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Sample records for sorbus aria sorbus

  1. Sorbus aucuparia and Sorbus aria as a Source of Antioxidant Phenolics, Tocopherols, and Pigments.

    OpenAIRE

    Šavikin, Katarina P.; Zdunić, Gordana M.; Krstić-Milošević, Dijana B.; Šircelj, Helena J.; Stešević, Danijela D.; Pljevljakušić, Dejan S.

    2017-01-01

    Due to its nutritive and medicinal properties, berries of some Sorbus species are used for the preparation of jams and jelly as well as in traditional medicine. On the other hand, their chemical composition is not much studied especially of those grown in Balkan Peninsula. We have analyzed individual phenolics, tocopherols, carotenoids and chlorophylls using HPLC in berries from Sorbus aucuparia and Sorbus aria collected in different localities in Serbia and Montenegro together with the amoun...

  2. Sorbus aucuparia and Sorbus aria as a Source of Antioxidant Phenolics, Tocopherols, and Pigments.

    Science.gov (United States)

    Šavikin, Katarina P; Zdunić, Gordana M; Krstić-Milošević, Dijana B; Šircelj, Helena J; Stešević, Danijela D; Pljevljakušić, Dejan S

    2017-12-01

    Due to its nutritive and medicinal properties, berries of some Sorbus species are used for the preparation of jams and jelly as well as in traditional medicine. On the other hand, their chemical composition is not much studied especially of those grown in Balkan Peninsula. We have analyzed individual phenolics, tocopherols, carotenoids and chlorophylls using HPLC in berries from Sorbus aucuparia and Sorbus aria collected in different localities in Serbia and Montenegro together with the amounts of total phenolics and proanthocyanidins as well as their radical scavenging activity against DPPH radical. Berries of S. aucuparia were richer source of polyphenolics in comparision with S. aria and, regardless the species and locality, caffeoylquinic acids such as neochlorogenic and chlorogenic acid were the most abundant compounds. Among analyzed tocopherols the most abundant in all samples was α-tocopherol (0.48 - 19.85 μg/g dw) as it was β-carotene among carotenoids (mean concentration of 0.98 μg/g dw in S. aucuparia and 0.40 μg/g dw in S. aria, respectively). Correlation between total phenolics and DPPH radical scavenging activity was noticed. Our study represents comprehensive report on chemical composition of S. aucuparia and S. aria which could contribute to a better understanding of their quality. © 2017 Wiley-VHCA AG, Zurich, Switzerland.

  3. Phytochemical and antioxidant profiles of leaves from different Sorbus L. species.

    Science.gov (United States)

    Raudonė, Lina; Raudonis, Raimondas; Gaivelytė, Kristina; Pukalskas, Audrius; Viškelis, Pranas; Venskutonis, Petras Rimantas; Janulis, Valdimaras

    2015-02-01

    Leaves of Sorbus L. have been used in various traditional medicine systems. Phenolic compounds determine the main pharmacological effects of Sorbus L. In this study, phytochemical and antioxidant profiles of Sorbus anglica, Sorbus aria, Sorbus arranensis, Sorbus aucuparia, Sorbus austriaca, Sorbus caucasica, Sorbus commixta, Sorbus discolor, Sorbus gracilis, Sorbus hostii, Sorbus semi-incisa and Sorbus tianschanica were determined. Twenty four constituents were identified in Sorbus L. species using ultra high performance liquid chromatography coupled to quadruple and time-of-flight mass spectrometers. Post-column FRAP assay identified compounds with reducing activity and revealed significantly greatest total antioxidant activity of 175.30 μmol TE/g DW, 169.20 μmol TE/g DW and 148.11 μmol TE/g DW in S. commixta, S. discolor and S. gracilis leaf samples, respectively, with neochlorogenic and chlorogenic acids being most significant contributors. Characteristic fingerprints of phytochemical and antioxidant profiles could be applied for the quality evaluation of various raw materials of Sorbus L. species.

  4. A Chalcone Glycoside from the Fruits of Sorbus commixta Hedl.

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    Kyu Yun Chai

    2009-12-01

    Full Text Available Sorbus commixta Hedl. (Rosaceae has been traditionally used in oriental countries for the treatment of asthma and other bronchial disorders. In this study, a chalcone glycoside was isolated from the ethyl acetate extract of the fruits of this plant. The compound was identified as neosakuranin based on the spectroscopic analysis and comparion with literature data. This is the first report of isolation of neosakuranin from Sorbus commixta.

  5. Spatial structure of a natural mixed topodeme of subalpine Sorbus taxa

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    Dušan Gömöry

    2011-01-01

    Full Text Available Spatial distribution and genetic variation of a population of Sorbus chamaemespilus (L. Crantz and putative hybrids between S. chamaemespilus, S. aria and S. aucuparia growing in the nature reserve Skalnä Alpa (central Slovakia were studied. The analysis of spatial patterns using Ripley's K-function revealed a significant clustering of the adults of both S. chamaemespilus and hybrid taxa at distances up to ~15 m and a strong affinity between both taxonomical groups, indicating similar ecological requirements. Bivariate point-pattern analysis considering cardinal direction showed that juvenile individuals of S. chamaemespilus are clustered around the adults up to the distance of ~2 m, whereas in hybrid taxa with larger and more dense crowns, juveniles are clustered at distances more than ~3 m from the adults. The analysis of genetic variation in a subset of adult shrubs using 4 nuclear microsatellite loci revealed that unlike expected, there was no variation in S. chamaemespilus but several genotypes were found in the group of hybrid taxa. Implications for the reproduction system and conservation of the investigated taxa are discussed.

  6. Isolation and recrystallization of epicuticular waxes from Sorbus and Cotoneaster leaves

    OpenAIRE

    Ganeva Tsveta; Stefanova Miroslava; Koleva Dimitrina; Ruiz Segundo Ríos

    2015-01-01

    Wax morphology and chemical composition are widely accepted to be important for the protective properties of the leaf’s surface and also valuable characteristics in plant systematics. The leaves of Sorbus domestica L. and Cotoneaster granatensis Boiss., species of two large genera with intricate taxonomy referred to subtribe Pyrinae, Rosaceae (formerly subfamily Maloideae), were studied by scanning electron microscope (SEM) and performing different methods of wax isola...

  7. Competitive success of southern populations of Betula pendula and Sorbus aucuparia under simulated southern climate experiment in the subarctic.

    Science.gov (United States)

    Taulavuori, Kari; Taulavuori, Erja; Saravesi, Karita; Jylänki, Tanja; Kainulainen, Aila; Pajala, Jonna; Markkola, Annamari; Suominen, Otso; Saikkonen, Kari

    2017-06-01

    Global warming has been commonly accepted to facilitate species' range shifts across latitudes. Cross-latitudinal transplantations support this; many tree species can well adapt to new geographical areas. However, these studies fail to capture species' adaptations to new light environment because the experiments were not designed to explicitly separate species' responses to light and temperature. Here we tested reaction norms of tree seedlings in reciprocal transplantations 1,000 km apart from each other at two latitudes (60°N and 69°N). In contrast to past studies, we exposed our experimental plants to same temperature in both sites (temperature of 60°N growing site is recorded to adjust temperature of 69°N site in real time via Internet connection) while light environment (photoperiod, light quality) remained ambient. Shoot elongation and autumn coloration were studied in seedlings of two deciduous trees ( Betula pendula and Sorbus aucuparia ), which were expected to respond differently to day length. Sorbus as a member of Rosaceae family was assumed to be indifferent to photoperiod, while Betula responds strongly to day length. We hypothesized that (1) southern and northern populations of both species perform differently; (2) southern populations perform better in both sites; (3) autumn phenology of southern populations may delay in the northern site; (4) and Sorbus aucuparia is less dependent on light environment. According to the hypotheses, shoot elongation of northern population was inherently low in both species. An evolutionary consequence of this may be a competitive success of southern populations under warming climate. Southern population of B. pendula was delayed in autumn coloration, but not in growth cessation. Sorbus aucuparia was less responsive to light environment. The results suggest that light provides selection pressure in range shifts, but the response is species dependent.

  8. The Impact of Different Water Regime on Chlorophyll Fluorescence of Pyrus pyraster L. and Sorbus domestica L

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    Viera Šajbidorová

    2015-01-01

    Full Text Available The water deficit is considered to be significant cause of photosynthesis defects. Measuring of chlorophyll fluorescence is one of the methods revealing defects in the photosynthetic apparatus. The experiment was established with two woody plant (Pyrus pyraster L. and Sorbus domestica L. cultivated in two different regimes of the substrate saturation. The measurement of the modulated fluorescence of chlorophyll a was done by FMS1 fluorometer during three-week period between June and September (2012 and 2013. There were analysed selected parameters of chlorophyll fluorescence: Fv/Fm – maximum quantum efficiency of PSII, ΦPSII – effective quantum yield of PSII and RFD – chlorophyll fluorescence decrease ratio. According to the obtained results, Pyrus pyraster has probably higher potential for adaptation to water deficiency. There were recorded the significant decreases mainly in the values of parameter RFD and ΦPSII for Sorbus domestica within duration of experiment with different water regime in both growing seasons 2012 and 2013. The results document a weak sensitivity of the parameter Fv/Fm on changes in the amount of available water in the substrate in both taxa.

  9. Phytogeographic and genetic variation in Sorbus, a traditional antidiabetic medicine—adaptation in action in both a plant and a discipline

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    Anna Bailie

    2016-11-01

    Full Text Available Mountain ash (Sorbus decora and S. americana is used by the Cree Nation of the James Bay region of Quebec (Eeyou Istchee as traditional medicine. Its potential as an antidiabetic medicine is thought to vary across its geographical range, yet little is known about the factors that affect its antioxidant capacity. Here, we examined metabolite gene expression in relation to antioxidant activity, linking phytochemistry and medicinal potential. Samples of leaf and bark from S. decora and S. americana were collected from 20 populations at four different latitudes. Two genes known to produce antidiabetic substances, flavonol synthase and squalene synthase, were analyzed using quantitative real time PCR. Gene expression was significantly higher for flavonol synthase compared to squalene synthase and increased in the most Northern latitude. Corresponding differences observed in the antioxidant capacity of ethanolic extracts from the bark of Sorbus spp. confirm that plants at higher latitudes increase production of stress-induced secondary metabolites and support Aboriginal perceptions of their higher medicinal potential. Modern genetic techniques such as quantitative real time PCR offer unprecedented resolution to substantiate and scrutinise Aboriginal medicinal plant perception. Furthermore, it offers valuable insights into how environmental stress can trigger an adaptive response resulting in the accumulation of secondary metabolites with human medicinal properties.

  10. Arum-type of arbuscular mycorrhizae, dark septate endophytes and Olpidium spp. in fine roots of container-grown seedlings of Sorbus torminalis (Rosaceae

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    Roman M. Bzdyk

    2016-06-01

    Full Text Available The aim of this study was to determine the mycorrhizal status of nursery seedlings of the wild service tree (Sorbus torminalis, which belongs to the Rosaceae family. Its mycorrhizal associations are still fragmentarily known, and data from the few existing studies indicate that it forms ectomycorrhizal symbiosis (ECM. We analyzed the degree of mycorrhizal colonization of thirty 2-year-old container-grown S. torminalis nursery seedlings, which belonged to three single-tree progenies. The roots were dominated by arbuscular mycorrhizae (AM, with the morphology of the Arum-type containing arbuscules, vesicles and hyphae; however, no ECM structures were found. The degree of root colonization of the analyzed seedlings by AM fungi was 83.6% and did not differ significantly between the three single-tree progenies. In addition to AM, structures of dark septate endophytes (0.7% and sporangia of Olpidium spp. (1.1% were found in wild service tree roots. In agreement with previous studies, we confirmed arbuscular mycorrhizae for S. torminalis. Moreover, this is the first report that roots of this Sorbus species show the Arum-type morphology of AM and are associated with Olpidium species.

  11. S-allele diversity in Sorbus aucuparia and Crataegus monogyna (Rosaceae: Maloideae).

    Science.gov (United States)

    Raspé, O; Kohn, J R

    2002-06-01

    RT-PCR was used to obtain the first estimates from natural populations of allelic diversity at the RNase-based gametophytic self-incompatibility locus in the Rosaceae. A total of 20 alleles were retrieved from 20 Sorbus aucuparia individuals, whereas 17 alleles were found in 13 Crataegus monogyna samples. Estimates of population-level allele numbers fall within the range observed in the Solanaceae, the only other family with RNase-based incompatibility for which estimates are available. The nucleotide diversity of S-allele sequences was found to be much lower in the two Rosaceae species as compared with the Solanaceae. This was not due to a lower sequence divergence among most closely related alleles. Rather, it is the depth of the entire genealogy that differs markedly in the two families, with Rosaceae S-alleles exhibiting more recent apparent coalescence. We also investigated patterns of selection at the molecular level by comparing nucleotide diversity at synonymous and nonsynonymous sites. Stabilizing selection was inferred for the 5' region of the molecule, while evidence of diversifying selection was present elsewhere.

  12. Rapid production of trees. [Acer platanoides, Fraxinus excelsior, Quercus robus, Sorbus, Picea, and Abies spp. , Betula verrucose, Populus trichocarpa

    Energy Technology Data Exchange (ETDEWEB)

    Haarjorg, A.

    1976-01-01

    Seedlings of Acer platanoides approximately 2 m tall were produced in southern Norway in one year by seed stratification indoors. Similar results were obtained with Fraxinus excelsior, Quercus robus and Sorbus spp. Trails were also carried out with Betula verrucose (B. pendula), Populus trichocarpa, Picea spp., Abies spp., and other conifers. In all trials growth was increased when plants were raised in a plastic house, and depended on the time that Spring growth was started or whether supplementary light was given and also depended on the seed strain. For northern and high altitude strains it was important to maintain critical day length.

  13. EFFICIENCY OF REAL-TIME PCR FOR 18S rRNA AMPLIFICATION OF SORBUS DOMESTICA, L.

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    Petronela Poláčeková

    2012-10-01

    Full Text Available Normal 0 21 false false false SK X-NONE X-NONE Nowadays, the awareness is given more and more to underutilized and  unusual fruits. One of them is Sorbus domestica, L. not only as an endangered species, but as well as a promising and economically usable crop. The work was aimed for finding a total genomic DNA isolating methods from fresh plant material and confirmation of the optimized method by the detection of 18S rRNA gene using real-time PCR. Two commercial isolation kits were tested -  Invisorb® Spin Plant Mini Kit and Wizard ® Genomic DNA. Higher purity and yield of DNA isolation kit showed Invisorb kit. The effective and pure PCR amplification was confirmed for Invisorb, too when 20 ng undiluted DNA at annealing temperature of 64.5 °C.doi:10.5219/203

  14. Characterisation of Sorbus domestica L. Bark, Fruits and Seeds: Nutrient Composition and Antioxidant Activity

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    Boris Majić

    2015-01-01

    Full Text Available The aim of this work is to assess the nutritional value of service tree (Sorbus domestica L. bark, fruit exocarp and mesocarp, and seeds by establishing the levels of macro- and microelements, total phenolics, flavonoids and tannins. Our results revealed that all of the tested service tree samples were rich in potassium. Bark was the best source of calcium and zinc, while seeds were the best source of magnesium. Compared to the bark and seeds, fruit exocarp and mesocarp contained significantly lower amounts of these three elements. Immature exocarp and bark contained the highest amounts of total phenolics and showed the highest antioxidant activity. Maturation significantly decreased the amount of total phenolics in fruits, as well as the antioxidant activity of total phenolics and total tannins from exocarp, but not from mesocarp. Exocarp was the richest in total flavonoids. Based on the obtained data, we have concluded that the under-utilised species S. domestica L. could serve as an important source of mineral elements and antioxidants in the human diet.

  15. In Vivo Anti-Diabetic Activity of the Ethanolic Crude Extract of Sorbus decora C.K.Schneid. (Rosacea: A Medicinal Plant Used by Canadian James Bay Cree Nations to Treat Symptoms Related to Diabetes

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    Rose Vianna

    2011-01-01

    Full Text Available A number of potential anti-diabetic plants were identified through an ethnobotanical survey of the traditional pharmacopeia of the Cree of Eeyou Istchee (CEI—Northeastern Canada used against symptoms of diabetes and their biological activity assessed by in vitro bioassays. Among these, Sorbus decora C.K.Schneid. (Rosacea ranked highly and increased the transport of glucose in skeletal muscle cells in culture. The present study thus aimed at confirming the antidiabetic potential of S. decora in in vivo models of insulin resistance and diabetes, notably the streptozotocin Type 1 diabetic rat (STZ, the genetic KK-Ay Type 2 diabetic mouse and the rat rendered insulin resistant with 10% glucose water consumption for 6 weeks. Sorbus decora ethanolic crude extract (SDEE was administered orally (200 mg kg-1 and compared to metformin (150 or 500 mg kg-1. The intragastric (i.g. gavage of SDEE transiently decreased glycemia in STZ rats in a bi-phasic manner but the effect was cumulative over several days. In KK-Ay mice, SDEE incorporated in food (0.12% decreased glycemia by 15% within 1 week as compared to vehicle controls. In pre-diabetic insulin-resistant rats, SDEE fed daily by i.g. gavage for 2 weeks significantly decreased the slight hyperglycemia and hyperinsulinemia, without affecting sugar water intake. Using the HOMA insulin resistance parameter, the effect of SDEE was equivalent to that of metformin. In conclusion, the ethanolic crude extract of S. decora demonstrates both anti-hyperglycemic and insulin-sensitizing activity in vivo, thereby confirming anti-diabetic potential and validating CEI traditional medicine.

  16. Tree species composition affects the abundance of rowan (Sorbus aucuparia L.) in urban forests in Finland.

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    Hamberg, Leena; Lehvävirta, Susanna; Kotze, D Johan; Heikkinen, Juha

    2015-03-15

    Recent studies have shown a considerable increase in the abundance of rowan (Sorbus aucuparia) saplings in urban forests in Finland, yet the reasons for this increase are not well understood. Here we investigated whether canopy cover or tree species composition, i.e., the basal areas of different tree species in Norway spruce dominated urban forests, affects the abundances of rowan seedlings, saplings and trees. Altogether 24 urban forest patches were investigated. We sampled the number of rowan and other saplings, and calculated the basal areas of trees. We showed that rowan abundance was affected by tree species composition. The basal area of rowan trees (≥ 5 cm in diameter at breast height, dbh) decreased with increasing basal area of Norway spruce, while the cover of rowan seedlings increased with an increase in Norway spruce basal area. However, a decrease in the abundance of birch (Betula pendula) and an increase in the broad-leaved tree group (Acer platanoides, Alnus glutinosa, Alnus incana, Amelanchier spicata, Prunus padus, Quercus robur, Rhamnus frangula and Salix caprea) coincided with a decreasing number of rowans. Furthermore, rowan saplings were scarce in the vicinity of mature rowan trees. Although it seems that tree species composition has an effect on rowan, the relationship between rowan saplings and mature trees is complex, and therefore we conclude that regulating tree species composition is not an easy way to keep rowan thickets under control in urban forests in Finland. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Taxonomic revision of Sorbus subgenus Aria occurring in the Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Lepší, M.; Lepší, P.; Koutecký, P.; Bílá, J.; Vít, Petr

    2015-01-01

    Roč. 87, č. 2 (2015), s. 109-162 ISSN 0032-7786 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : apomixis * DAPI flow cytometry * hybridization Subject RIV: EF - Botanics Impact factor: 2.711, year: 2015

  18. Role of planting stock size and fertilizing in initial growth performance of rowan (Sorbus aucuparia L. reforestation in a mountain frost hollow

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    Ivan Kuneš

    2014-08-01

    Full Text Available The aim of study: (1 to compare the survival rate, growth performance and nutrition of large and common-sized planting stock of rowan (Sorbus aucuparia L. on a frost-exposed site and (2 to assess whether fertilizing had any effect on the plantations.Area of study: The Jizera Mts., an area heavily disturbed by air pollution situated on the Czech-Polish border close to GermanyMaterials and methods: Two types of planting stock were tested in a mountain frost hollow on an acidic mountain humic podsol: (a the bare-rooted saplings 131–140 cm tall and (b common-sized containerized transplants 26–35 cm. One half of the saplings and common-sized transplants were left untreated and the other half were fertilized with a low dose (30 g per tree of a slow release fertilizer based on methylene urea and potassium magnesium phosphate. Growth performance and nutrition of plantations were investigated.Main results: Due to serious deformations and stem breakages inflicted by snow and frost, the prospects of common-sized transplants seem much worse than those of saplings. The height growth of saplings was significantly more rapid than that of common-sized transplants. As for growth, neither the saplings nor common-sized transplants did significantly respond to fertilizing. The effects of fertilizing on nutrition of rowans were unconvincing. The extreme temperature events during growth seasons and snow deformations in winters might be the decisive factors influencing growth performance of rowans under referred conditions.Research highlights: On the frost-exposed sites, the height of taller saplings might partly compensate for a missing shelter of forest stand since the terminal leaders are above ground-frost zone.Key words: mountain ash; sapling; common-sized transplants; nutritional status; temperature.Abbreviations: CS – Control Saplings; CT – Control Transplants; FS – Fertilized Saplings; FT – Fertilized Transplants

  19. High molecular diversity in the true service tree (Sorbus domestica) despite rareness: data from Europe with special reference to the Austrian occurrence.

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    George, Jan-Peter; Konrad, Heino; Collin, Eric; Thevenet, Jean; Ballian, Dalibor; Idzojtic, Marilena; Kamm, Urs; Zhelev, Peter; Geburek, Thomas

    2015-06-01

    Sorbus domestica (Rosaceae) is one of the rarest deciduous tree species in Europe and is characterized by a scattered distribution. To date, no large-scale geographic studies on population genetics have been carried out. Therefore, the aims of this study were to infer levels of molecular diversity across the major part of the European distribution of S. domestica and to determine its population differentiation and structure. In addition, spatial genetic structure was examined together with the patterns of historic and recent gene flow between two adjacent populations. Leaf or cambium samples were collected from 17 populations covering major parts of the European native range from north-west France to south-east Bulgaria. Seven nuclear microsatellites and one chloroplast minisatellite were examined and analysed using a variety of methods. Allelic richness was unexpectedly high for both markers within populations (mean per locus: 3·868 for nSSR and 1·647 for chloroplast minisatellite). Moreover, there was no evidence of inbreeding (mean Fis = -0·047). The Italian Peninsula was characterized as a geographic region with comparatively high genetic diversity for both genomes. Overall population differentiation was moderate (FST = 0·138) and it was clear that populations formed three groups in Europe, namely France, Mediterranean/Balkan and Austria. Historic gene flow between two local Austrian populations was high and asymmetric, while recent gene flow seemed to be disrupted. It is concluded that molecular mechanisms such as self-incompatibility and high gene flow distances are responsible for the observed level of allelic richness as well as for population differentiation. However, human influence could have contributed to the present genetic pattern, especially in the Mediterranean region. Comparison of historic and recent gene flow may mirror the progress of habitat fragmentation in eastern Austria. © The Author 2015. Published by Oxford University Press

  20. Timing and duration of autumn leaf development in Sweden

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    Bolmgren, Kjell

    2014-05-01

    The growing season is changing in both ends and autumn phases seem to be responding in more diverse ways than spring events. Indeed, we know little about autumn leaf phenological strategies and how they are correlated with fitness components or ecosystem properties, and how they vary between species and over bioclimatic gradients. In this study more than 10 000 students were involved in observing autumn leaf development at 378 sites all over Sweden (55-68°N). They followed an image based observation protocol classifying autumn leaf development into five levels, from summer green (level 0) to 100% autumn leaf colored (level 4) canopy. In total, they submitted almost 12 000 observations between August 9 and November 15. 75% of the observations were made on the common species of Populus tremula, Betula pendula/pubescens and Sorbus aucuparia. The expected (negative) correlation between latitude and start of leaf senescence (level 2) was found in Populus and Betula, but not in Sorbus. The duration of the leaf senescence period, defined as the period between 1/3 (level 2) and 100% (level 4) of the canopy autumn leaf colored, was negatively correlated with latitude in Populus and Betula, but not in Sorbus. There was also a strong (negative) correlation of the start (level 2) and the duration of the leaf senescence in the early senescing Sorbus and Betula, while this effect was weaker in the late senescing Populus.

  1. Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab.

    Science.gov (United States)

    Liu, Enchi; Wang, Dai; Sperling, Reisa; Salloway, Stephen; Fox, Nick C; Blennow, Kaj; Scheltens, Philip; Schmidt, Mark E; Streffer, Johannes; Novak, Gerald; Einstein, Steve; Booth, Kevin; Ketter, Nzeera; Brashear, H Robert

    2018-03-06

    To evaluate whether amyloid-related imaging abnormalities with edema/effusion (ARIA-E) observed in bapineuzumab clinical trials was associated with specific biomarker patterns. Bapineuzumab, an anti-β-amyloid monoclonal antibody, was evaluated in patients with mild to moderate Alzheimer disease. Amyloid PET imaging, CSF biomarkers, or volumetric MRI (vMRI) were assessed. A total of 1,512 participants underwent one or more biomarker assessments; 154 developed incident ARIA-E. No differences were observed at baseline between ARIA-E and non-ARIA-E participants in brain amyloid burden by PET, the majority of vMRI measures, or CSF biomarkers, with the exception of lower baseline CSF Aβ 42 in APOE ε4 noncarrier ARIA-E vs non-ARIA-E groups (bapineuzumab non-ARIA-E p = 0.027; placebo non-ARIA-E p = 0.012). At week 71, bapineuzumab-treated participants with ARIA-E vs non-ARIA-E showed greater reduction in brain amyloid PET, greater reductions in CSF phosphorylated tau (p-tau) (all comparisons p < 0.01), and total tau (t-tau) (all comparisons p < 0.025), and greater hippocampal volume reduction and ventricular enlargement (all p < 0.05). Greater reduction in CSF Aβ 40 concentrations was observed for ARIA-E versus both non-ARIA-E groups (bapineuzumab/placebo non-ARIA-E p = 0.015/0.049). No group differences were observed at week 71 for changes in whole brain volume or CSF Aβ 42 . Baseline biomarkers largely do not predict risk for developing ARIA-E. ARIA-E was associated with significant longitudinal changes in several biomarkers, with larger reductions in amyloid PET and CSF p-tau and t-tau concentrations, and paradoxically greater hippocampal volume reduction and ventricular enlargement, suggesting that ARIA-E in bapineuzumab-treated cases may be related to increased Aβ efflux from the brain and affecting downstream pathogenic processes. © 2018 American Academy of Neurology.

  2. Paleoecología y gestión del combustible en la ocupación del Auriñaciense arcaico de la cueva de El Castillo (Puente Viesgo, Cantabria

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    Victoria Cabrera Valdés

    1999-01-01

    Full Text Available El análisis antracológico correspondiente al nivel 18 (Auriñaciense arcaico de la cueva del Castillo (Cantabria, Norte de España, ha puesto en evidencia una flora compuesta por Betu\\a, P'mus t. sylvestris y Sorbus aria. Las dataciones "C en espectrometría de masa por acelerador obtenidas sobre carbón, sitúan este nivel en el Pleniglaciar medio (37-40Ka.. Las estimaciones paleoambientales obtenidas a través de los estudios de los glaciares de las montañas cantábricas y del Pirineo occidental, nos han permitido correlacionar la Antracología y el Glaciarismo. El paisaje vegetal alrededor del habitat prehistórico estaría compuesto esencialmente por especies pioneras que tian coionizado unos sueios Ubres de hieios pero sometidos a condiciones periglaciares debido a que este iiabitat estaba próximo de ia cota aititudinal aicanzada por ios giaciares de montaña. Estos serian responsabies en parte dei desfase aititudinai y zonai de ia vegetación si io comparamos con ias condiciones actuaies. Los trayectos diarios recorridos por ios grupos liumanos a ia búsqueda de recursos económicos diversos, entre ellos la leña para encender fuego, se verían infiuídos en gran parte por estos condicionantes ambientaies.Charcoal analysis from archaeological levéis oí El Castillo (Cantabria, Northern Spain, have yielded Betula; Pinus t. sylvestris and Sorbus aria. The AMS C obtained on the same samples place these levéis on the Middie Pleniglacial (37-40Ka.. Palaeoenvironmental results obtained in glacial deposits from Cantabrian mountains and western Pyrenees let us to compare charcoal analysis and glaciation patterns. Landscape around this prehistoric settiement is formed essentially by pioneer vegetation cover along free-glace areas but under periglacial conditions. Altitudinal position of this site and ttie glaciai zones are similar. This particuiarity explain the altitudinal gap of the vegetation in tiiis área. Diary routes tallen by humans

  3. Ground beetle (Coleoptera: Carabidae) assemblages in narrow hedgerows in a Danish agricultural landscape

    DEFF Research Database (Denmark)

    Lövei, G. L.; Magura, T.

    2015-01-01

    Sorbus intermedia), and the non-native spruce (Picea spp.). We hypothesised that hedgerows with deciduous trees harbour more diverse ground beetle assemblages than hedges composed of non-native conifer trees. We also investigated which vegetation structure characteristics might influence the ground...

  4. Punaste õhtute purpur / Jüri Annist

    Index Scriptorium Estoniae

    Annist, Jüri, 1950-

    2015-01-01

    Punane tamm, punane vaher, jaapani juudapuulehik, äädikapuu, pihlaka Sorbus sort 'Dodong' ja tiivulise kikkapuu sort 'Compactus' värvuvad sügisel kaunilt punaseks. Autori arvates on kõige punasem sügisvärvus tiivulisel kikkapuul 'Compactus'

  5. Assessing the extent and effects of herbicide drift into Danish hedgerows

    DEFF Research Database (Denmark)

    Bruus, M.; Strandberg, M. T.; Andersen, H. V.

    Very low dosages of herbicides are known to cause effects on bird cherry (Prunus avium) and hawthorn (Crataegus monogyna). With the purpose of studying whether this is a general phenomenon two other common hedgerow species, Sambucus nigra (elder) and Sorbus intermedia (Swedish whitebeam), were...

  6. The diversity of microhabitats and their impact on the regeneration of spruce and rowan in the mountain forests of the Low Tatras

    International Nuclear Information System (INIS)

    Gloncak, P.

    2010-01-01

    In this paper the authors describe the questions: what is proportion of different types of microhabitats in natural spruce?; which types of microhabitats prefers spruce (Picea abies) and rowan (Sorbus aucuparia) in the early stages of their development?; what role do ground vegetation and dead wood play?

  7. The diversity of microhabitats and their impact on the regeneration of spruce and rowan in the mountain forests of the Low Tatras

    International Nuclear Information System (INIS)

    Gloncak, P.

    2010-01-01

    In this presentation the authors describe the questions: what is proportion of different types of microhabitats in natural spruce?; which types of microhabitats prefers spruce (Picea abies) and rowan (Sorbus aucuparia) in the early stages of their development?; what role do ground vegetation and dead wood play?

  8. 7 CFR 301.51-2 - Regulated articles.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Regulated articles. 301.51-2 Section 301.51-2... Regulated articles. The following are regulated articles: (a) Firewood (all hardwood species), and green... (sycamore), Populus (poplar), Salix (willow), Sorbus (mountain ash), and Ulmus (elm). (b) Any other article...

  9. Surface tension phenomena in the xylem sap of three diffuse porous temperate tree species

    Science.gov (United States)

    K. K. Christensen-Dalsgaard; M. T. Tyree; P. G. Mussone

    2011-01-01

    In plant physiology models involving bubble nucleation, expansion or elimination, it is typically assumed that the surface tension of xylem sap is equal to that of pure water, though this has never been tested. In this study we collected xylem sap from branches of the tree species Populus tremuloides, Betula papyrifera and Sorbus...

  10. [ARIA Mexico 2014. Adaptation of the Clinical Practice Guide ARIA 2010 for Mexico. Methodology ADAPTE].

    Science.gov (United States)

    Larenas-Linnemann, Désirée; Mayorga-Butrón, José Luis; Sánchez-González, Andrés; Ramírez-García, Arturo; Medina-Ávalos, Miguel; Figueroa-Morales, Marco Antonio; Montaño-Velázquez, B Beatriz; Montes-Narváez, Gabriel; Romero-Tapia, Sergio; Stone-Aguilar, Héctor; Xochihua-Díaz, Luis; Salas-Hernández, Jorge; Hernán-Ruiz, Héctor; Betancourt-Suárez, Miguel A; Cano-Salas, María Carmen; Curiel-Aceves, Lorenzo; Dibildox-Martínez, Javier; Fernández-Vega, Margarita; García-Bolaños, Carlos; Iduñate-Palacios, Fernando; Jiménez-Chobillon, M Alejandro; López-Lizárraga, Doris N; Matta-Campos, Juan José; Olvera-Salinas, Jorge; Rivera-Gómez, María Antonia; Virgen-Ortega, César; Sienra-Monge, Juan José; Del Río-Navarro, Blanca; Arias-Cruz, Alfredo; Sacre-Hazouri, Antonio; Aguilar-Aranda, Ambrocio; Vásquez Del Mercado-Cordero, Rodrigo; Barnica, Raúl Humberto; Velasco-Hidalgo, Liliana; Solís-Galicia, Cecilia

    2014-01-01

    The global prevalence of allergic rhinitis is high. International Study of Asthma and Allergies in Childhood (ISAAC) Phase III reports a total estimated prevalence of 4.6% in Mexico. There is evidence based on allergic rhinitis Clinical Practice Guidelines (CPG), but its promotion, acceptance and application is not optimal or adequate in Mexico. To generate a guideline for the treatment of allergic rhinitis and its impact on asthma by adaptating the 2010 ARIA Guideline to Mexican reality, through a transculturation process applying the ADAPTE methodology. Using the ADAPTE Methodology, the original 2010 ARIA CPG recommendations were evaluated by the guideline development group (GDG) into which multiple medical specialities managing patients with allergic rhinitis were incoorporated. The GDG valorated the quality of 2010 ARIA, checked and translated key clinical questions. Moreover, the GDG adjusted recommendations, patient preferences and included comments in the context of the Mexican reality (safety, costs and cultural issues). To accomplish this, we ran Delphi panels with as many rounds as necessary to reach agreement. One extra question, not included in the original 2010 ARIA, on the use of Nasal Lavages for AR was created sustained by a systematic literature review. A total of 45 questions from the original 2010 ARIA were included and divided into six groups covering prevention, medical treatment, immunotherapy and alternative medicine to treat patients with allergic rhinitis with or without asthma. Most of the questions reached agreement in one or two rounds; one question required three rounds. An easy-to-use, adaptated, up-to-date and applicable allergic rhinitis guideline for Mexico is now available.

  11. ARIA Mexico 2014 Adaptation of the Clinical Practice Guide ARIA 2010 for Mexico. Methodology ADAPTE

    Directory of Open Access Journals (Sweden)

    Désirée Larenas-Linnemann

    2014-11-01

    Full Text Available Background: The global prevalence of allergic rhinitis is high. International Study of Asthma and Allergies in Childhood (ISAAC Phase III reports a total estimated prevalence of 4.6% in Mexico. There is evidence based on allergic rhinitis Clinical Practice Guidelines (CPG, but its promotion, acceptance and application is not optimal or adequate in Mexico. Objective: To generate a guideline for the treatment of allergic rhinitis and its impact on asthma by adaptating the 2010 ARIA Guideline to Mexican reality, through a transculturation process applying the ADAPTE methodology. Material and method: Using the ADAPTE Methodology, the original 2010 ARIA CPG recommendations were evaluated by the guideline development group (GDG into which multiple medical specialities managing patients with allergic rhinitis were incoorporated. The GDG valorated the quality of 2010 ARIA, checked and translated key clinical questions. Moreover, the GDG adjusted recommendations, patient preferences and included comments in the context of the Mexican reality (safety, costs and cultural issues. To accomplish this, we ran Delphi panels with as many rounds as necessary to reach agreement. One extra question, not included in the original 2010 ARIA, on the use of Nasal Lavages for AR was created sustained by a systematic literature review. Results: A total of 45 questions from the original 2010 ARIA were included and divided into six groups covering prevention, medical treatment, immunotherapy and alternative medicine to treat patients with allergic rhinitis with or without asthma. Most of the questions reached agreement in one or two rounds; one question required three rounds. Conclusions: An easy-to-use, adaptated, up-to-date and applicable allergic rhinitis guideline for Mexico is now available.

  12. Assessment of liquefaction potential during earthquakes by arias intensity

    Science.gov (United States)

    Kayen, R.E.; Mitchell, J.K.

    1997-01-01

    An Arias intensity approach to assess the liquefaction potential of soil deposits during earthquakes is proposed, using an energy-based measure of the severity of earthquake-shaking recorded on seismograms of the two horizontal components of ground motion. Values representing the severity of strong motion at depth in the soil column are associated with the liquefaction resistance of that layer, as measured by in situ penetration testing (SPT, CPT). This association results in a magnitude-independent boundary that envelopes initial liquefaction of soil in Arias intensity-normalized penetration resistance space. The Arias intensity approach is simple to apply and has proven to be highly reliable in assessing liquefaction potential. The advantages of using Arias intensity as a measure of earthquake-shaking severity in liquefaction assessment are: Arias intensity is derived from integration of the entire seismogram wave form, incorporating both the amplitude and duration elements of ground motion; all frequencies of recorded motion are considered; and Arias intensity is an appropriate measure to use when evaluating field penetration test methodologies that are inherently energy-based. Predictor equations describing the attenuation of Arias intensity as a function of earthquake magnitude and source distance are presented for rock, deep-stiff alluvium, and soft soil sites.

  13. ARIA 2016

    DEFF Research Database (Denmark)

    Bousquet, J.; Hellings, P W; Agache, I

    2016-01-01

    The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop gui...

  14. Impact of large herbivores on mountain forest stands in the Beskydy Mountains

    Czech Academy of Sciences Publication Activity Database

    Homolka, Miloslav; Heroldová, Marta

    2003-01-01

    Roč. 181, 1-2 (2003), s. 119-129 ISSN 0378-1127. [International conference on Forest Dynamics and Ungulate Herbivory. Davos, 03.10.2001-06.10.2001] R&D Projects: GA MŽP ZZ/620/2/97; GA AV ČR IBS6093003 Institutional research plan: CEZ:AV0Z6093917 Keywords : roe deer * red deer * Sorbus aucuparia Subject RIV: EG - Zoology Impact factor: 1.207, year: 2003

  15. SIERRA Multimechanics Module: Aria User Manual Version 4.42.

    Energy Technology Data Exchange (ETDEWEB)

    Sierra Thermal/Fluid Team

    2016-10-01

    Aria is a Galerkin finite element based program for solving coupled-physics problems described by systems of PDEs and is capable of solving nonlinear, implicit, transient and direct-to-steady state problems in two and three dimensions on parallel architectures. The suite of physics currently supported by Aria includes thermal energy transport, species transport, and electrostatics as well as generalized scalar, vector and tensor transport equations. Additionally, Aria includes support for manufacturing process flows via the incompressible Navier-Stokes equations specialized to a low Reynolds number (Re %3C 1) regime. Enhanced modeling support of manufacturing processing is made possible through use of either arbitrary Lagrangian- Eulerian (ALE) and level set based free and moving boundary tracking in conjunction with quasi-static nonlinear elastic solid mechanics for mesh control. Coupled physics problems are solved in several ways including fully-coupled Newton's method with analytic or numerical sensitivities, fully-coupled Newton- Krylov methods and a loosely-coupled nonlinear iteration about subsets of the system that are solved using combinations of the aforementioned methods. Error estimation, uniform and dynamic h-adaptivity and dynamic load balancing are some of Aria's more advanced capabilities. Aria is based upon the Sierra Framework.

  16. SIERRA Multimechanics Module: Aria User Manual Version 4.46.

    Energy Technology Data Exchange (ETDEWEB)

    Sierra Thermal/Fluid Team

    2017-09-01

    Aria is a Galerkin fnite element based program for solving coupled-physics problems described by systems of PDEs and is capable of solving nonlinear, implicit, transient and direct-to-steady state problems in two and three dimensions on parallel architectures. The suite of physics currently supported by Aria includes thermal energy transport, species transport, and electrostatics as well as generalized scalar, vector and tensor transport equations. Additionally, Aria includes support for manufacturing process fows via the incompressible Navier-Stokes equations specialized to a low Reynolds number ( %3C 1 ) regime. Enhanced modeling support of manufacturing processing is made possible through use of either arbitrary Lagrangian- Eulerian (ALE) and level set based free and moving boundary tracking in conjunction with quasi-static nonlinear elastic solid mechanics for mesh control. Coupled physics problems are solved in several ways including fully-coupled Newton's method with analytic or numerical sensitivities, fully-coupled Newton- Krylov methods and a loosely-coupled nonlinear iteration about subsets of the system that are solved using combinations of the aforementioned methods. Error estimation, uniform and dynamic h -adaptivity and dynamic load balancing are some of Aria's more advanced capabilities. Aria is based upon the Sierra Framework.

  17. SIERRA Multimechanics Module: Aria User Manual Version 4.44

    Energy Technology Data Exchange (ETDEWEB)

    Sierra Thermal/Fluid Team

    2017-04-01

    Aria is a Galerkin fnite element based program for solving coupled-physics problems described by systems of PDEs and is capable of solving nonlinear, implicit, transient and direct-to-steady state problems in two and three dimensions on parallel architectures. The suite of physics currently supported by Aria includes thermal energy transport, species transport, and electrostatics as well as generalized scalar, vector and tensor transport equations. Additionally, Aria includes support for manufacturing process fows via the incompressible Navier-Stokes equations specialized to a low Reynolds number ( %3C 1 ) regime. Enhanced modeling support of manufacturing processing is made possible through use of either arbitrary Lagrangian- Eulerian (ALE) and level set based free and moving boundary tracking in conjunction with quasi-static nonlinear elastic solid mechanics for mesh control. Coupled physics problems are solved in several ways including fully-coupled Newton's method with analytic or numerical sensitivities, fully-coupled Newton- Krylov methods and a loosely-coupled nonlinear iteration about subsets of the system that are solved using combinations of the aforementioned methods. Error estimation, uniform and dynamic h -adaptivity and dynamic load balancing are some of Aria's more advanced capabilities. Aria is based upon the Sierra Framework.

  18. Antiproliferative effects of small fruit juices on several cancer cell lines.

    Science.gov (United States)

    Yoshizawa, Y; Kawaii, S; Urashima, M; Fukase, T; Sato, T; Tanaka, R; Murofushi, N; Nishimura, H

    2000-01-01

    Juices prepared from small fruits, mainly growing in the northern part of Japan, were studied in an attempt to explore the feasibility of an assay that screens cytotoxic properties. Screening of 43 small fruit juices indicated that Actinidia polygama Maxim., Rosa rugosa Thunb., Vaccinium smallii A. Gray and Sorbus sambucifolia Roem, strongly inhibited the proliferation of all cancer cell lines examined and yet these juices were substantially less cytotoxic toward normal human cell lines.

  19. Um metaromance histórico: «Jaguar en Llamas», Arturo Arias

    Directory of Open Access Journals (Sweden)

    Márcia Paraquett

    2011-10-01

    Full Text Available Resumo: O romance histórico Jaguar en llamas, do escritor guatemalteco Arturo Arias, parodia a história de seu país, subvertendo a história oficial, conforme o procedimento utilizado por outros autores hispano-americanos no final do século XX. Esse romance, no entanto, não se constrói segundo o paradigma convencional, o que o torna um meta romance histórico.Palavras-chave: Literatura guatemalteca; Arturo Arias; Jaguar en Llamas; paródia; romance histórico.Resumen: La novela histórica Jaguar en llamas, del escritor gualtemalteco Arturo Arias, parodia la historia de su país, subvertiendo la historia oficial, de acuerdo con el procedimiento de otros autores hispanoamericanos en el fin del siglo XX, aunque no se construya según el paradigma convencional, lo que hace con que esa novela sea leída y vista como una meta novela histórica.Palabras-clave: Literatura guatemalteca; Arturo Arias; Jaguar en Llamas; parodia; novela histórica.Keywords: Guatemalan literature; Arturo Arias; Jaguar en Llamas; parody; historical novel.

  20. SIERRA Multimechanics Module: Aria User Manual – Version 4.40

    Energy Technology Data Exchange (ETDEWEB)

    Notz, Patrick K. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Subia, Samuel Ramirez [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hopkins, Matthew M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Moffat, Harry K. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Noble, David R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Okusanya, Tolulope O. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-05-02

    Aria is a Galerkin finite element based program for solving coupled-physics problems described by systems of PDEs and is capable of solving nonlinear, implicit, transient and direct-to-steady state problems in two and three dimensions on parallel architectures. The suite of physics currently supported by Aria includes thermal energy transport, species transport, and electrostatics as well as generalized scalar, vector and tensor transport equations. Additionally, Aria includes support for manufacturing process flows via the incompressible Navier-Stokes equations specialized to a low Reynolds number (Re < 1) regime. Enhanced modeling support of manufacturing processing is made possible through use of either arbitrary Lagrangian- Eulerian (ALE) and level set based free and moving boundary tracking in conjunction with quasi-static nonlinear elastic solid mechanics for mesh control. Coupled physics problems are solved in several ways including fully-coupled Newton’s method with analytic or numerical sensitivities, fully-coupled Newton- Krylov methods and a loosely-coupled nonlinear iteration about subsets of the system that are solved using combinations of the aforementioned methods. Error estimation, uniform and dynamic ℎ-adaptivity and dynamic load balancing are some of Aria’s more advanced capabilities. Aria is based upon the Sierra Framework.

  1. Assessing the extent and effects of herbicide drift into Danish hedgerows

    DEFF Research Database (Denmark)

    Pedersen, Marianne Bruus; Andersen, H. V.; Strandberg, M. T.

    Very low dosages of herbicides are known to cause effects on bird cherry (Prunus avium) and hawthorn (Crataegus monogyna). It is not yet known whether other hedgerow trees and shrubs are equally sensitive to herbicide drift, to which extent spray drift into hedges and other habitats close to fiel...... were assessed. Metsulfuron methyl effects on Sambucus nigra (elder) and Sorbus intermedia were studied in separate experiments and will include second year effects. Methods and preliminary results are presented and discussed in relation to pesticide regulation....

  2. ARIA: Delivering state-of-the-art InSAR products to end users

    Science.gov (United States)

    Agram, P. S.; Owen, S. E.; Hua, H.; Manipon, G.; Sacco, G. F.; Bue, B. D.; Fielding, E. J.; Yun, S. H.; Simons, M.; Webb, F.; Rosen, P. A.; Lundgren, P.; Liu, Z.

    2016-12-01

    Advanced Rapid Imaging and Analysis (ARIA) Center for Natural Hazards aims to bring state-of-the-art geodetic imaging capabilities to an operational level in support of local, national, and international hazard response communities. ARIA project's first foray into operational generation of InSAR products was with Calimap Project, in collaboration with ASI-CIDOT, using X-band data from the Cosmo-SkyMed constellation. Over the last year, ARIA's processing infrastructure has been significantly upgraded to exploit the free stream of high quality C-band SAR data from ESA's Sentinel-1 mission and related algorithmic improvements to the ISCE software. ARIA's data system can now operationally generate geocoded unwrapped phase and coherence products in GIS-friendly formats from Sentinel-1 TOPS mode data in an automated fashion, and this capability is currently being exercised various study sites across the United States including Hawaii, Central California, Iceland and South America. The ARIA team, building on the experience gained from handling X-band data and C-band data, has also built an automated machine learning-based classifier to label the auto-generated interferograms based on phase unwrapping quality. These high quality "time-series ready" InSAR products generated using state-of-the-art processing algorithms can be accessed by end users using two different mechanisms - 1) a Faceted-search interface that includes browse imagery for quick visualization and 2) an ElasticSearch-based API to enable bulk automated download, post-processing and time-series analysis. In this talk, we will present InSAR results from various global events that ARIA system has responded to. We will also discuss the set of geospatial big data tools including GIS libraries and API tools, that end users will need to familiarize themselves with in order to maximize the utilization of continuous stream of InSAR products from the Sentinel-1 and NISAR missions that the ARIA project will generate.

  3. Improved reliability, accuracy and quality in automated NMR structure calculation with ARIA

    Energy Technology Data Exchange (ETDEWEB)

    Mareuil, Fabien [Institut Pasteur, Cellule d' Informatique pour la Biologie (France); Malliavin, Thérèse E.; Nilges, Michael; Bardiaux, Benjamin, E-mail: bardiaux@pasteur.fr [Institut Pasteur, Unité de Bioinformatique Structurale, CNRS UMR 3528 (France)

    2015-08-15

    In biological NMR, assignment of NOE cross-peaks and calculation of atomic conformations are critical steps in the determination of reliable high-resolution structures. ARIA is an automated approach that performs NOE assignment and structure calculation in a concomitant manner in an iterative procedure. The log-harmonic shape for distance restraint potential and the Bayesian weighting of distance restraints, recently introduced in ARIA, were shown to significantly improve the quality and the accuracy of determined structures. In this paper, we propose two modifications of the ARIA protocol: (1) the softening of the force field together with adapted hydrogen radii, which is meaningful in the context of the log-harmonic potential with Bayesian weighting, (2) a procedure that automatically adjusts the violation tolerance used in the selection of active restraints, based on the fitting of the structure to the input data sets. The new ARIA protocols were fine-tuned on a set of eight protein targets from the CASD–NMR initiative. As a result, the convergence problems previously observed for some targets was resolved and the obtained structures exhibited better quality. In addition, the new ARIA protocols were applied for the structure calculation of ten new CASD–NMR targets in a blind fashion, i.e. without knowing the actual solution. Even though optimisation of parameters and pre-filtering of unrefined NOE peak lists were necessary for half of the targets, ARIA consistently and reliably determined very precise and highly accurate structures for all cases. In the context of integrative structural biology, an increasing number of experimental methods are used that produce distance data for the determination of 3D structures of macromolecules, stressing the importance of methods that successfully make use of ambiguous and noisy distance data.

  4. Pharmacologic and anti-IgE treatment of allergic rhinitis ARIA update (in collaboration with GA2LEN)

    NARCIS (Netherlands)

    Bousquet, J.; van Cauwenberge, P.; Aït Khaled, N.; Bachert, C.; Baena-Cagnani, C. E.; Bouchard, J.; Bunnag, C.; Canonica, G. W.; Carlsen, K.-H.; Chen, Y.-Z.; Cruz, A. A.; Custovic, A.; Demoly, P.; Dubakiene, R.; Durham, S.; Fokkens, W.; Howarth, P.; Kemp, J.; Kowalski, M. L.; Kvedariene, V.; Lipworth, B.; Lockey, R.; Lund, V.; Mavale-Manuel, S.; Meltzer, E. O.; Mullol, J.; Naclerio, R.; Nekam, K.; Ohta, K.; Papadopoulos, N.; Passalacqua, G.; Pawankar, R.; Popov, T.; Potter, P.; Price, D.; Scadding, G.; Simons, F. E. R.; Spicak, V.; Valovirta, E.; Wang, D.-Y.; Yawn, B.; Yusuf, O.

    2006-01-01

    The pharmacologic treatment of allergic rhinitis proposed by ARIA is an evidence-based and step-wise approach based on the classification of the symptoms. The ARIA workshop, held in December 1999, published a report in 2001 and new information has subsequently been published. The initial ARIA

  5. Dicty_cDB: Contig-U12232-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 15 EF494754_1( EF494754 |pid:none) Sorbus aucuparia isolate SaucS7b s... 87 1e-15 EU247098_1( EU247098 |pid:none) Pyrus syria...or S... 79 5e-13 EU247101_1( EU247101 |pid:none) Pyrus syriaca S5 RNase gene, par...247097 |pid:none) Pyrus syriaca S1 RNase gene, parti... 94 1e-17 CR382132_1073( CR382132 |pid:none) Yarrowia...EU294324 |pid:none) Prunus webbii S10-RNase gene, part... 94 1e-17 EU247097_1( EU

  6. Graphical analysis of NMR structural quality and interactive contact map of NOE assignments in ARIA

    Directory of Open Access Journals (Sweden)

    Malliavin Thérèse E

    2008-06-01

    Full Text Available Abstract Background The Ambiguous Restraints for Iterative Assignment (ARIA approach is widely used for NMR structure determination. It is based on simultaneously calculating structures and assigning NOE through an iterative protocol. The final solution consists of a set of conformers and a list of most probable assignments for the input NOE peak list. Results ARIA was extended with a series of graphical tools to facilitate a detailed analysis of the intermediate and final results of the ARIA protocol. These additional features provide (i an interactive contact map, serving as a tool for the analysis of assignments, and (ii graphical representations of structure quality scores and restraint statistics. The interactive contact map between residues can be clicked to obtain information about the restraints and their contributions. Profiles of quality scores are plotted along the protein sequence, and contact maps provide information of the agreement with the data on a residue pair level. Conclusion The graphical tools and outputs described here significantly extend the validation and analysis possibilities of NOE assignments given by ARIA as well as the analysis of the quality of the final structure ensemble. These tools are included in the latest version of ARIA, which is available at http://aria.pasteur.fr. The Web site also contains an installation guide, a user manual and example calculations.

  7. Aria `96; ARIA `96

    Energy Technology Data Exchange (ETDEWEB)

    Risica, S; Di Ciaccio, P [eds.; Istituto Superiore di Sanita` , Rome (Italy). Lab. di Fisica

    1996-03-01

    The Congress is devoted to the study of the indoor air quality in different types of indoor environments: work and life environments, transportation and leisure environments. In the various sessions, the different aspects of indoor pollution (health effects, detection and measurement of pollutants, legislation, experimental techniques, etc.) were presented and discussed. The high number of invited and submitted papers gives an idea of the numerous research activities performed in Italy in this field and proves the interest in this kind of interdisciplinary seminars, where physicists, chemists, physicians, engineers, architects and many other professional meet in a single scientific effort to improve the quality of life. [Italiano] Il Convegno e` dedicato allo studio della qualita` dell`aria nei diversi tipi di ambienti interni: gli ambienti di vitae di lavoro, i mezzi di trasporto, i luoghi del tempo libero. Le diverse sessioni affrontano, in modo interdisciplinare, i vari aspetti dell`inquinamento cioe` gli effetti suulla salute, la determinazione e la misura degli inquinanti, la normativa, le attivita` internazionali nel settore, ecc. L`elevato numero di relazioni ad invito e comunicazioni raccolte testimonia non solo i numerosi progetti di ricercasviluppati in Italia su queste tematiche, ma anche l`interesse per questo tipo di incontri che vedono confrontarsi fisici, chimici, ingegneri, architetti e numerose altre figure professionali in un unico sforzo scientifico per il miglioramento della qualita` della vita.

  8. [Aria con violines al Santísimo Sacramento. Ay, Dueño enamorado

    OpenAIRE

    Anónimo

    2010-01-01

    Tabla de contenido: 1. Violín primero; 2. Violín segundo; 3. Violón; 4. Órgano; 5. Recitado y aria.Folio 1. Violín primero.Folio 3. Violín segundo.Folio 5. Violón.Folio 7. Órgano.Folio 9. Recitado y aria.Folio 9-10. Letra.

  9. Effects of Drought and Rewetting on Growth and Gas Exchange of Minor European Broadleaved Tree Species

    Directory of Open Access Journals (Sweden)

    Jörg Kunz

    2016-10-01

    Full Text Available Widespread and economically important European tree species such as Norway spruce, Scots pine, and European beech are projected to be negatively affected by the increasing intensity and frequency of dry and hot conditions in a future climate. Hence, there is an increasing need to investigate the suitability of presumably more drought tolerant species to ensure future ecological stability, biodiversity, and productivity of forests. Based on their distribution patterns and climatic envelopes, the rare, minor broadleaved tree species Sorbus torminalis ((L. CRANTZ, S. domestica (L., Acer campestre (L., and A. platanoides (L. are assumed to be drought tolerant, however, there is only limited experimental basis to support that notion. This study aimed at quantifying growth and gas exchange of seedlings of these species during drought conditions, and their capacity to recover following drought. For that purpose, they were compared to the common companion species Quercus petraea ((MATTUSCHKA LIEBL. and Fagus sylvatica (L.. Here, potted seedlings of these species were exposed to water limitation followed by rewetting cycles in a greenhouse experiment. Photosynthesis and transpiration rates, stomatal conductance as well as root and shoot growth rates indicated a high drought resistance of A. campestre and A. platanoides. Sorbus domestica showed a marked ability to recover after drought stress. Therefore, we conclude that these minor tree species have the potential to enrich forests on drought-prone sites. Results from this pot experiment need to be complemented by field studies, in which the drought response of the species is not influenced by restrictions to root development.

  10. SU-D-BRD-07: Automatic Patient Data Audit and Plan Quality Check to Support ARIA and Eclipse

    Energy Technology Data Exchange (ETDEWEB)

    Li, X; Li, H; Wu, Y; Mutic, S; Yang, D [Washington University School of Medicine, St. Louis, MO (United States)

    2014-06-01

    Purpose: To ensure patient safety and treatment quality in RT departments that use Varian ARIA and Eclipse, we developed a computer software system and interface functions that allow previously developed electron chart checking (EcCk) methodologies to support these Varian systems. Methods: ARIA and Eclipse store most patient information in its MSSQL database. We studied the contents in the hundreds database tables and identified the data elements used for patient treatment management and treatment planning. Interface functions were developed in both c-sharp and MATLAB to support data access from ARIA and Eclipse servers using SQL queries. These functions and additional data processing functions allowed the existing rules and logics from EcCk to support ARIA and Eclipse. Dose and structure information are important for plan quality check, however they are not stored in the MSSQL database but as files in Varian private formats, and cannot be processed by external programs. We have therefore implemented a service program, which uses the DB Daemon and File Daemon services on ARIA server to automatically and seamlessly retrieve dose and structure data as DICOM files. This service was designed to 1) consistently monitor the data access requests from EcCk programs, 2) translate the requests for ARIA daemon services to obtain dose and structure DICOM files, and 3) monitor the process and return the obtained DICOM files back to EcCk programs for plan quality check purposes. Results: EcCk, which was previously designed to only support MOSAIQ TMS and Pinnacle TPS, can now support Varian ARIA and Eclipse. The new EcCk software has been tested and worked well in physics new start plan check, IMRT plan integrity and plan quality checks. Conclusion: Methods and computer programs have been implemented to allow EcCk to support Varian ARIA and Eclipse systems. This project was supported by a research grant from Varian Medical System.

  11. SU-D-BRD-07: Automatic Patient Data Audit and Plan Quality Check to Support ARIA and Eclipse

    International Nuclear Information System (INIS)

    Li, X; Li, H; Wu, Y; Mutic, S; Yang, D

    2014-01-01

    Purpose: To ensure patient safety and treatment quality in RT departments that use Varian ARIA and Eclipse, we developed a computer software system and interface functions that allow previously developed electron chart checking (EcCk) methodologies to support these Varian systems. Methods: ARIA and Eclipse store most patient information in its MSSQL database. We studied the contents in the hundreds database tables and identified the data elements used for patient treatment management and treatment planning. Interface functions were developed in both c-sharp and MATLAB to support data access from ARIA and Eclipse servers using SQL queries. These functions and additional data processing functions allowed the existing rules and logics from EcCk to support ARIA and Eclipse. Dose and structure information are important for plan quality check, however they are not stored in the MSSQL database but as files in Varian private formats, and cannot be processed by external programs. We have therefore implemented a service program, which uses the DB Daemon and File Daemon services on ARIA server to automatically and seamlessly retrieve dose and structure data as DICOM files. This service was designed to 1) consistently monitor the data access requests from EcCk programs, 2) translate the requests for ARIA daemon services to obtain dose and structure DICOM files, and 3) monitor the process and return the obtained DICOM files back to EcCk programs for plan quality check purposes. Results: EcCk, which was previously designed to only support MOSAIQ TMS and Pinnacle TPS, can now support Varian ARIA and Eclipse. The new EcCk software has been tested and worked well in physics new start plan check, IMRT plan integrity and plan quality checks. Conclusion: Methods and computer programs have been implemented to allow EcCk to support Varian ARIA and Eclipse systems. This project was supported by a research grant from Varian Medical System

  12. Photo of the alignment for the ARIA experiment

    CERN Multimedia

    Brice, Maximilien

    2017-01-01

    Photo of the alignment for the ARIA experiment. After placing the 3 modules next to each other on the floor in bdg 180, we will soon proceed to align them. That will imply lifting and rotations of some of the modules.

  13. Assessing future suitability of tree species under climate change by multiple methods: a case study in southern Germany

    Directory of Open Access Journals (Sweden)

    Helge Walentowski

    2017-07-01

    Full Text Available We compared results derived using three different approaches to assess the suitability of common tree species on the Franconian Plateau in southern Germany under projected warmer and drier climate conditions in the period 2061-2080. The study area is currently a relatively warm and dry region of Germany. We calculated species distribution models (SDMs using information on species’ climate envelopes to predict regional species spectra under 63 different climate change scenarios. We complemented this with fine-scale ecological niche analysis using data from 51 vegetation surveys in seven forest reserves in the study area, and tree-ring analysis (TRA from local populations of five tree species to quantify their sensitivity to climatic extreme years. The SDMs showed that predicted future climate change in the region remains within the climate envelope of certain species (e.g. Quercus petraea, whilst for e.g. Fagus sylvatica, future climate conditions in one third of the scenarios are too warm and dry. This was confirmed by the TRA: sensitivity to drought periods is lower for Q. petraea than for F. sylvatica. The niche analysis shows that the local ecological niches of Quercus robur and Fraxinus excelsior are mainly characterized by soils providing favorable water supply than by climate, and Pinus sylvestris (planted is strongly influenced by light availability. The best adapted species for a warmer and potentially drier climate in the study region are Acer campestre, Sorbus torminalis, S. aria, Ulmus minor, and Tilia platyphyllos, which should therefore play a more prominent role in future climate-resilient mixed forest ecosystems.

  14. CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis

    DEFF Research Database (Denmark)

    Bousquet, J; Onorato, G L; Bachert, C

    2017-01-01

    A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a Good Practice focusing on the implementation of multi-sectoral care pa...

  15. Antioxidant capacities of ten edible North American plants.

    Science.gov (United States)

    Acuña, Ulyana Muñoz; Atha, Daniel E; Ma, Jun; Nee, Michael H; Kennelly, Edward J

    2002-02-01

    The EtOAc extract obtained from ten edible North American plants, Acorus calamus, Clintonia borealis, Gaultheria shallon, Juniperus osteosperma, Opuntia polyacantha, Prunus americana, Prunus virginiana, Sambucus cerulea, Sorbus americana and Vaccinium parvifolium, were tested in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical assay. High antioxidant activity was obtained from the extracts of three fruits, Gaultheria shallon, Sambucus cerulea and Prunus americana and one extracted rhizome, Acorus calamus. Catechin and epicatechin, potent polyphenolic antioxidants, were identified in the EtOAc extracts of Gaultheria shallon and Sambucus cerulea by reversed-phase thin-layer chromatography (TLC) and reversed-phase high-performance liquid chromatography (HPLC). Copyright 2002 John Wiley & Sons, Ltd.

  16. Pengaruh Penerapan Pembelajaran Arias Dipadu Mind Map terhadap Hasil Belajar Kognitif Siswa Kelas VII

    OpenAIRE

    Leliavia, Leliavia; Al Muhdhar, Mimien Henie Irawati; Suwono, Hadi

    2017-01-01

    This research was to determine the effect of differences ARIAS combined mind map learning and ARIAS learning to cognitive learning outcomes grade VII SMPN 1 Tempunak. This research with quasy research experiment design approach with the design of pretest-posttest. Data were analyzed using descriptive statistics and inferensial to test the hypothesis that analysis of covariance (ANCOVA) using SPSS 23 for windows with a significance level of 0,05. The study was conducted at the grade VII SMPN 1...

  17. O universo da feitiçaria, magia e variantes

    Directory of Open Access Journals (Sweden)

    Hanciau, Nubia Jacques

    2009-01-01

    Full Text Available O texto a seguir apresenta a crítica de vocábulos e conceitos da história da feitiçaria, que reconhece não apenas “uma magia”, “uma bruxaria”, “uma feitiçaria”. Para a compreensão dos atos mágicos, algumas distinções básicas são necessárias, pois se sabe que existirão tantas práticas quantos forem os sistemas culturais e de acordo com as diversas singularidades do mental coletivo. Além disso, novos caminhos apresentam-se ao historiador contemporâneo, que privilegia os estudos dos simbolismos, das representações mentais, da magia, do mito e parentesco, o que o leva a ver com precaução os sistemas gerais de classificação ou as sínteses antropológicas, antes de qualquer retomada conceitual

  18. Astrophysics at RIA (ARIA) Working Group

    International Nuclear Information System (INIS)

    Smith, Michael S.; Schatz, Hendrik; Timmes, Frank X.; Wiescher, Michael; Greife, Uwe

    2006-01-01

    The Astrophysics at RIA (ARIA) Working Group has been established to develop and promote the nuclear astrophysics research anticipated at the Rare Isotope Accelerator (RIA). RIA is a proposed next-generation nuclear science facility in the U.S. that will enable significant progress in studies of core collapse supernovae, thermonuclear supernovae, X-ray bursts, novae, and other astrophysical sites. Many of the topics addressed by the Working Group are relevant for the RIKEN RI Beam Factory, the planned GSI-Fair facility, and other advanced radioactive beam facilities

  19. [ARIA (Allergic Rhinitis and its Impact on Asthma). Achievements in 10 years and future needs in Latin America].

    Science.gov (United States)

    Baena-Cagnani, Carlos E; Sánchez-Borges, Mario; Zernotti, Mario E; Larenas-Linnemann, Désireé; Cruz, Alvaro A; González-Díaz, Sandra N; Ivancevich, Juan C; Aldrey-Palacios, Oscar; Sisul, Juan C; Solé, Dirceu; Cepeda, Alfonso M; Jares, Edgardo J; Calvo Gil, Mario; Valentin-Rostán, Marylin; Yáñez, Anahí; Gereda, José; Cardona-Villa, Ricardo; Rosario, Nelson; Croce, Víctor H; Bachert, Claus; Canonica, G Walter; Demoly, Pascal; Passalacqua, Giovanni; Samolinski, Boleslaw; Schünemann, Holger J; Yorgancioglu, Arzu; Ansotegui, Ignacio J; Khaltaev, Nikolai; Bedbrook, Anna; Zuberbier, Torsten; Bousquet, Jean

    2013-01-01

    Allergic rhinitis and asthma represent global problems of public health affecting all age groups; asthma and allergic rhinitis frequently coexist in the same patients. In Latin American prevalence of allergic rhinitis, although variable, is very high. Allergic rhinitis and its Impact on Asthma (ARIA) started during a workshop of the World Health Organization performed in 1999 and was published in 2001. ARIA proposed a new classification of allergic rhinitis in intermittent or persistent and mild or moderate-severe. This approach of classification reflects more nearly the impact of allergic rhinitis in patients. In its review of 2010 ARIA developed guidelines for diagnosis and treatment of allergic rhinitis and of clinical practices for management of comorbidities of allergic rhinitis and asthma based on GRADE (Grading of Recommendations, Development and Evaluation). ARIA has been spread and implemented in more than 50 countries. In Latin American an intense activity has been developed to spread these recommendations in almost all the countries of the region and it is important to record the obtained goals in the diffusion and implementation of ARIA, as well as to identify the unsatisfied needs from the clinical, research and implementation points of view. Final objective is to reinforce the priority that allergy and asthma should have, especially in children, in the programs of public health, as they have been prioritized in European Union in 2011.

  20. Arias Montano, traductor: filosofía, técnicas y praxis multilingüe

    Directory of Open Access Journals (Sweden)

    Fernández Marcos, Natalio

    2012-06-01

    Full Text Available Arias Montano was one of the best orientalists of the 16th century. He is specially known as editor of the Antwerp Polyglot. He translated into Latin several originals of this Polyglot, and in his Biblical commentaries he provided a new translation for most of the passages. He was in favour of a literal translation and he even dared to correct Sanctes Pagnino’s Latin version. In his Biblical commentaries he utilized idioms of the European languages of his time, especially Castilian. In this article the authors comment these Castilian words, sentences and sayings used by Arias Montano to illustrate various passages. He did not include among his projects a Spanish translation of the Bible; but in the light of his linguistic sensitivity, the authors think that, if he would have done this version, he would possibly have been considered the best translator of the Bible into Spanish.

    Arias Montano fue uno de los mejores orientalistas del siglo XVI. Es conocido especialmente como editor de la Políglota de Amberes. Tradujo al latín diversos originales de esa Políglota y en sus comentarios bíblicos ofreció una nueva traducción de la mayoría de los pasajes. Partidario de la versión literal, llegó incluso a corregir la traducción latina de Sanctes Pagnino. En sus comentarios bíblicos recurrió a giros y modismos de las lenguas europeas de su tiempo, en especial el castellano. En este artículo los autores comentan palabras, dichos y refranes castellanos que sirvieron a Arias Montano para ilustrar algunos pasajes. No incluyó entre sus proyectos el traducir la Biblia al español, pero a la luz de la sensibilidad lingüística que demuestra, los autores piensan que, de haberlo llevado a cabo, tal vez Arias Montano hubiera sido considerado como el mejor traductor de la Biblia al castellano.

  1. John Cage's Aria viewed through the prism of contextual determination

    Directory of Open Access Journals (Sweden)

    Radovanović Bojana

    2017-01-01

    Full Text Available The paper analysis the three contextual layers of creating John Cage's Aria for solo voice performed by Cathy Berberia at the 'big stage' of musical neo-avant-garde in Darmstadt. The layers in question are: (1 the socio-political context of Germany after World War II, where the denazification process was started at the time, (2 the artistic context of neo-avant-garde musical milieu which was being formed in Darmstadt in that period, and (3 the context of a new epoch in the history of vocal art. The thesis presented here is that an encounter occurred between American experimental and European avant-garde musical practice during the accelerated denazification and liberalisation of German society and the establishment of the Cold War relationship between the East and the West. The piece Aria represents an example of a collaborative work between American and European artists, which turned to be an important step in the history of extended vocal techniques in musical performing and composing.

  2. CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report

    NARCIS (Netherlands)

    Bousquet, J.; Onorato, G. L.; Bachert, C.; Barbolini, M.; Bedbrook, A.; Bjermer, L.; de Sousa, J. Correia; Chavannes, N. H.; Cruz, A. A.; de Manuel Keenoy, E.; Devillier, P.; Fonseca, J.; Hun, S.; Kostka, T.; Hellings, P. W.; Illario, M.; Ivancevich, J. C.; Larenas-Linnemann, D.; Millot-Keurinck, J.; Ryan, D.; Samolinski, B.; Sheikh, A.; Yorgancioglu, A.; Agache, I.; Arnavielhe, S.; Bewick, M.; Annesi-Maesano, I.; Anto, J. M.; Bergmann, K. C.; Bindslev-Jensen, C.; Bosnic-Anticevich, S.; Bouchard, J.; Caimmi, D. P.; Camargos, P.; Canonica, G. W.; Cardona, V.; Carriazo, A. M.; Cingi, C.; Colgan, E.; Custovic, A.; Dahl, R.; Demoly, P.; de Vries, G.; Fokkens, W. J.; Fontaine, J. F.; Gemicioğlu, B.; Guldemond, N.; Gutter, Z.; Haahtela, T.; Hellqvist-Dahl, B.; Jares, E.; Joos, G.; Just, J.; Khaltaev, N.; Keil, T.; Klimek, L.; Kowalski, M. L.; Kull, I.; Kuna, P.; Kvedariene, V.; Laune, D.; Louis, R.; Magnan, A.; Malva, J.; Mathieu-Dupas, E.; Melén, E.; Menditto, E.; Morais-Almeida, M.; Mösges, R.; Mullol, J.; Murray, R.; Neffen, H.; O'Hehir, R.; Palkonen, S.; Papadopoulos, N. G.; Passalacqua, G.; Pépin, J. L.; Portejoie, F.; Price, D.; Pugin, B.; Raciborski, F.; Simons, F. E. R.; Sova, M.; Spranger, O.; Stellato, C.; Todo Bom, A.; Tomazic, P. V.; Triggiani, M.; Valero, A.; Valovirta, E.; Vandenplas, O.; Valiulis, A.; van Eerd, M.; Ventura, M. T.; Wickman, M.; Young, I.; Zuberbier, T.; Zurkuhlen, A.; Senn, A.

    2017-01-01

    A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a Good Practice focusing on the implementation of multi-sectoral care

  3. SU-D-BRD-01: An Automated Physics Weekly Chart Checking System Supporting ARIA

    Energy Technology Data Exchange (ETDEWEB)

    Chang, X; Yang, D [Washington University in St Louis, St Louis, MO (United States)

    2015-06-15

    Purpose: A software tool was developed in this study to perform automatic weekly physics chart check on the patient data in ARIA. The tool accesses the electronic patient data directly from ARIA server and checks the accuracy of treatment deliveries, and generates reports which summarize the delivery history and highlight the errors. Methods: The tool has four modules. 1) The database interface is designed to directly access treatment delivery data from the ARIA database before reorganizing the data into the patient chart tree (PCT). 2) PCT is a core data structure designed to store and organize the data in logical hierarchies, and to be passed among functions. 3) The treatment data check module analyzes the organized data in PCT and stores the checking results into PCT. 4) Report generation module generates reports containing the treatment delivery summary, chart checking results and plots of daily treatment setup parameters (couch table positions, shifts of image guidance). The errors that are found by the tool are highlighted with colors. Results: The weekly check tool has been implemented in MATLAB and clinically tested at two major cancer centers. Javascript, cascading style sheets (CSS) and dynamic HTML were employed to create the user-interactive reports. It takes 0.06 second to search the delivery records of one beam with PCT and compare the delivery records with beam plan. The reports, saved in the HTML files on shared network folder, can be accessed by web browser on computers and mobile devices. Conclusion: The presented weekly check tool is useful to check the electronic patient treatment data in Varian ARIA system. It could be more efficient and reliable than the manually check by physicists. The work was partially supported by a research grant from Varian Medical System.

  4. SU-D-BRD-01: An Automated Physics Weekly Chart Checking System Supporting ARIA

    International Nuclear Information System (INIS)

    Chang, X; Yang, D

    2015-01-01

    Purpose: A software tool was developed in this study to perform automatic weekly physics chart check on the patient data in ARIA. The tool accesses the electronic patient data directly from ARIA server and checks the accuracy of treatment deliveries, and generates reports which summarize the delivery history and highlight the errors. Methods: The tool has four modules. 1) The database interface is designed to directly access treatment delivery data from the ARIA database before reorganizing the data into the patient chart tree (PCT). 2) PCT is a core data structure designed to store and organize the data in logical hierarchies, and to be passed among functions. 3) The treatment data check module analyzes the organized data in PCT and stores the checking results into PCT. 4) Report generation module generates reports containing the treatment delivery summary, chart checking results and plots of daily treatment setup parameters (couch table positions, shifts of image guidance). The errors that are found by the tool are highlighted with colors. Results: The weekly check tool has been implemented in MATLAB and clinically tested at two major cancer centers. Javascript, cascading style sheets (CSS) and dynamic HTML were employed to create the user-interactive reports. It takes 0.06 second to search the delivery records of one beam with PCT and compare the delivery records with beam plan. The reports, saved in the HTML files on shared network folder, can be accessed by web browser on computers and mobile devices. Conclusion: The presented weekly check tool is useful to check the electronic patient treatment data in Varian ARIA system. It could be more efficient and reliable than the manually check by physicists. The work was partially supported by a research grant from Varian Medical System

  5. ARIA (allerjik rinit ve astım üzerine etkisi) 10 yıldaki kazanımlar ve gelecekteki gereksinimler

    NARCIS (Netherlands)

    Yorgancıoğlu, A.; Özdemir, C.; Kalaycı, Ö; Kalyoncu, A. F.; Bachert, C.; Baena-Cagnani, C. E.; Casale, T. B.; Chen, Y. Z.; Cruz, A. A.; Demoly, P.; Fokkens, W. J.; Lodrup Carlsen, K. C.; Mohammad, Y.; Mullol, J.; Ohta, K.; Papadopoulos, N. G.; Pawankar, R.; Samolinski, B.; Schünemann, H. J.; Yusuf, O. M.; Zuberbier, T.; Bousquet, J.

    2012-01-01

    Allergic rhinitis and asthma represent global health problems for all age groups. Asthma and rhinitis frequently co-exist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization (WHO) workshop in 1999 and was published in 2001. ARIA

  6. [Allergic Rhinitis and its Impact on Asthma (ARIA) in Latin America].

    Science.gov (United States)

    Baena-Cagnani, Carlos E

    2002-01-01

    Allergic rhinitis is the commonest chronic respiratory disorder in children and young adults having an important impact for those suffering this condition, as well as for the public health. Allergic rhinitis is frequently associated to other co-morbidities, particularly asthma and conjunctivitis but, also, sinusitis and otitis media. Most of patients suffering rhinitis are cared by GPs and pediatricians and there are evidences that allergic rhinitis is undertreated, particularly the moderate/severe persistent forms. Clinical guidelines have become an important tool providing recommendations for diagnosis and treatment of different medical conditions. They help the process of decision making for GPs and pediatricians, and many of them, contain an update on basic science and epidemiology. In respiratory medicine, guidelines on asthma and rhinitis are available; however, they do not look at the patients globally and focus the disorder on an organ-specific basis without recommendations on co-morbidities. ARIA, Allergic rhinitis and its impact on asthma, has not been developed only to update specialists in allergy/immunology, otorhinolaryngology and neumology on rhinitis and its comorbidities but, also, to provide recommendations for non-specialists. A new classification and severity of allergic rhinitis is proposed replacing the classic perennial and seasonal forms for persistent and intermittent, mild to moderate/severe. ARIA is an initiative in collaboration with the World Health Organization and the master document has been endorsed by many national and international scientific societies and organizations. ARIA is an evidence-based document also stressing on pediatric aspects and providing recommendations for low-income countries.

  7. Some Antifungal Properties of Sorbic Acid Extracted from Berries of Rowan (Sorbus Aucuparia).

    Science.gov (United States)

    Brunner, Ulrich

    1985-01-01

    The food preservative sorbic acid can be extracted from Eurasian mountain ash berries (commercially available) and used to show antifungal properties in microbiological investigations. Techniques for extraction, purification, ultraviolet analysis, and experiments displaying antifungal activity are described. A systematic search for similar…

  8. Chilocorus renipustulatus (Coleoptera: Coccinellidae) dominates predatory ladybird assemblages on Sorbus aucuparia (Rosales: Rosaceae)

    Czech Academy of Sciences Publication Activity Database

    Kula, E.; Nedvěd, Oldřich

    2011-01-01

    Roč. 108, č. 4 (2011), s. 603-608 ISSN 1210-5759 Grant - others:Ministry of Education of the Czech Republic(CZ) VZ MSM 6215648902; Ministry of Agriculture(CZ) QH82047 Institutional research plan: CEZ:AV0Z50070508 Keywords : Coccinellidae * Chilocorus renipustulatus * scale insect Subject RIV: EH - Ecology, Behaviour Impact factor: 1.061, year: 2011 http://www.eje.cz/scripts/viewabstract.php?abstract=1659

  9. Co-existence of Endometriotic Cyst of the Ovary and Arias-Stella Reaction in a Non-Pregnant Woman: Report of a Rare Case.

    Science.gov (United States)

    Harikrishnan, Volga; Esaki, Muthuvel; Srinivasan, Chitra; Arockiasamy, Parimala; Ethirajan, Shanthi

    2016-03-01

    Endometriosis is defined as presence of endometrial tissue outside the uterus. It can occur anywhere in the ovary. In the ovary it is usually presented as cyst, termed as endometriotic cyst or Chocolate cyst. Arias-Stella reaction is usually seen in gestational endometrium or in ectopic gestation site and rarely in non-pregnant uterus with hormonal intake. Co-existence of endometriosis and Arias-Stella reaction is very rare. We present a very rare case of endometriotic cyst of the ovary exhibiting Arias -Stella reaction which was seen in of non pregnant patient without any history of hormonal intake.

  10. Differentiation-inducing effects of small fruit juices on HL-60 leukemic cells.

    Science.gov (United States)

    Yoshizawa, Y; Kawaii, S; Urashima, M; Fukase, T; Sato, T; Murofushi, N; Nishimura, H

    2000-08-01

    Epidemiological studies indicate that high intakes of fruits and vegetables are associated with a reduced risk of cancer, and several plant-derived drugs have been developed in medical oncology. Since only a small part of the flora has been tested for any kind of bioactivity, we chose small fruits as sources of differentiation-inducing activity against HL-60 leukemic cells. We have prepared juices from various small fruits that grow mainly in the northern part of Japan. Screening of 43 samples indicated that juices of Actinidia polygama Maxim., Rosa rugosa Thunb., Vaccinium smallii A. Gray, and Sorbus sambucifolia Roem. strongly induced differentiation of HL-60 cells to monocyte/macrophage characteristics in a concentration-dependent manner as indicated by histochemical and biochemical examinations.

  11. Flowers visited by honey bee in southern Finland

    Directory of Open Access Journals (Sweden)

    Markku Käpylä

    1979-01-01

    Full Text Available A list of nectar and pollen sources of honeybee (Apis mellifera L. in southern Finland based on 44 500 flower records is presented. Only the common wild and cultivated species are included, 139 species altogether. The flowering times are shown with an accuracy of two weeks. The most important food sources during spring (April—May are Salix spp., and Tussilago farfara: during early summer (late May and June Salix spp., Taraxacum officinale, Acer platanoides, Vaccinium vitis-idaea, Barbarea vulgaris, Ribes spp., Malus domestica, Sorbus aucuparia, and Geranium sylvaticum; during mid-summer Trifolium repens, T. hybridum, Rubus idaeus, Tilia cordata, Epilobium angustifolium, and Cirsium arvense; during late summer and early autumn Calluna vulgaris, Arctium tomentosum, Sonchus arvensis and Leontodon autumnalis.

  12. Formas de controle do cotidiano da população urbana setecentista: o direito de almotaçaria

    OpenAIRE

    Pereira, Magnus Roberto de Mello

    2001-01-01

    A almotaçaria, uma das mais antigas e duradouras instituições das cidades de origem portuguesa foi praticamente ignorada pela historiografia. O presente artigo tem por objetivo resgatar esse tema. Procura demonstrar que as atribuições básicas do direito de almotaçaria (controle do mercado, do sanitário e do edificatório) revelam o núcleo profundo daquilo que era entendido como o urbano. A ciência política tem proposto que o Estado Moderno centralizado nasceu do aprofundamento e desdobramento ...

  13. Aria Sardinia: the on line community joining tradition and innovatiom

    Directory of Open Access Journals (Sweden)

    Fabrizio Lao

    2005-12-01

    Full Text Available The "ARIA Sardinia" project (Network Actions for Italians Abroad has been especially designed to integrate and give value to the network of relationships between public administrations, local socio-economic stakeholders and Italian communities abroad, this goal to be pursued with the support of new technologies and learning approaches emerging within the context of on line interest communities. The general objective of the project is the development of competencies and knowledge, intended to combine specific technical skills with local "territorial knowledge", in a process where the strengthening and the dissemination of these forms of culture come from the prompt use of innovative tools. The main activities of the project are the actions intended to guide and assist entrepreneurs, associations, development projects' partners or promoters in the path of acquisition and dissemination of the competencies which are necessary to the involvement of Italians abroad into the internationalization process of Sardinian economy. ARIA Sardinia was funded by the Italian Foreign Affairs Ministry and the European Social Fund (FSE, within the framework of the National Operational Program for Technical Assistance and System Action (PON ATAS aimed at specific promotion initiatives and fostering of permanent links between Southern Italy economy and Italians living abroad. Keywords: on line community, networking, Italians abroad, Sardinian economy, Sardinia, culture.

  14. Allergic rhinitis and its impact on asthma update (ARIA 2008)--western and Asian-Pacific perspective.

    Science.gov (United States)

    Pawankar, Ruby; Bunnag, Chaweewan; Chen, Yuzhi; Fukuda, Takeshi; Kim, You-Young; Le, Lan Thi Tuyet; Huong, Le Thi Thu; O'Hehir, Robyn E; Ohta, Ken; Vichyanond, Pakit; Wang, De-Yun; Zhong, Nanshan; Khaltaev, Nikolai; Bousquet, Jean

    2009-12-01

    The prevalence of allergic diseases such as allergic rhinitis (AR) and asthma is markedly increasing worldwide as societies adopt western life styles. Allergic sensitization is an important risk factor for asthma and AR, and asthma often co-exists with AR. An estimated 300 million people worldwide have asthma, about 50% of whom live in developing countries and about 400 million people suffer from AR. Yet, AR is often under-diagnosed and under-treated due to a lack of appreciation of the disease burden and its impact on quality of life, as well as its social impact at school and at the workplace. However, AR with or without asthma is a huge economic burden. Thus, there was clearly a need for a global evidence-based document which would highlight the interactions between the upper and lower airways including diagnosis, epidemiology, common risk factors, management and prevention. The Allergic Rhinitis and its Impact on Asthma (ARIA) document was first published in 2001 as a state-of-the-art guideline for the specialist, the general practitioner and other health care professionals. Subsequent new evidence regarding the pathomechanisms, new drugs and increased knowledge have resulted in the publication of the ARIA 2008 update. The present review summarizes the ARIA update with particular emphasis on the current status of AR and asthma in the Asia-Pacific region and discusses the Western and Asian perspective.

  15. Deposition velocities to Sorbus aria, Acer campestre, Populus deltoides x trichocarpa 'Beaupre', Pinus nigra and x Cupressocyparis leylandii for coarse, fine and ultra-fine particles in the urban environment

    International Nuclear Information System (INIS)

    Freer-Smith, P.H.; Beckett, K.P.; Taylor, Gail

    2005-01-01

    Trees are effective in the capture of particles from urban air to the extent that they can significantly improve urban air quality. As a result of their aerodynamic properties conifers, with their smaller leaves and more complex shoot structures, have been shown to capture larger amounts of particle matter than broadleaved trees. This study focuses on the effects of particle size on the deposition velocity of particles (Vg) to five urban tree species (coniferous and broadleaved) measured at two field sites, one urban and polluted and a second more rural. The larger uptake to conifers is confirmed, and for broadleaves and conifers Vg values are shown to be greater for ultra-fine particles (Dp<1.0 μm) than for fine and coarse particles. This is important since finer particles are more likely to be deposited deep in the alveoli of the human lung causing adverse health effects. The finer particle fraction is also shown to be transported further from the emission source; in this study a busy urban road. In further sets of data the aqueous soluble and insoluble fractions of the ultra-fines were separated, indicating that aqueous insoluble particles made up only a small proportion of the ultra-fines. Much of the ultra-fine fraction is present as aerosol. Chemical analysis of the aqueous soluble fractions of coarse, fine and ultra-fine particles showed the importance of nitrates, chloride and phosphates in all three size categories at the polluted and more rural location

  16. NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)

    DEFF Research Database (Denmark)

    Broholm, Sofie L.; Gramsbergen, Simone; Nyberg, Nils

    Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to control postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood g...... a 1H-NMR method suitable for NMR-based metabolomics...

  17. Resumen ejecutivo de ARIA 2016: vías integradas de atención para la medicina predictiva a lo largo del ciclo de vida en Argentina

    NARCIS (Netherlands)

    Ivancevich, Juan Carlos; Neffen, Hugo; Zernotti, Mario E.; Asayag, Estrella; Blua, Ariel; Cicerán, Alberto; Jares, Edgardo J.; Lavrut, Alberto J.; Máspero, Jorge F.; Agache, Ioana; Bachert, Claus; Bedbrook, Anna; Canonica, Giorgio W.; Casale, Thomas B.; Cruz, Álvaro A.; Fokkens, Wytske J.; Hellings, Peter W.; Samolinski, Boleslaw; Bousquet, Jean

    2017-01-01

    The ARIA initiative was started during a World Health Organization workshop in 1999. The initial goals were to propose a new classification for allergic rhinitis, to promote the concept of multi-morbidity in asthma and rhinitis and to develop guidelines with stakeholders for world-wide use. ARIA is

  18. Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper

    NARCIS (Netherlands)

    Bousquet, Jean; Schünemann, H. J.; Zuberbier, T.; Bachert, C.; Baena-Cagnani, C. E.; Bousquet, P. J.; Brozek, J.; Canonica, G. W.; Casale, T. B.; Demoly, P.; Gerth van Wijk, R.; Ohta, K.; Bateman, E. D.; Calderon, M.; Cruz, A. A.; Dolen, W. K.; Haughney, J.; Lockey, R. F.; Lötvall, J.; O'Byrne, P.; Spranger, O.; Togias, A.; Bonini, S.; Boulet, L. P.; Camargos, P.; Carlsen, K. H.; Chavannes, N. H.; Delgado, L.; Durham, S. R.; Fokkens, W. J.; Fonseca, J.; Haahtela, T.; Kalayci, O.; Kowalski, M. L.; Larenas-Linnemann, D.; Li, J.; Mohammad, Y.; Mullol, J.; Naclerio, R.; O'Hehir, R. E.; Papadopoulos, N.; Passalacqua, G.; Rabe, K. F.; Pawankar, R.; Ryan, D.; Samolinski, B.; Simons, F. E. R.; Valovirta, E.; Yorgancioglu, A.; Yusuf, O. M.; Agache, I.; Aït-Khaled, N.; Annesi-Maesano, I.; Beghe, B.; Ben Kheder, A.; Blaiss, M. S.; Boakye, D. A.; Bouchard, J.; Burney, P. G.; Busse, W. W.; Chan-Yeung, M.; Chen, Y.; Chuchalin, A. G.; Costa, D. J.; Custovic, A.; Dahl, R.; Denburg, J.; Douagui, H.; Emuzyte, R.; Grouse, L.; Humbert, M.; Jackson, C.; Johnston, S. L.; Kaliner, M. A.; Keith, P. K.; Kim, Y. Y.; Klossek, J. M.; Kuna, P.; Le, L. T.; Lemiere, C.; Lipworth, B.; Mahboub, B.; Malo, J. L.; Marshall, G. D.; Mavale-Manuel, S.; Meltzer, E. O.; Morais-Almeida, M.; Motala, C.; Naspitz, C.; Nekam, K.; Niggemann, B.; Nizankowska-Mogilnicka, E.; Okamoto, Y.; Orru, M. P.; Ouedraogo, S.; Palkonen, S.; Popov, T. A.; Price, D.; Rosado-Pinto, J.; Scadding, G. K.; Sooronbaev, T. M.; Stoloff, S. W.; Toskala, E.; van Cauwenberge, P.; Vandenplas, O.; van Weel, C.; Viegi, G.; Virchow, J. C.; Wang, D. Y.; Wickman, M.; Williams, D.; Yawn, B. P.; Zar, H. J.; Zernotti, M.; Zhong, N.

    2010-01-01

    The links between asthma and rhinitis are well characterized. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines stress the importance of these links and provide guidance for their prevention and treatment. Despite effective treatments being available, too few patients receive

  19. The ARIA score of allergic rhinitis using mobile technology correlates with quality-of-life

    DEFF Research Database (Denmark)

    Bousquet, J; Arnavielhe, S; Bedbrook, A

    2018-01-01

    Mobile technology has been used to appraise allergic rhinitis control but more data are needed. In order to better assess the importance of mobile technologies in rhinitis control, the ARIA (Allergic Rhinitis and its Impact on Asthma) score ranging from 0 to 4 of the Allergy Diary was compared wi...

  20. Pollen flora of pakistan-lxxi. rosaceae

    International Nuclear Information System (INIS)

    Perveen, A.; Qaiser, M.

    2014-01-01

    Pollen morphology of 50 species representing 17 genera of the family Rosaceae i.e., Alchemilla, Argimonia, Cotoneaster, Crataegus, Duchesnea, Fragaria, Eriybotyra, Filipandula, Geum, Malus, Prunus, Potentilla, Pyrus , Rosa, Sibbaldia, Sorbaria and Sorbus has been studied from Pakistan by light and scanning electron microscope. Pollen grains are usually free, radially symmetrical, isopolar, prolate-spheroidal to subprolate or oblate-spheroidal rarely perprolate, tricolporate rarely tricolpate. Tectum mostly coarsely-finely striate, rarely striate-rugulate, scabrate or spinulose often reticulate. Rosaceae is more or less eurypalynous family. Significant variation is found in P/E ratio, shape and exine ornamentation and on the basis of these characters family has been divided into seven pollen types viz., Agrimonia eupatoria-type, Alchemilla ypsilotoma-type, Cotoneaster affinis-type, Fragaria nubicola-type, Geum roylei-type, Malus pumila-type, Potentilla pamirica-type. Pollen data is useful at specific and generic level. (author)

  1. Post-dispersal seed predation of woody forest species limits recolonization of forest plantations on ex-arable land

    DEFF Research Database (Denmark)

    Bruun, Hans Henrik; Valtinat, Karin; Kollmann, Johannes

    2010-01-01

    be differences in recruitment. The present study addresses post-dispersal seed predation, mainly of woody plants, as the factor limiting the recolonization of young oak plantations in southern Sweden. Our objectives were to investigate differences in dispersal and post-dispersal seed predation between first......, the colonization of forest plantations by native shrubs and trees appears to be habitat-limited; the only exception being Rhamnus catharticus, for which poor dispersal ability may be more important. Post-dispersal seed predation of forest shrubs and trees was marked, especially in relatively small and isolated...... plantations on ex-arable land. There was a high seed predation of Crataegus monogyna, Sorbus aucuparia and Viburnum opulus on ex-arable land, while that of Frangula alnus and Sambucus racemosa was not associated with site placement and land-use history. Seed predation is probably a more important factor...

  2. Distribution of enantiomers of volatile organic compounds in selected fruit distillates.

    Science.gov (United States)

    Vyviurska, Olga; Zvrškovcová, Helena; Špánik, Ivan

    2017-01-01

    The enantiomer ratios of chiral volatile organic compounds in fruit distillates were determined by multidimensional gas chromatography using solid-phase microextraction (SPME) as a sample treatment procedure. Linalool and its oxides, limonene, α-terpineol, and nerolidol, were present at the highest concentration levels, while significantly lower amounts of β-citronellol and lactones were found in the studied samples. However, almost all terpenoids mainly occur as a racemic or near-racemic mixture; enantiomer distribution of some chiral organic compounds in fruit distillates correlated to a botanical origin. In particular, a significant enantiomeric excess of (R)-linalool and (S)-α-terpineol was found only for pear brandy, and likewise the dominance (R)-limonene and the second eluted enantiomer of nerolidol for Sorbus domestica and strawberry, respectively. The distribution of γ-lactones stereoisomers was more nonspecific, with a general excess of the R-enantiomer. © 2016 Wiley Periodicals, Inc.

  3. Del libro de las polémicas: Bernardo Arias Trujillo y Guillermo Valencia

    Directory of Open Access Journals (Sweden)

    Vicente Pérez Silva

    1979-10-01

    Full Text Available Como le aconteciera a nuestro amo y señor don Quijote de la Mancha, el maestro Guillermo Valencia -su afortunado pariente- emprende la tercera salida por los predios de la controversia literaria. En esta vez, lanza en ristre, lo hace en defensa de la violenta arremetida que le endilgara Bernardo Arias Trujillo con motivo de la traducción de la Balada de la Cárcel de Reading.

  4. Verification of Advective Bar Elements Implemented in the Aria Thermal Response Code.

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Brantley [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-01-01

    A verification effort was undertaken to evaluate the implementation of the new advective bar capability in the Aria thermal response code. Several approaches to the verification process were taken : a mesh refinement study to demonstrate solution convergence in the fluid and the solid, visually examining the mapping of the advective bar element nodes to the surrounding surfaces, and a comparison of solutions produced using the advective bars for simple geometries with solutions from commercial CFD software . The mesh refinement study has shown solution convergence for simple pipe flow in both temperature and velocity . Guidelines were provided to achieve appropriate meshes between the advective bar elements and the surrounding volume. Simulations of pipe flow using advective bars elements in Aria have been compared to simulations using the commercial CFD software ANSYS Fluent (r) and provided comparable solutions in temperature and velocity supporting proper implementation of the new capability. Verification of Advective Bar Elements iv Acknowledgements A special thanks goes to Dean Dobranich for his guidance and expertise through all stages of this effort . His advice and feedback was instrumental to its completion. Thanks also goes to Sam Subia and Tolu Okusanya for helping to plan many of the verification activities performed in this document. Thank you to Sam, Justin Lamb and Victor Brunini for their assistance in resolving issues encountered with running the advective bar element model. Finally, thanks goes to Dean, Sam, and Adam Hetzler for reviewing the document and providing very valuable comments.

  5. Rapid Response Products of The ARIA Project for the M6.0 August 24, 2014 South Napa Earthquake

    Science.gov (United States)

    Yun, S. H.; Owen, S. E.; Hua, H.; Milillo, P.; Fielding, E. J.; Hudnut, K. W.; Dawson, T. E.; Mccrink, T. P.; Jo, M. J.; Barnhart, W. D.; Manipon, G. J. M.; Agram, P. S.; Moore, A. W.; Jung, H. S.; Webb, F.; Milillo, G.; Rosinski, A.

    2014-12-01

    A magnitude 6.0 earthquake struck southern Napa county northeast of San Francisco, California, on Aug. 24, 2014, causing significant damage in the city of Napa and nearby areas. One day after the earthquake, the Advanced Rapid Imaging and Analysis (ARIA) team produced and released observations of coseismic ground displacement measured with continuous GPS stations of the Plate Boundary Observatory (operated by UNAVCO for the National Science Foundation) and the Bay Area Rapid Deformation network (operated by Berkeley Seismological Laboratory). Three days after the earthquake (Aug. 27), the Italian Space Agency's (ASI) COSMO-SkyMed (CSK) satellite acquired their first post-event data. On the same day, the ARIA team, in collaboration with ASI and University of Basilicata, produced and released a coseismic interferogram that revealed ground deformation and surface rupture. The depiction of the surface rupture - discontinuities of color fringes in the CSK interferogram - helped guide field geologists from the US Geological Survey and the California Geological Survey (CGS) to features that may have otherwise gone undetected. Small-scale cracks were found on a runway of the Napa County Airport, as well as bridge damage and damaged roads. ARIA's response to this event highlighted the importance of timeliness for mapping surface deformation features. ARIA's rapid response products were shared through Southern California Earthquake Center's response website and the California Earthquake Clearinghouse. A damage proxy map derived from InSAR coherence of CSK data was produced and distributed on Aug. 27. Field crews from the CGS identified true and false positives, including mobile home damage, newly planted grape vines, and a cripple wall failure of a house. Finite fault slip models constrained from CSK interferograms and continuous GPS observations reveal a north-propagating rupture with well-resolved slip from 0-10.5 km depth. We also measured along-track coseismic

  6. ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

    NARCIS (Netherlands)

    J. Bousquet (Jean); P.W. Hellings (Peter); I. Agache; A. Bedbrook (A.); C. Bachert (Claus); K.-C. Bergmann (Karl-Christian); Bewick, M.; C. Bindslev-Jensen; Bosnic-Anticevitch, S.; Bucca, C.; Caimmi, D.P.; P. Camargos; G. Canonica (Gwalter); T.B. Casale (Thomas); N.H. Chavannes (Nicolas); A.A. Cruz; De Carlo, G.; R. Dahl; P. Demoly; Devillier, P.; J. Fonseca; W.J. Fokkens (Wytske); Guldemond, N.A.; T. Haahtela (Tari); Illario, M.; P.M. Just; M. Keil (Mark); L. Klimek (Ludger); P. Kuna; D. Larenas-Linnemann (Désirée); M. Morais-Almeida; Mullol, J.; Murray, R.; R. Naclerio; R.E. O'hehir; N. Papadopoulos; R. Pawankar (Ruby); Potter, P.; D. Ryan (Dermot); Samolinski, B.; H.J. Schünemann (Holger); A. Sheikh (Aziz); F.E.R. Simons; Stellato, C.; A. Todo Bom; Tomazic, P.V.; A. Valiulis (Arunas); E. Valovirta (Erkka); Ventura, M.T.; M. Wickman (Magnus); Young, I.; A. Yorgancioglu; T. Zuberbier (Torsten); W. Aberer (W.); C.A. Akdis; C.A. Akdis; I. Annesi-Maesano; Ankri, J.; I.J. Ansotegui (I.); J.M. Antó (Josep M.); Arnavielhe, S.; Asarnoj, A.; Arshad, H.; Avolio, F.; I. Baiardini (Ilaria); Barbara, C.; Barbagallo, M.; E.D. Bateman (Eric); B. Beghe; E.H. Bel; K.S. Bennoor (K.); Benson, M.; Białoszewski, A.Z.; T. Bieber (Thomas); L. Bjermer (Leif); Blain, H.; F. Blasi (Francesco); A.L. Boner; M. Bonini (Matteo); S. Bonini (Sergio); Bosse, I.; J. Bouchard (Jacques); L.P. Boulet; Bourret, R.; J. Bousquet (Jean); F. Braido (Fulvio); A. Briggs (Andrew); C.E. Brightling (C.); J. Brozek; Buhl, R.; Bunu, C.; Burte, E.; A. Bush (Andrew); Caballero-Fonseca, F.; M. Calderon (Moises); Camuzat, T.; D. Cardona (Doris); Carreiro-Martins, P.; Carriazo, A.M.; K.H. Carlsen (Karin); W.W. Carr (Warner); Cepeda Sarabia, A.M.; Cesari, M.; L. Chatzi (Leda); Chiron, R.; Chivato, T.; Chkhartishvili, E.; A.G. Chuchalin; Chung, K.F.; G. Ciprandi (G.); De Sousa, J.C. (J. Correia); L. Cox (Linda); Crooks, G.; A. Custovic; S.E. Dahlen; U. Darsow (U.); Dedeu, T.; D. Deleanu (D.); J. Denburg; De Vries, G.; Didier, A.; Dinh-Xuan, A.T.; D. Dokic (D.); H. Douagui; Dray, G.; R. Dubakiene (R.); S.R. Durham (Stephen); G. Du Toit (George); Dykewicz, M.S.; Eklund, P.; Y. El-Gamal (Y.); Ellers, E.; R. Emuzyte; Farrell, J.; A. Fink-Wagner (A.); A. Fiocchi (Alessandro); M. Fletcher (M.); Forastiere, F.; M. Gaga (Mina); A. Gamkrelidze (Amiran); Gemicioǧlu, B.; J.E. Gereda (J.); Van Wick, R.G. (R. Gerth); S. González Diaz (S.); Grisle, I.; L. Grouse; Gutter, Z.; M.A. Guzmán (M.); B. Hellquist-Dahl (B.); J. Heinrich (Joachim); Horak, F.; J.O.B. Hourihane; Humbert, M.; Hyland, M.; Iaccarino, G.; Jares, E.J.; Jeandel, C.; S.L. Johnston; G.F. Joos (Guy); Jonquet, O.; Jung, K.S.; M. Jutel (M.); Kaidashev, I.; Khaitov, M.; O. Kalayci; A.F. Kalyoncu (A.); Kardas, P.; P.K. Keith; M. Kerkhof (Marjan); H.A.M. Kerstjens (Huib); N. Khaltaev; M. Kogevinas (Manolis); Kolek, V.; G.H. Koppelman (Gerard); M.L. Kowalski; Kuitunen, M.; C.A. Kull (Christian); V. Kvedariene (V.); B.N.M. Lambrecht (Bart); S. Lau (Susanne); Laune, D.; L.T. Le; A.P. Lieberman (Andrew); B. Lipworth; J. Li (J.); K.C. Lødrup Carlsen (K. C.); R. Louis (Renaud); Lupinek, C.; W. MacNee; Magar, Y.; Magnan, A.; B. Mahboub; Maier, D.; Majer, I.; Malva, J.; Manning, P.; De Manuel Keenoy, E.; G.D. Marshall; M.R. Masjedi (M.); Mathieu-Dupas, E.; Maurer, M.; S. Mavale-Manuel; E. Melén (Erik); Melo-Gomes, E.; E.O. Meltzer; Mercier, J.; J. Merk (Jeroen); Miculinic, N.; F. Mihaltan (F.); B. Milenkovic (Branislava); Millot-Keurinck, J.; Y. Mohammad; I. Momas (I.); R. Mösges; Muraro, A.; L. Namazova-Baranova (L.); R. Nadif (Rachel); Neffen, H.; Nekam, K.; A. Nieto (Antonio); B. Niggemann; Nogueira-Silva, L.; Nogues, M.; T.D. Nyembue (T.); K. Ohta; Y. Okamoto; Okubo, K.; Olive-Elias, M.; S. Ouedraogo; P. Paggiaro (Pierluigi); I. Pali-Schöll (I.); S. Palkonen; P. Panzner (P.); Papi, A.; Park, H.S.; G. Passalacqua (Giovanni); S.E. Pedersen (Soren E.); Pereira, A.M.; O. Pfaar (Oliver); Picard, R.; B. Pigearias (B.); I. Pin (Isabelle); Plavec, D.; Pohl, W.; T.A. Popov; Portejoie, F.; D.S. Postma (Dirkje); L.K. Poulsen; D. Price (David); K.F. Rabe (Klaus F.); Raciborski, F.; G. Roberts; Robalo-Cordeiro, C.; Rodenas, F.; L. Rodríguez-Mañas (Leocadio); Rolland, C.; M. Roman Rodriguez (M.); A. Romano; J. Rosado-Pinto; K. Rosario (Karyna); Rottem, M.; M. Sanchez-Borges; Sastre-Dominguez, J.; G.K. Scadding; Scichilone, N.; P. Schmid-Grendelmeier (Peter); Serrano, E.; M.D. Shields; V. Siroux (V.); J.C. Sisul (J.); Skrindo, I.; H.A. Smit (Henriëtte); D. Solé (D.); Sooronbaev, T.; O. Spranger; Stelmach, R.; P.J. Sterk (Peter); Strandberg, T.; J. Sunyer (Jordi); C. Thijs (Carel); M. Triggiani (M.); R. Valenta; A.L. Valero (A.); Van Eerd, M.; Van Ganse, E.; Van Hague, M.; O. Vandenplas (Olivier); Varona, L.L.; Vellas, B.; Vezzani, G.; Vazankari, T.; G. Viegi; Vontetsianos, T.; Wagenmann, M.; Walker, S.; D.Y. Wang (De Yun); U. Wahn (Ulrich); Werfel, T.; Whalley, B.; D. Williams; Williams, S.; Wilson, N.; J. Wright (Juliet); B.P. Yawn (Barbara); P.K. Yiallouros (P.); O.M. Yusuf (Osman); Zaidi, A.; H.J. Zar; M. Zernotti; Zhang, L.; Zhong, N.; M. Zidarn (M.)

    2016-01-01

    textabstractThe Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to

  7. Estimation of the proportion of some elements and their distribution on a surface of thallus of lichenized fungus Xanthoria parietina (L. Th. Fr. using sample-nondestructive μ-XRF spectrometer M4 Tornado

    Directory of Open Access Journals (Sweden)

    Biazrov Lev Georgievich

    2013-10-01

    Full Text Available The composition of 19 elements - Al, Si, P, S, Cl, K, Ca, Ti, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Sr, Ba, Pb - were compared in the peripheral (younger and central (older parts of the upper surface of the epiphytic lichen Xanthoria parietina thallus from the bark of Sorbus aucuparia in Moscow city using sample-nondestructive μ-XRF spectrometer. This species is often used in biomonitoring of air quality. The results showed that the elements content was highly variable. Mean values of atomic percent of Fe, Co, Zn, and Pb were statistically higher in the central part of the upper surface, while P, S, Cl, K, Ca, and Mn were higher in the peripheral part. Differences between other elements were not statistically valid, but there is a trend to greater maintenance of the majority of the elements on the surface of the central part of the thallus. Mapping the distribution of some elements on the part of the thallus surface is presented.

  8. Tree and shrub expansion over the past 34 years at the tree-line near Abisko, Sweden.

    Science.gov (United States)

    Rundqvist, Sara; Hedenås, Henrik; Sandström, Anneli; Emanuelsson, Urban; Eriksson, Håkan; Jonasson, Christer; Callaghan, Terry V

    2011-09-01

    Shrubs and trees are expected to expand in the sub-Arctic due to global warming. Our study was conducted in Abisko, sub-arctic Sweden. We recorded the change in coverage of shrub and tree species over a 32- to 34-year period, in three 50 x 50 m plots; in the alpine-tree-line ecotone. The cover of shrubs and trees (tree stems (> or =3.5 cm) were noted and positions determined. There has been a substantial increase of cover of shrubs and trees, particularly dwarf birch (Betula nana), and mountain birch (Betula pubescens ssp. czerepanovii), and an establishment of aspen (Populus tremula). The other species willows (Salix spp.), juniper (Juniperus communis), and rowan (Sorbus aucuparia) revealed inconsistent changes among the plots. Although this study was unable to identify the causes for the change in shrubs and small trees, they are consistent with anticipated changes due to climate change and reduced herbivory.

  9. Arias Montano, traductor: filosofía, técnicas y praxis multilingüe

    OpenAIRE

    Fernández Marcos, Natalio; Fernández Tejero, Emilia

    2012-01-01

    Arias Montano was one of the best orientalists of the 16th century. He is specially known as editor of the Antwerp Polyglot. He translated into Latin several originals of this Polyglot, and in his Biblical commentaries he provided a new translation for most of the passages. He was in favour of a literal translation and he even dared to correct Sanctes Pagnino’s Latin version. In his Biblical commentaries he utilized idioms of the European languages of his time, especially Castilian. In this a...

  10. Las dos versiones de la De Psalterii Anglicani exemplari animaduersio de Benito Arias Montano en la Biblia Políglota de Amberes

    Directory of Open Access Journals (Sweden)

    Dávila Pérez, Antonio

    2014-06-01

    Full Text Available In the eighth and final volume of the Antwerp Polyglot Arias Montano published a short text titled De Psalterii Anglicani Exemplari Animaduersio. In his defense of the Hebrew original of the Old Testament, Montano set out to warn the reader that some of the more esteemed manuscripts by the so-called Hebrew-haters of his time were of little value. For this purpose, Arias Montano examined a Hebrew manuscript of the Psalter considered to be of particular antiquity and significance by the powerful bishop Wilhelm D. Lindanus, and concluded that it was in fact recent and quite worthless in many aspects, thereby fiercely attacking the latter’s scholarly reputation. This attack, based in part on a false accusation, was the beginning of a scholarly controversy lasting over fifteen years. The present essay calls attention to the fact that two versions of the Animaduersio, very different from each other, can be found in surviving copies of the Polyglot Bible. In order to illuminate the circumstances that led to these versions, the author proposes a threefold goal: (1 to gather the Latin text and the Spanish translation of the two versions of the Animaduersio; (2 to examine the reasons why Arias Montano rewrote his text in the light of the private correspondence of both scholars; (3 and to propose an approximate date for each of the versions.En el octavo y último volumen de la Biblia Regia de Amberes Benito Arias Montano publicaba un breve texto titulado De Psalterii Anglicani exemplari animaduersio. En el marco de su defensa del original hebreo del Antiguo Testamento, su autor consideraba necesario advertir al lector de que algunos de los manuscritos más apreciados por los llamados «misohebreos» de su tiempo carecían de todo valor. Para ello, Arias Montano examinó un manuscrito hebreo del salterio elogiado como muy antiguo y relevante por el poderoso obispo Guillermo D. Lindano, y concluía que el códice era reciente y de escaso valor, cargando de

  11. Implementation of a PETN failure model using ARIA's general chemistry framework

    Energy Technology Data Exchange (ETDEWEB)

    Hobbs, Michael L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-01-01

    We previously developed a PETN thermal decomposition model that accurately predicts thermal ignition and detonator failure [1]. This model was originally developed for CALORE [2] and required several complex user subroutines. Recently, a simplified version of the PETN decomposition model was implemented into ARIA [3] using a general chemistry framework without need for user subroutines. Detonator failure was also predicted with this new model using ENCORE. The model was simplified by 1) basing the model on moles rather than mass, 2) simplifying the thermal conductivity model, and 3) implementing ARIA’s new phase change model. This memo briefly describes the model, implementation, and validation.

  12. MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation.

    Science.gov (United States)

    Bousquet, J; Schunemann, H J; Fonseca, J; Samolinski, B; Bachert, C; Canonica, G W; Casale, T; Cruz, A A; Demoly, P; Hellings, P; Valiulis, A; Wickman, M; Zuberbier, T; Bosnic-Anticevitch, S; Bedbrook, A; Bergmann, K C; Caimmi, D; Dahl, R; Fokkens, W J; Grisle, I; Lodrup Carlsen, K; Mullol, J; Muraro, A; Palkonen, S; Papadopoulos, N; Passalacqua, G; Ryan, D; Valovirta, E; Yorgancioglu, A; Aberer, W; Agache, I; Adachi, M; Akdis, C A; Akdis, M; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Baiardini, I; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Bel, E H; Ben Kheder, A; Bennoor, K S; Benson, M; Bewick, M; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Boner, A L; Boulet, L P; Bonini, M; Bonini, S; Bosse, I; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Calderon, M A; Camargos, P A M; Camuzat, T; Carlsen, K H; Carr, W; Cepeda Sarabia, A M; Chavannes, N H; Chatzi, L; Chen, Y Z; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Ciprandi, G; Cirule, I; Correia de Sousa, J; Cox, L; Crooks, G; Costa, D J; Custovic, A; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fink Wagner, A; Fletcher, M; Fiocchi, A; Forastiere, F; Gamkrelidze, A; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grouse, L; Guzmán, M A; Haahtela, T; Hellquist-Dahl, B; Heinrich, J; Horak, F; Hourihane, J O 'b; Howarth, P; Humbert, M; Hyland, M E; Ivancevich, J C; Jares, E J; Johnston, S L; Joos, G; Jonquet, O; Jung, K S; Just, J; Kaidashev, I; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Khaltaev, N; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J; Louis, R; Magard, Y; Magnan, A; Mahboub, B; Majer, I; Makela, M J; Manning, P; De Manuel Keenoy, E; Marshall, G D; Masjedi, M R; Maurer, M; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Merk, H; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Mösges, R; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Palmer, S; Panzner, P; Papi, A; Park, H S; Pavord, I; Pawankar, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Pohl, W; Popov, T A; Portejoie, F; Postma, D; Potter, P; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Robalo-Cordeiro, C; Rolland, C; Rosado-Pinto, J; Reitamo, S; Rodenas, F; Roman Rodriguez, M; Romano, A; Rosario, N; Rosenwasser, L; Rottem, M; Sanchez-Borges, M; Scadding, G K; Serrano, E; Schmid-Grendelmeier, P; Sheikh, A; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H A; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Strandberg, T; Sunyer, J; Thijs, C; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; van Hage, M; Vandenplas, O; Vezzani, G; Vichyanond, P; Viegi, G; Wagenmann, M; Walker, S; Wang, D Y; Wahn, U; Williams, D M; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zar, H J; Zernotti, M E; Zhang, L; Zhong, N; Zidarn, M; Mercier, J

    2015-11-01

    Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) is a simple system centred around the patient which was devised to fill many of these gaps using Information and Communications Technology (ICT) tools and a clinical decision support system (CDSS) based on the most widely used guideline in allergic rhinitis and its asthma comorbidity (ARIA 2015 revision). It is one of the implementation systems of Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA). Three tools are used for the electronic monitoring of allergic diseases: a cell phone-based daily visual analogue scale (VAS) assessment of disease control, CARAT (Control of Allergic Rhinitis and Asthma Test) and e-Allergy screening (premedical system of early diagnosis of allergy and asthma based on online tools). These tools are combined with a clinical decision support system (CDSS) and are available in many languages. An e-CRF and an e-learning tool complete MASK. MASK is flexible and other tools can be added. It appears to be an advanced, global and integrated ICT answer for many unmet needs in allergic diseases which will improve policies and standards. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Observations of the neutral atmosphere between 100 and 200 km using ARIA rocket-borne and ground-based instruments

    International Nuclear Information System (INIS)

    Hecht, J.H.; Christensen, A.B.; Gutierrez, D.J.

    1995-01-01

    The atmospheric response in the aurora (ARIA) rocket was launched at 1406 UT on March 3, 1992, from Poker Flat, Alaska, into a pulsating diffuse aurora; rocket-borne instruments included an eight-channel photometer, a far ultraviolet spectrometer, a 130.4-nm atomic oxygen resonance lamp, and two particle spectrometers covering the energy range of 1-400 eV and 10 eV to 20 keV. The photometer channels were isolated using narrow-band interference filters and included measurements of the strong permitted auroral emissions N 2 (337.1 nm), N 2 + (391.4 nm), and O I (844.6 nm). A ground-based photometer measured the premitted N 2 + (427.8 nm), the forbidden O I (630.0 nm), and the premitted O I (844.6 nm) emissions. The ground-based instrument was pointed in the magnetic zenith. Also, the rocket payload was pointed in the magnetic zenith from 100 to 200 km on the upleg. The data were analyzed using the Strickland electron transport code, and the rocket and ground-based results were found to be in good agreement regarding the inferred characteristic energy of the precipitating auroral flux and the composition of the neutral atmosphere during the rocket flight. In particular, it was found that the O/N 2 density ratio in the neutral atmosphere diminished during the auroral substorm, which started about 2 hours before the ARIA rocket flight. The data showed that there was about a 10-min delay between the onset of the substorm and the decrease of the O/N 2 density ratio. At the time of the ARIA flight this ratio had nearly returned to its presubstorm value. However, the data also showed that the O/N 2 density ratio did not recover to its presubstorm value until nearly 30 min after the particle and joule heating had subsided. Both the photometer and oxygen densities in the region above 130 km. The observed auroral brightness ratio B 337.1 /B 391.4 equaled 0.29 and was in agreement with other recent measurements

  14. The Advanced Rapid Imaging and Analysis (ARIA) Project: Status of SAR products for Earthquakes, Floods, Volcanoes and Groundwater-related Subsidence

    Science.gov (United States)

    Owen, S. E.; Yun, S. H.; Hua, H.; Agram, P. S.; Liu, Z.; Sacco, G. F.; Manipon, G.; Linick, J. P.; Fielding, E. J.; Lundgren, P.; Farr, T. G.; Webb, F.; Rosen, P. A.; Simons, M.

    2017-12-01

    The Advanced Rapid Imaging and Analysis (ARIA) project for Natural Hazards is focused on rapidly generating high-level geodetic imaging products and placing them in the hands of the solid earth science and local, national, and international natural hazard communities by providing science product generation, exploration, and delivery capabilities at an operational level. Space-based geodetic measurement techniques including Interferometric Synthetic Aperture Radar (InSAR), differential Global Positioning System, and SAR-based change detection have become critical additions to our toolset for understanding and mapping the damage and deformation caused by earthquakes, volcanic eruptions, floods, landslides, and groundwater extraction. Up until recently, processing of these data sets has been handcrafted for each study or event and has not generated products rapidly and reliably enough for response to natural disasters or for timely analysis of large data sets. The ARIA project, a joint venture co-sponsored by the California Institute of Technology and by NASA through the Jet Propulsion Laboratory, has been capturing the knowledge applied to these responses and building it into an automated infrastructure to generate imaging products in near real-time that can improve situational awareness for disaster response. In addition to supporting the growing science and hazard response communities, the ARIA project has developed the capabilities to provide automated imaging and analysis capabilities necessary to keep up with the influx of raw SAR data from geodetic imaging missions such as ESA's Sentinel-1A/B, now operating with repeat intervals as short as 6 days, and the upcoming NASA NISAR mission. We will present the progress and results we have made on automating the analysis of Sentinel-1A/B SAR data for hazard monitoring and response, with emphasis on recent developments and end user engagement in flood extent mapping and deformation time series for both volcano

  15. De divinações xamânicas e acusações de feitiçaria: imagens Wauja da agência letal

    Directory of Open Access Journals (Sweden)

    Aristóteles Barcelos Neto

    2006-10-01

    Full Text Available O artigo explora as diferenças e as relações entre feitiçaria e xamanismo entre os Wauja do Alto Xingu com ênfases nos processos de transformações corporais, nas noções de agência letal e na ontologia da predação. A feitiçaria é descrita como uma categoria de acusação de assassinato e de responsabilidade por malefícios de diversas ordens e como um dispositivo de contrapoder no cenário de chefias fortes e relativamente autoritárias. As acusações, sobretudo as de assassinato, tecem uma urdidura política que traz a feitiçaria para o centro da socialidade wauja. A hipótese principal é a de que a feitiçaria tenha um duplo efeito político, simultâneo ou sucessivo, na paisagem sociológica wauja: ela pode servir para perseguir, eliminar ou exilar os adversários de um chefe, bem como pode se voltar contra este para contestar seu status e comprometer seu prestígio. Tem também um duplo sentido estético: é a encarnação mais perfeita da fealdade e da tristeza-morte, por isso, profundamente oposta ao ritual e à matéria própria das realizações terapêuticas que caracterizam o xamanismo xinguano.This article discusses the differences and relations between witchcraft and shamanism among the Wauja Indians of the Upper Xingu river, focusing on the processes of body transformations, notions of lethal agency and the ontology of predation. Witchcraft is described as an accusation category referencing murder and also as an anti-power apparatus in the context of strong and relatively authoritarian chieftainships. Accusations, especially those of murder, weave a political plot that brings witchcraft to the center of Wauja sociality. Our main hypothesis is that witchcraft has a double political effect (simultaneous or successive in the Wauja sociological landscape: it can serve to persecute, eliminate, or exile a chief’s adversaries, but it also may turn against a chief, compromising his prestige and contesting his status

  16. Results of growing relatively smoke resistant types of trees and their practical use. [German Democratic Republic

    Energy Technology Data Exchange (ETDEWEB)

    Tzschacksch, O.

    1985-01-01

    Achievements in cultivating sulfur dioxide resistant conifers in the German Democratic Republic are summarized. These conifers will be planted in afforestation programs in smoke damage zones I, i.e. in conifer forests at high elevations with maximum pollution damage. Nurseries with the most promising tree types have been established for harvesting seeds for propagation. Cultivation of cuttings and tree grafting is carried out in experimental nurseries along with laboratory gas treatment tests. Smoke resistant varieties of the common spruce Picae abies (L.) show vigorous growth in smoke damage zone I. Other spruce types suitable for cultivation are Picea pungens Engelm., Picea omorica (Panc.) Purk. with the highest vitality in 15 to 20 year old trial plantings in smoke damage zone I extreme, and Picea glanca, rubens and orientalis. Suitable pines are Pinus contorta Dougl. ex Loud. (Murray pine), Pinus mugo Turra, and others; resistant larches are Larix decidua and Larix leptolepis. Deciduous trees being cultivated for afforestation are aspens (Populus tremula L.) and mountain ash (Sorbus aucuparia L.). 11 references.

  17. Use of Aria to simulate laser weld pool dynamics for neutron generator production.

    Energy Technology Data Exchange (ETDEWEB)

    Noble, David R.; Notz, Patrick K.; Martinez, Mario J.; Kraynik, Andrew Michael

    2007-09-01

    This report documents the results for the FY07 ASC Integrated Codes Level 2 Milestone number 2354. The description for this milestone is, 'Demonstrate level set free surface tracking capabilities in ARIA to simulate the dynamics of the formation and time evolution of a weld pool in laser welding applications for neutron generator production'. The specialized boundary conditions and material properties for the laser welding application were implemented and verified by comparison with existing, two-dimensional applications. Analyses of stationary spot welds and traveling line welds were performed and the accuracy of the three-dimensional (3D) level set algorithm is assessed by comparison with 3D moving mesh calculations.

  18. Aportación a la farmacoterapia del siglo XVIII: el recetario médico de Anselmo Arias Teixeiro

    Directory of Open Access Journals (Sweden)

    Álvarez Soaje, Miguel

    2015-12-01

    Full Text Available Among a number of eighteen century manuscripts attributed to Anselmo Arias Teixeiro we had located the document presented in this research, a heterogeneous set of recipes aimed at a public with low income. It is a relatively common type of work throughout the century, whereby, its author based on some popular editions which circulate with relative success despite its limitations from a therapeutic point of view. The manuscript, which we present entirely helps to see the therapeutic of eighteenth century from a different perspective away from medical treatises or the official pharmacopoeia that characterize the new enlightened science.Entre una serie de manuscritos del siglo XVIII atribuidos a Anselmo Arias Teixeiro hemos localizado el documento que presentamos en esta investigación, un conjunto heterogéneo de recetas destinadas a un público con escasos recursos económicos. Se trata de un tipo de obra relativamente frecuente a lo largo de aquel siglo, por lo cual, el autor se basa en algunas ediciones que circularon con relativo éxito, a pesar de sus evidentes limitaciones desde el punto de vista terapéutico. El manuscrito, que presentamos íntegramente, contribuye a ver la terapéuticadel siglo XVIII desde una óptica diferente, alejada de los tratados de medicina o las farmacopeas oficiales que caracterizaban a la nueva ciencia ilustrada. [gl] Entre unha serie de manuscritos do século XVIII atribuidos a Anselmo Arias Teixeiro localizamos o documento que amosamos nesta investigación, un conxunto heteroxéneo de receitas destiñadas a un público con escasos recursos económicos. Trátase dun tipo de obra relativamente frecuente ao longo daquel século, polo cal, o autor baséase nalgunhas edicións que circularon con relativo éxito, a pesares das súas evidentes limitacións dende o punto de vista terapéutico. O manuscrito, o cal amosamos íntegramente, contribúe a ve-la terapéutica do século XVIII dende unha óptica diferente

  19. Micropropagation of Wild Service Tree (Sorbus torminalis [L.] Crantz): The Regulative Role of Different Aromatic Cytokinins During Organogenesis

    Czech Academy of Sciences Publication Activity Database

    Malá, J.; Máchová, P.; Cvrčková, H.; Karady, Michal; Novák, Ondřej; Mikulík, Jaromír; Hauserová, Eva; Greplová, Jarmila; Strnad, Miroslav; Doležal, Karel

    2009-01-01

    Roč. 28, č. 4 (2009), s. 341-348 ISSN 0721-7595 R&D Projects: GA ČR GA206/07/0570; GA MŠk 1M06030 Institutional research plan: CEZ:AV0Z50380511 Keywords : Wild service tree * Micropropagation * Rooting Subject RIV: EF - Botanics Impact factor: 2.438, year: 2009

  20. Advanced reliability improvement of AC-modules (ARIA)

    International Nuclear Information System (INIS)

    Rooij, P.; Real, M.; Moschella, U.; Sample, T.; Kardolus, M.

    2001-09-01

    are fully or partially shaded. Alpha Real has conducted considerable testing of shading and temperature rises of up to 180C have been observed. Such a temperature rise will influence the lifetime and reliability of the module, and it is therefore common practice to protect modules from these conditions by using by-pass diodes. Having now an active element on the back of the module, such as a module integrated inverter, new possibilities are offered for new concepts for hot-spot prevention. The main conclusions of the ARIA project are: Both the AC module inverters, Sunmaster 130S and Edisun E230721G, withstood the electrical immunity tests successfully; The Sunmaster 130S passed the accelerated reliability tests with good results; The Edisun E230721G passed the temperature cycling test and a humidity-freezing test; The ANIT s.r.l. ARIA modules met all requirements of the CEI/IEC 61215 standard; The voltage comparison method is a most promising principle for hot spot detection. It is implemented into both the Solcolino E230721G and the Sunmaster 130S. The costs for a 200W module are about $1. to $2.5, where the costs for by-pass diodes are $4 to $15; Measurements at different locations in three countries have shown that the new Hot Spot Detector (HSD) by comparing the voltages operates. Computer simulations show that if the current through the shaded cell is less than or equal to the current generated by the shaded cell, the shaded cell will not become reverse biased. 10 refs

  1. Il telerilevamento per la qualità dell'aria L'esperienza SENSORER

    Directory of Open Access Journals (Sweden)

    Marco Folegani

    2012-04-01

    Full Text Available Il monitoraggio della qualità dell'aria con tecniche di telerilevamento è noto da tempo negli ambienti scientifici ma considerato ancora con prudenza e perplessità dalle strutture istituzionali sia per il livello "accademico" delle applicazioni sia per la mancanza di una forte motivazione normativa nell'adottare nuovi metodi di monitoraggio. L'esperienza SENSORER ha l'ambizione di mostrare come si possono superare entrambe queste barriere. The remote sensing for air quality monitoring The SENSORER project.The satellite observations have proven their capabilities for re-mote sensing of atmospheric pollutants such as the Particulate Matter. But the advantage of global coverage, homogeneous quality and a relative good spatial resolution are counterbalanced by the limited temporal resolution and the cloud cover-age. The SENSORER project is just the last example of a web platform that thanks to a combination of satellite data with information from ground based sensors and models overcomes the limitations of each single observation method to provide better pollution maps to make better decisions.

  2. Element interactions and soil properties affecting the soil-to-plant transfer of six elements relevant to radioactive waste in boreal forest

    International Nuclear Information System (INIS)

    Roivainen, Paeivi; Makkonen, Sari; Holopainen, Toini; Juutilainen, Jukka

    2012-01-01

    Cobalt (Co), lead (Pb), molybdenum (Mo), nickel (Ni), uranium (U), and zinc (Zn) are among the elements that have radioactive isotopes in radioactive waste. Soil-to-plant transfer is a key process for possible adverse effects if these radionuclides are accidentally released into the environment. The present study aimed at investigating factors affecting such transfer in boreal forest. The plant species studied were blueberry (Vaccinium myrtillus), May lily (Maianthemum bifolium), narrow buckler fern (Dryopteris carthusiana), rowan (Sorbus aucuparia) and Norway spruce (Picea abies). Regression analyses were carried out to investigate the effects of the chemical composition and physical properties of soil on the soil-to-leaf/needle concentration ratios of Co, Mo, Ni, Pb, U and Zn. Soil potassium (K), magnesium (Mg), manganese (Mn), phosphorus (P) and sulphur (S) concentrations were the most important factors affecting the soil-to-plant transfer of the elements studied. Soil clay and organic matter contents were found to significantly affect plant uptake of Mo, Pb and U. Knowledge of the effects of these factors is helpful for interpretation of the predictions of radioecological models describing soil-to-plant transfer and for improving such models. (orig.)

  3. Element interactions and soil properties affecting the soil-to-plant transfer of six elements relevant to radioactive waste in boreal forest

    Energy Technology Data Exchange (ETDEWEB)

    Roivainen, Paeivi; Makkonen, Sari; Holopainen, Toini; Juutilainen, Jukka [University of Eastern Finland, Department of Environmental Science, Kuopio (Finland)

    2012-03-15

    Cobalt (Co), lead (Pb), molybdenum (Mo), nickel (Ni), uranium (U), and zinc (Zn) are among the elements that have radioactive isotopes in radioactive waste. Soil-to-plant transfer is a key process for possible adverse effects if these radionuclides are accidentally released into the environment. The present study aimed at investigating factors affecting such transfer in boreal forest. The plant species studied were blueberry (Vaccinium myrtillus), May lily (Maianthemum bifolium), narrow buckler fern (Dryopteris carthusiana), rowan (Sorbus aucuparia) and Norway spruce (Picea abies). Regression analyses were carried out to investigate the effects of the chemical composition and physical properties of soil on the soil-to-leaf/needle concentration ratios of Co, Mo, Ni, Pb, U and Zn. Soil potassium (K), magnesium (Mg), manganese (Mn), phosphorus (P) and sulphur (S) concentrations were the most important factors affecting the soil-to-plant transfer of the elements studied. Soil clay and organic matter contents were found to significantly affect plant uptake of Mo, Pb and U. Knowledge of the effects of these factors is helpful for interpretation of the predictions of radioecological models describing soil-to-plant transfer and for improving such models. (orig.)

  4. Avoidance of nonhost plants by a bark beetle, Pityogenes bidentatus, in a forest of odors

    Science.gov (United States)

    Byers, John A.; Zhang, Qing-He; Birgersson, Göran

    The bark beetle, Pityogenes bidentatus (Coleoptera: Scolytidae), searches in mixed conifer and deciduous forests of northern Europe for suitable branches of its host, Scots pine (Pinus sylvestris). We tested whether odors from several diverse nonhost trees and plants common in the habitat (e.g., mountain ash, Sorbus aucuparia; oak, Quercus robur; alder buckthorn, Frangula alnus; blueberry, Vaccinium myrtillus; raspberry, Rubus idaeus; and grass, Deschampsia flexuosa) would reduce the attraction of the bark beetle to traps releasing its aggregation pheromone components in the field. Volatiles from the leaves or bark of each of these plants significantly reduced the attraction of the beetles to their pheromone. Odors collected from these nonhosts and analyzed by GC/MS contained monoterpenes, sesquiterpenes, and ``green-leaf'' alcohols, several of which (e.g., 1-octene-3-ol and β-caryophyllene) reduced the attraction to pheromone in the field and elicited electroantennographic responses. In the laboratory, reproduction by the beetle was marginal in nonhost Norway spruce, Picea abies, and was absent in the other nonhost trees. Olfactory avoidance of unsuitable nonhosts may have evolved due to advantages in avoiding mistakes during host selection.

  5. Control of plant defense mechanisms and fire blight pathogenesis through the regulation of 6-thioguanine biosynthesis in Erwinia amylovora.

    Science.gov (United States)

    Coyne, Sébastien; Litomska, Agnieszka; Chizzali, Cornelia; Khalil, Mohammed N A; Richter, Klaus; Beerhues, Ludger; Hertweck, Christian

    2014-02-10

    Fire blight is a devastating disease of Rosaceae plants, such as apple and pear trees. It is characterized by necrosis of plant tissue, caused by the phytopathogenic bacterium Erwinia amylovora. The plant pathogen produces the well-known antimetabolite 6-thioguanine (6TG), which plays a key role in fire blight pathogenesis. Here we report that YcfR, a member of the LTTR family, is a major regulator of 6TG biosynthesis in E. amylovora. Inactivation of the regulator gene (ycfR) led to dramatically decreased 6TG production. Infection assays with apple plants (Malus domestica cultivar Holsteiner Cox) and cell cultures of Sorbus aucuparia (mountain ash, rowan) revealed abortive fire blight pathogenesis and reduced plant response (biphenyl and dibenzofuran phytoalexin production). In the presence of the ΔycfR mutant, apple trees were capable of activating the abscission machinery to remove infected tissue. In addition to unveiling the regulation of 6TG biosynthesis in a major plant pathogen, we demonstrate for the first time that this antimetabolite plays a pivotal role in dysregulating the plant response to infection. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. New, rare or remarkable microfungi in the Italian Alps (Carnic Alps)--part I--ascomycotina.

    Science.gov (United States)

    Feige, G B; Ale-Agha, N; Jensen, M; Christiaans, B; Kricke, R

    2004-01-01

    During our observations in the SE part of the Carnic Alps in the year 2003 we were able to collect and identify 35 ascomycetes on trees and dead wood. Among these one can find numerous ascomycetes of different orders e.g. Pyrenomycetes, Loculoascomycetes and Discomycetes. Some species like Botryosphaeria ribis GROSENLUCHER & DUGGAR on Ribes alpinum L., Dothiora pyrenophora (FR.) FR. on Sorbus aucuparia L., Gemmamyces piceae (BORTH.) CASAGO. on Picea excelsa (LAM.) LINK, Glomerella montana (SACC.) v. ARX & E. MULLER on Sesleria caerulea (L.) ARD, Hymenoscyphus immutabilis (Fuck.) Dennis on Alnus incana (L.) Moench, Hysterographium fraxini (PERS. Ex. FR.) de Not. on Fraxinus ornus L., Lachnellula willkommii (Hartig) DENNIS [= Trichascyphella willkommii (Hartig) NANNF.] on Larix decidua MILL.,Leptosphaeria lycopodina (Mont.) SACC. on Lycopodium annotinum L., Mollisia adenostylidis REHM. on Adenostyles glabra (MILL.) DC., Pezicula cinnamomea (DC.)SACC. [ana: Cryptosporiopsis quercina PETRAK] on Quercus robur L., Pyrenopeziza petiolaris (A. & S. Ex FR.) NANNF. on Acer pseudoplatanus L., Tapesia rosae (PERS.) FUCKEL on Rosa canina L., are new for this area. All specimen are deposited in the Herbarium ESS Mycotheca Parva, Collection G.B. Feige/N. Ale-Agha.

  7. Lenguaje arcano y lenguaje del cuerpo: la hermenéutica bíblica de Arias Montano

    Directory of Open Access Journals (Sweden)

    Fernández Marcos, Natalio

    2002-06-01

    Full Text Available Arias Montano is known as the scientific supervisor of the Antwerp Polyglot Bible. But he was also one of the most important biblical intepreters in Renaissance Spain. From his exegetical commentaries, the prefaces to the Polyglot and particularly three treatises of the Apparatus, some of his hermeneutical principles can be gleaned. The author analyses these principles in the context of sixteenth century conception of Hebrew as the primordial and secret language. Special attention is paid to the idioms of biblical Hebrew and the force of the original sounds that can hardly be reproduced in other languages. Montano's insights into the language of the gestures and the body (treatise De Actione concerning the symbolic actions of the prophets, anticipate modern theories and strategies of communication.

    Arias Montano es conocido como el director científico de la Biblia Políglota de Amberes. Pero también fue uno de los intérpretes de la Biblia más importantes de la España renacentista. Es posible descubrir algunos de sus principios hermenéuticos en sus comentarios exegéticos, los prefacios de la Políglota y, especialmente, en sus tres tratados del Apparatus. El autor analiza dichos principios dentro del contexto del siglo XVI, que concebía el hebreo como la lengua primordial y secreta. De este modo, se hace especial hincapié en los modismos del hebreo bíblico, así como en la fuerza de los sonidos originales que difícilmente pueden reproducirse en otras lenguas. Las ideas de Montano sobre el lenguaje de los gestos y el lenguaje corporal (el tratado De Actione en relación con los actos simbólicos de los profetas se anticipan a las teorías modernas y a las estrategias de la comunicación.

  8. Floristic diversity in bashemsin valley of kackar mountains national park of rize, turkey

    International Nuclear Information System (INIS)

    Baykal, H.

    2016-01-01

    The floristical structure of Bashemsin and its environs as a protected and isolated area within Kackar Mountains National Park, situated in Rize, a province in the Blacksea region of Turkey, is studied. 1830 plant specimens were collected and 503 taxa were identified in 234 genera and 75 families. Sixteen Pteridophytes and 487 Spermatophytes were determined. Two of Spermatophytes are Gymnospermae while 485 of them are Angiospermae (98 Monocotyledones and 389 Dicotyledones). The richest families in taxa are Asteraceae, Poaceae, Brassicaceae, and Fabaceae (55 Asteraceae, 49 Poaceae, 28 Brassicaceae, and 27 Fabaceae). Phytogeographic elements are listed in order as: Euro-Siberian 247 (49.1%), Irano-Turanian 17 (3.4%), Mediterranean 6 (1.2%), multiregional-unknown phytogeographic root 233 (46.3%). Hemicryptophytes are the richest with 224 (44.5%) taxa and it is followed by cryptophytes 144 (28.6%), therophytes 53 (10.5%), chamaephytes 59 (11.7%), phanerophytes 19 (3.8%), vasicular parasites 2 (0.4%), nanophanerophytes/chamaephytes 1 (0.2%) and hydrophytes 1 (0.2%). 34 endemic taxa were determined (6.7%). 13 threatened taxa were detected in the research area and we determined that Sorbus caucasica Zinserl. var. yaltirikii Goksin population has fallen into CR endangered category with only 2 individuals in the study area. (author)

  9. Comparative genomics of 12 strains of Erwinia amylovora identifies a pan-genome with a large conserved core.

    Directory of Open Access Journals (Sweden)

    Rachel A Mann

    Full Text Available The plant pathogen Erwinia amylovora can be divided into two host-specific groupings; strains infecting a broad range of hosts within the Rosaceae subfamily Spiraeoideae (e.g., Malus, Pyrus, Crataegus, Sorbus and strains infecting Rubus (raspberries and blackberries. Comparative genomic analysis of 12 strains representing distinct populations (e.g., geographic, temporal, host origin of E. amylovora was used to describe the pan-genome of this major pathogen. The pan-genome contains 5751 coding sequences and is highly conserved relative to other phytopathogenic bacteria comprising on average 89% conserved, core genes. The chromosomes of Spiraeoideae-infecting strains were highly homogeneous, while greater genetic diversity was observed between Spiraeoideae- and Rubus-infecting strains (and among individual Rubus-infecting strains, the majority of which was attributed to variable genomic islands. Based on genomic distance scores and phylogenetic analysis, the Rubus-infecting strain ATCC BAA-2158 was genetically more closely related to the Spiraeoideae-infecting strains of E. amylovora than it was to the other Rubus-infecting strains. Analysis of the accessory genomes of Spiraeoideae- and Rubus-infecting strains has identified putative host-specific determinants including variation in the effector protein HopX1(Ea and a putative secondary metabolite pathway only present in Rubus-infecting strains.

  10. Stem CO2 efflux in six co-occurring tree species: underlying factors and ecological implications.

    Science.gov (United States)

    Rodríguez-Calcerrada, Jesús; López, Rosana; Salomón, Roberto; Gordaliza, Guillermo G; Valbuena-Carabaña, María; Oleksyn, Jacek; Gil, Luis

    2015-06-01

    Stem respiration plays a role in species coexistence and forest dynamics. Here we examined the intra- and inter-specific variability of stem CO2 efflux (E) in dominant and suppressed trees of six deciduous species in a mixed forest stand: Fagus sylvatica L., Quercus petraea [Matt.] Liebl, Quercus pyrenaica Willd., Prunus avium L., Sorbus aucuparia L. and Crataegus monogyna Jacq. We conducted measurements in late autumn. Within species, dominants had higher E per unit stem surface area (Es ) mainly because sapwood depth was higher than in suppressed trees. Across species, however, differences in Es corresponded with differences in the proportion of living parenchyma in sapwood and concentration of non-structural carbohydrates (NSC). Across species, Es was strongly and NSC marginally positively related with an index of drought tolerance, suggesting that slow growth of drought-tolerant trees is related to higher NSC concentration and Es . We conclude that, during the leafless period, E is indicative of maintenance respiration and is related with some ecological characteristics of the species, such as drought resistance; that sapwood depth is the main factor explaining variability in Es within species; and that the proportion of NSC in the sapwood is the main factor behind variability in Es among species. © 2014 John Wiley & Sons Ltd.

  11. Germán Rodríguez Arias y el cine central de Chillán (1945. Una historia del exilio catalán en Chile

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    David Caralt

    2011-08-01

    El presente artículo reivindica la figura de Rodríguez Arias y su aportación a la historia de la arquitectura chilena, explica su llegada a Chile y los motivos del encargo del Cine Central en base a una aproximación desde lo específico de la “arquitectura del exilio”. La parte final del texto se concentra en el discurrir del edificio y su estado actual de conservación.

  12. Hydrogen Apparent Fractionation between Precipitation and Leaf Wax n-Alkanes from Conifers and Deciduous Angiosperms along a Longitudinal Transect in Eurasia

    Science.gov (United States)

    Pedentchouk, Nikolai; Fisher, Katherine; Wagner, Thomas

    2010-05-01

    D/H composition of individual organic compounds derived from leaf wax may provide a wealth of information regarding plant-water relations in studies of plant ecology and climate change. Extracting that information from the organic D/H signal requires a thorough understanding of hydrogen isotope fractionation between environmental water and organic compounds. The purpose of this project is to investigate the importance of plant types and local climatic conditions on hydrogen apparent fractionation in higher terrestrial plants. We determined D/H composition of n-alkanes derived from leaf wax extracted from several extant plants representing common evergreen and deciduous conifer (Pinus and Larix) and deciduous angiosperm (Betula, Salix, and Sorbus) genera along a longitudinal transect from the UK to central Siberia at 10 different locations. These data were used to calculate the apparent fractionation factor (epsilon) between source water, estimated using the Online Isotopes in Precipitation Calculator, and n-alkanes. Our initial results show the following. First, we found large differences in the epsilon values among different genera at each location, e.g. Betula -63‰ vs. Salix -115‰ in Norwich, UK, and Betula -86‰ vs. Salix -146‰ in Novosibirsk, Russia. Assuming the plants at individual locations utilized soil water of very similar deltaD values, variations in the epsilon values are likely to be explained by differences in plant physiology and biochemistry. Second, we identified extensive shifts in the epsilon values in individual species along the transect from the UK to central Siberia, e.g. Betula -63‰ in Norwich vs. -104‰ in Zotino, Krasnoyarsk Krai, central Siberia and Salix -115‰ in Norwich vs. -164‰ in Sodankyla, Finland. With the exception of Sorbus, there is a positive relationship between the MAT (mean annual temperature) and epsilon values at locations above 2 °C MAT, suggesting a possible climatic effect on isotopic fractionation

  13. Agroforestry management and phytoseiid communities in vineyards in the South of France.

    Science.gov (United States)

    Liguori, Marialivia; Tixier, Marie-Stéphane; Hernandes, Akashi Fabio; Douin, Martial; Kreiter, Serge

    2011-10-01

    This study deals with the long-term effect of agroforestry management (trees within vine crops) on communities of phytoseiid mites. Several plots were considered: vineyards co-planted with Sorbus domestica or Pinus pinea, monocultures of vines and monocultures of S. domestica or P. pinea. All vine plots included two vine cultivars, Syrah and Grenache. Phytoseiid mites have been surveyed in these plots during several years within the previous 10 years. In 2010, samplings were again carried out in these same plots, from May to September, twice a month. Significantly higher densities of Phytoseiidae were observed on the cultivar Syrah (0.85 phytoseiids per leaf) than on Grenache (0.26 phytoseiids per leaf). Furthermore, significantly higher phytoseiid mite densities were observed in the monocultural grapevine plot than in the two co-planted ones. The main species found was Typhlodromus (Typhlodromus) exhilaratus in all vine plots considered. However, Kampimodromus aberrans was observed in the grapevine plots co-planted with the two trees, but never in the monocultural vine plot. Surprisingly, this phytoseiid species was not found on the co-planted trees, nor in the neighbouring uncultivated vegetation. Several hypotheses are discussed to explain such an unexpected distribution. Furthermore, contrary to what has been observed previously, agroforestry management did not seem to favour phytoseiid mite development, especially on the Grenache cultivar. Again, some hypotheses are developed to explain such observations and density modifications.

  14. Estonian folk traditional experiences on natural anticancer remedies: from past to the future.

    Science.gov (United States)

    Sak, Katrin; Jürisoo, Kadi; Raal, Ain

    2014-07-01

    Despite diagnostic and therapeutic advancements, the burden of cancer is still increasing worldwide. Toxicity of current chemotherapeutics to normal cells and their resistance to tumor cells highlights the urgent need for new drugs with minimal adverse side effects. The use of natural anticancer agents has entered into the area of cancer research and increased efforts are being made to isolate bioactive products from medicinal plants. To lead the search for plants with potential cytotoxic activity, ethnopharmacological knowledge can give a great contribution. Therefore, the attention of this review is devoted to the natural remedies traditionally used for the cancer treatment by Estonian people over a period of almost 150 years. Two massive databases, the first one stored in the Estonian Folklore Archives and the second one in the electronic database HERBA ( http://herba.folklore.ee/ ), containing altogether more than 30 000 ethnomedicinal texts were systematically reviewed to compile data about the Estonian folk traditional experiences on natural anticancer remedies. As a result, 44 different plants with potential anticancer properties were elicited, 5 of which [Angelica sylvestris L. (Apiaceae), Anthemis tinctoria L. (Asteraceae), Pinus sylvestris L. (Pinaceae), Sorbus aucuparia L. (Rosaceae), and Prunus padus L. (Rosaceae)] have not been previously described with respect to their tumoricidal activities in the scientific literature, suggesting thus the potential herbal materials for further investigations of natural anticancer compounds.

  15. Flowers of Çoruh Valley

    Directory of Open Access Journals (Sweden)

    Ramazan Çakmakçı

    2018-01-01

    Full Text Available Coruh valley has an important biological diversity in term of plants, flora-fauna, wildlife and ecosystems. These regions contain the landraces, wild and weedy relatives, other wild, herbaceous and flowering trees, herbaceous flowering plants, medicinal and aromatic and flowering and ornamental shrubs plants species which are especially economically important plant for floriculture, eco-tourism, botanical tourism and nature tourism. Many important medicinal and aromatic and ornamental plants species are found in this region and naturally grow. It is considered that Acantholimon, Achillea, Alkanna, Allium, Amygdalus, Angelica, Anemone, Anthemis, Arabis, Arctium, Artemisia, Asparagus, Asperula, Astragalus, Calamintha, Calendula, Calutea, Campanula, Capparis, Cardamine, Centaurea, Cephalanthera, Cephalaria, Chelidonium, Chenopodium, Chysanthemum, Colchicum, Consolida, Coriandrum, Cornus, Coronilla, Cerasus, Cotoneaster, Crataegus, Crocus, Cyclamen, Dactylorhiza, Digitalis, Dianthus, Draba, Echinops, Equisetum, Ferula, Filipendula, Fritillaria, Fumaria, Gagea, Galanthus, Galium, Genista, Gentiana, Geranium, Geum, Gladiolus, Glychirrza, Helichrysum, Hesperis, Hypericum, İnula, İris, Isatis, Juniperus, Lilium, Linaria, Linum, lysimachia, Malus, Malva, Marrubium, Melissa, Mentha, Micromeria, Morina, Muscari, Mysotis, Narcissus, Neotchichatchewia, Nepeta, Onobrychis, Orchis, Ornithogalum, Origanum, Paeonia, Papaver, Pedicularis, Peganum, Phelypaea, Platanthera, Plantago, Pilosella, Pelargonium, Potentilla, Polygonum, Polygala, Primula, Punica, Prunus, Pyrus, Ranunculus, Rhamnus, Rhododendron, Rhus, Rosa, Rubia, Rubus, Rumex, Salvia, Sambucus, Satureja, Scilla, Scorzonera, Scutellaria, Sedum, Sempervivum, Sideritis, Sophora, Sorbus, Stachys, Tanecetum, Teucrium, Thymus, Trigonella, Tulipa, Tussilago, Uechtriitzia, Vaccinium, Verbascum, Verbena, Veronica, Viburnum and Ziziphora species commonly found in the region may be may be evaluated economically.

  16. Phytoalexins of the Pyrinae: Biphenyls and dibenzofurans

    Directory of Open Access Journals (Sweden)

    Cornelia Chizzali

    2012-04-01

    Full Text Available Biphenyls and dibenzofurans are the phytoalexins of the Pyrinae, a subtribe of the plant family Rosaceae. The Pyrinae correspond to the long-recognized Maloideae. Economically valuable species of the Pyrinae are apples and pears. Biphenyls and dibenzofurans are formed de novo in response to infection by bacterial and fungal pathogens. The inducible defense compounds were also produced in cell suspension cultures after treatment with biotic and abiotic elicitors. The antimicrobial activity of the phytoalexins was demonstrated. To date, 10 biphenyls and 17 dibenzofurans were isolated from 14 of the 30 Pyrinae genera. The most widely distributed compounds are the biphenyl aucuparin and the dibenzofuran γ-cotonefuran. The biosynthesis of the two classes of defense compounds is not well understood, despite the importance of the fruit crops. More recent studies have revealed simultaneous accumulation of biphenyls and dibenzofurans, suggesting sequential, rather than the previously proposed parallel, biosynthetic pathways. Elicitor-treated cell cultures of Sorbus aucuparia served as a model system for studying phytoalexin metabolism. The key enzyme that forms the carbon skeleton is biphenyl synthase. The starter substrate for this type-III polyketide synthase is benzoyl-CoA. In apples, biphenyl synthase is encoded by a gene family, members of which are differentially regulated. Metabolism of the phytoalexins may provide new tools for designing disease control strategies for fruit trees of the Pyrinae subtribe.

  17. Potential and limitation of combining terrestrial and marine growth records from Iceland

    Science.gov (United States)

    Piermattei, A.; Urbinati, C.; Tonelli, E.; Eggertsson, Ó.; Levanič, T.; Kaczka, R. J.; Andrew, C.; Schöne, B. R.; Büntgen, U.

    2017-08-01

    Seasonally formed, perennial growth increments of various organisms may possibly contain information about past environmental changes, well before instrumental measurements occurred. Such annually resolved proxy records have been mainly obtained from terrestrial archives, with a paucity of similar data originating from marine habitats. Iceland represents ideal conditions to develop both, tree ring (dendro) and bivalve shell (sclero) chronologies from adjacent sites. Here we introduce the first network of Icelandic birch (Betula pubescens Ehrh.) and rowan (Sorbus aucuparia) dendrochronologies, as well as ocean quahog (Arctica islandica L.) sclerochronologies. In order to identify the dominant external drivers of tree and shell growth, we assess the common growth trends and growth extremes within and between the terrestrial and marine records, as well as relationships of both archives with instrumental-based meteorological indices. Capturing a strong signal of June-August mean air temperature, the dendrochronologies are significantly positively correlated to each other. The sclerochronologies, however, reveal much lower growth coherency, which likely results from different sampling strategies and growth habitats. Disagreement between the dendro- and sclerochronologies possibly originates from unequal sample size, offset in the seasonal timing and rate of the growth, as well as varying sensitivities to different environmental factors. Our results emphasize the importance of considering a wide range of species and taxa to reconstruct a more complete picture of terrestrial and marine ecosystem functioning and productivity across various spatiotemporal scales.

  18. Influence of changes in crop cultivation areas on pollen contents of honey (Research Note

    Directory of Open Access Journals (Sweden)

    A.-L. VARIS

    2008-12-01

    Full Text Available Pollen counts were done on honey collected by a Finnish honey corporation in late summer 1997 from the entire beekeeping area of Finland. The most common pollen type was Brassicaceae pollen, which was represented by 60% of the grains counted. It was followed by Salix spp. (10%, Trifolium repens + T. hybridum (10% and T. pratense + T. medium (6.5% species. Pollen grains of Phacelia spp, Filipendula ulmaria, Apiaceae, Sorbus aucuparia, Malus domestica, and Rubus idaeus were also numerous. These pollen types constituted 96% of all the pollen examined. These results and those of the earlier pollen counts in Finland were compared with the cultivation areas of the most important nectariferous crops. In the 1930s white clover was the most important honey source in Finland and its pollen was very dominant in honey. Since the 1950s oilseed crops have been grown in increasing rates and pure timothy-meadow fescue pastures and hay stands with heavy N applications have decreased the share of Trifolium species. The proportion of Brassicaceae pollen has continuously increased with the increase of the growing area of turnip rape Brassica rapa ssp. oleifera and rape, B. napus ssp. oleifera. At the same time the proportion of T. repens + T. hybridum pollen has decreased so that their mutual relationships are now reversed compared to the beginning of the 1960s. Changes in land use were thus very clearly to be seen in the pollen content of honey.;

  19. Possibilities of cultivating ornamental trees and shrubs under conditions of air pollution with oxides of sulfur

    Energy Technology Data Exchange (ETDEWEB)

    Bialobok, S.; Bartkowiak, S.; Rachwal, L.

    1974-01-01

    The field work conducted has shown that high concentrations of SO/sub 2/ in the air can be withstood by the following trees and shrubs. Trees: Acer campestris, A. platanoides, Ailanthus altissima, Aesculus hippocastanum, Morus alba, Platanus acerifolia, Pinus strobur, P. nigra, Populus Berolinensis, P. candicans, P. Hybr. 27, P. Marilandica, P. simonii, P. Serotina, Quercus robus, Robinia pseudoacacia. Shrubs: Caragana arborescens, Crataegus oxyacantha, C. monogyna, Cerasus mehaleb, Forsythia/most of the species and varieties/, Ligustrum vulgare, Philadelphus coronaria, Ptelea trifoliata, Sambucus nigra, Salix caprea, Sorbaria sorbifolia, Sorbus aucuparia, Taxus baccata. For the selection of trees and shrubs in the laboratory, high concentrations of SO/sub 2/ were used (60-150 ppm for a period of 10 minutes). Experiments were conducted on cut shrubs kept in the gas chambers. In order to estimate the degree of their injury, they were transferred to a shaded greenhouse. A concentration of 65 ppm of SO/sub 2/ could be withstood by the following Forsythias: Forsythia intermedia Primulina, F. Densiflora, F. Spectabilis, F. giraldina, F. suspensa, F. koreana, F. ovata, F. japonica and Hippophae rhamnoides. A concentration of 130 ppm could be withstood only by F. intermedia Vitelina. A similarly high concentration of SO/sub 2/ could be withstood by shoots and leaves of Ailanthus girladii Duclouxii and by Platanus acerifolia. From among the lilacs Syringa pekinensis and S. amurensis proved resistant to high concentrations of SO/sub 2/.

  20. A Inquisição e a Feitiçaria: A Ritualização do Interrogatório e da Tortura * The Inquisition and Witchcraft: the Ritualization of Inquiries and Torture

    Directory of Open Access Journals (Sweden)

    JOÃO DAVI AVELAR PIRES

    2014-02-01

    Full Text Available Resumo: Este trabalho se propõe a pensar a Inquisição, principalmente a medieval, como uma extensão ou organização católica que buscava a erradicação daqueles que se opunham aos dogmas e a moral pregadas pela Igreja. Fundamentados pelo conceito de ritual, apresentamos a relação entre a Inquisição e as mulheres acusadas de feitiçaria como um ritual, que se inicia desde o momento da captura das acusadas, passando pelos interrogatórios, pela tortura e chegando até o auto-de-fé, onde era queimada num local público, geralmente em feriados ou dias santos.Palavras-chave: Inquisição – Feitiçaria – Ritual. Abstract: his paper proposes to think the Inquisition, mainly medieval, as an extension or Catholic organization that sought to eradicate those who opposed the beliefs and morality preached by the Church. Basing on the concept of ritual, we present the relationship between the Inquisition and women accused of witchcraft as a ritual, which begins from the moment of capture of the accused, throughout the  inquiry and torture until  reaching the act of faith, where she  was burnt  at a public place, usually on holidays.Keywords: Inquisition – Witchcraft – Ritual.

  1. The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients: An interobserver study.

    Science.gov (United States)

    Martens, Roland M; Bechten, Arianne; Ingala, Silvia; van Schijndel, Ronald A; Machado, Vania B; de Jong, Marcus C; Sanchez, Esther; Purcell, Derk; Arrighi, Michael H; Brashear, Robert H; Wattjes, Mike P; Barkhof, Frederik

    2018-03-01

    Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer's disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is crucial to evaluate subjects enrolled in clinical trials. To investigate the applicability of subtraction MRI in the ARIA-E detection using an established ARIA-E-rating scale. We included 75 AD patients receiving bapineuzumab treatment, including 29 ARIA-E cases. Five neuroradiologists rated their brain MRI-scans with and without subtraction images. The accuracy of evaluating the presence of ARIA-E, intraclass correlation coefficient (ICC) and specific agreement was calculated. Subtraction resulted in higher sensitivity (0.966) and lower specificity (0.970) than native images (0.959, 0.991, respectively). Individual rater detection was excellent. ICC scores ranged from excellent to good, except for gyral swelling (moderate). Excellent negative and good positive specific agreement among all ARIA-E imaging features was reported in both groups. Combining sulcal hyperintensity and gyral swelling significantly increased positive agreement for subtraction images. Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. However, in order to improve its usefulness isotropic acquisition and enhanced training are required. The ARIA-E rating scale may benefit from combining sulcal hyperintensity and swelling. • Subtraction technique can improve detection amyloid-related imaging-abnormalities with edema/effusion in Alzheimer's patients. • The value of ARIA-E detection, classification and monitoring using subtraction was assessed. • Validation of an established ARIA-E rating scale, recommendations for improvement are reported. • Complementary statistical methods were employed to measure accuracy, inter-rater-reliability and specific agreement.

  2. The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients. An interobserver study

    International Nuclear Information System (INIS)

    Martens, Roland M.; Bechten, Arianne; Ingala, Silvia; Schijndel, Ronald A. van; Machado, Vania B.; Jong, Marcus C. de; Sanchez, Esther; Wattjes, Mike P.; Purcell, Derk; Arrighi, Michael H.; Brashear, Robert H.; Barkhof, Frederik

    2018-01-01

    Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer's disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is crucial to evaluate subjects enrolled in clinical trials. To investigate the applicability of subtraction MRI in the ARIA-E detection using an established ARIA-E-rating scale. We included 75 AD patients receiving bapineuzumab treatment, including 29 ARIA-E cases. Five neuroradiologists rated their brain MRI-scans with and without subtraction images. The accuracy of evaluating the presence of ARIA-E, intraclass correlation coefficient (ICC) and specific agreement was calculated. Subtraction resulted in higher sensitivity (0.966) and lower specificity (0.970) than native images (0.959, 0.991, respectively). Individual rater detection was excellent. ICC scores ranged from excellent to good, except for gyral swelling (moderate). Excellent negative and good positive specific agreement among all ARIA-E imaging features was reported in both groups. Combining sulcal hyperintensity and gyral swelling significantly increased positive agreement for subtraction images. Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. However, in order to improve its usefulness isotropic acquisition and enhanced training are required. The ARIA-E rating scale may benefit from combining sulcal hyperintensity and swelling. (orig.)

  3. The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients. An interobserver study

    Energy Technology Data Exchange (ETDEWEB)

    Martens, Roland M.; Bechten, Arianne; Ingala, Silvia; Schijndel, Ronald A. van; Machado, Vania B.; Jong, Marcus C. de; Sanchez, Esther; Wattjes, Mike P. [VU University Medical Center, Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Netherlands); Purcell, Derk [California Pacific Medical Center, Department of Radiology, San Francisco, CA (United States); BioClinica Inc, Newark, CA (United States); Arrighi, Michael H.; Brashear, Robert H. [Janssen Alzheimer Immunotherapy Research and Development, LLC, South San Francisco, CA (United States); Barkhof, Frederik [VU University Medical Center, Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Netherlands); University College London, Institutes of Neurology and Healthcare Engineering, London (United Kingdom)

    2018-03-15

    Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer's disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is crucial to evaluate subjects enrolled in clinical trials. To investigate the applicability of subtraction MRI in the ARIA-E detection using an established ARIA-E-rating scale. We included 75 AD patients receiving bapineuzumab treatment, including 29 ARIA-E cases. Five neuroradiologists rated their brain MRI-scans with and without subtraction images. The accuracy of evaluating the presence of ARIA-E, intraclass correlation coefficient (ICC) and specific agreement was calculated. Subtraction resulted in higher sensitivity (0.966) and lower specificity (0.970) than native images (0.959, 0.991, respectively). Individual rater detection was excellent. ICC scores ranged from excellent to good, except for gyral swelling (moderate). Excellent negative and good positive specific agreement among all ARIA-E imaging features was reported in both groups. Combining sulcal hyperintensity and gyral swelling significantly increased positive agreement for subtraction images. Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. However, in order to improve its usefulness isotropic acquisition and enhanced training are required. The ARIA-E rating scale may benefit from combining sulcal hyperintensity and swelling. (orig.)

  4. Verdugo, M.A., Gómez, L.E., Arias, B., Santamaría, M., Clavero, D. y Tamarit, J. (2013. Escala INICO-FEAPS: Evaluación Integral de la Calidad de Vida de personas con Discapacidad Intelectual o del Desarrollo. Salamanca: INICO.

    Directory of Open Access Journals (Sweden)

    Pilar Porras Navalón

    2014-06-01

    Full Text Available Reseña de la obra 'Escala INICO-FEAPS: Evaluación Integral de la Calidad de Vida de personas con Discapacidad Intelectual o del Desarrollo' (2013 de Miguel Ángel Verdugo Alonso, Laura Elísabet Gómez Sánchez, Benito Arias Martínez, Mónica Santamaría Domínguez, Daniel Clavero Herrero y Javier Tamarit Cuadrado.

  5. How training citizen scientists affects the accuracy and precision of phenological data

    Science.gov (United States)

    Feldman, Richard E.; Žemaitė, Irma; Miller-Rushing, Abraham J.

    2018-05-01

    Monitoring plant and animal phenology is a critical step to anticipating and predicting changes in species interactions and biodiversity. Because phenology necessarily involves frequent and repeated observations over time, citizen scientists have become a vital part of collecting phenological data. However, there is still concern over the accuracy and precision of citizen science data. It is possible that training citizen scientists can improve data quality though there are few comparisons of trained and untrained citizen scientists in the ability of each to accurately and precisely measure phenology. We assessed how three types of observers—experts, trained citizen scientists that make repeated observations, and untrained citizen scientists making once-per-year observations—differ in quantifying temporal change in flower and fruit abundance of American mountain ash trees (Sorbus americana Marsh.) and arthropods in Acadia National Park, Maine, USA. We found that trained more so than untrained citizen science observers over- or under-estimated abundances leading to precise but inaccurate characterizations of phenological patterns. Our results suggest a new type of bias induced by repeated observations: A type of learning takes place that reduces the independence of observations taken on different trees or different dates. Thus, in this and many other cases, having individuals make one-off observations of marked plants may produce data as good if not better than individuals making repeated observations. For citizen science programs related to phenology, our results underscore the importance of (a) attracting the most number of observers possible even if they only make one observation, (b) producing easy-to-use and informative data sheets, and (c) carefully planning effective training programs that are, perhaps, repeated at different points during the data collection period.

  6. Crowdsourcing and Automated Retinal Image Analysis for Diabetic Retinopathy.

    Science.gov (United States)

    Mudie, Lucy I; Wang, Xueyang; Friedman, David S; Brady, Christopher J

    2017-09-23

    As the number of people with diabetic retinopathy (DR) in the USA is expected to increase threefold by 2050, the need to reduce health care costs associated with screening for this treatable disease is ever present. Crowdsourcing and automated retinal image analysis (ARIA) are two areas where new technology has been applied to reduce costs in screening for DR. This paper reviews the current literature surrounding these new technologies. Crowdsourcing has high sensitivity for normal vs abnormal images; however, when multiple categories for severity of DR are added, specificity is reduced. ARIAs have higher sensitivity and specificity, and some commercial ARIA programs are already in use. Deep learning enhanced ARIAs appear to offer even more improvement in ARIA grading accuracy. The utilization of crowdsourcing and ARIAs may be a key to reducing the time and cost burden of processing images from DR screening.

  7. Berry fruits: compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease.

    Science.gov (United States)

    Seeram, Navindra P

    2008-02-13

    An overwhelming body of research has now firmly established that the dietary intake of berry fruits has a positive and profound impact on human health, performance, and disease. Berry fruits, which are commercially cultivated and commonly consumed in fresh and processed forms in North America, include blackberry ( Rubus spp.), black raspberry ( Rubus occidentalis), blueberry ( Vaccinium corymbosum), cranberry (i.e., the American cranberry, Vaccinium macrocarpon, distinct from the European cranberry, V. oxycoccus), red raspberry ( Rubus idaeus) and strawberry ( Fragaria x ananassa). Other berry fruits, which are lesser known but consumed in the traditional diets of North American tribal communities, include chokecherry ( Prunus virginiana), highbush cranberry ( Viburnum trilobum), serviceberry ( Amelanchier alnifolia), and silver buffaloberry ( Shepherdia argentea). In addition, berry fruits such as arctic bramble ( Rubus articus), bilberries ( Vaccinuim myrtillus; also known as bog whortleberries), black currant ( Ribes nigrum), boysenberries ( Rubus spp.), cloudberries ( Rubus chamaemorus), crowberries ( Empetrum nigrum, E. hermaphroditum), elderberries ( Sambucus spp.), gooseberry ( Ribes uva-crispa), lingonberries ( Vaccinium vitis-idaea), loganberry ( Rubus loganobaccus), marionberries ( Rubus spp.), Rowan berries ( Sorbus spp.), and sea buckthorn ( Hippophae rhamnoides), are also popularly consumed in other parts of the world. Recently, there has also been a surge in the consumption of exotic "berry-type" fruits such as the pomegranate ( Punica granatum), goji berries ( Lycium barbarum; also known as wolfberry), mangosteen ( Garcinia mangostana), the Brazilian açaí berry ( Euterpe oleraceae), and the Chilean maqui berry ( Aristotelia chilensis). Given the wide consumption of berry fruits and their potential impact on human health and disease, conferences and symposia that target the latest scientific research (and, of equal importance, the dissemination of

  8. The abundance and pollen foraging behaviour of bumble bees in relation to population size of whortleberry (Vaccinium uliginosum.

    Directory of Open Access Journals (Sweden)

    Carolin Mayer

    Full Text Available Habitat fragmentation can have severe effects on plant pollinator interactions, for example changing the foraging behaviour of pollinators. To date, the impact of plant population size on pollen collection by pollinators has not yet been investigated. From 2008 to 2010, we monitored nine bumble bee species (Bombus campestris, Bombus hortorum s.l., Bombus hypnorum, Bombus lapidarius, Bombus pascuorum, Bombus pratorum, Bombus soroensis, Bombus terrestris s.l., Bombus vestalis s.l. on Vaccinium uliginosum (Ericaceae in up to nine populations in Belgium ranging in size from 80 m(2 to over 3.1 ha. Bumble bee abundance declined with decreasing plant population size, and especially the proportion of individuals of large bumble bee species diminished in smaller populations. The most remarkable and novel observation was that bumble bees seemed to switch foraging behaviour according to population size: while they collected both pollen and nectar in large populations, they largely neglected pollen collection in small populations. This pattern was due to large bumble bee species, which seem thus to be more likely to suffer from pollen shortages in smaller habitat fragments. Comparing pollen loads of bumble bees we found that fidelity to V. uliginosum pollen did not depend on plant population size but rather on the extent shrub cover and/or openness of the site. Bumble bees collected pollen only from three plant species (V.uliginosum, Sorbus aucuparia and Cytisus scoparius. We also did not discover any pollination limitation of V. uliginosum in small populations. We conclude that habitat fragmentation might not immediately threaten the pollination of V. uliginosum, nevertheless, it provides important nectar and pollen resources for bumble bees and declining populations of this plant could have negative effects for its pollinators. The finding that large bumble bee species abandon pollen collection when plant populations become small is of interest when

  9. Early establishment of trees at the alpine treeline: idiosyncratic species responses to temperature-moisture interactions.

    Science.gov (United States)

    Loranger, Hannah; Zotz, Gerhard; Bader, Maaike Y

    2016-01-01

    On a global scale, temperature is the main determinant of arctic and alpine treeline position. However on a local scale, treeline form and position vary considerably due to other climatic factors, tree species ecology and life-stage-dependent responses. For treelines to advance poleward or uphill, the first steps are germination and seedling establishment. These earliest life stages may be major bottlenecks for treeline tree populations and will depend differently on climatic conditions than adult trees. We investigated the effect of soil temperature and moisture on germination and early seedling survival in a field experiment in the French Alps near the local treeline (2100 m a.s.l.) using passive temperature manipulations and two watering regimes. Five European treeline tree species were studied: Larix decidua, Picea abies, Pinus cembra, Pinus uncinata and Sorbus aucuparia In addition, we monitored the germination response of three of these species to low temperatures under controlled conditions in growth chambers. The early establishment of these trees at the alpine treeline was limited either by temperature or by moisture, the sensitivity to one factor often depending on the intensity of the other. The results showed that the relative importance of the two factors and the direction of the effects are highly species-specific, while both factors tend to have consistent effects on both germination and early seedling survival within each species. We show that temperature and water availability are both important contributors to establishment patterns of treeline trees and hence to species-specific forms and positions of alpine treelines. The observed idiosyncratic species responses highlight the need for studies including several species and life-stages to create predictive power concerning future treeline dynamics. © The Authors 2016. Published by Oxford University Press on behalf of the Annals of Botany Company.

  10. Responses of Tree Seedlings near the Alpine Treeline to Delayed Snowmelt and Reduced Sky Exposure

    Directory of Open Access Journals (Sweden)

    Maaike Y. Bader

    2017-12-01

    Full Text Available Earlier snowmelt changes spring stress exposure and growing-season length, possibly causing shifts in plant species dominance. If such shifts involve trees, this may lead to changes in treeline position. We hypothesized that earlier snowmelt would negatively affect the performance of tree seedlings near the treeline due to higher spring stress levels, but less so if seedlings were protected from the main stress factors of night frosts and excess solar radiation. We exposed seedlings of five European treeline tree species: Larix decidua, Picea abies, Pinus cembra, Pinus uncinata, and Sorbus aucuparia to two snow-cover treatments (early and late melting, with about two weeks difference combined with reduced sky exposure during the day (shading or night (night warming, repeated in two years, at a site about 200 m below the regional treeline elevation. Physiological stress levels (as indicated by lower Fv/Fm in the first weeks after emergence from snow were higher in early-emerging seedlings. As expected, shade reduced stress, but contrary to expectation, night warming did not. However, early- and late-emerging seedlings did not differ overall in their growth or survival, and the interaction with shading was inconsistent between years. Overall, shading had the strongest effect, decreasing stress levels and mortality (in the early-emerging seedlings only, but also growth. A two-week difference in snow-cover duration did not strongly affect the seedlings, although even smaller differences have been shown to affect productivity in alpine and arctic tundra vegetation. Still, snowmelt timing cannot be discarded as important for regeneration in subalpine conditions, because (1 it is likely more critical in very snow-rich or snow-poor mountains or landscape positions; and (2 it can change (subalpine vegetation phenology and productivity, thereby affecting plant interactions, an aspect that should be considered in future studies.

  11. Ecosystems effects 25 years after Chernobyl: pollinators, fruit set and recruitment.

    Science.gov (United States)

    Møller, Anders Pape; Barnier, Florian; Mousseau, Timothy A

    2012-12-01

    Animals are assumed to play a key role in ecosystem functioning through their effects on seed set, seed consumption, seed dispersal, and maintenance of plant communities. However, there are no studies investigating the consequences of animal scarcity on seed set, seed consumption and seed dispersal at large geographical scales. We exploited the unprecedented scarcity of pollinating bumblebees and butterflies in the vicinity of Chernobyl, Ukraine, linked to the effects of radiation on pollinator abundance, to test for effects of pollinator abundance on the ecosystem. There were considerably fewer pollinating insects in areas with high levels of radiation. Fruit trees and bushes (apple Malus domestica, pear Pyrus communis, rowan Sorbus aucuparia, wild rose Rosa rugosa, twistingwood Viburnum lantana, and European cranberry bush Viburnum opulus) that are all pollinated by insects produced fewer fruit in highly radioactively contaminated areas, partly linked to the local reduction in abundance of pollinators. This was the case even when controlling for the fact that fruit trees were generally smaller in more contaminated areas. Fruit-eating birds like thrushes and warblers that are known seed dispersers were less numerous in areas with lower fruit abundance, even after controlling for the effects of radiation, providing a direct link between radiation, pollinator abundance, fruit abundance and abundance of frugivores. Given that the Chernobyl disaster happened 25 years ago, one would predict reduced local recruitment of fruit trees if fruit set has been persistently depressed during that period; indeed, local recruitment was negatively related to the level of radiation and positively to the local level of fruit set. The patterns at the level of trees were replicated at the level of villages across the study site. This study provides the first large-scale study of the effects of a suppressed pollinator community on ecosystem functioning.

  12. Evaluation of pollutant emissions in North China Plain using aircraft measurements from the Air Chemistry Research In Asia (ARIAs) campaign

    Science.gov (United States)

    He, H.; Ren, X.; Li, Z.; Dickerson, R. R.

    2017-12-01

    The North China Plain (NCP) is one of the most populated and polluted regions on Earth. With rapid economic development in past decades, air pollution including heavy atmospheric aerosol loadings became severe in this region, leading to environmental and climate problems. An aircraft campaign, Air Chemistry Research In Asia (ARIAs), was conducted in spring 2016 (in parallel to KORUS-AQ) to understand air quality in the NCP and transport of air pollutants from this area. Measurements of trace gases such as O3, CO, and SO2 and aerosol optical properties were analyzed to investigate the anthropogenic emissions in the NCP. Both high-efficiency combustion such as from automobiles and modern power plants as well as low-efficiency combustion such as from biomass burnings were identified. Transformations of primary pollutants and formation of secondary pollutants were simulated using the EPA CMAQ v5.2 model. The global HTAP-EDGAR v4.2 emission inventory of year 2010 was processed with SMOKE v4.5 to drive CMAQ. Modeling results were evaluated with aircraft observations to improve our knowledge of anthropogenic emissions and transport. We also used satellite observations including OMI SO2/NO2 and MODIS AOD to evaluate the model performance in the NCP. Through the comparison, we estimated the changes in emissions of major anthropogenic pollutants from 2010 to 2016. Sensitivity experiments with improved emission inventory were conducted to better investigate the air pollution in the NCP.

  13. SU-F-T-262: Commissioning Varian Portal Dosimetry for EPID-Based Patient Specific QA in a Non-Aria Environment

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, M; Knutson, N [Rhode Island Hospital, Providence RI (United States); University of Rhode Island, Kingston, RI (United States); University of Massachusetts Lowell, Lowell, MA (United States); Herrington, J [University of Rhode Island, Kingston, RI (United States); Price, M [Rhode Island Hospital, Providence RI (United States); University of Rhode Island, Kingston, RI (United States); Alpert Medical School of Brown University, Providence, RI (United States)

    2016-06-15

    Purpose: Development of an in-house program facilitates a workflow that allows Electronic Portal Imaging Device (EPID) patient specific quality assurance (QA) measurements to be acquired and analyzed in the Portal Dosimetry Application (Varian Medical Systems, Palo Alto, CA) using a non-Aria Record and Verify (R&V) system (MOSAIQ, Elekta, Crawley, UK) to deliver beams in standard clinical treatment mode. Methods: Initial calibration of an in-house software tool includes characterization of EPID dosimetry parameters by importing DICOM images of varying delivered MUs to determine linear mapping factors in order to convert image pixel values to Varian-defined Calibrated Units (CU). Using this information, the Portal Dose Image Prediction (PDIP) algorithm was commissioned by converting images of various field sizes to output factors using the Eclipse Scripting Application Programming Interface (ESAPI) and converting a delivered configuration fluence to absolute dose units. To verify the algorithm configuration, an integrated image was acquired, exported directly from the R&V client, automatically converted to a compatible, calibrated dosimetric image, and compared to a PDIP calculated image using Varian’s Portal Dosimetry Application. Results: For two C-Series and one TrueBeam Varian linear accelerators, gamma comparisons (global 3% / 3mm) of PDIP algorithm predicted dosimetric images and images converted via the inhouse system demonstrated agreement for ≥99% of all pixels, exceeding vendor-recommended commissioning guidelines. Conclusion: Combinations of a programmatic image conversion tool and ESAPI allow for an efficient and accurate method of patient IMRT QA incorporating a 3rd party R&V system.

  14. An MRI rating scale for amyloid-related imaging abnormalities with edema or effusion

    NARCIS (Netherlands)

    Barkhof, F.; Daams, M.; Scheltens, P.; Brashear, H.R.; Arrighi, H.M.; Bechten, A.K.; Morris, K.; McGovern, M.; Wattjes, M.P.

    2013-01-01

    BACKGROUND AND PURPOSE: Immune therapy against amyloid-Appears to be a promising target in Alzheimer disease. However, a dose-related risk for ARIA on FLAIR images thought to represent parenchymal vasogenic edema or sulcal effusion (termed "ARIA-E"), has been observed in clinical trials. To assess

  15. Comparison of some properties of four provisional restorations resin: Trim, Tempron, Acropars TRII & Duralay (Aria Dent

    Directory of Open Access Journals (Sweden)

    Monzavi A.

    2006-08-01

    Full Text Available Background and Aim: Use of provisional restorations is one of the important phases in the treatment of patients who need fixed prosthesis. Some physical properties are required for these materials. The purpose of this study was the comparison of some physical properties of 4 kinds of resins: Trim, Tempron, Duralay (Aria Dent and Acropars TRII. Materials and Methods: In this experimental study, transverse-strength (TS, setting time (ST, polymerization shrinkage (PS and temperature rise (TR during polymerization were tested. In transverse strength test, 5 samples of each resin were made. TS testing was done with an Instron testing machine. ST testing (5 samples in each group was done with Gilmore needle. In PS test, 11 cylindric samples were prepared from each resin and the shrinkage was examined with digital micrometer (up to 24 hours. In TR test, after mixing the powder and liquid of resins (8 samples in each group, the temperature rise was recorded with 10 seconds interval (up to 15 minutes. Data were analyzed with one-way ANOVA and Tukey HSD tests with p<0.05 as the limit of significance. Results: In TS test, all samples of Trim were bent and no fracture was observed, while Tempron and Duralay showed no significant difference. Both Tempron and Duralay revealed high significant difference with Acropars TRII (P <0.01. In ST test, the difference between groups was significant (P<0.01. The lowest ST was observed in Acropars TRII (7 min, and the highest in Tempron (9.53 min. In PS test, significant difference was observed between Trim and Acropars TRII (P<0.01. PS was completed after 120 min in Tempron and Trim groups. However, PS continued to increase in other groups. In TR test, the difference between groups was significant (P<0.05. Duralay showed the highest TR and the lowest was seen in Trim. Conclusion: In this study, Trim showed better properties than other studied groups. Acropars TRII had the lowest strength. The highest temperature rise

  16. Sulphides balance in tanning leather district in Tuscany: evaluation of H{sub 2}S emissions and estimation of their impact on the air quality of the area; Bilancio dei solfuri nel comprensorio del cuoio: valutazione delle emissioni di dirogeno solforato e del loro impatto sulla qualita' dell'aria della zona

    Energy Technology Data Exchange (ETDEWEB)

    Campi, B.; De Blasi, E.; Vanni, D.; Scali, C. [Pisa Univ., Pisa (Italy). Dipt. di Ingegneria Chimica, Chimica Industriale e Scienza dei Materiali; Spinazzola, A. [ARPAT-Agenzia Regionale per la Protezione Ambientale della Toscana, Pisa (Italy). Dipt. di Protezione Ambientale, Sez. locale di San Romano

    2000-09-01

    The paper deals with an evaluation of hydrogen sulphide emissions from leather tanning industries and water purification plants in the leather district in Tuscany. The aim of the work is to correlate different sources emissions of the area with pollutant concentrations recorded by the monitoring network. Global quantities of treated substances, different plants typologies and operating mode, have been considered, following the indications of the ARPAT's archives. This analysis, updated to 1998, gives interesting information about the trend of emissions and their weight on air quality: the effect of tanning leather industries emissions during the 'pickel' operation results greater than the average purification plants contribution to air quality, even if, cause of the high quantity of treated sulphides, the weight of purification plants remains important. The trend of measured concentration of pollutant in air shows a clear improvement of air quality during last three years (1997-199). [Italian] L'articolo presenta una valutazione delle emissioni di idrogeno sulforato da aziende conciarie e da impianti di trattamento delle acque reflue industriali nel comprensorio del cuoio. in Toscano. Lo scopo dell'indagine e' quello di valutare la possibilita' di correlare le emissioni delle diverse sorgenti della zona con i valori di concentrazione di inquinante al suolo rilevati dlla rete di monitoraggio. La valutazione tiene conto delle quantita' complessive di sostanze lavorate, delle diverse tipologie degli impianti e del loro stato di funzionamento, secondo quanto risulta dai dati contenuti nell'archivio dell'ARPAT (Agenzia Regionale per la Protezione Ambientale della Toscana). L'analisi aggiornata al 1998, fornisce indicazioni circa l'andamento dei fenomeni emissivi ed il loro peso sulla qualita' dell'aria. In particolare si evidenzia come l'effetto delle emissioni dalle aziende conciarie durante l

  17. A comprehensive and sustainable approach to the design of the retrofitting and enlargement of the National Etruscan museum `Pompeo Aria' in Marzabotto, Italy

    Science.gov (United States)

    Mingozzi, Angelo; Bottiglioni, Sergio

    2006-12-01

    The retrofitting and enlargement of National Etruscan Museum `Pompeo Aria' in Marzabotto, Italy is one of the demonstration projects of `MUSEUMS' EC FPV Project that concerns retrofitting and construction of eight European museums in accordance with sustainability principles.The museum was originally placed inside some buildings unsuitable to host exhibitions. As the wrong indoor microclimate could affect objects and boost their deterioration, it was essential to define suitable conditions under which the pieces should be exhibited, and the structures had to be accordingly upgraded to improve their performances.The project aims to balance active systems with bioclimatic strategies and passive solar techniques in order to assure the best conditions for people's comfort and exhibit preventive conservation together with energy savings. In order to succeed in such an attempt, it is essential to define a methodology that helps in managing the complexity, for instance, this has allowed the cross disciplinary team to focus on common priorities and to talk a universal language.In effect, each retrofitting and extension phase followed a preset design method: starting from the site analysis, general and specific targets have been defined, and they have been continuously verified.Methodologies and technical solutions developed and tested during this experience have a great chance of becoming a knowledge platform and being replicated in future interventions.

  18. The Advanced Rapid Imaging and Analysis (ARIA) Project: Providing Standard and On-Demand SAR products for Hazard Science and Hazard Response

    Science.gov (United States)

    Owen, S. E.; Hua, H.; Rosen, P. A.; Agram, P. S.; Webb, F.; Simons, M.; Yun, S. H.; Sacco, G. F.; Liu, Z.; Fielding, E. J.; Lundgren, P.; Moore, A. W.

    2017-12-01

    A new era of geodetic imaging arrived with the launch of the ESA Sentinel-1A/B satellites in 2014 and 2016, and with the 2016 confirmation of the NISAR mission, planned for launch in 2021. These missions assure high quality, freely and openly distributed regularly sampled SAR data into the indefinite future. These unprecedented data sets are a watershed for solid earth sciences as we progress towards the goal of ubiquitous InSAR measurements. We now face the challenge of how to best address the massive volumes of data and intensive processing requirements. Should scientists individually process the same data independently themselves? Should a centralized service provider create standard products that all can use? Are there other approaches to accelerate science that are cost effective and efficient? The Advanced Rapid Imaging and Analysis (ARIA) project, a joint venture co-sponsored by California Institute of Technology (Caltech) and by NASA through the Jet Propulsion Laboratory (JPL), is focused on rapidly generating higher level geodetic imaging products and placing them in the hands of the solid earth science and local, national, and international natural hazard communities by providing science product generation, exploration, and delivery capabilities at an operational level. However, there are challenges in defining the optimal InSAR data products for the solid earth science community. In this presentation, we will present our experience with InSAR users, our lessons learned the advantages of on demand and standard products, and our proposal for the most effective path forward.

  19. Automated measurement of serum thyroxine with the ''AIRA II,'' as compared with competitive protein binding and radioimmunoassay

    International Nuclear Information System (INIS)

    Reese, M.G.; Johnson, L.V.R.

    1978-01-01

    Two conventional serum thyroxine assays, run in separate laboratories, one by competitive protein binding and one by radioimmunoassay, were used to evaluate the automated ARIA II (Becton Dickinson Immunodiagnostics) serum thyroxine assay. Competitive protein binding as compared to ARIA II with 111 clinical serum samples gave a slope of 1.04 and a correlation coefficient of 0.94. The radioimmunoassay comparison to ARIA II with 53 clinical serum samples gave a slope of 1.05 and a correlation coefficient of 0.92. The ARIA II inter-assay coefficient of variation for 10 replicates of low, medium, and high thyroxine serum samples was 6.2, 6.0, and 2.9%, respectively, with an inter-assay coefficient of variation among 15 different assays of 15.5, 10.1, and 7.9%. The automated ARIA II, with a 2.2-min cycle per sample, gives results that compare well with those by manual methodology

  20. Problemas de qualidade no sistema de franqueamento: um estudo de caso em uma vidraçaria no norte do Estado do Tocantins.

    Directory of Open Access Journals (Sweden)

    Rumeninng Abrantes Santos

    2015-08-01

    Full Text Available O presente estudo apresenta uma pesquisa realizada entre o franqueador e o franqueado, com foco na avaliação de desempenho organizacional deste modelo de negócios, cujo ramo abordado foi o de vidraçaria. Este estudo de caso ocorreu em uma empresa no norte do Estado do Tocantins. Para Yin (2001, o estudo de casos é um método indicado quando se deseja explicar questões do tipo “como” ou “por que”, ao mesmo tempo em que haja acessibilidade a pessoas que vivem ou viveram os fatos e estão disponíveis para descreverem o que aconteceu. Adiciona-se ainda à indicação do método, o fato do pesquisador possuir pouco ou nenhum controle sobre o objeto pesquisado. Assim, segundo definição do método pelo próprio autor, “Um estudo de caso é uma investigação empírica que investiga um fenômeno contemporâneo dentro do seu contexto da vida real, especialmente quando os limites entre o fenômeno e o contexto não estão claramente definidos” (Yin, 2001, p. 32. Com a realização da pesquisa, pode-se perceber que o franqueado sofre por falta de apoio da franquia e ainda obteve-se que determinada postura comportamental estabelece melhor relacionamento com o seu franqueador, e que melhor relacionamento entre franqueado e franqueador indica melhor desempenho da unidade franqueada.

  1. Visibility of violence in contemporary Latin-American theater: El año en que nací, by Lola Arias, La mujer puerca y Mau Mau, o la tercera parte de la noche, by Santiago Loza

    Directory of Open Access Journals (Sweden)

    Júlia Morena Costa

    2016-12-01

    Full Text Available From the three works by two Argentinean authors, we reflect on two aesthetic and political possibilities of contemporary dramaturgies that produce collective and individual memories and traumas. From a dramaturgy of the author, in La mujer puerca (Santiago Loza the principles that sustain the normative platforms of Latin-American societies are questioned and in Mau Mau, o la tercera parte de la noche (also by Santiago Loza two women, witnesses of the glamour of the 1960’s, wander around from endless parties joined to the most violent repression and the decadence at the return of democracy. In El año en que nací, by Lola Arias, the performers use personal documents and objects to reconstruct collectively experiences of the Chilean dictatorship (1973-1990. Causing tension between the boundaries of the fictional and the biographical, the dramaturgy articulates the textuality of this youth that asks for a place in the process of reconstruction of a socially jeopardized present.

  2. Reference: 129 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ried out two-hybrid screens to identify signaling components that modulate ABA-responsive gene expression. E...mploying a transcription factor, ABF2, which controls the ABA-dependent gene expression via the G-box type A...n. The physiological relevance of ABF2-ARIA interaction was supported by their similar express...ion patterns and similar subcellular localization. Plants overexpressing ARIA are hypersensitiv...y contrast, an ARIA knockout mutant exhibits ABA and glucose insensitivities. Changes in the expression leve

  3. Characteristics of soil-to-plant transfer of elements relevant to radioactive waste in boreal forest

    Energy Technology Data Exchange (ETDEWEB)

    Roivainen, P.

    2011-07-01

    The use of nuclear energy generates large amounts of different types of radioactive wastes that can be accidentally released into the environment. Soil-to-plant transfer is a key process for the dispersion of radionuclides in the biosphere and is usually described by a concentration ratio (CR) between plant and soil concentrations in radioecological models. Our knowledge of the soil-to-plant transfer of many radionuclides is currently limited and concerns mainly agricultural species and temperate environments. The validity of radioecological modelling is affected by the accuracy of the assumptions and parameters used to describe soil-to-plant transfer. This study investigated the soil-to-plant transfer of six elements (cobalt (Co), molybdenum (Mo), nickel (Ni), lead (Pb), uranium (U) and zinc (Zn)) relevant to radioactive waste at two boreal forest sites and assessed the factors affecting the CR values. May lily (Maianthemum bifolium), narrow buckler fern (Dryopteris carthusiana) and blueberry (Vaccinium myrtillus) were selected as representatives of understory species, while rowan (Sorbus aucuparia) and Norway spruce (Picea abies) represented trees in this study. All the elements studied were found to accumulate in plant roots, indicating that separate CR values for root and aboveground plant parts are needed. The between-species variation in CR values was not clearly higher than the within-species variation, suggesting that the use of generic CR values for understory species and trees is justified. No linear relationship was found between soil and plant concentrations for the elements studied and a non-linear equation was found to be the best for describing the dependence of CR values on soil concentration. Thus, the commonly used assumption of a linear relationship between plant and soil concentrations may lead to underestimation of plant root uptake at low soil concentrations. Plant nutrients potassium, magnesium, manganese, phosphorus and sulphur were found to

  4. Patterns of late spring frost leaf damage and recovery in a European beech (Fagus sylvatica L.) stand in south-eastern Germany based on repeated digital photographs.

    Science.gov (United States)

    Menzel, Annette; Helm, Raimund; Zang, Christian

    2015-01-01

    Damage by late spring frost is a risk deciduous trees have to cope with in order to optimize the length of their growing season. The timing of spring phenological development plays a crucial role, not only at the species level, but also at the population and individual level, since fresh new leaves are especially vulnerable. For the pronounced late spring frost in May 2011 in Germany, we studied the individual leaf development of 35 deciduous trees (mainly European beech Fagus sylvatica L.) at a mountainous forest site in the Bayerischer Wald National Park using repeated digital photographs. Analyses of the time series of greenness by a novel Bayesian multiple change point approach mostly revealed five change points which almost perfectly matched the expected break points in leaf development: (i) start of the first greening between day of the year (DOY) 108-119 (mean 113), (ii) end of greening, and (iii) visible frost damage after the frost on the night of May 3rd/4th (DOY 123/124), (iv) re-sprouting 19-38 days after the frost, and (v) full maturity around DOY 178 (166-184) when all beech crowns had fully recovered. Since frost damage was nearly 100%, individual susceptibility did not depend on the timing of first spring leaf unfolding. However, we could identify significant patterns in fitness linked to an earlier start of leaf unfolding. Those individuals that had an earlier start of greening during the first flushing period had a shorter period of recovery and started the second greening earlier. Thus, phenological timing triggered the speed of recovery from such an extreme event. The maximum greenness achieved, however, did not vary with leaf unfolding dates. Two mountain ashes (Sorbus aucuparia L.) were not affected by the low temperatures of -5°C. Time series analysis of webcam pictures can thus improve process-based knowledge and provide valuable insights into the link between phenological variation, late spring frost damage, and recovery within one stand.

  5. Characteristics of soil-to-plant transfer of elements relevant to radioactive waste in boreal forest

    International Nuclear Information System (INIS)

    Roivainen, P.

    2011-01-01

    The use of nuclear energy generates large amounts of different types of radioactive wastes that can be accidentally released into the environment. Soil-to-plant transfer is a key process for the dispersion of radionuclides in the biosphere and is usually described by a concentration ratio (CR) between plant and soil concentrations in radioecological models. Our knowledge of the soil-to-plant transfer of many radionuclides is currently limited and concerns mainly agricultural species and temperate environments. The validity of radioecological modelling is affected by the accuracy of the assumptions and parameters used to describe soil-to-plant transfer. This study investigated the soil-to-plant transfer of six elements (cobalt (Co), molybdenum (Mo), nickel (Ni), lead (Pb), uranium (U) and zinc (Zn)) relevant to radioactive waste at two boreal forest sites and assessed the factors affecting the CR values. May lily (Maianthemum bifolium), narrow buckler fern (Dryopteris carthusiana) and blueberry (Vaccinium myrtillus) were selected as representatives of understory species, while rowan (Sorbus aucuparia) and Norway spruce (Picea abies) represented trees in this study. All the elements studied were found to accumulate in plant roots, indicating that separate CR values for root and aboveground plant parts are needed. The between-species variation in CR values was not clearly higher than the within-species variation, suggesting that the use of generic CR values for understory species and trees is justified. No linear relationship was found between soil and plant concentrations for the elements studied and a non-linear equation was found to be the best for describing the dependence of CR values on soil concentration. Thus, the commonly used assumption of a linear relationship between plant and soil concentrations may lead to underestimation of plant root uptake at low soil concentrations. Plant nutrients potassium, magnesium, manganese, phosphorus and sulphur were found to

  6. Species-Specific Morphological and Physiological Responses of Four Korean Native Trees Species under Elevated CO2 Concentration using Open Top Chamber

    Science.gov (United States)

    Song, W.; Byeon, S.; Lee, H.; Lee, M.; Lim, H.; Kim, H. S.

    2017-12-01

    For the last three years, studies on the morphological and physiological characteristics were carried out for four tree species (Pinus densiflora, Quercus acutissima, Sorbus alnifolia and Fraxinus rhynchophylla) which are representative native species of Korea. We used a control site and three open top chambers (con, chamber 1, 2, and 3) which were exposed to ambient and two elevated CO2 concentration ([CO2]); the concentration were the ambient (400ppm) for control and chamber 1 and 1.4 times (560ppm) and 1.8 times (720 ppm) of the atmosphere for chamber 2 and 3, respectively. Leaf mass per area (LMA), stomatal size, density and area were examined to investigate the morphological changes of the trees. Among four species, F. rhynchophylla increased their LMA with increase of CO2 concentration. In addition, F. rhynchophylla showed the decrease of stomatal density significantly (p-value=0.02), while there was no difference in stoma size. These findings resulted in 25.5% and 38.7% decrease of stomata area per unit leaf area calculated by multiplying the size and density of the stomata. On the other hand, all 4 tree species were significantly increased in height and diameter growth with the elevated CO2. However, in the case of Q. acutissima, the increase in height growth was prominent. For physiological characteristics, the maximum photosynthetic rate was faster in the chambers exposed to high [CO2] than that in the control. However the rate of carboxylation and the electron transfer rate showed no particular tendency. The measurement of hydraulic conductivity (Ks, kg/m/s/Mpa) for Crataegus pinnatifida, increased as the [CO2] in the atmosphere increased, and the 50% Loss Conductance (Mpa) tended to increase slightly with the [CO2]. The correlation analysis between hydraulic conductivity and vulnerability to cavitation showed a strong negative correlation (P <0.05), which was unlike the general tendency.

  7. PENGARUH MODEL PEMBELAJARAN ASSURANCE, RELEVANCE, INTEREST, ASSESSMENT, SATISFACTION DENGAN STRATEGI ACTIVE LEARNING TIPE INDEX CARD MATCH TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIK SISWA SMA

    Directory of Open Access Journals (Sweden)

    Frasticha Frasticha

    2016-08-01

    Full Text Available Pemecahan masalah merupakan kegiatan matematika yang sulit baik dalam mempelajari maupun mengajarkannya, sehingga diperlukan adanya suatu model pembelajaran yang dapat memberikan pengaruh positif terhadap kemampuan pemecahan masalah siswa. Salah satu model pembelajaran yang dapat digunakan yaitu model pembelajaran ARIAS dengan strategi active learning tipe ICM. Penelitian ini bertujuan untuk mengetahui: (1 model pembelajaran ARIAS dengan strategi active learning tipe ICM berpengaruh terhadap kemampuan pemecahan masalah matematik siswa SMA; (2 Sikap siswa terhadap pembelajaran matematika menggunakan model pembelajaran ARIAS dengan strategi active learning tipe ICM. Subjek penelitian ini adalah siswa kelas XI IPA 1 dengan jumlah 38 siswa sebagai kelas kontrol dan XI IPA 2 dengan jumlah 39 siswa sebagai kelas eksperimen di SMAN 19 Kabupaten Tangerang pada tahun ajaran 2015-2016. Metode penelitian yang digunakan adalah metode penelitian eksperimen dengan adalah desain kuasi eksperimen dengan bentuk Nonequivalent Control Group serta Cluster Sampling sebagai teknik pengambilan sampel. Analisis data dalam penelitian ini menggunakan SPSS Statistics Version 22. Hasil penelitian :(1 model pembelajaran ARIAS dengan strategi active learning tipe ICM berpengaruh terhadap kemampuan pemecahan masalah matematik siswa SMA dan memberikan pengaruh yang positif; (2 sikap siswa positif terhadap model pembelajaran ARIAS dengan strategi active learning tipe ICM. Kata Kunci: Assurance Relevance Interest Assessment Satisfaction, Index Card Match, Kemampuan Pemecahan Masalah

  8. A comparison of automated and manual radioimmunoassays for the estimation of serum digoxin

    International Nuclear Information System (INIS)

    Tuttlebee, J.W.

    1984-01-01

    Digoxin was assayed manually (SPAC kit) and by an automated radioimmunoassay instrument (ARIA II). There was good correlation between the methods (r=0.964; n=120). Carryover by the automated method was marginally significant from low to high level samples (5.2%), but insignificant from high to low level samples (1.4%). The precision on the ARIA II was far better in spite of the fact that assays were performed only in singlets compared with duplicates on the manual procedure. Best precision was obtained at the high level (3.76 nmol/l; between-batch CV: 2.4% ARIA; 5.5% SPAC). All values for control samples (manual and automated) fell within 6% of the all-method means. Using the ARIA II is marginally quicker and significantly cheaper. However, some back-up procedure is required for 'down time' with the machine, for what can be an urgent investigation. Patient results correlated well with clinical data. (orig.) [de

  9. QGM Research Report

    DEFF Research Database (Denmark)

    Schaetz, Florian

    2014-01-01

    I outlined my joint work with Camilo Arias Abad (Max Planck Institute, Bonn) on higher holonomies for flat superconnections and explained some background material.......I outlined my joint work with Camilo Arias Abad (Max Planck Institute, Bonn) on higher holonomies for flat superconnections and explained some background material....

  10. Instrumental shaking thresholds for seismically induced landslides and preliminary report on landslides triggered by the October 17, 1989, Loma Prieta, California earthquake

    Science.gov (United States)

    Harp, E.L.

    1993-01-01

    The generation of seismically induced landslide depends on the characteristics of shaking as well as mechanical properties of geologic materials. A very important parameter in the study of seismically induced landslide is the intensity based on a strong-motion accelerogram: it is defined as Arias intensity and is proportional to the duration of the shaking record as well as the amplitude. Having a theoretical relationship between Arias intensity, magnitude and distance it is possible to predict how far away from the seismic source landslides are likely to occur for a given magnitude earthquake. Field investigations have established that the threshold level of Arias intensity depends also on site effects, particularly the fracture characteristics of the outcrops present. -from Author

  11. Automated Diabetic Retinopathy Image Assessment Software: Diagnostic Accuracy and Cost-Effectiveness Compared with Human Graders.

    Science.gov (United States)

    Tufail, Adnan; Rudisill, Caroline; Egan, Catherine; Kapetanakis, Venediktos V; Salas-Vega, Sebastian; Owen, Christopher G; Lee, Aaron; Louw, Vern; Anderson, John; Liew, Gerald; Bolter, Louis; Srinivas, Sowmya; Nittala, Muneeswar; Sadda, SriniVas; Taylor, Paul; Rudnicka, Alicja R

    2017-03-01

    With the increasing prevalence of diabetes, annual screening for diabetic retinopathy (DR) by expert human grading of retinal images is challenging. Automated DR image assessment systems (ARIAS) may provide clinically effective and cost-effective detection of retinopathy. We aimed to determine whether ARIAS can be safely introduced into DR screening pathways to replace human graders. Observational measurement comparison study of human graders following a national screening program for DR versus ARIAS. Retinal images from 20 258 consecutive patients attending routine annual diabetic eye screening between June 1, 2012, and November 4, 2013. Retinal images were manually graded following a standard national protocol for DR screening and were processed by 3 ARIAS: iGradingM, Retmarker, and EyeArt. Discrepancies between manual grades and ARIAS results were sent to a reading center for arbitration. Screening performance (sensitivity, false-positive rate) and diagnostic accuracy (95% confidence intervals of screening-performance measures) were determined. Economic analysis estimated the cost per appropriate screening outcome. Sensitivity point estimates (95% confidence intervals) of the ARIAS were as follows: EyeArt 94.7% (94.2%-95.2%) for any retinopathy, 93.8% (92.9%-94.6%) for referable retinopathy (human graded as either ungradable, maculopathy, preproliferative, or proliferative), 99.6% (97.0%-99.9%) for proliferative retinopathy; Retmarker 73.0% (72.0 %-74.0%) for any retinopathy, 85.0% (83.6%-86.2%) for referable retinopathy, 97.9% (94.9%-99.1%) for proliferative retinopathy. iGradingM classified all images as either having disease or being ungradable. EyeArt and Retmarker saved costs compared with manual grading both as a replacement for initial human grading and as a filter prior to primary human grading, although the latter approach was less cost-effective. Retmarker and EyeArt systems achieved acceptable sensitivity for referable retinopathy when compared

  12. Statistical elements in calculations procedures for air quality control; Elementi di statistica nelle procedure di calcolo per il controllo della qualita' dell'aria

    Energy Technology Data Exchange (ETDEWEB)

    Mura, M.C. [Istituto Superiore di Sanita' , Laboratorio di Igiene Ambientale, Rome (Italy)

    2001-07-01

    The statistical processing of data resulting from the monitoring of chemical atmospheric pollution aimed at air quality control is presented. The form of procedural models may offer a practical instrument to the operators in the sector. The procedural models are modular and can be easily integrated with other models. They include elementary calculation procedures and mathematical methods for statistical analysis. The calculation elements have been developed by probabilistic induction so as to relate them to the statistical analysis. The calculation elements have been developed by probabilistic induction so as to relate them to the statistical models, which are the basis of the methods used for the study and the forecast of atmospheric pollution. This report is part of the updating and training activity that the Istituto Superiore di Sanita' has been carrying on for over twenty years, addressed to operators of the environmental field. [Italian] Il processo di elaborazione statistica dei dati provenienti dal monitoraggio dell'inquinamento chimico dell'atmosfera, finalizzato al controllo della qualita' dell'aria, e' presentato in modelli di procedure al fine di fornire un sintetico strumento di lavoro agli operatori del settore. I modelli di procedure sono modulari ed integrabili. Includono gli elementi di calcolo elementare ed i metodi statistici d'analisi. Gli elementi di calcolo sono sviluppati con metodo d'induzione probabilistica per collegarli ai modelli statistici, che sono alla base dei metodi d'analisi nello studio del fenomeno dell'inquinamento atmosferico anche a fini previsionali. Il rapporto si inserisce nell'attivita' di aggiornamento e di formazione che fin dagli anni ottanta l'Istituto Superiore di Sanita' indirizza agli operatori del settore ambientale.

  13. Searching Sinks and Sources: CO2 Fluxes Before and After Partial Deforestation of a Spruce Forest

    Science.gov (United States)

    Ney, P.; Graf, A.; Druee, C.; Esser, O.; Klosterhalfen, A.; Valler, V.; Pick, K.; Vereecken, H.

    2017-12-01

    Forest ecosystems in the northern mid-latitudes act as a sink for atmospheric carbon dioxide (CO2) and hence play an important role in the terrestrial carbon cycle. Disturbances of these landscapes may have a significant impact on their ecosystem carbon budget. We present seven years of eddy covariance (EC) measurements (September 2013 to September 2017) over a 70 year old spruce stock, including three years prior to and four years after partial deforestation. We analyzed the seasonal and inter-annual changes of carbon fluxes as affected mainly by the forest transition. The measurements were carried out in a small headwater catchment (38.5 ha) within the TERENO (TERrestrial Environmental Observatories) network in the Eifel National Park Germany (50°30'N, 06°19'E, 595-629 m a.s.l.). An EC system, mounted on the top of a 38 m high tower, continuously samples fluxes of momentum, sensible heat, latent heat and CO2. In August and September 2013, more than 20% of the catchment was deforested and planned for regeneration towards natural deciduous vegetation, and a second EC station (2.5 m height) was installed in the middle of this clearcut. Flux partitioning and gap filling methods were used to calculate full time series and annual carbon budgets of the measured net ecosystem exchange (NEE) and its components gross primary production (GPP) and total ecosystem respiration (Reco). Additionally, soil respiration was measured with manual chambers on a monthly to bi-monthly basis at 25 transect points in the forest and deforested area. Annual sums of NEE represent the forest as a carbon sink with small inter-annual variability. In contrast, the deforested area showed a clear trend. In the first year after partial deforestation, regrowth on the deforested area consisted mainly of grasses and red foxglove (Digitalis purpurea L.), while since the second year also growth of mountain ash (Sorbus aucuparia L.) and broom (Cytisus scoparius L.) increased. The regrowth of biomass is

  14. Die musiktheoretische Ergründung der Arienform in italienischen Opern des 18. Jahrhunderts und die Umgestaltung des Fachs Formenlehre

    Directory of Open Access Journals (Sweden)

    Irina Susidko

    2015-12-01

    Full Text Available The paper focuses on the issue of the role played by the 18th Century Italian aria within the general system of musical forms. This question is relevant for both music theory and pedagogy. Did the aria influence instrumental genres or was it the opposite?Throughout the history of professional musical education in Russia (from the 19th century to the present day, both general music theory and courses in musical form have usually been based on instrumental music. However, studies in recent decades show that, in the process of crystallization of a number of structures and principles of composition in the first half of the 18th century, the aria takes a prominent position. Among these are such principles as the ritornello, which underlies the Baroque concerto; principles of recapitulation and ternary form that became established in Italian arias in the 1680s (earlier than in the instrumental genres, as well as the principle of thematic contrast. Italian opera played a key role in the formation of classical musical Thematik (Ger. - not only in its lexical topoi, but also in the treatment of homophony, metric and syntactic periodicity, and the fractionality of motivic structure. The development of the two-subjects sonata form took place within the framework of da capo arias simultaneously with instrumental music (1720-1750s. The Italian aria played a decisive role in the birth of the sonata form with two initial sections typical of the classic concerto.In the musical form course for musicologists and musicians-performers at the Russian Gnessins Academy of Music, I discuss the theory and history of music forms during the 17th and 18 th centuries, taking into account all these factors. This method introduces significant adjustments in the traditional practice of music form teaching in Russia, thereby bringing the understanding of students closer to the real processes that occurred in the music history of the 18th century.

  15. Monitoring Blood-Brain Barrier Integrity Following Amyloid-β Immunotherapy Using Gadolinium-Enhanced MRI in a PDAPP Mouse Model.

    Science.gov (United States)

    Blockx, Ines; Einstein, Steve; Guns, Pieter-Jan; Van Audekerke, Johan; Guglielmetti, Caroline; Zago, Wagner; Roose, Dimitri; Verhoye, Marleen; Van der Linden, Annemie; Bard, Frederique

    2016-09-06

    Amyloid-related imaging abnormalities (ARIA) have been reported with some anti-amyloid-β (Aβ) immunotherapy trials. They are detected with magnetic resonance imaging (MRI) and thought to represent transient accumulation of fluid/edema (ARIA-E) or microhemorrhages (ARIA-H). Although the clinical significance and pathophysiology are unknown, it has been proposed that anti-Aβimmunotherapy may affect blood-brain barrier (BBB) integrity. To examine vascular integrity in aged (12-16 months) PDAPP and wild type mice (WT), we performed a series of longitudinal in vivo MRI studies. Mice were treated on a weekly basis using anti-Aβimmunotherapy (3D6) and follow up was done longitudinally from 1-12 weeks after treatment. BBB-integrity was assessed using both visual assessment of T1-weighted scans and repeated T1 mapping in combination with gadolinium (Gd-DOTA). A subset of 3D6 treated PDAPP mice displayed numerous BBB disruptions, whereas WT and saline-treated PDAPP mice showed intact BBB integrity under the conditions tested. In addition, the contrast induced decrease in T1 value was observed in the meningeal and midline area. BBB disruption events occurred early during treatment (between 1 and 5 weeks), were transient, and resolved quickly. Finally, BBB-leakages associated with microhemorrhages were confirmed by Perls'Prussian blue histopathological analysis. Our preclinical findings support the hypothesis that 3D6 leads to transient leakage from amyloid-positive vessels. The current study has provided valuable insights on the time course of vascular alterations during immunization treatment and supports further research in relation to the nature of ARIA and the utility of in vivo repeated T1 MRI as a translational tool.

  16. Beam Dynamics for ARIA

    Energy Technology Data Exchange (ETDEWEB)

    Ekdahl, Carl August Jr. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-10-14

    Beam dynamics issues are assessed for a new linear induction electron accelerator being designed for flash radiography of large explosively driven hydrodynamic experiments. Special attention is paid to equilibrium beam transport, possible emittance growth, and beam stability. It is concluded that a radiographic quality beam will be produced possible if engineering standards and construction details are equivalent to those on the present radiography accelerators at Los Alamos.

  17. Getting Started: Using a Global Circumnavigation Balloon Flight to Explore Picosatellite (CubeSat) Technology

    OpenAIRE

    Bennett, Keith; Swartwout, Michael; Tobias, Barry; McNally, Patrick

    2001-01-01

    Washington University's Project Aria is currently involved in the CubeSat program. Project Aria is a student-led engineering education, research, and K-12 outreach program. The project’s CubeSat goal is the development of a spherical imaging spacecraft, the "Palantir", ready for launch in late 2002. Recently, the Palantir team was offered the opportunity to fly a small payload on a global circumnavigation balloon flight in mid-2001. The payload would collect atmospheric data such as temperatu...

  18. [Aβ immunotherapy for Alzheimer's disease].

    Science.gov (United States)

    Sakai, Kenji; Yamada, Masahito

    2013-04-01

    Alzheimer's disease (AD) is one of the neurodegenerative diseases characterized by the deposition of amyloid-β-protein (Aβ) as senile plaques in the brain parenchyma and phosphorylated-tau accumulation as neurofibrillary tangles in the neurons. Although details of the disease pathomechanisms remain unclear, Aβ likely acts as a key protein for AD initiation and progression, followed by abnormal tau phosphorylation and neuronal death (amyloid-cascade hypothesis). According to this hypothesis, Aβ immunization therapies are created to eliminate Aβ from the brain, and to prevent the neurons from damage by these pathogenic proteins. There are two methods for Aβ immunotherapies: active and passive immunization. Previous studies have shown Aβ removal and improved cognitive function in animal models of AD. Clinical trials on various drugs, including AN1792, bapineuzumab, and solanezumab, have been carried out; however, all trials have failed to demonstrate apparent clinical benefits. On the contrary, side effects emerged, such as meningoencephalitis, vasogenic edema, which are currently called amyloid related imaging abnormalities (ARIA)-E and microhemorrhage (ARIA-H). In neuropathological studies of immunized cases, Aβ was removed from the brain parenchyma and phosphorylated-tau was reduced in the neuronal processes. Moreover, deterioration of the cerebral amyloid angiopathy (CAA) and an increase of microhemorrhages and microinfarcts were described. Aβ is cleared from the brain mainly via the lymphatic drainage pathway. ARIA could stem from severe CAA due to dysfunction of the drainage pathway after immunotherapy. Aβ immunization has a potential of cure for AD patients, although the above-described problems must be overcome before applying this therapy in clinical treatment.

  19. A Question of Honor(aria

    Directory of Open Access Journals (Sweden)

    John L Wallace

    2001-01-01

    Full Text Available Honorarium: fee, especially for professional services normally rendered without payment (Oxford English Dictionary One of the main activities of the Canadian Association of Gastroenterology (CAG is the organizing of professional education events, and the largest of these events is Canadian Digestive Diseases Week (CDDW. The CDDW is organized by members of the CAG for members of the CAG. The funds needed to run this meeting are generated from a number of sources - membership dues, sponsorship from pharmaceutical companies, sale of exhibit space, etc. These funds are used to pay for the convention facilities, for the audiovisual services, for the coffee breaks and lunches, and for the cost of bringing to our meetings the many experts who are on the program.

  20. Vascular alterations in PDAPP mice after anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities.

    Science.gov (United States)

    Zago, Wagner; Schroeter, Sally; Guido, Teresa; Khan, Karen; Seubert, Peter; Yednock, Ted; Schenk, Dale; Gregg, Keith M; Games, Dora; Bard, Frédérique; Kinney, Gene G

    2013-10-01

    Clinical studies of β-amyloid (Aβ) immunotherapy in Alzheimer's disease (AD) patients have demonstrated reduction of central Aβ plaque by positron emission tomography (PET) imaging and the appearance of amyloid-related imaging abnormalities (ARIA). To better understand the relationship between ARIA and the pathophysiology of AD, we undertook a series of studies in PDAPP mice evaluating vascular alterations in the context of central Aβ pathology and after anti-Aβ immunotherapy. We analyzed PDAPP mice treated with either 3 mg/kg/week of 3D6, the murine form of bapineuzumab, or isotype control antibodies for periods ranging from 1 to 36 weeks and evaluated the vascular alterations in the context of Aβ pathology and after anti-Aβ immunotherapy. The number of mice in each treatment group ranged from 26 to 39 and a total of 345 animals were analyzed. The central vasculature displayed morphological abnormalities associated with vascular Aβ deposits. Treatment with 3D6 antibody induced clearance of vascular Aβ that was spatially and temporally associated with a transient increase in microhemorrhage and in capillary Aβ deposition. Microhemorrhage resolved over a time period that was associated with a recovery of vascular morphology and a decrease in capillary Aβ accumulation. These data suggest that vascular leakage events, such as microhemorrhage, may be related to the removal of vascular Aβ. With continued treatment, this initial susceptibility period is followed by restoration of vascular morphology and reduced vulnerability to further vascular leakage events. The data collectively suggested a vascular amyloid clearance model of ARIA, which accounts for the currently known risk factors for the incidence of ARIA in clinical studies. Copyright © 2013. Published by Elsevier Inc.

  1. Links between operating experience feedback of industrial accidents and nuclear safety

    International Nuclear Information System (INIS)

    Eury, S.P.

    2012-01-01

    Since 1992, the bureau for analysis of industrial risks and pollutions (BARPI) collects, analyzes and publishes information on industrial accidents. The ARIA database lists over 40.000 accidents or incidents, most of which occurred in French classified facilities (ICPE). Events occurring in nuclear facilities are rarely reported in ARIA because they are reported in other databases. This paper describes the process of selection, characterization and review of these accidents, as well as the following consultation with industry trade groups. It is essential to publicize widely the lessons learned from analyzing industrial accidents. To this end, a web site (www.aria.developpement-durable.gouv.fr) gives free access to the accidents summaries, detailed sheets, studies, etc. to professionals and the general public. In addition, the accidents descriptions and characteristics serve as inputs to new regulation projects or risk analyses. Finally, the question of the links between operating experience feedback of industrial accidents and nuclear safety is explored: if the rigorous and well-documented methods of experience feedback in the nuclear field certainly set an example for other activities, nuclear safety can also benefit from inputs coming from the vast diversity of accidents arisen into industrial facilities because of common grounds. Among these common grounds we can find: -) the fuel cycle facilities use many chemicals and chemical processes that are also used by chemical industries; -) the problems resulting from the ageing of equipment affect both heavy and nuclear industries; -) the risk of hydrogen explosion; -) the risk of ammonia, ammonia is a gas used by nuclear power plants as an ingredient in the onsite production of mono-chloramine and ammonia is involved in numerous accidents in the industry: at least 900 entries can be found in the ARIA database. The paper is followed by the slides of the presentation

  2. GPS Position Time Series @ JPL

    Science.gov (United States)

    Owen, Susan; Moore, Angelyn; Kedar, Sharon; Liu, Zhen; Webb, Frank; Heflin, Mike; Desai, Shailen

    2013-01-01

    Different flavors of GPS time series analysis at JPL - Use same GPS Precise Point Positioning Analysis raw time series - Variations in time series analysis/post-processing driven by different users. center dot JPL Global Time Series/Velocities - researchers studying reference frame, combining with VLBI/SLR/DORIS center dot JPL/SOPAC Combined Time Series/Velocities - crustal deformation for tectonic, volcanic, ground water studies center dot ARIA Time Series/Coseismic Data Products - Hazard monitoring and response focused center dot ARIA data system designed to integrate GPS and InSAR - GPS tropospheric delay used for correcting InSAR - Caltech's GIANT time series analysis uses GPS to correct orbital errors in InSAR - Zhen Liu's talking tomorrow on InSAR Time Series analysis

  3. Siidiid / Kreete Reval

    Index Scriptorium Estoniae

    Reval, Kreete

    2002-01-01

    Uutest plaatidest Erich Krieger "Tere hommikust Eestimaa", Pet Shop Boys "Release", Ultima Thule "Kogutud teosed 1987-2002", The Gentle People "Soundtracks for Living", Cecilia Bartoli "Gluck Italian Arias"

  4. Effect of wood ash and K-fertilization on {sup 137}Cs uptake by selected forest plants

    Energy Technology Data Exchange (ETDEWEB)

    Mandro, Yrii N. [Zhytomyr State Technological University, P.O. Box 10005 Zhytomyr (Ukraine); Rosen, Klas [Swedish University of Agricultural Sciences P.O. Box 7070 SE-750 07 Uppsala (Sweden); Vinichuk, Mykhailo M. [Zhytomyr State Technological University, P.O. Box 10005 Zhytomyr (Ukraine); Swedish University of Agricultural Sciences P.O. Box 7070 SE-750 07 Uppsala (Sweden)

    2014-07-01

    Accumulation {sup 137}Cs by different forest plants and trees after fertilization of soil with potassium and wood ash ({sup 137}Cs-contaminated and non-contaminated) in forest ecosystems of Ukraine contaminated by radionuclides after Chernobyl accident in 1986 was studied. Experiment is performed in Bazar forestry, Zhytomyr region, Ukraine, located about 70 km (51 deg. 5'35'' N, 29 deg. 18'56'' E) from Chernobyl NPP. Potassium fertilizer (KCl, wooden ash (Ash), and {sup 137}Cs-contaminated ash ({sup 137}CsAsh) in different combinations) were spread on the forest floor in April 2012 at a rate corresponding 100 kg/ha potassium. The experiment layout was as follows: 1- Control (no fertilizers were applied), 2- KCl, 3- Ash + KCl, 4- Ash + {sup 137}CsAsh, 5- Ash, 6- {sup 137}CsAsh + KCl. Samples (leaves and annual shoots) of blueberry (Vaccinium myrtillus), cowberry (Vaccinium vitis-idaea), rowan (Sorbus aucuparia), birch (Betula), buckthorn (Frangula) and oak (Quercus robur) and also mushrooms (fruit bodies of Russula, Lactarius, Cantharellus, Collybia etc.) and berries (blueberry and cowberry) were taken monthly from each treatment. Samples were measured for {sup 137}Cs with calibrated HPGe detectors. The results of the first year studies show variation of Transfer Factors (TF) for different plants and for the same plants on different treatments. The effect of fertilization was found for blueberry on Ash-applicated (TF = 0.0085 ± 0.0025), {sup 137}CsAsh + KCl-applicated (TF = 0.0105 ± 0.0060) and Ash + KCl-applicated (TF = 0.0123 ± 0.0058) treatments compared to Control (TF = 0.0163 ± 0.0092). Also good effect for rowan on Ash + KCl-applicated treatment (TF = 0.0067 ± 0.0024) compared to Control (TF = 0.0100 ± 0.0064). Effect was less obvious for birch on Ash + KCl-applicated treatment and for cowberry on Ash + KCl-applicated treatment. There was not found an obvious effect of fertilization for buckthorn. Positive effect of

  5. Sierra/Aria 4.48 Verification Manual.

    Energy Technology Data Exchange (ETDEWEB)

    Sierra Thermal Fluid Development Team

    2018-04-01

    Presented in this document is a portion of the tests that exist in the Sierra Thermal/Fluids verification test suite. Each of these tests is run nightly with the Sierra/TF code suite and the results of the test checked under mesh refinement against the correct analytic result. For each of the tests presented in this document the test setup, derivation of the analytic solution, and comparison of the code results to the analytic solution is provided. This document can be used to confirm that a given code capability is verified or referenced as a compilation of example problems.

  6. New Releases

    Index Scriptorium Estoniae

    2005-01-01

    Heliplaatidest: Giya Kancheli "In l'istesso tempo" (plaadil ka Kremerata Baltica), Various Cpsrs "Op. arias" (laulab Miliza Korjus), Various Cpsrs "Ob con Forca" (dirigeerib Arvo Volmer), "Anu Tali. Rahmaninov. Sibelius. Tüür"

  7. Plaadid / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2003-01-01

    Uutest plaatidest TLC "3D", Audioslave "Audioslave", Too "Through The Looking Glass", Dave Hollister "Things in the Game...", Erik Sermon "React", Family "We Are Family", Eric Clapton "One More Car...", Gianna Nannini "Aria"

  8. The Synthetic Aperture Radar Science Data Processing Foundry Concept for Earth Science

    Science.gov (United States)

    Rosen, P. A.; Hua, H.; Norton, C. D.; Little, M. M.

    2015-12-01

    Since 2008, NASA's Earth Science Technology Office and the Advanced Information Systems Technology Program have invested in two technology evolutions to meet the needs of the community of scientists exploiting the rapidly growing database of international synthetic aperture radar (SAR) data. JPL, working with the science community, has developed the InSAR Scientific Computing Environment (ISCE), a next-generation interferometric SAR processing system that is designed to be flexible and extensible. ISCE currently supports many international space borne data sets but has been primarily focused on geodetic science and applications. A second evolutionary path, the Advanced Rapid Imaging and Analysis (ARIA) science data system, uses ISCE as its core science data processing engine and produces automated science and response products, quality assessments and metadata. The success of this two-front effort has been demonstrated in NASA's ability to respond to recent events with useful disaster support. JPL has enabled high-volume and low latency data production by the re-use of the hybrid cloud computing science data system (HySDS) that runs ARIA, leveraging on-premise cloud computing assets that are able to burst onto the Amazon Web Services (AWS) services as needed. Beyond geodetic applications, needs have emerged to process large volumes of time-series SAR data collected for estimation of biomass and its change, in such campaigns as the upcoming AfriSAR field campaign. ESTO is funding JPL to extend the ISCE-ARIA model to a "SAR Science Data Processing Foundry" to on-ramp new data sources and to produce new science data products to meet the needs of science teams and, in general, science community members. An extension of the ISCE-ARIA model to support on-demand processing will permit PIs to leverage this Foundry to produce data products from accepted data sources when they need them. This paper will describe each of the elements of the SAR SDP Foundry and describe their

  9. Epilepsy Surgery for Individuals with TSC

    Science.gov (United States)

    ... Privacy Policy Sitemap Learn Engage Donate About TSC Epilepsy Surgery for Individuals with TSC In this video ... Aria Fallah, MD, discusses the surgical treatment of epilepsy in children with tuberous sclerosis complex. Epilepsy is ...

  10. Epilepsy Surgery for Individuals with TSC

    Science.gov (United States)

    ... this video dated June 1, 2017, UCLA pediatric neurosurgeon Aria Fallah, MD, discusses the surgical treatment of ... the epilepsy surgery team, which includes the epileptologist, neurosurgeon, neuroradiologists and neuropsychologists, reviews all the collected data ...

  11. OS GRUPOS INDÍGENAS E OS DOCES BRASILEIROS

    Directory of Open Access Journals (Sweden)

    MÁRTIN CÉSAR TEMPASS

    2008-12-01

    Full Text Available ABSTRACT: In the books of Gilberto Freyre and Câmara Cascudo, that influencied so much the literature about brazilian alimentation, the participation of indigenous groups in the national sweets formation process is negligencied. However, is possible to find in book´s“interlineations” of these two authors valuables informations about indigenous contributions to this process. Starting from these two authors and based in the culinary system notion, this paper quests to situate the role of indigenous groups in the brazilian sweets formation and numbers the possibles causes to invisibility of sweets by indigenous at the culinary formation process.RESUMO: Nas obras de Gilberto Freyre e Câmara Cascudo, que tanto influenciaram a literatura sobre a alimentação brasileira, a participação dos grupos indígenas no processo de formação da doçaria nacional é negligenciada. Contudo, é possível encontrar nas“entrelinhas” das obras destes dois autores valiosas informações sobre as contribuições indígenas a este processo. A partir destes dois autores e baseado na noção de sistemas culinários, o presente artigo busca situar o papel dos grupos indígenas na formação da doçaria brasileira e elencar as possíveis razões para a invisibilidade da doçaria de origem indígena no processo de formação da culinária nacional.

  12. Patient characteristics associated with hospitalisations for ambulatory care sensitive conditions in Victoria, Australia

    Directory of Open Access Journals (Sweden)

    Ansari Zahid

    2012-12-01

    Full Text Available Abstract Background Ambulatory Care Sensitive Conditions (ACSCs are those for which hospitalisation is thought to be avoidable with the application of preventive care and early disease management, usually delivered in a primary care setting. ACSCs are used extensively as indicators of accessibility and effectiveness of primary health care. We examined the association between patient characteristics and hospitalisation for ACSCs in the adult and paediatric population in Victoria, Australia, 2003/04. Methods Hospital admissions data were merged with two area-level socioeconomic indexes: Index of Socio-Economic Disadvantage (IRSED and Accessibility/Remoteness Index of Australia (ARIA. Univariate and multiple logistic regressions were performed for both adult (age 18+ years and paediatric (age Results Predictors were much more strongly associated with ACSCs admissions compared to non-ACSCs admissions in the adult group than for the paediatric group with the exception of rurality. Significant adjusted ORs in the adult group were 1.06, 1.15, 1.13, 1.06 and 1.11 for sex, rurality, age, IRSED and ARIA variables, and 1.34, 1.04 and 1.09 in the paediatric group for rurality, IRSED and ARIA, respectively. Conclusions Disadvantaged paediatric and adult population experience more need of hospital care for ACSCs. Access barriers to primary care are plausible causes for the observed disparities. Understanding the characteristics of individuals experiencing access barriers to primary care will be useful for developing targeted interventions meeting the unique ambulatory needs of the population.

  13. Mart Laar - visionäärina kuulsam välismaal / Kertu Ruus

    Index Scriptorium Estoniae

    Ruus, Kertu, 1977-

    2005-01-01

    Maailmas on kümneid riike, kes imetlevad meie endise peaministri Mart Laari reforme Eestis. Kommenteerivad Margaret Thatcher, Alfredo Arias-King ja Tiit Vähi. Vt. samas: Väljavõtteid Mart Laari kohta ajakirjandusest; Laia haardega tegutseja: Liikmelisus

  14. Enfrentar a Reagan y a la Contra: los intelectuales, opinión pública costarricense y la discusión por la paz en Centroamérica (1986-1987

    Directory of Open Access Journals (Sweden)

    David Díaz Arias

    2016-01-01

    Full Text Available Este artículo explora la construcción de una opinión pública en Costa Rica acerca de la guerra en Nicaragua entre los sandinistas y la Contra en 1986-1987 y sobre la política internacional de Costa Rica frente a ese conflicto y frente a los propósitos de expansión de la guerra del presidente estadounidense Ronald Reagan. Se revisan las opiniones emitidas por varios intelectuales costarricenses acerca del plan de paz de Óscar Arias y la construcción que hicieron de su imagen entre 1986 y 1987. Queda en evidencia que, en su afán de producir un total apoyo al plan de paz, los intelectuales costarricenses promovieron acríticamente a Arias como un héroe nacional, regional y casi mundial.

  15. Talvehooaeg Tallinnas pakub palju vene rokki

    Index Scriptorium Estoniae

    2008-01-01

    Kontsertidest: ansambel B-2 koos Läti sümfooniaorkestriga 7. märtsil 2009. a. Tallinna linnahallis, Gorky Park 7. märtsil Biker's Rock Clubis, Mumy Troll 19. veebr. klubis Parlament, Aria 3. apr. Rock Cafés

  16. Rupture dynamics and ground motions from earthquakes in 2-D heterogeneous media

    KAUST Repository

    Bydlon, Samuel A.; Dunham, Eric M.

    2015-01-01

    become appreciable beyond ∼3km from the fault. Near-fault scattering extends the duration of incoherent, high-frequency ground motions and, at least in our 2-D simulations, elevates root-mean-square accelerations (i.e., Arias intensity) with negligible

  17. SU-E-CAMPUS-T-01: Automation of the Winston-Lutz Test for Stereotactic Radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Litzenberg, D; Irrer, J; Kessler, M; Lam, K [University of Michigan, Ann Arbor, MI (United States); Keranen, W [Varian Medical Systems, Inc., Palo Alto, CA (United States)

    2014-06-15

    Purpose: To optimize clinical efficiency and shorten patient wait time by minimizing the time and effort required to perform the Winston-Lutz test before stereotactic radiosurgery (SRS) through automation of the delivery, analysis, and documentation of results. Methods: The radiation fields of the Winston-Lutz (WL) test were created in a “machine-QA patient” saved in ARIA for use before SRS cases. Images of the BRW target ball placed at mechanical isocenter are captured with the portal imager for each of four, 2cm×2cm, MLC-shaped beams. When the WL plan is delivered and closed, this event is detected by in-house software called EventNet which automates subsequent processes with the aid of the ARIA web services. Images are automatically retrieved from the ARIA database and analyzed to determine the offset of the target ball from radiation isocenter. The results are posted to a website and a composite summary image of the results is pushed back into ImageBrowser for review and authenticated documentation. Results: The total time to perform the test was reduced from 20-25 minutes to less than 4 minutes. The results were found to be more accurate and consistent than the previous method which used radiochromic film. The images were also analyzed with DoseLab for comparison. The difference between the film and automated WL results in the X and Y direction and the radius were (−0.17 +/− 0.28) mm, (0.21 +/− 0.20) mm and (−0.14 +/− 0.27) mm, respectively. The difference between the DoseLab and automated WL results were (−0.05 +/− 0.06) mm, (−0.01 +/− 0.02) mm and (0.01 +/− 0.07) mm, respectively. Conclusions: This process reduced patient wait times by 15–20 minutes making the treatment machine available to treat another patient. Accuracy and consistency of results were improved over the previous method and were comparable to other commercial solutions. Access to the ARIA web services is made possible through an Eclipse co-development agreement

  18. La inteligencia artificial como tecnolog??a de mejora humana y el debate sobre sus aplicaciones de doble uso

    OpenAIRE

    Moreno Mu??oz, Miguel

    2016-01-01

    La comunicaci??n fue presentada en la Mesa 1 (Aula 19, viernes 15 de enero, 11:30-13:00 hs): Bio??tica, gobernanza y actuales posibilidades biotecnol??gicas de mejora humana. Coordinadores: Francisco Lara, David Rodr??guez-Arias y Carissa V??liz.

  19. Value Creation from Internationalization of Sugar Cane by-products: a multi-stakeholder view of artisanal cachaça production

    Directory of Open Access Journals (Sweden)

    Daiane Mulling Neutzling

    2015-09-01

    Full Text Available Objective – The aim of this paper was to identify the strategies developed for internationalization in order to create value in the artisanal cachaça sector of Brazil. Design/methodology/approach – A multiple-case study was applied in two artisanal cachaçarias. we carried out in-depth, semi-structured interviews with different stakeholders involved in supporting internationalization of these companies. To select the stakeholders we used snowball sampling. The content of the interviews was categorized and analysed according to accepted theory. Findings – Our study provides an overview of the organization and structure of the cachaçarias and reveals how internationalization is adding value to this network from a multi-stakeholder view. The support of the multi-stakeholder network is in an early stage, but it offers a promising future, since there is a consumer market being developed. Political power is needed to regulate the industry. Practical implications – Business internationalization of the handmade cachaça sector is a challenge, as most companies are small and do not have adequate financial resources or proper knowledge regarding international markets. Regulatory stakeholders support the cachaçarias in standardizing production and developing international strategies. The results can help to better understand the importance of collaboration embedded in stakeholder network relationships. Originality/value – Empirical research on internationalization in developing countries, especially in small and mediums sized firms is still very limited. We have shown that companies can benefit from specific organization structures when developing relationships within multi-stakeholder networks.

  20. Field Surveys to Identify Biocontrol Agents of Hydrilla verticillata from June - September 2012

    Science.gov (United States)

    2015-07-01

    taxonomists for full identification. Chironomid larvae damaging tips and emerging adults were collected from hydrilla at Chetian Town, Lizui Town, and...R. S. Arias, B. E. Scheffler, S. O. Duke, M. Netherland, F. E. Dayan. 2004. Somatic mutation-mediated evolution of herbicide resistance in the

  1. diet with l-asd d,l-methionine on the growth of yiudfish clar

    African Journals Online (AJOL)

    BSN

    \\·oL9 Vo. I (1998). 9. EFFECT OF SUPPLEMENTATION OF SOYABEA~ DIET WITH .... OOp.m. with a lOtal daily ration equal lO 3% of their body weight. ..... protein source in piratical diets of Orechromis 11iloticus and C/arias gariepinus Asian.

  2. Il Raffrescamento per Ventilazione

    DEFF Research Database (Denmark)

    Perino, Marco; Heiselberg, Per Kvols

    2016-01-01

    termicamente e sempre più a tenuta d'aria. Tali misure hanno consentito indubbiamente di ridurre la domanda energetica per il riscaldamento invernale, ma hanno determinato delle crescenti problematiche di surriscaldamento dell'ambiente interno. Molti degli edifici ad alta efficienza energeti-ca di nuova...

  3. In the Aftermath of War: US Support for Reconstruction and Nation-Building in Panama Following Just Cause

    Science.gov (United States)

    1993-08-01

    Politics, 3d ed. (New York : University Press of America, 1988); Richard Shultz, "Can Democratic Governments Use Military Force in the War...Porras, Arnulfo Arias Madrid (Panama: Litho- Impresora , S. A., 1980); Ropp, Panamanian Politics ; and Milled . 10 . Nordlinger. While there is a rich

  4. "Testimonio" as Praxis for a Reimagined Journalism Model and Pedagogy

    Science.gov (United States)

    Aleman, Sonya M.

    2012-01-01

    The differences between journalism and "testimonio" are stark: One is premised on verifiable truths (Mindich, 1998), while the other treats truth as fractional, relative, subjective, and communal (Arias, 2001; Binford, 2001; Delgado Bernal, 2006a; Latina Feminist Group, 2001). Nonetheless, Chicana/o journalism students developing a…

  5. Mechanism(s) of Electricity Production by Shewanella and other Microbes: Understanding and Optimization

    Science.gov (United States)

    2013-08-23

    on to fruitful research careers because of the experience. Collaborations with other Institutions: 1. University of New Mexico – Atanassov’s MURI...Y., A. Obraztsova, G. Rosen, J. Leather , K.G. Scheckel, K.H. Nealson, and Y.M. Arias-Thode. 2011. Marine microbial community response to inorganic

  6. INDUCTION OF ARTIFICIAL MEIOTIC GY~OGENESIS WITH ...

    African Journals Online (AJOL)

    BSN

    INDUCTION OF ARTIFICIAL MEIOTIC GY~OGENESIS WITH. ULTRAVIOLET RAYS IN THE AFRICA:" CATFISH, CI.ARIAS. ANGUILLARIS. ABSTRACT. P.O. ALUKO. National Institute for Freshwater Fisheries. Research, P.M.B. 6006, New Bussa. Artificial gynogenesis was induced in Clarias a11gw aris ) fenilizing the eggs ...

  7. Ask Alice: an Artificial Retrieval of Information Agent

    NARCIS (Netherlands)

    Valstar, M.; Baur, T.; Cafaro, A.; Ghitulescu, A.; Potard, B.; Wagner, J.; Andre, E.; Durieu, L.; Aylett, M.; Dermouche, P.; Pelachaud, C.; Coutinho, E.; Schuller, B.; Zhang, Yue; Heylen, Dirk K.J.; Theune, Mariet; van Waterschoot, Jelte Barachia

    2016-01-01

    We present a demonstration of the ARIA framework, a modular approach for rapid development of virtual humans for information retrieval that have linguistic, emotional, and social skills and a strong personality. We demonstrate the capabilities of our framework in a scenario where a popular book from

  8. Creating an International Network of Democracy Builders | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Creating an International Network of Democracy Builders. The Centre for the Study of Democracy (CSD) at Queen's University will conduct three case studies on democratic transition in Liberia, Costa Rica and Palestine, partnering with the Sua Foundation, the Arias Foundation and the Arab Thought Forum, respectively.

  9. Gioco e Avanguardia: non siamo tutti un po’ Dada?

    DEFF Research Database (Denmark)

    Prager, Phillip

    2015-01-01

    Il Dadaismo, movimento artistico che si affermò alla fine del 1910 e nei primi anni Venti, sfidò le tradizionali nozioni di arte ed estetica. I dadaisti, per esempio, gettavano ritagli di carta colorata in aria per comporre ipotetici collage, eseguivano poesie prive di valore semantico e creavano...

  10. Cantada al Santísimo con violines. Llegue la suerte mía

    OpenAIRE

    Morales

    2010-01-01

    Tabla de contenido: 1. Violín primero; 2. Violín segundo; 3. Acompañamiento; 4. Recitado y aria.Folio 2. Acompañamiento.Folio 3. Violín primero.Folio 4. Violín segundo.Folio 5. Cantada al Santísimo.Folio 5-7. Letra.

  11. Validation of the MASK-rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control

    NARCIS (Netherlands)

    Caimmi, D.; Baiz, N.; Tanno, L. K.; Demoly, P.; Arnavielhe, S.; Murray, R.; Bedbrook, A.; Bergmann, K. C.; de Vries, G.; Fokkens, W. J.; Fonseca, J.; Haahtela, T.; Keil, T.; Kuna, P.; Mullol, J.; Papadopoulos, N.; Passalacqua, G.; Samolinski, B.; Tomazic, P. V.; Valiulis, A.; van Eerd, M.; Wickman, M.; Annesi-Maesano, I.; Bousquet, J.; Agache, I.; Angles, R.; Anto, J. M.; Asayag, E.; Bacci, E.; Bachert, C.; Baroni, I.; Barreto, B. A.; Bedolla-Barajas, M.; Bertorello, L.; Bewick, M.; Bieber, T.; Birov, S.; Bindslev-Jensen, C.; Blua, A.; Bochenska Marciniak, M.; Bogus-Buczynska, I.; Bosnic-Ancevich, S.; Bosse, I.; Bourret, R.; Bucca, C.; Buonaiuto, R.; Caiazza, D.; Caillot, D.; Caimmi, D. P.; Camargos, P.; Canfora, G.; Cardona, V.; Carriazo, A. M.; Cartier, C.; Castellano, G.; Chavannes, N. H.; Ciaravolo, M. M.; Cingi, C.; Ciceran, A.; Colas, L.; Colgan, E.; Coll, J.; Conforti, D.; Correira de Sousa, J.; Cortés-Grimaldo, R. M.; Corti, F.; Costa, E.; Courbis, A. L.; Cruz, A.; Custovic, A.; Dario, C.; da Silva, M.; Dauvilliers, Y.; de Blay, F.; Dedeu, T.; de Feo, G.; de Martino, B.; Di Capua, S.; Di Carluccio, N.; Dray, G.; Dubakiene, R.; Eller, E.; Emuzyte, R.; Espinoza-Contreras, J. M.; Estrada-Cardona, A.; Farrell, J.; Ferrero, J.; Fontaine, J. F.; Forti, S.; Gálvez-Romero, J. L.; Garcia Cruz, M. H.; García-Cobas, C. I.; Gemicioğlu, B.; Gerth van Wijck, R.; Guidacci, M.; Gómez-Vera, J.; Guldemond, N. A.; Gutter, Z.; Hajjam, J.; Hellings, P.; Hernández-Velázquez, L.; Illario, M.; Ivancevich, J. C.; Jares, E.; Joos, G.; Just, J.; Kalayci, O.; Kalyoncu, A. F.; Karjalainen, J.; Khaltaev, N.; Klimek, L.; Kull, I.; Kuna, T. P.; Kvedariene, V.; Kolek, V.; Krzych-Fałta, E.; Kupczyk, M.; Lacwik, P.; Larenas-Linnemann, D.; Laune, D.; Lauri, D.; Lavrut, J.; Lessa, M.; Levato, G.; Lewis, L.; Lieten, I.; Lipiec, A.; Louis, R.; Luna-Pech, J. A.; Magnan, A.; Malva, J.; Maspero, J. F.; Mayora, O.; Medina-Ávalos, M. A.; Melen, E.; Menditto, E.; Millot-Keurinck, J.; Moda, G.; Morais-Almeida, M.; Mösges, R.; Mota-Pinto, A.; Muraro, A.; Noguès, M.; Nalin, M.; Napoli, L.; Neffen, H.; O'Hehir, R.; Olivé Elias, M.; Onorato, G.; Palkonen, S.; Pépin, J. L.; Pereira, A. M.; Persico, M.; Pfaar, O.; Pozzi, A. C.; Prokopakis, E. P.; Raciborski, F.; Rizzo, J. A.; Robalo-Cordeiro, C.; Rodríguez-González, M.; Rolla, G.; Roller-Wirnsberger, R. E.; Romano, A.; Romano, M.; Salimäki, J.; Serpa, F. S.; Shamai, S.; Sierra, M.; Sova, M.; Sorlini, M.; Stellato, C.; Stelmach, R.; Strandberg, T.; Stroetman, V.; Stukas, R.; Szylling, A.; Tibaldi, V.; Todo-Bom, A.; Toppila-Salmi, S.; Tomazic, P.; Trama, U.; Triggiani, M.; Valero, A.; Valovirta, E.; Vasankari, T.; Vatrella, A.; Ventura, M. T.; Verissimo, M. T.; Viart, F.; Williams, S.; Wagenmann, M.; Wanscher, C.; Westman, M.; Young, I.; Yorgancioglu, A.; Zernotti, E.; Zurbierber, T.; Zurkuhlen, A.; de Oliviera, B.; Senn, A.

    2017-01-01

    Background: Visual Analogue Scale (VAS) is a validated tool to assess control in allergic rhinitis patients. Objective: The aim of this study was to validate the use of VAS in the MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) app (Allergy Diary) on smartphones screens to

  12. The influence of α-amylase supplementation, γ-irradiation (60Co) as well as long time of storage of wheat grain on flour technological properties

    International Nuclear Information System (INIS)

    Warchalewski, J.R.

    1989-01-01

    The varieties of winter wheat, Aria and Beta, were studied. The Aria variety was stored for the period of four years. The part of wheat grain from Beta variety was irradiated with γ rays ( 60 Co). In extracts from wheat kernels and flour protein content, total α- and β-amylolytic activity as well as α-amylolytic activity were determined, α-amylases of native and fungal origin were added to the flour obtained from samples of stored wheat kernels (Aria), irradiated and non-irradiated (Beta). Consequently native α-amylase activity of flour increased by 25% and 50%, respectively. Extensive technological estimation of grain and flour with amylase supplements was carried out. The study included: sedimentation analysis, falling number test, milling experiment, farinogram and extensogram analyses, measurement of the degree of damaged starch and flour colour, as well as baking experiment. The obtained experimental loaves of bread were tested for their ability to remain fresh. It was found out that the stored grain flour was characterized by the highest α-amylolytic activity and the lowest falling number value, whereas the irradiated grain flour showed the highest degree of starch damage and water absorption. When α-amylase supplementation to doughs was not accompanied by either irradiation or storage of grain, it definitely changed their physical properties for the worse. The negative influence of native α-amylases appeared to be less significant than that of fungal α-amylases. The positive influence of α-amylase supplementations, especially of those increasing by 25% the native α-amylolytic activity of flour on volume, and freshness of loaves of bread was observed. (author)

  13. El amor en personas con discapacidad intelectual y su repercusión en el bienestar emocional, de Morentin, R. et al.

    Directory of Open Access Journals (Sweden)

    SIIS Centro de Documentación y Estudios

    2013-07-01

    Full Text Available Reseña de la obra 'El amor en personas con discapacidad intelectual y su repercusión en el bienestar emocional' (2012 de Raquel Morentin Gutiérrez, Benito Arias Martínez, José Manuel Rodríguez Mayoral y Miguel Ángel Verdugo Alonso.

  14. CpG-STAT3siRNA for Castration-Resistant Prostate Cancer Therapy

    Science.gov (United States)

    2015-12-01

    preliminary studies (Supplementary Fig. S2). Then selected myeloid cell populations were isolated using high- speed cell sorting using FACS-Aria (BD...experimental conditions, we analyzed IFNg and granzyme B production by CD8þ T cells. Both IFNg (Fig. 5G ) and granzyme B (Fig. 5H) expression levels were

  15. Bassani – Brentner – Villicus: hudební repertoár dvou rukopisných sborníků z piaristického kláštera v Podolínci

    Czech Academy of Sciences Publication Activity Database

    Kapsa, Václav

    3 /29/, č. 2 (2012), s. 195-215 ISSN 1338-2594 R&D Projects: GA ČR GPP409/12/P953; GA MŠk(CZ) MEB0810155 Keywords : baroque music * solo motet * arias * cantatas * musical sources * Jan Josef Ignác Brentner * Giovanni Battista Bassani Subject RIV: AL - Art, Architecture, Cultural Heritage

  16. Higher holonomies: comparing two constructions

    DEFF Research Database (Denmark)

    Schaetz, Florian; Arias Abad, Camilo

    2015-01-01

    , there are the higher holonomies associated with flat superconnections as studied by Igusa [7], Block–Smith [3] and Arias Abad–Schätz [1]. We first explain how by truncating the latter construction one obtains examples of the former. Then we prove that the two-dimensional holonomies provided by the two approaches...

  17. European Scientific Notes. Volume 7, Number 6.

    Science.gov (United States)

    1953-03-15

    b — l o — s 3 T1~~~ :cI i i tics f cr Research In Nu; leer Phva :cs aol Co5mic .t..ys ~~ .. A.’_ ...:.:..s...-~ by ~~~~~~~ aria t~~ r , bI~tge: C. 1

  18. Language Ideology Change over Time: Lessons for Language Policy in the U.S. State of Arizona and Beyond

    Science.gov (United States)

    Fitzsimmons-Doolan, Shannon

    2018-01-01

    In the U.S. state of Arizona, language minority students who are English learners attend schools governed by a restrictive medium of instruction (MOI) language policy (LP). Educators and educational researchers widely agree that effective reforms of this policy are urgently needed (e.g., Arias & Faltis, 2012; Lawton, 2012; Lillie, 2016).…

  19. Comparing humans and deep learning performance for grading AMD: A study in using universal deep features and transfer learning for automated AMD analysis.

    Science.gov (United States)

    Burlina, Philippe; Pacheco, Katia D; Joshi, Neil; Freund, David E; Bressler, Neil M

    2017-03-01

    When left untreated, age-related macular degeneration (AMD) is the leading cause of vision loss in people over fifty in the US. Currently it is estimated that about eight million US individuals have the intermediate stage of AMD that is often asymptomatic with regard to visual deficit. These individuals are at high risk for progressing to the advanced stage where the often treatable choroidal neovascular form of AMD can occur. Careful monitoring to detect the onset and prompt treatment of the neovascular form as well as dietary supplementation can reduce the risk of vision loss from AMD, therefore, preferred practice patterns recommend identifying individuals with the intermediate stage in a timely manner. Past automated retinal image analysis (ARIA) methods applied on fundus imagery have relied on engineered and hand-designed visual features. We instead detail the novel application of a machine learning approach using deep learning for the problem of ARIA and AMD analysis. We use transfer learning and universal features derived from deep convolutional neural networks (DCNN). We address clinically relevant 4-class, 3-class, and 2-class AMD severity classification problems. Using 5664 color fundus images from the NIH AREDS dataset and DCNN universal features, we obtain values for accuracy for the (4-, 3-, 2-) class classification problem of (79.4%, 81.5%, 93.4%) for machine vs. (75.8%, 85.0%, 95.2%) for physician grading. This study demonstrates the efficacy of machine grading based on deep universal features/transfer learning when applied to ARIA and is a promising step in providing a pre-screener to identify individuals with intermediate AMD and also as a tool that can facilitate identifying such individuals for clinical studies aimed at developing improved therapies. It also demonstrates comparable performance between computer and physician grading. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. SU-F-T-241: Reduction in Planning Errors Via a Process Control Developed Using the Eclipse Scripting API

    Energy Technology Data Exchange (ETDEWEB)

    Barbee, D; McCarthy, A; Galavis, P; Xu, A [NYU Langone Medical Center, New York, NY (United States)

    2016-06-15

    Purpose: Errors found during initial physics plan checks frequently require replanning and reprinting, resulting decreased departmental efficiency. Additionally, errors may be missed during physics checks, resulting in potential treatment errors or interruption. This work presents a process control created using the Eclipse Scripting API (ESAPI) enabling dosimetrists and physicists to detect potential errors in the Eclipse treatment planning system prior to performing any plan approvals or printing. Methods: Potential failure modes for five categories were generated based on available ESAPI (v11) patient object properties: Images, Contours, Plans, Beams, and Dose. An Eclipse script plugin (PlanCheck) was written in C# to check errors most frequently observed clinically in each of the categories. The PlanCheck algorithms were devised to check technical aspects of plans, such as deliverability (e.g. minimum EDW MUs), in addition to ensuring that policy and procedures relating to planning were being followed. The effect on clinical workflow efficiency was measured by tracking the plan document error rate and plan revision/retirement rates in the Aria database over monthly intervals. Results: The number of potential failure modes the PlanCheck script is currently capable of checking for in the following categories: Images (6), Contours (7), Plans (8), Beams (17), and Dose (4). Prior to implementation of the PlanCheck plugin, the observed error rates in errored plan documents and revised/retired plans in the Aria database was 20% and 22%, respectively. Error rates were seen to decrease gradually over time as adoption of the script improved. Conclusion: A process control created using the Eclipse scripting API enabled plan checks to occur within the planning system, resulting in reduction in error rates and improved efficiency. Future work includes: initiating full FMEA for planning workflow, extending categories to include additional checks outside of ESAPI via Aria

  1. The vocabulary of the 'Lengua de Maynas', Ms. Egerton 2881 of the British Library

    NARCIS (Netherlands)

    Alexander-Bakkerus, A.

    2009-01-01

    El manuscrito Egerton 2881 de la British Library (Londres) data del comienzo del siglo XIX. El autor del manuscrito es anónimo. En los folios 7 y 40 recto se encuentran las siguientes observaciones: folio 7 r. : "Es del vso del V.P. Fr. Eusebio Arias"; folio 40 r. : "Pertenesco al P. Fr. Eusebio

  2. L'isola di Demetra e il destino di Kore nella poesia di Dacia Maraini ...

    African Journals Online (AJOL)

    The present essay deals with Dacia Maraini's early collections of poems: Crudeltà all'aria aperta (1966), Donne mie (1974) e Mangiami pure (1978). The central theme of this critical appraisal of the author's works is the myth of Demeter and Kore and its relevance to the development of the speaking subject. Tradition places ...

  3. Trinidad Reservoir Salvage Archaeology, 1972.

    Science.gov (United States)

    1974-09-30

    Components:. Acer glabrum, Alnus tennuifolia, BlepharoneUron tricholepis, Ceano- thus fendlerif Chamabati aria Millef aim, Festuca arizonica , Holodiscus...southern part), !j. occi- dentalis, Orvzopsis hymeihiodes, Purshia tridentata, Quercus emorvi, _q- gambelii, _q. grisea, _q. undulata, Sporobolus...evergreen trees Dominants: Corkbark fir (Abies lasiocarpa var. arizonica ) Engelmann spruce (Picea engel- mannii) Other Components: Abies lasiocarpa, Acer

  4. South African Journal for Research in Sport, Physical Education and ...

    African Journals Online (AJOL)

    Distances and Shooting Zones as a Function of Mass of Basketball among 9- to 11-Year-Old Male Players · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JL Arias, FM Argudo, JI Alonso, 1-11. A Multi-Stage Integer Programming Approach to Fantasy Team Selection: A Twenty20 ...

  5. UNPUBLISHED TEXTS / INEDITI

    African Journals Online (AJOL)

    User

    l'equilibrio delle idee fraintendimenti disarmonici da cancellare. Melodia argentata. Ho ripreso a cantare questa melodia argentata alle cime più alte e alla triangolare Grivola scivolata a mezz'aria. Mi attrae la leggerezza del fogliame la punta dei pini il verde del prato dall'erba anche azzurra e cresciuta tra i fiori gialli e.

  6. Personajes, ideologías y circunstancias: lo socialdemócrata en Centroamérica

    Directory of Open Access Journals (Sweden)

    Edelberto TORRES RIVAS

    2009-11-01

    Full Text Available RESUMEN: En este ensayo se traza una semblanza de los distintos proyectos políticos y experiencias socialdemócratas en Centroamérica. La evolución crítica de la obra de personajes como Arbenz, Figueres, Ortega y Arias da paso a la conclusión de que la tarea que las fuerzas de izquierda deben acometer en el presente momento es asumir los valores de la solidaridad, de la comunidad, de los que no han satisfecho ninguno de sus problemas, como fundamento de una democracia política que tenga como base una democracia social.ABSTRACT: In this article, the author draw a vision of the different socialdemocracy political projects and experiences in Central America. The work of personages such us Arbenz, Figueres, Ortega and Arias is examinated from a critical point of view. The conclusion for the nineties is that the leftist Central American political forces must assume the values of solidarity, comunity, people who is unsatisfied, in order to join political and social democracy.

  7. Influence of air pollution by compounds of fluorine, sulphur and nitrogen on changes of peroxidase and polyphenol oxidase activity in the leaves of trees and bushes

    Directory of Open Access Journals (Sweden)

    Y. Prysedskyj

    2017-08-01

    pollutants (Sorbus aucuparia L., Fraxinus lanceolata Borkh were characterized by the significant decline in peroxidase and polyphenoloxidase activity, by 18.7–79.1% and 20.5–71.2% respectively, depending on the duration of action of the gases in all variants of the experiment. In species with variable tolerance (Aesculus hippocastanum L., Acer negundo L., Populus simonii Carriere the reaction to the pollutants was ambiguous in nature and depended on the presence of damage. If the leaves of these plants did not show visible damage (necrosis, then activity of the enzymes did not change. When there was damage to leaf laminae this index decreased in relation to control by 17.3–60.1% for peroxidase and 24.7–57.3% for polyphenoloxidase. Significant negative linear correlation was found between activity of antioxidant enzymes and damage to leaves of the investigated plants: the coefficients of correlation were –0.385 between peroxidase activity and damage and –0.130 between polyphenoloxidase activity and damage. The character of changes in peroxidase and polyphenoloxidase activity show that these enzymes play a considerable role in the detoxication of pollutants and that there is a reduction in their influence on metabolic processes of plant organisms.

  8. Dynamics of forest populations in the mountain resort region of the North Caucasus

    Science.gov (United States)

    Chalaya, Elena; Efimenko, Natalia; Slepykh, Olga; Slepykh, Viktor; Povolotskaya, Nina

    2017-04-01

    Prehistoric formula of forest species composition of the resort region Caucasian Mineralnye Vody (RR CMV) in the North Caucasus is 6Q3Cb1Fe [1]. According to it, undisturbed forests of the region consisted of the pedunculate oak (Quercus robur L.) and the durmast (Quercus cerris L.) by 60%, the European hornbeam (Carpinus betulus L.) by 30% and the European ash (Fraxinus excelsior L.) only by 10%. At present the formula of forest composition of the region is 5Fe3Cb2Q, according to it, the rate of oak-groves (the most valuable to resort landscape gardening) has reduced to 20%, and the ash-tree, though the rate of the hornbeam has not changed, increased up to 50%. Forest breeding populations in the RR CMV are referred to natural medical resources as they have high rehabilitation and climate-regulating properties, the change in forest breeding populations influences the conditions of the resort climate-landscape-therapy. The researches conducted in the perfect oak wood of vegetative origin in Beshtaugorsky Forestry Area (BFA) of the RR CMV have shown the reduction of the pedunculate oak in the tree-stand composition during 1984-2014 from 10 to 8 units in the composition: the European ash (1 unit) and the crataegus monogyna (Crataegus monogyna Jacq.), the checker tree (Sorbus torminalis (L.) Crantz), the common pear (Pyrus communis L.) have appeared [2]. The rate of the pedunculate oak decreased from 10 units to 9 in the perfect planting of the pedunculate oak of the artificial origin (Mashuk section of the forestry of BFA of the RR CMV) during 1986-2016. Among accompanying breeds there was the English field maple (Acer campestre L.), the Chinese elm in singular (Ulmus parvifolia Jacq.), the single-seed hawthorn. The reliable regrowth (4C3Fe3Ac+Q+Cm+Pc+Up) in number of 3,9 thousand pieces/hectare defines the perspective of complete replacement of the oak crop in the future on planting with dominance of the hornbeam and the involvement of the ash-tree and the English

  9. Timing of plant phenophases since 1752 in the boreal forest environment

    Science.gov (United States)

    Kubin, Eero; Tolvanen, Anne; Karhu, Jouni; Valkama, Jari

    2016-04-01

    Global warming and climate change will significantly affect on forest environment in northern latitudes. There is the strong evidence that increase of early spring and late autumn temperatures will have impacts on growth and growth cycles. In Finland the Finnish Forest Research Institute (Luke since 2015) established in 1996 National Phenological Network to study changes of phenophases all over the country representing southern, middle and northern boreal forest zones. Continuous detailed scientific monitoring includes eleven forest plant species and it forms an excellent basis to evaluate responses of forest vegetation in respect to climate change. Monitoring is done together with Universities and other Institutes. Prior to the establishment of the Finnish National Phenological Network observations has been made solely based on volunteers since 1752. This citizen-science data is very important to analyze phenophases together with the results of the National Network. The long-term data since 1752 shows e.g. an advancement in the onset of Prunus padus flowering by five days per 100 years and correspondingly three days in the rowan (Sorbus aucuparia). The latest results of the Finnish National Network (1996 - 2014) fits well to this long term trend. In the Finnish National Phenological Network we have monitored phenophases of forest spieces throughout the growth period, focusing on nine forest tree species and two dwarf shrubs. The results can be followed in real time at: http://www.metla.fi/metinfo/fenologia/index-en.htm. We have observed big differences in phenophases between southern and northern boreal zone. Onset of downy birch leafing happens one month later in the north compared with southern boreal zone. Coming into leaf has clearly occurred earlier during the research period since 1996 in the northern boreal zone compared with southern boreal zone. This indicates the response of climate change. The timing of leaf colouring and leaf fall was observed remained

  10. From COBRA to the Seine, August 1944: A Microcosm of the Operational Art

    Science.gov (United States)

    1986-05-09

    while Patto , c,,rducted operational maneuvers in the German rear. Hill 217 was decisive t erra i r. The 2nd SS Piz Div reached almost to St.Hilaire by...with Eberbach as a r-eplacement for- vonr Funick. But the combined effects oif TOTALIZE, stiffening pressure at lortamii aria Patto -n’ 5 cuit north

  11. Synthesis of Chromophores for Nonlinear Optics Applications

    Science.gov (United States)

    2010-03-12

    Investigacion de Quimica Aplicada Blvd. Enrique reyna, No. 140 Saltillo, Coahuila, Mexico 25253 AFOSR FA9550-09-1-0017 12 March 2010...PERFORMING ORGANIZATION REPORT NUMBER CENTRO DE INVESTIGACION EN QUIMICA APLICADA BLVD ENRIQUE REYNA NO 140 SALTILLO 25253 MEXICO...APPLICATIONS Eduardo Arias, Ivana Moggio and Ronald F. Ziolo Centro de Investigacion de Quimica Aplicada Saltillo, Coahuila, Mexico 25253

  12. El mundo del libro: septiembre de 1960

    Directory of Open Access Journals (Sweden)

    Agustín Rodríguez Garavito

    1960-09-01

    Full Text Available -La vida privada de los colombianos / Eduardo Caballero Calderón -Memorias de un músico de Bochalema / José Rozo Contreras -Velásquez / Jorge Santader Arias -Georges Bernanos / Louis Chaigne -Poesía completa / Julio Barrenechea -El chamanismo / Mircea Eliade -Historias médicas / Jaime Mejía y Mejía

  13. Egyptian Journal of Pediatric Allergy and Immunology (The) - Vol 15 ...

    African Journals Online (AJOL)

    ARIA 2016 Executive Summary Integrated care pathways for predictive medicine across the life cycle · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Y.M. El-Gamal, E.M. Hossny, Z.A. El-Sayed, M El-Seify, S.M. Reda, S.S. El-Sayed, I Agache, C Bachert, A Bedbrook, ...

  14. Research

    African Journals Online (AJOL)

    abp

    18 août 2013 ... Apoyo nutricional perioperatorio en pacientes con neoplasia colorrectal. Nutr Hosp. 2010; 25(5):. 797-805. PubMed| Google Scholar. 13. Cid Conde L, Fernández López T, Neira Blanco P, Arias Delgado. J et al. Prevalencia de desnutrición en pacientes con neoplasia digestiva previa cirugía. Nutr Hosp.

  15. Review Of Clinical Features Of Malaria | Onyenekwe | Orient Journal ...

    African Journals Online (AJOL)

    In the early 17th century, the “Peruvian Bark” or Jesuits Powder” was discovered to be of value in the treatment of certain fevers. The tree was later to be named cinchona from which quinine was extracted in 1820. Such fever was known as the agues in England, in Italy as mal'aria and in France as Palludisme due to their ...

  16. UNPUBLISHED TEXTS / INEDITI

    African Journals Online (AJOL)

    User

    È come una fetta di luna. L'nguria che assaggi e che sputi non ti puoi saziare come del mare e dell'aria e dei pini marittimi e di questa quercia alberi dal tronco di sughero che è facile strappare, corteccia che ricresce. Non ti puoi saziare di questo mare verde e profondo luminosa acqua pietre pesci coralli gusci di perle.

  17. Cholesteric Liquid Crystal Glass Platinum Acetylides

    Science.gov (United States)

    2014-06-01

    M. Krein AFRL/RXAP Ronald F. Ziolo, Eduardo Arias, and Ivana Moggio 2Centro de Investigacion en Quimica Aplicada(CIQA) Albert Fratini... Quimica Aplicada(CIQA), Boulevard Enrique Reyna Albert Fratini - Department of Chemistry, University of Dayton Yuriy Garbovskiy and Anatoliy...Force Research Laboratory Materials and Manufacturing Directorate Wright-Patterson Air Force Base, OH 45433-7750 Centro de Investigacion en Quimica

  18. Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA and World Allergy Organization (WAO document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA and Global Allergy and Asthma European Network (GA2LEN

    Directory of Open Access Journals (Sweden)

    F. Braido

    2016-10-01

    Full Text Available Abstract Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD has led INTERASMA (Global Asthma Association and WAO to take a position on the role of the small airways in these diseases. Starting from an extensive literature review, both organizations developed, discussed, and approved the manifesto, which was subsequently approved and endorsed by the chairs of ARIA and GA2LEN. The manifesto describes the evidence gathered to date and defines and proposes issues on small airway involvement and management in asthma and COPD with the aim of challenging assumptions, fostering commitment, and bringing about change. The small airways (defined as those with an internal diameter <2 mm are involved in the pathogenesis of asthma and COPD and are the major determinant of airflow obstruction in these diseases. Various tests are available for the assessment of the small airways, and their results must be integrated to confirm a diagnosis of small airway dysfunction. In asthma and COPD, the small airways play a key role in attempts to achieve disease control and better outcomes. Small-particle inhaled formulations (defined as those that, owing to their size [usually <2 μm], ensure more extensive deposition in the lung periphery than large molecules have proved beneficial in patients with asthma and COPD, especially those in whom small airway involvement is predominant. Functional and biological tools capable of accurately assessing the lung periphery and more intensive use of currently available tools are necessary. In patients with suspected COPD or asthma, small airway involvement must be assessed using currently available tools. In patients with subotpimal disease control and/or functional or biological signs of disease activity, the role of small airway involvement should be assessed and treatment tailored. Therefore, the choice between large- and small-particle inhaled

  19. Application of photo-excitation reaction on titanium oxide thin film for control of wettability; Sanka chitann hakumakujo no hikari reiki hanno no nuresei seigyo eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, T.; Nakajima, A.; Hashimoto, K. [The Univ. of Tokyo, Tokyo (Japan); Takada, Y. [Kyushu Univ., Fukuoka (Japan)

    2000-03-31

    It is clarified that the photo-excitation hydrophilic reaction increasing wettability remarkably is induced by changing surface structure of titanium oxide radiated light. There are already many examples being in practical use of coating products applied hydrophilic reaction of titanium oxide surface such as drip-proof side millers for automobiles, self-cleaning building materials, and the like. When surface of titanium oxide having high activities for oxidisation and decomposition is coated organic materials and radiated light, wettability of surface changes as organic materials are decomposed. If it is possible to change wettability shaping pattern drastically by radiating light, the possibility of application for printing materials will be developed. After increasing contact angle by coating water and oil repellent on the titanium oxide thin film, images can be shaped by radiating light into pattern for changing surface of titanium oxide to be ultra hydrophilicity as decomposition of repellent. At that time, contact angle is 150 degree in water, 80 degree in oil, for not radiated aria, and is 0 degree in water and oil for radiated aria. Application for control technology of wettability keeps possibility of broader development to itself, not staying ability of self-cleaning and drip-proof. (NEDO)

  20. Total centralisation and optimisation of an oncology management suite via Citrix®

    International Nuclear Information System (INIS)

    James, C; Frantzis, J; Fenton, P; Ripps, L

    2014-01-01

    The management of patient information and treatment planning is traditionally an intra-departmental requirement of a radiation oncology service. Epworth Radiation Oncology systems must support the transient nature of Visiting Medical Officers (VMOs). This unique work practice created challenges when implementing the vision of a completely paperless solution that allows for a responsive and efficient service delivery. ARIA ® and Eclipse TM (Varian Medical Systems, Palo Alto, CA, USA) have been deployed across four dedicated Citrix ® (Citrix Systems, Santa Clara, CA, USA) servers allowing VMOs to access these applications remotely. A range of paperless solutions were developed within ARIA ® to facilitate clinical and organisational management whilst optimising efficient work practices. The IT infrastructure and paperless workflow has enabled VMOs to securely access the Varian TM (Varian Medical Systems, Palo Alto, CA, USA) oncology software and experience full functionality from any location on multiple devices. This has enhanced access to patient information and improved the responsiveness of the service. Epworth HealthCare has developed a unique solution to enable remote access to a centralised oncology management suite, while maintaining a secure and paperless working environment.

  1. Book Reviews • • Boekbesprekings

    African Journals Online (AJOL)

    Book Reviews •. • Boekbesprekings. BLOOD DISEASES. Arias ot Haematology. 3rd ed. By G. A. McDonald, M.D.. (Aberd.), M.RC.P. (Glasg.), M.RC. Path., T. C. Dodds,. F.I.M.L.T., F.I.I.P.. F.R.P.S. and B. Cruickshank, ... tumours of lymphoid tissues, consisting of pictures of lymph node histology correlated with the blood and ...

  2. TWSTFT Data Treatment for UTC Time Transfer

    Science.gov (United States)

    2009-11-01

    BUREAU INTERNATIONAL DES POIDS ET MESURES ORGANISATION INTERGOUVERNEMENTALE DE LA CONVENTION DU METRE...in [UTC-UTC(k)],” Metrologia , 43, 278-286. [4] BIPM Circular T 244, Section 6, May 2008, http://www.bipm.org [5] D. Piester, A. Bauch, L... Metrologia , 45, 185-198. [6] F. Arias, Z. Jiang, G. Petit, and W. Lewandowski, 2005, “BIPM Comparison of Time Transfer Techniques,” in Proceedings

  3. [How did the castratos sing? Historical observations].

    Science.gov (United States)

    von Deuster, Christian

    2006-01-01

    Historical observations In Church music from the early beginnings to the 19th century, women were not allowed to sing, because of a wrongly interpreted quote of the Apostle Paul. Paul had ordered women to keep silence in ecclesia, it means: in the community and in the congregation, but he himself never mentioned a ban on singing in church. The castratos gradually replaced the men singing falsetto due to the latter's weaker singing performance from the 17th century onwards. They originated mostly from simple social backgrounds. Many poor families in Italy in the 17th and 18th centuries had up to 15 children and there was far too little work for the population. Some castratos were the stars of the opera. But as human beings they were discriminated. The castration took place mostly between the 7th and 12th years of their lives and many died as a result of the operation. The singing-lessons thereafter lasted 5-6 years. In the 18th century, the most famous castrato was Carlo Broschi, named Farinelli (1705-1782). Numerous arias sung by him are still in existence as scores, some are high quality concert pieces. There are modem versions on CD sung by a counter-tenor or a mezzo-soprano as soloists. Farinelli was able, during a visit to Spain, to improve with his singing the mood of two severely depressive kings. In the late 18th and in the 19th century, the castratos were increasingly replaced by tenors and women singers. The only historical sound recordings were sung by one of the last castratos, Alessandro Moreschi (1858-1922). The recordings were made in 1902 and 1904 in the Vatican. The arias are in the style of the end of the 19th century and contain no longer anything of the bravura arias so admired by the audiences in the 18th century. Since the end of World War II, the high male voices have experienced a renaissance.

  4. Monitoring Subsidence in California with InSAR

    Science.gov (United States)

    Farr, T. G.; Jones, C. E.; Liu, Z.; Neff, K. L.; Gurrola, E. M.; Manipon, G.

    2016-12-01

    Subsidence caused by groundwater pumping in the rich agricultural area of California's Central Valley has been a problem for decades. Over the last few years, interferometric synthetic aperture radar (InSAR) observations from satellite and aircraft platforms have been used to produce maps of subsidence with cm accuracy. We are continuing work reported previously, using ESA's Sentinel-1 to extend our maps of subsidence in time and space, in order to eventually cover all of California. The amount of data to be processed has expanded exponentially in the course of our work and we are now transitioning to the use of the ARIA project at JPL to produce the time series. ARIA processing employs large Amazon cloud instances to process single or multiple frames each, scaling from one to many (20+) instances working in parallel to meet the demand (700 GB InSAR products within 3 hours). The data are stored in Amazon long-term storage and an http view of the products are available for users of the ARIA system to download the products. Higher resolution InSAR data were also acquired along the California Aqueduct by the NASA UAVSAR from 2013 - 2016. Using multiple scenes acquired by these systems, we are able to produce time series of subsidence at selected locations and transects showing how subsidence varies both spatially and temporally. The maps show that subsidence is continuing in areas with a history of subsidence and that the rates and areas affected have increased due to increased groundwater extraction during the extended western US drought. Our maps also identify and quantify new, localized areas of accelerated subsidence. The California Department of Water Resources (DWR) funded this work to provide the background and an update on subsidence in the Central Valley to support future policy. Geographic Information System (GIS) files are being furnished to DWR for further analysis of the 4 dimensional subsidence time-series maps. Part of this work was carried out at the

  5. “I am active”: effects of a program to promote active aging

    OpenAIRE

    Mendoza-Ruvalcaba NM; Arias-Merino ED

    2015-01-01

    Neyda Ma Mendoza-Ruvalcaba,1 Elva Dolores Arias-Merino2 1Health Sciences Department, University of Guadalajara, University Center of Tonala Guadalajara, Jalisco, Mexico; 2Public Health Department, University of Guadalajara, University Center of Health Sciences, Guadalajara, Jalisco, Mexico Background: Active aging involves a general lifestyle strategy that allows preservation of both physical and mental health during the aging process. “I am Active” is a program designed...

  6. Latin America Report No. 2532

    Science.gov (United States)

    1982-07-06

    Trimarco himself who put forward Nicolaides’ name, according to military sources. Nicolaides’ father was bom in Greece and his mother in Cordoba...telephone companies, and the water works, as well as other terrorist acts aimed at social clubs, embassies, urban transportation, military hospital centers...34), Jesus Maria Pesca Garcia (alias "Chucho"), Nelson Ortiz Ovalle, Wilson Ramirez Hurtado, Jairo Arias Perez, Ricardo Londono, Elvira Reyes de

  7. The terebinth population (Pistacia mutica Fisсh. & C.A. Mey. in the Besh-Tash valley (South-East Crimea

    Directory of Open Access Journals (Sweden)

    Viktoria Ju. Letukhova

    2016-08-01

    Full Text Available A comprehensive work on the study of rare and protected wood plants on the territory of the Besh-Tash valley (South-East Crimea was carried out on the instructions of Karadag Nature Reserve administration in 2013. The Besh-Tash valley (approximate area of 15 hectares is wedged in the territory of the Karadag reserve from the south-west side, but it is not included in its structure. This article describes the material on distribution, abundance, population structure of terebinth (Pistacia mutica in this area. P. mutica is a Mediterranean relict species of the Tertiary period, included in the Red Books of Russia, Crimea and Ukraine. Terebinth creates rare relict plant communities (formation P. mutica listed in the Green Book of Ukraine. In the study area we counted all P. mutica specimens. We determined their taxation parameters, as well as characterized their locality. Based on the literature and our own research age-state classes of P. mutica were characterized for the studied population. As a result, we registered a total number of 3086 specimens of P. mutica: immature (im – 1259 (40.8%, virginal (v – 1054 (34.2%, young generative (g1 – 341 (11.0%, middle-age generative (g2 – 372 (12.0%, mature generative (g3 – 60 (2.0% plants. Senile plants have not been found out. So the age spectrum of the population is normal, not complete (without senile individuals, left-sided with predominance of immature plants. The population density is 206 specimens/ha. In the Besh-Tash valley P. mutica forms its own dense thickets or it is the component of hemixerophytical oak forests with Quercus pubescens, Juniperus deltoides, rarer Cornus mas, Sorbus torminalis. It also grows in shrub communities with Pyrus elaeagrifolia, Paliurus spina-christi, Prunus spinosa, Rosa corymbifera, Cotoneaster tauricus, Crataegus species, rarer Cotinus coggygria, Clematis vitalba. The distribution of the terebinth tree by elevation above sea level is analyzed. The great

  8. Analyzing spatial variability of soil properties in the urban park before and after reconstruction to support decision-making in landscaping

    Science.gov (United States)

    Romzaikina, Olga; Vasenev, Viacheslav; Khakimova, Rita

    2017-04-01

    assessment were processed using QGIS2.4 and the maps of the vegetation condition were created. High spatial variability was shown for observed soil properties with the highest variance reported for nutrient concentrations. High heterogeneity in P2O5 and K2O was obtained both in topsoil and subsoil, before and after reconstruction. We showed that average concentrations of P2O5 and K2O were correspondingly above and below legal threshold taken for the Moscow city. In result of the reconstruction the pH has changed from slightly acid and acidic to neutral and slightly alkaline. The topsoil SOC content has increased in the result of reconstruction but still was below threshold, recommended by municipal regulations. The potassium content and acidity were the main factors, influencing the vegetation condition. The 'weakened' condition of wood vegetation was reported with the lowest values obtained for the Pinus sylvestris, Thuja occidentals and, Sorbus aucuparia. References have developed for planting vegetation. The spatial heterogeneity and high dynamics of urban soils constraints the quantitative assessment of their properties and functions and the use of this information in landscaping. The successful experience of digital soil mapping techniques in urban park allowed solving this problem and highlighted the importance of soil data for creating urban green infrastructure.

  9. Morphological and physico-biochemical characterization of various tomato cultivars in a simplified soilless media

    Directory of Open Access Journals (Sweden)

    Mahboob Ahmad Khan

    2017-12-01

    Full Text Available This study aimed to investigate nine commercial cultivars of tomato, in order to identify the most suitable cultivar in terms of morphological (plant height, fruit size, fruit weight and total yield and physico-biochemical (color, firmness, total soluble solid, titratable acidity, ascorbic acid, total sugar, reducing and non-reducing sugar, β-carotene and lycopene attributes. Plants were cultured hydroponically in the greenhouse. Results revealed that the morphological attributes of Beefsteak Group (BG of tomatoes was significantly better than that of Cherry Group (CG. In addition, CG has higher concentration of biochemical attributes, mainly β-carotene, sugars, total soluble solids (TSS and ascorbic acid contents. Within CG, cv. Aria was found to be the best for higher sugar contents, β-carotene and ascorbic acid contents; while, TSS was higher in the cv. Claree. Similarly in BG, cv. Sahel had the highest value of lycopene, β-carotene, TSS; whereas, lowest sugar contents were found in cv. Dirk. As far as firmness is concerned, cv. Naram (BG was found to be more firm, than cv. Aria (CG. The highest total yield was recorded for cv. Vernal; in BG and in cv. Claree for CG, depicting that BG had significantly higher total yield, compared with CG.

  10. Diffusione molecolare neLl' alta atmosfera

    Directory of Open Access Journals (Sweden)

    C. ARDUINI

    1963-06-01

    Full Text Available Le perturbazioni indotte nell'alta atmosfera dall'emissione,
    a mezzo di razzi sonda, di nubi di vapori estranei sono un utile
    mezzo per lo studio simultaneo di alcune caratteristiche fisiche e dinamiche
    degli alti strati.
    La presente relazione illustra in breve i principi di alcune tecniche
    per la misura del coefficiente di diffusione binaria tra l'aria e il vapore
    della nube artificiale.

  11. Latin America Report.

    Science.gov (United States)

    1985-07-22

    Endorsed 51 - b - COSTA RICA Candidates on Administration of Unemployment Benefits (RUMBO CENTROAMERICANO , 6-12 Jun 85) =>l PVP Explains...Jose RUMBO CENTROAMERICANO in Spanish 6-12 Jun 85 p XII the benefits for workers should be administered.’ Dr Oscar Arias: I view the plan’s intent...EXCELSIOR in Spanish 26 May 85 pp 1-A, 16-A [Article by correspondents Alfredo Cordova and Porfirio Diaz] Migration, except authorization for Migrants

  12. MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis)

    DEFF Research Database (Denmark)

    Bousquet, J; Schunemann, H J; Fonseca, J

    2015-01-01

    Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patien...

  13. Una vida atormentada y contradictoria: Eduardo Arias Suárez

    Directory of Open Access Journals (Sweden)

    Adel López Gómez

    1965-07-01

    Full Text Available El señor Constantino, personaje central, casi único de Bajo la luna negra, dice en uno de sus frecuentes desvaríos: "Entonces yo volví a ser yo mismo, cuando tenía. solo veinte añios. Hijo de la tierra ardiente que me tostaba la cara y me atropellaba la sangre en las arterias; cazador de jaguares en las montañas del Quindío; nadador intrépido en las aguas del Magdalena; domador de caballos y de mujeres; cantador de bambucos y as del trago, de la baraja y del cuchillo. Yo tenía mucho de la selva en las venas, y mi tierra es abrupta y áspera, con rotundidacles de abismo y de montaña".

  14. Advanced Rapid Imaging & Analysis for Monitoring Hazards (ARIA-MH) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop a service-oriented hazard/disaster monitoring data system enabling both science and decision-support communities to monitor ground motion in areas of...

  15. A REVIEW ON BIOMASS DENSIFICATION TECHNOLOGIE FOR ENERGY APPLICATION

    Energy Technology Data Exchange (ETDEWEB)

    JAYA SHANKAR TUMULURU; CHRISTOPHER T. WRIGHT

    2010-08-01

    The world is currently facing challenges to reduce the dependence on fossil fuels and to achieve a sustainable renewable supply. Renewable energies represent a diversity of energy sources that can help to maintain the equilibrium of different ecosystems. Among the various sources of renewable energy, biomass is finding more uses as it is considered carbon neutral since the carbondioxide released during its use is already part of the carbon cycle (Arias et al., 2008). Increasing the utilization of biomass for energy can help to reduce the negative CO2 impact on the environment and help to meet the targets established in the Kyoto Protocol (UN, 1998). Energy from biomass can be produced from different processes like thermochemical (combustion, gasification, and pyrolysis), biological (anaerobic digestion, fermentation) or chemical (esterification) where direct combustion can provide a direct near-term energy solution (Arias et al., 2008). Some of the inherent problems with raw biomass materials, like low bulk density, high moisture content, hydrophilic nature and low calorific value, limit the ease of use of biomass for energy purposes (Arias et al., 2008). In fact, due to its low energy density compared to fossil fuels, high volumes of biomass will be needed; adding to problems associated with storage, transportation and feed handling at a cogeneration plant. Furthermore, grinding biomass pulverizes, can be very costly and in some cases impractical. All of these drawbacks have given rise to the development of new technologies in order to increase the quality of biomass fuels. The purpose of the work is mainly in four areas 1) Overview of the torrefaction process and to do a literature review on i) Physical properties of torrefied raw material and torrefaction gas composition. 2) Basic principles in design of packed bed i) Equations governing the flow of material in packed bed ii) Equations governing the flow of the gases in packed bed iii) Effect of physical

  16. Rapid SAR and GPS Measurements and Models for Hazard Science and Situational Awareness

    Science.gov (United States)

    Owen, S. E.; Yun, S. H.; Hua, H.; Agram, P. S.; Liu, Z.; Moore, A. W.; Rosen, P. A.; Simons, M.; Webb, F.; Linick, J.; Fielding, E. J.; Lundgren, P.; Sacco, G. F.; Polet, J.; Manipon, G.

    2016-12-01

    The Advanced Rapid Imaging and Analysis (ARIA) project for Natural Hazards is focused on rapidly generating higher level geodetic imaging products and placing them in the hands of the solid earth science and local, national, and international natural hazard communities by providing science product generation, exploration, and delivery capabilities at an operational level. Space-based geodetic measurement techniques such as Interferometric Synthetic Aperture Radar (InSAR), Differential Global Positioning System (DGPS), SAR-based change detection, and image pixel tracking have recently become critical additions to our toolset for understanding and mapping the damage caused by earthquakes, volcanic eruptions, landslides, and floods. Analyses of these data sets are still largely handcrafted following each event and are not generated rapidly and reliably enough for response to natural disasters or for timely analysis of large data sets. The ARIA project, a joint venture co-sponsored by California Institute of Technology (Caltech) and by NASA through the Jet Propulsion Laboratory (JPL), has been capturing the knowledge applied to these responses and building it into an automated infrastructure to generate imaging products in near real-time that can improve situational awareness for disaster response. In addition, the ARIA project is developing the capabilities to provide automated imaging and analysis capabilities necessary to keep up with the imminent increase in raw data from geodetic imaging missions planned for launch by NASA, as well as international space agencies. We will present the progress we have made on automating the analysis of SAR data for hazard monitoring and response using data from Sentinel 1a/b as well as continuous GPS stations. Since the beginning of our project, our team has imaged events and generated response products for events around the world. These response products have enabled many conversations with those in the disaster response community

  17. Décadas de oro de la centenaria SMP

    OpenAIRE

    Duque Escobar, Gonzalo

    2012-01-01

    Aportes de la SMP hasta el Centenario de Manizales, de este espacio cívico creado en 1912 cuando Aquilino Villegas y Alfonso Robledo convocan a notables ciudadanos de la próspera aldea, como Alfonso Villegas, Carlos E. Pinzón, Constantino Gutiérrez, Estanislao Estrada, Fernando Arango, Francisco Gutiérrez, Gonzalo Villegas, Jesús María Arias, Liborio Gutiérrez, Luis Londoño, Pedro Henao y Pompilio Gutiérrez.

  18. Letras de Caldas. El panorama de la cuentística

    Directory of Open Access Journals (Sweden)

    Adel López Gómez

    1966-08-01

    Full Text Available En amplia, documental, beligerante y pungente conferencia pronunciada hace algún tiempo en el Teatro de los Fundadores de Manizales, el joven crítico y escritor Jaime Mejía Duque, al enjuiciar severamente la literatura de Caldas y -concretamente- el llamado greco-quimbayismo, cuya más alta personería señala en Aquilino y Silvio Villegas y Bernardo Arias Trujillo, nos hace gracia de excepción a los cuentistas.

  19. El obispo que estuvo a punto de ser procesado. Antonio Palenzuela y la «cárcel concordataria» de Zamora

    Directory of Open Access Journals (Sweden)

    Martín de Santa Olalla Saludes, Pablo

    2009-06-01

    Full Text Available The present article is centred in one of the conflicts less known about relations Catholic Church-Spanish State after Council Vatican II: the one who could be called «case Palenzuela», a matter of possible indictment that never went so far as to take place because of the events in spanish politics (the change in Presidency of Government, when Carlos Arias Navarro relieved murdered Admiral Carrero Blanco, betting for a line of dialogue opened with the Holy See (fastly frustrated by facts like «case Añoveros» that, in any case, never went so far as to obtain fruits of authentic trascendency.El presente artículo se centra en uno de los conflictos menos conocidos de las relaciones Iglesia-Estado en el Posconcilio: el que podríamos llamar caso Palenzuela, un asunto de posible enjuiciamiento que nunca llegó a producirse por el devenir de la política española, que conllevó un cambio en el Gobierno (Carlos Arias Navarro en lugar del fallecido Almirante Carrero Blanco en el que se apostó por una línea de diálogo abierto con la Santa Sede (rápidamente frustrada por hechos como el caso Añoveros que, sin embargo, nunca llegó a obtener frutos de auténtica trascendencia.

  20. Una especie nueva de Strombocactus (Cactaceae del río Moctezuma, Querétaro, México A new species of Strombocactus (Cactaceae from Moctezuma River, Querétaro, Mexico

    Directory of Open Access Journals (Sweden)

    Salvador Arias

    2010-12-01

    Full Text Available Se describe e ilustra Strombocactus corregidorae S. Arias et E. Sánchez, nueva especie del cañón del Infiernillo, en el río Moctezuma, en los límites del estado de Querétaro con Hidalgo. Difiere de S. disciformis por presentar cuerpos más prominentes, con espinas de mayor tamaño, rígidas, gruesas, persistentes y de color negro grisáceo, flores amarillas, así como semillas con células de paredes periclinales planas, microrrelieve finamente reticulado y la región hilo-micropilar no está cubierta por un estrofíolo. Se incluye una clave taxonómica para la identificación de las especies de Strombocactus , con base en caracteres del tallo, flor y la semilla.Strombocactus corregidorae S. Arias et E. Sanchez, from the Infiernillo Canyon, in the Moctezuma River, at the border between the Mexican states of Querétaro and Hidalgo, is described and illustrated. It differs from S. disciformis by its massive body, larger, strong, thick, persistent, black-gray spines, yellow flower, seeds with flat periclinal wall cells, finely reticulate micro-relief, and hilum-micropylar region not covered by a strophiole. An identification key to Strombocactus species, based on stem, flower, and seed characters is included.

  1. Tutto (o quasi) sulle onde

    CERN Document Server

    Pierce, John R

    1977-01-01

    Molti dei fenomeni in cui s'imbatte quotidianamente possono essere interpretati in modo semplice alla luce di quello che è uno dei concetti unificanti della fisica, il concetto di onda: dalle onde acustiche che si propagano nell'aria a quelle luminose, dalle onde radio alle onde meccaniche dei cristalli di quarzo impiegati per controllare la frequenza dei radiotrasmettitori, dalle onde sismiche alle onde di probabilità studiate dalla meccanica quantistica, fino alle onde del linguaggio comune, quelle che muovono la superficie dell'acqua.

  2. Bibliografía

    OpenAIRE

    Álvarez, Ramiro

    2012-01-01

    Arias Galicia, F. ntroducción a la técnica de investigación en ciencias de la administración y del comportamiento.México: Ed. Trillas, 1978. / Kriesberg, L.Sociología de los conflictos sociales.Traducido del Inglés. México; Ed. Trillas, 1975, pp. 355 / Herriot, P. Introducción a la Psicología del Lenguaje. Traducido del inglés. Barcelona: Ed. Labor S. A., 1977, pp. 246.

  3. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision

    NARCIS (Netherlands)

    Brożek, Jan L.; Bousquet, Jean; Agache, Ioana; Agarwal, Arnav; Bachert, Claus; Bosnic-Anticevich, Sinthia; Brignardello-Petersen, Romina; Canonica, G. Walter; Casale, Thomas; Chavannes, Niels H.; Correia de Sousa, Jaime; Cruz, Alvaro A.; Cuello-Garcia, Carlos A.; Demoly, Pascal; Dykewicz, Mark; Etxeandia-Ikobaltzeta, Itziar; Florez, Ivan D.; Fokkens, Wytske; Fonseca, Joao; Hellings, Peter W.; Klimek, Ludger; Kowalski, Sergio; Kuna, Piotr; Laisaar, Kaja-Triin; Larenas-Linnemann, Désirée E.; Lødrup Carlsen, Karin C.; Manning, Peter J.; Meltzer, Eli; Mullol, Joaquim; Muraro, Antonella; O'Hehir, Robyn; Ohta, Ken; Panzner, Petr; Papadopoulos, Nikolaos; Park, Hae-Sim; Passalacqua, Gianni; Pawankar, Ruby; Price, David; Riva, John J.; Roldán, Yetiani; Ryan, Dermot; Sadeghirad, Behnam; Samolinski, Boleslaw; Schmid-Grendelmeier, Peter; Sheikh, Aziz; Togias, Alkis; Valero, Antonio; Valiulis, Arunas; Valovirta, Erkka; Ventresca, Matthew; Wallace, Dana; Waserman, Susan; Wickman, Magnus; Wiercioch, Wojtek; Yepes-Nuñez, Juan José; Zhang, Luo; Zhang, Yuan; Zidarn, Mihaela; Zuberbier, Torsten; Schünemann, Holger J.

    2017-01-01

    Background: Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of life and school and work performance and is a frequent reason for office visits in general practice. Medical costs are large, but avoidable costs associated with lost work productivity are even larger than

  4. Eliidi kesksusest / Fredo Arias-King ; tõlk. Riita-Ilona Märka

    Index Scriptorium Estoniae

    Arias-King, Fredo

    2003-01-01

    Eliidi- ja juhtimisteooria ei pruugi seletada, miks ühes riigis tekkis demokraatia ja teises mitte, kuid ta näitab põhjuseid, miks mõnes postkommunistlikus riigis toimus edukas üleminek demokraatiale või turumajandusele, teises see aga ebaõnnestus. Tabelid. Tõlgitud käsikirjast "The centrality of elites"

  5. Rapid Flood Map Generation from Spaceborne SAR Observations

    Science.gov (United States)

    Yun, S. H.; Liang, C.; Manipon, G.; Jung, J.; Gurrola, E. M.; Owen, S. E.; Hua, H.; Agram, P. S.; Webb, F.; Sacco, G. F.; Rosen, P. A.; Simons, M.

    2016-12-01

    The Advanced Rapid Imaging and Analysis (ARIA) team has responded to the January 2016 US Midwest Floods along the Mississippi River. Daily teleconferences with FEMA, NOAA, NGA, and USGS, provided information on precipitation and flood crest migration, based on which we coordinated with the Japanese Aerospace Exploration Agency (JAXA) through NASA headquarters for JAXA's ALOS-2 timely tasking over two paths. We produced flood extent maps using ALOS-2 SM3 mode Level 1.5 data that were provided through the International Charter and stored at the US Geological Survey's Hazards Data Distribution System (HDDS) archive. On January 6, the first four frames (70 km x 240 km) were acquired, which included the City of Memphis. We registered post-event SAR images to pre-event images, applied radiometric calibration, took a logarithm of the ratio of the two images. Two thresholds were applied to represent flooded areas that became open water (colored in blue) and flooded areas with tall vegetation (colored in red). The second path was acquired on January 11 further down along the Mississippi River. Seven frames (70 km x 420 km) were acquired and flood maps were created in the similar fashion. The maps were delivered to the FEMA as well as posted on ARIA's public website. The FEMA stated that SAR provides inspection priority for optical imagery and ground response. The ALOS-2 data and the products have been a very important source of information during this response as the flood crest has moved down stream. The SAR data continue to be an important resource during times when optical observations are often not useful. In close collaboration with FEMA and USGS, we also work on other flood events including June 2016 China Floods using European Space Agency's (ESA's) Sentienl-1 data, to produce flood extent maps and identify algorithmic needs and ARIA system's requirements to automate and rapidly produce and deliver flood maps for future events. With the addition of Sentinel-1B

  6. Global Rapid Flood Mapping System with Spaceborne SAR Data

    Science.gov (United States)

    Yun, S. H.; Owen, S. E.; Hua, H.; Agram, P. S.; Fattahi, H.; Liang, C.; Manipon, G.; Fielding, E. J.; Rosen, P. A.; Webb, F.; Simons, M.

    2017-12-01

    As part of the Advanced Rapid Imaging and Analysis (ARIA) project for Natural Hazards, at NASA's Jet Propulsion Laboratory and California Institute of Technology, we have developed an automated system that produces derived products for flood extent map generation using spaceborne SAR data. The system takes user's input of area of interest polygons and time window for SAR data search (pre- and post-event). Then the system automatically searches and downloads SAR data, processes them to produce coregistered SAR image pairs, and generates log amplitude ratio images from each pair. Currently the system is automated to support SAR data from the European Space Agency's Sentinel-1A/B satellites. We have used the system to produce flood extent maps from Sentinel-1 SAR data for the May 2017 Sri Lanka floods, which killed more than 200 people and displaced about 600,000 people. Our flood extent maps were delivered to the Red Cross to support response efforts. Earlier we also responded to the historic August 2016 Louisiana floods in the United States, which claimed 13 people's lives and caused over $10 billion property damage. For this event, we made synchronized observations from space, air, and ground in close collaboration with USGS and NOAA. The USGS field crews acquired ground observation data, and NOAA acquired high-resolution airborne optical imagery within the time window of +/-2 hours of the SAR data acquisition by JAXA's ALOS-2 satellite. The USGS coordinates of flood water boundaries were used to calibrate our flood extent map derived from the ALOS-2 SAR data, and the map was delivered to FEMA for estimating the number of households affected. Based on the lessons learned from this response effort, we customized the ARIA system automation for rapid flood mapping and developed a mobile friendly web app that can easily be used in the field for data collection. Rapid automatic generation of SAR-based global flood maps calibrated with independent observations from

  7. LOS PELIGROS DEL DOBLE DISCURSO. DE LO INTERNACIONAL A LO LOCAL: El caso de la propuesta “Costa Rica Carbono Neutral - 2021”

    Directory of Open Access Journals (Sweden)

    Javier Baltodano Aragón

    2008-12-01

    Full Text Available Resumen Este trabajo analiza algunos aspectos de las negociaciones e iniciativas que intentan enfrentar el cambio climático a nivel internacional, poniendo énfasis en los mecanismos de compensación y la creación de los mercados de carbono, su significado en relación a  la creación de “derechos de propiedad sobre la contaminación de la atmósfera” y en relación a la efectividad  que estos esquemas tienen para  enfrentar el Cambio Climático. Asimismo, se analiza su vinculación con la propuesta del actual gobierno de Costa Rica (Oscar Arias Sánchez, 2006-2010 denominada “Costa Rica, Carbono Neutral para el año 2021” y su pertinencia para enfrentar el Cambio Climático en nuestro país.  Abstract This document analyzes some aspects of the international negotiations and initiatives that intent to face out Climate Change. It put emphasis on the offset mechanisms and carbon markets, their meaning in terms of the creation of “property” over the atmosphere contamination rights and in term of their efficiency to face the Climate Change.  It also analyzes the relationship of these initiatives with the actual Costa Rican Government (Oscar Arias Sánchez, 2006-2010 proposal, named “Costa Rica, Carbon Neutral 2021” and its adequacy to confront Climate Change in the country.

  8. Mecenazgo religioso y estrategias familiares en la Segovia del siglo XV: Diego Árias de Ávila y el Hospital de San Antonio

    Directory of Open Access Journals (Sweden)

    Rábade Obradó, María del Pilar

    2002-12-01

    Full Text Available The present work studies the foundation of Saint Anthony´s hospital of Segovia during the XVth century. The foundation was an initiative of Diego Arias de Ávila, one of the most influential personalities of the reign of Henry IV of Castila. The foundation was determined on very varied reasons, not only charitative and religious reasons. Among these reasons, the use of the hospital as an instrument of the family strategies. These family strategies tried to hidden the hebrew origins of the lineage. They also tried to guarantee the perennity of the lineage, and to leave an endurable memory behind. Lasdy, these family strategies tried to consolidate the domination that the lineage had on Segovia.

    El presente trabajo estudia la fundación del hospital de San Antonio de Segovia en el siglo XV. La fundación fue una iniciativa de Diego Arias de Ávila, uno de los personajes más influyentes durante el reinado de Enrique IV de Castilla. La fundación estuvo determinada por motivaciones muy diversas, no sólo caritativas y religiosas. Entre ellas, el uso del hospital como instrumento de las estrategias familiares. Esas estrategias familiares pretendían ocultar los orígenes judíos del linaje, garantizar su perennidad, dejar una memoria perdurable del mismo, y, finalmente, consolidar la dominación que el linaje ejercía sobre Segovia.

  9. Fenomeni troposferici di trasporto e diffusione a grande scala posti in evidenza da traccianti radioattivi

    Directory of Open Access Journals (Sweden)

    ADRIANO GAZZOLA

    1962-06-01

    Full Text Available In Meteorologia, tra i problemi che presentano maggior difficoltà, siaper Vindagine teorica che per quella sperimentale, vi sono quelli relativialla determinazione delle traiettorie delle masse d'aria nei loro moti orizzontalie verticali, e quelli relativi alla valutazione dei fenomeni di diffusioneche accompagnano tali moti.Si pensi che le traiettorie, relativamente brevi nei fenomeni « locali »,giungono a compiere anche uno o più volte il giro del globo.Analogamente, e in particolare, i fenomeni di diffusione si svolgonoa scale estremamente diverse: da quella submicroscopica molecolare deglistrati aderenti al stiolo, a quella continentale od emisferica delle onde cicloniche.Infatti nei processi di « scambio » fra strati sovrapposti o adiacenti,da percorsi del milionesimo di millimetro e tempi di percorso del centomilionesimodi secondo, si passa a percorsi di migliaia e decine di migliaiadi chilometri con tempi dell'ordine del giorno o della settimana.Cosicché i relativi coefficienti di diffusione variano fra valori i cuiestremi stanno fra loro come uno a un migliaio di miliardi.Tra i fenomeni permanenti o saltuari, dovuti alla natura o agli esperimentidell'uomo, che possono agevolare le ricerche sui moti delle massed'aria e sulla loro diffusione, sono di particolare ausilio quelli della radioattivitànaturale e della radioattività artificiale.Le sostanze radioattive possono infatti essere utilizzate nell'atmosferacome « traccianti », in modi analoghi a quelli coi quali esse sono utilizzatenegli studi di biologia e medicina.

  10. Stability of the Spanish version of the five-item Francis Scale of Attitude toward Christianity.

    Science.gov (United States)

    Miranda-Tapia, Giskar Alonso; Cogollo, Zuleima; Herazo, Edwin; Campo-Arias, Adalberto

    2010-12-01

    The aim of this study was to establish test-retest reliability of a Spanish version of the Francis Scale of Attitude toward Christianity (Campo-Arias, Oviedo, & Cogollo, 2009) among adolescent students in Cartagena, Colombia. A group of ninth grade students from two public schools in Colombia (N = 157) completed the five-item scale. Cronbach's alphas were .74 and .76 in the first and second administrations, respectively. Both Pearson's rho and intra-class correlation coefficient were .69. A Spanish translation of the 5-item scale had consistent stability over four weeks.

  11. Gender Performativity and Cross Dressing through some Stagings of Genet’s The Maids

    Directory of Open Access Journals (Sweden)

    Ezequiel Lozano

    2013-09-01

    Full Text Available This article explores the concepts of cross dressing and gender performativity through the conceptualization of queer studies, exemplifying them with successive stagings of The Maids, by Jean Genet. It focuses specifically on Argentine directors, whose common feature lies not only in the dramatic text but in objections to the idea of representation, as Genet suggests in his text. S. Renán, V. García, A. Arias and C. Zorzoli problematise this idea, with each new staging, and allow us to reflect on the destabilization operated by The Maids.

  12. ¡Atención! Tenga precaución con alguien que haya sufrido una conmoción cerebral

    Centers for Disease Control (CDC) Podcasts

    Todos los años, en los Estados Unidos se registran hasta 3.8 millones de casos de conmoción cerebral en actividades deportivas o recreativas. Este Podcast es una entrevista por radio con la Dra. Ileana Arias sobre la iniciativa titulada "Atención: conmoción cerebral en el deporte juvenil" de CDC que ofrece información a los entrenadores, los padres y los atletas sobre prevención, reconocimiento y reacción frente a una conmoción.

  13. La inútil añoranza de la normalidad

    Directory of Open Access Journals (Sweden)

    Margarita Valencia

    2012-01-01

    Full Text Available Litchis de Madagascar. Aquiles Cuervo. Editorial Elfin de la noche. Buenos Aires, 2011, 91 págs. El ruido de las cosas al caer. Juan Gabriel Vásquez. Premio Alfaguara de novela 2011. Alfaguara. Bogotá. 2011, 259 págs. Tres ataúdes blancos. Antonio Ungar. Premio Herralde de Novela. Editorial Anagrama. Barcelona. 2010, 259 págs. Suicídame. Andrés Arias. Ediciones B. Bogotá, 2010, 261 págs. C.M. no récord. Juan Álvarez. Alfaguara. Bogotá, 2010, 262 págs.

  14. Resistencia bacteriana:sinergismo in vitro y eficacia clínica del tratamiento antimicrobiano en neonatos sépticos

    OpenAIRE

    Espino Hernández, María Hildelisa

    2009-01-01

    Este trabajo tuvo como objetivo determinar la etiología y susceptibilidad de los agentes causales de sepsis neonatal y la eficacia clínica del tratamiento antimicrobiano por pruebas de sinergismo in vitro, en el Hospital Ginecobstétrico Universitario "América Arias", durante el periodo comprendido desde enero de 1993 a diciembre 2000. Se definieron los patrones de resistencia de 533 cepas aisladas de los recién nacidos frente a los ß-lactámicos y aminoglucósidos, y se evaluó, por el método de...

  15. A mercantilização da magia na urbanização de São Paulo, 1910-1940

    Directory of Open Access Journals (Sweden)

    Maria Cristina Cortez Wissenbach

    2004-06-01

    Full Text Available Com base em processo movidos contra réus incursos nos artigos que criminalizavam o curandeirismo, o espiritismo, a feitiçaria e outras práticas similares, o texto busca o significado histórico de crenças religiosas na perspectiva de um universo citadino em transformação. Contempla questões como a propagação do espiritismo, diferenças entre rituais do "baixo" e do "alto" espiritualismo e o tratamento dado ao tema pela imprensa e pelas autoridades que lideravam as campanhas antimagia.

  16. Variational Framework for Non-Local Inpainting

    Directory of Open Access Journals (Sweden)

    Vadim Fedorov

    2015-12-01

    Full Text Available Image inpainting aims to obtain a visually plausible image interpolation in a region of the image in which data is missing due to damage or occlusion. Usually, the only available information is the portion of the image outside the inpainting domain. Besides its numerous applications,the inpainting problem is of theoretical interest since its analysis involves an understanding of the self-similarity present in natural images. In this work, we present a detailed description and implementation of three exemplar-based inpainting methods derived from the variational framework introduced by Arias et al.

  17. Air conditioning sector marketing. Situazione nel settore del condizionamento dell'aria

    Energy Technology Data Exchange (ETDEWEB)

    Wurm, J.; Biederman, R. (Institute of Gas Technology, Chicago, IL (United States))

    1993-03-01

    Predictions are that the space heating ventilation and air conditioning equipment sector will undergo significant expansion in the coming decade. Substantial technology inputs will be required to make new equipment conform to standards on energy efficiency and environmental compatibility, and strong competition in this sector will force equipment designers to seek low energy cost solutions. The European energy price situation is expected to favour the use of reversible gas heat pumps in space HVAC systems for buildings. New environmental regulations, especially those governing refrigerant typology, indoor air pollution and thermal comfort in office buildings, should also help to increase demand for new technologically advanced equipment conforming with international standards.

  18. A WAO - ARIA - GA²LEN consensus document on molecular-based allergy diagnostics.

    Science.gov (United States)

    Canonica, Giorgio Walter; Ansotegui, Ignacio J; Pawankar, Ruby; Schmid-Grendelmeier, Peter; van Hage, Marianne; Baena-Cagnani, Carlos E; Melioli, Giovanni; Nunes, Carlos; Passalacqua, Giovanni; Rosenwasser, Lanny; Sampson, Hugh; Sastre, Joaquin; Bousquet, Jean; Zuberbier, Torsten

    2013-10-03

    Molecular-based allergy (MA) diagnostics is an approach used to map the allergen sensitization of a patient at a molecular level, using purified natural or recombinant allergenic molecules (allergen components) instead of allergen extracts. Since its introduction, MA diagnostics has increasingly entered routine care, with currently more than 130 allergenic molecules commercially available for in vitro specific IgE (sIgE) testing.MA diagnostics allows for an increased accuracy in allergy diagnosis and prognosis and plays an important role in three key aspects of allergy diagnosis: (1) resolving genuine versus cross-reactive sensitization in poly-sensitized patients, thereby improving the understanding of triggering allergens; (2) assessing, in selected cases, the risk of severe, systemic versus mild, local reactions in food allergy, thereby reducing unnecessary anxiety for the patient and the need for food challenge testing; and (3) identifying patients and triggering allergens for specific immunotherapy (SIT).Singleplex and multiplex measurement platforms are available for MA diagnostics. The Immuno-Solid phase Allergen Chip (ISAC) is the most comprehensive platform currently available, which involves a biochip technology to measure sIgE antibodies against more than one hundred allergenic molecules in a single assay. As the field of MA diagnostics advances, future work needs to focus on large-scale, population-based studies involving practical applications, elucidation and expansion of additional allergenic molecules, and support for appropriate test interpretation. With the rapidly expanding evidence-base for MA diagnosis, there is a need for allergists to keep abreast of the latest information. The aim of this consensus document is to provide a practical guide for the indications, determination, and interpretation of MA diagnostics for clinicians trained in allergology.

  19. Actitudes de estudiantes sobre personas con discapacidad en la universidad del Bío-Bío

    Directory of Open Access Journals (Sweden)

    Carlos Ossa Cornejo

    2013-01-01

    Full Text Available Abstract In this research paper, a questionnaire of attitudes towards people with disabilities was applied in a sample of five careers at the Universidad del Bio-Bio, in Chile, where disabled people are currently studying. This questionnaire was constructed by Verdugo, Jenaro and Arias (1997. We found that there is a fairly high level of student contact in the sample with disabled people (62%, and the frequency of contact is mostly sporadic (38%. While the total valuation of the sample participants showed an average valoration of 182 (maximun of 222 that is judged as well. Also, two subscales related beliefs and roles assumed by people with disabilities had a fairly good evaluation. Resumen Este artículo de investigación se refiere a los resultados de la aplicación del Cuestionario de Actitudes hacia las Personas con Discapacidad de Verdugo, Jenaro y Arias (1997, en una muestra de estudiantes de cinco carreras de la Universidad del Bío-Bío. Se encontró que existe un nivel medianamente alto de contacto de los estudiantes de la muestra con personas con discapacidad (62%, y que la frecuencia de contacto es mayoritariamente esporádica (38%. Si bien la valoración total de los participantes de la muestra arrojó un resultado promedio de 182 (máximo de 222, que se juzga como bueno, dos subescalas, relacionadas con las creencias y los roles que asumen las personas con discapacidad, solo alcanzaron un promedio medianamente bueno.

  20. Plan Exportador FA. INTI.

    OpenAIRE

    Herrera Arias, Francisco

    2009-01-01

    El desarrollo del presente trabajo de grado, constituye un trabajo en equipo entre la Secretaria de Desarrollo Económico de la Alcaldía Mayor de Bogotá D.C., el CIDEM de la Universidad del Rosario y Maloka. La metodología aplicada del CIDEM a la empresa FA. INTI. se ha aplicado a mas de 1000 PYMES colombianas y ha sido coordinada por Francisco Herrera Arias y dirigida por la Dr. Luz Sofía Méndez y un equipo profesional de consultores. El plan exportador cuenta con información general de la em...

  1. An Interview with Professor Melquíades de Dios Leyva, December 2008

    Science.gov (United States)

    Arias de Fuentes, Olimpia

    When writing about the history of physics in Cuba, this remarkable professor of quantum mechanics must be mentioned, for he embodies a most genuine example of the turn taken by national educational policy after 1959: Education for all, at all levels, with no discrimination or elitism. The following is an interview granted by Dr. Melquíades de Dios Leyva, Outstanding Full Professor of the Physics Faculty of the University of Havana, to Dr. Olimpia Arias de Fuentes, Associate Professor at the same, and Senior Researcher of the Institute of Materials Science and Technology (IMRE) of the University of Havana.

  2. Dicty_cDB: Contig-U03328-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available aria DNA, clone: DAB1-004E12.F.fa, ... 48 0.16 1 ( EC770709 ) EST 7205 Guarana fruits cDNA library Paul...... 44 2.4 1 ( EI726036 ) 2B421023C20TR BAC library from breast tumor sampl... 44...s sativus) mature stigma l... 44 2.4 1 ( EV118860 ) 0124172 Brassica napus Root lib...rary Brassica napu... 44 2.4 1 ( ES560299 ) B79 Ascochyta rabiei induced library Cicer arieti..... 50 0.040 1 ( BM027318 ) GIT0000656 Root-induced cDNA library from Glomus ... 50 0.040 1 ( BI505723 ) BB17

  3. El Dimoni de Maxwell

    OpenAIRE

    Monserrat, Bartomeu

    2010-01-01

    El dimoni de Maxwell és el resultat d'un experiment mental que va proposar el físic escocès James Clerk Maxwell (1831-1879), que si es complís amenaçaria la validesa de la segona llei de la termodinàmica. Segons aquest experiment, seria possible la transmissió de calor d'un cos a un altre de més calent sense cap altre canvi. S'hi ex- posen diverses solucions, que van des de la interacció entre la mesura i el sistema mesurat, fins a la teoria de la informació. Aquest article, origi...

  4. In Memoriam Jerome Bruner (1915-2016

    Directory of Open Access Journals (Sweden)

    Walter L. Arias Gallegos

    2016-10-01

    Full Text Available El 5 de junio último, Jerome Bruner falleció en New York, de manera imprevista, pero a la vez indolora y apacible. Bruner ha sido uno de los psicólogos más influyentes del siglo XX a través de su labor académica en los campos de la psicología educativa y la psicología narrativa, donde ha alcanzado notoriedad, pero también se ha dedicado a la psicología militar, a la psicología culturalista y, más recientemente, a la psicología forense (Arias, 2015.

  5. U.S. Navy Hindcast Spectral Ocean Wave Model Climatic Atlas: Mediterranean Sea

    Science.gov (United States)

    1990-01-01

    8217 (total) were obtained by summing the percent frequencies across each row. Rounding may cause minor differences between printed totals and total cell counts...34c9 3 N6 l7 4, i 5E F TI + e "t1- 4TI 3- ’$69"- -’ - + el4 𔄃 t 14 t , + t. -. ----- + 13,, 6 6 , 4- +0 2 4 9,: o . ;.. .;,+ + 5 ., 𔃿 6.--’ r’ ---- ’p...The SOWM generates ’en-.!rgy ’ariaLLcb’ cell within the 180 element matrix f The output from a SOWM hindcast includes a wind fields. There is a

  6. MP-AzeFlu provides rapid and effective allergic rhinitis control: results of a non-interventional study in Romania.

    Science.gov (United States)

    Agache, I; Doros, I C; Leru, P M; Bucur, I; Poenaru, M; Sarafoleanu, C

    2018-03-01

    Allergic Rhinitis and its Impact on Asthma (ARIA) and the European Union (EU) recommend a shift to guide allergic rhinitis (AR) treatment decisions from symptom severity to disease control, using a simple visual analogue scale (VAS). Using this VAS we assessed, in a real-life study in Romania, the effectiveness of MP-AzeFlu nasal spray. In this multi-centre, prospective, non-interventional study, 253 patients (over 11 years old) with moderate-to-severe AR were prescribed MP-AzeFlu and assessed their symptoms on a VAS (0 (not at all bothersome) to 100 mm (very bothersome)) on Days 0, 1, 3, 7 and 14. The proportion of patients who achieved a defined VAS score cut-off for well-controlled (38 mm) AR were also calculated. Patients perception of disease control was assessed on Day 3. MP-AzeFlu use was associated with a mean (standard deviation) VAS score reduction from 78.4 (15.1) mm at baseline to 14.7 (15.1) mm on the last day. Effectiveness was consistent irrespective of disease severity, phenotype or patient age. 83.4% of patients achieved the smaller than 39 mm well-controlled VAS score cut-off by last day and 95.2% considered their symptoms to be well- or partly controlled at Day 3. MP-AzeFlu provided rapid, effective and sustained AR symptom control in a real-life setting in Romania, irrespective of severity, phenotype or patient age, aligning with ARIA and EU recommendations and supporting the position of MP-AzeFlu as the drug of choice for the treatment of moderate-to-severe AR.

  7. Indoor randon concentration. Temperature and wind effects; Concentrazione di radon indoor. Effetto del vento e della temperatura

    Energy Technology Data Exchange (ETDEWEB)

    Sesana, L.; Benigni, S. [Milan Univ., Milan (Italy). Ist. di Fisica Generale Applicata

    2000-12-01

    The present study analyses and discusses the behaviour of the indoor radon concentration in a research house. Hourly measurements were carried out in the basement of the house from November 1998 up to June 1999. In many sequences of days radon concentration in the room under analysis shows strong variation all day long with accumulation in the evening and overnight and decrease in the morning and in the afternoon. Measurements of wind velocity, indoor and outdoor temperatures and outdoor-indoor pressure difference were performed and their trend is compared with the observed radon concentration. The exhalation of radon from walls, floor and ceiling and the pressure difference driven exhalation from the soil are discussed, particularly the relation with the temperature differences. The air exchange rates between the house and the outdoor air are studied. [Italian] Si analizza e si discute il comportamento della concentrazione di radon indoor nel seminterrato di una casa di ricerca. Misure orarie sono state effettuate da novembre 1998 a giugno 1999. In molte sequenze di giorni la concentrazione del radon nel locale in analisi presenta forti variazioni nel corso della giornata con un accumulo notturno e decrescita nelle ore diurne. Sono state eseguite misure della velocita' del vento, delle temperature outdoor e indoor e della differenza di pressione outdoor-indoor e il loro andamento e' stato confrontato con quello della concentrazione del radon. Vengono discusse l'esalazione del radon dalle pareti, dal pavimento e dal soffitto e l'esalazione pressure difference driven dal suolo. Il rateo dei ricambi d'aria tra il locale e l'aria outdoor e' studiato.

  8. NMR studies of the sporulation protein SpoIIAA: Implications for the regulation of the transcription factor {sigma}F in Bacillus subtilis

    Energy Technology Data Exchange (ETDEWEB)

    Kovacs, Helena; Comfort, David; Lord, Matthew; Yudkin, Michael; Campbell, Iain D.; Nilges, Michael

    2001-04-15

    SpoIIAA participates in a four-component mechanism for phosphorylation-dependent transcription control at the outset of sporulation. We report the refinement of the solution structure of SpoIIAA by using the automated iterative NOE assignment method ARIA. To complement the structural data, the protein dynamics were determined by measuring the T{sub 1}, T{sub 2} and NOE of the backbone {sup 15}N-nuclei. The refined structure permits a discussion of the structural features that are important for the function of SpoIIAA in the regulation of the sporulation sigma factor {sigma}{sup F}, and for homologous regulatory pathways present in B. subtilis and in other bacilli.

  9. NMR studies of the sporulation protein SpoIIAA: Implications for the regulation of the transcription factor σF in Bacillus subtilis

    International Nuclear Information System (INIS)

    Kovacs, Helena; Comfort, David; Lord, Matthew; Yudkin, Michael; Campbell, Iain D.; Nilges, Michael

    2001-01-01

    SpoIIAA participates in a four-component mechanism for phosphorylation-dependent transcription control at the outset of sporulation. We report the refinement of the solution structure of SpoIIAA by using the automated iterative NOE assignment method ARIA. To complement the structural data, the protein dynamics were determined by measuring the T 1 , T 2 and NOE of the backbone 15 N-nuclei. The refined structure permits a discussion of the structural features that are important for the function of SpoIIAA in the regulation of the sporulation sigma factor σ F , and for homologous regulatory pathways present in B. subtilis and in other bacilli

  10. Los cuentos tristes

    Directory of Open Access Journals (Sweden)

    Alberto Aguirre

    1993-01-01

    Full Text Available La casa del ruego y de la lluvia. Milciades Arévalo. 1992, 119 págs. Esta risa no es de loco. Medardo Arias Satizábal. 1992, 70 págs. La caja de música. Mauricio Peñaranda Castillo. 1992, 69 págs. Mariposas negras sobre la ciudad. Jesús Rincón Murcia. 1992, 167 págs. Acerca y de lejos. Celso Román. 1992, 127 págs. El informe de Galves. Roberto Rubiano Vargas. 1992, 137 págs. El retablo del reposo. Guido Leonardo Tamayo. 1991, 87 págs.

  11. Usability and Accessibility of eBay by Screen Reader

    Science.gov (United States)

    Buzzi, Maria Claudia; Buzzi, Marina; Leporini, Barbara; Akhter, Fahim

    The evolution of Information and Communication Technology and the rapid growth of the Internet have fuelled a great diffusion of eCommerce websites. Usually these sites have complex layouts crowded with active elements, and thus are difficult to navigate via screen reader. Interactive environments should be properly designed and delivered to everyone, including the blind, who usually use screen readers to interact with their computers. In this paper we investigate the interaction of blind users with eBay, a popular eCommerce website, and discuss how using the W3C Accessible Rich Internet Applications (WAI-ARIA) suite could improve the user experience when navigating via screen reader.

  12. Digital Optical Circuit Technology.

    Science.gov (United States)

    1985-03-01

    in lergth from 2 to 115 on, with i stra-savity -gas tells as short as 1 mm w-r.- iperati at S;F(. itas ;a’arasrasgqisg from c-i. I to (a. 27001 terr...a.aria,s I iaae iai the I’ LI and I o a 1- TEA ClyzI asir were ’ iso -i to, Lam;il Lb’ dense aaii biroad spectral features s-f tuel , s-rat as-aual as...range of logic operut isos laso upon the two possible out- it levels. This contrasts with GaAs in which, as a result of the ratio of not- linearity to

  13. A WAO - ARIA - GA2LEN consensus document on molecular-based allergy diagnostics

    DEFF Research Database (Denmark)

    Canonica, Giorgio Walter; Ansotegui, Ignacio J; Pawankar, Ruby

    2013-01-01

    Molecular-based allergy (MA) diagnostics is an approach used to map the allergen sensitization of a patient at a molecular level, using purified natural or recombinant allergenic molecules (allergen components) instead of allergen extracts. Since its introduction, MA diagnostics has increasingly ...

  14. Domestic allergens; Gli allergeni domestici

    Energy Technology Data Exchange (ETDEWEB)

    Bressa, G. [Padua Univ., Padua (Italy). DIpt. di Tossicologia Ambientale

    2000-12-01

    Closed rooms can be the ideal habitat for the growth of many micro-organisms, some of which pathogenic for man. Indoor biologic contamination sources can vary: 1) external air can, through dust particles or water droplets, transfer a large number of germs inside the house; 2) air conditioning plants can become, if maintenance isn't carried out at regular intervals, a cultural medium for microbes which later spread to the air of house or office; 3) the presence of sick people or healthy carriers of pathogenic germs in closed rooms can represent a significant source of biologic contamination; 4) lastly, pets too can be considered as disease carriers. Particularly interesting is the so-called biologic dust - where mites proliferate - which, being trapped in curtains, carpeting, tapestry, fabrics and carpets, often causes respiratory system diseases. [Italian] Gli ambienti chiusi possono costituire l'habita ideale per la crescita di molti microorganismi, alcuni dei quali patogeni per l'uomo. Le fonti di contaminaizone biologica indoor possono essere diverse: 1) l'aria esterna puo' trasferire all'interno, attraverso particelle di polvere o goccioline d'acqua, un gran numero di germi; 2) gli impianti di condizionamento possono divenire, quando non si effettua una corretta manutenzione periodica, terreno di coltura di microbi che successivamente si diffondono nell'aria dell'abitazione o dell'ufficio; 3) la presenza in locali chiusi di persone malate o portatrici sane di germi patogeni puo' costituire un'importante sorgente di contaminazione biologica; 4) infine anche gli animali domestici possono essere considerati vettori di malattie. Di particolare interesse sono le polveri cosidette biologiche, in cui proliferano gli acari, che, essendo trattenute da tendaggi, parati, moquette, tessuti e tappeti, provocano frequentemente malattie dell'apparato respiratorio.

  15. Satisfaction and quality of life of allergic patients following sublingual five-grass pollen tablet immunotherapy in Spain

    Science.gov (United States)

    Antolín-Amerigo, Darío; Tabar, Isabel A; del Mar Fernández-Nieto, Maria; Callejo-Melgosa, Anna M; Muñoz-Bellido, Francisco J; Martínez-Alonso, José C; Méndez-Alcalde, Jorge D; Reche, Marta; Rodríguez-Trabado, Ana; Rosado-Ingelmo, Ana; Alonso-Gómez, Alicia; Blanco-González, Rosa; Alvarez-Fernandez, José A; Botella, Isabel; Valls, Ana; Cimarra, Mercedes; Blanco, Carlos

    2017-01-01

    Background Five-grass pollen tablet is an effective and well-tolerated therapy for patients with allergic rhinoconjunctivitis (ARC). This trial sought to determine the satisfaction and health-related quality of life (HRQoL) of patients undergoing this treatment. Methods This was a cross-sectional, multicentre, observational, naturalistic study, following a discontinuous pre- and co-seasonal five-grass pollen regimen over two seasons in Spain (2012, 2013). The HRQoL of the patients was measured with the specific Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) for adults, adolescent (AdolRQLQ), or paediatric (PRQLQ) patients. Treatment satisfaction was assessed by the Satisfaction Scale for Patients Receiving Allergen Immunotherapy (ESPIA) questionnaire. Patients/investigators were surveyed on beliefs and attitudes towards the five-grass pollen tablet. ARC evolution according to allergic rhinitis and its impact on asthma (ARIA) criteria and treatment adherence were evaluated. Results Among the 591 ARC patients included, the mean (SD) HRQoL scores were 1.40 (1.1) in adults, 1.33 (1.1) in adolescents, and 1.15 (1.1) in children, indicating low levels of impairment (scale 0–6). ESPIA answers showed high levels of satisfaction, with an average score of 69.2 (scale 0–100). According to ARIA criteria, 88.2% of patients reported improvement of ARC. Moreover, this was accompanied by a reduced use of symptomatic medication. Adherence to treatment was estimated at 96.8%. In general, both patients and specialists exhibited a positive attitude towards five-grass pollen tablet treatment. Conclusion ARC patients treated with five-grass pollen tablet showed favourable levels of HRQoL and treatment satisfaction, with concomitant improvements in ARC and symptomatic medication use, which translated into high levels of treatment adherence and a positive attitude towards five-grass pollen tablet. PMID:29225657

  16. La radiazione solare (globale e la rete altinometrica del servizio meteorologico dell'aeronautica italiana(*

    Directory of Open Access Journals (Sweden)

    O. DE PASQUALE

    1964-06-01

    Full Text Available Si fa una breve desorizione della funzione degli Osservatori
    Scientifico-Sperimentali del Servizio Meteorologico deU'Aeronautioa,
    militare italiana (OSSMA, con particolare riferimento a quello di Messina,
    clie tra i suoi coinpiti ha anche quello degli studi e delle ricerclie sulla radiazione
    solare, con la gestione di una Rete attinometrica di 31 stazioni.
    Si passa quindi ad una rapida rassegna evocativa degli studi sulla
    radiazione solare su scala mondiale, notificando il contributo italiano e
    mettendo in particolare rilievo quelli della radiazione globale (D -j- I anche
    a scopo sinottico, che formano oggetto di particolari applicazioni da parte
    dell'OSSMA di Messina.
    Inoltre fatta una breve descrizione del funzionamento della Rete attinometrica
    A. M. e del contenuto delle relative pubblicazioni finora fatte
    o in corso, si discutono i risultati ed i metodi di impiego dei dati e si fanno
    voti perche essi vengano introdotti piu attivamente nel campo sinottico
    applicativo, specie in relazione alia turbolenza atmosferica, alia evaporazione
    e quindi alia umiclificazione delle masse d'aria.
    Detti fenomeni, unitamente all'azione delle correnti superflciali marine
    calde, a circolazione ciclonic.a, darebbero luogo, secondo l'autore, alle basse
    barometriche secondarie (Golfo di Genova, Alto Adriatico. . . e ad alcune
    perturbazioni temporalesche. Si auspica pertanto una maggiore collaborazione
    t r a Meteorologia e Oceanografla.
    Inline, in relazione tra i fenomeni sopra detti e l'andamento della
    acqua precipitabile notturna e diurna, ricavata dai radiosondaggi, si emette
    l'ipotesi che una parte dell'ossigeno atoinico atmosferico possa trovare la
    sua origine nella scomposizione delle molecole del vapor d'acqua dell'aria,

  17. E region neutral winds in the postmidnight diffuse aurora during the atmospheric response in aurora 1 rocket campaign

    International Nuclear Information System (INIS)

    Brinkman, D.G.; Walterscheid, R.L.; Lyons, L.R.

    1995-01-01

    Measured E region neutral winds from the Atmospheric Response in Aurora (ARIA 1) rocket campaign are compared with winds predicted by a high-resolution nonhydrostatic dynamical thermosphere model. The ARIA 1 rockets were launched into the postmidnight diffuse aurora during the recovery phase of a substorm. Simulations have shown that electrodynamical coupling between the auroral ionosphere and the thermosphere was expected to be strong during active diffuse auroral conditions. This is the first time that simulations using the time history of detailed specifications of the magnitude and latitudinal variation of the auroral forcing based on measurements have been compared to simultaneous wind measurements. Model inputs included electron densities derived from ground-based airglow measurements, precipitating electron fluxes measured by the rocket, electron densities measured on the rocket, electric fields derived from magnetometer and satellite ion drift measurements, and large-scale background winds from a thermospheric general circulation model. Our model predicted a strong jet of eastward winds at E region heights. A comparison between model predicted and observed winds showed modest agreement. Above 135 km the model predicted zonal winds with the correct sense, the correct profile shape, and the correct altitude of the peak wind. However, it overpredicted the magnitude of the eastward winds by more than a factor or 2. For the meridional winds the model predicted the general sense of the winds but was unable to predict the structure or strength of the winds seen in the observations. Uncertainties in the magnitude and latitudinal structure of the electric field and in the magnitude of the background winds are the most likely sources of error contributing to the differences between model and observed winds. Between 110 and 135 km the agreement between the model and observations was poor because of a large unmodeled jetlike feature in the observed winds

  18. Migration check tool: automatic plan verification following treatment management systems upgrade and database migration.

    Science.gov (United States)

    Hadley, Scott W; White, Dale; Chen, Xiaoping; Moran, Jean M; Keranen, Wayne M

    2013-11-04

    Software upgrades of the treatment management system (TMS) sometimes require that all data be migrated from one version of the database to another. It is necessary to verify that the data are correctly migrated to assure patient safety. It is impossible to verify by hand the thousands of parameters that go into each patient's radiation therapy treatment plan. Repeating pretreatment QA is costly, time-consuming, and may be inadequate in detecting errors that are introduced during the migration. In this work we investigate the use of an automatic Plan Comparison Tool to verify that plan data have been correctly migrated to a new version of a TMS database from an older version. We developed software to query and compare treatment plans between different versions of the TMS. The same plan in the two TMS systems are translated into an XML schema. A plan comparison module takes the two XML schemas as input and reports any differences in parameters between the two versions of the same plan by applying a schema mapping. A console application is used to query the database to obtain a list of active or in-preparation plans to be tested. It then runs in batch mode to compare all the plans, and a report of success or failure of the comparison is saved for review. This software tool was used as part of software upgrade and database migration from Varian's Aria 8.9 to Aria 11 TMS. Parameters were compared for 358 treatment plans in 89 minutes. This direct comparison of all plan parameters in the migrated TMS against the previous TMS surpasses current QA methods that relied on repeating pretreatment QA measurements or labor-intensive and fallible hand comparisons.

  19. The morbidity and mortality outcomes of indigenous Australian peoples after isolated coronary artery bypass graft surgery: the influence of geographic remoteness.

    Science.gov (United States)

    Prabhu, Anil; Tully, Phillip J; Bennetts, Jayme S; Tuble, Sigrid C; Baker, Robert A

    2013-08-01

    Though Indigenous Australian peoples reportedly have poorer survival outcome after cardiac surgery, few studies have jointly documented the experience of major morbidity, and considered the influence of patient geographic remoteness. From January 1998 to September 2008, major morbidity events and survival were recorded for 2748 consecutive patients undergoing coronary artery bypass graft surgery. Morbidity and survival analyses adjusted for propensity deciles based on patient ethnicity and age, sex, left ventricular ejection fraction, recent myocardial infarction, tobacco smoking, diabetes, renal disease and history of stroke. Sensitivity analyses controlled for the patient accessibility/remoteness index of Australia (ARIA). The 297 Indigenous Australian patients (10.8% of total) had greater odds for total morbidity (adjusted odds ratio = 1.55; 95% confidence interval [CI] 1.04-2.30) and prolonged ventilation (adjusted odds ratio = 2.08; 95% confidence interval [CI] 1.25-3.44) in analyses adjusted for propensity deciles and geographic remoteness. With a median follow-up of 7.5 years (interquartile range 5.2-10.2), Indigenous Australian patients were found to experience 30% greater mortality risk (unadjusted hazard ratio = 1.30; 95% CI: 1.03-1.64, p = 0.03). The effect size strengthened after adjustment for propensity score (adjusted hazard ratio = 1.49; 95% CI: 1.13-1.96, p = .004). Adjustment for ARIA categorisation strengthened the effect size (adjusted HR = 1.54 (95% CI: 1.11-2.13, p = .009). Indigenous Australian peoples were at greater risk for prolonged ventilation and combined morbidity outcome, and experienced poorer survival in the longer term. Higher mortality risk among Indigenous Australians was evident even after controlling for remoteness and accessibility to services. Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

  20. MO-F-CAMPUS-T-05: SQL Database Queries to Determine Treatment Planning Resource Usage

    International Nuclear Information System (INIS)

    Fox, C; Gladstone, D

    2015-01-01

    Purpose: A radiation oncology clinic’s treatment capacity is traditionally thought to be limited by the number of machines in the clinic. As the number of fractions per course decrease and the number of adaptive plans increase, the question of how many treatment plans a clinic can plan becomes increasingly important. This work seeks to lay the ground work for assessing treatment planning resource usage. Methods: Care path templates were created using the Aria 11 care path interface. Care path tasks included key steps in the treatment planning process from the completion of CT simulation through the first radiation treatment. SQL Server Management Studio was used to run SQL queries to extract task completion time stamps along with care path template information and diagnosis codes from the Aria database. 6 months of planning cycles were evaluated. Elapsed time was evaluated in terms of work hours within Monday – Friday, 7am to 5pm. Results: For the 195 validated treatment planning cycles, the average time for planning and MD review was 22.8 hours. Of those cases 33 were categorized as urgent. The average planning time for urgent plans was 5 hours. A strong correlation between diagnosis code and range of elapsed planning time was as well as between elapsed time and select diagnosis codes was observed. It was also observed that tasks were more likely to be completed on the date due than the time that they were due. Follow-up confirmed that most users did not look at the due time. Conclusion: Evaluation of elapsed planning time and other tasks suggest that care paths should be adjusted to allow for different contouring and planning times for certain diagnosis codes and urgent cases. Additional clinic training around task due times vs dates or a structuring of care paths around due dates is also needed

  1. MO-F-CAMPUS-T-05: SQL Database Queries to Determine Treatment Planning Resource Usage

    Energy Technology Data Exchange (ETDEWEB)

    Fox, C; Gladstone, D [Dartmouth Hitchcock-Medical Center, Hanover, NH (United States)

    2015-06-15

    Purpose: A radiation oncology clinic’s treatment capacity is traditionally thought to be limited by the number of machines in the clinic. As the number of fractions per course decrease and the number of adaptive plans increase, the question of how many treatment plans a clinic can plan becomes increasingly important. This work seeks to lay the ground work for assessing treatment planning resource usage. Methods: Care path templates were created using the Aria 11 care path interface. Care path tasks included key steps in the treatment planning process from the completion of CT simulation through the first radiation treatment. SQL Server Management Studio was used to run SQL queries to extract task completion time stamps along with care path template information and diagnosis codes from the Aria database. 6 months of planning cycles were evaluated. Elapsed time was evaluated in terms of work hours within Monday – Friday, 7am to 5pm. Results: For the 195 validated treatment planning cycles, the average time for planning and MD review was 22.8 hours. Of those cases 33 were categorized as urgent. The average planning time for urgent plans was 5 hours. A strong correlation between diagnosis code and range of elapsed planning time was as well as between elapsed time and select diagnosis codes was observed. It was also observed that tasks were more likely to be completed on the date due than the time that they were due. Follow-up confirmed that most users did not look at the due time. Conclusion: Evaluation of elapsed planning time and other tasks suggest that care paths should be adjusted to allow for different contouring and planning times for certain diagnosis codes and urgent cases. Additional clinic training around task due times vs dates or a structuring of care paths around due dates is also needed.

  2. Specific features of the recent accumulation of 137Cs in tree roots of forest ecosystems within the zone of radioactive contamination

    Science.gov (United States)

    Shcheglov, Alexey; Tsvetnova, Ol'ga; Klyashtorin, Alexey; Popova, Evgenia

    2015-04-01

    Despite numerous studies of the accumulation of technogenic radionuclides in the root systems, no clear regularities of this process have been established. The tendencies found in the works of Russian and foreign researchers are rather discrepant. Some authors argue that the accumulation of radionuclides in the roots is more pronounced than that in the aboveground parts of the plants (Skovorodnikova, 2005; Romantseva, 2012; Sennerby et al., 1994; Mamikhin, 2002; Fircks et al., 2002}. Other works attest to a higher accumulation of radionuclides in the aboveground pars (Juznic et al., 1990; Chibowski, 2000; Zhianski et al., 2005), which is also typical of the stable isotopes of these elements, including 133Cs (Dong Jin Kang, YongJin Seo, Tsukasa Saito et al,2012). It is also stated that the accumulation of radionuclides in the aboveground and underground parts of plants may differ in dependence on the soil-ecological conditions and other factors (Kozhakhanov et al., 2011; Grabovskyi et al., 2013). The aim of our study was to evaluate the accumulation of 137Cs in the root systems of arboreal plants in forest ecosystems within the near zone of the Chernobyl fallout on the plots with similar soil and phytocenotic features. Pine and birch stands were studied within the 30-km-wide exclusion zone of the Chernobyl Nuclear Power Station in Ukraine in 1992-1993, when the density of the radioactive contamination of the upper (0-20 cm) layer with 137Cs reached 2153.8 kBq/m2), and in Bryansk oblast of Russia in 2013-2014, when the density of contamination varied from 1458.4 kBq/m2 (pine stand) to 2578.3 kBq/m2 (birch stand). The tree layer in these ecosystems was dominated by Pinus sylvestris (L.) and Betula pendula (Roth.), respectively. Quercus robur (L.), Picea abies (L.), and Sorbus aucuparia (L.) were also present. The specific activity of 137Cs was measured in the samples from the aboveground parts of model trees and their roots differentiated by size (0-3, 3-10, 10

  3. Diversity and primary productivity of hill beech forests from Doftana Valley (Romanian Subcarpathians

    Directory of Open Access Journals (Sweden)

    Mihaela Paucã-Comãnescu

    2009-11-01

    Full Text Available The hill beech forests cover most of the woody area in the Doftana Valley. The present study refers, for the first time, to two beech forests typical to this belt, which belong to the phytocoenological associations Epipactieto-Fagetum (Resmeritã,1972, in the Lunca Mare area, and Hieracio rotundati-Fagetum (Vida 1983, Täuber 1987 in the Sotrile area, from floristic, structural, biomass and necromassaccumulation point of view, within the framework of the vertical structure of biocoenosis.The limestone substratum, occasionally with small outcrops in the first beech forest, differs chiefly through the pH levels (6.34-5.67 from the siliceous substratum (pH 5.11-4.36 in the second beech forest. The layer of trees is dominated by Fagus sylvatica in both forests; this species is associated with Cerasus avium (4.5%,Acer pseudoplatanus (2% and Sorbus torminalis (2% in the first beech forest, and is monodominant in the second. Although the forest underwent selective cuts, more intense in the Lunca Mare area, the aboveground ligneous biomass reaches nowadays 222 t/ha in the Lunca Mare area compared to only 163 t/ha in the Sotrile area; theaverage height is 28.8±2.49 m and 23.7±1.12 m, respectively, and the diameter is 33.30±7.9 cm and 31.60±6.28 cm, respectively. The species of macrofungi, not very numerous during the study because of scarce precipitations (6 and 7 species, respectively,are predominant on the rhytidoma trees in the beech forest rooted on the limestone ground; in the Sotrile beech forest they are joined by mycorrhizal and parasite species. The layer of shrub is underdeveloped. The herbaceous layer is discontinuous, and includes, along herbs, small plants and saplings belonging to the ligneous species and to liana Hedera helix. The maximal value of the aboveground biomass of thelayer is 317 kg/ha DM in the Lunca Mare area and 235 kg /ha DM in the Sotrile area.Bryophyta is present in large quantities, especially in the ªotrile area

  4. Diversity and primary productivity of hill beech forests from Doftana Valley (Romanian Subcarpathians

    Directory of Open Access Journals (Sweden)

    Mihaela Paucã-Comãnescu

    2009-12-01

    Full Text Available The hill beech forests cover most of the woody area in the Doftana Valley. The present study refers, for the first time, to two beech forests typical to this belt, which belong to the phytocoenological associations Epipactieto-Fagetum (Resmeriţă, 1972, in the Lunca Mare area, and Hieracio rotundati-Fagetum (Vida 1983, Täuber 1987 in the Sotrile area, from floristic, structural, biomass and necromass accumulation point of view, within the framework of the vertical structure of biocoenosis. The limestone substratum, occasionally with small outcrops in the first beech forest, differs chiefly through the pH levels (6.34-5.67 from the siliceous substratum (pH 5.11-4.36 in the second beech forest. The layer of trees is dominated by Fagus sylvatica in both forests; this species is associated with Cerasus avium (4.5%, Acer pseudoplatanus (2% and Sorbus torminalis (2% in the first beech forest, and is monodominant in the second. Although the forest underwent selective cuts, more intense in the Lunca Mare area, the aboveground ligneous biomass reaches nowadays 222 t/ha in the Lunca Mare area compared to only 163 t/ha in the Sotrile area; the average height is 28.8ą2.49 m and 23.7ą1.12 m, respectively, and the diameter is 33.30ą7.9 cm and 31.60ą6.28 cm, respectively. The species of macrofungi, not very numerous during the study because of scarce precipitations (6 and 7 species, respectively, are predominant on the rhytidoma trees in the beech forest rooted on the limestone ground; in the Sotrile beech forest they are joined by mycorrhizal and parasite species. The layer of shrub is underdeveloped. The herbaceous layer is discontinuous, and includes, along herbs, small plants and saplings belonging to the ligneous species and to liana Hedera helix. The maximal value of the aboveground biomass of the layer is 317 kg/ha DM in the Lunca Mare area and 235 kg /ha DM in the Sotrile area. Bryophyta is present in large quantities, especially in the Sotrile

  5. Del libro de las polémicas: La bardolatría, el caracol y los cangrejos: una polémica sobre la poesía de Guillermo Valencia. Una polémica sobre la poesía de Guillermo Valencia

    Directory of Open Access Journals (Sweden)

    Vicente Pérez Silva

    1980-06-01

    Full Text Available A las plumas de Lope de Azuero y Bernardo Arias Trujillo se agrega ahora la de Eduardo Carranza, entusiasta animador y destacado exponente del grupo de poetas denominado Piedra y Cielo, y "uno de los temperamentos más poéticos que ha tenido nuestro país", al decir atinado de Andrés Holguín. Carranza, dueño de una extraordinaria capacidad para el canto -son múltiples sus creaciones poéticas- también arremetió contr a el maestro Guillermo Valencia, considerado por la mayoría del pueblo culto de Colombia como "el máximo poeta de la patria".

  6. Il GEOatleta moderno

    Directory of Open Access Journals (Sweden)

    Francesco Bartoli

    2006-12-01

    di tali apparecchiature può inserirsi all'interno di target quali l'intrattenimento e le attività ricreative? Negli ultimi anni stiamo riscoprendo la bellezza della natura e il piacere di dedicarci ad una serie di attività sportive outdoor che ci conciliano con essa, unendo ai benefici della mente quelli del corpo derivanti da una corretta sollecitazione della propria frequenza cardiaca. Questa mia relazione vuole essere un diario di viaggio nelle quotidiane attività all'aria aperta di un atleta non professionista, praticate durante le quattro stagioni sfruttando le tecnologie legate alla triangolazione satellitare.

  7. Tendances Carbone no. 94. SUMO policies: smart monetary policies aimed at giving a boost to green investments

    International Nuclear Information System (INIS)

    Ferron, Camille; Morel, Romain

    2014-09-01

    Among the publications of CDC Climat Research, 'Tendances Carbone' bulletin specifically studies the developments of the European market for CO 2 allowances. Beside some statistical figures about energy production/consumption and carbon markets, this issue specifically addresses the following points: - New EU Commissioner: Miguel Arias Canete (Spain) has been appointed as the new energy and climate commissioner. - EU ETS Reform: Denmark, Latvia, Slovenia, and Sweden support Germany's proposal for the mechanism becoming operational ahead of schedule as from 2017. - Climate and Energy package 2030: the European Commission has published a new proposal at the end of July with the goal of improving energy efficiency by 30% in 2030

  8. The Hispanic Monarchy in the Era of the Holy Spirit: the Atrium of Valadés

    Directory of Open Access Journals (Sweden)

    Guillermo Serés

    2017-11-01

    Full Text Available The autghor of this article analyse the influence of the work of the Millenarian Joaquin Da Fiore, Ramon Llull and Arias Montano on the composition of Christian Rhetoric by Diego Valadés. From the first of these writers, the author takes the notion of the era of the Holy Spirit; from the second, the concept of the Earthly City, for conquering the Indians; from the third, an idea for an engraving of significance in Valadés’ book, namely, the convent atrium. Additionally, he also take into account the idea of restitutio and reductio ad unum, with which both the mission of his Franciscan order and that of the Spanish monarchy are justified.

  9. Air pollution abatement by road traffic and social acceptability. A case study; Misure anti-inquinamento da traffico urbano e partecipazione del cittadino: uno studio del caso

    Energy Technology Data Exchange (ETDEWEB)

    Giuntarelli, P; Borrelli, G; Brini, S [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente

    1999-07-01

    The paper describes the research, realised via a questionnaire on citizens representative of two roman districts, analyses the social acceptability degree of actions for reducing atmospheric pollution produced by automobile traffic in the city of Rome (Italy). [Italian] Il rapporto descrive una ricerca sul campo, svolta tramite questionario e su un campione di cittadini di due quartieri di Roma, che si propone di esaminare il grado di accettazione sociale di una serie di misure tendenti a ridurre l'inquinamento atmosferico causato dal traffico veicolare urbano, dal momento che trova unanime consenso riconoscere al traffico veicolare e piu' in generale al sistema di vita urbano le maggiori responsabilita' per quanto riguarda la produzione di sostanze inquinanti nell'aria.

  10. !Atención! Tenga precaución con alguien que haya sufrido una conmoción cerebral

    Centers for Disease Control (CDC) Podcasts

    2007-11-01

    Todos los años, en los Estados Unidos se registran hasta 3.8 millones de casos de conmoción cerebral en actividades deportivas o recreativas. Este Podcast es una entrevista por radio con la Dra. Ileana Arias sobre la iniciativa titulada "Atención: conmoción cerebral en el deporte juvenil" de CDC que ofrece información a los entrenadores, los padres y los atletas sobre prevención, reconocimiento y reacción frente a una conmoción.  Created: 11/1/2007 by National Center for Injury Prevention and Controll (NCIPC).   Date Released: 11/1/2007.

  11. Air pollution abatement by road traffic and social acceptability. A case study; Misure anti-inquinamento da traffico urbano e partecipazione del cittadino: uno studio del caso

    Energy Technology Data Exchange (ETDEWEB)

    Giuntarelli, P.; Borrelli, G.; Brini, S. [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente

    1999-07-01

    The paper describes the research, realised via a questionnaire on citizens representative of two roman districts, analyses the social acceptability degree of actions for reducing atmospheric pollution produced by automobile traffic in the city of Rome (Italy). [Italian] Il rapporto descrive una ricerca sul campo, svolta tramite questionario e su un campione di cittadini di due quartieri di Roma, che si propone di esaminare il grado di accettazione sociale di una serie di misure tendenti a ridurre l'inquinamento atmosferico causato dal traffico veicolare urbano, dal momento che trova unanime consenso riconoscere al traffico veicolare e piu' in generale al sistema di vita urbano le maggiori responsabilita' per quanto riguarda la produzione di sostanze inquinanti nell'aria.

  12. Tendances Carbone no. 95. Feedback from the New York Climate Summit: a CO2 price is necessary, but not sufficient

    International Nuclear Information System (INIS)

    Alberola, Emilie; Leguet, Benoit; Morel, Romain

    2014-10-01

    Among the publications of CDC Climat Research, 'Tendances Carbone' bulletin specifically studies the developments of the European market for CO 2 allowances. Beside some statistical figures about energy production/consumption and carbon markets, this issue specifically addresses the following points: - New EU Energy and Climate Action Commissioner: the Miguel Arias Canete's nomination was approved by a majority of Members of EU Parliament. - EU ETS - MSR timetable: On September 23, the timetable was announced; deadline for amendments is 11 December 2014; ENVI committee votes on 23 or 24 February 2015. - BKM Summit: On September 23, the European Commission President, Jose Manuel Barroso stated that 20% of the EU budget for 2014-2020 (euro 180 billion) will be spent on climate action

  13. MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis) : the new generation guideline implementation

    NARCIS (Netherlands)

    Bousquet, J.; Schunemann, H. J.; Fonseca, J.; Samolinski, B.; Bachert, C.; Canonica, G. W.; Casale, T.; Cruz, A. A.; Demoly, P.; Hellings, P.; Valiulis, A.; Wickman, M.; Zuberbier, T.; Bosnic-Anticevitch, S.; Bedbrook, A.; Bergmann, K. C.; Caimmi, D.; Dahl, R.; Fokkens, W. J.; Grisle, I.; Lodrup Carlsen, K.; Mullol, J.; Muraro, A.; Palkonen, S.; Papadopoulos, N.; Passalacqua, G.; Ryan, D.; Valovirta, E.; Yorgancioglu, A.; Aberer, W.; Agache, I.; Adachi, M.; Akdis, C. A.; Akdis, M.; Annesi-Maesano, I.; Ansotegui, I. J.; Anto, J. M.; Arnavielhe, S.; Arshad, H.; Baiardini, I.; Baigenzhin, A. K.; Barbara, C.; Bateman, E. D.; Beghe, B.; Bel, E. H.; Ben Kheder, A.; Bennoor, K. S.; Benson, M.; Bewick, M.; Bieber, T.; Bindslev-Jensen, C.; Bjermer, L.; Blain, H.; Boner, A. L.; Boulet, L. P.; Bonini, M.; Bonini, S.; Bosse, I.; Bourret, R.; Bousquet, P. J.; Braido, F.; Briggs, A. H.; Brightling, C. E.; Brozek, J.; Buhl, R.; Burney, P. G.; Bush, A.; Caballero-Fonseca, F.; Calderon, M. A.; Camargos, P. A. M.; Camuzat, T.; Carlsen, K. H.; Carr, W.; Sarabia, A. M. Cepeda; Chavannes, N. H.; Chatzi, L.; Chen, Y. Z.; Chiron, R.; Chkhartishvili, E.; Chuchalin, A. G.; Ciprandi, G.; Cirule, I.; Correia de Sousa, J.; Cox, L.; Crooks, G.; Costa, D. J.; Custovic, A.; Dahlen, S. E.; Darsow, U.; De Carlo, G.; De Blay, F.; Dedeu, T.; Deleanu, D.; Denburg, J. A.; Devillier, P.; Didier, A.; Dinh-Xuan, A. T.; Dokic, D.; Douagui, H.; Dray, G.; Dubakiene, R.; Durham, S. R.; Dykewicz, M. S.; El-Gamal, Y.; Emuzyte, R.; Wagner, A. Fink; Fletcher, M.; Fiocchi, A.; Forastiere, F.; Gamkrelidze, A.; Gemicioglu, B.; Gereda, J. E.; Gonzalez Diaz, S.; Gotua, M.; Grouse, L.; Guzman, M. A.; Haahtela, T.; Hellquist-Dahl, B.; Heinrich, J.; Horak, F.; Hourihane, J. O. B.; Howarth, P.; Humbert, M.; Hyland, M. E.; Ivancevich, J. C.; Jares, E. J.; Johnston, S. L.; Joos, G.; Jonquet, O.; Jung, K. S.; Just, J.; Kaidashev, I.; Kalayci, O.; Kalyoncu, A. F.; Keil, T.; Keith, P. K.; Khaltaev, N.; Klimek, L.; N'Goran, B. Koffi; Kolek, V.; Koppelman, G. H.; Kowalski, M. L.; Kull, I.; Kuna, P.; Kvedariene, V.; Lambrecht, B.; Lau, S.; Larenas-Linnemann, D.; Laune, D.; Le, L. T. T.; Lieberman, P.; Lipworth, B.; Li, J.; Louis, R.; Magard, Y.; Magnan, A.; Mahboub, B.; Majer, I.; Makela, M. J.; Manning, P.; De Manuel Keenoy, E.; Marshall, G. D.; Masjedi, M. R.; Maurer, M.; Mavale-Manuel, S.; Melen, E.; Melo-Gomes, E.; Meltzer, E. O.; Merk, H.; Miculinic, N.; Mihaltan, F.; Milenkovic, B.; Mohammad, Y.; Molimard, M.; Momas, I.; Montilla-Santana, A.; Morais-Almeida, M.; Moesges, R.; Namazova-Baranova, L.; Naclerio, R.; Neou, A.; Neffen, H.; Nekam, K.; Niggemann, B.; Nyembue, T. D.; O'Hehir, R. E.; Ohta, K.; Okamoto, Y.; Okubo, K.; Ouedraogo, S.; Paggiaro, P.; Pali-Schoell, I.; Palmer, S.; Panzner, P.; Papi, A.; Park, H. S.; Pavord, I.; Pawankar, R.; Pfaar, O.; Picard, R.; Pigearias, B.; Pin, I.; Plavec, D.; Pohl, W.; Popov, T. A.; Portejoie, F.; Postma, D.; Potter, P.; Price, D.; Rabe, K. F.; Raciborski, F.; Pontal, F. Radier; Repka-Ramirez, S.; Robalo-Cordeiro, C.; Rolland, C.; Rosado-Pinto, J.; Reitamo, S.; Rodenas, F.; Roman Rodriguez, M.; Romano, A.; Rosario, N.; Rosenwasser, L.; Rottem, M.; Sanchez-Borges, M.; Scadding, G. K.; Serrano, E.; Schmid-Grendelmeier, P.; Sheikh, A.; Simons, F. E. R.; Sisul, J. C.; Skrindo, I.; Smit, H. A.; Sole, D.; Sooronbaev, T.; Spranger, O.; Stelmach, R.; Strandberg, T.; Sunyer, J.; Thijs, C.; Todo-Bom, A.; Triggiani, M.; Valenta, R.; Valero, A. L.; van Hage, M.; Vandenplas, O.; Vezzani, G.; Vichyanond, P.; Viegi, G.; Wagenmann, M.; Walker, S.; Wang, D. Y.; Wahn, U.; Williams, D. M.; Wright, J.; Yawn, B. P.; Yiallouros, P. K.; Yusuf, O. M.; Zar, H. J.; Zernotti, M. E.; Zhang, L.; Zhong, N.; Zidarn, M.; Mercier, J.

    2015-01-01

    Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient

  14. MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

    NARCIS (Netherlands)

    Bousquet, J.; Schunemann, H. J.; Fonseca, J.; Samolinski, B.; Bachert, C.; Canonica, G. W.; Casale, T.; Cruz, A. A.; Demoly, P.; Hellings, P.; Valiulis, A.; Wickman, M.; Zuberbier, T.; Bosnic-Anticevitch, S.; Bedbrook, A.; Bergmann, K. C.; Caimmi, D.; Dahl, R.; Fokkens, W. J.; Grisle, I.; Lodrup Carlsen, K.; Mullol, J.; Muraro, A.; Palkonen, S.; Papadopoulos, N.; Passalacqua, G.; Ryan, D.; Valovirta, E.; Yorgancioglu, A.; Aberer, W.; Agache, I.; Adachi, M.; Akdis, C. A.; Akdis, M.; Annesi-Maesano, I.; Ansotegui, I. J.; Anto, J. M.; Arnavielhe, S.; Arshad, H.; Baiardini, I.; Baigenzhin, A. K.; Barbara, C.; Bateman, E. D.; Beghé, B.; Bel, E. H.; Ben Kheder, A.; Bennoor, K. S.; Benson, M.; Bewick, M.; Bieber, T.; Bindslev-Jensen, C.; Bjermer, L.; Blain, H.; Boner, A. L.; Boulet, L. P.; Bonini, M.; Bonini, S.; Bosse, I.; Bourret, R.; Bousquet, P. J.; Braido, F.; Briggs, A. H.; Brightling, C. E.; Brozek, J.; Buhl, R.; Burney, P. G.; Bush, A.; Caballero-Fonseca, F.; Calderon, M. A.; Camargos, P. A. M.; Camuzat, T.; Carlsen, K. H.; Carr, W.; Cepeda Sarabia, A. M.; Chavannes, N. H.; Chatzi, L.; Chen, Y. Z.; Chiron, R.; Chkhartishvili, E.; Chuchalin, A. G.; Ciprandi, G.; Cirule, I.; Correia de Sousa, J.; Cox, L.; Crooks, G.; Costa, D. J.; Custovic, A.; Dahlen, S. E.; Darsow, U.; de Carlo, G.; de Blay, F.; Dedeu, T.; Deleanu, D.; Denburg, J. A.; Devillier, P.; Didier, A.; Dinh-Xuan, A. T.; Dokic, D.; Douagui, H.; Dray, G.; Dubakiene, R.; Durham, S. R.; Dykewicz, M. S.; El-Gamal, Y.; Emuzyte, R.; Fink Wagner, A.; Fletcher, M.; Fiocchi, A.; Forastiere, F.; Gamkrelidze, A.; Gemicioğlu, B.; Gereda, J. E.; González Diaz, S.; Gotua, M.; Grouse, L.; Guzmán, M. A.; Haahtela, T.; Hellquist-Dahl, B.; Heinrich, J.; Horak, F.; Hourihane, J. O. 'b; Howarth, P.; Humbert, M.; Hyland, M. E.; Ivancevich, J. C.; Jares, E. J.; Johnston, S. L.; Joos, G.; Jonquet, O.; Jung, K. S.; Just, J.; Kaidashev, I.; Kalayci, O.; Kalyoncu, A. F.; Keil, T.; Keith, P. K.; Khaltaev, N.; Klimek, L.; Koffi N'goran, B.; Kolek, V.; Koppelman, G. H.; Kowalski, M. L.; Kull, I.; Kuna, P.; Kvedariene, V.; Lambrecht, B.; Lau, S.; Larenas-Linnemann, D.; Laune, D.; Le, L. T. T.; Lieberman, P.; Lipworth, B.; Li, J.; Louis, R.; Magard, Y.; Magnan, A.; Mahboub, B.; Majer, I.; Makela, M. J.; Manning, P.; de Manuel Keenoy, E.; Marshall, G. D.; Masjedi, M. R.; Maurer, M.; Mavale-Manuel, S.; Melén, E.; Melo-Gomes, E.; Meltzer, E. O.; Merk, H.; Miculinic, N.; Mihaltan, F.; Milenkovic, B.; Mohammad, Y.; Molimard, M.; Momas, I.; Montilla-Santana, A.; Morais-Almeida, M.; Mösges, R.; Namazova-Baranova, L.; Naclerio, R.; Neou, A.; Neffen, H.; Nekam, K.; Niggemann, B.; Nyembue, T. D.; O'Hehir, R. E.; Ohta, K.; Okamoto, Y.; Okubo, K.; Ouedraogo, S.; Paggiaro, P.; Pali-Schöll, I.; Palmer, S.; Panzner, P.; Papi, A.; Park, H. S.; Pavord, I.; Pawankar, R.; Pfaar, O.; Picard, R.; Pigearias, B.; Pin, I.; Plavec, D.; Pohl, W.; Popov, T. A.; Portejoie, F.; Postma, D.; Potter, P.; Price, D.; Rabe, K. F.; Raciborski, F.; Radier Pontal, F.; Repka-Ramirez, S.; Robalo-Cordeiro, C.; Rolland, C.; Rosado-Pinto, J.; Reitamo, S.; Rodenas, F.; Roman Rodriguez, M.; Romano, A.; Rosario, N.; Rosenwasser, L.; Rottem, M.; Sanchez-Borges, M.; Scadding, G. K.; Serrano, E.; Schmid-Grendelmeier, P.; Sheikh, A.; Simons, F. E. R.; Sisul, J. C.; Skrindo, I.; Smit, H. A.; Solé, D.; Sooronbaev, T.; Spranger, O.; Stelmach, R.; Strandberg, T.; Sunyer, J.; Thijs, C.; Todo-Bom, A.; Triggiani, M.; Valenta, R.; Valero, A. L.; van Hage, M.; Vandenplas, O.; Vezzani, G.; Vichyanond, P.; Viegi, G.; Wagenmann, M.; Walker, S.; Wang, D. Y.; Wahn, U.; Williams, D. M.; Wright, J.; Yawn, B. P.; Yiallouros, P. K.; Yusuf, O. M.; Zar, H. J.; Zernotti, M. E.; Zhang, L.; Zhong, N.; Zidarn, M.; Mercier, J.

    2015-01-01

    Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient

  15. Dynamics of game from 65 Giera aria Forest District Lunca Timisului in 2009-2013 period

    Directory of Open Access Journals (Sweden)

    Dorel Dronca

    2014-10-01

    Full Text Available Integration of the Romania in the E.U., is imposing a special attention to game populations. The aim of the present paper was to study the quantitative evolution of the game for the 13 species during 2009-2013, on the hunting terrain 65 Giera, from Forest Domain – Lunca Timişului, with a total surface of 11,974 ha. The study shows that form the 13 species monitored, 3 were not identified on this hunting terrain Red Deer (Cervus elaphus L., Fallow Deer (Dama dama L, European Pine Marten (Martes martes L.. For the other species identified the population evolution in number demonstrated that there is a god correlation between the number of individuals and its biogenic capacity. We recommend careful monitoring of the natural selection and the efficient use of artificial breeding especially for the European hare (Lepus europaeus P. specie.

  16. Adventures in Music Translation: Italian Songs and Arias (aka “The Yellow Book” and Me

    Directory of Open Access Journals (Sweden)

    Lynn Penrod

    2017-06-01

    Full Text Available This article is a general exploration of translation issues involved in the translation and performance of the art song, arguing that although critical interest in recent years has been growing, the problems involved in these hybrid translation projects involving both text and music present a number of conundrums: primacy of text or music, focus on performability, and age-old arguments about fidelity and/or foreignization vs domestication. Using information from theatre translation and input from singers themselves, the author argues that this particular area of translation studies will work best in the future with a collaborative approach that includes translators, musicologists, and performers working together in order to produce the most “singable” text as possible for the art song in performance.

  17. Air pollution biomonitoring using terrestrial mosses; Il biomonitoraggio di pollutanti nell`aria mediante i muschi

    Energy Technology Data Exchange (ETDEWEB)

    Cenci, R. M. [C.C.R. Ispra, Istituto dell`Ambiente, La Spezia (Italy); Palmieri, F.; Mousty, F. [U.S.L. n.5, La Spezia (Italy)

    1998-06-01

    The spatial-temporal concentration of elements harmful for life has been investigated using terrestrial mosses of the Hypnum cupressiforme species. The results obtained have been implemented with elements of soil collected in the same area, for a wider information. Concerning the mosses, the investigated elements are: Al, As, Cd, Co, Cr, Fe, Mn, Pb, Cu, Ti, V, and Zn. The elements investigated on soil samples, collected only once, are: As, Cd, Cr, Mn, Ni, Cu and Pb. The results obtained allowed to identify an area of about 100 Kmq, located North-West with regard to La Spezia city (Italy), where the concentrations are higher than the remaining area. In the smaller investigation area, a surface of 0,12 kmq was found where the fall out rate for Pb is 0,21 g m-2 y-1, a value three times greater than the maximal european value tested in Rumania area (Ruehling, 1994). Mosses, which are highly efficient indicators of atmospheric pollution, have permitted to identify anthropogenic polluted areas and to evaluate the fall out rate. [Italiano] Mediante l`utilizzo del muschio appartenente alla specie Hypnum cupressiforme e` stata valutata la distribuzione nello spazio e nel tempo della concentrazione di elementi dannosi per la salute dell`uomo. I dati raccolti sono stati ampliati analizzando campioni di suolo raccolti nelle medesime localita`. Complessivamente sono state approntate 32 stazioni. Dopo il posizionamento i talli di muschio venivano raccolti per tre volte con cadenza quadrimestrale. per quanto riguarda i muschi sono state integrate le concentrazioni dei seguenti elementi: Al, As, Cd, Co, Cr, Fe, Mn, Pb, Cu, Ti, V, e Zn. Nei suoli, raccolti una sola volta, l`elenco degli elementi e` stato il seguente: As, Cd, Cr, Mn, Ni, Cu e Pb. I risultati ottenuti hanno permesso l`identificazione di un`area di circa 100 kmq posta a Nord-Ovest della citta` di La Spezia, dove le concentrazioni di As, Co, Ni, Cu, Ti e V sono superiori rispetto alla restante area. Nella piccola area indagata si e` potuto identificare una superficie pari a 0,12 kmq nella quale il rateo did eposizione per l`elemento piombo e` risultato pari a 0,21 g m-2 anno-1, valore tre volte superiore ai valori massimi europei riscontrati in alcune aree della Romania (Ruehling, 1994). l`elevata efficienza dei muschi quali indicatori dell`inquinamento atmosferico ha permesso l`identificazione di quelle aree soggette ad una maggior pressione antropica e di valutare il rateo annuo di deposizione.

  18. MO-G-BRE-05: Clinical Process Improvement and Billing in Radiation Oncology: A Case Study of Applying FMEA for CPT Code 77336 (continuing Medical Physics Consultation)

    International Nuclear Information System (INIS)

    Spirydovich, S; Huq, M

    2014-01-01

    Purpose: The improvement of quality in healthcare can be assessed by Failure Mode and Effects Analysis (FMEA). In radiation oncology, FMEA, as applied to the billing CPT code 77336, can improve both charge capture and, most importantly, quality of the performed services. Methods: We created an FMEA table for the process performed under CPT code 77336. For a given process step, each member of the assembled team (physicist, dosimetrist, and therapist) independently assigned numerical values for: probability of occurrence (O, 1–10), severity (S, 1–10), and probability of detection (D, 1–10) for every failure mode cause and effect combination. The risk priority number, RPN, was then calculated as a product of O, S and D from which an average RPN was calculated for each combination mentioned above. A fault tree diagram, with each process sorted into 6 categories, was created with linked RPN. For processes with high RPN recommended actions were assigned. 2 separate R and V systems (Lantis and EMR-based ARIA) were considered. Results: We identified 9 potential failure modes and corresponding 19 potential causes of these failure modes all resulting in unjustified 77336 charge and compromised quality of care. In Lantis, the range of RPN was 24.5–110.8, and of S values – 2–10. The highest ranking RPN of 110.8 came from the failure mode described as “end-of-treatment check not done before the completion of treatment”, and the highest S value of 10 (RPN=105) from “overrides not checked”. For the same failure modes, within ARIA electronic environment with its additional controls, RPN values were significantly lower (44.3 for end-of-treatment missing check and 20.0 for overrides not checked). Conclusion: Our work has shown that when charge capture was missed that also resulted in some services not being performed. Absence of such necessary services may result in sub-optimal quality of care rendered to patients

  19. Valutazione degli elementi di struttura e monitoraggio microbiologico nel Comparto operatorio comune del Dipartimento ortopedico dell'Azienda ospedaliera di Parma

    Directory of Open Access Journals (Sweden)

    C. Pasquarella

    2003-05-01

    Full Text Available Obiettivi: scopo di questo studio, che si inserisce nell’ambito di un progetto multicentrico promosso dal Gruppo Italiano Studio Igiene Ospedaliera, è stato quello di valutare le condizioni ambientali e gestionali delle sale operatorie del comparto ortopedico dell’Azienda ospedaliera di Parma. Metodi: l’indagine, svolta nell’ottobre 2002, ha previsto la compilazione di un questionario, riguardante gli aspetti strutturali, impiantistici, organizzativi e gestionali, e l’effettuazione di un monitoraggio microbiologico ambientale nelle diverse aree del blocco operatorio. La carica microbica dell’aria è stata valutata utilizzando piastre di sedimentazione per la rilevazione dell’Indice Microbico Aria (IMA mentre per le superfici sono state impiegate membrane di nitrocellulosa. I campionamenti sono stati effettuati prima dell’inizio e durante l’attività chirurgica. Risultati: i dati ottenuti per mezzo del questionario hanno evidenziato condizioni generalmente buone, sia dal punto di vista strutturale che gestionale del comparto operatorio studiato. Per quanto riguarda il controllo microbiologico, nelle sale operatorie, in tutte le rilevazioni prima dell’attività si sono ottenuti valori di IMA uguali a 0; durante l’attività, si è registrato un valore massimo di IMA di 4 in quelle a flusso laminare e di 19 in quelle con flusso turbolento, al di sotto dei valori limite, rispettivamente di 5 e 25; i valori di contaminazione microbica delle superfici prima dell’attività hanno oscillato da un minimo di 0 ufc/cm2 a un massimo di 0,20 ufc/cm2; durante l’attività, solo in una rilevazione si è registrato un valore di 0,58 ufc/cm2, superiore al valore soglia stabilito. Anche negli altri ambienti del comparto operatorio la contaminazione microbica è risultata complessivamente al di sotto dei limiti di riferimento. Conclusioni: il questionario si è rivelato un valido strumento

  20. Paul E. Kahle and Federico Pérez Castro: The Origins of the Madrid School of Biblical Text Criticism

    Directory of Open Access Journals (Sweden)

    Fernández Tejero, Emilia

    2008-06-01

    Full Text Available We have frequently been asked about the origins of the Madrid School of Biblical Text Criticism. We have limited the content of this paper to Masoretic studies. Research into the files of the former Instituto Arias Montano of the CSIC disclosed a series of unedited letters between Professors Kahle and Pérez Castro; a paper by F. Pérez Castro and F. Cantera Burgos on “Prof. Paul E. Kahle y los estudios de crítica textual bíblica en España,” and a description by F. Pérez Castro of the first project to edit the Cairo Codex of the Prophets. Through these materials we can trace the main steps of the relationship between these two relevant scholars and the role that such a relationship played in the origin and late development of these studies in Madrid.

    A menudo se nos ha preguntado por los orígenes de la escuela de crítica textual bíblica de Madrid. Hemos limitado el contenido de este artículo a los estudios masoréticos. Investigando en los archivos del antiguo Instituto Arias Montano del CSIC hemos encontrado una colección de cartas inéditas entre los Profesores Kahle y Pérez Castro; un artículo escrito por F. Pérez Castro y F. Cantera Burgos titulado «Prof. Paul E. Kahle y los estudios de crítica textual bíblica en España», y la descripción hecha por Pérez Castro del primer proyecto para editar el Códice de Profetas de El Cairo. Gracias a estos testimonios hemos podido documentar las principales fases de la relación entre estos dos eminentes profesores y el papel que tal relación desempeñó en el origen y posterior desarrollo de estos estudios en Madrid.

  1. Evaluación de la eficacia in vitro e in vivo del tratamiento antimicrobiano combinado por el tablero de damas Effectiveness of a combined antimicrobial treatment by means of the draughtboard. In vitro and in vivo assessment

    Directory of Open Access Journals (Sweden)

    María Espino Hernández

    2009-08-01

    Full Text Available El presente trabajo tuvo como objetivo, evaluar la eficacia clínica del tratamiento antimicrobiano combinado mediante pruebas de sinergismo in vitro y determinar la eficacia del procedimiento empleado para orientar la aplicación de estas formas de tratamiento en el paciente con sepsis por bacterias con resistencia variada. Se evaluó el tratamiento aplicado a 163 recién nacidos con sepsis corroborada por hemocultivo positivo en el Hospital Ginecobstétrico Universitario "América Arias", durante el periodo de enero de 1993 a diciembre de 2000, por el método tablero de damas (checkerboard en placas de microtitulación. Las combinaciones de fármacos sinérgicas in vitro presentaron una alta probabilidad de eficacia clínica, independiente del patrón de susceptibilidad del microorganismo aun frente a cepas resistentes a los 2 antimicrobianos utilizados en el tratamiento. Todos los resultados antagónicos in vitro se correspondieron con un fallo clínico terapéutico. El procedimiento utilizado puede constituir una valiosa herramienta para orientar la terapéutica en pacientes con sepsis por microorganismos resistentes.The aim of present paper was to evaluate clinical effectiveness of combined antimicrobial treatment by means of in vitro synergism tests and to determine effectiveness of used procedure to direct applications of these treatment strategies in patient presenting with sepsis from varied resistance bacteria. Treatment applied was assessed in 163 newborn patients presenting with sepsis from positive hemoculture in "America Arias" University Gynecology-Obstetrics Hospital from January 1993 to December 2000, by checkerboard method in microtritate plates. In vitro synergic drug combinations showed a high probability of clinical effectiveness, independently of susceptibility pattern of microorganism event versus resistant strains to both antimicrobials used in treatment. All in vitro antagonistic results correspond both with a

  2. SU-E-T-502: Biometrically Accepted Patient Records

    International Nuclear Information System (INIS)

    Basavatia, A; Kalnicki, S; Garg, M; Lukaj, A; Hong, L; Fret, J; Yaparpalvi, R; Tome, W

    2014-01-01

    Purpose: To implement a clinically useful palm vein pattern recognition biometric system to treat the correct treatment plan to the correct patient each and every time and to check-in the patient into the department to access the correct medical record. Methods: A commercially available hand vein scanning system was paired to Aria and utilized an ADT interface from the hospital electronic health system. Integration at two points in Aria, version 11 MR2, first at the appointment tracker screen for the front desk medical record access and second at the queue screen on the 4D treatment console took place for patient daily time-out. A test patient was utilized to check accuracy of identification as well as to check that no unintended interactions take place between the 4D treatment console and the hand vein scanning system. This system has been in clinical use since December 2013. Results: Since implementation, 445 patients have been enrolled into our biometric system. 95% of patients learn the correct methodology of hand placement on the scanner in the first try. We have had two instances of patient not found because of a bad initial scan. We simply erased the scanned metric and the patient enrolled again in those cases. The accuracy of the match is 100% for each patient, we have not had one patient misidentified. We can state this because we still use patient photo and date of birth as identifiers. A QA test patient is run monthly to check the integrity of the system. Conclusion: By utilizing palm vein scans along with the date of birth and patient photo, another means of patient identification now exits. This work indicates the successful implementation of technology in the area of patient safety by closing the gap of treating the wrong plan to a patient in radiation oncology. FOJP Service Corporation covered some of the costs of the hardware and software of the palm vein pattern recognition biometric system

  3. WE-G-BRA-02: SafetyNet: Automating Radiotherapy QA with An Event Driven Framework

    International Nuclear Information System (INIS)

    Hadley, S; Kessler, M; Litzenberg, D; Lee, C; Irrer, J; Chen, X; Acosta, E; Weyburne, G; Lam, K; Younge, K; Matuszak, M; Keranen, W; Covington, E; Moran, J

    2015-01-01

    Purpose: Quality assurance is an essential task in radiotherapy that often requires many manual tasks. We investigate the use of an event driven framework in conjunction with software agents to automate QA and eliminate wait times. Methods: An in house developed subscription-publication service, EventNet, was added to the Aria OIS to be a message broker for critical events occurring in the OIS and software agents. Software agents operate without user intervention and perform critical QA steps. The results of the QA are documented and the resulting event is generated and passed back to EventNet. Users can subscribe to those events and receive messages based on custom filters designed to send passing or failing results to physicists or dosimetrists. Agents were developed to expedite the following QA tasks: Plan Revision, Plan 2nd Check, SRS Winston-Lutz isocenter, Treatment History Audit, Treatment Machine Configuration. Results: Plan approval in the Aria OIS was used as the event trigger for plan revision QA and Plan 2nd check agents. The agents pulled the plan data, executed the prescribed QA, stored the results and updated EventNet for publication. The Winston Lutz agent reduced QA time from 20 minutes to 4 minutes and provided a more accurate quantitative estimate of radiation isocenter. The Treatment Machine Configuration agent automatically reports any changes to the Treatment machine or HDR unit configuration. The agents are reliable, act immediately, and execute each task identically every time. Conclusion: An event driven framework has inverted the data chase in our radiotherapy QA process. Rather than have dosimetrists and physicists push data to QA software and pull results back into the OIS, the software agents perform these steps immediately upon receiving the sentinel events from EventNet. Mr Keranen is an employee of Varian Medical Systems. Dr. Moran’s institution receives research support for her effort for a linear accelerator QA project from

  4. SU-E-T-502: Biometrically Accepted Patient Records

    Energy Technology Data Exchange (ETDEWEB)

    Basavatia, A; Kalnicki, S; Garg, M; Lukaj, A; Hong, L [Montefiore Medical Center, Bronx, NY (United States); Fret, J [Montefiore Information Technology, Yonkers, NY (United States); Yaparpalvi, R [Montefiore Medical Center, Bronx, NY (United States); Montefiore Medical Center, Bronx, NY (United States); Tome, W [Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY (United States)

    2014-06-01

    Purpose: To implement a clinically useful palm vein pattern recognition biometric system to treat the correct treatment plan to the correct patient each and every time and to check-in the patient into the department to access the correct medical record. Methods: A commercially available hand vein scanning system was paired to Aria and utilized an ADT interface from the hospital electronic health system. Integration at two points in Aria, version 11 MR2, first at the appointment tracker screen for the front desk medical record access and second at the queue screen on the 4D treatment console took place for patient daily time-out. A test patient was utilized to check accuracy of identification as well as to check that no unintended interactions take place between the 4D treatment console and the hand vein scanning system. This system has been in clinical use since December 2013. Results: Since implementation, 445 patients have been enrolled into our biometric system. 95% of patients learn the correct methodology of hand placement on the scanner in the first try. We have had two instances of patient not found because of a bad initial scan. We simply erased the scanned metric and the patient enrolled again in those cases. The accuracy of the match is 100% for each patient, we have not had one patient misidentified. We can state this because we still use patient photo and date of birth as identifiers. A QA test patient is run monthly to check the integrity of the system. Conclusion: By utilizing palm vein scans along with the date of birth and patient photo, another means of patient identification now exits. This work indicates the successful implementation of technology in the area of patient safety by closing the gap of treating the wrong plan to a patient in radiation oncology. FOJP Service Corporation covered some of the costs of the hardware and software of the palm vein pattern recognition biometric system.

  5. WE-G-BRA-02: SafetyNet: Automating Radiotherapy QA with An Event Driven Framework

    Energy Technology Data Exchange (ETDEWEB)

    Hadley, S; Kessler, M [The University of Michigan, Ann Arbor, MI (United States); Litzenberg, D [Univ Michigan, Ann Arbor, MI (United States); Lee, C; Irrer, J; Chen, X; Acosta, E; Weyburne, G; Lam, K; Younge, K; Matuszak, M [University of Michigan, Ann Arbor, MI (United States); Keranen, W [Varian Medical Systems, Palo Alto, CA (United States); Covington, E [University of Michigan Hospital and Health System, Ann Arbor, MI (United States); Moran, J [Univ Michigan Medical Center, Ann Arbor, MI (United States)

    2015-06-15

    Purpose: Quality assurance is an essential task in radiotherapy that often requires many manual tasks. We investigate the use of an event driven framework in conjunction with software agents to automate QA and eliminate wait times. Methods: An in house developed subscription-publication service, EventNet, was added to the Aria OIS to be a message broker for critical events occurring in the OIS and software agents. Software agents operate without user intervention and perform critical QA steps. The results of the QA are documented and the resulting event is generated and passed back to EventNet. Users can subscribe to those events and receive messages based on custom filters designed to send passing or failing results to physicists or dosimetrists. Agents were developed to expedite the following QA tasks: Plan Revision, Plan 2nd Check, SRS Winston-Lutz isocenter, Treatment History Audit, Treatment Machine Configuration. Results: Plan approval in the Aria OIS was used as the event trigger for plan revision QA and Plan 2nd check agents. The agents pulled the plan data, executed the prescribed QA, stored the results and updated EventNet for publication. The Winston Lutz agent reduced QA time from 20 minutes to 4 minutes and provided a more accurate quantitative estimate of radiation isocenter. The Treatment Machine Configuration agent automatically reports any changes to the Treatment machine or HDR unit configuration. The agents are reliable, act immediately, and execute each task identically every time. Conclusion: An event driven framework has inverted the data chase in our radiotherapy QA process. Rather than have dosimetrists and physicists push data to QA software and pull results back into the OIS, the software agents perform these steps immediately upon receiving the sentinel events from EventNet. Mr Keranen is an employee of Varian Medical Systems. Dr. Moran’s institution receives research support for her effort for a linear accelerator QA project from

  6. Assessment of potential strong ground motions in the city of Rome

    Directory of Open Access Journals (Sweden)

    L. Malagnini

    1994-06-01

    Full Text Available A methodology is used which combines stochastic generation of random series with a finite-difference technique to estimate the expected horizontal ground motion for the city of Rome as induced by a large earthquake in the Central Apennines. In this approach, source properties and long-path propagation are modelled through observed spectra of ground motion in the region, while the effects of the near-surface geology in the city are simulated by means of a finite-difference technique applied to 2-D models including elastic and anelastic properties of geologic materials and topographic variations. The parameters commonly used for earthquake engineering purposes are estimated from the simulated time histories of horizontal ground motion. We focus our attention on peak ground acceleration and velocity, and on the integral of the squared acceleration and velocity (that are proportional to the Arias intensity and seismic energy flux, respectively. Response spectra are analyzed as well. Parameter variations along 2-D profiles visualize the effects of the small-scale geological heterogeneities and topography irregularities on ground motion in the case of a strong earthquake. Interestingly, the largest amplification of peak ground acceleration and Arias intensity does not necessarily occur at the same sites where peak ground velocity and flux of seismic energy reach their highest values, depending on the frequency band of amplification. A magnitude 7 earthquake at a distance of 100 km results in peak ground accelerations ranging from 30 to 70 gals while peak ground velocities are estimated to vary from 5 to 7 cm/s; moreover, simulated time histories of horizontal ground motion yield amplitudes of 5% damped pseudovelocity response spectra as large as 15-20 cm/s for frequencies from 1to 3 Hz. In this frequency band, the mean value is 7 cm/s for firm sites and ranges from 10 to 13 cm/s for soil sites. All these results are in good agreement with predictions

  7. SU-E-T-35: A General Fill Factor Definition Serving to Characterise the MLC Misalignment Detection Capabilities of Two-Dimensional Detector Arrays

    Energy Technology Data Exchange (ETDEWEB)

    Stelljes, T.S.; Looe, H.K.; Poppe, B. [Clinic for Radiation Therapy, Pius-Hospital, Oldenburg, DE (United States); WG Medical Radiation Physics, Carl von Ossietzky University, Oldenburg, DE (United States); Harder, D. [Prof. em., Medical Physics and Biophysics, Georg August University, Goettingen, DE (Germany)

    2015-06-15

    Purpose: To present a general definition of the fill factor realistically characterizing the “field coverage”, i.e. the MLC misalignment detection capabilities of a detector array. Methods: According to Gago-Arias et al.{sup 1} the fill factor of a 2D array is defined as the ratio of the area enclosed by the FWHM of the fluence response function KM(x) of a single detector and its cell area defined by the detector spacing. More generally - accounting also for the possible overlap between FWHM’s of neighboured detectors - the fill factor is here defined as that fraction of the sum of the detector cell areas in which a defined MLC misalignment is detectable when the induced percentage signal changes exceed a detection threshold d. Ideally the generalized fill factor may reach 100 %. With user code EGS-chamber and a 2 MeV photon slit beam 0.25 mm wide, both types of the fill factor were calculated for an array with total cell area 100 cm{sup 2} for chamber widths 1–9 mm, using =1mm, d=5%. Results: For single chamber width 5 mm, fill factors were 0.49 (FWHM) and 0.61 (generalized). For chamber width 2 mm the FWHM fill factor was 0.13 whereas the generalized fill factor was 0.32. For chamber widths above 7 mm, the FWHM fill factor exceeds unity, and the general fill factor is exactly 1.00. Conclusions: An updated fill factor definition is introduced which, as a generalization of the FWHM-based definition, more closely estimates the performance of small array chambers and gives a realistic value in the case of overlapping sensitive areas of neighboured chambers. References:{sup 1}A. Gago-Arias, L. Brualla-Gonzalez, D.M. Gonzalez-Castano, F. Gomez, M.S. Garcia, V.L. Vega, J.M. Sueiro, J. Pardo-Montero, “Evaluation of chamber response function influence on IMRT verification using 2D commercial detector arrays,” Phys. Med. Biol. 57, 2005–2020 (2012)

  8. SU-E-T-35: A General Fill Factor Definition Serving to Characterise the MLC Misalignment Detection Capabilities of Two-Dimensional Detector Arrays

    International Nuclear Information System (INIS)

    Stelljes, T.S.; Looe, H.K.; Poppe, B.; Harder, D.

    2015-01-01

    Purpose: To present a general definition of the fill factor realistically characterizing the “field coverage”, i.e. the MLC misalignment detection capabilities of a detector array. Methods: According to Gago-Arias et al. 1 the fill factor of a 2D array is defined as the ratio of the area enclosed by the FWHM of the fluence response function KM(x) of a single detector and its cell area defined by the detector spacing. More generally - accounting also for the possible overlap between FWHM’s of neighboured detectors - the fill factor is here defined as that fraction of the sum of the detector cell areas in which a defined MLC misalignment is detectable when the induced percentage signal changes exceed a detection threshold d. Ideally the generalized fill factor may reach 100 %. With user code EGS-chamber and a 2 MeV photon slit beam 0.25 mm wide, both types of the fill factor were calculated for an array with total cell area 100 cm 2 for chamber widths 1–9 mm, using =1mm, d=5%. Results: For single chamber width 5 mm, fill factors were 0.49 (FWHM) and 0.61 (generalized). For chamber width 2 mm the FWHM fill factor was 0.13 whereas the generalized fill factor was 0.32. For chamber widths above 7 mm, the FWHM fill factor exceeds unity, and the general fill factor is exactly 1.00. Conclusions: An updated fill factor definition is introduced which, as a generalization of the FWHM-based definition, more closely estimates the performance of small array chambers and gives a realistic value in the case of overlapping sensitive areas of neighboured chambers. References: 1 A. Gago-Arias, L. Brualla-Gonzalez, D.M. Gonzalez-Castano, F. Gomez, M.S. Garcia, V.L. Vega, J.M. Sueiro, J. Pardo-Montero, “Evaluation of chamber response function influence on IMRT verification using 2D commercial detector arrays,” Phys. Med. Biol. 57, 2005–2020 (2012)

  9. Investigating the cost-effectiveness of videotelephone based support for newly diagnosed paediatric oncology patients and their families: design of a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Theodoros Deborah

    2007-03-01

    Full Text Available Abstract Background Providing ongoing family centred support is an integral part of childhood cancer care. For families living in regional and remote areas, opportunities to receive specialist support are limited by the availability of health care professionals and accessibility, which is often reduced due to distance, time, cost and transport. The primary aim of this work is to investigate the cost-effectiveness of videotelephony to support regional and remote families returning home for the first time with a child newly diagnosed with cancer Methods/design We will recruit 162 paediatric oncology patients and their families to a single centre randomised controlled trial. Patients from regional and remote areas, classified by Accessibility/Remoteness Index of Australia (ARIA+ greater than 0.2, will be randomised to a videotelephone support intervention or a usual support control group. Metropolitan families (ARIA+ ≤ 0.2 will be recruited as an additional usual support control group. Families allocated to the videotelephone support intervention will have access to usual support plus education, communication, counselling and monitoring with specialist multidisciplinary team members via a videotelephone service for a 12-week period following first discharge home. Families in the usual support control group will receive standard care i.e., specialist multidisciplinary team members provide support either face-to-face during inpatient stays, outpatient clinic visits or home visits, or via telephone for families who live far away from the hospital. The primary outcome measure is parental health related quality of life as measured using the Medical Outcome Survey (MOS Short Form SF-12 measured at baseline, 4 weeks, 8 weeks and 12 weeks. The secondary outcome measures are: parental informational and emotional support; parental perceived stress, parent reported patient quality of life and parent reported sibling quality of life, parental satisfaction

  10. European symposium on precision medicine in allergy and airways diseases

    DEFF Research Database (Denmark)

    Muraro, A; Fokkens, W J; Pietikainen, S

    2015-01-01

    David Borrelli and with active participation of the European Respiratory Society (ERS), the European Federations of Allergy and Airways Diseases Patients Associations (EFA), the Global Allergy and Asthma European Network (Ga2len), Allergic Rhinitis and Its Impact on Asthma (ARIA) and the Respiratory....... This report summarizes the key messages delivered during the symposium by the speakers, including the EU Commissioner for Health and Food Safety Vitenys Andriukaitis. The Commissioner underscored the need for optimal patient care in Europe, supporting joint action plans for disease prevention, patient...... the epidemic of Allergy and Asthma in Europe. The socio-economic impact of allergies and chronic airways diseases cannot be underestimated, as they represent the most frequently diagnosed chronic non-communicable diseases in the EU. Despite the fact that 30% of the total European population is nowadays...

  11. Hiel sobre hojaldre.

    Directory of Open Access Journals (Sweden)

    Rúben López.

    1999-11-01

    Full Text Available Fredo Arias de la Canal, poeta, psicoanalista y crítico literario, director del Frente de Afirmación Hispanista y director de la revista de poesía NORTE, plantea un "Psicoanálisis de los arquetipos" de corte Junguiano. En un ensayo titulado "La castración asociada a los símbolos de la sangre y de la herida", afirma que el poeta no necesita ser muy culto siempre y cuando sus metáforas estén pletóricas de arquetipos. Su método se mete con la subjetividad del poeta, más que con su obra, procediendo al contrario del psicoanálisis: aplica el psicoanálisis a la literatura y no la literatura al psicoanálisis.

  12. Japanese guidelines for allergic rhinitis 2017

    Directory of Open Access Journals (Sweden)

    Kimihiro Okubo

    2017-04-01

    To incorporate evidence based medicine (EBM introduced from abroad, the most recent collection of evidence/literature was supplemented to the Practical Guideline for the Management of Allergic Rhinitis in Japan 2016. The revised guideline includes assessment of diagnosis/treatment and prescriptions for children and pregnant women, for broad clinical applications. An evidence-based step-by-step strategy for treatment is also described. In addition, the QOL concept and cost benefit analyses are also addressed. Along with Allergic Rhinitis and its Impact of Asthma (ARIA, this guideline is widely used for various clinical purposes, such as measures for patients with sinusitis, childhood allergic rhinitis, oral allergy syndrome, and anaphylaxis and for pregnant women. A Q&A section regarding allergic rhinitis in Japan was added to the end of this guideline.

  13. Comparison of Nonlinear Model Results Using Modified Recorded and Synthetic Ground Motions

    International Nuclear Information System (INIS)

    Spears, Robert E.; Wilkins, J. Kevin

    2011-01-01

    A study has been performed that compares results of nonlinear model runs using two sets of earthquake ground motion time histories that have been modified to fit the same design response spectra. The time histories include applicable modified recorded earthquake ground motion time histories and synthetic ground motion time histories. The modified recorded earthquake ground motion time histories are modified from time history records that are selected based on consistent magnitude and distance. The synthetic ground motion time histories are generated using appropriate Fourier amplitude spectrums, Arias intensity, and drift correction. All of the time history modification is performed using the same algorithm to fit the design response spectra. The study provides data to demonstrate that properly managed synthetic ground motion time histories are reasonable for use in nonlinear seismic analysis.

  14. Compilation of the opinions expressed by the CCTN in 1997; Raccolta dei pareri espressi dalla CCTN nel 1997

    Energy Technology Data Exchange (ETDEWEB)

    Camoni, I [Istituto Superiore di Sanita` , Rome (Italy). Lab. di Tossicologia Applicata; Mucci, N [ISPESL, Monteporzio Catone, Rome (Italy). Dipt. di Medicina del Lavoro

    1999-12-31

    The advice expressed by the Italian National Advisory Toxicological Committee (CCTN) in 1997 are presented. Among the most important advice, the following may be mentioned: (1) air quality criteria for CO and NO{sub 2}; (2) risk evaluation associated to the presence of mixtures of pesticide residues in food; (3) re-evaluations of the toxic properties of DDT; (4) evaluations of the carcinogenic evidences of several active substances of antiblastic drugs. [Italiano] Vengono presentati i pareri espressi dalla Commissione Consultiva Tossicologica Nazionale (CCTN) nel 1997. Tra i piu` importanti possono essere menzionati i pareri riguardanti: 1) criteri di qualita` dell`aria per il CO e l`NO{sub 2}; 2) rischio tossicologico da residui di miscele di pesticidi presenti negli alimenti; 3) rivalutazione delle proprieta` tossiche del DDT; 4) valutazione dell`evidenza di cancerogenita` di alcuni principi attivi di chemioterapici antiblastici.

  15. The positionality of Localhoods

    DEFF Research Database (Denmark)

    Gyimóthy, Szilvia

    2018-01-01

    The objective of this paper is to develop an explanatory framework to understand the dynamic relationships between tourism mobilities, urban gentrification and the collaborative (peer) economy. The rapid growth of peer accommodation rental in European cities is reshaping the spatial patterns...... of urban tourism, resulting in a wider dispersion of visitors and the emergence of new nodes (Dredge et al. 2016). Although the highest densities of peer accommodation rental are located in the city centres and around major attractions (Arias Sans & Quaglieri Domínguez, 2016; Gutiérrez et al. 2017......), there is also some indication of Airbnb’s “beaten track” extending to residential areas. New tourism nodes are clustered around “localhoods” and reframe tourism consumption around mundane activities, leading to the commodification of everyday life (Richards, 2017). While there is considerable discussion...

  16. Effects of Mie tip-vane on pressure distribution of rotor blade and power augmentation of horizontal axis wind turbine; Yokutan shoyoku Mie ben ni yoru suiheijiku fusha yokumenjo no atsuryoku bunpu no kaizen to seino kojo tono kankei

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, Y.; Maeda, T.; Kamada, Y. [Mie Univ., Mie (Japan); Seto, H. [Mitsubishi Motors Corp., Tokyo (Japan)

    2000-04-01

    By recent developments of exclusive rotor blade, the efficiency of wind turbine is improved substantially. By measuring pressure on rotor blades of horizontal axis wind turbines rotating in wind tunnels, this report clarified relation between improvement of pressure distribution on main rotor blades by Mie vane and upgrade of wind turbine performance. The results under mentioned have been got by measuring pressure distribution on rotor blades, visualization by tuft, and measuring resistance of Mie vane. (1) The difference of pressure between suction surface and pressure surface on the end of rotor blade increase, and output power of wind turbine improves. (2) Vortex of blade end is inhibited by Mie vane. (3) The reason of reduction on wind turbine performance with Mie vane in aria of high rotating speed ratio is the increase of Mie vane flow resistance.(NEDO)

  17. Compilation of the opinions expressed by the CCTN in 1997; Raccolta dei pareri espressi dalla CCTN nel 1997

    Energy Technology Data Exchange (ETDEWEB)

    Camoni, I. [Istituto Superiore di Sanita`, Rome (Italy). Lab. di Tossicologia Applicata; Mucci, N. [ISPESL, Monteporzio Catone, Rome (Italy). Dipt. di Medicina del Lavoro

    1998-12-31

    The advice expressed by the Italian National Advisory Toxicological Committee (CCTN) in 1997 are presented. Among the most important advice, the following may be mentioned: (1) air quality criteria for CO and NO{sub 2}; (2) risk evaluation associated to the presence of mixtures of pesticide residues in food; (3) re-evaluations of the toxic properties of DDT; (4) evaluations of the carcinogenic evidences of several active substances of antiblastic drugs. [Italiano] Vengono presentati i pareri espressi dalla Commissione Consultiva Tossicologica Nazionale (CCTN) nel 1997. Tra i piu` importanti possono essere menzionati i pareri riguardanti: 1) criteri di qualita` dell`aria per il CO e l`NO{sub 2}; 2) rischio tossicologico da residui di miscele di pesticidi presenti negli alimenti; 3) rivalutazione delle proprieta` tossiche del DDT; 4) valutazione dell`evidenza di cancerogenita` di alcuni principi attivi di chemioterapici antiblastici.

  18. Statistical analysis of earthquake ground motion parameters

    International Nuclear Information System (INIS)

    1979-12-01

    Several earthquake ground response parameters that define the strength, duration, and frequency content of the motions are investigated using regression analyses techniques; these techniques incorporate statistical significance testing to establish the terms in the regression equations. The parameters investigated are the peak acceleration, velocity, and displacement; Arias intensity; spectrum intensity; bracketed duration; Trifunac-Brady duration; and response spectral amplitudes. The study provides insight into how these parameters are affected by magnitude, epicentral distance, local site conditions, direction of motion (i.e., whether horizontal or vertical), and earthquake event type. The results are presented in a form so as to facilitate their use in the development of seismic input criteria for nuclear plants and other major structures. They are also compared with results from prior investigations that have been used in the past in the criteria development for such facilities

  19. Building a Math-Positive Culture: How to Support Great Math Teaching in Your School (ASCD Arias)

    Science.gov (United States)

    Seeley, Cathy L.

    2016-01-01

    Cathy L. Seeley, former president of the National Council of Teachers of Mathematics, turns the spotlight on administrative leaders who are seeking to improve their math programs, offering an overview of what an effective program looks like and examples of actions to take to achieve that goal. "Building a Math-Positive Culture" addresses…

  20. TALL HERB SPRUCE FORESTS AS CLIMAX COMMUNITIES ON LOWLAND SWAMPS OF BRYANSK POLESIE

    Directory of Open Access Journals (Sweden)

    O. I. Evstigneev

    2017-09-01

    Full Text Available Nettle grey alder forests are a dominant forest type on lowland swamps in the Bryansk Polesie. They are formed as a result of repeated cuttings in the place of tall herb spruce forests. Tall herb spruce forests are very rare communities in the vegetation cover in this area due to clear cutting, melioration and peat extraction. An assessment of the succession status of tall herb spruce forests and nettle grey alder forests was carried out in this paper. The criteria of climax state and succession state of communities, developed for Eastern European forests, were used. These criteria are based on the degree of intensity of the following signs in the community: 1 the completeness of species composition of tree synusia; 2 the ontogenetic structure of tree species cenopopulation; 3 the gap-mosaic stand structure; 4 the diversity of microsites in soil cover; 5 the completeness of species composition and ecological-coenotic diversity of vascular species. We showed that tall herb spruce forest, as opposed to black alder forest, is close to communities of the climax type. This is evidenced by the following features of cenosis: firstly, all tree species in the area that covers the Bryansk Polesie and that are able to grow on lowland swamps are represented in the spruce forest (Alnus glutinosa, Betula pubescens, Fraxinus excelsior, Padus avium, Picea abies, Salix pentandra, Sorbus aucuparia, Ulmus glabra. Secondly, a steady turnover of generations is carried out in the cenopopulations of main edificators (Picea abies and Alnus glutinosa. This is evidenced by the complete and left-sided structure of their ontogenetic spectrum. Thirdly, a system of asynchronously developing gaps (parcels, which are formed on the site of old tree falls, is formed in the community. This ensures the continuous renewal of spruce and alder populations and creates conditions for the regeneration of other tree species. Fourthly, the structure of biogenic microsites has been formed

  1. Estudos sobre a resistência ao jejum e aspectos nutricionais de Cavernicola lenti Barrett & Arias, 1985 (Hemiptera, Reduviidae, Triatominae Studies on the resistance to fasting and nutritional aspects of Cavernicola lenti Barret & Arias, 1985 (Hemiptera, Reduviida, Triatominae

    Directory of Open Access Journals (Sweden)

    Jane Margaret Costa

    1989-01-01

    Full Text Available In order to widen the present knowledge on the biology of this species, a study on the resistance to starvation was carried out among all nymphal stages and the adult stage (male and female. All evolutive stages were weighed on precision scale in three different nutritional situations: fed, non-fed and death registered after starvation. This procedure has allowed us to calculate the amount of blood taken in each stage and during the whole cycle, the average loss of weight during starvation and its relations with the initial weight. The insects were fed on mice and after eclosion or ecdisis they were isolated for observation of the starving period. Throuhout the whole experiment they were kept in a B. O. D./DOB incubator (28ºC and 90%R.U.. The resistance to starvation of the insects has grown from the first stage on (average of 15.5 days to the fifth stage (average of 75.64 days; on the adult stage, the resistance period was equal to the third stage with an average of 41.76 for the males and 44.82 for the females. The amount of ingested blood was greater at the fifth stage worth 34.14 mg, corresponding to 2,04 times its initial weight. The average weight loss during the starvation was greater at the adult stage (23.95 mg, corresponding to 61.52% of the total weight.

  2. O Espírito Santo contra o feitiço e os espíritos revoltados: "civilização" e "tradição" em Moçambique

    Directory of Open Access Journals (Sweden)

    Peter Fry

    2000-10-01

    Full Text Available Durante uma cerimônia conduzida por uma congregação zionista em Moçambique, para restaurar a fertilidade de um casal mediante o apaziguamento de um espírito enraivecido, foi-me dito que os brancos eram imunes a este tipo de problema pois estavam livres dos espíritos revoltados e da feitiçaria, sendo portanto mais capazes de cooperar entre si. Tal criticismo da "cultura africana" é disseminado entre muitas igrejas protestantes, em particular os Zionistas e Pentecostais, enquanto a Igreja Católica, através de sua noção de enculturação, tenta manter-se próxima à "tradição africana". O artigo examina os significados ligados à "tradição africana" e suas antinomias, "modernidade" e "civilização, em uma tentativa de demonstrar a ampla distribuição do desejo de controlar os males da feitiçaria e da bruxaria, assim como a inveja e ambição que as movem. O artigo se encerra com uma reflexão sobre a maneira como a análise antropológica falhou em considerar o sofrimento que tais crenças refletem e engendram.During a ceremony conducted by a Zionist congregation in Mozambique to restore the fertility of a barren couple by appeasing an angry spirit, I was told that whites were immune from these kinds of problems since they were free of angry spirits and witchcraft and more able to co-operate among themselves. Such criticism of "African culture" is widespread among many Protestant churches, in particular the Zionists and Pentecostals in general. Meanwhile, the Catholic Church, through its notion of enculturation, attempts to become closer to "African Tradition". The article examines the meanings attached to "African Tradition" and its antinomies, "Modernity" and "Civilization", in an attempt to demonstrate the widespread existence of a strong desire to control the evils of witchcraft, sorcery, and the jealousy and ambition that move them. The article ends with a brief reflection on the way in which much classical anthropological

  3. Funcionamiento familiar en familias víctimas de abuso sexual intrafamiliar-incesto

    Directory of Open Access Journals (Sweden)

    Ibeth Villanueva Sarmiento

    2011-01-01

    Full Text Available Abstract This article of research describes family functioning in victims of domestic sexual abuse (incest in the city of Barranquilla and the following dimension were taken in account: a Familiar adaptation to face up conflict situations, b Level of participation and emotional growth in each one of the members and c Affective relationships and commitments between family members. That is a descriptive study and Familiar APGAR test, which measures the rank of family functionality, proposed by Gabriel Smilkstein (1978, modify for Colombia by Liliana Arias (2006 was used. The sample was ten (10 members of families, victims of domestic sexual abuse (incest that received the clinical intervention en the “Centro de Atención Integral e Investigación para Víctimas de Abuso Sexual” (CAIVAS in the Barranquilla city. The results shows that 20% of the total population presents a severe family dysfunction, a 0% a moderate family dysfunction, a 20% a slight dysfunction and finally a 60% presented a normal familiar functionality. Resumen El presente artículo de investigación describe el funcionamiento familiar en víctimas de abuso sexual intrafamiliar (incesto en la ciudad de Barranquilla, teniendo en cuenta las siguientes dimensiones: a adaptación familiar para afrontar situaciones de conflicto, b nivel de participación y crecimiento emocional de sus miembros y c relaciones afectivas y compromisos existentes entre los miembros de familias. Se realizó un estudio descriptivo mediante la aplicación del test de APGAR Familiar propuesto por Smilkstein (1989, modificado para Colombia por Arias (2006, el cual mide el grado de funcionalidad familiar. Se aplicó a una muestra de diez (10 miembros de familias víctimas de abuso sexual intrafamiliar (incesto que recibían intervención clínica en el Centro de Atención Integral e Investigación para Víctimas de Abuso Sexual (CAIVAS de la ciudad de Barranquilla. Los resultados obtenidos permiten afirmar

  4. 180 meteorological stations data analysis to find out a meteodiffusivity index of sites; Analisi dei dati relativi a 180 stazioni meteorologiche al fine di individuare un indice per la caratterizzazione meteodiffusiva dei siti

    Energy Technology Data Exchange (ETDEWEB)

    Cagnetti, P.; Grandoni, G.; Mammarella, M.C.; Pellegrini, A.; Racalbuto, S.; Boccadoro, M.; Fedele, P. [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente

    1999-07-01

    The present work has been done during the preparatory events of the National Conference on Energy and Environment (CNEA), studying the diffusive properties of the lower layers of the atmosphere, in order to find out a set of air quality indicators for urban areas. The data of 180 meteorological stations of the Italian Air Force Meteorological Service cover the whole Italian territory and are easily available; for this reason, this study, is based on those data. By analysing the available data, the variability range of the considered parameters was investigated and then an attempt was done to combine those parameters in order to describe, with a general index related to each site, the higher or lower attitude to diffuse pollutants released in the atmosphere. After that, the sites have been classified by their capacity of dispersion in atmosphere, making use of the meteo-diffusivity index described above, and pointing out the importance of meteorology in the study of the air quality of urban sites. [Italian] Questo lavoro e' stato svolto durante gli eventi preparatori della Conferenza Nazionale Energia Ambiente (CNEA), con lo scopo di individuare un set di indicatori della qualita' dell'aria in aree urbane, sulla base di studi e ricerche sui parametri meteodiffusivi dei bassi strati dell'atmosfera. Sono stati presi in considerazione, perche' subito fruibili e a diffusione nazionale, i dati provenienti dalle 180 stazioni meteorologiche dell'Areonautica Militare. Dopo un'analisi di tali dati al fine di individuare l'intervallo di variabilita' dei parametri meteorologici presi in considerazione, e' stata proposta una combinazione di tali parametri in grado di descrivere, sotto forma di un indice generale ed in relazione a tutti i siti considerati, la maggiore o minore tendenza alla diffusione degli inquinanti immessi in atmosfera. Sulla base di tale definizione di un indice di meteodiffusivita', sono stati

  5. Large-Scale Sentinel-1 Processing for Solid Earth Science and Urgent Response using Cloud Computing and Machine Learning

    Science.gov (United States)

    Hua, H.; Owen, S. E.; Yun, S. H.; Agram, P. S.; Manipon, G.; Starch, M.; Sacco, G. F.; Bue, B. D.; Dang, L. B.; Linick, J. P.; Malarout, N.; Rosen, P. A.; Fielding, E. J.; Lundgren, P.; Moore, A. W.; Liu, Z.; Farr, T.; Webb, F.; Simons, M.; Gurrola, E. M.

    2017-12-01

    With the increased availability of open SAR data (e.g. Sentinel-1 A/B), new challenges are being faced with processing and analyzing the voluminous SAR datasets to make geodetic measurements. Upcoming SAR missions such as NISAR are expected to generate close to 100TB per day. The Advanced Rapid Imaging and Analysis (ARIA) project can now generate geocoded unwrapped phase and coherence products from Sentinel-1 TOPS mode data in an automated fashion, using the ISCE software. This capability is currently being exercised on various study sites across the United States and around the globe, including Hawaii, Central California, Iceland and South America. The automated and large-scale SAR data processing and analysis capabilities use cloud computing techniques to speed the computations and provide scalable processing power and storage. Aspects such as how to processing these voluminous SLCs and interferograms at global scales, keeping up with the large daily SAR data volumes, and how to handle the voluminous data rates are being explored. Scene-partitioning approaches in the processing pipeline help in handling global-scale processing up to unwrapped interferograms with stitching done at a late stage. We have built an advanced science data system with rapid search functions to enable access to the derived data products. Rapid image processing of Sentinel-1 data to interferograms and time series is already being applied to natural hazards including earthquakes, floods, volcanic eruptions, and land subsidence due to fluid withdrawal. We will present the status of the ARIA science data system for generating science-ready data products and challenges that arise from being able to process SAR datasets to derived time series data products at large scales. For example, how do we perform large-scale data quality screening on interferograms? What approaches can be used to minimize compute, storage, and data movement costs for time series analysis in the cloud? We will also

  6. Comentario en el aula del poema «Al ruido del Duero» de Claudio Rodríguez

    Directory of Open Access Journals (Sweden)

    María Antonia MEZQUITA FERNÁNDEZ

    2009-11-01

    Full Text Available RESUMEN: En el siguiente artículo se tratará de reflejar la experiencia en un aula de Educación Primaria para acercar a los niños la figura de Claudio Rodríguez y centrarnos en un comentario de su poema «Al ruido del Duero». El colegio elegido es el «Arias Gonzalo», de Zamora. Los niños participaron activamente a la hora de aportar ideas y de comentar el texto. Claudio Rodríguez se sentía fascinado y profesaba un gran amor a su tierra, a sus costumbres y al río Duero. Consideraba que los valores más relevantes del ser humano eran la sencillez, la solidaridad y la fraternidad y deseaba unirse y fundirse, primero, con el entorno natural y, después, con los hombres. En mi opinión, la respuesta de los alumnos fue positiva, ya que captaron la esencia de los versos y demostraron, con su colaboración, que los elementos usados para motivarles habían servido. Lo dejaron patente en las cartas, dibujos y poemas que realizaron posteriormente.ABSTRACT: The following article will try to show a commentary on the poem «Al ruido del Duero» by Claudio Rodríguez, from Zamora. The school which was chosen is called «Arias Gonzalo»; it is in Zamora too. The pupils took part actively and their ideas contributed to comment the text. Claudio Rodríguez was fascinated and professed huge love for the place where he was born, the customs of his province and The Duero River. He believed that the most important human values were simplicity, solidarity and brotherhood. First of all, he wished to be bound to nature. As far as mankind is concerned, he always desired to be joined together. In my opinion, the pupils answered positively and they understood the essence of the verses. They all proved that the elements for motivating them were useful. Then, they showed it clearly by drawing pictures, writing letters and poems.

  7. Socio-economic predictors of performance in the Undergraduate Medicine and Health Sciences Admission Test (UMAT).

    Science.gov (United States)

    Puddey, Ian B; Mercer, Annette

    2013-11-29

    Entry from secondary school to Australian and New Zealand undergraduate medical schools has since the late 1990's increasingly relied on the Undergraduate Medicine and Health Sciences Admission Test (UMAT) as one of the selection factors. The UMAT consists of 3 sections - logical reasoning and problem solving (UMAT-1), understanding people (UMAT-2) and non-verbal reasoning (UMAT-3). One of the goals of using this test has been to enhance equity in the selection of students with the anticipation of an increase in the socioeconomic diversity in student cohorts. However there has been limited assessment as to whether UMAT performance itself might be influenced by socioeconomic background. Between 2000 and 2012, 158,909 UMAT assessments were completed. From these, 118,085 cases have been identified where an Australian candidate was sitting for the first time during that period. Predictors of the total UMAT score, UMAT-1, UMAT-2 and UMAT-3 scores were entered into regression models and included gender, age, school type, language used at home, deciles for the Index of Relative Socioeconomic Advantage and Disadvantage score, the Accessibility/Remoteness Index of Australia (ARIA), self-identification as being of Aboriginal or Torres Strait Islander origin (ATSI) and current Australian state or territory of abode. A lower UMAT score was predicted by living in an area of relatively higher social disadvantage and lower social advantage. Other socioeconomic indicators were consistent with this observation with lower scores in those who self-identified as being of ATSI origin and higher scores evident in those from fee-paying independent school backgrounds compared to government schools. Lower scores were seen with increasing age, female gender and speaking any language other than English at home. Divergent effects of rurality were observed, with increased scores for UMAT-1 and UMAT-2, but decreasing UMAT-3 scores with increasing ARIA score. Significant state-based differences

  8. Actitud de universitarios hacia las personas con discapacidad

    Directory of Open Access Journals (Sweden)

    Alexis Araya-Cortés

    2014-08-01

    Full Text Available El objetivo de este estudio fue describir y comparar la actitud hacia las personas con discapacidad de estudiantes de pedagogía, con estudiantes de otras profesiones y en distintos niveles de formación. Se utilizó un diseño descriptivo y correlacional en el que participaron 260 estudiantes de ambos sexos de una universidad privada de la cuidad de La Serena, Chile. Como instrumento se aplicó la Escala de Actitudes hacia las Personas con Discapacidad de Verdugo, Jenaro y Arias. Los resultados mostraron que la totalidad del alumnado presenta actitudes positivas. En relación con el tipo de carrera y nivel de estudio no se encontraron diferencias estadísticamente significativas. Se puede inferir que los estudiantes presentan una predisposición favorable a comportarse de manera efectiva frente a personas con discapacidad, valorando positivamente sus capacidades y reconociendo sus derechos fundamentales.

  9. Il portale del Servizio Geologico d’Italia

    Directory of Open Access Journals (Sweden)

    Loredana Battaglini

    2006-12-01

    politiche di businness agreement tra le varie major. L'utilizzo dei dispositivi GPS è davvero ancora arenato alla semplice ricerca di un percorso o di un indirizzo da raggiungere? L'uso di tali apparecchiature può inserirsi all'interno di target quali l'intrattenimento e le attività ricreative? Negli ultimi anni stiamo riscoprendo la bellezza della natura e il piacere di dedicarci ad una serie di attività sportive outdoor che ci conciliano con essa, unendo ai benefici della mente quelli del corpo derivanti da una corretta sollecitazione della propria frequenza cardiaca. Questa mia relazione vuole essere un diario di viaggio nelle quotidiane attività all'aria aperta di un atleta non professionista, praticate durante le quattro stagioni sfruttando le tecnologie legate alla triangolazione satellitare.

  10. AN OVERVIEW AT MACROECONOMIC LEVEL THROUGH ACCOUNTING FIGURES PROVIDED BY THE ECB ASSESSMENT ON EUROZONE BANKING SYSTEM

    Directory of Open Access Journals (Sweden)

    Olivera Ecaterina OROS

    2014-05-01

    Full Text Available Along with the main macroeconomic indicators, the credit risk indicators became an important leverage in monitoring and evaluating the standard of living at a national level and the country’s economic evolution. These two types of indicators show a strong interconnection, and the correct assessment of the credit risk indicators becomes a must. As a consequence, the central banks and the main regulators in the Europe aria provided for a strict monitoring of such indicators and further on, for constant update of the banking supervisory regulations. In October 2013, the European Central bank (ECB issued the Note of Comprehensive Assessment that will be carried out during 2014, on the Euro-zone1 banking system. The outcome of the assessment will impact not only the accounting figures of the banking system, but also might change the macroeconomic overview of Euro-zone and the IASB's Conceptual Framework for Financial Reporting.

  11. Studio di prototipo di calorimetro per neutroni per l'esperimento ALICE

    CERN Document Server

    Arnaldi, R; Cicalò, C; Cortese, P; De Falco, A; Dellacasa, G; De Marco, N; Gallio, M; Macciotta, P; Masoni, A; Musso, A; Oppedisano, C; Piccotti, A; Puddu, G; Scomparin, E; Siddi, S; Serci, E; Soave, C; Usai, G L; Vercellin, Ermanno

    1999-01-01

    ALICE e uno dei quattro esperimenti previsti ad LHC, al CERN, il cui scopo e lo studio delle osservabili che danno informazioni rilevanti sulla formazione del quark gluon plasma, che potrebbe essere prodotto in collisioni centrali Pb-Pb, di energia nel centro di massa di 5.5 A TeV.Il parametro di impatto di tali collisioni verra determinato grazie ad un insieme di calorimetri per protoni e neutroni che misureranno l'energia portata in avanti dai nucleoni non interagenti(spettatori).E' stato costruito un prototipo di calometro per neutroni, formato da piani di fibre di quarzo, posti a 45 gradi rispetto all'asse del fascio e inframmezzati da piani di materiale passivo denso(tungsteno). La luce Cerenkov prodotta nelle fibre dallo sciame sviluppato nel materiale passivo,viene raccolta da guide ottiche in aria.Verranno presentati i rilustati di un test previsto al CERN SPS per il luglio 1999.

  12. Conventional Leasing vs Islamic Leasing

    Directory of Open Access Journals (Sweden)

    Violeta ISAI

    2014-12-01

    Full Text Available Leasing developed in time, from the simple form of renting to the modern modality of financial from nowadays, as an alternative for loan. It is present in the entire world, being used both by the financial specialized companies and banks, and the clients are companies and population. The object of leasing contract can be assets and also services, which are rented by the financier (lessor, on definite period, to the client (lessee, in exchange for a leasing rate (rent. The registering in accounting and the fiscal implications in the companies financial administration are different, according to the leasing form which they are using. The capitalist system has in view to obtain profit from renting, but the Islamic System, based on Șaria, forbids renting “haram” assets and services, obtaining interest from renting and using the leasing contract for the transfer of the property.

  13. LA LUDOPATÍA Y LOS DOCENTES EN LA UNIVERSIDAD DE SAN BUENAVENTURA, SECCIONAL DE MEDELLÍN, COLOMBIA – 2010

    Directory of Open Access Journals (Sweden)

    Jorge Arturo Pérez Pérez

    2010-06-01

    Full Text Available This current study consists of a description of theuse of games of chance and videogames by thestudents, instructors and employees at SaintBonaventure University, Medellin branch andtheir relations with the medical andpsychological dimensions in which the followingvariables were involved: difficulties forconcentration, frame of mind, physicaldiscomfort, the preference of games to sports, aswell as the relaxed atmosphere produced by thegame; in this second stage, the results given dealwith university instructors. Federico Burgos Acevedo, Head of Roger Bacon Research Center, is responsible for the Epi-Info tethodological assistantship. This study is endorsed by the Interdisciplinary Group of Psychosocial Studies in Addictions –GIEPSA – which is coordinated by Víctor Hugo Cano B, and Jorge Arturo Pérez P., being the main researcher, who belongs to the Research and Attention Center to the Drug Addict – CIAF –, which is directed by Francisco Javier Arias Zapata.

  14. Starting School Right: How Do I Plan for a Successful First Week in My Classroom? (ASCD Arias)

    Science.gov (United States)

    Kriegel, Otis

    2016-01-01

    Packed with ideas for both new and veteran teachers of K-8 students, this book touches on a variety of topics that are especially relevant to the first week of school. The author provides critical information that includes arranging and navigating the classroom, setting basic expectations, communicating routines, and understanding your students'…

  15. Songs as a Medium for Embedded Reproductive Messages

    Directory of Open Access Journals (Sweden)

    Dawn R. Hobbs

    2011-07-01

    Full Text Available Research shows that sensational news stories as well as popular romance novels often feature themes related to important topics in evolutionary psychology. In the first of four studies described in this paper we examined the song lyrics from three Billboard charts: Country, Pop, and R&B. A content analysis of the lyrics revealed 18 reproductive themes that read like an outline for a course in evolutionary psychology. Approximately 92% of the 174 songs that made it into the Top Ten in 2009 contained one or more reproductive messages, with an average of 10.49 reproductive phrases per song. Although differences in the frequency of different themes between charts were found, further analyses showed that the most popular/bestselling songs contained significantly more reproductive messages. An analysis of the lyrics of opera arias and art songs also revealed evidence for many of the same embedded reproductive messages extending back more than 400 years.

  16. MORPHOLOGICAL CHARACTERISTICS FOR CLASSIFICATION OF GENUS MACROPODUS LACÉPÈDE, 1801 IN GIANH RIVER IN THE NORTH CENTRAL PART OF VIETNAM

    Directory of Open Access Journals (Sweden)

    Ho Anh TUAN

    2015-12-01

    Full Text Available Analysis and identification of 57 specimens of genus Macropodus Lacépède collected from Gianh River in Quang Binh province in north center region Vietnam. We have classified three species: Macropodus erythropterus (Frey. & Her., 2002, Macropodus opercularis (Linneaeus, 1758, Macropodus spechti (Schreitmüller, 1936 was first discovered in the study area and north center region Vietnam.CARACTERISTICA MORFOLOGICĂ PENTRU CLASIFICAREA GENULUI MACROPODUS LACÉPÈDE, 1801 DIN BAZINUL RÂULUI GIANH, REGIUNEA CENTRALĂ DE NORD A VIETNAMULUIAu fost analizate şi identificate 57 de exemplare ale genului Macropodus Lacépède colectate din bazinul râului Gianh, provincia Quang Binh, regiunea centrală de nord a Vietnamului. Noi am clasificat 3 specii: Macropodus erythropterus (Frey. & Her., 2002, Macropodus opercularis (Linneaeus, 1758 şi Macropodus spechti (Schreitmüller, 1936, descoperite în aria de studiu şi în regiunea centrală de nord a Vietnamului.

  17. Giuditta versus Oloferne. Un percorso didattico sull’oratorio musicale

    Directory of Open Access Journals (Sweden)

    Maria Rosa De Luca

    2012-11-01

    Full Text Available This paper focuses on La Giuditta, an oratorio in vernacular composed by Alessandro Scarlatti on a libretto by Antonio Ottoboni. Based on a Bible’s deuterocanonical book, the story of the successful deeds of Judith, a beautiful Hebrew who decides to face the terrible Holofernes in order to save Israel, inspired poetic and music-dramatic features of lots of oratorios. Due to her high exemplary virtues, she is frequently represented in figurative arts, as well as in literature, where biblical memory meets poetic invention. So far, this subject gives the opportunity to structure a didactic project, relying music, considered as a point of departure, with historical, artistic and literary disciplines. Two sessions of didactics of listening based respectively on the duet Judith-Nurse, “Deh, rifletti al gran cimento”, and Holofernes’ aria “Togliti da quest’occhi”, in order to introduce the three main characters of Scarlatti’s oratorio and to illustrate two important moments of the plot.

  18. Complex of fiber and effects of mix spinning; Sen'i no fukugoka to konbo no koka

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, N. [Asahi Chemical Industry Corp., Tokyo (Japan)

    2000-03-01

    In recently, comfortable life can be spent by performing complex of fibers. As complex of single fibers being materials of yarn, conjugate fiber is listed. Conjugate fiber is a fiber spun over 2 kind of polymer having different characteristics from one nozzle. There are sheath core type fibers as complex functional fibers. Static electricity prevention fibers can be prepared by putting conductive materials, for example, carbon black into core parts. After putting components being able to dissolve by specific solvents into core, hollow fibers can be prepared by dissolving core parts in near process to products. By reason of clothing contacting to skin directly in board aria and long time, fashionable characters of design and so on or comfortability of wearing are needed in many cases. In this reason, many kinds of fibers for clothing prepared complex yarn by being complex and by making the best use of good characteristics of each fibers, and developed a way to new function or new use. (NEDO)

  19. Influence of Cryogenic Treatments on the Wear Behavior of AISI 420 Martensitic Stainless Steel

    Science.gov (United States)

    Prieto, G.; Tuckart, W. R.

    2017-11-01

    The objective of the present work is to characterize the wear behavior of a cryogenically treated low-carbon AISI 420 martensitic stainless steel, by means of ball-on-disk tribological tests. Wear tests were performed under a range of applied normal loads and in two different environments, namely a petrolatum bath and an argon atmosphere. Wear tracks were analyzed by both optical and scanning electron microscopy and Raman spectroscopy to evaluate wear volume, track geometry, surface features and the tribolayers generated after testing. This paper is an extension of the work originally reported in the VIII Iberian Conference of Tribology (Prieto and Tuckart, in: Ballest Jiménez, Rodríguez Espinosa, Serrano Saurín, Pardilla Arias, Olivares Bermúdez (eds) VIII Iberian conference of tribology, Cartagena, 2015). In this study, it has been experimentally demonstrated that cryogenically treated specimens showed a wear resistance improvement ranging from 35 to 90% compared to conventionally treated ones.

  20. Empathy manipulation impacts music-induced emotions: a psychophysiological study on opera.

    Directory of Open Access Journals (Sweden)

    Andrei C Miu

    Full Text Available This study investigated the effects of voluntarily empathizing with a musical performer (i.e., cognitive empathy on music-induced emotions and their underlying physiological activity. N = 56 participants watched video-clips of two operatic compositions performed in concerts, with low or high empathy instructions. Heart rate and heart rate variability, skin conductance level (SCL, and respiration rate (RR were measured during music listening, and music-induced emotions were quantified using the Geneva Emotional Music Scale immediately after music listening. Listening to the aria with sad content in a high empathy condition facilitated the emotion of nostalgia and decreased SCL, in comparison to the low empathy condition. Listening to the song with happy content in a high empathy condition also facilitated the emotion of power and increased RR, in comparison to the low empathy condition. To our knowledge, this study offers the first experimental evidence that cognitive empathy influences emotion psychophysiology during music listening.

  1. The protection of urban areas from surface wastewater pollutions

    Directory of Open Access Journals (Sweden)

    Vialkova Elena

    2017-01-01

    Full Text Available In this paper it considered the problem of collection, treatment and discharge into waters of rain and melted wastewater. To reduce the load on the combined sewer system, there are engineering solutions collect rain and melt water for use in the irrigation of lawns and green spaces. Research carried out at the department “Water supply and sanitation”, (Russia, confirm the high pollution concentrations of meltwater and rainfall in urban arias. Series of measurements of heavy metal in rainwater runoff carried out in Hungary demonstrates clearly the differences in concentrations in the function of distance from the edge of the road. Also differences are introduced between pollution concentrations in runoff water from within and outside urban traffic roads. The quality of snow cover, forming meltwater is observed to be changing in dependence on roadway location. Quality characteristics of surface runoff and its sediments can be effectively improved with super-high frequency radiation (SHF treatment which is presented in this paper.

  2. SISMA (Site of Italian Strong Motion Accelerograms): a Web-Database of Ground Motion Recordings for Engineering Applications

    International Nuclear Information System (INIS)

    Scasserra, Giuseppe; Lanzo, Giuseppe; D'Elia, Beniamino; Stewart, Jonathan P.

    2008-01-01

    The paper describes a new website called SISMA, i.e. Site of Italian Strong Motion Accelerograms, which is an Internet portal intended to provide natural records for use in engineering applications for dynamic analyses of structural and geotechnical systems. SISMA contains 247 three-component corrected motions recorded at 101 stations from 89 earthquakes that occurred in Italy in the period 1972-2002. The database of strong motion accelerograms was developed in the framework of a joint project between Sapienza University of Rome and University of California at Los Angeles (USA) and is described elsewhere. Acceleration histories and pseudo-acceleration response spectra (5% damping) are available for download from the website. Recordings can be located using simple search parameters related to seismic source and the recording station (e.g., magnitude, V s30 , etc) as well as ground motion characteristics (e.g. peak ground acceleration, peak ground velocity, peak ground displacement, Arias intensity, etc.)

  3. Musical metaphors: evidence for a spatial grounding of non-literal sentences describing auditory events.

    Science.gov (United States)

    Wolter, Sibylla; Dudschig, Carolin; de la Vega, Irmgard; Kaup, Barbara

    2015-03-01

    This study investigated whether the spatial terms high and low, when used in sentence contexts implying a non-literal interpretation, trigger similar spatial associations as would have been expected from the literal meaning of the words. In three experiments, participants read sentences describing either a high or a low auditory event (e.g., The soprano sings a high aria vs. The pianist plays a low note). In all Experiments, participants were asked to judge (yes/no) whether the sentences were meaningful by means of up/down (Experiments 1 and 2) or left/right (Experiment 3) key press responses. Contrary to previous studies reporting that metaphorical language understanding differs from literal language understanding with regard to simulation effects, the results show compatibility effects between sentence implied pitch height and response location. The results are in line with grounded models of language comprehension proposing that sensory motor experiences are being elicited when processing literal as well as non-literal sentences. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Estratégias de leitura da tradição literária brasileira na crítica de Machado de Assis

    Directory of Open Access Journals (Sweden)

    Andréa Sirihal Werkema

    Full Text Available Neste artigo, são discutidas as estratégias utilizadas por Machado de Assis, em seu célebre ensaio "Instinto de nacionalidade" (1873, para não apenas inserir a sua própria produção literária no quadro da literatura brasileira de então, mas também para lançar um olhar sobre as futuras possibilidades, a partir daquele momento, de produção de uma literatura não pautada pelo crivo do nacionalismo literário no Brasil. Ou seja, o ensaio de Machado lançaria, para nós, leitores a posteriori, uma luz especial sobre a futura obra ficcional do autor, já que ele proporia um princípio de indeterminação do índice diferenciador dos textos da literatura brasileira, índice até então associado aos traços brasileiristas aí encontrados.

  5. La nueva ruralidad en México

    Directory of Open Access Journals (Sweden)

    Javier Delgado Campos

    1999-04-01

    Full Text Available In many developed countries, urban diffusion shakes traditional rural areas so strong that agrarian activity is no longer one, nor the most important characteristic of "rural life", particularly in the periurban zone of most dynamic cities. This has been conceptualized as "new rurality" or "rurbanization", that may replace old terms based on center-pheriphery model by those of homogeneity and diversity issued from the new global ordering. Mexico seems to go in the same way, if we attend to the emergency of a periurban agriculture based on new productive technics (Lara, 1996; Arias, 1992, the reordering of production and consumption processes in most dynamic regions that isolate the rest of the territory (Delgadillo, 1993, at the same time of a sociospatial reestructuring of the national urban system (Aguilar and Rodriguez, 1996. In brief, it is possible to verify the persistence of rurality and deepening of uneven relationship between privileged centers and a wider rural periphery.

  6. Characterisation of IncA/C2 plasmids carrying an In416-like integron with the blaVIM-19 gene from Klebsiella pneumoniae ST383 of Greek origin.

    Science.gov (United States)

    Papagiannitsis, Costas C; Dolejska, Monika; Izdebski, Radosław; Giakkoupi, Panagiota; Skálová, Anna; Chudějová, Kateřina; Dobiasova, Hana; Vatopoulos, Alkiviadis C; Derde, Lennie P G; Bonten, Marc J M; Gniadkowski, Marek; Hrabák, Jaroslav

    2016-02-01

    The complete nucleotide sequences of three multidrug resistance (MDR) IncA/C-like plasmids from Enterobacteriaceae isolates carrying the VIM-type carbapenemase-encoding integrons In4863 (blaVIM-19-aacA7-dfrA1-ΔaadA1-smr2) or In4873 (blaVIM-1-aacA7-dfrA1-ΔaadA1-smr2) were determined, which are the first In416-like elements identified in Greece. Plasmids pKP-Gr642 and pKP-Gr8143 were from Klebsiella pneumoniae ST383 isolates, whereas plasmid pEcl-Gr4873 was from an Enterobacter cloacae ST88 isolate. Sequencing showed that pKP-Gr642 (162787bp) and pKP-Gr8143 (154395bp) consisted of the type 1 IncA/C2 conserved backbone, the blaCMY-2-like gene-containing region, and the ARI-B (with the sul2 gene) and ARI-A (with a class 1 integron) resistance islands, like the plasmid pUMNK88_161 from the USA. The third plasmid, pEcl-Gr4873 (153958bp), exhibited extensive similarity with the type 2 IncA/C2 plasmid pR55 from France. pEcl-Gr4873 carried only one resistance island of a hybrid transposon structure inserted in a different location to ARI-A in type 1 A/C2 plasmids. In all three plasmids, the In416-like integrons In4863 or In4873 were identified within non-identical class II transposon structures. All three In416-like-carrying regions presented significant similarities with the MDR region of the IncA/C2 plasmid pCC416 from Italy, carrying the prototype In416 integron (blaVIM-4-aacA7-dfrA1-ΔaadA1-smr2). These findings provided the basis for speculations regarding the evolution of IncA/C2 plasmids with In416-like integrons, and confirmed the rapid evolution of some IncA/C2 plasmid lineages. Considering the broad host range of IncA/C2 molecules, it seems that pKP-Gr642, pKP-Gr8143 and pEcl-Gr4873 plasmids might support the diffusion of In416-like integrons among Enterobacteriaceae. Copyright © 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

  7. Making Sense of Math: How to Help Every Student become a Mathematical Thinker and Problem Solver (ASCD Arias)

    Science.gov (United States)

    Seeley, Cathy L.

    2016-01-01

    In "Making Sense of Math," Cathy L. Seeley, former president of the National Council of Teachers of Mathematics, shares her insight into how to turn your students into flexible mathematical thinkers and problem solvers. This practical volume concentrates on the following areas: (1) Making sense of math by fostering habits of mind that…

  8. Reseñas

    Directory of Open Access Journals (Sweden)

    HC Reseñas

    2010-02-01

    Sebastián durante la Restauración (1875-1914. Fundación Caja Guipúzcoa-Kutxa. San Sebastián, 1999. ARIAS GONZÁLEZ, Luis y LUIS MARTÍN, Francisco. La narrativa breve socialista en España. Antología (1890-1936 UGT/Centro de Estudios Históricos. Madrid, 1998. LUIS MARTÍN, Francisco de y ARIAS GONZÁLEZ, Luis. Catálogo de la Biblioteca de la Casa del Pueblo de Madrid (1908-1939 [Estudio histórico]. Comunidad de Madrid-Fundación Largo Caballero. Madrid, 1998. RICHARDS, Michael. Un tiempo de silencio. La Guerra Civil y la cultura de la represión en la España de Franco. Crítica. Barcelona, 1999. MORENO FONSERET, Roque y SEVILLANO CALERO, Francisco (eds. El franquismo. Visiones y balances. Universidad de Alicante. Alicante, 1999. SANZ ALBEROLA, Daniel. La implantación del franquismo en Alicante. El papel del Gobierno Civil (1939-1946. Universidad de Alicante. Alicante, 1999. CUESTA BUSTELLO, Josefina (ed. Retornos (De exilios y migraciones. Fundación Francisco Largo Caballero. Madrid, 1999. LUIS MARTÍN, Francisco de y ARIAS GONZÁLEZ Luis. De O Grove a Cuba (1937-1964. Memorias de Juan Aguiño: pescador y exiliado. Edicions do Castro. A Coruña, 2000. SARTORIUS, Nicolás y ALFAYA, Javier. La memoria insumisa. Sobre la dictadura de Franco. Espasa. Madrid, 1999. UGARTE, Javier (ed. La transición en el País Vasco y España. Historia y memoria. UPV/EHU. Bilbao, 1998.

  9. Application of a time probabilistic approach to seismic landslide hazard estimates in Iran

    Science.gov (United States)

    Rajabi, A. M.; Del Gaudio, V.; Capolongo, D.; Khamehchiyan, M.; Mahdavifar, M. R.

    2009-04-01

    Iran is a country located in a tectonic active belt and is prone to earthquake and related phenomena. In the recent years, several earthquakes caused many fatalities and damages to facilities, e.g. the Manjil (1990), Avaj (2002), Bam (2003) and Firuzabad-e-Kojur (2004) earthquakes. These earthquakes generated many landslides. For instance, catastrophic landslides triggered by the Manjil Earthquake (Ms = 7.7) in 1990 buried the village of Fatalak, killed more than 130 peoples and cut many important road and other lifelines, resulting in major economic disruption. In general, earthquakes in Iran have been concentrated in two major zones with different seismicity characteristics: one is the region of Alborz and Central Iran and the other is the Zagros Orogenic Belt. Understanding where seismically induced landslides are most likely to occur is crucial in reducing property damage and loss of life in future earthquakes. For this purpose a time probabilistic approach for earthquake-induced landslide hazard at regional scale, proposed by Del Gaudio et al. (2003), has been applied to the whole Iranian territory to provide the basis of hazard estimates. This method consists in evaluating the recurrence of seismically induced slope failure conditions inferred from the Newmark's model. First, by adopting Arias Intensity to quantify seismic shaking and using different Arias attenuation relations for Alborz - Central Iran and Zagros regions, well-established methods of seismic hazard assessment, based on the Cornell (1968) method, were employed to obtain the occurrence probabilities for different levels of seismic shaking in a time interval of interest (50 year). Then, following Jibson (1998), empirical formulae specifically developed for Alborz - Central Iran and Zagros, were used to represent, according to the Newmark's model, the relation linking Newmark's displacement Dn to Arias intensity Ia and to slope critical acceleration ac. These formulae were employed to evaluate

  10. On eradication of woody plants with herbicides in fields and pastures

    Directory of Open Access Journals (Sweden)

    Jaakko Mukula

    1950-01-01

    Full Text Available On the initiative of the Department of Plant Husbandry of Agricultural Research Institute, experiments for destroying woody plants on fields and pastures were conducted in 1948—1949 with the following chemicals: Artificial hormones (sodium salt of 2,4-D, morpholine of 2,4-D, triethanolamine of 2,4-D, ethyl ester of 2,4-D, butyl ester of 2,4-D, and sodium salt of 2M-4K, potassium chlorate, and ammonium salt of dinitro-ortochresol. The substances Were applied in aqueous solutions, or as emulsions. Three different methods Were used: spray application to foliage, absorption through a cut branch, and application to soil. The following thicket-forming woody plants, common in Finland, were investigated: grey alder, Alnus incana (L. Willd., willow, Salix sp., birch, Betula sp., mountain ash, Sorbus aucuparia L., and aspen, Populus tremula L. Following conclusions have been drawn from the experiments; It is possible, and, probably with the exception of aspen, even advisable to destroy small sprouts, 0.5—1.5 m. in height, of these woody plants by spraying their foliage with artificial hormones early in summer, especially if mechanical clearing machines cannot be used. Of the experimented substances, esters of 2,4-D proved the most effective in spray applications, but satisfactory results were even secured with other artificial hormones. For different species of woody plants the necessary concentration of the solution varies from 0.1 to 0.4 % of the active substance (p. 6. For dense thickets, 0.5—1.5 m. in height, the amount of solution used Was 1250—2000 l. per ha., applied by means of knapsack type of pressure sprayers. All branches must be sprayed. It is difficult to make the treatment effective enough, if only one application is made. Therefore it is important to conduct a new control spraying after 2—3 weeks. Treatment is most effective, if given in Warm, sunny weather. The best results are secured with spraying towards the end of June or at

  11. La materia dei sogni Sbirciatina su un mondo di cose soffici (lettore compreso)

    CERN Document Server

    Piazza, Roberto

    2010-01-01

    Dall’aria che respiriamo ai cibi di cui ci nutriamo, dai vestiti che indossiamo ai detersivi con cui li laviamo, dai colori con cui dipingiamo agli schermi su cui li guardiamo, la nostra realtà quotidiana brulica di cose troppo piccole per essere viste, ma pur sempre enormi rispetto ai mattoni di cui è fatto il mondo, gli atomi e le molecole. Oltre ad essere alla radice di molte tecnologie di oggi e di domani, questi piccoli personaggi, ingredienti primari di quelli che gli scienziati chiamano "materiali soffici", "sistemi sovramolecolari", o " fluidi complessi", ci permettono anche di esplorare i segreti con cui la materia si organizza spontaneamente, perché anche la Vita altro non è se non l’apoteosi di questa incredibile "Terra di Mezzo", a metà strada tra le molecole e l’Uomo. Sfruttando l’esperienza scientifica accumulata dall’autore nel corso di molti anni, questo libro si propone di guidare il lettore attraverso un lungo, ma non troppo faticoso viaggio nel mondo delle nanoparticelle, dei...

  12. Humedales artificiales de flujo vertical para mejorar la calidad del agua del río Bogotá

    Directory of Open Access Journals (Sweden)

    T. Rodríguez Chaparro

    2005-01-01

    Full Text Available propósito de esta investigación consistió en evaluar la capacidad de reducción de compuestos orgánicos e inorgánicos en un humedal artificial de flujo vertical a escala laboratorio alimentado con agua del río Bogotá tomada a la altura del campus universitario “Río Grande” en Cajica para determinar la viabilidad de emplear este tipo de tecnología en control de la contaminación hídrica. El prototipo se diseño y construyo con base en las recomendaciones de autores como Arias (2003 y Cooper (1990 . Los resultados que se obtuvieron permitieron determinar reducciones de DBO205 = 37%, DQO = 10%, CT = 49%, ST = 16%, SST = 27% , NO2 = 83%, NO3 = 30% De lo anterior se concluye que a escala laboratorio el humedal artificial de flujo vertical mejora la calidad del agua del río Bogotá a la altura del campus “Río Grande” en Cajica

  13. The Impact of Cognitive Load on Operatic Singers’ Timing Performance.

    Directory of Open Access Journals (Sweden)

    Muzaffer eCorlu

    2015-04-01

    Full Text Available In the present paper, we report the results of an empirical study on the effects of cognitive load on operatic singing. The main aim of the study was to investigate to what extent a working memory task affected the timing of operatic singers’ performance. Thereby, we focused on singers’ tendency to speed up, or slow down their performance of musical phrases and pauses. Twelve professional operatic singers were asked to perform an operatic aria three times; once without an additional working memory task, once with a concurrent working memory task (counting shapes on a computer screen, and once with a relatively more difficult working memory task (more shapes to be counted appearing one after another. The results show that, in general, singers speeded up their performance under heightened cognitive load. Interestingly, this effect was more pronounced in pauses – more in particular longer pauses – compared to musical phrases. We discuss the role of sensorimotor control and feedback processes in musical timing to explain these findings.

  14. THE GALACTIC O-STAR SPECTROSCOPIC SURVEY (GOSSS). III. 142 ADDITIONAL O-TYPE SYSTEMS

    International Nuclear Information System (INIS)

    Apellániz, J. Maíz; Sota, A.; Alfaro, E. J.; Arias, J. I.; Barbá, R. H.; Walborn, N. R.; Simón-Díaz, S.; Herrero, A.; Negueruela, I.; Marco, A.; Leão, J. R. S.; Gamen, R. C.

    2016-01-01

    This is the third installment of the Galactic O-Star Spectroscopic Survey (GOSSS), a massive spectroscopic survey of Galactic O stars, based on new homogeneous, high signal-to-noise ratio, R  ∼ 2500 digital observations selected from the Galactic O-Star Catalog. In this paper, we present 142 additional stellar systems with O stars from both hemispheres, bringing the total of O-type systems published within the project to 590. Among the new objects, there are 20 new O stars. We also identify 11 new double-lined spectroscopic binaries, 6 of which are of O+O type and 5 of O+B type, and an additional new tripled-lined spectroscopic binary of O+O+B type. We also revise some of the previous GOSSS classifications, present some egregious examples of stars erroneously classified as O-type in the past, introduce the use of luminosity class IV at spectral types O4-O5.5, and adapt the classification scheme to the work of Arias et al.

  15. Mozart: the toothache of a genius.

    Science.gov (United States)

    Eramo, Stefano; Gallottini, Livio; Migliau, Guido

    2011-01-01

    The medical history of Wolfgang Amadeus Mozart (1756-1791) has been pieced together from his letters and from anecdotes, but his dental health is one aspect which has been somewhat overlooked. It is known that, from an early age, he suffered from toothache and tooth abscesses, problems that may even have had other medical repercussions. In this paper, the authors explore and consider whether these negative experiences might have influenced Mozart's work and his attitude to teeth and dental pathologies. Two pieces of evidence from the life and work of this great composer provide clues: the aria entitled "A tooth decayed and sensitive to cold" (KV 209 a) (1772), containing the lament of a "sick man" suffering from toothache; and the first of the "Zoroastrian Riddles," which Mozart proposed during a masked ball in 1786, and whose solution is "teeth." Close examination of these two creative feats demonstrate that Mozart's attitude toward dental pathologies was calm and rational, so much so that he even managed to use the topic as a source of inspiration for a small jewel of a composition.

  16. Simulation of the atmospheric dispersion at local scale in the area of Cogema (la Hague) using PERLE system

    International Nuclear Information System (INIS)

    Sandu, Irina; Lac, Christine

    2003-01-01

    METEO-FRANCE is presently developing a new system named PERLE which permits real time evaluation of atmospheric dispersion at local scale. This system consists in a non-hydrostatic meteorological model at mezo-scale (Meso-NH) and a particular code for the dispersion of the chemically passive pollutants. As a result of several studies performed by DP/SERV/ENV at Meteo-France, two particular codes have been retained for the dispersion module of PERLE: DIFPAR (EDF) and SPRAY (Aria Technologies). In this study, the dispersion at local scale of Kr 85 in the area of the nuclear-wastes reprocessing plant COGEMA (La Hague) has been simulated with the two dispersion models, initialised with the meteorological fields provided by Meso-NH. The simulations concern the most complete sampling campaign of Kr 85 performed in this area on 18th and 19th september 2001. The evaluation the two models performances and of the PERLE system's results for this campaign has been done by using the CTA (Atmospherical Transfer Coefficient) measured values. (authors)

  17. On the use of Cloud Computing and Machine Learning for Large-Scale SAR Science Data Processing and Quality Assessment Analysi

    Science.gov (United States)

    Hua, H.

    2016-12-01

    Geodetic imaging is revolutionizing geophysics, but the scope of discovery has been limited by labor-intensive technological implementation of the analyses. The Advanced Rapid Imaging and Analysis (ARIA) project has proven capability to automate SAR data processing and analysis. Existing and upcoming SAR missions such as Sentinel-1A/B and NISAR are also expected to generate massive amounts of SAR data. This has brought to the forefront the need for analytical tools for SAR quality assessment (QA) on the large volumes of SAR data-a critical step before higher-level time series and velocity products can be reliably generated. Initially leveraging an advanced hybrid-cloud computing science data system for performing large-scale processing, machine learning approaches were augmented for automated analysis of various quality metrics. Machine learning-based user-training of features, cross-validation, prediction models were integrated into our cloud-based science data processing flow to enable large-scale and high-throughput QA analytics for enabling improvements to the production quality of geodetic data products.

  18. THE GALACTIC O-STAR SPECTROSCOPIC SURVEY (GOSSS). III. 142 ADDITIONAL O-TYPE SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Apellániz, J. Maíz [Centro de Astrobiología, CSIC-INTA, campus ESAC, camino bajo del castillo s/n, E-28 692 Madrid (Spain); Sota, A.; Alfaro, E. J. [Instituto de Astrofísica de Andalucía-CSIC, Glorieta de la Astronomía s/n, E-18 008 Granada (Spain); Arias, J. I.; Barbá, R. H. [Departamento de Física, Universidad de La Serena, Av. Cisternas 1200 Norte, La Serena (Chile); Walborn, N. R. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21 218 (United States); Simón-Díaz, S.; Herrero, A. [Instituto de Astrofísica de Canarias, E-38 200 La Laguna, Tenerife (Spain); Negueruela, I.; Marco, A. [DFISTS, EPS, Universidad de Alicante, carretera San Vicente del Raspeig s/n, E-03 690 Alicante (Spain); Leão, J. R. S. [Univ. Federal do Rio Grande do Norte—UFRN, Caixa Postal 1524, CEP 59 078-970, Natal—RN (Brazil); Gamen, R. C., E-mail: jmaiz@cab.inta-csic.es [Instituto de Astrofísica de La Plata (CONICET, UNLP), Paseo del Bosque s/n, 1900 La Plata (Argentina)

    2016-05-01

    This is the third installment of the Galactic O-Star Spectroscopic Survey (GOSSS), a massive spectroscopic survey of Galactic O stars, based on new homogeneous, high signal-to-noise ratio, R  ∼ 2500 digital observations selected from the Galactic O-Star Catalog. In this paper, we present 142 additional stellar systems with O stars from both hemispheres, bringing the total of O-type systems published within the project to 590. Among the new objects, there are 20 new O stars. We also identify 11 new double-lined spectroscopic binaries, 6 of which are of O+O type and 5 of O+B type, and an additional new tripled-lined spectroscopic binary of O+O+B type. We also revise some of the previous GOSSS classifications, present some egregious examples of stars erroneously classified as O-type in the past, introduce the use of luminosity class IV at spectral types O4-O5.5, and adapt the classification scheme to the work of Arias et al.

  19. How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA(2) LEN statement

    DEFF Research Database (Denmark)

    Bousquet, J; Schünemann, H J; Bousquet, P J

    2011-01-01

    and pharmacotherapy should be considered separately for several reasons, as developed in this study. These include the severity and persistence of allergic rhinitis in the patients enrolled in the study, the problem of the placebo, allergen exposure (in particular pollen and mite), the analysis and reporting...... of RCTs in sublingual immunotherapy. It is not possible to directly extrapolate the rules or parameters used in medication RCTs to SIT. It also provides some suggestions for the research that will be needed. Interestingly, some of the research questions can be approached with the available data obtained...

  20. Ocorrência de Cryptosporidium spp. e outros parasitas em hortaliças consumidas in natura, no Recife Occurrence of Cryptosporidium spp. and others parasites in vegetables consumed in natura, Recife, Brazil

    Directory of Open Access Journals (Sweden)

    Celiane Gomes Maia da Silva

    2005-12-01

    Full Text Available O objetivo deste estudo foi verificar a ocorrência de enteroparasitas em hortaliças comercializadas e consumidas em Pernambuco. Foram utilizadas 100 amostras de hortaliças: 40 amostras de alface lisa (Lactuca sativa, 40 de agrião (Nasturtium officinale e 20 de acelga (Beta vulgaris, provenientes de feiras livres e supermercados. A detecção de Cryptosporidium spp. foi realizada conforme Monge e Arias sendo utilizado dois métodos de coloração, Koster modificado e Ziehl-Nielsen. Foi usada a técnica de sedimentação espontânea de Gelli et al. para a análise parasitológica. As análises de coliformes totais e Escherichia coli foram realizadas de acordo com Andrews. Os resultados obtidos mostraram um percentual de contaminação parasitária em 60% de alface, 30% de agrião e 20% de acelga, destacando-se o Ascaris lumbricoides, Strongyloides stercoralis e Ancylostoma duodenale dentre os helmintos, e o Cryptosporidium spp., Entamoeba coli e o complexo Entamoeba histolytica/Entamoeba díspar, dentre os protozoários com maior freqüência. As hortaliças mais contaminadas por coliformes totais e Escherichia coli foram alface nas amostras de supermercado e agrião em feira livre. Esses dados sugerem a necessidade da adoção de medidas educativas aos produtores, e do monitoramento das águas destinadas à irrigação das hortas.The study was carried with the aim to evaluate the occurrence of enteroparasites in vegetables commercialized and consumed in natural form in the state of Pernambuco, Brazil. Horticultural samples purchased from supermarket and free market: 40 from lettuce (Lactuca sativa, 40 from watercress (Nasturtium officinale and 20 from chard (Beta vulgaris were analyzed. Cryptosporidium spp. detection was realized following Monge and Arias methodology, using two staining processes (Koster modified and Ziehl-Nielsen. Parasitological analysis was determined by the spontaneous sedimentation technique (Gelli et al., and total

  1. Heroe, Egregio, para contrabaixo e cravo: aspectos didáticos e interpretativos em uma transcrição de uma cantata do repertório colonial brasileiro Heroe, Egregio for double and harpsichord: interpretive and pedagogical aspects in a transcription of a cantata from the Brazilian colonial repertory

    Directory of Open Access Journals (Sweden)

    Fausto Borém

    2008-12-01

    Full Text Available O ainda restrito acesso a partituras e concertos do vasto repertório musical brasileiro dos séculos XVIII e XIX e sua instrumentação estereotipada (quase sempre obras vocais religiosas com acompanhamento orquestral são obstáculos para sua inclusão nos currículos dos cursos de música no país e sua apreciação por um público mais amplo. Uma alternativa para mudar este quadro é a transcrição de obras desse repertório e adaptação de sua instrumentação para grupos de câmara menores, com exclusão até mesmo da voz na sua instrumentação. Essas transcrições podem proporcionar, de maneira mais eficaz, o contato e a experimentação com as assim-chamadas práticas de performance historicamente informadas (Historically Informed Performance ou HIP, seja a partir da adaptação de referências (auditivas e textuais já consolidadas na interpretação do repertório europeu, seja a partir da análise de elementos históricos, formais e possíveis figuras de retórica. No presente trabalho, estas questões são abordadas no Recitativo e Aria da cantata acadêmica Heroe, egregio, douto, peregrino (anônimo, Salvador, 1759 para soprano, dois violinos e baixo contínuo, transcrita para um instrumento de cordas orquestral solista (violino, viola, violoncelo ou contrabaixo e cravo.The still limited access to scores and concerts of the vast Brazilian music repertoire from the eighteenth and nineteenth centuries and its stereotyped instrumentation (almost always sacred vocal music with orchestral accompaniment are obstacles for the inclusion of this repertory in the country's instrumental music curricula and its appreciation by a wider audience. An alternative for this situation is the transcription of works and change of their instrumentation to fit smaller chamber formations, including those without singing. Moreover, these transcriptions could also allow the contact and experimentation with the so-called Historically Informed Performance

  2. Ranibizumab in the treatment of choroidal neovascularization on the border of an inferior staphyloma associated with tilted disc syndrome

    Directory of Open Access Journals (Sweden)

    Luis Arias

    2010-03-01

    Full Text Available Luis Arias1,2, Jordi Monés21Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona; 2Institut de la Màcula i de la Retina, Centro Médico Teknon, BarcelonaPurpose: To describe a case of choroidal neovascularization (CNV on the border of an inferior staphyloma associated with tilted disc syndrome treated with intravitreal ranibizumab.Patients: Observational case report.Methods: A patient with CNV on the border of an inferior staphyloma associated with tilted disc syndrome was imaged using fluorescein angiography, autofluorescence and spectral domain optical coherence tomography, and treated with intravitreal injections of ranibizumab. Results: The patient received 3 ranibizumab injections during the 9-month follow-up. The visual acuity improved from 20/40 to 20/32 and the foveal thickness reduced from 470 microns to 248 microns. The angiograms showed resolution of leakage associated with CNV. There were no adverse events.Conclusion: Intravitreal ranibizumab is an efficacious and safe treatment in the management of choroidal neovascularization on the border of an inferior staphyloma associated with tilted disc syndrome.Keywords: intravitreal ranibizumab, choroidal neovascularization, tilted disc syndrome, inferior staphyloma

  3. Rupture dynamics and ground motions from earthquakes in 2-D heterogeneous media

    KAUST Repository

    Bydlon, Samuel A.

    2015-03-21

    ©2015. American Geophysical Union. All Rights Reserved. We perform 2-D simulations of earthquakes on rough faults in media with random heterogeneities (with von Karman distribution) to study the effects of geometric and material heterogeneity on the rupture process and resulting high-frequency ground motions in the near-fault region (out to ∼20km). Variations in slip and rupture velocity can arise from material heterogeneity alone but are dominantly controlled by fault roughness. Scattering effects become appreciable beyond ∼3km from the fault. Near-fault scattering extends the duration of incoherent, high-frequency ground motions and, at least in our 2-D simulations, elevates root-mean-square accelerations (i.e., Arias intensity) with negligible reduction in peak velocities. We also demonstrate that near-fault scattering typically occurs in the power law tail of the power spectral density function, quantified by the Hurst exponent and another parameter combining standard deviation and correlation length. Key Points Fault roughness, not material heterogeneity, dominates rupture process Introduce parameter that can be used to quantify near-fault scattering Scattering affects the duration and amplitude of high-frequency ground motions

  4. Pulsa o coração da cidade: errâncias, afectos e potências no dia e na noite da Praça do Ferreira

    Directory of Open Access Journals (Sweden)

    Alice Dote

    2017-12-01

    Full Text Available O presente artigo aborda a potência dos usos, contra-usos e modos de habitar dos artistas de rua da Praça do Ferreira, na cidade de Fortaleza, Ceará. O trabalho apoia-se nos percursos e nas errâncias urbanas da vivência na e da Praça do Ferreira em diferentes temporalidades (diurna e noturna, especialmente no contexto de apresentações noturnas do Grupo As 10 Graças de Palhaçaria aos moradores da Praça. Através desses que têm a rua como casa, agem pelas brechas e proliferam-se pelas margens, proponho-me a perceber a potência da arte de rua, do encontro e da experiência de alteridade na Praça do Ferreira. Finalizo o texto apontando que esse local, assim ocupado, se impregna de significados outros e revela-se como um território de criação, de inventividade, de existência e resistência, portanto, de potência de vida que é, em si, potência política. Palavras-chave: Praça do Ferreira; Fortaleza; cidade; arte urbana; artista de rua

  5. STUDY OF A PROTOCOL FOR MEASURING SAIL SPORTS TRAINING

    Directory of Open Access Journals (Sweden)

    Claudio Scotton

    2015-04-01

    Full Text Available Durante l’attività agonistica i velisti incontrano molteplici difficoltà. Elenchiamo solo alcune variabili ambientali che condizionano le scelte tattiche e tecniche che possono rivelarsi vincenti o perdenti (Scotton 2007: vento, onda, corrente, umidità, temperatura dell’acqua e dell’aria, distanza del campo di regata dalla sistemazione degli atleti a terra, sole, pioggia. Da tutto ciò si evince che la Vela, rispetto ad altre specialità sportive praticate in una condizione stabile come accade in una palestra o in un campo di atletica e caratterizzate dalla prevalenza di abilità motorie sportive stereotipate (Scotton 2003, naviga, vocabolo pertinente, con maggiori difficoltà nell’individuare i carichi di lavoro interno ed esterno. Obiettivo: Scopo del presente studio è l’indagine conoscitiva delle caratteristiche antropometriche di base e di alcune capacità organico-muscolari e coordinative di velisti della classe 29er; deriva in doppio acrobatica giovanile (Federvela 2008, molto veloce in qualsiasi condizione, ma anche instabile e difficile da condurre. Il lavoro ha permesso di gettare le basi per la messa punto di un protocollo di misurazione dell’allenamento applicabile alla Vela.

  6. Arte participativo. El trabajo como (auto representación

    Directory of Open Access Journals (Sweden)

    Ana Amado

    2010-12-01

    Full Text Available El “giro social” contemporáneo del documentalismo audiovisual y de las performances teatrales, plantea una serie de cuestiones éticas y también estéticas alrededor de las formas artísticas vueltas a la representación del padecimiento de los pueblos. Con diferentes variantes, se tiende a conceder a las identidades subalternas el centro de la escena, o de un espacio de exhibición determinado, donde explican o desempeñan acciones de acuerdo a sus respectivas experiencias, sean estas de clase, de género, de edad, sexualidad, pero que en la última década están cada vez más concentradas en el mundo del trabajo o en las consecuencias de su crisis. Los apuntes que siguen abordan esta cuestión y sus paradojas a través de la revisión de algunas experiencias argentinas recientes, entre ellas la película Estrellas, de Federico León y las intervenciones teatrales “Mucamas de hotel” de Lola Arias y “Fábrica”, de Gerardo Neuman.

  7. Role of Predatory Mites in Persistent Nonoccupational Allergic Rhinitis

    Directory of Open Access Journals (Sweden)

    Paloma Poza Guedes

    2016-01-01

    Full Text Available Mites can sensitize and induce atopic disease in predisposed individuals and are an important deteriorating factor in patients with allergic rhinitis, asthma, and atopic dermatitis. Although Pyroglyphidae mites have been extensively studied, very scarce reports are available on Cheyletidae spp. especially regarding human respiratory pathology. The main objective of the present study is to investigate the clinical role of this predator mite (Cheyletus eruditus as a respiratory antigen in a selected sensitized human population. Fifty-two adult patients were recruited from the outpatient allergy clinic to assess their eligibility for the study. The thirty-seven subjects with persistent allergic rhinitis (PAR who fulfilled the ARIA criteria had a positive IgE response confirmed by skin prick test (SPT to C. eruditus. Only those individuals (37/47 with a positive SPT to C. eruditus showed a positive nasal provocation test (NPT, while 10 patients with nonallergic mild-to-moderate persistent rhinitis, control group, had a negative NPT with C. eruditus. The present paper describes a new role for the predator mite Cheyletus eruditus as a respiratory allergen in a selected subset of patients in a subtropical environment afflicted with persistent nonoccupational allergic rhinitis.

  8. The impact of soil suction variation on earthquake intensity indices

    Directory of Open Access Journals (Sweden)

    Biglari Mahnoosh

    2016-01-01

    Full Text Available Soil properties can completely change the ground motion characteristics as they travel from the bedrock to the surface because, soil as a low-pass filter, may amplify or deamplify seismic motions in some frequencies on the wave travelling path. Recent studies about the advanced unsaturated soil mechanics clearly shows that dynamic properties of soils, including small-strain shear modulus (Gmax, shear modulus reduction (G/Gmax, and damping ratio (D curves are affected by changes in the soil suction level. The current study present nonlinear time-dependent analysis of three different unsaturated soils available in the literature with different ranges of nonlinear behaviour that earlier have been studied on unsaturated dynamic models. Since, the earthquake intensity parameters can be used to describe the damage potential of an earthquake, the focus of this paper is to evaluate the impact of the suction variation on the engineering ground motion parameters, including peak values of strong motion, Vmax/Amax, root-mean-square acceleration, Arias intensity, characteristic intensity, cumulative absolute velocity, acceleration spectrum intensity, effective design acceleration, A95 parameter and predominant period separately under the near-field and the far-field seismicity categories.

  9. Por los caminos de Sodoma. Discurso de réplica, promesa formativa para una homosexualidad otra (1932

    Directory of Open Access Journals (Sweden)

    Alexánder Hincapié García

    2011-12-01

    Full Text Available [PDF]InicioRevista No 41- Por los caminos de Sodoma. Discurso de réplica, promesa formativa para una homosexualidad otra (1932[*]Alexánder Hincapié García[**]DossierRESUMENEl presente trabajo realiza una lectura de la novela Por los caminos de Sodoma: confesiones íntimas de un homosexual, publicada en 1932, de Sir Edgar Dixon; seudónimo utilizado por el intelectual caldense Bernardo Arias Trujillo. La tesis que proponemos refiere que el gesto literario que presenta a la homosexualidad en los años treinta, desde la toma de la palabra de los sujetos constituidos como homosexuales, supone el ejercicio de un discurso de réplica (o contradiscurso que, a pesar del signo trágico de sus personajes, inaugura la promesa formativa de una homosexualidad otra para aquellos sujetos portadores de las marcas de la injuria y la degradación. El artículo está dividido en tres apartados que abordan la relación entre literatura y formación, la homosexualidad como discurso de réplica y, para concluir, la novela Por los caminos de Sodoma entendida como un alegato.

  10. MENTAL ILLNESS IN THE VIEW OF PSYCHOTIC INDIVIDUALS: THEIR LINES AND GRAPHIC REPRESENTATIONS

    Directory of Open Access Journals (Sweden)

    Danieli Gasparini

    2013-02-01

    Full Text Available Objetivo: conhecer os significados da doença mental para indivíduos com enfermidades psicóticas, internados em um hospital geral. Metodologia: estudo descritivo com abordagem qualitativa. Constituíram a amostra cinco pessoas. Foi utilizada entrevista semi-estruturada e representação gráfica para obtenção das informações. Os dados foram submetidos à análise do conteúdo, do tipo temática. Resultados e Discussão: os pesquisados se reportaram à doença mental, como resultado de castigos divinos e da feitiçaria; realidade carregada de sofrimento e dificuldades; fruto de perdas sofridas e de vivências da infância; algo difícil de explicar, carregado de estigma, incompreensão, descrédito e desqualificação; presença de sintomas; limitadora para as atividades cotidianas e incapacitante para o trabalho. Conclusão: conclui-se que há necessidade de intervenções que ultrapassem a redução e controle de sintomas, dirigindo um olhar para as relações do doente mental com família, trabalho e comunidade.

  11. El relato de la memoria en el teatro de Buenos Aires

    Directory of Open Access Journals (Sweden)

    Silvina Díaz

    2016-07-01

    Full Text Available La recuperación de la memoria y el testimonio se han convertido en un requerimiento vital luego de la más cruenta dictadura militar argentina, que tuvo lugar entre 1976 y 1983. Los traumas históricos acarreados y las profundas heridas, individuales y colectivas, dieron lugar a innumerables hechos culturales. Nos proponemos analizar dos modos diversos, dentro de la dramaturgia de la posdictadura, de narrar la problemática de la represión y los desaparecidos, como paradigmas de toda una tendencia de textos que consideran al teatro como un instrumento de indagación social y política. La obra de Lola Arias recurre a un lenguaje referencial y explícito –propio del teatro político–, aun cuando contenga una importante carga simbólica, mientras que los textos de Omar Pacheco manifiestan la crisis del relato dramático tradicional y de la noción restrictiva que considera a la palabra únicamente en su dimensión psicologista y semántica, para destacar en cambio su materialidad y su opacidad sígnica.

  12. Open stack thermal battery tests

    Energy Technology Data Exchange (ETDEWEB)

    Long, Kevin N. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Christine C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Grillet, Anne M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Headley, Alexander J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Fenton, Kyle [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wong, Dennis [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ingersoll, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-04-17

    We present selected results from a series of Open Stack thermal battery tests performed in FY14 and FY15 and discuss our findings. These tests were meant to provide validation data for the comprehensive thermal battery simulation tools currently under development in Sierra/Aria under known conditions compared with as-manufactured batteries. We are able to satisfy this original objective in the present study for some test conditions. Measurements from each test include: nominal stack pressure (axial stress) vs. time in the cold state and during battery ignition, battery voltage vs. time against a prescribed current draw with periodic pulses, and images transverse to the battery axis from which cell displacements are computed. Six battery configurations were evaluated: 3, 5, and 10 cell stacks sandwiched between 4 layers of the materials used for axial thermal insulation, either Fiberfrax Board or MinK. In addition to the results from 3, 5, and 10 cell stacks with either in-line Fiberfrax Board or MinK insulation, a series of cell-free “control” tests were performed that show the inherent settling and stress relaxation based on the interaction between the insulation and heat pellets alone.

  13. Earthquake Intensity and Strong Motion Analysis Within SEISCOMP3

    Science.gov (United States)

    Becker, J.; Weber, B.; Ghasemi, H.; Cummins, P. R.; Murjaya, J.; Rudyanto, A.; Rößler, D.

    2017-12-01

    Measuring and predicting ground motion parameters including seismic intensities for earthquakes is crucial and subject to recent research in engineering seismology.gempa has developed the new SIGMA module for Seismic Intensity and Ground Motion Analysis. The module is based on the SeisComP3 framework extending it in the field of seismic hazard assessment and engineering seismology. SIGMA may work with or independently of SeisComP3 by supporting FDSN Web services for importing earthquake or station information and waveforms. It provides a user-friendly and modern graphical interface for semi-automatic and interactive strong motion data processing. SIGMA provides intensity and (P)SA maps based on GMPE's or recorded data. It calculates the most common strong motion parameters, e.g. PGA/PGV/PGD, Arias intensity and duration, Tp, Tm, CAV, SED and Fourier-, power- and response spectra. GMPE's are configurable. Supporting C++ and Python plug-ins, standard and customized GMPE's including the OpenQuake Hazard Library can be easily integrated and compared. Originally tailored to specifications by Geoscience Australia and BMKG (Indonesia) SIGMA has become a popular tool among SeisComP3 users concerned with seismic hazard and strong motion seismology.

  14. ACPYPE - AnteChamber PYthon Parser interfacE.

    Science.gov (United States)

    Sousa da Silva, Alan W; Vranken, Wim F

    2012-07-23

    ACPYPE (or AnteChamber PYthon Parser interfacE) is a wrapper script around the ANTECHAMBER software that simplifies the generation of small molecule topologies and parameters for a variety of molecular dynamics programmes like GROMACS, CHARMM and CNS. It is written in the Python programming language and was developed as a tool for interfacing with other Python based applications such as the CCPN software suite (for NMR data analysis) and ARIA (for structure calculations from NMR data). ACPYPE is open source code, under GNU GPL v3, and is available as a stand-alone application at http://www.ccpn.ac.uk/acpype and as a web portal application at http://webapps.ccpn.ac.uk/acpype. We verified the topologies generated by ACPYPE in three ways: by comparing with default AMBER topologies for standard amino acids; by generating and verifying topologies for a large set of ligands from the PDB; and by recalculating the structures for 5 protein-ligand complexes from the PDB. ACPYPE is a tool that simplifies the automatic generation of topology and parameters in different formats for different molecular mechanics programmes, including calculation of partial charges, while being object oriented for integration with other applications.

  15. New ways of insulin delivery.

    Science.gov (United States)

    Heinemann, L

    2011-02-01

    The predominant number of papers published from the middle of 2009 to the middle of 2010 about alternative routes of insulin administration (ARIA) were still about inhaled insulin. Long-term experience with Exubera was the topic of a number of publications that are also of relevance for inhaled insulin in general. The clinical trials performed with AIR insulin by Eli Lilly were published in a supplement issue of one diabetes technology journal and most of these will be presented. A number of other publications (also one in a high ranked journal) about their inhaled insulin were from another company: MannKind. The driving force behind Technosphere insulin (TI) - which is the only one still in clinical development - is Al Mann; he has put a lot of his personal fortune in this development. We will know the opinion of the regulatory authorities about TI in the near future; however, I am personally relatively confident that the Food and Drug Administration will provide TI with market approval. The more critical question for me is: will diabetologists and patients jump on this product once it becomes commercially available? Will it become a commercial success? In view of many negative feelings in the scientific community about inhaled insulin, it might be of help that MannKind publish their studies with TI systematically. Acknowledging being a believer in this route of insulin administration myself, one has to state that Exubera and AIR insulin had not offered profound advantages in terms of pharmacokinetic (PK) and pharmacodynamic (PD) properties in comparison with subcutaneously (SC) applied regular human insulin (RHI) and rapid-acting insulin analogues. The time-action profiles of these inhaled insulins were more or less comparable with that of rapid-acting insulin analogues. This is clearly different with TI which exhibits a strong metabolic effect shortly after application and a rapid decline in the metabolic effect thereafter; probably the duration of action is

  16. Rough Precipitation Forecasts based on Analogue Method: an Operational System

    Science.gov (United States)

    Raffa, Mario; Mercogliano, Paola; Lacressonnière, Gwendoline; Guillaume, Bruno; Deandreis, Céline; Castanier, Pierre

    2017-04-01

    In the framework of the Climate KIC partnership, has been funded the project Wat-Ener-Cast (WEC), coordinated by ARIA Technologies, having the goal to adapt, through tailored weather-related forecast, the water and energy operations to the increased weather fluctuation and to climate change. The WEC products allow providing high quality forecast suited in risk and opportunities assessment dashboard for water and energy operational decisions and addressing the needs of sewage/water distribution operators, energy transport & distribution system operators, energy manager and wind energy producers. A common "energy water" web platform, able to interface with newest smart water-energy IT network have been developed. The main benefit by sharing resources through the "WEC platform" is the possibility to optimize the cost and the procedures of safety and maintenance team, in case of alerts and, finally to reduce overflows. Among the different services implemented on the WEC platform, ARIA have developed a product having the goal to support sewage/water distribution operators, based on a gradual forecast information system ( at 48hrs/24hrs/12hrs horizons) of heavy precipitation. For each fixed deadline different type of operation are implemented: 1) 48hour horizon, organisation of "on call team", 2) 24 hour horizon, update and confirm the "on call team", 3) 12 hour horizon, secure human resources and equipment (emptying storage basins, pipes manipulations …). More specifically CMCC have provided a statistical downscaling method in order to provide a "rough" daily local precipitation at 24 hours, especially when high precipitation values are expected. This statistical technique consists of an adaptation of analogue method based on ECMWF data (analysis and forecast at 24 hours). One of the most advantages of this technique concerns a lower computational burden and budget compared to running a Numerical Weather Prediction (NWP) model, also if, of course it provides only this

  17. Studies in Astronomical Time Series Analysis. VI. Bayesian Block Representations

    Science.gov (United States)

    Scargle, Jeffrey D.; Norris, Jay P.; Jackson, Brad; Chiang, James

    2013-01-01

    This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time suppressing the inevitable corrupting observational errors. We present a simple nonparametric modeling technique and an algorithm implementing it-an improved and generalized version of Bayesian Blocks [Scargle 1998]-that finds the optimal segmentation of the data in the observation interval. The structure of the algorithm allows it to be used in either a real-time trigger mode, or a retrospective mode. Maximum likelihood or marginal posterior functions to measure model fitness are presented for events, binned counts, and measurements at arbitrary times with known error distributions. Problems addressed include those connected with data gaps, variable exposure, extension to piece- wise linear and piecewise exponential representations, multivariate time series data, analysis of variance, data on the circle, other data modes, and dispersed data. Simulations provide evidence that the detection efficiency for weak signals is close to a theoretical asymptotic limit derived by [Arias-Castro, Donoho and Huo 2003]. In the spirit of Reproducible Research [Donoho et al. (2008)] all of the code and data necessary to reproduce all of the figures in this paper are included as auxiliary material.

  18. STUDIES IN ASTRONOMICAL TIME SERIES ANALYSIS. VI. BAYESIAN BLOCK REPRESENTATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Scargle, Jeffrey D. [Space Science and Astrobiology Division, MS 245-3, NASA Ames Research Center, Moffett Field, CA 94035-1000 (United States); Norris, Jay P. [Physics Department, Boise State University, 2110 University Drive, Boise, ID 83725-1570 (United States); Jackson, Brad [The Center for Applied Mathematics and Computer Science, Department of Mathematics, San Jose State University, One Washington Square, MH 308, San Jose, CA 95192-0103 (United States); Chiang, James, E-mail: jeffrey.d.scargle@nasa.gov [W. W. Hansen Experimental Physics Laboratory, Kavli Institute for Particle Astrophysics and Cosmology, Department of Physics and SLAC National Accelerator Laboratory, Stanford University, Stanford, CA 94305 (United States)

    2013-02-20

    This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time suppressing the inevitable corrupting observational errors. We present a simple nonparametric modeling technique and an algorithm implementing it-an improved and generalized version of Bayesian Blocks-that finds the optimal segmentation of the data in the observation interval. The structure of the algorithm allows it to be used in either a real-time trigger mode, or a retrospective mode. Maximum likelihood or marginal posterior functions to measure model fitness are presented for events, binned counts, and measurements at arbitrary times with known error distributions. Problems addressed include those connected with data gaps, variable exposure, extension to piecewise linear and piecewise exponential representations, multivariate time series data, analysis of variance, data on the circle, other data modes, and dispersed data. Simulations provide evidence that the detection efficiency for weak signals is close to a theoretical asymptotic limit derived by Arias-Castro et al. In the spirit of Reproducible Research all of the code and data necessary to reproduce all of the figures in this paper are included as supplementary material.

  19. Avaliação da Sustentabilidade da Madeira por Meio da Ferramenta ISMAS

    Directory of Open Access Journals (Sweden)

    Márcia Bissoli-Dalvi

    2017-10-01

    Full Text Available RESUMO Esta pesquisa objetivou avaliar o índice de sustentabilidade da madeira usada na construção civil a partir dos critérios previamente estabelecidos na ferramenta ISMAS – Instrumento para Seleção de Materiais Mais Sustentáveis, cuja metodologia considera especificamente os aspectos relacionados à “economia de matérias-primas” e “geração e gestão de resíduos” nos procedimentos de avaliação. A ferramenta apresenta a seguinte escala de graduação para os possíveis resultados: muito baixo, baixo, médio, alto e elevado. A metodologia adotada para a obtenção dos resultados foi estabelecida a partir de testes com o instrumento, envolvendo arquitetos sediados no Estado do Espírito Santo, Brasil. O resultado demonstrou que a madeira obteve o índice “alto” de sustentabilidade, contrariando a hipótese inicial de que o material alcançaria o nível “elevado”. Esse resultado sugere o amadurecimento do conceito sustentável da madeira, que atualmente relaciona-se somente com o critério renovável. A avaliação pelo ISMAS demonstrou a necessidade do uso de outros critérios.

  20. ACPYPE - AnteChamber PYthon Parser interfacE

    Directory of Open Access Journals (Sweden)

    Sousa da Silva Alan W

    2012-07-01

    Full Text Available Abstract Background ACPYPE (or AnteChamber PYthon Parser interfacE is a wrapper script around the ANTECHAMBER software that simplifies the generation of small molecule topologies and parameters for a variety of molecular dynamics programmes like GROMACS, CHARMM and CNS. It is written in the Python programming language and was developed as a tool for interfacing with other Python based applications such as the CCPN software suite (for NMR data analysis and ARIA (for structure calculations from NMR data. ACPYPE is open source code, under GNU GPL v3, and is available as a stand-alone application at http://www.ccpn.ac.uk/acpype and as a web portal application at http://webapps.ccpn.ac.uk/acpype. Findings We verified the topologies generated by ACPYPE in three ways: by comparing with default AMBER topologies for standard amino acids; by generating and verifying topologies for a large set of ligands from the PDB; and by recalculating the structures for 5 protein–ligand complexes from the PDB. Conclusions ACPYPE is a tool that simplifies the automatic generation of topology and parameters in different formats for different molecular mechanics programmes, including calculation of partial charges, while being object oriented for integration with other applications.

  1. Towards the use of radon distribution in schools as a health indicator

    International Nuclear Information System (INIS)

    Milu, C.; Gheorghe, R.; Dumitrescu, A.

    2006-01-01

    A pilot study concerning indoor radon and gamma dose measurements in school and kindergarten was performed in Bucharest metropolitan area, within a bilateral cooperation between the Institute of Public Health, Bucharest, Romania, and Joszef Stefan Institute, Ljubliana, Slovenia. One hundred schools and kindergartens were included in this study. Because the geological structure of Bucharest subsoil is the same for whole selected aria (a loess platform), the school selection criteria were the age of buildings and the type of building materials. Indoor radon concentrations were measured with nuclear track detectors one month, during the winter. The data have presented a lognormal distribution in the range of (43:477). An arithmetic mean of 146 Bq/m 3 and a geometric mean of 128.18 Bq/m 3 were obtained. Concomitant with indoor radon measurements, gamma dose rate measurement carried out, using thermoluminescence dosimeters. The results ranged from 65.51 to 127.45 n Sv/hour, with a mean of 91.1141(SD12.22) n Sv/mouth and a geometric mean of 90.31 n Sv/hour. The obtained results merely show a preliminary picture of indoor radon and gamma levels in schools and kindergarten from Bucharest and as such a good base for a national monitoring program. (authors)

  2. A feasibility study on active solar space heating technology for office buildings in Greece

    Directory of Open Access Journals (Sweden)

    Letiane Benincá

    2017-12-01

    Full Text Available Este artigo explora a viabilidade de utilizar coletores solares térmicos com capacidade de armazenamento e radiadores convencionais para aquecimento de edifícios de escritórios na Grécia. Um modelo dinâmico de simulação na ferramenta ESP-r é utilizado para analisar o desempenho do sistema de coleta solar integrado ao edifício para diferentes perfis de demanda em todas as zonas climáticas da Grécia. O impacto da capacidade do sistema de armazenamento, a área do coletor e o ângulo de inclinação são investigados quanto ao desempenho geral do sistema. Os escritórios na Grécia se enquadram em vários cenários de demanda anual, determinados pela orientação do edifício, a localização e a exposição ao ambiente externo. Finalmente, uma tentativa é feita para extrapolar as descobertas para todo o estoque de escritórios da Grécia. A partir desse ponto, utilizando o sistema de aquecimento de energia solar ativo proposto, a economia de energia térmica alcançaria 29% no total devido à cobertura solar.

  3. La potencialidad turística del patrimonio geológico-minero del Parque Natural Sierra de Aracena y Picos de Aroche (Huelva. España

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    Ramón Garrido Morillo

    2004-01-01

    Full Text Available La tendencia actual en la Unión Europea muestra la creciente puesta en valor de los espacios naturales protegidos como un elemento fundamental en los proyectos de desarrollo para el medio rural. Los Planes de Desarrollo Sostenible son ejemplos de estos elementos donde se trata de compaginar la conservación con el desarrollo de acuerdo con la tendencia actual de la Unión europea y la cumbre internacional de Río de Janeiro. El Parque Natural Sierra de Aracena y Picos de Aroche posee múltiples recursos turísticos, tanto naturales como culturales, estos últimos en todas sus modalidades: arqueológicos, arquitectónicos, etnológicos, geológicos, mineros, etc. El proceso orogénicos de sierra Morena ha dado lugar a formaciones geológicas de importante carácter turístico, siendo la más destacada la Gruta de las Maravillas en Aracena, punto de concentración de la mayor parte del turismo del Parque. Cabe destacar también algunos afloramientos como los de la Peña de Arias Montano, pero existen otros puntos que requieren de su puesta en valor con fines turísticos

  4. Introduction

    Directory of Open Access Journals (Sweden)

    Helge Hvid

    2016-12-01

    Full Text Available In this issue, four articles are published. Corin and Björk present a study of the psychosocial work environment among managers in public schools and in public elder care in Sweden. The study provides new insight into the working conditions of managers in the public sector, and at the same time, the study contributes to the development of research methods in the field. The study is based on Demerouti and Bakkers’ Job Demand-Resource model, which summarizes several well-known models for the studying of psychosocial work environment, primarily the Demand Control model of Karasek and Theorell and the Efford Reward model of Siegrist. The Job Demand-Resource model is most often used in survey studies, where employees assess their working conditions in a questionnaire. Corin and Björk, meanwhile, use the model as a basis for a qualitative study, which forms an external assessment of job demands and job resources. They use the ARIA method, based on the German ‘activity theory’. The study suggests that there is a strong imbalance between demands and resources in managers' work and the study illustrates how surveys and qualitative studies could be combined in a fruitful way (...

  5. Bolsa Família e assimetrias de gênero: reforço ou mitigação?

    Directory of Open Access Journals (Sweden)

    Luana Passos

    Full Text Available Resumo Este artigo tem por objetivo investigar se o programa Bolsa Família contribui para o processo de individualização das mulheres pobres. Para tanto, foi utilizada a técnica de pareamento por escore de propensão, a fim de identificar mulheres e homens não atendidos pelo programa comparáveis a mulheres e homens atendidos. Com base na Pesquisa Nacional por Amostra de Domicílio de 2006, estimaram-se a jornada de trabalho doméstico, a participação no mercado de trabalho e as horas de trabalho remunerado de homens e mulheres. Os resultados não foram conclusivos para participação no mercado de trabalho. Para a jornada de trabalho remunerado, há indícios de que o Programa Bolsa Família reduza as horas trabalhadas de homens e mulheres. Para a jornada de trabalho doméstico, há indicativos de aumento de tempo de cuidado doméstico para mulheres e redução para homens. Os resultados da pesquisa sugerem que o programa reforçaria papéis tradicionais de gênero, não contribuindo para a individualização das mulheres pobres.

  6. Experimental evaluation of the oxygen transfer in bubble aeration systems. Full scale experiences in lengthened activated sludge reactors; Valutazione sperimantale del trasferimento dell'ossigeno in sistemi di aerazione a bolle fini. Esperienza a scala reale in reattori a fanghi attivi a forma allungata

    Energy Technology Data Exchange (ETDEWEB)

    Andreottola, G.; Ragazzi, M.; Tatano, F. [Trento Univ. (Italy). Dipt. di Ingegneria Civile. Ist. di Ingegneria Sanitaria-Ambientale

    1999-06-01

    The results of some full-scale oxygen transfer measurements conduced at the lengthened activate sludge tanks of two WWTPs of Trentino Region, are presented and discussed. As far at the tests in clean water are concerned, the non-liner regression method seems non accurate; important conclusion on the correlation between oxygen transfer process and typical parameters (i.e., fine-bubble diffusers, specific air flux) are derived. As far as the test in the wastewater is concerned, an increase of {alpha}-value from the inlet to the end of aeration tanks has been observed in the 'Andalo' WWTP. [Italian] Vengono presentati e discussi i risultati di alcune prove di ossigenazione a scala reale condotte presso due impianti di depurazione del Trentino. Con riferimento alle prove di acqua pulita, il metodo di elaborazione dati tramite regressione non lineare ai minimi quadrati e' apparso piu' preciso; inoltre si sono dedotti importanti considerazioni sulla correlazione tra processo di trasferimento dell'ossigeno e alcuni parametri di influenza (densita' diffusori, profondita' d'acqua, fouling diffusori, portata d'aria). La prova in liquame condotta presso l'impianto 'Andalo', ha rilevato un andamento crescente del fattore di correzione {alpha} verso 'in-out' di vasca.

  7. Evaluación de la calidad pedagógica de los MOOC

    Directory of Open Access Journals (Sweden)

    Rosabel Roig Vila

    2014-01-01

    Full Text Available Los MOOC han irrumpido de forma acelerada en el ámbito de la educación. Las principales universidades estadounidenses primero y, posteriormente, muchas otras –entre ellas, algunas españolas— están desarrollando a través de diversas plataformas en Internet, cursos bajo este formato. Al encontrarnos en una situación inicial de desarrollo de MOOC, son escasos los estudios sobre su evaluación. Por ello, el presente estudio ha realizado 129 evaluaciones a 52 MOOC ofertados por 10 plataformas. Se han analizado sus características pedagógicas a partir del Cuestionario de evaluación de la calidad de cursos virtuales (Arias, 2007. Del mismo modo se aborda la hipótesis de la existencia de diferencias estadísticamente significativas en cuanto a la calidad de los cursos en función de la plataforma que contiene los MOOC, analizando la influencia que el idioma o la presencia de una guía didáctica adecuada tiene sobre dicha calidad. Los resultados obtenidos en el presente trabajo no evidencian diferencias de forma generalizada entre los cursos, pero sí existen diferencias estadísticamente significativas en 5 de los 36 indicadores de calidad pedagógica propuestos.

  8. The Intercultural Education

    Directory of Open Access Journals (Sweden)

    María del Carmen Pérez Paredes

    2016-11-01

    Full Text Available Intercultural education is defined and conceived as a continuous process of development learning at all educational levels and integrators axes of Education, where the state with the participation of the family and society promote cultural diversity in the educational process citizen. That is why the aim of this study was to analyze aspects of intercultural education in order to foster the potential to ensure their integration into the proposals coming in curriculum design. It was based on the theory of complexity (Morin, 2008, 2001a, 2001b and the Theory of the Intercultural Education (Yampara, 2001. Methodologically was an analytical and documentary research which is inserted in studies of theoretical development. In that regard, it relied on authors such as Manual Pedagogical University Experimental Libertador (2003, Arias (2006: 27, Sánchez (2000. As a result it was found that aspects of complexity are present in the intercultural education in the form of principles such as the dialogic principle, the recursive principle, hologram tic principle, the principle of culture, the principle of autopoiesis, the principle of identity and the value of knowledge and wisdom, concluding that it can be said that intercultural education is present in the principles of complexity and are represented.

  9. Early interventional treatment with intranasal corticosteroids compared with postonset treatment in pollinosis.

    Science.gov (United States)

    Higaki, Takaya; Okano, Mitsuhiro; Makihara, Seiichiro; Fujiwara, Tazuko; Haruna, Takenori; Noda, Yohei; Kariya, Shin; Nishizaki, Kazunori

    2012-12-01

    The usefulness of early interventional treatment (EIT) with intranasal corticosteroids (INSs) compared with postonset treatment (POT) has not been clarified. To study the efficacy and safety of EIT with INSs compared with POT and placebo in Japanese cedar/cypress pollinosis. We designed a 3-armed, double-blinded, randomized, placebo-controlled trial. Patients received mometasone furoate nasal spray (EIT group: n = 25), placebo (n = 25), or 4 weeks of placebo followed by 8 weeks of mometasone (POT group: n = 25) for a 12-week period starting on February 1, 2011. The primary end point was the comparison of the total nasal symptom score (TNSS) among the 3 groups. Total ocular symptom score (TOSS), total naso-ocular symptom score (TSS), Allergic Rhinitis and Its Impact (ARIA) on Asthma classification, and safety were the main secondary end points. The placebo and POT groups, but not the EIT group, had a significant exacerbation of TNSS and TOSS soon after the start of pollen counts being high on consecutive days. The 12-week mean TSS in the EIT group (score, 2.3) was significantly lower than in the placebo (5.0; P INSs is superior to POT in controlling pollinosis. Copyright © 2012 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  10. The fossil record as a tool in cyclo stratigraphy: the incidence of Milankovitch-scale palaeoenvironmental changes on palaeocommunities

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez-Tovar, F. J.

    2013-06-01

    Cyclo stratigraphic analysis at the Milankovitch scale has to date mainly been approached through the sedimentary record, although palaeontological data (the fossil record) is known to provide useful evidence of orbital-scale cycles of precession, obliquity and eccentricity. Orbit ally induced marine and terrestrial palaeoenvironmental changes determine variable responses on the part of the resident communities. Aside from the disruption of communities, complex evolutionary responses including stasis, speciation and extinction phenomena may take place. Cyclic variations in the marine past-biota at the community level, or in some particular taxa, have often been associated with orbit ally induced changes in palaeoenvironmental parameters. Cyclo stratigraphic research into foraminifera, radiol aria and nanno fossil data, mainly from Cretaceous sediments, may contribute significantly to our understanding of the planktonic community's response, whereas the response of the benthic community, deriving mainly from benthic foraminifera and trace fossils, has been studied to a lesser extent. Recognition of Milankovitch cycles from terrestrial palaeocommunities is relatively scarce and based mainly on the study of Pliocene-Miocene pollen assemblages. Astronomical forced climate changes determine well known variations in the distribution of terrestrial vegetation, but can also affect the terrestrial animal community, including hominid populations (migration, dispersion and colonisation). (Author)

  11. Turbulent flow chromatography TFC-tandem mass spectrometry supporting in vitro/vivo studies of NCEs in high throughput fashion.

    Science.gov (United States)

    Verdirame, Maria; Veneziano, Maria; Alfieri, Anna; Di Marco, Annalise; Monteagudo, Edith; Bonelli, Fabio

    2010-03-11

    Turbulent Flow Chromatography (TFC) is a powerful approach for on-line extraction in bioanalytical studies. It improves sensitivity and reduces sample preparation time, two factors that are of primary importance in drug discovery. In this paper the application of the ARIA system to the analytical support of in vivo pharmacokinetics (PK) and in vitro drug metabolism studies is described, with an emphasis in high throughput optimization. For PK studies, a comparison between acetonitrile plasma protein precipitation (APPP) and TFC was carried out. Our optimized TFC methodology gave better S/N ratios and lower limit of quantification (LOQ) than conventional procedures. A robust and high throughput analytical method to support hepatocyte metabolic stability screening of new chemical entities was developed by hyphenation of TFC with mass spectrometry. An in-loop dilution injection procedure was implemented to overcome one of the main issues when using TFC, that is the early elution of hydrophilic compounds that renders low recoveries. A comparison between off-line solid phase extraction (SPE) and TFC was also carried out, and recovery, sensitivity (LOQ), matrix effect and robustness were evaluated. The use of two parallel columns in the configuration of the system provided a further increase of the throughput. Copyright 2009 Elsevier B.V. All rights reserved.

  12. The Boo of Viramontes’s Cafe: Retelling Ghost Stories, Central American Representing Social Death

    Directory of Open Access Journals (Sweden)

    Karina Oliva Alvarado

    2013-06-01

    Full Text Available Chicana author Helena María Viramontes’s culturally complex “The Cariboo Cafe,” renders a contemporaneous example of social death in the lives of undocumented migrants. Sociologist Orlando Patterson bases “social death” on the “profound natal alienation of the slave” (38 that once cut off from a past and future, promulgates the slave’s desocialization and depersonalization: systems also at play with undocumented Central American immigrants. While Patterson refers to an overt and systemized economic exploitation of a people, the concept remains relevant to this analysis, though symbolic. It examines a three-fold negation through the representational experiences of undocumented immigration, gender, and what Arturo Arias calls Central American “nonentity” (186, in Viramontes’s short story to address Central American differences erased by the utopian desire for reconciliation in Chicana/Latina texts. While social death is originally conceived and applied through “a mode of oppression through which slaves, and by extension those who grew up under the control of Jim Crow society” were coerced through hegemony (JanMohammed 246, its current relevance is allegorical to the conditions that delocalized and depersonalized literary representations of Central Americans. The question is what contemporary hegemonies socially kill the articulation of Central American subjectivities in a Latina/o US imaginary.

  13. Reviews of recent publications

    Directory of Open Access Journals (Sweden)

    2010-01-01

    Full Text Available Esperança Bielsa. The Latin American Urban Crónica: Between Literature and Mass Culture by Miguel González-Abellás Gene H. Bell-Villada, ed. Gabriel García Márquez’s One Hundred Years of Solitude: A Casebook by Miguel González-Abellás Albert Memmi. Decolonization and the Decolonized . Trans. Robert Bononno by Christa Jones Erin Graff Zivin. The Wandering Signifier: Rhetoric of Jewishness in the Latin American Imaginary by Naomi Lindstrom Dawn Fulton. Signs of Dissent: Maryse Condé and Postcolonial Crticism by Jane E. Evans Anne Lambright. Creating the Hybrid Intellectual: Subject, Space and the Feminine in the Narrative of José María Arguedas by Arturio Arias Andrew Sobanet. Jail Sentences: Representing Prison in Twentieth-Century French Fiction by Elisabeth-Christine Muelsch Olga López-Valero Colbert. The Gaze on the Past: Popular Culture and History in Antonio Muñoz Molina’s Novels by Jorge Pérez Warren Motte. Fiction Now: The French Novel in the Twenty-First Century by Martine Fernandes Hélène Cixous. Hyperdream . Trans. Beverley Bie Brahic. by Amy Baram Reid Jean-Michel Rabaté. 1913: The Cradle of Modernism by Safoi Babana-Hampton

  14. STUDIES IN ASTRONOMICAL TIME SERIES ANALYSIS. VI. BAYESIAN BLOCK REPRESENTATIONS

    International Nuclear Information System (INIS)

    Scargle, Jeffrey D.; Norris, Jay P.; Jackson, Brad; Chiang, James

    2013-01-01

    This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time suppressing the inevitable corrupting observational errors. We present a simple nonparametric modeling technique and an algorithm implementing it—an improved and generalized version of Bayesian Blocks—that finds the optimal segmentation of the data in the observation interval. The structure of the algorithm allows it to be used in either a real-time trigger mode, or a retrospective mode. Maximum likelihood or marginal posterior functions to measure model fitness are presented for events, binned counts, and measurements at arbitrary times with known error distributions. Problems addressed include those connected with data gaps, variable exposure, extension to piecewise linear and piecewise exponential representations, multivariate time series data, analysis of variance, data on the circle, other data modes, and dispersed data. Simulations provide evidence that the detection efficiency for weak signals is close to a theoretical asymptotic limit derived by Arias-Castro et al. In the spirit of Reproducible Research all of the code and data necessary to reproduce all of the figures in this paper are included as supplementary material.

  15. Aria de pixel: riprodutibilità aurática digitale Ar de pixel: reprodutibilidade aurática digital Pixel air: digital auratic reprodutibility

    Directory of Open Access Journals (Sweden)

    Mássimo Canevacci

    2010-04-01

    Full Text Available Il saggio parte dalla riflessione del testo Writing Culture di Clifford-Marcus. Dopo più di 20 anni, è possibile verificare come questa critica, anziché aprire verso il futuro, ha chiuso una fase della mono-scrittura etnografica basata sul concetto di retorica e autorità. Già nella metà degli anni '80 stavano nascendo forme compositive multi-linguistiche sperimentali che applicavano una "etnografia indisciplinata" a design, architettura, pubblicità, musica, cinema, web. Si apre la sfida per una università non solo basata su Facoltà territoriali. Diverse modalità di comunicare attraverso il digitale mescolano e sincretizzano le visioni dualistiche di Benjamin su aura e riproducibilità. La mia prospettiva finale è la riproducibilità auratica digitale.Este artigo parte da reflexão sobre o texto Culture de.i Clifford-Marcus. Após 20 anos de sua publicação, é possível verificar como a crítica feita por este autor fecou uma fase da mono-escritura etnográfica baseana no conceito de retórica e autoridade. Já na metade dos anos 80 estavam nascendo formas compositivas multi-linguísticas experimentais que aplicavam um "etnografia indisciplinada" ao design, arquitetura, publicidade, música, cinema, web, abrindo uma via para universidades não somente baseadas sobre faculdades territoriais. Diversas modalidades de comunicação são digitalmente mixadas, sincretizando o dualimsno de Benjamin sobre aura e repordutibilidade. A minha perspectiva final é a reprodutibilidade aurática digital.My essay starts from a reflection on Clifford-Marcus's Writing Culture. After more than 20 years, it is possible to verify that such a critique - instead of opening toward the future - was going to close to the traditional ethnographic writing based on rhetoric and authority. In the middle of the 80's, were spreading experimental compositive patterns, applying an "undisciplined ethnography" to design, architecture, advertising, music, cinema and web. The challenge toward a university based not only on territorial Faculty is open. Different forms of communication are digitally mixing and syncretizing the Benjamin visions on aura and reproducibility. My final perspective is the Digital Auratic Reproducibility.

  16. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis - A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement.

    Science.gov (United States)

    Hellings, P W; Fokkens, W J; Bachert, C; Akdis, C A; Bieber, T; Agache, I; Bernal-Sprekelsen, M; Canonica, G W; Gevaert, P; Joos, G; Lund, V; Muraro, A; Onerci, M; Zuberbier, T; Pugin, B; Seys, S F; Bousquet, J

    2017-09-01

    Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim of the current document was to propose a consensus on the position and gradual implementation of the principles of PM within existing adult treatment algorithms for allergic rhinitis (AR) and chronic rhinosinusitis (CRS). At the time of diagnosis, prediction of success of the initiated treatment and patient participation in the decision of the treatment plan can be implemented. The second-level approach ideally involves strategies to prevent progression of disease, in addition to prediction of success of therapy, and patient participation in the long-term therapeutic strategy. Endotype-driven treatment is part of a personalized approach and should be positioned at the tertiary level of care, given the efforts needed for its implementation and the high cost of molecular diagnosis and biological treatment. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  17. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis - A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

    DEFF Research Database (Denmark)

    Hellings, P W; Fokkens, W J; Bachert, C

    2017-01-01

    approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim...

  18. INFRACŢIUNILE PREVĂZUTE LA ART.238 ŞI 239 CP RM ÎN LUMINA AMENDAMENTELOR OPERATE ÎN CODUL PENAL LA 25.07.2014

    Directory of Open Access Journals (Sweden)

    Vitalie STATI

    2015-11-01

    Full Text Available Prezentul articol este consacrat analizei de drept penal a infracţiunilor prevăzute la art.238 şi 239 CP RM. Analiza este efectuată prin prisma Legii pentru modificarea şi completarea unor acte legislative din 25.07.2014. În acord cu aceasta, aria de aplicare a art.238 CP RM a fost extinsă asupra ipotezelor presupunând prezentarea cu bună ştiinţă a unor infor-maţii false în scopul obţinerii unui împrumut sau a unei despăgubiri/indemnizaţii de asigurare, ori al majorării sumei acestora, ori al obţinerii unui împrumut în condiţii avantajoase, dacă prin aceasta instituţiei financiare, organizaţiei financiare nebancare, asociaţiei de economii şi împrumut sau asigurătorului i-au fost cauzate daune. De asemenea, art.238 CP RM a fost completat cu alineatul (2: „Aceleaşi acţiuni care au cauzat daune în proporţii deosebit de mari”. Nu în ultimul rând, aria de aplicare a art.239 CP RM a fost extinsă asupra ipotezelor presupunând acordarea unui împru-mut sau a unei despăgubiri/indemnizaţii de asigurare cu încălcarea intenţionată a legii, a politicilor de acordare a împru-muturilor sau normelor de prudenţă financiară, dacă prin aceasta instituţiei financiare, organizaţiei financiare nebancare, asociaţiei de economii şi împrumut sau asigurătorului i-au fost cauzate daune.THE OFFENCES REFFERED TO AT ART.238 AND 239 PC RM IN THE LIGHT OF THE AMENDMENTS OPERATED TO THE PENAL CODE AT 07.25.2014This article is dedicated to the penal law analysis of the offences referred to at art.238 and 239 PC RM. The analysis is carried through the Law on amending and supplementing certain legislative acts from 25.07.2014. In line with these procedures, the application scope of art.238 PC RM was extended over the hypothesis assuming knowingly presenting false information in order to obtain a loan or reparation/insurance claim, or to increase their amount, or to obtain a loan on favorable terms, if all these were caused

  19. Factores de riesgo de bajo peso al nacer, estudio de tres años en el municipio Centro Habana: a 3-year study in Centro Habana municipality Risk factors of low birth weight

    Directory of Open Access Journals (Sweden)

    Rebeca Fajardo Luig

    2008-12-01

    Full Text Available Se realizó un estudio de casos y controles en el Hospital Ginecoobstétrico "América Arias", que abarcó el período 2004-2006, con el objetivo de identificar la asociación del bajo peso al nacer con algunos factores de riesgo conocidos de esta entidad. El grupo de estudio estuvo constituido por 108 mujeres residentes en Centro Habana, que parieron un recién nacido vivo bajo peso, y el grupo control por 216 mujeres, que tuvieron un neonato normopeso. De los recién nacidos bajo peso, un 65 % fueron pretérmino, un 39 % CIUR y un 4 % presentó la combinación de ambas entidades. Se demostró que existe relación entre el bajo peso al nacer y las edades maternas menor de 20 (14,8 % de los casos y mayor de 35 años (23,1 % de los casos, la baja talla materna (15,7 % de los casos, la baja escolaridad (17,5 % de los casos, el antecedente materno de hijo con bajo peso (13,8 % de los casos, el período intergenésico corto (69,4 % de los casos, el hábito de fumar (60,1 % de los casos, la desnutrición materna al inicio de la gestación (58,3 % de los casos y la ganancia materna insuficiente de peso durante el embarazo (54,6 % de los casos. El asma bronquial (13,8 %, la hipertensión arterial crónica (12,9 %, la preeclampsia (18,5 % y la anemia (18,5 % fueron las enfermedades más frecuentes encontradas en el grupo de estudio.A case-control study was conducted at "América Arias" Gynecoobstetric Hospital from 2004 to 2006 aimed at identifying the asociation of low birth weight with some risk factors known in this entity. The study group was composed of 108 females living in Centro Habana that gave birth a live low birth weight infant, and a control group that was made up of 216 females that had a normoweight infant. Of the low birth weight infants, 65 % were preterm, 39 % RIUG and 4 % presented a combination of both entities It was proved that there is a relationship between low birth weight and the maternal age under 20 (14.8 % of the cases and

  20. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

    NARCIS (Netherlands)

    Bousquet, J.; Khaltaev, N.; Cruz, A. A.; Denburg, J.; Fokkens, W. J.; Togias, A.; Zuberbier, T.; Baena-Cagnani, C. E.; Canonica, G. W.; van Weel, C.; Agache, I.; Aït-Khaled, N.; Bachert, C.; Blaiss, M. S.; Bonini, S.; Boulet, L.-P.; Bousquet, P.-J.; Camargos, P.; Carlsen, K.-H.; Chen, Y.; Custovic, A.; Dahl, R.; Demoly, P.; Douagui, H.; Durham, S. R.; van Wijk, R. Gerth; Kalayci, O.; Kaliner, M. A.; Kim, Y.-Y.; Kowalski, M. L.; Kuna, P.; Le, L. T. T.; Lemiere, C.; Li, J.; Lockey, R. F.; Mavale-Manuel, S.; Meltzer, E. O.; Mohammad, Y.; Mullol, J.; Naclerio, R.; O'Hehir, R. E.; Ohta, K.; Ouedraogo, S.; Palkonen, S.; Papadopoulos, N.; Passalacqua, G.; Pawankar, R.; Popov, T. A.; Rabe, K. F.; Rosado-Pinto, J.; Scadding, G. K.; Simons, F. E. R.; Toskala, E.; Valovirta, E.; van Cauwenberge, P.; Wang, D.-Y.; Wickman, M.; Yawn, B. P.; Yorgancioglu, A.; Yusuf, O. M.; Zar, H.; Annesi-Maesano, I.; Bateman, E. D.; Ben Kheder, A.; Boakye, D. A.; Bouchard, J.; Burney, P.; Busse, W. W.; Chan-Yeung, M.; Chavannes, N. H.; Chuchalin, A.; Dolen, W. K.; Emuzyte, R.; Grouse, L.; Humbert, M.; Jackson, C.; Johnston, S. L.; Keith, P. K.; Kemp, J. P.; Klossek, J.-M.; Larenas-Linnemann, D.; Lipworth, B.; Malo, J.-L.; Marshall, G. D.; Naspitz, C.; Nekam, K.; Niggemann, B.; Nizankowska-Mogilnicka, E.; Okamoto, Y.; Orru, M. P.; Potter, P.; Price, D.; Stoloff, S. W.; Vandenplas, O.; Viegi, G.; Williams, D.

    2008-01-01

    Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 million patients from all countries, all ethnic groups

  1. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

    Science.gov (United States)

    Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y Z; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman Rodriguez, M; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H A; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D Y; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L; Zhong, N; Zidarn, M; Mercier, J

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing.

  2. El mundo del libro: [enero a diciembre] de 1980

    Directory of Open Access Journals (Sweden)

    Agustín Rodríguez Garavito

    1980-06-01

    Full Text Available El documento presenta las siguientes reseñas de libros: -GUANO MALDITO-Por Joaquín Aguirre-Colección Andina-Bogotá-Ediciones Tercer Mundo-La Paz-Bogotá, Colombia. -El letrado español José María Alfaro y Polanco -FANTASMAS DE DOS MUNDOS-Por Arturo Uslar Pietri--Seix-Barral S. A. Barcelona- Caracas-México-Enero 1977-Avenida José Antonio-Madrid. -HOMENAJE A FERNANDO ANTONIO MARTÍNEZ-Estudios de Lingüística, filología, literatura e historia general-Publicaciones del Instituto Caro y Cuervo. LXVIII-Bogotá, 1979. -PROSAS-Por Jaime Barrera Parra- Empresa Colombiana de Petróleos - ECOPETROL - Editorial Andes, Bogotá. 1.347 páginas. -POESÍA-Por Rodolfo Moleiro -TENSO EN LA SOMBRA-Instituto de Cultura y Bellas Artes-Caracas, Venezuela. -REGRESO DEL VIENTO-Cuentos-Por Humberto Jaramillo Angel-Editorial Quin-Gráficas-Armenia, Colombia. -La poesía de Rafael Amaya -LA ÚLTIMA NOTICIA-Novela por Humberto Tafur Charry. -EL TRIUNFO DE LA MUERTE- Relatos-Por Gloria Nieto de Arias-Ediciones Tercer Mundo-Bogotá, Colombia. -COLOMBIA Y VENEZUELA-Integración-Por Manuel Roca Castellanos. -LOS ESPEJOS DEL TIEMPO-Por Eduardo Santa-Ediciones Príncipe-Bogotá, Colombia. -LOS OJOS DE LOS ENTERRADOS-Por Miguel Angel Asturias-Editorial Losada-Buenos Aires, Argentina. -APROXIMACIÓN A SIMÓN BOLÍVAR-Tema.

  3. Energy-Based Seismic Risk Evaluation of Tall Reinforced Concrete Building in Vancouver, BC, Canada, under Mw9 Megathrust Subduction Earthquakes and Aftershocks

    Directory of Open Access Journals (Sweden)

    Solomon Tesfamariam

    2017-05-01

    Full Text Available This article presents a seismic performance evaluation framework for reinforced concrete (RC buildings, comprising shear walls and gravity frames. The evaluation is undertaken within a performance-based earthquake engineering framework by considering regional seismicity and site-specific ground motion selection. Different engineering demand parameters (EDPs, i.e., maximum interstory drift ratio (MaxISDR and energy-based damage index, are considered as performance indicators. Various prediction models of EDPs are developed by considering four ground motion intensity measures (IMs, i.e., spectral acceleration at the fundamental period, Arias intensity, cumulative absolute velocity (CAV, and significant duration of ground motion. For this study, a 15-story RC building, located in Vancouver, BC, Canada, is considered as a case study. By using 50 mainshock and 50 mainshock–aftershock (MS-AS earthquake records (2 horizontal components per record and bidirectional loading, non-linear dynamic analyses are performed. Subsequently, the calculated MaxISDRs and damage indices are correlated with suitable IMs using cloud analysis, and the most efficient IM-EDP prediction models are selected by comparing standard deviations (SDs of the regression errors. The MaxISDR of the shear walls is less than 1% for the mainshock and MS-AS records. The energy-based damage index shows sensitivity to delineate impact of earthquake types and aftershocks. The CAV is showed to be the most efficient IM for the energy-based damage index.

  4. a historical overview from 1950 to the present

    Directory of Open Access Journals (Sweden)

    Karina Mendoza Quevedo

    2005-01-01

    Full Text Available Una de las primeras innovaciones en la evaluación objetiva en Cuba fue la traducción del MMPI del inglés al español. La traducción a la lengua española fue consecuencia de la relación personal entre el Doctor Starke Hathaway, uno de los autores del MMPI, e Idelfonso Bernal del Riesgo. El MMPI fue usado por numerosos clínicos en Cuba antes de 1959. Con el advenimiento de la revolución, la enseñanza y la práctica de la Psicología experimentaron drásticos cambios, surgiendo una «psicología cubana» para el desarrollo sociopolítico de la nación en un esfuerzo por independizarse de la influencia estadounidense y liberarse de lazos colonizadores. Los psicólogos cubanos continuaron sus trabajos clínicos y de investigación con el MMPI después de la revolución. Esta investigación es resumida en este estudio teórico. En los años noventa, el Doctor Guillermo Arias, de la Universidad de La Habana, contacta con el segundo autor de la Universidad de Minnesota para desarrollar y aplicar el MMPI- 2 en Cuba. Se describen todos estos acontecimientos.

  5. Demographic indicators of trust in federal, state and local government: implications for Australian health policy makers.

    Science.gov (United States)

    Meyer, Samantha B; Mamerow, Loreen; Taylor, Anne W; Henderson, Julie; Ward, Paul R; Coveney, John

    2013-02-01

    To provide baseline findings regarding Australians' trust in federal, state and local government. A computer-assisted telephone interviewing (CATI) survey was administrated during October to December 2009 to a random sample (n=1109) across Australia (response rate 41.2%). Binary logistic regression analyses were carried out by means of SPSS. Age, household size, household income, IRSD and ARIA were found to be significant indicators for trust in federal, state and local government. Trust in state government is lower for older respondents and respondents living in inner and outer regional areas. Trust in local council is lower in respondents living in inner regional areas, respondents living in disadvantaged areas, and respondents in the income bracket of $60001 to $100000. Trust in federal government is lower for older respondents and respondents living in disadvantaged areas. Of note is diminished trust in government among older, regional and lower income ($30001-$60000) respondents. Trust in all levels of government was found to be the lowest in population groups that are identified by empirical research and media to have the poorest access to government services. As a consequence, improved access to services for these populations may increase trust in health policy. Increased trust in health governance may in turn, ensure effective dissemination and implementation of health policies and that existing inequities are not perpetuated through distrust of health information and policy initiatives.

  6. [Modeling asthma evolution by a multi-state model].

    Science.gov (United States)

    Boudemaghe, T; Daurès, J P

    2000-06-01

    There are many scores for the evaluation of asthma. However, most do not take into account the evolutionary aspects of this illness. We propose a model for the clinical course of asthma by a homogeneous Markov model process based on data provided by the A.R.I.A. (Association de Recherche en Intelligence Artificielle dans le cadre de l'asthme et des maladies respiratoires). The criterion used is the activity of the illness during the month before consultation. The activity is divided into three levels: light (state 1), mild (state 2) and severe (state 3). The model allows the evaluation of the strength of transition between states. We found that strong intensities were implicated towards state 2 (lambda(12) and lambda(32)), less towards state 1 (lambda(21) and lambda(31)), and minimum towards state 3 (lambda(23)). This results in an equilibrium distribution essentially divided between state 1 and 2 (44.6% and 51.0% respectively) with a small proportion in state 3 (4.4%). In the future, the increasing amount of available data should permit the introduction of covariables, the distinction of subgroups and the implementation of clinical studies. The interest of this model falls within the domain of the quantification of the illness as well as the representation allowed thereof, while offering a formal framework for the clinical notion of time and evolution.

  7. New ways of insulin delivery.

    Science.gov (United States)

    Heinemann, L

    2010-02-01

    When Exubera (EXU), the first inhaled insulin formulation to make it through the clinical development process, was introduced to the market some years ago it was hoped that this would be the first in a series of novel insulin formulations applied by this route. In addition, it was hoped that inhaled insulin would pave the way for other alternative routes of insulin administration (ARIA), i.e. oral insulin, nasal insulin or transdermal insulin to mention only some of the different attempts that have been studied in the last 90 years. The failure of EXU, i.e. its withdrawal from the market due to insufficient market success, was followed by the cessation of nearly all other attempts to develop inhaled insulin formulations. Currently there is only one company (MannKind) which moves sturdily ahead with their Technosphere insulin. This company has submitted an NDA for their product recently and hopes to bring it to the market by the end of 2010 or early 2011. Even if the product is able to pass the approval hurdles in the USA and Europe, this does not guarantee that it will become a market success. Many diabetologists were sceptical about the need/advantages of inhaled insulin/EXU from the start and the introduction of this product has raised even more scepticism. Reports about 'side effects' (development of lung cancer in patients treated with EXU) of inhaled insulin are also not helpful, even if the causality of the appearance of cancer with this type of insulin therapy is not proven. One of the very negative consequences of stopping EXU are the huge financial losses to Pfizer. The managers in charge in other pharmaceutical companies and also most venture capitalists are reluctant to invest in ARIA nowadays. This in turn means that many of the small companies that try to develop new forms of insulin administration have issues when they try to find a big brother and/or sufficient financial support. Clearly the economic crisis has further aggravated this issue. One can

  8. Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project)

    DEFF Research Database (Denmark)

    Bousquet, J; Agache, I; Aliberti, M R

    2018-01-01

    The overarching goals of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) are to enable European citizens to lead healthy, active and independent lives whilst ageing. The EIP on AHA includes 74 Reference Sites. The aim of this study was to transfer innovation from an ...

  9. Air quality assessment in Varese area using Epiphytic Lichens; Valutazione della qualita` dell`aria nel Comune di Varese attraverso l`utilizzo di licheni epifiti

    Energy Technology Data Exchange (ETDEWEB)

    Zocchi, A.; Calamari, D. [Milan Univ. (Italy). III Fac. di Scienze; Roella, V. [USL, U.O. Fisica e Tutela Ambiente, Varese (Italy)

    1996-03-01

    The present work, within the municipality of Varese, has been carried out in 1993-1994 through a study on epiphytic lichens, as bioindicators of air pollution and bioaccumulators. The research method, used for the first part of this work, is based on the application of the Index of Atmospheric Purity, modified according to the Italian situation. The survey of the above mentioned area pointed out 6 strips, each having a different air quality level, shown on a map through different grids. The worst air quality was found in the town center and in some areas to the South and to the West, while the highest values of the I.A.P. were observed in the Northern part of the town. Moreover, the air pollution was evaluated by the Ecological Index of Wirth. Through the floristic analysis it was possible to check the influence of microclimate, of deposition of nitrogen substances and of light on the distribution of lichens. The achieved data confirmed what had already been reported in other scientific works; approaching to the town center pH values become lower and lower, because of a secondary acidification of the substrate, while an higher nitrofitism is observed in the agricultural zones. Analysis of heavy metals have been performed taking into account the ability of the lichens to accumulate these elements. The results have shown no correlation between the I.A.P. values and the metal concentrations, even if has been possible to point out a general increase in the metals arising from the combustion of red gasoline.

  10. Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project)

    NARCIS (Netherlands)

    Bousquet, J.; Agache, I.; Aliberti, M. R.; Angles, R.; Annesi-Maesano, I.; Anto, J. M.; Arnavielhe, S.; Asayag, E.; Bacci, E.; Bedbrook, A.; Bachert, C.; Baroni, I.; Barreto, B. A.; Bedolla-Barajas, M.; Bergmann, K. C.; Bertorello, L.; Bewick, M.; Bieber, T.; Birov, S.; Bindslev-Jensen, C.; Blua, A.; Bochenska Marciniak, M.; Bogus-Buczynska, I.; Bosnic-Anticevich, S.; Bosse, I.; Bourret, R.; Bucca, C.; Buonaiuto, R.; Burguete Cabanas, M. T.; Caillaud, D.; Caimmi, D. P.; Caiazza, D.; Camargos, P.; Canfora, G.; Cardona, V.; Carriazo, A. M.; Cartier, C.; Castellano, G.; Chavannes, N. H.; Cecci, L.; Ciaravolo, M. M.; Cingi, C.; Ciceran, A.; Colas, L.; Colgan, E.; Coll, J.; Conforti, D.; Correia de Sousa, J.; Cortés-Grimaldo, R. M.; Corti, F.; Costa, E.; Courbis, A. L.; Cousein, E.; Cruz, A. A.; Custovic, A.; Cvetkovski, B.; Dario, C.; da Silva, J.; Dauvilliers, Y.; de Blay, F.; Dedeu, T.; de Feo, G.; de Martino, B.; Demoly, P.; de Vries, G.; Di Capua Ercolano, S.; Di Carluccio, N.; Doulapsi, M.; Dray, G.; Dubakiene, R.; Eller, E.; Emuzyte, R.; Espinoza-Contreras, J. G.; Estrada-Cardona, A.; Farrell, J.; Farsi, A.; Ferrero, J.; Fokkens, W. J.; Fonseca, J.; Fontaine, J. F.; Forti, S.; Gálvez-Romero, J. L.; García-Cobas, C. I.; Garcia Cruz, M. H.; Gemicioğlu, B.; Gerth van Wijk, R.; Guidacci, M.; Gómez-Vera, J.; Guldemond, N. A.; Gutter, Z.; Haahtela, T.; Hajjam, J.; Hellings, P. W.; Hernández-Velázquez, L.; Illario, M.; Ivancevich, J. C.; Jares, E.; Joos, G.; Just, J.; Kalayci, O.; Kalyoncu, A. F.; Karjalainen, J.; Keil, T.; Khaltaev, N.; Klimek, L.; Kritikos, V.; Kull, I.; Kuna, P.; Kvedariene, V.; Kolek, V.; Krzych-Fałta, E.; Kupczyk, M.; Lacwik, P.; La Grutta, S.; Larenas-Linnemann, D.; Laune, D.; Lauri, D.; Lavrut, J.; Lessa, M.; Levato, G.; Lewis, L.; Lieten, I.; Lipiec, A.; Louis, R.; Luna-Pech, J. A.; Magnan, A.; Malva, J.; Maspero, J. F.; Matta-Campos, J. J.; Mayora, O.; Medina-Ávalos, M. A.; Melén, E.; Menditto, E.; Millot-Keurinck, J.; Moda, G.; Morais-Almeida, M.; Mösges, R.; Mota-Pinto, A.; Mullol, J.; Muraro, A.; Murray, R.; Noguès, M.; Nalin, M.; Napoli, L.; Neffen, H.; O'Hehir, R. E.; Onorato, G. L.; Palkonen, S.; Papadopoulos, N. G.; Passalacqua, G.; Pépin, J. L.; Pereira, A. M.; Persico, M.; Pfaar, O.; Pozzi, A. C.; Prokopakis, E.; Pugin, B.; Raciborski, F.; Rimmer, J.; Rizzo, J. A.; Robalo-Cordeiro, C.; Rodríguez-González, M.; Rolla, G.; Roller-Wirnsberger, R. E.; Romano, A.; Romano, M.; Romano, M. R.; Salimäki, J.; Samolinski, B.; Serpa, F. S.; Shamai, S.; Sierra, M.; Sova, M.; Sorlini, M.; Stellato, C.; Stelmach, R.; Strandberg, T.; Stroetmann, V.; Stukas, R.; Szylling, A.; Tan, R.; Tibaldi, V.; Todo-Bom, A.; Toppila-Salmi, S.; Tomazic, P.; Trama, U.; Triggiani, M.; Valero, A.; Valovirta, E.; Valiulis, A.; van Eerd, M.; Vasankari, T.; Vatrella, A.; Ventura, M. T.; Verissimo, M. T.; Viart, F.; Williams, S.; Wagenmann, M.; Wanscher, C.; Westman, M.; Wickman, M.; Young, I.; Yorgancioglu, A.; Zernotti, E.; Zuberbier, T.; Zurkuhlen, A.; de Oliviera, B.; Senn, A.

    2018-01-01

    The overarching goals of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) are to enable European citizens to lead healthy, active and independent lives whilst ageing. The EIP on AHA includes 74 Reference Sites. The aim of this study was to transfer innovation from an app

  11. Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project).

    Science.gov (United States)

    Bousquet, J; Agache, I; Aliberti, M R; Angles, R; Annesi-Maesano, I; Anto, J M; Arnavielhe, S; Asayag, E; Bacci, E; Bedbrook, A; Bachert, C; Baroni, I; Barreto, B A; Bedolla-Barajas, M; Bergmann, K C; Bertorello, L; Bewick, M; Bieber, T; Birov, S; Bindslev-Jensen, C; Blua, A; Bochenska Marciniak, M; Bogus-Buczynska, I; Bosnic-Anticevich, S; Bosse, I; Bourret, R; Bucca, C; Buonaiuto, R; Burguete Cabanas, M T; Caillaud, D; Caimmi, D P; Caiazza, D; Camargos, P; Canfora, G; Cardona, V; Carriazo, A M; Cartier, C; Castellano, G; Chavannes, N H; Cecci, L; Ciaravolo, M M; Cingi, C; Ciceran, A; Colas, L; Colgan, E; Coll, J; Conforti, D; Correia de Sousa, J; Cortés-Grimaldo, R M; Corti, F; Costa, E; Courbis, A L; Cousein, E; Cruz, A A; Custovic, A; Cvetkovski, B; Dario, C; da Silva, J; Dauvilliers, Y; De Blay, F; Dedeu, T; De Feo, G; De Martino, B; Demoly, P; De Vries, G; Di Capua Ercolano, S; Di Carluccio, N; Doulapsi, M; Dray, G; Dubakiene, R; Eller, E; Emuzyte, R; Espinoza-Contreras, J G; Estrada-Cardona, A; Farrell, J; Farsi, A; Ferrero, J; Fokkens, W J; Fonseca, J; Fontaine, J F; Forti, S; Gálvez-Romero, J L; García-Cobas, C I; Garcia Cruz, M H; Gemicioğlu, B; Gerth van Wijk, R; Guidacci, M; Gómez-Vera, J; Guldemond, N A; Gutter, Z; Haahtela, T; Hajjam, J; Hellings, P W; Hernández-Velázquez, L; Illario, M; Ivancevich, J C; Jares, E; Joos, G; Just, J; Kalayci, O; Kalyoncu, A F; Karjalainen, J; Keil, T; Khaltaev, N; Klimek, L; Kritikos, V; Kull, I; Kuna, P; Kvedariene, V; Kolek, V; Krzych-Fałta, E; Kupczyk, M; Lacwik, P; La Grutta, S; Larenas-Linnemann, D; Laune, D; Lauri, D; Lavrut, J; Lessa, M; Levato, G; Lewis, L; Lieten, I; Lipiec, A; Louis, R; Luna-Pech, J A; Magnan, A; Malva, J; Maspero, J F; Matta-Campos, J J; Mayora, O; Medina-Ávalos, M A; Melén, E; Menditto, E; Millot-Keurinck, J; Moda, G; Morais-Almeida, M; Mösges, R; Mota-Pinto, A; Mullol, J; Muraro, A; Murray, R; Noguès, M; Nalin, M; Napoli, L; Neffen, H; O'Hehir, R E; Onorato, G L; Palkonen, S; Papadopoulos, N G; Passalacqua, G; Pépin, J L; Pereira, A M; Persico, M; Pfaar, O; Pozzi, A C; Prokopakis, E; Pugin, B; Raciborski, F; Rimmer, J; Rizzo, J A; Robalo-Cordeiro, C; Rodríguez-González, M; Rolla, G; Roller-Wirnsberger, R E; Romano, A; Romano, M; Romano, M R; Salimäki, J; Samolinski, B; Serpa, F S; Shamai, S; Sierra, M; Sova, M; Sorlini, M; Stellato, C; Stelmach, R; Strandberg, T; Stroetmann, V; Stukas, R; Szylling, A; Tan, R; Tibaldi, V; Todo-Bom, A; Toppila-Salmi, S; Tomazic, P; Trama, U; Triggiani, M; Valero, A; Valovirta, E; Valiulis, A; van Eerd, M; Vasankari, T; Vatrella, A; Ventura, M T; Verissimo, M T; Viart, F; Williams, S; Wagenmann, M; Wanscher, C; Westman, M; Wickman, M; Young, I; Yorgancioglu, A; Zernotti, E; Zuberbier, T; Zurkuhlen, A; De Oliviera, B; Senn, A

    2018-01-01

    The overarching goals of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) are to enable European citizens to lead healthy, active and independent lives whilst ageing. The EIP on AHA includes 74 Reference Sites. The aim of this study was to transfer innovation from an app developed by the MACVIA-France EIP on AHA reference site (Allergy Diary) to other reference sites. The phenotypic characteristics of rhinitis and asthma multimorbidity in adults and the elderly will be compared using validated information and communication technology (ICT) tools (i.e. the Allergy Diary and CARAT: Control of Allergic Rhinitis and Asthma Test) in 22 Reference Sites or regions across Europe. This will improve the understanding, assessment of burden, diagnosis and management of rhinitis in the elderly by comparison with an adult population. Specific objectives will be: (i) to assess the percentage of adults and elderly who are able to use the Allergy Diary, (ii) to study the phenotypic characteristics and treatment over a 1-year period of rhinitis and asthma multimorbidity at baseline (cross-sectional study) and (iii) to follow-up using visual analogue scale (VAS). This part of the study may provide some insight into the differences between the elderly and adults in terms of response to treatment and practice. Finally (iv) work productivity will be examined in adults. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  12. IDENTIFICAREA DETERMINANŢILOR PSIHOSOCIALI AI EŞECULUI ŞCOLAR ŞI ASIGURAREA ADAPTĂRII ELEVILOR LA CERINŢELE ŞCOLII

    Directory of Open Access Journals (Sweden)

    Marta VICOL

    2016-12-01

    Full Text Available Dacă despre educaţie se vorbeşte că a cunoscut o evoluţie semnificativă, tot mai frecvent apar menţiuni despre eşec şcolar, insucces şcolar, ca o discrepanţă între exigenţele şcolare, posibilităţile şi, mai ales, rezultatele elevului, cu efecte negative în plan psihologic, în plan social, culminând în final cu o marginalizare socială. Insuccesul şcolar (eşecul şcolar exprimă, după cum s-a demonstrat, o discordanţă între cerinţele instructiv-educative şi posibilităţile fizice şi psihice ale elevului, el încetând să fie un fenomen aparent, aria şi formele sale de manifestare extinzându-se tot mai mult.IDENTIFYING THE PSYCHOSOCIAL DETERMINANTS OF SCHOOL FAILURE AND ENSURING STUDENTS ADAPT TO SCHOOL REQUIREMENTSIf education is mentioned as a significant development, more frequently occurring are mentions of school failure as a discrepancy between the demands of school, possibilities, and especially the results of the student, with negative effects psychologically, socially, culminating finally with social marginalization. The failure of school expresses, as was demonstrated, a discrepancy between the educational-instructive requirements and the physical and mental fitness abilities of the student, it ceasing to be an aparent phenomenon, its area and its forms of expression extending more and more.

  13. Dynamic interactions between musical, cardiovascular, and cerebral rhythms in humans.

    Science.gov (United States)

    Bernardi, Luciano; Porta, Cesare; Casucci, Gaia; Balsamo, Rossella; Bernardi, Nicolò F; Fogari, Roberto; Sleight, Peter

    2009-06-30

    Reactions to music are considered subjective, but previous studies suggested that cardiorespiratory variables increase with faster tempo independent of individual preference. We tested whether compositions characterized by variable emphasis could produce parallel instantaneous cardiovascular/respiratory responses and whether these changes mirrored music profiles. Twenty-four young healthy subjects, 12 musicians (choristers) and 12 nonmusician control subjects, listened (in random order) to music with vocal (Puccini's "Turandot") or orchestral (Beethoven's 9th Symphony adagio) progressive crescendos, more uniform emphasis (Bach cantata), 10-second period (ie, similar to Mayer waves) rhythmic phrases (Giuseppe Verdi's arias "Va pensiero" and "Libiam nei lieti calici"), or silence while heart rate, respiration, blood pressures, middle cerebral artery flow velocity, and skin vasomotion were recorded.Common responses were recognized by averaging instantaneous cardiorespiratory responses regressed against changes in music profiles and by coherence analysis during rhythmic phrases. Vocal and orchestral crescendos produced significant (P=0.05 or better) correlations between cardiovascular or respiratory signals and music profile, particularly skin vasoconstriction and blood pressures, proportional to crescendo, in contrast to uniform emphasis, which induced skin vasodilation and reduction in blood pressures. Correlations were significant both in individual and group-averaged signals. Phrases at 10-second periods by Verdi entrained the cardiovascular autonomic variables. No qualitative differences in recorded measurements were seen between musicians and nonmusicians. Music emphasis and rhythmic phrases are tracked consistently by physiological variables. Autonomic responses are synchronized with music, which might therefore convey emotions through autonomic arousal during crescendos or rhythmic phrases.

  14. THE R&D AND THE INTERNATIONALIZATION OF BUSINESS ORGANIZATIONS. THE CASE OF PHARMACEUTICAL COMPANIES

    Directory of Open Access Journals (Sweden)

    Alexandra-Maria GALAN

    2016-06-01

    Full Text Available Research and development represents one of the key activities of the business environment which shows company’s ability of continuous development. The interest in research and development can be observed in the global companies goals of being innovative by the goods and products offered. Combing these two elements helps improving company’s competitiveness which has a major contribution in the development of some strategic arias like health, energy or industry. The level of development of a company and the degree of diversification of the products and services offered is different from company to company, which highlights the fact that in the process of internationalization companies need to be focused to work on their advantages in order to keep the competition away. In these sort of cases companies decide to pay a particular attention in assigning resources for specific activities of research and development. The success of the pharmaceutical companies depends of the of research and development activity which objectives is to encourage creativity and innovation regarding the development of new medicines or other pharmaceutical products. The pharmaceutical industry would not be able to evolve without massive investments in research and development which is the base of the evolution of the company. On the other hand, the more they invest in research and development, the companies tend to expand their activity abroad in order to promote the comparative advantages obtained by the activity of research.

  15. Matrix approach to the simultaneous detection of multiple potato pathogens by real-time PCR.

    Science.gov (United States)

    Nikitin, M M; Statsyuk, N V; Frantsuzov, P A; Dzhavakhiya, V G; Golikov, A G

    2018-03-01

    Create a method for highly sensitive, selective, rapid and easy-to-use detection and identification of economically significant potato pathogens, including viruses, bacteria and oomycetes, be it single pathogen, or a range of various pathogens occurring simultaneously. Test-systems for real-time PCR, operating in the unified amplification regime, have been developed for Phytophthora infestans, Pectobacterium atrosepticum, Dickeya dianthicola, Dickeya solani, Ralstonia solanacearum, Pectobacterium carotovorum, Clavibacter michiganensis subsp. sepedonicus, potato viruses Y (ordinary and necrotic forms as well as indiscriminative test system, detecting all forms), A, X, S, M, potato leaf roll virus, potato mop top virus and potato spindle tuber viroid. The test-systems (including polymerase and revertase) were immobilized and lyophilized in miniature microreactors (1·2 μl) on silicon DNA/RNA microarrays (micromatrices) to be used with a mobile AriaDNA ® amplifier. Preloaded 30-reaction micromatrices having shelf life of 3 and 6 months (for RNA- and DNA-based pathogens, respectively) at room temperature with no special conditions were successfully tested on both reference and field samples in comparison with traditional ELISA and microbiological methods, showing perfect performance and sensitivity (1 pg). The accurate, rapid and user-friendly diagnostic system in a micromatrix format may significantly contribute to pathogen screening and phytopathological studies. © 2018 The Authors. Journal of Applied Microbiology published by John Wiley & Sons Ltd on behalf of The Society for Applied Microbiology.

  16. El Dios iranio Mithra y la Monarquía Persa Aqueménida

    Directory of Open Access Journals (Sweden)

    Israel Campo Méndez

    2013-11-01

    Full Text Available La figura del dios Mithra encarna en el mundo iranio antiguo la divinización de la idea de contrato. Desde el periodo de las tribus indo-arias que se asientan en la región desde mitad del Segundo Milenio a.c. el culto de esta divinidad evoluciona, vinculándose de manera especial con el poder político que ostentan los reyes y jefes tribales. El período de formación del Imperio Persa, bajo la dinastía aqueménida se convierte en un momento histórico importante, en el cual la presencia de Mithra logra mantenerse y seguir vinculada al poder real, a pesar de la implantación de la reforma zoroastriana, que en un principio desplaza su culto.The figure of the god Mithra embodies in the Ancient lranian World the deification of the contract idea. From the period of the Indo-Aryan tribes, settled in the region from half of the Second Millennium B.C., the cult of this divinity evolves, being linked in a special way with the political power that the kings and tribal bosses show. The period of formation of the Persian Empire, under the Aquemenid Dynasty becomes an important historical moment, in which the presence of Mithra is able  to stay and to continue linked to the royal power, in spite of the installation of the zoroastrian reformation that displaces its cult in a principle.

  17. Listenmee and Listenmee smartphone application: synchronizing walking to rhythmic auditory cues to improve gait in Parkinson's disease.

    Science.gov (United States)

    Lopez, William Omar Contreras; Higuera, Carlos Andres Escalante; Fonoff, Erich Talamoni; Souza, Carolina de Oliveira; Albicker, Ulrich; Martinez, Jairo Alberto Espinoza

    2014-10-01

    Evidence supports the use of rhythmic external auditory signals to improve gait in PD patients (Arias & Cudeiro, 2008; Kenyon & Thaut, 2000; McIntosh, Rice & Thaut, 1994; McIntosh et al., 1997; Morris, Iansek, & Matyas, 1994; Thaut, McIntosh, & Rice, 1997; Suteerawattananon, Morris, Etnyre, Jankovic, & Protas , 2004; Willems, Nieuwboer, Chavert, & Desloovere, 2006). However, few prototypes are available for daily use, and to our knowledge, none utilize a smartphone application allowing individualized sounds and cadence. Therefore, we analyzed the effects on gait of Listenmee®, an intelligent glasses system with a portable auditory device, and present its smartphone application, the Listenmee app®, offering over 100 different sounds and an adjustable metronome to individualize the cueing rate as well as its smartwatch with accelerometer to detect magnitude and direction of the proper acceleration, track calorie count, sleep patterns, steps count and daily distances. The present study included patients with idiopathic PD presented gait disturbances including freezing. Auditory rhythmic cues were delivered through Listenmee®. Performance was analyzed in a motion and gait analysis laboratory. The results revealed significant improvements in gait performance over three major dependent variables: walking speed in 38.1%, cadence in 28.1% and stride length in 44.5%. Our findings suggest that auditory cueing through Listenmee® may significantly enhance gait performance. Further studies are needed to elucidate the potential role and maximize the benefits of these portable devices. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. The contribution of woody plant materials on the several conditions in a space environment

    Science.gov (United States)

    Tomita-Yokotani, Kaori; Baba, Keiichi; Suzuki, Toshisada; Kimura, Shunta; Sato, Seigo; Katoh, Hiroshi; Abe, Yusuke; Katayama, Takeshi

    Woody plant materials have several utilization elements in our habitation environment on earth. The studies of woody plants under a space-environment in the vegetable kingdom have a high contribution to the study of various and exotic environmental responses, too. Woody plants can produce an excess oxygen, woody materials for the living cabin, and provide a biomass by cultivating crops and other species of creatures. Tree material would become to be a tool in closed bio-ecosystems such as an environment in a space. We named the trees used as material for the experiment related to space environments “CosmoBon”, small tree bonsai. Japanese cherry tree, “Sakura”, is famous and lovely tree in Japan. One species of “Sakura”, “Mamezakura, Prunus incisa”, is not only lovely tree species, but also suitable tree for the model tree of our purpose. The species of Prunus incisa is originally grown in volcano environment. That species of Sakura is originally grown on Mt. Fuji aria, oligotrophic place. We will try to build the best utilization usage of woody plant under the space environment by “Mamezakura” as a model tree. Here, we will show the importance of uniformity of materials when we will use the tree materials in a space environment. We will also discuss that tree has a high possibility of utilization under the space environments by using our several results related to this research.

  19. The design and implementation of the radiation therapy information management system (RTIMS) based on the workflow of radiation therapy

    International Nuclear Information System (INIS)

    Wu Qinhong; Li Gaofeng; Zhong Qiuzi; Hou Xiuyu; Li Ming; Xu Yonggang; He Jingxue

    2012-01-01

    Objective: To meet the special needs of the department of radiation oncology, a radiation therapy information management system (RTIMS) has been developed as a secondary database system to supplement the Varian Varis/Aria since 2007. Methods: The RTIMS server was used to run a database and web service of Apache + PHP + MySQL. The RTIMS sever's web service could be visited with Internet Explorer (IE) to input, search, count, and print information from about 30 workstations and 20 personal computers. As some workstations were installed with Windows and IE in English only, some functions had English version. Results: In past five years, as the RTIMS was implemented in the department, some further needs were met and more practical functions were developed. And now the RTIMS almost covered the whole workflow of radiation therapy (RT). By September 2011 , recorded patients data in the RTIMS is as follows: 3900 patients, 2600 outpatient RT records, 6800 progress notes, 1900 RT summaries, 6700 charge records, 83000 workload records, 3900 plan application forms, 1600 ICRT records. etc. Conclusions: The RTIMS based on the workflow of RT has been successfully developed and clinically implemented. And it was demonstrated to be user-friendly and was proven to significantly improve the efficiency of the department. Since it is an in-house developed system, more functions can be added or modified to further enhance its potentials in research and clinical practice. (authors)

  20. Tangshan 1976 earthquake: Modelling of the SH-wave motion in the area of Xiji-Langfu

    International Nuclear Information System (INIS)

    Sun, R.

    1995-06-01

    The reasons for the anomalous high macroseismic intensity caused in the Xiji-Langfu area by the Tangshan, 1976 earthquake can be found in its special geological conditions. This area is formed of deep deposits beside the Xiadian fault, that consist mainly of alluvium sands and clays, which are poorly consolidated with high water content. Resonances, excitation of local surface waves and their propagation cause strong amplifications and long durations of signals. Based on simulated strong ground motion, we have computed quantities commonly used for engineering purposes: the maximum amplitude (AMAX) and the total energy of ground motion (W), which is related to the Arias Intensity. AMAX and W do not decrease gradually as the epicentral distance increases, since the low velocities and the thickness of the deposits are responsible for the large increment of the values of AMAX and W inside the basin. On the two sides of the Xiadian fault AMAX and W can vary by 200% and 700% respectively. This computational result can be used to explain the large macroseismic intensity observed in the Xiji-Langfu area, in connection with the Tangshan earthquake. The spectral ratios show that over the whole area significant amplifications occur in the range of frequencies from 0.3 Hz to 1.5 Hz, while the largest amplification is above 6 and takes place around 3 Hz at a distance of about 112 km. from the epicentre. (author). 18 refs, 15 figs, 2 tabs

  1. Seismic evaluation of vulnerability for SAMA educational buildings in Tehran

    International Nuclear Information System (INIS)

    Amini, Omid Nassiri; Amiri, Javad Vaseghi

    2008-01-01

    Earthquake is a destructive phenomenon that trembles different parts of the earth yearly and causes many destructions. Iran is one of the (high seismicity) quack- prone parts of the world that has received a lot of pecuniary damages and life losses each year, schools are of the most important places to be protected during such crisis.There was no special surveillance on designing and building of school's building in Tehran till the late 70's, and as Tehran is on faults, instability of such buildings may cause irrecoverable pecuniary damages and especially life losses, therefore preventing this phenomenon is in an urgent need.For this purpose, some of the schools built during 67-78 mostly with Steel braced frame structures have been selected, first, by evaluating the selected Samples, gathering information and Visual Survey, the prepared questionnaires were filled out. With the use of ARIA and SABA (Venezuela) Methods, new modified combined method for qualified evaluations was found and used.Then, for quantified evaluation, with the use of computer 3D models and nonlinear statically analysis methods, a number of selected buildings of qualified evaluation, were reevaluated and finally with nonlinear dynamic analysis method the real behavior of structures on the earthquakes is studied.The results of qualified and quantified evaluations were compared and a proper Pattern for seismic evaluation of Educational buildings was presented. Otherwise the results can be a guidance for the person in charge of retrofitting or if necessary rebuilding the schools

  2. Relaciones sexuales en adolescentes colombianos y las implicaciones para la salud pública: una revisión de la prevalencia y algunas variables asociadas

    Directory of Open Access Journals (Sweden)

    Adalberto Campo-Arias

    2009-08-01

    Full Text Available ResumenEl deseo sexual se incrementa significativamente durante la adolescencia, en consecuencia, un número importante de hombres y mujeres adolescentes inician relaciones sexuales antes de la mayoría de edad. Se realizó una revisión de las publicaciones en Pubmed y Google académico que informaban la prevalencia de relaciones sexuales en adolescentes colombianos durante la década más reciente (1999-2008. Las palabras clave que se usaron fueron adolescentes (adolescents, estudiantes (students, comportamiento sexual (sexual behavior y Colombia. La prevalencia de relaciones sexuales estuvo entre 7.7% y 58%, media de 27.2%. Más años de edad, sexo masculino, mayor escolaridad y consumo de sustancias legales o ilegales se relacionaron con historia de relaciones sexuales. Los adolescentes informaron conductas sexuales de riesgo, con diferencias por género, como el uso inconsistente de condón, relaciones sexuales bajo el efecto de sustancias y relaciones sexuales con personas poco conocidas. Estos hallazgos tienen relevancia para salud pública sexual y reproductiva. Se deben diseñar programas integrales de intervención para promover un desarrollo sexual armónico y saludable en adolescentes colombianos. [Campo-Arias A. Relaciones sexuales en adolescentes colombianos y las implicaciones para la salud pública: una revisión de la prevalencia y algunas variables asociadas. MedUNAB 2009; 12:86-90].

  3. Comentario a la Presentación del Libro “Salud y Medio Ambiente, Un Compromiso de Todos” del Acad. Dr. José D. Cardona Arias.

    Directory of Open Access Journals (Sweden)

    Hernando Groot Liévano

    2005-09-01

    En repetidas ocasiones nos recuerda que el hombre orgullosamente considerado como el rey de la naturaleza, se ha convertido en el peor enemigo de la misma. Señala los efectos de esta acción devastadora con la tala exagerada de los bosques, el exceso de industrialización incontrolada, el crecimiento demográfico inmoderado a los cuales habría que añadir el egoísmo y la violencia que con tanta frecuencia exhibe nuestra especie humana...

  4. Low velocity floor level displacement ventilation systems: Technology assessment. Sistemi di distribuzione dell'aria a pavimento a bassa velocita': Vecchie e nuove conoscenze

    Energy Technology Data Exchange (ETDEWEB)

    Borjesson, J.A.; Bertomeu, L.; Marchetti, F.

    1992-12-01

    Although the concept of floor level air displacement ventilation is not in fact truly innovative given that it has already been tried during the 1980's, this paper shows that the combination of the advantageous natural cooling air circulation dynamics inherent in this method, combined with modern air diffusion equipment, offers interesting opportunities for energy conservation. The thermodynamics/air flow analysis indicates that from 20 to 40% energy savings can be obtained, in addition to reduced ventilation system operating times, with the effective application of low velocity floor level displacement air distribution systems as compared with conventional ventilation systems using the air mixing concept. It is shown how this innovative air cooling/recirculation technique is particularly suitable for conditions characterized by high air infiltration, high heating load and low indoor air pollution.

  5. Caracterización de neonatos con peso inferior a 2000 g Characterization of newborns with a birth weight under 2000 g

    Directory of Open Access Journals (Sweden)

    Odalys Martín Blanco

    2008-09-01

    Full Text Available INTRODUCCIÓN. Los niños con bajo peso al nacer son 20 veces más propensos a morir y presentan mayor morbilidad que los nacidos con buen peso. El objetivo de la presente investigación fue caracterizar a los recién nacidos con peso inferior a 2000 g, nacidos entre el 1ro. de enero del 2005 y el 31 de diciembre del 2006 en el Hospital Universitario "América Arias". MÉTODOS. Se realizó un estudio observacional, descriptivo-analítico, longitudinal y prospectivo, cuyo universo fueron los neonatos con peso inferior a 2000 g, nacidos en este período. En el análisis estadístico se utilizó la distribución de frecuencias, la media y la desviación estándar de la ganancia de peso, la talla, y las circunferencias cefálica y braquial. RESULTADOS. El 96,16 % de los pacientes estudiados nacieron con peso entre 1000 y 1999 g. El 93,27 % estuvo por debajo de las 36,6 semanas de gestación y en el 75,96 % de los casos el parto fue distócico. El 61,54 % de los neonatos tuvo peso adecuado para su edad gestacional. Predominaron los pacientes con factores de riesgo asociados. Más de la mitad presentó morbilidad asociada, principalmente por sepsis (25,96 %. Falleció el 10,58 % de los recién nacidos. CONCLUSIONES. Las principales causas del bajo peso de los recién nacidos fueron el embarazo múltiple y la enfermedad hipertensiva de la gestación. Las defunciones se comportaron por debajo de lo esperado. En los pacientes con crecimiento intrauterino retardado simétricos, la ganancia de peso y talla al alta fue significativamente mayor que en los asimétricos y adecuados para su edad gestacional.INTRODUCTION. Children with low birth weight are 20 times more prone to die and to have a greater morbidity than those with an adequate weight. The objective of this research was to characterize the newborn infants with a weight lower than 2000 g that were born between January 1st, 2005 and December 31st , 2006 in "America Arias" Children Hospital. METHODS

  6. Voz do cantor lírico e coordenação motora: uma intervenção baseada em Piret e Béziers Lyric singer voice and motor coordination: an intervention based on Piret and Béziers

    Directory of Open Access Journals (Sweden)

    Enio Lopes Mello

    2009-01-01

    Full Text Available OBJETIVO: Investigar os efeitos da aplicação de um Programa de Desenvolvimento da Coordenação Motora, baseado em Piret e Béziers, na voz do cantor lírico. MÉTODOS: Cinco cantores líricos profissionais executaram uma ária de ópera, de livre escolha, que foi filmada. Em seguida responderam a uma questão sobre a propriocepção ao cantar. Durante um mês submeteram-se ao Programa de Desenvolvimento da Coordenação Motora e ao final gravaram novamente a mesma ária e responderam a mesma questão. As filmagens foram enviadas para nove juizes profissionais (três fonoaudiólogos, três fisioterapeutas e três professores de canto que avaliaram a integração corpo e voz dos cantores por meio de análise perceptivo-auditiva e visual. Os cantores, após assistirem às duas filmagens, fizeram outra auto-avaliação. RESULTADOS: Na avaliação dos juízes: as duas sopranos, a mezzo-soprano e o baixo melhoraram a projeção da voz; o tenor melhorou a ressonância e o baixo melhorou também a respiração; com exceção do baixo todos ficaram com os gestos mais livres. Segundo relato dos cantores, os exercícios garantiram maior percepção da tensão muscular durante o canto e isso possibilitou melhor controle dos gestos. CONCLUSÃO: De acordo com a avaliação subjetiva os ajustes posturais, oriundos da execução dos exercícios da coordenação motora, provavelmente garantiram abertura da caixa torácica e melhoraram as condições da respiração dos cantores, durante o canto; este fato pode ter favorecido a verticalização da ressonância e a projeção da voz.PURPOSE: To investigate the effects of the application of a Motor Coordination Development Program, based on Piret and Béziers, on the voice of lyric singers. METHODS: Five professional lyric singers performed an opera aria of their choice, which was filmed. Next, they answered a question regarding their proprioception when singing. They were submitted to the Motor Coordination

  7. Sludge combustion in fluidized bed reactors at laboratory scale; Esperienze di combustione di fanghi in reattori a letto fluido in scala di laboratorio

    Energy Technology Data Exchange (ETDEWEB)

    Chirone, R.; Cammarota, A. [Consiglio Nazionale delle Ricerche, Istituto di Ricerche sulla Combustione, Naples (Italy)

    2001-03-01

    fanghi. Da un lato si e' caratterizzata l'entita' dei fenomeni di comminuzione delle particelle grossolane, dall'altro si sono condotte prove stazionarie di incenerimento in un reattore a letto fluido bollente da 40 mm di diametro. Il comportamento dei fanghi e' stato confrontato con quello di altri combustibili di interesse quali uno ricavato dai pneumatici (TDF), una biomassa dell'area mediterranea (Robinia Pseudoacacia) e un carbone bituminoso del Sud Africa. Le prove di combustione stazionaria sono state condotte alla temperatura di 850{sup 0}C, con una velocita' di fluidizzazione di 0.4 m/s e con differenti eccessi d'aria compresi fra il 14 e 98%. L'attivita' sperimentale ha indicato che con una opportuna scelta delle condizioni di esercizio il trattamento in letto fluidizzato di fanghi essiccati risulta un processo molto attraente. I fanghi hanno infatti mostrato una elevata efficienza di conversione del carbonio, maggiore del 98.9% per eccessi d'aria superiori al 20%, analoga a quella ottenuta in precedenti esperienze condotte in condizioni simili con un carbone Sudafricano (97-98%). Tali efficienze sono maggiori di quelle ottenute con un combustibile ricavato dai pneumatici (89-90%) e una biomassa, la Robinia Pseudoacacia (93-94%). Efficienze di combustione cosi' elevate possono essere interpretate considerando sia l'elevata reattivita' dei fanghi sia la bassa tendenza di questi a produrre particolato carbonioso durante la combustione.

  8. Infección neonatal: comportamiento en una unidad de cuidados intensivos Neonatal infection: behavior in an intensive care unit

    Directory of Open Access Journals (Sweden)

    Osmany Franco Argote

    2010-12-01

    Full Text Available INTRODUCCIÓN. El objetivo de este estudio fue caracterizar a los recién nacidos con sepsis atendidos en cuidados intensivos neonatales del Hospital «América Arias» en un período de 2 años. MÉTODOS. Se realizó una investigación cuantitativa, observacional, descriptiva y retrospectiva. El universo estuvo constituido por 214 neonatos. Las variables estudiadas fueron condiciones neonatales, manifestaciones clínicas de sepsis, gravedad, alteraciones humorales y antecedentes de procedimientos intervencionistas. Se hicieron combinaciones de algunas variables y se halló el valor de p para compararlas en neonatos con sepsis no grave o con sepsis grave. RESULTADOS. En el grupo estudiado la prematuridad, el bajo peso y el crecimiento intrauterino retardado alcanzaron cifras del 49,1 %, 42,1 % y 18,7 % respectivamente. El 72,9 % de los pacientes tuvo sepsis grave. Las manifestaciones clínicas más comunes fueron taquipnea (69,2 % y llenado capilar lento (57,9 %. La alteración humoral más frecuente fue la acidosis metabólica (63,6 % y el cateterismo umbilical fue el procedimiento intervencionista más frecuente (53,7 %. Predominaron las combinaciones de prematuridad y bajo peso (21,5 %, acidosis metabólica y neutrofilia (22 %, y asistencia respiratoria con cateterismo umbilical (21 % o epicutáneo (20,6 %. El valor de p fue de 0,001 entre pacientes con sepsis no grave y pacientes con sepsis grave en todas las combinaciones de intervencionismo, y no significativo en la combinación prematuro-bajo peso-crecimiento intrauterino retardado (CIUR. CONCLUSIONES. Hubo predominio de prematuridad, sepsis grave, taquipnea, cateterismo umbilical y acidosis metabólica. Las diferencias entre pacientes con sepsis no grave y con sepsis grave fueron significativas en todas las combinaciones de intervencionismo y de condición neonatal, pero no en la combinación prematuro-bajo peso-CIUR.INTRODUCTION. The aim of present study was to characterize the newborns

  9. Considerations for pattern placement error correction toward 5nm node

    Science.gov (United States)

    Yaegashi, Hidetami; Oyama, Kenichi; Hara, Arisa; Natori, Sakurako; Yamauchi, Shohei; Yamato, Masatoshi; Koike, Kyohei; Maslow, Mark John; Timoshkov, Vadim; Kiers, Ton; Di Lorenzo, Paolo; Fonseca, Carlos

    2017-03-01

    Multi-patterning has been adopted widely in high volume manufacturing as 193 immersion extension, and it becomes realistic solution of nano-order scaling. In fact, it must be key technology on single directional (1D) layout design [1] for logic devise and it becomes a major option for further scaling technique in SAQP. The requirement for patterning fidelity control is getting savior more and more, stochastic fluctuation as well as LER (Line edge roughness) has to be micro-scopic observation aria. In our previous work, such atomic order controllability was viable in complemented technique with etching and deposition [2]. Overlay issue form major potion in yield management, therefore, entire solution is needed keenly including alignment accuracy on scanner and detectability on overlay measurement instruments. As EPE (Edge placement error) was defined as the gap between design pattern and contouring of actual pattern edge, pattern registration in single process level must be considerable. The complementary patterning to fabricate 1D layout actually mitigates any process restrictions, however, multiple process step, symbolized as LELE with 193-i, is burden to yield management and affordability. Recent progress of EUV technology is remarkable, and it is major potential solution for such complicated technical issues. EUV has robust resolution limit and it must be definitely strong scaling driver for process simplification. On the other hand, its stochastic variation such like shot noise due to light source power must be resolved with any additional complemented technique. In this work, we examined the nano-order CD and profile control on EUV resist pattern and would introduce excellent accomplishments.

  10. iDC: A comprehensive toolkit for the analysis of residual dipolar couplings for macromolecular structure determination

    International Nuclear Information System (INIS)

    Wei Yufeng; Werner, Milton H.

    2006-01-01

    Measurement of residual dipolar couplings (RDCs) has become an important method for the determination and validation of protein or nucleic acid structures by NMRf spectroscopy. A number of toolkits have been devised for the handling of RDC data which run in the Linux/Unix operating environment and require specifically formatted input files. The outputs from these programs, while informative, require format modification prior to the incorporation of this data into commonly used personal computer programs for manuscript preparation. To bridge the gap between analysis and publication, an easy-to-use, comprehensive toolkit for RDC analysis has been created, iDC. iDC is written for the WaveMetrics Igor Pro mathematics program, a widely used graphing and data analysis software program that runs on both Windows PC and Mac OS X computers. Experimental RDC values can be loaded into iDC using simple data formats accessible to Igor's tabular data function. The program can perform most useful RDC analyses, including alignment tensor estimation from a histogram of RDC occurrence versus values and order tensor analysis by singular value decomposition (SVD). SVD analysis can be performed on an entire structure family at once, a feature missing in other applications of this kind. iDC can also import from and export to several different commonly used programs for the analysis of RDC data (DC, PALES, REDCAT) and can prepare formatted files for RDC-based refinement of macromolecular structures using XPLOR-NIH, CNS and ARIA. The graphical user interface provides an easy-to-use I/O for data, structures and formatted outputs

  11. Visual analogue scales (VAS): Measuring instruments for the documentation of symptoms and therapy monitoring in cases of allergic rhinitis in everyday health care: Position Paper of the German Society of Allergology (AeDA) and the German Society of Allergy and Clinical Immunology (DGAKI), ENT Section, in collaboration with the working group on Clinical Immunology, Allergology and Environmental Medicine of the German Society of Otorhinolaryngology, Head and Neck Surgery (DGHNOKHC).

    Science.gov (United States)

    Klimek, Ludger; Bergmann, Karl-Christian; Biedermann, Tilo; Bousquet, Jean; Hellings, Peter; Jung, Kirsten; Merk, Hans; Olze, Heidi; Schlenter, Wolfgang; Stock, Philippe; Ring, Johannes; Wagenmann, Martin; Wehrmann, Wolfgang; Mösges, Ralph; Pfaar, Oliver

    2017-01-01

    Visual analogue scales (VAS) are psychometric measuring instruments designed to document the characteristics of disease-related symptom severity in individual patients and use this to achieve a rapid (statistically measurable and reproducible) classification of symptom severity and disease control. VAS can also be used in routine patient history taking and to monitor the course of a chronic disease such as allergic rhinitis (AR). More specifically, the VAS has been used to assess effectiveness of AR therapy in real life, both in intermittent and persistent disease. This position paper takes a detailed look at the historical development of VAS and its method-specific principles. Particular focus is put on aspects of practical application in daily routine and on a critical discussion of the advantages and disadvantages of the individual methods. VAS are well validated for the measurement of AR symptoms and correlate well with the ARIA (allergic rhinitis and its impact on asthma) severity classification and also correlated well with rTNSS and RQLQ. Moreover, several treatment studies on AR have used VAS as an evaluation parameter. Thanks to the use of new (real-life and real-time) communication technologies, such as smartphone apps, Discussion: VAS can be used relatively simply and highly effectively to assess disease control. The VAS lends itself very well to digitization and has now been incorporated into a smartphone app (called Allergy Diary) to assess AR control and direct treatment decisions as part of an AR clinical decision support system (CDSS). MASK Rhinitis has developed this app, which is currently available in 15 different languages.

  12. Impacts of chemicals on waterfowl reproduction and survival

    Science.gov (United States)

    White, D.H.; Stickel, L.F.

    1975-01-01

    Residues of organochlorine pesticides, PCB's, heavy metals, and other toxic chemicals are ubiquitous in the biosphere and are commonly found in tissues and eggs of wild birds. This paper reviews research on the effects of these chemicals, with particular reference to waterfowl. Extensive mortality of waterfowl has occurred in the Gulf Coast region as a result of ingestion of aldrin-treated rice seed. Populations of fulvous tree ducks (Dendrocygna bicolor) have declined in recent years in that area. DDE impaired reproduction of both mallards (Anas platyrhynchos) and black ducks (Arias rubripes) in experimental studies, resulting in thin shells, cracked eggs, and poor hatching success. Eggs incubated by the hens broke and cracked more frequently than those in incubators. In the field, residues are higher in ducks that feed on animal material than in vegetarians; differences are pronounced both geographically and among species. Mercury at levels that occur in certain heavily polluted areas in the United States and Canada has, in experimental studies, lowered the reproductive success of mallards and black ducks and reduced the survival of ducklings. Oil spills have killed many waterfowl as a result of oiled feathers and the intake of oil and more indirect physiological effects have been shown experimentally. Pollutants may affect waterfowl indirectly by changing the habitat and directly as a result of intake of toxic substances. They are unlikely to have been directly limiting factors in populations of such species as mallards. Their involvement with problem of other species, including canvasbacks (Aythya valisineria) and mergansers has still to be explored.

  13. Il GEOatleta moderno

    Directory of Open Access Journals (Sweden)

    Francesco Bartoli

    2006-12-01

    Full Text Available Nell'ultimo decennio gli straordinari sforzi tecnologici hanno evoluto il settore geomatico e portato enormi vantaggi nell'ambito dei cosiddetti servizi a valore aggiunto. Tuttavia la svalutazione commerciale del sistema di navigazione satellitare ha fatto del navigatore un oggetto di uso comune, quasi alla pari del più quotato telefono cellulare. Scemata la corsa al cellulare più modaiolo è subentrata quella al navigatore satellitare più tecnologico con cartografia e punti di interesse più aggiornati. E' assai frequente trovare commercializzazioni degli operatori di telefonia che unisconoal dispositivo mobile il sistema di navigazione, grazie anche apolitiche di businness agreement tra le varie major. L'utilizzo dei dispositivi GPS è davvero ancora arenato alla semplice ricerca di un percorso o di un indirizzo da raggiungere? L'usodi tali apparecchiature può inserirsi all'interno di target quali l'intrattenimento e le attività ricreative? Negli ultimi anni stiamo riscoprendo la bellezza della natura e il piacere di dedicarci ad una serie di attività sportive outdoor che ci conciliano con essa, unendo ai benefici della mente quelli del corpo derivanti da una corretta sollecitazione della propria frequenza cardiaca. Questa mia relazione vuole essere un diario di viaggio nelle quotidiane attività all'aria aperta di un atleta non professionista, praticate durante le quattro stagioni sfruttando le tecnologie legate alla triangolazione satellitare.

  14. Modeling strong‐motion recordings of the 2010 Mw 8.8 Maule, Chile, earthquake with high stress‐drop subevents and background slip

    Science.gov (United States)

    Frankel, Arthur

    2017-01-01

    Strong‐motion recordings of the Mw 8.8 Maule earthquake were modeled using a compound rupture model consisting of (1) a background slip distribution with large correlation lengths, relatively low slip velocity, and long peak rise time of slip of about 10 s and (2) high stress‐drop subevents (asperities) on the deeper portion of the rupture with moment magnitudes 7.9–8.2, high slip velocity, and rise times of slip of about 2 s. In this model, the high‐frequency energy is not produced in the same location as the peak coseismic slip, but is generated in the deeper part of the rupture zone. Using synthetic seismograms generated for a plane‐layered velocity model, I find that the high stress‐drop subevents explain the observed Fourier spectral amplitude from about 0.1 to 1.0 Hz. Broadband synthetics (0–10 Hz) were calculated by combining deterministic synthetics derived from the background slip and asperities (≤1  Hz) with stochastic synthetics generated only at the asperities (≥1  Hz). The broadband synthetics produced response spectral accelerations with low bias compared to the data, for periods of 0.1–10 s. A subevent stress drop of 200–350 bars for the high‐frequency stochastic synthetics was found to bracket the observed spectral accelerations at frequencies greater than 1 Hz. For most of the stations, the synthetics had durations of the Arias intensity similar to the observed records.

  15. Benign endometrial proliferations mimicking malignancies: a review of problematic entities in small biopsy specimens.

    Science.gov (United States)

    Ip, Philip Pun-Ching

    2018-02-14

    Benign proliferations that mimic malignancies are commonly encountered during the course of assessment of small and fragmented endometrial samples. Although benign, endometrial epithelial metaplasias often coexist with premalignant or malignant lesions causing diagnostic confusion. The difficulty with mucinous metaplasia lies in its distinction from atypical mucinous glandular proliferations and mucinous carcinomas, which are associated with significant interobserver variability. Papillary proliferation of the endometrium is commonly associated with hormonal drugs and endometrial polyps and is characterised by papillae with fibrovascular cores covered by epithelial cells without cytologic atypia. They are classified into simple or complex papillary proliferations depending on the architectural complexity and extent of proliferation. Complex papillary proliferations are associated with a high risk of concurrent or subsequent hyperplasia with atypia/carcinoma. Papillary proliferations may have coexisting epithelial metaplasias and, most commonly, mucinous metaplasia and syncytial papillary change. Those with striking mucinous metaplasia overlap morphologically with papillary mucinous metaplasia. The latter has been proposed as a precursor of endometrial mucinous carcinoma. Misinterpreting the Arias-Stella reaction as a malignant or premalignant lesion is more likely to occur if the pathologist is unaware that the patient is pregnant or on hormonal drugs. Endometrial hyperplasia with secretory changes may occasionally be difficult to distinguish from the torturous and crowded glands of a late secretory endometrium. Endometrial polyps may have abnormal features that can be misinterpreted as endometrial hyperplasia or Mullerian adenosarcoma. Awareness of these benign endometrial proliferations and their common association with hormonal medication or altered endogenous hormonal levels will help prevent the over-diagnosis of premalignant and malignant lesions.

  16. Zerovalent bismuth nanoparticles inhibit Streptococcus mutans growth and formation of biofilm

    Directory of Open Access Journals (Sweden)

    Hernandez-Delgadillo R

    2012-04-01

    Full Text Available Rene Hernandez-Delgadillo1, Donaji Velasco-Arias2, David Diaz2, Katiushka Arevalo-Niño1, Marianela Garza-Enriquez1, Myriam A De la Garza-Ramos1, Claudio Cabral-Romero11Instituto de Biotecnologia, Centro de Investigacion y Desarrollo en Ciencias de la Salud, CIDICS, Facultad de Odontologia, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, Nuevo Leon, 2Facultad de Quimica, Universidad Nacional Autonoma de Mexico, Distrito Federal, MexicoBackground and methods: Despite continuous efforts, the increasing prevalence of resistance among pathogenic bacteria to common antibiotics has become one of the most significant concerns in modern medicine. Nanostructured materials are used in many fields, including biological sciences and medicine. While some bismuth derivatives has been used in medicine to treat vomiting, nausea, diarrhea, and stomach pain, the biocidal activity of zerovalent bismuth nanoparticles has not yet been studied. The objective of this investigation was to analyze the antimicrobial activity of bismuth nanoparticles against oral bacteria and their antibiofilm capabilities.Results: Our results showed that stable colloidal bismuth nanoparticles had 69% antimicrobial activity against Streptococcus mutans growth and achieved complete inhibition of biofilm formation. These results are similar to those obtained with chlorhexidine, the most commonly used oral antiseptic agent. The minimal inhibitory concentration of bismuth nanoparticles that interfered with S. mutans growth was 0.5 mM.Conclusion: These results suggest that zerovalent bismuth nanoparticles could be an interesting antimicrobial agent to be incorporated into an oral antiseptic preparation.Keywords: zerovalent bismuth nanoparticles, antimicrobial agent, biofilm, Streptococcus mutans

  17. Utilisation of general practitioner services by socio-economic disadvantage and geographic remoteness.

    Science.gov (United States)

    Turrell, Gavin; Oldenburg, Brian F; Harris, Elizabeth; Jolley, Damien

    2004-04-01

    To examine the association between socio-economic status (SES) and GP utilisation across Statistical Local Areas (SLAs) that differed in their geographic remoteness, and to assess whether Indigenous status and GP availability modified the association. Retrospective analysis of Medicare data for all unreferred GP consultations (1996/97) for 952 SLAs comprising the six Australian States. Geographic remoteness was ascertained using the Area Remoteness Index of Australia (ARIA), and SES was measured by grouping SLAs into tertiles based on their Index of Relative Socioeconomic Disadvantage score. Age/sex standardised rates of GP utilisation for each SLA. In SLAs classified as 'highly accessible', rates of GP use were 10.8% higher (95% CI 5.7-16.0) in the most socio-economically disadvantaged tertile after adjustment for Indigenous status and GP availability. A very different pattern of GP utilsation was found in 'remote/very remote' SLAs. After adjustment, rates of GP use in the most socio-economically disadvantaged tertile were 25.3% lower (95% CI 5.9-40.7) than in the most advantaged tertile. People in socio-economically disadvantaged metropolitan SLAs have higher rates of GP utilisation, as would be expected due to their poorer health. This is not true for people living in disadvantaged remote/very remote SLAs: in these areas, those most in need of GP services are least likely to receive them. Australia may lay claim to having a primary health care system that provides universal coverage, but we are still some way from having a system that is economically and geographically accessible to all.

  18. Integrating Remote Sensing Data, Hybrid-Cloud Computing, and Event Notifications for Advanced Rapid Imaging & Analysis (Invited)

    Science.gov (United States)

    Hua, H.; Owen, S. E.; Yun, S.; Lundgren, P.; Fielding, E. J.; Agram, P.; Manipon, G.; Stough, T. M.; Simons, M.; Rosen, P. A.; Wilson, B. D.; Poland, M. P.; Cervelli, P. F.; Cruz, J.

    2013-12-01

    Space-based geodetic measurement techniques such as Interferometric Synthetic Aperture Radar (InSAR) and Continuous Global Positioning System (CGPS) are now important elements in our toolset for monitoring earthquake-generating faults, volcanic eruptions, hurricane damage, landslides, reservoir subsidence, and other natural and man-made hazards. Geodetic imaging's unique ability to capture surface deformation with high spatial and temporal resolution has revolutionized both earthquake science and volcanology. Continuous monitoring of surface deformation and surface change before, during, and after natural hazards improves decision-making from better forecasts, increased situational awareness, and more informed recovery. However, analyses of InSAR and GPS data sets are currently handcrafted following events and are not generated rapidly and reliably enough for use in operational response to natural disasters. Additionally, the sheer data volumes needed to handle a continuous stream of InSAR data sets also presents a bottleneck. It has been estimated that continuous processing of InSAR coverage of California alone over 3-years would reach PB-scale data volumes. Our Advanced Rapid Imaging and Analysis for Monitoring Hazards (ARIA-MH) science data system enables both science and decision-making communities to monitor areas of interest with derived geodetic data products via seamless data preparation, processing, discovery, and access. We will present our findings on the use of hybrid-cloud computing to improve the timely processing and delivery of geodetic data products, integrating event notifications from USGS to improve the timely processing for response, as well as providing browse results for quick looks with other tools for integrative analysis.

  19. Multibeam collection for ARIA01WT: Multibeam data collected aboard Thomas Washington from 1982-01-12 to 1982-02-10, San Diego, CA to Papeete, French Polynesia

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  20. Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells

    International Nuclear Information System (INIS)

    Guo, Xianling; Zhang, Baihe; Wu, Mengchao; Wei, Lixin; Ma, Nannan; Wang, Jin; Song, Jianrui; Bu, Xinxin; Cheng, Yue; Sun, Kai; Xiong, Haiyan; Jiang, Guocheng

    2008-01-01

    Chemoresistance is one of the main obstacles to successful cancer therapy and is frequently associated with Multidrug resistance (MDR). Many different mechanisms have been suggested to explain the development of an MDR phenotype in cancer cells. One of the most studied mechanisms is the overexpression of P-glycoprotein (P-gp), which is a product of the MDR1 gene. Tumor cells often acquire the drug-resistance phenotype due to upregulation of the MDR1 gene. Overexpression of MDR1 gene has often been reported in primary gastric adenocarcinoma. This study investigated the role of p38-MAPK signal pathway in vincristine-resistant SGC7901/VCR cells. P-gp and MDR1 RNA were detected by Western blot analysis and RT-PCR amplification. Mitgen-activated protein kinases and function of P-gp were demonstrated by Western blot and FACS Aria cytometer analysis. Ap-1 activity and cell apoptosis were detected by Dual-Luciferase Reporter Assay and annexin V-PI dual staining. The vincristine-resistant SGC7901/VCR cells with increased expression of the multidrug-resistance 1 (MDR1) gene were resistant to P-gp-related drug and P-gp-unrelated drugs. Constitutive increases of phosphorylated p38-MAPK and AP-1 activities were also found in the drug-resistant cells. Inhibition of p38-MAPK by SB202190 reduced activator protein-1 (AP-1) activity and MDR1 expression levels and increased the sensitivity of SGC7901/VCR cells to chemotherapy. Activation of the p38-MAPK pathway might be responsible for the modulation of P-glycoprotein-mediated and P-glycoprotein-unmediated multidrug resistance in the SGC7901/VCR cell line

  1. Production of antiserum and development of radioimmunoassay for progesterone measurement in serum

    International Nuclear Information System (INIS)

    Abdalla, O.M; Abbas, S.H.

    2004-03-01

    The anti progesterone antibody was obtained by injection of local sudanese sheep (bevies arias) intramuscularly and subcutaneously using 11-a-hydroxy progesterone conjugated with bovine serum albumin and emulsified in friend's adjuvant. The blood samples collected one week after the 3 rd injection was tested for anti-progesterone antibodies. Different dilutions of antisera in Pbs containing 0.0.1 % BSA and 0.1 % Na N 3 (Ph 7.4) were made. Using these dilutions, polystyrene balls of 6.4 mm diameter were coated with a coating volume of 500 μ1/bead.The antibody dilution of 1/200000 was selected and used for assembling a kit to measure progesterone level in serum. Optimization of the assay condition resulted in the following recipes: Fifty μ1 of standard or Qc (Low, normal and high) from Bio Rad for 2 hours. The reaction medium aspirated, washed twice and read for 100 seconds in gamma counter. Assay validation tests including Linearity, recovery, reproducibility and comparability were done. In regards to linearity, the measured concentrations of progesterone in serum samples were plotted against the expected values. The correlation coefficient was 0.997 and a linear regression equation was Y=1.1019+0.9895 X. The mean recovery was 96.86% of the sample replicates ranged from 0.2% to 6%. between assay reproducibility was assessed fro the results obtained from 3 samples which were used for quality control in different assays. The results obtained were in the reference range and were close to each other. Comparison between local and American Dpc reagents for progesterone determination in serum showed high correlation high correlation where r 0.9492.(Author)

  2. Interdependence between damage indices and ground motion parameters based on Hilbert–Huang transform

    International Nuclear Information System (INIS)

    Alvanitopoulos, P F; Andreadis, I; Elenas, A

    2010-01-01

    Feature extraction from seismic accelerograms is a key issue in characterization of earthquake damage in structures. Until today, a number of effective classical parameters such as peak ground acceleration (PGA) and Arias intensity have been proposed for analyzing the earthquake motion records. The aim of this paper is to search for new crucial characteristic seismic parameters which provide information pertinent to the damage indicators of the structures. The first proposed parameter is the maximum amplitude (A HHT m ax ) and the second is the mean amplitude (A HHT m ean ). Emphasis of our work has been placed on the use of the Hilbert–Huang transform (HHT). A set of 13 natural accelerograms from worldwide well-known sites with strong seismic activity have been used. The HHT has been applied to the nonlinear and non-stationary data (earthquake recordings). Each complex seismic accelerogram is decomposed into several simple components called intrinsic mode functions (IMFs). Using the IMFs a three-dimensional time–frequency distribution of earthquake excitation is computed and two new seismic parameters are proposed and evaluated. After the numerical computation of all the seismic parameters (classical and proposed), nonlinear dynamic analysis is carried out to provide the post-seismic damage status of the structure under study. Two structural damage indices are utilized and the degree of interrelation among them and the seismic parameters is provided by correlation coefficients. Furthermore, two different reinforced concrete structures are examined. Results indicate the high correlation of the new seismic parameters (A HHT m ax , A HHT m ean ) with the damage indices and confirm that HHT is a promising tool for extracting information to characterize damage in structures

  3. Pilot study of mobile phone technology in allergic rhinitis in European countries: the MASK-rhinitis study.

    Science.gov (United States)

    Bousquet, J; Caimmi, D P; Bedbrook, A; Bewick, M; Hellings, P W; Devillier, P; Arnavielhe, S; Bachert, C; Bergmann, K C; Canonica, G W; Chavannes, N H; Cruz, A A; Dahl, R; Demoly, P; De Vries, G; Mathieu-Dupas, E; Finkwagner, A; Fonseca, J; Guldemond, N; Haahtela, T; Hellqvist-Dahl, B; Just, J; Keil, T; Klimek, L; Kowalski, M L; Kuitunen, M; Kuna, P; Kvedariene, V; Laune, D; Pereira, A M; Carreiro-Martins, P; Melén, E; Morais-Almeida, M; Mullol, J; Muraro, A; Murray, R; Nogueira-Silva, L; Papadopoulos, N G; Passalacqua, G; Portejoie, F; Price, D; Ryan, D; Samolinski, B; Sheikh, A; Siroux, V; Spranger, O; Todo Bom, A; Tomazic, P V; Valero, A; Valovirta, E; Valiulis, A; VandenPlas, O; van der Meulen, S; van Eerd, M; Wickman, M; Zuberbier, T

    2017-06-01

    The use of Apps running on smartphones and tablets profoundly affects medicine. The MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) App (Allergy Diary) assesses allergic rhinitis symptoms, disease control and impact on patients' lives. It is freely available in 20 countries (iOS and Android platforms). To assess in a pilot study whether (i) Allergy Diary users were able to properly provide baseline characteristics (ii) simple phenotypic characteristics based upon data captured by the Allergy Diary could be identified and (iii) information gathered by this study could suggest novel research questions. The Allergy Diary users were classified into six groups according to the baseline data that they entered into the App: (i) asymptomatic; (ii) nasal symptoms excluding rhinorrhea; (iii) rhinorrhea; (iv) rhinorrhea plus 1-2 nasal/ocular symptoms; (v) rhinorrhea plus ≥3 nasal/ocular symptoms; and (vi) rhinorrhea plus all nasal/ocular symptoms. By 1 June 2016, 3260 users had registered with the Allergy Diary and 2710 had completed the baseline questionnaire. Troublesome symptoms were found mainly in the users with the most symptoms. Around 50% of users with troublesome rhinitis and/or ocular symptoms suffered work impairment. Sleep was impaired by troublesome symptoms and nasal obstruction. This is the first App (iOS and Android) to have tested for allergic rhinitis and conjunctivitis. A simple questionnaire administered by cell phones enables the identification of phenotypic differences between a priori defined rhinitis groups. The results suggest novel concepts and research questions in allergic rhinitis that may not be identified using classical methods. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. 11 Efficacy and Tolerability of HDM Injective Immunotherapy With Monomeric Allergoid

    Science.gov (United States)

    Compalati, Enrico; Atzeni, Isabella; Cabras, Sergio; Fancello, Paolo; Gaspardini, Giulio; Longo, Rocco; Patella, Vincenzo; Tore, Giorgio

    2012-01-01

    Background Subcutaneous immunotherapy (SCIT) is an effective treatment of respiratory allergy and carbamylated monomeric allergoids (monoids), by virtue of their reduced IgE-binding activity, resulted clinically safe by sublingual administration. Purpose of this study was to investigate the efficacy and tolerability of immunotherapy with house dust mites (HDM) monoid administered by injective route in patients with allergic rhinoconjunctivitis (AR). Methods A preparation of 0.70 mL of 10 BU/mL containing modified extract with 50% Dermatophagoides pteronyssinus and 50% Dermatophagoides farinae (amount of major allergen: 4 μg of group 1 per milliliter) was delivered monthly for 12 months, following a 5-week build-up induction phase (0.10–0.20–0.30–0.50–0.70 mL), to 58 patients (60% males, mean age 25.1 ± 12.7) suffering from AR due to mites for at least 2 years, whereas 60 patients with similar baseline characteristics were observed as controls. All patients were allowed to assume traditional drug therapy for their condition. At the end of the study changes from baseline in symptoms scores, in number of days with drug assumption, in severity of AR (according to ARIA classification) were compared between the 2 groups; moreover an overall assessment of clinical efficacy and tolerability was based on patients' and physicians' judgements (unsatisfactory, mild, good, optimal). Results In respect to baseline both groups showed, after 1 year, an improvement in symptoms score (P allergoid was associated with a significant clinical benefit observed through objective and subjective outcomes; the traditional safety of monomeric allergoids was confirmed by the subjective judgements of tolerability.

  5. Epidemiological and molecular surveillance of influenza and respiratory syncytial viruses in children with acute respiratory infections (2004/2005 season

    Directory of Open Access Journals (Sweden)

    Alessandra Zappa

    2008-03-01

    Full Text Available Objective. During the 2004/2005 influenza season an active virological surveillance of influenza viruses and respiratory syncytial virus (RSV was carried out to monitor the epidemiologic trend of acute respiratory infections (ARI in the paediatric community. Materials and methods. 100 patients (51 males, 49 females; mean age: 19 months, either treated at the Emergency Unit or hospitalized in the Pediatric Unit of “San Carlo Borromeo Hospital” (Milan, reporting symptoms related to ARI were enrolled. Pharyngeal swabs were collected for virological investigation by: 1 multiplexnested- PCR for the simultaneous identification of both influenza A and B viruses and RSV; 2 multiplex-nested- PCR for the subtyping of influenza A viruses (H1 and H3. Results. 12% (12/100 subjects were infected with influenza A virus, 4% (4/100 with influenza B virus and 14 (14% with RSV. Of all the 12 influenza A positive samples 4 (33.3% belonged to subtype H1 and 8 (66.7% to subtype H3. Bronchiolitis and bronchitis episodes were significantly higher among RSV-infected subjects than among influenza- infected subjects (42.8% vs 6.2%; p<0.05 and 35.7% vs 6.2%; p<0.05, respectively. Pneumonia episodes occurred similarly both in influenza-infected children and in RSV-infected ones. Conclusions. During the 2004/2005 influenza season, influenza viruses and RSV were liable for high morbidity among paediatric subjects.The present study underlies the importance of planning an active surveillance of respiratory viral infections among paediatric cases requiring hospitalization due to ARI.A thorough analysis of target population features, of viruses antigenic properties and seasonality will be decisive in the evaluation of each clinical event.

  6. European Symposium on Precision Medicine in Allergy and Airways Diseases: Report of the European Union Parliament Symposium (October 14, 2015).

    Science.gov (United States)

    Muraro, A; Fokkens, W J; Pietikainen, S; Borrelli, D; Agache, I; Bousquet, J; Costigliola, V; Joos, G; Lund, V J; Poulsen, L K; Price, D; Rolland, C; Zuberbier, T; Hellings, P W

    2016-05-01

    The European Academy of Allergy and Clinical Immunology (EAACI), the European Rhinologic Society (ERS), and the European Medical Association (EMA) organized, on October 14, 2015, a symposium in the European Parliament in Brussels on Precision Medicine in Allergy and Airways Diseases, hosted by MEP David Borrelli, and with active participation of the EU Commissioner for Health and Food Safety Vytenis Andriukaitis, MEP Sirpa Pietikainen, Chair of the European Parliament Interest Group on Allergy and Asthma, the European Respiratory Society (ERS), the European Federations of Allergy and Airways Diseases Patients Associations (EFA), the Global Allergy and Asthma European Network (Ga2len), Allergic Rhinitis and Its Impact on Asthma (ARIA), and the Respiratory Effectiveness Group (REG). The socioeconomic impact of allergies and chronic airways diseases cannot be underestimated, as they represent the most frequently diagnosed chronic noncommunicable diseases in the EU; 30% of the total European population is suffering from allergies and asthma, and more than half are deprived from adequate diagnosis and treatment. Precision medicine represents a novel approach, embracing four key features: personalized care based on molecular, immunologic, and functional endotyping of the disease, with participation of the patient in the decision-making process of therapeutic actions, and considering predictive and preventive aspects of the treatment. Implementation of precision medicine into clinical practice may help to achieve the arrest of the epidemic of allergies and chronic airways diseases. Participants underscored the need for optimal patient care in Europe, supporting joint action plans for disease prevention, patient empowerment, and cost-effective treatment strategies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Il portale del Servizio Geologico d’Italia

    Directory of Open Access Journals (Sweden)

    Loredana Battaglini

    2006-12-01

    Full Text Available Nell'ultimo decennio gli straordinari sforzi tecnologici hanno evoluto il settore geomatico e portato enormi vantaggi nell'ambito dei cosiddetti servizi a valore aggiunto. Tuttavia la svalutazione commerciale del sistema di navigazione satellitare ha fatto del navigatore un oggetto di uso comune, quasi alla pari del più quotato telefono cellulare. Scemata la corsa al cellulare più modaiolo è subentrata quella al navigatore satellitare più tecnologico con cartografia e punti di interesse più aggiornati. E' assai frequente trovare commercializzazioni degli operatori di telefonia che unisconoal dispositivo mobile il sistema di navigazione, grazie anche apolitiche di businness agreement tra le varie major. L'utilizzo dei dispositivi GPS è davvero ancora arenato alla semplice ricerca di un percorso o di un indirizzo da raggiungere? L'uso di tali apparecchiature può inserirsi all'interno di target quali l'intrattenimento e le attività ricreative? Negli ultimi anni stiamo riscoprendo la bellezza della natura e il piacere di dedicarci ad una serie di attività sportive outdoor che ci conciliano con essa, unendo ai benefici della mente quelli del corpo derivanti da una corretta sollecitazione della propria frequenza cardiaca. Questa mia relazione vuole essere un diario di viaggio nelle quotidiane attività all'aria aperta di un atleta non professionista, praticate durante le quattro stagioni sfruttando le tecnologie legate alla triangolazione satellitare.

  8. Atmospheric lidar: legislative, scientific and technological aspects; Lidar atmosferico. Aspetti legislativi, scientifici e tecnologici

    Energy Technology Data Exchange (ETDEWEB)

    Barbini, R.; Colao, F.; Fiorani, L.; Palucci, A. [ENEA, Divisione Fisica Applicata, Centro Ricerche Frascati, Frascati, RM (Italy)

    2000-07-01

    The Atmospheric Lidar is one of the systems of the Mobile Laboratory of Laser Remote Sensing under development at the ENEA Research Center of Frascati. This technical report addresses the legislative, scientific and technological aspects that are the basis for the identification of the requirements, the definition of the architecture and the fixation of the specifications of the Atmospheric Lidar. The problems of air pollution are introduced in section 2. A summary of the Italian laws on that topic is then given. Section 4 provides a survey of the atmospheric measurements that can be achieved with the lidar. The sensitivity in the monitoring of pollutants is discussed in section 5. The other systems of the Mobile Laboratory of Laser Remote Sensing are shortly described in section 6. The last section is devoted to conclusions and perspectives. [Italian] Il lidar atmosferico e' uno dei sistemi del Laboratorio Mobile di Telerilevamento Laser in corso di realizzazione presso il Centro Ricerche di Frascati dell'ENEA. Questo rapporto tecnico discute gli aspetti legislativi, scientifici, tecnologici che sono alla base dell'individuazione dei requisiti, della definizione dell'architettura e della fissazione delle specifiche del Lidar atmosferico. La problematica dell'inquinamento dell'aria e' introdotta nella sezione 2. Segue un riassunto della legislazione italiana su tale tematica. La sezione 4 offre una panoramica delle misure atmosferiche realizzabili con il Lidar. La sensibilita' nel monitoraggio di inquinanti e' discussa nella sezione 5. Gli altri sistemi del Laboratorio Mobile di Telerilevamento Laser sono descritti brevemente nella sezione 6. L'ultima sezione e' dedicata alle conclusioni e alle prospettive.

  9. Standardized models for atmospheric diffusion applied to an highly industrialized area (Taranto, Italy): results, comparisons and future trends; Applicazione di modelli standardizzati di diffusione atmosferica all`area ad elevata concentrazione industriale di Taranto: confronti e linee di sviluppo

    Energy Technology Data Exchange (ETDEWEB)

    Brofferio, C.; Racalbuto, S. [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dip. Ambiente; Desiato, F. [ANPA, Rome (Italy); Del Buono, P.

    1998-12-31

    In this paper the authors present and discuss the results obtained running the DIMULA code (DIffusion MULtisources in Atmosphere), the model has been applied to the industrial area of Taranto (Puglia, Italy), characterized by a large number of air emission sources of SO{sub 2} NOx, PST. Due to the lack of controlled data on emission and air concentrations outputs, the DIMULA code outputs were compared with those obtained from others dispersion models such as CDM (Climatological Dispersion Model) by EPA and AMETISTA (Air Quality based on MEteorological TIme Series and Turbolence Analysis) by ANPA. The air concentration values estimated by the three models are similar comparing the order of magnitude; only under specific meteo conditions (such as wind calm conditions) and near the emission sources, the three models lead to different results. [Italiano] Nel presente lavoro sono presentati e discussi i risultati ottenuti applicando il codice DIMULA (DIffusione MULtisorgente Atmosferica) dell`ENEA all`area industriale di Taranto (Puglia), caratterizzata da un elevato numero di sorgenti emissive in aria di SO{sub 2} NOx, PST. In mancanza di dati controllati di emissione e di concentrazione che fornissero indicazioni sulla validita` dei valori ottenuti, le valutazioni del DIMULA sono state confrontate con quelle fornite da altri modelli quali il CDM (Climatological Dispersion Model) dell`EPA e l`AMETISTA (Air Quality based on MEteorological TIme Series and Turbolence Analysis) dell`ANPA. Lo studio ha mostrato che le stime dei valori di concentrazione ottenute con i tre modelli sono in generale simili in ordine di grandezza tranne che in prossimita` delle sorgenti e in particolari condizioni meteorologiche quali la calma di vento.

  10. The ENEA calibration service for ionising radiations. Part 1: Photons; Il centro di taratura per la radiazioni ionizzanti di Bologna. Parte 1: Fotoni

    Energy Technology Data Exchange (ETDEWEB)

    Monteventi, F.; Sermenghi, I. [ENEA Centro Ricerche Ezio Clementel, Bologna (Italy). Dipt. Ambiente

    1999-07-01

    The ENEA (National Agency for New Technology, Energy and the Environment) calibration service for ionizing radiations has been active for 40 years in the secondary standard dosimetry laboratory web. It has been the first center, in 1985, to be acknowledges by the Italian calibration service (SIT) for the two quantities for photons: exposure and air kerma. Since the Institute for the Radiation Protection of ENEA has moved to the new site in Montecuccolino (Bologna, Italy) in 1995, the whole laboratory has been renovated and all irradiation rooms together with radiation source and equipment have been reorganized according to the {chi}, {gamma}, {beta} and neutron fields metrology requirements. The aim of this report, as the first part of a report describing all facilities available at the service, is to give a detailed description of all equipment s qualified for photon fields metrology including the secondary standards and the calibration procedures performed for radiation monitoring devices and dosemeters. [Italian] Il centro di taratura dell'ENEA di Bologna opera nel campo della metrologia secpndaria da quasi 40 anni ed e' stato il primo centro nel 1985 ad essere riconosciuto dal SIT (Servizio di Taratura in Italia) per le grandezze esposizione e Kerma in aria. Con l'insediamento di tutto l'Istituto per la Radioprotezione nella nuova sede di Montecuccolino sono state ricostruite e riorganizzate anche tutte le sale di irraggiamento e tutti gli impianti radiogeni a disposizione per la metrologia delle radiazioni X, gamma, beta e neutroni. Intenzione di questo primo rapporto e' descrivere le attrezzature qualificate per la metrologia fotonica, dei campioni di misura e delle procedure adottate per la taratura degli strumenti e dei dosimetri.

  11. Mobile Phones and Social Media Empower the Citizen Seismologist

    Science.gov (United States)

    Bray, J.; Dashti, S.; Reilly, J.; Bayen, A. M.; Glaser, S. D.

    2014-12-01

    Emergency responders must "see" the effects of an earthquake clearly and rapidly for effective response. Mobile phone and information technology can be used to measure ground motion intensity parameters and relay that information to emergency responders. However, the phone sensor is an imperfect device and has a limited operational range. Thus, shake table tests were performed to evaluate their reliability as seismic monitoring instruments. Representative handheld devices, either rigidly connected to the table or free to move, measured shaking intensity parameters well. Bias in 5%-damped spectral accelerations measured by phones was less than 0.05 and 0.2 [log(g)] during one-dimensional (1-D) and three-dimensional (3-D) shaking in frequencies ranging from 1 Hz to 10 Hz. They did tend to over-estimate the Arias Intensity, but this error declined for stronger motions with larger signal-to-noise ratios. Additionally, much of the data about infrastructure performance and geotechnical effects of an earthquake are lost soon after an earthquake occurs as efforts move to the recovery phase. A better methodology for reliable and rapid collection of perishable hazards data will enhance scientific inquiry and accelerate the building of disaster-resilient cities. Post-earthquake reconnaissance efforts can be aided through the strategic collection and reuse of social media data and other remote sources of information. This is demonstrated through their use following the NSF-sponsored GEER response to the September 2013 flooding in Colorado. With these ubiquitous measurement devices in the hands of the citizen seismologist, a more accurate and rapid portrayal of the damage distribution during an earthquake may be provided to emergency responders and to the public.

  12. “I am active”: effects of a program to promote active aging

    Directory of Open Access Journals (Sweden)

    Mendoza-Ruvalcaba NM

    2015-05-01

    Full Text Available Neyda Ma Mendoza-Ruvalcaba,1 Elva Dolores Arias-Merino2 1Health Sciences Department, University of Guadalajara, University Center of Tonala Guadalajara, Jalisco, Mexico; 2Public Health Department, University of Guadalajara, University Center of Health Sciences, Guadalajara, Jalisco, Mexico Background: Active aging involves a general lifestyle strategy that allows preservation of both physical and mental health during the aging process. “I am Active” is a program designed to promote active aging by increased physical activity, healthy nutritional habits, and cognitive functioning. The purpose of this study was to assess the effectiveness of this program. Methods: Sixty-four healthy adults aged 60 years or older were recruited from senior centers and randomly allocated to an experimental group (n=31 or a control group (n=33. Baseline, post-test, and 6-month follow-up assessments were performed after the theoretical–practical intervention. Effect sizes were calculated. Results: At the conclusion of the program, the experimental group showed significant improvement compared with the control group in the following domains: physical activity (falls risk, balance, flexibility, self-efficacy, nutrition (self-efficacy and nutritional status, cognitive performance (processing speed and self-efficacy, and quality of life (general, health and functionality, social and economic status. Although some declines were reported, improvements at follow-up remained in self-efficacy for physical activity, self-efficacy for nutrition, and processing speed, and participants had better nutritional status and quality of life overall. Conclusion: Our findings show that this program promotes improvements in domains of active aging, mainly in self-efficacy beliefs as well as in quality of life in healthy elders. Keywords: active aging, successful aging, intervention program, randomized controlled trial

  13. Effect of Nb aggregates on Zr2Fe

    International Nuclear Information System (INIS)

    Ramos, Cinthia P.

    2001-01-01

    The binary Zr-Fe phase diagram revision, performed by Arias et al., accepted the intermetallic Zr 2 Fe crystalline structure as tetragonal and determined that the presence of a third element like oxygen, nitrogen or carbon, stabilizes a cubic phase. Nevitt et al. studying Ti, Zr and Hf alloys with transition metals as second or third element and ternary systems with oxygen as third element, systematized the occurrence of phases with a cubic Ti 2 Ni type crystalline structure. From previous studies in the Zr-Nb-Fe system, it is an agreed fact that Nb presence in the Zr 2 Fe intermetallic stabilizes a cubic Ti 2 Ni type phase. The purpose of the present work is to determine the stability range of the Zr 2 Fe intermetallic with Nb contents, the existence range of the ternary cubic Ti 2 Ni type phase (designated Λ) and the corresponding two-phase region. We analyze as cast and heat treated (800 C degrees) Zr-Nb-Fe alloys with 35 atomic % Fe and Nb contents between 0.5 and 15 atomic %. The determination and characterization of the phases is made by optical and scanning electron microscopy, X-ray diffraction microprobe analysis and Moessbauer Spectroscopy. Joining these techniques together it is found, among many other things, that the Zr 2 Fe phase would accept up to around 0.5 atomic % Nb in solution and that the two-phase region Zr 2 Fe+Λ would be stable in the (0.5 - 3.5) Nb atomic % range. It is proposed as well a 800 C degrees section of the ternary (Zr-Nb-Fe) in the studied region. (author) [es

  14. Atmospheric response in aurora experiment: Observations of E and F region neutral winds in a region of postmidnight diffuse aurora

    International Nuclear Information System (INIS)

    Larsen, M.F.; Marshall, T.R.; Mikkelsen, I.S.

    1995-01-01

    The goal of the Atmospheric Response in Aurora (ARIA) experiment carried out at Poker Flat, Alaska, on March 3, 1992, was to determine the response of the neutral atmosphere to the long-lived, large-scale forcing that is characteristic of the diffuse aurora in the postmidnight sector. A combination of chemical release rocket wind measurements, intrumented rocket composition measurements, and ground-based optical measurements were used to characterize the response of the neutral atmosphere. The rocket measurements were made at the end of a 90-min period of strong Joule heating. We focus on the neutral wind measurements made with the rocket. The forcing was determined by running the assimilated mapping of ionospheric electrodynamics (AMIE) analysis procedure developed at the National Center for Atmospheric Research. The winds expected at the latitude and longitude of the experiment were calculated using the spectral thermospheric general circulation model developed at the Danish Meteorological Institute. Comparisons of the observations and the model suggest that the neutral winds responded strongly in two height ranges. An eastward wind perturbation of ∼100 m s -1 developed between 140 and 200 km altitude with a peak near 160 km. A southwestward wind with peak magnitude of ∼150 m s -1 developed near 115 km altitude. The large amplitude winds at the lower altitude are particularly surprising. They appear to be associated with the upward propagating semidiurnal tide. However, the amplitude is much larger than predicted by any of the tidal models, and the shear found just below the peak in the winds was nomially unstable with a Richardson number of ∼0.08. 17 refs., 12 figs

  15. Service Quality Evaluation and Ranking of Container Terminal Operators

    Directory of Open Access Journals (Sweden)

    Jafar Sayareh

    2016-12-01

    Full Text Available In the service industry, the regular assessment of service quality is considered as a means of promoting the quality of services. Container market is no exception, and the quality of providing service in a container terminal is of prime importance in attracting new customers and maintaining the existing ones. The main aim of present research is to evaluate the quality of service being offered at Shahid Rajaee Container Terminal (SRCT in Bandar Abbas port. The evaluation process uses SERVQUAL model which is an appropriate tool for measuring the service quality, identifying and analyzing available gaps between service expectations and perceptions. Target population in this research includes customers of SRCT. The standard and customized questionnaires were distributed among 165 samples, out of which 127 (77% were returned. For the purpose of data analyses, initially the reliability of SERVQUAL model was checked, and then paired sample t-test was performed to reveal any possible gap between expectations and perceptions of respondents. Finally, TOPSIS was used to rank the 9 main container service companies in the SRCT. The results indicated that there are significant gaps between customers’ expectations and perceptions in SRCT, in all five dimensions of services quality. Additionally, from weighing point of view, ‘Tangibles’ was the most important dimension, followed by ‘Reliability’, ‘Assurance’, ‘Responsiveness’ and ‘Empathy’. In addition, ‘Tangibles’ dimension had maximum gap and ‘Empathy’ dimension had minimum gap between customers’ expectations and perceptions. Finally, after ranking companies, BandarAbbas Aria Container Terminal (BACT Company was ranked first among nine companies in satisfying customers’ expectations.

  16. Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options

    Directory of Open Access Journals (Sweden)

    Wang S

    2014-10-01

    Full Text Available Shelly Wang,1 Aria Fallah2,3 1Department of Neurosurgery, University of Toronto, Toronto, ON, Canada; 2Department of Neurosurgery, Miami Children’s Hospital, Miami, FL, USA; 3Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Abstract: Seizures are clinically significant manifestations associated with 79%–90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and cognitive development and carry significant individual and societal consequences. Prompt identification and treatment of seizures is an important focus in the overall management of tuberous sclerosis complex patients. Medical management, either after seizure onset or prophylactically in infants with electroencephalographic abnormalities, is considered first-line therapy. Vigabatrin and adrenocorticotropic hormone have emerged over the past few decades as mainstay pharmacologic modalities. Furthermore, emerging research on mammalian target of rapamycin inhibitors demonstrated promise for the management of seizures and subependymal giant cell astrocytoma. For appropriate surgical candidates with an epileptogenic zone associated with one or more glioneuronal hamartomas, ideally in noneloquent cortex, resective surgery can be considered, which provides a cure in 56% of patients. For medically refractory patients who do not meet criteria for curative surgery, palliative surgical approaches focused on reducing seizure burden, in the form of corpus callosotomy and vagus nerve stimulation, are alternative management options. Lastly, the ketogenic diet, a reemerging therapy based on the anticonvulsant effects of ketone bodies, can be utilized independently or in conjunction with other treatment modalities for the management of difficult-to-treat seizures. Keywords: epilepsy, adrenocorticotropic hormone, vigabatrin, mammalian

  17. Participant Action Research and Environmental Education

    Directory of Open Access Journals (Sweden)

    Yasmin Coromoto Requena Bolívar

    2018-02-01

    Full Text Available The committed participation of the inhabitants in diverse Venezuelan communities is fundamental in the search of solution to environmental problems that they face in the daily life; in the face of this reality, studies based on Participant Action Research were addressed, through a review and documentary analysis of four works related to community participation, carried out in the state of Lara. For this, the following question was asked: ¿What was the achievement in the solution of environmental problems in the communities, reported through the master's degree works oriented under participant action research and presented to Yacambú University in 2011-2013? A qualitative approach is used, approaching the information according to the stages suggested by Arias (2012: Search of sources, initial reading of documents, preparation of the preliminary scheme, data collection, analysis and interpretation of the information, formulation of the final scheme, introduction and conclusions, final report. It begins with the definition of the units of analysis and inquiry of the literature, through theoretical positions, concepts and contributions on: participant action research, participation and environmental education, to culminate with the analysis and interpretation of the information and the conclusions of this investigation. For the collection of the data, the bibliographic records were used with the purpose of organizing the information on the researches consulted, and of summary for the synthesis of the documents. It was concluded that, in the analyzed degree works, the purpose of the IAP was fulfilled, which consisted in the transformation of the problem-situation, which allowed the IAP to become the propitious scenario to promote environmental participation and education not formal.

  18. A new method for the realistic estimation of seismic ground motion in megacities: The case of Rome

    International Nuclear Information System (INIS)

    Faeh, D.; Iodice, C.; Suhadole, P.; Panza, G.F.

    1994-04-01

    A hybrid technique, based on mode summation and finite differences, is used to simulate the ground motion induced in the city of Rome by the January 13, 1915, Fucino (Italy) earthquake (M=6.9). The technique allows us to take into consideration source, path, and local soil effects. The results of the numerical simulations are used for a comparison between the observed distribution of damage in Rome, and certain quantities related to the computed ground motion. These quantities are those commonly used for engineering purposes, e.g. the peak ground acceleration, the maximum response of a simple oscillator, and the so-called ''total energy of ground motion'' which is related to the Arias Intensity. Integral quantities of the computed time-series, such as the total energy of ground motion, are in good agreement with the observed distribution of damage and turn out to give a good representation of the ground motion. From the computation of spectral ratios, it has been recognised that the presence of a near-surface layer of rigid material is not sufficient to classify a location as a ''hard-rock site'' when the rigid material has a sedimentary complex below it. This is because the underlying sedimentary complex causes amplifications due to resonances. Within sedimentary basins, incident energy in certain frequency bands can also be shifted from the vertical, into the radial component of motion. This phenomenon is very localized, both in frequency and space, and closely neighboring sites can be characterized by very large differences in the seismic response, even if the lateral variations of local soil conditions are relatively smooth. (author). Refs, 12 figs, 1 tab

  19. Thermomechanical analysis of a SPX 1 type sodium-air heat exchanger. Analisi termomeccanica di scambiatore sodio-aria (tipo SPX 1): comportamento della macchina e dei relativi tubi alettati

    Energy Technology Data Exchange (ETDEWEB)

    Cesari, F; Menghini, S; Piolanti, G

    1981-08-15

    A description is given of a mathematical model for simulating the thermohydraulics of a heat exchanger. Temperature distribution is determined for stationary and transient function. An analysis is made of the pipelines in which the sodium circulates. 9 references.

  20. An observational study to assess if automated diabetic retinopathy image assessment software can replace one or more steps of manual imaging grading and to determine their cost-effectiveness.

    Science.gov (United States)

    Tufail, Adnan; Kapetanakis, Venediktos V; Salas-Vega, Sebastian; Egan, Catherine; Rudisill, Caroline; Owen, Christopher G; Lee, Aaron; Louw, Vern; Anderson, John; Liew, Gerald; Bolter, Louis; Bailey, Clare; Sadda, SriniVas; Taylor, Paul; Rudnicka, Alicja R

    2016-12-01

    Diabetic retinopathy screening in England involves labour-intensive manual grading of retinal images. Automated retinal image analysis systems (ARIASs) may offer an alternative to manual grading. To determine the screening performance and cost-effectiveness of ARIASs to replace level 1 human graders or pre-screen with ARIASs in the NHS diabetic eye screening programme (DESP). To examine technical issues associated with implementation. Observational retrospective measurement comparison study with a real-time evaluation of technical issues and a decision-analytic model to evaluate cost-effectiveness. A NHS DESP. Consecutive diabetic patients who attended a routine annual NHS DESP visit. Retinal images were manually graded and processed by three ARIASs: iGradingM (version 1.1; originally Medalytix Group Ltd, Manchester, UK, but purchased by Digital Healthcare, Cambridge, UK, at the initiation of the study, purchased in turn by EMIS Health, Leeds, UK, after conclusion of the study), Retmarker (version 0.8.2, Retmarker Ltd, Coimbra, Portugal) and EyeArt (Eyenuk Inc., Woodland Hills, CA, USA). The final manual grade was used as the reference standard. Arbitration on a subset of discrepancies between manual grading and the use of an ARIAS by a reading centre masked to all grading was used to create a reference standard manual grade modified by arbitration. Screening performance (sensitivity, specificity, false-positive rate and likelihood ratios) and diagnostic accuracy [95% confidence intervals (CIs)] of ARIASs. A secondary analysis explored the influence of camera type and patients' ethnicity, age and sex on screening performance. Economic analysis estimated the cost per appropriate screening outcome identified. A total of 20,258 patients with 102,856 images were entered into the study. The sensitivity point estimates of the ARIASs were as follows: EyeArt 94.7% (95% CI 94.2% to 95.2%) for any retinopathy, 93.8% (95% CI 92.9% to 94.6%) for referable retinopathy and 99

  1. Mini-pleat filters for improved indoor air quality. Filtri a 'piccole pieghe' per una migliore qualita' dell'aria negli ambienti civili e negli impianti industriali

    Energy Technology Data Exchange (ETDEWEB)

    Zucchelli, D.

    1992-07-01

    Advanced manufacturing techniques applied to the fabrication of air filters have led to the creation of a high quality/efficiency mini-pleat filter which, however, has yet to see wide use in commercial space heating ventilation and air conditioning systems. Now, with greater attention being given to indoor air quality, these high performance filters should see greater market demand. This paper discusses the design and performance characteristics of mini-pleat filters and surveys the range of models currently available on the market.

  2. System for continuous real time air monitoring by means of gamma spectrometry with germanium dosimeter; Sistema di monitoraggio dell'aria in continuo mediante spettrometria gamma con rilevatore al germanio

    Energy Technology Data Exchange (ETDEWEB)

    Montalto, M; Giacomelli, R; Nocente, M; Bortoluzzi, S; Spezzano, P [ENEA - Area Energia, Ambiente e Salute, Centro Ricerche Energia Saluggia, Vercelli (Italy)

    1990-12-15

    Design of automatic system for real time air monitoring of radioactive particulates are relate. Recommendations are made for design and operation of sampling conduits to minimize losses. By means of experimental equipment loss of particles in long sampling conduits, minimum detectable activity and efficiency of gamma radiation detectable are evaluated. (author)

  3. SU-E-J-16: Automatic Image Contrast Enhancement Based On Automatic Parameter Optimization for Radiation Therapy Setup Verification

    International Nuclear Information System (INIS)

    Qiu, J; Li, H. Harlod; Zhang, T; Yang, D; Ma, F

    2015-01-01

    Purpose: In RT patient setup 2D images, tissues often cannot be seen well due to the lack of image contrast. Contrast enhancement features provided by image reviewing software, e.g. Mosaiq and ARIA, require manual selection of the image processing filters and parameters thus inefficient and cannot be automated. In this work, we developed a novel method to automatically enhance the 2D RT image contrast to allow automatic verification of patient daily setups as a prerequisite step of automatic patient safety assurance. Methods: The new method is based on contrast limited adaptive histogram equalization (CLAHE) and high-pass filtering algorithms. The most important innovation is to automatically select the optimal parameters by optimizing the image contrast. The image processing procedure includes the following steps: 1) background and noise removal, 2) hi-pass filtering by subtracting the Gaussian smoothed Result, and 3) histogram equalization using CLAHE algorithm. Three parameters were determined through an iterative optimization which was based on the interior-point constrained optimization algorithm: the Gaussian smoothing weighting factor, the CLAHE algorithm block size and clip limiting parameters. The goal of the optimization is to maximize the entropy of the processed Result. Results: A total 42 RT images were processed. The results were visually evaluated by RT physicians and physicists. About 48% of the images processed by the new method were ranked as excellent. In comparison, only 29% and 18% of the images processed by the basic CLAHE algorithm and by the basic window level adjustment process, were ranked as excellent. Conclusion: This new image contrast enhancement method is robust and automatic, and is able to significantly outperform the basic CLAHE algorithm and the manual window-level adjustment process that are currently used in clinical 2D image review software tools

  4. A coupled transport and solid mechanics formulation with improved reaction kinetics parameters for modeling oxidation and decomposition in a uranium hydride bed.

    Energy Technology Data Exchange (ETDEWEB)

    Salloum, Maher N.; Shugard, Andrew D.; Kanouff, Michael P.; Gharagozloo, Patricia E.

    2013-03-01

    Modeling of reacting flows in porous media has become particularly important with the increased interest in hydrogen solid-storage beds. An advanced type of storage bed has been proposed that utilizes oxidation of uranium hydride to heat and decompose the hydride, releasing the hydrogen. To reduce the cost and time required to develop these systems experimentally, a valid computational model is required that simulates the reaction of uranium hydride and oxygen gas in a hydrogen storage bed using multiphysics finite element modeling. This SAND report discusses the advancements made in FY12 (since our last SAND report SAND2011-6939) to the model developed as a part of an ASC-P&EM project to address the shortcomings of the previous model. The model considers chemical reactions, heat transport, and mass transport within a hydride bed. Previously, the time-varying permeability and porosity were considered uniform. This led to discrepancies between the simulated results and experimental measurements. In this work, the effects of non-uniform changes in permeability and porosity due to phase and thermal expansion are accounted for. These expansions result in mechanical stresses that lead to bed deformation. To describe this, a simplified solid mechanics model for the local variation of permeability and porosity as a function of the local bed deformation is developed. By using this solid mechanics model, the agreement between our reacting bed model and the experimental data is improved. Additionally, more accurate uranium hydride oxidation kinetics parameters are obtained by fitting the experimental results from a pure uranium hydride oxidation measurement to the ones obtained from the coupled transport-solid mechanics model. Finally, the coupled transport-solid mechanics model governing equations and boundary conditions are summarized and recommendations are made for further development of ARIA and other Sandia codes in order for them to sufficiently implement the model.

  5. Structural studies of SpoIIAA using NMR

    International Nuclear Information System (INIS)

    Comfort, D.M.

    1998-01-01

    The protein SpoIIAA participates, via phosphorylation and dephosphorylation, in the four-component system that regulates the sporulation sigma factor e. Differential gene expression depends on specialised transcription factors called sigma factors, which direct the RNA polymerase to transcribe specific genes in one or other of the two chambers at various stages of sporulation. The first sporulation-specific sigma factor to be activated is 4 transcription that depends on σ F is essential for the remaining sigma factors to become active in turn. Early in sporulation SpoIIAA is in the phosphorylated state (SpoIIAA-P), as a result of the activity of the ATP-dependent protein kinase, SpoIIAB. About 80 minutes after the initiation of sporulation a specific phosphatase, SpoIIE, begins to hydrolyse SpoIIAA-P, and the resulting SpoIIAA again becomes a substrate for SpoIIAB. SpoIIAB is also an anti-sigma factor which in its free form inhibits a F by binding to it. Competition by SpoIIAA (the anti-anti-sigma factor) for binding to SpoIIAB releases e activity. The three-dimensional structure of SpoIIAA has been determined using high resolution NMR. SpoIIAA has a novel fold, composed of a-helices and P-strand elements. The structural differences between SpoIIAA and its inactive form, SpoIIAA-P, were also investigated by NMR. Tentative evidence points to the observation that phosphorylation of SpoIIAA results in a minor conformational change near the site of phosphorylation, which interferes with the hydrophobic interaction between SpoIIAA and SpoIIAB. Further NMR studies helped to predict the location of SpoIIAA-, GTP-, and ATP-binding sites on the SpoIIAA structure. In addition, the automated iterative NOE assignment algorithm, ARIA, was used to obtain additional NOE-based distance constraints and to calculate a refined structure. (author)

  6. Structural studies of SpoIIAA using NMR

    Energy Technology Data Exchange (ETDEWEB)

    Comfort, D.M

    1998-07-01

    The protein SpoIIAA participates, via phosphorylation and dephosphorylation, in the four-component system that regulates the sporulation sigma factor e. Differential gene expression depends on specialised transcription factors called sigma factors, which direct the RNA polymerase to transcribe specific genes in one or other of the two chambers at various stages of sporulation. The first sporulation-specific sigma factor to be activated is 4 transcription that depends on {sigma}{sup F} is essential for the remaining sigma factors to become active in turn. Early in sporulation SpoIIAA is in the phosphorylated state (SpoIIAA-P), as a result of the activity of the ATP-dependent protein kinase, SpoIIAB. About 80 minutes after the initiation of sporulation a specific phosphatase, SpoIIE, begins to hydrolyse SpoIIAA-P, and the resulting SpoIIAA again becomes a substrate for SpoIIAB. SpoIIAB is also an anti-sigma factor which in its free form inhibits a F by binding to it. Competition by SpoIIAA (the anti-anti-sigma factor) for binding to SpoIIAB releases e activity. The three-dimensional structure of SpoIIAA has been determined using high resolution NMR. SpoIIAA has a novel fold, composed of a-helices and P-strand elements. The structural differences between SpoIIAA and its inactive form, SpoIIAA-P, were also investigated by NMR. Tentative evidence points to the observation that phosphorylation of SpoIIAA results in a minor conformational change near the site of phosphorylation, which interferes with the hydrophobic interaction between SpoIIAA and SpoIIAB. Further NMR studies helped to predict the location of SpoIIAA-, GTP-, and ATP-binding sites on the SpoIIAA structure. In addition, the automated iterative NOE assignment algorithm, ARIA, was used to obtain additional NOE-based distance constraints and to calculate a refined structure. (author)

  7. Characterization of the Complete Nucleotide Sequences of IncA/C2 Plasmids Carrying In809-Like Integrons from Enterobacteriaceae Isolates of Wildlife Origin.

    Science.gov (United States)

    Papagiannitsis, Costas C; Kutilova, Iva; Medvecky, Matej; Hrabak, Jaroslav; Dolejska, Monika

    2017-09-01

    A total of 18 Enterobacteriaceae (17 from gulls and 1 from a clinical sample) collected from Australia, carrying IncA/C plasmids with the IMP-encoding In809-like integrons, were studied. Seven plasmids, being representatives of different origins, plasmid sizes, replicon combinations, and resistance genes, were completely sequenced. Plasmid pEc158, identified in a clinical Escherichia coli ST752 isolate, showed extensive similarity to type 2 IncA/C 2 plasmids. pEc158 carried none of the bla CMY-2 -like region or ARI-B and ARI-A regions, while it contained a hybrid transposon structure. The six remaining plasmids, which were of wildlife origin, were highly similar to each other and probably were fusion derivatives of type 1 and type 2 A/C 2 plasmids. The latter plasmids contained an ARI-B region and hybrid transposon structures. In all plasmids, hybrid transposon structures containing In809-like integrons were inserted 3,434 bp downstream of the rhs2 start codon. In all cases, the one outermost 38-bp inverted repeat (IR) of the transposon was associated with the Tn 1696 tnp module, while the other outermost 38-bp IR of the transposon was associated with either a Tn 6317 -like module or a Tn 21 mer module. However, the internal structure of the transposon and the resistance genes were different in each plasmid. These findings indicated that, for the specific periods of time and settings, different IncA/C 2 plasmid types carrying In809-like elements circulated among isolates of wildlife and clinical origins. Additionally, they provided the basis for speculations regarding the reshuffling of IncA/C 2 plasmids with In809-like integrons and confirmed the rapid evolution of IncA/C 2 plasmid lineages. Copyright © 2017 American Society for Microbiology.

  8. Mechanisms Involved in Acquisition of blaNDM Genes by IncA/C2 and IncFIIY Plasmids.

    Science.gov (United States)

    Wailan, Alexander M; Sidjabat, Hanna E; Yam, Wan Keat; Alikhan, Nabil-Fareed; Petty, Nicola K; Sartor, Anna L; Williamson, Deborah A; Forde, Brian M; Schembri, Mark A; Beatson, Scott A; Paterson, David L; Walsh, Timothy R; Partridge, Sally R

    2016-07-01

    blaNDM genes confer carbapenem resistance and have been identified on transferable plasmids belonging to different incompatibility (Inc) groups. Here we present the complete sequences of four plasmids carrying a blaNDM gene, pKP1-NDM-1, pEC2-NDM-3, pECL3-NDM-1, and pEC4-NDM-6, from four clinical samples originating from four different patients. Different plasmids carry segments that align to different parts of the blaNDM region found on Acinetobacter plasmids. pKP1-NDM-1 and pEC2-NDM-3, from Klebsiella pneumoniae and Escherichia coli, respectively, were identified as type 1 IncA/C2 plasmids with almost identical backbones. Different regions carrying blaNDM are inserted in different locations in the antibiotic resistance island known as ARI-A, and ISCR1 may have been involved in the acquisition of blaNDM-3 by pEC2-NDM-3. pECL3-NDM-1 and pEC4-NDM-6, from Enterobacter cloacae and E. coli, respectively, have similar IncFIIY backbones, but different regions carrying blaNDM are found in different locations. Tn3-derived inverted-repeat transposable elements (TIME) appear to have been involved in the acquisition of blaNDM-6 by pEC4-NDM-6 and the rmtC 16S rRNA methylase gene by IncFIIY plasmids. Characterization of these plasmids further demonstrates that even very closely related plasmids may have acquired blaNDM genes by different mechanisms. These findings also illustrate the complex relationships between antimicrobial resistance genes, transposable elements, and plasmids and provide insights into the possible routes for transmission of blaNDM genes among species of the Enterobacteriaceae family. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  9. Book Reviews | Reseñas

    Directory of Open Access Journals (Sweden)

    Book Review Editor, Barbara Hogenboom

    2013-10-01

    Full Text Available Violent Democracies in Latin America, edited by Enrique Desmond Arias and Daniel M. Goldstein; reviewed by Rivke Jaffe, p. 124Violence, Coercion, and State-Making in Twentieth Century Mexico. The Other Half of the Centaur, edited by Wil Pansters; reviewed by Markus-Michael Müller, p. 126Police Reform in Mexico. Informal Politics and the Challenge of Institutional Change, by Daniel M. Sabet; reviewed by Wil G. Pansters, p. 128Bribes, Bullets and Intimidation: Drug Trafficking and the Law in Central America, by Julie Marie Bunck and Michael Ross Fowler; reviewed by Sonja Wolf, p. 132Latin American Urban Development into the 21st Century: Towards a Renewed Perspective on the City, edited by Dennis Rodgers, Jo Beall and Ravi Kanbur; reviewed by Christien Klaufus, p. 133Latin America’s Turbulent Transitions: The Future of Twenty-First Century Socialism, by Roger Burbach, Michael Fox and Federico Fuentes; reviewed by Barry Cannon, p. 136Cuba and Its Neighbours: Democracy in Motion, by Arnold August; reviewed by Antonio Carmona Báez, p. 138Bolivia: Processes of Change, by John Crabtree and Ann Chaplin; reviewed by Gonzalo Rojas-Ortuste, p. 140The Rise of Ethnic Politics in Latin America, by Raúl L. Madrid; reviewed by Ton Salman, 142Intimate Indigeneities. Race, Sex, and History in the Small Spaces of Andean Life, by Andrew Canessa; reviewed by Annelou Ypeij, p. 145¡Américas Unidas! Nelson A. Rockefeller’s Office of Inter-American Affairs (1940-1946, edited by Gisela Cramer and Ursula Prutsch; reviewed by Darlene J. Sadlier, p. 146How a Revolutionary Art became Official Culture: Murals, Museums, and the Mexican State, by Mary Coffey; reviewed by Paula López Caballero, p. 148Sugar, Slavery, Christianity and the Making of Race, by Mark Edelman Boren; reviewed by Gert Oostindie, p. 150

  10. Acoustic characteristics of modern Greek Orthodox Church music.

    Science.gov (United States)

    Delviniotis, Dimitrios S

    2013-09-01

    Some acoustic characteristics of the two types of vocal music of the Greek Orthodox Church Music, the Byzantine chant (BC) and ecclesiastical speech (ES), are studied in relation to the common Greek speech and the Western opera. Vocal samples were obtained, and their acoustic parameters of sound pressure level (SPL), fundamental frequency (F0), and the long-time average spectrum (LTAS) characteristics were analyzed. Twenty chanters, including two chanters-singers of opera, sang (BC) and read (ES) the same hymn of Byzantine music (BM), the two opera singers sang the same aria of opera, and common speech samples were obtained, and all audio were analyzed. The distribution of SPL values showed that the BC and ES have higher SPL by 9 and 12 dB, respectively, than common speech. The average F0 in ES tends to be lower than the common speech, and the smallest standard deviation (SD) of F0 values characterizes its monotonicity. The tone-scale intervals of BC are close enough to the currently accepted theory with SD equal to 0.24 semitones. The rate and extent of vibrato, which is rare in BC, equals 4.1 Hz and 0.6 semitones, respectively. The average LTAS slope is greatest in BC (+4.5 dB) but smaller than in opera (+5.7 dB). In both BC and ES, instead of a singer's formant appearing in an opera voice, a speaker's formant (SPF) was observed around 3300 Hz, with relative levels of +6.3 and +4.6 dB, respectively. The two vocal types of BM, BC, and ES differ both to each other and common Greek speech and opera style regarding SPL, the mean and SD of F0, the LTAS slope, and the relative level of SPF. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  11. REVIEW OF RIJEKA’S WRITER GINO ANTONY’S (CAVALIERE DI GARBO WORKS THROUGH A PRESS SECTION OF ITALIAN PERIODICALS

    Directory of Open Access Journals (Sweden)

    Dolores Miškulin

    2013-01-01

    Full Text Available Gino Antony (Trieste, 1877 – Casalecchio sul Reno, 1948 was a poet, prose writer and playwright. Although he was born in Trieste, he was considered an adoptive of Rijeka as he had lived there almost all his life. As a student in Siena he published a collection of poems Fiori di campo (1899. In Rijeka he started publishing texts in ‘La Voce del Popolo’ in which he described urban conditions and he was a successful writer of ‘elzevirs’ dealing with different topics of urban life. His main interest was related to the theatre and music. He was an animator of the arts club Società Filarmonico-drammatica, the centre from which Rijeka cultural irredentism radiated. He wrote five comedies in Italian: Eroi senza gloria (1904, Poveri illusi (1905, La prima e l’ultima (1905, Aria nuova (1905 and Anime schiave (1906. He also wrote two dialectal comedies (El ritorno and El zogo that, unfortunately, were never published. However, Antony was better known as a dialectal poet. So he took the pseudonym ‘Cavaliere di Garbo’, and the editor Battara (1907 published his dialectal collection Sonetti fiumani which represents his most significant contribution to the history of Rijeka literature. His sonnets were often published in the Rijeka press of that time, and a great many of them were inspired by the daily politics. In them, the author masterfully uses different registers: descriptive, sentimental, nostalgic, and critical, in a kind of distorted or purified dialect. Since not all of Gino Antony’s works are available today, the aim of this paper is to provide an insight into his works through a press section of Italian periodicals from this period.

  12. SU-E-J-16: Automatic Image Contrast Enhancement Based On Automatic Parameter Optimization for Radiation Therapy Setup Verification

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, J [Taishan Medical University, Taian, Shandong (China); Washington University in St Louis, St Louis, MO (United States); Li, H. Harlod; Zhang, T; Yang, D [Washington University in St Louis, St Louis, MO (United States); Ma, F [Taishan Medical University, Taian, Shandong (China)

    2015-06-15

    Purpose: In RT patient setup 2D images, tissues often cannot be seen well due to the lack of image contrast. Contrast enhancement features provided by image reviewing software, e.g. Mosaiq and ARIA, require manual selection of the image processing filters and parameters thus inefficient and cannot be automated. In this work, we developed a novel method to automatically enhance the 2D RT image contrast to allow automatic verification of patient daily setups as a prerequisite step of automatic patient safety assurance. Methods: The new method is based on contrast limited adaptive histogram equalization (CLAHE) and high-pass filtering algorithms. The most important innovation is to automatically select the optimal parameters by optimizing the image contrast. The image processing procedure includes the following steps: 1) background and noise removal, 2) hi-pass filtering by subtracting the Gaussian smoothed Result, and 3) histogram equalization using CLAHE algorithm. Three parameters were determined through an iterative optimization which was based on the interior-point constrained optimization algorithm: the Gaussian smoothing weighting factor, the CLAHE algorithm block size and clip limiting parameters. The goal of the optimization is to maximize the entropy of the processed Result. Results: A total 42 RT images were processed. The results were visually evaluated by RT physicians and physicists. About 48% of the images processed by the new method were ranked as excellent. In comparison, only 29% and 18% of the images processed by the basic CLAHE algorithm and by the basic window level adjustment process, were ranked as excellent. Conclusion: This new image contrast enhancement method is robust and automatic, and is able to significantly outperform the basic CLAHE algorithm and the manual window-level adjustment process that are currently used in clinical 2D image review software tools.

  13. The epidemiology of hip fractures across western Victoria, Australia.

    Science.gov (United States)

    Holloway, Kara L; Sajjad, Muhammad A; Mohebbi, Mohammadreza; Kotowicz, Mark A; Livingston, Patricia M; Khasraw, Mustafa; Hakkennes, Sharon; Dunning, Trisha L; Brumby, Susan; Page, Richard S; Pedler, Daryl; Sutherland, Alasdair; Venkatesh, Svetha; Brennan-Olsen, Sharon L; Williams, Lana J; Pasco, Julie A

    2018-03-01

    Hip fractures are associated with considerable morbidity and mortality. Hip fracture incidence varies across different levels of accessibility/remoteness and socioeconomic status (SES). As part of the Ageing, Chronic Disease and Injury Study, we aimed to map the pattern of hip fractures across the western region of the Australian state of Victoria, which contains a range of remoteness levels and SES. Data on hip fractures resulting in hospital admission were extracted from the Victorian Admitted Episodes Dataset (VAED) for men and women aged 40+years during 2010-2013 inclusive. An age-adjusted incidence rate (per 10,000population/year) was calculated for the entire region. Crude incidence rates and length of acute care hospital stay (excluding rehabilitation) were calculated for each Local Government Area (LGA). The impact of aggregated age, accessibility/remoteness index of Australia (ARIA) and SES on hip fracture rates aggregated across LGAs was determined using Poisson regression. For men, the age-standardised rate of hospitalisations for hip fracture across the whole region was 19.2 per 10,000population/year (95%CI 18.0-20.4) and for women, 40.0 (95%CI 38.3-41.7). The highest incidence rates for both sexes occurred in the less accessible LGAs of Yarriambiack and Hindmarsh, as well as the LGA with the lowest SES, Central Goldfields. In both sexes, approximately two thirds of individuals were discharged from acute hospital care within 14days. Increasing age, higher remoteness and lower SES were all associated with higher hip fracture rates. Crude incidence rates varied by location. Given that a high proportion of patients had acute hospital care of ≤14days, and accessibility and SES were associated with hip fracture rates, these results can inform policy and provide a model for other groups to conduct similar research in their local environment. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. SU-E-T-139: Automated Daily EPID Exit Dose Analysis Uncovers Treatment Variations

    Energy Technology Data Exchange (ETDEWEB)

    Olch, A [University of Southern California, Los Angeles, CA (United States)

    2015-06-15

    Purpose: To evaluate a fully automated EPID exit dose system for its ability to detect daily treatment deviations including patient setup, delivery, and anatomy changes. Methods: PerFRACTION (Sun Nuclear Corporation) software is a system that uses integrated EPID images taken during patient treatment and automatically pulled from the Aria database and analyzed based on user-defined comparisons. This was used to monitor 20 plans consisting of a total of 859 fields for 18 patients, for a total of 251 fractions. Nine VMAT, 5 IMRT, and 6 3D plans were monitored. The Gamma analysis was performed for each field within a plan, comparing the first fraction against each of the other fractions in each treatment course. A 2% dose difference, 1 mm distance-to-agreement, and 10% dose threshold was used. These tight tolerances were chosen to achieve a high sensitivity to treatment variations. The field passed if 93% of the pixels had a Gamma of 1 or less. Results: Twenty-nine percent of the fields failed. The average plan passing rate was 92.5%.The average 3D plan passing rate was less than for VMAT or IMRT, 84%, vs. an average of 96.2%. When fields failed, an investigation revealed changes in patient anatomy or setup variations, often also leading to variations of transmission through immobilization devices. Conclusion: PerFRACTION is a fully automated system for determining daily changes in dose transmission through the patient that requires no effort other than for the imager panel to be deployed during treatment. A surprising number of fields failed the analysis and can be attributed to important treatment variations that would otherwise not be appreciated. Further study of inter-fraction treatment variations is possible and warranted. Sun Nuclear Corporation provided a license to the software described.

  15. «Governem-se vocês mesmos!» democracia e carnificina no norte de Moçambique

    Directory of Open Access Journals (Sweden)

    Harry G. West

    2008-04-01

    Full Text Available A linguagem de poder que os habitantes do planalto de Mueda falaram ao longo da transformação neoliberal da economia e política moçambicanas difere substancialmente da linguagem falada pelos reformadores democráticos, apesar dos pontos de convergência e das variações internas em ambas as linguagens. Na disjunção entre elas, os muedenses relacionaram-se criticamente com o processo de democratização em curso, articulando a sua própria visão acerca do funcionamento do poder no mundo que habitam. Equiparações à primeira vista paradoxais - como entre descentralização democrática e abandono por parte do Estado, entre liberdade individual e perigo colectivo de feitiçaria, ou entre democracia e carnificina - constituíram, afinal, formas em última instância democráticas de avaliação e de crítica às transformações ocorridas e às formas como o poder é exercido no novo contexto de capitalismo neoliberal.The language of power spoken by the inhabitants of the Mueda plateau in the course of the neoliberal transformation of Mozambican political and economic life is substantially different to the language spoken by democratic reformers, despite the commonalities and internal variations in both languages. In the rift between the languages, the Muedans adopt a critical stance towards the current process of democratization, articulating their own vision of how power operates in their world. Equivalences which are at first sight paradoxical - such as equating democratic decentralization with abandonment by the state, individual freedom with the collective danger of witchcraft, and democracy with carnage - were ultimately democratic ways of evaluating and criticizing the changes taking place and the ways in which power is used in the new context of neoliberal capitalism.

  16. Valoración psicométrica de la Psychological Entitlement Scale desde la Teoría Clásica de los Tests y la Teoría de Respuesta al Ítem

    Directory of Open Access Journals (Sweden)

    Débora Jeannete Mola

    2013-01-01

    Full Text Available Objetivo. Esta investigación se propuso examinar las propiedades psicométricas de la escala P sychological Entitlement Scale (PES en el contexto local desde la Teoría clásica de los tests (TCT y la Teoría de respuesta al ítem (TRI. Método. Participaron 402 estudiantes universitarios con una media de edad de 22.7 7 años ( DS = 4.85, de ambos géneros (61.9% mujeres y de distintas carreras universit arias y 324 personas de 18 a 65 años de edad ( M = 32.77, DS = 10.71, de ambos géneros (56.2 % mujeres y de diferentes niveles socioeconómicos, residentes en la ciudad de Córdoba, seleccionados de manera accid ental. Todos ellos fueron evaluados con la PES y la Escala de dominancia triple. Resultados. Desde la TCT, análisis factoriales exploratorios y confirmatorios evidenciaron que ocho de los nueve ítems que co mprendía la escala original mostraron una estructura unifactorial, con adecuadas cargas factoriales y/o pesos de regresión. Además, se observaron valores aceptables de consistencia interna. Las personas clasificadas como prosociales presentaron valores significativamente menores en la PES que las personas individualistas y competitivas ( Ș p 2 = 0.04. Desde la TRI, si bien se obtuvo un buen ajuste global al modelo de escalas de clasificación de un parámetro, el análisis de ítems evidenció índices inaceptables para un ítem y categorías po co informativas. Conclusión. Aunque se obtuvo evidencia sobre adecuadas propiedades psicométricas desde la TCT , análisis desde la TRI sugieren realizar ajustes al instrumento, en particular, reagrupar categorías de respuest a que resultaron poco informativas.

  17. DC type 2 polarization depends on both the allergic status of the individual and protease activity of Per a 10.

    Science.gov (United States)

    Goel, Chhavi; Gaur, S N; Bhati, Gaurav; Arora, Naveen

    2015-10-01

    Cockroach proteases are important risk factors for asthma development in predisposed individuals. In the present study, effect of allergic status of patients on DCs polarization in response to protease allergen Per a 10 was investigated. Cockroach-allergic, other-allergic patients and healthy individuals were selected following the guidelines of ATS/ARIA. Monocyte-derived dendritic cells (DCs) were generated from the selected individuals and stimulated with Per a 10. Flow cytometric analysis showed a significantly high expression of CD80 and CD86 on DCs from cockroach-allergic patients after Per a 10 stimulation as compared to healthy individuals or other-allergic patients (PPer a 10 induced comparable level of CD83 expression on DCs from all the 3 groups, showing it was irrespective of the allergic status. CD40 expression was significantly low (PPer a 10 induced lower CD40 expression on DCs than the heat-inactivated Per a 10 (PPer a 10 stimulated DC cultures was significantly higher than in heat-inactivated Per a 10 (PPer a 10-stimulated DCs than heat-inactivated Per a 10-stimulated DCs. Per a 10-stimulated DCs from cockroach-allergic patients secreted high levels of IL-5, IL-6, TNF-α than that from healthy individuals or other-allergic patients (PPer a 10-stimulated DCs from cockroach-allergic patients induced increased secretions of IL-4, IL-5, IL-6, TNF-α and low IL-12 by T cells as compared to those from other groups (PPer a 10 allergen, polarization of DCs shifts toward type 2 in cockroach-allergic patients but not in the healthy individuals or other-allergic patients. In conclusion, both allergic status of the individual and protease activity of Per a 10 are important parameters that participate in DCs polarization. Copyright © 2015 Elsevier GmbH. All rights reserved.

  18. Is it sufficient to repeat LINEAR accelerator stereotactic radiosurgery in choroidal melanoma?

    Science.gov (United States)

    Furdova, A; Horkovicova, K; Justusova, P; Sramka, M

    One day session LINAC based stereotactic radiosurgery (SRS) at LINAC accelerator is a method of "conservative" attitude to treat the intraocular malignant uveal melanoma. We used model Clinac 600 C/D Varian (system Aria, planning system Corvus version 6.2 verification IMRT OmniPro) with 6 MeV X by rigid immobilization of the eye to the Leibinger frame. The stereotactic treatment planning after fusion of CT and MRI was optimized according to the critical structures (lens, optic nerve, also lens and optic nerve at the contralateral side, chiasm). The first plan was compared and the best plan was applied for therapy at C LINAC accelerator. The planned therapeutic dose was 35.0 Gy by 99 % of DVH (dose volume histogram). In our clinical study in the group of 125 patients with posterior uveal melanoma treated with SRS, in 2 patients (1.6 %) was repeated SRS indicated. Patient age of the whole group ranged from 25 to 81 years with a median of 54 TD was 35.0 Gy. In 2 patients after 5 year interval after stereotactic radiosurgery for uveal melanoma stage T1, the tumor volume increased to 50 % of the primary tumor volume and repeated SRS was necessary. To find out the changes in melanoma characteristics after SRS in long term interval after irradiation is necessary to follow up the patient by an ophthalmologist regularly. One step LINAC based stereotactic radiosurgery with a single dose 35.0 Gy is one of treatment options to treat T1 to T3 stage posterior uveal melanoma and to preserve the eye globe. In some cases it is possible to repeat the SRS after more than 5 year interval (Fig. 8, Ref. 23).

  19. Effetti dei blocchi totali del traffico motorizzato sulla concentrazione dei principali inquinamenti atmosferici

    Directory of Open Access Journals (Sweden)

    C. Signorelli

    2003-05-01

    Full Text Available

    Obiettivi: il contenimento degli inquinamenti atmosferici attraverso blocchi parziali e totali dei veicoli circolanti nelle aree critiche è un tema molto dibattuto negli ultimi anni, soprattutto in relazione all’efficacia a breve e medio termine di questi provvedimenti sulla concentrazione degli inquinanti nell’aria. Sulla base dei dati diffusi dall’ARPA della Regione Lombardia sono stati analizzati gli effetti di due blocchi totali del traffico motorizzato, avvenuti in due domeniche dell’inverno 2001-2002, sulle concentrazioni di due inquinanti specifici per il traffico veicolare, il PM10 e il benzene.

    Metodologia: l’analisi è stata condotta in Lombardia considerando i dati ambientali delle tre zone critiche dove sono stati registrati i valori più elevati di inquinanti atmosferici e dove sono stati attuati i blocchi del traffico come misura d’emergenza (Milano, Como e Sempione. Tramite l’elaborazione di alcuni parametri metereologici, di grafici e di dati relativi l’andamento delle medie giornaliere e orarie degli inquinanti considerati è stata, quindi valutata l’efficacia dei blocchi stradali ai fini della diminuzione dell’inquinamento atmosferico.

    Risultati: i risultati ottenuti hanno evidenziato che le concentrazioni di inquinanti subiscono complessivamente un calo nelle ore di blocco del traffico, ma risalgono rapidamente a partire dalle ore successive la conclusione dei blocchi e non subiscono variazioni significative nei giorni successivi. I fattori metereologici (vento e pioggia intensa rivestono grande importanza nel condizionare la concentrazioni di PM10 e benzene.

    Conclusioni: i risultati confermano che i provvedimenti d’emergenza di limitazione del traffico non rappresentano una soluzione definitiva per ridurre complessivamente l’inquinamento atmosferico nelle aree urbane. Risulta, quindi, necessario effettuare

  20. Bismuth oxide aqueous colloidal nanoparticles inhibit Candida albicans growth and biofilm formation

    Directory of Open Access Journals (Sweden)

    Hernandez-Delgadillo R

    2013-04-01

    Full Text Available Rene Hernandez-Delgadillo,1 Donaji Velasco-Arias,3 Juan Jose Martinez-Sanmiguel,2 David Diaz,3 Inti Zumeta-Dube,3 Katiushka Arevalo-Niño,1 Claudio Cabral-Romero2 1Facultad de Ciencias Biológicas, Instituto de Biotecnologia, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, Mexico; 2Facultad de Odontología, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, México; 3Facultad de Quimica, Universidad Nacional Autonoma de Mexico, UNAM, Distrito Federal, México Abstract: Multiresistance among microorganisms to common antimicrobials has become one of the most significant concerns in modern medicine. Nanomaterials are a new alternative to successfully treat the multiresistant microorganisms. Nanostructured materials are used in many fields, including biological sciences and medicine. Recently, it was demonstrated that the bactericidal activity of zero-valent bismuth colloidal nanoparticles inhibited the growth of Streptococcus mutans; however the antimycotic potential of bismuth nanostructured derivatives has not yet been studied. The main objective of this investigation was to analyze the fungicidal activity of bismuth oxide nanoparticles against Candida albicans, and their antibiofilm capabilities. Our results showed that aqueous colloidal bismuth oxide nanoparticles displayed antimicrobial activity against C. albicans growth (reducing colony size by 85% and a complete inhibition of biofilm formation. These results are better than those obtained with chlorhexidine, nystatin, and terbinafine, the most effective oral antiseptic and commercial antifungal agents. In this work, we also compared the antimycotic activities of bulk bismuth oxide and bismuth nitrate, the precursor metallic salt. These results suggest that bismuth oxide colloidal nanoparticles could be a very interesting candidate as a fungicidal agent to be incorporated into an oral antiseptic. Additionally, we determined the minimum inhibitory concentration for the synthesized

  1. Implementing and Integrating a Clinically-Driven Electronic Medical Record (EMR for Radiation Oncology in a Large Medical Enterprise

    Directory of Open Access Journals (Sweden)

    John Paxton Kirkpatrick

    2013-04-01

    Full Text Available Purpose/Objective: While our department is heavily invested in computer-based treatment planning, we historically relied on paper-based charts for management of Radiation Oncology patients. In early 2009, we initiated the process of conversion to an electronic medical record (EMR eliminating the need for paper charts. Key goals included the ability to readily access information wherever and whenever needed, without compromising safety, treatment quality, confidentiality or productivity.Methodology: In February, 2009, we formed a multi-disciplinary team of Radiation Oncology physicians, nurses, therapists, administrators, physicists/dosimetrists, and information technology (IT specialists, along with staff from the Duke Health System IT department. The team identified all existing processes and associated information/reports, established the framework for the EMR system and generated, tested and implemented specific EMR processes.Results: Two broad classes of information were identified: information which must be readily accessed by anyone in the health system versus that used solely within the Radiation Oncology department. Examples of the former are consultation reports, weekly treatment check notes and treatment summaries; the latter includes treatment plans, daily therapy records and quality assurance reports. To manage the former, we utilized the enterprise-wide system , which required an intensive effort to design and implement procedures to export information from Radiation Oncology into that system. To manage "Radiation Oncology" data, we used our existing system (ARIA, Varian Medical Systems. The ability to access both systems simultaneously from a single workstation (WS was essential, requiring new WS and modified software. As of January, 2010, all new treatments were managed solely with an EMR. We find that an EMR makes information more widely accessible and does not compromise patient safety, treatment quality or confidentiality

  2. An Alpha spectrometer for measuring radon daughter individual activity concentration; Spettrometro Alfa per la misura delle concentrazioni individuali in attivita' della progenie del radon

    Energy Technology Data Exchange (ETDEWEB)

    Berico, M.; Formignani, M. [ENEA, Div. Protezione dell' Uomo e degli Ecosistemi, Centro Ricerche E. Clementel, Bologna (Italy); Mariotti, F. [Bologna Univ., Bologna (Italy). Dipt. di Fisica

    2001-07-01

    In the frame of the program of the Institute for Radiation Protection of ENEA, related to the evaluation of dose from radon and thoron progeny, an alpha spectrometer for the continuous air monitoring (CAM type) of radon and thoron has been realized. The constructive characteristics of the device are here presented together with energy and efficiency calibration. The device allows, by means of a screen type diffusion battery and a filter, to determinate the single radioactivity of each radionuclide of the progeny selecting them in relation to their diffusive behaviour (dichotomous particle size selection). The three-count filter method has been employed to measure the concentrations of {sup 218}Po, {sup 214}Pb and {sup 214}Bi in air. Radon and thoron effective doses using a dosimetric, instead of an epidemiologic approach, will be then evaluated. [Italian] Presso l'Istituto per la Radioprotezione, nell'ambito del programma di valutazione di dose da radon e' stato progettato e realizzato uno spettrometro alfa per il monitoraggio continuo in aria (CAM) della progenie del radon e del toron. Le caratteristiche costruttive dello strumento permettono, tramite l'utilizzo di batterie a diffusione a reti, di determinare l'attivita' individuale della progenie per diverse dimensioni granulometriche in particolare per la frazione attaccata e non al particolato amosferico con un taglio granulometrico di qualche nanometro. E' stato inoltre applicato un metodo spettrometrico a tre conteggi per il calcolo delle concentrazioni individuali della progenie del radon, {sup 218}Po, {sup 214}Pb and {sup 214}Bi, effettuando un conteggio alfa di {sup 218}Po e due conteggi alfa di {sup 214}Po. Tale informazione consentira' una valutazione della dose di radon utilizzando il modello dosimetrico in alternativa a quello epidemiologico.

  3. Laparoscopic Surgery for the Treatment of Ectopic Pregnancy

    Directory of Open Access Journals (Sweden)

    Hulusi B ZEYNELOGLU

    2005-09-01

    Full Text Available OBJECTIVE: To evaluate the outcomes of laparoscopic surgery for the treatment of ectopic pregnancy Design: 43 women with ectopic pregnancy who underwent laparoscopic surgery in our department between 1996 and 2005 were included in this study.\tSetting: Department of Obstetrics and Gynecology, School of Medicine, Baskent University, Ankara Patients: 43 women with ectopic pregnancy who underwent laparoscopic surgery Interventions: Laparoscopic surgery was performed the treatment of ectopic pregnancy Main Outcome Measures: Patients characteristics such as age, parity, gestational age at the time of diagnosis, symptoms, preoperative and postoperative serum _-hCG and hemoglobin levels, sonographic findings, type of laparoscopic surgery, blood transfusion, additional treatments, endometrial sampling and postoperative fertility status were recorded. The size and the location of myomas were obtained from the surgeon’s findings in the operative note. Preoperative and postoperative hemoglobin values, change in hemoglobin values, hemorrhage, blood transfusion, postoperative fewer, duration of operation and length of postoperative hospital stay were the main outcomes. RESULTS: Forty-three women with ectopic pregnancy who underwent laparoscopic surgery were included in this study. Patients were submitted usually with pelvic pain and abnormal vaginal bleeding. Adnexal mass and hemoperitoneum were seen by sonographic evaluation. Ampuller pregnancy was the most common. Most of patients had conservative surgery and 38% of patients underwent salpingectomy. 12 patient had blood transfusion and two ones underwent re-laparoscopy. After treatment 5 intrauterine pregnancies were occurred. Endometrial samplings usually defined as decidual en Aria stella reactions. Serum _-hCG levels were in normal range at the end of the month after the laparoscopy. CONCLUSION: In conclusion according to these findings, laparoscopic surgery remains the definitive and universal

  4. SEVERE CHRONIC ALLERGIC (AND RELATED DISEASES: A UNIFORM APPROACH — A MEDALL-GA2LEN-ARIA POSITION PAPER IN COLLABORATION WITH THE WHO COLLABORATING CENTER FOR ASTHMA AND RHINITIS (ENGLISH & RUSSIAN VARIANTS

    Directory of Open Access Journals (Sweden)

    J. Bousquet

    2011-01-01

    Full Text Available Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria, atopic dermatitis in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as co-morbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related diseases for clinical practice, research (including epidemiology, public health purposes, education and the discovery of novel therapies.Key words: IgE, allergy, severity, control, risk, asthma, rhinitis, rhinosinusitis, urticaria, atopic dermatitis.

  5. Síndrome de Cotard asociado a Trastorno Depresivo Mayor con síntomas catatónicos. Informe de caso / Cotard Syndrome Associated to Major Depressive Disorder with Catatonic Symptoms. Case report / Síndrome de Cotard associada ao transtorno depressivo maior com sintomas catatônicos. Relato de caso

    Directory of Open Access Journals (Sweden)

    Daniel Mauricio Torrado-Arenas

    2015-07-01

    Full Text Available Introduction: Catatonia is a neuropsychiatric syndrome with abnormal postures, mutism and stupor. Colombia has a prevalence of 11.4% of psychiatric patients. Objective: To discuss the clinical curse of a 34-year-old woman with major depressive disorder that presents to emergency department with nihilistic delirium and catatonic symptoms. Case presentation: A young woman with history of unipolar major depression with psychotic features was hospitalized nine months ago. She was medicated with a pharmacological treatment she did not remember. At admission, the patient had three days of bizarre behavior, mutism and negativism. Paraclinics and brain computer tomography did not report any abnormality or changes. Treatment began with benzodiazepine, which achieved full remission of catatonic symptoms. After this, she developed anhedonia, sadness and nihilistic delusions and was considered as a relapse of a previous depressive episode from nine months ago, associated with Cotard’s syndrome. Sertraline was added with gradual increase to 100mg and 5mg of olanzapine, getting a complete remission of psychotic and mood symptoms. Discussion: Affective disorders are most common cause of catatonia. There has already been a history of similar reports, but in few times these three entities were associated; this is the first case reported in Hospital Universitario de Santander, with informed consent. Conclusions: It is unusual for a depressed patient to present denial delusions and catatonic symptoms simultaneously; therefore this case is unusual and may contribute to literature. The catatonic symptoms make it difficult to explore other mental spheres, though they may be secondary to a medical condition, therefore, it is essential to dismiss organic pathologies and give initial treatment, so we can discover the underlying etiopsychopathology. [Torrado-Arenas DM, Santos-Gutiérrez KE, Ruiz-Higuera SM, Zabala-Arias LM, Niño-García JA. Síndrome de Cotard

  6. SU-C-202-03: A Tool for Automatic Calculation of Delivered Dose Variation for Off-Line Adaptive Therapy Using Cone Beam CT

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B; Lee, S; Chen, S; Zhou, J; Prado, K; D’Souza, W; Yi, B [University of Maryland School of Medicine, Baltimore, MD (United States)

    2016-06-15

    Purpose: Monitoring the delivered dose is an important task for the adaptive radiotherapy (ART) and for determining time to re-plan. A software tool which enables automatic delivered dose calculation using cone-beam CT (CBCT) has been developed and tested. Methods: The tool consists of four components: a CBCT Colleting Module (CCM), a Plan Registration Moduel (PRM), a Dose Calculation Module (DCM), and an Evaluation and Action Module (EAM). The CCM is triggered periodically (e.g. every 1:00 AM) to search for newly acquired CBCTs of patients of interest and then export the DICOM files of the images and related registrations defined in ARIA followed by triggering the PRM. The PRM imports the DICOM images and registrations, links the CBCTs to the related treatment plan of the patient in the planning system (RayStation V4.5, RaySearch, Stockholm, Sweden). A pre-determined CT-to-density table is automatically generated for dose calculation. Current version of the DCM uses a rigid registration which regards the treatment isocenter of the CBCT to be the isocenter of the treatment plan. Then it starts the dose calculation automatically. The AEM evaluates the plan using pre-determined plan evaluation parameters: PTV dose-volume metrics and critical organ doses. The tool has been tested for 10 patients. Results: Automatic plans are generated and saved in the order of the treatment dates of the Adaptive Planning module of the RayStation planning system, without any manual intervention. Once the CTV dose deviates more than 3%, both email and page alerts are sent to the physician and the physicist of the patient so that one can look the case closely. Conclusion: The tool is capable to perform automatic dose tracking and to alert clinicians when an action is needed. It is clinically useful for off-line adaptive therapy to catch any gross error. Practical way of determining alarming level for OAR is under development.

  7. Perspectives of Single-Wall Carbon Nano-tube Production in the Arc Discharge Process

    International Nuclear Information System (INIS)

    Krestinin, A.V.; Kiselev, N.A.; Raevskii, A.V; Ryabenko, A.G.; Zakharov, D.N.; Zvereva, G.I.

    2003-01-01

    Single-wall carbon nano tubes (SWNTs) promise wide applications in many technical fields. As a result purified SWNT material is sold now on the West market at more than 1000 dollars per 1 gram. Thus developing an effective technology for SWNTs production rises to a very important sintofene problem. The perspectives of three existing methods providing raw material in the technology of SWNT production have been analyzed. They are i) pulsed laser evaporation of graphite/metal composites, ii) evaporation of graphite electrodes with metal content in the are discharge process, and iii) catalytic decomposition of the mixture of CO and metal carbonyl catalyst precursor. The observed dynamites of SWNT market points to replacing the laser method of SWNTs production by the are process. The conclusion has been made that the technology based on the are process will be the major one for the fabrication of purified SWNTs at least for the next five years. A reliable estimation of a low price limit of SWNTs was derived from a comparison of two technologies based on the are discharge process: the first one is the production of SWNTs and the second one is the production of a fullerene mixture C 6 0 + C 7 0. The main conclusion was made that the price of purified SWNTs should always be more by 2-3 times the price of fullerene mixture. The parameters of a lab-scale technology for the production of purified SWNTs are listed. A large-scale application of the developed technology is expected to reduce the price of purified SWNTs by approximately ten times. The methods now employed for the characterization of products containing SWNTs are briefly observed. It is concluded that electron microscopy, thermogravimetric analysis, absorption and Raman spectroscopy, measurement of the specific surface aria, optical microscopy - each in separation is not enough for extensive characterization of a sample containing SWNTs, and all these methods should be used together. (author)

  8. Estudio del diagnóstico social en residencias para personas mayores asistidas en la Comunidad de Madrid: diseño de un instrumento de valoración y diagnóstico social

    Directory of Open Access Journals (Sweden)

    Silvia Patricia Cury

    2009-12-01

    Full Text Available El presente artículo es el resultado de la investigación, realizada por la autora, en el marco del Postgrado en Trabajo Social Comunitario, Gestión y Evaluación de Servicios Sociales, de la Escuela Universitaria de Trabajo Social, de la Universidad Complutense de Madrid, a lo largo del curso académico 2008-2009, que fue presentada como Memoria Final de Investigación, el día 7 de julio de 2009, bajo la dirección del Profesor Andrés Arias Astray. Esta Memoria se fundamenta en la importancia del diagnóstico como elemento decisivo de toda intervención social, y su finalidad consiste en realizar una aportación metodológica en este ámbito. En concreto, se realizó el estudio de la situación del diagnóstico social, en el ámbito de la atención a las personas mayores en Residencias asistidas de la Comunidad de Madrid y, en función de sus resultados, se elaboró el diseño de un Instrumento de Diagnóstico Social, para su aplicación en dicho ámbito. La elección del mismo responde a varios factores, que determinan su importancia y pertinencia, en el momento actual en las Residencias para personas mayores asistidas. Ente ellos, destaca la implantación de los Protocolos Asistenciales para Residencias de Mayores en la Comunidad de Madrid, y las necesidades de las trabajadoras sociales de integrarse en este proceso de protocolización, la actual situación demográfica en España y las previsiones al respecto, con un número creciente de personas mayores, los cambios sociológicos acaecidos en la institución familiar, y por lo tanto el desafío asistencial que estos factores suponen para la atención a las personas mayores en Centros Residenciales.

  9. Macrosomia Predictors in Infants Born to Cuban Mothers with Gestational Diabetes.

    Science.gov (United States)

    Cruz, Jeddú; Grandía, Raiden; Padilla, Liset; Rodríguez, Suilbert; Hernández García, Pilar; Lang Prieto, Jacinto; Márquez-Guillén, Antonio

    2015-07-01

    INTRODUCTION Fetal macrosomia is the most important complication in infants of women with diabetes, whether preconceptional or gestational. Its occurrence is related to certain maternal and fetal conditions and negatively affects maternal and perinatal outcomes. The definitive diagnosis is made at birth if a newborn weighs >4000 g. OBJECTIVE Identify which maternal and fetal conditions could be macrosomia predictors in infants born to Cuban mothers with gestational diabetes. METHODS A case-control study comprising 236 women with gestational diabetes who bore live infants (118 with macrosomia and 118 without) was conducted in the América Arias University Maternity Hospital, Havana, Cuba, during 2002-2012. The dependent variable was macrosomia (birth weight >4000 g). Independent maternal variables included body mass index at pregnancy onset, overweight or obesity at pregnancy onset, gestational age at diabetes diagnosis, pregnancy weight gain, glycemic control, triglycerides and cholesterol. Fetal variables examined included third-semester fetal abdominal circumference, estimated fetal weight at ≥28 weeks (absolute and percentilized by Campbell and Wilkin, and Usher and McLean curves). Chi square was used to compare continuous variables (proportions) and the student t test (X ± SD) for categorical variables, with significance threshold set at p gestational diabetes diagnosis, total fasting cholesterol and hypercholesterolemia. The highest OR for macrosomia were for maternal hypertriglyceridemia (OR 4.80, CI 2.34-9.84), third-trimester fetal abdominal circumference >75th percentile (OR 7.54, CI 4.04-14.06), and estimated fetal weight >90th percentile by Campbell and Wilkin curves (OR 4.75, CI 1.42-15.84) and by Usher and McLean curves (OR 8.81, CI 4.25-18.26). CONCLUSIONS Most variables assessed were predictors of macrosomia in infants of mothers with gestational diabetes. They should therefore be taken into account for future studies and for patient management

  10. TU-G-BRD-02: Automated Systematic Quality Assurance Program for Radiation Oncology Information System Upgrades

    International Nuclear Information System (INIS)

    Zhang, B; Yi, B; Eley, J; Mutaf, Y; Rahman, S; D’Souza, W

    2015-01-01

    Purpose: To: (1) describe an independent, automated, systematic software-based protocol for verifying clinical data accuracy/integrity for mitigation of data corruption/loss risks following radiation oncology information system (ROIS) upgrades; and (2) report on application of this approach in an academic/community practice environment. Methods: We propose a robust approach to perform quality assurance on the ROIS after an upgrade, targeting four data sources: (1) ROIS relational database; (2) ROIS DICOM interface; (3) ROIS treatment machine data configuration; and (4) ROIS-generated clinical reports. We investigated the database schema for differences between pre-/post-upgrade states. Paired DICOM data streams for the same object (such as RT-Plan/Treatment Record) were compared between pre-/post-upgrade states for data corruption. We examined machine configuration and related commissioning data files for changes and corruption. ROIS-generated treatment appointment and treatment parameter reports were compared to ensure patient encounter and treatment plan accuracy. This protocol was supplemented by an end-to-end clinical workflow test to verify essential ROI functionality and integrity of components interfaced during patient care chain of activities. We describe the implementation of this protocol during a Varian ARIA system upgrade at our clinic. Results: We verified 1,638 data tables with 2.4 billion data records. For 222 under-treatment patients, 605 DICOM RT plans and 13,480 DICOM treatment records retrieved from the ROIS DICOM interface were compared, with no differences in fractions, doses delivered, or treatment parameters. We identified 82 new data tables and 78 amended/deleted tables consistent with the upgrade. Reports for 5,073 patient encounters over a 2-week horizon were compared and were identical to those before the upgrade. Content in 12,237 xml machine files was compared, with no differences identified. Conclusion: An independent QA

  11. ‘Wie het die geheim verklap?’ – Seksuele identiteit in Johann Nell se plaasroman Sondag op ’n voëlplaas (2013

    Directory of Open Access Journals (Sweden)

    Joanita Erasmus-Alt

    2018-03-01

    Full Text Available ‘Who let out the secret?’ – Sexual identity in Johann Nell’s farm novel Sondag op ’n voëlplaas [Sunday on a bird farm] (2013. The statement of the narrator in Johann Nell’s farm novel Sondag op ’n voëlplaas (2013 about his self-quest amongst ‘wild, fierce and erect ostrich necks’ (pp. 244–245, alludes to his doubts about his sexual identity. The apparent latent homosexual is strengthened by the epigraph, a direct translation of an excerpt from Calaf’s aria ‘Nessun Dorma’ from Puccini’s opera Turandot. In the traditional Afrikaans farm novel, the narrator is usually a third-person (auctorial narrator. The use of a first-person narrator in Nell’s novel emphasises his deviation from the (stereotypical traits and attributes of the traditional farm novel. The subjectivity inherent to the firstperson narration (the I-as-protagonist implies that what is represented in this novel is the main character’s version of reality and his response to, especially, the farm as bastion of masculinity and traditional socio-political beliefs. Based on the above, this article takes as its point of departure the hypothetical assumption that the epigraph has an important part to play in the interpretation of the secret in that the implied or abstract author, by means of a parodying perspective, highlights a specific vision regarding the thematic significance. The epigraph not only reinforces the idea of a lack of identity and the idea that the ‘true’ identity could perhaps be a homosexual disposition, but also that it is simultaneously an etiological journey to the original opera libretto. In its turn, the libretto can be traced back to the Greek myth of Oedipus and the sphinx. By both discussing the intertexts and analysing the narrator’s language usage, his disposition and his tale of the (traumatised self, his sexual identity is scrutinised.

  12. SU-C-BRD-06: Sensitivity Study of An Automated System to Acquire and Analyze EPID Exit Dose Images

    Energy Technology Data Exchange (ETDEWEB)

    Olch, A; Zhuang, A [University of Southern California, Los Angeles, CA (United States)

    2015-06-15

    Purpose: The dosimetric consequences of errors in patient setup or beam delivery and anatomical changes are not readily known. A new product, PerFRACTION (Sun Nuclear Corporation), is designed to detect these errors by comparing the EPID exit dose image from each field of each fraction to those from baseline fraction images. This work investigates the sensitivity of PerFRACTION to detect the deviation of induced errors in a variety of realistic scenarios. Methods: Eight plans were created mimicking potential delivery or setup errors. The plans consisted of a nominal field and the field with an induced error. These were used to irradiate the EPID simulating multiple fractions with and without the error. Integrated EPID images were acquired in clinical mode and saved in ARIA. PerFRACTION automatically pulls the images into its database and performs the user defined comparison. In some cases, images were manually pushed to PerFRACTION. We varied the distance-to-agreement or dose tolerance until PerFRACTION showed failing pixels in the affected region and recorded the values. We induced errors of 1mm and greater in jaw, MLC, and couch position, 2 degree collimation rotation (patient yaw), and 0.5% to 1.5% in machine output. Both static and arc fields with the rails in or out were also acquired and compared. Results: PerFRACTION detected position errors of the jaws, MLC, and couch with an accuracy of better than 0.5 mm, and 0.2 degrees for collimator and gantry error. PerFRACTION detected a machine output error within 0.2% and detected the change in rail position. Conclusion: A new automated system for monitoring daily treatments for machine or patient variations from the first fraction using integrated EPID images was found to be sensitive enough to detect small positional, angular, and dosimetric errors within 0.5mm, 0.2 degrees, and 0.2%, respectively. Sun Nuclear Corporation has provided a software license for the product described.

  13. Gasto privado com saúde por classes de renda

    Directory of Open Access Journals (Sweden)

    KILSZTAJN SAMUEL

    2002-01-01

    Full Text Available OBJETIVO: O artigo analisa a participação do gasto privado com saúde das famílias no PIB e no total da renda familiar per capita e a distribuição do gasto privado com saúde das famílias por classes de renda. MÉTODOS: A pesquisa utilizou os microdados da Pesquisa Nacional por Amostra de Domicílios de 1998, com a divisão da população em quatro classes de renda familiar per capita e a distribuição dos gastos em planos de saúde, consultas médicas, consultas com outros profissionais de saúde, exames, medicamentos, artigos ortopédicos e aparelhos médicos, óculos e lentes, odontologia, hospitais, enfermagem domiciliar e outros gastos com saúde. RESULTADOS: Apenas 7,2% da população com renda familiar per capita até 1 salário mínimo em 1998 tinha direito a algum plano de saúde, e o gasto privado com saúde das famílias desta classe, que representava 52,5% da população, era em média de R$ 5,36 por pessoa. Para as pessoas com renda familiar per capita acima de 9 salários mínimos, os planos de saúde atingiam 83,2% da população e o gasto privado com saúde das famílias R$ 133,04. CONCLUSÕES: A implantação do Sistema Único de Saúde foi acompanhada pelo crescimento expressivo dos planos de saúde nos anos 90. Mesmo se todo o gasto público com saúde fosse destinado à população sem planos de saúde, ainda assim o gasto destas pessoas em 1998 só alcançaria R$ 352,62, ou seja, 43% do gasto com saúde das pessoas com planos, R$ 819,08.

  14. O debate dos economistas sobre a sustentabilidade: uma avaliação sob a ótica da análise do processo produtivo de Georgescu-Roegen

    Directory of Open Access Journals (Sweden)

    Charles C. Mueller

    2005-12-01

    Full Text Available O artigo avalia o debate que a economia do meio ambiente vem travando em torno do conceito de desenvolvimento sustentável, tendo por base contribuições de Nicholas Georgecu-Roegen. Este autor se notabilizou por ter trazido para a análise econômica o conceito de entropia, hoje peça fundamental da estrutura conceitual da economia ecológica. Entretanto, não é este o aspecto da obra de Georgecu-Roegen aqui focalizado. Ressaltam-se, ao invés, contribuições para a discussão derivadas de sua análise do processo produtivo. Procura-se mostrar, de forma especial, que a incorporação, pela economia do meio ambiente, da distinção, sugerida pelo autor, entre a categoria de capital natural de estoque e a de fundo de serviços ambientais básicos, forçaria as visões sobre a sustentabilidade a se confrontarem com aspectos fundamentais da inter-relação entre o sistema econômico e o meio ambiente, que hoje tendem a estar ocultos nas hipóteses simplificadoras da análise convencional da sustentabilidade.Based on contributions from Nicholas Georgescu-Roegen, the paper evaluates the debate in economics regarding the concept of sustainable development. This author is renowned for having introduced in economic analysis the concept of entropy, today an important building block of ecological economics. However, this is not the aspect focused here. We emphasize, instead, the contribution to the discussion that can be derived from his analysis of the production process. We point out, especially, that if the analysis of the interaction between the economic system and the environment incorporates the distinction suggested by the author, between the category of stocks of inputs of natural capital and that of its funds of basic environmental services, the sustainability debate would be forced to confront central aspects that tend to remain hidden by the simplifying assumptions of the conventional analyses of sustainability.

  15. [Trends in the urbanization process in Central America in the 1980's].

    Science.gov (United States)

    Lungo Ucles, M

    1990-01-01

    In the 1980s, urbanization in Central America was increasing compared to the three previous decades. By 1990, the urban population reached 42% in Guatemala, 44% in El Salvador, 43% in Honduras, 59% in Nicaragua, 53% in Costa Rica, and 54% in Panama. The urban population increased mostly in the largest cities, in contrast to Latin America, where secondary cities grew fastest. This trend was particularly true in Managua and San Salvador because of the military conflicts. The only exception was Honduras, where the second city underwent stronger growth. The urban population comprised 51.7% women and 48.3% men in Central America. The segregation and polarization of social classes was also increasing because of increased poverty and unemployment during the 1980s. This was partly caused by the increasing privatization of public services, decentralization, and the reinforcement of local governments, which all ensued from the structural readjustment programs of the International Monetary Fund. This neoliberal model of economic development in the short run resulted in increased poverty and unemployment for the urban populations. In 1982, the informal sector represented 29% of the total employment in Central America, and its share reached 40% in Managua and San Salvador. Urban unemployment increased from 2.2% in 1980 to 12% in 1988 in Guatemala; from 8.8% to 13.1% in Honduras; and from 10.4% to 20.8% in Panama. In the political arena, the process of democratization was underway, with civil presidents taking power and promoting privatization and deregulation of the economy. There was a close relationship between the urban social structure, the economy, and politics in the region. In Costa Rica, during the Arias administration between 1986 and 1990, a program was implemented creating 80,000 new homes, and in El Salvador there was an increasing demand to find a negotiated solution to the military conflict. These new political and economic perspectives could lead to genuine

  16. TU-G-BRD-02: Automated Systematic Quality Assurance Program for Radiation Oncology Information System Upgrades

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B; Yi, B; Eley, J; Mutaf, Y; Rahman, S; D’Souza, W [University of Maryland School of Medicine, Baltimore, MD (United States)

    2015-06-15

    Purpose: To: (1) describe an independent, automated, systematic software-based protocol for verifying clinical data accuracy/integrity for mitigation of data corruption/loss risks following radiation oncology information system (ROIS) upgrades; and (2) report on application of this approach in an academic/community practice environment. Methods: We propose a robust approach to perform quality assurance on the ROIS after an upgrade, targeting four data sources: (1) ROIS relational database; (2) ROIS DICOM interface; (3) ROIS treatment machine data configuration; and (4) ROIS-generated clinical reports. We investigated the database schema for differences between pre-/post-upgrade states. Paired DICOM data streams for the same object (such as RT-Plan/Treatment Record) were compared between pre-/post-upgrade states for data corruption. We examined machine configuration and related commissioning data files for changes and corruption. ROIS-generated treatment appointment and treatment parameter reports were compared to ensure patient encounter and treatment plan accuracy. This protocol was supplemented by an end-to-end clinical workflow test to verify essential ROI functionality and integrity of components interfaced during patient care chain of activities. We describe the implementation of this protocol during a Varian ARIA system upgrade at our clinic. Results: We verified 1,638 data tables with 2.4 billion data records. For 222 under-treatment patients, 605 DICOM RT plans and 13,480 DICOM treatment records retrieved from the ROIS DICOM interface were compared, with no differences in fractions, doses delivered, or treatment parameters. We identified 82 new data tables and 78 amended/deleted tables consistent with the upgrade. Reports for 5,073 patient encounters over a 2-week horizon were compared and were identical to those before the upgrade. Content in 12,237 xml machine files was compared, with no differences identified. Conclusion: An independent QA

  17. Use of a mobile social networking intervention for weight management: a mixed-methods study protocol.

    Science.gov (United States)

    Laranjo, Liliana; Lau, Annie Y S; Martin, Paige; Tong, Huong Ly; Coiera, Enrico

    2017-07-12

    Obesity and physical inactivity are major societal challenges and significant contributors to the global burden of disease and healthcare costs. Information and communication technologies are increasingly being used in interventions to promote behaviour change in diet and physical activity. In particular, social networking platforms seem promising for the delivery of weight control interventions.We intend to pilot test an intervention involving the use of a social networking mobile application and tracking devices ( Fitbit Flex 2 and Fitbit Aria scale) to promote the social comparison of weight and physical activity, in order to evaluate whether mechanisms of social influence lead to changes in those outcomes over the course of the study. Mixed-methods study involving semi-structured interviews and a pre-post quasi-experimental pilot with one arm, where healthy participants in different body mass index (BMI) categories, aged between 19 and 35 years old, will be subjected to a social networking intervention over a 6-month period. The primary outcome is the average difference in weight before and after the intervention. Secondary outcomes include BMI, number of steps per day, engagement with the intervention, social support and system usability. Semi-structured interviews will assess participants' expectations and perceptions regarding the intervention. Ethics approval was granted by Macquarie University's Human Research Ethics Committee for Medical Sciences on 3 November 2016 (ethics reference number 5201600716).The social network will be moderated by a researcher with clinical expertise, who will monitor and respond to concerns raised by participants. Monitoring will involve daily observation of measures collected by the fitness tracker and the wireless scale, as well as continuous supervision of forum interactions and posts. Additionally, a protocol is in place to monitor for participant misbehaviour and direct participants-in-need to appropriate sources of help

  18. Infección neonatal: comportamiento en una unidad de cuidados intensivos

    Directory of Open Access Journals (Sweden)

    Osmany Franco Argote

    2010-12-01

    Full Text Available INTRODUCCIÓN. El objetivo de este estudio fue caracterizar a los recién nacidos con sepsis atendidos en cuidados intensivos neonatales del Hospital «América Arias» en un período de 2 años. MÉTODOS. Se realizó una investigación cuantitativa, observacional, descriptiva y retrospectiva. El universo estuvo constituido por 214 neonatos. Las variables estudiadas fueron condiciones neonatales, manifestaciones clínicas de sepsis, gravedad, alteraciones humorales y antecedentes de procedimientos intervencionistas. Se hicieron combinaciones de algunas variables y se halló el valor de p para compararlas en neonatos con sepsis no grave o con sepsis grave. RESULTADOS. En el grupo estudiado la prematuridad, el bajo peso y el crecimiento intrauterino retardado alcanzaron cifras del 49,1 %, 42,1 % y 18,7 % respectivamente. El 72,9 % de los pacientes tuvo sepsis grave. Las manifestaciones clínicas más comunes fueron taquipnea (69,2 % y llenado capilar lento (57,9 %. La alteración humoral más frecuente fue la acidosis metabólica (63,6 % y el cateterismo umbilical fue el procedimiento intervencionista más frecuente (53,7 %. Predominaron las combinaciones de prematuridad y bajo peso (21,5 %, acidosis metabólica y neutrofilia (22 %, y asistencia respiratoria con cateterismo umbilical (21 % o epicutáneo (20,6 %. El valor de p fue de 0,001 entre pacientes con sepsis no grave y pacientes con sepsis grave en todas las combinaciones de intervencionismo, y no significativo en la combinación prematuro-bajo peso-crecimiento intrauterino retardado (CIUR. CONCLUSIONES. Hubo predominio de prematuridad, sepsis grave, taquipnea, cateterismo umbilical y acidosis metabólica. Las diferencias entre pacientes con sepsis no grave y con sepsis grave fueron significativas en todas las combinaciones de intervencionismo y de condición neonatal, pero no en la combinación prematuro-bajo peso-CIUR.

  19. Chemical and toxicological characterization of exhaust emissions from alternative fuels for urban public transport; Caratterizzazione chimica e tossicologica delle emissioni da carburanti alternativi per il trasporto pubblico nelle aree urbane

    Energy Technology Data Exchange (ETDEWEB)

    Turrio Baldassarri, L; Conti, R; Crebelli, B; Iamicelli, A L [Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, Roma (Italy); De Berardis, M [Dipartimento di Tecnologie e Salute, Istituto Superiore di Sanita, Roma (Italy); Gambino, A L; Iannaccone, S [Istituto dei Motori, CNR, Napoli (Italy)

    2008-07-01

    typhimurium, utilizzando diversi ceppi batterici. E stata inoltre valutata, tramite microscopia elettronica, la differenza nella distribuzione delle dimensioni del particolato emesso con i diversi combustibili. Infine, e stato discusso l'impatto sulla qualita dell'aria urbana e i potenziali effetti sulla salute che derivano dall'uso del gas naturale per il trasporto pubblico.

  20. ariação e parâmetros genéticos em dois bancos de germoplasma de Tabebuia heptaphilla (Velloso Toledo. Variation and genetic parameters in two germplasm banks of Tabebuia heptaphilla (Velloso Toledo.

    Directory of Open Access Journals (Sweden)

    Miguel Luiz Menezes FREITAS

    2008-06-01

    Full Text Available Os objetivos deste estudo foraminvestigar a variação genética e estimar parâmetrosgenéticos para caracteres de crescimento, forma esobrevivência aos 22 e 21 anos de idade em doistestes de progênies de Tabebuia heptaphylla,implantados na Estação Experimental de LuizAntônio, do Instituto Florestal de São Paulo.O teste I era composto por 19 progênies procedentesde Bauru-SP e o teste II por 15 progêniesprocedentes de Assis-SP. Diferenças significativasentre progênies foram observadas no teste I para oscaracteres forma e sobrevivência e no teste IIapenas para sobrevivência. A sobrevivência, emambos os ensaios, foi relativamente alta (> 77%,indicando que ambas as populações apresentaramboa adaptação às condições ambientais de LuizAntônio-SP. O coeficiente de variação genéticaentre progênies ( g CV foi, geralmente, baixo(£ 4,6%, sugerindo que a estratégia de amostragemadotada para conservar a variação genética daspopulações não foi eficiente, ou estas populaçõescontêm baixa variação genética. Os coeficientes deherdabilidade em nível de planta individual ( 2i h edentro de progênies ( 2d h foram igualmente baixos(máximo de 0,09. O coeficiente de herdabilidadeem nível de média de progênies ( 2m h foi alto paraa forma (mínimo 0,43 e sobrevivência (0,78,mostrando que o material testado em ambos osensaios possui potencial genético para responder àseleção natural. A estimativa do número statusantes da seleção no teste I e II indicou que os 570 e450 indivíduos, respectivamente, representam emmédia 39 e 31 árvores de uma população na qualnão existe parentesco nem endogamia. Após aseleção de seis plantas por progênie, o númerostatus foi estimado e as 114 e 90 árvoresselecionadas nos teste I e II, respectivamente,correspondem a 32 e 25 árvores não aparentadas enão endogâmicas. Os resultados em termos geraisindicaram baixa variação genética e pequenonúmero status retido em ambos os bancos degermoplasma.The aim of this study was to investigatethe genetic variation and to estimate geneticparameters for growth, form and survival traits at22 and 21 years of age in two progeny tests ofTabebuia heptaphylla, established in Luiz AntônioExperimental Station, belonging to the ForestryInstitute of the State of São Paulo. The test I wasestablished with 19 progenies from Bauruprovenance and the test II by 15 progenies fromAssis provenance. Significant differences amongprogenies were observed in the test I for form andsurvival and in test II for survival. The survival inboth tests was relatively high (> 77%, indicatingthat both populations present good adaptationto environmental condition of Luiz Antônio.The coefficient of genetic variation ( g CV wasgenerally low (£ 4.6%, suggesting that theadopted sampling strategy to conserve the geneticvariation of the populations was not efficientor both population have low genetic variation.The coefficients of heritability at individual plants( 2i h and within progenies levels ( 2d h were equallylow (maximum of 0.09. The coefficient ofheritability at progeny means level ( 2m h was highfor stem form (minimum 0.43 and survival (0.78,showing that both tested material have geneticpotential for selection. The estimative of the statusnumber before the selection in test I and II indicatedthat the 570 and 450 individuals, respectively,correspond to 39 and 31 not endogamic and relativetrees. After selection of six plants per progeny, thestatus number was reduced and the 114 and 90selected trees in test I and II, respectively, correspondto 32 and 25 trees non endogamic and withoutrelatedness. In general terms, the results indicatedthat low genetic variation and small status numberwas retained in both germoplasm banks.