-01

    This Safety Guide provides recommendations on achieving and demonstrating compliance with IAEA Safety Standards Series No. TS-R-1, Regulations for the Safe Transport of Radioactive Material, 2005 Edition, establishing safety requirements to be applied to the national and international transport of radioactive material. Transport is deemed to comprise all operations and conditions associated with and involved in the movement of radioactive material; these include the design, fabrication and maintenance of packaging, and the preparation, consigning, handling, carriage, storage in transit and receipt at the final destination of packages. This publication supersedes IAEA Safety Series No. TS-G-1.1, 2002 Edition

  8. Explanatory material for the IAEA regulations for the safe transport of radioactive material (1985 edition). 2. ed. (as amended 1990)

    International Nuclear Information System (INIS)

    1990-01-01

    This publication is an updated version of the Second Edition of the Explanatory Material for the IAEA Regulations for the Safe Transport of Radioactive Material (1985 Edition) and replaces all previous versions of Safety Series No. 7. This publication includes the changes to Safety Series No. 7 contained in the Regulations for the Safe Transport of Radioactive Material, 1985 Edition, Supplement 1988, as well as modifications adopted by the Review Panel that was convened in Vienna, 10-14 July 1989. For the convenience of the user, the old Safety Series style adopted in the original publication has been retained, although the old style has now been superseded by a new one, affecting the structure, the format and the cover of the Safety Series. It should be noted, however, that future editions will be published in the new style.

  9. Editing Audio with Audacity

    Directory of Open Access Journals (Sweden)

    Brandon Walsh

    2016-08-01

    Full Text Available For those interested in audio, basic sound editing skills go a long way. Being able to handle and manipulate the materials can help you take control of your object of study: you can zoom in and extract particular moments to analyze, process the audio, and upload the materials to a server to compliment a blog post on the topic. On a more practical level, these skills could also allow you to record and package recordings of yourself or others for distribution. That guest lecture taking place in your department? Record it and edit it yourself! Doing so is a lightweight way to distribute resources among various institutions, and it also helps make the materials more accessible for readers and listeners with a wide variety of learning needs. In this lesson you will learn how to use Audacity to load, record, edit, mix, and export audio files. Sound editing platforms are often expensive and offer extensive capabilities that can be overwhelming to the first-time user, but Audacity is a free and open source alternative that offers powerful capabilities for sound editing with a low barrier for entry. For this lesson we will work with two audio files: a recording of Bach’s Goldberg Variations available from MusOpen and another recording of your own voice that will be made in the course of the lesson. This tutorial uses Audacity 2.1.2, released January 2016.

  10. Regulations for the safe transport of radioactive material, 2005 edition. Safety requirements

    International Nuclear Information System (INIS)

    2005-01-01

    This publication includes amendments to the 1996 Edition (As Amended 2003) arising from the second cycle of the biennial review and revision process, as agreed by the Transport Safety Standards Committee (TRANSSC) at its ninth meeting in March 2004, as endorsed by the Commission on Safety Standards at its meeting in June 2004 and as approved by the IAEA Board of Governors in November 2004. Although this publication is identified as a new edition, there are no changes that affect the administrative and approval requirements in Section VIII. The fields covered are General Provisions (radiation protection; emergency response; quality assurance; compliance assurance; non-compliance; special arrangement and training); Activity Limits and Materials Restrictions, Requirement and Controls for Transport , Requirements for Radioactive Materials and for Packagings and Packages, Test Procedures, Approval and Administrative Requirements

  11. Fundamentals of Welding. Teacher Edition [and] Student Edition [and] Student Workbook. Second Edition.

    Science.gov (United States)

    Fortney, Clarence; Gregory, Mike; New, Larry

    Teacher and student editions and a student workbook for fundamentals of welding comprise the first of six in a series of competency-based instructional materials for welding programs. Introductory pages in the teacher edition are training and competency profile, instructional/task analysis, basic skills icons and classifications, basic skills…

  12. Introduction to Special Edition (of the Journal of Nuclear Materials Management) on Reducing the Threat from Radioactive Materials

    International Nuclear Information System (INIS)

    Mladineo, Stephen V.

    2007-01-01

    Introductory article for special edition of the JOURNAL OF NUCLEAR MATERIALS MANAGEMENT outlining the Institute of Nuclear Materials Management Nonproliferation and Arms Control Technical Division. In particular the International Nuclear and Radiological Security Standing Committee and its initial focus covering four topical areas--Radiological Threat Reduction, Nuclear Smuggling and Illicit Trafficking, Countering Nuclear Terrorism, and Radiological Terrorism Consequence Management

  13. INES: The International Nuclear and Radiological Event Scale User's Manual. 2008 Edition (Spanish Edition)

    International Nuclear Information System (INIS)

    2010-11-01

    INES, the International Nuclear and Radiological Event Scale, was developed in 1990 by experts convened by the IAEA and the OECD Nuclear Energy Agency with the aim of communicating the safety significance of events. This edition of the INES User?s Manual is designed to facilitate the task of those who are required to rate the safety significance of events using the scale. It includes additional guidance and clarifications, and provides examples and comments on the continued use of INES. With this new edition, it is anticipated that INES will be widely used by Member States and become the worldwide scale for putting into proper perspective the safety significance of any event associated with the transport, storage and use of radioactive material and radiation sources, whether or not the event occurs at a facility.

  14. INES: The International Nuclear and Radiological Event Scale User's Manual. 2008 Edition (Chinese Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    INES, the International Nuclear and Radiological Event Scale, was developed in 1990 by experts convened by the IAEA and the OECD Nuclear Energy Agency with the aim of communicating the safety significance of events. This edition of the INES User's Manual is designed to facilitate the task of those who are required to rate the safety significance of events using the scale. It includes additional guidance and clarifications, and provides examples and comments on the continued use of INES. With this new edition, it is anticipated that INES will be widely used by Member States and become the worldwide scale for putting into proper perspective the safety significance of any event associated with the transport, storage and use of radioactive material and radiation sources, whether or not the event occurs at a facility.

  15. Primary Sources: America's Teachers on Teaching in an Era of Change. Third Edition

    Science.gov (United States)

    Scholastic Inc. and the Bill & Melinda Gates Foundation, 2013

    2013-01-01

    This third edition of "Primary Sources" represents a joint project of Scholastic and the Bill & Melinda Gates Foundation. It reports the views of more than 20,000 public school teachers on important issues related to their profession. Fielded in July 2013, the survey asks teachers about their motivation, new learning standards,…

  16. ROCAM: The 5-th International Edition of Romanian Conference on Advanced Materials. Abstracts

    International Nuclear Information System (INIS)

    Stanculescu, Florin

    2006-01-01

    The proceedings of the 5-th International Edition of Romanian Conference on Advanced Materials and Crystal Growth with special topics on nano and multifunctional materials held on September 11-14, 2006 in Bucharest- Magurele, Romania, contains contributions presented as plenary lectures, invited papers and regular contributions in eight sections, namely: 1. Growth and characterization of inorganic crystals; 2. Growth and characterization of organic and biological crystals; 3. Nano and microstructured materials and thin films; 4. Polymers/fuel cells and hydrogen storage; 5. Plasma deposition and applications; 6. Advanced processing and characterization / noncrystalline solids; 7. Advanced nuclear materials; 8. Advanced materials: general aspects

  17. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 2001 edition

    International Nuclear Information System (INIS)

    2001-08-01

    The current edition of the transport Regulations was published in 1996 and is more commonly referred to as 'ST-1'. Earlier Editions were known as Safety Series No. 6. The latest English reprint (2000) is now identified as TS-R-1 (ST-1, Revised). The transport Regulations elaborate requirements for the design, fabrication and maintenance of packaging as well as those for preparation, consigning, handling, carriage, storage in transit and receipt of the packages at final destination. Approval issued in the form of certificates is required for the design or shipment of packages. This report supersedes IAEA-TECDOC-1171 D irectory of National Competent Authorities' Approval Certificates for Package Design, Special Form Material and Shipment of Radioactive Material, 2000 Edition . It is distributed worldwide to the IAEA Member States' competent authorities for transport, and other entities who have requested copies. Electronic copies of the main data file are provided to registered users of the PACKTRAM database. The information contained in this report is given in six tables. In each of these, information is presented in alphabetical order based on the certificate number. Tables 1 to 4 present administrative data including issue and expiry dates, package identification, package serial numbers, modes for which the package/shipment is approved and the edition of the IAEA Transport Safety Regulations on which the approval has been based. The technical information on package mass, authorized contents, and detailed and general description of the package are contained in Table 5. Table 6 shows the certificates reported to the Secretariat by each participating Member State

  18. Radiation Protection and Safety of Radiation Sources: International Basic Safety Standards. General Safety Requirements. Pt. 3 (Chinese Edition)

    International Nuclear Information System (INIS)

    2014-01-01

    This publication is the new edition of the International Basic Safety Standards. The edition is co-sponsored by seven other international organizations — European Commission (EC/Euratom), FAO, ILO, OECD/NEA, PAHO, UNEP and WHO. It replaces the interim edition that was published in November 2011 and the previous edition of the International Basic Safety Standards which was published in 1996. It has been extensively revised and updated to take account of the latest finding of the United Nations Scientific Committee on the Effects of Atomic Radiation, and the latest recommendations of the International Commission on Radiological Protection. The publication details the requirements for the protection of people and the environment from harmful effects of ionizing radiation and for the safety of radiation sources. All circumstances of radiation exposure are considered

  19. Radiation protection and safety of radiation sources: International basic safety standards. General safety requirements. Pt. 3 (French Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication is the new edition of the International Basic Safety Standards. The edition is co-sponsored by seven other international organizations — European Commission (EC/Euratom), FAO, ILO, OECD/NEA, PAHO, UNEP and WHO. It replaces the interim edition that was published in November 2011 and the previous edition of the International Basic Safety Standards which was published in 1996. It has been extensively revised and updated to take account of the latest finding of the United Nations Scientific Committee on the Effects of Atomic Radiation, and the latest recommendations of the International Commission on Radiological Protection. The publication details the requirements for the protection of people and the environment from harmful effects of ionizing radiation and for the safety of radiation sources. All circumstances of radiation exposure are considered

  20. Radiation Protection and Safety of Radiation Sources: International Basic Safety Standards. General Safety Requirements. Pt. 3 (Arabic Edition)

    International Nuclear Information System (INIS)

    2015-01-01

    This publication is the new edition of the International Basic Safety Standards. The edition is co-sponsored by seven other international organizations — European Commission (EC/Euratom), FAO, ILO, OECD/NEA, PAHO, UNEP and WHO. It replaces the interim edition that was published in November 2011 and the previous edition of the International Basic Safety Standards which was published in 1996. It has been extensively revised and updated to take account of the latest finding of the United Nations Scientific Committee on the Effects of Atomic Radiation, and the latest recommendations of the International Commission on Radiological Protection. The publication details the requirements for the protection of people and the environment from harmful effects of ionizing radiation and for the safety of radiation sources. All circumstances of radiation exposure are considered

  1. An electronic edition of eighteenth-century drama: the materiality of editing in performance

    OpenAIRE

    Pinto, Isabel

    2016-01-01

    In the domain of electronic edition, drama’s specificity has been considered in terms of metadata improvements and possibilities. At the same time, an increasing closeness between art history research and performance art has demonstrated its methodological value to assess the complex nature of the archive. My post-doctoral research follows the lead and goes as far as proposing that performance art can be an adequate methodology when preparing the electronic edition of eighteenth-century drama...

  2. Handbook on Lead-bismuth Eutectic Alloy and Lead Properties, Materials Compatibility, Thermal-hydraulics and Technologies - 2015 Edition

    International Nuclear Information System (INIS)

    Fazio, Concetta; Sobolev, V.P.; Aerts, A.; Gavrilov, S.; Lambrinou, K.; Schuurmans, P.; Gessi, A.; Agostini, P.; Ciampichetti, A.; Martinelli, L.; Gosse, S.; Balbaud-Celerier, F.; Courouau, J.L.; Terlain, A.; Li, N.; Glasbrenner, H.; Neuhausen, J.; Heinitz, S.; Zanini, L.; Dai, Y.; Jolkkonen, M.; Kurata, Y.; Obara, T.; Thiolliere, N.; Martin-Munoz, F.J.; Heinzel, A.; Weisenburger, A.; Mueller, G.; Schumacher, G.; Jianu, A.; Pacio, J.; Marocco, L.; Stieglitz, R.; Wetzel, T.; Daubner, M.; Litfin, K.; Vogt, J.B.; Proriol-Serre, I.; Gorse, D.; Eckert, S.; Stefani, F.; Buchenau, D.; Wondrak, T.; Hwang, I.S.

    2015-01-01

    Heavy liquid metals such as lead or lead-bismuth have been proposed and investigated as coolants for fast reactors since the 1950's. More recently, there has been renewed interest worldwide in the use of these materials to support the development of systems for the transmutation of radioactive waste. Heavy liquid metals are also under evaluation as a reactor core coolant and accelerator-driven system neutron spallation source. Several national and international R and D programmes are ongoing for the development of liquid lead-alloy technology and the design of liquid lead-alloy-cooled reactor systems. In 2007, a first edition of the handbook was published to provide deeper insight into the properties and experimental results in relation to lead and lead-bismuth eutectic technology and to establish a common database. This handbook remains a reference in the field and is a valuable tool for designers and researchers with an interest in heavy liquid metals. The 2015 edition includes updated data resulting from various national and international R and D programmes and contains new experimental data to help understand some important phenomena such as liquid metal embrittlement and turbulent heat transfer in a fuel bundle. The handbook provides an overview of liquid lead and lead-bismuth eutectic properties, materials compatibility and testing issues, key aspects of thermal-hydraulics and existing facilities, as well as perspectives for future R and D. (authors)

  3. Material-specific retroactive interference effects of the Wechsler Adult Intelligence Scale-Fourth Edition on the Wechsler Memory Scale-Fourth Edition in a nonclinical sample.

    Science.gov (United States)

    Ingram, Nicolette S; Diakoumakos, Jessica V; Sinclair, Erin R; Crowe, Simon F

    2016-01-01

    This study investigated proactive and retroactive interference effects between the Wechsler Memory Scale-Fourth Edition (WMS-IV) using the flexible approach, and the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). One hundred and eighty nonclinical participants were assigned to a four (visual interference, verbal interference, visual and verbal interference, vs. no interference) by two (retroactive vs. proactive) between-subjects design. The administration order of the tests was counterbalanced (i.e., administration of the WAIS-IV prior to the WMS-IV, and the WAIS-IV administered during the delay interval of the WMS-IV). The WAIS-IV produced significant retroactive interference effects on the WMS-IV; however, no proactive interference effect was observed. The retroactive interference effect was dependent on material specificity. The results indicate that material presented within the delay of the WMS-IV can have a significant effect on subsequent delayed recall. Clinicians should carefully consider the effects associated with carry-over effects of these tests when using them in combination.

  4. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 1991 edition

    International Nuclear Information System (INIS)

    1991-08-01

    The format of this report is a result of recommendations made by the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM) at its 6th meeting in November 1987. The database was at that time maintained on the main frame and it was felt that adapting it for use on a personal computer would allow more flexibility in data processing and reporting. This document supersedes TECDOC-552 ''Directory of National Competent Authorities' Approval Certificates for Package Design and Shipment of Radioactive Material 1990 Edition''. Since publication of TECDOC-552, some modifications affecting the structure of the database and reporting formats were undertaken. These are fully described in ''Working Material: The PACKTRAM Database National Competent Authority Package Approval Certificates, User Guide Rev. 1'', which was released in early 1991. The present report is contained in five tables. In each of these, information is presented in alphabetical order based on the certificate number. This is composed of the issuing Member State's VRI code, followed by a slash, then a three- or four-digit number, another slash and finally a code identifying the type of package involved. ''-85'' is appended to those certificates that were approved on the basis of the 1985 Edition of Safety Series No. 6. Tables 1 to 4 present administrative data including issue and expire, dates, package identification, package serial numbers, modes for which the package/shipment is approved and the edition of Safety Series No. 6 on which the approval has been based. The technical information on package mass, authorized contents, and detailed and general description of the package are contained in Table. 5

  5. Exclusions, exemptions and low specific activity material in the 1996 edition of the IAEA regulations for the safe transport of radioactive material

    International Nuclear Information System (INIS)

    Baekelandt, L.

    1997-01-01

    Exclusions and exemptions, total as well as partial, have always been part of the IAEA transport regulations, but these provisions were dispersed over various sections. In the 1996 edition of these regulations, some of these exclusions and exemptions have been kept unchanged, others have been changed and also, new ones have been added. This paper gives an overview of the exclusions and exemptions in the 1996 edition, the most important change with respect to the previous edition being the departure from the single exemption value of 70 Bq/g for all radionuclides to the radionuclide specific exemption values as specified in the IAEA Basic Safety Standards. As a consequence of this change, a new category of Low Specific Activity (LSA) material has been introduced. This paper also discusses the rationale of these changes to the regulations. (author)

  6. Control of Orphan Sources and Other Radioactive Material in the Metal Recycling and Production Industries. Specific Safety Guide (Arabic Edition)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-09-01

    Accidents involving orphan sources and other radioactive material in the metal recycling and production industries have resulted in serious radiological accidents as well as in harmful environmental, social and economic impacts. This Safety Guide provides recommendations, the implementation of which should prevent such accidents and provide confidence that scrap metal and recycled products are safe. Contents: 1. Introduction; 2. Protection of people and the environment; 3. Responsibilities; 4. Monitoring for radioactive material; 5. Response to the discovery of radioactive material; 6. Remediation of contaminated areas; 7. Management of recovered radioactive material; Annex I: Review of events involving radioactive material in the metal recycling and production industries; Annex II: Categorization of radioactive sources; Annex III: Some examples of national and international initiatives.

  7. Control of Orphan Sources and Other Radioactive Material in the Metal Recycling and Production Industries. Specific Safety Guide (Arabic Edition)

    International Nuclear Information System (INIS)

    2014-01-01

    Accidents involving orphan sources and other radioactive material in the metal recycling and production industries have resulted in serious radiological accidents as well as in harmful environmental, social and economic impacts. This Safety Guide provides recommendations, the implementation of which should prevent such accidents and provide confidence that scrap metal and recycled products are safe. Contents: 1. Introduction; 2. Protection of people and the environment; 3. Responsibilities; 4. Monitoring for radioactive material; 5. Response to the discovery of radioactive material; 6. Remediation of contaminated areas; 7. Management of recovered radioactive material; Annex I: Review of events involving radioactive material in the metal recycling and production industries; Annex II: Categorization of radioactive sources; Annex III: Some examples of national and international initiatives

  8. Control of Orphan Sources and Other Radioactive Material in the Metal Recycling and Production Industries. Specific Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    2013-01-01

    Accidents involving orphan sources and other radioactive material in the metal recycling and production industries have resulted in serious radiological accidents as well as in harmful environmental, social and economic impacts. This Safety Guide provides recommendations, the implementation of which should prevent such accidents and provide confidence that scrap metal and recycled products are safe. Contents: 1. Introduction; 2. Protection of people and the environment; 3. Responsibilities; 4. Monitoring for radioactive material; 5. Response to the discovery of radioactive material; 6. Remediation of contaminated areas; 7. Management of recovered radioactive material; Annex I: Review of events involving radioactive material in the metal recycling and production industries; Annex II: Categorization of radioactive sources; Annex III: Some examples of national and international initiatives

  9. The national plan of radioactive materials and wastes management. 2010-2012 edition

    International Nuclear Information System (INIS)

    2010-01-01

    This short presentation, given by the nuclear safety authority (ASN) at the meeting of January 26, 2010 of the high committee for the nuclear safety transparency and information (HCTISN), describes the different stages of the elaboration of the new edition of the French national plan of radioactive materials and wastes management (PNGMDR). The plan comprises 3 parts: the principles and objectives of the radioactive materials and wastes management, the status of existing procedures and of procedures still under development by the end of 2009, the improvements made. The topics concern: the interim storage, the long-term management and the global consistency of the plan. (J.S.)

  10. Implementation of the 1996 edition of the IAEA regulations for the safe transport of radioactive material

    International Nuclear Information System (INIS)

    Rawl, R.R.; Kervella, O.

    1998-01-01

    The International Atomic Energy Agency (IAEA) completed a 10 year and revision of its 'Regulations for the Safe Transport of Radioactive Material' with approval of the amendments by its Board of Governors in September 1996. The revised edition contains some important changes in the regulations, including: type C package requirements; provisions for low dispersible material; uranium hexafluoride packaging; exemption value specifications; operational requirements, including the creation of a criticality safety index and new proper shipping names/UN numbers. The 1996 edition of the IAEA regulations has been published and corresponding revisions now being considered by the international transport safety organizations and Member States. In particular, the United Nations Committee of Experts on the Transport of Dangerous Goods, International Civil Aviation Organization and International Maritime Organization and preparing revisions to take into account the revised Class 7 requirements. An effective date of 1 January 2001 has been recommended so that international and domestic requirements might come into force simultaneously, thereby avoiding disruptive out-of-phase implementation. (authors)

  11. Peer editing: a strategic source in EFL students’ writing process

    Directory of Open Access Journals (Sweden)

    Nubia Mercedes Díaz Galvis

    2011-06-01

    Full Text Available This article reports on a research project focused on peer editing as a pedagogical tool to promote collaborative assessment in the EFL writing process. With teachers overstretched in the Bogotá public school system, a method needed to be found that would allow students to receive much needed feedback without overtaxing the teachers` resources. Peer editing, a phenomenon that often occurs naturally within the classroom, was therefore systematically implemented as a solution to the stated problem. The main aims of this study, conducted with a group of ninth grade student at a public school in Bogotá, were to determine the role of peer editing in the writing process and to characterize the relationships built when students corrected each others writings. The instruments used for collecting data were field notes, video recordings and students’ artifacts. The results showed that when students were engaged in peer editing sessions they created zones of proximal development in which high achiever students provided linguistic scaffolding and empowered low achievers. It was also found that students used thinking strategies such as noticing and explaining when they identified errors related to the formal aspects of the language.

  12. Revising and editing for translators

    CERN Document Server

    Mossop, Brian

    2014-01-01

    Revising and Editing for Translators provides guidance and learning materials for translation students learning to edit texts written by others, and professional translators wishing to improve their self-revision ability or learning to revise the work of others. Editing is understood as making corrections and improvements to texts, with particular attention to tailoring them to the given readership. Revising is this same task applied to draft translations. The linguistic work of editors and revisers is related to the professional situations in which they work. Mossop offers in-depth coverage of a wide range of topics, including copyediting, style editing, structural editing, checking for consistency, revising procedures and principles, and translation quality assessment. This third edition provides extended coverage of computer aids for revisers, and of the different degrees of revision suited to different texts. The inclusion of suggested activities and exercises, numerous real-world examples, a proposed gra...

  13. Advisory material for the IAEA regulations for the safe transport of radioactive material. Safety guide

    International Nuclear Information System (INIS)

    2008-01-01

    Since the first edition in 1961, the Regulations for the Safe Transport of Radioactive Material of the IAEA (IAEA Regulations) have served as the basis of safety for the transport of radioactive material worldwide. In the discussions leading to the first edition of the IAEA Regulations, it was realized that there was need for a publication to supplement the Regulations which could give information of individual provisions as to their purpose, their scientific background and how to apply them in practice. In response, the Agency published Safety Series No. 7, entitled, in its first edition in 1961, 'Notes on Certain Aspects of the Regulations'. An additional source of information on the Regulations, providing advice on 'how' the user should comply with them which could be augmented from time to time in the light of latest experience, was provided by the Agency, initially in relation to the 1973 edition of the Regulations. This was entitled 'Advisory Material for the IAEA Regulations for the Safe Transport of Radioactive Material' and designated Safety Series No. 37. This document is the result of combining the two Safety Series in a single publication. Thus the primary purpose of this publication is to provide guidance to users on proven and acceptable ways of complying with the Regulations. This Advisory Material is not a stand-alone text and it only has significance when used as a companion to the IAEA Safety Standards Series No. ST-1, Regulations for the Safe Transport of Radioactive Material (1996 edition)

  14. Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets

    Directory of Open Access Journals (Sweden)

    Quagliariello Carla

    2008-03-01

    Full Text Available Abstract Background In plant mitochondria, the post-transcriptional RNA editing process converts C to U at a number of specific sites of the mRNA sequence and usually restores phylogenetically conserved codons and the encoded amino acid residues. Sites undergoing RNA editing evolve at a higher rate than sites not modified by the process. As a result, editing sites strongly affect the evolution of plant mitochondrial genomes, representing an important source of sequence variability and potentially informative characters. To date no clear and convincing evidence has established whether or not editing sites really affect the topology of reconstructed phylogenetic trees. For this reason, we investigated here the effect of RNA editing on the tree building process of twenty different plant mitochondrial gene sequences and by means of computer simulations. Results Based on our simulation study we suggest that the editing ‘noise’ in tree topology inference is mainly manifested at the cDNA level. In particular, editing sites tend to confuse tree topologies when artificial genomic and cDNA sequences are generated shorter than 500 bp and with an editing percentage higher than 5.0%. Similar results have been also obtained with genuine plant mitochondrial genes. In this latter instance, indeed, the topology incongruence increases when the editing percentage goes up from about 3.0 to 14.0%. However, when the average gene length is higher than 1,000 bp (rps3, matR and atp1 no differences in the comparison between inferred genomic and cDNA topologies could be detected. Conclusions Our findings by the here reported in silico and in vivo computer simulation system seem to strongly suggest that editing sites contribute in the generation of misleading phylogenetic trees if the analyzed mitochondrial gene sequence is highly edited (higher than 3.0% and reduced in length (shorter than 500 bp. In the current lack of direct experimental evidence the results

  15. Neurosurgery. Fourth edition

    International Nuclear Information System (INIS)

    Simon, L.; Thomas, D.G.T.; Clark, W.K.

    1987-01-01

    The Fourth Edition of this volume in the Operative Surgery Series has been considerably revised to accommodate the many changes which have changed the practice of neurosurgery in the past eight years. There have been advances in technology, such as the wider application of CT scanning, in surgical technique, and in the design of new implantable materials. All these developments have substantially affected both the practice of neurosurgery and the prognosis for the patient and are fully reflected in the new edition

  16. Strengthening the safety of radiation sources and the security of radioactive materials: Timely action

    International Nuclear Information System (INIS)

    Gonzalez, A.J.

    1999-01-01

    When used as they should be, commercial radiation sources and radioactive materials are useful tools that pose no unacceptable risks to people or environment. In fact, their applications in fields such as medicine, industry, agriculture, and environmental research help countries to achieve sizeable social and economic benefits important to global goals of sustainable development. For most of the past half century, the IAEA has been instrumental in advancing the application of techniques that constructively make use of ionizing radiation properties, particularly in developing countries. But though global standards are in place, and being strengthened, a disturbing picture is emerging. It is regrettably framed by tragic consequences from accidents that involved unsafe, abandoned, lost, or uncontrolled radiation sources, including illicit trafficking of radioactive materials, notably in the 1990s. A turning point in global awareness of serious problems came in 1998, at an international conference in France. In March 1999, the IAEA Board of Governors discussed the issue, and a multi faced Action Plan is being submitted to the general Conference. This edition of IAEA Bulletin looks closely at the problems and issues the international community is facing, and the steps States are taking to reinforce the safety and security of radioactive materials

  17. A Guided Tour of Mathematical Methods - 2nd Edition

    Science.gov (United States)

    Snieder, Roel

    2004-09-01

    Mathematical methods are essential tools for all physical scientists. This second edition provides a comprehensive tour of the mathematical knowledge and techniques that are needed by students in this area. In contrast to more traditional textbooks, all the material is presented in the form of problems. Within these problems the basic mathematical theory and its physical applications are well integrated. The mathematical insights that the student acquires are therefore driven by their physical insight. Topics that are covered include vector calculus, linear algebra, Fourier analysis, scale analysis, complex integration, Green's functions, normal modes, tensor calculus, and perturbation theory. The second edition contains new chapters on dimensional analysis, variational calculus, and the asymptotic evaluation of integrals. This book can be used by undergraduates, and lower-level graduate students in the physical sciences. It can serve as a stand-alone text, or as a source of problems and examples to complement other textbooks. All the material is presented in the form of problems Mathematical insights are gained by getting the reader to develop answers themselves Many applications of the mathematics are given

  18. RCC-MX (2008 edition)

    International Nuclear Information System (INIS)

    Bravo, X.; Drubay, B.

    2008-10-01

    The RCC-MX books is a compilation of design and construction rules for the mechanical materials of experimental reactors, for their auxiliaries and irradiation devices. This second edition includes the updates of references to NF, EN and ISO standards, the compliance with the regulations for nuclear pressure equipments, and the feedback since the 2005 edition. It comprises 9 books and a CD-Rom and includes a presentation document. The RCC-MX has been developed for the Jules Horowitz reactor but can be used for the design and construction of new projects of new experimental reactors or new equipments and devices for existing facilities. Content: - Book 1: general dispositions, materials for experimental reactors and their auxiliaries, for irradiation devices and for control or handling mechanisms, complementary requirements and particular dispositions; - Book 2: materials for the reactor and for its level 1 auxiliaries; - Book 3: materials for the reactor and for its level 2 and level 3 auxiliaries, control and handling mechanisms, materials for irradiation devices; - Book 4: technical appendixes - materials characteristics (steels and alloys); - Book 5: technical appendixes (design rules); - Book 6: technical specifications of materials; - Book 7: tests and control methods; - Book 8: welding; - Book 9: fabrication. (J.S.)

  19. Security of radioactive sources and materials

    International Nuclear Information System (INIS)

    Rodriguez, C.; D'Amato, E.; Fernandez Moreno, S.

    1998-01-01

    The activities involving the use of radiation sources and radioactive materials are subject to the control of the national bodies dedicated to the nuclear regulation. The main objective of this control is to assure an appropriate level of radiological protection and nuclear safety. In Argentina, this function is carried out by the 'Nuclear Regulatory Authority' (ARN) whose regulatory system for radiation sources and radioactive materials comprises a registration, licensing and inspection scheme. The system is designed to keep track of such materials and to allow taking immediate corrective actions in case some incident occurs. Due to the appearance of a considerable number of illicit traffic events involving radiation sources and radioactive materials, the specialized national and international community has begun to evaluate the adoption of supplementary measures to those of 'safety' guided to its prevention and detection (i.e. 'security measures'). This paper presents a view on when the adoption of complementary 'security' measures to those of 'safety' would be advisable and which they would be. This will be done through the analysis of two hypothesis of illicit traffic, the first one with sources and radioactive materials considered as 'registered' and the second, with the same materials designated as 'not registered'. It will also describe succinctly the measures adopted by the ARN or under its analysis regarding the 'security' measures to sources and radioactive materials. (author)

  20. Materials for spallation neutron sources

    International Nuclear Information System (INIS)

    Sommer, W.F.; Daemen, L.L.

    1996-03-01

    The Workshop on Materials for Spallation Neutron Sources at the Los Alamos Neutron Science Center, February 6 to 10, 1995, gathered scientists from Department of Energy national laboratories, other federal institutions, universities, and industry to discuss areas in which work is needed, successful designs and use of materials, and opportunities for further studies. During the first day of the workshop, speakers presented overviews of current spallation neutron sources. During the next 3 days, seven panels allowed speakers to present information on a variety of topics ranging from experimental and theoretical considerations on radiation damage to materials safety issues. An attempt was made to identify specific problems that require attention within the context of spallation neutron sources. This proceedings is a collection of summaries from the overview sessions and the panel presentations

  1. William Gowers: the never completed third edition of the 'Bible of Neurology'.

    Science.gov (United States)

    Eadie, Mervyn J; Scott, Ann E M; Lees, Andrew J; Woodward, Martin

    2012-10-01

    William Gowers' classic single-authored two-volume A manual of diseases of the nervous system appeared in a first edition in 1886 and 1888, and in a second edition in 1892 and 1893, with a third edition of Volume 1 in 1899. No third edition of Volume 2 ever appeared. However, in 1949 Critchley stated that he had seen part of a revision of this volume. Subsequent writers could not find this material, but it recently came to light at Gowers' old hospital at Queen Square, London. The present paper describes the rediscovered material, containing Gowers' handwritten alterations for a further edition of Volume 2, and substantial new material, at least in relation to nystagmus and myasthenia. Gowers' declining health, or a conflict between his planned new text and his contributions to the neurology segments (1899) of Allbutt's System of medicine, may explain why a third edition of Volume 2 of the Manual of diseases of the nervous system never appeared.

  2. Regulations for the safe transport of radioactive material. 1996 edition (revised)

    International Nuclear Information System (INIS)

    2000-01-01

    Following a comprehensive review by panels of experts convened by the IAEA starting in 1991, a revised version of the IAEA Regulations for the Safe Transport of Radioactive Material (formerly Safety Series No. 6) was approved by the Board of Governors in September 1996. This publication supersedes all editions of the Regulations issued under Safety Series No. 6. By 1969, the Regulations had been adopted by almost all international organizations concerned with transport and used by many Member States for their own regulations. Through the worldwide adoption of the IAEA Regulations for all modes of transport, a very high standard of safety in transport has been achieved. In the revisions since the first edition, attempts have been made to find a balance between the need to take account of technical advances and operational experience, and the desirability of providing a stable framework of regulatory requirements. One of the aims of this approach is to allow packages designed to previous versions of the Regulations to continue to be used for a reasonable period of time. It is recognized that not all regulatory changes can be implemented simultaneously; Member States and international organizations are therefore invited, in adopting this revision, to provide for use of both the 'old' requirements and the 'new' ones during a period of transition that may last for a few years. It is further recommended that adoption of these revised Regulations occur within a period of five years from publication to achieve worldwide harmonization of their application. In implementing the provisions of these Regulations, it may be necessary for Member States to issue complementary national regulations. Except as necessary for solely domestic purposes, such national regulations should not conflict with these Regulations. For convenience, the requirements to be met for the transport of specified types of consignments are included in an abbreviated form as Schedules in this publication

  3. Regulations for the safe transport of radioactive material. 1996 edition (revised)

    International Nuclear Information System (INIS)

    2002-01-01

    Following a comprehensive review by panels of experts convened by the IAEA starting in 1991, a revised version of the IAEA Regulations for the Safe Transport of Radioactive Material (formerly Safety Series No. 6) was approved by the Board of Governors in September 1996. This publication supersedes all editions of the Regulations issued under Safety Series No. 6. By 1969, the Regulations had been adopted by almost all international organizations concerned with transport and used by many Member States for their own regulations. Through the worldwide adoption of the IAEA Regulations for all modes of transport, a very high standard of safety in transport has been achieved. In the revisions since the first edition, attempts have been made to find a balance between the need to take account of technical advances and operational experience, and the desirability of providing a stable framework of regulatory requirements. One of the aims of this approach is to allow packages designed to previous versions of the Regulations to continue to be used for a reasonable period of time. It is recognized that not all regulatory changes can be implemented simultaneously. Member States and international organizations are therefore invited, in adopting this revision, to provide for use of both the 'old' requirements and the 'new' ones during a period of transition that may last for a few years. It is further recommended that adoption of these revised Regulations occur within a period of five years from publication to achieve worldwide harmonization of their application. In implementing the provisions of these Regulations, it may be necessary for Member States to issue complementary national regulations. Except as necessary for solely domestic purposes, such national regulations should not conflict with these Regulations. For convenience, the requirements to be met for the transport of specified types of consignments are included in an abbreviated form as Schedules in this publication

  4. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 1995 edition

    International Nuclear Information System (INIS)

    1995-09-01

    This is the sixth annual report being published by the Secretariat of the International Atomic Energy Agency since implementing its database on package approval certificates (PACKTRAM) at the recommendation of the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM). The reporting format was established at consecutive meetings of SAGSTRAM, whose membership consists of national competent authorities responsible for the transport of radioactive material from those Member States who have a nuclear industry and others who have shown a keen interest in the IAEA's transport safety programme. Through the PACKTRAM database, the Secretariat collects administrative and technical information on package approval certificates to assist national competent authorities in regulating radioactive material movements in their country. The database carries information on extant certificates and those that expired within the last complete calendar year. The 1985 Edition of IAEA Safety Series No. 6, the ''Regulations for the Safe Transport of Radioactive Material'' highlights the role of competent authorities in assuring regulatory compliance in their own countries. Package approval certificates are an important aspect of that function. This document aims to be a useful reference for competent authorities as well as for manufacturers and shippers of radioactive material. 6 tabs

  5. Arrangements for transition from the 1985 edition (as amended 1990) to the 1996 edition of the IAEA Transport Regulations

    International Nuclear Information System (INIS)

    2001-03-01

    The purpose of this publication is to provide guidance to National Competent Authorities to facilitate compliance during, and after, transition from the previous edition of the International Atomic Energy Agency's (IAEA's) Transport Regulations (Safety Series No. 6, 1985 Edition, as Amended 1990) to the 1996 editions (TS-R-1 [ST-1, Revised], in English; ST-1 in French, Russian and Spanish) of the regulations. This may also provide guidance to other users of the IAEA's Transport Regulations such as consignors, carriers, consignees, owners and designers and fabricators of radioactive material and package designers and fabrications

  6. Pi a source book

    CERN Document Server

    Berggren, Lennart; Borwein, Peter

    2004-01-01

    This book documents the history of pi from the dawn of mathematical time to the present. One of the beauties of the literature on pi is that it allows for the inclusion of very modern, yet accessible, mathematics. The articles on pi collected herein include selections from the mathematical and computational literature over four millennia, a variety of historical studies on the cultural significance of the number, and an assortment of anecdotal, fanciful, and simply amusing pieces. For this new edition, the authors have updated the original material while adding new material of historical and cultural interest. There is a substantial exposition of the recent history of the computation of digits of pi, a discussion of the normality of the distribution of the digits, new translations of works by Viete and Huygen, as well as Kaplansky's never-before-published "Song of Pi." From the reviews of earlier editions: "Few mathematics books serve a wider potential readership than does a source book and this particular on...

  7. Wearable energy sources based on 2D materials.

    Science.gov (United States)

    Yi, Fang; Ren, Huaying; Shan, Jingyuan; Sun, Xiao; Wei, Di; Liu, Zhongfan

    2018-05-08

    Wearable energy sources are in urgent demand due to the rapid development of wearable electronics. Besides flexibility and ultrathin thickness, emerging 2D materials present certain extraordinary properties that surpass the properties of conventional materials, which make them advantageous for high-performance wearable energy sources. Here, we provide a comprehensive review of recent advances in 2D material based wearable energy sources including wearable batteries, supercapacitors, and different types of energy harvesters. The crucial roles of 2D materials in the wearable energy sources are highlighted. Based on the current progress, the existing challenges and future prospects are outlined and discussed.

  8. Materials Chemistry

    CERN Document Server

    Fahlman, Bradley D

    2011-01-01

    The 2nd edition of Materials Chemistry builds on the strengths that were recognized by a 2008 Textbook Excellence Award from the Text and Academic Authors Association (TAA). Materials Chemistry addresses inorganic-, organic-, and nano-based materials from a structure vs. property treatment, providing a suitable breadth and depth coverage of the rapidly evolving materials field. The 2nd edition continues to offer innovative coverage and practical perspective throughout. After briefly defining materials chemistry and its history, seven chapters discuss solid-state chemistry, metals, semiconducting materials, organic "soft" materials, nanomaterials, and materials characterization. All chapters have been thoroughly updated and expanded with, for example, new sections on ‘soft lithographic’ patterning, ‘click chemistry’ polymerization, nanotoxicity, graphene, as well as many biomaterials applications. The polymer and ‘soft’ materials chapter represents the largest expansion for the 2nd edition. Each ch...

  9. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 1997 Edition

    International Nuclear Information System (INIS)

    1997-08-01

    This is the eighth annual report being published by the Secretariat of the International Atomic Energy Agency since implementing its database on package approval certificates (PACKTRAM) at the recommendation of the then Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM). The functions of SAGSTRAM were taken over in 1996 by the Transport Safety Standards Advisory Committee (TRANSSAC). The reporting format was established at consecutive meetings of SAGSTRAM, whose membership consisted of national competent authorities responsible for the transport of radioactive material from those Member States who have a nuclear industry and others who showed a keen interest in the IAEA's transport safety programme. TRANSSAC underscores the importance of data collecting activities and recommends the continued publication of this annual report. The 1985 Edition of Safety Series No. 6, the ''Regulations for the Safe Transport of Radioactive Material'', highlights the role of competent authorities in assuring regulatory compliance in their own countries. The issuance of package approval certificates is an important aspects of that function. This document aims to be a useful reference for competent authorities as well as for manufacturers and shippers of radioactive material. 6 tabs

  10. Directory of national competent authorities` approval certificates for package design, special form material and shipment of radioactive material. 1995 edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This is the sixth annual report being published by the Secretariat of the International Atomic Energy Agency since implementing its database on package approval certificates (PACKTRAM) at the recommendation of the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM). The reporting format was established at consecutive meetings of SAGSTRAM, whose membership consists of national competent authorities responsible for the transport of radioactive material from those Member States who have a nuclear industry and others who have shown a keen interest in the IAEA`s transport safety programme. Through the PACKTRAM database, the Secretariat collects administrative and technical information on package approval certificates to assist national competent authorities in regulating radioactive material movements in their country. The database carries information on extant certificates and those that expired within the last complete calendar year. The 1985 Edition of IAEA Safety Series No. 6, the ``Regulations for the Safe Transport of Radioactive Material`` highlights the role of competent authorities in assuring regulatory compliance in their own countries. Package approval certificates are an important aspect of that function. This document aims to be a useful reference for competent authorities as well as for manufacturers and shippers of radioactive material. 6 tabs.

  11. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 1999 Edition

    International Nuclear Information System (INIS)

    1999-08-01

    This is the tenth annual report being published by the Secretariat of the International Atomic Energy Agency since implementing its database on package approval certificates (PACKTRAM) at the recommendation of the Transport Safety Standards Advisory Committee (TRANSSAC), formerly known as the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM). The reporting format was established at consecutive meetings of SAGSTRAM and endorsed by TRANSSAC, whose membership consists of national competent authorities responsible for the transport of radioactive material from those Member States who have a nuclear industry and others who have shown a keen interest in the IAEA's transport safety programme. Through the PACKTRAM database, the Secretariat collects administrative and technical information on package approval certificates to assist national competent authorities in regulating radioactive material movements in their country. The database carries information on extant certificates and those that expired within the last complete calendar year. The 1985 Edition of IAEA Safety Series No. 6, the 'Regulations for the Safe Transport of Radioactive Material' highlights the role of competent authorities in assuring regulatory compliance in their own countries. Package approval certificates are an important aspect of that function. This document aims to be a useful reference for competent authorities as well as for manufacturers and shippers of radioactive material

  12. Air Pollution Manual, Part 1--Evaluation. Second Edition.

    Science.gov (United States)

    Giever, Paul M., Ed.

    Due to the great increase in technical knowledge and improvement in procedures, this second edition has been prepared to update existing information. Air pollution legislation is reviewed. Sources of air pollution are examined extensively. They are treated in terms of natural sources, man-made sources, metropolitan regional emissions, emission…

  13. Accelerator-driven neutron sources for materials research

    International Nuclear Information System (INIS)

    Jameson, R.A.

    1990-01-01

    Particle accelerators are important tools for materials research and production. Advances in high-intensity linear accelerator technology make it possible to consider enhanced neutron sources for fusion material studies or as a source of spallation neutrons. Energy variability, uniformity of target dose distribution, target bombardment from multiple directions, time-scheduled dose patterns, and other features can be provided, opening new experimental opportunities. New designs have also been used to ensure hands-on maintenance on the accelerator in these factory-type facilities. Designs suitable for proposals such as the Japanese Energy-Selective Intense Neutron Source, and the international Fusion Materials Irradiation Facility are discussed

  14. Advisory material for the IAEA Regulations for the safe transport of radioactive material (1985 Edition). 3. ed.

    International Nuclear Information System (INIS)

    1987-01-01

    The purpose of this document is to provide advice on the application of the provisions of the 1985 Edition of Safety Series No. 6 (concerning the IAEA Regulations for the Safe Transport of Radioactive Material) in order to help achieve compliance with the regulatory standards. This document also reflects the corrections and changes implemented by the 1986 Supplement to the Regulations for the Safe Transport of Radioactive Material. Its intent is to describe methods, techniques and practices (citing any appropriate national and international standards) which can be considered a means of satisfying certain requirements. It should always be read as offering 'a way' or 'ways' rather than 'the unique way' of achieving compliance. The information provided is to be considered purely advisory and never mandatory, except where a competent authority may require use of any part or parts of the text. This document provides information about the technical requirements of the Regulations and about the methods and technology which may be employed to satisfy them, for the benefit of designers and manufacturers of packagings, consignors, carriers, competent authorities and others, i.e. it provides 'how' information

  15. Guidance on the Import and Export of Radioactive Sources. 2012 Edition

    International Nuclear Information System (INIS)

    2012-05-01

    The IAEA Code of Conduct on the Safety and Security of Radioactive Sources, published as IAEA/CODEOC/2004 in January 2004, provides guidance on how States can safely and securely manage radioactive sources that may pose a significant risk. The concept of such an international undertaking on the safety and security of radioactive sources was highlighted in the major findings of the International Conference on the Safety of Radiation Sources and Security of Radioactive Materials held in Dijon, France, in September 1998. Following that conference, the IAEA Board of Governors requested the Director General to initiate exploratory discussions relating to an international undertaking in the areas of the safety and security of radiation sources. This request was reflected in an Action Plan on the Safety of Radiation Sources and Security of Radioactive Materials, with the Secretariat organizing a series of open-ended meetings of technical and legal experts nominated by Member States to further explore the concept of such an undertaking. Noting comments made during meetings of the Board of Governors, the experts agreed that any international undertaking should, for the present, be in the form of a 'code of conduct'. The text of a Code of Conduct on the Safety and Security of Radioactive Sources was accordingly developed. Steps to strengthen the provisions of the Code were subsequently initiated following the International Conference of National Regulatory Authorities with Competence in the Safety of Radiation Sources and the Security of Radioactive Material held in Buenos Aires in December 2000. Moreover, growing international concern about the security of radioactive sources after the events of 11 September 2001 led to a number of issues being considered further by technical and legal experts. Furthermore, the International Conference on Security of Radioactive Sources held in Vienna in March 2003 made recommendations regarding additional actions that might be needed. In

  16. Regulations for the safe transport of radioactive materials. 1973 revised edition (as amended).

    International Nuclear Information System (INIS)

    1979-01-01

    On the basis of a comprehensive review carried out by a panel of experts, a revised version of the International Atomic Energy Agency's Regulations for the Safe Transport of Radioactive Materials was approved by the Board of Governors in September 1972 and published in April 1973 as Safety Series No.6 - 1973 Revised Edition. Minor amendments, together with a number of changes of detail were promulgated by the Director General in 1975 and 1977. In October 1978, the Standing Advisory Group on the Safe Transport of Radioactive Materials, established by the Director General in 1977, reviewed and recommended a small number of additional amendments. The recommendations of SAGSTRAM were subsequently accepted by the Director General. All these minor amendments and changes of detail are incorporated in the present text of the Regulations. The purpose of these Regulations is to establish standards of safety which provide an acceptable level of control of the radiation hazards to persons, property and the environment that are associated with the transport of radioactive material. They apply to the transport by land, water or air, including transport on own account, of radioactive material other than that which is an integral part of the means of transport. Transport includes any operation incidental to the whole course of carriage, such as loading, unloading and storage in transit. The term includes both normal transport and that under accident conditions

  17. Fan edits and the legacy of The Phantom Edit

    Directory of Open Access Journals (Sweden)

    Joshua Wille

    2014-09-01

    Full Text Available A fan edit can generally be defined as an alternative version of a film or television text created by a fan. It offers a different viewing experience, much as a song remix offers a different listening experience. The contemporary wave of fan edits has emerged during the remix zeitgeist of digital media and at a time when digital video editing technology has become more affordable and popular. The increasing number of alternative versions of films and the works of revisionist Hollywood filmmakers such as George Lucas have contributed to a greater public understanding of cinema as a fluid medium instead of one that exists in a fixed form. The Phantom Edit (2000, a seminal fan edit based on Lucas's Star Wars Episode I: The Phantom Menace (1999, inspired new ranks of fan editors. However, critics have misunderstood fan edits as merely the work of disgruntled fans. In order to provide a critical and historical basis for studies in fan editing as a creative practice, I examine previous interpretations of fan edits in the context of relevant contemporary works, and I use an annotated chronology of The Phantom Edit to trace its influence on subsequent fan editing communities and uncover their relationship with intellectual property disputes.

  18. Electrodeless light source provided with radioactive material

    International Nuclear Information System (INIS)

    1979-01-01

    Radioactive materials are used to assist in starting a discharge in an electrodeless light source. The radioactive emissions predispose on the inner surface of the lamp envelope loosely bound charges which thereafter assist in initiating discharge. The radioactive material can be enclosed within the lamp envelope in gaseous or non-gaseous form. Preferred materials are krypton 85 and americium 241. In addition, the radioactive material can be dispersed in the lamp envelope material or can be a pellet imbedded in the envelope material. Finally, the radioactive material can be located in the termination fixture. Sources of alpha particles, beta particles, or gamma rays are suitable. Because charges accumulate with time on the inner surface of the lamp envelope, activity levels as low as 10 -8 curie are effective as starting aids. (Auth.)

  19. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 1996 edition

    International Nuclear Information System (INIS)

    1996-09-01

    This is the seventh annual report being published by the Secretariat of the International Atomic Energy Agency since implementing its database on package approval certificated (PACKTRAM) at the recommendation of the then Standing Advisory Group on the Sate Transport of Radioactive Material (SAGSTRAM). The functions of SAGSTRAM were taken over in 1996 by the Transport Safety Standards Advisory Committee (TRANSSAC). The reporting format was established at consecutive meetings of SAGSTRAM, whose membership consists of national competent authorities responsible for the transport of radioactive material from those Member States who have a nuclear industry and others who have shown a keen interest in the IAEA's transport safety programme. Through the PACKTRAM database, the Secretariat collects administrative and technical information on package approval certificates to assist national competent authorities in regulating radioactive material movements in their country. The database carries information on extant certificates and those that expired within the last complete calendar year. The 1985 Edition of IAEA Safety Series No. 6, the ''Regulations for the Safe Transport of Radioactive Material'', highlights the role of competent authorities in assuring regulatory compliance in their own countries. Package approval certificates are an important aspect of that function. This document aims to be a useful reference for competent authorities as well as for manufacturers and shippers of radioactive material. 6 tabs

  20. The regulations concerning refining business of nuclear source material and nuclear fuel materials

    International Nuclear Information System (INIS)

    1979-01-01

    The regulations are provided for under the law for the regulations of nuclear source materials, nuclear fuel materials and reactors and provisions concerning refining business in the enforcement order for the law. The basic concepts and terms are defined, such as: exposure dose, accumulative dose; controlled area; inspected surrounding area and employee. Refining facilities listed in the application for designation shall be classified into clushing and leaching, thickning, refining facilities, storage facilities of nuclear source materials and nuclear fuel materials, disposal facilities of contaminated substances and building for refining, etc. Business program attached to the application shall include expected time of beginning of refining, estimated production amount of nuclear source materials or nuclear fuel materials for the first three years and funds necessary for construction, etc. Records shall be made and kept for particular periods on delivery and storage of nuclear source materials and nuclear fuel materials, control of radiation, maintenance and accidents of refining facilities. Safety securing, application of internationally regulated substances and measures in dangerous situations are stipulated respectively. Exposure dose of employees and other specified matters shall be reported by the refiner yearly to the Director General of Science and Technology Agency and the Minister of International Trade and Industry. (Okada, K.)

  1. Materials for cold neutron sources: Cryogenic and irradiation effects

    International Nuclear Information System (INIS)

    Alexander, D.J.

    1990-01-01

    Materials for the construction of cold neutron sources must satisfy a range of demands. The cryogenic temperature and irradiation create a severe environment. Candidate materials are identified and existing cold sources are briefly surveyed to determine which materials may be used. Aluminum- and magnesium-based alloys are the preferred materials. Existing data for the effects of cryogenic temperature and near-ambient irradiation on the mechanical properties of these alloys are briefly reviewed, and the very limited information on the effects of cryogenic irradiation are outlined. Generating mechanical property data under cold source operating conditions is a daunting prospect. It is clear that the cold source material will be degraded by neutron irradiation, and so the cold source must be designed as a brittle vessel. The continued effective operation of many different cold sources at a number of reactors makes it clear that this can be accomplished. 46 refs., 8 figs., 2 tab

  2. Encyclopedia of Smart Materials, 2 Volume Set

    Science.gov (United States)

    Schwartz, Mel

    2002-03-01

    Smart materials--materials and structures that can impart information about their environment to an observer or monitoring device--are revolutionizing fields as diverse as engineering, optics, and medical technology. Advances in smart materials are impacting disciplines across the scientific and technological landscape. Now, practictioners and researchers have an authoritative source to go to for answers about this emerging new area. Encyclopedia of Smart Materials provides A-to-Z coverage of the entire field of intelligent materials. Discussions of theory, fabrication, processing, applications, and uses of these unique materials are presented here in a collection of concise entries from the world's foremost experts in the field--including scientists, educators and engineers. This encyclopedia is as broad in scope as the technology itself, addressing daily, commercial applications as well as sophisticated units designed to operate in space, underwater, underground, and within the human body. Extensively cross-referenced and generously supplemented with bibliographies and indexes, this book's treatment also broaches the specialized properties and coatings that are required for the use of materials in extreme conditions. Illustrated with photographs, tables, line drawings, and equations, Encyclopedia of Smart Materials is the premier reference for material scientists, chemists, chemical engineers, process engineers, consultants, patent attorneys and students in these areas. An essential resource on the shelves of laboratories, government facilities, and academic libraries. Editor-in-Chief, Mel Schwartz has over forty years of experience with metals, ceramics, and composites, with special expertise in brazing. The holder of five patents, he has authored thirteen books and more than one hundred technical papers and articles. Reach the information you need rapidly and easily with the ONLINE edition of the Encyclopedia of Smart Materials. The online edition delivers all

  3. The Edit Distance as a Measure of Perceived Rhythmic Similarity

    Directory of Open Access Journals (Sweden)

    Olaf Post

    2012-07-01

    Full Text Available The ‘edit distance’ (or ‘Levenshtein distance’ measure of distance between two data sets is defined as the minimum number of editing operations – insertions, deletions, and substitutions – that are required to transform one data set to the other (Orpen and Huron, 1992. This measure of distance has been applied frequently and successfully in music information retrieval, but rarely in predicting human perception of distance. In this study, we investigate the effectiveness of the edit distance as a predictor of perceived rhythmic dissimilarity under simple rhythmic alterations. Approaching rhythms as a set of pulses that are either onsets or silences, we study two types of alterations. The first experiment is designed to test the model’s accuracy for rhythms that are relatively similar; whether rhythmic variations with the same edit distance to a source rhythm are also perceived as relatively similar by human subjects. In addition, we observe whether the salience of an edit operation is affected by its metric placement in the rhythm. Instead of using a rhythm that regularly subdivides a 4/4 meter, our source rhythm is a syncopated 16-pulse rhythm, the son. Results show a high correlation between the predictions by the edit distance model and human similarity judgments (r = 0.87; a higher correlation than for the well-known generative theory of tonal music (r = 0.64. In the second experiment, we seek to assess the accuracy of the edit distance model in predicting relatively dissimilar rhythms. The stimuli used are random permutations of the son’s inter-onset intervals: 3-3-4-2-4. The results again indicate that the edit distance correlates well with the perceived rhythmic dissimilarity judgments of the subjects (r = 0.76. To gain insight in the relationships between the individual rhythms, the results are also presented by means of graphic phylogenetic trees.

  4. Friction material composites copper-metal-free material design perspective

    CERN Document Server

    Sundarkrishnaa, K L

    2015-01-01

    This book examines material composites used in connection with brake friction, their design and safety. To aid in understanding, the essentials of friction are explained. This second edition was extended to include friction material composites without copper, as they offer an environmentally friendlier option. The second edition is intended to support beginners by offering insights into the essentials of friction material composites, helping them to develop a broader understanding of brake friction materials. Friction materials find wide-ranging applications in household and industrial appliances, brake pads for automotive applications, rail brake friction pads and composition brake blocks. This second edition is an introductory volume to a set of related books, and is based on the author’s experience and expertise with various material manufacturers, brake manufacturers, vehicle manufacturers, researchers and testing labs around the world with which the author has been associated for the past 28 years.

  5. LevelMerge: Collaborative Game Level Editing by Merging Labeled Graphs

    OpenAIRE

    Santoni, Christian; Salvati, Gabriele; Tibaldo, Valentina; Pellacini, Fabio

    2016-01-01

    Game level editing is the process of constructing a full game level starting from 3D asset libraries, e.g. 3d models, textures, shaders, scripts. In level editing, designers define the look and behavior of the whole level by placing objects, assigning materials and lighting parameters, setting animations and physics properties and customizing the objects AI and behavior by editing scripts. The heterogeneity of the task usually translates to a workflow where a team of people, experts on separa...

  6. Arrangements for transition from the 1985 edition (as amended 1990) to the 1996 edition of the IAEA Transport Regulations

    International Nuclear Information System (INIS)

    2001-01-01

    In December 1996 the International Atomic Energy Agency published the 1996 Edition of the Regulations for the Safe Transport of Radioactive Material (formerly Safety Series No. 6) in a document called ST-1. That document has served as the basis for revising the UN Committee of Experts Recommendations on the Safe Transport of Dangerous Goods (published in 1999 as ''Model Regulations''), and as the basis for the Class 7 portions of the forthcoming revisions of RID, ADR, IMO (IMDG Code), ICAO (Technical Instructions) and IATA modal dangerous goods regulations. ST-1 was subsequently reviewed and revised with minor editorial corrections, and in 2000, a revised English version of the regulations called TS-R-1 (ST-1, Revised) was published. Difficulties may arise when applying the Regulations during the transition from the 1985 Edition of the Transport Regulations to the 1996 Edition of these regulations. These difficulties come mainly from the differences between the two sets of regulations, e.g. the definition of radioactive material with the new nuclide specific exemption levels, the new values of A 1 /A 2 , the annual dose limits, the related documentation, the labelling requirements for fissile material package, the changes in UN numbers and proper shipping names, the shipment of fissile material by air, etc. This TECDOC is intended to provide guidance on the implementation of changes in the Regulations for the Safe Transport of Radioactive Material. This guidance may be used to facilitate compliance with the Regulations. This guidance is aimed at all users of the regulations including National Competent Authorities, consignors, consignees and carriers

  7. Structural materials for fusion and spallation sources

    International Nuclear Information System (INIS)

    Cottrell, G.A.; Baker, L.J.

    2003-01-01

    Experimental investigation of neutron-induced irradiation damage in structural materials is fundamental to the development of magnetic confinement fusion. Proposals for the testing of candidate materials are described, indicating that a period of at least 10 years will elapse before a suitable high neutron fluence fusion test facility becomes available. In this circumstance, the possibility that neutron spallation sources could be exploited to shorten the time-scale of fusion materials development is attractive. Although fusion displacement and transmutation reaction rates can be replicated in spallation sources, there are significant differences arising from the harder neutron spectra and the presence of energetic protons. These differences, including higher energy PKA, electron heating effects, transmutation rates and pulsing are described and their consequences discussed, together with the concomitant development of theoretical models, needed to understand the effects. It is concluded that spallation source experiments could make a significant contribution to the database required for the validation of theoretical models, and hence reduce the time scale of fusion materials development

  8. How To Help Your Child Choose a Career. New and Revised Edition. Today's Youth and Tomorrow's Careers Edition.

    Science.gov (United States)

    Otto, Luther B.

    This edition of a handbook aimed at helping parents help their children make a career choice has been rewritten and updated. New material begins with the introduction, which provides a rationale for involving parents in their sons' and daughters' career decisions. Other new material includes sections on women and work, minorities and work,…

  9. Application of binomial-edited CPMG to shale characterization.

    Science.gov (United States)

    Washburn, Kathryn E; Birdwell, Justin E

    2014-09-01

    Unconventional shale resources may contain a significant amount of hydrogen in organic solids such as kerogen, but it is not possible to directly detect these solids with many NMR systems. Binomial-edited pulse sequences capitalize on magnetization transfer between solids, semi-solids, and liquids to provide an indirect method of detecting solid organic materials in shales. When the organic solids can be directly measured, binomial-editing helps distinguish between different phases. We applied a binomial-edited CPMG pulse sequence to a range of natural and experimentally-altered shale samples. The most substantial signal loss is seen in shales rich in organic solids while fluids associated with inorganic pores seem essentially unaffected. This suggests that binomial-editing is a potential method for determining fluid locations, solid organic content, and kerogen-bitumen discrimination. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Nuclear reactor engineering: Reactor design basics. Fourth edition, Volume One

    International Nuclear Information System (INIS)

    Glasstone, S.; Sesonske, A.

    1994-01-01

    This new edition of this classic reference combines broad yet in-depth coverage of nuclear engineering principles with practical descriptions of their application in design and operation of nuclear power plants. Extensively updated, the fourth edition includes new material on reactor safety and risk analysis, regulation, fuel management, waste management, and operational aspects of nuclear power. This volume contains the following: energy from nuclear fission; nuclear reactions and radiations; neutron transport; nuclear design basics; nuclear reactor kinetics and control; radiation protection and shielding; and reactor materials

  11. Guide for disposition of radioactive-material sources

    International Nuclear Information System (INIS)

    Taylor, J.M.; Selby, J.M.

    1983-04-01

    This guide has been prepared to assist DOE Energy Technology Centers in disposing of radioactive-material sources. The guide describes the steps and requirements necessary to dispose of unwanted sources. The steps include obtaining approvals, source characterization, source disposition, packaging requirements, and shipment preparation. A flow chart is provided in the guide to assist the user in the necessary sequential steps of source disposition

  12. Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.

    Science.gov (United States)

    Vallecillo-Viejo, Isabel C; Liscovitch-Brauer, Noa; Montiel-Gonzalez, Maria Fernanda; Eisenberg, Eli; Rosenthal, Joshua J C

    2018-01-02

    Site-directed RNA editing (SDRE) is a general strategy for making targeted base changes in RNA molecules. Although the approach is relatively new, several groups, including our own, have been working on its development. The basic strategy has been to couple the catalytic domain of an adenosine (A) to inosine (I) RNA editing enzyme to a guide RNA that is used for targeting. Although highly efficient on-target editing has been reported, off-target events have not been rigorously quantified. In this report we target premature termination codons (PTCs) in messages encoding both a fluorescent reporter protein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein transiently transfected into human epithelial cells. We demonstrate that while on-target editing is efficient, off-target editing is extensive, both within the targeted message and across the entire transcriptome of the transfected cells. By redirecting the editing enzymes from the cytoplasm to the nucleus, off-target editing is reduced without compromising the on-target editing efficiency. The addition of the E488Q mutation to the editing enzymes, a common strategy for increasing on-target editing efficiency, causes a tremendous increase in off-target editing. These results underscore the need to reduce promiscuity in current approaches to SDRE.

  13. Apparatus for radiation source depth determination in a material

    International Nuclear Information System (INIS)

    Campbell, P.J.

    1979-01-01

    An apparatus is disclosed for determining the depth of a radiation source within a body of material utilizing a radiation source holder moving the radiation source within the body. A plurality of switches have contacts that are fixed in relation to the movement of the radiation source within the material. Trigger means activates a particular switch at a preselected depth of the radiation source. Means for indicating the activation of a switch would thus produce a signal as a representative of the depth of the radiation source

  14. Particle Physics, 2nd Edition

    Science.gov (United States)

    Martin, B. R.; Shaw, G.

    1998-01-01

    Particle Physics, Second Edition is a concise and lucid account of the fundamental constituents of matter. The standard model of particle physics is developed carefully and systematically, without heavy mathematical formalism, to make this stimulating subject accessible to undergraduate students. Throughout, the emphasis is on the interpretation of experimental data in terms of the basic properties of quarks and leptons, and extensive use is made of symmetry principles and Feynman diagrams, which are introduced early in the book. The Second Edition brings the book fully up to date, including the discovery of the top quark and the search for the Higgs boson. A final short chapter is devoted to the continuing search for new physics beyond the standard model. Particle Physics, Second Edition features: * A carefully structured and written text to help students understand this exciting and demanding subject. * Many worked examples and problems to aid student learning. Hints for solving the problems are given in an Appendix. * Optional "starred" sections and appendices, containing more specialised and advanced material for the more ambitious reader.

  15. Intense Pulsed Neutron Source: Progress report 1991--1996. 15. Anniversary edition -- Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Marzec, B. [ed.

    1996-05-01

    The 15th Anniversary Edition of the IPNS Progress Report is being published in recognition of the Intense Pulsed Neutron Source`s first 15 years of successful operation as a user facility. To emphasize the importance of this milestone, the authors have made the design and organization of the report significantly different from previous IPNS Progress Reports. This report consists of two volumes. For Volume 1, authors were asked to prepare articles that highlighted recent scientific accomplishments at IPNS, from 1991 to present; to focus on and illustrate the scientific advances achieved through the unique capabilities of neutron studies performed by IPNS users; to report on specific activities or results from an instrument; or to focus on a body of work encompassing different neutron-scattering techniques. Articles were also included on the accelerator system, instrumentation, computing, target, and moderators. A list of published and ``in press` articles in journals, books, and conference proceedings, resulting from work done at IPNS since 1991, was compiled. This list is arranged alphabetically according to first author. Publication references in the articles are listed by last name of first author and year of publication. The IPNS experimental reports received since 1991 are compiled in Volume 2. Experimental reports referenced in the articles are listed by last name of first author, instrument designation, and experiment number.

  16. Intense Pulsed Neutron Source: Progress report 1991--1996. 15. Anniversary edition -- Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    The 15th Anniversary Edition of the IPNS Progress Report is being published in recognition of the Intense Pulsed Neutron Source`s first 15 years of successful operation as a user facility. To emphasize the importance of this milestone, the author shave made the design and organization of the report significantly different from previous IPNS Progress Reports. This report consists of two volumes. For Volume 1, authors were asked to prepare articles that highlighted recent scientific accomplishments at IPNS, from 1991 to present; to focus on and illustrate the scientific advances achieved through the unique capabilities of neutron studies performed by IPNS users; to report on specific activities or results from an instrument; or to focus on a body of work encompassing different neutron-scattering techniques. Articles were also included on the accelerator system, instrumentation, computing, target, and moderators. A list of published and ``in press` articles in journals, books, and conference proceedings, resulting from work done at IPNS since 1991, was compiled. This list is arranged alphabetically according to first author. Publication references in the articles are listed by last name of first author and year of publication. The IPNS experimental reports received since 1991 are compiled in Volume 2. Experimental reports referenced in the articles are listed by last name of first author, instrument designation, and experiment number.

  17. Electronic Warfare Target Location Methods, Second Edition. Edited by Richard A. Poisel, Artech House, 2012; 422 pages. Price: £99.00, ISBN 978-1-60807-523-2

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin

    2013-01-01

    Full Text Available Describing the mathematical development underlying current and classical methods of geolocating electronic systems that are emitting, this newly revised and greatly expanded edition of a classic Artech House book offers practical guidance in electronic warfare target location. The Second Edition features a wealth of additional material including new chapters on time delay estimation, direction finding techniques, and the MUSIC algorithm. This practical resource provides you with critical design information on geolocation algorithms, and establishes the fundamentals of existing algorithms as a launch point for further algorithm development. You gain an in-depth understanding of key target location methods that you can effectively apply to your work in the field. You discover triangulation algorithms that offer a highly efficient way to geolocate targets when the real estate on the sensor systems is adequate to support an antenna array. The book also presents quadratic geolocation techniques that can be implemented with extremely modest antennas — frequently a single dipole or monopole. Moreover, this authoritative volume details methods for geolocating the source of high frequency signals with a single sensor site.

  18. A genome-wide map of hyper-edited RNA reveals numerous new sites

    Science.gov (United States)

    Porath, Hagit T.; Carmi, Shai; Levanon, Erez Y.

    2014-01-01

    Adenosine-to-inosine editing is one of the most frequent post-transcriptional modifications, manifested as A-to-G mismatches when comparing RNA sequences with their source DNA. Recently, a number of RNA-seq data sets have been screened for the presence of A-to-G editing, and hundreds of thousands of editing sites identified. Here we show that existing screens missed the majority of sites by ignoring reads with excessive (‘hyper’) editing that do not easily align to the genome. We show that careful alignment and examination of the unmapped reads in RNA-seq studies reveal numerous new sites, usually many more than originally discovered, and in precisely those regions that are most heavily edited. Specifically, we discover 327,096 new editing sites in the heavily studied Illumina Human BodyMap data and more than double the number of detected sites in several published screens. We also identify thousands of new sites in mouse, rat, opossum and fly. Our results establish that hyper-editing events account for the majority of editing sites. PMID:25158696

  19. Residential and Light Commercial HVAC. Teacher Edition and Student Edition. Second Edition.

    Science.gov (United States)

    Stephenson, David

    This package contains teacher and student editions of a residential and light commercial heating, ventilation, and air conditioning (HVAC) course of study. The teacher edition contains information on the following: using the publication; national competencies; competency profile; related academic and workplace skills list; tools, equipment, and…

  20. Image editing with Adobe Photoshop 6.0.

    Science.gov (United States)

    Caruso, Ronald D; Postel, Gregory C

    2002-01-01

    The authors introduce Photoshop 6.0 for radiologists and demonstrate basic techniques of editing gray-scale cross-sectional images intended for publication and for incorporation into computerized presentations. For basic editing of gray-scale cross-sectional images, the Tools palette and the History/Actions palette pair should be displayed. The History palette may be used to undo a step or series of steps. The Actions palette is a menu of user-defined macros that save time by automating an action or series of actions. Converting an image to 8-bit gray scale is the first editing function. Cropping is the next action. Both decrease file size. Use of the smallest file size necessary for the purpose at hand is recommended. Final file size for gray-scale cross-sectional neuroradiologic images (8-bit, single-layer TIFF [tagged image file format] at 300 pixels per inch) intended for publication varies from about 700 Kbytes to 3 Mbytes. Final file size for incorporation into computerized presentations is about 10-100 Kbytes (8-bit, single-layer, gray-scale, high-quality JPEG [Joint Photographic Experts Group]), depending on source and intended use. Editing and annotating images before they are inserted into presentation software is highly recommended, both for convenience and flexibility. Radiologists should find that image editing can be carried out very rapidly once the basic steps are learned and automated. Copyright RSNA, 2002

  1. Singlet-oxygen therapy. Scientific and methodological materials

    OpenAIRE

    Chukhraiev, N.; Chukhraieva, E.; Gun'ko, M.; Kurik, L.; Lomeiko, S.; Marushko, Y.; Samosyuk, N.; Tkalina, A.; Vladimirov, A.; Unichenko, A.; Zavorotnaya, R.; Zukow, W.

    2018-01-01

    Radomska Szkoła Wyższa w Radomiu MEDICAL INNOVATIVE TECHNOLOGIES SINGLET-OXYGEN THERAPY Scientific and methodological materials 2018 This edition had extended and translated from ukrainian Edited by Chukhraiev N., Vladimirov A., Zukow W. Radom, Kyiv Radomska Szkoła Wyższa w Radomiu MEDICAL INNOVATIVE TECHNOLOGIES SINGLET-OXYGEN THERAPY Scientific and methodological materials 2018 This edition had extended and translated from ukrainian Edited by ...

  2. Transportation Energy Data Book: Edition 36

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Susan E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-12-01

    The Transportation Energy Data Book: Edition 36 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 – energy; Chapter 3 – highway vehicles; Chapter 4 – light vehicles; Chapter 5 – heavy vehicles; Chapter 6 – alternative fuel vehicles; Chapter 7 – fleet vehicles; Chapter 8 – household vehicles; Chapter 9 – nonhighway modes; Chapter 10 – transportation and the economy; Chapter 11 – greenhouse gas emissions; and Chapter 12 – criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms is also included for the reader’s convenience.

  3. Transportation Energy Data Book: Edition 35

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Williams, Susan E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-10-01

    The Transportation Energy Data Book: Edition 35 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  4. Transportation Energy Data Book: Edition 23

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.C.

    2003-10-24

    The ''Transportation Energy Data Book: Edition 23'' is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www-cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2--energy; Chapter 3--highway vehicles; Chapter 4--light vehicles; Chapter 5--heavy vehicles; Chapter 6--alternative fuel vehicles; Chapter 7--fleet vehicles; Chapter 8--household vehicles; and Chapter 9--nonhighway modes; Chapter 10--transportation and the economy; Chapter 11--greenhouse gas emissions; and Chapter 12--criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  5. Transportation Energy Data Book (Edition 20)

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.C.

    2000-10-09

    The ''Transportation Energy Data Book: Edition 20'' is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Transportation Technologies in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www-cta.ornl.gov/data/tedb.htm). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2--energy; Chapter 3--greenhouse gas emissions; Chapter 4--criteria pollutant emissions; Chapter 5--transportation and the economy; Chapter 6--highway vehicles; Chapter 7--light vehicles; Chapter 8--heavy vehicles; Chapter 9--alternative fuel vehicles; Chapter 10--fleet vehicles; Chapter 11--household vehicles; and Chapter 12--nonhighway modes. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  6. Transportation Energy Data Book: Edition 21

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.C.

    2001-09-13

    The ''Transportation Energy Data Book: Edition 21'' is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Transportation Technologies in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www-cta.ornl.gov/data/tedb.htm). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2--energy; Chapter 3--greenhouse gas emissions; Chapter 4--criteria pollutant emissions; Chapter 5--transportation and the economy; Chapter 6--highway vehicles; Chapter 7--light vehicles; Chapter 8--heavy vehicles; Chapter 9--alternative fuel vehicles; Chapter 10--fleet vehicles; Chapter 11--household vehicles; and Chapter 12--nonhighway modes. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  7. Transportation Energy Data Book: Edition 24

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.C.

    2005-03-08

    The ''Transportation Energy Data Book: Edition 24'' is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2--energy; Chapter 3--highway vehicles; Chapter 4--light vehicles; Chapter 5--heavy vehicles; Chapter 6--alternative fuel vehicles; Chapter 7--fleet vehicles; Chapter 8--household vehicles; and Chapter 9--nonhighway modes; Chapter 10--transportation and the economy; Chapter 11--greenhouse gas emissions; and Chapter 12--criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  8. Transportation Energy Data Book: Edition 29

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2010-07-01

    The Transportation Energy Data Book: Edition 29 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  9. Transportation Energy Data Book: Edition 28

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2009-06-01

    The Transportation Energy Data Book: Edition 28 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with U.S Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program and the Hydrogen, Fuel Cells, and Infrastructure Technologies Program. Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; and Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  10. Transportation Energy Data Book: Edition 30

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2011-07-01

    The Transportation Energy Data Book: Edition 30 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  11. Transportation Energy Data Book: Edition 31

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2012-08-01

    The Transportation Energy Data Book: Edition 31 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Program. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  12. Transportation Energy Data Book: Edition 27

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2008-06-01

    The Transportation Energy Data Book: Edition 27 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; and Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  13. Transportation Energy Data Book: Edition 26

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL

    2007-07-01

    The Transportation Energy Data Book: Edition 26 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy; Chapter 3 - highway vehicles; Chapter 4 - light vehicles; Chapter 5 - heavy vehicles; Chapter 6 - alternative fuel vehicles; Chapter 7 - fleet vehicles; Chapter 8 - household vehicles; and Chapter 9- nonhighway modes; Chapter 10 - transportation and the economy; Chapter 11 - greenhouse gas emissions; and Chapter 12 - criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  14. Transportation Energy Data Book: Edition 25

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL

    2006-06-01

    The Transportation Energy Data Book: Edition 25 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy; Chapter 3 - highway vehicles; Chapter 4 - light vehicles; Chapter 5 - heavy vehicles; Chapter 6 - alternative fuel vehicles; Chapter 7 - fleet vehicles; Chapter 8 - household vehicles; and Chapter 9- nonhighway modes; Chapter 10 - transportation and the economy; Chapter 11 - greenhouse gas emissions; and Chapter 12 - criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  15. Transportation Energy Data Book. Edition 33

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Williams, Susan E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-07-01

    The Transportation Energy Data Book: Edition 33 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  16. Transportation Energy Data Book: Edition 34

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Williams, Susan E [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Roltek, Inc., Clinton, TN (United States)

    2015-08-01

    The Transportation Energy Data Book: Edition 34 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  17. Transportation Energy Data Book: Edition 32

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2013-08-01

    The Transportation Energy Data Book: Edition 32 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Designed for use as a desk-top reference, the Data Book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest edition of the Data Book is available to a larger audience via the Internet (cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 energy; Chapter 3 highway vehicles; Chapter 4 light vehicles; Chapter 5 heavy vehicles; Chapter 6 alternative fuel vehicles; Chapter 7 fleet vehicles; Chapter 8 household vehicles; Chapter 9 nonhighway modes; Chapter 10 transportation and the economy; Chapter 11 greenhouse gas emissions; and Chapter 12 criteria pollutant emissions. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the reader s convenience.

  18. Transportation Energy Data Book: Edition 22

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy C.; Diegel, Susan W.

    2002-12-04

    The Transportation Energy Data Book: Edition 22 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Planning, Budget Formulation, and Analysis, under the Energy Efficiency and Renewable Energy (EERE) program in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www.cta.ornl.gov/data). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy; Chapter 3 - greenhouse gas emissions; Chapter 4 - criteria pollutant emissions; Chapter 5 - transportation and the economy; Chapter 6 - highway vehicles; Chapter 7 - light vehicles; Chapter 8 - heavy vehicles; Chapter 9 - alternative fuel vehicles; Chapter 10 - fleet vehicles; Chapter 11 - household vehicles; and Chapter 12- nonhighway modes. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience.

  19. Improving the readability of online foot and ankle patient education materials.

    Science.gov (United States)

    Sheppard, Evan D; Hyde, Zane; Florence, Mason N; McGwin, Gerald; Kirchner, John S; Ponce, Brent A

    2014-12-01

    Previous studies have shown the need for improving the readability of many patient education materials to increase patient comprehension. This study's purpose was to determine the readability of foot and ankle patient education materials and to determine the extent readability can be improved. We hypothesized that the reading levels would be above the recommended guidelines and that decreasing the sentence length would also decrease the reading level of these patient educational materials. Patient education materials from online public sources were collected. The readability of these articles was assessed by a readability software program. The detailed instructions provided by the National Institutes of Health (NIH) were then used as a guideline for performing edits to help improve the readability of selected articles. The most quantitative guideline, lowering all sentences to less than 15 words, was chosen to show the effect of following the NIH recommendations. The reading levels of the sampled articles were above the sixth to seventh grade recommendations of the NIH. The MedlinePlus website, which is a part of the NIH website, had the lowest reading level (8.1). The articles edited had an average reduction of 1.41 grade levels, with the lowest reduction in the Medline articles of 0.65. Providing detailed instructions to the authors writing these patient education articles and implementing editing techniques based on previous recommendations could lead to an improvement in the readability of patient education materials. This study provides authors of patient education materials with simple editing techniques that will allow for the improvement in the readability of online patient educational materials. The improvement in readability will provide patients with more comprehendible education materials that can strengthen patient awareness of medical problems and treatments. © The Author(s) 2014.

  20. Licenses for possessing and applying radioactive sources, materials, etc

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    Commercial and governmental institutions have been licensed by Dutch authorities to possess and apply radioactive sources, materials, etc. A summary is given and the list is subdivided into a number of sections such as radioactive sources, radioactive materials, X-ray equipment and technetium-generators

  1. Collection of laws and ordinances concerning regulation of atomic energy, 1989 edition. 1989 ed.

    International Nuclear Information System (INIS)

    1989-01-01

    The collection of the laws and ordinances concerning the regulation of atomic energy, 1989 edition, was published by the Nuclear Safety Bureau, Science and Technology Agency. First, the abbreviated expressions of 56 laws and ordinances are shown. The contents are divided into Part 1: Fundamental laws and ordinances, Part 2: Regulation of nuclear source materials, nuclear fuel materials and nuclear reactors, Part 3: Prevention of radiation injuries due to radioactive isotopes and others, and Part 4: Related laws and ordinances. In Part 1, Atomic Energy Fundamental Act, Act of Institution of Atomic Energy Commission and Nuclear Safety Commission of Japan, Law Concerning the Technical Standard for Prevention of Radiation Injuries and 9 others are included. In Part 2, Law Concerning Regulation of Nuclear Source Materials, Nuclear Fuel Materials and Nuclear Reactors and 45 others are included. In Part 3, Law Concerning Prevention of Radiation Injuries Due to Radioisotopes and Others and 25 others are included. In Part 4, Electricity Enterprises Act, Road Transport and Vehicles Act, Ships' Safety Law, Labor Safety and Hygiene Law, Japan Atomic Energy Research Institute Law and 29 others are included. The contents are those as of November 30, 1988. (Kako, I.)

  2. Transportation Energy Data Book: Edition 21; TOPICAL

    International Nuclear Information System (INIS)

    Davis, SC

    2001-01-01

    The Transportation Energy Data Book: Edition 21 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Transportation Technologies in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. The latest editions of the Data Book are available to a larger audience via the Internet (www-cta.ornl.gov/data/tedb.htm). This edition of the Data Book has 12 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2-energy; Chapter 3-greenhouse gas emissions; Chapter 4-criteria pollutant emissions; Chapter 5-transportation and the economy; Chapter 6-highway vehicles; Chapter 7-light vehicles; Chapter 8-heavy vehicles; Chapter 9-alternative fuel vehicles; Chapter 10-fleet vehicles; Chapter 11-household vehicles; and Chapter 12-nonhighway modes. The sources used represent the latest available data. There are also three appendices which include detailed source information for some tables, measures of conversion, and the definition of Census divisions and regions. A glossary of terms and a title index are also included for the readers convenience

  3. Basics of Desktop Publishing. Second Edition.

    Science.gov (United States)

    Beeby, Ellen; Crummett, Jerrie

    This document contains teacher and student materials for a basic course in desktop publishing. Six units of instruction cover the following: (1) introduction to desktop publishing; (2) desktop publishing systems; (3) software; (4) type selection; (5) document design; and (6) layout. The teacher edition contains some or all of the following…

  4. Materials performance experience at spallation neutron sources

    Energy Technology Data Exchange (ETDEWEB)

    Sommer, W.F. [Los Alamos National Laboratory, NM (United States)

    1995-10-01

    There is a growing, but not yet substantial, data base for materials performance at spallation neutron sources. Specially designed experiments using medium energy protons (650 MeV) have been conducted at the Proton Irradiation Experiment (PIREX) facility at the Swiss Nuclear Institute accelerator (SIN). Specially designed experiments using 760-800 MeV copper target have been completed at the Los Alamos Spallation Radiation Effects Facility (LASREF) at Los Alamos Meson Physics Facility (LAMPF). An extensive material testing program was initiated at LASREF in support of the German spallation neutron source (SNQ) project, before it terminated in 1985.

  5. Standard and reference materials for environmental science. Part 1. Technical memo

    Energy Technology Data Exchange (ETDEWEB)

    Cantillo, A.Y.

    1995-11-01

    This is the fourth edition of the catalog of reference materials suited for use in environmental science, originally compiled in 1986 for NOAA, IOC, and UNEP. The catalog lists more than 1200 reference materials from 28 producers and contains information about their proper use, sources, availability, and analyte concentrations. Indices are included for elements, isotopes, and organic compounds, as are cross references to CAS registry numbers, alternate names, and chemical structures of selected organic compounds.

  6. Standard and reference materials for environmental science. Part 2. Technical memo

    Energy Technology Data Exchange (ETDEWEB)

    Cantillo, A.Y.

    1995-11-01

    This is the fourth edition of the catalog of reference materials suited for use in environmental science, originally compiled in 1986 for NOAA, IOC, and UNEP. The catalog lists more than 1200 reference materials from 28 producers and contains information about their proper use, sources, availability, and analyte concentrations. Indices are included for elements, isotopes, and organic compounds, as are cross references to CAS registry numbers, alternate names, and chemical structures of selected organic compounds.

  7. The New Edition of Chopin’s Correspondence

    Directory of Open Access Journals (Sweden)

    Helman-Bednarczyk Zofia

    2016-12-01

    Full Text Available Some of Fryderyk Chopin’s letters were published individually or in groups already in the 2nd half of the 19th century. With the passage of time, more letters from and to Chopin were printed in monographs dedicated to his life and work. The first editions of Chopin’s collected letters come from the 1st half of the 20th century (by Scharlitt and von Guttry in Germany, Henryk Opieński – in Poland. B.E. Sydow’s Fryderyk Chopin’s Correspondence of 1955 continues to be used as the basic source edition by Chopin biographers. It has many strong points, but has become largely outdated.

  8. General edition program

    International Nuclear Information System (INIS)

    Vaturi, Sylvain

    1969-01-01

    Computerized edition is essential for data processing exploitation. When a more or less complex edition program is required for each task, then the need for a general edition program become obvious. The aim of this study is to create a general edition program. Universal programs are capable to execute numerous and varied tasks. For a more precise processing, the execution of which is frequently required, the use of a specialized program is preferable because, contradictory to the universal program, it goes straight to the point [fr

  9. Global Bathymetry: Machine Learning for Data Editing

    Science.gov (United States)

    Sandwell, D. T.; Tea, B.; Freund, Y.

    2017-12-01

    The accuracy of global bathymetry depends primarily on the coverage and accuracy of the sounding data and secondarily on the depth predicted from gravity. A main focus of our research is to add newly-available data to the global compilation. Most data sources have 1-12% of erroneous soundings caused by a wide array of blunders and measurement errors. Over the years we have hand-edited this data using undergraduate employees at UCSD (440 million soundings at 500 m resolution). We are developing a machine learning approach to refine the flagging of the older soundings and provide automated editing of newly-acquired soundings. The approach has three main steps: 1) Combine the sounding data with additional information that may inform the machine learning algorithm. The additional parameters include: depth predicted from gravity; distance to the nearest sounding from other cruises; seafloor age; spreading rate; sediment thickness; and vertical gravity gradient. 2) Use available edit decisions as training data sets for a boosted tree algorithm with a binary logistic objective function and L2 regularization. Initial results with poor quality single beam soundings show that the automated algorithm matches the hand-edited data 89% of the time. The results show that most of the information for detecting outliers comes from predicted depth with secondary contributions from distance to the nearest sounding and longitude. A similar analysis using very high quality multibeam data shows that the automated algorithm matches the hand-edited data 93% of the time. Again, most of the information for detecting outliers comes from predicted depth secondary contributions from distance to the nearest sounding and longitude. 3) The third step in the process is to use the machine learning parameters, derived from the training data, to edit 12 million newly acquired single beam sounding data provided by the National Geospatial-Intelligence Agency. The output of the learning algorithm will be

  10. Measures Against-Illicit Trafficking of Nuclear Materials and Other Radioactive Sources

    International Nuclear Information System (INIS)

    Barakat, M.B.; Nassef, M.H.; El Mongy, S.A.

    2008-01-01

    Since the early nineties, illicit trafficking (IT) of nuclear materials and radioactive sources appeared as a new trend which raised the concern of the international community due to the grave consequences that would merge if these materials or radioactive sources fell into the hands of terrorist groups. However, by the end of the last century illicit trafficking of nuclear materials and radioactive sources lost its considerable salience, in spite of seizure of considerable amounts of 2 '3'5U (76% enrichment) in Bulgaria (May 1999) and also 235 U (30% enrichment) in Georgia (April 2000). Nevertheless, IT should be always considered as a continued and viable threat to the international community. Awareness of the problem should be developed and maintained among concerned circles as the first step towards combating illicit trafficking of nuclear materials and radioactive sources. Illicit trafficking of nuclear and radioactive materials needs serious consideration and proper attention by the governmental law enforcement authorities. Measures to combat with IT of nuclear material or radioactive sources should be effective in recovery, of stolen, removed or lost nuclear materials or radioactive sources due to the failure of the physical protection system or the State System Accounting and Control (SSAC) system which are normally applied for protecting these materials against illegal actions. Measures such as use of modern and efficient radiation monitoring equipment at the borders inspection points, is an important step in preventing the illicit trafficking of nuclear and radioactive materials across the borders. Also providing radiological training to specific personnel and workers in this field will minimize the consequences of a radiological attack in case of its occurrence. There is a real need to start to enter into cooperative agreements to strengthen borders security under the umbrella of IAEA to faster as an international cooperation in the illicit trafficking

  11. Solid material evaporation into an ECR source by laser ablation

    International Nuclear Information System (INIS)

    Harkewicz, R.; Stacy, J.; Greene, J.; Pardo, R.C.

    1993-01-01

    In an effort to explore new methods of producing ion beams from solid materials, we are attempting to develop a laser-ablation technique for evaporating materials directly into an ECR ion source plasma. A pulsed NdYaG laser with approximately 25 watts average power and peak power density on the order of 10 7 W/cm 2 has been used off-line to measure ablation rates of various materials as a function of peak laser power. The benefits anticipated from the successful demonstration of this technique include the ability to use very small quantities of materials efficiently, improved material efficiency of incorporation into the ECR plasma, and decoupling of the material evaporation process from the ECR source tuning operation. Here we report on the results of these tests and describe the design for incorporating such a system directly with the ATLAS PII-ECR ion source

  12. Influence of source geometry and materials on the transverse axis dosimetry of 192Ir brachytherapy sources

    International Nuclear Information System (INIS)

    Wang, Ruqing; Sloboda, Ron S.

    1998-01-01

    Monte Carlo dose rates on the transverse axis in water and air kerma strengths normalized to unit source activity were calculated for a low dose rate steel-clad 192 Ir source, MicroSelectron high dose rate and pulsed dose rate 192 Ir sources, and a VariSource high dose rate 192 Ir source, as well as five other hypothetical cylindrical 192 Ir source designs. Based on these results, the dependence of dose rate and air kerma strength on source geometry and materials was analysed. Source geometry and attenuation in the core material are the important factors determining basic dosimetric characteristics. Core length, h, only affects the dose rate on the transverse axis at radial distances r 192 Ir sources is suggested, and similarities and differences in the dose rate constant and radial dose function between these sources are explained. (author)

  13. Can i just check...? Effects of edit check questions on measurement error and survey estimates

    NARCIS (Netherlands)

    Lugtig, Peter; Jäckle, Annette

    2014-01-01

    Household income is difficult to measure, since it requires the collection of information about all potential income sources for each member of a household.Weassess the effects of two types of edit check questions on measurement error and survey estimates: within-wave edit checks use responses to

  14. Illicit trafficking of nuclear material and other radioactive sources

    International Nuclear Information System (INIS)

    Yilmazer, A.; Yuecel, A.; Yavuz, U.

    2001-01-01

    As it is known, for the fact that the illicit trafficking and trading of nuclear materials are being increased over the past few years because of the huge demand of third world states. Nuclear materials like uranium, plutonium, and thorium are used in nuclear explosives that have very attractive features for crime groups, terrorist groups and, the states that are willing to have this power. Crime groups that make illegal trade of nuclear material are also trying to market strategic radioactive sources like red mercury and Osmium. This kind of illegal trade threats public safety, human health, environment also it brings significant threat on world peace and world public health. For these reasons, both states and international organizations should take a role in dealing with illicit trafficking. An important precondition for preventing this kind of incidents is the existence of a strengthened national system for control of all nuclear materials and other radioactive sources. Further, Governments are responsible for law enforcement within their borders for prevention of illegal trading and trafficking of nuclear materials and radiation sources

  15. Multiplex editing system

    DEFF Research Database (Denmark)

    2015-01-01

    The present invention relates to a multiplex editing system. The system allows multiple editing of nucleic acid sequences such as genomic sequences, such as knockins of genes of interest in a genome, knockouts of genomic sequences and/or allele replacement. Also provided herein are a method...... for editing nucleic acids and a cell comprising a stably integrated endonuclease....

  16. ExpEdit: a webserver to explore human RNA editing in RNA-Seq experiments.

    Science.gov (United States)

    Picardi, Ernesto; D'Antonio, Mattia; Carrabino, Danilo; Castrignanò, Tiziana; Pesole, Graziano

    2011-05-01

    ExpEdit is a web application for assessing RNA editing in human at known or user-specified sites supported by transcript data obtained by RNA-Seq experiments. Mapping data (in SAM/BAM format) or directly sequence reads [in FASTQ/short read archive (SRA) format] can be provided as input to carry out a comparative analysis against a large collection of known editing sites collected in DARNED database as well as other user-provided potentially edited positions. Results are shown as dynamic tables containing University of California, Santa Cruz (UCSC) links for a quick examination of the genomic context. ExpEdit is freely available on the web at http://www.caspur.it/ExpEdit/.

  17. Accelerating fissile material detection with a neutron source

    Science.gov (United States)

    Rowland, Mark S.; Snyderman, Neal J.

    2018-01-30

    A neutron detector system for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly to count neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source. The system includes a Poisson neutron generator for in-beam interrogation of a possible fissile neutron source and a DC power supply that exhibits electrical ripple on the order of less than one part per million. Certain voltage multiplier circuits, such as Cockroft-Walton voltage multipliers, are used to enhance the effective of series resistor-inductor circuits components to reduce the ripple associated with traditional AC rectified, high voltage DC power supplies.

  18. Oxyacetylene Welding and Oxyfuel Cutting. Third Edition. Teacher Edition [and] Student Edition [and] Student Workbook.

    Science.gov (United States)

    Knapp, John; Harper, Eddie

    This Oklahoma curriculum guide, which includes a teacher edition, a student edition, and a student workbook, provides three units for a course on oxyacetylene welding, oxyfuel cutting, and cutting done with alternative fuels such as MAPP, propane, and natural gas. The three units are: "Oxyacetylene Welding"; "Oxyfuel Cutting";…

  19. Smart material-based radiation sources

    Science.gov (United States)

    Kovaleski, Scott

    2014-10-01

    From sensors to power harvesters, the unique properties of smart materials have been exploited in numerous ways to enable new applications and reduce the size of many useful devices. Smart materials are defined as materials whose properties can be changed in a controlled and often reversible fashion by use of external stimuli, such as electric and magnetic fields, temperature, or humidity. Smart materials have been used to make acceleration sensors that are ubiquitous in mobile phones, to make highly accurate frequency standards, to make unprecedentedly small actuators and motors, to seal and reduce friction of rotating shafts, and to generate power by conversion of either kinetic or thermal energy to electrical energy. The number of useful devices enabled by smart materials is large and continues to grow. Smart materials can also be used to generate plasmas and accelerate particles at small scales. The materials discussed in this talk are from non-centrosymmetric crystalline classes including piezoelectric, pyroelectric, and ferroelectric materials, which produce large electric fields in response to external stimuli such as applied electric fields or thermal energy. First, the use of ferroelectric, pyroelectric and piezoelectric materials for plasma generation and particle acceleration will be reviewed. The talk will then focus on the use of piezoelectric materials at the University of Missouri to construct plasma sources and electrostatic accelerators for applications including space propulsion, x-ray imaging, and neutron production. The basic concepts of piezoelectric transformers, which are analogous to conventional magnetic transformers, will be discussed, along with results from experiments over the last decade to produce micro-thrusters for space propulsion and particle accelerators for x-ray and neutron production. Support from ONR, AFOSR, and LANL.

  20. Health Activities Project (HAP), Trial Edition III.

    Science.gov (United States)

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) trial edition (set III) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into an Overview, Health Background, Materials, Setting Up, and…

  1. Source Identification of Human Biological Materials and Its Prospect in Forensic Science.

    Science.gov (United States)

    Zou, K N; Gui, C; Gao, Y; Yang, F; Zhou, H G

    2016-06-01

    Source identification of human biological materials in crime scene plays an important role in reconstructing the crime process. Searching specific genetic markers to identify the source of different human biological materials is the emphasis and difficulty of the research work of legal medical experts in recent years. This paper reviews the genetic markers which are used for identifying the source of human biological materials and studied widely, such as DNA methylation, mRNA, microRNA, microflora and protein, etc. By comparing the principles and methods of source identification of human biological materials using different kinds of genetic markers, different source of human biological material owns suitable marker types and can be identified by detecting single genetic marker or combined multiple genetic markers. Though there is no uniform standard and method for identifying the source of human biological materials in forensic laboratories at present, the research and development of a series of mature and reliable methods for distinguishing different human biological materials play the role as forensic evidence which will be the future development direction. Copyright© by the Editorial Department of Journal of Forensic Medicine.

  2. Licensing authority's control of radiation sources and nuclear materials in Brazil

    International Nuclear Information System (INIS)

    Binns, D.A.C.

    2002-01-01

    Full text: The Brazilian Nuclear Energy Commission is the national licensing authority and among its responsibilities is the control of nuclear materials and radiation sources. This control is carried out in three different ways: 1) Control of the import and export of nuclear materials and radiation sources. To be able to import or export any nuclear material or radiation source, the user has to have an explicit permission of the licensing authority. This is controlled by electronic means in which the user has to fill a special form found on the licensing authority's home page, where he has to fill in his name, license number, license number of his radiation protection officer and data of the material to be imported or exported. These data are checked with a data base that contains all the information of the licensed users and qualified personnel before authorization is emitted. The airport authorities have already installed x-ray machines to check all baggages entering or leaving the country. 2) Transport and transfer permit for radiation sources. In order to transport and/or transfer radiations sources and nuclear materials within the country, the user(s) have to submit an application to the licensing authority. The user(s) fill out an application form where he fills in his company's name, licensing I.D., radiation protection officer's name and I.D and identification of the sources involved. These information are checked with the licensing operations data before the operations is permitted. 3) Inspections and radiation monitoring systems. Routine and regulatory inspections are continuously carried out where the user's radiation sources and nuclear materials inventory are checked. Also the physical security and protection of these materials are verified. The installation of monitoring systems is an item that is being discussed with the airport authorities so as to increase the possibilities of detecting any illegal transport of these materials. (author)

  3. Python Materials Genomics (pymatgen): A robust, open-source python library for materials analysis

    OpenAIRE

    Ong, Shyue Ping; Richards, William Davidson; Jain, Anubhav; Hautier, Geoffroy; Kocher, Michael; Cholia, Shreyas; Gunter, Dan; Chevrier, Vincent L.; Persson, Kristin A.; Ceder, Gerbrand

    2012-01-01

    We present the Python Materials Genomics (pymatgen) library, a robust, open-source Python library for materials analysis. A key enabler in high-throughput computational materials science efforts is a robust set of software tools to perform initial setup for the calculations (e.g., generation of structures and necessary input files) and post-calculation analysis to derive useful material properties from raw calculated data. The pymatgen library aims to meet these needs by (1) defining core Pyt...

  4. A comparison of the first and second editions of the Dictionary of Literary Slovene

    Directory of Open Access Journals (Sweden)

    Simon Krek

    2014-12-01

    Full Text Available The paper investigates the differences between the first and second editions of the Dictionary of Literary Slovene (SSKJ. The analysis is two-fold: first, a detailed comparison of headword lists of both editions is conducted, followed by the comparison of 2,500 entries from both editions, consisting of a hundred entries for each letter. The analysis shows that the spelling and pronunciation changes to the entries in the second edition were made without the approval of any relevant language authority. Also, the changes introduced are random and inconsistent, and are affecting the consistency of lexicographic description of the first edition, especially on the grammatical level. Furthermore, the editorial decision to make identifying the source of lexicographic information (i.e. the first edition of SSKJ or the Dictionary of New Words of the Slovenian language impossible, raises doubts about lexicographic credibility of the second edition as a description of contemporary Slovene. From the lexicographic perspective, it would have been more appropriate to leave the first edition unchanged and the Dictionary of New Words of the Slovenian language as a separate publication. In addition, the second edition of SSKJ is not freely available online, and neither of the editions is freely available in the form of a dictionary database for natural language processing and other uses.

  5. Health Activities Project (HAP), Trial Edition II.

    Science.gov (United States)

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) trial edition (set II) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into a Synopsis, Health Background, Materials, Setting Up, and Activities…

  6. Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing.

    Science.gov (United States)

    Fossat, Nicolas; Tam, Patrick P L

    2014-01-01

    Cytidine (C) to Uridine (U) RNA editing is a post-trancriptional modification that until recently was known to only affect Apolipoprotein b (Apob) RNA and minimally require 2 components of the C to U editosome, the deaminase APOBEC1 and the RNA-binding protein A1CF. Our latest work has identified a novel RNA-binding protein, RBM47, as a core component of the editosome, which can substitute A1CF for the editing of ApoB mRNA. In addition, new RNA species that are subjected to C to U editing have been identified. Here, we highlight these recent discoveries and discuss how they change our view of the composition of the C to U editing machinery and expand our knowledge of the functional attributes of C to U RNA editing.

  7. Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

    Directory of Open Access Journals (Sweden)

    Masfique Mehedi

    Full Text Available Ebolavirus (EBOV, the causative agent of a severe hemorrhagic fever and a biosafety level 4 pathogen, increases its genome coding capacity by producing multiple transcripts encoding for structural and nonstructural glycoproteins from a single gene. This is achieved through RNA editing, during which non-template adenosine residues are incorporated into the EBOV mRNAs at an editing site encoding for 7 adenosine residues. However, the mechanism of EBOV RNA editing is currently not understood. In this study, we report for the first time that minigenomes containing the glycoprotein gene editing site can undergo RNA editing, thereby eliminating the requirement for a biosafety level 4 laboratory to study EBOV RNA editing. Using a newly developed dual-reporter minigenome, we have characterized the mechanism of EBOV RNA editing, and have identified cis-acting sequences that are required for editing, located between 9 nt upstream and 9 nt downstream of the editing site. Moreover, we show that a secondary structure in the upstream cis-acting sequence plays an important role in RNA editing. EBOV RNA editing is glycoprotein gene-specific, as a stretch encoding for 7 adenosine residues located in the viral polymerase gene did not serve as an editing site, most likely due to an absence of the necessary cis-acting sequences. Finally, the EBOV protein VP30 was identified as a trans-acting factor for RNA editing, constituting a novel function for this protein. Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen.

  8. Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

    Science.gov (United States)

    Mehedi, Masfique; Hoenen, Thomas; Robertson, Shelly; Ricklefs, Stacy; Dolan, Michael A; Taylor, Travis; Falzarano, Darryl; Ebihara, Hideki; Porcella, Stephen F; Feldmann, Heinz

    2013-01-01

    Ebolavirus (EBOV), the causative agent of a severe hemorrhagic fever and a biosafety level 4 pathogen, increases its genome coding capacity by producing multiple transcripts encoding for structural and nonstructural glycoproteins from a single gene. This is achieved through RNA editing, during which non-template adenosine residues are incorporated into the EBOV mRNAs at an editing site encoding for 7 adenosine residues. However, the mechanism of EBOV RNA editing is currently not understood. In this study, we report for the first time that minigenomes containing the glycoprotein gene editing site can undergo RNA editing, thereby eliminating the requirement for a biosafety level 4 laboratory to study EBOV RNA editing. Using a newly developed dual-reporter minigenome, we have characterized the mechanism of EBOV RNA editing, and have identified cis-acting sequences that are required for editing, located between 9 nt upstream and 9 nt downstream of the editing site. Moreover, we show that a secondary structure in the upstream cis-acting sequence plays an important role in RNA editing. EBOV RNA editing is glycoprotein gene-specific, as a stretch encoding for 7 adenosine residues located in the viral polymerase gene did not serve as an editing site, most likely due to an absence of the necessary cis-acting sequences. Finally, the EBOV protein VP30 was identified as a trans-acting factor for RNA editing, constituting a novel function for this protein. Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen.

  9. On material and energy sources of formation of fuel-containing materials during Chernobyl NPP UNIT 4 accident

    Directory of Open Access Journals (Sweden)

    O. V. Mikhailov

    2016-12-01

    Full Text Available Results of detailed analysis of material substance of lava-like fuel-containing materials sources (FCM and clusters with high uranium concentration were presented. Material and energy balance are aggregated in a process model for optimal composition of sacrificial materials and FCM. Quantitative estimate is given for spent nuclear fuel’ afterheat in a number of other heat energy sources in reactor vault. Conclusion was made that upon condition of 50 % heat loss, remained amount of “useful” heat would be sufficient for proceeding of blast furnace version of fuel-containing materials.

  10. Understanding Editing Behaviors in Multilingual Wikipedia.

    Science.gov (United States)

    Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H

    2016-01-01

    Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  11. Understanding Editing Behaviors in Multilingual Wikipedia.

    Directory of Open Access Journals (Sweden)

    Suin Kim

    Full Text Available Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  12. Spectrally edited 2D 13Csbnd 13C NMR spectra without diagonal ridge for characterizing 13C-enriched low-temperature carbon materials

    Science.gov (United States)

    Johnson, Robert L.; Anderson, Jason M.; Shanks, Brent H.; Fang, Xiaowen; Hong, Mei; Schmidt-Rohr, Klaus

    2013-09-01

    Two robust combinations of spectral editing techniques with 2D 13Csbnd 13C NMR have been developed for characterizing the aromatic components of 13C-enriched low-temperature carbon materials. One method (exchange with protonated and nonprotonated spectral editing, EXPANSE) selects cross peaks of protonated and nearby nonprotonated carbons, while the other technique, dipolar-dephased double-quantum/single-quantum (DQ/SQ) NMR, selects signals of bonded nonprotonated carbons. Both spectra are free of a diagonal ridge, which has many advantages: Cross peaks on the diagonal or of small intensity can be detected, and residual spinning sidebands or truncation artifacts associated with the diagonal ridge are avoided. In the DQ/SQ experiment, dipolar dephasing of the double-quantum coherence removes protonated-carbon signals; this approach also eliminates the need for high-power proton decoupling. The initial magnetization is generated with minimal fluctuation by combining direct polarization, cross polarization, and equilibration by 13C spin diffusion. The dipolar dephased DQ/SQ spectrum shows signals from all linkages between aromatic rings, including a distinctive peak from polycondensed aromatics. In EXPANSE NMR, signals of protonated carbons are selected in the first spectral dimension by short cross polarization combined with dipolar dephasing difference. This removes ambiguities of peak assignment to overlapping signals of nonprotonated and protonated aromatic carbons, e.g. near 125 ppm. Spin diffusion is enhanced by dipolar-assisted rotational resonance. Before detection, Csbnd H dipolar dephasing by gated decoupling is applied, which selects signals of nonprotonated carbons. Thus, only cross peaks due to magnetization originating from protonated C and ending on nearby nonprotonated C are retained. Combined with the chemical shifts deduced from the cross-peak position, this double spectral editing defines the bonding environment of aromatic, COO, and Cdbnd O carbons

  13. Carbohydrate sources of microfouling material developed on aluminium and stainless steel panels

    Digital Repository Service at National Institute of Oceanography (India)

    Bhosle, N.B.; Sankaran, P.D.; Wagh, A.B.

    . pp. 151 -164 Reprints available directly from the pUblishcr Photocopying permitted by license only © 1990 Harwood Academic Publishers GmbH Printed in Great Britain CARBOHYDRATE SOURCES OF MICROFOULING MATERIAL DEVELOPED ON ALUMINIUM AND STAINLESS... plant material and grasses appear to be the major sources contributing to the carbohydrates ofthe microfouling material. KEY WORDS: Carbohydratc. microfouling. sources, aluminium, stainless steel, Arabian Sea, Bay of Hengal. INTRODUCTION Solid surfaces...

  14. REDIdb: the RNA editing database.

    Science.gov (United States)

    Picardi, Ernesto; Regina, Teresa Maria Rosaria; Brennicke, Axel; Quagliariello, Carla

    2007-01-01

    The RNA Editing Database (REDIdb) is an interactive, web-based database created and designed with the aim to allocate RNA editing events such as substitutions, insertions and deletions occurring in a wide range of organisms. The database contains both fully and partially sequenced DNA molecules for which editing information is available either by experimental inspection (in vitro) or by computational detection (in silico). Each record of REDIdb is organized in a specific flat-file containing a description of the main characteristics of the entry, a feature table with the editing events and related details and a sequence zone with both the genomic sequence and the corresponding edited transcript. REDIdb is a relational database in which the browsing and identification of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA sequences or to show the corresponding alignment. In both cases, all editing sites are highlighted in colour and their relative positions are detailed by mousing over. New editing positions can be directly submitted to REDIdb after a user-specific registration to obtain authorized secure access. This first version of REDIdb database stores 9964 editing events and can be freely queried at http://biologia.unical.it/py_script/search.html.

  15. Safety of radiation sources and other radioactive materials in Jordan

    International Nuclear Information System (INIS)

    Majali, M.M.

    2001-01-01

    Since joining the IAEA Model Project for upgrading radiation protection infrastructure in countries of West Asia, Jordan has amended its radiation safety legislation. The Regulatory Authority is improving its inventory system for radiation sources and other radioactive materials and also its notification, registration, licensing, inspection and enforcement systems. It has established national provisions for the management of orphan sources after they have been found. The system for the control of the radiation sources and other radioactive materials entering the country has been improved by the Regulatory Authority. (author)

  16. Determination of internationally controlled materials according to provisions of the law for the regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1984-01-01

    The internationally controlled materials determined according to the law for nuclear source materials, etc. are the following: nuclear source materials, nuclear fuel materials, moderating materials, facilities including reactors, etc. sold, transferred, etc. to Japan according to the agreements for peaceful uses of atomic energy between Japan, and the United States, the United Kingdom, Canada, Australia and France by the respective governments and those organs under them; nuclear fuel materials resulting from usage of the above sold and transferred materials, facilities; nuclear fuel materials sold to Japan according to agreements set by the International Atomic Energy Agency; nuclear fuel materials involved with the safeguards in nuclear weapons non-proliferation treaty with IAEA. (Mori, K.)

  17. Transportation Energy Data Book, Edition 18

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy C.

    1998-09-01

    The Transportation Energy Data Book: Edition 18 is a statistical compendium prepared and published by Oak Ridge National Laboratory (ORNL) under contract with the Office of Transportation Technologies in the Department of Energy (DOE). Designed for use as a desk-top reference, the data book represents an assembly and display of statistics and information that characterize transportation activity, and presents data on other factors that influence transportation energy use. The purpose of this document is to present relevant statistical data in the form of tables and graphs. This edition of the Data Book has 11 chapters which focus on various aspects of the transportation industry. Chapter 1 focuses on petroleum; Chapter 2 - energy Chapter 3 - emissions; Chapter 4 - transportation and the economy; Chapter 5 - highway vehicles; Chapter 6 - Light vehicles; Chapter 7 - heavy vehicles; Chapter 8 - alternative fuel vehicles; Chapter 9 - fleet vehicles; Chapter 10 - household vehicles; and Chapter 11 - nonhighway modes. The sources used represent the latest available data.

  18. The Materials Science beamline upgrade at the Swiss Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Willmott, P. R., E-mail: philip.willmott@psi.ch; Meister, D.; Leake, S. J.; Lange, M.; Bergamaschi, A. [Swiss Light Source, Paul Scherrer Institut, CH-5232 Villigen (Switzerland); and others

    2013-07-16

    The wiggler X-ray source of the Materials Science beamline at the Swiss Light Source has been replaced with a 14 mm-period cryogenically cooled in-vacuum undulator. In order to best exploit the increased brilliance of this new source, the entire front-end and optics have been redesigned. The Materials Science beamline at the Swiss Light Source has been operational since 2001. In late 2010, the original wiggler source was replaced with a novel insertion device, which allows unprecedented access to high photon energies from an undulator installed in a medium-energy storage ring. In order to best exploit the increased brilliance of this new source, the entire front-end and optics had to be redesigned. In this work, the upgrade of the beamline is described in detail. The tone is didactic, from which it is hoped the reader can adapt the concepts and ideas to his or her needs.

  19. Neutron source characterization for materials experiments

    International Nuclear Information System (INIS)

    Greenwood, L.R.

    1982-01-01

    Data are presented from HFIR-CTR32, EBRII-X287, and the Omega West Reactor. An important new source of damage in nickel arises from the 340 keV 56 Fe recoil from the 59 Ni(n,α) reaction used to produce high helium levels in materials irradiations in a thermal spectrum. The status of all other experiments is summarized

  20. Beyond Author-Centricity in Scholarly Editing

    Directory of Open Access Journals (Sweden)

    Hans Walter Gabler

    2012-03-01

    Full Text Available Authorship – authority – authorisation – the author – the author’s will – the author’s intention: these form a cluster of notions whose validity for scholarly editing I fundamentally question. Taking measure from a historical survey of the discipline’s principles and practice from their institution under the dominance of stemmatics up to their main present-day ‘author orientation’ (Shillingsburg 1996, I see the need to split the terms ‘author’ and ‘authorship’ into a pragmatic versus a conceptual aspect. What textual scholarship engages with, directly and tangibly, is not authors but texts (and equally not works but texts, materially inscribed in transmissions. In the materiality and artifice of texts, ‘authoriality’ is accessible conceptually only, in a manner analog-ous to the Foucauldian ‘author function’. Under such premises, as well, ‘authority’, ‘authorisation’ and ‘authorial intention’ become recognisable as exogenous to texts, not integral to them. Consequently, I propose to abandon ‘authority’, ‘authorisation’ and ‘authorial intention’ as overriding principles and arbiters in editorial scholarship. Scholarly editing instead should re-situate itself in relation to texts, to textual criticism, to literary criticism and to literary theory alike, and do so by re-focussing the method-ology of its own practice. It should relinquish the external props termed ‘authorised document’, ‘textual authority’, or ‘authorial intention’ hitherto deferred to. Instead, it should revitalise skills fundamental to inherited editorial scholarship, namely those of critically assessing, and of editorially realising, textual validity. To re-embed editorial scholarship in literary criticism and theory, moreover, the interpretative and hermeneutic dimensions of textual criticism and scholarly editing will need to be freshly mapped.

  1. Cloud Properties of CERES-MODIS Edition 4 and CERES-VIIRS Edition 1

    Science.gov (United States)

    Sun-Mack, Sunny; Minnis, Patrick; Chang, Fu-Lung; Hong, Gang; Arduini, Robert; Chen, Yan; Trepte, Qing; Yost, Chris; Smith, Rita; Brown, Ricky; hide

    2015-01-01

    The Clouds and Earth's Radiant Energy System (CERES) analyzes MODerate-resolution Imaging Spectroradiometer (MODIS) data and Visible Infrared Imaging Radiometer Suite (VIIRS) to derive cloud properties that are combine with aerosol and CERES broadband flux data to create a multi-parameter data set for climate study. CERES has produced over 15 years of data from Terra and over 13 years of data from Aqua using the CERES-MODIS Edition-2 cloud retrieval algorithm. A recently revised algorithm, CERESMODIS Edition 4, has been developed and is now generating enhanced cloud data for climate research (over 10 years for Terra and 8 years for Aqua). New multispectral retrievals of properties are included along with a multilayer cloud retrieval system. Cloud microphysical properties are reported at 3 wavelengths, 0.65, 1.24, and 2.1 microns to enable better estimates of the vertical profiles of cloud water contents. Cloud properties over snow are retrieved using the 1.24-micron channel. A new CERES-VIIRS cloud retrieval package was developed for the VIIRS spectral complement and is currently producing the CERES-VIIRS Edition 1 cloud dataset. The results from CERES-MODIS Edition 4 and CERES-VIIRS Edition 1 are presented and compared with each other and other datasets, including CALIPSO, CloudSat and the CERES-MODIS Edition-2 results.

  2. Nuclear reactor engineering: Reactor systems engineering. Fourth edition, Volume Two

    International Nuclear Information System (INIS)

    Glasstone, S.; Sesonske, A.

    1994-01-01

    This new edition of this classic reference combines broad yet in-depth coverage of nuclear engineering principles with practical descriptions of their application in the design and operation of nuclear power plants. Extensively updated, the fourth edition includes new materials on reactor safety and risk analysis, regulation, fuel management, waste management and operational aspects of nuclear power. This volume contains the following: the systems concept, design decisions, and information tools; energy transport; reactor fuel management and energy cost considerations; environmental effects of nuclear power and waste management; nuclear reactor safety and regulation; power reactor systems; plant operations; and advanced plants and the future

  3. Moderator materials for the Spallation Neutron Source

    International Nuclear Information System (INIS)

    Charlton, L.A.

    1999-01-01

    The Spallation Neutron Source (SNS) is a neutron source providing intense neutron fluxes that will be used for performing a large variety of neutron scattering experiments. SNS is to be completed and start operation in 2005. Protons will be accelerated to 1 GeV, stored in an accumulator ring, and then injected into a neutron-producing target. After leaving the target (Hg in the ca/se of SNS), the neutrons are prepared for experiments by first using a moderator to impose energy and width requirements on the neutron pulse. One of the most important ingredients is the moderator material. Four materials that are commonly used and that were considered for use in SNS are liquid hydrogen (L-H 2 ), liquid water (L-H 2 O), liquid methane (L-CH 4 ), and solid methane (S-CH 4 ). The spectra (neutron current versus neutron energy) for these four materials are shown. As may be seen, at low neutron energies ( 4 , which produces up to four times as many neutrons in this energy range as L-H 2 . The problem with the material is the internal storage of energy that can be spontaneously and explosively released. At energies of just above 10 MeV, the most effective moderator material is L-CH 4 . Polymerization problems, however, preclude its use at high powers (again such as in SNS), where the buildup of undesirable materials becomes prohibitive. This is, however, an important energy range for neutron experiments. Preliminary consideration is being given to a composite moderator that contains two adjacent sections, one of L-H 2 and one of L-H 2 O, which produces a spectrum that is very similar to L-CH 4

  4. Intense Pulsed Neutron Source: Progress report 1991--1996. 15. Anniversary edition -- Volume 2

    International Nuclear Information System (INIS)

    1996-01-01

    The 15th Anniversary Edition of the IPNS Progress Report is being published in recognition of the Intense Pulsed Neutron Source's first 15 years of successful operation as a user facility. To emphasize the importance of this milestone, the author shave made the design and organization of the report significantly different from previous IPNS Progress Reports. This report consists of two volumes. For Volume 1, authors were asked to prepare articles that highlighted recent scientific accomplishments at IPNS, from 1991 to present; to focus on and illustrate the scientific advances achieved through the unique capabilities of neutron studies performed by IPNS users; to report on specific activities or results from an instrument; or to focus on a body of work encompassing different neutron-scattering techniques. Articles were also included on the accelerator system, instrumentation, computing, target, and moderators. A list of published and ''in press' articles in journals, books, and conference proceedings, resulting from work done at IPNS since 1991, was compiled. This list is arranged alphabetically according to first author. Publication references in the articles are listed by last name of first author and year of publication. The IPNS experimental reports received since 1991 are compiled in Volume 2. Experimental reports referenced in the articles are listed by last name of first author, instrument designation, and experiment number

  5. Intense Pulsed Neutron Source: Progress report 1991--1996. 15. Anniversary edition -- Volume 1

    International Nuclear Information System (INIS)

    Marzec, B.

    1996-01-01

    The 15th Anniversary Edition of the IPNS Progress Report is being published in recognition of the Intense Pulsed Neutron Source's first 15 years of successful operation as a user facility. To emphasize the importance of this milestone, the authors have made the design and organization of the report significantly different from previous IPNS Progress Reports. This report consists of two volumes. For Volume 1, authors were asked to prepare articles that highlighted recent scientific accomplishments at IPNS, from 1991 to present; to focus on and illustrate the scientific advances achieved through the unique capabilities of neutron studies performed by IPNS users; to report on specific activities or results from an instrument; or to focus on a body of work encompassing different neutron-scattering techniques. Articles were also included on the accelerator system, instrumentation, computing, target, and moderators. A list of published and ''in press' articles in journals, books, and conference proceedings, resulting from work done at IPNS since 1991, was compiled. This list is arranged alphabetically according to first author. Publication references in the articles are listed by last name of first author and year of publication. The IPNS experimental reports received since 1991 are compiled in Volume 2. Experimental reports referenced in the articles are listed by last name of first author, instrument designation, and experiment number

  6. The principles of radio engineering and antennas. II Antennas (2nd revised and enlarged edition)

    Science.gov (United States)

    Belotserkovskii, G. B.

    This book represents the second part of a textbook for technical schools. The characteristics and parameters of antennas are considered along with transmission lines, the theory of single dipoles and radiator systems, and the technological realization of elements and units of the antenna-feeder system, taking into account filters and multiport networks for microwave communications applications, and ferrite circulators and isolators. The first edition of this textbook was published in 1969. For the current edition, the material in the first edition has been revised, and new material has been introduced. Much attention is given to microwave antennas, including, in particular, arrays with electrical scanning characteristics. Other topics discussed are related to the general principles of antennas, the matching of the impedance of transmission lines, the elements of transmission lines, aperture-type antennas for microwaves, and the functional characteristics of antennas for ultrashort waves.

  7. Fiber-reinforced composites materials, manufacturing, and design

    CERN Document Server

    Mallick, P K

    2007-01-01

    The newly expanded and revised edition of Fiber-Reinforced Composites: Materials, Manufacturing, and Design presents the most up-to-date resource available on state-of-the-art composite materials. This book is unique in that it not only offers a current analysis of mechanics and properties, but also examines the latest advances in test methods, applications, manufacturing processes, and design aspects involving composites. This third edition presents thorough coverage of newly developed materials including nanocomposites. It also adds more emphasis on underlying theories, practical methods, and problem-solving skills employed in real-world applications of composite materials. Each chapter contains new examples drawn from diverse applications and additional problems to reinforce the practical relevance of key concepts. New in The Third Edition: Contains new sections on material substitution, cost analysis, nano- and natural fibers, fiber architecture, and carbon-carbon composites Provides a new chapter on poly...

  8. Connectivity editing for quad-dominant meshes

    KAUST Repository

    Peng, Chihan

    2013-08-01

    We propose a connectivity editing framework for quad-dominant meshes. In our framework, the user can edit the mesh connectivity to control the location, type, and number of irregular vertices (with more or fewer than four neighbors) and irregular faces (non-quads). We provide a theoretical analysis of the problem, discuss what edits are possible and impossible, and describe how to implement an editing framework that realizes all possible editing operations. In the results, we show example edits and illustrate the advantages and disadvantages of different strategies for quad-dominant mesh design. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  9. Design of intense neutron source for fusion material study and the role of universities

    International Nuclear Information System (INIS)

    Ishino, Shiori

    1993-01-01

    Need and requirement for the intense neutron source for fusion materials study have been discussed for many years. Recently, international climate has been becoming gradually maturing to consider this problem more seriously because of the recognition of crucial importance of solving materials problems for fusion energy development. The present symposium was designed to discuss the problems associated with the intense neutron source for material irradiation studies which will have a potential for the National Institute for Fusion Science to become one of the important future research areas. The symposium comprises five sessions; first, the role of materials research in fusion development strategies was discussed followed by a brief summary of current IFMIF (International Fusion Materials Irradiation Facility) activity. Despite the pressing need for intense fusion neutron source, currently available neutron sources are reactor or accelerator based sources of which FFTF and LASREF were discussed. Then, various concepts of intense neutron source candidates were presented including ESNIT, which are currently under design by JAERI. In the fourth session, discussions were made on the study of materials with the intense neutron source from the viewpoint of materials scientists and engineers as the user of the facility. This is followed by discussions on the role of universities from the two stand points, namely, fusion irradiation studies and fusion materials development. Finally summary discussions were made by the participants, indicating important role fundamental studies in universities for the full utilization of irradiation data and the need of pure 14 MeV neutron source for fundamental studies together with the intense surrogate neutron sources. (author)

  10. [Preface for genome editing special issue].

    Science.gov (United States)

    Gu, Feng; Gao, Caixia

    2017-10-25

    Genome editing technology, as an innovative biotechnology, has been widely used for editing the genome from model organisms, animals, plants and microbes. CRISPR/Cas9-based genome editing technology shows its great value and potential in the dissection of functional genomics, improved breeding and genetic disease treatment. In the present special issue, the principle and application of genome editing techniques has been summarized. The advantages and disadvantages of the current genome editing technology and future prospects would also be highlighted.

  11. South Carolina Higher Education Statistical Abstract, 2014. 36th Edition

    Science.gov (United States)

    Armour, Mim, Ed.

    2014-01-01

    The South Carolina Higher Education Statistical Abstract is a comprehensive, single-source compilation of tables and graphs which report data frequently requested by the Governor, Legislators, college and university staff, other state government officials, and the general public. The 2014 edition of the Statistical Abstract marks the 36th year of…

  12. South Carolina Higher Education Statistical Abstract, 2015. 37th Edition

    Science.gov (United States)

    Armour, Mim, Ed.

    2015-01-01

    The South Carolina Higher Education Statistical Abstract is a comprehensive, single-source compilation of tables and graphs which report data frequently requested by the Governor, Legislators, college and university staff, other state government officials, and the general public. The 2015 edition of the Statistical Abstract marks the 37th year of…

  13. Import/Export Service of Radioactive Material and Radioactive Sources Service

    CERN Multimedia

    2004-01-01

    Please note that the Import/Export Service of radioactive material (http://cern.ch/service-rp-shipping/ - e-mail : service-rp-shipping@cern.ch) and the Radioactive Sources Service (http://cern.ch/service-radioactive-sources - e-mail : service-radioactive-sources@cern.ch) at bldg. 24/E-024 will be closed on FRIDAY 10 SEPTEMBER 2004. Tel. 73171

  14. Risk Prevention for Nuclear Materials and Radioactive Sources

    International Nuclear Information System (INIS)

    Badawy, I.

    2008-01-01

    The present paper investigates the parameters which may have effects on the safety of nuclear materials and other radioactive sources used in peaceful applications of atomic energy. The emergency response planning in such situations are also indicated. In synergy with nuclear safety measures, an approach is developed in this study for risk prevention. It takes into consideration the collective implementation of measures of nuclear material accounting and control, physical protection and monitoring of such strategic and dangerous materials in an integrated and coordinated real-time mode at a nuclear or radiation facility and in any time

  15. New shielding material development for compact accelerator-driven neutron source

    Directory of Open Access Journals (Sweden)

    Guang Hu

    2017-04-01

    Full Text Available The Compact Accelerator-driven Neutron Source (CANS, especially the transportable neutron source is longing for high effectiveness shielding material. For this reason, new shielding material is researched in this investigation. The component of shielding material is designed and many samples are manufactured. Then the attenuation detection experiments were carried out. In the detections, the dead time of the detector appeases when the proton beam is too strong. To grasp the linear range and nonlinear range of the detector, two currents of proton are employed in Pb attenuation detections. The transmission ratio of new shielding material, polyethylene (PE, PE + Pb, BPE + Pb is detected under suitable current of proton. Since the results of experimental neutrons and γ-rays appear as together, the MCNP and PHITS simulations are applied to assisting the analysis. The new shielding material could reduce of the weight and volume compared with BPE + Pb and PE + Pb.

  16. Statistical Physics Approaches to RNA Editing

    Science.gov (United States)

    Bundschuh, Ralf

    2012-02-01

    The central dogma of molecular Biology states that DNA is transcribed base by base into RNA which is in turn translated into proteins. However, some organisms edit their RNA before translation by inserting, deleting, or substituting individual or short stretches of bases. In many instances the mechanisms by which an organism recognizes the positions at which to edit or by which it performs the actual editing are unknown. One model system that stands out by its very high rate of on average one out of 25 bases being edited are the Myxomycetes, a class of slime molds. In this talk we will show how the computational methods and concepts from statistical Physics can be used to analyze DNA and protein sequence data to predict editing sites in these slime molds and to guide experiments that identified previously unknown types of editing as well as the complete set of editing events in the slime mold Physarum polycephalum.

  17. The Gift Network: Dave Eggers and the Circulation of Second Editions

    Directory of Open Access Journals (Sweden)

    Jacqueline O’Dell

    2017-07-01

    Full Text Available This article argues for a view of the gift as an affective network and investigates how Dave Eggers’s practice of publishing second editions works to produce this network. Framing my discussion of the gift with Sara Ahmed’s work on affective economies, I suggest that the gift, like affect, is best understood as a surplus effect of circulation. I argue that Eggers negotiates the gift’s double bind by emphasizing the impossibility of identifying a “pure” gift or an authoritative “original” edition; his double editions show how the gift survives through the surplus values generated by their ongoing circulation. Eggers's symbolic and material gift network ultimately depends on the uncertainty and mystification emblematic of Eggers’s anxious aesthetic and mode of recirculation, adding to critical conversations that position Eggers’s aesthetic within movements of new sincerity or post-irony.

  18. Differences in fMRI intersubject correlation while viewing unedited and edited videos of dance performance.

    Science.gov (United States)

    Herbec, Aleksandra; Kauppi, Jukka-Pekka; Jola, Corinne; Tohka, Jussi; Pollick, Frank E

    2015-10-01

    Intersubject correlation (ISC) analysis of functional magnetic resonance imaging (fMRI) data provides insight into how continuous streams of sensory stimulation are processed by groups of observers. Although edited movies are frequently used as stimuli in ISC studies, there has been little direct examination of the effect of edits on the resulting ISC maps. In this study we showed 16 observers two audiovisual movie versions of the same dance. In one experimental condition there was a continuous view from a single camera (Unedited condition) and in the other condition there were views from different cameras (Edited condition) that provided close up views of the feet or face and upper body. We computed ISC maps for each condition, as well as created a map that showed the difference between the conditions. The results from the Unedited and Edited maps largely overlapped in the occipital and temporal cortices, although more voxels were found for the Edited map. The difference map revealed greater ISC for the Edited condition in the Postcentral Gyrus, Lingual Gyrus, Precentral Gyrus and Medial Frontal Gyrus, while the Unedited condition showed greater ISC in only the Superior Temporal Gyrus. These findings suggest that the visual changes associated with editing provide a source of correlation in maps obtained from edited film, and highlight the utility of using maps to evaluate the difference in ISC between conditions. Copyright © 2015. Published by Elsevier Ltd.

  19. Human Genome Editing and Ethical Considerations.

    Science.gov (United States)

    Krishan, Kewal; Kanchan, Tanuj; Singh, Bahadur

    2016-04-01

    Editing human germline genes may act as boon in some genetic and other disorders. Recent editing of the genome of the human embryo with the CRISPR/Cas9 editing tool generated a debate amongst top scientists of the world for the ethical considerations regarding its effect on the future generations. It needs to be seen as to what transformation human gene editing brings to humankind in the times to come.

  20. Security of Radioactive Sources. Implementing Guide (French Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    There are concerns that terrorist or criminal groups could gain access to high activity radioactive sources and use these sources maliciously. The IAEA is working with Member States to increase control, accounting and security of radioactive sources to prevent their malicious use and the associated potential consequences. Based on extensive input from technical and legal experts, this implementation guide sets forth guidance on the security of sources and will serve as a useful tool for legislators and regulators, physical protection specialists and facility and transport operators, as well as for law enforcement officers.

  1. Cluster editing

    DEFF Research Database (Denmark)

    Böcker, S.; Baumbach, Jan

    2013-01-01

    . The problem has been the inspiration for numerous algorithms in bioinformatics, aiming at clustering entities such as genes, proteins, phenotypes, or patients. In this paper, we review exact and heuristic methods that have been proposed for the Cluster Editing problem, and also applications......The Cluster Editing problem asks to transform a graph into a disjoint union of cliques using a minimum number of edge modifications. Although the problem has been proven NP-complete several times, it has nevertheless attracted much research both from the theoretical and the applied side...

  2. LdShake: Learning Design Solutions Sharing and Co-Edition

    Science.gov (United States)

    Hernandez-Leo, Davinia; Romeo, Lauren; Carralero, Miguel A.; Chacon, Jonathan; Carrio, Mar; Moreno, Pau; Blat, Josep

    2011-01-01

    Two important challenges that teachers are currently facing are the sharing and the collaborative authoring of their learning design solutions, such as didactical units and learning materials. On the one hand, there are tools that can be used for the creation of design solutions and only some of them facilitate the co-edition. However, they do not…

  3. Determination of internationally controlled materials according to provisions of the law for the regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1977-01-01

    According to the provisions of The Law, those stipulated as internationally controlled materials are nuclear source materials, nuclear fuel materials, moderating materials, reactors and facilities, transferred from such as the U.S.A., the U.K. and Canada on the agreements of peaceful uses of atomic energy, and nuclear fuel materials accruing therefrom. (Mori, K.)

  4. Strong neutron sources - How to cope with weapon material production capabilities of fusion and spallation neutron sources?

    International Nuclear Information System (INIS)

    Englert, M.; Franceschini, G.; Liebert, W.

    2013-01-01

    In this article we investigate the potential and relevance for weapon material production in future fusion power plants and spallation neutron sources (SNS) and sketch what should be done to strengthen these technologies against a non-peaceful use. It is shown that future commercial fusion reactors may have military implications: first, they provide an easy source of tritium for weapons, an element that does not fall under safeguards and for which diversion from a plant could probably not be detected even if some tritium accountancy is implemented. Secondly, large fusion reactors - even if not designed for fissile material breeding - could easily produce several hundred kg Pu per year with high weapon quality and very low source material requirements. If fusion-only reactors will prevail over fission-fusion hybrids in the commercialization phase of fusion technology, the safeguard challenge will be more of a legal than of a technical nature. In pure fusion reactors (and in most SNS) there should be no nuclear material present at any time by design. The presence of undeclared nuclear material would indicate a military use of the plant. This fact offers a clear-cut detection criterion for a covert use of a declared facility. Another important point is that tritium does not fall under the definition of 'nuclear material', so a pure fusion reactor or a SNS that do not use nuclear materials are not directly falling under any international non-proliferation treaty requirements. Non-proliferation treaties have to be amended to take into account that fact. (A.C.)

  5. Decimal Classification Editions

    OpenAIRE

    Zenovia Niculescu

    2009-01-01

    The study approaches the evolution of Dewey Decimal Classification editions from the perspective of updating the terminology, reallocating and expanding the main and auxilary structure of Dewey indexing language. The comparative analysis of DDC editions emphasizes the efficiency of Dewey scheme from the point of view of improving the informational offer, through basic index terms, revised and developed, as well as valuing the auxilary notations.

  6. Accelerator-based intense neutron source for materials R ampersand D

    International Nuclear Information System (INIS)

    Jameson, R.A.

    1990-01-01

    Accelerator-based neutron sources for R ampersand D of materials in nuclear energy systems, including fusion reactors, can provide sufficient neutron flux, flux-volume, fluence and other attractive features for many aspects of materials research. The neutron spectrum produced from the D-Li reaction has been judged useful for many basic materials research problems, and to be a satisfactory approximation to that of the fusion process. The technology of high-intensity linear accelerators can readily be applied to provide the deuteron beam for the neutron source. Earlier applications included the Los Alamos Meson Physics Facility and the Fusion Materials Irradiation Test facility prototype. The key features of today's advanced accelerator technology are presented to illustrate the present state-of-the-art in terms of improved understanding of basic physical principles and engineering technique, and to show how these advances can be applied to present demands in a timely manner. These features include how to produce an intense beam current with the high quality required to minimize beam losses along the accelerator and transport system that could cause maintenance difficulties, by controlling the beam emittance through proper choice of the operating frequency, balancing of the forces acting on the beam, and realization in practical hardware. A most interesting aspect for materials researchers is the increased flexibility and opportunities for experimental configurations that a modern accelerator-based source could add to the set of available tools. 8 refs., 5 figs

  7. The genome editing revolution

    DEFF Research Database (Denmark)

    Stella, Stefano; Montoya, Guillermo

    2016-01-01

    -Cas system has become the main tool for genome editing in many laboratories. Currently the targeted genome editing technology has been used in many fields and may be a possible approach for human gene therapy. Furthermore, it can also be used to modifying the genomes of model organisms for studying human......In the last 10 years, we have witnessed a blooming of targeted genome editing systems and applications. The area was revolutionized by the discovery and characterization of the transcription activator-like effector proteins, which are easier to engineer to target new DNA sequences than...... sequence). This ribonucleoprotein complex protects bacteria from invading DNAs, and it was adapted to be used in genome editing. The CRISPR ribonucleic acid (RNA) molecule guides to the specific DNA site the Cas9 nuclease to cleave the DNA target. Two years and more than 1000 publications later, the CRISPR...

  8. Guidelines for health technology assessment in Thailand (second edition)--the development process.

    Science.gov (United States)

    Chaikledkaew, Usa; Kittrongsiri, Kankamon

    2014-05-01

    The first Thai-specific HTA guidelines were completed in 2008 with the aim of ensuring that all HTA data was accurate, of high quality, and relevant for making decisions pertaining to healthcare resource allocation. Based on a quality assessment of 89 economic evaluation studies in the Thai context published in international academic journals between 1982 and 2012, the analysis revealed a significant increase in quality of data sources and result reporting in studies published after the dissemination of the first Thai HTA guidelines. As the first Thai HTA guidelines were developed in 2008, a number of areas for improvement have been identified. Therefore, the objective of this chapter is to describe the development process of this second edition of HTA guidelines for Thailand which builds on the success of the first edition, while attempting to address some of the identified limitations of the first edition and reflect the changes that the health care and policy contexts have undergone in the intervening years. It is hoped that this second edition will continue to build on these successes so that policy decision making becomes increasingly evidence-based.

  9. Human Germline Genome Editing.

    Science.gov (United States)

    Ormond, Kelly E; Mortlock, Douglas P; Scholes, Derek T; Bombard, Yvonne; Brody, Lawrence C; Faucett, W Andrew; Garrison, Nanibaa' A; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E

    2017-08-03

    With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Genetic Counselors. These groups, as well as the American Society for Reproductive Medicine, Asia Pacific Society of Human Genetics, British Society for Genetic Medicine, Human Genetics Society of Australasia, Professional Society of Genetic Counselors in Asia, and Southern African Society for Human Genetics, endorsed the final statement. The statement includes the following positions. (1) At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human pregnancy. (2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing. There should be no prohibition on making public funds available to support this research. (3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input. Copyright © 2017 American Society of Human Genetics. All rights reserved.

  10. Composite materials for aircraft structures

    National Research Council Canada - National Science Library

    Baker, A. A; Dutton, Stuart; Kelly, Donald

    2004-01-01

    ... materials for aircraft structures / Alan Baker, Stuart Dutton, and Donald Kelly- 2nd ed. p. cm. - (Education series) Rev. ed. of: Composite materials for aircraft structures / edited by B. C. Hos...

  11. Precision genome editing

    DEFF Research Database (Denmark)

    Steentoft, Catharina; Bennett, Eric P; Schjoldager, Katrine Ter-Borch Gram

    2014-01-01

    Precise and stable gene editing in mammalian cell lines has until recently been hampered by the lack of efficient targeting methods. While different gene silencing strategies have had tremendous impact on many biological fields, they have generally not been applied with wide success in the field...... of glycobiology, primarily due to their low efficiencies, with resultant failure to impose substantial phenotypic consequences upon the final glycosylation products. Here, we review novel nuclease-based precision genome editing techniques enabling efficient and stable gene editing, including gene disruption...... by introducing single or double-stranded breaks at a defined genomic sequence. We here compare and contrast the different techniques and summarize their current applications, highlighting cases from the field of glycobiology as well as pointing to future opportunities. The emerging potential of precision gene...

  12. Time-resolved materials science opportunities using synchrotron x-ray sources

    International Nuclear Information System (INIS)

    Larson, B.C.; Tischler, J.Z.

    1995-06-01

    The high brightness, high intensity, and pulsed time-structure of synchrotron sources provide new opportunities for time-resolved x-ray diffraction investigations. With third generation synchrotron sources coming on line, high brilliance and high brightness are now available in x-ray beams with the highest flux. In addition to the high average flux, the instantaneous flux available in synchrotron beams is greatly enhanced by the pulsed time structure, which consists of short bursts of x-rays that are separated by ∼tens to hundreds of nanoseconds. Time-resolved one- and two-dimensional position sensitive detection techniques that take advantage of synchrotron radiation for materials science x-ray diffraction investigations are presented, and time resolved materials science applications are discussed in terms of recent diffraction and spectroscopy results and materials research opportunities

  13. Methodology for safety and security of radioactive sources and materials. The Israeli approach

    International Nuclear Information System (INIS)

    Keren, M.

    1998-01-01

    About 10 Radioactive incidents occurred in Israel during 1996-1997. Some of them were theft or lost of Radioactive equipment or sources, some happened because misuse of Radioactive equipment and some of other reasons. Part of them could be eliminated if a better methodological attitude to the subject existed. A new methodology for notification, registration and licensing is described. Hopefully this methodology will increase defense in depth and the Safety and Security of Radioactive sources and materials. Information on the inventory of Radioactive sources and materials is essential. Where they are situated, what is the supply rate or all history from berth to grave. Persons involved are important: Who are the Radiation Safety Officers (RSO), what is their training and updating programs. As much as possible information on the site and places where those Radioactive sources and materials are used. Procedures for security of sources and materials is part of site information, beside safety precautions. Users are obliged to inform on any changes and to ask for confirmation to those changes. The same is when high activity sources are moved across the country. (author)

  14. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-12

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  15. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan; Zhang, Eugene; Kobayashi, Yoshihiro; Wonka, Peter

    2011-01-01

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  16. [Genome editing of industrial microorganism].

    Science.gov (United States)

    Zhu, Linjiang; Li, Qi

    2015-03-01

    Genome editing is defined as highly-effective and precise modification of cellular genome in a large scale. In recent years, such genome-editing methods have been rapidly developed in the field of industrial strain improvement. The quickly-updating methods thoroughly change the old mode of inefficient genetic modification, which is "one modification, one selection marker, and one target site". Highly-effective modification mode in genome editing have been developed including simultaneous modification of multiplex genes, highly-effective insertion, replacement, and deletion of target genes in the genome scale, cut-paste of a large DNA fragment. These new tools for microbial genome editing will certainly be applied widely, and increase the efficiency of industrial strain improvement, and promote the revolution of traditional fermentation industry and rapid development of novel industrial biotechnology like production of biofuel and biomaterial. The technological principle of these genome-editing methods and their applications were summarized in this review, which can benefit engineering and construction of industrial microorganism.

  17. Materials irradiation subpanel report to BESAC neutron sources and research panel

    International Nuclear Information System (INIS)

    Birtcher, R.C.; Goland, A.N.; Lott, R.

    1992-01-01

    The future success of the nuclear power option in the US (fission and fusion) depends critically on the continued existence of a healthy national materials-irradiation program. Consideration of the requirements for acceptable materials-irradiation systems in a new neutron source has led the subcommittee to identify an advanced steady-state reactor (ANS) as a better choice than a spallation neutron source. However, the subcommittee also hastens to point out that the ANS cannot stand alone as the nation's sole high-flux mixed-spectrum neutron irradiation source in the next century. It must be incorporated in a broader program that includes other currently existing neutron irradiation facilities. Upgrading and continuing support for these facilities must be planned. In particular, serious consideration should be given to converting the HFIR into a dedicated materials test reactor, and long-term support for several university reactors should be established

  18. Deletions in cox2 mRNA result in loss of splicing and RNA editing and gain of novel RNA editing sites.

    Directory of Open Access Journals (Sweden)

    Stefanie Grüttner

    Full Text Available As previously demonstrated, the maize cox2 RNA is fully edited in cauliflower mitochondria. Use of constructs with a deleted cox2 intron, however, led to a loss of RNA editing at almost all editing sites, with only a few sites still partially edited. Likewise, one deletion in exon 1 and three in exon 2 abolish RNA editing at all cox2 sites analyzed. Furthermore, intron splicing is abolished using these deletions. Mutation of a cytosine residue, which is normally edited and localized directly adjacent to the intron, to thymidine did not result in restoration of splicing, indicating that the loss of splicing was not due to loss of RNA editing. One deletion in exon 2 did not lead to loss of splicing. Instead, most editing sites were found to be edited, only three were not edited. Unexpectedly, we observed additional RNA editing events at new sites. Thus it appears that deletions in the cox2 RNA sequence can have a strong effect on RNA processing, leading to loss of splicing, loss of editing at all sites, or even to a gain of new editing sites. As these effects are not limited to the vicinity of the respective deletions, but appear to be widespread or even affect all editing sites, they may not be explained by the loss of PPR binding sites. Instead, it appears that several parts of the cox2 transcript are required for proper RNA processing. This indicates the roles of the RNA sequence and structural elements in the recognition of the editing sites.

  19. Decimal Classification Editions

    Directory of Open Access Journals (Sweden)

    Zenovia Niculescu

    2009-01-01

    Full Text Available The study approaches the evolution of Dewey Decimal Classification editions from the perspective of updating the terminology, reallocating and expanding the main and auxilary structure of Dewey indexing language. The comparative analysis of DDC editions emphasizes the efficiency of Dewey scheme from the point of view of improving the informational offer, through basic index terms, revised and developed, as well as valuing the auxilary notations.

  20. RNA Editing and Drug Discovery for Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Wei-Hsuan Huang

    2013-01-01

    Full Text Available RNA editing is vital to provide the RNA and protein complexity to regulate the gene expression. Correct RNA editing maintains the cell function and organism development. Imbalance of the RNA editing machinery may lead to diseases and cancers. Recently, RNA editing has been recognized as a target for drug discovery although few studies targeting RNA editing for disease and cancer therapy were reported in the field of natural products. Therefore, RNA editing may be a potential target for therapeutic natural products. In this review, we provide a literature overview of the biological functions of RNA editing on gene expression, diseases, cancers, and drugs. The bioinformatics resources of RNA editing were also summarized.

  1. The fractal nature materials microstructure influence on electrochemical energy sources

    Directory of Open Access Journals (Sweden)

    Mitić V.V.

    2015-01-01

    Full Text Available With increasing of the world energy crisis, research for new, renewable and alternative energy sources are in growth. The focus is on research areas, sometimes of minor importance and applications, where the different synthesis methods and microstructure properties optimization, performed significant improvement of output materials’ and components’ electro-physical properties, which is important for higher energy efficiency and in the electricity production (batteries and battery systems, fuel cells and hydrogen energy contribution. Also, the storage tanks capacity improvement, for the energy produced on such way, which is one of the most important development issues in the energy sphere, represents a very promising research and application area. Having in mind, the results achieved in the electrochemical energy sources field, especially electrolyte development, these energy sources, materials fractal nature optimization analysis contribution, have been investigated. Based on materials fractal structure research field, particularly electronic materials, we have performed microstructure influence parameters research in electrochemistry area. We have investigated the Ho2O3 concentration influence (from 0.01wt% to 1wt% and sintering temperature (from 1320°C to 1380°C, as consolidation parameters, and thus, also open the electrochemical function fractalization door and in the basic thermodynamic parameters the fractal correction introduced. The fractal dimension dependence on additive concentration is also investigated. [Projekat Ministarstva nauke Republike Srbije, br. 172057: Directed synthesis, structure and properties of multifunctional materials

  2. Strategies of Qualitative Inquiry. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna S., Ed.

    2007-01-01

    "Strategies of Qualitative Inquiry, Third Edition," the second volume in the paperback version of "The SAGE Handbook of Qualitative Research, 3rd Edition," consists of Part III of the handbook ("Strategies of Inquiry"). "Strategies of Qualitative Inquiry, Third Edition" presents the major tactics--historically, the research methods--that…

  3. 2011 Radioactive Materials Usage Survey for Unmonitored Point Sources

    Energy Technology Data Exchange (ETDEWEB)

    Sturgeon, Richard W. [Los Alamos National Laboratory

    2012-06-27

    This report provides the results of the 2011 Radioactive Materials Usage Survey for Unmonitored Point Sources (RMUS), which was updated by the Environmental Protection (ENV) Division's Environmental Stewardship (ES) at Los Alamos National Laboratory (LANL). ES classifies LANL emission sources into one of four Tiers, based on the potential effective dose equivalent (PEDE) calculated for each point source. Detailed descriptions of these tiers are provided in Section 3. The usage survey is conducted annually; in odd-numbered years the survey addresses all monitored and unmonitored point sources and in even-numbered years it addresses all Tier III and various selected other sources. This graded approach was designed to ensure that the appropriate emphasis is placed on point sources that have higher potential emissions to the environment. For calendar year (CY) 2011, ES has divided the usage survey into two distinct reports, one covering the monitored point sources (to be completed later this year) and this report covering all unmonitored point sources. This usage survey includes the following release points: (1) all unmonitored sources identified in the 2010 usage survey, (2) any new release points identified through the new project review (NPR) process, and (3) other release points as designated by the Rad-NESHAP Team Leader. Data for all unmonitored point sources at LANL is stored in the survey files at ES. LANL uses this survey data to help demonstrate compliance with Clean Air Act radioactive air emissions regulations (40 CFR 61, Subpart H). The remainder of this introduction provides a brief description of the information contained in each section. Section 2 of this report describes the methods that were employed for gathering usage survey data and for calculating usage, emissions, and dose for these point sources. It also references the appropriate ES procedures for further information. Section 3 describes the RMUS and explains how the survey results are

  4. Nuclear Material Detection by One-Short-Pulse-Laser-Driven Neutron Source

    International Nuclear Information System (INIS)

    Favalli, Andrea; Aymond, F.; Bridgewater, Jon S.; Croft, Stephen; Deppert, O.; Devlin, Matthew James; Falk, Katerina; Fernandez, Juan Carlos; Gautier, Donald Cort; Gonzales, Manuel A.; Goodsell, Alison Victoria; Guler, Nevzat; Hamilton, Christopher Eric; Hegelich, Bjorn Manuel; Henzlova, Daniela; Ianakiev, Kiril Dimitrov; Iliev, Metodi; Johnson, Randall Philip; Jung, Daniel; Kleinschmidt, Annika; Koehler, Katrina Elizabeth; Pomerantz, Ishay; Roth, Markus; Santi, Peter Angelo; Shimada, Tsutomu; Swinhoe, Martyn Thomas; Taddeucci, Terry Nicholas; Wurden, Glen Anthony; Palaniyappan, Sasikumar; McCary, E.

    2015-01-01

    Covered in the PowerPoint presentation are the following areas: Motivation and requirements for active interrogation of nuclear material; laser-driven neutron source; neutron diagnostics; active interrogation of nuclear material; and, conclusions, remarks, and future works.

  5. Safe transport of radioactive material. Second edition

    International Nuclear Information System (INIS)

    1991-01-01

    The transport of radioactive material embraces the carriage of radioisotopes for industrial, medical and research uses, and the movement of waste, in addition to consignments of nuclear fuel cycle material. It has been estimated that between eighteen and thirty-eight million package shipments take place each year. On the recommendation of the Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM), which enjoys wide representations from the Agency's Member States and international organizations, the Secretariat is preparing a training kit comprising this training manual and complementary visual aids. The kit is intended to be the basis for an extensive course on the subject and can be used in whole or in part for inter-regional, regional and even national training purposes. Member States can thus benefit from the material either through training courses sponsored by the Agency, or, alternatively, organized by themselves. As a step towards achieving that goal, the current training manual was compiled using material from the first Inter-Regional Training Course on the Safe Transport of Radioactive material that was held in co-operation with the Nuclear Power Training Centre of the then Central Electricity Generating Board at Bristol, United Kingdom. This Manual was initially published in 1990. On the recommendation of the Agency's Standing Advisory Group on the Safe Transport of Radioactive Material (SAGSTRAM), the Manual has since been expanded and updated in time for the second Inter-Regional Training Course, that will in 1991 similarly be held in Bristol. Refs, figs, tabs

  6. Dictionary of minor planet names addendum to 6th edition 2012-2014

    CERN Document Server

    Schmadel, Lutz D

    2015-01-01

    The quantity of numbered minor planets is now approaching half a million. Together with this Addendum, the sixth edition of the Dictionary of Minor Planet Names, which is the IAU's official reference for the field, now covers more than 19,000 named minor planets. In addition to being of practical value for identification purposes, the Dictionary of Minor Planet Names provides authoritative information about the basis for the rich and colorful variety of ingenious names, from heavenly goddesses to artists, from scientists to Nobel laureates, from historical or political figures to ordinary women and men, from mountains to buildings, as well as a variety of compound terms and curiosities. This Addendum to the 6th edition of the Dictionary of Minor Planet Names adds approximately 2200 entries. It also contains many corrections, revisions and updates to the entries published in earlier editions. This work is an abundant source of information for anyone interested in minor planets and who enjoys reading about the ...

  7. Beam plasma 14 MeV neutron source for fusion materials development

    International Nuclear Information System (INIS)

    Ravenscroft, D.; Bulmer, D.; Coensgen, F.; Doggett, J.; Molvik, A.; Souza, P.; Summers, L.; Williamson, V.

    1991-09-01

    The conceptual engineering design and expected performance for a 14 MeV DT neutron source is detailed. The source would provide an intense neutron flux for accelerated testing of fusion reactor materials. The 150-keV neutral beams inject energetic deuterium atoms, that ionize, are trapped, then react with a warm (200 eV), dense tritium target plasma. This produces a neutron source strength of 3.6 x 10 17 n/sec for a neutron power density at the plasma edge of 5--10 MW/m 2 . This is several times the ∼2 MW/m 2 anticipated at the first wall of fusion reactors. This high flux provides accelerated end-of-life tests of 1- to 2-year duration, thus making materials development possible. The modular design of the source and the facilities are described

  8. Country Nuclear Power Profiles. 2016 Edition

    International Nuclear Information System (INIS)

    2016-12-01

    The Country Nuclear Power Profiles compile background information on the status and development of nuclear power programmes in Member States. The publication summarizes organizational and industrial aspects of nuclear power programmes and provides information about the relevant legislative, regulatory and international framework in each State. Its descriptive and statistical overview of the overall economic, energy and electricity situation in each State and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programmes throughout the world. This 2016 edition, issued on CD-ROM, contains updated country information for 51 States.

  9. Country Nuclear Power Profiles - 2015 Edition

    International Nuclear Information System (INIS)

    2015-08-01

    The Country Nuclear Power Profiles compile background information on the status and development of nuclear power programmes in Member States. The publication summarizes organizational and industrial aspects of nuclear power programmes and provides information about the relevant legislative, regulatory and international framework in each State. Its descriptive and statistical overview of the overall economic, energy and electricity situation in each State and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programmes throughout the world. This 2015 edition, issued on CD-ROM, contains updated country information for 51 States

  10. Country Nuclear Power Profiles - 2013 Edition

    International Nuclear Information System (INIS)

    2013-08-01

    The Country Nuclear Power Profiles compile background information on the status and development of nuclear power programmes in Member States. The CNPP summarizes organizational and industrial aspects of nuclear power programs and provides information about the relevant legislative, regulatory, and international framework in each country. Its descriptive and statistical overview of the overall economic, energy, and electricity situation in each country and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programs in the world. This 2013 edition, issued on CD-ROM and Web pages, contains updated country information for 51 countries

  11. Mass conservation for instantaneous sources in FEM3 simulations of material dispersion

    International Nuclear Information System (INIS)

    Rodean, H.C.

    1987-11-01

    This report presents the results of a systematic study in which it is shown that the numerical integration errors in determining material mass content are negligible; the material phase-change model by itself is not a cause of material mass variation; and a linear relation between fractional mass change and fractional density change at the source center for given mesh and source geometries exists over a range of values from 10 -5 to 10 -1 . This suggests that the omission of the ∂ rho/∂t term from the mass conservation equation is the cause of the observed non-conservation of mass by FEM3. It is shown that these mass variations can be minimized by minimizing the initial density gradients in the source region. 5 refs., 18 figs., 4 tabs

  12. The Critical Editing of a Musical Work on the Basis of Incomplete Performance Material: Scheibe’s Second Passion Cantata, ‘Sørge-Cantate ved Christi Grav’ (1769)

    DEFF Research Database (Denmark)

    Hauge, Peter

    2016-01-01

    When dealing with the critical editing of music of the ighteenth century, it seems fairly easy to select the composer’s ink fair manuscript as copy text – that is, if such a manuscript has survived. In a few cases, however, also the original performance material is available. The article argues t...... of intricate problems since it contains contradictory information on performance practice, and the editor has therefore to make some diffi cult choices....

  13. Surface, interface and bulk materials characterization using Indus synchrotron sources

    International Nuclear Information System (INIS)

    Phase, Deodatta M.

    2014-01-01

    Synchrotron radiation sources, providing intense, polarized and stable beams of ultra violet, soft and hard x-ray photons, are having great impact on physics, chemistry, biology, materials science and other areas research. In particular synchrotron radiation has revolutionized materials characterization techniques by enhancing its capabilities for investigating the structural, electronic and magnetic properties of solids. The availability of synchrotron sources and necessary instrumentation has led to considerable improvements in spectral resolution and intensities. As a result, application scope of different materials characterization techniques has tremendously increased particularly in the analysis of solid surfaces, interfaces and bulk materials. The Indian synchrotron storage ring, Indus-1 and Indus-2 are in operation at RRCAT, Indore. The UGC-DAE CSR with the help of university scientist had designed and developed an angle integrated photoelectron spectroscopy (AlPES) beam line on Indus-1 storage ring of 450 MeV and polarized light beam line for soft x-ray absorption spectroscopy (SXAS) on Indus-2 storage ring of 2.5 GeV. (author)

  14. Tokamaks (Second Edition)

    Energy Technology Data Exchange (ETDEWEB)

    Stott, Peter [JET, UK (United Kingdom)

    1998-10-01

    The first edition of John Wesson's book on tokamaks, published in 1987, established itself as essential reading for researchers in the field of magnetic confinement fusion: it was an excellent introduction for students to tokamak physics and also a valuable reference work for the more experienced. The second edition, published in 1997, has been completely rewritten and substantially enlarged (680 pages compared with 300). The new edition maintains the aim of providing a simple introduction to basic tokamak physics, but also includes discussion of the substantial advances in fusion research during the past decade. The new book, like its predecessor, is well written and commendable for its clarity and accuracy. In fact many of the chapters are written by a series of co-authors bringing the benefits of a wide range of expertise but, by careful editing, Wesson has maintained a uniformity of style and presentation. The chapter headings and coverage for the most part remain the same - but are expanded considerably and brought up to date. The most substantial change is that the single concluding chapter in the first edition on 'Experiments' has been replaced by three chapters: 'Tokamak experiments' which deals with some of the earlier key experiments plus a selection of recent small and medium-sized devices, 'Large experiments' which gives an excellent summary of the main results from the four large tokamaks - TFTR, JET, JT60/JT60U and DIII-D, and 'The future' which gives a very short (possibly too short in my opinion) account of reactors and ITER. This is an excellent book, which I strongly recommend should have a place - on the desk rather than in the bookshelf - of researchers in magnetic confinement fusion. (book review)

  15. Tokamaks (Second Edition)

    International Nuclear Information System (INIS)

    Stott, Peter

    1998-01-01

    The first edition of John Wesson's book on tokamaks, published in 1987, established itself as essential reading for researchers in the field of magnetic confinement fusion: it was an excellent introduction for students to tokamak physics and also a valuable reference work for the more experienced. The second edition, published in 1997, has been completely rewritten and substantially enlarged (680 pages compared with 300). The new edition maintains the aim of providing a simple introduction to basic tokamak physics, but also includes discussion of the substantial advances in fusion research during the past decade. The new book, like its predecessor, is well written and commendable for its clarity and accuracy. In fact many of the chapters are written by a series of co-authors bringing the benefits of a wide range of expertise but, by careful editing, Wesson has maintained a uniformity of style and presentation. The chapter headings and coverage for the most part remain the same - but are expanded considerably and brought up to date. The most substantial change is that the single concluding chapter in the first edition on 'Experiments' has been replaced by three chapters: 'Tokamak experiments' which deals with some of the earlier key experiments plus a selection of recent small and medium-sized devices, 'Large experiments' which gives an excellent summary of the main results from the four large tokamaks - TFTR, JET, JT60/JT60U and DIII-D, and 'The future' which gives a very short (possibly too short in my opinion) account of reactors and ITER. This is an excellent book, which I strongly recommend should have a place - on the desk rather than in the bookshelf - of researchers in magnetic confinement fusion. (book review)

  16. Safety of radiation sources and security of radioactive materials. Contributed papers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    The International Atomic Energy Agency (IAEA) in co-operation with the European Commission (EC), International Criminal Police Organization (INTERPOL) and the World Customs Organization (WCO) organized an International Conference on the Safety of Radiation Sources and the Security of Radioactive Materials, in Dijon, France, from 14 to 18 September 1998. The Government of France hosted this Conference through the Commissariat a l`energie atomique, Direction des applications militaires (CEA/DAM). This TECDOC contains the contributed papers dealing with the topics of this Conference which were accepted by the Conference Programme Committee for presentation. The papers written in one of the two working languages of the Conference, English or French are presented here each by a separate abstract. Ten technical sessions covered the following subjects: the regulatory control of radiation sources, including systems for notification, authorization and inspection; safety assessment techniques applied to radiation sources and design and technological measures including defense in depth and good engineering practice; managerial measures, including safety culture, human factors, quality assurance, qualified experts, training and education; learning from operational experience; international co-operation, including reporting systems and databases; verification of compliance, monitoring of compliance and assessment of the effectiveness of national programmes for the safety of sources; measures to prevent breaches in the security of radioactive materials, experience with criminal acts involving radioactive materials; detection and identification technologies for illicitly trafficked radioactive materials; response to detected cases and seized radioactive materials, strengthening of the awareness, training and exchange of information. The IAEA plans to issue the proceedings of this Conference containing the invited presentations, rapporteurs and Chairpersons overviews and summaries

  17. Safety of radiation sources and security of radioactive materials. Contributed papers

    International Nuclear Information System (INIS)

    1998-09-01

    The International Atomic Energy Agency (IAEA) in co-operation with the European Commission (EC), International Criminal Police Organization (INTERPOL) and the World Customs Organization (WCO) organized an International Conference on the Safety of Radiation Sources and the Security of Radioactive Materials, in Dijon, France, from 14 to 18 September 1998. The Government of France hosted this Conference through the Commissariat a l'energie atomique, Direction des applications militaires (CEA/DAM). This TECDOC contains the contributed papers dealing with the topics of this Conference which were accepted by the Conference Programme Committee for presentation. The papers written in one of the two working languages of the Conference, English or French are presented here each by a separate abstract. Ten technical sessions covered the following subjects: the regulatory control of radiation sources, including systems for notification, authorization and inspection; safety assessment techniques applied to radiation sources and design and technological measures including defense in depth and good engineering practice; managerial measures, including safety culture, human factors, quality assurance, qualified experts, training and education; learning from operational experience; international co-operation, including reporting systems and databases; verification of compliance, monitoring of compliance and assessment of the effectiveness of national programmes for the safety of sources; measures to prevent breaches in the security of radioactive materials, experience with criminal acts involving radioactive materials; detection and identification technologies for illicitly trafficked radioactive materials; response to detected cases and seized radioactive materials, strengthening of the awareness, training and exchange of information. The IAEA plans to issue the proceedings of this Conference containing the invited presentations, rapporteurs and Chairpersons overviews and summaries

  18. Novel particle and radiation sources and advanced materials

    Energy Technology Data Exchange (ETDEWEB)

    Mako, Frederick [FM Technologies, Inc. and Electron Technologies, Inc. (United States)

    2016-03-25

    The influence Norman Rostoker had on the lives of those who had the pleasure of knowing him is profound. The skills and knowledge I gained as a graduate student researching collective ion acceleration has fueled a career that has evolved from particle beam physics to include particle and radiation source development and advanced materials research, among many other exciting projects. The graduate research performed on collective ion acceleration was extended by others to form the backbone for laser driven plasma ion acceleration. Several years after graduate school I formed FM Technologies, Inc., (FMT), and later Electron Technologies, Inc. (ETI). Currently, as the founder and president of both FMT and ETI, the Rostoker influence can still be felt. One technology that we developed is a self-bunching RF fed electron gun, called the Micro-Pulse Gun (MPG). The MPG has important applications for RF accelerators and microwave tube technology, specifically clinically improved medical linacs and “green” klystrons. In addition to electron beam and RF source research, knowledge of materials and material interactions gained indirectly in graduate school has blossomed into breakthroughs in materials joining technologies. Most recently, silicon carbide joining technology has been developed that gives robust helium leak tight, high temperature and high strength joints between ceramic-to-ceramic and ceramic-to-metal. This joining technology has the potential to revolutionize the ethylene production, nuclear fuel and solar receiver industries by finally allowing for the practical use of silicon carbide as furnace coils, fuel rods and solar receptors, respectively, which are applications that have been needed for decades.

  19. Novel particle and radiation sources and advanced materials

    International Nuclear Information System (INIS)

    Mako, Frederick

    2016-01-01

    The influence Norman Rostoker had on the lives of those who had the pleasure of knowing him is profound. The skills and knowledge I gained as a graduate student researching collective ion acceleration has fueled a career that has evolved from particle beam physics to include particle and radiation source development and advanced materials research, among many other exciting projects. The graduate research performed on collective ion acceleration was extended by others to form the backbone for laser driven plasma ion acceleration. Several years after graduate school I formed FM Technologies, Inc., (FMT), and later Electron Technologies, Inc. (ETI). Currently, as the founder and president of both FMT and ETI, the Rostoker influence can still be felt. One technology that we developed is a self-bunching RF fed electron gun, called the Micro-Pulse Gun (MPG). The MPG has important applications for RF accelerators and microwave tube technology, specifically clinically improved medical linacs and “green” klystrons. In addition to electron beam and RF source research, knowledge of materials and material interactions gained indirectly in graduate school has blossomed into breakthroughs in materials joining technologies. Most recently, silicon carbide joining technology has been developed that gives robust helium leak tight, high temperature and high strength joints between ceramic-to-ceramic and ceramic-to-metal. This joining technology has the potential to revolutionize the ethylene production, nuclear fuel and solar receiver industries by finally allowing for the practical use of silicon carbide as furnace coils, fuel rods and solar receptors, respectively, which are applications that have been needed for decades.

  20. Novel particle and radiation sources and advanced materials

    Science.gov (United States)

    Mako, Frederick

    2016-03-01

    The influence Norman Rostoker had on the lives of those who had the pleasure of knowing him is profound. The skills and knowledge I gained as a graduate student researching collective ion acceleration has fueled a career that has evolved from particle beam physics to include particle and radiation source development and advanced materials research, among many other exciting projects. The graduate research performed on collective ion acceleration was extended by others to form the backbone for laser driven plasma ion acceleration. Several years after graduate school I formed FM Technologies, Inc., (FMT), and later Electron Technologies, Inc. (ETI). Currently, as the founder and president of both FMT and ETI, the Rostoker influence can still be felt. One technology that we developed is a self-bunching RF fed electron gun, called the Micro-Pulse Gun (MPG). The MPG has important applications for RF accelerators and microwave tube technology, specifically clinically improved medical linacs and "green" klystrons. In addition to electron beam and RF source research, knowledge of materials and material interactions gained indirectly in graduate school has blossomed into breakthroughs in materials joining technologies. Most recently, silicon carbide joining technology has been developed that gives robust helium leak tight, high temperature and high strength joints between ceramic-to-ceramic and ceramic-to-metal. This joining technology has the potential to revolutionize the ethylene production, nuclear fuel and solar receiver industries by finally allowing for the practical use of silicon carbide as furnace coils, fuel rods and solar receptors, respectively, which are applications that have been needed for decades.

  1. Recombination Narratives to Accompany "A-LM French One," First Edition.

    Science.gov (United States)

    Coughlin, Dorothy

    Supplementary recombination narratives intended for use with the 1961 edition of the text "A-LM French One" are designed to help students learn to manipulate basic textual materials. The sample narratives correlate with Units 4-14 of the text. The teacher is urged to make use of the overhead projector when using the narratives for the…

  2. High energy neutron source for materials research and development

    International Nuclear Information System (INIS)

    Odera, M.

    1989-01-01

    Requirements for neutron source for nuclear materials research are reviewed and ESNIT, Energy Selective Neutron Irradiation Test facility proposed by JAERI is discussed. Its principal aims of a wide neutron energy tunability and spectra peaking at each energy to enable characterization of material damage process are demanding but attractive goals which deserve detailed study. It is also to be noted that the requirements make a difference in facility design from those of FMIT, IFMIF and other high energy intense neutron sources built or planned to date. Areas of technologies to be addressed to realize the ESNIT facility are defined and discussed. In order to get neutron source having desired spectral characteristics keeping moderate intensity, projectile and target combinations must be examined including experimentation if necessary. It is also desired to minimize change of flux density and energy spectrum according to location inside irradiation chamber. Extended target or multiple targets configuration might be a solution as well as specimen rotation and choice of combination of projectile and target which has minimum velocity of the center of mass. Though relevant accelerator technology exists, it is to be stressed that considerable efforts must be paid, especially in the area of target and irradiation devices to get ESNIT goal. Design considerations to allow hands-on maintenance and future upgrading possibility are important either, in order to exploit the facility fully for nuclear materials research and development. (author)

  3. Light water reactor fuel analysis code FEMAXI-7. Model and structure [Revised edition

    International Nuclear Information System (INIS)

    Suzuki, Motoe; Udagawa, Yutaka; Amaya, Masaki; Saitou, Hiroaki

    2014-03-01

    A light water reactor fuel analysis code FEMAXI-7 has been developed for the purpose of analyzing the fuel behavior in both normal conditions and anticipated transient conditions. This code is an advanced version which has been produced by incorporating the former version FEMAXI-6 with numerous functional improvements and extensions. In FEMAXI-7, many new models have been added and parameters have been clearly arranged. Also, to facilitate effective maintenance and accessibility of the code, modularization of subroutines and functions have been attained, and quality comment descriptions of variables or physical quantities have been incorporated in the source code. With these advancements, the FEMAXI-7 code has been upgraded to a versatile analytical tool for high burnup fuel behavior analyses. This report is the revised edition of the first one which describes in detail the design, basic theory and structure, models and numerical method, and improvements and extensions. The first edition, JAEA-Data/Code 2010-035, was published in 2010. The first edition was extended by orderly addition and disposition of explanations of models and organized as the revised edition after three years interval. (author)

  4. Genetic mapping uncovers cis-regulatory landscape of RNA editing.

    Science.gov (United States)

    Ramaswami, Gokul; Deng, Patricia; Zhang, Rui; Anna Carbone, Mary; Mackay, Trudy F C; Li, Jin Billy

    2015-09-16

    Adenosine-to-inosine (A-to-I) RNA editing, catalysed by ADAR enzymes conserved in metazoans, plays an important role in neurological functions. Although the fine-tuning mechanism provided by A-to-I RNA editing is important, the underlying rules governing ADAR substrate recognition are not well understood. We apply a quantitative trait loci (QTL) mapping approach to identify genetic variants associated with variability in RNA editing. With very accurate measurement of RNA editing levels at 789 sites in 131 Drosophila melanogaster strains, here we identify 545 editing QTLs (edQTLs) associated with differences in RNA editing. We demonstrate that many edQTLs can act through changes in the local secondary structure for edited dsRNAs. Furthermore, we find that edQTLs located outside of the edited dsRNA duplex are enriched in secondary structure, suggesting that distal dsRNA structure beyond the editing site duplex affects RNA editing efficiency. Our work will facilitate the understanding of the cis-regulatory code of RNA editing.

  5. Freeze drying method for preparing radiation source material

    International Nuclear Information System (INIS)

    Mosley, W.C. Jr.; Smith, P.K.

    1975-01-01

    A solution containing radioisotope and palladium values is atomized into an air flow entering a cryogenically cooled chamber where the solution is deposited on the chamber walls as a thin layer of frozen material. The solvent portion of the frozen material is sublimated into a cold trap by elevating the temperature within the chamber while withdrawing solvent vapors. The residual crystals are heated to provide a uniformly mixed powder of palladium metal and a refractory radioisotope compound. The powder is thereafter consolidated into a pellet and further shaped into rod, wire or sheet form for easy apportionment into individual radiation sources. (U.S.)

  6. Applications of pulsed energy sources and hydrodynamic response to materials science

    International Nuclear Information System (INIS)

    Perry, F.; Nelson, W.

    1993-01-01

    The dynamic response of materials to pulsed, relativistic electron beams was studied for materials science applications over two decades ago. Presently, intense light ion beams are being explored for materials science applications. These include the Ion Beam Surface Treatment (IBEST) of materials for producing stronger and more corrosion-resistant materials and the evaporative deposition of polycrystalline thin films. Laser sources are also being extensively utilized as pulsed energy sources in medical science and in clinical applications. In particular, laser-tissue interactions are being investigated for laser angioplasty and surgery as well as cancer therapy. The understanding of the energy deposition and hydrodynamic response of a wide range of materials is essential to the success of these applications. In order to address these materials science applications, the authors are utilizing and developing high quality, energy deposition-hydrodynamic code techniques which can aid in the design and interpretation of experiments. Consequently, the authors strongly encourage the development of 3-dimensional, species-selective diagnostic techniques, e.g. Resonant Holographic Interferometry Spectroscopy (RHIS), to be used in analyzing the ablation plume in the thin film deposition experiments. In this presentation they show the results and discuss the limitations of calculations for these materials applications. They also discuss the status of the RHIS diagnostic

  7. LabVIEW 8 student edition

    CERN Document Server

    Bishop, Robert H

    2007-01-01

    For courses in Measurement and Instrumentation, Electrical Engineering lab, and Physics and Chemistry lab. This revised printing has been updated to include new LabVIEW 8.2 Student Edition. National Instruments' LabVIEW is the defacto industry standard for test, measurement, and automation software solutions. With the Student Edition of LabVIEW, students can design graphical programming solutions to their classroom problems and laboratory experiments with software that delivers the graphical programming capabilites of the LabVIEW professional version. . The Student Edition is also compatible with all National Instruments data acquisition and instrument control hardware. Note: The LabVIEW Student Edition is available to students, faculty, and staff for personal educational use only. It is not intended for research, institutional, or commercial use. For more information about these licensing options, please visit the National Instruments website at (http:www.ni.com/academic/)

  8. Direct Visual Editing of Node Attributes in Graphs

    Directory of Open Access Journals (Sweden)

    Christian Eichner

    2016-10-01

    Full Text Available There are many expressive visualization techniques for analyzing graphs. Yet, there is only little research on how existing visual representations can be employed to support data editing. An increasingly relevant task when working with graphs is the editing of node attributes. We propose an integrated visualize-and-edit approach to editing attribute values via direct interaction with the visual representation. The visualize part is based on node-link diagrams paired with attribute-dependent layouts. The edit part is as easy as moving nodes via drag-and-drop gestures. We present dedicated interaction techniques for editing quantitative as well as qualitative attribute data values. The benefit of our novel integrated approach is that one can directly edit the data while the visualization constantly provides feedback on the implications of the data modifications. Preliminary user feedback indicates that our integrated approach can be a useful complement to standard non-visual editing via external tools.

  9. Some high-current ion sources for materials modification

    International Nuclear Information System (INIS)

    Taylor, T.

    1989-01-01

    Ion sources for materials modification have evolved through three distinct generations. The first generation was adopted from research accelerators. These cold-cathode plasma-discharge devices generate beam currents of less than 100 μA. The hot-cathode plasma-discharge ion sources, originally developed for isotope separation, comprise the second generation. They produce between 100 μA and 10 mA of beam current. The third generation ion sources give beam currents in excess of 10 mA. This technology, transferred from industrial accelerators, has already made SIMOX (Separation by IMplanted OXygen) into a commercially viable semiconductor process and promises to do the same for ion implantation of metals and insulators. The author focuses on the third generation technology that will play a key role in the future of ion implantation. 10 refs.; 5 figs.; 2 tabs

  10. Editing modifies the GABA(A) receptor subunit alpha3

    DEFF Research Database (Denmark)

    Ohlson, Johan; Pedersen, Jakob Skou; Haussler, David

    2007-01-01

    Adenosine to inosine (A-to-I) pre-mRNA editing by the ADAR enzyme family has the potential to increase the variety of the proteome. This editing by adenosine deamination is essential in mammals for a functional brain. To detect novel substrates for A-to-I editing we have used an experimental method...... to find selectively edited sites and combined it with bioinformatic techniques that find stem-loop structures suitable for editing. We present here the first verified editing candidate detected by this screening procedure. We show that Gabra-3, which codes for the alpha3 subunit of the GABA(A) receptor......, is a substrate for editing by both ADAR1 and ADAR2. Editing of the Gabra-3 mRNA recodes an isoleucine to a methionine. The extent of editing is low at birth but increases with age, reaching close to 100% in the adult brain. We therefore propose that editing of the Gabra-3 mRNA is important for normal brain...

  11. The law for the regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1979-01-01

    The law aims to perform regulations on enterprises of refining, processing and reprocessing of nuclear source and fuel materials and on establishment and operation of reactors to realize the peaceful and deliberate utilization of atomic energy according to the principle of the atomic energy basic law. Regulations of use of internationally regulated substances are also envisaged to observe international agreements. Basic concepts and terms are defined, such as: atomic energy; nuclear fuel material; nuclear source material; reactor; refining; processing; reprocessing and internationally regulated substance. Any person besides the Power Reactor and Nuclear Fuel Material Developing Corporation who undertakes refining shall be designated by the Prime Minister and the Minister of International Trade and Industry. An application shall be filed to the ministers concerned, listing name and address of the person, name and location of the refining works, equipment and method of refining, etc. The permission of the Prime Minister is necessary for any person who engages in processing. An application shall be filed to the Prime Minister, listing name and address of the person, name and location of the processing works and equipment and method of processing, etc. Permission of the Prime Minister, the Minister of International Trade and Industry or the Minister of Transport is necessary for any person who sets up reactors. An application shall be filed to the minister concerned, listing name and address of the person, purpose of operation, style, thermal output of reactor and number of units, etc. (Okada, K.)

  12. Edix: A Software for Editing Algebraic Expressions.

    OpenAIRE

    Bouhineau , Denis; Nicaud , Jean-François; Pavard , X.

    2001-01-01

    International audience; The paper presents a computer software, called Edix, devoted to the edition of algebraic expressions in their usual 2D representation. At present, many systems display fine algebraic expressions, but the edition of such expressions is weak. Systems like Word and FrameMaker place sub-expressions in too many boxes so that many editing actions are not simple, while usual CAS (computer algebra systems) just use a 1D representation for the edition. Furthermore, Edix allows ...

  13. Safe transport of radioactive material. Second edition

    International Nuclear Information System (INIS)

    1996-01-01

    In 1991, the International Atomic Energy Agency published Training Course Series No. 1 (TCS-1), a training manual that provides in 20 chapters a detailed discussion of the background, philosophy, technical bases and requirements and implementation aspects of the Regulations for the Safe Transport of Radioactive Material. The Transport Regulations are widely implemented by the IAEA's Member States and are also used as the bases for radioactive material transport requirements of modal organisations such as the International Maritime Organization and the International Civil Aviation Organization. This document is a supplement of TCS-1 to provide additional material in the form of learning aids and new exercises, that have been developed with the use of TCS-1 at succeeding IAEA training courses. The learning aids in the first part of the supplement are hitherto unpublished material that provide detailed guidance useful in solving the exercises presented in the second part. Solutions to the exercises are on field at the IAEA Secretariat and are available by arrangement to lectures presenting IAEA training courses. 4 refs, 1 fig., 6 tabs

  14. Genome edited animals: Learning from GM crops?

    Science.gov (United States)

    Bruce, Ann

    2017-06-01

    Genome editing of livestock is poised to become commercial reality, yet questions remain as to appropriate regulation, potential impact on the industry sector and public acceptability of products. This paper looks at how genome editing of livestock has attempted to learn some of the lessons from commercialisation of GM crops, and takes a systemic approach to explore some of the complexity and ambiguity in incorporating genome edited animals in a food production system. Current applications of genome editing are considered, viewed from the perspective of past technological applications. The question of what is genome editing, and can it be considered natural is examined. The implications of regulation on development of different sectors of livestock production systems are studied, with a particular focus on the veterinary sector. From an EU perspective, regulation of genome edited animals, although not necessarily the same as for GM crops, is advocated from a number of different perspectives. This paper aims to open up new avenues of research on genome edited animals, extending from the current primary focus on science and regulation, to engage with a wider-range of food system actors.

  15. Government Contract Law (9th Edition)

    Science.gov (United States)

    1987-04-01

    This Ninth Edition, like its predecessors, will serve as the textbook for the Government Contract Law taught at the School of Systems and Logistics...drawn from Government Contract Law -Cases, 1987 edition, for a rounded approach to the subject. This edition of the text includes coverage of the...Government Contract Law complements the Federal Acquisition Regulation and provides a preventive law treatment for contracting personnel. While it may

  16. Marketing/Planning Library and Information Services. Second Edition.

    Science.gov (United States)

    Weingand, Darlene E.

    In the first edition of this book, the concepts of marketing and planning library and information services were presented as effective managerial strategies. Several paragraphs from the introduction to the first edition are reproduced, with author commentary, in this edition as an affirmation that the message is still true. In this second edition,…

  17. Catalogue of high-mass X-ray binaries in the Galaxy (4th edition)

    NARCIS (Netherlands)

    Liu, Q.Z.; van Paradijs, J.; van den Heuvel, E.P.J.

    2006-01-01

    We present a new edition of the catalogue of high-mass X-ray binaries in the Galaxy. The catalogue contains source name(s), coordinates, finding chart, X-ray luminosity, system parameters, and stellar parameters of the components and other characteristic properties of 114 high-mass X-ray binaries,

  18. Regulatory control of radiation sources and radioactive materials: The UK position

    International Nuclear Information System (INIS)

    Englefield, C.; Holyoak, B.; Ledgerwood, K.; Littlewood, K.

    2001-01-01

    The paper presents the organizations involved in the regulation of the safety of radiation sources and the security of radioactive materials across the UK. The safety of radiation sources is within the regulatory remit of the Health and Safety Executive, under the Health and safety of Work Act 1974 and associated regulations. Any employer using radiation sources has a statutory duty to comply with this legislation, thereby protecting workers and the public from undue risk. From a radioactive waste management perspective, the storage and use of radioactive materials and the accumulation and disposal of radioactive waste are regulated by the environment agencies of England and Wales, Scotland, and Northern Ireland, under the Radioactive Substances Act 1993. Special regulatory arrangements apply to nuclear sites, such as power stations and fuel cycle plants, and some additional bodies are involved in the regulation of the security of fissile materials. An explanation is given in the paper as to how these organizations to work together to provide a comprehensive and effective regulatory regime. An overview of how these regulators have recently started to work more closely with other enforcement bodies, such as the Police and Customs and Excise is also given, to illustrate the approach that is being applied in the UK to deal with orphan sources and illicit trafficking. (author)

  19. Language Adaptation for Extending Post-Editing Estimates for Closely Related Languages

    Directory of Open Access Journals (Sweden)

    Rios Miguel

    2016-10-01

    Full Text Available This paper presents an open-source toolkit for predicting human post-editing efforts for closely related languages. At the moment, training resources for the Quality Estimation task are available for very few language directions and domains. Available resources can be expanded on the assumption that MT errors and the amount of post-editing required to correct them are comparable across related languages, even if the feature frequencies differ. In this paper we report a toolkit for achieving language adaptation, which is based on learning new feature representation using transfer learning methods. In particular, we report performance of a method based on Self-Taught Learning which adapts the English-Spanish pair to produce Quality Estimation models for translation from English into Portuguese, Italian and other Romance languages using the publicly available Autodesk dataset.

  20. CrisprGE: a central hub of CRISPR/Cas-based genome editing.

    Science.gov (United States)

    Kaur, Karambir; Tandon, Himani; Gupta, Amit Kumar; Kumar, Manoj

    2015-01-01

    CRISPR system is a powerful defense mechanism in bacteria and archaea to provide immunity against viruses. Recently, this process found a new application in intended targeting of the genomes. CRISPR-mediated genome editing is performed by two main components namely single guide RNA and Cas9 protein. Despite the enormous data generated in this area, there is a dearth of high throughput resource. Therefore, we have developed CrisprGE, a central hub of CRISPR/Cas-based genome editing. Presently, this database holds a total of 4680 entries of 223 unique genes from 32 model and other organisms. It encompasses information about the organism, gene, target gene sequences, genetic modification, modifications length, genome editing efficiency, cell line, assay, etc. This depository is developed using the open source LAMP (Linux Apache MYSQL PHP) server. User-friendly browsing, searching facility is integrated for easy data retrieval. It also includes useful tools like BLAST CrisprGE, BLAST NTdb and CRISPR Mapper. Considering potential utilities of CRISPR in the vast area of biology and therapeutics, we foresee this platform as an assistance to accelerate research in the burgeoning field of genome engineering. © The Author(s) 2015. Published by Oxford University Press.

  1. Edition and visual culture: Brás Cubas and its multiple incarnations

    Directory of Open Access Journals (Sweden)

    Raquel Castedo

    2013-09-01

    Full Text Available The article has as an exemplary object the book of Machado de AssisMemórias Póstumas de Brás Cubas, published in different editions, to problematize the relations between texts and the materiality of the media that they are published. Evaluates the role of design as a praxis of editorial mediation, having in sight the scope of visual studies and reading practices. It is a theorical reflexion that has a foundation on bibliographical research and that appropriates reproductions of pages from different editions as visual arguments articulated with the debated topics. Also presents data about the ways of reading/access to the text obtained as a mean of questionary and interviews.

  2. Neutrons and synchrotron radiation in engineering materials science from fundamentals to applications

    CERN Document Server

    Schreyer, Andreas; Clemens, Helmut; Mayer, Svea

    2017-01-01

    Retaining its proven concept, the second edition of this ready reference specifically addresses the need of materials engineers for reliable, detailed information on modern material characterization methods. As such, it provides a systematic overview of the increasingly important field of characterization of engineering materials with the help of neutrons and synchrotron radiation. The first part introduces readers to the fundamentals of structure-property relationships in materials and the radiation sources suitable for materials characterization. The second part then focuses on such characterization techniques as diffraction and scattering methods, as well as direct imaging and tomography. The third part presents new and emerging methods of materials characterization in the field of 3D characterization techniques like three-dimensional X-ray diffraction microscopy. The fourth and final part is a collection of examples that demonstrate the application of the methods introduced in the first parts to probl...

  3. Social Science in Government: The Role of Policy Researchers. New Edition.

    Science.gov (United States)

    Nathan, Richard P.

    This substantially updated version of a book first published in 1988 tells the story of welfare reform in the United States over the past three decades, with an emphasis on contributions made by social scientists. This edition contains five new chapters with new case material to show how social science principles can be used in U.S. government. In…

  4. Human Germline Genome Editing

    OpenAIRE

    Ormond, Kelly E.; Mortlock, Douglas P.; Scholes, Derek T.; Bombard, Yvonne; Brody, Lawrence C.; Faucett, W. Andrew; Garrison, Nanibaa’ A.; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E.

    2017-01-01

    With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Gen...

  5. Official Study Guide for the Certified Park and Recreation Professional. Fourth Edition

    Science.gov (United States)

    Mulvaney, Michael A.; Hurd, Amy R.

    2013-01-01

    The "Official Study Guide for the CPRP Examination" provides up-to-date information in this new edition to assist the park and recreation professional in preparing for the CPRP examination. The study guide serves as an excellent source of information for any individual who works directly or indirectly in the field of park and recreation services.

  6. Scientific capabilities of the advanced light source for radioactive materials

    International Nuclear Information System (INIS)

    Shuh, D.K.

    2007-01-01

    The Advanced Light Source (ALS) of Lawrence Berkeley National Laboratory (LBNL) is a third-generation synchrotron radiation light source and is a U.S. Department of Energy (DOE) national user facility. Currently, the ALS has approximately forty-five operational beamlines spanning a spectrum of scientific disciplines, and provides scientific opportunities for more than 2 000 users a year. Access to the resources of the ALS is through a competitive proposal mechanism within the general user program. Several ALS beamlines are currently being employed for a range of radioactive materials investigations. These experiments are reviewed individually relying on a graded hazard approach implemented by the ALS in conjunction with the LBNL Environmental, Health, and Safety (EH and S) Radiation Protection Program. The ALS provides radiological work authorization and radiological control technician support and assistance for accepted user experimental programs. LBNL has several radioactive laboratory facilities located near the ALS that provide support for ALS users performing experiments with radioactive materials. The capabilities of the ALS beamlines for investigating radioactive materials are given and examples of several past studies are summarised. (author)

  7. The effect of using different sources of dry materials on waste-form grout properties

    International Nuclear Information System (INIS)

    Spence, R.D.; Gilliam, T.M.; McDaniel, E.W.

    1992-01-01

    A reference grout formulation had been developed for a liquid low-level radioactive waste using the following dry materials: ground limestone, ground granulated blast furnace slag, fly ash, and cement. The effect of varying the sources of these dry materials are tested. Two limestones, two fly ashes, two cements, and eight slags were tested. Varying the source of dry materials significantly affected the grout properties, but only the 28-d free-standing liquid varied outside of the preferred range. A statistical technique, Tukey's paired comparison, can be used to ascertain whether a given combination of dry materials resulted in grout properties significantly different from those of other combinations of dry materials

  8. Publication Manual of the American Psychological Association--5th edition: a review of additions and changes in style requirements.

    Science.gov (United States)

    Russell, Cynthia L; Aud, Myra A

    2002-01-01

    The purpose of this article is to highlight the substantive changes and enhancements between the 4th edition and new 5th edition of the so that modifications and enhancements are more easily incorporated into the reader's writing and editing practice. The 4th and new 5th editions of the were compared and substantive changes are presented. The following text style requirements are addressed: (a) use of parentheses to enclose statistical values, (b) use of italics, and (c) presentation of statistical data. Reference citation style changes include: (a) use of italics instead of underlining, (b) use of et al., and (c) use of the hanging indent. With the explosion of electronic media use, guidelines for documenting these sources are reviewed. Appropriate use of adverbs and research subject descriptors, submission of manuscripts on disks or files, responsibilities of corresponding authors, and converting the dissertation into a journal article are addressed. This information should assist the reader to quickly and accurately focus upon the enhancements and changes in the recently released 5th edition. Hopefully these changes will easily be incorporated into the readers' editing responsibilities, manuscripts, and subsequent publications.

  9. Bindings and covers of Cyrillic old printed editions of Holy Dormition Pochayiv Lavra publishing house

    Directory of Open Access Journals (Sweden)

    Zheleznyak O.

    2014-01-01

    Full Text Available The article observes bindings and covers of Holy Dormition Pochayiv monastery publishing house editions. On the basis of copies from V. Vernadsky National Library of Ukraine fonds the covering material and decoration (centerpieces, ornaments, corner pieces of Pochayiv editions covers are analyzed. Besides that, distinctive features of Pochaiv publishing house bindings and covers are defined and described. Description of bindings enabled us to find bookbinder’s chiches, which had often been put on bottom endleafs. Special attention in the article is paid to highly artistic decoration of Pochayiv publishing house bindings of Altar Gospels. In the eighties of 18th century Pochayiv publishing house printed books, ordered by Old Believers. As a rule Old Believers editions derive all their compositional elements from books of 17th century, published before the reform. Bindings of Pochayiv Old Believers editions, distinctive for its modest decoration, are not exception of this rule. Besides that, Pochayiv old printed books were sometimes binded in covers made by Kyiv Pechersk Lavra craftsmen. Centerpieces of these covers sometimes contain the image of Kyiv Holy Dormition cathedral.

  10. Writing, Proofreading and Editing in Information Theory

    Directory of Open Access Journals (Sweden)

    J. Ricardo Arias-Gonzalez

    2018-05-01

    Full Text Available Information is a physical entity amenable to be described by an abstract theory. The concepts associated with the creation and post-processing of the information have not, however, been mathematically established, despite being broadly used in many fields of knowledge. Here, inspired by how information is managed in biomolecular systems, we introduce writing, entailing any bit string generation, and revision, as comprising proofreading and editing, in information chains. Our formalism expands the thermodynamic analysis of stochastic chains made up of material subunits to abstract strings of symbols. We introduce a non-Markovian treatment of operational rules over the symbols of the chain that parallels the physical interactions responsible for memory effects in material chains. Our theory underlies any communication system, ranging from human languages and computer science to gene evolution.

  11. Order for execution of the law concerning regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1978-01-01

    Under the above mentioned law this order prescribes the procedures of controls given to the persons who wish to conduct refining and fabricating businesses, to construct and operate reactors, and to use nuclear source materials, nuclear fuel materials and internationally controlled materials. The common controlling principle prescribed is that the permission or authorization necessary for above listed businesses should be applied for at each factory or each place of business. Based on the principle, the order prescribes: the procedures to apply for the authorization of the refining business, the permission of the change thereof, and the permission of the fabricating business and the change, thereof (the 1st chapter); the procedures to apply for the permission of the construction of reactors and of the change of the construction, as well as the procedure to do periodic inspections of reactor facilities (the 2nd chapter); the procedures to apply for the permission to use nuclear fuel materials and to change the use thereof, the submission of the report to use nuclear source materials, as well as the procedure to apply for the permission to use internationally controlled materials. In the 4th chapter the order lists up the items on which the competent Ministers may require reports from the person who carries on the relevant business. (Matsushima, A.)

  12. The commercialization of genome-editing technologies.

    Science.gov (United States)

    Brinegar, Katelyn; K Yetisen, Ali; Choi, Sun; Vallillo, Emily; Ruiz-Esparza, Guillermo U; Prabhakar, Anand M; Khademhosseini, Ali; Yun, Seok-Hyun

    2017-11-01

    The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from basic research to translational medicine. In our analyses, we evaluated the patent landscape of gene-editing technologies and found that in comparison to earlier gene-editing techniques, CRISPR has gained significant traction and this has established dominance. Although most of the gene-editing technologies originated from the industry, CRISPR has been pioneered by academic research institutions. The spinout of CRISPR biotechnology companies from academic institutions demonstrates a shift in entrepreneurship strategies that were previously led by the industry. These academic institutions, and their subsequent companies, are competing to generate comprehensive intellectual property portfolios to rapidly commercialize CRISPR products. Our analysis shows that the emergence of CRISPR has resulted in a fivefold increase in genome-editing bioenterprise investment over the last year. This entrepreneurial movement has spurred a global biotechnology revolution in the realization of novel gene-editing technologies. This global shift in bioenterprise will continue to grow as the demand for personalized medicine, genetically modified crops and environmentally sustainable biofuels increases. However, the monopolization of intellectual property, negative public perception of genetic engineering and ambiguous regulatory policies may limit the growth of these market segments.

  13. US Hazardous Materials Routes, Geographic WGS84, BTS (2006) [hazardous_material_routes_BTS_2006

    Data.gov (United States)

    Louisiana Geographic Information Center — The Federal Motor Carrier Safety Administration (FMCSA) Hazardous Material Routes were developed using the 2004 First Edition TIGER/Line files. The routes are...

  14. Validation of the fifth edition BI-RADS ultrasound lexicon with comparison of fourth and fifth edition diagnostic performance using video clips

    International Nuclear Information System (INIS)

    Yoon, Jung Hyun; Kim, Min Jung; Lee, Hye Sun; Kim, Sung Hun; Youk, Ji Hyun; Jeong, Sun Hye; Kim, You Me

    2016-01-01

    The aim of this study was to evaluate the positive predictive value (PPV) and the diagnostic performance of the ultrasonographic descriptors in the fifth edition of BI-RADS, comparing with the fourth edition using video clips. From September 2013 to July 2014, 80 breast masses in 74 women (mean age, 47.5±10.7 years) from five institutions of the Korean Society of Breast Imaging were included. Two radiologists individually reviewed the static and video images and analyzed the images according to the fourth and fifth edition of BI-RADS. The PPV of each descriptor was calculated and diagnostic performances between the fourth and fifth editions were compared. Of the 80 breast masses, 51 (63.8%) were benign and 29 (36.2%) were malignant. Suspicious ultrasonographic features such as irregular shape, non-parallel orientation, angular or spiculated margins, and combined posterior features showed higher PPV in both editions (all P<0.05). No significant differences were found in the diagnostic performances between the two editions (all P>0.05). The area under the receiver operating characteristics curve was higher in the fourth edition (0.708 to 0.690), without significance (P=0.416). The fifth edition of the BI-RADS ultrasound lexicon showed comparable performance to the fourth edition and can be useful in the differential diagnosis of breast masses using ultrasonography

  15. Operational Transformation In Co-Operative Editing

    Directory of Open Access Journals (Sweden)

    Mandeep Kaur

    2015-08-01

    Full Text Available Cooperative Editing Systems in real-time allows a virtual team to view and edit a shared document at the same time. The document shared must be synchronized in order to ensure consistency for all the participants. This paper describes the Operational Transformation the evolution of its techniques its various applications major issues and achievements. In addition this paper will present working of a platform where two users can edit a code programming file at the same time.

  16. Research activities on structure materials of spallation neutron source at SINQ

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, G.S.; Dai, Y. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    With the growing interests on powerful spallation neutron sources, especially with liquid metal targets, and accelerator driven energy systems, spallation materials science and technology have been received wide attention. At SINQ, material research activities are focused on: a) liquid metal corrosion; b) radiation damage; and c) interaction of corrosion and radiation damage. (author) 1 fig., refs.

  17. An examination of source material requirements contained in 10 CFR Part 40

    International Nuclear Information System (INIS)

    Nussbaumer, D.; Smith, D.A.; Wiblin, C.

    1992-10-01

    This report identifies issues for consideration for rule-making to update the requirements for source material in 10 CFR Part 40 and examines options for resolving these issues. The contemplated rulemaking is intended to update 10 CFR Part 40 to reflect current radiation protection principles and regulatory practices. It is expected that such an update would make requirements for the control of source material more comparable to those pertaining to byproduct material contained in 10 CFR Part 30. The newer biological data and dose calculation methodology reflected in revised 10 CFR Part 20 will be used in analyses of potential regulatory amendments. This report presents historical background information and discussion on the various issues identified and makes preliminary recommendations concerning needed regulatory changes and approaches to rulemaking

  18. Environmental cleanup privatization, products and services directory, January 1997. Second edition

    International Nuclear Information System (INIS)

    1997-01-01

    The US Department of Energy has undertaken an ambitious ''Ten Year Plan'' for the Weapons Complex, an initiative to complete cleanup at most nuclear sites within a decade. This Second Edition of the Directory is designed to facilitate privatization which is key to the success of the Plan. The Directory is patterned after the telephone Yellow Pages. Like the Yellow Pages, it provides the user with points of contact for inquiring further into the capabilities of the listed companies. This edition retains the original format of three major sections under the broad headings: Treatment, Characterization, and Extraction/Deliver/Materials Handling. Within each section, companies are listed alphabetically. Also, ''company name'' and ''process type'' indices are provided at the beginning of each section to allow the user quick access to listings of particular interest

  19. Environmental cleanup privatization, products and services directory, January 1997. Second edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The US Department of Energy has undertaken an ambitious ``Ten Year Plan`` for the Weapons Complex, an initiative to complete cleanup at most nuclear sites within a decade. This Second Edition of the Directory is designed to facilitate privatization which is key to the success of the Plan. The Directory is patterned after the telephone Yellow Pages. Like the Yellow Pages, it provides the user with points of contact for inquiring further into the capabilities of the listed companies. This edition retains the original format of three major sections under the broad headings: Treatment, Characterization, and Extraction/Deliver/Materials Handling. Within each section, companies are listed alphabetically. Also, ``company name`` and ``process type`` indices are provided at the beginning of each section to allow the user quick access to listings of particular interest.

  20. The levels of edit. [technical writing in science

    Science.gov (United States)

    Vanburen, R.; Buehler, M. F.; Wallenbrock, D. (Editor)

    1976-01-01

    The editorial process is analyzed, and five levels of edit are identified. These levels represent cumulative combinations of nine types of edit: (1) coordination, (2) policy, (3) integrity, (4) screening, (5) copy clarification, (6) Mechanical Style, (7) Language, and (9) substantive. The levels and types of edit, although developed for specific use with external reports at the Jet Propulsion Laboratory, cover the general range of technical editing, especially as it applies to an in-house technical publications organization. Each type of edit is set forth in terms of groups of actions to be performed by the editor. The edit-level concept has enhanced understanding and communication among editors, authors, and publications managers concerning the specific editorial work to be done on each manuscript. It has also proved useful as a management tool for estimating and monitoring cost.

  1. Reducing risk and accelerating delivery of a neutron source for fusion materials research

    Energy Technology Data Exchange (ETDEWEB)

    Surrey, E., E-mail: Elizabeth.Surrey@ccfe.ac.uk [EURATOM/CCFE, Abingdon OX14 3DB (United Kingdom); Porton, M. [EURATOM/CCFE, Abingdon OX14 3DB (United Kingdom); Davenne, T.; Findlay, D.; Letchford, A.; Thomason, J. [STFC Rutherford Appleton Laboratory, Harwell OX11 0QX (United Kingdom); Roberts, S.G.; Marrow, J.; Seryi, A. [University of Oxford, Oxford OX1 3DP (United Kingdom); Connolly, B. [University of Birmingham, Edgbaston B15 2TT (United Kingdom); Owen, H. [University of Manchester, Manchester M13 9PL (United Kingdom)

    2014-04-15

    Highlights: • Proposed neutron source for fusion materials – FAFNIR – n(d,C) stripping source. • Near term technology, reduces risk compared with IFMIF, timely data production. • Technical, economic and programme needs assessed, compatible with EU Roadmap proposals. • Safety case impacts regulatory role for source, now mainly stakeholder insurance. - Abstract: The materials engineering database relevant to fusion irradiation is poorly populated and it has long been recognized that a fusion spectrum neutron source will be required, the facility IFMIF being the present proposal. Re-evaluation of the regulatory approach for the EU proposed DEMO device shows that the purpose of the source can be changed from lifetime equivalent irradiation exposure to data generation at lower levels of exposure by adopting a defence in depth strategy and regular component surveillance. This reduces the specification of the source with respect to IFMIF allowing lower risk technology solutions to be considered. A description of such a source, the Facility for Fusion Neutron Irradiation Research, FAFNIR, is presented here along with project timescales and costs.

  2. The effect of using different sources of dry materials on waste-form grout properties

    International Nuclear Information System (INIS)

    Spence, R.D.; Gilliam, T.M.; McDaniel, E.W.

    1992-01-01

    A reference grout formulation had been developed for a liquid low-level radioactive waste using the following dry materials: ground limestone, ground granulated blast furnace slag, fly ash, and cement. The effect of varying the sources of these dry materials was tested. Two limestones, two fly ashes, two cements, and eight slags were tested. Varying the source of dry materials significantly affected the grout properties, but only the 28-d free-standing liquid varied outside of the preferred range. A statistical technique, Tukey's paired comparison, can be used to ascertain whether a given combination of dry materials resulted in grout properties significantly different from those of other combinations of dry materials. (author)

  3. Possibility of using sources of vacuum ultraviolet irradiation to solve problems of space material science

    Science.gov (United States)

    Verkhoutseva, E. T.; Yaremenko, E. I.

    1974-01-01

    An urgent problem in space materials science is simulating the interaction of vacuum ultraviolet (VUV) of solar emission with solids in space conditions, that is, producing a light source with a distribution that approximates the distribution of solar energy. Information is presented on the distribution of the energy flux of VUV of solar radiation. Requirements that must be satisfied by the VUV source used for space materials science are formulated, and a critical evaluation is given of the possibilities of using existing sources for space materials science. From this evaluation it was established that none of the sources of VUV satisfies the specific requirements imposed on the simulator of solar radiation. A solution to the problem was found to be in the development of a new type of source based on exciting a supersonic gas jet flowing into vacuum with a sense electron beam. A description of this gas-jet source, along with its spectral and operation characteristics, is presented.

  4. Validation of the fifth edition BI-RADS ultrasound lexicon with comparison of fourth and fifth edition diagnostic performance using video clips

    Directory of Open Access Journals (Sweden)

    Jung Hyun Yoon

    2016-10-01

    Full Text Available Purpose The aim of this study was to evaluate the positive predictive value (PPV and the diagnostic performance of the ultrasonographic descriptors in the fifth edition of BI-RADS, comparing with the fourth edition using video clips. Methods From September 2013 to July 2014, 80 breast masses in 74 women (mean age, 47.5±10.7 years from five institutions of the Korean Society of Breast Imaging were included. Two radiologists individually reviewed the static and video images and analyzed the images according to the fourth and fifth edition of BI-RADS. The PPV of each descriptor was calculated and diagnostic performances between the fourth and fifth editions were compared. Results Of the 80 breast masses, 51 (63.8% were benign and 29 (36.2% were malignant. Suspicious ultrasonographic features such as irregular shape, non-parallel orientation, angular or spiculated margins, and combined posterior features showed higher PPV in both editions (all P0.05. The area under the receiver operating characteristics curve was higher in the fourth edition (0.708 to 0.690, without significance (P=0.416. Conclusion The fifth edition of the BI-RADS ultrasound lexicon showed comparable performance to the fourth edition and can be useful in the differential diagnosis of breast masses using ultrasonography.

  5. Book Review: New Perspectives on Technical Editing

    Science.gov (United States)

    Murphy, A. J. (Ed.); Sterken, Christiaan

    2012-08-01

    New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

  6. Asteroids. Prospective energy and material resources

    Energy Technology Data Exchange (ETDEWEB)

    Badescu, Viorel (ed.) [Bucharest Polytechnic Univ. (Romania). Candida Oancea Institute

    2013-11-01

    Recent research on Prospective Energy and Material Resources on Asteroids. Carefully edited book dedicated to Asteroids prospective energy and material resources. Written by leading experts in the field. The Earth has limited material and energy resources while these resources in space are virtually unlimited. Further development of humanity will require going beyond our planet and exploring of extraterrestrial resources and sources of unlimited power. Thus far, all missions to asteroids have been motivated by scientific exploration. However, given recent advancements in various space technologies, mining asteroids for resources is becoming ever more feasible. A significant portion of asteroids value is derived from their location; the required resources do not need to be lifted at a great expense from the surface of the Earth. Resources derived from Asteroid not only can be brought back to Earth but could also be used to sustain human exploration of space and permanent settlements in space. This book investigates asteroids' prospective energy and material resources. It is a collection of topics related to asteroid exploration, and utilization. It presents past and future technologies and solutions to old problems that could become reality in our life time. The book therefore is a great source of condensed information for specialists involved in current and impending asteroid-related activities and a good starting point for space researchers, inventors, technologists and potential investors. Written for researchers, engineers, and businessmen interested in asteroids' exploration and exploitation.

  7. Editorial Bias in Crowd-Sourced Political Information.

    Directory of Open Access Journals (Sweden)

    Joshua L Kalla

    Full Text Available The Internet has dramatically expanded citizens' access to and ability to engage with political information. On many websites, any user can contribute and edit "crowd-sourced" information about important political figures. One of the most prominent examples of crowd-sourced information on the Internet is Wikipedia, a free and open encyclopedia created and edited entirely by users, and one of the world's most accessed websites. While previous studies of crowd-sourced information platforms have found them to be accurate, few have considered biases in what kinds of information are included. We report the results of four randomized field experiments that sought to explore what biases exist in the political articles of this collaborative website. By randomly assigning factually true but either positive or negative and cited or uncited information to the Wikipedia pages of U.S. senators, we uncover substantial evidence of an editorial bias toward positivity on Wikipedia: Negative facts are 36% more likely to be removed by Wikipedia editors than positive facts within 12 hours and 29% more likely within 3 days. Although citations substantially increase an edit's survival time, the editorial bias toward positivity is not eliminated by inclusion of a citation. We replicate this study on the Wikipedia pages of deceased as well as recently retired but living senators and find no evidence of an editorial bias in either. Our results demonstrate that crowd-sourced information is subject to an editorial bias that favors the politically active.

  8. Editorial Bias in Crowd-Sourced Political Information.

    Science.gov (United States)

    Kalla, Joshua L; Aronow, Peter M

    2015-01-01

    The Internet has dramatically expanded citizens' access to and ability to engage with political information. On many websites, any user can contribute and edit "crowd-sourced" information about important political figures. One of the most prominent examples of crowd-sourced information on the Internet is Wikipedia, a free and open encyclopedia created and edited entirely by users, and one of the world's most accessed websites. While previous studies of crowd-sourced information platforms have found them to be accurate, few have considered biases in what kinds of information are included. We report the results of four randomized field experiments that sought to explore what biases exist in the political articles of this collaborative website. By randomly assigning factually true but either positive or negative and cited or uncited information to the Wikipedia pages of U.S. senators, we uncover substantial evidence of an editorial bias toward positivity on Wikipedia: Negative facts are 36% more likely to be removed by Wikipedia editors than positive facts within 12 hours and 29% more likely within 3 days. Although citations substantially increase an edit's survival time, the editorial bias toward positivity is not eliminated by inclusion of a citation. We replicate this study on the Wikipedia pages of deceased as well as recently retired but living senators and find no evidence of an editorial bias in either. Our results demonstrate that crowd-sourced information is subject to an editorial bias that favors the politically active.

  9. The IAEA transport regulations: main modifications included in the 1996 edition and the possible impact of its adoption in Argentina

    International Nuclear Information System (INIS)

    Lopez Vietri, J.R.; Novo, R.G.; Bianchi, A.J.

    1998-01-01

    Full text: This paper points out a comparative analysis between the requirements of the 1985 edition (as Amended 1990), in-force in almost all countries included Argentina, and the 1996 edition, that is foresee to put in-force 1st January 2001, of the Regulations for the safe transport of radioactive material, published by the International Atomic Energy Agency (IAEA). The English version of the 1996 edition was published in December 1996 and the Spanish one in September 1997. Such edition was the culmination of a difficult consensus and harmonisation reached after an analysis process of the-years cycle between the IAEA Member Sates and related international organisations (United Nations, International Civil Aviation Organisation, International Air Transport Association, International Federation of Air Lines Pilots Associations, International Maritime Organisation) as well as regional organisations (Economic Commission for Europe, Commission of the European Communities). Both editions of the Regulations include a set of design, operational and administrative requirements that substantially do not differ as for their safety basic philosophy. However, the 1996 edition introduces numerous modifications of different magnitude, which will derive in technological, economic and operative consequences. Of such modifications the paper only analysed the relevant ones which update the state of art in the subject and allow the Regulations continue maintaining an acceptable level of control of the radiation, criticality and thermal hazards to persons, property and the environment during the transport of radioactive material. In addition, the paper briefly describes the possible impact that the main modifications induced in the 1996 edition of the Regulations should have, depending on the type of user considered either in Argentina or in other Latin America countries. However, it is desirable that the personal of competent authorities of each country involved in transport

  10. EDITAR: a module for reaction rate editing and cross-section averaging within the AUS neutronics code system

    International Nuclear Information System (INIS)

    Robinson, G.S.

    1986-03-01

    The EDITAR module of the AUS neutronics code system edits one and two-dimensional flux data pools produced by other AUS modules to form reaction rates for materials and their constituent nuclides, and to average cross sections over space and energy. The module includes a Bsub(L) flux calculation for application to cell leakage. The STATUS data pool of the AUS system is used to enable the 'unsmearing' of fluxes and nuclide editing with minimal user input. The module distinguishes between neutron and photon groups, and printed reaction rates are formed accordingly. Bilinear weighting may be used to obtain material reactivity worths and to average cross sections. Bilinear weighting is at present restricted to diffusion theory leakage estimates made using mesh-average fluxes

  11. Ukrainian efforts in preventing illicit trafficking in nuclear materials and other radioactive sources

    International Nuclear Information System (INIS)

    Kondratov, S.I.

    1998-01-01

    The Ukrainian efforts in preventing illicit trafficking in nuclear materials and other radioactive sources are described. Attention is paid for Ukrainian Government's Decree intended, in particular, to facilitate in establishing well-coordinated activities of the Ukrainian law enforcement bodies and other agencies involved, assigning the status of the main expert organization on illicit trafficking in nuclear materials to the Scientific Center 'Institute for Nuclear Research', in developing the three-years Program on prevention illicit trafficking in nuclear materials and other radioactive sources on the Ukrainian territory as well as measures at the State and customs borders. The main directions provided by the draft Program mentioned are presented as well. (author)

  12. Materials considerations for the National Spallation Neutron Source target

    International Nuclear Information System (INIS)

    Mansur, L.K.; DiStefano, J.R.; Farrell, K.; Lee, E.H.; Pawel, S.J.; Wechsler, M.S.

    1997-08-01

    The National Spallation Neutron Source (NSNS), in which neutrons are generated by bombarding a liquid mercury target with 1 GeV protons, will place extraordinary demands on materials performance. The target structural material will operate in an aggressive environment, subject to intense fluxes of high energy protons, neutrons, and other particles, while exposed to liquid mercury and to water. Components that require special consideration include the Hg liquid target container and protective shroud, beam windows, support structures, moderator containers, and beam tubes. In response to these demands a materials R and D program has been developed for the NSNS that includes: selection of materials; calculations of radiation damage; irradiations, post irradiation testing, and characterization; compatibility testing and characterization; design and implementation of a plan for monitoring of materials performance in service; and materials engineering and technical support to the project. Irradiations are being carried out in actual and simulated spallation environments. Compatibility experiments in Hg are underway to ascertain whether the phenomena of liquid metal embrittlement and temperature gradient mass transfer will be significant. Results available to date are assessed in terms of the design and operational performance of the facility

  13. Assessment of the threat from diverted radioactive material and 'orphan sources' - An international comparison

    International Nuclear Information System (INIS)

    Steinhausler, F.

    2001-01-01

    Full text: Multiple international activities have been undertaken to contain the trafficking of weapons-usable material in order to reduce the risk from the proliferation of such material. In addition, over the past decade the issue of unintended handling and transport of radioactive material has become increasingly important. Concurrent with the growing number of radioactive sources in industry, medicine, agriculture and research, the probability for losing control over such sources increases as well ('orphan sources'). The potential impact on society and the environment from these two categories of threat has been documented extensively in the literature. In this study representatives from 11 countries in the Americas, Europe and Asia-Pacific formed a network to exchange information concerning nuclear and other radioactive material on the following topic areas: Legislation and regulatory practices for the production, processing, handling, use, holding, storage, transport, import, and export; History of site-specific non-compliance and enforcement actions, as well as punitive actions; National approach for handling the issue of orphan sources; The role of national security forces; Managerial and technical procedures to ensure material inventory control and accountancy; Aspects of physical protection on-site and during transport; Technical/scientific expertise and equipment available at the national level to detect, identify and quantify such material in the field; Level of practical implementation of technical equipment to detect such material at border crossings, airports, railway stations, and mail distribution centres; Cases of seizure of nuclear and contaminated materials, illegal sales and fraud; Training programmes available for preventing, detecting and responding to the loss of control. The results of the analysis show that, despite several international consensus documents and supporting legislation, in several cases major additional efforts are needed

  14. Radiation sources safety and radioactive materials security regulation in Ukraine

    International Nuclear Information System (INIS)

    Smyshliaiev, A.; Holubiev, V.; Makarovska, O.

    2001-01-01

    packages for shipment of radiation sources; State registration of radiation sources; licensing of radiation material transportation. In 1997, the Government of Ukraine decided to establish a unified computerized system of accountancy, control and registration of radiation sources - the State Register of Radiation Sources (Register). In 1998, under the Ukrainian State Production Enterprise 'Isotope' a separate subdivision 'State Register of Radiation Sources' was established. This subdivision functions as the main registration centre, and has been supplied with computer equipment with the assistance of the IAEA. During 1999-2000, the basic documents that regulate the legal status of the Register, the radiation source registration procedure and the State inventory of radiation source procedure were developed and approved by the relevant ministries. Urgent commissioning of the Register and starting the State registration of radiation sources will form a good basis for considerable upgrading of the level of safety and security of radiation sources, reduction of illicit trafficking in radiation sources, and investigation of illicit trafficking cases. Lack of funds is the main problem impeding the commissioning of the Register. On the basis of analysis of safety regulation system for activities dealing with radiation sources in Ukraine, we can draw a conclusion about its sufficiency for effective safety regulation of radiation sources and security of radioactive materials. (author)

  15. CRISPR-Cas9-Based Genome Editing of Human Induced Pluripotent Stem Cells.

    Science.gov (United States)

    Giacalone, Joseph C; Sharma, Tasneem P; Burnight, Erin R; Fingert, John F; Mullins, Robert F; Stone, Edwin M; Tucker, Budd A

    2018-02-28

    Human induced pluripotent stem cells (hiPSCs) are the ideal cell source for autologous cell replacement. However, for patients with Mendelian diseases, genetic correction of the original disease-causing mutation is likely required prior to cellular differentiation and transplantation. The emergence of the CRISPR-Cas9 system has revolutionized the field of genome editing. By introducing inexpensive reagents that are relatively straightforward to design and validate, it is now possible to correct genetic variants or insert desired sequences at any location within the genome. CRISPR-based genome editing of patient-specific iPSCs shows great promise for future autologous cell replacement therapies. One caveat, however, is that hiPSCs are notoriously difficult to transfect, and optimized experimental design considerations are often necessary. This unit describes design strategies and methods for efficient CRISPR-based genome editing of patient- specific iPSCs. Additionally, it details a flexible approach that utilizes positive selection to generate clones with a desired genomic modification, Cre-lox recombination to remove the integrated selection cassette, and negative selection to eliminate residual hiPSCs with intact selection cassettes. © 2018 by John Wiley & Sons, Inc. Copyright © 2018 John Wiley & Sons, Inc.

  16. Interactive Editing and Cataloging Interfaces for Modern Digital Library Systems

    CERN Document Server

    Raae, L C; Helstrup, H

    2009-01-01

    The next-generation High Energy Physics information system, INSPIRE, is being built by combining the content from the successful SPIRES database of bibliographic information with the CDS Invenio software being developed at CERN, an open-source platform for large digital library systems. The project is a collaboration between four major particle physics laboratories in Europe and the U.S. New tools are being developed to enable the global cooperation between catalogers at these labs. The BibEdit module will provide a central interface for the editing, enrichment, correction and verification of a record on its way into the system, by processing and presenting data from several supporting modules to the cataloger. The objective is to minimize the time and actions needed by the cataloger to process the record. To create a fast and powerful web application we make use of modern AJAX technology to create a dynamic and responsive user interface, where server communication happens in the background without delaying t...

  17. Can Concentration - Discharge Relationships Diagnose Material Source During Extreme Events?

    Science.gov (United States)

    Karwan, D. L.; Godsey, S.; Rose, L.

    2017-12-01

    Floods can carry >90% of the basin material exported in a given year as well as alter flow pathways and material sources. In turn, sediment and solute fluxes can increase flood damages and negatively impact water quality and integrate physical and chemical weathering of landscapes and channels. Concentration-discharge (C-Q) relationships are used to both describe export patterns as well as compute them. Metrics for describing C-Q patterns and inferring their controls are vulnerable to infrequent sampling that affects how C-Q relationships are interpolated and interpreted. C-Q relationships are typically evaluated from multiple samples, but because hydrological extremes are rare, data are often unavailable for extreme events. Because solute and sediment C-Q relationships likely respond to changes in hydrologic extremes in different ways, there is a pressing need to define their behavior under extreme conditions, including how to properly sample to capture these patterns. In the absence of such knowledge, improving load estimates in extreme floods will likely remain difficult. Here we explore the use of C-Q relationships to determine when an event alters a watershed system such that it enters a new material source/transport regime. We focus on watersheds with sediment and discharge time series include low-frequency and/or extreme events. For example, we compare solute and sediment patterns in White Clay Creek in southeastern Pennsylvania across a range of flows inclusive of multiple hurricanes for which we have ample ancillary hydrochemical data. TSS is consistently mobilized during high flow events, even during extreme floods associated with hurricanes, and sediment fingerprinting indicates different sediment sources, including in-channel remobilization and landscape erosion, are active at different times. In other words, TSS mobilization in C-Q space is not sensitive to the source of material being mobilized. Unlike sediments, weathering solutes in this watershed

  18. Depfix, a Tool for Automatic Rule-based Post-editing of SMT

    Directory of Open Access Journals (Sweden)

    Rudolf Rosa

    2014-09-01

    Full Text Available We present Depfix, an open-source system for automatic post-editing of phrase-based machine translation outputs. Depfix employs a range of natural language processing tools to obtain analyses of the input sentences, and uses a set of rules to correct common or serious errors in machine translation outputs. Depfix is currently implemented only for English-to-Czech translation direction, but extending it to other languages is planned.

  19. Calculations of radiation damage in target, container and window materials for spallation neutron sources

    International Nuclear Information System (INIS)

    Wechsler, M.S.; Mansur, L.K.

    1996-01-01

    Radiation damage in target, container, and window materials for spallation neutron sources is am important factor in the design of target stations for accelerator-driver transmutation technologies. Calculations are described that use the LAHET and SPECTER codes to obtain displacement and helium production rates in tungsten, 316 stainless steel, and Inconel 718, which are major target, container, and window materials, respectively. Results are compared for the three materials, based on neutron spectra for NSNS and ATW spallation neutron sources, where the neutron fluxes are normalized to give the same flux of neutrons of all energies

  20. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 1998 edition

    International Nuclear Information System (INIS)

    1998-08-01

    The information contained in this report is given in six tables. Tables 1 to 4 present administrative data including issue and expiration dates, package identification, package serial numbers, modes for which the package/shipments approved and the edition of Safety Series No. 6 on which the approval has been based. The technical information on package mass, authorized contents, and detailed and general description of the package are contained in Table 5. Table 6 shows the certificates reported to the IAEA Secretariat by each participating Member State

  1. Chemistry: A contemporary approach. Second edition

    International Nuclear Information System (INIS)

    Miller, G.T.; Lygre, D.; Smith, W.

    1987-01-01

    This text provides a basic introduction to the principles of chemistry (in Chapters 1-9) and to the three major applied areas: Resources and Environment (four chapters); consumer issues (five chapters); and health (four chapters). The broad coverage of applications appeals to widely varied interests and provides variety for assignments. Following changes are made in the new edition: Completely rewritten to simplify the overall structure and presentation. Core section now includes chapters on acid/base and oxidation/reduction reactions, biochemistry, and a section on stoichiometry. Environmental section updated. New chapter on metal and mineral resources. Consumer chemistry expanded considerably. Health section expanded to include new material on genetic engineering, prosthetic engineering, and new drugs

  2. Methods and apparatus for graphical display and editing of flight plans

    Science.gov (United States)

    Gibbs, Michael J. (Inventor); Adams, Jr., Mike B. (Inventor); Chase, Karl L. (Inventor); Lewis, Daniel E. (Inventor); McCrobie, Daniel E. (Inventor); Omen, Debi Van (Inventor)

    2002-01-01

    Systems and methods are provided for an integrated graphical user interface which facilitates the display and editing of aircraft flight-plan data. A user (e.g., a pilot) located within the aircraft provides input to a processor through a cursor control device and receives visual feedback via a display produced by a monitor. The display includes various graphical elements associated with the lateral position, vertical position, flight-plan and/or other indicia of the aircraft's operational state as determined from avionics data and/or various data sources. Through use of the cursor control device, the user may modify the flight-plan and/or other such indicia graphically in accordance with feedback provided by the display. In one embodiment, the display includes a lateral view, a vertical profile view, and a hot-map view configured to simplify the display and editing of the aircraft's flight-plan data.

  3. Radiation protection and safety of radiation sources international basic safety standards

    CERN Document Server

    International Atomic Energy Agency. Vienna

    2014-01-01

    The Board of Governors of the IAEA first approved Basic Safety Standards in June 1962; they were published by the IAEA as IAEA Safety Series No. 9. A revised edition was issued in 1967. A third revision was published by the IAEA as the 1982 Edition of IAEA Safety Series No. 9 ; this edition was jointly sponsored by the IAEA, ILO, OECD/NEA and the WHO. The next edition was International Basic Safety Standards for Protection against Ionizing Radiation and for the Safety of Radiation Sources, published by the IAEA as IAEA Safety Series No. 115 in February 1996, and jointly sponsored by the FAO, IAEA, ILO, OECD/NEA, PAHO and the WHO.

  4. Accelerator-based intense neutron source for materials R and D

    International Nuclear Information System (INIS)

    Jameson, R.A.

    1990-01-01

    Accelerator-based neutron sources for R and D of materials in nuclear energy systems, including fusion reactors, can provide sufficient neutron flux, flux-volume, fluence and other attractive features for many aspects of materials research. The neutron spectrum produced from the D-Li reaction has been judged useful for many basic materials research problems, and satisfactory as an approximation of the fusion process. A most interesting aspect for materials researchers is the increased flexibility and opportunities for experimental configurations that a modern accelerator-based source could add to the set of available tools. First, of course, is a high flux of neutrons. Four other tools are described: 1. The output energy of the deuteron beam can be varied to provide energy selectivity for the materials researcher. The energy would typically be varied in discrete steps; the number of steps can be adjusted depending on actual needs and costs. 2. The materials sample target chamber could be irradiated by more than one beam, from different angles. This would provide many possibilities for tailoring the flux distribution. 3. Advanced techniques in magnetic optics systems allow the density distribution of the deuteron beam at the target to be tailored. Controlled distributions from Gaussian to uniform to hollow can be provided. This affords further control of the distribution in the target chamber. 4. The accelerator and associated beam transport elements are all essentially electronic systems and, therefore, can be controlled and modulated on a time cycle basis. Therefore, all of the above tools could be varied in possibly complex patterns under computer control; this may open further experimental approaches for studying various rate-dependent effects. These considerations will be described in the context of the Energy Selective Neutron Irradiation Test (ESNIT) facility which is conceived at JAERI. (author)

  5. Editing faces in videos

    OpenAIRE

    Amberg, Brian

    2011-01-01

    Editing faces in movies is of interest in the special effects industry. We aim at producing effects such as the addition of accessories interacting correctly with the face or replacing the face of a stuntman with the face of the main actor. The system introduced in this thesis is based on a 3D generative face model. Using a 3D model makes it possible to edit the face in the semantic space of pose, expression, and identity instead of pixel space, and due to its 3D nature allows...

  6. Reexamination of the source material of acid igneous rocks, based on the selected Sr isotopic data

    International Nuclear Information System (INIS)

    Kagami, Hiroo; Shuto, Kenji; Gorai, Masao

    1975-01-01

    The relation between the ages and the initial strontium isotopic compositions obtained from acid igneous rocks by the whole-rock isochron method is re-examined, on the basis of the selected data. The points based on the data having high values of standard deviation (on the isochrons) show considerable scattering. This is probably ascribed to admixture of sialic materials, or secondary alteration and other geologic causes. The points based on the data having lower values of standard deviation (sigma value: 0.0001 - 0.0019), on the other hand, are evidently plotted within a narrow region just above the presumed Sr evolutional region of the source material of oceanic tholeiites. It is noteworthy that the former region meets the latter region at an earlier stage of the evolutional history of the earth (about 40 x 10 8 yrs. ago or older). It may be conceivable that the former region is the Sr evolutional region of the source material of acid igneous rocks. Considering from the inclination of the above Sr evolutional region, the source material of most of acid igneous rocks may possibly be a certain basic material, chemically similar to the continental tholeiitic basalts or basaltic andesites. On the other hand, the source material of a few acid igneous rocks with low initial strontium isotopic ratios may be a certain basic material resembling the oceanic tholeiites. Another possibility is that these acid igneous rocks and oceanic tholeiites may have been formed, under different physical conditions, directly from a certain common source material presumably of peridotitic composition. (auth.)

  7. [The research on the edition of Daquanbencao (Complete Collection of Materia Medica)].

    Science.gov (United States)

    Li, Jian; Zhang, Wei; Zhang, Rui-xian

    2009-07-01

    Zhengleibencao (Classified Materia Medica) had been formed into several kinds of edition systems during its dissemination, among which there was the edition system of Daquanbencao (Complete Collection of Materia Medica). Daquanbencao was originally carved in the Jin dynasty, thereafter it was re-carved in the Yuan, Ming and Qing dynasties so as to form a series of editions such as the edition of Zhenyou in the second year of the Jin dynasty; the edition of the Zongwenshuyuan college in Dade renyan year of the Yuan dynasty; the WANG Qiu's carved edition of Shangyitang hall in the Ming dynasty; the carved edition of Jishanshuyuan, the Jishang mountain college in the Ming dynasty, the reprinted edition of PENG Duan-wu in the Ming dynasty, the supplementary edition of YANG Bi-da in the Qing dynasty;, and the carved edition of KE Feng-shi in the Qing dynasty. Among all the editions, Chongkanjingshizhengleidaquanbencao (Reprinted Classified Daquan Materia Medica from Historical Classics) was the representative one. As a representative of the above editions, the carved edition of WANG took the edition of the Zongwenshuyuan college of the Yuan dynasty as the original edition, but the images picture of materia medica adopted from the edition of Zhenghebencao (Materia Medica of the Zhenghe era).

  8. Fusion Canada issue 32. Final edition

    International Nuclear Information System (INIS)

    1997-07-01

    Fusion Canada is a bulletin of the National Fusion Program, this is the last edition. Included in this July edition are articles on Funding for Canada's fusion program, Research and Development on TdeV-96 , Divertor Maintenance Robotics and reference listing for Canada's Fusion research and development sites

  9. Environmental Radioactivity from Natural, Industrial, and Military Sources

    International Nuclear Information System (INIS)

    Maarouf, B. H.

    2007-01-01

    This book is a translation of the fourth edition of the original book which was written as a reference source for the scientist, engineer, or administrator with a professional interest in the subject, but it may also be a value to the reader who wishes to understand the technical facts behind the public debate. The subject of environmental radioactivity has aspects of vast dimensions. The text of the book concerns primarily with the behavior of radioactive substances when they enter the environment. The important and elaborate technology by which passage of radioactive materials to the environment may be prevented and the equally important field of health physics that is concerned with protecting the atomic energy worker were thus placed beyond the bounds of this work.

  10. Fissile material detection and control facility with pulsed neutron sources and digital data processing

    International Nuclear Information System (INIS)

    Romodanov, V.L.; Chernikova, D.N.; Afanasiev, V.V.

    2010-01-01

    Full text: In connection with possible nuclear terrorism, there is long-felt need of devices for effective control of radioactive and fissile materials in the key points of crossing the state borders (airports, seaports, etc.), as well as various customs check-points. In International Science and Technology Center Projects No. 596 and No. 2978, a new physical method and digital technology have been developed for the detection of fissile and radioactive materials in models of customs facilities with a graphite moderator, pulsed neutron source and digital processing of responses from scintillation PSD detectors. Detectability of fissile materials, even those shielded with various radiation-absorbing screens, has been shown. The use of digital processing of scintillation signals in this facility is a necessary element, as neutrons and photons are discriminated in the time dependence of fissile materials responses at such loads on the electronic channels that standard types of spectrometers are inapplicable. Digital processing of neutron and photon responses practically resolves the problem of dead time and allows implementing devices, in which various energy groups of neutrons exist for some time after a pulse of source neutrons. Thus, it is possible to detect fissile materials deliberately concealed with shields having a large cross-section of absorption of photons and thermal neutrons. Two models of detection and the control of fissile materials were advanced: 1. the model based on graphite neutrons moderator and PSD scintillators with digital technology of neutrons and photons responses separation; 2. the model based on plastic scintillators and detecting of time coincidences of fission particles by digital technology. Facilities that count time coincidences of neutrons and photons occurring in the fission of fissile materials can use an Am Li source of neutrons, e.g. that is the case with the AWCC system. The disadvantages of the facility are related to the issues

  11. Mediated Plastid RNA Editing in Plant Immunity

    Science.gov (United States)

    García-Andrade, Javier; Ramírez, Vicente; López, Ana; Vera, Pablo

    2013-01-01

    Plant regulatory circuits coordinating nuclear and plastid gene expression have evolved in response to external stimuli. RNA editing is one of such control mechanisms. We determined the Arabidopsis nuclear-encoded homeodomain-containing protein OCP3 is incorporated into the chloroplast, and contributes to control over the extent of ndhB transcript editing. ndhB encodes the B subunit of the chloroplast NADH dehydrogenase-like complex (NDH) involved in cyclic electron flow (CEF) around photosystem I. In ocp3 mutant strains, ndhB editing efficiency decays, CEF is impaired and disease resistance to fungal pathogens substantially enhanced, a process recapitulated in plants defective in editing plastid RNAs encoding NDH complex subunits due to mutations in previously described nuclear-encoded pentatricopeptide-related proteins (i.e. CRR21, CRR2). Furthermore, we observed that following a pathogenic challenge, wild type plants respond with editing inhibition of ndhB transcript. In parallel, rapid destabilization of the plastidial NDH complex is also observed in the plant following perception of a pathogenic cue. Therefore, NDH complex activity and plant immunity appear as interlinked processes. PMID:24204264

  12. Sources and Transportation of Bulk, Low-Cost Lunar Simulant Materials

    Science.gov (United States)

    Rickman, D. L.

    2013-01-01

    Marshall Space Flight Center (MSFC) has built the Lunar Surface Testbed using 200 tons of volcanic cinder and ash from the same source used for the simulant series JSC-1. This Technical Memorandum examines the alternatives examined for transportation and source. The cost of low-cost lunar simulant is driven by the cost of transportation, which is controlled by distance and, to a lesser extent, quantity. Metabasalts in the eastern United States were evaluated due to their proximity to MSFC. Volcanic cinder deposits in New Mexico, Colorado, and Arizona were recognized as preferred sources. In addition to having fewer green, secondary minerals, they contain vesicular glass, both of which are desirable. Transportation costs were more than 90% of the total procurement costs for the simulant material.

  13. [Characteristics of acupuncture textbooks on editing mode and content in the Republic of China].

    Science.gov (United States)

    Zhao, Jing; Zhang, Shujian

    2017-09-12

    Sixty-seven textbooks in the Republic of China have been collected and divided into three stages according to their editing modes, named the early stage (1912-1927), the middle stage (1928-1939) and the late stage (1940-1949). The traditional teaching material of acupuncture was predominated at the early stage in the textbook compilation; meanwhile the editing mode was simple, and the content of it focuses on meridians, collaterals and acupoints and the modern scientific theories have been preliminarily introduced. The textbooks at the middle stage were edited as two modes, "western medicine+acupuncture" and "general introduction→meridian points→manipulation (techniques of acupuncture and moxibustion)→treatment". The knowledge in anatomy, physiology and pathology of western medicine has been involved in content, giving the great consideration to the clinical practicability. However, a part of textbooks still followed the traditional theory of acupuncture at the middle stage. At the late stage, the textbooks were edited align with "acupuncture science, moxibustion science, meridian point science and treatment science"; or in supplementation of the "diagnosis" on the base of "general introduction→ meridian points→techniques of acupuncture→treatment", or edited as "general introduction→points→treatment". The compilation of the textbooks at this stage not only followed but also improved the integration of western and Chinese medicine as that at the middle stage, which turned to be more scientific. Additionally, in the teaching content, the acupoint was much more considerable as compared with pulse and the section of diagnosis has been involved. As a result, a framework of acupuncture discipline has been established preliminarily by taking acupuncture technique, moxibustion technique, acupoints and treatment as the core. The development of the editing mode and content of textbooks played a great impact on the unified compilation of the acupuncture

  14. Development of the Macro Command Editing Executive System for Factory Workers-Oriented Programless Visual Inspection System

    Science.gov (United States)

    Anezaki, Takashi; Wakitani, Kouichi; Nakamura, Masatoshi; Kubo, Hiroyasu

    Because visual inspection systems are difficult to tune, they create many problems for the kaizen process. This results in increased development costs and time to assure that the inspection systems function properly. In order to improve inspection system development, we designed an easy-tuning system called a “Program-less” visual inspection system. The ROI macro command which consisted of eight kinds of shape recognition macro commands and decision, operation, control commands was built. Furthermore, the macro command editing executive system was developed by the operation of only the GUI without editing source program. The validity of the ROI macro command was proved by the application of 488 places.

  15. Material sound source localization through headphones

    Science.gov (United States)

    Dunai, Larisa; Peris-Fajarnes, Guillermo; Lengua, Ismael Lengua; Montaña, Ignacio Tortajada

    2012-09-01

    In the present paper a study of sound localization is carried out, considering two different sounds emitted from different hit materials (wood and bongo) as well as a Delta sound. The motivation of this research is to study how humans localize sounds coming from different materials, with the purpose of a future implementation of the acoustic sounds with better localization features in navigation aid systems or training audio-games suited for blind people. Wood and bongo sounds are recorded after hitting two objects made of these materials. Afterwards, they are analysed and processed. On the other hand, the Delta sound (click) is generated by using the Adobe Audition software, considering a frequency of 44.1 kHz. All sounds are analysed and convolved with previously measured non-individual Head-Related Transfer Functions both for an anechoic environment and for an environment with reverberation. The First Choice method is used in this experiment. Subjects are asked to localize the source position of the sound listened through the headphones, by using a graphic user interface. The analyses of the recorded data reveal that no significant differences are obtained either when considering the nature of the sounds (wood, bongo, Delta) or their environmental context (with or without reverberation). The localization accuracies for the anechoic sounds are: wood 90.19%, bongo 92.96% and Delta sound 89.59%, whereas for the sounds with reverberation the results are: wood 90.59%, bongo 92.63% and Delta sound 90.91%. According to these data, we can conclude that even when considering the reverberation effect, the localization accuracy does not significantly increase.

  16. Determination of material and its thickness for Cs-137 gamma source shielding

    International Nuclear Information System (INIS)

    Tukiman

    2008-01-01

    Its has been determined the shielding material and its thickness necessarily conducted due to every material will have different half-thickness characteristics, and by the selection a suitable material and its thickness will be obtained. Half-thickness of any material is the ability of the material at a certain thickness to absorb any radiation intensity so that the intensity becomes half of its source. Sample materials to be used are concrete, wood, and lead with their thickness varied. From experiment data and theoretical computation can be concluded that lead is the suitable material for shielding with the value of HVT for gamma radiation 0,732 cm. For wood and concrete will give half-thickness of 11,0 cm and 3,164 cm respectively. (author)

  17. Boneless Pose Editing and Animation

    DEFF Research Database (Denmark)

    Bærentzen, Jakob Andreas; Hansen, Kristian Evers; Erleben, Kenny

    2007-01-01

    In this paper, we propose a pose editing and animation method for triangulated surfaces based on a user controlled partitioning of the model into deformable parts and rigid parts which are denoted handles. In our pose editing system, the user can sculpt a set of poses simply by transforming...... the handles for each pose. Using Laplacian editing, the deformable parts are deformed to match the handles. In our animation system the user can constrain one or several handles in order to define a new pose. New poses are interpolated from the examples poses, by solving a small non-linear optimization...... problem in order to obtain the interpolation weights. While the system can be used simply for building poses, it is also an animation system. The user can specify a path for a given constraint and the model is animated correspondingly....

  18. Source book of educational materials for radiation therapy. Final report

    International Nuclear Information System (INIS)

    Pijar, M.L.

    1979-08-01

    The Source Book is a listing of educational materials in radiation therapy technology. The first 17 sections correspond to the subjects identified in the ASRT Curriculum Guide for schools of radiation therapy. Each section is divided into publications and in some sections audiovisuals and training aids. Entries are listed without endorsement

  19. Accounting for Independent Schools. Second Edition.

    Science.gov (United States)

    National Association of Independent Schools, Boston, MA.

    This is a thoroughly revised edition of the 1969 publication, "Accounting for Independent Schools," a guide that attempted to codify basic accounting principles and practices for specific application to independent schools. The focus of the second edition is more on refining practices than on initiating them, and more on extending the managerial…

  20. 78 FR 32309 - Distribution of Source Material to Exempt Persons and to General Licensees and Revision of...

    Science.gov (United States)

    2013-05-29

    ... thorium as ``source material'' for atomic weapons and the nuclear fuel cycle. Exemptions from licensing... material in a powdered form, which allows for a greater chance of inhalation or ingestion of the source...

  1. Human germline gene editing: Recommendations of ESHG and ESHRE

    NARCIS (Netherlands)

    de Wert, Guido; Pennings, Guido; Clarke, Angus; Eichenlaub-Ritter, Ursula; van El, Carla G.; Forzano, Francesca; Goddijn, Mariëtte; Heindryckx, Björn; Howard, Heidi C.; Radojkovic, Dragica; Rial-Sebbag, Emmanuelle; Tarlatzis, Basil C.; Cornel, Martina C.

    2018-01-01

    Technological developments in gene editing raise high expectations for clinical applications, first of all for somatic gene editing but in theory also for germline gene editing (GLGE). GLGE is currently not allowed in many countries. This makes clinical applications in these countries impossible

  2. Introduction: Victorian Fiction and the Material Imagination

    Directory of Open Access Journals (Sweden)

    Victoria Mills

    2008-04-01

    Full Text Available How should we deal with the ‘stuff' in books? This is the question addressed in the lead articles of the Spring 2008 issue of 19, all of which focus on some aspect of the material in relation to Victorian fiction. Gas, rocks, jewellery, automata and the entire contents of houses are examined in essays that explore the material imagination of Dickens, Hardy, George Eliot and Thackeray, among others. Moving forward from the previous edition, which different types of collected object, here contributors examine how the material is brought into collision with literature. The phrase 'material imagination' can be traced to the work of Gaston Bachelard who identifies two types of imagination, the formal and the material. Whereas the former focuses on surfaces and the visual perception of images, the latter consists of '…this amazing need for penetration which, going beyond the attractions of the imagination of forms, thinks matter, dreams in it, lives in it, or, in other words, materializes the imaginary'. As Bachelard suggests, the material imagination involves more than just a focus on the representation of objects and the contributions to this edition explore such wide ranging subjects as the gender politics of ownership, dispossession, the body as object, the politics of collecting and display and the dichotomy between the material and immaterial. In addition, this edition features a forum on digitisation and materiality. We are particularly pleased to be able to make use of 19's digital publishing format to further debates about digital media. In the forum, five contributors respond to a series of questions about the nature of the virtual object. All five have worked or are working on nineteenth-century digitisation projects so they are uniquely placed to consider issues surrounding representation and the nature of digital space.

  3. On the source material of magmas - with special reference to Nd isotopic ratios of igneous rocks

    International Nuclear Information System (INIS)

    Shuto, Kenji

    1980-01-01

    In 1973, the Sm-Nd method was first used for the measurement of the absolute age of igneous rocks and meteorites. Subsequently in the following years, the research works by means of the Nd isotopic ratio in igneous rocks have been made strenuously in order to reveal the chemistry of the source materials of magma giving rise to the igneous rocks and further the evolution process of mantle and earth's crust. The fundamental items for the Sm-Nd method are explained. Then, the research results more important in the above connection are given. Finally, the ideas by the author concerning the source materials of magma are presented from the data available on the Nd isotopes in meteorites and igneous rocks. The following matters are described: the fundamentals of Sm-Nd method, the Nd content in seawater, the negative correlation between Nd and Sr isotopic ratios in igneous rocks, magma source materials and Nd isotopes, and considerations on magma source materials. (J.P.N.)

  4. Improvements in algal lipid production: a systems biology and gene editing approach.

    Science.gov (United States)

    Banerjee, Avik; Banerjee, Chiranjib; Negi, Sangeeta; Chang, Jo-Shu; Shukla, Pratyoosh

    2018-05-01

    In the wake of rising energy demands, microalgae have emerged as potential sources of sustainable and renewable carbon-neutral fuels, such as bio-hydrogen and bio-oil. For rational metabolic engineering, the elucidation of metabolic pathways in fine detail and their manipulation according to requirements is the key to exploiting the use of microalgae. Emergence of site-specific nucleases have revolutionized applied research leading to biotechnological gains. Genome engineering as well as modulation of the endogenous genome with high precision using CRISPR systems is being gradually employed in microalgal research. Further, to optimize and produce better algal platforms, use of systems biology network analysis and integration of omics data is required. This review discusses two important approaches: systems biology and gene editing strategies used on microalgal systems with a focus on biofuel production and sustainable solutions. It also emphasizes that the integration of such systems would contribute and compliment applied research on microalgae. Recent advances in microalgae are discussed, including systems biology, gene editing approaches in lipid bio-synthesis, and antenna engineering. Lastly, it has been attempted here to showcase how CRISPR/Cas systems are a better editing tool than existing techniques that can be utilized for gene modulation and engineering during biofuel production.

  5. Does atlas-based autosegmentation of neck levels require subsequent manual contour editing to avoid risk of severe target underdosage? A dosimetric analysis

    International Nuclear Information System (INIS)

    Voet, Peter W.J.; Dirkx, Maarten L.P.; Teguh, David N.; Hoogeman, Mischa S.; Levendag, Peter C.; Heijmen, Ben J.M.

    2011-01-01

    Background and purpose: To investigate the dosimetric impact of not editing auto-contours of the elective neck and organs at risk (OAR), generated with atlas-based autosegmentation (ABAS) (Elekta software) for head and neck cancer patients. Materials and methods: For nine patients ABAS auto-contours and auto-contours edited by two observers were available. Based on the non-edited auto-contours clinically acceptable IMRT plans were constructed (designated 'ABAS plans'). These plans were then evaluated for the two edited structure sets, by quantifying the percentage of the neck-PTV receiving more than 95% of the prescribed dose (V 95 ) and the near-minimum dose (D 99 ) in the neck PTV. Dice coefficients and mean contour distances were calculated to quantify the similarity of ABAS auto-contours with the structure sets edited by observer 1 and observer 2. To study the dosimetric importance of editing OAR auto-contours a new IMRT plan was generated for each patient-observer combination, based on the observer's edited CTV and the non-edited salivary gland auto-contours. For each plan mean doses for the non-edited glands were compared with doses for the same glands edited by the observer. Results: For both observers, edited neck CTVs were larger than ABAS auto-contours (p ≤ 0.04), by a mean of 8.7%. When evaluating ABAS plans on the PTVs of the edited structure sets, V 95 reduced by 7.2% ± 5.4% (1 SD) (p 99 was 14.2 Gy (range 1-54 Gy). Even for Dice coefficients >0.8 and mean contour distances 99 up to 11 Gy were observed. For treatment plans based on observer PTVs and non-edited auto-contoured salivary glands, the mean doses in the edited glands differed by only -0.6 Gy ± 1.0 Gy (p = 0.06). Conclusions: Editing of auto-contoured neck CTVs generated by ABAS is required to avoid large underdosages in target volumes. Often used similarity measures for evaluation of auto-contouring algorithms, such as dice coefficients, do not predict well for expected PTV underdose

  6. The expression of apoB mRNA editing factors is not the sole determinant for the induction of editing in differentiating Caco-2 cells

    International Nuclear Information System (INIS)

    Galloway, Chad A.; Smith, Harold C.

    2010-01-01

    Apolipoprotein B mRNA is edited at cytidine 6666 in the enterocytes lining the small intestine of all mammals; converting a CAA codon to a UAA stop codon. The conversion is ∼80% efficient in this tissue and leads to the expression of the truncated protein, ApoB48, essential for secretion of dietary lipid as chylomicrons. Caco-2 cell raft cultures have been used as an in vitro model for the induction of editing activity during human small intestinal cell differentiation. This induction of apoB mRNA editing has been ascribed to the expression of APOBEC-1. In agreement our data demonstrated differentiation-dependent induction of expression of the editing enzyme APOBEC-1 and in addition we show alternative splicing of the essential auxiliary factor ACF. However, transfection of these editing factors in undifferentiated proliferating Caco-2 cells was not sufficient to induce robust apoB mRNA editing activity. Only differentiation of Caco-2 cells could induce more physiological like levels of apoB mRNA editing. The data suggested that additional regulatory mechanism(s) were induced by differentiation that controlled the functional activity of editing factors.

  7. Canadian Reference Sources 1980--A Selection.

    Science.gov (United States)

    Ryder, Dorothy E.

    1981-01-01

    Provides a bibliography of 52 reference sources and 24 new editions and supplements, excluding annuals. Topics include science and technology, art, history, university courses, regional information, native languages, museums, law, geography, Canadian culture, dissertations, sports, antiques, botany, and a variety of directories. (CHC)

  8. An introduction to the mathematical theory of dynamic materials

    CERN Document Server

    Lurie, Konstantin A

    2017-01-01

    Mathematical treatment to properties of dynamic materials, material substances whose properties are variable in space and time are examined in this book. This new edition emphasizes the differences between material optimization techniques in statics and dynamics. Systems with one spatial coordinate and time are used to illustrate essentials of temporal property change in this setting and prompt forthcoming extensions and technical improvements. Since the release of the first edition, a number of new results have created a more complete picture of unusual effects hidden in spatio-temporal material geometry. This renewed look has revealed a conceptually new mechanism of relaxation of material optimization problems in dynamics, which has led to additional resources for optimization previously concealed in the property layouts. Dynamic materials are studied in this book from the following perspectives: ability to appear in dissimilar implementations, universality as formations that are thermodynamically open, and...

  9. Genome Editing in Sugarcane: Challenges ahead

    Directory of Open Access Journals (Sweden)

    Chakravarthi Mohan

    2016-10-01

    Full Text Available Genome editing opens new and unique opportunities for researchers to enhance crop production. Until 2013, the zinc finger nucleases (ZFNs and transcription activator-like effector nucleases (TALENs were the key tools used for genome editing applications. The advent of RNA-guided engineered nucleases - the type II clustered regularly interspaced short palindromic repeat (CRISPR/Cas9 (CRISPR-associated system from Streptococcus pyogenes holds great potential since it is simple, effective and more versatile than ZFNs and TALENs. CRISPR/Cas9 system has already been successfully employed in several crop plants. Use of these techniques is in its infant stage in sugarcane. Jung and Altpeter (2016 have reported TALEN mediated approach for the first time to reduce lignin content in sugarcane to make it amenable for biofuel production. This is so far the only report describing genome editing in sugarcane. Large genome size, polyploidy, low transformation efficiency, transgene silencing and lack of high throughput screening techniques are certainly great challenges for genome editing in sugarcane which would be discussed in detail in this review.

  10. Edit propagation using geometric relationship functions

    KAUST Repository

    Guerrero, Paul; Jeschke, Stefan; Wimmer, Michael; Wonka, Peter

    2014-01-01

    We propose a method for propagating edit operations in 2D vector graphics, based on geometric relationship functions. These functions quantify the geometric relationship of a point to a polygon, such as the distance to the boundary or the direction to the closest corner vertex. The level sets of the relationship functions describe points with the same relationship to a polygon. For a given query point, we first determine a set of relationships to local features, construct all level sets for these relationships, and accumulate them. The maxima of the resulting distribution are points with similar geometric relationships. We show extensions to handle mirror symmetries, and discuss the use of relationship functions as local coordinate systems. Our method can be applied, for example, to interactive floorplan editing, and it is especially useful for large layouts, where individual edits would be cumbersome. We demonstrate populating 2D layouts with tens to hundreds of objects by propagating relatively few edit operations. © 2014 ACM 0730-0301/2014/03- ART15 $15.00.

  11. Edit propagation using geometric relationship functions

    KAUST Repository

    Guerrero, Paul

    2014-04-15

    We propose a method for propagating edit operations in 2D vector graphics, based on geometric relationship functions. These functions quantify the geometric relationship of a point to a polygon, such as the distance to the boundary or the direction to the closest corner vertex. The level sets of the relationship functions describe points with the same relationship to a polygon. For a given query point, we first determine a set of relationships to local features, construct all level sets for these relationships, and accumulate them. The maxima of the resulting distribution are points with similar geometric relationships. We show extensions to handle mirror symmetries, and discuss the use of relationship functions as local coordinate systems. Our method can be applied, for example, to interactive floorplan editing, and it is especially useful for large layouts, where individual edits would be cumbersome. We demonstrate populating 2D layouts with tens to hundreds of objects by propagating relatively few edit operations. © 2014 ACM 0730-0301/2014/03- ART15 $15.00.

  12. The Elementary School Library Collection: A Guide to Books and Other Media, Phases 1-2-3. 20th Edition.

    Science.gov (United States)

    Homa, Linda L., Ed.; And Others

    This collection development aid lists more than 10,000 titles of children's materials available in a variety of formats (in addition to print materials, the guide also includes sound recordings, video cassettes, microcomputer software programs, CD-ROM products, and videodiscs). This 20th anniversary edition contains several special features,…

  13. Electric power plant international. 1976--1977 edition

    Energy Technology Data Exchange (ETDEWEB)

    1975-01-01

    ''Electric Power Plant International'' is intended to provide a comprehensive commercial and technical information source for use by suppliers, operators, and potential purchasers of power plant, and also by suppliers of materials and services to such organizations. It contains information that will help those considering the purchase of power plant to gain a reasonable understanding of the factors that should be taken into account when making a purchasing decision. Consideration is given to the operation, maintenance, and modification of power systems that will be of relevance to those currently operating plant. The publication is designed to act as an interface between suppliers and users of power plant. As part of this function, reference sections contain listings of all the companies that have been located throughout the world, supplying prime movers, generators, generator sets, and fixed-frequency inverter systems. Details of products currently available from these companies are included wherever possible and this is being continuously up-dated and extended to give increased coverage in future editions. The Electrical Research Association Ltd. does not manufacture or supply power plant (apart from some special-purpose static inverter systems), but would be pleased to receive requirement details from any company wishing to inquire about plant purchase. These will be forwarded to appropriate suppliers throughout the world who will be able to submit tenders for suitable products. Inquiry forms are included in Chapter 6 for this purpose.

  14. IMRT fluence map editing to control hot and cold spots

    International Nuclear Information System (INIS)

    Taylor Cook, J.; Tobler, Matt; Leavitt, Dennis D.; Watson, Gordon

    2005-01-01

    Manually editing intensity-modulated radiation therapy (IMRT) fluence maps effectively controls hot and cold spots that the IMRT optimization cannot control. Many times, re-optimizing does not reduce the hot spots or increase the cold spots. In fact, re-optimizing only places the hot and cold spots in different locations. Fluence-map editing provides manual control of dose delivery and provides the best treatment plan possible. Several IMRT treatments were planned using the Varian Eclipse planning system. We compare the effects on dose distributions between fluence-map editing and re-optimization, discuss techniques for fluence-map editing, and analyze differences between fluence editing on one beam vs. multiple beams. When editing a beam's fluence map, it is essential to choose a beam that least affects dose to the tumor and critical structures. Editing fluence maps gives an advantage in treatment planning and provides controlled delivery of IMRT dose

  15. Karlsruhe nuclide chart - new 9. edition 2015

    Energy Technology Data Exchange (ETDEWEB)

    Soti, Zsolt [European Commission, Joint Research Centre (JRC), Institute for Transuranium Elements (ITU), Postfach 2340, DE-76125 Karlsruhe, (Germany); Magill, Joseph; Pfennig, Gerda; Derher, Raymond [Nucleonica GmbH, c/o European Commission, Postfach 2340, DE-76125 Karlsruhe, (Germany)

    2015-07-01

    Following the success of the 8. Edition of the Karlsruhe Nuclide Chart 2012, a new edition is planned for 2015. Since the 2012 edition, more than 100 nuclides have been discovered and about 1400 nuclides have been updated. In summary, the new 9. edition contains decay and radiation data on approximately 3230 ground state nuclides and 740 isomers from 118 chemical elements. The accompanying booklet provides a detailed explanation of the nuclide box structure used in the Chart. An expanded section contains many additional nuclide decay schemes to aid the user to interpret the highly condensed information in the nuclide boxes. The booklet contains - in addition to the latest values of the physical constants and physical properties - a periodic table of the elements, tables of new and updated nuclides, and a difference chart showing the main changes in the Chart graphically. (authors)

  16. Karlsruhe nuclide chart - new 9. edition 2015

    International Nuclear Information System (INIS)

    Soti, Zsolt; Magill, Joseph; Pfennig, Gerda; Derher, Raymond

    2015-01-01

    Following the success of the 8. Edition of the Karlsruhe Nuclide Chart 2012, a new edition is planned for 2015. Since the 2012 edition, more than 100 nuclides have been discovered and about 1400 nuclides have been updated. In summary, the new 9. edition contains decay and radiation data on approximately 3230 ground state nuclides and 740 isomers from 118 chemical elements. The accompanying booklet provides a detailed explanation of the nuclide box structure used in the Chart. An expanded section contains many additional nuclide decay schemes to aid the user to interpret the highly condensed information in the nuclide boxes. The booklet contains - in addition to the latest values of the physical constants and physical properties - a periodic table of the elements, tables of new and updated nuclides, and a difference chart showing the main changes in the Chart graphically. (authors)

  17. 16th edition IEE wiring regulations design and verification of electrical installations

    CERN Document Server

    Scaddan, Brian

    1995-01-01

    This book builds on the basic knowledge and techniques covered in 16th Edition IEE Wiring Regulations Explained and Illustrated, providing the information and revision materials needed for the City & Guilds 2400 (Design, Erection and Verification ofElectrical Installations) exam. All Qualifying Managers will be required to gain this qualification, and Brian Scaddan's book is the ideal text for all students undertaking C&G 2400 courses.

  18. Effect of Fuel Structure Materials on Radiation Source Term in Reactor Core Meltdown

    International Nuclear Information System (INIS)

    Jeong, Hae Sun; Ha, Kwang Soon

    2014-01-01

    The fission product (Radiation Source) releases from the reactor core into the containment is obligatorily evaluated to guarantee the safety of Nuclear Power Plant (NPP) under the hypothetical accident involving a core meltdown. The initial core inventory is used as a starting point of all radiological consequences and effects on the subsequent results of accident assessment. Hence, a proper evaluation for the inventory can be regarded as one of the most important part over the entire procedure of accident analysis. The inventory of fission products is typically evaluated on the basis of the uranium material (e.g., UO2 and USi2) loaded in nuclear fuel assembly, except for the structure materials such as the end fittings, grids, and some kinds of springs. However, the structure materials are continually activated by the neutrons generated from the nuclear fission, and some nuclides of them (e.g., 14 C and 60 Co) can significantly influence on accident assessment. During the severe core accident, the structure components can be also melted with the melting points of temperature relatively lower than uranium material. A series of the calculation were performed by using ORIGEN-S module in SCALE 6.1 package code system. The total activity in each part of structure materials was specifically analyzed from these calculations. The fission product inventory is generally evaluated based on the uranium materials of fuel only, even though the structure components of the assembly are continually activated by the neutrons generated from the nuclear fission. In this study, the activation calculation of the fuel structure materials was performed for the initial source term assessment in the accident of reactor core meltdown. As a result, the lower end fitting and the upper plenum greatly contribute to the total activity except for the cladding material. The nuclides of 56 Mn, '5 1 Cr, 55 Fe, 58 Co, 54 Mn, and 60 Co are analyzed to mainly effect on the activity. This result

  19. Explanatory Supplement to the Astronomical Almanac, Third Edition

    Science.gov (United States)

    Seidelmann, P. Kenneth; Urban, S. E.

    2010-01-01

    "The Explanatory Supplement to the Astronomical Almanac" (hereafter "The Explanatory Supplement") is a comprehensive reference book on the topic of positional astronomy, covering the theories and algorithms used to produce "The Astronomical Almanac" (AsA), an annual publication produced jointly by the Nautical Almanac Office of the US Naval Observatory (USNO) and Her Majesty's Nautical Almanac Office (HMNAO) of the UK Hydrographic Office. The first edition of The Explanatory Supplement appeared in 1961 and was reprinted with amendments during the 1970s. The second edition was printed in 1992 and reprinted until 2006. Since the second edition, several changes have taken place in positional astronomy regarding reference systems and internationally accepted models, data sets, and computational methods; these have been incorporated into the AsA. Additionally, the data presented in the AsA have been modified over the years, with new tables being added and some being discontinued. Given these changes, a new edition of The Explanatory Supplement is appropriate. The third edition has been in development for the last few years and will be available in 2010. The book is organized similarly to the second (1991) edition, with each chapter written by subject matter experts. Authors from USNO and HMNAO contributed to the majority of the book, but there are authors from Jet Propulsion Laboratory, Technical University of Dresden, National Geospatial-Intelligence Agency, University of Texas Austin, and University of Virginia. This paper will discuss this latest edition of the Explanatory Supplement.

  20. [International Panel on 14 MeV Intense Neutron Source Based on Accelerators for Fusion Materials Study

    International Nuclear Information System (INIS)

    Thoms, K.R.; Wiffen, F.W.

    1991-01-01

    Both travelers were members of a nine-person US delegation that participated in an international workshop on accelerator-based 14 MeV neutron sources for fusion materials research hosted by the University of Tokyo. Presentations made at the workshop reviewed the technology developed by the FMIT Project, advances in accelerator technology, and proposed concepts for neutron sources. One traveler then participated in the initial meeting of the IEA Working Group on High Energy, High Flux Neutron Sources in which efforts were begun to evaluate and compare proposed neutron sources; the Fourth FFTF/MOTA Experimenters' Workshop which covered planning and coordination of the US-Japan collaboration using the FFTF reactor to irradiate fusion reactor materials; and held discussions with several JAERI personnel on the US-Japan collaboration on fusion reactor materials

  1. Annotated Bibliography of Textbooks and Reference Materials in Marine Sciences. Provisional Edition. Intergovernmental Oceanographic Commission, Technical Series.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Intergovernmental Oceanographic Commission.

    Presented is an annotated bibliography based on selected materials from a preliminary survey of existing bibliographies, publishers' listings, and other sources. It is intended to serve educators and researchers, especially those in countries where marine sciences are just developing. One hundred annotated and 450 non-annotated entries are…

  2. CRISPR Genome Editing

    Science.gov (United States)

    A research article about a technique for gene editing known as CRISPR-Cas9. The technique has made it much easier and faster for cancer researchers to study mutations and test new therapeutic targets.

  3. Books authored/co-authored and edited/co-edited by members of staff of the Department of Medieval/Medieval and Renaissance Archaeology, Aarhus University, 1971-2014

    DEFF Research Database (Denmark)

    Roesdahl, Else

    2015-01-01

    Chronologically organized list of books authored/co-authored and edited/co-edited by members of staff of the Department of Medieval and Renaissance Archaeology, Aarhus University, 1971-2014......Chronologically organized list of books authored/co-authored and edited/co-edited by members of staff of the Department of Medieval and Renaissance Archaeology, Aarhus University, 1971-2014...

  4. The physical protection of radiation sources and radioactive materials in Tanzania

    International Nuclear Information System (INIS)

    Sungita, Y.Y.; Massalu, I.

    2002-01-01

    Full text: In recognition of the legal deficiency and the awareness of radiation safety, the parliament of the United Republic of Tanzania enacted the protection from radiation act no. 5 of 1983, which established the national radiation commission (NRC) as a regulatory authority. The main objective of the act was to provide for a legal framework and guidance of the control of the use of radiation sources and radioactive materials with the view to achieve an assurance for acceptance level of radiation protection and safety standard. Due to trade liberalization that is currently experienced in the country, the increase in the number of radiation practices is observed yearly. medical diagnostic x-ray facilities constitute 72 % of all radiation installations in the country. Radioactive materials used in research, teaching and industrial application constitute 24 % and those used in therapy and nuclear medicine is 4 %. About seven radioactive materials incidents occurred in Tanzania during 1996-2000. Among these cases, some were illegal possession and across-boarder trafficking of radioactive materials. Theft and losses radioactive equipments or sources were also experienced. This presentation discusses the experienced incidents of illegal possession, theft and loss of radioactive materials and the lesson learnt from those events in connection with our operational laws. The needs for improvement of the whole system of notification, authorization, registration and licensing to cope up with increase in radiation practices and cross-border illegal trafficking of radioactive materials. The importance of involving immigration officers, police and custom officer with proper training in radiation safety aspect is emphasized. The recommendation are given in an attempt to rescue the situation. (author)

  5. REDEN: Named Entity Linking in Digital Literary Editions Using Linked Data Sets

    Directory of Open Access Journals (Sweden)

    Carmen Brando

    2016-07-01

    Full Text Available This paper proposes a graph-based Named Entity Linking (NEL algorithm named REDEN for the disambiguation of authors’ names in French literary criticism texts and scientific essays from the 19th and early 20th centuries. The algorithm is described and evaluated according to the two phases of NEL as reported in current state of the art, namely, candidate retrieval and candidate selection. REDEN leverages knowledge from different Linked Data sources in order to select candidates for each author mention, subsequently crawls data from other Linked Data sets using equivalence links (e.g., owl:sameAs, and, finally, fuses graphs of homologous individuals into a non-redundant graph well-suited for graph centrality calculation; the resulting graph is used for choosing the best referent. The REDEN algorithm is distributed in open-source and follows current standards in digital editions (TEI and semantic Web (RDF. Its integration into an editorial workflow of digital editions in Digital humanities and cultural heritage projects is entirely plausible. Experiments are conducted along with the corresponding error analysis in order to test our approach and to help us to study the weaknesses and strengths of our algorithm, thereby to further improvements of REDEN.

  6. Bibliography of Fynbos ecology: 2nd edition

    CSIR Research Space (South Africa)

    Manders, PT

    1989-12-01

    Full Text Available The first edition of a bibliography of fynbos ecology was produced in 1981 and comprised 814 references to work completed or commenced prior to the initiation of the Fynbos Biome Project. It is appropriate that this second edition...

  7. A Subdivision-Based Representation for Vector Image Editing.

    Science.gov (United States)

    Liao, Zicheng; Hoppe, Hugues; Forsyth, David; Yu, Yizhou

    2012-11-01

    Vector graphics has been employed in a wide variety of applications due to its scalability and editability. Editability is a high priority for artists and designers who wish to produce vector-based graphical content with user interaction. In this paper, we introduce a new vector image representation based on piecewise smooth subdivision surfaces, which is a simple, unified and flexible framework that supports a variety of operations, including shape editing, color editing, image stylization, and vector image processing. These operations effectively create novel vector graphics by reusing and altering existing image vectorization results. Because image vectorization yields an abstraction of the original raster image, controlling the level of detail of this abstraction is highly desirable. To this end, we design a feature-oriented vector image pyramid that offers multiple levels of abstraction simultaneously. Our new vector image representation can be rasterized efficiently using GPU-accelerated subdivision. Experiments indicate that our vector image representation achieves high visual quality and better supports editing operations than existing representations.

  8. Analysis of ceramic materials for impact members in isotopic heat sources

    International Nuclear Information System (INIS)

    Simonen, F.A.; Duckworth, W.H.

    1976-01-01

    Of the available high strength ceramics, silicon nitride offers the most promise followed by silicon carbide and aluminum oxide, and stress analyses show severe limitations on allowable velocities for impact with granite following reentry for these ceramics. Impact velocities in the 100 to 200 fps regime can be achieved only by the addition of an additional layer to distribute the high contact stress. Besides impact limitations, application of ceramic materials in heat sources would present problems both in terms of weight and fabrication. The required thickness of a ceramic impact member would be comparable to that for a carbon-carbon composite material, but the least dense of the high strength ceramics are 2 to 3 times more dense than the carbon-carbon composites. Fabrication of a ceramic heat source would require a high strength bond between the fuel and the impact member if reasonable impact velocities are to be achieved. Formation of such a bond in ceramic materials is a difficult task under normal circumstances, and would be more difficult under the restrictions imposed on the processing and handling of the 238 PuO 2 fuel. 16 fig

  9. The fabrication of carbon nanotube field-effect transistors with semiconductors as the source and drain contact materials.

    Science.gov (United States)

    Xiao, Z; Camino, F E

    2009-04-01

    Sb(2)Te(3) and Bi(2)Te(2)Se semiconductor materials were used as the source and drain contact materials in the fabrication of carbon nanotube field-effect transistors (CNTFETs). Ultra-purified single-walled carbon nanotubes (SWCNTs) were ultrasonically dispersed in N-methyl pyrrolidone solvent. Dielectrophoresis was used to deposit and align SWCNTs for fabrication of CNTFETs. The Sb(2)Te(3)- and Bi(2)Te(2)Se-based CNTFETs demonstrate p-type metal-oxide-silicon-like I-V curves with high on/off drain-source current ratio at large drain-source voltages and good saturation of drain-source current with increasing drain-source voltage. The fabrication process developed is novel and has general meaning, and could be used for the fabrication of SWCNT-based integrated devices and systems with semiconductor contact materials.

  10. A Guide to the Elements, Rev. Edition (by Albert Stwertka)

    Science.gov (United States)

    Berger, Reviewed By Daniel

    1999-12-01

    This edition is identical in format and content to the 1996 edition, now sold as the "library edition", except that the names and information for elements 104-109 have been updated. My earlier review still applies; a page-by-page comparison found this edition identical to the first except as noted in the previous sentence. The major revision has been in size and price. The 50% price reduction is welcome, but the format was not changed when the size was reduced, and the resulting 9-point font puts readers at risk of eyestrain. I would like to correct one of the criticisms in my earlier review There is excellent discussion of the industrial uses of each element, as well as its most common source minerals. The more economically important elements are given extensive discussions, detailing industrial uses of the element and its compounds. However, biological activity is given spotty coverage. There is no mention - under "iron" or elsewhere - of the central biological role of iron in oxygen transport or of magnesium in photosynthesis. When coverage appears it is not bad: the roles of calcium in vertebrate and invertebrate skeletons, of fluorine in reducing tooth decay by changing hydroxyapatite to fluorapatite, and of cobalt in vitamin B12 are discussed. While information on transuranium elements has been updated, there has been no attempt to correct several minor errors in spelling, placement, or even information. On page 14 the 1s subshell appears as part of the L (n = 2) shell, and upon the electrolysis of molten sodium chloride on page 54, "sodium collects atthe cathode, and chloride [sic] at...the anode." On page 73 the etymology of "potash" is still given as "potassium-rich ash" rather than "ash burned down in pots", though it is obvious that the latter is intended. On page 74, a picture caption claims that black powder ("potassium nitrate, wood charcoal, and sulfur") is used in modern, high-powered rifle cartridges. In spite of the mistakes, which are relatively

  11. The NMR probe of high-Tc materials and correlated electron systems

    CERN Document Server

    Walstedt, Russell E

    2018-01-01

    This new edition updates readers in three areas of NMR studies, namely, recent developments in high-Tc materials, heavy fermion systems and actinide oxides are presented.  The NMR probe has yielded a vast array of data for solid state materials, corresponding to different compounds, ionic sites, and nuclear species, as well as to a wide variety of experimental conditions. The last two parts of the book are completely new in this edition, while the first part has seen major updates. This edition features the latest developments for high-Tc materials, especially the advances in the area of pseudogap studies are reviewed.  An in depth overview of heavy fermion systems is presented in the second part,  notably Kondo lattices, quantum critical points and unconventional superconductivity are areas of intense research recently and are covered extensively. Finally, valuable information from NMR studies with actinide oxides will be provided. Ongoing analysis and discussion of NMR data have resulted in a wealth o...

  12. Human Resources Administration: A School-Based Perspective. Fourth Edition

    Science.gov (United States)

    Smith, Richard

    2009-01-01

    Enhanced and updated, this Fourth Edition of Richard E. Smith's highly successful text examines the growing role of the principal in planning, hiring, staff development, supervision, and other human resource functions. The Fourth Edition includes new sections on ethics, induction, and the role of the mentor teacher. This edition also introduces…

  13. Atomic Energy Control Board vocabulary - preliminary edition

    Energy Technology Data Exchange (ETDEWEB)

    Nolet, D [Public Works and Government Services Canada, Montreal, PQ (Canada). Terminology and Documentation Directorate

    1995-09-01

    This preliminary edition was prepared at the Board`s request to help it establish a standardized terminology. It was produced by scanning the 99 French and English documents listed at the end of this Vocabulary. The documents include legislation concerning atomic energy and the transportation of radioactive materials, as well as the Board`s publications, such as the Consultative Documents, Regulatory Documents and Notices. The terms included from the following areas are: radiation protection, reactor technology, nuclear fuel cycle, radioactive material packaging and transportation, radioactive waste management, uranium mines, and medical and industrial applications of radioelements. Also included are the titles of publications and the names of organizations and units. The vocabulary contains 2,589 concepts, sometimes accompanied by definitions, contexts or usage examples. Where terms have been standardized by the Canadian Committee for the Standardization of Nuclear Terminology, this has been indicated. Where possible, we have verified the terms using the TERMIUM, the Government of Canada Linguistic Data Bank. (author).

  14. Atomic Energy Control Board vocabulary - preliminary edition

    International Nuclear Information System (INIS)

    Nolet, D.

    1995-09-01

    This preliminary edition was prepared at the Board's request to help it establish a standardized terminology. It was produced by scanning the 99 French and English documents listed at the end of this Vocabulary. The documents include legislation concerning atomic energy and the transportation of radioactive materials, as well as the Board's publications, such as the Consultative Documents, Regulatory Documents and Notices. The terms included from the following areas are: radiation protection, reactor technology, nuclear fuel cycle, radioactive material packaging and transportation, radioactive waste management, uranium mines, and medical and industrial applications of radioelements. Also included are the titles of publications and the names of organizations and units. The vocabulary contains 2,589 concepts, sometimes accompanied by definitions, contexts or usage examples. Where terms have been standardized by the Canadian Committee for the Standardization of Nuclear Terminology, this has been indicated. Where possible, we have verified the terms using the TERMIUM, the Government of Canada Linguistic Data Bank. (author)

  15. Sustainable Production of Fine Chemicals and Materials Using Nontoxic Renewable Sources.

    Science.gov (United States)

    Kokel, Anne; Török, Béla

    2018-02-01

    Due to declining hydrocarbon resources and strengthening environmental regulations, significant attention is directed toward sustainable and nontoxic supplies for the development of green technologies in a variety of industries. This account provides an overview on the sources and recent applications of such materials surveying the most common nontoxic and renewable resources that can be obtained from biological sources. Developing a broad array of technologies based on these materials would establish a truly sustainable green chemical industry. The study thematically discusses various compound groups, eg, carbohydrates, proteins, and triglycerides (oils). Since often the monomers or building blocks of these biopolymers are of significant importance and produced in large amounts, the applications of these compounds are also reviewed. © The Author 2017. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  16. Genome Editing: A New Approach to Human Therapeutics.

    Science.gov (United States)

    Porteus, Matthew

    2016-01-01

    The ability to manipulate the genome with precise spatial and nucleotide resolution (genome editing) has been a powerful research tool. In the past decade, the tools and expertise for using genome editing in human somatic cells and pluripotent cells have increased to such an extent that the approach is now being developed widely as a strategy to treat human disease. The fundamental process depends on creating a site-specific DNA double-strand break (DSB) in the genome and then allowing the cell's endogenous DSB repair machinery to fix the break such that precise nucleotide changes are made to the DNA sequence. With the development and discovery of several different nuclease platforms and increasing knowledge of the parameters affecting different genome editing outcomes, genome editing frequencies now reach therapeutic relevance for a wide variety of diseases. Moreover, there is a series of complementary approaches to assessing the safety and toxicity of any genome editing process, irrespective of the underlying nuclease used. Finally, the development of genome editing has raised the issue of whether it should be used to engineer the human germline. Although such an approach could clearly prevent the birth of people with devastating and destructive genetic diseases, questions remain about whether human society is morally responsible enough to use this tool.

  17. Measures against illicit trafficking of nuclear material and radioactive sources in the Republic of Belarus

    International Nuclear Information System (INIS)

    Piotoukh, O.

    2001-01-01

    Full text: The Republic of Belarus strives to take an active part in international cooperation in the field of prevention and interception of illicit uses of nuclear material and radioactive sources through: multilateral international agreements and bilateral interagency treatments; information exchange within the IAEA Illicit Trafficking Database; participation in different international seminars, workshops, conferences including those under the IAEA auspices etc. Belarus is constantly improving regulatory, legal and technical aspects of activities aimed at: accounting, control and ensuring of physical protection of nuclear material and security of radioactive sources; exercising efficient control over their export and import; detecting cases of their illicit uses and illegal cross-border movements and informing of such cases through the IAEA Illicit Trafficking Database; developing and providing training opportunities for personnel. Through Resolution 'On Measures for Physical Protection of Nuclear Materials' issued by the Council of Ministers in 1993, Committee for Supervision of Industrial and Nuclear Safety (PROMATOMNADZOR) was appointed as the authority responsible for ensuring physical protection of nuclear materials and facilities. Through Resolution 'On Measures for Fulfillment of Provisions of the Non-Proliferation Treaty' issued by the Council of Ministers in 1993, Promatomnadzor was designated as the national competent authority responsible for the establishment and maintenance of the State System of Accounting and Control of nuclear material. The system accounts all the nuclear material meeting the criteria defined in the Safeguards Agreement with the IAEA. The system includes two levels: i.e. on-site accounting and control and state accounting and control exercised by Promatomnadzor. Apart from reporting to the Agency, the system also provides for national tasks being accomplished: control over uses of nuclear material, its physical protection, access

  18. Development of a nuclear emergency preparedness support system. MEASURES and its advanced edition

    International Nuclear Information System (INIS)

    Hara, Tomohiro; Nakatsuka, Shigehiro; Watanabe, Osami; Adachi, Takeshi

    2007-01-01

    We have developed a new nuclear emergency preparedness support system for a micro scale area, called the advanced edition of MEASURES. The system simulates atmospheric dispersion of radioactive material quickly and accurately, using an airflow database and a dispersion model. It takes less than 15 minutes for 12-hour simulation, on a personal computer. The user can operate the system by GUI. (author)

  19. Guidelines on radiation protection for work with open radioactive sources

    International Nuclear Information System (INIS)

    1995-01-01

    The Danish National Institute of Radiation Protection (SIS) has published this, fourth edition of guidelines on radiation protection for work with open radiation sources. There are few changes compared to the previous edition, film doses are updated and preparation of the Danish legislation with respect to the 1991 ICRP recommendations (ICRP publication 60) is discussed. In this future recommendation the new dose limits will be proposed and new risk factors enlightened. (EG)

  20. Collection of laws and ordinances concerning regulation of atomic energy, 1991 edition

    International Nuclear Information System (INIS)

    1990-01-01

    This is the collection of the laws and ordinances on the regulation of atomic energy, 1991 edition, published under the supervision of Nuclear Safety Bureau, Science and Technology Agency. First, the abbreviated indication of the laws and ordinances is shown. The contents are those as of September 30, 1990. 12 basic laws and ordinances, 45 laws and ordinances on the regulation of nuclear raw materials, nuclear fuel materials and nuclear reactors, 26 laws and ordinances on the prevention of the radiation injuries due to radioisotopes and others, and 29 related laws and ordinances are collected in this book. (K.I.)

  1. KEGGParser: parsing and editing KEGG pathway maps in Matlab.

    Science.gov (United States)

    Arakelyan, Arsen; Nersisyan, Lilit

    2013-02-15

    KEGG pathway database is a collection of manually drawn pathway maps accompanied with KGML format files intended for use in automatic analysis. KGML files, however, do not contain the required information for complete reproduction of all the events indicated in the static image of a pathway map. Several parsers and editors of KEGG pathways exist for processing KGML files. We introduce KEGGParser-a MATLAB based tool for KEGG pathway parsing, semiautomatic fixing, editing, visualization and analysis in MATLAB environment. It also works with Scilab. The source code is available at http://www.mathworks.com/matlabcentral/fileexchange/37561.

  2. Far infrared supplement: Catalog of infrared observations, second edition

    International Nuclear Information System (INIS)

    Gezari, D.Y.; Schmitz, M.; Mead, J.M.

    1988-08-01

    The Far Infrared Supplement: Catalog of Infrared Observations summarizes all infrared astronomical observations at far infrared wavelengths (5 to 1000 microns) published in the scientific literature from 1965 through 1986. The Supplement list contain 25 percent of the observations in the full Catalog of Infrared Observations (CIO), and essentially eliminates most visible stars from the listings. The Supplement is thus more compact than the main catalog, and is intended for easy reference during astronomical observations. The Far Infrared Supplement (2nd Edition) includes the Index of Infrared Source Positions and the Bibliography of Infrared Astronomy for the subset of far infrared observations listed

  3. Bibliography of integral charged particle nuclear data. Archival edition

    International Nuclear Information System (INIS)

    Burrows, T.W.; Dempsey, P.

    1980-03-01

    This is the fourth annual edition of the National Nuclear Data Center charged-particle bibliography. This edition is cumulative and supersedes the previous editions. The bibliography's primary aims are to satisfy the need for a concise and comprehensive index of integral charged-particle cross section data and to provide an index of charged-particle data compiled in the international exchange format. References in this Part are by target for the various incident charged particles (in order of increasing A). The present publication is an archival volume; future publications will be cumulative supplements to this edition

  4. Genetic Determinants of RNA Editing Levels of ADAR Targets in Drosophila melanogaster.

    Science.gov (United States)

    Kurmangaliyev, Yerbol Z; Ali, Sammi; Nuzhdin, Sergey V

    2015-12-12

    RNA editing usually affects only a fraction of expressed transcripts and there is a vast amount of variation in editing levels of ADAR (adenosine deaminase, RNA-specific) targets. Here we explore natural genetic variation affecting editing levels of particular sites in 81 natural strains of Drosophila melanogaster. The analysis of associations between editing levels and single-nucleotide polymorphisms allows us to map putative cis-regulatory regions affecting editing of 16 A-to-I editing sites (cis-RNA editing quantitative trait loci or cis-edQTLs, P < 10(-8)). The observed changes in editing levels are validated by independent molecular technique. All identified regulatory variants are located in close proximity of modulated editing sites. Moreover, colocalized editing sites are often regulated by same loci. Similar to expression and splicing QTL studies, the characterization of edQTLs will greatly expand our understanding of cis-regulatory evolution of gene expression. Copyright © 2016 Kurmangaliyev et al.

  5. Genetic Determinants of RNA Editing Levels of ADAR Targets in Drosophila melanogaster

    Directory of Open Access Journals (Sweden)

    Yerbol Z. Kurmangaliyev

    2016-02-01

    Full Text Available RNA editing usually affects only a fraction of expressed transcripts and there is a vast amount of variation in editing levels of ADAR (adenosine deaminase, RNA-specific targets. Here we explore natural genetic variation affecting editing levels of particular sites in 81 natural strains of Drosophila melanogaster. The analysis of associations between editing levels and single-nucleotide polymorphisms allows us to map putative cis-regulatory regions affecting editing of 16 A-to-I editing sites (cis-RNA editing quantitative trait loci or cis-edQTLs, P < 10−8. The observed changes in editing levels are validated by independent molecular technique. All identified regulatory variants are located in close proximity of modulated editing sites. Moreover, colocalized editing sites are often regulated by same loci. Similar to expression and splicing QTL studies, the characterization of edQTLs will greatly expand our understanding of cis-regulatory evolution of gene expression.

  6. Editing Bosman's stories | MacKenzie | Current Writing: Text and ...

    African Journals Online (AJOL)

    This article looks back at the editing work that went into the fourteen-volume Anniversary Edition of Herman Charles Bosman (1998–2005) and pays particular attention to the editing of Bosman's stories. It examines some of the problems that were encountered in arriving at 'authoritative' versions of the stories and argues ...

  7. Regulations for the Safe Transport of Radioactive Material. 2012 Edition. Specific Safety Requirements (Arabic Edition)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    . The standards are also applied by regulatory bodies and operators around the world to enhance safety in nuclear power generation and in nuclear applications in medicine, industry, agriculture and research. Safety is not an end in itself but a prerequisite for the purpose of the protection of people in all States and of the environment - now and in the future. The risks associated with ionizing radiation must be assessed and controlled without unduly limiting the contribution of nuclear energy to equitable and sustainable development. Governments, regulatory bodies and operators everywhere must ensure that nuclear material and radiation sources are used beneficially, safely and ethically. The IAEA safety standards are designed to facilitate this, and I encourage all Member States to make use of them.

  8. Regulations for the Safe Transport of Radioactive Material. 2012 Edition. Specific Safety Requirements (Chinese Edition)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-03-01

    . The standards are also applied by regulatory bodies and operators around the world to enhance safety in nuclear power generation and in nuclear applications in medicine, industry, agriculture and research. Safety is not an end in itself but a prerequisite for the purpose of the protection of people in all States and of the environment - now and in the future. The risks associated with ionizing radiation must be assessed and controlled without unduly limiting the contribution of nuclear energy to equitable and sustainable development. Governments, regulatory bodies and operators everywhere must ensure that nuclear material and radiation sources are used beneficially, safely and ethically. The IAEA safety standards are designed to facilitate this, and I encourage all Member States to make use of them.

  9. Regulations for the Safe Transport of Radioactive Material. 2012 Edition. Specific Safety Requirements (French Edition)

    International Nuclear Information System (INIS)

    2013-01-01

    conventions. The standards are also applied by regulatory bodies and operators around the world to enhance safety in nuclear power generation and in nuclear applications in medicine, industry, agriculture and research. Safety is not an end in itself but a prerequisite for the purpose of the protection of people in all States and of the environment - now and in the future. The risks associated with ionizing radiation must be assessed and controlled without unduly limiting the contribution of nuclear energy to equitable and sustainable development. Governments, regulatory bodies and operators everywhere must ensure that nuclear material and radiation sources are used beneficially, safely and ethically. The IAEA safety standards are designed to facilitate this, and I encourage all Member States to make use of them.

  10. Regulations for the Safe Transport of Radioactive Material. 2012 Edition. Specific Safety Requirements (Chinese Edition)

    International Nuclear Information System (INIS)

    2013-01-01

    . The standards are also applied by regulatory bodies and operators around the world to enhance safety in nuclear power generation and in nuclear applications in medicine, industry, agriculture and research. Safety is not an end in itself but a prerequisite for the purpose of the protection of people in all States and of the environment - now and in the future. The risks associated with ionizing radiation must be assessed and controlled without unduly limiting the contribution of nuclear energy to equitable and sustainable development. Governments, regulatory bodies and operators everywhere must ensure that nuclear material and radiation sources are used beneficially, safely and ethically. The IAEA safety standards are designed to facilitate this, and I encourage all Member States to make use of them.

  11. Regulations for the Safe Transport of Radioactive Material. 2012 Edition. Specific Safety Requirements (Arabic Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    . The standards are also applied by regulatory bodies and operators around the world to enhance safety in nuclear power generation and in nuclear applications in medicine, industry, agriculture and research. Safety is not an end in itself but a prerequisite for the purpose of the protection of people in all States and of the environment - now and in the future. The risks associated with ionizing radiation must be assessed and controlled without unduly limiting the contribution of nuclear energy to equitable and sustainable development. Governments, regulatory bodies and operators everywhere must ensure that nuclear material and radiation sources are used beneficially, safely and ethically. The IAEA safety standards are designed to facilitate this, and I encourage all Member States to make use of them.

  12. Deformation and fracture mechanics of engineering materials

    National Research Council Canada - National Science Library

    Hertzberg, Richard W; Vinci, Richard Paul; Hertzberg, Jason L

    2012-01-01

    "Hertzberg's 5th edition of Deformation & Fracture Mechanics of Engineering Materials offers several new features including a greater number and variety of homework problems using more computational software...

  13. RNA Editing During Sexual Development Occurs in Distantly Related Filamentous Ascomycetes.

    Science.gov (United States)

    Teichert, Ines; Dahlmann, Tim A; Kück, Ulrich; Nowrousian, Minou

    2017-04-01

    RNA editing is a post-transcriptional process that modifies RNA molecules leading to transcript sequences that differ from their template DNA. A-to-I editing was found to be widely distributed in nuclear transcripts of metazoa, but was detected in fungi only recently in a study of the filamentous ascomycete Fusarium graminearum that revealed extensive A-to-I editing of mRNAs in sexual structures (fruiting bodies). Here, we searched for putative RNA editing events in RNA-seq data from Sordaria macrospora and Pyronema confluens, two distantly related filamentous ascomycetes, and in data from the Taphrinomycete Schizosaccharomyces pombe. Like F. graminearum, S. macrospora is a member of the Sordariomycetes, whereas P. confluens belongs to the early-diverging group of Pezizomycetes. We found extensive A-to-I editing in RNA-seq data from sexual mycelium from both filamentous ascomycetes, but not in vegetative structures. A-to-I editing was not detected in different stages of meiosis of S. pombe. A comparison of A-to-I editing in S. macrospora with F. graminearum and P. confluens, respectively, revealed little conservation of individual editing sites. An analysis of RNA-seq data from two sterile developmental mutants of S. macrospora showed that A-to-I editing is strongly reduced in these strains. Sequencing of cDNA fragments containing more than one editing site from P. confluens showed that at the beginning of sexual development, transcripts were incompletely edited or unedited, whereas in later stages transcripts were more extensively edited. Taken together, these data suggest that A-to-I RNA editing is an evolutionary conserved feature during fruiting body development in filamentous ascomycetes. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  14. A distant cis acting intronic element induces site-selective RNA editing

    DEFF Research Database (Denmark)

    Daniel, Chammiran; Venø, Morten Trillingsgaard; Ekdahl, Ylva

    2012-01-01

    Transcripts have been found to be site selectively edited from adenosine-to-inosine (A-to-I) in the mammalian brain, mostly in genes involved in neurotransmission. While A-to-I editing occurs at double-stranded structures, other structural requirements are largely unknown. We have investigated...... shown to be important for A-to-I editing. We demonstrate that the element also can induce editing in related but normally not edited RNA sequences. In human, thousands of genes are edited in duplexes formed by inverted repeats in non-coding regions. It is likely that numerous such duplexes can induce...... the requirements for editing at the I/M site in the Gabra-3 transcript of the GABA(A) receptor. We identify an evolutionarily conserved intronic duplex, 150 nt downstream of the exonic hairpin where the I/M site resides, which is required for its editing. This is the first time a distant RNA structure has been...

  15. The agents of natural genome editing.

    Science.gov (United States)

    Witzany, Guenther

    2011-06-01

    The DNA serves as a stable information storage medium and every protein which is needed by the cell is produced from this blueprint via an RNA intermediate code. More recently it was found that an abundance of various RNA elements cooperate in a variety of steps and substeps as regulatory and catalytic units with multiple competencies to act on RNA transcripts. Natural genome editing on one side is the competent agent-driven generation and integration of meaningful DNA nucleotide sequences into pre-existing genomic content arrangements, and the ability to (re-)combine and (re-)regulate them according to context-dependent (i.e. adaptational) purposes of the host organism. Natural genome editing on the other side designates the integration of all RNA activities acting on RNA transcripts without altering DNA-encoded genes. If we take the genetic code seriously as a natural code, there must be agents that are competent to act on this code because no natural code codes itself as no natural language speaks itself. As code editing agents, viral and subviral agents have been suggested because there are several indicators that demonstrate viruses competent in both RNA and DNA natural genome editing.

  16. Language Editing at Astronomy & Astrophysics

    Science.gov (United States)

    Adams, J.

    2011-07-01

    In 2002, the A&A Board of Directors voted that all articles must be written in English and decided to improve the overall quality of the language in the articles with the help of a team of language editors. This article reviews the general advantages of editing the English expression and describes both the aims of this effort and its place in the full publication process. This is followed by the Guide to language editing that has been available on the Journal's website for several years now.

  17. Tailoring of materials by atomic oxygen from ECR plasma source

    International Nuclear Information System (INIS)

    Naddaf, Munzer; Bhoraskar, S.V.

    2002-01-01

    Full text: An intense source of oxygen finds important applications in many areas of science, technology and industry. It has been successfully used for surface activation and cleaning in the electronic, chemical and automotive industries. Atomic oxygen and interaction with materials have also a significant importance in space science and technology. This paper describes the detailed studies related to the surface modification and processing of different materials, which include metals and polymers by atomic oxygen produced in microwave assisted electron cyclotron resonance plasma. The energy distribution of ions was measured as a function of plasma parameters and density measurements were supplemented by catalytic probe using nickel and oxidation of silver surface

  18. Systematic identification of edited microRNAs in the human brain

    Science.gov (United States)

    Alon, Shahar; Mor, Eyal; Vigneault, Francois; Church, George M.; Locatelli, Franco; Galeano, Federica; Gallo, Angela; Shomron, Noam; Eisenberg, Eli

    2012-01-01

    Adenosine-to-inosine (A-to-I) editing modifies RNA transcripts from their genomic blueprint. A prerequisite for this process is a double-stranded RNA (dsRNA) structure. Such dsRNAs are formed as part of the microRNA (miRNA) maturation process, and it is therefore expected that miRNAs are affected by A-to-I editing. Editing of miRNAs has the potential to add another layer of complexity to gene regulation pathways, especially if editing occurs within the miRNA–mRNA recognition site. Thus, it is of interest to study the extent of this phenomenon. Current reports in the literature disagree on its extent; while some reports claim that it may be widespread, others deem the reported events as rare. Utilizing a next-generation sequencing (NGS) approach supplemented by an extensive bioinformatic analysis, we were able to systematically identify A-to-I editing events in mature miRNAs derived from human brain tissues. Our algorithm successfully identified many of the known editing sites in mature miRNAs and revealed 17 novel human sites, 12 of which are in the recognition sites of the miRNAs. We confirmed most of the editing events using in vitro ADAR overexpression assays. The editing efficiency of most sites identified is very low. Similar results are obtained for publicly available data sets of mouse brain-regions tissues. Thus, we find that A-to-I editing does alter several miRNAs, but it is not widespread. PMID:22499667

  19. Non-GMO genetically edited crop plants.

    Science.gov (United States)

    Kanchiswamy, Chidananda Nagamangala; Malnoy, Mickael; Velasco, Riccardo; Kim, Jin-Soo; Viola, Roberto

    2015-09-01

    Direct delivery of purified Cas9 protein with guide RNA into plant cells, as opposed to plasmid-mediated delivery, displays high efficiency and reduced off-target effects. Following regeneration from edited cells, the ensuing plant is also likely to bypass genetically modified organism (GMO) legislation as the genome editing complex is degraded in the recipient cells. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Peer-editing Practice in the Writing Classroom: Benefits and Drawbacks

    Directory of Open Access Journals (Sweden)

    Ann Rosnida Md. Deni

    2011-01-01

    Full Text Available Small scale studies have shown that peer-editing is beneficial to students as it increases their awareness of the complex process of writing, it improves their knowledge of and skills in writing and helps them become more autonomous in learning. Teachers too may benefit from peer-editing as this practice discloses invaluable information on students’ writing weaknesses and strengths: and teachers’ teaching effectiveness. This is a small scale study conducted on fifteen first-year degree students majoring in Tourism to view the usefulness of peer-editing practice in enhancing their writing skills. Retrospective notes were taken to record students’ receptiveness and reaction towards peer editing practice: students writing samples and peer- editing questionnaires were analyzed to view students’ revisions and comments; and an open— ended questionnaire was distributed to identify students perceptions of peer—editing practice in the writing classroom. Analysis of data gathered revealed that peer-editing practice benefitted both the teacher and most of her students as it exposed important information that could improve her teaching of writing and her students’ writing practices. Data analysis also. however, discloses that peer-editing practice may have adverse effects on students’ motivation and improvement in writing if they are not deployed properly.

  1. Thermodynamics of Fluids Under Flow Second Edition

    CERN Document Server

    Jou, David; Criado-Sancho, Manuel

    2011-01-01

    This is the second edition of the book “Thermodynamics of Fluids under Flow,” which was published in 2000 and has now been corrected, expanded and updated. This is a companion book to our other title Extended irreversible thermodynamics (D. Jou, J. Casas-Vázquez and G. Lebon, Springer, 4th edition 2010), and of the textbook Understanding non-equilibrium thermodynamics (G. Lebon, D. Jou and J. Casas-Vázquez, Springer, 2008. The present book is more specialized than its counterpart, as it focuses its attention on the non-equilibrium thermodynamics of flowing fluids, incorporating non-trivial thermodynamic contributions of the flow, going beyond local equilibrium theories, i.e., including the effects of internal variables and of external forcing due to the flow. Whereas the book's first edition was much more focused on polymer solutions, with brief glimpses into ideal and real gases, the present edition covers a much wider variety of systems, such as: diluted and concentrated polymer solutions, polymer ble...

  2. Revised legislation affecting the transport of radioactive materials

    International Nuclear Information System (INIS)

    Rowlands, R.P.

    1976-01-01

    The revised edition of the model Regulations for the safe transport of radioactive materials (1973, Vienna, International Atomic Energy Agency Safety Series no.6) has acted as the basis for the conditions of carriage and regulatory requirements in Great Britain. The changes introduced in this revised edition are discussed, and the current Regulations and Codes of Practice covering U.K. and international transport by road, sea, rail and air reviewed. (U.K.)

  3. Low-reactive circulating fluidized bed combustion (CFBC) fly ashes as source material for geopolymer synthesis

    International Nuclear Information System (INIS)

    Xu Hui; Li Qin; Shen Lifeng; Zhang Mengqun; Zhai Jianping

    2010-01-01

    In this contribution, low-reactive circulating fluidized bed combustion (CFBC) fly ashes (CFAs) have firstly been utilized as a source material for geopolymer synthesis. An alkali fusion process was employed to promote the dissolution of Si and Al species from the CFAs, and thus to enhance the reactivity of the ashes. A high-reactive metakaolin (MK) was also used to consume the excess alkali needed for the fusion. Reactivities of the CFAs and MK were examined by a series of dissolution tests in sodium hydroxide solutions. Geopolymer samples were prepared by alkali activation of the source materials using a sodium silicate solution as the activator. The synthesized products were characterized by mechanical testing, scanning electron microscopy (SEM), X-ray diffractography (XRD), as well as Fourier transform infrared spectroscopy (FTIR). The results of this study indicate that, via enhancing the reactivity by alkali fusion and balancing the Na/Al ratio by additional aluminosilicate source, low-reactive CFAs could also be recycled as an alternative source material for geopolymer production.

  4. Bibliography of integral charged particle nuclear data. Archival edition

    International Nuclear Information System (INIS)

    Burrows, T.W.; Dempsey, P.

    1980-03-01

    This is the fourth annual edition of the National Nuclear Data Center charged-particle bibliography. This edition is cumulative and supersedes the previous editions. The bibliography's primary aims are to satisfy the need for a concise and comprehensive index of integral charged-particle cross section data and to provide an index of charged-particle data compiled in the international exchange format, EXFOR. This part of the publication deals with isotope production; references are ordered by mass of the nuclide produced. The present publication is an archival volume; future publications will be cumulative supplements to this edition

  5. Nanoparticles for Site Specific Genome Editing

    Science.gov (United States)

    McNeer, Nicole Ali

    Triplex-forming peptide nucleic acids (PNAs) can be used to coordinate the recombination of short 50-60 by "donor DNA" fragments into genomic DNA, resulting in site-specific correction of genetic mutations or the introduction of advantageous genetic modifications. Site-specific gene editing in hematopoietic stem and progenitor cells (HSPCs) could result in treatment or cure of inherited disorders of the blood such as beta-thalassemia. Gene editing in HSPCs and differentiated T cells could help combat HIV/AIDs by modifying receptors, such as CCR5, necessary for R5-tropic HIV entry. However, translation of genome modification technologies to clinical practice is limited by challenges in intracellular delivery, especially in difficult-to-transfect hematolymphoid cells. In vivo gene editing could also provide novel treatment for systemic monogenic disorders such as cystic fibrosis, an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane receptor. Here, we have engineered biodegradable nanoparticles to deliver oligonucleotides for site-specific genome editing of disease-relevant genes in human cells, with high efficiency, low toxicity, and editing of clinically relevant cell types. We designed nanoparticles to edit the human beta-globin and CCR5 genes in hematopoietic cells. We show that poly(lactic-co-glycolic acid) (PLGA) nanoparticles can delivery PNA and donor DNA for site-specific gene modification in human hematopoietic cells in vitro and in vivo in NOD-scid IL2rgammanull mice. Nanoparticles delivered by tail vein localized to hematopoietic compartments in the spleen and bone marrow of humanized mice, resulting in modification of the beta-globin and CCR5 genes. Modification frequencies ranged from 0.005 to 20% of cells depending on the organ and cell type, without detectable toxicity. This project developed highly versatile methods for delivery of therapeutics to hematolymphoid cells and hematopoietic stem cells, and will help to

  6. Compilation of air-pollutant emission factors. Volume 1. Stationary point and area sources. Fourth edition. Supplement D

    International Nuclear Information System (INIS)

    Joyner, W.M.

    1991-09-01

    In the Supplement to the Fourth Edition of AP-42, new or revised emissions data are presented for Natural Gas Combustion; Residential Fireplaces, Residential Wood Stoves; Refuse Combustion; Nonindustrial Surface Coating; Waste Water Collection, Treatment and Storage; Polyvinyl Chloride and Polypropylene; Poly(ethylene terephthalate); Polystyrene; Ammonium Phosphates; Portland Cement Manufacturing; Sand and Gravel Processing; Western Surface Coal Mining; Wildfires and Prescribed Burning; Wet Cooling Towers and Industrial Flares

  7. Country Nuclear Power Profiles - 2009 Edition

    International Nuclear Information System (INIS)

    2009-08-01

    The Country Nuclear Power Profiles compiles background information on the status and development of nuclear power programs in Member States. It consists of organizational and industrial aspects of nuclear power programs and provides information about the relevant legislative, regulatory, and international framework in each country. Its descriptive and statistical overview of the overall economic, energy, and electricity situation in each country, and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programs in the world. The preparation of Country Nuclear Power Profiles (CNPP) was initiated in 1990s. It responded to a need for a database and a technical publication containing a description of the energy and economic situation, the energy and the electricity sector, and the primary organizations involved in nuclear power in IAEA Member States. This is the 2009 edition issued on CD-ROM and Web pages. It updates the country information for 44 countries. The CNPP is updated based on information voluntarily provided by participating IAEA Member States. Participants include the 30 countries that have operating nuclear power plants, as well as 14 countries having past or planned nuclear power programmes (Bangladesh, Egypt, Ghana, Indonesia, the Islamic Republic of Iran, Italy, Kazakhstan, Nigeria, Philippines, Poland, Thailand, Tunisia, Turkey and Vietnam). For the 2009 edition, 26 countries provided updated or new profiles. For the other countries, the IAEA updated the profile statistical tables on nuclear power, energy development, and economic indicators based on information from IAEA and World Bank databases

  8. Country Nuclear Power Profiles - 2011 Edition

    International Nuclear Information System (INIS)

    2011-08-01

    The Country Nuclear Power Profiles compiles background information on the status and development of nuclear power programs in Member States. It consists of organizational and industrial aspects of nuclear power programs and provides information about the relevant legislative, regulatory, and international framework in each country. Its descriptive and statistical overview of the overall economic, energy, and electricity situation in each country, and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programs in the world. The preparation of Country Nuclear Power Profiles (CNPP) was initiated in 1990s. It responded to a need for a database and a technical publication containing a description of the energy and economic situation, the energy and the electricity sector, and the primary organizations involved in nuclear power in IAEA Member States. This is the 2011 edition issued on CD-ROM and Web pages. It updates the country information for 50 countries. The CNPP is updated based on information voluntarily provided by participating IAEA Member States. Participants include the 29 countries that have operating nuclear power plants, as well as 21 countries having past or planned nuclear power programmes (Bangladesh, Belarus, Chile, Egypt, Ghana, Indonesia, the Islamic Republic of Iran, Italy, Jordan, Kazakhstan, Kuwait, Lithuania, Morocco, Nigeria, Philippines, Poland, Syrian Arab Republic, Thailand, Tunisia, Turkey and Vietnam). For the 2011 edition, 23 countries provided updated or new profiles. For the other countries, the IAEA updated the profile statistical tables on nuclear power, energy development, and economic indicators based on information from IAEA and World Bank databases.

  9. MT Post-editing: A Text Repair Experience for the Foreign Language Class.

    Directory of Open Access Journals (Sweden)

    Ana Niño

    2007-04-01

    Full Text Available Communication also means having to sort out the problems involved in learning a foreign language, especially with regards to production rather than reception. These learning strategies or skills can also be applied to translation teaching methodology, where students put in practice their risk taking, avoidance, reduction and/ or compensatory strategies in getting the message across. We acknowledge translation as a writing task constrained by the source text. In addition, the translation and the writing cycles have in common a generation stage and a revision stage where grammatical, lexical and stylistic correctness is assessed. Somewhere in the middle between translation and writing skills lies MT (Machine Translation post-editing that involves correcting the raw MT output with the aim of providing a quality text according to the intended purpose. Our research is intended to test the suitability of MT post-editing as an activity to promote error correction and, subsequently, to enhance written production in second and foreign language teaching.

  10. 10 CFR 32.74 - Manufacture and distribution of sources or devices containing byproduct material for medical use.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Manufacture and distribution of sources or devices... SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL Generally Licensed Items § 32.74 Manufacture and distribution of sources or devices containing byproduct material for...

  11. Dana's Minerals and How to Study Them, Fourth Edition

    Science.gov (United States)

    Cribb, Warner

    Anyone who spends time in a geology lab, natural science museum, or rock and mineral shop can see that nature provides us with an incredible variety of minerals. Countless introductory geology students get “turned on” to the science of geology by studying minerals. Despite the development of modern instruments that enable rapid and detailed mineral, chemical, and atomic structural analysis, the study of minerals by hand sample remains one of the most popular and economical pursuits of many professional geologists, students, and amateur mineral enthusiasts.Because individuals with varying backgrounds in physical science collect and study minerals, a considerable need exists for a reference text that can be effectively used by both professionals and amateurs. Edward Salisbury Dana published the first such text, Minerals and How to Study Them, over a century ago. The third and last edition of this book was published in 1948. In the 50 years since, considerable changes have occurred in the understanding of mineral chemistry, crystallography, and microscopy. As a result, Dana's third edition is somewhat out of date, and its presentation of material is somewhat antiquated for modern-day readers.

  12. Safety of radiation sources and security of radioactive materials. Proceedings of an international conference

    International Nuclear Information System (INIS)

    1999-01-01

    This International Conference, hosted by the Government of France and co-sponsored by the European Commission, the International Criminal Police Organization (Interpol) and the World Customs Organization (WCO), was the first one devoted to the safety of radiation sources and the security of radioactive materials and - for the first time - brought together radiation safety experts, regulators, and customs and police officers, who need to closely co-operate for solving the problem of illicit trafficking. The technical sessions reviewed the state of the art of twelve major topics, divided into two groups: the safety of radiation sources and the security of radioactive materials. The safety part comprised regulatory control, safety assessment techniques, engineering and managerial measures, lessons from experience, international cooperation through reporting systems and databases, verification of safety through inspection and the use of performance indicators for a regulatory programme. The security part comprised measures to prevent breaches in the security of radioactive materials, detection and identification techniques for illicit trafficking, response to detected cases and seized radioactive materials, strengthening awareness, training and exchange of information. The Conference was a success in fostering information exchange through the reviews of the state of the art and the frank and open discussions. It raised awareness of the need for Member States to ensure effective systems of control and for preventing, detecting and responding to illicit trafficking in radioactive materials. The Conference finished by recommending investigating whether international undertakings concerned with an effective operation of national systems for ensuring the safety of radiation sources and security of radioactive materials

  13. Introducing ZBrush 3rd Edition

    CERN Document Server

    Keller, Eric

    2012-01-01

    Learn ZBrush inside and out with this updated new edition Get totally comfortable sculpting in a digital environment with the latest edition of this bestselling beginner's guide to ZBrush. Fully updated for the newest version of the software, ZBrush 4R3, this book dispels any fears you might have about the difficulty of using ZBrush and soon has you creating realistic, cartoon, and organic models with flair. Learn all the essentials, as you complete fun tutorials on painting, meshes, organic scripting, hard surface sculpting, lighting, rendering, and more. Introduces you to ZBrush, the sculpt

  14. Medical writing, revising and editing

    DEFF Research Database (Denmark)

    Pilegaard, Morten

    2006-01-01

    The globalization of science makes medical writing, editing and revision a rapidly growing field of linguistic study and practice. Medical science texts are written according to uniform, general guidelines and medical genres have become highly conventionalized in terms of structure and linguistic...... form. Medical editing often takes the form of peer review and mainly addresses issues of contents and overall validity. Medical revision incorporates the checking of the macrostructure and the microstructure of the text, its language and style and its suitability for the target reader or client...

  15. Reading for Understanding: How Reading Apprenticeship Improves Disciplinary Learning in Secondary and College Classrooms. Second Edition

    Science.gov (United States)

    Schoenbach, Ruth; Greenleaf, Cynthia; Murphy, Lynn

    2012-01-01

    Published in partnership with WestEd, this significantly updated second edition of the bestselling book contains strategies for helping students in middle school through community college gain the reading independence to master subject area textbooks and other material. Features of this book include: (1) Based on the Reading Apprenticeship…

  16. Genome editing in pluripotent stem cells: research and therapeutic applications

    Energy Technology Data Exchange (ETDEWEB)

    Deleidi, Michela, E-mail: michela.deleidi@dzne.de [German Center for Neurodegenerative Diseases (DZNE) Tübingen within the Helmholtz Association, Tübingen (Germany); Hertie Institute for Clinical Brain Research, University of Tübingen (Germany); Yu, Cong [Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, New York (United States)

    2016-05-06

    Recent progress in human pluripotent stem cell (hPSC) and genome editing technologies has opened up new avenues for the investigation of human biology in health and disease as well as the development of therapeutic applications. Gene editing approaches with programmable nucleases have been successfully established in hPSCs and applied to study gene function, develop novel animal models and perform genetic and chemical screens. Several studies now show the successful editing of disease-linked alleles in somatic and patient-derived induced pluripotent stem cells (iPSCs) as well as in animal models. Importantly, initial clinical trials have shown the safety of programmable nucleases for ex vivo somatic gene therapy. In this context, the unlimited proliferation potential and the pluripotent properties of iPSCs may offer advantages for gene targeting approaches. However, many technical and safety issues still need to be addressed before genome-edited iPSCs are translated into the clinical setting. Here, we provide an overview of the available genome editing systems and discuss opportunities and perspectives for their application in basic research and clinical practice, with a particular focus on hPSC based research and gene therapy approaches. Finally, we discuss recent research on human germline genome editing and its social and ethical implications. - Highlights: • Programmable nucleases have proven efficient and specific for genome editing in human pluripotent stem cells (hPSCs). • Genome edited hPSCs can be employed to study gene function in health and disease as well as drug and chemical screens. • Genome edited hPSCs hold great promise for ex vivo gene therapy approaches. • Technical and safety issues should be first addressed to advance the clinical use of gene-edited hPSCs.

  17. Genome editing in pluripotent stem cells: research and therapeutic applications

    International Nuclear Information System (INIS)

    Deleidi, Michela; Yu, Cong

    2016-01-01

    Recent progress in human pluripotent stem cell (hPSC) and genome editing technologies has opened up new avenues for the investigation of human biology in health and disease as well as the development of therapeutic applications. Gene editing approaches with programmable nucleases have been successfully established in hPSCs and applied to study gene function, develop novel animal models and perform genetic and chemical screens. Several studies now show the successful editing of disease-linked alleles in somatic and patient-derived induced pluripotent stem cells (iPSCs) as well as in animal models. Importantly, initial clinical trials have shown the safety of programmable nucleases for ex vivo somatic gene therapy. In this context, the unlimited proliferation potential and the pluripotent properties of iPSCs may offer advantages for gene targeting approaches. However, many technical and safety issues still need to be addressed before genome-edited iPSCs are translated into the clinical setting. Here, we provide an overview of the available genome editing systems and discuss opportunities and perspectives for their application in basic research and clinical practice, with a particular focus on hPSC based research and gene therapy approaches. Finally, we discuss recent research on human germline genome editing and its social and ethical implications. - Highlights: • Programmable nucleases have proven efficient and specific for genome editing in human pluripotent stem cells (hPSCs). • Genome edited hPSCs can be employed to study gene function in health and disease as well as drug and chemical screens. • Genome edited hPSCs hold great promise for ex vivo gene therapy approaches. • Technical and safety issues should be first addressed to advance the clinical use of gene-edited hPSCs.

  18. Edit Distance to Monotonicity in Sliding Windows

    DEFF Research Database (Denmark)

    Chan, Ho-Leung; Lam, Tak-Wah; Lee, Lap Kei

    2011-01-01

    Given a stream of items each associated with a numerical value, its edit distance to monotonicity is the minimum number of items to remove so that the remaining items are non-decreasing with respect to the numerical value. The space complexity of estimating the edit distance to monotonicity of a ...

  19. Nuclear electronics laboratory manual 1989 edition

    International Nuclear Information System (INIS)

    1989-10-01

    This manual is a joint product of several electronics experts who have been associated with IAEA activity in this field for many years. It is based on the experience of conducting twenty-three training courses on nuclear electronics. Compared with the first edition, published 1984, this edition contains many new experiments, mainly on the advanced technical level. The total number of experiments and special projects is 58. Tabs and figs

  20. Advanced neutron source materials surveillance program

    International Nuclear Information System (INIS)

    Heavilin, S.M.

    1995-01-01

    The Advanced Neutron Source (ANS) will be composed of several different materials, one of which is 6061-T6 aluminum. Among other components, the reflector vessel and the core pressure boundary tube (CPBT), are to be made of 6061-T6 aluminum. These components will be subjected to high thermal neutron fluences and will require a surveillance program to monitor the strength and fracture toughness of the 6061-T6 aluminum over their lifetimes. The purpose of this paper is to explain the steps that were taken in the summer of 1994 toward developing the surveillance program. The first goal was to decide upon standard specimens to use in the fracture toughness and tensile testing. Second, facilities had to be chosen for specimens representing the CPBT and the reflector vessel base, weld, and heat-affected-zone (HAZ) metals. Third, a timetable had to be defined to determine when to remove the specimens for testing

  1. 2010 survey of energy resources. 22nd edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-11-15

    This, the 22nd edition of the World Energy Council's Survey of Energy Resources (SER), is the latest in a long series of reviews of the status of the world's major energy resources. It covers not only the fossil fuels but also the major types of traditional and novel sources of energy. The Survey is a flagship publication of the World Energy Council (WEC), prepared triennially and timed for release at each World Energy Congress. It is a unique document in that no entity other than the WEC compiles such wideranging information on a regular and consistent basis. This highly regarded publication is an essential tool for governments, industry, investors, NGOs and academia.

  2. 2010 survey of energy resources. 22nd edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-11-15

    This, the 22nd edition of the World Energy Council's Survey of Energy Resources (SER), is the latest in a long series of reviews of the status of the world's major energy resources. It covers not only the fossil fuels but also the major types of traditional and novel sources of energy. The Survey is a flagship publication of the World Energy Council (WEC), prepared triennially and timed for release at each World Energy Congress. It is a unique document in that no entity other than the WEC compiles such wideranging information on a regular and consistent basis. This highly regarded publication is an essential tool for governments, industry, investors, NGOs and academia.

  3. The impact of continuity editing in narrative film on event segmentation.

    Science.gov (United States)

    Magliano, Joseph P; Zacks, Jeffrey M

    2011-01-01

    Filmmakers use continuity editing to engender a sense of situational continuity or discontinuity at editing boundaries. The goal of this study was to assess the impact of continuity editing on how people perceive the structure of events in a narrative film and to identify brain networks that are associated with the processing of different types of continuity editing boundaries. Participants viewed a commercially produced film and segmented it into meaningful events, while brain activity was recorded with functional magnetic resonance imaging (MRI). We identified three degrees of continuity that can occur at editing locations: edits that are continuous in space, time, and action; edits that are discontinuous in space or time but continuous in action; and edits that are discontinuous in action as well as space or time. Discontinuities in action had the biggest impact on behavioral event segmentation, and discontinuities in space and time had minor effects. Edits were associated with large transient increases in early visual areas. Spatial-temporal changes and action changes produced strikingly different patterns of transient change, and they provided evidence that specialized mechanisms in higher order perceptual processing regions are engaged to maintain continuity of action in the face of spatiotemporal discontinuities. These results suggest that commercial film editing is shaped to support the comprehension of meaningful events that bridge breaks in low-level visual continuity, and even breaks in continuity of spatial and temporal location. Copyright © 2011 Cognitive Science Society, Inc.

  4. 2015 Edition Health Information Technology (Health IT) Certification Criteria, 2015 Edition Base Electronic Health Record (EHR) Definition, and ONC Health IT Certification Program Modifications. Final rule.

    Science.gov (United States)

    2015-10-16

    This final rule finalizes a new edition of certification criteria (the 2015 Edition health IT certification criteria or "2015 Edition'') and a new 2015 Edition Base Electronic Health Record (EHR) definition, while also modifying the ONC Health IT Certification Program to make it open and accessible to more types of health IT and health IT that supports various care and practice settings. The 2015 Edition establishes the capabilities and specifies the related standards and implementation specifications that Certified Electronic Health Record Technology (CEHRT) would need to include to, at a minimum, support the achievement of meaningful use by eligible professionals (EPs), eligible hospitals, and critical access hospitals (CAHs) under the Medicare and Medicaid EHR Incentive Programs (EHR Incentive Programs) when such edition is required for use under these programs.

  5. Synchrotron light source data book

    International Nuclear Information System (INIS)

    Murphy, J.

    1989-01-01

    The ''Synchrotron Light Source Data Book'' is as its name implies a collection of data on existing and planned synchrotron light sources. The intention was to provide a compendium of tools for the design of electron storage rings as synchrotron radiation sources. The slant is toward the accelerator physicist as other booklets such as the X-ray Data Booklet, edited by D. Vaughan (LBL PUB-490), address the 'use' of synchrotron radiation. It is hoped that the booklet serves as a pocket sized reference to facilitate back of the envelope type calculations. It contains some useful formulae in 'practical units' and a brief description of many of the existing and planned light source lattices

  6. Regulations for the Safe Transport of Radioactive Materials. 1964 Revised Edition

    International Nuclear Information System (INIS)

    1965-01-01

    organizations concerned that they be taken as a basis for relevant national regulations and be applied to international transport. In September 1964, the General Conference of the Agency unanimously adopted a resolution urging Member States and the organizations concerned to give effect to the Director General's recommendation. The revised regulations for the safe transport of radioactive materials will be kept technically up to date in accordance with the procedure set up by the Agency's Board of Governors, in the light of increased knowledge and of the experience gained by the authorities concerned. They will be complemented from time to time by additional data. Further detailed standards for the packaging and testing of large radioactive sources, established within the framework of the revised regulations, will be published in due course as a result of studies currently being made.

  7. Evolutionary analysis reveals regulatory and functional landscape of coding and non-coding RNA editing.

    Science.gov (United States)

    Zhang, Rui; Deng, Patricia; Jacobson, Dionna; Li, Jin Billy

    2017-02-01

    Adenosine-to-inosine RNA editing diversifies the transcriptome and promotes functional diversity, particularly in the brain. A plethora of editing sites has been recently identified; however, how they are selected and regulated and which are functionally important are largely unknown. Here we show the cis-regulation and stepwise selection of RNA editing during Drosophila evolution and pinpoint a large number of functional editing sites. We found that the establishment of editing and variation in editing levels across Drosophila species are largely explained and predicted by cis-regulatory elements. Furthermore, editing events that arose early in the species tree tend to be more highly edited in clusters and enriched in slowly-evolved neuronal genes, thus suggesting that the main role of RNA editing is for fine-tuning neurological functions. While nonsynonymous editing events have been long recognized as playing a functional role, in addition to nonsynonymous editing sites, a large fraction of 3'UTR editing sites is evolutionarily constrained, highly edited, and thus likely functional. We find that these 3'UTR editing events can alter mRNA stability and affect miRNA binding and thus highlight the functional roles of noncoding RNA editing. Our work, through evolutionary analyses of RNA editing in Drosophila, uncovers novel insights of RNA editing regulation as well as its functions in both coding and non-coding regions.

  8. Introduction to Energy - 2nd Edition

    Science.gov (United States)

    Cassedy, Edward S.; Grossman, Peter Z.

    1998-12-01

    Energy issues such as pollution, resource depletion, global warming, nuclear power and waste are problems that demand timely solutions. This book provides a critical examination of the resources, market forces, and social impacts of modern energy production. The book addresses the dilemmas that have arisen due to society's crucial dependence on energy, particularly fossil fuels, and explores the available alternative energy producing technologies. The second edition has increased emphasis on those issues at the forefront of the current energy debate: energy sustainability, climate change, and the radical restructuring of the power industry due to de-regulation. Assuming no prior technical expertise and avoiding complex mathematical formulation, it is directed at a broad readership. The second edition will follow the first in proving especially useful as a textbook for undergraduate programs in Science, Technology and Society (STS), and as a supplementary text in a variety of courses which touch upon energy studies, including environmental and technology policy, environmental, mineral and business law, energy and resource economics. Fully updated second edition of successful first edition that was adopted on Science, Technology and Society courses Provides a critical examination of all aspects of modern energy production for non-technical readers For a broad readership from a variety of backgrounds

  9. Engineered Viruses as Genome Editing Devices

    Science.gov (United States)

    Chen, Xiaoyu; Gonçalves, Manuel A F V

    2016-01-01

    Genome editing based on sequence-specific designer nucleases, also known as programmable nucleases, seeks to modify in a targeted and precise manner the genetic information content of living cells. Delivering into cells designer nucleases alone or together with donor DNA templates, which serve as surrogate homologous recombination (HR) substrates, can result in gene knockouts or gene knock-ins, respectively. As engineered replication-defective viruses, viral vectors are having an increasingly important role as delivery vehicles for donor DNA templates and designer nucleases, namely, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and clustered, regularly interspaced, short palindromic repeats (CRISPR)-associated Cas9 (CRISPR−Cas9) nucleases, also known as RNA-guided nucleases (RGNs). We review this dual role played by engineered viral particles on genome editing while focusing on their main scaffolds, consisting of lentiviruses, adeno-associated viruses, and adenoviruses. In addition, the coverage of the growing body of research on the repurposing of viral vectors as delivery systems for genome editing tools is complemented with information regarding their main characteristics, pros, and cons. Finally, this information is framed by a concise description of the chief principles, tools, and applications of the genome editing field as a whole. PMID:26336974

  10. Ministerial Decree of 13 November 1964 concerning approval of the model of the register for commercial operations covering source materials, ores and radioactive materials

    International Nuclear Information System (INIS)

    1964-01-01

    This Decree prescribes the procedure to be complied with for entering information in the special register for commercial operations concerning source materials, ores and radioactive materials. (NEA) [fr

  11. Chesneys' radiographic imaging: revised and edited by John Ball and Tony Price. 5. ed.

    International Nuclear Information System (INIS)

    Chesney, D.N.

    1989-01-01

    This book (5th edition) reflects the change in emphasis in radiology from photographic processes towards electronic imaging methods. There is new material on image intensifiers and television imaging, digital imaging and digital subtractions. Analyses of the characteristics of, and defects in, images on radiographs, xeroradiographs and the television on screen are included. Methods, equipment and materials used to record the cathode ray tube image are described and there is new material on the principles of alternative diagnostic imaging techniques such as ultrasound, computed tomography and radionuclide imaging which provide cathode ray tube images. The book is primarily for student radiographers and radiographers studying for postdiplomate qualifications. (author)

  12. Experimental screening of carbon-base materials for impact members in isotopic heat sources

    International Nuclear Information System (INIS)

    Bansal, G.K.; Duckworth, W.H.

    1976-11-01

    Fourteen C/C composites and three reentry-grade bulk graphites were evaluated experimentally to determine their applicability for impact member use in radioisotope heat sources. The composites included the following generic types: (1) 2-D cloth lay-ups; (2) 2-D and 3-D felts; (3) 3-D weaves; (4) 3-D pierced fabrics; (5) 7-D weave; and (6) coarse polar weave. Also included was the 2-D randomly wound, resin-impregnated C/C material presently used as the impact member in the MHW RTG and commonly designated ''GIS'' (an acronym for graphite impact shell). The various materials were evaluated as energy absorbing materials. None of the materials in these tests performed appreciably better than the GIS impact member material now used in the MHW heat source, HITCO Pyro Carb 814. Two cloth lay-up composites, HITCO's Pyro Carb 903 and Carborundum's Carbitex 700, were somewhat superior in performance, while the bulk graphites and felt-base composites ranked least effective as energy absorbers. All experimental data and other factors considered to date suggest that Pyro Carb 903 is the best prospect for a bifunctional heat shield and impact member. Its high density (1.80 g/cm 3 ) indicates potentially good ablation resistance to accompany its indicated good performance as an energy absorber

  13. Safety and security of radiation sources and radioactive materials: A case of Zambia - least developed country

    International Nuclear Information System (INIS)

    Banda, S.C.

    1998-01-01

    In Zambia, which is current (1998) classified as a Least Developed Country has applications of nuclear science and technology that cover the medical, industrial, education and research. However, the application is mainly in medical and industry. Through the responsibility of radiation source is within the mandate of the Radiation Protection Board. The aspects involving security fall on different stake holders some that have no technical knowledge on what radiation is about. The stake holders in this category include customs clearing and forwarding agents, state security/defence agencies and the operators. Such a situation demands a national system that should be instituted to meet the safety and security requirements but takes into account the involvement of the diverse stake holders. In addition such system should avoid unnecessary exposure, ensure safety of radioactive materials and sources, detect illicit trade and maintain integrity of such materials or sources. This paper will provide the status on issue in Zambia and the challenges that exist to ensure further development in application of Nuclear Science and Technology (S and T) in the country takes into account the safety and security requirements that avoid deliberate and accidental loss of radiation sources and radioactive materials. The Government has a responsibility to ensure that effective system is established and operated to protect radiation sources and radioactive materials from theft, sabotage and ensure safety. (author)

  14. REDIdb: an upgraded bioinformatics resource for organellar RNA editing sites.

    Science.gov (United States)

    Picardi, Ernesto; Regina, Teresa M R; Verbitskiy, Daniil; Brennicke, Axel; Quagliariello, Carla

    2011-03-01

    RNA editing is a post-transcriptional molecular process whereby the information in a genetic message is modified from that in the corresponding DNA template by means of nucleotide substitutions, insertions and/or deletions. It occurs mostly in organelles by clade-specific diverse and unrelated biochemical mechanisms. RNA editing events have been annotated in primary databases as GenBank and at more sophisticated level in the specialized databases REDIdb, dbRES and EdRNA. At present, REDIdb is the only freely available database that focuses on the organellar RNA editing process and annotates each editing modification in its biological context. Here we present an updated and upgraded release of REDIdb with a web-interface refurbished with graphical and computational facilities that improve RNA editing investigations. Details of the REDIdb features and novelties are illustrated and compared to other RNA editing databases. REDIdb is freely queried at http://biologia.unical.it/py_script/REDIdb/. Copyright © 2010 Elsevier B.V. and Mitochondria Research Society. All rights reserved.

  15. RNA Editing in Plant Mitochondria

    Science.gov (United States)

    Hiesel, Rudolf; Wissinger, Bernd; Schuster, Wolfgang; Brennicke, Axel

    1989-12-01

    Comparative sequence analysis of genomic and complementary DNA clones from several mitochondrial genes in the higher plant Oenothera revealed nucleotide sequence divergences between the genomic and the messenger RNA-derived sequences. These sequence alterations could be most easily explained by specific post-transcriptional nucleotide modifications. Most of the nucleotide exchanges in coding regions lead to altered codons in the mRNA that specify amino acids better conserved in evolution than those encoded by the genomic DNA. Several instances show that the genomic arginine codon CGG is edited in the mRNA to the tryptophan codon TGG in amino acid positions that are highly conserved as tryptophan in the homologous proteins of other species. This editing suggests that the standard genetic code is used in plant mitochondria and resolves the frequent coincidence of CGG codons and tryptophan in different plant species. The apparently frequent and non-species-specific equivalency of CGG and TGG codons in particular suggests that RNA editing is a common feature of all higher plant mitochondria.

  16. CRISPR-Cas9-Edited Site Sequencing (CRES-Seq): An Efficient and High-Throughput Method for the Selection of CRISPR-Cas9-Edited Clones.

    Science.gov (United States)

    Veeranagouda, Yaligara; Debono-Lagneaux, Delphine; Fournet, Hamida; Thill, Gilbert; Didier, Michel

    2018-01-16

    The emergence of clustered regularly interspaced short palindromic repeats-Cas9 (CRISPR-Cas9) gene editing systems has enabled the creation of specific mutants at low cost, in a short time and with high efficiency, in eukaryotic cells. Since a CRISPR-Cas9 system typically creates an array of mutations in targeted sites, a successful gene editing project requires careful selection of edited clones. This process can be very challenging, especially when working with multiallelic genes and/or polyploid cells (such as cancer and plants cells). Here we described a next-generation sequencing method called CRISPR-Cas9 Edited Site Sequencing (CRES-Seq) for the efficient and high-throughput screening of CRISPR-Cas9-edited clones. CRES-Seq facilitates the precise genotyping up to 96 CRISPR-Cas9-edited sites (CRES) in a single MiniSeq (Illumina) run with an approximate sequencing cost of $6/clone. CRES-Seq is particularly useful when multiple genes are simultaneously targeted by CRISPR-Cas9, and also for screening of clones generated from multiallelic genes/polyploid cells. © 2018 by John Wiley & Sons, Inc. Copyright © 2018 John Wiley & Sons, Inc.

  17. Radioactive waste and recoverable material in France. Summary of the National Inventory 2006

    International Nuclear Information System (INIS)

    2006-01-01

    Thorough knowledge is needed if the various types of radioactive waste are to be managed openly, consistently and in a safe manner. All French radioactive material users have subscribed to this process for many years. Under the terms of the French Act of Parliament of 30 December 1991, the Government commissioned the French National Agency for Radioactive Waste Management (or ANDRA) to carry out a survey of all the radioactive waste present on French Territory. Through its efforts to collect and confirm information from many sources over the years, that is mainly from statements made by waste producers and handlers, ANDRA has built up a database on existing waste and its geographical location. This constantly updated resource has been regularly circulated. At the beginning of the century the Government decided to extend the areas covered by this database, in response to the recommendations made by the National Review Board (CNE) and the Parliamentary Office for Evaluating Scientific and Technology Options (OPECST). This is how the first edition of the National Inventory, published in 2004, came about. The National Inventory of Radioactive Waste and Recoverable Material, presents a full panorama of radioactive waste that it groups into waste families that present homogenous characteristics. It describes the state of the waste that may be conditioned (that is, in its final form) or may not be conditioned (that is, has not been put through sufficient treatments to arrive at its final form) at the end of 2004. Furthermore it presents not only a statistical and geographical summary, but a predictive summary, as it provides waste quantity forecasts for 2010, 2020 and beyond. The Inventory also includes recoverable materials that contain radioactivity. They are always accounted for separately because of their special nature. The data is presented in a synthesis report. This summary is the general public version of the report. The synthesis report offers more in

  18. Radioactive waste and recoverable material in France. Summary of the National Inventory 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    Thorough knowledge is needed if the various types of radioactive waste are to be managed openly, consistently and in a safe manner. All French radioactive material users have subscribed to this process for many years. Under the terms of the French Act of Parliament of 30 December 1991, the Government commissioned the French National Agency for Radioactive Waste Management (or ANDRA) to carry out a survey of all the radioactive waste present on French Territory. Through its efforts to collect and confirm information from many sources over the years, that is mainly from statements made by waste producers and handlers, ANDRA has built up a database on existing waste and its geographical location. This constantly updated resource has been regularly circulated. At the beginning of the century the Government decided to extend the areas covered by this database, in response to the recommendations made by the National Review Board (CNE) and the Parliamentary Office for Evaluating Scientific and Technology Options (OPECST). This is how the first edition of the National Inventory, published in 2004, came about. The National Inventory of Radioactive Waste and Recoverable Material, presents a full panorama of radioactive waste that it groups into waste families that present homogenous characteristics. It describes the state of the waste that may be conditioned (that is, in its final form) or may not be conditioned (that is, has not been put through sufficient treatments to arrive at its final form) at the end of 2004. Furthermore it presents not only a statistical and geographical summary, but a predictive summary, as it provides waste quantity forecasts for 2010, 2020 and beyond. The Inventory also includes recoverable materials that contain radioactivity. They are always accounted for separately because of their special nature. The data is presented in a synthesis report. This summary is the general public version of the report. The synthesis report offers more in

  19. Statistical optimisation techniques in fatigue signal editing problem

    International Nuclear Information System (INIS)

    Nopiah, Z. M.; Osman, M. H.; Baharin, N.; Abdullah, S.

    2015-01-01

    Success in fatigue signal editing is determined by the level of length reduction without compromising statistical constraints. A great reduction rate can be achieved by removing small amplitude cycles from the recorded signal. The long recorded signal sometimes renders the cycle-to-cycle editing process daunting. This has encouraged researchers to focus on the segment-based approach. This paper discusses joint application of the Running Damage Extraction (RDE) technique and single constrained Genetic Algorithm (GA) in fatigue signal editing optimisation.. In the first section, the RDE technique is used to restructure and summarise the fatigue strain. This technique combines the overlapping window and fatigue strain-life models. It is designed to identify and isolate the fatigue events that exist in the variable amplitude strain data into different segments whereby the retention of statistical parameters and the vibration energy are considered. In the second section, the fatigue data editing problem is formulated as a constrained single optimisation problem that can be solved using GA method. The GA produces the shortest edited fatigue signal by selecting appropriate segments from a pool of labelling segments. Challenges arise due to constraints on the segment selection by deviation level over three signal properties, namely cumulative fatigue damage, root mean square and kurtosis values. Experimental results over several case studies show that the idea of solving fatigue signal editing within a framework of optimisation is effective and automatic, and that the GA is robust for constrained segment selection

  20. Statistical optimisation techniques in fatigue signal editing problem

    Energy Technology Data Exchange (ETDEWEB)

    Nopiah, Z. M.; Osman, M. H. [Fundamental Engineering Studies Unit Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM (Malaysia); Baharin, N.; Abdullah, S. [Department of Mechanical and Materials Engineering Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 UKM (Malaysia)

    2015-02-03

    Success in fatigue signal editing is determined by the level of length reduction without compromising statistical constraints. A great reduction rate can be achieved by removing small amplitude cycles from the recorded signal. The long recorded signal sometimes renders the cycle-to-cycle editing process daunting. This has encouraged researchers to focus on the segment-based approach. This paper discusses joint application of the Running Damage Extraction (RDE) technique and single constrained Genetic Algorithm (GA) in fatigue signal editing optimisation.. In the first section, the RDE technique is used to restructure and summarise the fatigue strain. This technique combines the overlapping window and fatigue strain-life models. It is designed to identify and isolate the fatigue events that exist in the variable amplitude strain data into different segments whereby the retention of statistical parameters and the vibration energy are considered. In the second section, the fatigue data editing problem is formulated as a constrained single optimisation problem that can be solved using GA method. The GA produces the shortest edited fatigue signal by selecting appropriate segments from a pool of labelling segments. Challenges arise due to constraints on the segment selection by deviation level over three signal properties, namely cumulative fatigue damage, root mean square and kurtosis values. Experimental results over several case studies show that the idea of solving fatigue signal editing within a framework of optimisation is effective and automatic, and that the GA is robust for constrained segment selection.

  1. Algebra Sets, Symbols, and the Language of Thought (Revised Edition)

    CERN Document Server

    Tabak, John

    2011-01-01

    Algebra, Revised Edition describes the history of both strands of algebraic thought. This updated resource describes some of the earliest progress in algebra as well as some of the mathematicians in Mesopotamia, Egypt, China, and Greece who contributed to this early period. It goes on to explore the many breakthroughs in algebraic techniques as well as how letters were used to represent numbers. New material has been added to the chapter on "modern" algebra, a type of mathematical research that continues to occupy the attention of many mathematicians today.

  2. Human BLCAP transcript: new editing events in normal and cancerous tissues.

    Science.gov (United States)

    Galeano, Federica; Leroy, Anne; Rossetti, Claudia; Gromova, Irina; Gautier, Philippe; Keegan, Liam P; Massimi, Luca; Di Rocco, Concezio; O'Connell, Mary A; Gallo, Angela

    2010-07-01

    Bladder cancer-associated protein (BLCAP) is a highly conserved protein among species, and it is considered a novel candidate tumor suppressor gene originally identified from human bladder carcinoma. However, little is known about the regulation or the function of this protein. Here, we show that the human BLCAP transcript undergoes multiple A-to-I editing events. Some of the new editing events alter the highly conserved amino terminus of the protein creating alternative protein isoforms by changing the genetically coded amino acids. We found that both ADAR1 and ADAR2-editing enzymes cooperate to edit this transcript and that different tissues displayed distinctive ratios of edited and unedited BLCAP transcripts. Moreover, we observed a general decrease in BLCAP-editing level in astrocytomas, bladder cancer and colorectal cancer when compared with the related normal tissues. The newly identified editing events, found to be downregulated in cancers, could be useful for future studies as a diagnostic tool to distinguish malignancies or epigenetic changes in different tumors.

  3. Efficient Communication Protocols for Deciding Edit Distance

    DEFF Research Database (Denmark)

    Jowhari, Hossein

    2012-01-01

    In this paper we present two communication protocols on computing edit distance. In our first result, we give a one-way protocol for the following Document Exchange problem. Namely given x ∈ Σn to Alice and y ∈ Σn to Bob and integer k to both, Alice sends a message to Bob so that he learns x...... or truthfully reports that the edit distance between x and y is greater than k. For this problem, we give a randomized protocol in which Alice transmits at most O ˜ (klog 2 n) bits and each party’s time complexity is O ˜ (nlogn+k 2 log 2 n) . Our second result is a simultaneous protocol for edit distance over...... permutations. Here Alice and Bob both send a message to a third party (the referee) who does not have access to the input strings. Given the messages, the referee decides if the edit distance between x and y is at most k or not. For this problem we give a protocol in which Alice and Bob run a O...

  4. Material-specific Conversion Factors for Different Solid Phantoms Used in the Dosimetry of Different Brachytherapy Sources

    Directory of Open Access Journals (Sweden)

    Sedigheh Sina

    2015-07-01

    Full Text Available Introduction Based on Task Group No. 43 (TG-43U1 recommendations, water phantom is proposed as a reference phantom for the dosimetry of brachytherapy sources. The experimental determination of TG-43 parameters is usually performed in water-equivalent solid phantoms. The purpose of this study was to determine the conversion factors for equalizing solid phantoms to water. Materials and Methods TG-43 parameters of low- and high-energy brachytherapy sources (i.e., Pd-103, I-125 and Cs-137 were obtained in different phantoms, using Monte Carlo simulations. The brachytherapy sources were simulated at the center of different phantoms including water, solid water, poly(methyl methacrylate, polystyrene and polyethylene. Dosimetric parameters such as dose rate constant, radial dose function and anisotropy function of each source were compared in different phantoms. Then, conversion factors were obtained to make phantom parameters equivalent to those of water. Results Polynomial coefficients of conversion factors were obtained for all sources to quantitatively compare g(r values in different phantom materials and the radial dose function in water. Conclusion Polynomial coefficients of conversion factors were obtained for all sources to quantitatively compare g(r values in different phantom materials and the radial dose function in water.

  5. Source Correlated Prompt Neutron Activation Analysis for Material Identification and Localization

    Science.gov (United States)

    Canion, Bonnie; McConchie, Seth; Landsberger, Sheldon

    2017-07-01

    This paper investigates the energy spectrum of photon signatures from an associated particle imaging deuterium tritium (API-DT) neutron generator interrogating shielded uranium. The goal is to investigate if signatures within the energy spectrum could be used to indirectly characterize shielded uranium when the neutron signature is attenuated. By utilizing the correlated neutron cone associated with each pixel of the API-DT neutron generator, certain materials can be identified and located via source correlated spectrometry of prompt neutron activation gamma rays. An investigation is done to determine if fission neutrons induce a significant enough signature within the prompt neutron-induced gamma-ray energy spectrum in shielding material to be useful for indirect nuclear material characterization. The signature deriving from the induced fission neutrons interacting with the shielding material was slightly elevated in polyethylene-shielding depleted uranium (DU), but was more evident in some characteristic peaks from the aluminum shielding surrounding DU.

  6. Genome Editing Redefines Precision Medicine in the Cardiovascular Field

    Directory of Open Access Journals (Sweden)

    Elda Dzilic

    2018-01-01

    Full Text Available Genome editing is a powerful tool to study the function of specific genes and proteins important for development or disease. Recent technologies, especially CRISPR/Cas9 which is characterized by convenient handling and high precision, revolutionized the field of genome editing. Such tools have enormous potential for basic science as well as for regenerative medicine. Nevertheless, there are still several hurdles that have to be overcome, but patient-tailored therapies, termed precision medicine, seem to be within reach. In this review, we focus on the achievements and limitations of genome editing in the cardiovascular field. We explore different areas of cardiac research and highlight the most important developments: (1 the potential of genome editing in human pluripotent stem cells in basic research for disease modelling, drug screening, or reprogramming approaches and (2 the potential and remaining challenges of genome editing for regenerative therapies. Finally, we discuss social and ethical implications of these new technologies.

  7. An analysis of teacher’s preparation in implementing 2013 revision edition curriculum on mathematics specialization learning

    Science.gov (United States)

    Susilo, T.; Suryawan, A.

    2018-05-01

    This study aimed to determine the pedagogical competence of teachers, the readiness of planning and implementation of learning related to the implementation 2013 revised edition curriculum on mathematics specialization learning for senior high schools Wonogiri. Informants in this study there are 6 high school mathematics teachers X and XI class who teach in the school district Wonogiri. Data were collected using questionnaire method, interview, observation and documentation. Qualitative data analysis is done interactively through 4 paths: data collection, data reduction, data display, drawing conclusion. The results showed that high school mathematics teacher class X and XI in school district of Wonogiri City. The results show that most high school mathematics teachers in grade X and XI are ready to implement the 2013 revised edition curriculum and a few have not been able to implement due to internal or external factors. High school math teachers at Wonogiri district who are ready to face the 2013 revised edition curriculum have applied 10 teacher pedagogic competency indicators according to Regulation of the national education ministry Number 16 Year 2007 in learning. The readiness and implementation of mathematics learning is in line with the demands of the 2013 revised edition curriculum. Based on the teachers who are not ready, data on issues that arise in the implementation of the 2013 revised edition curriculum. Especially the problems in learning, namely mismatch of Core Competence (KI) and Basic Competence (KD) in teacher manual, material disregard in student handbook and lack of examples of problems that exist in teacher manual.

  8. Materials science issues of plasma source ion implantation

    International Nuclear Information System (INIS)

    Nastasi, M.; Faehl, R.J.; Elmoursi, A.A.

    1996-01-01

    Ion beam processing, including ion implantation and ion beam assisted deposition (IBAD), are established surface modification techniques which have been used successfully to synthesize materials for a wide variety of tribological applications. In spite of the flexibility and promise of the technique, ion beam processing has been considered too expensive for mass production applications. However, an emerging technology, Plasma Source Ion Implantation (PSII), has the potential of overcoming these limitations to become an economically viable tool for mass industrial applications. In PSII, targets are placed directly in a plasma and then pulsed-biased to produce a non-line-of-sight process for intricate target geometries without complicated fixturing. If the bias is a relatively high negative potential (20--100 kV) ion implantation will result. At lower voltages (50--1,200 V), deposition occurs. Potential applications for PSII are in low-value-added products such as tools used in manufacturing, orthopedic devices, and the production of wear coatings for hard disk media. This paper will focus on the technology and materials science associated with PSII

  9. Laboratory study of the PCB transport from primary sources to building materials

    Science.gov (United States)

    The sorption of airborne polychlorinated biphenyls (PCBs) by twenty building materials and their subsequent re-emission (desorption) from concrete were investigated using two 53-L environmental chambers connected in series with a field-collected caulk in the source chamber servin...

  10. Soil Carbon Sequestration and the Greenhouse Effect (2nd Edition)

    Science.gov (United States)

    This volume is a second edition of the book “Soil Carbon Sequestration and The Greenhouse Effect”. The first edition was published in 2001 as SSSA Special Publ. #57. The present edition is an update of the concepts, processes, properties, practices and the supporting data. All chapters are new co...

  11. Beginning XML, 5th Edition

    CERN Document Server

    Fawcett, Joe; Quin, Liam R E

    2012-01-01

    A complete update covering the many advances to the XML language The XML language has become the standard for writing documents on the Internet and is constantly improving and evolving. This new edition covers all the many new XML-based technologies that have appeared since the previous edition four years ago, providing you with an up-to-date introductory guide and reference. Packed with real-world code examples, best practices, and in-depth coverage of the most important and relevant topics, this authoritative resource explores both the advantages and disadvantages of XML and addresses the mo

  12. Health and safety impacts from discrete sources of naturally-occurring and accelerator-produced radioactive materials (NARM)

    International Nuclear Information System (INIS)

    Nussbaumer, D.; Wiblin, C.; Welch, L.

    1993-02-01

    This report characterizes discrete sources of naturally-occurring and accelerator-produced radioactive material (NARM) and estimates risks posed by the possession, use and disposal of them. A distinction between discrete and diffuse NARM sources is made with discrete sources being high activity, low volume and diffuse sources being low activity, high volume. Two nanocuries per gram is used as a separation guide between high and low activity, although use of this value does not impact the report's conclusions. Most NARM is under regulatory control of States that either license or register users but reporting requirements are not uniform. Use in consumer products has declined with virtually no production today; however, lack of information available concerning radiation exposures resulting form possession of ageing radium sources precludes a quantitative risk assessment in this report. The report identifies the type of information needed to permit such an assessment. Regarding accelerator-produced radioactive material (ARM), use of this material in nuclear medicine programs has recently increased. Available radiation exposure data regarding ARM handling and use indicates that the risk to workers and the public is low at this time

  13. Technical editing of research reports in biomedical journals.

    Science.gov (United States)

    Wager, Elizabeth; Middleton, Philippa

    2008-10-08

    Most journals try to improve their articles by technical editing processes such as proof-reading, editing to conform to 'house styles', grammatical conventions and checking accuracy of cited references. Despite the considerable resources devoted to technical editing, we do not know whether it improves the accessibility of biomedical research findings or the utility of articles. This is an update of a Cochrane methodology review first published in 2003. To assess the effects of technical editing on research reports in peer-reviewed biomedical journals, and to assess the level of accuracy of references to these reports. We searched The Cochrane Library Issue 2, 2007; MEDLINE (last searched July 2006); EMBASE (last searched June 2007) and checked relevant articles for further references. We also searched the Internet and contacted researchers and experts in the field. Prospective or retrospective comparative studies of technical editing processes applied to original research articles in biomedical journals, as well as studies of reference accuracy. Two review authors independently assessed each study against the selection criteria and assessed the methodological quality of each study. One review author extracted the data, and the second review author repeated this. We located 32 studies addressing technical editing and 66 surveys of reference accuracy. Only three of the studies were randomised controlled trials. A 'package' of largely unspecified editorial processes applied between acceptance and publication was associated with improved readability in two studies and improved reporting quality in another two studies, while another study showed mixed results after stricter editorial policies were introduced. More intensive editorial processes were associated with fewer errors in abstracts and references. Providing instructions to authors was associated with improved reporting of ethics requirements in one study and fewer errors in references in two studies, but no

  14. Introduction to nuclear science, second edition

    CERN Document Server

    Bryan, Jeff C.

    2013-01-01

    This book was written to provide students who have limited backgrounds in the physical sciences and math with an accessible textbook on nuclear science. Expanding on the foundation of the bestselling first edition, Introduction to Nuclear Science, Second Edition provides a clear and complete introduction to nuclear chemistry and physics, from basic concepts to nuclear power and medical applications. Incorporating suggestions from professors using this book for their courses, the author has created a new text that is approximately 60 percent larger and more comprehensive and flexible than the first.New to This Edition: Thorough review of nuclear forensics, radiology, gamma cameras, and decay through proton or neutron emission More detailed explanations of the necessary mathematics A chapter on dosimetry of radiation fields Expanded discussion of applications, introduced earlier in the text More in-depth coverage of nuclear reactors, including a new chapter examining more reactor types, their safety systems,...

  15. Electronic processes in non-crystalline materials

    CERN Document Server

    Mott, Nevill Francis

    2012-01-01

    Since the first edition of this highly successful book the field saw many great developments both in experimental and theoretical studies of electrical properties of non-crystalline solids. It became necessary to rewrite nearly the whole book, while the aims of the second edition remained the same: to set out the theoretical concepts, to test them by comparison with experiment for a wide variety of phenomena, and to apply them to non-crystalline materials. Sir Nevill Mott shared the1977 Nobel Prize for Physics, awarded for his research work in this field. The reissue of this book as part of th

  16. Spatio-temporal regulation of ADAR editing during development in porcine neural tissues

    DEFF Research Database (Denmark)

    Venø, Morten Trillingsgaard; Bramsen, Jesper Bertram; Bendixen, Christian

    2012-01-01

    Editing by ADAR enzymes is essential for mammalian life. Still, knowledge of the spatio-temporal editing patterns in mammals is limited. By use of 454 amplicon sequencing we examined the editing status of 12 regionally extracted mRNAs from porcine developing brain encompassing a total of 64...... putative ADAR editing sites. In total 24 brain tissues, dissected from up to five regions from embryonic gestation day 23, 42, 60, 80, 100 and 115, were examined for editing....

  17. Genome editing and assisted reproduction: curing embryos, society or prospective parents?

    Science.gov (United States)

    Cavaliere, Giulia

    2018-06-01

    This paper explores the ethics of introducing genome-editing technologies as a new reproductive option. In particular, it focuses on whether genome editing can be considered a morally valuable alternative to preimplantation genetic diagnosis (PGD). Two arguments against the use of genome editing in reproduction are analysed, namely safety concerns and germline modification. These arguments are then contrasted with arguments in favour of genome editing, in particular with the argument of the child's welfare and the argument of parental reproductive autonomy. In addition to these two arguments, genome editing could be considered as a worthy alternative to PGD as it may not be subjected to some of the moral critiques moved against this technology. Even if these arguments offer sound reasons in favour of introducing genome editing as a new reproductive option, I conclude that these benefits should be balanced against other considerations. More specifically, I maintain that concerns regarding the equality of access to assisted reproduction and the allocation of scarce resources should be addressed prior to the adoption of genome editing as a new reproductive option.

  18. The Aldine Edition of Aristotle's De Sensu

    DEFF Research Database (Denmark)

    Bloch, David Kristian

    2006-01-01

    This small article examines the quality of and the textual foundation for the først printed edition ever of Aristotle's De Sensu et Sensibilibus, that is, Aldus Manutius' (1497).......This small article examines the quality of and the textual foundation for the først printed edition ever of Aristotle's De Sensu et Sensibilibus, that is, Aldus Manutius' (1497)....

  19. Recollection Rejection: How Children Edit Their False Memories.

    Science.gov (United States)

    Brainerd, C. J.; Reyna, V. F.

    2002-01-01

    Presents new measure of children's use of an editing operation that suppresses false memories by accessing verbatim traces of true events. Application of the methodology showed that false-memory editing increased dramatically between early and middle childhood. Measure reacted appropriately to experimental manipulations. Developmental reductions…

  20. The law for the regulations of nuclear source materials, nuclear fuel materials and reactors

    International Nuclear Information System (INIS)

    1978-01-01

    This law has following two purposes. At first, it exercises necessary controls concerning nuclear source material, nuclear fuel material and reactors in order to: (a) limit their uses to those for the peaceful purpose; (b) ensure planned uses of them; and (c) ensure the public safety by preventing accidents from their uses. Necessary controls are to be made concerning the refining, fabricating and reprocessing businesses, as well as the construction and operation of reactors. The second purpose of the law is to exercise necessary controls concerning internationally controlled material in order to execute the treaties and other international agreements on the research, development and use of atomic energy (the first chapter). In the second and following chapters the law prescribes controls for the persons who wish to carry on the refining and fabricating businesses, to construct and operate reactors, and to conduct the reprocessing business, as well as for those who use the internationally controlled material, respectively in separate chapters by the category of those businesses. For example, the controls to the person who wishes to construct and operate reactors are: (a) the permission of the business after the examination; (b) the examination and approval of the design and methods of construction prior to the construction; (c) the inspection of the facilities prior to their use; (d) periodic inspections of the facilities; (e) the establishment of requirements for safety measures and punishments to their violations. (Matsushima, A.)

  1. A to I editing in disease is not fake news.

    Science.gov (United States)

    Bajad, Prajakta; Jantsch, Michael F; Keegan, Liam; O'Connell, Mary

    2017-09-02

    Adenosine deaminases acting on RNA (ADARs) are zinc-containing enzymes that deaminate adenosine bases to inosines within dsRNA regions in transcripts. In short, structured dsRNA hairpins individual adenosine bases may be targeted specifically and edited with up to one hundred percent efficiency, leading to the production of alternative protein variants. However, the majority of editing events occur within longer stretches of dsRNA formed by pairing of repetitive sequences. Here, many different adenosine bases are potential targets but editing efficiency is usually much lower. Recent work shows that ADAR-mediated RNA editing is also required to prevent aberrant activation of antiviral innate immune sensors that detect viral dsRNA in the cytoplasm. Missense mutations in the ADAR1 RNA editing enzyme cause a fatal auto-inflammatory disease, Aicardi-Goutières syndrome (AGS) in affected children. In addition RNA editing by ADARs has been observed to increase in many cancers and also can contribute to vascular disease. Thus the role of RNA editing in the progression of various diseases can no longer be ignored. The ability of ADARs to alter the sequence of RNAs has also been used to artificially target model RNAs in vitro and in cells for RNA editing. Potentially this approach may be used to repair genetic defects and to alter genetic information at the RNA level. In this review we focus on the role of ADARs in disease development and progression and on their potential use to artificially modify RNAs in a targeted manner.

  2. Monte Carlo modeling of 60 Co HDR brachytherapy source in water and in different solid water phantom materials

    Directory of Open Access Journals (Sweden)

    Sahoo S

    2010-01-01

    Full Text Available The reference medium for brachytherapy dose measurements is water. Accuracy of dose measurements of brachytherapy sources is critically dependent on precise measurement of the source-detector distance. A solid phantom can be precisely machined and hence source-detector distances can be accurately determined. In the present study, four different solid phantom materials such as polymethylmethacrylate (PMMA, polystyrene, Solid Water, and RW1 are modeled using the Monte Carlo methods to investigate the influence of phantom material on dose rate distributions of the new model of BEBIG 60 Co brachytherapy source. The calculated dose rate constant is 1.086 ± 0.06% cGy h−1 U−1 for water, PMMA, polystyrene, Solid Water, and RW1. The investigation suggests that the phantom materials RW1 and Solid Water represent water-equivalent up to 20 cm from the source. PMMA and polystyrene are water-equivalent up to 10 cm and 15 cm from the source, respectively, as the differences in the dose data obtained in these phantom materials are not significantly different from the corresponding data obtained in liquid water phantom. At a radial distance of 20 cm from the source, polystyrene overestimates the dose by 3% and PMMA underestimates it by about 8% when compared to the corresponding data obtained in water phantom.

  3. Physico-chemical characterisation of material fractions in residual and source-segregated household waste in Denmark

    DEFF Research Database (Denmark)

    Götze, Ramona; Pivnenko, Kostyantyn; Boldrin, Alessio

    2016-01-01

    differences in the physico-chemical properties of residual and source-segregated waste fractions were found for many parameters related to organic matter, but also for elements of environmental concern. Considerable differences in potentially toxic metal concentrations between the individual recyclable......Physico-chemical waste composition data are paramount for the assessment and planning of waste management systems. However, the applicability of data is limited by the regional, temporal and technical scope of waste characterisation studies. As Danish and European legislation aims for higher...... recycling rates evaluation of source-segregation and recycling chains gain importance. This paper provides a consistent up-to-date dataset for 74 physico-chemical parameters in 49 material fractions from residual and 24 material fractions from source-segregated Danish household waste. Significant...

  4. Gene-Editing: Interpretation of Current Law and Legal Policy.

    Science.gov (United States)

    Kim, Na-Kyoung

    2017-09-01

    With the development of the third-generation gene scissors, CRISPR-Cas9, concerns are being raised about ethical and social repercussions of the new gene-editing technology. In this situation, this article explores the legislation and interpretation of the positive laws in South Korea. The BioAct does not specify and regulate 'gene editing' itself. However, assuming that genetic editing is used in the process of research and treatment, we can look to the specific details of the regulations for research on humans as well as gene therapy research in order to see how genetic editing is regulated under the BioAct. BioAct differentiates the regulation between (born) humans and embryos etc. and the regulation differ entirely in the manner and scope. Moreover, due to the fact that gene therapy products are regarded as drugs, they fall under different regulations. The Korean Pharmacopoeia Act put stringent sanctions on clinical trials for gene therapy products and the official Notification "Approval and Examination Regulations for Biological Products, etc." by Food and Drug Safety Administration may be applied to gene editing for gene therapy purposes.

  5. Production of Purified CasRNPs for Efficacious Genome Editing.

    Science.gov (United States)

    Lingeman, Emily; Jeans, Chris; Corn, Jacob E

    2017-10-02

    CRISPR-Cas systems have been harnessed as modular genome editing reagents for functional genomics and show promise to cure genetic diseases. Directed by a guide RNA, a Cas effector introduces a double stranded break in DNA and host cell DNA repair leads to the introduction of errors (e.g., to knockout a gene) or a programmed change. Introduction of a Cas effector and guide RNA as a purified Cas ribonucleoprotein complex (CasRNP) has recently emerged as a powerful approach to alter cell types and organisms. Not only does CasRNP editing exhibit increased efficacy and specificity, it avoids optimization and iteration of species-specific factors such as codon usage, promoters, and terminators. CasRNP editing has been rapidly adopted for research use in many contexts and is quickly becoming a popular method to edit primary cells for therapeutic application. This article describes how to make a Cas9 RNP and outlines its use for gene editing in human cells. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  6. Safety, Security, and Policy Considerations for Plant Genome Editing.

    Science.gov (United States)

    Wolt, Jeffrey D

    2017-01-01

    Genome editing with engineered nucleases (GEEN) is increasingly used as a tool for gene discovery and trait development in crops through generation of targeted changes in endogenous genes. The development of the CRISPR-Cas9 system (clustered regularly interspaced short palindromic repeats with associated Cas9 protein), in particular, has enabled widespread use of genome editing. Research to date has not comprehensively addressed genome-editing specificity and off-target mismatches that may result in unintended changes within plant genomes or the potential for gene drive initiation. Governance and regulatory considerations for bioengineered crops derived from using GEEN will require greater clarity as to target specificity, the potential for mismatched edits, unanticipated downstream effects of off-target mutations, and assurance that genome reagents do not occur in finished products. Since governance and regulatory decision making involves robust standards of evidence extending from the laboratory to the postcommercial marketplace, developers of genome-edited crops must anticipate significant engagement and investment to address questions of regulators and civil society. © 2017 Elsevier Inc. All rights reserved.

  7. The Art of Electronics - 2nd Edition

    Science.gov (United States)

    Horowitz, Paul; Hill, Winfield

    1989-09-01

    This is the thoroughly revised and updated second edition of the hugely successful The Art of Electronics. Widely accepted as the single authoritative text and reference on electronic circuit design, both analog and digital, the original edition sold over 125,000 copies worldwide and was translated into eight languages. The book revolutionized the teaching of electronics by emphasizing the methods actually used by citcuit designers - a combination of some basic laws, rules to thumb, and a large nonmathematical treatment that encourages circuit values and performance. The new Art of Electronics retains the feeling of informality and easy access that helped make the first edition so successful and popular. It is an ideal first textbook on electronics for scientists and engineers and an indispensable reference for anyone, professional or amateur, who works with electronic circuits. The best self-teaching book and reference book in electronics Simply indispensable, packed with essential information for all scientists and engineers who build electronic circuits Totally rewritten chapters on microcomputers and microprocessors The first edition of this book has sold over 100,000 copies in seven years, it has a market in virtually all research centres where electronics is important

  8. Technology Roadmap: Wind Energy. 2013 edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-07-01

    The IEA Wind Power Technology Roadmap 2013 Edition recognises the very significant progress made since the first edition was published in 2009. The technology continues to improve rapidly, and costs of generation from land-based wind installations continue to fall. Wind power is now being deployed in countries with good resources without any dedicated financial incentives. The 2013 Edition targets an increased share (15% to 18%) of global electricity to be provided by wind power in 2050, compared to 12% in the original roadmap of 2009. However, increasing levels of low-cost wind still require predictable, supportive regulatory environments and appropriate market designs. The challenges of integrating higher levels of variable wind power into the grid need to be addressed. For offshore wind, much remains to be done to develop appropriate large-scale systems and to reduce costs. The 2013 Wind Power Roadmap also provides updated analysis on the barriers that exist for the technology and suggests ways to address them, including legal and regulatory recommendations.

  9. De herba lunatica (London, Wellcome Library, 573, f. 149v): edition and translation of a medieval opuscule on the magical properties of common moonwort (Botrychium lunaria Swartz)

    OpenAIRE

    Ferraces Rodríguez, Arsenio

    2014-01-01

    This article provides the first edition of a medieval text on the properties of a plant named herba lunatica. From the description of the plant found in this text as well as in other medieval sources, together with its iconographic representation on the lower margin of the manuscript, we propose its identification with the ‘Botrychium lunaria’ Swartz. The edition of the Latin text includes its translation into Spanish.

  10. Order of 25 March 1981 concerning the approval of special form radioactive materials in sealed sources

    International Nuclear Information System (INIS)

    1981-01-01

    This order determines the models of sealed sources which constitute special form radioactive materials within the meaning of the Order of 24 November 1977 concerning the characteristics of such materials. (NEA) [fr

  11. Johann Jakob Wettstein. New Sources, New Problems, and New Possibilities for Digital Research

    Directory of Open Access Journals (Sweden)

    Jan Krans

    2016-04-01

    Full Text Available Johann Jakob Wettstein (1683-1754 worked almost all his life toward the publication of his landmark 1751-52 edition of the Greek New Testament. In recent years, a large number of previously unknown sources on and by Wettstein has come to light, scattered over libraries in Europe, that provide new insights into his life and his New Testament project. This paper explores the diversity of these sources, their genres, their connections, their state of conservation and accessibility and the like. Starting from the idea that the collection offers an excellent opportunity for mapping a single scholar’s projects and international networks over time and space, it envisages a project that brings together this wealth of material. It asks what challenges and possibilities for international digital research the collection entails and formulates the desiderata concerning the necessary digital infrastructure and collaboration across traditional scholarly boundaries.

  12. Genes (including RNA editing information) - RMG | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available t tested T: transcribed N: not transcribed Editing site Editing site N: not transcribed Previous reports on ...editing sites Previous reports on editing sites Strand Strand S: sense A: antisense exon1 start Start positi

  13. Understanding solids: the science of materials

    CERN Document Server

    Tilley, Richard J. D.

    2013-01-01

    This edition contains new sections on the use of computing methods to solve materials problems and has been thoroughly updated to include the many developments and advances made in the past 10 years, e.g.  batteries, solar cells, lighting technology, laser...

  14. Ramón Reichert and Annika Richterich, eds., Digital Material/ism Vol. 1, Issue 1 – Digital Culture and Society

    OpenAIRE

    Pournara, Lizzy

    2017-01-01

    Ramón Reichert and Annika Richterich, eds., Digital Material/ism Vol. 1, Issue 1 – Digital Culture and Society Bielefeld: [transcript] Verlag, 2015. ISBN 978-3-8376-3153-1. Lizzy Pournara Aristotle University of Thessaloniki The issue Digital Material/ism edited by Ramón Reichert and Annika Richterich inaugurates the first volume of the journal Digital Culture & Society. The significance of this volume’s work lies in its attempt to redress the concept of materiality in digital environments an...

  15. Regulatory control of radiation sources and radioactive materials in the Czech Republic

    International Nuclear Information System (INIS)

    Drabova, D.; Prouza, Z.

    2001-01-01

    The paper describes legal and regulatory provisions for radiation protection and safe use of sources of ionizing radiation in the Czech Republic with special emphasis on aspects of bringing activities under regulatory control and releasing them from it. It covers the development of a new legal framework, the work of the regulatory body, an overview of sources in use and provisions to achieve effective regulatory control of facilities and releases of radioactive material into the environment. Also, it describes reported unusual events with a proposed scheme for their classification and evaluation. (author)

  16. OpCost: an open-source system for estimating costs of stand-level forest operations

    Science.gov (United States)

    Conor K. Bell; Robert F. Keefe; Jeremy S. Fried

    2017-01-01

    This report describes and documents the OpCost forest operations cost model, a key component of the BioSum analysis framework. OpCost is available in two editions: as a callable module for use with BioSum, and in a stand-alone edition that can be run directly from R. OpCost model logic and assumptions for this open-source tool are explained, references to the...

  17. Multilayer Thin Films Sequential Assembly of Nanocomposite Materials

    CERN Document Server

    Decher, Gero

    2012-01-01

    This second, comprehensive edition of the pioneering book in this field has been completely revised and extended, now stretching to two volumes. The result is a comprehensive summary of layer-by-layer assembled, truly hybrid nanomaterials and thin films, covering organic, inorganic, colloidal, macromolecular and biological components, plus the assembly of nanoscale films derived from them on surfaces. Praise for the first edition: "... highly recommended to anyone interested in the field... and to scientists and researchers active in materials development..." –Polymer News With contri

  18. Advanced quantum mechanics materials and photons

    CERN Document Server

    Dick, Rainer

    2016-01-01

    In this updated and expanded second edition of a well-received and invaluable textbook, Prof. Dick emphasizes the importance of advanced quantum mechanics for materials science and all experimental techniques which employ photon absorption, emission, or scattering. Important aspects of introductory quantum mechanics are covered in the first seven chapters to make the subject self-contained and accessible for a wide audience. Advanced Quantum Mechanics, Materials and Photons can therefore be used for advanced undergraduate courses and introductory graduate courses which are targeted towards students with diverse academic backgrounds from the Natural Sciences or Engineering. To enhance this inclusive aspect of making the subject as accessible as possible Appendices A and B also provide introductions to Lagrangian mechanics and the covariant formulation of electrodynamics. This second edition includes an additional 62 new problems as well as expanded sections on relativistic quantum fields and applications of�...

  19. The Elgar companion to social economics : Second edition

    NARCIS (Netherlands)

    Davis, John B.; Dolfsma, Wilfred

    2015-01-01

    Social economics is a dynamic and growing field that emphasizes the key roles social values play in the economy and economic life. This second edition of the Elgar Companion to Social Economics revises all chapters from the first edition, and adds important new chapters to reflect the expansion and

  20. Gene-Editing: Interpretation of Current Law and Legal Policy

    OpenAIRE

    Kim, Na-Kyoung

    2017-01-01

    ABSTRACT With the development of the third-generation gene scissors, CRISPR-Cas9, concerns are being raised about ethical and social repercussions of the new gene-editing technology. In this situation, this article explores the legislation and interpretation of the positive laws in South Korea. The BioAct does not specify and regulate 'gene editing' itself. However, assuming that genetic editing is used in the process of research and treatment, we can look to the specific details of the regul...

  1. WannierTools: An open-source software package for novel topological materials

    Science.gov (United States)

    Wu, QuanSheng; Zhang, ShengNan; Song, Hai-Feng; Troyer, Matthias; Soluyanov, Alexey A.

    2018-03-01

    We present an open-source software package WannierTools, a tool for investigation of novel topological materials. This code works in the tight-binding framework, which can be generated by another software package Wannier90 (Mostofi et al., 2008). It can help to classify the topological phase of a given material by calculating the Wilson loop, and can get the surface state spectrum, which is detected by angle resolved photoemission (ARPES) and in scanning tunneling microscopy (STM) experiments. It also identifies positions of Weyl/Dirac points and nodal line structures, calculates the Berry phase around a closed momentum loop and Berry curvature in a part of the Brillouin zone (BZ).

  2. Regulatory factors governing adenosine-to-inosine (A-to-I) RNA editing.

    Science.gov (United States)

    Hong, HuiQi; Lin, Jaymie Siqi; Chen, Leilei

    2015-03-31

    Adenosine-to-inosine (A-to-I) RNA editing, the most prevalent mode of transcript modification in higher eukaryotes, is catalysed by the adenosine deaminases acting on RNA (ADARs). A-to-I editing imposes an additional layer of gene regulation as it dictates various aspects of RNA metabolism, including RNA folding, processing, localization and degradation. Furthermore, editing events in exonic regions contribute to proteome diversity as translational machinery decodes inosine as guanosine. Although it has been demonstrated that dysregulated A-to-I editing contributes to various diseases, the precise regulatory mechanisms governing this critical cellular process have yet to be fully elucidated. However, integration of previous studies revealed that regulation of A-to-I editing is multifaceted, weaving an intricate network of auto- and transregulations, including the involvement of virus-originated factors like adenovirus-associated RNA. Taken together, it is apparent that tipping of any regulatory components will have profound effects on A-to-I editing, which in turn contributes to both normal and aberrant physiological conditions. A complete understanding of this intricate regulatory network may ultimately be translated into new therapeutic strategies against diseases driven by perturbed RNA editing events. Herein, we review the current state of knowledge on the regulatory mechanisms governing A-to-I editing and propose the role of other co-factors that may be involved in this complex regulatory process.

  3. Requirements for Certification [of] Teachers, Counselors, Librarians, Administrators for Elementary Schools, Secondary Schools, Junior Colleges. Forty-eighth Edition, 1983-84.

    Science.gov (United States)

    Woellner, Elizabeth H.

    This edition of "Requirements for Certification" updates pertinent information on certification requirements for teachers, administrators, librarians, counselors, and other school personnel in each state in the United States. Outlines are provided of recommendations on certification by regional and national associations, and sources of information…

  4. Volume-editing tools for three-dimensional imaging of CT data

    International Nuclear Information System (INIS)

    Ney, D.R.; Fishman, E.K.

    1989-01-01

    Three-dimensional imaging of complex structures relies heavily on the ability to edit the routine CT scans to provide an optimal view of the area in question. The authors present a series of strategies for defining the volume editing tools. The authors have developed a series of editing tools that allow the operator to edit critical areas out of an image. The tools are based on a variety of imaging strategies that are implemented depending on the difficulty of separating two structures. The tools combine rectangular masking, threshold base filling, arbitrary curve-based masking, masking, threshold base filling, arbitrary curve-based masking, and object definition via edge detection

  5. Hackers Heroes of the Computer Revolution - 25th Anniversary Edition

    CERN Document Server

    Levy, Steven

    2010-01-01

    This 25th anniversary edition of Steven Levy's classic book traces the exploits of the computer revolution's original hackers -- those brilliant and eccentric nerds from the late 1950s through the early '80s who took risks, bent the rules, and pushed the world in a radical new direction. With updated material from noteworthy hackers such as Bill Gates, Mark Zuckerberg, Richard Stallman, and Steve Wozniak, Hackers is a fascinating story that begins in early computer research labs and leads to the first home computers. Levy profiles the imaginative brainiacs who found clever and unorthodox sol

  6. Qualitative Data Analysis: A Methods Sourcebook. Third Edition

    Science.gov (United States)

    Miles, Matthew B.; Huberman, A. Michael; Saldana, Johnny

    2014-01-01

    The Third Edition of Miles & Huberman's classic research methods text is updated and streamlined by Johnny Saldaña, author of "The Coding Manual for Qualitative Researchers." Several of the data display strategies from previous editions are now presented in re-envisioned and reorganized formats to enhance reader accessibility and…

  7. FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling

    Directory of Open Access Journals (Sweden)

    Jonathan Arias-Fuenzalida

    2017-11-01

    Full Text Available Genome editing and human induced pluripotent stem cells hold great promise for the development of isogenic disease models and the correction of disease-associated mutations for isogenic tissue therapy. CRISPR-Cas9 has emerged as a versatile and simple tool for engineering human cells for such purposes. However, the current protocols to derive genome-edited lines require the screening of a great number of clones to obtain one free of random integration or on-locus non-homologous end joining (NHEJ-containing alleles. Here, we describe an efficient method to derive biallelic genome-edited populations by the use of fluorescent markers. We call this technique FACS-assisted CRISPR-Cas9 editing (FACE. FACE allows the derivation of correctly edited polyclones carrying a positive selection fluorescent module and the exclusion of non-edited, random integrations and on-target allele NHEJ-containing cells. We derived a set of isogenic lines containing Parkinson's-disease-associated mutations in α-synuclein and present their comparative phenotypes.

  8. Insects feeding on cadavers as an alternative source of human genetic material

    Directory of Open Access Journals (Sweden)

    Rafał Skowronek

    2015-03-01

    Full Text Available In some criminal cases, the use of classical sources of human genetic material is difficult or even impossible. One solution may be the use of insects, especially blowfly larvae which feed on corpses. A recent review of case reports and experimental studies available in biomedical databases has shown that insects can be a valuable source of human mitochondrial and genomic deoxyribonucleic acid (DNA, allowing for an effective analysis of hypervariable region (HVR sequences and short tandem repeat (STR profiles, respectively. The optimal source of human DNA is the crop (a part of the gut of active third-instar blowfly larvae. Pupae and insect faeces can be also used in forensic genetic practice instead of the contents of the alimentary tract.

  9. Sheath physics and materials science results from recent plasma source ion implantation experiments

    International Nuclear Information System (INIS)

    Conrad, J.R.; Radtke, J.L.; Dodd, R.A.; Worzala, F.J.

    1987-01-01

    Plasma Source Ion Implantation (PSII) is a surface modification technique which has been optimized for ion-beam processing of materials. PSII departs radically from conventional implantation by circumventing the line of sight restriction inherent in conventional ion implantation. The authors used PSII to implant cutting tools and dies and have demonstrated substantial improvements in lifetime. Recent results on plasma physics scaling laws, microstructural, mechanical, and tribological properties of PSII-implanted materials are presented

  10. A Hard Month's Work in Manila. Securing Radioactive Sources (Arabic Edition)

    International Nuclear Information System (INIS)

    Potterton, Louise

    2013-01-01

    Security managers keep a watchful eye on spent radioactive sources. These disused sources, which served myriad purposes in medicine, industry and research, present a potential security threat; they could be obtained by terrorists to construct a dirty bomb. To ensure nuclear security and safety, it is essential to package, store and eventually dispose of these spent sources safely and securely. In some cases, that is easier said than done. For instance, removing an old and highly radioactive source from a medical device is difficult and dangerous. Imagine doing this remotely, using manipulators, in temperatures of up to 35 degrees and over 20 times. This is exactly what the IAEA, together with the South African Nuclear Energy Corporation (Necsa), successfully achieved in March and April 2013 at the Philippine Nuclear Research Institute (PNRI) in Manila. (author)

  11. A Hard Month's Work in Manila. Securing Radioactive Sources (Chinese Edition)

    International Nuclear Information System (INIS)

    Potterton, Louise

    2013-01-01

    Security managers keep a watchful eye on spent radioactive sources. These disused sources, which served myriad purposes in medicine, industry and research, present a potential security threat; they could be obtained by terrorists to construct a dirty bomb. To ensure nuclear security and safety, it is essential to package, store and eventually dispose of these spent sources safely and securely. In some cases, that is easier said than done. For instance, removing an old and highly radioactive source from a medical device is difficult and dangerous. Imagine doing this remotely, using manipulators, in temperatures of up to 35 degrees and over 20 times. This is exactly what the IAEA, together with the South African Nuclear Energy Corporation (Necsa), successfully achieved in March and April 2013 at the Philippine Nuclear Research Institute (PNRI) in Manila. (author)

  12. A Hard Month's Work in Manila. Securing Radioactive Sources (Spanish Edition)

    International Nuclear Information System (INIS)

    Potterton, Louise

    2013-01-01

    Security managers keep a watchful eye on spent radioactive sources. These disused sources, which served myriad purposes in medicine, industry and research, present a potential security threat; they could be obtained by terrorists to construct a dirty bomb. To ensure nuclear security and safety, it is essential to package, store and eventually dispose of these spent sources safely and securely. In some cases, that is easier said than done. For instance, removing an old and highly radioactive source from a medical device is difficult and dangerous. Imagine doing this remotely, using manipulators, in temperatures of up to 35 degrees and over 20 times. This is exactly what the IAEA, together with the South African Nuclear Energy Corporation (Necsa), successfully achieved in March and April 2013 at the Philippine Nuclear Research Institute (PNRI) in Manila. (author)

  13. A Hard Month's Work in Manila. Securing Radioactive Sources (Russian Edition)

    International Nuclear Information System (INIS)

    Potterton, Louise

    2013-01-01

    Security managers keep a watchful eye on spent radioactive sources. These disused sources, which served myriad purposes in medicine, industry and research, present a potential security threat; they could be obtained by terrorists to construct a dirty bomb. To ensure nuclear security and safety, it is essential to package, store and eventually dispose of these spent sources safely and securely. In some cases, that is easier said than done. For instance, removing an old and highly radioactive source from a medical device is difficult and dangerous. Imagine doing this remotely, using manipulators, in temperatures of up to 35 degrees and over 20 times. This is exactly what the IAEA, together with the South African Nuclear Energy Corporation (Necsa), successfully achieved in March and April 2013 at the Philippine Nuclear Research Institute (PNRI) in Manila. (author)

  14. 76 FR 46290 - EPA Seeking Input Materials Measurement; Municipal Solid Waste (MSW), Recycling, and Source...

    Science.gov (United States)

    2011-08-02

    ... States'' as part of a broader discussion about sustainable materials management. This information will be..., as well as its transparency. There is also a growing need for a more holistic assessment of how... sustainable management of these materials through safe recycling and source reduction. The Agency will...

  15. The Star Wars franchise, fan edits, and Lucasfilm [symposium

    Directory of Open Access Journals (Sweden)

    Forrest Phillips

    2012-03-01

    Full Text Available Fan edits assert that fan authority is on par with that of a work's original creator; this authority is generated not only through the argument, but through the structure of the text itself. Fan edits adhere to classical filmmaking techniques, creating coherent plots and editing for continuity. These recut texts are emblematic of current ownership debates; they are the read/write culture brought to fandom. The Star Wars series of films are among the most frequently recut texts and are my focus here.

  16. Decree of 4 November 1982 on conditions for notification of possession of special fissile materials and source materials and for keeping accounts thereof

    International Nuclear Information System (INIS)

    1982-01-01

    This Decree lays down a detailed procedure for notification of the possession and accounting of special fissile materials and source materials. The Decree was made in pursuance of Decree No. 185 of 13 February 1964 of the President of the Republic concerning radiation protection and licensing procedures. (NEA) [fr

  17. Genome editing: progress and challenges for medical applications

    Directory of Open Access Journals (Sweden)

    Dana Carroll

    2016-11-01

    Full Text Available Editorial summary The development of the CRISPR-Cas platform for genome editing has greatly simplified the process of making targeted genetic modifications. Applications of genome editing are expected to have a substantial impact on human therapies through the development of better animal models, new target discovery, and direct therapeutic intervention.

  18. ELECTRONIC PROFESSIONAL EDITIONS IN THE SYSTEM OF SCIENTIFIC PERIODICALS: STATE AND PROSPECTS

    Directory of Open Access Journals (Sweden)

    Nataliia M. Kropocheva

    2014-02-01

    Full Text Available The article highlights relevant current problems concerning the formation, present state and prospects of the development of the native electronic professional editions on pedagogy. The historical overview of the development of the electronic books in the world and in Ukraine in general, and also including the professional editions was made. It was conducted the analysis of national and international legal framework for existing electronic editions, as well as researched the structure and software of the native electronic professional editions on pedagogy. Based on the results, it was formulated the conclusions and developed some suggestions for the improvement of electronic editions.

  19. Apparatus for measuring moisture in moving bulk material using a lithium-7 radiation source

    International Nuclear Information System (INIS)

    Ashe, J.B.

    1976-01-01

    A nucleonic device is described for measuring the moisture content of bulk materials using a radioisotopic fast-neutron source such as lithium-7 admixed with an alpha-particle emitter such as americium-241 as a means of minimizing the thickness of the layer of bulk material required proximate to the moisture sensor for a neutron-reflection moisture gauge for proper operation of said gauge. Minimization of the required thickness of the bulk material permits use of a neutron-reflection moisture gauge for measurements of bulk materials on lightly-loaded belts and other types of conveyors where measurements have previously been impracticable

  20. School Finance: Achieving High Standards with Equity and Efficiency. Third Edition.

    Science.gov (United States)

    King, Richard A.; Swanson, Austin D.; Sweetland, Scott R.

    This third edition of this book explores traditional economic and political models and contemporary issues that affect the social, political, and economic state of schools. Like the previous two editions, this edition takes a balanced approach to understanding school finance issues by using paradigms of both the economist and the political…

  1. Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum

    KAUST Repository

    Liew, Yi Jin

    2017-03-01

    RNA editing is a rare post-transcriptional event that provides cells with an additional level of gene expression regulation. It has been implicated in various processes including adaptation, viral defence and RNA interference; however, its potential role as a mechanism in acclimatization has just recently been recognised. Here, we show that RNA editing occurs in 1.6% of all nuclear-encoded genes of Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. All base-substitution edit types were present, and statistically significant motifs were associated with three edit types. Strikingly, a subset of genes exhibited condition-specific editing patterns in response to different stressors that resulted in significant increases of non-synonymous changes. We posit that this previously unrecognised mechanism extends this organism’s capability to respond to stress beyond what is encoded by the genome. This in turn may provide further acclimatization capacity to these organisms, and by extension, their coral hosts.

  2. Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum

    KAUST Repository

    Liew, Yi Jin; Li, Yong; Baumgarten, Sebastian; Voolstra, Christian R.; Aranda, Manuel

    2017-01-01

    RNA editing is a rare post-transcriptional event that provides cells with an additional level of gene expression regulation. It has been implicated in various processes including adaptation, viral defence and RNA interference; however, its potential role as a mechanism in acclimatization has just recently been recognised. Here, we show that RNA editing occurs in 1.6% of all nuclear-encoded genes of Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. All base-substitution edit types were present, and statistically significant motifs were associated with three edit types. Strikingly, a subset of genes exhibited condition-specific editing patterns in response to different stressors that resulted in significant increases of non-synonymous changes. We posit that this previously unrecognised mechanism extends this organism’s capability to respond to stress beyond what is encoded by the genome. This in turn may provide further acclimatization capacity to these organisms, and by extension, their coral hosts.

  3. [Advances in CRISPR-Cas-mediated genome editing system in plants].

    Science.gov (United States)

    Wang, Chun; Wang, Kejian

    2017-10-25

    Targeted genome editing technology is an important tool to study the function of genes and to modify organisms at the genetic level. Recently, CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins) system has emerged as an efficient tool for specific genome editing in animals and plants. CRISPR-Cas system uses CRISPR-associated endonuclease and a guide RNA to generate double-strand breaks at the target DNA site, subsequently leading to genetic modifications. CRISPR-Cas system has received widespread attention for manipulating the genomes with simple, easy and high specificity. This review summarizes recent advances of diverse applications of the CRISPR-Cas toolkit in plant research and crop breeding, including expanding the range of genome editing, precise editing of a target base, and efficient DNA-free genome editing technology. This review also discusses the potential challenges and application prospect in the future, and provides a useful reference for researchers who are interested in this field.

  4. Efficient parallel algorithms for string editing and related problems

    Science.gov (United States)

    Apostolico, Alberto; Atallah, Mikhail J.; Larmore, Lawrence; Mcfaddin, H. S.

    1988-01-01

    The string editing problem for input strings x and y consists of transforming x into y by performing a series of weighted edit operations on x of overall minimum cost. An edit operation on x can be the deletion of a symbol from x, the insertion of a symbol in x or the substitution of a symbol x with another symbol. This problem has a well known O((absolute value of x)(absolute value of y)) time sequential solution (25). The efficient Program Requirements Analysis Methods (PRAM) parallel algorithms for the string editing problem are given. If m = ((absolute value of x),(absolute value of y)) and n = max((absolute value of x),(absolute value of y)), then the CREW bound is O (log m log n) time with O (mn/log m) processors. In all algorithms, space is O (mn).

  5. Genome editing: a robust technology for human stem cells.

    Science.gov (United States)

    Chandrasekaran, Arun Pandian; Song, Minjung; Ramakrishna, Suresh

    2017-09-01

    Human pluripotent stem cells comprise induced pluripotent and embryonic stem cells, which have tremendous potential for biological and therapeutic applications. The development of efficient technologies for the targeted genome alteration of stem cells in disease models is a prerequisite for utilizing stem cells to their full potential. Genome editing of stem cells is possible with the help of synthetic nucleases that facilitate site-specific modification of a gene of interest. Recent advances in genome editing techniques have improved the efficiency and speed of the development of stem cells for human disease models. Zinc finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated system are powerful tools for editing DNA at specific loci. Here, we discuss recent technological advances in genome editing with site-specific nucleases in human stem cells.

  6. The discussion of execution about HAF603 of 2008 edition

    International Nuclear Information System (INIS)

    Shen Wei; Lu Gaoshang; Sun Haipeng

    2010-01-01

    The general situation about nuclear power welder qualification standards of 1995 and 2008 editions is introduced in this paper, and the differences between them are analyzed. Combining with the practical experiences in the supervisions of welder qualification, the authors point out the main problems faced in the execution of 2008 edition HAF603, and put forward the advices and opinions in the execution of 2008 edition HAF603. (authors)

  7. Genome editing for crop improvement: Challenges and opportunities.

    Science.gov (United States)

    Abdallah, Naglaa A; Prakash, Channapatna S; McHughen, Alan G

    2015-01-01

    Genome or gene editing includes several new techniques to help scientists precisely modify genome sequences. The techniques also enables us to alter the regulation of gene expression patterns in a pre-determined region and facilitates novel insights into the functional genomics of an organism. Emergence of genome editing has brought considerable excitement especially among agricultural scientists because of its simplicity, precision and power as it offers new opportunities to develop improved crop varieties with clear-cut addition of valuable traits or removal of undesirable traits. Research is underway to improve crop varieties with higher yields, strengthen stress tolerance, disease and pest resistance, decrease input costs, and increase nutritional value. Genome editing encompasses a wide variety of tools using either a site-specific recombinase (SSR) or a site-specific nuclease (SSN) system. Both systems require recognition of a known sequence. The SSN system generates single or double strand DNA breaks and activates endogenous DNA repair pathways. SSR technology, such as Cre/loxP and Flp/FRT mediated systems, are able to knockdown or knock-in genes in the genome of eukaryotes, depending on the orientation of the specific sites (loxP, FLP, etc.) flanking the target site. There are 4 main classes of SSN developed to cleave genomic sequences, mega-nucleases (homing endonuclease), zinc finger nucleases (ZFNs), transcriptional activator-like effector nucleases (TALENs), and the CRISPR/Cas nuclease system (clustered regularly interspaced short palindromic repeat/CRISPR-associated protein). The recombinase mediated genome engineering depends on recombinase (sub-) family and target-site and induces high frequencies of homologous recombination. Improving crops with gene editing provides a range of options: by altering only a few nucleotides from billions found in the genomes of living cells, altering the full allele or by inserting a new gene in a targeted region of

  8. CrEdit: CRISPR mediated multi-loci gene integration in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Ronda, Carlotta; Maury, Jerome; Jakociunas, Tadas

    2015-01-01

    episomal vectors. Existing approaches for achieving stable simultaneous genome integrations of multiple DNA fragments often result in relatively low integration efficiencies and furthermore rely on the use of selection markers. Results: Here, we have developed a novel method, CrEdit (CRISPR/Cas9 mediated...... genome Editing), which utilizes targeted double strand breaks caused by CRISPR/Cas9 to significantly increase the efficiency of homologous integration in order to edit and manipulate genomic DNA. Using CrEdit, the efficiency and locus specificity of targeted genome integrations reach close to 100...

  9. Penetration Tester's Open Source Toolkit

    CERN Document Server

    Faircloth, Jeremy

    2011-01-01

    Great commercial penetration testing tools can be very expensive and sometimes hard to use or of questionable accuracy. This book helps solve both of these problems. The open source, no-cost penetration testing tools presented do a great job and can be modified by the user for each situation. Many tools, even ones that cost thousands of dollars, do not come with any type of instruction on how and in which situations the penetration tester can best use them. Penetration Tester's Open Source Toolkit, Third Edition, expands upon existing instructions so that a professional can get the most accura

  10. Regulatory control of radiation sources and radioactive materials in Ireland

    International Nuclear Information System (INIS)

    McGarry, A.T.; Fenton, D.; O'Flaherty, T.

    2001-01-01

    The primary legislation governing safety in uses of ionizing radiation in Ireland is the Radiological Protection Act, 1991. This Act provided for the establishment in 1992 of the Radiological Protection Institute of Ireland, and gives the Institute the functions and powers which enable it to be the regulatory body for all matters relating to ionizing radiation. A Ministerial Order made under the Act in 2000 consolidates previous regulations and, in particular, provides for the implementation in Irish law of the 1996 European Union Directive which lays down basic safety standards for the protection of the health of workers and the general public against the dangers arising from ionizing radiation. Under the legislation, the custody, use and a number of other activities involving radioactive substances and irradiating apparatus require a licence issued by the Institute. Currently some 1260 licences are in force. Of these, some 850 are in respect of irradiating apparatus only and are issued principally to dentists and veterinary surgeons. The remaining licences involve sealed radiation sources and/or unsealed radioactive substances used in medicine, industry or education. A schedule attached to each licence fully lists the sealed sources to which the licence applies, and also the quantities of radioactive substances which may be acquired or held under the licence. It is an offence to dispose of, or otherwise relinquish possession of, any licensable material other than in accordance with terms and conditions of the licence. Disused sources are returned to the original supplier or, where this is not possible, stored under licence by the licensee who used them. Enforcement of the licensing provisions relies primarily on the programme of inspection of licensees, carried out by the Institute's inspectors. The Institute's Regulatory Service has a complement of four inspectors, one of whom is the Manager of the Service. The Manager reports to one of the Institute's Principal

  11. Edition des Corpus areopagiticum slavicum

    Directory of Open Access Journals (Sweden)

    Dieter Fahl

    2005-12-01

    Full Text Available An Edition of the Corpus areopagiticum slavicum In the fourteenth century, the monk Isaiah of the holy Mount Athos translated the writings of pseudo-Dionysius the Areopagite (c. end of the 5th century, core texts for Eastern and Western European theological and philosophical thought, from Greek into Church Slavonic. This first Slavic translation of Dionysius’ oeuvre (“De Coelesti Hierarchia,” “De Ecclesiastica Hierarchia,” “De Divinis Nominibus,” “De Mystica Theologia,” the epistles and scholia, which played a significant role in the development of Slavic culture, Orthodox Slavic socio-political theory and praxis, is still central to the study of Slavia Orthodoxa. A working group of German and Russian scholars has completed an edition of the translator’s Church Slavonic autograph with an en face reconstruction of the Greek text used by the translator and philological commentary. A Church Slavonic-Greek and Greek-Church Slavonic dictionary of this edition, currently in preparation, plans to make the terminology used in this influential translation accessible to interdisciplinary researchers. For the first time, the Church Slavonic lexica of this corpus, a substantial part of which was coined by the translator, will be registered in an index of words and forms.

  12. Safety of radiation sources and the security of radioactive materials in Saudi Arabia

    International Nuclear Information System (INIS)

    Alarfaj, A.M.

    1998-01-01

    The present status of the safety of radiation sources and the security of radioactive materials in Saudi Arabia is reviewed in details. Hazards and potential threat, material control and responsible parties, in addition to management and the technical requirements, are the main topics that are discussed. Some interest is given to the responsibilities of the regulatory authority, with special emphasis on the role of King Abdulaziz city for Science and Technology as a national competent authority. (author)

  13. Direct G-code manipulation for 3D material weaving

    Science.gov (United States)

    Koda, S.; Tanaka, H.

    2017-04-01

    The process of conventional 3D printing begins by first build a 3D model, then convert to the model to G-code via a slicer software, feed the G-code to the printer, and finally start the printing. The most simple and popular 3D printing technique is Fused Deposition Modeling. However, in this method, the printing path that the printer head can take is restricted by the G-code. Therefore the printed 3D models with complex pattern have structural errors like holes or gaps between the printed material lines. In addition, the structural density and the material's position of the printed model are difficult to control. We realized the G-code editing, Fabrix, for making a more precise and functional printed model with both single and multiple material. The models with different stiffness are fabricated by the controlling the printing density of the filament materials with our method. In addition, the multi-material 3D printing has a possibility to expand the physical properties by the material combination and its G-code editing. These results show the new printing method to provide more creative and functional 3D printing techniques.

  14. Country Nuclear Power Profiles - 2010 Edition

    International Nuclear Information System (INIS)

    2010-08-01

    The Country Nuclear Power Profiles compiles background information on the status and development of nuclear power programs in Member States. It consists of organizational and industrial aspects of nuclear power programs and provides information about the relevant legislative, regulatory, and international framework in each country. Its descriptive and statistical overview of the overall economic, energy, and electricity situation in each country, and its nuclear power framework is intended to serve as an integrated source of key background information about nuclear power programs in the world. The preparation of Country Nuclear Power Profiles (CNPP) was initiated in 1990s. It responded to a need for a database and a technical publication containing a description of the energy and economic situation, the energy and the electricity sector, and the primary organizations involved in nuclear power in IAEA Member States. This is the 2010 edition issued on CD-ROM and Web pages. It updates the country information for 48 countries. The CNPP is updated based on information voluntarily provided by participating IAEA Member States. Participants include the 29 countries that have operating nuclear power plants, as well as 19 countries having past or planned nuclear power programmes (Bangladesh, Belarus, Chile, Egypt, Ghana, Indonesia, the Islamic Republic of Iran, Italy, Jordan, Kazakhstan, Lithuania, Morocco, Nigeria, Philippines, Poland, Thailand, Tunisia, Turkey and Vietnam). For the 2010 edition, 24 countries provided updated or new profiles. For the other countries, the IAEA updated the profile statistical tables on nuclear power, energy development, and economic indicators based on information from IAEA and World Bank databases. The CNPP reports have been prepared by each Member State in accordance with the IAEA format. The IAEA is not responsible for the content of these reports

  15. Five Challenges for Intelligent Cinematography and Editing

    OpenAIRE

    Ronfard , Rémi

    2017-01-01

    International audience; In this position paper, we propose five challenges for advancing the state of the art in intelligent cinematography and editing by taking advantage of the huge quantity of cinematographic data (movies) and metadata (movie scripts) available in digital formats. This suggests a data-driven approach to intelligent cinematography and editing, with at least five scientific bottlenecks that need to be carefully analyzed and resolved.we briefly describe them and suggest some ...

  16. Building materials as a source of a possible radiation exposure of the population

    International Nuclear Information System (INIS)

    Pensko, J.; Burkart, W.

    1986-12-01

    Two main pathways of exposure contribute to the human radiation exposure indoors: external whole body irradiation from gamma-rays originating from the walls, and exposure of lung tissue by alpha-rays emitted by radon daughters present in the inhaled air. Natural radioactive elements present in building materials produce both kinds of radioactive exposure. Uranium, thorium and potassium are sources of gamma radiations. Materials containing radium can create an alpha-radiation hazard for the human respiratory system through the exhalation of radon from room surfaces. Measurements of the natural radioactivity of building materials made in several European countries are reviewed. A preliminary assessment of the radioactivity content of potentially hazardous materials on the Swiss market shows elevated levels in imported phosphogypsum and tuff. (author)

  17. The Monthly Sky Guide: Sixth Edition

    Science.gov (United States)

    Ridpath, Ian; Tirion, Wil

    2003-06-01

    The latest edition of Ian Ridpath and Wil Tirion's popular guide to the night sky is updated for planet positions and forthcoming eclipses up to the end of the year 2007. With one chapter for each month of the year, this is an easy-to-use handbook for anyone wanting to identify constellations, star clusters, nebulae, to plot the movement of planets, or witness solar and lunar eclipses. Most of the features discussed are visible to the naked eye and all can be seen with a small telescope or binoculars. Ian Ridpath has been a full-time writer, broadcaster and lecturer on astronomy and space for more than twenty-five years. He has written and edited more than 40 books, including A Comet Called Haley (Cambridge, 1985). Wil Tirion made his first star map in 1977. It showed stars to the magnitude of 6.5 and was issued as a set of maps by the British Astronomical Association in 1981. He has illustrated numerous books and magazines, including The Cambridge Star Atlas (Cambridge, 2001). Previous Edition Pb (1999): 0-521-66771-2

  18. A spectroscopic tool for identifying sources of origin for materials of military interest

    Science.gov (United States)

    Miziolek, Andrzej W.; De Lucia, Frank C.

    2014-05-01

    There is a need to identify the source of origin for many items of military interest, including ammunition and weapons that may be circulated and traded in illicit markets. Both fieldable systems (man-portable or handheld) as well as benchtop systems in field and home base laboratories are desired for screening and attribution purposes. Laser Induced Breakdown Spectroscopy (LIBS) continues to show significant capability as a promising new tool for materials identification, matching, and provenance. With the use of the broadband, high resolution spectrometer systems, the LIBS devices can not only determine the elemental inventory of the sample, but they are also capable of elemental fingerprinting to signify sources of origin of various materials. We present the results of an initial study to differentiate and match spent cartridges from different manufacturers and countries. We have found that using Partial Least Squares Discriminant Analysis (PLS-DA) we are able to achieve on average 93.3% True Positives and 5.3% False Positives. These results add to the large body of publications that have demonstrated that LIBS is a particularly suitable tool for source of origin determinations.

  19. CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_TRMM-PFM_Edition1)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2000-12-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  20. A dictionary of altitudes in the United States (second edition)

    Science.gov (United States)

    Gannett, Henry

    1891-01-01

    I have the honor to transmit herewith the manuscript of a second edition of a Dictionary of Altitudes, the first edition having been published in 1884. The present work is considerably enlarged, mainly by the addition of determinations of altitudes by railroads. Besides the additions of matter, the principal change from the earlier edition consists in the substitution of a single alphabetic arrangement throughout the work for an alphabetic arrangement by States.

  1. Nest materials as a source of genetic data for avian ecological studies

    Science.gov (United States)

    Pearce, J.M.; Fields, R.L.; Scribner, K.T.

    1997-01-01

    We examined the utility of feathers and egg shell membranes, deposited in the nests of Spectacled Eiders (Somateria fischeri), as a source of DNA for genetic studies at both the population and individual level. The potential for feather DNA contamination as a result of female behavioral interactions (e.g. nest parasitism), reuse of nest sites from previous years, or other unknown occurrences was acknowledged and specifically tested. DNA was successfully extracted from both feathers and egg shell membranes and waterfowl microsatellite loci were used to construct individual genotypes. We found no difference in the genotypes obtained from nest feathers or blood of the incubating female. Detection of nest feather contamination was possible with as little as one feather when samples from multiple females were intentionally mixed. Triplicate DNA extractions from 33 nests provided a means of detecting contamination in 3 nests. Egg membranes proved a viable source of offspring DNA and can contribute valuable data to investigations of parentage when assayed jointly with maternal feather DNA. Nest materials provide an efficient, non-invasive method of genetic sampling that can be readily incorporated into field research. However, the natural history traits and mating strategies of a species must be considered during sample collection to identify the possible sources of nest materials (e.g., paternal, maternal, parasite, etc.). Specific experiments should also be designed to test sampling assumptions.

  2. Directory of national competent authorities' approval certificates for package design, special form material and shipment of radioactive material. 2002 ed

    International Nuclear Information System (INIS)

    2002-08-01

    The current edition of the transport Regulations was published in 1996 and is more commonly referred to as 'ST-1'. Earlier Editions were known as Safety Series No. 6. The latest English reprint (2000) is now identified as TS-R-1 (ST-1, Revised). The transport Regulations elaborate requirements for the design, fabrication and maintenance of packaging as well as those for preparation, consigning, handling, carriage, storage in transit and receipt of the packages at final destination. Approval issued in the form of certificates is required for the design or shipment of packages. This report supersedes IAEA-TECDOC-1237 Directory of National Competent Authorities' Approval Certificates for Package Design, Special Form Material and Shipment of Radioactive Material, 2001 Edition. It is distributed worldwide to the IAEA Member States' competent authorities for transport, and other entities who have requested copies. Electronic copies of the main data file are provided to registered users of the PACKTRAM database. The information contained in this report is given in six tables. In each of these, information is presented in alphabetical order based on the certificate number. Tables 1 to 4 present administrative data including issue and expiry dates, package identification, package serial numbers, modes for which the package/shipment is approved and the edition of the IAEA Transport Safety Regulations on which the approval has been based. The technical information on package mass, authorized contents, and detailed and general description of the package are contained in Table 5. Table 6 shows the certificates reported to the Secretariat by each participating Member State

  3. The impact of genome editing on the introduction of monogenic traits in livestock.

    Science.gov (United States)

    Bastiaansen, John W M; Bovenhuis, Henk; Groenen, Martien A M; Megens, Hendrik-Jan; Mulder, Han A

    2018-04-16

    Genome editing technologies provide new tools for genetic improvement and have the potential to become the next game changer in animal and plant breeding. The aim of this study was to investigate how genome editing in combination with genomic selection can accelerate the introduction of a monogenic trait in a livestock population as compared to genomic selection alone. A breeding population was simulated under genomic selection for a polygenic trait. After reaching Bulmer equilibrium, the selection objective was to increase the allele frequency of a monogenic trait, with or without genome editing, in addition to improving the polygenic trait. Scenarios were compared for time to fixation of the desired allele, selection response for the polygenic trait, and level of inbreeding. The costs, in terms of number of editing procedures, were compared to the benefits of having more animals with the desired phenotype of the monogenic trait. Effects of reduced editing efficiency were investigated. In a population of 20,000 selection candidates per generation, the total number of edited zygotes needed to reach fixation of the desired allele was 22,118, 7072, or 3912 with, no, moderate, or high selection emphasis on the monogenic trait, respectively. Genome editing resulted in up to four-fold faster fixation of the desired allele when efficiency was 100%, while the loss in long-term selection response for the polygenic trait was up to seven-fold less compared to genomic selection alone. With moderate selection emphasis on the monogenic trait, introduction of genome editing led to a four-fold reduction in the total number of animals showing the undesired phenotype before fixation. However, with a currently realistic editing efficiency of 4%, the number of required editing procedures increased by 72% and loss in selection response increased eight-fold compared to 100% efficiency. With low efficiency, loss in selection response was 29% more compared to genomic selection alone

  4. Introductory physics of nuclear medicine. Third edition

    International Nuclear Information System (INIS)

    Chandra, R.

    1987-01-01

    The new third edition includes essential details and many examples and problems taken from the routine practice of nuclear medicine. Basic principles and underlying concepts are explained, although it is assumed that the reader has some current use as a bone densitometer. For resident physicians in nuclear medicine, residents in pathology, radiology, and internal medicine, and students of nuclear medicine technology, the third edition offers a simplified and reliable approach to the physics and basic sciences of nuclear medicine

  5. Shirley Basin Uranium Mill. Environmental report to accompany source material license application

    International Nuclear Information System (INIS)

    1975-12-01

    This document summarizes all of the environmental monitoring conducted by Utah. This Environmental Report consequently supplements and updates the information presented in the Source Material License application of August 18, 1970 and the Final Environmental Statement (FES) of December 1974. Water and air quality, liquid waste management, soil/vegetation monitoring, and reclamation are covered

  6. Education and the American Indian: The Road to Self-Determination since 1928. Third Edition, Revised and Enlarged.

    Science.gov (United States)

    Szasz, Margaret Connell

    First published in 1974, this book was the first full-length study of federal Indian education policy. This revised edition brings the material up to date with the addition of analysis and interpretation of trends and policies that shaped Indian education in the 1980s and 1990s. Chapters are arranged chronologically and cover specific eras such as…

  7. Substantive Editing as a Form of Plagiarism among Postgraduate Students in Australia

    Science.gov (United States)

    Lines, Lisa

    2016-01-01

    In university plagiarism policies, and in the research into plagiarism, one form of collusion remains virtually unacknowledged: substantive editing performed by editors. While almost all Australian universities allow postgraduate students to have their thesis professionally edited, "substantive" editing is prohibited. This article…

  8. Ukrainian baroque editions of the 17th century in the fonds of VNLU

    Directory of Open Access Journals (Sweden)

    Kurganova O.

    2014-01-01

    Full Text Available The article observes the most outstanding Ukrainian baroque editions of the 17th century, deposited in the fonds of V. Vernadsky National Library of Ukraine. The main features of Ukranian literature baroque style that influenced the structure and design of these editions are defined. These features are: allegoric, emblematic, panegyric and theocentric nature of baroque art. Allegory is considered as a structure-forming element of a baroque edition. Emblem presents synthesis of visual and verbal means in baroque artistic book design. Panegyrics become a popular genre of baroque literature, being published as separate editions, as well as a structural part of other editions. Theocentric nature of baroque culture expresses itself mostly in poetic prayers, which function as a common element of preface or afterword to baroque editions. Ukrainian baroque editions are remarkable for their artistic design, which is closely connected to the content of a book.

  9. Shakespeare: A Student's Guide to Basic Reference Sources.

    Science.gov (United States)

    Claener, Anne, Comp.

    Basic and standard reference materials dealing with William Shakespeare are listed in this bibliography. Annotated entries are grouped under the following headings: concordances, dictionaries, encyclopedias and handbooks, and bibliographies. The section on bibliographies is further divided into lists of editions of Shakespeare's work, general…

  10. [CRISPR/CAS9, the King of Genome Editing Tools].

    Science.gov (United States)

    Bannikov, A V; Lavrov, A V

    2017-01-01

    The discovery of CRISPR/Cas9 brought a hope for having an efficient, reliable, and readily available tool for genome editing. CRISPR/Cas9 is certainly easy to use, while its efficiency and reliability remain the focus of studies. The review describes the general principles of the organization and function of Cas nucleases and a number of important issues to be considered while planning genome editing experiments with CRISPR/Cas9. The issues include evaluation of the efficiency and specificity for Cas9, sgRNA selection, Cas9 variants designed artificially, and use of homologous recombination and nonhomologous end joining in DNA editing.

  11. Examining zinc transporting P-type ATPases by genome editing

    DEFF Research Database (Denmark)

    Østerberg, Jeppe Thulin

    with the legal, financial and philosophical implications of using these techniques in crops. One of the feasible uses of genome editing techniques is to repair detrimental mutations that may have occurred in crop plants during domestication in genes controlling traits that could not be selected for. One...... mutants of AtHMA4. The use of genome editing tools holds the potential to generate precise mutations while obtaining a non-transgenic plant within two generations. The creation of such non-transgenic but improved plants by genome editing techniques is discussed here in a series of reviews, along...

  12. RNA editing makes mistakes in plant mitochondria: editing loses sense in transcripts of a rps19 pseudogene and in creating stop codons in coxI and rps3 mRNAs of Oenothera.

    Science.gov (United States)

    Schuster, W; Brennicke, A

    1991-01-01

    An intact gene for the ribosomal protein S19 (rps19) is absent from Oenothera mitochondria. The conserved rps19 reading frame found in the mitochondrial genome is interrupted by a termination codon. This rps19 pseudogene is cotranscribed with the downstream rps3 gene and is edited on both sides of the translational stop. Editing, however, changes the amino acid sequence at positions that were well conserved before editing. Other strange editings create translational stops in open reading frames coding for functional proteins. In coxI and rps3 mRNAs CGA codons are edited to UGA stop codons only five and three codons, respectively, downstream to the initiation codon. These aberrant editings in essential open reading frames and in the rps19 pseudogene appear to have been shifted to these positions from other editing sites. These observations suggest a requirement for a continuous evolutionary constraint on the editing specificities in plant mitochondria. Images PMID:1762921

  13. The CRISPR/Cas genome-editing tool: application in improvement of crops

    Directory of Open Access Journals (Sweden)

    SURENDER eKHATODIA

    2016-04-01

    Full Text Available The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR associated Cas9/sgRNA system is a novel fledgling targeted genome-editing technique from bacterial immune system, which is a cheap, easy and most rapidly adopted genome editing tool transforming to revolutionary paradigm. Cas9 protein is an RNA guided endonuclease utilized for creating targeted double stranded breaks with only a short RNA sequence to confer recognition of the target in animals and plants. Development of genetically edited (GE crops similar to those developed by conventional or mutation breeding using this potential technique makes it a promising and extremely versatile tool for providing sustainable productive agriculture for better feeding of rapidly growing population in changing climate. The emerging areas of research for the genome editing in plants are like, interrogating gene function, rewiring the regulatory signaling networks, sgRNA library for high-throughput loss-of-function screening. In this review, we will discuss the broad applicability of the Cas9 nuclease mediated targeted plant genome editing for development of designer crops. The regulatory uncertainty and social acceptance of plant breeding by Cas9 genome editing have also been discussed. The non-GM designer genetically edited plants could prospect climate resilient and sustainable energy agriculture in coming future for maximizing the yield by combating abiotic and biotic stresses with this new innovative plant breeding technique.

  14. Control of Orphan Sources and Other Radioactive Material in the Metal Recycling and Production Industries. Specific Safety Guide

    International Nuclear Information System (INIS)

    2014-01-01

    Accidents involving orphan sources and other radioactive material in the metal recycling and production industries have resulted in serious radiological accidents as … well as in harmful environmental, social and economic impacts. This Safety Guide provides recommendations, the implementation of which should prevent such accidents and provide confidence that scrap metal and recycled products are safe. Contents: 1. Introduction; 2. Protection of people and the environment; 3. Responsibilities; 4. Monitoring for radioactive material; 5. Response to the discovery of radioactive material; 6. Remediation of contaminated areas; 7. Management of recovered radioactive material; Annex I: Review of events involving radioactive material in the metal recycling and production industries; Annex II: Categorization of radioactive sources; Annex III: Some examples of national and international initiatives

  15. Control of Orphan Sources and Other Radioactive Material in the Metal Recycling and Production Industries. Specific Safety Guide

    International Nuclear Information System (INIS)

    2012-01-01

    Accidents involving orphan sources and other radioactive material in the metal recycling and production industries have resulted in serious radiological accidents as well as in harmful environmental, social and economic impacts. This Safety Guide provides recommendations, the implementation of which should prevent such accidents and provide confidence that scrap metal and recycled products are safe. Contents: 1. Introduction; 2. Protection of people and the environment; 3. Responsibilities; 4. Monitoring for radioactive material; 5. Response to the discovery of radioactive material; 6. Remediation of contaminated areas; 7. Management of recovered radioactive material; Annex I: Review of events involving radioactive material in the metal recycling and production industries; Annex II: Categorization of radioactive sources; Annex III: Some examples of national and international initiatives.

  16. New materials for methane capture from dilute and medium-concentration sources

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J; Maiti, A; Lin, LC; Stolaroff, JK; Smit, B; Aines, RD

    2013-04-16

    Methane (CH4) is an important greenhouse gas, second only to CO2, and is emitted into the atmosphere at different concentrations from a variety of sources. However, unlike CO2, which has a quadrupole moment and can be captured both physically and chemically in a variety of solvents and porous solids, methane is completely non-polar and interacts very weakly with most materials. Thus, methane capture poses a challenge that can only be addressed through extensive material screening and ingenious molecular-level designs. Here we report systematic in silico studies on the methane capture effectiveness of two different materials systems, that is, liquid solvents (including ionic liquids) and nanoporous zeolites. Although none of the liquid solvents appears effective as methane sorbents, systematic screening of over 87,000 zeolite structures led to the discovery of a handful of candidates that have sufficient methane sorption capacity as well as appropriate CH4/CO2 and/or CH4/N-2 selectivity to be technologically promising.

  17. Problems and management of radioactive sources and measures against illicit trafficking of nuclear materials in Bulgaria

    International Nuclear Information System (INIS)

    Strezov, A.

    1998-01-01

    Illicit trafficking of nuclear materials continues to pose a danger to public health and safety and to nuclear non proliferation efforts. The majority of cases so far have involved only small amounts of fissile materials or mainly radioactive sources in Bulgaria. A proper scheme for analysis of seized nuclear materials will be developed based on existing equipment for NDA analysis of nuclear materials supplemented by new system through PHARE project assistance by EU experts. (author)

  18. Melting of a phase change material in a horizontal annulus with discrete heat sources

    Directory of Open Access Journals (Sweden)

    Mirzaei Hooshyar

    2015-01-01

    Full Text Available Phase change materials have found many industrial applications such as cooling of electronic devices and thermal energy storage. This paper investigates numerically the melting process of a phase change material in a two-dimensional horizontal annulus with different arrangements of two discrete heat sources. The sources are positioned on the inner cylinder of the annulus and assumed as constant-temperature boundary conditions. The remaining portion of the inner cylinder wall as well as the outer cylinder wall is considered to be insulated. The emphasis is mainly on the effects of the arrangement of the heat source pair on the fluid flow and heat transfer features. The governing equations are solved on a non-uniform O type mesh using a pressure-based finite volume method with an enthalpy porosity technique to trace the solid and liquid interface. The results are obtained at Ra=104 and presented in terms of streamlines, isotherms, melting phase front, liquid fraction and dimensionless heat flux. It is observed that, depending on the arrangement of heat sources, the liquid fraction increases both linearly and non-linearly with time but will slow down at the end of the melting process. It can also be concluded that proper arrangement of discrete heat sources has the great potential in improving the energy storage system. For instance, the arrangement C3 where the heat sources are located on the bottom part of the inner cylinder wall can expedite the melting process as compared to the other arrangements.

  19. A Minimal Cognitive Model for Translating and Post-editing

    DEFF Research Database (Denmark)

    Schaeffer, Moritz; Carl, Michael

    2017-01-01

    This study investigates the coordination of reading (input) and writing (output) activities in from-scratch translation and post-editing. We segment logged eye movements and keylogging data into minimal units of reading and writing activity and model the process of post-editing and from-scratch t...

  20. Rating of transport and radiation source events. Draft additional guidance for the INES national officers for pilot use and feedback; Echelle de classement des incidents de radioprotection: document d'application du systeme international propose par l'AIEA pour les sources radioactives et les transports

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-09-15

    The International Nuclear Event Scale (INES) is a means for promptly communicating to the public in consistent terms the safety significance of any reported event associated with radioactive material and/or radiation and to any event occurring during the transport of radioactive material. As described in the 2001 Edition of the INES User.s Manual, events are classified on the scale at seven levels: the upper levels (4-7) are termed accidents. and the lower levels (1-3) incidents. Events which have no safety significance are classified below scale at Level 0 and termed deviations. An overview of the principles for the rating under INES together with flow charts summarizing the rating process is provided in Appendix I. The 2001 Edition of the INES User.s Manual provides some guidance for the rating of transport and radiation source events. At the technical meeting held in 2002 the INES National Officers requested the IAEA/NEA Secretariat to prepare additional guidance. Progress was reported at the Technical Meeting of the INES National Officers in March 2004 where preparation of this draft additional guidance was requested for pilot use. This note provides additional guidance on the rating of transport and radiation source events. It is for pilot use and feedback and is broadly consistent with the INES User.s Manual. It provides more detailed information and an expanded approach for the rating based on actual exposure of workers and members of the public. It is designed to be used as a self-standing document with limited need for reference to the INES User Manual. (author)

  1. Macmillan Encyclopedia of Chemistry (edited by Joseph J. Lagowski)

    Science.gov (United States)

    Kauffman, George B.

    1998-11-01

    Macmillan: New York, 1997. Four volumes. Figs., tables. lxxi + 1696 pp. 22.0 x 28.5 cm. $400. ISBN 0-02-897225-2. This latest addition to Macmillan's series of comprehensive core science encyclopedias (previous sets dealt with physics and earth sciences) will be of particular interest to readers of this Journal, for it is edited by longtime Journal of Chemical Education editor Joe Lagowski, assisted by a board of five distinguished associate editors. The attractively priced set offers clear explanations of the phenomena and concepts of chemistry and its materials, whether found in industry, the laboratory, or the natural world. It is intended for a broad spectrum of readers-professionals whose work draws on chemical concepts and knowledge (e.g., material scientists, engineers, health workers, biotechnologists, mathematicians, and computer programmers), science teachers at all levels from kindergarten to high school, high school and college students interested in medicine or the sciences, college and university professors, and laypersons desiring information on practical aspects of chemistry (e.g., household cleaning products, food and food additives, manufactured materials, herbicides, the human body, sweeteners, and animal communication).

  2. Paperwork Plus: Literacy Materials for the Service Industry. Hotel Edition.

    Science.gov (United States)

    Bond, Judith; McGill, Teresa

    The instructional materials are intended for use in teaching vocational English and English literacy to limited-English-speaking personnel in the hotel industry. They are designed for learners at three instructional levels, and address job-specific literacy tasks. An introductory section describes the materials and offers suggestions for…

  3. AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer.

    Science.gov (United States)

    Shigeyasu, Kunitoshi; Okugawa, Yoshinaga; Toden, Shusuke; Miyoshi, Jinsei; Toiyama, Yuji; Nagasaka, Takeshi; Takahashi, Naoki; Kusunoki, Masato; Takayama, Tetsuji; Yamada, Yasuhide; Fujiwara, Toshiyoshi; Chen, Leilei; Goel, Ajay

    2018-06-21

    Adenosine-to-inosine (A-to-I) RNA editing, a process mediated by adenosine deaminases that act on the RNA (ADAR) gene family, is a recently discovered epigenetic modification dysregulated in human cancers. However, the clinical significance and the functional role of RNA editing in colorectal cancer (CRC) remain unclear. We have systematically and comprehensively investigated the significance of the expression status of ADAR1 and of the RNA editing levels of antizyme inhibitor 1 (AZIN1), one of the most frequently edited genes in cancers, in 392 colorectal tissues from multiple independent CRC patient cohorts. Both ADAR1 expression and AZIN1 RNA editing levels were significantly elevated in CRC tissues when compared with corresponding normal mucosa. High levels of AZIN1 RNA editing emerged as a prognostic factor for overall survival and disease-free survival and were an independent risk factor for lymph node and distant metastasis. Furthermore, elevated AZIN1 editing identified high-risk stage II CRC patients. Mechanistically, edited AZIN1 enhances stemness and appears to drive the metastatic processes. We have demonstrated that edited AZIN1 functions as an oncogene and a potential therapeutic target in CRC. Moreover, AZIN1 RNA editing status could be used as a clinically relevant prognostic indicator in CRC patients.

  4. Looking forward to genetically edited fruit crops.

    Science.gov (United States)

    Nagamangala Kanchiswamy, Chidananda; Sargent, Daniel James; Velasco, Riccardo; Maffei, Massimo E; Malnoy, Mickael

    2015-02-01

    The availability of genome sequences for many fruit crops has redefined the boundaries of genetic engineering and genetically modified (GM) crop plants. However commercialization of GM crops is hindered by numerous regulatory and social hurdles. Here, we focus on recently developed genome-editing tools for fruit crop improvement and their importance from the consumer perspective. Challenges and opportunities for the deployment of new genome-editing tools for fruit plants are also discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Application of image editing software for forensic detection of image ...

    African Journals Online (AJOL)

    Application of image editing software for forensic detection of image. ... The image editing software's available today is apt for creating visually compelling and sophisticated fake images, ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  6. Ion source techniques for high-speed processing of material surface by ion beams

    International Nuclear Information System (INIS)

    Ishikawa, Junzo

    1990-01-01

    The present paper discusses some key or candidate techniques for future ion source development and such ion sources developed by the author. Several types of microwave ion sources for producing low charge state ions have been developed in Japan. When a microwave plasma cathode developed by the author is adapted to a Kaufman type ion source, the electron emission currents are found to be 2.5 A for argon gas and 0.5-0.9 A for oxygen gas. An alternative ionization method for metal atoms is strongly required for high-speed processing of material surface by metal-ion beams. Detailed discussion is made of collisional ionization of vaporized atoms, and negative-ion production (secondary negative-ion emission by sputtering). An impregnated electrode type liquid-metal ion source developed by the author, which has a porous tip structure, is described. The negative-ion production efficiency is quite high. The report also presents a neutral and ionized alkaline-metal bombardment type heavy negative-ion source, which consists of a cesium plasma ion source, suppressor, target electrode, negative-ion extraction electrode, and einzel lens. (N.K.)

  7. MP3 audio-editing software for the department of radiology

    International Nuclear Information System (INIS)

    Hong Qingfen; Sun Canhui; Li Ziping; Meng Quanfei; Jiang Li

    2006-01-01

    Objective: To evaluate the MP3 audio-editing software in the daily work in the department of radiology. Methods: The audio content of daily consultation seminar, held in the department of radiology every morning, was recorded and converted into MP3 audio format by a computer integrated recording device. The audio data were edited, archived, and eventually saved in the computer memory storage media, which was experimentally replayed and applied in the research or teaching. Results: MP3 audio-editing was a simple process and convenient for saving and searching the data. The record could be easily replayed. Conclusion: MP3 audio-editing perfectly records and saves the contents of consultation seminar, and has replaced the conventional hand writing notes. It is a valuable tool in both research and teaching in the department. (authors)

  8. Assessment of source material (U and Th) in exploration, mining, processing of zircon sand in Central Kalimantan

    International Nuclear Information System (INIS)

    Dedi Hermawan; Pandu Dewanto; Sudarto

    2011-01-01

    From 2004 to 2008, according to data released by the Commerce Department, the volume of zircon sand and concentrates exports has increased highly. One of many locations in Indonesia that widely available zircon sand is Kalimantan island. For example, Central Kalimantan Province in 2007 to 2008 exports about 51,000 tones up to 79,000 tones of zircon sand annually. The concentration of source material in the zircon sand is important to be known because the presence of natural radioactive U and Th in zircon sand has the potential radiation hazard. Therefore it is necessary to conduct an assessment the potential reserves related to the source material contained in the zircon sand and radiation safety that are applied in the process of mining or processing of zircon sand. In this paper the location of mining and processing of zircon sand is restricted to the province of Central Kalimantan. From the assessment obtained that source material which is carried by zircon sand export form the province of Central Kalimantan have the potential to exceed the limits set by the BAPETEN Chairman Decree No.9 of 2006 About the Implementation of the Additional Protocol to the Accountability System and Control of Nuclear Materials. In terms of compliance with radiation safety, required increased surveillance of K3 during mining, process / processing by the worker, supervisor / supervisors and regional management company to be able the achievement of compliance with the provisions of the management of materials and the safety of radiation sources based on national regulations (BAPETEN) and international. (author)

  9. The players on the European gas market - 2008 edition

    International Nuclear Information System (INIS)

    Lecarpentier, Armelle

    2008-02-01

    In a context of growing dependence on extra-European sources, a growth potential in gas use for power generation and the acceleration of the liberalization process, the 2008 Edition of 'The Players on the European Gas Market' offers a unique detailed review of the positioning of players in both the upstream (production, reserves) and downstream (wholesale and retail supply) sectors of the gas chain. This 140-pages report, includes 55 tables and 29 figures, and presents an in-depth description of the European gas industry by country. The Survey 'The Players on the European Gas Market' provides: - The analysis of new upstream areas and production growth prospects, - Company rankings in terms of reserve and production volumes, - The complete overview of the whole European gas market (market characteristics, supply sources, consuming outlets, effective competition), - Strategies and key facts of the wholesale suppliers to Europe, - An in-depth review of national market structures, - The detailed positioning and analysis of national market power of the numerous companies involved in gas supply

  10. Materiality in a Practice-Based Approach

    Science.gov (United States)

    Svabo, Connie

    2009-01-01

    Purpose: The paper aims to provide an overview of the vocabulary for materiality which is used by practice-based approaches to organizational knowing. Design/methodology/approach: The overview is theoretically generated and is based on the anthology Knowing in Organizations: A Practice-based Approach edited by Nicolini, Gherardi and Yanow. The…

  11. Security in the transport of radioactive material: Implementing guide. Spanish edition

    International Nuclear Information System (INIS)

    2013-01-01

    This guide provides States with guidance in implementing, maintaining or enhancing a nuclear security regime to protect radioactive material (including nuclear material) in transport against theft, sabotage or other malicious acts that could, if successful, have unacceptable radiological consequences. From a security point of view, a threshold is defined for determining which packages or types of radioactive material need to be protected beyond prudent management practice. Minimizing the likelihood of theft or sabotage of radioactive material in transport is accomplished by a combination of measures to deter, detect, delay and respond to such acts. These measures are complemented by other measures to recover stolen material and to mitigate possible consequences, in order to further reduce the risks

  12. Security in the Transport of Radioactive Material. Implementing Guide (French Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    This guide provides States with guidance in implementing, maintaining or enhancing a nuclear security regime to protect radioactive material (including nuclear material) in transport against theft, sabotage or other malicious acts that could, if successful, have unacceptable radiological consequences. From a security point of view, a threshold is defined for determining which packages or types of radioactive material need to be protected beyond prudent management practice. Minimizing the likelihood of theft or sabotage of radioactive material in transport is accomplished by a combination of measures to deter, detect, delay and respond to such acts. These measures are complemented by other measures to recover stolen material and to mitigate possible consequences, in order to further reduce the risks.

  13. Security in the Transport of Radioactive Material. Implementing Guide (Chinese Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    This guide provides States with guidance in implementing, maintaining or enhancing a nuclear security regime to protect radioactive material (including nuclear material) in transport against theft, sabotage or other malicious acts that could, if successful, have unacceptable radiological consequences. From a security point of view, a threshold is defined for determining which packages or types of radioactive material need to be protected beyond prudent management practice. Minimizing the likelihood of theft or sabotage of radioactive material in transport is accomplished by a combination of measures to deter, detect, delay and respond to such acts. These measures are complemented by other measures to recover stolen material and to mitigate possible consequences, in order to further reduce the risks.

  14. A Fusion Neutron Source for Materials and Subcomponent Development and Qualification

    Science.gov (United States)

    Simonen, Thomas

    2010-11-01

    The magnetic-mirror based Gas Dynamic Trap (GDT) device in Novosibirsk Russia is developing the physics basis for a compact DT Neutron Source (DTNS) for fusion materials and subcomponent development as well as a driver for a fusion-fission driver for nuclear waste burn-up. The efficiency of this concept depends on electron temperature. This paper describes past experimental results as well as methods and prospects to further increase the electron temperature.

  15. Small RNA and A-to-I Editing in Autism Spectrum Disorders

    Science.gov (United States)

    Eran, Alal

    One in every 88 children is diagnosed with Autism Spectrum Disorders (ASDs), a set of neurodevelopmental conditions characterized by social impairments, communication deficits, and repetitive behavior. ASDs have a substantial genetic component, but the specific cause of most cases remains unknown. Understanding gene-environment interactions underlying ASD is essential for improving early diagnosis and identifying critical targets for intervention and prevention. Towards this goal, we surveyed adenosine-to-inosine (A-to-I) RNA editing in autistic brains. A-to-I editing is an epigenetic mechanism that fine-tunes synaptic function in response to environmental stimuli, shown to modulate complex behavior in animals. We used ultradeep sequencing to quantify A-to-I receding of candidate synaptic genes in postmortem cerebella from individuals with ASD and neurotypical controls. We found unexpectedly wide distributions of human A-to-I editing levels, whose extremes were consistently populated by individuals with ASD. We correlated A-to-I editing with isoform usage, identified clusters of correlated sites, and examined differential editing patterns. Importantly, we found that individuals with ASD commonly use a dysfunctional form of the editing enzyme ADARB1. We next profiled small RNAs thought to regulate A-to-I editing, which originate from one of the most commonly altered loci in ASD, 15q11. Deep targeted sequencing of SNORD115 and SNORD116 transcripts enabled their high-resolution detection in human brains, and revealed a strong gender bias underlying their expression. The consistent 2-fold upregulation of 15q11 small RNAs in male vs. female cerebella could be important in delineating the role of this locus in ASD, a male dominant disorder. Overall, these studies provide an accurate population-level view of small RNA and A-to-I editing in human cerebella, and suggest that A-to-I editing of synaptic genes may be informative for assessing the epigenetic risk for autism

  16. A compendium of fossil marine animal families, 2nd edition

    Science.gov (United States)

    Sepkoski, J. J. Jr; Sepkoski JJ, J. r. (Principal Investigator)

    1992-01-01

    A comprehensive listing of 4075 taxonomic families of marine animals known from the fossil record is presented. This listing covers invertebrates, vertebrates, and animal-like protists, gives time intervals of apparent origination and extinction, and provides literature sources for these data. The time intervals are mostly 81 internationally recognized stratigraphic stages; more than half of the data are resolved to one of 145 substage divisions, providing more highly resolved data for studies of taxic macroevolution. Families are classified by order, class, and phylum, reflecting current classifications in the published literature. This compendium is a new edition of the 1982 publication, correcting errors and presenting greater stratigraphic resolution and more current ideas about acceptable families and their classification.

  17. MANAJEMEN EDITING POST PRODUCTION PROGRAM CURRENT AFFAIR DI TVONE

    Directory of Open Access Journals (Sweden)

    Ridho Azlam Ambo Asse

    2016-11-01

    Full Text Available Management is the art of completing the work through others. In an organization there are various components that are structured and coordinated in the movement toward shared vision and mission. Management is looking for that component to move under coordination, pressure, and problems that hit. Editing management, especially for the current affair type program, has a special purpose. Not just the speed of productivity that is based on the ability of individual editors. This research is done to know the process of stage editor in work. The process of managing files, data management, human resources, tools, facilities, scheduling, until the pattern of editing stage in one of the national media industry. This study concludes that the current affair program management editing system based on the concept of planning, organizing, implementation, supervision, and productivity management is done by Top Down method from top to bottom in the management of currenf affair tvOne editing program. What gets from above during a pre-production meeting of a program. Then coordinate with the supervisor and then delegate down to be implemented according to the agreed plan and in accordance with the duties and functions of both the production team and the editor.   Manajemen merupakan seni menyelesaikan pekerjaan melalui orang lain. Dalam sebuah organisasi terdapat berbagai macam komponen yang terstruktur dan terkordinasi dalam gerakan menuju visi dan misi bersama. Manajemen ialah mencari agar komponen tersebut dapat bergerak dibawah koordinasi, tekanan, dan masalah yang menerpa. Manajemen editing khususnya untuk program berjenis current affair, memiliki tujuan khusus. Tidak sekedar kecepatan produktifitas yang didasarkan pada kemampuan individu editor. Penelitian yang dilakukan ini untuk mengetahui proses tahapan editor dalam bekerja. Proses mengelola file, pengelolaan data, sumber daya manusia, alat, fasilitas, penjadwalan, hingga pola tahapan editing pada salah

  18. Catalog of NBS standard reference materials, 1975--76 edition. Special pub

    International Nuclear Information System (INIS)

    Seward, R.W.

    1975-06-01

    This Catalog lists and describes the Standard Reference Materials (SRM's), Research Materials (RM's), and General Materials (GM's) currently distributed by the National Bureau of Standards, as well as many of the materials currently in preparation. SRM's are used to calibrate measurement systems and to provide a central basis for uniformity and accuracy of measurement. The unit and quantity, the type, and the certified characterization are listed for each SRM, as well as directions for ordering. The RM's are not certified, but are issued to meet the needs of scientists engaged in materials research. RM's are issued with a 'Report of Investigation', the sole authority of which is the author of the report. The GM's are standardized by some agency other than NBS. NBS acts only as a distribution point and does not participate in the standardization of these materials. Announcements of new and renewal SRM's, RM's and GM's are made in the semi-annual supplements of this Catalog, SRM Price List, and in scientific and trade journals

  19. TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites.

    Science.gov (United States)

    Ammerman, Michelle L; Presnyak, Vladimir; Fisk, John C; Foda, Bardees M; Read, Laurie K

    2010-11-01

    TbRGG2 is an essential kinetoplastid RNA editing accessory factor that acts specifically on pan-edited RNAs. To understand the mechanism of TbRGG2 action, we undertook an in-depth analysis of edited RNA populations in TbRGG2 knockdown cells and an in vitro examination of the biochemical activities of the protein. We demonstrate that TbRGG2 down-regulation more severely impacts editing at the 5' ends of pan-edited RNAs than at their 3' ends. The initiation of editing is reduced to some extent in TbRGG2 knockdown cells. In addition, TbRGG2 plays a post-initiation role as editing becomes stalled in TbRGG2-depleted cells, resulting in an overall decrease in the 3' to 5' progression of editing. Detailed analyses of edited RNAs from wild-type and TbRGG2-depleted cells reveal that TbRGG2 facilitates progression of editing past intrinsic pause sites that often correspond to the 3' ends of cognate guide RNAs (gRNAs). In addition, noncanonically edited junction regions are either absent or significantly shortened in TbRGG2-depleted cells, consistent with impaired gRNA transitions. Sequence analysis further suggests that TbRGG2 facilitates complete utilization of certain gRNAs. In vitro RNA annealing and in vivo RNA unwinding assays demonstrate that TbRGG2 can modulate RNA-RNA interactions. Collectively, these data are consistent with a model in which TbRGG2 facilitates initiation and 3' to 5' progression of editing through its ability to affect gRNA utilization, both during the transition between specific gRNAs and during usage of certain gRNAs.

  20. Traditional uses of American plant species from the 1st edition of Brazilian Official Pharmacopoeia

    Directory of Open Access Journals (Sweden)

    Maria G. L. Brandão

    Full Text Available The first edition of the Brazilian Official Pharmacopoeia (FBRAS, published in 1929, is a rich source of information about American medicinal plants, since it lists species used in both traditional and conventional medicine. In this study, we have performed a survey of the traditional uses of plants described in eighty-seven Monographs from the FBRAS in twenty bibliographies written from the 19th century to the 1970s. Eighty-six different traditional uses are described in three or more books; some of them were cited in ten or more books, illustrating their widespread use and importance in medicine. The species from the first edition of the FBRAS have a long tradition of medical utility, which is confirmed by historical records. In surveying these medically relevant species, we hope to encourage policy makers and the scientific public as a whole to engage in a strong debate in an attempt to improve and facilitate the pharmacological study of these species.