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Sample records for solitude remoteness uncontrolled

  1. Space of solitude in culture

    Directory of Open Access Journals (Sweden)

    Agnieszka Małgorzata Kulig

    2014-04-01

    Full Text Available In my article I suggest looking at the phenomenon of solitude in culture not only as an opportunity to study an intimate and individual experience, to which numerous descriptions refer. I would rather consider whether possessing knowledge about this experience we acquire competencies regarding the culture in which this solitude has occurred. The discourse of melancholy, for which the space of solitude and confrontation with the ultimate has been the natural environment, supports me in describing the space of solitude in culture. For the purposes of reflection, I initiate my own definition of solitude as a space between life and death. That space allows the individual to feel the energy of life and the presence of death, even in such moments of human life (youth when the individual is not fully aware of their role in society, and is in the process of crystallizing their identity. In this case, solitude as a space between would be a state of suspension, which, however, prepares for active, independent life in the community. In this article, I refer to the postulate of the German culture researcher Thomas Macho in order to treat the experience of solitude as a context, an opportunity to practise techniques of culture, as well as to heterotopic space as defined by Michel Foucault.

  2. Le bord de la solitude

    Directory of Open Access Journals (Sweden)

    Jean-Paul Galibert

    2010-04-01

    Full Text Available La solitude a un bord, et non un seuil, parce que sinon, ce ne serait pas la solitude. Car le seuil a ceci de merveilleux qu’il sépare un dedans et un dehors, en sorte qu’il reste franchissable, et que l’on peut toujours sortir, et rentrer à sa guise. De ce fait, où que soient les autres, le seuil garantit donc que je pourrais les rejoindre, et me délasser, en changeant de lieu, des inconvénients croisés de l’intérieur et de l’extérieur. Dans le seuil, la métaphore implicite de la maison nous...

  3. Movement - uncontrolled or slow

    Science.gov (United States)

    Dystonia; Involuntary slow and twisting movements; Choreoathetosis; Leg and arm movements - uncontrollable; Arm and leg movements - uncontrollable; Slow involuntary movements of large muscle groups; Athetoid movements

  4. Better Off Alone: Daily Solitude Is Associated With Lower Negative Affect in More Conflictual Social Networks.

    Science.gov (United States)

    Birditt, Kira S; Manalel, Jasmine A; Sommers, Heidi; Luong, Gloria; Fingerman, Karen L

    2018-06-19

    Older adults are often considered at risk for social isolation. Little is known, however, about how often older adults lack social contact (in person, phone, electronic) throughout the day, the implications of lacking contact (i.e., solitude), and whether the effects of solitude vary by the broader social context. Participants were from the Daily Experiences and Well-being Study (DEWS) which included 313 older adults (aged 65+) who completed baseline interviews followed by 5-6 days of ecological momentary assessments approximately every 3 hr. Individuals reported having no social contact (i.e., solitude) on 11% of the occasions. Solitude predicted lower negative and positive affect on those occasions. The solitude-negative affect link varied by social network quality. Solitude predicted lower negative affect among individuals with more conflictual social networks but not among those with less conflictual networks. Overall, solitude may serve as an adaptive strategy for individuals embedded in demanding or irritating social contexts.

  5. The Solitude of Rural Teachers: Hebrew Teachers in Galilee Moshavot at the Beginning of the Twentieth Century

    Science.gov (United States)

    Seltenreich, Yair

    2015-01-01

    This article examines the need rural teachers felt for solitude and the place it took in their emotional world. Solitude was not seen by the teachers as a substitute for social life but, rather, considered as enriching it. Unlike loneliness, solitude was sought after and craved as it represented voluntary self-fulfilment in an environment that was…

  6. Why Classroom Climate Matters for Children High in Anxious Solitude: A Study of Differential Susceptibility

    Science.gov (United States)

    Hughes, Kathleen; Coplan, Robert J.

    2018-01-01

    The goal of the current study was to examine the complex links among anxious solitude, classroom climate, engagement, achievement, and gender. In particular, drawing upon the differential susceptibility hypothesis (Belsky, 1997), we investigated if children high in anxious solitude were particularly sensitive and responsive to the classroom…

  7. Embodied Humanism: Performative Argument for Natural Rights in "The Solitude of Self."

    Science.gov (United States)

    Stormer, Nathan

    1999-01-01

    Discusses how Elizabeth Cady Stanton's "The Solitude of Self" grounds rights in the material paradox of chance life events and the corporeal permanence of human isolation by enacting human solitude through what J. Campbell calls lyric tragedy. Reverses the ground for humanism from the disembodied rationalism of the Enlightenment to an…

  8. Why classroom climate matters for children high in anxious solitude: A study of differential susceptibility.

    Science.gov (United States)

    Hughes, Kathleen; Coplan, Robert J

    2018-03-01

    The goal of the current study was to examine the complex links among anxious solitude, classroom climate, engagement, achievement, and gender. In particular, drawing upon the differential susceptibility hypothesis (Belsky, 1997), we investigated if children high in anxious solitude were particularly sensitive and responsive to the classroom environment. Participants were N = 712 children in Grade 3, drawn from the National Institute of Child and Human Development (NICHD) Study of Early Child Care and Youth Development data set. Classroom climate and engagement were assessed using the Classroom Observation Scale (NICHD, 1998). Teachers completed the Teacher Report Form (Achenbach, 1991) as a measure of anxious solitude and the Academic Rating Scale (NICHD, 2010) as a measure of achievement. Hypothesized associations among variables were tested by way of a moderated-mediation model. Among the results, engagement was found to mediate the relation between classroom climate and achievement. In addition, anxious solitude and gender were found to moderate the relation between classroom climate and engagement. Support for the differential susceptibility hypothesis was found, suggesting that children high in anxious solitude may be more reactive (both positively and negatively) to elements of the classroom environment. In addition, gender differences were observed, indicating that boys may be more responsive to the classroom environment as compared with girls. Implications for future research and educational policies are discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  9. Republic of Noise: The Loss of Solitude in Schools and Culture

    Science.gov (United States)

    Senechal, Diana

    2011-01-01

    In "Republic of Noise," Diana Senechal confronts a culture that has come to depend on instant updates and communication at the expense of solitude. Where once it was common wisdom that the chatter of the present, about the present, could not always grasp the present, today we treat "real time" as though it were the only real time. Schools…

  10. The Necessity of the Literary Tradition: Gabriel Garcia Marquez's "One-Hundred Years of Solitude."

    Science.gov (United States)

    Jupp, James C.

    2000-01-01

    Argues that literature from other countries, taught as multicultural literature, must be taught in the context of its own literary tradition in order to provide high-quality academic instruction. Offers an example with Gabriel Garcia Marquez's "One-Hundred Years of Solitude" to show how teaching multicultural literature can live up to…

  11. The flight of uncontrolled rockets

    CERN Document Server

    Gantmakher, F R; Dryden, H L

    1964-01-01

    International Series of Monographs on Aeronautics and Astronautics, Division VII, Volume 5: The Flight of Uncontrolled Rockets focuses on external ballistics of uncontrolled rockets. The book first discusses the equations of motion of rockets. The rocket as a system of changing composition; application of solidification principle to rockets; rotational motion of rockets; and equations of motion of the center of mass of rockets are described. The text looks at the calculation of trajectory of rockets and the fundamentals of rocket dispersion. The selection further focuses on the dispersion of f

  12. Solitude and modernity: Some reflections on Annette von Droste-Hülshoff’s poetry

    Directory of Open Access Journals (Sweden)

    Alessandro Alba

    2014-06-01

    Full Text Available Solitude and modernity: Some reflections on Annette von Droste-Hülshoff’s poetry. The text aims to an analysis of Droste’s poetry in consideration of the condition of the modern poet, who reflects upon himself’s loneliness. Far from being an individual, autobiographical condition, it is the basis for a consideration about general human’s condition, his social alienation which has made him/her incapable of feeling nature.

  13. Magic Realism in Gabriel Garcia Marquez’s One Hundred Years of Solitude

    OpenAIRE

    B.J Geetha

    2010-01-01

    In his One Hundred Years of Solitude Gabriel Garcia Marquez through the arsenal of magicrealism, deals with war, suffering, and death in the mid-1960 of Colombia which hadwitnessed two hundred thousand politically motivated deaths. The purpose behind portrayingthe politics of the region is to comment on how the nature of Latin American politics is towardsabsurdity, denial, and never-ending repetitions of tragedy. His magical flair is to mergefantastic with reality by introducing to the reader...

  14. Perceptual verbs in gabriel garcía márquez's novel "one hundred years of solitude"

    OpenAIRE

    Kriščiūnaitė, Agnė

    2017-01-01

    Perceptual Verbs in Gabriel García Márquez's Novel "One Hundred Years of Solitude" This BA thesis presents an analysis of the perception Spanish and Lithuanian verbs (further – PV) in Gabriel García Márquez’s novel One Hundred Years of Solitude and its translation to Lithuanian by E. Treinienė and N. A. Petrauskienė released by the title of Šimtas metų vienatvės in 2006. According to the analysis of the five senses of perception verbs are classified into five semantic cate...

  15. Masked Uncontrolled Hypertension in CKD.

    Science.gov (United States)

    Agarwal, Rajiv; Pappas, Maria K; Sinha, Arjun D

    2016-03-01

    Masked uncontrolled hypertension (MUCH) is diagnosed in patients treated for hypertension who are normotensive in the clinic but hypertensive outside. In this study of 333 veterans with CKD, we prospectively evaluated the prevalence of MUCH as determined by ambulatory BP monitoring using three definitions of hypertension (daytime hypertension ≥135/85 mmHg; either nighttime hypertension ≥120/70 mmHg or daytime hypertension; and 24-hour hypertension ≥130/80 mmHg) or by home BP monitoring (hypertension ≥135/85 mmHg). The prevalence of MUCH was 26.7% by daytime ambulatory BP, 32.8% by 24-hour ambulatory BP, 56.1% by daytime or night-time ambulatory BP, and 50.8% by home BP. To assess the reproducibility of the diagnosis, we repeated these measurements after 4 weeks. Agreement in MUCH diagnosis by ambulatory BP was 75-78% (κ coefficient for agreement, 0.44-0.51), depending on the definition used. In contrast, home BP showed an agreement of only 63% and a κ coefficient of 0.25. Prevalence of MUCH increased with increasing clinic systolic BP: 2% in the 90-110 mmHg group, 17% in the 110-119 mmHg group, 34% in the 120-129 mmHg group, and 66% in the 130-139 mmHg group. Clinic BP was a good determinant of MUCH (receiver operating characteristic area under the curve 0.82; 95% confidence interval 0.76-0.87). In diagnosing MUCH, home BP was not different from clinic BP. In conclusion, among people with CKD, MUCH is common and reproducible, and should be suspected when clinic BP is in the prehypertensive range. Confirmation of MUCH diagnosis should rely on ambulatory BP monitoring. Copyright © 2016 by the American Society of Nephrology.

  16. An Exploratory Study of the Restorative Benefits of Hiking in Wilderness Solitude and Its Relationship to Job Satisfaction

    Science.gov (United States)

    Ellison, Mark Andrew

    2010-01-01

    The purpose of this exploratory research was to examine the relationship between the restorative benefits of hiking in wilderness solitude (RBHWS) and job satisfaction. This research is a jumping off point, intended to guide future research on the RBHWS, and the practical utilization of this in human resource development. This research sought to…

  17. One hundred years of solitude, accumulation and violence: A comparative historical analysis of the Sierra Nevada of Santa Marta Valley

    NARCIS (Netherlands)

    M.E. Bedoya Arias (María Eugenia )

    2013-01-01

    textabstractThis is an analysis of two moments in the Colombian history within a century of difference, where isolation, accumulation and violence interact in a region brought into the worlds’ imaginary by the Colombian novelist Gabriel García Márquez in One Hundred years of Solitude. A valley

  18. Old Age, Widows, and Rural Solitude in the Eighteenth Century Central-Southern Spain

    Directory of Open Access Journals (Sweden)

    Francisco GARCÍA GONZÁLEZ

    2016-12-01

    Full Text Available Current research about old age during the Ancient Regime in Spain is insufficient. And the same is the case with women, despite the large number of studies about gender and family history in the past decades. Taking, as a starting point, the analysis of widow women which became heads of households, this paper aims to know which specific characteristics had those households during their old age, composition, size, typology and the tendency to solitude; which activities and livelihood they had, paying attention to those differences as an expression of inequality; and which mechanisms and social reproduction strategies they followed to deal with the effects of aging. This paper is geografically focused in a wide rural area of central-southern Spain and aims to review the assumption that single and widow women in preindustrial age had subordinted lives. 

  19. Political Ecology in Gabriel Garcia Marquez's One Hundred Years of Solitude

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    Eman Mohammed ElSherief

    2016-04-01

    Full Text Available The roots of ecology prolong profoundly within earlier phases of history, when the naturalistic fabric was first evinced.  Bringing out his On the Origin of Species in 1859, Darwin not merely engendered a biological culmination but also heralded the revolutionary critical canon of naturalism that was virtually a stone thrown in the vast stagnant lake of traditional literature. Via the naturalistic lens, the whole bulk of man’s behavioral attributes are being expounded in terms of milieu and heredity. The mid-1990s witnessed the publication of The Environmental Imagination by Lawrence Buell in 1995, and The Ecocriticism Reader edited by Cheryll Gloffelty and Harold Fromm in 1996, which palpably underpinned ecocriticism as revolving around the inextricable liaison between literature and the physical environment. The political ecology term was coined to further scrutinize relations among people that pertain to nature. The present paper is an endeavor to pursue the ecological tenor of Gabriel Garcia Marquez’s landmark novel, One Hundred Years of Solitude, and how it was admirably exploited to address precarious postcolonial issues. Keywords: Political ecology, Marquez, naturalism, ecocriticism, post-colonialism.

  20. The poorly explored impact of uncontrolled asthma

    DEFF Research Database (Denmark)

    O'Byrne, Paul M; Pedersen, Søren; Schatz, Michael

    2013-01-01

    The goal of asthma management is to achieve disease control; however, despite the availability of effective and safe medications, for many patients asthma remains uncontrolled. One reason for this is the fear of long-term side effects from the regular use of inhaled corticosteroids (ICSs). Adverse...... effects of poorly controlled asthma (for example, obesity, pneumonia, and risks to the fetus) can be perceived as side effects of ICSs. Poorly controlled asthma adversely affects children's cardiovascular fitness, while children with well-controlled asthma perform at the same level as their peers....... Children with uncontrolled asthma also have a higher frequency of obesity than children with controlled asthma. Stress can affect asthma control, and children with poorly controlled asthma are more likely to have learning disabilities compared with those with good control. In adults, focused attention...

  1. Acute compartment syndrome caused by uncontrolled hypothyroidism.

    Science.gov (United States)

    Modi, Anar; Amin, Hari; Salzman, Matthew; Morgan, Farah

    2017-06-01

    Acute compartment syndrome is increased tissue pressure exceeding perfusion pressure in a closed compartment resulting in nerve and muscle ischemia. Common precipitating causes are crush injuries, burns, substance abuse, osseous or vascular limb trauma. This is a case of 42year old female with history of hypothyroidism who presented to emergency room with acute onset of severe pain and swelling in right lower extremity. Physical examination was concerning for acute compartment syndrome of right leg which was confirmed by demonstration of elevated compartmental pressures. No precipitating causes were readily identified. Further laboratory testing revealed uncontrolled hypothyroidism. Management included emergent fasciotomy and initiating thyroid hormone replacement. This case represents a rare association between acute compartment syndrome and uncontrolled hypothyroidism. We also discuss the pathogenesis of compartment syndrome in hypothyroid patients and emphasize the importance of evaluating for less common causes, particularly in setting of non-traumatic compartment syndrome. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Endo-Perio Lesion and Uncontrolled Diabetes

    OpenAIRE

    Dhoum, Sara; Laslami, Kaoutar; Rouggani, Fatimazahraa; El Ouazzani, Amal; Jabri, Mouna

    2018-01-01

    This work is to discuss the management of an endo-perio lesion, which represents a challenge to clinicians when it comes to diagnosis and prognosis of the involved teeth and especially with an altered general condition. A 50-year-old female patient with uncontrolled diabetes type 2 is suffering from a purulent discharge coming from the upper right canine. Endodontic and periodontal treatments were realized with 36 months radiological and clinical follow-up with the collaboration of her intern...

  3. Endo-Perio Lesion and Uncontrolled Diabetes.

    Science.gov (United States)

    Dhoum, Sara; Laslami, Kaoutar; Rouggani, Fatimazahraa; El Ouazzani, Amal; Jabri, Mouna

    2018-01-01

    This work is to discuss the management of an endo-perio lesion, which represents a challenge to clinicians when it comes to diagnosis and prognosis of the involved teeth and especially with an altered general condition. A 50-year-old female patient with uncontrolled diabetes type 2 is suffering from a purulent discharge coming from the upper right canine. Endodontic and periodontal treatments were realized with 36 months radiological and clinical follow-up with the collaboration of her internist doctor.

  4. Cien años de soledad, de Gabriel García Márquez. La solitude ontologique d'un monde sans transcendance.

    OpenAIRE

    Gladieu , Marie-Madeleine

    2010-01-01

    Gabriel García Márquez dans son roman Cent ans de solitude présente toute une lignée de personnages qui déambulent au fil de l'histoire pouvant laisser croire dans une premier temps en une apparente chaîne de solidarité qui se délite sous le poids de la mémoire et des événements historiques et ne laissant aucune transcendance qui pourrait apporter une consolation à la solitude absolue de Macondo.

  5. The Reliability of the Narrator in Salman Rushdie's Midnight's Children and Gabriel Garcia Marguez's One Hundred Years of Solitude

    OpenAIRE

    McFadden, Ronan

    2008-01-01

    In the simultaneously fantastic and earthly world of the magical-realist novel, where telepathic powers are discovered through the clearing of snot, or where girls ascend to heaven while hanging out the laundry, how do the narrators of Gabriel García Márquez’s One Hundred Years of Solitude and Salman Rushdie’s Midnight’s Children attempt to convince the reader of the narratives’ reliability? Can the reader really rely on the truth of such fantastic narratives? If not, what precisely are Garcí...

  6. Preference for Solitude, Social Isolation, Suicidal Ideation, and Self-Harm in Adolescents.

    Science.gov (United States)

    Endo, Kaori; Ando, Shuntaro; Shimodera, Shinji; Yamasaki, Syudo; Usami, Satoshi; Okazaki, Yuji; Sasaki, Tsukasa; Richards, Marcus; Hatch, Stephani; Nishida, Atsushi

    2017-08-01

    Social isolation is associated with suicidal ideation (SI) and self-harm (SH) among adolescents. However, the association between preference for solitude (PfS), SI, and SH is unknown. The prevalence of adolescents who have both of PfS and social isolation and the risks for SI and SH among them are also unknown. Information on PfS, social isolation, SI, and SH was collected in a large-scale school-based survey on adolescents, using a self-report questionnaire. Associations between PfS, SI, and SH were examined by logistic regression analysis. The interactions between PfS and social isolation on SI and SH were also investigated. The odds of SI and SH were examined for groups defined by presence of PfS and social isolation. Responses from 17,437 students (89.3% of relevant classes) were available. After adjusting for demographic characteristics and social isolation, PfS was associated with increased odds of SI (odds ratio [OR] = 3.1) and SH (OR = 1.9). There was no interaction between PfS and social isolation on SI and SH. After adjusting for demographic characteristics, the odds for SI (OR = 8.6) and SH (OR = 3.8) were highest among adolescents with both PfS and social isolation (8.4% of all respondents). PfS was associated with increased odds of SI and SH in adolescents. No interaction effect between PfS and social isolation on SI and SH was found, but adolescents with PfS and social isolation had the highest risk for SI and SH. Parents and professionals should pay attention to suicide risk in adolescents with PfS. Copyright © 2017 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  7. 'The quicksand of forgetfulness': semantic dementia in One hundred years of solitude.

    Science.gov (United States)

    Rascovsky, Katya; Growdon, Matthew E; Pardo, Isela R; Grossman, Scott; Miller, Bruce L

    2009-09-01

    This multidisciplinary article compares the pattern of memory loss described in Gabriel García Márquez's One Hundred Years of Solitude to that exhibited by patients with semantic dementia (SD). In his renowned novel, García Márquez depicts the plight of Macondo, a town struck by the dreaded insomnia plague. The most devastating symptom of the plague is not the impossibility of sleep, but rather the loss of 'the name and notion of things'. In an effort to combat this insidious loss of knowledge, the protagonist, José Arcadio Buendía, 'marked everything with its name: table, chair, clock, door, wall, bed, pan'. 'Studying the infinite possibilities of a loss of memory, he realized that the day might come when things would be recognized by their inscriptions but that no one would remember their use'. The cognitive impairments experienced by Macondo's inhabitants are remarkably similar to those observed in SD, a clinical syndrome characterized by a progressive breakdown of conceptual knowledge (semantic memory) in the context of relatively preserved day-to-day (episodic) memory. First recognized in 1975, it is now considered one of the main variants of frontotemporal lobar degeneration. Writing within the realm of magical realism and investigating the power of language as a form of communication, García Márquez provides beautiful descriptions of the loss of 'the name and notion of things' typical of the syndrome. He further speculates on ways to cope with this dissolution of meaning, ranging from 'the spell of an imaginary reality' to José Arcadio's 'memory machine', strategies that resonate with attempts by semantic dementia patients to cope with their disease. Remarkably, García Márquez created a striking literary depiction of collective semantic dementia before the syndrome was recognized in neurology. The novel also provides an inspiring and human account of one town's fight against 'the quicksand of forgetfulness'.

  8. Endo-Perio Lesion and Uncontrolled Diabetes

    Directory of Open Access Journals (Sweden)

    Sara Dhoum

    2018-01-01

    Full Text Available This work is to discuss the management of an endo-perio lesion, which represents a challenge to clinicians when it comes to diagnosis and prognosis of the involved teeth and especially with an altered general condition. A 50-year-old female patient with uncontrolled diabetes type 2 is suffering from a purulent discharge coming from the upper right canine. Endodontic and periodontal treatments were realized with 36 months radiological and clinical follow-up with the collaboration of her internist doctor.

  9. ‘The quicksand of forgetfulness’: semantic dementia in One Hundred Years of Solitude

    Science.gov (United States)

    Growdon, Matthew E.; Pardo, Isela R.; Grossman, Scott; Miller, Bruce L.

    2009-01-01

    This multidisciplinary article compares the pattern of memory loss described in Gabriel García Márquez's One Hundred Years of Solitude to that exhibited by patients with semantic dementia (SD). In his renowned novel, García Márquez depicts the plight of Macondo, a town struck by the dreaded insomnia plague. The most devastating symptom of the plague is not the impossibility of sleep, but rather the loss of ‘the name and notion of things’. In an effort to combat this insidious loss of knowledge, the protagonist, José Arcadio Buendía, ‘marked everything with its name: table, chair, clock, door, wall, bed, pan’. ‘Studying the infinite possibilities of a loss of memory, he realized that the day might come when things would be recognized by their inscriptions but that no one would remember their use’. The cognitive impairments experienced by Macondo's inhabitants are remarkably similar to those observed in SD, a clinical syndrome characterized by a progressive breakdown of conceptual knowledge (semantic memory) in the context of relatively preserved day-to-day (episodic) memory. First recognized in 1975, it is now considered one of the main variants of frontotemporal lobar degeneration. Writing within the realm of magical realism and investigating the power of language as a form of communication, García Márquez provides beautiful descriptions of the loss of ‘the name and notion of things’ typical of the syndrome. He further speculates on ways to cope with this dissolution of meaning, ranging from ‘the spell of an imaginary reality’ to José Arcadio's ‘memory machine’, strategies that resonate with attempts by semantic dementia patients to cope with their disease. Remarkably, García Márquez created a striking literary depiction of collective semantic dementia before the syndrome was recognized in neurology. The novel also provides an inspiring and human account of one town's fight against ‘the quicksand of forgetfulness’. PMID

  10. Cooperative Testing of Uncontrollable Timed Systems

    DEFF Research Database (Denmark)

    David, Alexandre; Larsen, Kim Guldstrand; Li, Shuhao

    2008-01-01

    the SUT against the test purpose as long as the SUT reacts to our moves in a cooperative style. We present an operational framework of cooperative winning strategy generation, test case derivation and execution. The test method is proved to be sound and complete. Preliminary experimental results indicate......Abstract. This paper deals with targeted testing of timed systems with uncontrollable behavior. The testing activity is viewed as a game between the tester and the system under test (SUT) towards a given test purpose. The SUT is modeled as Timed Game Automaton and the test purpose is specified...... in Timed CTL formula. We can employ a timed game solver UPPAAL-TIGA to check if the test purpose is ture w.r.t. the model, and if yes, to generate a winning strategy and use it for black-box conformance testing. Specifically, we show that in case the checking yields a negative result, we can still test...

  11. The selective external carotid arterial embolization treatment of uncontrollable epistaxis

    International Nuclear Information System (INIS)

    Yao Qunli; Liu Yizhi; Ni Caifang

    2004-01-01

    Objective: To evaluate the selective external carotid arterial embolization of uncontrollable epistaxis. Methods: 27 procedures of super-selective external carotid arterial embolization were performed with absorbable gelfoam by using Seldinger's method in 26 cases with uncontrollable epistaxis. Results: 27 procedures of super-selective intra-arterial embolization of uncontrollable epistaxis were all successful without any serious complication. Conclusions: Selective external carotid arterial embolization is safe, effective and successful in the treatment of severe epistaxis. (authors)

  12. Processes on Uncontrolled Aerodromes and Safety Indicators - Part II

    Directory of Open Access Journals (Sweden)

    Vladimír Plos

    2014-01-01

    Full Text Available This article follows on the Part I, where the basic processes on uncontrolled aerodromes were introduced. The uncontrolled aerodromes face with the growing traffic and from that result the higher workload on AFIS officer. This means a higher potential for dangerous situations.The article describes some models of sub-processes and creates several safety indicators related to the operation at uncontrolled aerodromes. Thanks to monitoring and evaluation of safety indicators can be adopted targeted safety measures and thus increase safety on small uncontrolled aerodromes.

  13. Valences temporal tuning fork in novel One Hundred Years of Solitude by Gabriel García Márquez

    Directory of Open Access Journals (Sweden)

    Victoria BARAGA

    2013-01-01

    Full Text Available Class time is experiencing a particularly wide spread in different spheres of human manifestation: in science and art, religion and everyday life. During World Literature the time becomes subject to interest. Colombian writer Gabriel García Márquez in his creation, but especially in the novel One Hundred Years of Solitude, with great talent show time category. In the present investigation, based on the content quality of time and in the figurative image of the movement, we deduced the most representative forms of temporal in garciamarquezian novel. We disclose specifics forms of macondiene time: Time of sacred history, time of eternal return, historical time and Apocalyptic time. Originality of macondian time consists of temporal relationship between these forms, the magic of virtualization game and their updates. And while macondian prodigious time impresses just by strength revealing of the imaginary area.

  14. On the Controllability Principles and the Construction of Uncontrollability

    DEFF Research Database (Denmark)

    Friis, Ivar; Gevoll, Linn; Hansen, Allan

    A key challenge when it comes to coping with the controllability principle is to understand why and how uncontrollability occurs. In this paper we draw on the Actor-Network Theory to provide more insight to why and how uncontrollability emerges in organizations. By means of an in-depth case study...... of a wide range of heterogeneous actors that connects in multiple ways and that in combination forms a complex network of relations which affect delivery time performance. Our study adds to research on the controllability principle. Whereas prior research has characterized uncontrollability as determined...... uncontrollability more specifically is about. Thus, our study adds to as well as elaborates on prior research. We illustrate how uncontrollability arise in the intersects of several heterogeneous elements such as the product information systems, quality management, incentive systems, outsourcing and customers. We...

  15. UNCONTROLLED PHOTOMULTIPLIER CURRENT IN PHOTOEMISSION ANALYSIS

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    K. A. Viazava

    2016-01-01

    Full Text Available The dependence of photon energy from energy of photoelectron is base of photoemission radiation analysis. In such photoemission measurements except current of photocathode is always exist a reverse current from the collector of electrons to the photocathode in two-electrode sensors. There are various ways of reverse and uncontrolled current eliminating or reducing their influence. The constructive method is based on creating an electron-optical system of photoelectronic device, which would be a photoelectron energy analyzer. The second method – technological. However, it requires the manufacture of the photocathode and the dynode system in different vacuum chamber with subsequent connection to a single device in vacuum environment without exposure to the atmosphere. The purpose of this article is to determinate the effect of photoemission from photocathode chamber and the first dynode of photomultiplier on energy distribution of the photoelectrons from photocathode. To solve this problem authors obtained calibration curves for measuring pyrometer module ПИФ 4/2 with ФЭУ-114 as a sensor at supply voltage 1350 V and different decelerating voltages. The effect of illumination on the value of modulation coefficient on temperature k(T and wavelength k(λ is shown. In temperature measurements, this effect is evident in fact that at temperatures below 1400 K linear dependence ln k – T-1 is broken. Still this linear dependence is a necessary consequence of the fact that the measured temperature is color temperature. However, this calibration curve can be used to measure low temperature if the target measurements condition and calibration conditions are identical. In wavelength calibration, curve k(λ at λ > 760 nm is two-valued, that doesn’t allow to identify monochromatic radiation by this method and bring in errors in temperature measurements. 

  16. Rewriting rural community and dictatorial history through magical realism in Márquez’s One Hundred Years of Solitude

    Directory of Open Access Journals (Sweden)

    Abdullah Abu Shahid

    2015-05-01

    Full Text Available Márquez was greatly influenced by his grandmother’s story-telling ability, and was highly indebted to the socio-political history of Latin America, particularly Colombia. In One Hundred Years of Solitude, he wants to reconstruct the lost world of childhood by using magical realism which gives expression to the world-view of a rural people who live in isolation from modern world. By retelling the official history from the perspective of the oppressed, he reveals the fact that history is never factual and impartial but serves the interest of those who write it. Through the banana company massacre and the subsequent hide and seek over the number of dead workers, Márquez exposes the way official history becomes fabricated and distorted by authorities, and fails to provide the original occurrences. He was disgusted with the political violence and civil wars which had distraught people; he was also against capitalism, scientific and technological inventions, and so-called modernization, which are the means through which foreign culture brings corruption and brutality, dominates, exploits and oppresses the natives, and threatens the native culture and identity. By employing magical realism, he was able to recreate Colombian history to protest against the way capitalism dominated the socio-political and economic structure of the region.

  17. Association of Controlled and Uncontrolled Hypertension With Workplace Productivity.

    Science.gov (United States)

    Unmuessig, Victoria; Fishman, Paul A; Vrijhoef, Hubertus J M; Elissen, Arianne M J; Grossman, David C

    2016-03-01

    The authors estimated the lost productive time (LPT) due to absenteeism and presenteeism among employees at the Group Health Cooperative with controlled and uncontrolled hypertension compared with normotensive patients. The patients responded to a survey inquiring about health behaviors with links to their medical record to identify diagnoses, blood pressure measurement, and prescription drug dispenses. Individuals with controlled hypertension were more likely to report any LPT relative to individuals with uncontrolled hypertension (40.6% vs 32.6%, Pabsenteeism compared with normotensive individuals (1.04 vs 0.59 hours; P=.001). Individuals with uncontrolled hypertension were more likely to report LPT due to absenteeism compared with individuals with controlled hypertension (1.35 vs 0.72 hours; P=.001). There were no significant differences between individuals with hypertension whose blood pressure was controlled and normotensive individuals with respect to the likelihood of reporting any LPT or in the amounts of absenteeism and presenteeism. © 2015 Wiley Periodicals, Inc.

  18. Üksildus küberruumis: autori individuaalsus ja teksti autonoomia. Solitude in Cyberspace: the Individuality of an Author and the Autonomy of a Text

    Directory of Open Access Journals (Sweden)

    Virve Sarapik

    2012-06-01

    Full Text Available The keywords in analyses of digital literature and cybertexts (literature that has been created by and is read on a computer mostly derive from the vocabulary of increasing collectivism: shared authorship, readerviewer interaction, their active participation in creating text etc. However, this article focuses on the opposite phenomenon: the essence of individualism in the process of digital text creation, that is, solitude. At the same time, the paradoxes related to collectivism and solitude are also addressed. In this article, solitude is regarded as a technical term, indicating the number of different agents in a creative process. This primarily means: whether the text can be associated with one author and his intention, or whether authorship is distributed between several people who have participated in the creation of the text, as well as if and how much texts presume activity on the part of the reader. We can claim that when writers write their texts they are usually on their own. A text is born in the writer’s head and he or she needs some kind of form to present it. When the form of literature was mostly what was recorded on paper, we could say that the author formalised his text in solitude – writing alone on pieces of paper. Only after the manuscript was handed in were other participants added, such as the editor, designer and printer, who took part in the completion process of the literary work. However, when the end result of production is not a printed book, but a cyber- or hypertext, we can assume that these relationships change significantly in the case of digital literature. In addition to the author of the text, cybertexts and hypertexts need active co-authors: programmers, designers etc. Creating a cybertext is, therefore, basically a collective act (although there are of course exceptions. The author of a cybertext is no longer the only and unique creator. At the same time, the solitude of a creative work in cyberspace

  19. Conditions that Influence Drivers' Yielding Behavior for Uncontrolled Crossings

    Science.gov (United States)

    Bourquin, Eugene; Emerson, Robert Wall; Sauerburger, Dona

    2011-01-01

    Pedestrians with visual impairments need to cross streets where traffic signals and traffic signage are not present. This study examined the influences of several interventions, including a pedestrian's use of a mobility cane, on the behavior of drivers when they were expected to yield to a pedestrian crossing at an uncontrolled crossing.…

  20. Processes on Uncontrolled Aerodromes and Safety Indicators - Part I

    Directory of Open Access Journals (Sweden)

    Vladimír Plos

    2013-09-01

    Full Text Available This article describes the processes that take place at the beginning of each duty of dispatcher at uncontrolled aerodromes.Thanks to modeling and analysis of these processes, there is a possible to find critical ones and implement precise targeted safety measures.

  1. Unpredictable and Uncontrollable Events: A New Perspective on Experimental Neurosis

    Science.gov (United States)

    Kihlstrom, John F.; Mineka, Susan

    1978-01-01

    Recent work has shown that unpredictable and/or uncontrollable events can produce a variety of cognitive, affective, and somatic disturbances to the organism. These disturbances are compared to and found to be quite similar to the symptoms of the classic cases of experimental neurosis described by Pavlov, Gantt, Liddell, Masserman, and Wolpe.…

  2. Term Based Comparison Metrics for Controlled and Uncontrolled Indexing Languages

    Science.gov (United States)

    Good, B. M.; Tennis, J. T.

    2009-01-01

    Introduction: We define a collection of metrics for describing and comparing sets of terms in controlled and uncontrolled indexing languages and then show how these metrics can be used to characterize a set of languages spanning folksonomies, ontologies and thesauri. Method: Metrics for term set characterization and comparison were identified and…

  3. Du caractère sociable de l’intime : le plaisir esthétique chez Kant, entre solitude et communication

    Directory of Open Access Journals (Sweden)

    Raphaël Ehrsam

    2016-11-01

    Full Text Available Dans une large mesure, du XVIIe au XVIIIe siècle, on assiste à une métamorphose théorique des rapports entre plaisir, solitude et sociabilité. Tandis qu’au XVIIe siècle (et encore chez plusieurs auteurs du XVIIIe, le plaisir est décrit comme une expérience dont le lieu principal est la sociabilité, à l’inverse de la méditation sise de préférence dans la solitude, le XVIIIe siècle réinscrit le plaisir dans l’intimité solitaire du moi et majore l’idée d’une nécessaire communauté des sujets connaissant. La caractérisation kantienne de l’expérience esthétique, comme expérience d’un plaisir qui enveloppe immédiatement une prétention à l’universalité et à la communication, apparaît dès lors comme une façon de rompre la logique de ce chiasme.

  4. Local uncontrollability for affine control systems with jumps

    Science.gov (United States)

    Treanţă, Savin

    2017-09-01

    This paper investigates affine control systems with jumps for which the ideal If(g1, …, gm) generated by the drift vector field f in the Lie algebra L(f, g1, …, gm) can be imbedded as a kernel of a linear first-order partial differential equation. It will lead us to uncontrollable affine control systems with jumps for which the corresponding reachable sets are included in explicitly described differentiable manifolds.

  5. Mucormycosis and Myiasis in Uncontrolled Diabetes: A Double Whammy

    Directory of Open Access Journals (Sweden)

    Om Prakash D Toshniwal

    2011-01-01

    Full Text Available Mucormycosis is a rare, often fatal opportunistic fungal infection that is caused by an aerobic saprophytic fungus belonging to the order mucorales and class zygomycetes. Myiasis is caused by the members of the Diptera fly family that lay eggs or larvae on food, necrotic tissue, open wounds, and unbroken skin or mucosa. We report a rare case of mucormycosis coexisting with oral myiasis in a 50-year-old woman with uncontrolled diabetes mellitus.

  6. Injury due to uncontrolled acceleration of an electric wheelchair.

    Science.gov (United States)

    Becker, D G; Washington, B V; Devlin, P M; Zook, J E; Edlich, R F

    1991-01-01

    Approximately 750,000 disabled individuals use electrical platform mobility aids (wheelchairs) for adaptive transportation. Because there are no mandatory standards for platform mobility aids and wheelchairs, these adaptive transportation aids are prone to potential design and maintenance problems. An injury caused by uncontrolled acceleration of a platform mobility aid is reported. Examination of the platform mobility aid identified a defect in its speed control regulator that has been subsequently corrected by the manufacturer.

  7. IMMUNOLOGICAL MARKERS OF UNCONTROLLED ATOPIC BRONCHIAL ASTHMA IN CHILDREN

    Directory of Open Access Journals (Sweden)

    M. V. Smolnikova

    2017-01-01

    Full Text Available Bronchial asthma is a prevalent chronic allergic disease of lungs at early ages. A priority  task in allergology  is to search  biological  markers  related  to uncontrolled atopic  bronchial asthma. Cytokines fulfill their distinct function in pathogenesis of atopic  bronchial asthma, participating at the initiation, development and persistence of allergic inflammation in airways, causing different  variations of clinical course of the disease (with  respect  to its acuteness, severity, frequency of exacerbations. The  present  work has studied  indices  of cellular  and  humoral links of immunity, as well as levels of some  pro and  anti-inflammatory cytokines in peripheral blood serum (IL-4, IL-10, IL-2 and TNFα, aiming to determine potential markers of uncontrolled atopic bronchial asthma in children. A group of Caucasian (European children was involved into the research: Cohort 1, moderate atopic  bronchial asthma with controlled course during the last 3 months (n = 59; Cohort 2, severe/moderate-severe atopic bronchial asthma with uncontrolled course of the disease within last 3 months (n = 51,  Cohort 3 – control, practically healthy  children without signs of atopy  (n = 33. All the  children included in the group with atopic  bronchial asthma underwent regular mono/combined basic therapy  at high/ intermediate therapeutic doses.  We performed a comparative analysis  of cell  population indices  reflecting certain cellular  immunity links,  and  determined significantly  lower  levels of CD3+   lymphocytes, as well as decrease in relative  and  absolute  contents of CD4+  and  CD8+  cells in the  cohort with  uncontrolled course of atopic  bronchial asthma, as compared with controlled-course cohort. When  evaluating concentrations  of cytokines in peripheral blood serum of the patients with controlled and uncontrolled atopic  bronchial asthma, we revealed  significantly  higher

  8. CAUSES OF UNCONTROLLED BLOOD PRESSURE IN THE OVER-65 POPULATION

    Directory of Open Access Journals (Sweden)

    A Khosravi

    2010-12-01

    Full Text Available Abstract  INTRODUCTION: Hypertension is a major cause of cardiovascular disease and the prevalence of hypertension shows a linear increase with aging so that it increases by 10 percent every 10 years. This study was conducted to investigate the causes of uncontrolled blood pressure in people aged over 65 years. methods: This descriptive case-control study was conducted at Isfahan Amin Hospital in 2003 on two-hundred over-65 subjects diagnosed with hypertension through a routine travel check-up for Mecca pilgrimage. After medical examinations and blood pressure measurement according to WHO standards, the subjects were divided into a case group (controlled blood pressure and a control group (uncontrolled blood pressure, respectively. A questionnaire was filled in for each subject and the data were analyzed with χ2 and t-student test. results: The case and control groups had mean ages of 70.7±5.2 and 69.5±4.9 years, respectively. In the case group, less than half of the subjects were taking their antihypertensive medications regularly and 12.5% engaged in self-therapy. Fifty-five percent of subjects in the case group expressed a lack of motivation as the reason for discontinuing therapy. Their knowledge and practice were also found to be significantly lower than the control group (P<0.05. Discussion: In comparison with other studies, it was observed that the most common causes of uncontrolled blood pressure are poor knowledge, inappropriate practice in avoiding risk factors, and the discontinuation of pharmaceutical antihypertensive therapy.Keywords . Hypertension . Cardiovascular diseases . Antihypertensive agents . Diet therapy

  9. Essential uncontrollability of discrete linear, time-invariant, dynamical systems

    Science.gov (United States)

    Cliff, E. M.

    1975-01-01

    The concept of a 'best approximating m-dimensional subspace' for a given set of vectors in n-dimensional whole space is introduced. Such a subspace is easily described in terms of the eigenvectors of an associated Gram matrix. This technique is used to approximate an achievable set for a discrete linear time-invariant dynamical system. This approximation characterizes the part of the state space that may be reached using modest levels of control. If the achievable set can be closely approximated by a proper subspace of the whole space then the system is 'essentially uncontrollable'. The notion finds application in studies of failure-tolerant systems, and in decoupling.

  10. Pediatric intensive care treatment of uncontrolled status epilepticus.

    Science.gov (United States)

    Wilkes, Ryan; Tasker, Robert C

    2013-04-01

    The critically ill mechanically ventilated child with ongoing seizures that are refractory to any treatment presents a distinct challenge in pediatric neurocritical care. The evidence base from randomized controlled trials on which anti-epileptic drug (AED) strategy should be used is inadequate. This review of refractory and super-refractory status epilepticus summarizes recent pediatric case series regarding definitions, the second-tier AED therapies once initial anticonvulsants have failed, and the experience of high-dose midazolam, barbiturate anesthesia, and volatile anesthetics for uncontrolled status epilepticus. Copyright © 2013 Elsevier Inc. All rights reserved.

  11. Calculation of research reactor RA power at uncontrolled reactivity changes

    International Nuclear Information System (INIS)

    Cupac, S.

    1978-01-01

    The safety analysis of research reactor RA involves also the calculation of reactor power at uncontrolled reactivity changes. The corresponding computer code, based on Point Kinetics Model has been made. The short review of method applied for solving kinetic equations is given and several examples illustrating the reactor behaviour at various reactivity changes are presented. The results already obtained are giving rather rough picture of reactor behaviour in considered situations. This is the consequence of using simplified feed back and reactor cooling models, as well as temperature reactivity coefficients, which do not correspond to the actual reactor RA structure (which is now only partly fulfilled with 80% enriched uranium fuel). (author) [sr

  12. Robust Crop and Weed Segmentation under Uncontrolled Outdoor Illumination

    Directory of Open Access Journals (Sweden)

    Hong Y. Jeon

    2011-06-01

    Full Text Available An image processing algorithm for detecting individual weeds was developed and evaluated. Weed detection processes included were normalized excessive green conversion, statistical threshold value estimation, adaptive image segmentation, median filter, morphological feature calculation and Artificial Neural Network (ANN. The developed algorithm was validated for its ability to identify and detect weeds and crop plants under uncontrolled outdoor illuminations. A machine vision implementing field robot captured field images under outdoor illuminations and the image processing algorithm automatically processed them without manual adjustment. The errors of the algorithm, when processing 666 field images, ranged from 2.1 to 2.9%. The ANN correctly detected 72.6% of crop plants from the identified plants, and considered the rest as weeds. However, the ANN identification rates for crop plants were improved up to 95.1% by addressing the error sources in the algorithm. The developed weed detection and image processing algorithm provides a novel method to identify plants against soil background under the uncontrolled outdoor illuminations, and to differentiate weeds from crop plants. Thus, the proposed new machine vision and processing algorithm may be useful for outdoor applications including plant specific direct applications (PSDA.

  13. Predictability of uncontrollable multifocal seizures - towards new treatment options

    Science.gov (United States)

    Lehnertz, Klaus; Dickten, Henning; Porz, Stephan; Helmstaedter, Christoph; Elger, Christian E.

    2016-04-01

    Drug-resistant, multifocal, non-resectable epilepsies are among the most difficult epileptic disorders to manage. An approach to control previously uncontrollable seizures in epilepsy patients would consist of identifying seizure precursors in critical brain areas combined with delivering a counteracting influence to prevent seizure generation. Predictability of seizures with acceptable levels of sensitivity and specificity, even in an ambulatory setting, has been repeatedly shown, however, in patients with a single seizure focus only. We did a study to assess feasibility of state-of-the-art, electroencephalogram-based seizure-prediction techniques in patients with uncontrollable multifocal seizures. We obtained significant predictive information about upcoming seizures in more than two thirds of patients. Unexpectedly, the emergence of seizure precursors was confined to non-affected brain areas. Our findings clearly indicate that epileptic networks, spanning lobes and hemispheres, underlie generation of seizures. Our proof-of-concept study is an important milestone towards new therapeutic strategies based on seizure-prediction techniques for clinical practice.

  14. Remote RemoteRemoteRemote sensing potential for sensing ...

    African Journals Online (AJOL)

    Remote RemoteRemoteRemote sensing potential for sensing potential for sensing potential for sensing potential for sensing potential for sensing potential for sensing potential for sensing potential for sensing potential for sensing potential for sensing p. A Ngie, F Ahmed, K Abutaleb ...

  15. Narraciones de Cien Años de Soledad Acerca del Conflicto Armado y la Violencia Política en Colombia (Naratives of One Hundred Years of Solitude About the Armed Conflict and Political Violence in Colombia)

    OpenAIRE

    Camilo Eduardo Umaña Hernández

    2014-01-01

    This paper intends to explore the narrations of the conflict and political violence embedded in the novel One hundred years of solitude by Gabriel Garcia Marquez. As one of the most important Colombian books of the last century, “One Hundred years of Solitude” evidences the magical narrative and imagination of the Caribbean as well as the reality of life, death, family, love, work, social conflicts and other aspects that are relevant for understanding and exploring the perceptions...

  16. Facial Recognition in Uncontrolled Conditions for Information Security

    Science.gov (United States)

    Xiao, Qinghan; Yang, Xue-Dong

    2010-12-01

    With the increasing use of computers nowadays, information security is becoming an important issue for private companies and government organizations. Various security technologies have been developed, such as authentication, authorization, and auditing. However, once a user logs on, it is assumed that the system would be controlled by the same person. To address this flaw, we developed a demonstration system that uses facial recognition technology to periodically verify the identity of the user. If the authenticated user's face disappears, the system automatically performs a log-off or screen-lock operation. This paper presents our further efforts in developing image preprocessing algorithms and dealing with angled facial images. The objective is to improve the accuracy of facial recognition under uncontrolled conditions. To compare the results with others, the frontal pose subset of the Face Recognition Technology (FERET) database was used for the test. The experiments showed that the proposed algorithms provided promising results.

  17. Facial Recognition in Uncontrolled Conditions for Information Security

    Directory of Open Access Journals (Sweden)

    Qinghan Xiao

    2010-01-01

    Full Text Available With the increasing use of computers nowadays, information security is becoming an important issue for private companies and government organizations. Various security technologies have been developed, such as authentication, authorization, and auditing. However, once a user logs on, it is assumed that the system would be controlled by the same person. To address this flaw, we developed a demonstration system that uses facial recognition technology to periodically verify the identity of the user. If the authenticated user's face disappears, the system automatically performs a log-off or screen-lock operation. This paper presents our further efforts in developing image preprocessing algorithms and dealing with angled facial images. The objective is to improve the accuracy of facial recognition under uncontrolled conditions. To compare the results with others, the frontal pose subset of the Face Recognition Technology (FERET database was used for the test. The experiments showed that the proposed algorithms provided promising results.

  18. Remote Research

    CERN Document Server

    Tulathimutte, Tony

    2011-01-01

    Remote studies allow you to recruit subjects quickly, cheaply, and immediately, and give you the opportunity to observe users as they behave naturally in their own environment. In Remote Research, Nate Bolt and Tony Tulathimutte teach you how to design and conduct remote research studies, top to bottom, with little more than a phone and a laptop.

  19. Remote Sensing

    CERN Document Server

    Khorram, Siamak; Koch, Frank H; van der Wiele, Cynthia F

    2012-01-01

    Remote Sensing provides information on how remote sensing relates to the natural resources inventory, management, and monitoring, as well as environmental concerns. It explains the role of this new technology in current global challenges. "Remote Sensing" will discuss remotely sensed data application payloads and platforms, along with the methodologies involving image processing techniques as applied to remotely sensed data. This title provides information on image classification techniques and image registration, data integration, and data fusion techniques. How this technology applies to natural resources and environmental concerns will also be discussed.

  20. The role of the verbal periphrasis haber de + infinitive in the temporal structure of the novel One Hundred Years of Solitude

    Directory of Open Access Journals (Sweden)

    Jasmina Markič

    2012-12-01

    Full Text Available The article analyzes some temporal and aspectual values (past future, imminence of an event intermingled with modal values (epistemic values of obligation, necessity and probability of the Spanish verbal periphrasis haber de + infinitive which convey very special stylistic values and meanings in Gabriel García Márquez´s novel One Hundred Years of Solitude. Haber de + infinitive (in the imperfect tense of the indicative: había de + infinitive introduces the first sentence and activates the events in the novel, giving them a particular temporal and spatial frame. Through the narrative techniques of flashback and flash forward – present in this novel in which the dominant theme is time and the inevitable repetition of history in Macondo – the above-mentioned verbal periphrasis plays an important role in signalling events that can be neither avoided nor stopped. With its strong expressive force, and due to its basic temporal and modal meanings, the verbal periphrasis haber de + infinitive has a premonitory function in the novel: it predicts fatal events in the lives of the inhabitants of Macondo – inhabitants who are controlled by their pasts and the complexity of time – and in the history of the town, which seems to be doomed and predetermined in its very existence.

  1. Uncontrolled withdrawal of a control rod without scram

    International Nuclear Information System (INIS)

    Abou-EL-Maaty, Talal

    2008-01-01

    In the present work the thermal-hydraulics of reactivity-induced transients in low enriched uranium (LEU) core of a typical material test research reactor (MTR) are analyzed using the previous program developed by Khater et al. The analysis was done for uncontrolled withdrawal of a control rod with scram-disabled conditions. Initiating reactivity events with and without the influence of reactivity efficiency curve ('S' curve) were considered. The results of the proposed transients are analyzed and compared with each other. In transient without the 'S' curve influence, a high primary peak power of 406.18 MW is attained and a clad melt down takes place after 1.85 s. In the transient with the 'S' curve influence, a high super prompt-critical situation is produced (1.762$ at 0.895 s) with a very high primary peak power of 801.05 MW at 0.912 s. Also, a fast clad melt down is resulted in the hot channel at 1.088 s and a stable film boiling is established. This study indicates that, compared to the application of linear reactivity curve, the application of the reactivity efficiency curve results in the prediction of higher peaks in power and temperatures (fuel, clad and coolant) with a fast clad melt down

  2. Uncontrolled withdrawal of a control rod without SCRAM

    International Nuclear Information System (INIS)

    Abou-El-Maaty, T.

    2007-01-01

    In the present work, the thermal-hydraulic analysis of reactivity-induced transients in a Low Enriched Uranium (LEU) core of a typical material test research reactor is conducted using the previous program developed Khater et al. The analysis was done for the uncontrolled withdrawal of a control rod under scram-disabled conditions. The initiating event reactivity was considered with and without influence of the reactivity efficiency curve (''S'' curve). The results of the transient calculations are analyzed and compared with each other. In the transient without the ''S'' curve influence, a high primary peak power of 406.18 MW is attained and a clad melt down is occurring after 1.85 s. In the transient with the ''S'' curve influence, a super prompt highly critical situation is produced (1.762 $ at 0.895 s) with a very high primary peak power of 801.05 MW at 0.912 s. A fast clad melt down is resulting in the hot channel at 1.088 s and a stable film boiling is occurring. This study shows that the influence of the reactivity efficiency curve results in higher peaks in power and temperatures (fuel, clad and coolant) with a fast clad melt down than that of a linear assumption. (orig.)

  3. Flies cope with uncontrollable stress by learned helplessness.

    Science.gov (United States)

    Yang, Zhenghong; Bertolucci, Franco; Wolf, Reinhard; Heisenberg, Martin

    2013-05-06

    In a wide range of animals, uncontrollable stressful events can induce a condition called "learned helplessness." In mammals it is associated with low general activity, poor learning, disorders of sleep and feeding, ulcers, and reduced immune status, as well as with increased serotonin in parts of the brain. It is considered an animal model of depression in humans. Here we investigate learned helplessness in Drosophila, showing that this behavioral state consists of a cognitive and a modulatory, possibly mood-like, component. A fly, getting heated as soon as it stops walking, reliably resumes walking to escape the heat. If, in contrast, the fly is not in control of the heat, it learns that its behavior has no effect and quits responding. In this state, the fly walks slowly and takes longer and more frequent rests, as if it were "depressed." This downregulation of walking behavior is more pronounced in females than in males. Learned helplessness in Drosophila is an example of how, in a certain situation, behavior is organized according to its expected consequences. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. An algorithmic approach for the treatment of severe uncontrolled asthma

    Science.gov (United States)

    Zervas, Eleftherios; Samitas, Konstantinos; Papaioannou, Andriana I.; Bakakos, Petros; Loukides, Stelios; Gaga, Mina

    2018-01-01

    A small subgroup of patients with asthma suffers from severe disease that is either partially controlled or uncontrolled despite intensive, guideline-based treatment. These patients have significantly impaired quality of life and although they constitute asthma patients, they are responsible for more than half of asthma-related healthcare costs. Here, we review a definition for severe asthma and present all therapeutic options currently available for these severe asthma patients. Moreover, we suggest a specific algorithmic treatment approach for the management of severe, difficult-to-treat asthma based on specific phenotype characteristics and biomarkers. The diagnosis and management of severe asthma requires specialised experience, time and effort to comprehend the needs and expectations of each individual patient and incorporate those as well as his/her specific phenotype characteristics into the management planning. Although some new treatment options are currently available for these patients, there is still a need for further research into severe asthma and yet more treatment options. PMID:29531957

  5. Model-Based Illumination Correction for Face Images in Uncontrolled Scenarios

    NARCIS (Netherlands)

    Boom, B.J.; Spreeuwers, Lieuwe Jan; Veldhuis, Raymond N.J.

    2009-01-01

    Face Recognition under uncontrolled illumination conditions is partly an unsolved problem. Several illumination correction methods have been proposed, but these are usually tested on illumination conditions created in a laboratory. Our focus is more on uncontrolled conditions. We use the Phong model

  6. CONTROL ALGORITMS OF BOF MELTING WITH CONSIDERING THE INFLUENCE OF UNCONTROLLED DISTURBANCE

    Directory of Open Access Journals (Sweden)

    V. S. Bogushevsky

    2016-01-01

    Full Text Available The article describes influence of uncontrollable disturbances for output parameters of converting smelting. You also find numerical values of impact impurity of scrap, falling mixer slag with cast iron, limestone instead of lime and water from cooled elements on decarbonization, bathtub temperature and slag basicity. Created a control algorithm with the influence of uncontrolled disturbance.

  7. Getting the basics right resolves most cases of uncontrolled and problematic asthma

    NARCIS (Netherlands)

    de Groot, Eric P.; Kreggemeijer, Wendy J.; Brand, Paul L. P.

    AimThe prevalence of true therapy-resistant asthma among children whose asthma remains uncontrolled, despite daily controller therapy, is unknown. The aim of this study was to investigate the underlying causes in children with uncontrolled asthma. MethodsThis was a retrospective chart review of 142

  8. Albuminuria and masked uncontrolled hypertension in chronic kidney disease.

    Science.gov (United States)

    Agarwal, Rajiv

    2017-12-01

    Masked uncontrolled hypertension (MUCH) is associated with greater target organ damage such as left ventricular hypertrophy, increased arterial stiffness and albuminuria. Whether MUCH independently associates with greater cardiovascular end-organ damage or kidney damage is unclear. The objective of this study was to assess the strength of the relationship of MUCH (awake ambulatory blood pressure ≥135/85 mmHg and clinic blood pressure <140/90 mmHg) with target organ damage. In a cross-sectional study at a veterans' administration medical center, clinically normotensive veterans without chronic kidney disease (CKD) (n = 29) and 287 patients with CKD and controlled hypertension (CH, n = 193), MUCH (n = 67) and uncontrolled hypertension (UCH, n = 27) had evaluation of target organ damage. Target organ damage was measured by echocardiography [left ventricular mass index (LVMI)], arterial ultrasonography [aortic pulse wave velocity (PWV)] and 24-h urine collection [albuminuria (urine albumin to creatinine ratio)] in all participants. Compared to that of controls, LVMI was higher by 21.8 g/m2 (CI, 4.0-39.7 g/m2) in CH, 27.9 (CI, 8-47.8) in MUCH and 39.5 (CI, 15.7-63.2) in UCH (P < 0.01 for group differences, P < 0.01 for linear trend). Although differences persisted after adjustment for age, sex and race, they lost significance after adjustments for cardiovascular risk factors and their treatment. Compared to that of controls, PWV was different among CH, MUCH and UCH (P = 0.04 for group differences, P = 0.02 for linear trend). However, differences lost significance after adjustments for age, sex and race. Compared to that of controls, log2 UACR was higher by 2.40 mg/mg (CI, 1.28-3.52) in CH, 4.94 (CI, 3.70-6.18) in MUCH and 6.01 (CI, 4.49-7.53) in UCH (P < 0.0001 for group difference, P < 0.0001 for linear trend). Differences persisted after adjustment for age, sex and race, cardiovascular risk factors and their treatment and cardiovascular disease (P < 0.0001 for group

  9. Dynamic Determinants of the Uncontrolled Manifold during Human Quiet Stance.

    Science.gov (United States)

    Suzuki, Yasuyuki; Morimoto, Hiroki; Kiyono, Ken; Morasso, Pietro G; Nomura, Taishin

    2016-01-01

    Human postural sway during stance arises from coordinated multi-joint movements. Thus, a sway trajectory represented by a time-varying postural vector in the multiple-joint-angle-space tends to be constrained to a low-dimensional subspace. It has been proposed that the subspace corresponds to a manifold defined by a kinematic constraint, such that the position of the center of mass (CoM) of the whole body is constant in time, referred to as the kinematic uncontrolled manifold ( kinematic-UCM ). A control strategy related to this hypothesis ( CoM-control-strategy ) claims that the central nervous system (CNS) aims to keep the posture close to the kinematic-UCM using a continuous feedback controller, leading to sway patterns that mostly occur within the kinematic-UCM, where no corrective control is exerted. An alternative strategy proposed by the authors ( intermittent control-strategy ) claims that the CNS stabilizes posture by intermittently suspending the active feedback controller, in such a way to allow the CNS to exploit a stable manifold of the saddle-type upright equilibrium in the state-space of the system, referred to as the dynamic-UCM , when the state point is on or near the manifold. Although the mathematical definitions of the kinematic- and dynamic-UCM are completely different, both UCMs play similar roles in the stabilization of multi-joint upright posture. The purpose of this study was to compare the dynamic performance of the two control strategies. In particular, we considered a double-inverted-pendulum-model of postural control, and analyzed the two UCMs defined above. We first showed that the geometric configurations of the two UCMs are almost identical. We then investigated whether the UCM-component of experimental sway could be considered as passive dynamics with no active control, and showed that such UCM-component mainly consists of high frequency oscillations above 1 Hz, corresponding to anti-phase coordination between the ankle and hip. We

  10. Dynamic determinants of the uncontrolled manifold during human quiet stance

    Directory of Open Access Journals (Sweden)

    Yasuyuki Suzuki

    2016-12-01

    Full Text Available Human postural sway during stance arises from coordinated multi-joint movements. Thus, a sway trajectory represented by a time-varying postural vector in the multiple-joint-angle-space tends to be constrained to a low-dimensional subspace. It has been proposed that the subspace corresponds to a manifold defined by a kinematic constraint, such that the position of the center of mass (CoM of the whole body is constant in time, referred to as the kinematic uncontrolled manifold (kinematic-UCM. A control strategy related to this hypothesis (CoM-control-strategy claims that the central nervous system (CNS aims to keep the posture close to the kinematic-UCM using a continuous feedback controller, leading to sway patterns that mostly occur within the kinematic-UCM, where no corrective control is exerted. An alternative strategy proposed by the authors (intermittent control-strategy claims that the CNS stabilizes posture by intermittently suspending the active feedback controller, in such a way to allow the CNS to exploit a stable manifold of the saddle-type upright equilibrium in the state-space of the system, referred to as the dynamic-UCM, when the state point is on or near the manifold. Although the mathematical definitions of the kinematic- and dynamic-UCM are completely different, both UCMs play similar roles in the stabilization of multi-joint upright posture. The purpose of this study was to compare the dynamic performance of the two control strategies. In particular, we considered a double-inverted-pendulum-model of postural control, and analyzed the two UCMs defined above. We first showed that the geometric configurations of the two UCMs are almost identical. We then investigated whether the UCM-component of experimental sway could be considered as passive dynamics with no active control, and showed that such UCM-component mainly consists of high frequency oscillations above 1 Hz, corresponding to anti-phase coordination between the ankle and

  11. RItA: The Italian severe/uncontrolled asthma registry.

    Science.gov (United States)

    Maio, S; Baldacci, S; Bresciani, M; Simoni, M; Latorre, M; Murgia, N; Spinozzi, F; Braschi, M; Antonicelli, L; Brunetto, B; Iacovacci, P; Roazzi, P; Pini, C; Pata, M; La Grasta, L; Paggiaro, P; Viegi, G

    2018-03-01

    The Italian severe/uncontrolled asthma (SUA) web-based registry encompasses demographic, clinical, functional, and inflammatory data; it aims to raise SUA awareness, identifying specific phenotypes and promoting optimal care. Four hundred and ninety three adult patients from 27 Italian centers (recruited in 2011-2014) were analyzed. Mean age was 53.8 years. SUA patients were more frequently female (60.6%), with allergic asthma (83.1%). About 30% showed late onset of asthma diagnosis/symptoms (>40 years); the mean age for asthma symptoms onset was 30.2 years and for asthma diagnosis 34.4 years. 97.1% used ICS (dose 2000 BDP), 93.6% LABA in association with ICS, 53.3% LTRAs, 64.1% anti-IgE, 10.7% theophylline, and 16.0% oral corticosteroids. Mean FEV 1 % pred of 75.1%, median values of 300/mm 3 of blood eosinophil count, 323 kU/L of serum total IgE, and 24 ppb of FENO were shown. Most common comorbidities were allergic rhinitis (62.4%), gastroesophageal reflux (42.1%), sinusitis (37.9%), nasal polyposis (30.2%), and allergic conjunctivitis (30.2%). 55.7% of SUA patients had exacerbations in the last 12 months, 9.7% emergency department visits, and 7.3% hospitalizations. Factors associated with exacerbation risk were obesity (OR, 95% CI 2.46, 1.11-5.41), psychic disorders (2.87, 0.89-9.30-borderline), nasal polyps (1.86, 0.88-3.89-borderline), partial/poor asthma treatment adherence (2.54, 0.97-6.67-borderline), and anti-IgE use in a protective way (0.26, 0.12-0.53). Comparisons to severe asthma multicenter studies and available registries showed data consistency across European and American populations. An international effort in the implementation of SUA patients' registries could help to better understand the clinical features and to manage severe asthma, representing a non-negligible socioeconomic burden for health services. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  12. Uncontrolled hypertension is associated with coronary artery calcification and electrocardiographic left ventricular hypertrophy

    DEFF Research Database (Denmark)

    Nielsen, Mette Lundgren; Pareek, Manan; Gerke, O

    2015-01-01

    We conducted a 1:2 matched case-control study in order to evaluate whether the prevalence of coronary artery calcium (CAC) and electrocardiographic left ventricular hypertrophy (LVH) or strain was higher in patients with uncontrolled hypertension than in subjects from the general population......, and evaluate the association between CAC and LVH in patients with uncontrolled hypertension. Cases were patients with uncontrolled hypertension, whereas the controls were random individuals from the general population without cardiovascular disease. CAC score was assessed using a non-contrast computed...

  13. Physical Growth and Body Composition of Controlled Versus Uncontrolled Type 1 Egyptian Diabetic Children

    Directory of Open Access Journals (Sweden)

    Nayera E. Hassan

    2014-12-01

    CONCLUSION: Growth was compromised in uncontrolled T1DM children. This is of utmost importance since most of the clinical features are reversible with better glycemic control and appropriate insulin management.

  14. Analysis of means of improving the uncontrolled lateral motions of personal airplanes

    Science.gov (United States)

    Mckinney, Marion O , Jr

    1951-01-01

    A theoretical analysis has been made of means of improving the uncontrolled motions of personal airplanes. The purpose of this investigation was to determine whether such airplanes could be made to fly uncontrolled for an indefinite period of time without getting into dangerous attitudes and for a reasonable period of time (1 to 3 min) without deviating excessively from their original course. The results of this analysis indicated that the uncontrolled motions of a personal airplane could be made safe as regards spiral tendencies and could be greatly improved as regards maintenance of course without resort to an autopilot. The only way to make the uncontrolled motions completely satisfactory as regards continuous maintenance of course, however, is to use a conventional type of autopilot.

  15. Sudden death in young persons with uncontrolled asthma--a nationwide cohort study in Denmark

    DEFF Research Database (Denmark)

    Gullach, Anders Juul; Risgaard, Bjarke; Lynge, Thomas Hadberg

    2015-01-01

    BACKGROUND: Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled...... in preventing sudden unexpected deaths. We therefore aimed to describe clinical characteristics, symptoms, causes of death, and contact with the healthcare system prior to sudden unexpected death in young persons with uncontrolled asthma. METHODS: Through the review of death certificates, we found 625 sudden...... individuals who suffered from uncontrolled asthma. This corresponds to an incidence rate of 0.32 per 100,000 person-years. The cause of death in 31 cases (63%) was sudden cardiac death, and in 13 cases (27%), it was a fatal asthma attack. Symptoms (chest pain, dyspnea, seizures, general malaise, syncope...

  16. Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

    Directory of Open Access Journals (Sweden)

    L.A. Santos

    2007-07-01

    Full Text Available Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled. Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70 and hospitalization (US$86.30 vs US$12.88], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2% and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system.

  17. Home based telemedicine intervention for patients with uncontrolled hypertension: - a real life - non-randomized study

    Science.gov (United States)

    2014-01-01

    therapy initiated following telephone contacts were 1.81 ± 1.73 per patient. Conclusions The addition of a structured physician-nurse approach supported by remote telemonitoring of blood pressure is likely to improve outcome in patients with uncontrolled hypertension. PMID:24920046

  18. Symbolism, solitude and modernity: science and scientists in porfirian Mexico Simbolismo, solidão e modernidade: ciência e cientistas no México porfiriano

    Directory of Open Access Journals (Sweden)

    Natalia Priego

    2008-06-01

    Full Text Available The quest of Mexico for a distinctive national identity throughout the 19th century reached a climax during the period known as the Porfiriato, one of the principal features of which was the deep desire of Porfirio Díaz and his circle to turn Mexico into a 'modern' country perhaps without a clear definition of the meaning of this concept. The debate about national identity had addressed such issues as the rejection of indigenous cultures, blind passion for French culture, and how to go about criating a modern nation by means of industrialization and scientific modernization. The concept of nation in Mexico is definitively linked with the search for a national 'I', and with the struggle to overcome the solitude identified by Octavio Paz. Paradoxically, this very quest forms a part of this identity, and it seems to remain inconclusive.Ao longo do século XIX, a tentativa de construir uma identidade nacional para o México atingiu seu ápice no período conhecido como Porfiriato, que teve como uma das principais características o desejo profundo de Porfírio Díaz e seu grupo de transformar o país em uma nação moderna, sem ter uma definição clara do significado desse conceito. O debate sobre identidade nacional tinha enfrentado questões como a negação de culturas indígenas; a paixão cega pela cultura francesa e todo um savoir faire diante do esforço de se criar uma nação moderna através da industrialização e da modernização científica. O conceito de nação, no México, é estreitamente vinculado à busca pelo 'eu' nacional e à luta para ultrapassar a solidão descrita por Octávio Paz. Paradoxalmente, esta busca forma uma parte dessa identidade, e parece inconclusa.

  19. Remote viewing.

    Science.gov (United States)

    Scott, C

    1988-04-15

    Remote viewing is the supposed faculty which enables a percipient, sited in a closed room, to describe the perceptions of a remote agent visiting an unknown target site. To provide convincing demonstration of such a faculty poses a range of experimental and practical problems, especially if feedback to the percipient is allowed after each trial. The precautions needed are elaborate and troublesome; many potential loopholes have to be plugged and there will be strong temptations to relax standards, requiring exceptional discipline and dedication by the experimenters. Most reports of remote viewing experiments are rather superficial and do not permit assessment of the experimental procedures with confidence; in many cases there is clear evidence of particular loopholes left unclosed. Any serious appraisal of the evidence would have to go beyond the reports. Meanwhile the published evidence is far from compelling, and certainly insufficient to justify overthrow of well-established scientific principles.

  20. Determinants of Uncontrolled Hypertension in Rural Communities in South Asia - Bangladesh, Pakistan, and Sri Lanka.

    Science.gov (United States)

    Jafar, Tazeen H; Gandhi, Mihir; Jehan, Imtiaz; Naheed, Aliya; de Silva, H Asita; Shahab, Hunaina; Alam, Dewan; Luke, Nathasha; Lim, Ching Wee

    2018-04-26

    Uncontrolled blood pressure (BP) is a leading risk factor for death and disability in South Asia. We aimed to determine the cross-country variation, and the factors associated with uncontrolled BP among adults treated for hypertension in rural South Asia. We enrolled 1718 individuals aged ≥40 years treated for hypertension in a cross-sectional study from rural communities in Bangladesh, Pakistan, and Sri Lanka. Multivariable logistic regression model was used to determine the factors associated with uncontrolled BP (systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg). Among hypertensive individuals, 58.0% (95% confidence interval 55.7, 60.4) had uncontrolled BP: 52.8% (49.0, 56.6) in Bangladesh, 70.6% (65.7, 75.1) in Pakistan, and 56.5% (52.7, 60.1) in Sri Lanka. The odds (odds ratio (95% confidence interval)) of uncontrolled BP were significantly higher in individuals with lower wealth index (1.17 (1.02, 1.35)); single vs married (1.46 (1.10, 1.93)); higher log urine albumin-to-creatinine ratio (1.41 (1.24, 1.60)); lower estimated glomerular filtration rate (1.23 (1.01, 1.49)); low vs high adherence to antihypertensive medication (1.50 (1.16, 1.94)); and Pakistan (2.91 (1.60, 5.28)) vs Sri Lanka. However, the odds were lower in those with vs without self-reported kidney disease (0.51 (0.28, 0.91)); and receiving vs not receiving statins (0.62 (0.44, 0.87)). The majority of individuals with treated hypertension have uncontrolled BP in rural Bangladesh, Pakistan, and Sri Lanka with significant disparities among and within countries. Urgent public health efforts are needed to improve access and adherence to antihypertensive medications in disadvantaged populations in rural South Asia.

  1. Racial/ethnic disparity in the associations of smoking status with uncontrolled hypertension subtypes among hypertensive subjects.

    Science.gov (United States)

    Liu, Xuefeng; Zhu, Tinghui; Manojlovich, Milisa; Cohen, Hillel W; Tsilimingras, Dennis

    2017-01-01

    Racial/ethnic differences in the associations of smoking with uncontrolled blood pressure (BP) and its subtypes (isolated uncontrolled systolic BP (SBP), uncontrolled systolic-diastolic BP, and isolated uncontrolled diastolic BP (DBP)) have not been investigated among diagnosed hypertensive subjects. A sample of 7,586 hypertensive patients aged ≥18 years were selected from the National Health and Nutrition Examination Survey 1999-2010. Race/ethnicity was classified into Hispanic, non-Hispanic white, and non-Hispanic black. Smoking was categorized as never smoking, ex-smoking, and current smoking. Uncontrolled BP was determined as SBP≥140 or DBP≥90 mm Hg. Isolated uncontrolled SBP was defined as SBP≥140 and DBPsmokers, current smokers were 29% less likely to have uncontrolled BP in non-Hispanic whites (OR = 0.71, 95% CI = 0.56-0.90), although the likelihood for uncontrolled BP is the same for smokers and never smokers in Hispanics and non-Hispanic blacks. Current smokers were 26% less likely than never smokers to have isolated uncontrolled SBP in non-Hispanic whites (OR = 0.74, 95% CI = 0.58-0.95). However, current smoking is associated with an increased likelihood of uncontrolled systolic-diastolic BP in non-Hispanic blacks, and current smokers in this group were 70% more likely to have uncontrolled systolic-diastolic BP than never smokers (OR = 1.70, 95% CI = 1.10-2.65). The associations between current smoking and uncontrolled BP differed over race/ethnicity. Health practitioners may need to be especially vigilant with non-Hispanic black smokers with diagnosed hypertension.

  2. Ten Thousand Years of Solitude?

    International Nuclear Information System (INIS)

    Benford, G.; Pasqualetti, M.J.

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs

  3. Ten Thousand Years of Solitude

    Energy Technology Data Exchange (ETDEWEB)

    Benford, G. (Los Alamos National Lab., NM (USA) California Univ., Irvine, CA (USA). Dept. of Physics); Kirkwood, C.W. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA). Coll. of Business Administration); Harry, O. (Los Alamos National Lab., NM (USA)); Pasqualetti, M.J. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA))

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs.

  4. Solitude or co-existence

    DEFF Research Database (Denmark)

    Sorensen, Elsebeth Korsgaard; Voldborg, Hanne

    2017-01-01

    This study reports on research into the impact of digital technological interventions for including kids with attention and developmental deficits into school class contexts. It describes, how the authors have approached the challenge of researching inclusion of kids with attention and developmen......This study reports on research into the impact of digital technological interventions for including kids with attention and developmental deficits into school class contexts. It describes, how the authors have approached the challenge of researching inclusion of kids with attention...

  5. Factors associated with lack of awareness and uncontrolled high blood pressure among Canadian adults with hypertension.

    Science.gov (United States)

    Gee, Marianne E; Bienek, Asako; McAlister, Finlay A; Robitaille, Cynthia; Joffres, Michel; Tremblay, Mark S; Johansen, Helen; Campbell, Norm R C

    2012-05-01

    Approximately 17% of Canadians with high blood pressure were unaware of their condition, and of Canadians aware of having the condition, approximately 1 in 5 have uncontrolled high blood pressure despite high rates of pharmacotherapy. The objectives of the current study are to estimate the prevalence of resistant hypertension and examine factors associated with (1) lack of awareness and (2) uncontrolled hypertension despite pharmacotherapy. Using the 2007-2009 Canadian Health Measures Survey (N = 3473, aged 20-79 years) and logistic regression, we quantified relationships between characteristics and (1) presence of hypertension, (2) lack of awareness (among those with hypertension), and (3) uncontrolled high blood pressure (among those treated for hypertension). Older age, lowest income, and less than high school education were associated with presence of hypertension. Men (odds ratio [OR], 1.6; 95% confidence interval [CI], 1.1-2.2) and adults high blood pressure (OR, 2.4; 95% CI, 1.1-5.2) despite treatment. Elevated systolic blood pressure was the issue in over 90% of women and 80% of men with uncontrolled hypertension. Depending on the definition employed, 4.4% (95% CI, 2.4-6.4) to 7.8% (95% CI, 6.0-9.6) of the population with hypertension had resistant hypertension. Messaging or interventions encouraging screening may be helpful for all younger Canadian adults and men; programs encouraging blood pressure control may help older women. Copyright © 2012 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  6. Uncontrolled hypertension in older patients: markers and associated factors to masked and white-coat effect

    Science.gov (United States)

    Lima, Nereida KC; Moriguti, Julio C; Ferriolli, Eduardo

    2016-01-01

    Background Hypertension is the main risk factor for cardiovascular diseases, affecting more than half the elderly population. It is essential to know if they have proper control of hypertension. The aim of this study was to identify the associated factors to masked uncontrolled hypertension and false uncontrolled hypertension in older patients. Methods Two-hundred seventy-three individuals (70.1 ± 6.7 years-old) had blood pressure (BP) measured at the office and by ambulatory BP monitoring (ABPM), with the definition of controlled group (C), individuals with high office BP and adequate ABPM, called white-coat effect group (WCE), uncontrolled (UC), and subjects with appropriate office BP and elevated ABPM denominated masked effect group (ME). Age, body mass index, diabetes, pulse pressure (PP) and BP dipping during sleep were evaluated (Kruskal-Wallis test and logistic regression models). Results Age was higher in UC than in C and ME (P ABPM PP was lower in C (48 ± 7 mmHg) and WCE (51 ± 6 mmHg) than in UC (67 ± 12 mmHg) and ME (59 ± 8 mmHg) (P ABPM favored the identification of a higher PP and a lower BP dipping during sleep in the masked effect and uncontrolled groups. PMID:27781057

  7. Effects of food on cortisol and mood in vulnerable subjects under controllable and uncontrollable stress

    NARCIS (Netherlands)

    Markus, R.; Panhuysen, G.; Tuiten, A.; Koppeschaar, H.

    2000-01-01

    The aim of this study was to investigate whether in stress-prone subjects, carbohydrate-rich, protein-poor food (CR/PP) diminished depressive mood and a cortisol response under controllable as well as uncontrollable laboratory stress. Twenty-two subjects with high stress proneness (HS) and 23

  8. Managing the uncontrollable: Empirical studies of user-generated content online

    NARCIS (Netherlands)

    Lee, H.H.

    2014-01-01

    Addressing "uncontrollability' of online buzz, this thesis examines unstructured user-generated content in response to corporate social responsibility communications in the blogosphere and explores the content of company-administered co-creation communities. Analyzing text-based content online, the

  9. Young-Age Gender Differences in Mathematics Mediated by Independent Control or Uncontrollability

    Science.gov (United States)

    Zirk-Sadowski, Jan; Lamptey, Charlotte; Devine, Amy; Haggard, Mark; Szucs, Dénes

    2014-01-01

    We studied whether the origins of math anxiety can be related to a biologically supported framework of stress induction: (un)controllability perception, here indicated by self-reported independent efforts in mathematics. Math anxiety was tested in 182 children (8- to 11-year-olds). "Latent factor modeling" was used to test hypotheses on…

  10. Environment mapping and localization with an uncontrolled swarm of ultrasound sensor motes

    NARCIS (Netherlands)

    Duisterwinkel, E.; Demi, L.; Dubbelman, G.; Talnishnikh, E.; Wörtche, H.J.; Bergmans, J.W.M.

    2014-01-01

    A method is presented in which a (large) swarm of sensor motes perform simple ultrasonic ranging measurements. The method allows to localize the motes within the swarm, and at the same time, map the environment which the swarm has traversed. The motes float passively uncontrolled through the

  11. Racial/ethnic disparity in the associations of smoking status with uncontrolled hypertension subtypes among hypertensive subjects.

    Directory of Open Access Journals (Sweden)

    Xuefeng Liu

    Full Text Available Racial/ethnic differences in the associations of smoking with uncontrolled blood pressure (BP and its subtypes (isolated uncontrolled systolic BP (SBP, uncontrolled systolic-diastolic BP, and isolated uncontrolled diastolic BP (DBP have not been investigated among diagnosed hypertensive subjects.A sample of 7,586 hypertensive patients aged ≥18 years were selected from the National Health and Nutrition Examination Survey 1999-2010. Race/ethnicity was classified into Hispanic, non-Hispanic white, and non-Hispanic black. Smoking was categorized as never smoking, ex-smoking, and current smoking. Uncontrolled BP was determined as SBP≥140 or DBP≥90 mm Hg. Isolated uncontrolled SBP was defined as SBP≥140 and DBP<90 mm Hg, uncontrolled SDBP as SBP≥140 and DBP≥90 mm Hg, and isolated uncontrolled DBP as SBP<140 and DBP≥90 mm Hg. Adjusted odds ratios (ORs with 95% confidence intervals (CIs of uncontrolled BP and its subtypes were calculated using weighted logistic regression models.The interaction effect of race and smoking was significant after adjustment for the full potential confounding covariates (Adjusted p = 0.0412. Compared to never smokers, current smokers were 29% less likely to have uncontrolled BP in non-Hispanic whites (OR = 0.71, 95% CI = 0.56-0.90, although the likelihood for uncontrolled BP is the same for smokers and never smokers in Hispanics and non-Hispanic blacks. Current smokers were 26% less likely than never smokers to have isolated uncontrolled SBP in non-Hispanic whites (OR = 0.74, 95% CI = 0.58-0.95. However, current smoking is associated with an increased likelihood of uncontrolled systolic-diastolic BP in non-Hispanic blacks, and current smokers in this group were 70% more likely to have uncontrolled systolic-diastolic BP than never smokers (OR = 1.70, 95% CI = 1.10-2.65.The associations between current smoking and uncontrolled BP differed over race/ethnicity. Health practitioners may need to be especially

  12. Eating traits questionnaires as a continuum of a single concept. Uncontrolled eating.

    Science.gov (United States)

    Vainik, Uku; Neseliler, Selin; Konstabel, Kenn; Fellows, Lesley K; Dagher, Alain

    2015-07-01

    Research on eating behaviour has identified several potentially relevant eating-related traits captured by different questionnaires. Often, these questionnaires predict Body Mass Index (BMI), but the relationship between them has not been explicitly studied. We studied the unity and diversity of questionnaires capturing five common eating-related traits: Power of Food, Eating Impulsivity, emotional eating, Disinhibition, and binge eating in women from Estonia (n = 740) and Canada (n = 456). Using bifactor analysis, we showed that a) these questionnaires are largely explained by a single factor, and b) relative to this shared factor, only some questionnaires offered additional variance in predicting BMI. Hence, these questionnaires seemed to characterise a common factor, which we label Uncontrolled Eating. Item Response Theory techniques were then applied to demonstrate that c) within this common factor, the questionnaires could be placed on a continuum of Uncontrolled Eating. That is, Eating Impulsivity focused on the milder degree, Power of Food Scale, emotional eating scales, and Disinhibition on intermediate degrees, and the Binge Eating Scale on the most severe degrees of Uncontrolled Eating. In sum, evidence from two samples showed that questionnaires capturing five common BMI-related traits largely reflected the same underlying latent trait - Uncontrolled Eating. In Estonia, some questionnaires focused on different severities of this common construct, supporting a continuum model of Uncontrolled Eating. These findings provide a starting point for developing better questionnaires of the neurobehavioural correlates of obesity, and provide a unifying perspective from which to view the existing literature. R scripts and data used for the analysis are provided. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Deficits in episodic memory are related to uncontrolled eating in a sample of healthy adults.

    Science.gov (United States)

    Martin, A A; Davidson, T L; McCrory, M A

    2018-05-01

    Despite a substantial amount of animal data linking deficits in memory inhibition to the development of overeating and obesity, few studies have investigated the relevance of memory inhibition to uncontrolled eating in humans. Further, although memory for recent eating has been implicated as an important contributor to satiety and energy intake, the possibility that variations in episodic memory relate to individual differences in food intake control has been largely neglected. To examine these relationships, we recruited ninety-three adult subjects to attend a single lab session where we assessed body composition, dietary intake, memory performance, and eating behaviors (Three Factor Eating Questionnaire). Episodic recall and memory inhibition were assessed using a well-established measure of memory interference (Retrieval Practice Paradigm). Hierarchical regression analyses indicated that memory inhibition was largely unrelated to participants' eating behaviors; however, episodic recall was reliably predicted by restrained vs. uncontrolled eating: recall was positively associated with strategic dieting (β = 2.45, p = 0.02), avoidance of fatty foods (β = 3.41, p = 0.004), and cognitive restraint (β = 1.55, p = 0.04). In contrast, recall was negatively associated with uncontrolled eating (β = -1.15, p = 0.03) and emotional eating (β = -2.46, p = 0.04). These findings suggest that episodic memory processing is related to uncontrolled eating in humans. The possibility that deficits in episodic memory may contribute to uncontrolled eating by disrupting memory for recent eating is discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Risk Assessment During the Final Phase of an Uncontrolled Re-Entry

    Science.gov (United States)

    Gaudel, A.; Hourtolle, C.; Goester, J. F.; Fuentes, N.

    2013-09-01

    As French National Space Agency, CNES is empowered to monitor compliance with technical regulations of the French Space Operation Act, FSOA, and to take all necessary measures to ensure the safety of people, property, public health and environment for all space operations involving French responsibility at international level.Therefore, CNES developed ELECTRA that calculates the risk for ground population involved in three types of events: rocket launching, controlled re-entry and uncontrolled re-entry. For the first two cases, ELECTRA takes into account degraded cases due to a premature stop of propulsion.Major evolutions were implemented recently on ELECTRA to meet new users' requirements, like the risk assessment during the final phase of uncontrolled re-entry, that can be combined with the computed risk for each country involved by impacts.The purpose of this paper is to provide an overview of the ELECTRA method and main functionalities, and then to highlight these recent improvements.

  15. Transfer Pricing: Is the Comparable Uncontrolled Price Method the Best Method in all Cases?

    Directory of Open Access Journals (Sweden)

    Pranvera Dalloshi

    2012-12-01

    Full Text Available The transfer price scope is becoming a very important issue for all companies that comprise from different departments or have a network of branches. These companies are obliged to present the way of price determination for transactions that they have with their branches or other relevant members of their network. The establishment of the multinational companies that develop their activities in various countries is being increased. It has increased the need to supervise their transactions and approval of laws and administrative orders that do not leave space for misuses. The paper is focused in the response to the question if the Comparable Uncontrolled Price Method is the best method to be used in all cases. It is presented through a concrete example that shows how the price of a product determined through the Comparable Uncontrolled Price Method or market price has an impact to the profit of the mother company and other subsidiaries.

  16. Relationship of left ventricular, elastic and muscular arteries remodeling in patients with uncontrolled arterial hypertension

    Directory of Open Access Journals (Sweden)

    S. Ya. Dotsenko

    2013-04-01

    Full Text Available Introduction. Uncontrolled hypertension is observed in 65-92% of hypertensive patients. It plays an important role in the development of adverse cardiovascular events and survival, which depend on subclinical target organ damage. There are reports on the relationship between ineffective hypertension control and left ventricular (LV hypertrophy or large arteries stiffness. However, the nature of the remodeling in uncontrolled hypertension remains poorly understood. Objective: to study the character and relationship of left ventricular and arterial remodeling depending on effectiveness of hypertension control. Design and method. We performed a study of 363 hypertensive patients (160 men and 203 women aged 50,8 ± 1,2 years without comorbidities, which were divided into 3 groups according to the effectiveness of blood pressure (BP control: 160 patients with controlled hypertension, 142 patients with uncontrolled hypertension and 61 patients with resistant hypertension. Uncontrolled BP based on measured systolic BP≥140 mmHg and diastolic BP≥90 mmHg. Remodeling indexes of left ventricular, elastic (common carotid and muscular (brachial artery were evaluated by the ultrasonic method. The severity and character of diastolic dysfunction, hypertrophy, types of remodeling and stiffness were assessed. Statistical processing of the results was performed using Student's t criterion and Pearson correlation analysis. Results and discussion. According to the results of the study, uncontrolled hypertension affected the development of subclinical cardiovascular lesions negatively. Thus, LV hypertrophy was detected more frequently in the third group (91,8% in resistant hypertension versus 46,8% in controlled hypertension, p<0,05. Differences in LV geometry with increasing of concentric remodeling types were also observed more frequently in the third group, where concentric remodeling and concentric hypertrophy types were founded in 14,8% and 59

  17. Bakri balloon as a uterus preserving treatment of uncontrollable haemorrhage one month post-partum

    DEFF Research Database (Denmark)

    Bonnici, Mia; Markauskas, Algirdas; Munk, Torben

    2014-01-01

    In this case Bakri balloon was used to stop haemorrhage one month post-partum. The case introduces the use of this device outside usual indications. A 27-year-old woman was admitted several times with vaginal bleeding after caesarean section. She was treated pharmacologically and with curettage. ....... One month post-partum hysteroscopic removal of placental tissue was done. During this uncontrollable haemorrhage occurred and hysterectomy was considered. An attempt to save the uterus with Bakri balloon was made succesfully....

  18. Personality and Cognitive Abilities: Predictors of Restrained, Uncontrolled and Emotional Eating Behaviours?

    OpenAIRE

    Howard, Kirstie

    2014-01-01

    Abstract The psychology of eating behaviour merits more attention, due to the increasing prevalence of eating disorders, obesity and other eating related issues. There is a need for a more grounded understanding of the behavioural, emotional and cognitive aspects of dietary habits. Aim: To examine the relationship between personality, cognitive abilities and eating behaviours; Restrained Eating (RE), Uncontrolled Eating (UE) and Emotional Eating (EE). This was based on a series of pre...

  19. Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya

    Directory of Open Access Journals (Sweden)

    Mary N. Kubo

    2015-01-01

    Full Text Available Objective. To determine the factors associated with poor blood pressure control among renal transplant recipients in a resource-limited setting. Methods. A cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital. Sociodemographic details, blood pressure, urine albumin : creatinine ratio, and adherence using the MMAS-8 questionnaire were noted. Independent factors associated with uncontrolled hypertension were determined using logistic regression analysis. Results. 85 subjects were evaluated. Mean age was 42.4 (SD ± 12.2 years, with a male : female ratio of 1.9 : 1. Fifty-five patients (64.7% had uncontrolled hypertension (BP ≥ 130/80 mmHg. On univariate analysis, male sex (OR 3.7, 95% CI 1.4–9.5, p=0.006, higher levels of proteinuria (p=0.042, and nonadherence to antihypertensives (OR 18, 95% CI 5.2–65.7, p<0.001 were associated with uncontrolled hypertension. On logistic regression analysis, male sex (adjusted OR 4.6, 95% CI 1.1–19.0, p=0.034 and nonadherence (adjusted OR 33.8, 95% CI 8.6–73.0, p<0.001 were independently associated with uncontrolled hypertension. Conclusion. Factors associated with poor blood pressure control in this cohort were male sex and nonadherence to antihypertensives. Emphasis on adherence to antihypertensive therapy must be pursued within this population.

  20. Harnessing happiness? Uncontrollable positive emotion in bipolar disorder, major depression, and healthy adults.

    Science.gov (United States)

    Kang, Yoona; Gruber, June

    2013-04-01

    The ability to adaptively exert control over negative emotions is associated with beneficial mental health outcomes. Less is known about the associated emotional sequelae surrounding controllable versus uncontrollable positive emotional experiences. The ability to harness positive emotions is of particular importance in populations involving disrupted positive emotion functioning. In the present study, participants engaged in a relived memory task in which they recalled either a controllable or uncontrollable past positive emotional experience in counterbalanced order, while concurrent experiential and autonomic responses were measured. Participants included adults with bipolar I disorder (BD; n = 32), major depression (MDD; n = 32), and or nonpsychiatric controls (CTLs; n = 31). Across all participants, reliving a controllable positive emotion experience was associated with exhibited increased respiratory sinus arrhythmia, an autonomic marker of regulatory control. Interestingly, only the MDD group reported increased positive emotion and decreased cardiovascular arousal when reliving an event involving uncontrollable positive emotion, compared to the BD and CTL groups. No other group differences emerged. These findings suggest that although controllable positive emotion experiences may be adaptive for most, individuals with a history of restricted affect and depressed mood may actually derive more pleasure from times of unharnessed happiness. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  1. Surgical Outcomes of Ahmed or Baerveldt Tube Shunt Implantation for medically Uncontrolled Traumatic Glaucoma.

    Science.gov (United States)

    Yadgarov, Arkadiy; Liu, Dan; Crane, Elliot S; Khouri, Albert S

    2017-01-01

    To describe postoperative surgical success of either Ahmed or Baerveldt tube shunt implantation for eyes with medically uncontrolled traumatic glaucoma. A review was carried out to identify patients with traumatic glaucoma that required tube shunt implantation between 2009 and 2015 at Rutgers University in Newark, New Jersey, USA. Seventeen eyes from 17 patients met inclusion criteria, including at least 3-month postoperative follow-up. The main outcome measure was surgical success at 1-year follow-up after tube implantation. Mean preoperative intraocular pressure (IOP) was 34.1 ± 8.2 mm Hg on 3.1 ± 1.6 ocular hypotensive medications. Nine eyes (53%) sustained closed globe injury. Ten eyes (59%) received an Ahmed valve shunt and seven eyes (41%) received a Baerveldt tube shunt. Surgical success rate at 1 year postoperatively was 83%. Compared to preoperative, the mean postoperative IOP was significantly lower (16.1 ± 3.5 mm Hg, p Ahmed or Baerveldt tube shunt provided successful control of IOP in patients with medically uncontrollable traumatic glaucoma. Yadgarov A, Liu D, Crane ES, Khouri AS. Surgical Outcomes of Ahmed or Baerveldt Tube Shunt Implantation for medically Uncontrolled Traumatic Glaucoma. J Curr Glaucoma Pract 2017;11(1):16-21.

  2. A review of remote sensing applications for oil palm studies

    Institute of Scientific and Technical Information of China (English)

    Khai Loong Chong; Kasturi Devi Kanniah; Christine Pohl; Kian Pang Tan

    2017-01-01

    Oil palm becomes an increasingly important source of vegetable oil for its production exceeds soybean,sunflower,and rapeseed.The growth of the oil palm industry causes degradation to the environment,especially when the expansion of plantations goes uncontrolled.Remote sensing is a useful tool to monitor the development of oil palm plantations.In order to promote the use of remote sensing in the oil palm industry to support their drive for sustainability,this paper provides an understanding toward the use of remote sensing and its applications to oil palm plantation monitoring.In addition,the existing knowledge gaps are identified and recommendations for further research are given.

  3. Remote possibilities

    International Nuclear Information System (INIS)

    Fernandes, J.

    1995-01-01

    The impact that wireless communications has had for gas and oil producers was discussed. Wireless communication, which has been replacing the traditional formats of radio and telephone data networks, has proved to be cheaper, smaller, and faster than creating privately owned communication networks. With highly developed supervisory control and data acquisition systems - combined with cellular or satellite technology - information from drill sites can be online at the corporate headquarters instantaneously. Eighty percent of Canada's land mass is beyond reach of traditional wireline and wireless services. Research into advanced communications, including telecommunication and mobile applications, yielded lucrative results for service providers such as BCTel, SaskTel, Bell Mobility and AGT. The latest data transmission technology is the cellular digital packet data (CDPD) which will operate over existing cellular networks. However, unlike circuit-switched cellular, CDPD technology provides an airlink where data is secure. It will be available to the marketplace over the course of the coming year. Among other advantages, CDPD will allow producers to remotely monitor production information and downtime alarms from wells and compressor stations. It will also provide fleet operators with the means to monitor operating vital signs on rolling stock

  4. Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension (the ROX CONTROL HTN study): a randomised controlled trial.

    LENUS (Irish Health Repository)

    Lobo, Melvin D

    2015-01-22

    Hypertension contributes to cardiovascular morbidity and mortality. We assessed the safety and efficacy of a central iliac arteriovenous anastomosis to alter the mechanical arterial properties and reduce blood pressure in patients with uncontrolled hypertension.

  5. The Role of Salivary Gland Scintigraphy in the Evaluation of Salivary Gland Dysfunction in Uncontrolled Type II Diabetic Patients

    OpenAIRE

    Senthilkumar, B.; Sathasivasubramanian, S.

    2013-01-01

    The aim of the present study was to evaluate the salivary gland dysfunction in patients with uncontrolled type II diabetes using salivary gland scintigraphy and then to compare these ratios with quantitative whole salivary secretion rates. Using a gamma camera (siemens-diacam) equipped with a low energy all-purpose collimator, 32 uncontrolled type II diabetic patients and 30 normal healthy patients were studied by injecting a radio isotope (technetium 99m pertechnetate) about 5 mCi was inject...

  6. Uncontrolled hypertension secondary to leukemic cell infiltration of kidneys in a hemodialysis patient

    Directory of Open Access Journals (Sweden)

    Kultigin Turkmen

    2010-06-01

    Full Text Available Kultigin Turkmen1, Lutfullah Altintepe2, Ibrahim Guney2, Ismet Aydogdu3, Osman Koc4, Mehmet Ali Erkut5, Halil Zeki Tonbul11Department of Nephrology, Meram School of Medicine, Selcuk University, 2Meram Training and Research Hospital, Selcuk University, 3Department of Hematology, Meram School of Medicine, Selcuk University, 4Department of Radiology, Meram School of Medicine, Selcuk University, 5Department of Hematology, Meram Training and Research Hospital, Selcuk UniversityAbstract: Leukemic infiltration of the kidney is usually silent, and the admission of the patients with renal dysfunction or acute kidney injury is uncommon. We present a 34-year old hemodialysis patient with new onset of uncontrolled hypertension, erythropoietin-resistant anemia, thrombocytopenia, and Bell’s palsy. On admission, his blood pressure (BP was 210/110 mmHg and he had petechiae and purpura at upper and lower extremities. Renal ultrasonography (USG showed bilaterally enlarged kidneys without hydronephrosis, unlike his previous USG, which determined bilaterally atrophic kidneys. Acute lymphoblastic leukemia, hypertensive crisis due to bilateral leukemic cell infiltration of kidneys, tumor lysis syndrome, and leukemic involvement of the facial nerve were diagnosed. Despite intense antihypertensive management, his BP was not controlled. After prednisolone, daunorubicine, and vincristine therapy, the size of kidneys diminished and his BP dropped under normal range. In conclusion, pathological findings such as uncontrolled hypertension, flank pain, skin rashes, and abnormal blood count should be considered carefully, even in patients with end-stage renal disease receiving renal replacement therapy.Keywords: leukemic cell infiltration, uncontrolled hypertension, hemodialysis

  7. Prevalence of Recommendations Made Within Dental Research Articles Using Uncontrolled Intervention or Observational Study Designs.

    Science.gov (United States)

    Wilson, M K; Chestnutt, I G

    2016-03-01

    Evidence to inform clinical practice is reliant on research carried out using appropriate study design. The objectives of this work were to (i) identify the prevalence of articles reporting on human studies using uncontrolled intervention or observational research designs published in peer-reviewed dental journals and (ii) determine the nature of recommendations made by these articles. Six peer-reviewed dental journals were selected. Issues published in January to June 2013 were examined and the types of articles published categorized. Following pre-defined inclusion/exclusion criteria, human studies classified as using uncontrolled intervention or observational research designs were subject to detailed review by two independent investigators, to examine if they presented clinical, policy or research recommendations and if these recommendations were supported by the data presented. 52.9% (n = 156) of studies published during the time period met the inclusion criteria. Studies with uncontrolled intervention or observational research designs comprised a larger proportion of the primary research studies published in the journals with lower impact factors (73.3%; n = 107) compared to the high impact journals (38.9%; n = 49). Analysis showed that 60.9% (n = 95) of the included studies made recommendations for clinical practice/dental policy. In 28.2% (n = 44) of studies, the clinical/policy recommendations made were judged to not be fully supported by the data presented. Many studies published in the current dental literature, which are not considered to produce strong evidence, make recommendations for clinical practice or policy. There were some cases when the recommendations were not fully supported by the data presented. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Mobile robot multi-sensor unit for unsupervised gas discrimination in uncontrolled environments

    OpenAIRE

    Xing, Yuxin; Vincent, Timothy A.; Cole, Marina; Gardner, Julian W.; Fan, Han; Hernandez Bennetts, Victor; Schaffernicht, Erik; Lilienthal, Achim

    2017-01-01

    In this work we present a novel multi-sensor unit to detect and discriminate unknown gases in uncontrolled environments. The unit includes three metal oxide (MOX) sensors with CMOS micro heaters, a plasmonic enhanced non-dispersive infra-red (NDIR) sensor, a commercial temperature humidity sensor, and a flow sensor. The proposed sensing unit was evaluated with plumes of gases (propanol, ethanol and acetone) in both, a laboratory setup on a gas testing bench and on-board a mobile robot operati...

  9. Causal Analysis of The Uncontrolled Moderator In The HFEF Main Cell

    Energy Technology Data Exchange (ETDEWEB)

    Posegate, Charles R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Crofts, Bryan P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2012-12-01

    On 11/07/2012 while investigating the cause of defects in neutron radiography film at HFEF, oil was discovered near the elevator shaft located at the 4M location within the Main Cell. Subsequent investigation identified oil (untracked moderator) in several locations ofthe HFEF Main Cell. Initial analysis determined that oil leaking from a 1M shielding window had leaked past a compensatory containment system resulting in a thin layer of oil found in several locations on the main cell floor. The result of this condition is uncontrolled moderator in moderator controlled zones, which is a violation of Criticality Hazard Control Statements (CHCS) for HFEF.

  10. Data on the oral CRTh2 antagonist QAW039 (fevipiprant in patients with uncontrolled allergic asthma

    Directory of Open Access Journals (Sweden)

    Veit J. Erpenbeck

    2016-12-01

    Full Text Available This article contains data on clinical endpoints (Peak Flow Expiratory Rate, fractional exhaled nitric oxide and total IgE serum levels and plasma pharmacokinetic parameters concerning the use of the oral CRTh2 antagonist QAW039 (fevipiprant in mild to moderate asthma patients. Information on experimental design and methods on how this data was obtained is also described. Further interpretation and discussion of this data can be found in the article “The oral CRTh2 antagonist QAW039 (fevipiprant: a phase II study in uncontrolled allergic asthma” (Erpenbeck et al., in press [1].

  11. Evidence of Human Health Impacts from Uncontrolled Coal Fires in Jharia, India

    Science.gov (United States)

    Dhar, U.; Balogun, A. H.; Finkelman, R.; Chakraborty, S.; Olanipekun, O.; Shaikh, W. A.

    2017-12-01

    Uncontrolled coal fires and burning coal waste piles have been reported from dozens of countries. These fires can be caused by spontaneous combustion, sparks from machinery, lightning strikes, grass or forest fires, or intentionally. Both underground and surface coal fires mobilize potentially toxic elements such as sulfur, arsenic, selenium, fluorine, lead, and mercury as well as dangerous organic compounds such as benzene, toluene, xylene, ethylbenzene and deadly gases such as CO2 and CO. Despite the serious health problems that can be caused by uncontrolled coal fires it is rather surprising that there has been so little research and documentation of their health impacts. Underground coal fires in the Jharia region of India where more than a million people reside, have been burning for 100 years. Numerous villages exist above the underground fires exposing the residents daily to dangerous emissions. Local residents near the fire affected areas do their daily chores without concern about the intensity of nearby fires. During winter children enjoy the heat of the coal fires oblivious to the potentially harmful emissions. To determine if these uncontrolled coal fires have caused health problems we developed a brief questionnaire on general health indices and administered it to residents of the Jharia region. Sixty responses were obtained from residents of two villages, one proximal to the coal fires and one about 5 miles away from the fires. The responses were statistically analyzed using SAS 9.4. It was observed that at a significance level of 5%, villagers who lived more than 5 miles away from the fires had a 98.3% decreased odds of having undesirable health outcomes. This brief survey indicates the risk posed by underground coal fires and how it contributes to the undesirable health impacts. What remains is to determine the specific health issues, what components of the emissions cause the health problems, and what can be done to minimize these problems

  12. Temporary balloon occlusion as therapy for uncontrollable arterial hemorrhage in multiply injured patients

    International Nuclear Information System (INIS)

    Rieger, J.; Linsenmaier, U.; Rock, C.; Pfeifer, K.J.; Euler, E.

    1999-01-01

    Purpose: Presentation of temporary balloon occlusion as an interventional radiological method for managing hemorrhage in multiply injured patients with uncontrollable loss of blood. Method: Temporary, non-selective arterial occlusion by introduction of a balloon catheter contralaterally to the source of bleeding has been performed since 1992 on 7 patients with multiple injuries, hemorrhagic shock requiring reanimation, and angiographic demonstration of an arterial hemorrhage in the supply region of the internal iliac artery with complex pelvic fracture. In each case a PTA balloon catheter was introduced transfemorally, non-selectively positioned proximal to the bleeding source, and left in place for 24-48 h under manometric control. Control angiographies were performed prior to catheter removal. Results: The bleeding was stopped immediately in all 7 patients. The hemodynamic stability made transport and thus further surgical management and/or a short-term treatment in the intensive-care station possible. Control angiographies confirmed that the bleeding had stopped in all patients. Conclusions: We recommend temporary balloon occlusion as a rapid and effective method for the management of bleeding in otherwise uncontrollable traumatic hemorrhages in the supply region of the internal iliac artery. (orig.) [de

  13. [Perception of insulin therapy in uncontrolled patients with type 2 diabetes mellitus].

    Science.gov (United States)

    Leyva Jiménez, Rafael; Hernández Zambrano, Gustavo; Ibarra Maldonado, Silvia; Ibarra Ramírez, Carlos Tomás

    2016-10-01

    To determine the perception of insulin therapy by patients with uncontrolled type2 diabetes mellitus, who have been treated with oral hypoglycaemic agents or insulin. Prospective comparative cross-sectional study. Family Medicine Unit No. 53 León, Guanajuato of Mexican Institute of Social Security. Patients between 40 and 80years old with uncontrolled type2 mellitus diabetes, treated with insulin or oral hypoglycaemic agents. Perception was assessed using the insulin treatment appraisal scale (ITAS). The rating of the survey is from 20 to 100 points, as such that when score increases the greater is the negative opinion. A sample of 459 diabetes patients were interviewed and split into 2 groups of patients according to their treatment. The OH group were patients treated with oral hypoglycaemic drugs only (56.9%), and the IN group were patients treated with insulin alone or combined with an oral hypoglycaemic (43.1%). Perception score was significantly higher in OH group (56.95±7.78 versus 49.55±8.89 points) than in the IN group (P1). The perception of insulin therapy was worse in patients treated with only oral hypoglycaemic agents than in patients using insulin. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  14. Intention-Aware Autonomous Driving Decision-Making in an Uncontrolled Intersection

    Directory of Open Access Journals (Sweden)

    Weilong Song

    2016-01-01

    Full Text Available Autonomous vehicles need to perform social accepted behaviors in complex urban scenarios including human-driven vehicles with uncertain intentions. This leads to many difficult decision-making problems, such as deciding a lane change maneuver and generating policies to pass through intersections. In this paper, we propose an intention-aware decision-making algorithm to solve this challenging problem in an uncontrolled intersection scenario. In order to consider uncertain intentions, we first develop a continuous hidden Markov model to predict both the high-level motion intention (e.g., turn right, turn left, and go straight and the low level interaction intentions (e.g., yield status for related vehicles. Then a partially observable Markov decision process (POMDP is built to model the general decision-making framework. Due to the difficulty in solving POMDP, we use proper assumptions and approximations to simplify this problem. A human-like policy generation mechanism is used to generate the possible candidates. Human-driven vehicles’ future motion model is proposed to be applied in state transition process and the intention is updated during each prediction time step. The reward function, which considers the driving safety, traffic laws, time efficiency, and so forth, is designed to calculate the optimal policy. Finally, our method is evaluated in simulation with PreScan software and a driving simulator. The experiments show that our method could lead autonomous vehicle to pass through uncontrolled intersections safely and efficiently.

  15. Omalizumab in Japanese children with severe allergic asthma uncontrolled with standard therapy.

    Science.gov (United States)

    Odajima, Hiroshi; Ebisawa, Motohiro; Nagakura, Toshikazu; Fujisawa, Takao; Akasawa, Akira; Ito, Komei; Doi, Satoru; Yamaguchi, Koichi; Katsunuma, Toshio; Kurihara, Kazuyuki; Kondo, Naomi; Sugai, Kazuko; Nambu, Mitsuhiko; Hoshioka, Akira; Yoshihara, Shigemi; Sato, Norio; Seko, Noriko; Nishima, Sankei

    2015-10-01

    Omalizumab has demonstrated clinical benefits in children with moderate to severe allergic asthma. However, no studies have been performed in Japanese asthmatic children. The aim of this study was to evaluate the efficacy including free IgE suppression and safety of omalizumab in Japanese children with severe allergic asthma. The primary objective was to examine whether omalizumab decreases serum free IgE levels to less than 25 ng/ml (target level of suppression). Thirty-eight Japanese children (6-15 years) with uncontrolled severe allergic asthma despite inhaled corticosteroids (>200 μg/day fluticasone propionate or equivalent) and two or more controller therapies received add-on treatment with omalizumab in a 24-week, multicenter, uncontrolled, open-label study. The geometric mean serum free IgE level at 24 weeks was 15.6 ng/mL. Compared with baseline, total asthma symptom scores, daily activity scores and nocturnal sleep scores at 24 weeks were significantly improved. The rates of asthma exacerbation and hospitalization due to asthma were reduced by 69.2% and 78.2%, respectively (p omalizumab decreased free IgE levels to less than 25 ng/mL. Omalizumab improved asthma control and was well-tolerated, as well. Copyright © 2015 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

  16. The medical antigravity suit for management of surgically uncontrollable bleeding associated with abdominal pregnancy.

    Science.gov (United States)

    Sandberg, E C; Pelligra, R

    1983-07-01

    Three patients with abdominal pregnancy have been treated at Stanford University Hospital in recent years. Common to each was surgically uncontrolled hemorrhage for which circumferential pneumatic compression (supplied by a medical antigravity suit) was used to stop the bleeding. In each patient, the hemostatic effect of treatment was dramatic. In published accounts of the use of the garment in other severely hemorrhaging patients, the effects have been similarly dramatic and equally successful. These observations lead to a compelling consideration in regard to optimum management of patients with abdominal pregnancy. If our experience is confirmed by others, optimum management in abdominal pregnancy hereafter should regularly and routinely include removal of the placenta at the primary operation. This approach would anticipate use of the medical antigravity suit to provide hemostasis if surgically uncontrollable bleeding is encountered. Theoretically, the complications and long-term morbidity associated with retention of the placenta would be eliminated by this means while the previous disadvantage of placental removal, the potential for exsanguinating hemorrhage, would be circumvented.

  17. Planning for the closure of uncontrolled landfills in Turkey to reduce environmental impacts.

    Science.gov (United States)

    Ergene Şentürk, Didar; Alp, Emre

    2016-11-01

    Landfilling is the most preferred solid waste disposal method in Turkey owing to both economic and technical reasons. However, beside the sanitary landfills there are also hundreds of uncontrolled waste sites located throughout Turkey, which are often left either abandoned or burning. Because there is a lack of legislative guidelines governing the closure and rehabilitation of these dumpsites, the municipalities that are responsible for waste management do not initiate the proactive strategies required for the closure of these sites. In this study, a method based on a multi-criteria analysis is conducted for different dumpsites in Turkey to evaluate the level of negative impacts on the environment. This method is based on the use of environmental indices for a quantitative assessment of the landfills, such as environmental interaction between the source and the receptors, environmental values of the receptors, and operational conditions. It was possible to assess the robustness of the proposed methodology since the pre- and post-groundwater quality monitoring data was available from the study sites that were closed and rehabilitated in 2014. The results of this study show that the method based on a multi-criteria analysis is an effective tool while in the preliminary planning stages of closure and rehabilitation activities of uncontrolled waste landfills. © The Author(s) 2016.

  18. Patient Perspectives on Quality of Life With Uncontrolled Type 1 Diabetes Mellitus: A Systematic Review and Qualitative Meta-synthesis.

    Science.gov (United States)

    Vanstone, Meredith; Rewegan, Alex; Brundisini, Francesca; Dejean, Deirdre; Giacomini, Mita

    2015-01-01

    Patients with uncontrolled type 1 diabetes mellitus may be candidates for pancreatic islet cell transplantation. This report synthesizes qualitative research on how patients with uncontrolled type 1 diabetes perceive their quality of life. The objective of this analysis was to examine the perceptions of patients with uncontrolled type 1 diabetes on how it affects their lived experience and quality of life. This report synthesizes 31 primary qualitative studies to examine quality of life from the perspectives of adult patients with type 1 diabetes mellitus and their families or partners. We performed a qualitative meta-synthesis to integrate findings across primary research studies. Long- and short-term negative consequences of uncontrolled type 1 diabetes affect all aspects of patients' lives: physical, emotional, practical, and social. The effect on each domain is far-reaching, and effects interact across domains. Uncontrolled blood sugar levels lead to substantial psychological distress, negative moods, cognitive difficulties, irritable or aggressive behaviour, and closely associated problems with relationships, self-image, and confidence. Emotional distress is pervasive and under-addressed by health care providers. Patients live in fear of complications from diabetes over the long term. In the shorter term, they are anxious about the personal, social, and professional consequences of hypoglycemic episodes (e.g., injury, humiliation), and may curtail normal activities such as driving or socializing because they are worried about having an episode. The quality of life for patients' family members is also negatively impacted by uncontrolled type 1 diabetes. Uncontrolled type 1 diabetes has significant negative impacts on the quality of life of both people with the disease and their families.

  19. DESIGNING ZONING OF REMOTE SENSING DRONES FOR URBAN APPLICATIONS: A REVIEW

    OpenAIRE

    M. N. Norzailawati; A. Alias; R. S. Akma

    2016-01-01

    This paper discusses on-going research related to zoning regulation for the remote sensing drone in the urban applications. Timestamped maps are presented here follow a citation-based approach, where significant information is retrieved from the scientific literature. The emergence of drones in domestic air raises lots understandable issues on privacy, security and uncontrolled pervasive surveillance that require a careful and alternative solution. The effective solution is to adopt ...

  20. Uncontrolled Hypertension and Its Determinants in Patients with Concomitant Type 2 Diabetes Mellitus (T2DM in Rural South Africa.

    Directory of Open Access Journals (Sweden)

    Oladele Vincent Adeniyi

    Full Text Available Paucity of data on the prevalence, treatment and control of hypertension in individuals living with type 2 diabetes mellitus (T2DM in the rural communities of South Africa may undermine efforts to reduce the morbidity and mortality associated with cardiovascular diseases. This study examines the socio-demographic and clinical determinants of uncontrolled hypertension among individuals living with T2DM in the rural communities of Mthatha, South Africa.This cross-sectional study involved a serially selected sample of 265 individuals living with T2DM and hypertension at Mthatha General Hospital, Mthatha. Uncontrolled hypertension was defined as systolic blood pressure greater than or equal to 140 mmHg and diastolic blood pressure greater than or equal to 90mmHg in accordance with the Eight Joint National Committee Report (JNC 8 (2014. We performed univariate and multivariate logistic regression analyses to identify the significant determinants of uncontrolled hypertension.Of the total participants (n = 265, the prevalence of uncontrolled hypertension was 75.5% (n = 200. In univariate analysis of all participants, male gender (p = 0.029, age≥65 years (p = 0.016, unemployed status (p<0.0001, excessive alcohol intake (p = 0.005 and consumption of western-type diet (p<0.0001 were positively associated with uncontrolled hypertension. In multivariate logistic regression (LR method analysis, unemployed status (p<0.0001, excessive alcohol intake (p = 0.007 and consumption of western-type diet (p<0.0001 were independently and significantly associated with uncontrolled hypertension. There is significant association between increasing number and classes of anti-hypertensive drugs and uncontrolled hypertension (p = 0.05 and 0.02, respectively.Prevalence of uncontrolled hypertension was high in individuals with concomitant hypertension and T2DM in the study population. Male sex, aging, clinic inertia, unemployed status and nutritional transitions are the most

  1. Glycated hemoglobin correlates with arterial stiffness and endothelial dysfunction in patients with resistant hypertension and uncontrolled diabetes mellitus.

    Science.gov (United States)

    Moreno, Beatriz; de Faria, Ana Paula; Ritter, Alessandra Mileni Versuti; Yugar, Lara Buonalumi Tacito; Ferreira-Melo, Silvia Elaine; Amorim, Rivadavio; Modolo, Rodrigo; Fattori, André; Yugar-Toledo, Juan Carlos; Coca, Antonio; Moreno, Heitor

    2018-05-01

    This study aimed to evaluate the effects of glycated hemoglobin (HbA 1c ) on flow-mediated dilation, intima-media thickness, pulse wave velocity, and left ventricular mass index in patients with resistant hypertension (RHTN) comparing RHTN-controlled diabetes mellitus and RHTN-uncontrolled type 2 diabetes mellitus. Two groups were formed: HbA 1c diabetes mellitus: n = 98) and HbA 1c ≥7.0% (RHTN-uncontrolled diabetes mellitus: n = 122). Intima-media thickness and flow-mediated dilation were measured by high-resolution ultrasound, left ventricular mass index by echocardiography, and arterial stiffness by carotid-femoral pulse wave velocity. No differences in blood pressure levels were found between the groups but body mass index was higher in patients with RHTN-uncontrolled diabetes mellitus. Endothelial dysfunction and arterial stiffness were worse in patients with RHTN-uncontrolled diabetes mellitus. Intima-media thickness and left ventricular mass index measurements were similar between the groups. After adjustments, multiple linear regression analyses showed that HbA 1c was an independent predictor of flow-mediated dilation and pulse wave velocity in all patients with RHTN. In conclusion, HbA 1c may predict the grade of arterial stiffness and endothelial dysfunction in patients with RHTN, and superimposed uncontrolled diabetes mellitus implicates further impairment of vascular function. ©2018 Wiley Periodicals, Inc.

  2. Emotional and uncontrolled eating styles and chocolate chip cookie consumption. A controlled trial of the effects of positive mood enhancement.

    Science.gov (United States)

    Turner, Sally Ann; Luszczynska, Aleksandra; Warner, Lisa; Schwarzer, Ralf

    2010-02-01

    The study tested the effects of positive mood enhancement on chocolate chip cookie consumption in the context of emotional and uncontrolled eating styles. The relationship between emotional eating style and chocolate chip cookie intake was assumed to be mediated by uncontrolled eating style. Further, it was hypothesized that the effectiveness of the positive mood enhancement may be more salient among those who have effective control of their eating. In this experimental study, respondents (N=106, 70% women, aged 16-45 years old) were assigned by means of cluster randomization to the control or positive mood enhancement condition (a comedy movie clip). Compared to the control condition, positive mood enhancement resulted in consuming on average 53.86 kcal less. Relationships between emotional eating style and cookie intake were mediated by uncontrolled eating. Moderated mediation analysis indicated that the effect of a mediator (uncontrolled eating) on cookie intake was moderated by the group assignment. Positive mood enhancement resulted in eating on average 3.3 cookies less among individuals with a more controlled eating style. By contrast, among those who presented uncontrolled eating, positive mood enhancement led to consuming an average of 1.7 cookies more. 2009 Elsevier Ltd. All rights reserved.

  3. Remote Network Access (RNA)

    National Research Council Canada - National Science Library

    2002-01-01

    .... Remote Network Access (RNA) includes or is associated with all communication devices/software, firewalls, intrusion detection systems and virus protection applications to ensure security of the OIG, DoD, Network from remote...

  4. Real-life efficacy and safety of omalizumab in Portuguese patients with persistent uncontrolled asthma.

    Science.gov (United States)

    Pereira Barbosa, M; Bugalho de Almeida, A; Pereira, C; Chen, C-W; Georgiou, P; Peachey, G

    2015-01-01

    The real life effectiveness, safety and the use of omalizumab for Portuguese patients with uncontrolled persistent allergic asthma are not sufficiently well known. The objective of this report was to make an evaluation, in a post-marketing, non-interventional, observational registry, of the Portuguese population included in the eXpeRience study. The methods used in this report are the same as the global eXpeRience ones, applied to a Portuguese sub-population. Patients with uncontrolled allergic asthma who had started omalizumab within the previous 15 weeks were enrolled and received omalizumab add-on therapy for 24 months. The physicians' global evaluation of treatment effectiveness (GETE), asthma symptoms and control (ACT score), quality of life (mini-AQLQ score), exacerbations, and serious adverse events (SAE) were reported. Of the 943 patients recruited in the eXpeRience registry, 62 patients were from Portugal. 62.1% of them were observed to be responders with good/excellent GETE assessment at Week 16. Clinically meaningful improvements in asthma control (ACT score) and quality of life (mini-AQLQ score) were observed with omalizumab therapy at Months 12 (mean change: +7.7 [n=35]; +2.1 [n=20], respectively) and 24 (mean change: +7.0 [n=26]; +2.7 [n=13], respectively). Asthma symptoms and rescue medication usage were reduced to ≤1 day/week at Month 24 from a baseline of ≥3.5 days/week. The proportion of patients with no clinically significant exacerbations increased from 6.5% during pre-treatment (n=62) to 50% at Month 12 (n=54) and 60% at Month 24 (n=45). The findings from the Portugal subpopulation of eXpeRience registry confirm that omalizumab add-on therapy is efficacious and well tolerated in the management of uncontrolled persistent allergic asthma. Another pertinent issue is the fact that the Portuguese subpopulation response is similar to the international population average of the study. Copyright © 2014 Sociedade Portuguesa de Pneumologia

  5. [Cardiovascular risk profile of uncontrolled hypertensive patients. The Control-Project study].

    Science.gov (United States)

    Márquez-Contreras, Emilio; Coca, Antonio; de la Figuera von Wichmann, Mariano; Divisón, Juan Antonio; Llisterri, José Luis; Sobrino, Javier; Filozof, Claudia; Sánchez-Zamorano, Miguel Angel; Grigorian Shamagian, Lilian

    2007-01-27

    To assess absolute cardiovascular risk and co-morbidities in uncontrolled hypertensive patients (blood pressure [BP]>or=140/90 mmHg or>or=130/80 mmHg in diabetics) attending Primary Care Physicians in Spain, and to determine the attitudes of these physicians towards this problem. Cross-sectional, multicenter study involving 356 general practitioners around Spain. Absolute cardiovascular risk was assessed according to ESH-ESC 2003 Guidelines in a sample of 1,710 patients. Two hundred ninety seven patients were excluded by several reasons and a total of 1,413 hypertensive patients were valuable (mean age: 65.3+/-11.4 years; 56.7% women). Normal BP values (or=180/110 mmHg) by 7.9%. Associated cardiovascular risk factors were observed in 96.0% of patients (95% CI=94.7-97.2%), target organ damage in 34.5% (95% CI=31.6-36.5%), and cardiovascular clinical disease in 36.0% (95% CI=33.5-38.5%). According to ESH-ESC 2003 Guidelines 34.0% (CI=31.5-38.2%) were at very-high risk; 29.4% (95% CI=26.4-32.8%) at high risk; 30.4% (95% CI=27.2-33.7%) at moderate risk and 5.4% (95% CI=3.9-7.2%) at low risk of cardiovascular disease. Despite the high absolute risk, physicians did not do any therapeutic change in 30.4% (95% CI=28.2-33.5%) of uncontrolled hypertensive patients. Most of them (64.26%) considered that bad compliance to life style changes was the reason for inadequate BP control. The most frequent measure introduced was the association of additional drugs. Absolute cardiovascular risk in uncontrolled hypertensive patients attending Primary Care Physicians in Spain is very relevant. Sixty-five percent of these patients are at high or very high risk with a high prevalence of target organ damage or associated cardiovascular clinical disease. Therapeutic attitudes towards these patients are still very conservative although they are improving compared with previous studies.

  6. The Uncontrolled Economic Engine of the Developing Economies, Speeding up the Climate Shift

    Science.gov (United States)

    Khan, K. M.; Khan, M. A.

    2014-12-01

    As we progress into the 21st century, the world faces challenges of truly global nature bearing implications on the whole world in one way or another. The global economic engine has shifted from the western world (Developed Economies) to the eastern world (Developing Economies) which has brought about tremendous change in the climate related variables in this part of the world. As uncontrolled carbon emissions grow in the developing economies, the phenomenon of global warming and climate shifts become more and more prevalent. While this economic activity provides income for millions of households, it is contributing generously to the rapid degradation of the environment. Developing economies as it has been seen do not employ or abide by stringent regulations regarding emissions which result in uncontrolled emissions. In this particular scenario, it is a tedious task to convince governments in the developing economies to implement regulations regarding emissions because businesses in these economies deem such regulations to be economically unviable. The other side of the problem is that these uncontrolled emission are causing evident climate shifts which has had adverse impacts on the agricultural societies where shifting climates are leading to reduced agricultural output and productivity. Consequently the lives of millions associated directly or indirectly with agriculture are affected and on a more global level, the agricultural produce is decreasing which increases the chances of famine in parts of the world. The situation could have devastating impacts on the global economy and environmental standards and therefore needs to be addressed on emergency basis. The first step towards betterment could be the introduction of the carbon trading economy in the developing economies which would incentivize emission reduction and become more attractive and in the process sustaining minimum possible damage to the environment. Though carbon trading is a formidable first step

  7. Introduction to remote sensing

    CERN Document Server

    Cracknell, Arthur P

    2007-01-01

    Addressing the need for updated information in remote sensing, Introduction to Remote Sensing, Second Edition provides a full and authoritative introduction for scientists who need to know the scope, potential, and limitations in the field. The authors discuss the physical principles of common remote sensing systems and examine the processing, interpretation, and applications of data. This new edition features updated and expanded material, including greater coverage of applications from across earth, environmental, atmospheric, and oceanographic sciences. Illustrated with remotely sensed colo

  8. Remote detection system

    International Nuclear Information System (INIS)

    Nixon, K.V.; France, S.W.; Garcia, C.; Hastings, R.D.

    1981-05-01

    A newly designed remote detection system has been developed at Los Alamos that allows the collection of high-resolution gamma-ray spectra and neutron data from a remote location. The system consists of the remote unit and a command unit. The remote unit collects data in a potentially hostile environment while the operator controls the unit by either radio or wire link from a safe position. Both units are battery powered and are housed in metal carrying cases

  9. Effectiveness of exercise at workplace in physical fitness: uncontrolled randomized study.

    Science.gov (United States)

    Grande, Antônio José; Silva, Valter; Parra, Sérgio Alencar

    2014-01-01

    To investigate the effectiveness of workplace exercise for employee health by means of health-related physical activity components. A randomized uncontrolled study with 20 workers was carried out during three months to evaluate a workplace exercise program. The selected outcomes were flexibility, body mass, fat percentage, lean mass, blood pressure, and heart rate. For statistical analysis, the paired t test and the intent-to-treat analysis were used. There was a significant increase in weight, fat percentage, blood pressure, and heart rate. However the clinical significance was 10% in the size of the effect. The changes verified in the outcomes analyzed were not significant; the variables are within normality ranges proposed by academic organizations.

  10. Acute Abdomen Due to Uncontrolled Use of Warfarin: Spontaneous Intra-abdominal

    Directory of Open Access Journals (Sweden)

    Fatih Dal

    2017-12-01

    Full Text Available Warfarin is an oral anticoagulant, which is commonly used in the treatment and prophylaxis of thromboembolic conditions. Bleeding is the primary adverse effect associated with warfarin. The majority of warfarin-related bleedings are spontaneous minor hemorrhages occurring in the subcutaneous or intramuscular tissues and can be treated by decreasing the dose of oral anticoagulants. However, although rare, it is possible to encounter spontaneous major bleedings with increased risk of mortality. Conservative approach is the preferred initial therapy for hemodynamically stable patients with major intra-abdominal hemorrhages that we define as the intermediate group patients. Nevertheless, surgery is required for hemodynamically unstable patients with acute abdominal pain in cases of ongoing active hemorrhage, generalized peritonitis, obstruction, acute abdomen, intestinal ischemia, and perforation. In this article, we present a rare case of acute abdomen and spontaneous intra-abdominal hemorrhage resulting from uncontrolled use of warfarin and a new classification requirement.

  11. Narraciones de Cien Años de Soledad Acerca del Conflicto Armado y la Violencia Política en Colombia (Naratives of One Hundred Years of Solitude About the Armed Conflict and Political Violence in Colombia

    Directory of Open Access Journals (Sweden)

    Camilo Eduardo Umaña Hernández

    2014-12-01

    Full Text Available This paper intends to explore the narrations of the conflict and political violence embedded in the novel One hundred years of solitude by Gabriel Garcia Marquez. As one of the most important Colombian books of the last century, “One Hundred years of Solitude” evidences the magical narrative and imagination of the Caribbean as well as the reality of life, death, family, love, work, social conflicts and other aspects that are relevant for understanding and exploring the perceptions of justice of a certain society. After a brief recount of certain relevant descriptions of the novel, this essay proposes the analysis of these narrations focusing in the narrations of violence and of the Colombian armed conflict in the novel. El presente artículo explora y analiza las narraciones del conflicto y la violencia política en Colombia inmersas en Cien años de soledad de Gabriel García Márquez. Como uno de los más destacados libros colombianos del último siglo, esta novela propone una narración que se desliza en un vaivén de magia e imaginación, tanto como de realidad. Un vaivén de vida y muerte, que transita por la familia, el amor, el trabajo, los conflictos sociales y otros tantos ingredientes fundamentales para entender y explorar las percepciones de justicia de una cierta sociedad. Después de hacer un recuento breve de las narraciones del libro, a través del análisis de estos relatos, el presente trabajo reflexiona sobre diferentes aspectos de la realidad colombiana inmersos en la novela, concentrándose en las narraciones de violencia política y del conflicto armado en Colombia.DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2526668

  12. The efficacy of viscocanalostomy for uncontrollable primary open-angle glaucoma in a developing country

    Directory of Open Access Journals (Sweden)

    Khodadad Moradian

    2013-01-01

    Full Text Available Purpose: To evaluate the safety and efficacy of viscocanalostomy in the management of medically uncontrollable primary open-angle glaucoma (POAG in a developing country. Materials and Methods: This is a prospective, non-randomized case series of 14 consecutive eyes with medically uncontrollable POAG, all subjected to viscocanalostomy. The main outcome measure was success rate based on the intraocular pressure (IOP level achieved post-operatively. The procedure was considered a complete success if IOP was less than 21 mmHg without any anti-glaucoma medication. Qualified success was defined as IOP of less than 21 mmHg with anti-glaucoma medication. All patients had a regular follow-up of at least 12 months. Results: IOP was reduced from a mean baseline value of 27.9 ± 7.3 mmHg (range: 21-40 mmHg to a mean final value of 16.0 ± 2.7 mmHg (range: 13-22 mmHg, which was statistically highly significant (P < 0.005. The mean number of pre-operative anti-glaucoma medications was 3.0 ± 0.4 (range: 2-4, which was reduced significantly (P < 0.0001 to 0.3 ± 0.6 (range: 0-2 at the last follow-up visit. One year post-operatively, complete success was achieved in 71% and qualified success was observed in 21.4% of patients, summing up to an overall success rate of 92.4%. There were no major complications in any of the patients. Conclusion: Viscocanalostomy could be performed effectively and safely for control of POAG in developing countries.

  13. Rescue pre-operative treatment with Lugol's solution in uncontrolled Graves' disease.

    Science.gov (United States)

    Calissendorff, Jan; Falhammar, Henrik

    2017-05-01

    Graves' disease is a common cause of hyperthyroidism. Three therapies have been used for decades: pharmacologic therapy, surgery and radioiodine. In case of adverse events, especially agranulocytosis or hepatotoxicity, pre-treatment with Lugol's solution containing iodine/potassium iodide to induce euthyroidism before surgery could be advocated, but this has rarely been reported. All patients hospitalised due to uncontrolled hyperthyroidism at the Karolinska University Hospital 2005-2015 and treated with Lugol's solution were included. All electronic files were carefully reviewed manually, with focus on the cause of treatment and admission, demographic data, and effects of iodine on thyroid hormone levels and pulse frequency. Twenty-seven patients were included. Lugol's solution had been chosen due to agranulocytosis in 9 (33%), hepatotoxicity in 2 (7%), other side effects in 11 (41%) and poor adherence to medication in 5 (19%). Levels of free T4, free T3 and heart rate decreased significantly after 5-9 days of iodine therapy (free T4 53-20 pmol/L, P  = 0.0002; free T3 20-6.5 pmol/L, P  = 0.04; heart rate 87-76 beats/min P  = 0.0007), whereas TSH remained unchanged. Side effects were noted in 4 (15%) (rash n  = 2, rash and vomiting n  = 1, swelling of fingers n  = 1). Thyroidectomy was performed in 26 patients (96%) and one was treated with radioiodine; all treatments were without serious complications. Treatment of uncontrolled hyperthyroidism with Lugol's solution before definitive treatment is safe and it decreases thyroid hormone levels and heart rate. Side effects were limited. Lugol's solution could be recommended pre-operatively in Graves' disease with failed medical treatment, especially if side effects to anti-thyroid drugs have occurred. © 2017 The authors.

  14. Evaluation of the contamination risk by 241AM from lightning rods disposed at uncontrolled garbage dump

    International Nuclear Information System (INIS)

    Marumo, Julio Takehiro

    2006-01-01

    Radioactive lightning rods were manufactured in Brazil until 1989, when the licenses for using radioactive sources in these products were lifted by the national nuclear authority. Since then, radioactive devices have been replaced by Franklin type one and collected as radioactive waste. However, only 23 percent of the estimated total number of installed rods was delivered to Brazilian Nuclear Commission (Comissao Nacional de Energia Nuclear - CNEN). This situation is of concern as there is a possibility of the rods being discarded as domestic waste, considering that in Brazil, 63.6 percent of the municipal solid waste is disposed at uncontrolled garbage dump, according to Instituto Brasileiro de Geografia e Estatistica (IBGE) in 2000. In addition, americium, the most common employed radionuclide, is classified as a high toxicity element, when ingested or inhaled. In the present study, it was performed migration experiments of Am-241 by lysimeter system in order to evaluate the risk of contamination caused by radioactive lightning rods disposed as a common solid waste. Sources removed from lightning rods were placed inside lysimeters filled with organic waste, collected at the restaurant of Instituto de Pesquisas Energeticas e Nucleares, IPEN-CNEN/SP, and the generated leachate was periodically analyzed to determine its characteristics such as pH, redox potential, solid content and concentration of the radioactive material. Microbial growth was also evaluated by counting the number of colony forming units. The equivalent dose to members of the public has been calculated considering the ingestion of drinking water, the most probable mode of exposure. The final result was about 145 times below the effective dose limit of 1 mSv.year-1 for members of the public, established by the International Commission on Radiological Protection (ICRP), demonstrating that the risk caused by lightning rods disposed at uncontrolled garbage dump is low. (author)

  15. Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension.

    Science.gov (United States)

    de la Sierra, Alejandro; Armario, Pedro; Oliveras, Anna; Banegas, José R; Gorostidi, Manuel; Vinyoles, Ernest; de la Cruz, Juan J; Segura, Julián; Ruilope, Luis M

    2018-07-01

    Treatment-resistant hypertension (TRH) is associated with particular clinical features, nonadherence, and suboptimal treatment. We assessed possible associations of antihypertensive drug classes, specific agents inside each class, and types of combinations, with the presence of non-TRH vs. TRH, and with controlled vs. uncontrolled TRH. Comparisons were done in 14 264 patients treated with three drugs (non-TRH: 2988; TRH: 11 276) and in 6974 treated with at least four drugs (controlled TRH: 1383; uncontrolled TRH: 5591). Associations were adjusted for age, sex, and previous cardiovascular event. In both groups of patients treated with three or with at least four drugs, aldosterone antagonists among drug classes [adjusted odds ratio (OR): 1.82 and 1.41, respectively], and ramipril (OR: 1.28 and 1.30), olmesartan (OR: 1.31 and 1.37), and amlodipine (OR: 1.11 and 1.41) inside each class were significantly associated with blood pressure control (non-TRH or controlled TRH). In patients treated with three drugs, non-TRH was also associated with the use of chlorthalidone (OR: 1.50) and bisoprolol (OR: 1.19), whereas in patients treated with at least four drugs, controlled TRH was significantly associated with the triple combination of a renin-angiotensin system blocker, a calcium channel blocker, and a diuretic (OR: 1.17). The use of aldosterone antagonists is associated with blood pressure control in patients treated with three or more drugs. Similar results are observed with specific agents inside each class, being ramipril, olmesartan, chlorthalidone, amlodipine, and bisoprolol those exhibiting significant results. An increased use of these drugs might probably reduce the burden of TRH.

  16. Frequency of hypomagnesemia in patients with uncontrolled type II diabetes mellitus

    International Nuclear Information System (INIS)

    Siddiqui, M.U.; Ali, I.; Asghar, S.P.; Ahmed, M.R.

    2016-01-01

    Objective: The objective of this study was to determine the frequency of Hypomagnesemia in patients with uncontrolled type II diabetes mellitus. Study Design: Cross-sectional study. Place and Duration of Study: Department of Medicine, PNS Shifa Naval Hospital Karachi, from Jul 2012 to Dec 2012 over a period of six months. Material and Methods: In this study, three hundred and twenty three patients of uncontrolled diabetes mellitus type-II on oral hypoglycemic agents for more than five years, presenting to medical OPD, were recruited. All patients fulfilled inclusion and exclusion criteria. Blood samples of all patients for serum HbA1c and serum magnesium levels were analyzed at the time of enrollment. Statistical analysis was done on SPSS 20. Results: Out of 323 patients, 243 (75.23 percent) were males and 80 (24.76 percent) were females with the age ranging from 40 - 65 years (mean age and SD 54.76 +- 6.43). Hypomagnesemia was found in 117 patients, without any significant difference in men and women (38.45 percent and 35.39 percent respectively). The mean duration of diabetes was 12.5 years (ranging from 5 to 22 years). By frequency test in SPSS-20, the highest frequency of hypomagnesemia (49.42 percent) is seen in (8.6-9.0) HbA1c group while lowest frequency hypomagnesemia (15.38 percent) is seen in (>10.0) HbA1c level group mean standard deviation and p-value calculated by Pearson correlation statistic in SPSS-20 for quantitative variables (HbA1c, Magnesium level). Conclusion: Hypomagnesemia is frequent in poorly controlled type-II diabetes mellitus having increased level of HbA1c. So it may be prudent in clinical practice to periodically monitor plasma magnesium and HbA1c in type-II diabetes mellitus patients. (author)

  17. Potential early predictors for outcomes of experimental hemorrhagic shock induced by uncontrolled internal bleeding in rats.

    Directory of Open Access Journals (Sweden)

    Zaid A Abassi

    Full Text Available Uncontrolled hemorrhage, resulting from traumatic injuries, continues to be the leading cause of death in civilian and military environments. Hemorrhagic deaths usually occur within the first 6 hours of admission to hospital; therefore, early prehospital identification of patients who are at risk for developing shock may improve survival. The aims of the current study were: 1. To establish and characterize a unique model of uncontrolled internal hemorrhage induced by massive renal injury (MRI, of different degrees (20-35% unilateral nephrectomy in rats, 2. To identify early biomarkers those best predict the outcome of severe internal hemorrhage. For this purpose, male Sprague Dawley rats were anesthetized and cannulas were inserted into the trachea and carotid artery. After abdominal laparotomy, the lower pole of the kidney was excised. During 120 minutes, hematocrit, pO2, pCO2, base excess, potassium, lactate and glucose were measured from blood samples, and mean arterial pressure (MAP was measured through arterial tracing. After 120 minutes, blood loss was determined. Statistical prediction models of mortality and amount of blood loss were performed. In this model, the lowest blood loss and mortality rate were observed in the group with 20% nephrectomy. Escalation of the extent of nephrectomy to 25% and 30% significantly increased blood loss and mortality rate. Two phases of hemodynamic and biochemical response to MRI were noticed: the primary phase, occurring during the first 15 minutes after injury, and the secondary phase, beginning 30 minutes after the induction of bleeding. A Significant correlation between early blood loss and mean arterial pressure (MAP decrements and survival were noted. Our data also indicate that prediction of outcome was attainable in the very early stages of blood loss, over the first 15 minutes after the injury, and that blood loss and MAP were the strongest predictors of mortality.

  18. Rescue pre-operative treatment with Lugol’s solution in uncontrolled Graves’ disease

    Directory of Open Access Journals (Sweden)

    Jan Calissendorff

    2017-04-01

    Full Text Available Background: Graves’ disease is a common cause of hyperthyroidism. Three therapies have been used for decades: pharmacologic therapy, surgery and radioiodine. In case of adverse events, especially agranulocytosis or hepatotoxicity, pre-treatment with Lugol’s solution containing iodine/potassium iodide to induce euthyroidism before surgery could be advocated, but this has rarely been reported. Methods: All patients hospitalised due to uncontrolled hyperthyroidism at the Karolinska University Hospital 2005–2015 and treated with Lugol’s solution were included. All electronic files were carefully reviewed manually, with focus on the cause of treatment and admission, demographic data, and effects of iodine on thyroid hormone levels and pulse frequency. Results: Twenty-seven patients were included. Lugol’s solution had been chosen due to agranulocytosis in 9 (33%, hepatotoxicity in 2 (7%, other side effects in 11 (41% and poor adherence to medication in 5 (19%. Levels of free T4, free T3 and heart rate decreased significantly after 5–9 days of iodine therapy (free T4 53–20 pmol/L, P = 0.0002; free T3 20–6.5 pmol/L, P = 0.04; heart rate 87–76 beats/min P = 0.0007, whereas TSH remained unchanged. Side effects were noted in 4 (15% (rash n = 2, rash and vomiting n = 1, swelling of fingers n = 1. Thyroidectomy was performed in 26 patients (96% and one was treated with radioiodine; all treatments were without serious complications. Conclusion: Treatment of uncontrolled hyperthyroidism with Lugol’s solution before definitive treatment is safe and it decreases thyroid hormone levels and heart rate. Side effects were limited. Lugol’s solution could be recommended pre-operatively in Graves’ disease with failed medical treatment, especially if side effects to anti-thyroid drugs have occurred.

  19. A new method for the evacuation of aqueous humor in uncontrolled glaucoma. The vitreo-tenonian tube.

    Science.gov (United States)

    Haut, J; Larricart, P; Le Mer, Y; Abboud, E

    1987-02-01

    The vitreo-tenonian tube is a new procedure, used in uncontrolled glaucoma, for the drainage of aqueous humor. It presents three original characteristics: it is made of a stainless metal, it is implanted in the posterior segment after vitrectomy and it drains the aqueous humor in the subtenonian space. We will describe first the surgical technique for the implantation of the tube, and then we will present the results of the first eight cases treated by this method. The advantages and drawbacks of this type of drainage are discussed: they are compared with the other surgical techniques used in cases of glaucoma which is uncontrolled by the classical methods.

  20. Remote Monitoring Transparency Program

    International Nuclear Information System (INIS)

    Sukhoruchkin, V.K.; Shmelev, V.M.; Roumiantsev, A.N.

    1996-01-01

    The objective of the Remote Monitoring Transparency Program is to evaluate and demonstrate the use of remote monitoring technologies to advance nonproliferation and transparency efforts that are currently being developed by Russia and the United States without compromising the national security to the participating parties. Under a lab-to-lab transparency contract between Sandia National Laboratories (SNL) and the Kurchatov Institute (KI RRC), the Kurchatov Institute will analyze technical and procedural aspects of the application of remote monitoring as a transparency measure to monitor inventories of direct- use HEU and plutonium (e.g., material recovered from dismantled nuclear weapons). A goal of this program is to assist a broad range of political and technical experts in learning more about remote monitoring technologies that could be used to implement nonproliferation, arms control, and other security and confidence building measures. Specifically, this program will: (1) begin integrating Russian technologies into remote monitoring systems; (2) develop remote monitoring procedures that will assist in the application of remote monitoring techniques to monitor inventories of HEU and Pu from dismantled nuclear weapons; and (3) conduct a workshop to review remote monitoring fundamentals, demonstrate an integrated US/Russian remote monitoring system, and discuss the impacts that remote monitoring will have on the national security of participating countries

  1. Comparative study of early liquid resuscitation in controlled and uncontrolled hemorrhagic shock

    Directory of Open Access Journals (Sweden)

    He-ming YANG

    2012-01-01

    Full Text Available Objective  To compare the effects of routine liquid resuscitation on hemorrhagic shock in uncontrolled and controlled states for exploring the strategy of liquid resuscitation. Methods  Twenty-eight healthy male SD rats were randomly divided into three groups: control (n=8, controlled hemorrhagic shock (CHS, n=10, and uncontrolled hemorrhagic shock (UHS, n=10. In the CHS and UHS groups, the rats were made to bleed from the femoral artery till the blood pressure declined to 30 mmHg within 15 minutes. Thereafter, the roots of the rat tails in the three groups were cut. The trunks of the tails were ligated to stop the bleeding in the control and CHS groups, but it was not ligated in the UHS group, and no treatment was given. Imitating war condition, the animals were divided into three phases: pre-hospital period (30–90 minutes, hospital period (90–150 minutes, and recovery period (150 minutes to 72 hours. The blood pressure was maintained at 60mmHg in the pre-hospital period by transfusion. The bleeding point was ligated in the hospital period, and the blood pressure was maintained at 90mmHg by blood and fluid transfusions. In the recovery period, the observation time was maintained up to 72 hours. The mean arterial pressure (MAP, central venous pressure (CVP, heart function, blood gas analysis, hematocrit, and blood lactic acid were determined. The amount of bleeding, quantity of infusions, and survival time of animals were observed and recorded. Results  Based on the design of the experiment, the MAP of rats in the CHS and UHS groups was maintained at 60mmHg and 90mmHg in the pre-hospital period and hospital period by liquid resuscitation, respectively. There was no significant difference in the MAP and CVP between the CHS and UHS groups. However, the hematocrit of the rats in the UHS group in the pre-hospital period was clearly lower than that in the CHS group. Starting from the pre-hospital period, blood lactic acid content increased

  2. Speech-in-noise screening tests by internet, part 3: test sensitivity for uncontrolled parameters in domestic usage

    NARCIS (Netherlands)

    Leensen, Monique C. J.; Dreschler, Wouter A.

    2013-01-01

    The online speech-in-noise test 'Earcheck' is sensitive for noise-induced hearing loss (NIHL). This study investigates effects of uncontrollable parameters in domestic self-screening, such as presentation level and transducer type, on speech reception thresholds (SRTs) obtained with Earcheck.

  3. Physical and chemical characteristics of the longissimus dorsi from swine reared in climate-controlled and uncontrolled environments

    Science.gov (United States)

    de Mello, Juliana Lolli Malagoli; Berton, Mariana Piatto; de Cassia Dourado, Rita; Giampietro-Ganeco, Aline; de Souza, Rodrigo Alves; Ferrari, Fábio Borba; de Souza, Pedro Alves; Borba, Hirasilva

    2017-10-01

    The aim of this study was to evaluate the effect of ambient temperature on the physical and chemical characteristics of the longissimus dorsi muscle by comparing the quality of meat from pigs reared in a controlled and in an uncontrolled environment, the latter provided with a shallow pool. Twenty castrated male pigs of the Topigs line were randomly allotted to two treatments: a controlled environment, with constant temperature (22 °C) and relative humidity (70%); and an uncontrolled environment in a conventional shed for rearing pigs equipped with a shallow pool, where pigs were subject to climatic variations. Meat from pigs kept in the controlled environment showed a greater capacity to retain intracellular water, higher tenderness, and lower cholesterol levels than meat from pigs reared in the uncontrolled environment, but displayed higher lipid oxidation and a lower concentration of DHA. Treatments had no effect on color, pH, chemical composition, or fatty acid profile (except DHA concentration). Rearing pigs in sheds equipped with a shallow pool minimizes the effects of environmental heat on meat quality, allowing the production of high-quality meat in warm climate regions without expensive investments. Animals reared in an uncontrolled environment equipped with a shallow pool are able to produce meat with characteristics within the quality standards and with similar quality to that of meat from animals raised in controlled environment.

  4. Where is the greatest impact of uncontrolled HIV infection on AIDS and non-AIDS events in HIV?

    NARCIS (Netherlands)

    Mocroft, Amanda; Laut, Kamilla; Reiss, Peter; Gatell, Jose; Ormaasen, Vidar; Cavassini, Matthias; Hadziosmanovic, Vesna; Mansinho, Kamal; Pradier, Christian; Vasylyev, Marta; Mitsura, Victor; Vandekerckhove, Linos; Ostergaard, Lars; Clarke, Amanda; Degen, Olaf; Mulcahy, Fiona; Castagna, Antonella; Sthoeger, Zed; Flamholc, Leo; Sedláček, Dalibor; Mozer-Lisewska, Iwona; Lundgren, Jens D.

    2018-01-01

    Objective:The extent to which controlled and uncontrolled HIV interact with ageing, European region of care and calendar year of follow-up is largely unknown.Method:EuroSIDA participants were followed after 1 January 2001 and grouped according to current HIV progression risk; high risk (CD4(+) cell

  5. Efficacy of fix dose combination (atorvastatin and amlodipine) in treatment of uncontrolled hypertension and dyslipidemia

    International Nuclear Information System (INIS)

    Bashir, S.; Sherwani, M.U.K.; Batool, A.

    2012-01-01

    The fixed-dose combination containing the antihypertensive agent amlodipine and the statin, atorvastatin, is the first combination of its kind designed to treat two risk factors for cardiovascular disease (CVD), i.e., hypertension and dyslipidemia. in this study, blood pressure and lipid lowering effects of combination of amlodipine and atorvastatin were evaluated in uncontrolled hypertensive patients. Methods: Thirty patients both male and female in the age group 35-60 years attending the hypertensive clinic of PMRC FJMC suffering from uncontrolled hypertension were selected. baseline blood pressure was checked after half hour rest in sitting and standing position using mercury sphygmomanometer. Blood sample was collected from all patients after overnight fasting for assessment of serum cholesterol, triglycerides, LDL and HDL cholesterol levels. they were prescribed with fixed dose combination of 5 mg amlodipine and 10 mg atorvastatin. Patients were followed for their blood pressure measurement after every 4 weeks up to 12 weeks. At the end of 12 weeks their fasting blood sample was taken again for determination of serum cholesterol, triglyceride, IDL and HDL cholesterol levels. Results: Systolic blood pressure after 4, 8 and 12 weeks was significantly lower at all intervals from baseline. when systolic blood pressure after 8 and 12 weeks was compared with 4 weeks, the effect was again significant (p=0.024, p=0.002 respectively). There was no significant reduction seen in 8 versus 12 weeks (p=0.493). Diastolic blood pressure at 4, 8 and 12 weeks was significantly lower from baseline. Diastolic blood pressure after 4 and 8 weeks when compared with 8 and 12 weeks was not significantly low (p=0.99 and 0.91 respectively). Lipid profile of the patients was significantly reduced from baseline after twelve weeks of fixed dose combination of treatment (p<0.000). Conclusion: Combination therapy proved to be effective in controlling hypertension and dyslipidemia than single

  6. Efficacy of fix dose combination (atorvastatin and amlodipine) in treatment of uncontrolled hypertension and dyslipidemia

    Energy Technology Data Exchange (ETDEWEB)

    Bashir, S; Sherwani, M U.K.; Batool, A [Fatima Jinnah Medical College, Lahore (Pakistan)

    2012-07-15

    The fixed-dose combination containing the antihypertensive agent amlodipine and the statin, atorvastatin, is the first combination of its kind designed to treat two risk factors for cardiovascular disease (CVD), i.e., hypertension and dyslipidemia. in this study, blood pressure and lipid lowering effects of combination of amlodipine and atorvastatin were evaluated in uncontrolled hypertensive patients. Methods: Thirty patients both male and female in the age group 35-60 years attending the hypertensive clinic of PMRC FJMC suffering from uncontrolled hypertension were selected. baseline blood pressure was checked after half hour rest in sitting and standing position using mercury sphygmomanometer. Blood sample was collected from all patients after overnight fasting for assessment of serum cholesterol, triglycerides, LDL and HDL cholesterol levels. they were prescribed with fixed dose combination of 5 mg amlodipine and 10 mg atorvastatin. Patients were followed for their blood pressure measurement after every 4 weeks up to 12 weeks. At the end of 12 weeks their fasting blood sample was taken again for determination of serum cholesterol, triglyceride, IDL and HDL cholesterol levels. Results: Systolic blood pressure after 4, 8 and 12 weeks was significantly lower at all intervals from baseline. when systolic blood pressure after 8 and 12 weeks was compared with 4 weeks, the effect was again significant (p=0.024, p=0.002 respectively). There was no significant reduction seen in 8 versus 12 weeks (p=0.493). Diastolic blood pressure at 4, 8 and 12 weeks was significantly lower from baseline. Diastolic blood pressure after 4 and 8 weeks when compared with 8 and 12 weeks was not significantly low (p=0.99 and 0.91 respectively). Lipid profile of the patients was significantly reduced from baseline after twelve weeks of fixed dose combination of treatment (p<0.000). Conclusion: Combination therapy proved to be effective in controlling hypertension and dyslipidemia than single

  7. Physical and chemical stability of expired fixed dose combination artemether-lumefantrine in uncontrolled tropical conditions

    Directory of Open Access Journals (Sweden)

    Hess Kimberly

    2009-02-01

    Full Text Available Abstract Background New artemisinin combination therapies pose difficulties of implementation in developing and tropical settings because they have a short shelf-life (two years relative to the medicines they replace. This limits the reliability and cost of treatment, and the acceptability of this treatment to health care workers. A multi-pronged investigation was made into the chemical and physical stability of fixed dose combination artemether-lumefantrine (FDC-ALU stored under heterogeneous, uncontrolled African conditions, to probe if a shelf-life extension might be possible. Methods Seventy samples of expired FDC-ALU were collected from private pharmacies and malaria researchers in seven African countries. The samples were subjected to thin-layer chromatography (TLC, disintegration testing, and near infrared Raman spectrometry for ascertainment of active ingredients, tablet integrity, and chemical degradation of the tablet formulation including both active ingredients and excipients. Results Seventy samples of FDC-ALU were tested in July 2008, between one and 58 months post-expiry. 68 of 70 (97% samples passed TLC, disintegration and Raman spectrometry testing, including eight samples that were post-expiry by 20 months or longer. A weak linear association (R2 = 0.33 was observed between the age of samples and their state of degradation relative to brand-identical samples on Raman spectrometry. Sixty-eight samples were retested in February 2009 using Raman spectrometry, between eight and 65 months post-expiry. 66 of 68 (97% samples passed Raman spectrometry retesting. An unexpected observation about African drug logistics was made in three batches of FDC-ALU, which had been sold into the public sector at concessional pricing in accordance with a World Health Organization (WHO agreement, and which were illegally diverted to the private sector where they were sold for profit. Conclusion The data indicate that FDC-ALU is chemically and

  8. Mitigating the Impacts of Uncontrolled Air Flow on Indoor Environmental Quality and Energy Demand in Non-Residential Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Hugh I. Henderson; Jensen Zhang; James B. Cummings; Terry Brennan

    2006-07-31

    This multi-faceted study evaluated several aspects of uncontrolled air flows in commercial buildings in both Northern and Southern climates. Field data were collected from 25 small commercial buildings in New York State to understand baseline conditions for Northern buildings. Laboratory wall assembly testing was completed at Syracuse University to understand the impact of typical air leakage pathways on heat and moisture transport within wall assemblies for both Northern and Southern building applications. The experimental data from the laboratory tests were used to verify detailed heat and moisture (HAM) simulation models that could be used to evaluate a wider array of building applications and situations. Whole building testing at FSEC's Building Science Laboratory (BSL) systematically evaluated the energy and IAQ impacts of duct leakage with various attic and ceiling configurations. This systematic test carefully controlled all aspects of building performance to quantify the impact of duct leakage and unbalanced flow. The newest features of the EnergyPlus building simulation tool were used to model the combined impacts of duct leakage, ceiling leakage, unbalanced flows, and air conditioner performance. The experimental data provided the basis to validate the simulation model so it could be used to study the impact of duct leakage over a wide range of climates and applications. The overall objective of this project was to transfer work and knowledge that has been done on uncontrolled air flow in non-residential buildings in Florida to a national basis. This objective was implemented by means of four tasks: (1) Field testing and monitoring of uncontrolled air flow in a sample of New York buildings; (2) Detailed wall assembly laboratory measurements and modeling; (3) Whole building experiments and simulation of uncontrolled air flows; and (4) Develop and implement training on uncontrolled air flows for Practitioners in New York State.

  9. Optical remote sensing

    CERN Document Server

    Prasad, Saurabh; Chanussot, Jocelyn

    2011-01-01

    Optical remote sensing relies on exploiting multispectral and hyper spectral imagery possessing high spatial and spectral resolutions respectively. These modalities, although useful for most remote sensing tasks, often present challenges that must be addressed for their effective exploitation. This book presents current state-of-the-art algorithms that address the following key challenges encountered in representation and analysis of such optical remotely sensed data: challenges in pre-processing images, storing and representing high dimensional data, fusing different sensor modalities, patter

  10. REMOTE SENSING IN OCEANOGRAPHY.

    Science.gov (United States)

    remote sensing from satellites. Sensing of oceanographic variables from aircraft began with the photographing of waves and ice. Since then remote measurement of sea surface temperatures and wave heights have become routine. Sensors tested for oceanographic applications include multi-band color cameras, radar scatterometers, infrared spectrometers and scanners, passive microwave radiometers, and radar imagers. Remote sensing has found its greatest application in providing rapid coverage of large oceanographic areas for synoptic and analysis and

  11. Advanced Remote Sensing Research

    Science.gov (United States)

    Slonecker, Terrence; Jones, John W.; Price, Susan D.; Hogan, Dianna

    2008-01-01

    'Remote sensing' is a generic term for monitoring techniques that collect information without being in physical contact with the object of study. Overhead imagery from aircraft and satellite sensors provides the most common form of remotely sensed data and records the interaction of electromagnetic energy (usually visible light) with matter, such as the Earth's surface. Remotely sensed data are fundamental to geographic science. The Eastern Geographic Science Center (EGSC) of the U.S. Geological Survey (USGS) is currently conducting and promoting the research and development of three different aspects of remote sensing science: spectral analysis, automated orthorectification of historical imagery, and long wave infrared (LWIR) polarimetric imagery (PI).

  12. Remote Maintenance Monitoring System -

    Data.gov (United States)

    Department of Transportation — The Remote Maintenance and Monitoring System (RMMS) is a collection of subsystems that includes telecommunication components, hardware, and software, which serve to...

  13. Optical Remote Sensing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optical Remote Sensing Laboratory deploys rugged, cutting-edge electro-optical instrumentation for the collection of various event signatures, with expertise in...

  14. Remote Systems Design & Deployment

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, Sharon A.; Baker, Carl P.; Valdez, Patrick LJ

    2009-08-28

    The Pacific Northwest National Laboratory (PNNL) was tasked by Washington River Protection Solutions, LLC (WRPS) to provide information and lessons learned relating to the design, development and deployment of remote systems, particularly remote arm/manipulator systems. This report reflects PNNL’s experience with remote systems and lays out the most important activities that need to be completed to successfully design, build, deploy and operate remote systems in radioactive and chemically contaminated environments. It also contains lessons learned from PNNL’s work experiences, and the work of others in the national laboratory complex.

  15. Remote docking apparatus

    International Nuclear Information System (INIS)

    Dent, T.H.; Sumpman, W.C.; Wilhelm, J.J.

    1981-01-01

    The remote docking apparatus comprises a support plate with locking devices mounted thereon. The locking devices are capable of being inserted into tubular members for suspending the support plate therefrom. A vertical member is attached to the support plate with an attachment mechanism attached to the vertical member. A remote access manipulator is capable of being attached to the attachment mechanism so that the vertical member can position the remote access manipulator so that the remote access manipulator can be initially attached to the tubular members in a well defined manner

  16. Studies of Limits on Uncontrolled Heavy Ion Beam Losses for Allowing Hands-On Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Reginald M. Ronningen; Igor Remec

    2010-09-11

    Dose rates from accelerator components activated by 1 W/m beam losses are obtained semiempirically for a 1 GeV proton beam and by use of Monte Carlo transport codes for the proton beam and for 777 MeV/u 3He, 500 MeV/u 48Ca, 86Kr, 136Xe, and 400 MeV/u 238U ions. The dose rate obtained by the semi-empirical method, 0.99 mSv/h (99 mrem/h) at 30 cm, 4 h after 100 d irradiation by a 1-GeV proton beam, is consistent with studies at several accelerator facilities and with adopted hands-on maintenance dose rate limits. Monte Carlo simulations verify this result for protons and extend studies to heavy ion beam losses in drift-tube linac and superconducting linac accelerating structures. The studies indicate that the 1 W/m limit imposed on uncontrolled beam losses for high-energy proton beams might be relaxed for heavy ion beams. These studies further suggest that using the ratio of neutrons produced by a heavy ion beam to neutrons produced by a proton beam along with the dose rate from the proton beam (for thin-target scenarios) should allow an estimate of the dose rates expected from heavy ion beam losses.

  17. Simulation of thermal response of the 250 MWT modular HTGR during hypothetical uncontrolled heatup accidents

    International Nuclear Information System (INIS)

    Harrington, R.M.; Ball, S.J.

    1985-01-01

    One of the central design features of the 250 MWT modular HTGR is the ability to withstand uncontrolled heatup accidents without severe consequences. This paper describes calculational studies, conducted to test this design feature. A multi-node thermal-hydraulic model of the 250 MWT modular HTGR reactor core was developed and implemented in the IBM CSMP (Continuous System Modeling Program) simulation language. Survey calculations show that the loss of forced circulation accident with loss of steam generator cooling water and with accidental depressurization is the most severe heatup accident. The peak hot-spot fuel temperature is in the neighborhood of 1600 0 C. Fuel failure and fission product releases for such accidents would be minor. Sensitivity studies show that code input assumptions for thermal properties such as the side reflector conductivity have a significant effect on the peak temperature. A computer model of the reactor vessel cavity concrete wall and its surrounding earth was developed to simulate the extremely unlikely and very slowly-developing heatup accident that would take place if the worst-case loss of forced primary coolant circulation accident were further compounded by the loss of cooling water to the reactor vessel cavity liner cooling system. Results show that the ability of the earth surrounding the cavity to act as a satisfactory long-term heat sink is very sensitive to the assumed rate of decay heat generation and on the effective thermal conductivity of the earth

  18. Fibromyalgia as a cause of uncontrolled asthma: a case-control multicenter study.

    Science.gov (United States)

    Martinez-Moragon, Eva; Plaza, Vicente; Torres, Isabel; Rosado, Ana; Urrutia, Isabel; Casas, Xavier; Hinojosa, Belen; Blanco-Aparicio, Marina; Delgado, Julio; Quirce, Santiago; Sabadell, Carles; Cebollero, Pilar; Muñoz-Fernández, Ana

    2017-12-01

    Fibromyalgia can affect the control of asthma when both diseases are present in a single patient. To characterize asthma in patients with concomitant fibromyalgia to assess whether fibromyalgia is an independent factor of asthma severity that influences poor asthma control. We also evaluated how dyspnea is perceived by patients in order to demonstrate that alterations in the perception of airway obstruction may be responsible for poor asthma control. This was a cross-sectional case-control multicenter study, in which 56 patients in the asthma and fibromyalgia group were matched to 36 asthmatics by sex, approximate age, and asthma severity level. All patients were women. Study variables included the Asthma Control Test (ACT), the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), the Nijmegen hyperventilation syndrome questionnaire, the Hospital Anxiety and Depression Scale, and perception of dyspnea after acute bronchoconstriction. Although patients in both study groups showed similar asthma severity and use of anti-asthmatic drugs, patients in the asthma and fibromyalgia group showed lower scores on the ACT and MiniAQLQ questionnaires, and higher scores of anxiety and depression as well as hyperventilation compared to asthma patients without fibromyalgia. All these differences were statistically significant. Fibromyalgia in patients with asthma influences poor control of the respiratory disease and is associated with altered perception of dyspnea, hyperventilation syndrome, high prevalence of depression and anxiety, and impaired quality of life. Fibromyalgia may be considered a risk factor for uncontrolled asthma in patients suffering from asthma and fibromyalgia concomitantly.

  19. Leachate characterization and identification of dominant pollutants using leachate pollution index for an uncontrolled landfill site

    International Nuclear Information System (INIS)

    De, S.; Maiti, S. K.; Hazra, T.; Debsarkar, A.; Dutta, A.

    2016-01-01

    Landfill leachates are potential threats for environmental degradation. This study was conducted to determine the leachate quality, to identify the dominant pollutants and to evaluate the leachate pollution potential of an active and closed dumping ground of an uncontrolled municipal solid waste (MSW) landfill site in Kolkata, India using leachate pollution index. The results of the physico-chemical and biological analyses of leachate indicated that landfill site was in its methanogenic phase. Among the analysed leachate pollutants, TDS, BOD5, COD, TKN, NH3-N, Cl¯ , TCB, Pb, and Hg surpassed the leachate discharge standards for inland surface water as specified by the municipal solid waste (management and handling) rules, 2013 for both the dumping grounds. Moreover the concentrations of total Cr and Zn also exceeded the leachate disposal standards for the active dumping ground. The leachate pollution potentialities of both the active and closed dumping grounds were comparable as the overall LPI obtained 34.02 and 31.80 respectively. The overall LPI, LPI organic (LPIor), LPI inorganic (LPIin) and LPI heavy metals (LPIhm) of both the dumping grounds largely exceeded the LPI and sub-LPI values for treated leachate before disposal to the inland surface water. In terms of the individual pollution rating, total coliform bacteria, TKN, NH3-N and Hg were identified as the dominant pollutants and major contributing factors for the leachate pollution potential.

  20. Persistent toxic substances released from uncontrolled e-waste recycling and actions for the future.

    Science.gov (United States)

    Man, Ming; Naidu, Ravi; Wong, Ming H

    2013-10-01

    The Basel Convention on the Control of Transboundary Movement of Hazardous Wastes and their Disposal was adopted on March 22, 1989 and enforced on May 5, 1992. Since then, the USA, one of the world's largest e-waste producers, has not ratified this Convention or the Basel Ban Amendment. Communities are still debating the legal loophole, which permits the export of whole products to other countries provided it is not for recycling. In January 2011, China's WEEE Directive was implemented, providing stricter control over e-waste imports to China, including Hong Kong, while emphasizing that e-waste recycling is the producers' responsibility. China is expected to supersede the USA as the principal e-waste producer, by 2020, according to the UNEP. Uncontrolled e-waste recycling activities generate and release heavy metals and POPs into the environment, which may be re-distributed, bioaccumulated and biomagnified, with potentially adverse human health effects. Greater efforts and scientific approaches are needed for future e-product designs of minimal toxic metal and compound use, reaping greater benefits than debating the definition and handling responsibilities of e-waste recycling. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. The effect of ketotifen on inflammatory markers in allergic conjunctivitis: an open, uncontrolled study

    Directory of Open Access Journals (Sweden)

    Gagliardi Julio

    2003-01-01

    Full Text Available Abstract Background The efficacy and safety of ketotifen eye drop treatment in allergic conjunctivitis (AC management is perfectly known by several studies, but the mechanism of action at the biochemical levels is poorly understood so we decided to perform an open, uncontrolled study in order to investigate the effect of the topical administration of ketotifen fumarate 0.05% on biochemical markers of inflammation on conjunctival cells in patients with AC. Methods Nineteen patients with symptoms and signs of AC (itching, discharge, burning, redness, increase in the watery discharge, swelling and follicles and with a history of allergy were prescribed with two daily instillation of one drop of eyewash ketotifen fumarate 0,05% in both eyes during thirty days. They were studied by measuring clinical and immunologic parameters. Results Ketotifen fumarate treatment significantly reduced the total symptoms and signs score for each patient as well as each symptoms and signs at all time points compared with day 0 (p Conclusion Ketotifen besides the well-known effect in reducing signs and symptoms of AC significantly diminished production of eotaxin and expression of CD29 by epithelial cells in patients with seasonal AC.

  2. A simplified approach for slope stability analysis of uncontrolled waste dumps.

    Science.gov (United States)

    Turer, Dilek; Turer, Ahmet

    2011-02-01

    Slope stability analysis of municipal solid waste has always been problematic because of the heterogeneous nature of the waste materials. The requirement for large testing equipment in order to obtain representative samples has identified the need for simplified approaches to obtain the unit weight and shear strength parameters of the waste. In the present study, two of the most recently published approaches for determining the unit weight and shear strength parameters of the waste have been incorporated into a slope stability analysis using the Bishop method to prepare slope stability charts. The slope stability charts were prepared for uncontrolled waste dumps having no liner and leachate collection systems with pore pressure ratios of 0, 0.1, 0.2, 0.3, 0.4 and 0.5, considering the most critical slip surface passing through the toe of the slope. As the proposed slope stability charts were prepared by considering the change in unit weight as a function of height, they reflect field conditions better than accepting a constant unit weight approach in the stability analysis. They also streamline the selection of slope or height as a function of the desired factor of safety.

  3. Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience.

    Science.gov (United States)

    Chipps, Bradley E; Lanier, Bob; Milgrom, Henry; Deschildre, Antoine; Hedlin, Gunilla; Szefler, Stanley J; Kattan, Meyer; Kianifard, Farid; Ortiz, Benjamin; Haselkorn, Tmirah; Iqbal, Ahmar; Rosén, Karin; Trzaskoma, Benjamin; Busse, William W

    2017-05-01

    Asthma is one of the most common chronic diseases of childhood. Allergen sensitization and high frequencies of comorbid allergic diseases are characteristic of severe asthma in children. Omalizumab, an anti-IgE mAb, is the first targeted biologic therapeutic approved for the treatment of moderate-to-severe persistent allergic asthma (AA) that remains uncontrolled despite high-dose inhaled corticosteroids plus other controller medications. Since its initial licensing for use in adults and adolescents 12 years of age and older, the clinical efficacy, safety, and tolerability of omalizumab have been demonstrated in several published clinical trials in children aged 6 to less than 12 years with moderate-to-severe AA. These studies supported the approval of the pediatric indication (use in children aged ≥6 years) by the European Medicines Agency in 2009 and the US Food and Drug Administration in 2016. After this most recent change in licensing, we review the outcomes from clinical trials in children with persistent AA receiving omalizumab therapy and observational studies from the past 7 years of clinical experience in Europe. Data sources were identified by using PubMed in 2016. Guidelines and management recommendations and materials from the recent US Food and Drug Administration's Pediatric Advisory Committee meeting are also reviewed. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  4. [Severe uncontrolled asthma in patients over 75 years old: Treatment with omalizumab].

    Science.gov (United States)

    Romand, P; Kelkel, E; Saint-Raymond, C; Glas, N; Caillaud, D; Devouassoux, G

    2016-05-01

    With an aging population and an increase in the prevalence of asthma, this disease is becoming more common in the elderly. Nevertheless, the management of severe asthma can be complex, due to an increased risk of uncontrolled disease in patients over 65 years old and partly to the inherent characteristics of old age: comorbidities, underestimation of the role of allergies, poor adherence, difficulties with inhalation devices, etc. We report two cases of women over 75 with severe persistent allergic asthma not controlled by high doses of inhaled corticosteroids and long-acting beta-2-agonists in whom treatment with omalizumab was initiated. Following treatment with omalizumab a decrease in the number and severity of exacerbations, improved asthma control and dose reduction or discontinuation of systemic corticosteroids were observed. The tolerance of omalizumab was good in both cases. Omalizumab is to be considered an effective and well-tolerated therapeutic option for elderly patients with inadequately controlled severe allergic asthma. Copyright © 2015 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  5. Leachate characterization and identification of dominant pollutants using leachate pollution index for an uncontrolled landfill site

    Directory of Open Access Journals (Sweden)

    S. De

    2016-03-01

    Full Text Available Landfill leachates are potential threats for environmental degradation. This study was conducted to determine the leachate quality, to identify the dominant pollutants and to evaluate the leachate pollution potential of an active and closed dumping ground of an uncontrolled municipal solid waste landfill site in Kolkata, India using leachate pollution index. The results of the physico-chemical and biological analyses of leachate indicated that landfill site was in its methanogenic phase. Among the analysed leachate pollutants, TDS, BOD5, COD, TKN, NH3-N, Cl¯, TCB, Pb, and Hg surpassed the leachate discharge standards for inland surface water as specified by the municipal solid waste (Management and Handling Rules, 2013 for both the dumping grounds. Moreover the concentrations of total Cr and Zn also exceeded the leachate disposal standards for the active dumping ground. The leachate pollution potentialities of both the active and closed dumping grounds were comparable as the overall LPI obtained 34.02 and 31.80 respectively. The overall LPI, LPI organic (LPIor, LPI inorganic (LPIin and LPI heavy metals (LPIhm of both the dumping grounds largely exceeded the LPI and sub-LPI values for treated leachate before disposal to the inland surface water. In terms of the individual pollution rating, total coliform bacteria, TKN, NH3-N and Hg were identified as the dominant pollutants and major contributing factors for the leachate pollution potential.

  6. Perceptions of Insulin Treatment Among African Americans With Uncontrolled Type 2 Diabetes.

    Science.gov (United States)

    Bockwoldt, Denise; Staffileno, Beth A; Coke, Lola; Quinn, Lauretta

    2016-03-01

    Little is known regarding perception of insulin treatment among midlife and older African American (AA) adults with type 2 diabetes, or how perception affects self-management behaviors. Using the Roy adaptation model, this qualitative descriptive study explored the perception of insulin treatment in midlife and older AAs living with uncontrolled type 2 diabetes. Three 1-hour focus groups were conducted with a total of 13 participants. Thematic analysis of transcribed audio recordings used the constant comparative method. Themes identified include (a) insulin as instigator of negative emotions, (b) adapting to a lifestyle with insulin, and (c) becoming an insulin user: a new identity. Adapting to insulin is a psychosocial process that commonly results in negative emotions, identity conflict, and new roles. Further research is needed to understand how AA adults perceive insulin treatment, understand the role of perception in self-management behaviors, and determine whether interventions to change perceptions may be effective in improving adaptation to diabetes. © The Author(s) 2014.

  7. [The add-on effect of omalizumab on patients with uncontrolled bronchial asthma].

    Science.gov (United States)

    Minami, Yoshinori; Endo, Satoshi; Okumur, Shunsuke; Sasaki, Takaaki; Yamamoto, Yasushi; Ogasa, Toshiyuki; Osanai, Shinobu; Ohsaki, Yoshinobu

    2011-11-01

    A high-dose administration of inhaled corticosteroid is effective in the majority of patients with bronchial asthma, but is often difficult to attain sufficient control in certain subsets of patients. Omalizumab has recently emerged as a promising drug for bronchial asthma. To assess its add-on effect we administered omalizumab to patients with uncontrolled atopic asthma for more than 16 weeks and gave them questionnaires. The study population comprised 9 patients with frequent asthmatic symptoms despite the administration of high-dose inhaled corticosteroid and other disease controllers. We scored disease control using the Asthma Health Questionnaire-33-Japan and the Asthma Control Test, and evaluated the frequencies of short-acting beta2-agonist use for rescue and drip infusion of theophyllines and/or systemic steroids in a retrospective fashion. Asthmatic scores were significantly improved after 16 weeks of omalizumab therapy. The frequencies of reliever use and drip infusion were also decreased. These trends were present even in patients in whom no aeroallergen-specific IgE antibodies were detected. No statistically significant side effects were observed. Our study confirmed the add-on effect of omalizumab based on evaluation by simple questionnaires. Further studies are needed to clarify whether omalizumab therapy is suitable for patients without specific IgE antibodies.

  8. Ear Detection under Uncontrolled Conditions with Multiple Scale Faster Region-Based Convolutional Neural Networks

    Directory of Open Access Journals (Sweden)

    Yi Zhang

    2017-04-01

    Full Text Available Ear detection is an important step in ear recognition approaches. Most existing ear detection techniques are based on manually designing features or shallow learning algorithms. However, researchers found that the pose variation, occlusion, and imaging conditions provide a great challenge to the traditional ear detection methods under uncontrolled conditions. This paper proposes an efficient technique involving Multiple Scale Faster Region-based Convolutional Neural Networks (Faster R-CNN to detect ears from 2D profile images in natural images automatically. Firstly, three regions of different scales are detected to infer the information about the ear location context within the image. Then an ear region filtering approach is proposed to extract the correct ear region and eliminate the false positives automatically. In an experiment with a test set of 200 web images (with variable photographic conditions, 98% of ears were accurately detected. Experiments were likewise conducted on the Collection J2 of University of Notre Dame Biometrics Database (UND-J2 and University of Beira Interior Ear dataset (UBEAR, which contain large occlusion, scale, and pose variations. Detection rates of 100% and 98.22%, respectively, demonstrate the effectiveness of the proposed approach.

  9. A Case of Iris Melanocytoma Demonstrating Diffuse Melanocytic Proliferation with Uncontrolled Intraocular Pressure

    Directory of Open Access Journals (Sweden)

    Mami Kusunose

    2017-03-01

    Full Text Available We report a rare case with histologically proven melanocytoma of the iris that demonstrated diffuse melanocytic proliferation with uncontrolled secondary glaucoma and investigate the etiology of the intraocular pressure elevation. The patient was a 78-year-old man with a history of darkened iris of his left eye. The intraocular pressure was 39 mm Hg. A slit-lamp examination showed a diffuse darkened iris, and a gonioscopic examination revealed open angle with circumferential heavy pigmentation. There was no pigment dispersion of the anterior chamber and no pigment deposition of the cornea. We suspected malignant ring melanoma in the left eye and enucleated it. The globe was examined with light and electron microscopy. Light microscopy revealed the presence of heavily pigmented tumor cells in the iris, ciliary body, trabecular meshwork, and Schlemm’s canal. A bleached preparation showed large tumor cells with central and paracentral nuclei without mitosis. Electron microscopy of the trabecular meshwork revealed melanin-bearing tumor cells invading the intertrabecular spaces, and the melanin granules were not phagocytosed in the trabecular cells. The mechanical obstruction of the aqueous flow by the tumor cells may be a major cause of secondary glaucoma in eyes with iris melanocytoma presenting diffuse proliferation.

  10. Binary Large Object-Based Approach for QR Code Detection in Uncontrolled Environments

    Directory of Open Access Journals (Sweden)

    Omar Lopez-Rincon

    2017-01-01

    Full Text Available Quick Response QR barcode detection in nonarbitrary environment is still a challenging task despite many existing applications for finding 2D symbols. The main disadvantage of recent applications for QR code detection is a low performance for rotated and distorted single or multiple symbols in images with variable illumination and presence of noise. In this paper, a particular solution for QR code detection in uncontrolled environments is presented. The proposal consists in recognizing geometrical features of QR code using a binary large object- (BLOB- based algorithm with subsequent iterative filtering QR symbol position detection patterns that do not require complex processing and training of classifiers frequently used for these purposes. The high precision and speed are achieved by adaptive threshold binarization of integral images. In contrast to well-known scanners, which fail to detect QR code with medium to strong blurring, significant nonuniform illumination, considerable symbol deformations, and noising, the proposed technique provides high recognition rate of 80%–100% with a speed compatible to real-time applications. In particular, speed varies from 200 ms to 800 ms per single or multiple QR code detected simultaneously in images with resolution from 640 × 480 to 4080 × 2720, respectively.

  11. The Analysis of Uncontrolled CEA Bank withdrawal from low power Accident for APR1400 Using KNAP

    International Nuclear Information System (INIS)

    Yang, Chang-Keun; Kim, Yo-Han; Ha, Sang-Jun

    2006-01-01

    In Korea, the nuclear industries such as fuel manufacturer, the architect engineer and the utility, have been using the methodologies and codes of vendors, such as Westinghouse(WH), Combustion Engineering(CE), for the safety analyses of nuclear power plants. Consequently the industries have kept up the many organizations to operate the methodologies and to maintain the codes for each vendor. It may cause difficulty to improve the safety analyses efficiency and technology related. So, the necessity another of methodologies and code systems applicable to Non- LOCA, beyond design basis accident and performance analyses for all types of pressurized water reactor (PWR) has been raised. As the first requirement, the best-estimate codes were required for applicable wider application area and realistic behavior prediction of power plants with various and sophisticated functions. After the review on several candidates, RETRAN-3D has been chosen as a system analysis code. The draft version of the methodology was developed based on the references for the general purpose, and modified to apply it to specific plants in Korea. As a part of the feasibility estimation for the methodology and code system, uncontrolled CEA bank withdrawal from low power accident for the Advanced Power Reactor 1400(APR1400) was selected to verify the feasibility using the RETRAN-3D. And the results were compared with the Standard Safety Analysis Reports (SSAR) of APR1400

  12. Long-Term Use of Aldosterone-Receptor Antagonists in Uncontrolled Hypertension: A Retrospective Analysis

    Directory of Open Access Journals (Sweden)

    Pieter M. Jansen

    2011-01-01

    Full Text Available Background. The long-term efficacy of aldosterone-receptor antagonists (ARAs as add-on treatment in uncontrolled hypertension has not yet been reported. Methods. Data from 123 patients (21 with primary aldosteronism, 102 with essential hypertension with difficult-to-treat hypertension who received an ARA between May 2005 and September 2009 were analyzed retrospectively for their blood pressure (BP and biochemical response at first followup after start with ARA and the last follow-up available. Results. Systolic BP decreased by 22±20 and diastolic BP by 9.4±12 mmHg after a median treatment duration of 25 months. In patients that received treatment >5 years, SBP was 33±20 and DBP was 16 ± 13 mmHg lower than at baseline. Multivariate analysis revealed that baseline BP and follow-up duration were positively correlated with BP response. Conclusion. Add-on ARA treatment in difficult-to-treat hypertension results in a profound and sustained BP reduction.

  13. Effectiveness of a behavior modification program for older people with uncontrolled type 2 diabetes.

    Science.gov (United States)

    Ounnapiruk, Liwan; Wirojratana, Virapun; Meehatchai, Nitaya; Turale, Sue

    2014-06-01

    This quasi-experimental study examined the effectiveness of a behavior modification program for diabetic control in Thai elders with uncontrolled Type 2 Diabetes. Purposive sampling was used to select 30 elders from one community as an intervention group, and 30 from a neighboring community as a control group. The intervention group participated in a program of 12 weeks' duration involving activities related to group counseling, group discussion, and an empowerment process that enhanced appropriate consumption of healthy diet, medication taking, and exercise. Data were collected by interviews using a questionnaire to assess knowledge of diabetes, perceived self-efficacy, and diabetes control behavior, including fasting blood glucose and glycosylated hemoglobin, were examined at the baseline and three months thereafter. At program completion, the intervention group had significantly higher scores of knowledge, self-efficacy, and health behaviors than those in the control group, but blood glucose and glycosylated hemoglobin were not significantly different. Although nurses can use aspects of this program to benefit elders with diabetes who require support and education, further research is required to provide improved health outcomes such as better glycemic control. © 2013 Wiley Publishing Asia Pty Ltd.

  14. Isolation, purification and analysis of dissolved organic carbon from Gohagoda uncontrolled open dumpsite leachate, Sri Lanka.

    Science.gov (United States)

    Vithanage, Meththika; Wijesekara, Hasintha; Mayakaduwa, S S

    2017-07-01

    Extract and analysis of the Dissolved Organic Carbon (DOC) fractions were analyzed from the leachate of an uncontrolled dumpsite at Gohagoda, Sri Lanka. DOC fractions, humic acid (HA), fulvic acid (FA) and the hydrophilic (Hyd) fractions were isolated and purified with the resin techniques. Spectroscopic techniques and elemental analysis were performed to characterize DOCs. Maximum TOC and DOC values recorded were 56,955 and 28,493 mg/L, respectively. Based on the total amount of DOC fractionation, Hyd dominated accounting for ∼60%, and HA and FA constituted ∼22% and ∼17%, respectively, exhibiting the mature phase of the dumpsite. The elemental analysis of DOCs revealed carbon variation following HA > FA > Hyd, while hydrogen and nitrogen were similar in each fraction. The N/C ratio for HA was recorded as 0.18, following a similar trend in old dumpsite leachate elsewhere. The O/C ratios for HA and FA were recorded higher as much as 1.0 and 9.3, respectively, indicating high degree of carbon mineralization in the leachates. High content of carboxylic, phenolic and lactone groups in all DOCs was observed disclosing their potential for toxic substances transportation. The results strongly suggest the risk associated with DOCs in dumpsite leachate to the aquatic and terrestrial environment.

  15. Detecting Motor Impairment in Early Parkinson's Disease via Natural Typing Interaction With Keyboards: Validation of the neuroQWERTY Approach in an Uncontrolled At-Home Setting.

    Science.gov (United States)

    Arroyo-Gallego, Teresa; Ledesma-Carbayo, María J; Butterworth, Ian; Matarazzo, Michele; Montero-Escribano, Paloma; Puertas-Martín, Verónica; Gray, Martha L; Giancardo, Luca; Sánchez-Ferro, Álvaro

    2018-03-26

    Parkinson's disease (PD) is the second most prevalent neurodegenerative disease and one of the most common forms of movement disorder. Although there is no known cure for PD, existing therapies can provide effective symptomatic relief. However, optimal titration is crucial to avoid adverse effects. Today, decision making for PD management is challenging because it relies on subjective clinical evaluations that require a visit to the clinic. This challenge has motivated recent research initiatives to develop tools that can be used by nonspecialists to assess psychomotor impairment. Among these emerging solutions, we recently reported the neuroQWERTY index, a new digital marker able to detect motor impairment in an early PD cohort through the analysis of the key press and release timing data collected during a controlled in-clinic typing task. The aim of this study was to extend the in-clinic implementation to an at-home implementation by validating the applicability of the neuroQWERTY approach in an uncontrolled at-home setting, using the typing data from subjects' natural interaction with their laptop to enable remote and unobtrusive assessment of PD signs. We implemented the data-collection platform and software to enable access and storage of the typing data generated by users while using their computer at home. We recruited a total of 60 participants; of these participants 52 (25 people with Parkinson's and 27 healthy controls) provided enough data to complete the analysis. Finally, to evaluate whether our in-clinic-built algorithm could be used in an uncontrolled at-home setting, we compared its performance on the data collected during the controlled typing task in the clinic and the results of our method using the data passively collected at home. Despite the randomness and sparsity introduced by the uncontrolled setting, our algorithm performed nearly as well in the at-home data (area under the receiver operating characteristic curve [AUC] of 0.76 and

  16. Hyperspectral remote sensing

    CERN Document Server

    Eismann, Michael

    2012-01-01

    Hyperspectral remote sensing is an emerging, multidisciplinary field with diverse applications that builds on the principles of material spectroscopy, radiative transfer, imaging spectrometry, and hyperspectral data processing. This book provides a holistic treatment that captures its multidisciplinary nature, emphasizing the physical principles of hyperspectral remote sensing.

  17. Remote actuated valve implant

    Science.gov (United States)

    McKnight, Timothy E; Johnson, Anthony; Moise, Jr., Kenneth J; Ericson, Milton Nance; Baba, Justin S; Wilgen, John B; Evans, III, Boyd McCutchen

    2014-02-25

    Valve implant systems positionable within a flow passage, the systems having an inlet, an outlet, and a remotely activatable valve between the inlet and outlet, with the valves being operable to provide intermittent occlusion of the flow path. A remote field is applied to provide thermal or magnetic activation of the valves.

  18. Remote handling at LAMPF

    International Nuclear Information System (INIS)

    Grisham, D.L.; Lambert, J.E.

    1983-01-01

    Experimental area A at the Clinton P. Anderson Meson Physics Facility (LAMPF) encompasses a large area. Presently there are four experimental target cells along the main proton beam line that have become highly radioactive, thus dictating that all maintenance be performed remotely. The Monitor remote handling system was developed to perform in situ maintenance at any location within area A. Due to the complexity of experimental systems and confined space, conventional remote handling methods based upon hot cell and/or hot bay concepts are not workable. Contrary to conventional remote handling which require special tooling for each specifically planned operation, the Monitor concept is aimed at providing a totally flexible system capable of remotely performing general mechanical and electrical maintenance operations using standard tools. The Monitor system is described

  19. Remote vehicle survey tool

    International Nuclear Information System (INIS)

    Armstrong, G.A.; Burks, B.L.; Kress, R.L.; Wagner, D.G.; Ward, C.R.

    1993-01-01

    The Remote Vehicle Survey Tool (RVS7) is a color graphical display tool for viewing remotely acquired scientific data. The RVST displays the data in the form of a color two-dimensional world model map. The world model map allows movement of the remote vehicle to be tracked by the operator and the data from sensors to be graphically depicted in the interface. Linear and logarithmic meters, dual channel oscilloscopes, and directional compasses are used to display sensor information. The RVST is user-configurable by the use of ASCII text files. The operator can configure the RVST to work with any remote data acquisition system and teleoperated or autonomous vehicle. The modular design of the RVST and its ability to be quickly configured for varying system requirements make the RVST ideal for remote scientific data display in all environmental restoration and waste management programs

  20. Previous Ketamine Produces an Enduring Blockade of Neurochemical and Behavioral Effects of Uncontrollable Stress

    Science.gov (United States)

    Dolzani, Samuel D.; Tilden, Scott; Christianson, John P.; Kubala, Kenneth H.; Bartholomay, Kristi; Sperr, Katherine; Ciancio, Nicholas; Watkins, Linda R.; Maier, Steven F.

    2016-01-01

    Recent interest in the antidepressant and anti-stress effects of subanesthetic doses of ketamine, an NMDA receptor antagonist, has identified mechanisms whereby ketamine reverses the effect of stress, but little is known regarding the prophylactic effect ketamine might have on future stressors. Here we investigate the prophylactic effect of ketamine against neurochemical and behavioral changes that follow inescapable, uncontrollable tail shocks (ISs) in Sprague Dawley rats. IS induces increased anxiety, which is dependent on activation of serotonergic (5-HT) dorsal raphe nucleus (DRN) neurons that project to the basolateral amygdala (BLA). Ketamine (10 mg/kg, i.p.) administered 2 h, 1 week, or 2 weeks before IS prevented the increased extracellular levels of 5-HT in the BLA typically produced by IS. In addition, ketamine administered at these time points blocked the decreased juvenile social investigation produced by IS. Microinjection of ketamine into the prelimbic (PL) region of the medial prefrontal cortex duplicated the effects of systemic ketamine, and, conversely, systemic ketamine effects were prevented by pharmacological inhibition of the PL. Although IS does not activate DRN-projecting neurons from the PL, IS did so after ketamine, suggesting that the prophylactic effect of ketamine is a result of altered functioning of this projection. SIGNIFICANCE STATEMENT The reported data show that systemic ketamine, given up to 2 weeks before a stressor, blunts behavioral and neurochemical effects of the stressor. The study also advances understanding of the mechanisms involved and suggests that ketamine acts at the prelimbic cortex to sensitize neurons that project to and inhibit the DRN. PMID:26740657

  1. A Study on Re-entry Predictions of Uncontrolled Space Objects for Space Situational Awareness

    Science.gov (United States)

    Choi, Eun-Jung; Cho, Sungki; Lee, Deok-Jin; Kim, Siwoo; Jo, Jung Hyun

    2017-12-01

    The key risk analysis technologies for the re-entry of space objects into Earth’s atmosphere are divided into four categories: cataloguing and databases of the re-entry of space objects, lifetime and re-entry trajectory predictions, break-up models after re-entry and multiple debris distribution predictions, and ground impact probability models. In this study, we focused on re- entry prediction, including orbital lifetime assessments, for space situational awareness systems. Re-entry predictions are very difficult and are affected by various sources of uncertainty. In particular, during uncontrolled re-entry, large spacecraft may break into several pieces of debris, and the surviving fragments can be a significant hazard for persons and properties on the ground. In recent years, specific methods and procedures have been developed to provide clear information for predicting and analyzing the re-entry of space objects and for ground-risk assessments. Representative tools include object reentry survival analysis tool (ORSAT) and debris assessment software (DAS) developed by National Aeronautics and Space Administration (NASA), spacecraft atmospheric re-entry and aerothermal break-up (SCARAB) and debris risk assessment and mitigation analysis (DRAMA) developed by European Space Agency (ESA), and semi-analytic tool for end of life analysis (STELA) developed by Centre National d’Etudes Spatiales (CNES). In this study, various surveys of existing re-entry space objects are reviewed, and an efficient re-entry prediction technique is suggested based on STELA, the life-cycle analysis tool for satellites, and DRAMA, a re-entry analysis tool. To verify the proposed method, the re-entry of the Tiangong-1 Space Lab, which is expected to re-enter Earth’s atmosphere shortly, was simulated. Eventually, these results will provide a basis for space situational awareness risk analyses of the re-entry of space objects.

  2. Recombinant-activated factor VII in patients with uncontrolled bleeding: A retrospective observational analysis

    Directory of Open Access Journals (Sweden)

    Said D Abuhasna

    2012-01-01

    Full Text Available Background: Factor VIIa (recombinant has an off-label use to control life-threatening bleeding that is refractory to other measures and was shown to decrease transfusion requirements. Objective: The primary objective of this study was to assess the safety and effectiveness of factor VIIa (recombinant on blood transfusion requirements and coagulation parameters when used in patients whose bleeding was uncorrected by other means. The pharmacoeconomic impact for any discrepancy from our protocol was evaluated. Secondary outcomes included 4-hour and 28-day mortality, as well as safety of this agent in terms of thromboembolic complications. Materials and Methods: We retrospectively evaluated patients who received recombinant-activated factor VII (rFVIIa for uncontrolled bleeding from June 2008 to April 2011. The medical records of 33 patients were evaluated. Coagulation parameters and blood products were determined 24 hours before and 24 hours after administration of rFVIIa, and the results compared. Patients were also screened for any thromboembolic complications. Results: Administration of rFVIIa reduced blood transfusion requirements and improved coagulation parameters significantly (P<0.05. No thromboembolic complications were reported. Most of the dosing was consistent with those recommended in our institutional protocol, with discrepancies resulting in an average cost of $56 058. Moreover, pH was reported in only 67% of patients. All patients treated with rFVIIa survived up to 4 hours after receiving this agent, while the 28-day mortality was 24% (8/33. Conclusion: The use of rFVIIa appears to be safe and effective in promoting hemostasis, as evident from reducing transfusion requirements and improving the coagulation variables.

  3. Design of a rotary for an uncontrolled multi-leg intersection in Chennai, India

    Science.gov (United States)

    Vasantha Kumar, S.; Gulati, Himanshu; Arora, Shivam

    2017-11-01

    One way to control the traffic at busy intersections is to construct a roundabout or rotary intersection, which is a special type of at-grade intersection, where all converging vehicles are forced to move round a central island in clock-wise direction. The present study aims to design a rotary for an uncontrolled multi leg intersection located in Royapetah in Chennai, India. The intersection has five approach roads with two-way traffic in all the approach roads and there is no signal or traffic police to control the traffic at present and hence experiences traffic chaos during peak hours. In order to design the rotary, it is essential to have the information on traffic volumes coming from the approach roads. For this, a video data collection was carried out for a duration of eight hours from 7.30 am to 11.30 am and from 2.30 pm to 6.30 pm on a typical working day using a handycam from the terrace of an apartment building located near the intersection. During data extraction stage, each 5 min. traffic volume was extracted for all the five classes of vehicles considered and were converted to passenger car units (PCU). The analysis of traffic data showed that during peak hour from 4.45 pm to 5.45 pm, the proportion of weaving traffic, i.e., ratio of sum of crossing streams to the total traffic on the weaving section was found to be 0.81. According to Indian road congress (IRC) guidelines, this proportion can take any value between 0.4 and 1 and in the present study, the calculated value is found to be within the prescribed range. Using the calculated values of average entry width of the rotary and width & length of weaving section, the practical capacity of the rotary was found to be 3020 PCUs which is well above the observed traffic volume of 2665 PCUs.

  4. Renal sympathetic denervation in uncontrolled arterial hypertension after successful repair for aortic coarctation.

    Science.gov (United States)

    Lurz, Philipp; Okon, Thomas; Riede, Thomas; Wagner, Robert; Schuler, Gerhard; Daehnert, Ingo; Desch, Steffen

    2016-01-01

    Uncontrolled arterial hypertension is a frequent problem after successful repair of CoA and has been attributed to increased central sympathetic drive as well as a blunted baroreceptor reflex. RSD is a promising therapy to reduce central sympathetic drive and improve baroreflex sensitivity. 8 patients (age: 27±6 years) with previous surgical and/or percutaneous repair of CoA, absence of any relevant restenosis (invasive gradient across the site of previous treatment 3±4 mmHg) and resistant arterial hypertension (daytime SBP≥140 mmHg on 24 hour ambulatory blood pressure measurements [ABPM] in spite of the concurrent use of 3 antihypertensive agents of different classes or intolerance to BP medications) were included. Bilateral RSD was performed using the Symplicity Flex™ catheter (Medtronic, MN, USA). RSD was successful in all patients with no procedural complications and no evidence for renal artery stenosis 6 months post procedure. From baseline to 6 month follow-up, RSD was followed by a significant reduction in average daytime systolic BP (150.4±7.8 to 143.1±8.0 mmHg; p=0.0117) as well as systolic BP throughout 24 h (146.8±7.3 vs. 140.5±7.8, p=0.04). The BP reductions observed in these patients justify engaging in a larger clinical trial on the efficacy of RSD in this specific type of secondary hypertension and bares the hope that RSD might extend the currently very limited armory against arterial hypertension in young adults with previous repair of CoA. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  5. Persistent toxic substances released from uncontrolled e-waste recycling and actions for the future

    International Nuclear Information System (INIS)

    Man, Ming; Naidu, Ravi; Wong, Ming H.

    2013-01-01

    The Basel Convention on the Control of Transboundary Movement of Hazardous Wastes and their Disposal was adopted on March 22, 1989 and enforced on May 5, 1992. Since then, the USA, one of the world's largest e-waste producers, has not ratified this Convention or the Basel Ban Amendment. Communities are still debating the legal loophole, which permits the export of whole products to other countries provided it is not for recycling. In January 2011, China's WEEE Directive was implemented, providing stricter control over e-waste imports to China, including Hong Kong, while emphasizing that e-waste recycling is the producers' responsibility. China is expected to supersede the USA as the principal e-waste producer, by 2020, according to the UNEP. Uncontrolled e-waste recycling activities generate and release heavy metals and POPs into the environment, which may be re-distributed, bioaccumulated and biomagnified, with potentially adverse human health effects. Greater efforts and scientific approaches are needed for future e-product designs of minimal toxic metal and compound use, reaping greater benefits than debating the definition and handling responsibilities of e-waste recycling. - Highlights: ► We recommended to ban uses of deca-BDE in addition to penta- and octa-BDEs. ► We suggested to replace PVC in electronic products with non-chlorinated polymers. ► Spend less time on debating responsibilities and definition of e-waste and recycling. ► Proposed to work more on eliminating sources and potentials of toxic substances

  6. Modes of uncontrolled rotational motion of the Progress M-29M spacecraft

    Science.gov (United States)

    Belyaev, M. Yu.; Matveeva, T. V.; Monakhov, M. I.; Rulev, D. N.; Sazonov, V. V.

    2018-01-01

    We have reconstructed the uncontrolled rotational motion of the Progress M-29M transport cargo spacecraft in the single-axis solar orientation mode (the so-called sunward spin) and in the mode of the gravitational orientation of a rotating satellite. The modes were implemented on April 3-7, 2016 as a part of preparation for experiments with the DAKON convection sensor onboard the Progress spacecraft. The reconstruction was performed by integral statistical techniques using the measurements of the spacecraft's angular velocity and electric current from its solar arrays. The measurement data obtained in a certain time interval have been jointly processed using the least-squares method by integrating the equations of the spacecraft's motion relative to the center of mass. As a result of processing, the initial conditions of motion and parameters of the mathematical model have been estimated. The motion in the sunward spin mode is the rotation of the spacecraft with an angular velocity of 2.2 deg/s about the normal to the plane of solar arrays; the normal is oriented toward the Sun or forms a small angle with this direction. The duration of the mode is several orbit passes. The reconstruction has been performed over time intervals of up to 1 h. As a result, the actual rotational motion of the spacecraft relative to the Earth-Sun direction was obtained. In the gravitational orientation mode, the spacecraft was rotated about its longitudinal axis with an angular velocity of 0.1-0.2 deg/s; the longitudinal axis executed small oscillated relative to the local vertical. The reconstruction of motion relative to the orbital coordinate system was performed in time intervals of up to 7 h using only the angularvelocity measurements. The measurements of the electric current from solar arrays were used for verification.

  7. Persistent toxic substances released from uncontrolled e-waste recycling and actions for the future

    Energy Technology Data Exchange (ETDEWEB)

    Man, Ming [Croucher Institute for Environmental Sciences, Hong Kong Baptist University (Hong Kong); Naidu, Ravi [Cooperative Research Centre for Contamination Assessment and Remediation of Environments (CRC CARE), University of South Australia (Australia); Wong, Ming H., E-mail: mhwong@hkbu.edu.hk [Croucher Institute for Environmental Sciences, Hong Kong Baptist University (Hong Kong)

    2013-10-01

    The Basel Convention on the Control of Transboundary Movement of Hazardous Wastes and their Disposal was adopted on March 22, 1989 and enforced on May 5, 1992. Since then, the USA, one of the world's largest e-waste producers, has not ratified this Convention or the Basel Ban Amendment. Communities are still debating the legal loophole, which permits the export of whole products to other countries provided it is not for recycling. In January 2011, China's WEEE Directive was implemented, providing stricter control over e-waste imports to China, including Hong Kong, while emphasizing that e-waste recycling is the producers' responsibility. China is expected to supersede the USA as the principal e-waste producer, by 2020, according to the UNEP. Uncontrolled e-waste recycling activities generate and release heavy metals and POPs into the environment, which may be re-distributed, bioaccumulated and biomagnified, with potentially adverse human health effects. Greater efforts and scientific approaches are needed for future e-product designs of minimal toxic metal and compound use, reaping greater benefits than debating the definition and handling responsibilities of e-waste recycling. - Highlights: ► We recommended to ban uses of deca-BDE in addition to penta- and octa-BDEs. ► We suggested to replace PVC in electronic products with non-chlorinated polymers. ► Spend less time on debating responsibilities and definition of e-waste and recycling. ► Proposed to work more on eliminating sources and potentials of toxic substances.

  8. Counterfactual reasoning for regretted situations involving controllable versus uncontrollable events: the modulating role of contingent self-esteem.

    Science.gov (United States)

    Wilkinson, Meredith R; Ball, Linden J; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person's sense of self-worth is based on self and others' expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future.

  9. Counterfactual Reasoning for Regretted Situations Involving Controllable Versus Uncontrollable Events: The Modulating Role of Contingent Self-Esteem

    Science.gov (United States)

    Wilkinson, Meredith R.; Ball, Linden J.; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person’s sense of self-worth is based on self and others’ expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future. PMID:25883697

  10. Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009

    Directory of Open Access Journals (Sweden)

    Chew Boon How

    2012-05-01

    Full Text Available Abstract Background Uncontrolled blood pressure (BP is a significant contributor of morbidity and even mortality in type 2 diabetes (T2D patients. This study was done to determine the significant determinants of uncontrolled blood pressure in T2D patients in Malaysia. Methods Between 1st January 2009 to 31st December 2009, data from 70 889 patients with Type 2 diabetes was obtained from the Adult Diabetes Control and Management Registry for analysis; 303 centers participated in the study. Their demographic characteristics, the nature of their diabetes, their state of hypertension, treatment modalities, risk factors, and complications are described. Based on their most recent BP values, subjects were divided into controlled BP and uncontrolled BP and their clinical determinants compared. Independent determinants were identified using multivariate logistic regression. Results The mean age of patients at diagnosis of diabetes was 52.3 ± 11.1 years old. Most were women (59.0 % and of Malay ethnicity (61.9 %. The mean duration of diabetes was 5.9 ± 5.6 years. A total of 57.4 % were hypertensive. Of the 56 503 blood pressure (BP measured, 13 280 (23.5 % patients had BP two anti-hypertensive agents. Health clinics without doctor, older age (≥ 50 years old, shorter duration of diabetes ( Conclusions Major independent determinants of uncontrolled BP in our group of T2D patients were Malay ethnicity, older age, recent diagnosis of diabetes, overweight and follow-up at health clinics without a doctor and possibly the improper use of anti hypertensive agent. More effort, education and resources, especially in the primary health care centres are needed to improve hypertensive care among our patients with diabetes.

  11. Cardiovascular morbidity of severe resistant hypertension among treated uncontrolled hypertensives: a 4-year follow-up study.

    Science.gov (United States)

    Kasiakogias, Alexandros; Tsioufis, Costas; Dimitriadis, Kyriakos; Konstantinidis, Dimitrios; Koumelli, Areti; Leontsinis, Ioannis; Andrikou, Eirini; Vogiatzakis, Nikos; Marinaki, Smaragdi; Petras, Dimitrios; Fragoulis, Christos; Konstantinou, Konstantinos; Papademetriou, Vasilios; Tousoulis, Dimitrios

    2018-05-01

    Data regarding the prognosis of resistant hypertension (RHTN) with respect to its severity is limited. We investigated the cardiovascular risk of severe RHTN in a prospective observational study. A cohort of 1700 hypertensive patient with treated uncontrolled HTN was followed for a mean period of 3.6 ± 1.8 years. At baseline, standard clinical and laboratory workup was performed, including testing for secondary causes of RHT where applicable. Three groups were identified depending on presence of RHTN (office-based uncontrolled HTN under at least three drugs including a diuretic) and levels of office systolic blood pressure (BP): 1187 patients (70%) without RHTN, 313 (18%) with not-severe RHTN (systolic BP < 160 mmHg) and 200 (12%) with severe RHTN (systolic BP ≥ 160 mmHg). Endpoint of interest was cardiovascular morbidity set as the composite of coronary heart disease and stroke. During follow-up, incidence rates of cardiovascular events per 1000 person-years were 7.1 cases in the non-RHTN group, 12.4 cases in the not-severe RHTN group and 18 cases in the severe RHTN group. Unadjusted analysis showed that compared to uncontrolled patients without RHTN, patients with not-severe RHTN exhibited a similar risk but patients with severe RHTN had a significantly higher risk, by 2.5 times (CI: 1.28-4.73, p = 0.007). Even after multivariate adjustment for established risk factors including BP levels and isolated systolic HTN, severe RHTN remained as an independent predictor of the cardiovascular outcome (OR: 2.30, CI: 1.00-5.29, p = 0.05). In conclusion, among treated yet uncontrolled hypertensive patients, severe RHTN exhibits a significantly higher cardiovascular risk indicating the need for prompt management.

  12. Evaluation of long-term safety and efficacy of omalizumab in elderly patients with uncontrolled allergic asthma.

    Science.gov (United States)

    Tat, Tugba Songul; Cilli, Aykut

    2016-11-01

    Severe asthma management in elderly patients may be difficult because of increased comorbid conditions, polypharmacy, physiologic changes that occur with aging, incorrect use of inhaler devices, and poor adherence. To evaluate the long-term safety and efficacy of the anti-IgE antibody omalizumab in elderly (aged ≥65 years) patients with uncontrolled allergic asthma. The efficiency and adverse effects of omalizumab treatment were evaluated based on data extracted from medical records. Patients were evaluated monthly for efficacy and adverse reactions. Treatment efficacy was evaluated by level of asthma symptom control, using the Global Initiative for Asthma guideline. Nineteen consecutive elderly patients with asthma (female to male ratio, 14:5) formed our cohort. The mean (SD) age, disease duration, and total IgE level were 69.3 (5.8) years, 19.4 (8.6) years, and 299.1 (197.2) IU/mL, respectively. The mean (SD) duration of omalizumab treatment was 35.6 (17.8) months (range, 9-66 months). All the patients had at least 1 perennial inhalant allergen sensitivity and had uncontrolled allergic asthma. Elderly patients experienced no significantly important adverse reaction considered to be related to omalizumab treatment. Only 1 patient had a local adverse reaction and 1 had myalgia that was considered to be drug related. After omalizumab treatment, asthma symptoms were well controlled in 9 patients (47.4%) and partly controlled in 8 patients (42.1%). Two of the patients (10.5%) still had uncontrolled asthma. Our study found that omalizumab is a well-tolerated and effective therapy for elderly patients with uncontrolled asthma. Copyright © 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  13. Shock progression and survival after use of a condom uterine balloon tamponade package in women with uncontrolled postpartum hemorrhage.

    Science.gov (United States)

    Burke, Thomas F; Danso-Bamfo, Sandra; Guha, Moytrayee; Oguttu, Monica; Tarimo, Vincent; Nelson, Brett D

    2017-10-01

    To examine the outcomes of women in advanced shock from uncontrolled postpartum hemorrhage (PPH) who underwent placement of an Every Second Matters for Mothers and Babies Uterine Balloon Tamponade (ESM-UBT) device. In a prospective case series, data were collected for women who received an ESM-UBT device at healthcare facilities in Kenya, Senegal, Sierra Leone, and Tanzania between September 1, 2012, and September 30, 2016. Shock class was assigned on the basis of recorded blood pressures and mental status at the time of UBT placement. Data for 306 women with uncontrolled PPH from uterine atony across 117 facilities were analyzed. Normal vital signs or class I/II shock were reported for 166 (54.2%). In this group, one death occurred and was attributed to PPH (survival rate 99.4%). There were no cases of shock progression. One hundred and eleven (36.3%) were in class III shock and 29 (9.5%) in class IV shock; the respective survival rates were 97.3% (n=108) and 86.2% (n=25). The ESM-UBT device arrests hemorrhage, prevents shock progression, and is associated with high survival rates among women with uncontrolled PPH from uterine atony. © 2017 International Federation of Gynecology and Obstetrics.

  14. Out of control mortality matters: the effect of perceived uncontrollable mortality risk on a health-related decision.

    Science.gov (United States)

    Pepper, Gillian V; Nettle, Daniel

    2014-01-01

    Prior evidence from the public health literature suggests that both control beliefs and perceived threats to life are important for health behaviour. Our previously presented theoretical model generated the more specific hypothesis that uncontrollable, but not controllable, personal mortality risk should alter the payoff from investment in health protection behaviours. We carried out three experiments to test whether altering the perceived controllability of mortality risk would affect a health-related decision. Experiment 1 demonstrated that a mortality prime could be used to alter a health-related decision: the choice between a healthier food reward (fruit) and an unhealthy alternative (chocolate). Experiment 2 demonstrated that it is the controllability of the mortality risk being primed that generates the effect, rather than mortality risk per se. Experiment 3 showed that the effect could be seen in a surreptitious experiment that was not explicitly health related. Our results suggest that perceptions about the controllability of mortality risk may be an important factor in people's health-related decisions. Thus, techniques for adjusting perceptions about mortality risk could be important tools for use in health interventions. More importantly, tackling those sources of mortality that people perceive to be uncontrollable could have a dual purpose: making neighbourhoods and workplaces safer would have the primary benefit of reducing uncontrollable mortality risk, which could lead to a secondary benefit from improved health behaviours.

  15. Out of control mortality matters: the effect of perceived uncontrollable mortality risk on a health-related decision

    Directory of Open Access Journals (Sweden)

    Gillian V. Pepper

    2014-06-01

    Full Text Available Prior evidence from the public health literature suggests that both control beliefs and perceived threats to life are important for health behaviour. Our previously presented theoretical model generated the more specific hypothesis that uncontrollable, but not controllable, personal mortality risk should alter the payoff from investment in health protection behaviours. We carried out three experiments to test whether altering the perceived controllability of mortality risk would affect a health-related decision. Experiment 1 demonstrated that a mortality prime could be used to alter a health-related decision: the choice between a healthier food reward (fruit and an unhealthy alternative (chocolate. Experiment 2 demonstrated that it is the controllability of the mortality risk being primed that generates the effect, rather than mortality risk per se. Experiment 3 showed that the effect could be seen in a surreptitious experiment that was not explicitly health related. Our results suggest that perceptions about the controllability of mortality risk may be an important factor in people’s health-related decisions. Thus, techniques for adjusting perceptions about mortality risk could be important tools for use in health interventions. More importantly, tackling those sources of mortality that people perceive to be uncontrollable could have a dual purpose: making neighbourhoods and workplaces safer would have the primary benefit of reducing uncontrollable mortality risk, which could lead to a secondary benefit from improved health behaviours.

  16. Prevalence of Urinary Tract Infection and Antimicrobial Susceptibility among Diabetic Patients with Controlled and Uncontrolled Glycemia in Kuwait

    Directory of Open Access Journals (Sweden)

    May Sewify

    2016-01-01

    Full Text Available Diabetic patients have higher risk of urinary tract infection (UTI. In the present study, we investigated the impact of glycemic control in diabetic patients on UTI prevalence, type of strains, and their antimicrobial drugs susceptibility. This study was conducted on urine samples from 722 adult diabetic patients from which 252 (35% samples were positive for uropathogens. Most UTI cases occurred in the uncontrolled glycemic group (197 patients versus 55 patients with controlled glycemia. Higher glycemic levels were measured in uncontrolled glycemia group (HbA1c = 8.3 ± 1.5 and 5.4 ± 0.4, resp., P<0.0001. Females showed much higher prevalence of UTI than males in both glycemic groups (88.5% and 11.5%, resp., P<0.0001. In the uncontrolled glycemia group 90.9% of the UTI cases happened at ages above 40 years and a clear correlation was obtained between patient age ranges and number of UTI cases (r=0.94; P=0.017, whereas in the group with controlled glycemia no trend was observed. Escherichia coli was the predominant uropathogen followed by Klebsiella pneumoniae and they were together involved in 76.2% of UTI cases. Those species were similarly present in both diabetic groups and displayed comparable antibiotic resistance pattern. These results highlight the importance of controlling glycemia in diabetic patients to reduce the UTI regardless of age and gender.

  17. A randomised clinical trial of feedback on inhaler adherence and technique in patients with severe uncontrolled asthma.

    Science.gov (United States)

    Sulaiman, Imran; Greene, Garrett; MacHale, Elaine; Seheult, Jansen; Mokoka, Matshediso; D'Arcy, Shona; Taylor, Terence; Murphy, Desmond M; Hunt, Eoin; Lane, Stephen J; Diette, Gregory B; FitzGerald, J Mark; Boland, Fiona; Sartini Bhreathnach, Aoife; Cushen, Breda; Reilly, Richard B; Doyle, Frank; Costello, Richard W

    2018-01-01

    In severe asthma, poor control could reflect issues of medication adherence or inhaler technique, or that the condition is refractory. This study aimed to determine if an intervention with (bio)feedback on the features of inhaler use would identify refractory asthma and enhance inhaler technique and adherence.Patients with severe uncontrolled asthma were subjected to a stratified-by-site random block design. The intensive education group received repeated training in inhaler use, adherence and disease management. The intervention group received the same intervention, enhanced by (bio)feedback-guided training. The primary outcome was rate of actual inhaler adherence. Secondary outcomes included a pre-defined assessment of clinical outcome. Outcome assessors were blinded to group allocation. Data were analysed on an intention-to-treat and per-protocol basis.The mean rate of adherence during the third month in the (bio)feedback group (n=111) was higher than that in the enhanced education group (intention-to-treat, n=107; 73% versus 63%; 95% CI 2.8%-17.6%; p=0.02). By the end of the study, asthma was either stable or improved in 54 patients (38%); uncontrolled, but poorly adherent in 52 (35%); and uncontrolled, but adherent in 40 (27%).Repeated feedback significantly improved inhaler adherence. After a programme of adherence and inhaler technique assessment, only 40 patients (27%) were refractory and adherent, and might therefore need add-on therapy. Copyright ©ERS 2018.

  18. Diode laser cyclophotocoagulation paves way to a safer trabeculectomy in eyes with medically uncontrollable intraocular pressure.

    Science.gov (United States)

    Singh, Kirti; Dangda, Sonal; Ahir, Nitasha; Mutreja, Ankush; Bhattacharyya, Mainak

    2017-04-01

    High intraocular pressure (IOP) not responding to systemic and topical anti-glaucoma medications renders the eye at risk for both intra- and post-operative complications of glaucoma filtration surgery. Laser cyclophotocoagulation is able to lower IOP in such refractory glaucoma eyes and may make the surgical event safer. This study assessed diode laser cyclophotocoagulation (DLCP) when used as a temporary measure for lowering IOP prior to performing trabeculectomy. This study is a  retrospective analysis of cases planned for trabeculectomy surgery, uncontrolled on maximally tolerable systemic anti-glaucoma medications. They were analysed for response to DLCP in terms of IOP control, vision-related complications, increased inflammation, post-trabeculectomy hypotony and chances of phthisis and ciliary shutdown. Twelve eyes of ten patients aged 35-65 years were identified and all followed up for at least 2 years. One week following DLCP, the IOP (mean ± SD) declined by 51 % from 46.8 ± 5.4 to 22.8 ± 3.3 mmHg. The IOP was further reduced to 15.4 ± 2.7 mmHg at 4 weeks after trabeculectomy; it remained in the mid-teens for a minimum of 2 years in all cases. The mean (±SD) visual acuity improved from 1.4 ± 0.4 to 0.8 ± 0.4 LogMAR equivalents following trabeculectomy. In four eyes, phacoemulsification was performed 5-7 months after trabeculectomy with improvement in best-corrected visual acuity. One patient developed transient hypotony, post-trabeculectomy, which resolved by 6 days. There were no other complications like increased inflammation, prolonged hypotony or suprachoroidal haemorrhage. DLCP is, thus, effective and safe for temporarily controlling IOP; thereby trabeculectomy can be performed in a quieter ocular milieu.

  19. Uncontrollable behavior or mental illness? Exploring constructions of bulimia using Q methodology.

    Science.gov (United States)

    Churruca, Kate; Perz, Janette; Ussher, Jane M

    2014-01-01

    In medical and psychological literature bulimia is commonly described as a mental illness. However, from a social constructionist perspective the meaning of bulimia will always be socially and historically situated and multiple. Thus, there is always the possibility for other understandings or constructions of bulimia to circulate in our culture, with each having distinct real-world implications for those engaging in bulimic behaviors; for instance, they might potentially influence likelihood of help-seeking and the success of treatment. This study used Q methodology to explore culturally-available constructions of bulimia nervosa. Seventy-seven adults with varying experience of eating disorders took part in this Q methodological study. Online, they were asked to rank-order 42 statements about bulimia, and then answer a series of questions about the task and their knowledge of bulimia. A by-person factor analysis was then conducted, with factors extracted using the centroid technique and a varimax rotation. Six factors satisfied selection criteria and were subsequently interpreted. Factor A, "bulimia as uncontrolled behavior", positions bulimia as a behavioral rather than psychological issue. Factor B, entitled "bulimia is a distressing mental illness", reflects an understanding of bulimic behaviors as a dysfunctional coping mechanism, which is often found in psychological literature. Other perspectives position bulimia as about "self-medicating with food" (Factor C), "the pathological pursuit of thinness" (Factor D), "being the best at being thin" (Factor E), or as "extreme behavior vs. mentally ill" (Factor F). These constructions have distinct implications for the subjective experience and behavior of those engaged in bulimic behaviors, with some constructions possibly being more useful in terms of help-seeking (Factor B), while others position these individuals in ways that may be distressing, for instance as shallow (Factor D) or to blame (Factor E). This

  20. Prevalence of masked uncontrolled hypertension according to the number of office blood pressure measurements.

    Science.gov (United States)

    Vinyoles, E; Camafort, M; Domenech, M; Coca, A; Sobrino, J

    2015-11-01

    The reported prevalence of masked uncontrolled hypertension (MUCH) varies because many studies are not comparable as they use different measurement methodologies. To evaluate the influence of the number of office blood pressure readings on the prevalence of MUCH we conducted a cross-sectional, multicenter study in treated hypertensive patients. We carried out an observational, cross-sectional, multicenter study in 33 Spanish hospital-based hypertension units, involving 35 investigators and 12 Autonomous Communities. Six blood pressure readings and a 24-h ambulatory blood pressure monitoring were performed in treated hypertensive patients. The means of the first 3 readings (P123), the 2nd, 3rd and 4th readings (P234), the 3rd, 4th and 5th readings (P345) and the last 3 readings (P456) were compared with mean 24-h blood pressure. MUCH was defined as office blood pressure <140/90mmHg and 24-h blood pressure ≥130/80mmHg, considering the first 3 readings (MUCH123), the 2nd, 3rd and 4th readings (MUCH234), the 3rd, 4th and 5th readings (MUCH345) and the last 3 readings (MUCH456). We included 498 hypertensive patients. Mean (standard deviation) office blood pressure measurements were: (P123) 141(18)/82(11); (P234) 139(17)/81(11); (P345) 138(17)/81(11) and (P456) 137(16)/80(10) mmHg. Mean 24-h blood pressure was 127(13.8)/75(9.5) mmHg. The correlation coefficients between ambulatory and office systolic/diastolic blood pressure were (P123):0.48/0.50; (P234):0.50/0.52; (P345):0.50/0.54; and (P456):0.50/0.55 (p<0.001, all). The prevalences of MUCH123, MUCH234, MUCH345 and MUCH456 were 14.5%, 18.9%, 19.5% and 21.1%, respectively. The prevalence of MUCH diagnosis depends on the serial office blood pressure readings, being much higher for the last three blood pressure readings. Discarding the first and second office blood pressure measures seems to be the most accurate method for diagnosing MUCH. Copyright © 2015 Elsevier España, S.L.U. y Sociedad Española de Medicina

  1. Blood Pressure Control in Hypertensive Patients, Cardiovascular Risk Profile and the Prevalence of Masked Uncontrolled Hypertension (MUCH).

    Science.gov (United States)

    Naser, Nabil; Dzubur, Alen; Durak, Azra; Kulic, Mehmed; Naser, Nura

    2016-07-27

    The term masked hypertension (MH) should be used for untreated individuals who have normal office blood pressure but elevated ambulatory blood pressure. For treated patients, this condition should be termed masked uncontrolled hypertension (MUCH). Masked uncontrolled hypertension (MUCH) has gone unrecognized because few studies have used 24-h ABPM to determine the prevalence of suboptimal BP control in seemingly well-treated patients, and there are few such studies in large cohorts of treated patients attending usual clinical practice. This is important because masked hypertension is associated with a high risk of cardiovascular events. This study was conducted to obtain more information about the association between hypertension and other CV risk factors, about office and ambulatory blood pressure (BP) control as well as on cardiovascular (CV) risk profile in treated hypertensive patients, also to define the prevalence and characteristics of masked uncontrolled hypertension (MUCH) among treated hypertensive patients in routine clinical practice. In this study 2514 male and female patients were included during a period of 5 years follow up. All patients have ambulatory blood pressure monitoring (ABPM) for at least 24h. We identified patients with treated and controlled BP according to current international guidelines (clinic BP, 140/90mmHg). Cardiovascular risk assessment was based on personal history, clinic BP values, as well as target organ damage evaluation. Masked uncontrolled hypertension (MUCH) was diagnosed in these patients if despite controlled clinic BP, the mean 24-h ABPM average remained elevated (24-h systolic BP ≥130mmHg and/or 24-h diastolic BP ≥80mmHg). Patients had a mean age of 60.2+10 years, and the majority of them (94.6%) were followed by specialist physicians. Average clinic BP was 150.4+16/89.9+12 mmHg. About 70% of patients displayed a very high-risk profile. Ambulatory blood pressure monitoring (ABPM) was performed in all recruited

  2. Remote Sensing Information Gateway

    Science.gov (United States)

    Remote Sensing Information Gateway, a tool that allows scientists, researchers and decision makers to access a variety of multi-terabyte, environmental datasets and to subset the data and obtain only needed variables, greatly improving the download time.

  3. Remote handling equipment

    International Nuclear Information System (INIS)

    Clement, G.

    1984-01-01

    After a definition of intervention, problems encountered for working in an adverse environment are briefly analyzed for development of various remote handling equipments. Some examples of existing equipments are given [fr

  4. Hyperspectral remote sensing

    National Research Council Canada - National Science Library

    Eismann, Michael Theodore

    2012-01-01

    ..., and hyperspectral data processing. While there are many resources that suitably cover these areas individually and focus on specific aspects of the hyperspectral remote sensing field, this book provides a holistic treatment...

  5. The remote control system

    International Nuclear Information System (INIS)

    Jansweijer, P.P.M.

    1988-01-01

    The remote-control system is applied in order to control various signals in the car of the spectrometer at distance. The construction (hardware and software) as well as the operation of the system is described. (author). 20 figs

  6. Accessing Remote Knowledge

    DEFF Research Database (Denmark)

    Maskell, Peter

    2014-01-01

    young, single-site firms search for distant sources of complementary competences. The discussion is positioned within a comprehensive framework that allows a systematic investigation of the approaches available to firms engaged in globally extended learning. By utilizing the distinction between problem...... awareness (what remote knowledge is needed?) and source awareness (where does this knowledge reside?) the article explores the relative merits and inherent limitations of pipelines, listening posts, crowdsourcing and trade fairs to acquire knowledge and solutions from geographically and relationally remote...

  7. Remote maintenance development

    International Nuclear Information System (INIS)

    Zook, C.R.

    1979-01-01

    The concept of remote maintenance as it pertains to nuclear fuel fabrication facilities is quite unique. The future may require completely remote facilities where maintenance will be performed by hybrid manipulators/robots. These units will be capable of being preprogrammed for automatic operation or manually operated with the operator becoming a part of the closed loop control system. These robots will mesh television, computer control, and direct force feedback manual control in a usable new concept of robotics

  8. Training Helps Autistic Children Emerge from Solitude

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    Amother considers her child to be a continuation of her own life, and places her own desires that she cannot achieve on her child. A child is a mother’s sun, a mother’s hope. In this world, however, there exists another group of mothers whose children have autism. These children act as if they are completely alone, do not interact with others, and even refuse the love of

  9. One Hundred Years of Sociological Solitude?

    Science.gov (United States)

    Rumbaut, Ruben G.

    2005-01-01

    This Cuban-born author presents a narrative on the social events in the United States that marked his life as he embarked on a career in the field of sociology in the 1960s and 70s. He advocates for sociologists' awareness of social realities and the evolution of sociological studies from a socially-conscious perspective.

  10. One Hundred Years of Sociological Solitude?

    OpenAIRE

    Rumbaut, RG

    2005-01-01

    On the occasion of the American Sociological Association's centennial, The Chronicle asked seven sociologists to discuss what attracted them to the field, what they consider to be the discipline's fortes and failings, and where they'd like to see it go from here.

  11. Participation in a farmers' market fruit and vegetable prescription program at a federally qualified health center improves hemoglobin A1C in low income uncontrolled diabetics

    Directory of Open Access Journals (Sweden)

    Richard Bryce

    2017-09-01

    Access to a fruit and vegetable prescription program over a 13-week period led to decreased HbA1C concentrations in uncontrolled type 2 diabetic patients living in an urban area of predominately-lower socioeconomic status.

  12. THE ROLE OF METABOLIC SURGERY FOR PATIENTS WITH OBESITY GRADE I ANDCLINICALLY UNCONTROLLED TYPE 2 DIABETES.

    Science.gov (United States)

    Campos, Josemberg; Ramos, Almino; Szego, Thomaz; Zilberstein, Bruno; Feitosa, Heládio; Cohen, Ricardo

    2016-07-07

    Even considering the advance of the medical treatment in the last 20 years with new and more effective drugs, the outcomes are still disappointing as the control of obesity and type 2 Diabetes Mellitus (T2DM) with a large number of patients under the medical treatment still not reaching the desired outcomes. To present a Metabolic Risk Score to better guide the surgical indication for T2DM patients with body mass index (BMI) where surgery for obesity is still controversial. Research was conducted in PubMed, Medline, PubMed Central, Scielo and Lilacs between 2003-2015 correlating headings: metabolic surgery, obesity and type 2 diabetesmellitus. In addition, representatives of the societiesinvolved, as an expert panel, issued opinions. Forty-five related articles were analyzed by evidence-based medicine criteria. Grouped opinions sought to answer the following questions: Why metabolic and not bariatric surgery?; Mechanisms involved in glycemic control; BMI as a single criterion for surgical indication for uncontrolled T2DM; Results of metabolic surgery studies in BMIScielo e Lilacs entre 2003-2015 correlacionando os descritores:cirurgia metabólica, obesidade e diabete melito tipo 2. Adicionalmente, representantes das sociedades envolvidas emitiram opiniões em pontos nos quais não existia na literatura trabalhos com graus de evidência elevados. Foram encontrados 45 artigos relacionadosque foram analisados pelos critérios da medicina baseada em evidências.As opiniões agrupadas procuraram responder as seguintes questões: Porque cirurgia metabólica e não bariátrica?;Mecanismos envolvidos no controle glicêmico; IMC como critério isolado de indicação cirúrgica para o DMT2 não controlado; Resultados de estudos de cirurgia metabólica em IMC<35 kg/m2; Segurança da cirurgia metabólica em pacientes com IMC<35 kg/m2; Efeitos em longo prazo da cirurgia em pacientes com IMC inicial <35 kg/m2; Proposta de Escore de Risco Metabólico. A cirurgia metabólica tem

  13. A Systematic Review: Family Support Integrated with Diabetes Self-Management among Uncontrolled Type II Diabetes Mellitus Patients

    Directory of Open Access Journals (Sweden)

    Rian Adi Pamungkas

    2017-09-01

    Full Text Available The rate of type-2 diabetes mellitus (T2D is dramatically increasing worldwide. Continuing diabetes mellitus (DM care needs effective self-management education and support for both patients and family members. This study aimed to review and describe the impacts of diabetes mellitus self-management education (DSME that involve family members on patient outcomes related to patient health behaviors and perceived self-efficacy on self-management such as medication adherence, blood glucose monitoring, diet and exercise changes, health outcomes including psychological well-being and self-efficacy, and physiological markers including body mass index, level of blood pressure, cholesterol level and glycemic control. Three databases, PubMed, CINAHL, and Scopus were reviewed for relevant articles. The search terms were “type 2 diabetes,” “self-management,” “diabetes self-management education (DSME,” “family support,” “social support,” and “uncontrolled glycaemia.” Joanna Briggs Institute (JBI guidelines were used to determine which studies to include in the review. Details of the family support components of DSME intervention and the impacts of these interventions had on improving the health outcomes patients with uncontrolled glycaemia patients. A total of 22 intervention studies were identified. These studies involved different DSME strategies, different components of family support provided, and different health outcomes to be measured among T2D patients. Overall, family support had a positive impact on healthy diet, increased perceived support, higher self-efficacy, improved psychological well-being and better glycemic control. This systematic review found evidence that DSME with family support improved self-management behaviors and health outcomes among uncontrolled glycaemia T2D patients. The findings suggest DSME models that include family engagement can be a useful direction for improving diabetes care.

  14. A Systematic Review: Family Support Integrated with Diabetes Self-Management among Uncontrolled Type II Diabetes Mellitus Patients.

    Science.gov (United States)

    Pamungkas, Rian Adi; Chamroonsawasdi, Kanittha; Vatanasomboon, Paranee

    2017-09-15

    The rate of type-2 diabetes mellitus (T2D) is dramatically increasing worldwide. Continuing diabetes mellitus (DM) care needs effective self-management education and support for both patients and family members. This study aimed to review and describe the impacts of diabetes mellitus self-management education (DSME) that involve family members on patient outcomes related to patient health behaviors and perceived self-efficacy on self-management such as medication adherence, blood glucose monitoring, diet and exercise changes, health outcomes including psychological well-being and self-efficacy, and physiological markers including body mass index, level of blood pressure, cholesterol level and glycemic control. Three databases, PubMed, CINAHL, and Scopus were reviewed for relevant articles. The search terms were "type 2 diabetes," "self-management," "diabetes self-management education (DSME)," "family support," "social support," and "uncontrolled glycaemia." Joanna Briggs Institute (JBI) guidelines were used to determine which studies to include in the review. Details of the family support components of DSME intervention and the impacts of these interventions had on improving the health outcomes patients with uncontrolled glycaemia patients. A total of 22 intervention studies were identified. These studies involved different DSME strategies, different components of family support provided, and different health outcomes to be measured among T2D patients. Overall, family support had a positive impact on healthy diet, increased perceived support, higher self-efficacy, improved psychological well-being and better glycemic control. This systematic review found evidence that DSME with family support improved self-management behaviors and health outcomes among uncontrolled glycaemia T2D patients. The findings suggest DSME models that include family engagement can be a useful direction for improving diabetes care.

  15. Long-term treatment outcomes of acromegaly patients presenting biochemically-uncontrolled at a tertiary pituitary center.

    Science.gov (United States)

    Carmichael, John D; Broder, Michael S; Cherepanov, Dasha; Chang, Eunice; Mamelak, Adam; Said, Qayyim; Neary, Maureen P; Bonert, Vivien

    2017-08-04

    Acromegaly is a rare, slowly progressive disorder resulting from excessive growth hormone (GH) production by a pituitary somatotroph tumor. The objective of this study was to examine acromegaly treatment outcomes during long-term care at a specialized pituitary center in patients presenting with lack of biochemical control. Data came from an acromegaly registry at the Cedars-Sinai Medical Center Pituitary Center (center). Acromegaly patients included in this study were those who presented biochemically-uncontrolled for care at the center. Biochemical control status, based on serum insulin-like growth factor-1 values, was determined at presentation and at study end. Patient characteristics and acromegaly treatments were reported before and after presentation by presenting treatment status and final biochemical control status. Data on long-term follow-up were recorded from 1985 through June 2013. Seventy-four patients presented uncontrolled: 40 untreated (54.1%) and 34 (45.9%) previously-treated. Mean (SD) age at diagnosis was 43.2 (14.7); 32 (43.2%) were female patients. Of 65 patients with tumor size information, 59 (90.8%) had macroadenomas. Prior treatments among the 34 previously-treated patients were pituitary surgery alone (47.1%), surgery and medication (41.2%), and medication alone (11.8%). Of the 40 patients without prior treatment, 82.5% achieved control by study end. Of the 34 with prior treatment, 50% achieved control by study end. This observational study shows that treatment outcomes of biochemically-uncontrolled acromegaly patients improve with directed care, particularly for those that initially present untreated. Patients often require multiple modalities of treatment, many of which are offered with the highest quality at specialized pituitary centers. Despite specialized care, some patients were not able to achieve biochemical control with methods of treatment that were available at the time of their treatment, showing the need for additional

  16. [Effect of metabolic uncontrolled diabetes mellitus (DM) on the resistance index of renal (IR) Interlobar arteries assessed with pulsed Doppler].

    Science.gov (United States)

    Muraira-Cárdenas, Luis Cesar; Barrios-Pérez, Martín

    2016-01-01

    Diabetes mellitus is a chronic degenerative disease characterized by elevated hyperglycemia, triggering a series of processes and culminating in chronic, uncontrolled, cellular and vascular damage in different organs. To assess whether the elevated glycosylated hemoglobin, microalbuminuria, and the time evolution of more than 10 years of diabetes mellitus are associated with elevated resistance index of the interlobar renal arteries assessed with pulsed Doppler in patients with metabolic uncontrolled diabetes mellitus. Transversal-analytical, observational, prospective study that included diabetic patients attending UMAE abdominal ultrasound in 25 of IMSS, from October 15, 2014 to November 15, 2014, which was performed for pulsed Doppler index resistance of vascular interlobar renal arteries and was collected from electronic medical records: age, sex, glycated hemoglobin, and microalbuminuria. The association between metabolic uncontrolled diabetes mellitus was analyzed with the elevation of resistance index by χ(2) test or Fisher, being significant with a value of p diabetes were examined, with an average age of 52.3 ± 14.2 years, 41 were older than 50 years (65.0%), 26 with hypertension (41.2%), 32 with higher levels of glycated hemoglobin 7 (50.8%), 35 with normoalbuminuria (55.6%), 28 with microalbuminuria (44.4%), and 39 with a time evolution of diabetes of more than 10 years (61.9%). We observed a statistically significant difference between microalbuminuria and increased duration of diabetes mellitus with high resistance index. The alterations in renal microvasculature conditioned by the occurrence of microalbuminuria in diabetic nephropathy and the duration of diabetes are strongly associated with higher resistance index.

  17. Pulp necrosis following luxated injury to teeth in a patient with uncontrolled type II diabetes mellitus: a case report

    Directory of Open Access Journals (Sweden)

    Haneol Shin,

    2012-02-01

    Full Text Available Patients with diabetes mellitus show delayed wound healing and increased susceptibility to infection. Therefore, the effects of diabetes on pulpal and periodontal healing should be taken into consideration when treating diabetic dental traumatized patients. This case presents the treatment for dental traumatized 20 yr old female with uncontrolled type II diabetes. The traumatized upper central incisors had showed pulpal healing in early days. However, 7 mon after the trauma, the teeth had been diagnosed with pulp necrosis with apical abscess. Eventually, non surgical root canal treatment on the teeth had been performed.

  18. The Uncontrollable Mnemonic Fragments within Consciousness Reflecting Ophelia’s and Lady Macbeth’s Disturbed Minds

    Directory of Open Access Journals (Sweden)

    Ekmekçioğlu Neslihan

    2015-12-01

    Full Text Available Memory plays an important role in most of Shakespeare’s plays. Shakespeare delves into the dark realms of human consciousness to reflect the disturbed minds and gnawing consciences of his characters with a profound psychological insight into the human psyche. Time, memory, madness and death seem to be the basic issues dealt with in his canon. My paper will address the uncontrollable mnemonic fragments within the human consciousness which reflect past traumas, fears and disturbances and will examine the cases of Ophelia and Lady Macbeth from a feminist reading of women.

  19. Investigation of Intravenous Hydroxocobalamin Compared to Hextend for Resuscitation in a Swine Model of Uncontrolled Hemorrhagic Shock: A Preliminary Report

    Science.gov (United States)

    2017-06-16

    SSP in an uncontrolled...of at least 0.25 difference (1SO) in SSP between groups. Data were analyzed using repeated measures MANOVA. Data collection is ongoing...8217’" ,.."."-’ ,.,..",.,..’ ~.." / Time Results 6",," poll manu.JIl~..... 120minu •• niIMl -I I I I -- BL 81eecl.lMt SSP """’’’’Hg Applied e ..••• l ••• 1

  20. Remote connector development study

    International Nuclear Information System (INIS)

    Parazin, R.J.

    1995-05-01

    Plutonium-uranium extraction (PUREX) connectors, the most common connectors used at the Hanford site, offer a certain level of flexibility in pipe routing, process system configuration, and remote equipment/instrument replacement. However, these desirable features have inherent shortcomings like leakage, high pressure drop through the right angle bends, and a limited range of available pipe diameters that can be connect by them. Costs for construction, maintenance, and operation of PUREX connectors seem to be very high. The PUREX connector designs include a 90 degree bend in each connector. This increases the pressure drop and erosion effects. Thus, each jumper requires at least two 90 degree bends. PUREX connectors have not been practically used beyond 100 (4 in.) inner diameter. This study represents the results of a survey on the use of remote pipe-connection systems in US and foreign plants. This study also describes the interdependence between connectors, remote handling equipment, and the necessary skills of the operators

  1. Use of remote monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Fournel, E; Gouilloux, C

    1977-01-01

    Paper traces the development of remote monitoring devices, since their first appearance for safety purposes. Discusses their uses in coal mines: working and safety (definitions); sources and channels of information (transmission of information by automatic or verbal means); mine control stations; duties and responsibilities of persons in charge. Examines the contribution made by remote monitoring to management in production sector. Gives examples of assistance given to production management showing a very advantageous result on balance, by their use. The use of computers in real time and in batched mode is compared. Discusses their use in monitoring mine atmosphere. Very favorable results have already been obtained in France and abroad. The broadening scope and future of remote monitoring is considered.

  2. NET remote workstation

    International Nuclear Information System (INIS)

    Leinemann, K.

    1990-10-01

    The goal of this NET study was to define the functionality of a remote handling workstation and its hardware and software architecture. The remote handling workstation has to fulfill two basic functions: (1) to provide the man-machine interface (MMI), that means the interface to the control system of the maintenance equipment and to the working environment (telepresence) and (2) to provide high level (task level) supporting functions (software tools) during the maintenance work and in the preparation phase. Concerning the man-machine interface, an important module of the remote handling workstation besides the standard components of man-machine interfacing is a module for graphical scene presentation supplementing viewing by TV. The technique of integrated viewing is well known from JET BOOM and TARM control using the GBsim and KISMET software. For integration of equipment dependent MMI functions the remote handling workstation provides a special software module interface. Task level support of the operator is based on (1) spatial (geometric/kinematic) models, (2) remote handling procedure models, and (3) functional models of the equipment. These models and the related simulation modules are used for planning, programming, execution monitoring, and training. The workstation provides an intelligent handbook guiding the operator through planned procedures illustrated by animated graphical sequences. For unplanned situations decision aids are available. A central point of the architectural design was to guarantee a high flexibility with respect to hardware and software. Therefore the remote handling workstation is designed as an open system based on widely accepted standards allowing the stepwise integration of the various modules starting with the basic MMI and the spatial simulation as standard components. (orig./HP) [de

  3. Remote Reactor Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Bernstein, Adam [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dazeley, Steve [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dobie, Doug [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Marleau, Peter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brennan, Jim [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gerling, Mark [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sumner, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sweany, Melinda [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-21

    The overall goal of the WATCHMAN project is to experimentally demonstrate the potential of water Cerenkov antineutrino detectors as a tool for remote monitoring of nuclear reactors. In particular, the project seeks to field a large prototype gadolinium-doped, water-based antineutrino detector to demonstrate sensitivity to a power reactor at ~10 kilometer standoff using a kiloton scale detector. The technology under development, when fully realized at large scale, could provide remote near-real-time information about reactor existence and operational status for small operating nuclear reactors out to distances of many hundreds of kilometers.

  4. Remote sensing image fusion

    CERN Document Server

    Alparone, Luciano; Baronti, Stefano; Garzelli, Andrea

    2015-01-01

    A synthesis of more than ten years of experience, Remote Sensing Image Fusion covers methods specifically designed for remote sensing imagery. The authors supply a comprehensive classification system and rigorous mathematical description of advanced and state-of-the-art methods for pansharpening of multispectral images, fusion of hyperspectral and panchromatic images, and fusion of data from heterogeneous sensors such as optical and synthetic aperture radar (SAR) images and integration of thermal and visible/near-infrared images. They also explore new trends of signal/image processing, such as

  5. Introduction to remote sensing

    CERN Document Server

    Campbell, James B

    2012-01-01

    A leading text for undergraduate- and graduate-level courses, this book introduces widely used forms of remote sensing imagery and their applications in plant sciences, hydrology, earth sciences, and land use analysis. The text provides comprehensive coverage of principal topics and serves as a framework for organizing the vast amount of remote sensing information available on the Web. Including case studies and review questions, the book's four sections and 21 chapters are carefully designed as independent units that instructors can select from as needed for their courses. Illustrations in

  6. Radar Remote Sensing

    Science.gov (United States)

    Rosen, Paul A.

    2012-01-01

    This lecture was just a taste of radar remote sensing techniques and applications. Other important areas include Stereo radar grammetry. PolInSAR for volumetric structure mapping. Agricultural monitoring, soil moisture, ice-mapping, etc. The broad range of sensor types, frequencies of observation and availability of sensors have enabled radar sensors to make significant contributions in a wide area of earth and planetary remote sensing sciences. The range of applications, both qualitative and quantitative, continue to expand with each new generation of sensors.

  7. ENZYME-LINKED IMMUNOSORBENT ASSAY FOR SCREENING DIOXIN SOIL CONTAMINATION BY UNCONTROLLED COMBUSTION DURING INFORMAL RECYCLING IN SLUMS

    Science.gov (United States)

    Trindade, Mirta; Nording, Malin; Nichkova, Mikaela; Spinnel, Erik; Haglund, Peter; Last, Michael S.; Gee, Shirley; Hammock, Bruce; Last, Jerold A.; González-Sapienza, Gualberto; Brena, Beatriz M.

    2010-01-01

    Uncontrolled combustion due to garbage recycling is a widespread activity among slum dwellers in distressed economy countries and has been indicated as a major source of dioxin contamination. However, because of the high cost and complexity of gas chromatography/high-resolution mass spectrometry (GC-HRMS) analysis, the magnitude of the problem remains largely unknown. The present study describes a first approach toward the use of a dioxin antibody-based enzyme-linked immunosorbent assay (ELISA) as the basis for a sustainable, simple, and low-cost monitoring program to assess the toxicological impact of uncontrolled combustion in slums. A panel of 16 samples was analyzed by GC-HRMS and ELISA on split extracts. Close to 20% of the analyzed samples showed dioxin concentrations up to almost twice the guidance level for residential soil in several countries, pointing out the need for performing a large-scale monitoring program. Despite the potential for variations in dioxin congener distribution due to the mixed nature of the incinerated material, there was a good correlation between the toxic equivalents as determined by GC-HRMS and ELISA. Furthermore, an interlaboratory ELISA validation showed that the capacity to perform the dioxin ELISA was successfully transferred between laboratories. It was concluded that the ELISA method performed very well as a screening tool to prioritize samples for instrumental analysis, which allows cutting down costs significantly. PMID:18522475

  8. PresenceRemote

    DEFF Research Database (Denmark)

    Sokoler, Tomas; Svensson, Marcus Sanchez

    2008-01-01

    how these technologies can accommodate the specific challenges related to the everyday life of elderly people. In particular, using an example concept – the PresenceRemote – we will discuss how the stigma associated with being lonely, an inherent part of senior living, can be addressed by leaving room...

  9. A Remote WIRELESS Facility

    Directory of Open Access Journals (Sweden)

    Kees Uiterwijk

    2007-10-01

    Full Text Available Continuing need for available distance learning facilities has led to the development of a remote lab facility focusing on wireless technology. In the field of engineering there is a student need of gaining experience in set-up, monitoring and maintenance of 802.11A/B/G based wireless LAN environments.

  10. Remote sensing: best practice

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Gareth [Sgurr Energy (Canada)

    2011-07-01

    This paper presents remote sensing best practice in the wind industry. Remote sensing is a technique whereby measurements are obtained from the interaction of laser or acoustic pulses with the atmosphere. There is a vast diversity of tools and techniques available and they offer wide scope for reducing project uncertainty and risk but best practice must take into account versatility and flexibility. It should focus on the outcome in terms of results and data. However, traceability of accuracy requires comparison with conventional instruments. The framework for the Boulder protocol is given. Overviews of the guidelines for IEA SODAR and IEA LIDAR are also mentioned. The important elements of IEC 61400-12-1, an international standard for wind turbines, are given. Bankability is defined based on the Boulder protocol and a pie chart is presented that illustrates the uncertainty area covered by remote sensing. In conclusion it can be said that remote sensing is changing perceptions about how wind energy assessments can be made.

  11. Remote RF Battery Charging

    NARCIS (Netherlands)

    Visser, H.J.; Pop, V.; Op het Veld, J.H.G.; Vullers, R.J.M.

    2011-01-01

    The design of a remote RF battery charger is discussed through the analysis and design of the subsystems of a rectenna (rectifying antenna): antenna, rectifying circuit and loaded DC-to-DC voltage (buck-boost) converter. Optimum system power generation performance is obtained by adopting a system

  12. Section summary: Remote sensing

    Science.gov (United States)

    Belinda Arunarwati Margono

    2013-01-01

    Remote sensing is an important data source for monitoring the change of forest cover, in terms of both total removal of forest cover (deforestation), and change of canopy cover, structure and forest ecosystem services that result in forest degradation. In the context of Intergovernmental Panel on Climate Change (IPCC), forest degradation monitoring requires information...

  13. Remote Voice Detection System

    National Research Council Canada - National Science Library

    Blackmon, Fletcher A

    2007-01-01

    A device and system to remotely detect vocalizations of speech. The skin located on the throat region of a speaking person or a reflective layer on the skin on the throat region vibrates in response to vocalizations of speech by the person...

  14. Remotely controlled spray gun

    Science.gov (United States)

    Cunningham, William C. (Inventor)

    1987-01-01

    A remotely controlled spray gun is described in which a nozzle and orifice plate are held in precise axial alignment by an alignment member, which in turn is held in alignment with the general outlet of the spray gun by insert. By this arrangement, the precise repeatability of spray patterns is insured.

  15. Remote sensing for water quality

    International Nuclear Information System (INIS)

    Giardino, Claudia

    2006-01-01

    The application of remote sensing to the study of lakes is begun in years 80 with the lunch of the satellites of second generation. Many experiences have indicated the contribution of remote sensing for the limnology [it

  16. Time-sensitive remote sensing

    CERN Document Server

    Lippitt, Christopher; Coulter, Lloyd

    2015-01-01

    This book documents the state of the art in the use of remote sensing to address time-sensitive information requirements. Specifically, it brings together a group of authors who are both researchers and practitioners, who work toward or are currently using remote sensing to address time-sensitive information requirements with the goal of advancing the effective use of remote sensing to supply time-sensitive information. The book addresses the theoretical implications of time-sensitivity on the remote sensing process, assessments or descriptions of methods for expediting the delivery and improving the quality of information derived from remote sensing, and describes and analyzes time-sensitive remote sensing applications, with an emphasis on lessons learned. This book is intended for remote sensing scientists, practitioners (e.g., emergency responders or administrators of emergency response agencies), and students, but will also be of use to those seeking to understand the potential of remote sensing to addres...

  17. Remote Sensing and the Earth.

    Science.gov (United States)

    Brosius, Craig A.; And Others

    This document is designed to help senior high school students study remote sensing technology and techniques in relation to the environmental sciences. It discusses the acquisition, analysis, and use of ecological remote data. Material is divided into three sections and an appendix. Section One is an overview of the basics of remote sensing.…

  18. The SGLT2 Inhibitor Dapagliflozin Significantly Improves the Peripheral Microvascular Endothelial Function in Patients with Uncontrolled Type 2 Diabetes Mellitus.

    Science.gov (United States)

    Sugiyama, Seigo; Jinnouchi, Hideaki; Kurinami, Noboru; Hieshima, Kunio; Yoshida, Akira; Jinnouchi, Katsunori; Nishimura, Hiroyuki; Suzuki, Tomoko; Miyamoto, Fumio; Kajiwara, Keizo; Jinnouchi, Tomio

    2018-03-30

    Objective Sodium-glucose cotransporter-2 (SGLT2) inhibitors reduce cardiovascular events and decrease the body fat mass in patients with type 2 diabetes mellitus (T2DM). We examined whether or not the SGLT2-inhibitor dapagliflozin can improve the endothelial function associated with a reduction in abdominal fat mass. Methods We prospectively recruited patients with uncontrolled (hemoglobin A1c [HbA1c] >7.0%) T2DM who were not being treated by SGLT2 inhibitors. Patients were treated with add-on dapagliflozin (5 mg/day) or non-SGLT2 inhibitor medicines for 6 months to improve their HbA1c. We measured the peripheral microvascular endothelial function as assessed by reactive hyperemia peripheral arterial tonometry (RH-PAT) and calculated the natural logarithmic transformed value of the RH-PAT index (LnRHI). We then investigated changes in the LnRHI and abdominal fat area using computed tomography (CT). Results The subjects were 54 patients with uncontrolled T2DM (72.2% men) with a mean HbA1c of 8.1%. The HbA1c was significantly decreased in both groups, with no significant difference between the groups. Dapagliflozin treatment, but not non-SGLT2 inhibitor treatment, significantly increased the LnRHI. The changes in the LnRHI were significantly greater in the dapagliflozin group than in the non-SGLT2 inhibitor group. Dapagliflozin treatment, but not non-SGLT2 inhibitor treatment, significantly decreased the abdominal visceral fat area, subcutaneous fat area (SFA), and total fat area (TFA) as assessed by CT and significantly increased the plasma adiponectin levels. The percentage changes in the LnRHI were significantly correlated with changes in the SFA, TFA, systolic blood pressure, and adiponectin. Conclusion Add-on treatment with dapagliflozin significantly improves the glycemic control and endothelial function associated with a reduction in the abdominal fat mass in patients with uncontrolled T2DM.

  19. Remote maintenance development for ITER

    International Nuclear Information System (INIS)

    Tada, Eisuke; Shibanuma, Kiyoshi

    1998-01-01

    This paper describes the overall ITER remote maintenance design concept developed mainly for in-vessel components such as diverters and blankets, and outlines the ITER R and D program to develop remote handling equipment and radiation hard components. Reactor structures inside the ITER cryostat must be maintained remotely due to DT operation, making remote handling technology basic to reactor design. The overall maintenance scenario and design concepts have been developed, and maintenance design feasibility, including fabrication and testing of full-scale in-vessel remote maintenance handling equipment and tool, is being verified. (author)

  20. Remote maintenance development for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Tada, Eisuke [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Shibanuma, Kiyoshi

    1998-04-01

    This paper describes the overall ITER remote maintenance design concept developed mainly for in-vessel components such as diverters and blankets, and outlines the ITER R and D program to develop remote handling equipment and radiation hard components. Reactor structures inside the ITER cryostat must be maintained remotely due to DT operation, making remote handling technology basic to reactor design. The overall maintenance scenario and design concepts have been developed, and maintenance design feasibility, including fabrication and testing of full-scale in-vessel remote maintenance handling equipment and tool, is being verified. (author)

  1. Remote monitoring demonstration

    International Nuclear Information System (INIS)

    Caskey, Susan; Olsen, John

    2006-01-01

    The recently upgraded remote monitoring system at the Joyo Experimental Reactor uses a DCM-14 camera module and GEMINI software. The final data is compatible both with the IAEA-approved GARS review software and the ALIS software that was used for this demonstration. Features of the remote monitoring upgrade emphasized compatibility with IAEA practice. This presentation gives particular attention to the selection process for meeting network security considerations at the O'arai site. The Joyo system is different from the NNCA's ACPF system, in that it emphasizes use of IAEA standard camera technology and data acquisition and transmission software. In the demonstration itself, a temporary virtual private network (VPN) between the meeting room and the server at Sandia in Albuquerque allowed attendees to observe data stored from routine transmissions from the Joyo Fresh Fuel Storage to Sandia. Image files from a fuel movement earlier in the month showed Joyo workers and IAEA inspectors carrying out a transfer. (author)

  2. RemoteLabs Platform

    Directory of Open Access Journals (Sweden)

    Nils Crabeel

    2012-03-01

    Full Text Available This paper reports on a first step towards the implementation of a framework for remote experimentation of electric machines – the RemoteLabs platform. This project was focused on the development of two main modules: the user Web-based and the electric machines interfaces. The Web application provides the user with a front-end and interacts with the back-end – the user and experiment persistent data. The electric machines interface is implemented as a distributed client server application where the clients, launched by the Web application, interact with the server modules located in platforms physically connected the electric machines drives. Users can register and authenticate, schedule, specify and run experiments and obtain results in the form of CSV, XML and PDF files. These functionalities were successfully tested with real data, but still without including the electric machines. This inclusion is part of another project scheduled to start soon.

  3. Recruiting in remote locations

    Energy Technology Data Exchange (ETDEWEB)

    Ionel, C. [Enerflex Systems Ltd., Calgary, AB (Canada)

    2006-07-01

    This presentation provided details of Enerflex, a leading supplier of products and services to the oil and gas industry, and outlined their personnel hiring policies. Enerflex's core values include community involvement and divisional logo branding. The extensive training that is provided places an emphasis on employee empowerment. The company also places an emphasis on employee safety, diversity, and team building. Competitive salaries are offered along with generous equipment allowances and a flexible benefits program. Benefits include travel and overtime rates; health benefits; retirement savings; scholarship programs; career opportunities; and apprenticeship programs. External technical training is provided. An employee referral program has been developed, and the company's recruitment program also advertises in remote newspapers to develop career streams within remote communities. tabs., figs.

  4. Remote handling in ZEPHYR

    International Nuclear Information System (INIS)

    Andelfinger, C.; Lackner, E.; Ulrich, M.; Weber, G.; Schilling, H.B.

    1982-04-01

    A conceptual design of the ZEPHYR building is described. The listed radiation data show that remote handling devices will be necessary in most areas of the building. For difficult repair and maintenance works it is intended to transfer complete units from the experimental hall to a hot cell which provides better working conditions. The necessary crane systems and other transport means are summarized as well as suitable commercially available manipulators and observation devices. The conept of automatic devices for cutting and welding and other operations inside the vacuum vessel and the belonging position control system is sketched. Guidelines for the design of passive components are set up in order to facilitate remote operation. (orig.)

  5. Remote Ischemic Conditioning

    Science.gov (United States)

    Heusch, Gerd; Bøtker, Hans Erik; Przyklenk, Karin; Redington, Andrew; Yellon, Derek

    2014-01-01

    In remote ischemic conditioning (RIC) brief, reversible episodes of ischemia with reperfusion in one vascular bed, tissue or organ confer a global protective phenotype and render remote tissues and organs resistant to ischemia/reperfusion injury. The peripheral stimulus can be chemical, mechanical or electrical and involves activation of peripheral sensory nerves. The signal transfer to the heart or other organs is through neuronal and humoral communications. Protection can be transferred, even across species, with plasma-derived dialysate and involves nitric oxide, stromal derived factor-1α, microRNA-144, but also other, not yet identified factors. Intracardiac signal transduction involves: adenosine, bradykinin, cytokines, and chemokines, which activate specific receptors; intracellular kinases; and mitochondrial function. RIC by repeated brief inflation/deflation of a blood pressure cuff protects against endothelial dysfunction and myocardial injury in percutaneous coronary interventions, coronary artery bypass grafting and reperfused acute myocardial infarction. RIC is safe and effective, noninvasive, easily feasible and inexpensive. PMID:25593060

  6. Does Market Remoteness Matter?

    OpenAIRE

    Moctar, Ndiaye; Elodie, Maitre d’Hôtel; Tristan, Le Cotty

    2015-01-01

    This paper addresses the role of market remoteness in explaining maize price volatility in Burkina Faso. A model of price formation is introduced to demonstrate formally that transport costs between urban and rural markets exacerbate maize price volatility. Empirical support is provided to the proposition by exploring an unusually rich data set of monthly maize price series across 28 markets over 2004-13. The methodology relies on an autoregressive conditional heteroskedasticity model to inve...

  7. Remote entanglement distribution

    International Nuclear Information System (INIS)

    Sanders, B.C.; Gour, G.; Meyer, D.A.

    2005-01-01

    Full text: Shared bipartite entanglement is a crucial shared resource for many quantum information tasks such as teleportation, entanglement swapping, and remote state preparation. In general different nodes of a quantum network share an entanglement resource, such as ebits, that are consumed during the task. In practice, generating entangled states is expensive, but here we establish a protocol by which a quantum network requires only a single supplier of entanglement to all nodes who, by judicious measurements and classical communication, provides the nodes with a unique pair wise entangled state independent of the measurement outcome. Furthermore, we extend this result to a chain of suppliers and nodes, which enables an operational interpretation of concurrence. In the special case that the supplier shares bipartite states with two nodes, and such states are pure and maximally entangled, our protocol corresponds to entanglement swapping. However, in the practical case that initial shared entanglement between suppliers and nodes involves partially entangled or mixed states, we show that general local operations and classical communication by all parties (suppliers and nodes) yields distributions of entangled states between nodes. In general a distribution of bipartite entangled states between any two nodes will include states that do not have the same entanglement; thus we name this general process remote entanglement distribution. In our terminology entanglement swapping with partially entangled states is a particular class of remote entanglement distribution protocols. Here we identify which distributions of states that can or cannot be created by remote entanglement distribution. In particular we prove a powerful theorem that establishes an upper bound on the entanglement of formation that can be produced between two qubit nodes. We extend this result to the case of a linear chain of parties that play the roles of suppliers and nodes; this extension provides

  8. Remote earth sensing experiments

    Energy Technology Data Exchange (ETDEWEB)

    Trifonov, Yu V

    1981-01-01

    Description of data devices for deriving multi-spectral measuring television measurement data of middle and high resolution through use of second generation Meteor-type satellites. Options for developing a permanent and active remote sensing system in USSR are discussed. It is noted that the present experiment is an important step in that direction. Design and structural data for this particular device and its application in the experiment are covered.

  9. Remote maintenance development for ITER

    International Nuclear Information System (INIS)

    Tada, Eisuke; Shibanuma, Kiyoshi

    1997-01-01

    This paper both describes the overall design concept of the ITER remote maintenance system, which has been developed mainly for use with in-vessel components such as divertor and blanket, and outlines of the ITER R and D program, which has been established to develop remote handling equipment/tools and radiation hard components. In ITER, the reactor structures inside cryostat have to be maintained remotely because of activation due to DT operation. Therefore, remote-handling technology is fundamental, and the reactor-structure design must be made consistent with remote maintainability. The overall maintenance scenario and design concepts of the required remote handling equipment/tools have been developed according to their maintenance classification. Technologies are also being developed to verify the feasibility of the maintenance design and include fabrication and testing of a fullscale remote-handling equipment/tools for in-vessel maintenance. (author)

  10. Low-dose spinal-epidural anesthesia for Cesarean section in a parturient with uncontrolled hyperthyroidism and thyrotoxic heart disease.

    Science.gov (United States)

    Liao, Zhimin; Xiong, Yaqin; Luo, Linli

    2016-08-01

    A 29-year-old woman at 34 weeks' gestation with uncontrolled hyperthyroidism and thyrotoxic heart disease was admitted to urgency Cesarean section. After preoperative sedation and good communication, low-dose spinal anesthesia (7.5 mg 0.5 % bupivacaine) combined with epidural anesthesia (6 ml 2 % lidocaine) was performed through L3-4 inter-vertebral. Opioids were given intravenously to the mother for sedation after delivery of the baby. Satisfactory anesthesia and sedation was provided during surgery. The mother and the neonate were safe and no special complication was found after surgery. Our case demonstrated that low-dose spinal anesthesia combined with epidural anesthesia with intravenous opioids can provide satisfactory anesthesia and sedation, and reduce the risk of heart failure and thyroid storm.

  11. Hopf bifurcation and uncontrolled stochastic traffic-induced chaos in an RED-AQM congestion control system

    International Nuclear Information System (INIS)

    Wang Jun-Song; Yuan Rui-Xi; Gao Zhi-Wei; Wang De-Jin

    2011-01-01

    We study the Hopf bifurcation and the chaos phenomena in a random early detection-based active queue management (RED-AQM) congestion control system with a communication delay. We prove that there is a critical value of the communication delay for the stability of the RED-AQM control system. Furthermore, we show that the system will lose its stability and Hopf bifurcations will occur when the delay exceeds the critical value. When the delay is close to its critical value, we demonstrate that typical chaos patterns may be induced by the uncontrolled stochastic traffic in the RED-AQM control system even if the system is still stable, which reveals a new route to the chaos besides the bifurcation in the network congestion control system. Numerical simulations are given to illustrate the theoretical results. (general)

  12. Dramatic course of osteomyelitis in a patient treated with immediately placed dental implants suffering from uncontrolled diabetes: A case report.

    Science.gov (United States)

    Doll, Christian; Hartwig, Stefan; Nack, Claudia; Nahles, Susanne; Nelson, Katja; Raguse, Jan-Dirk

    2015-01-01

    To report a rare and dramatic complication following immediate dental implant placement in a heavy smoker, who had a delayed diagnosis of uncontrolled diabetes. In this case report we present the dramatic course of a 64-year old female patient treated with five immediate post-extractive dental implants in the mandible, who developed osteomyelitis, which manifested initially as local peri-implant inflammation and progressed into a spontaneous jaw fracture, despite repeated surgical interventions and antibiotic courses over a 3-year period, until diabetes was diagnosed. A symptom-free status could be achieved only after partial mandibulectomy, treatment of diabetes and reconstruction with a microvascular fibula free flap. In the presence of mandibular osteomyelitis refractory to therapy, yet undiagnosed underlying pathologies, such as diabetes, should be investigated and treated urgently.

  13. Efficacy of Prompt Initiation of Antiretroviral Therapy in the Treatment of Hemophagocytic Lymphohistiocytosis Triggered by Uncontrolled Human Immunodeficiency Virus

    Directory of Open Access Journals (Sweden)

    Bryan P. Fitzgerald

    2017-01-01

    Full Text Available Hemophagocytic lymphohistiocytosis (HLH is a life-threatening, rapidly progressive hematologic disorder involving uncontrolled immune system activation. HLH has been associated with viral infections, including human immunodeficiency virus (HIV infections. We report a case of a critically ill 30-year-old female who was hospitalized with HIV-associated HLH, with a CD4 count of 4 cells/mL and HIV viral load of 1,842,730 copies/mL. After ruling out other potential infectious causes of HLH, antiretroviral therapy (ART was initiated with darunavir, ritonavir, tenofovir, and emtricitabine. Within one week of initiation of ART, the patient began to improve clinically and hematologically and was stable enough for discharge from the hospital three weeks after starting therapy. This case suggests that treatment with ART in patients with HIV-associated HLH should be considered even in critically ill patients with low CD4 counts.

  14. Remote repair appliance

    International Nuclear Information System (INIS)

    Heumann, F.K.; Wilkinson, J.C.; Wooding, D.R.

    1997-01-01

    A remote appliance for supporting a tool for performing work at a work site on a substantially circular bore of a work piece and for providing video signals of the work site to a remote monitor comprises: a base plate having an inner face and an outer face; a plurality of rollers, wherein each roller is rotatably and adjustably attached to the inner face of the base plate and positioned to roll against the bore of the work piece when the base plate is positioned against the mouth of the bore such that the appliance may be rotated about the bore in a plane substantially parallel to the base plate; a tool holding means for supporting the tool, the tool holding means being adjustably attached to the outer face of the base plate such that the working end of the tool is positioned on the inner face side of the base plate; a camera for providing video signals of the work site to the remote monitor; and a camera holding means for supporting the camera on the inner face side of the base plate, the camera holding means being adjustably attached to the outer face of the base plate. In a preferred embodiment, roller guards are provided to protect the rollers from debris and a bore guard is provided to protect the bore from wear by the rollers and damage from debris. 5 figs

  15. Modular remote radiation monitor

    International Nuclear Information System (INIS)

    Lacerda, Fabio; Farias, Marcos S.; Aghina, Mauricio A.C.; Oliveira, Mauro V.

    2013-01-01

    The Modular Remote Radiation Monitor (MRRM) is a novel radiation monitor suitable for monitoring environmental exposure to ionizing radiation. It is a portable compact-size low-power microprocessor-based electronic device which provides its monitoring data to other electronic systems, physically distant from it, by means of an electronic communication channel, which can be wired or wireless according to the requirements of each application. Besides its low-power highly-integrated circuit design, the Modular Remote Radiation Monitor is presented in a modular architecture, which promotes full compliance to the technical requirements of different applications while minimizing cost, size and power consumption. Its communication capability also supports the implementation of a network of multiple radiation monitors connected to a supervisory system, capable of remotely controlling each monitor independently as well as visualizing the radiation levels from all monitors. A prototype of the MRRM, functionally equivalent to the MRA-7027 radiation monitor, was implemented and connected to a wired MODBUS network of MRA-7027 monitors, responsible for monitoring ionizing radiation inside Argonauta reactor room at Instituto de Engenharia Nuclear. Based on the highly positive experimental results obtained, further design is currently underway in order to produce a consumer version of the MRRM. (author)

  16. Subsurface remote sensing

    International Nuclear Information System (INIS)

    Schweitzer, Jeffrey S.; Groves, Joel L.

    2002-01-01

    Subsurface remote sensing measurements are widely used for oil and gas exploration, for oil and gas production monitoring, and for basic studies in the earth sciences. Radiation sensors, often including small accelerator sources, are used to obtain bulk properties of the surrounding strata as well as to provide detailed elemental analyses of the rocks and fluids in rock pores. Typically, instrument packages are lowered into a borehole at the end of a long cable, that may be as long as 10 km, and two-way data and instruction telemetry allows a single radiation instrument to operate in different modes and to send the data to a surface computer. Because these boreholes are often in remote locations throughout the world, the data are frequently transmitted by satellite to various locations around the world for almost real-time analysis and incorporation with other data. The complete system approach that permits rapid and reliable data acquisition, remote analysis and transmission to those making decisions is described

  17. Evaluation of an mHealth Medication Regimen Self-Management Program for African American and Hispanic Uncontrolled Hypertensives

    Directory of Open Access Journals (Sweden)

    Tatiana M. Davidson

    2015-11-01

    Full Text Available African Americans and Hispanics have disproportionate rates of uncontrolled essential hypertension (EH compared to Non-Hispanic Whites. Medication non-adherence (MNA is the leading modifiable behavior to improved blood pressure (BP control. The Smartphone Medication Adherence Stops Hypertension (SMASH program was developed using a patient-centered, theory-guided, iterative design process. Electronic medication trays provided reminder signals, and Short Message Service [SMS] messaging reminded subjects to monitor BP with Bluetooth-enabled monitors. Motivational and reinforcement text messages were sent to participants based upon levels of adherence. Thirty-eight African-American (18 and Hispanic (20 uncontrolled hypertensives completed clinic-based anthropometric and resting BP evaluations prior to randomization, and again at months 1, 3 and 6. Generalized linear mixed modeling (GLMM revealed statistically significant time-by-treatment interactions (p < 0.0001 indicating significant reductions in resting systolic blood pressure (SBP and diastolic blood pressure (DBP for the SMASH group vs. the standard care (SC control group across all time points. 70.6% of SMASH subjects vs. 15.8% of the SC group reached BP control (< 140/90 mmH at month 1 (p < 0.001. At month 6, 94.4% of the SMASH vs. 41.2% of the SC group exhibited controlled BP (p < 0.003. Our findings provide encouraging evidence that efficacious mHealth, chronic disease, medical regimen, self-management programs can be developed following principles of patient-centered, theory-guided design.

  18. Effects of Vildagliptin Add-on Insulin Therapy on Nocturnal Glycemic Variations in Uncontrolled Type 2 Diabetes.

    Science.gov (United States)

    Li, Feng-Fei; Shen, Yun; Sun, Rui; Zhang, Dan-Feng; Jin, Xing; Zhai, Xiao-Fang; Chen, Mao-Yuan; Su, Xiao-Fei; Wu, Jin-Dan; Ye, Lei; Ma, Jian-Hua

    2017-10-01

    To investigate whether vildagliptin add-on insulin therapy improves glycemic variations in patients with uncontrolled type 2 diabetes (T2D) compared to patients with placebo therapy. This was a 24-week, single-center, double-blind, placebo-controlled trial. Inadequately controlled T2D patients treated with insulin therapy were recruited between June 2012 and April 2013. The trial included a 2-week screening period and a 24-week randomized period. Subjects were randomly assigned to a vildagliptin add-on insulin therapy group (n = 17) or a matched placebo group (n = 16). Scheduled visits occurred at weeks 4, 8, 12, 16, 20, and 24. Continuous glucose monitoring (CGM) was performed before and at the endpoint of the study. A total of 33 subjects were admitted, with 1 patient withdrawing from the placebo group. After 24 weeks of therapy, HbA1c values were significantly reduced at the endpoint in the vildagliptin add-on group. CGM data showed that patients with vildagliptin add-on therapy had a significantly lower 24-h mean glucose concentration and mean amplitude of glycemic excursion (MAGE). At the endpoint of the study, patients in the vildagliptin add-on group had a significantly lower MAGE and standard deviation compared to the control patients during the nocturnal period (0000-0600). A severe hypoglycemic episode was not observed in either group. Vildagliptin add-on therapy to insulin has the ability to improve glycemic variations, especially during the nocturnal time period, in patients with uncontrolled T2D.

  19. PRIMARY RESULTS OF LONG-TERM DYNAMIC MONITORING OF CHILDREN WITH BRONCHIAL ASTHMA OF UNCONTROLLED SEVERE PERSISTENT COURSE

    Directory of Open Access Journals (Sweden)

    L. S. Namazova-Baranova

    2016-01-01

    Full Text Available Background. Patients registers help obtain the latest information about the clinical course of a disease, safety and effectiveness of the medical technology. Objective: Our aim was to analyze the efficiency and safety of omalizumab with children suffering from uncontrolled severe persistent bronchial asthma (BA according to the data of the developed register. Methods.  A register of patients with severe asthma of uncontrolled course receiving omalizumab in addition to basic therapy has been developed. Results. Results of treatment of 101 children aged 6–17 have been analyzed. The duration of therapy with omalizumab lasted from 1 to 85 months, with a median of 16 (10; 44 months. The drug was used in doses of 75 to 600 mg, with a median of 300 (225; 375 mg. The therapy with omalizumab allowed achieving a better control of the disease (AST test prior to start of therapy — 14 (11; 17 points, in 1 year — 20 (13; 25; p < 0,001; reduction of the volume of daily base therapy (prior to start of therapy, average dose of inhaled corticosteroids in terms of fluticasone was 629 ± 304 mg (n = 15, in 4 years — 524 ± 342 mg; p = 0.065; reduction of the number of aggravations and the need to use short-effectiv   2-agonists.  No adverse systemic effects of the introduction of genetically engineered biological drugs have been found. Conclusion. Register of patients with severe persistent asthma can be used as a tool for long-term  monitoring and integrated assessment of the efficiency and safety of therapy.

  20. Running Reduces Uncontrollable Stress-Evoked Serotonin and Potentiates Stress-Evoked Dopamine Concentrations in the Rat Dorsal Striatum.

    Directory of Open Access Journals (Sweden)

    Peter J Clark

    Full Text Available Accumulating evidence from both the human and animal literature indicates that exercise reduces the negative consequences of stress. The neurobiological etiology for this stress protection, however, is not completely understood. Our lab reported that voluntary wheel running protects rats from expressing depression-like instrumental learning deficits on the shuttle box escape task after exposure to unpredictable and inescapable tail shocks (uncontrollable stress. Impaired escape behavior is a result of stress-sensitized serotonin (5-HT neuron activity in the dorsal raphe (DRN and subsequent excessive release of 5-HT into the dorsal striatum following exposure to a comparatively mild stressor. However, the possible mechanisms by which exercise prevents stress-induced escape deficits are not well characterized. The purpose of this experiment was to test the hypothesis that exercise blunts the stress-evoked release of 5-HT in the dorsal striatum. Changes to dopamine (DA levels were also examined, since striatal DA signaling is critical for instrumental learning and can be influenced by changes to 5-HT activity. Adult male F344 rats, housed with or without running wheels for 6 weeks, were either exposed to tail shock or remained undisturbed in laboratory cages. Twenty-four hours later, microdialysis was performed in the medial (DMS and lateral (DLS dorsal striatum to collect extracellular 5-HT and DA before, during, and following 2 mild foot shocks. We report wheel running prevents foot shock-induced elevation of extracellular 5-HT and potentiates DA concentrations in both the DMS and DLS approximately 24 h following exposure to uncontrollable stress. These data may provide a possible mechanism by which exercise prevents depression-like instrumental learning deficits following exposure to acute stress.

  1. Assessing the impact of a remote digital coaching engagement program on patient-reported outcomes in asthma.

    Science.gov (United States)

    Rasulnia, Mazi; Burton, Billy Stephen; Ginter, Robert P; Wang, Tracy Y; Pleasants, Roy Alton; Green, Cynthia L; Lugogo, Njira

    2017-08-11

    Low adherence and poor outcomes provide opportunity for digital coaching to engage patients with uncontrolled asthma in their care to improve outcomes. To examine the impact of a remote digital coaching program on asthma control and patient experience. We recruited 51 adults with uncontrolled asthma, denoted by albuterol use of >2 times per week and/or exacerbations requiring corticosteroids, and applied a 12-week patient-centered remote digital coaching program using a combination of educational pamphlets, symptom trackers, best peak flow establishment, physical activity, and dietary counseling, as well as coaches who implemented emotional enforcement to motivate disease self-management through telephone, text, and email. Baseline and post-intervention measures were quality of life (QOL), spirometry, Asthma Control Test (ACT), Asthma Symptom Utility Index (ASUI), rescue albuterol use, and exacerbation history. Among 51 patients recruited, 40 completed the study. Eight subjects required assistance reading medical materials. Significant improvements from baseline were observed for Patient-Reported Outcomes Measurement Information System mental status (p = 0.010), body weight, and outpatient exacerbation frequency (p = 0.028). The changes from baseline in ACT (p = 0.005) were statistically significant but did not achieve the pre-specified minimum clinically important difference (MCID), whereas for ASUI, the MCID and statistical significance were achieved. Spirometry and rescue albuterol use were no different. A patient-oriented, remote digital coaching program that utilized trained health coaches and digital materials led to statistically significant improvement in mental status, outpatient exacerbations, body weight, and ASUI. Digital coaching programs may improve some outcomes in adults with uncontrolled asthma.

  2. Remotely controllable liquid marbles

    KAUST Repository

    Zhang, Lianbin

    2012-07-26

    Liquid droplets encapsulated by self-organized hydrophobic particles at the liquid/air interface - liquid marbles - are prepared by encapsulating water droplets with novel core/shell-structured responsive magnetic particles, consisting of a responsive block copolymer-grafted mesoporous silica shell and magnetite core (see figure; P2VP-b-PDMS: poly(2-vinylpyridine-b- dimethylsiloxane)). Desirable properties of the liquid marbles include that they rupture upon ultraviolet illumination and can be remotely manipulated by an external magnetic field. 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Remote Sensing for Wind Energy

    DEFF Research Database (Denmark)

    Peña, Alfredo; Hasager, Charlotte Bay; Lange, Julia

    The Remote Sensing in Wind Energy report provides a description of several topics and it is our hope that students and others interested will learn from it. The idea behind it began in year 2008 at DTU Wind Energy (formerly Risø) during the first PhD Summer School: Remote Sensing in Wind Energy...... state-of-the-art ‘guideline’ available for people involved in Remote Sensing in Wind Energy....

  4. Remote Sensing for Wind Energy

    DEFF Research Database (Denmark)

    The Remote Sensing in Wind Energy Compendium provides a description of several topics and it is our hope that students and others interested will learn from it. The idea behind this compendium began in year 2008 at Risø DTU during the first PhD Summer School: Remote Sensing in Wind Energy. Thus......-of-the-art compendium available for people involved in Remote Sensing in Wind Energy....

  5. Remote Sensing and Imaging Physics

    Science.gov (United States)

    2012-03-07

    Program Manager AFOSR/RSE Air Force Research Laboratory Remote Sensing and Imaging Physics 7 March 2012 Report Documentation Page Form...00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Remote Sensing And Imaging Physics 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...Imaging of Space Objects •Information without Imaging •Predicting the Location of Space Objects • Remote Sensing in Extreme Conditions •Propagation

  6. Solitude and Growth in the Consciousness of Feminism---On Aoyama Nanae’s Good Weather ofOne Person%女性意识下的孤独与成长--论青山七惠的《一个人的好天气》

    Institute of Scientific and Technical Information of China (English)

    王先科

    2015-01-01

    The novel Good Weather ofOne Person written by Japanese authoress Aoyama Nanae ,in a relaxed tone,shows us the loneliness and growth of young women’s under the metropolis background.The felling of fe-male’s solitude and self - growth in the novel inflects her particular awareness to feminism,i.e.the self discovery and self cognition of the women.Although the feminism awareness in the novel is hidden in the simple narration a-bout the daily life,it always leads the development of the stories and becomes the focus to attract and move the readers.%日本作家青山七惠的小说《一个人的好天气》以轻松的笔调呈现出大都市背景下年轻女性的孤独与成长。小说中女性独特的孤独心理和自我成长体现了作者特有的女性意识,即作为女性对自我的发现和认知。这一女性意识隐藏在对日常生活的平淡叙述中,但始终牵引着故事的发展,成为小说吸引和感染读者的关键所在。

  7. Remote handling maintenance of ITER

    International Nuclear Information System (INIS)

    Haange, R.

    1999-01-01

    The remote maintenance strategy and the associated component design of the International Thermonuclear Experimental Reactor (ITER) have reached a high degree of completeness, especially with respect to those components that are expected to require frequent or occasional remote maintenance. Large-scale test stands, to demonstrate the principle feasibility of the remote maintenance procedures and to develop the required equipment and tools, were operational at the end of the Engineering Design Activities (EDA) phase. The initial results are highly encouraging: major remote equipment deployment and component replacement operations have been successfully demonstrated. (author)

  8. Factores relacionados con el descontrol de la presión arterial Factors associated with uncontrolled hypertension

    Directory of Open Access Journals (Sweden)

    Oliva Mejía-Rodríguez

    2009-08-01

    Full Text Available OBJETIVO: Evaluar las características de la atención del paciente hipertenso, y su relación con el descontrol de la presión arterial, en una unidad de medicina familiar. MATERIAL Y MÉTODOS: Diseño: estudio transversal. Se revisó la mitad de 8 080 (4 040 expedientes. Se registraron las características de los pacientes, los médicos tratantes y la unidad de atención. RESULTADOS: Se encontraron como factores asociados a la hipertensión descontrolada la edad (RM, 1.43; IC95%: 1.015-1.030, IMC (RM, 1.03; IC95%: 1.02-1.05, creatinina (RM, 1.16; IC95%: 1.03-1.30, tomar tres o más fármacos antihipertensivos (RM, 1.48; IC95%: 1.31-1.07, ser atendido por un médico con más de 20 años de antigüedad (RM, 1.21; IC95%: 1.06-1.39, sin especialidad (RM, 1.43; IC95%: 1.20-1.71 y ser atendido en el turno matutino (RM, 1.21; IC95%: 1.07-1.56. CONCLUSIONES: La presión arterial está bien controlada en la mayoría de los pacientes. En el descontrol de la presión arterial intervienen factores relacionados con el paciente mismo, pero las características del sistema de salud también tienen un papel significativo.OBJECTIVE: To assess health care characteristics for hypertensive patients and their association with uncontrolled hypertension in a primary care outpatient clinic. MATERIAL AND METHODS: Design: cross-sectional.A review was conducted of 50% of 8080 (n= 4040 files. Patient, physician and primary health care clinic characteristics were recorded. RESULTS: The factors associated with uncontrolled hypertension were: age (OR, 1.43; CI95% : 1.015-1.030, BMI (OR, 1.03; CI95%: 1.02-1.05, creatinine serum levels (OR, 1.16; CI95%: 1.03-1.30, three or more different antihypertensive drugs (OR, 1.48; CI95%: 1.31-1.07, to be treated by a physician with more than 20 years of medical practice (OR, 1.21; CI95%; 1.06-1.39 or by a non-specialist physician (OR, 1.43; CI95%: 1.20-1.71 and to be treated in the morningshift (OR, 1.21; CI95%: 1.07- 1.56. CONCLUSIONS

  9. Automatic remote communication system

    International Nuclear Information System (INIS)

    Yamamoto, Yoichi

    1990-05-01

    The Upgraded RECOVER (Remote Continual Verification) system is a communication system for remote continual verification of security and safeguards status of nuclear material in principal nuclear facilities. The system is composed of a command center and facility sub-systems. A command center is a mini-computer system to process C/S (Containment and Surveillance) status data. Facility sub-systems consists of OSM (On-site Multiplexer), MU (Monitoring Unit) and C/S sensor. The system uses public telephone network for communication between a command center and facility sub-systems, and it encrypts communication data to prevent falsification and wiretapping by unauthorized persons. This system inherits the design principle of RECOVER system that was tested by IAEA before. We upgraded and expanded its capabilities more than those of RECOVER. The development of this system began in 1983, and it finished in 1987. Performance tests of the system were carried out since 1987. It showed a farely good result with some indications which should need further improvements. The Upgraded RECOVER system provides timely information about the status of C/S systems, which could contribute to the reduction of inspection effort and the improvement of cost performance. (author)

  10. Wireless Remote Control System

    Directory of Open Access Journals (Sweden)

    Adrian Tigauan

    2012-06-01

    Full Text Available This paper presents the design of a wireless remote control system based on the ZigBee communication protocol. Gathering data from sensors or performing control tasks through wireless communication is advantageous in situations in which the use of cables is impractical. An Atmega328 microcontroller (from slave device is used for gathering data from the sensors and transmitting it to a coordinator device with the help of the XBee modules. The ZigBee standard is suitable for low-cost, low-data-rate and low-power wireless networks implementations. The XBee-PRO module, designed to meet ZigBee standards, requires minimal power for reliable data exchange between devices over a distance of up to 1600m outdoors. A key component of the ZigBee protocol is the ability to support networking and this can be used in a wireless remote control system. This system may be employed e.g. to control temperature and humidity (SHT11 sensor and light intensity (TSL230 sensor levels inside a commercial greenhouse.

  11. Geological remote sensing

    Science.gov (United States)

    Bishop, Charlotte; Rivard, Benoit; de Souza Filho, Carlos; van der Meer, Freek

    2018-02-01

    Geology is defined as the 'study of the planet Earth - the materials of which it is made, the processes that act on these materials, the products formed, and the history of the planet and its life forms since its origin' (Bates and Jackson, 1976). Remote sensing has seen a number of variable definitions such as those by Sabins and Lillesand and Kiefer in their respective textbooks (Sabins, 1996; Lillesand and Kiefer, 2000). Floyd Sabins (Sabins, 1996) defined it as 'the science of acquiring, processing and interpreting images that record the interaction between electromagnetic energy and matter' while Lillesand and Kiefer (Lillesand and Kiefer, 2000) defined it as 'the science and art of obtaining information about an object, area, or phenomenon through the analysis of data acquired by a device that is not in contact with the object, area, or phenomenon under investigation'. Thus Geological Remote Sensing can be considered the study of, not just Earth given the breadth of work undertaken in planetary science, geological features and surfaces and their interaction with the electromagnetic spectrum using technology that is not in direct contact with the features of interest.

  12. Remote control manipulator

    Energy Technology Data Exchange (ETDEWEB)

    Sugawara, T

    1970-02-28

    A prior-art remote control manipulator comprises a horizontal suspension section, a master arm and a slave arm which are coupled to ends of the suspension section in a manner to pivotally move relative to the suspension section, and a connecting device which includes a tape and which joins both the arms. When the connecting device malfunctions, the slave arm can neither be extended nor contracted. Means to keep the tension of the tape is required which restricts the extension length of the slave arm. Further, the slave arm can be moved only in the axial direction. The invention described provides an improved remote control manipulator of the specified type. A moving device which moves the slave arm relative to the master arm without the intervention of the connecting device is mounted on a movable part of the slave arm, while pulleys which maintain the joining relationship of the connecting device are mounted on the movable part and fixed part of the slave arm. Owing to this construction, movement of the slave arm is assured despite troubles which may arise in the connecting device. In addition, no slack arises in the tape. By applying a similar construction to the horizontal suspension section, the suspension section can be stretched, and hence, the slave arm can be moved in a direction orthogonal to its axis.

  13. A remote control valve

    International Nuclear Information System (INIS)

    Cachard, Maurice de; Dumont, Maurice.

    1976-01-01

    This invention concerns a remote control valve for shutting off or distributing a fluid flowing at a high rate and low pressure. Among the different valves at present in use, electric valves are the most recommended for remote control but their reliability is uncertain and they soon become costly when large diameter valves are used. The valve described in this invention does away with this drawback owing to its simplicity and the small number of moving parts, this makes it particularly reliable. It mainly includes: a tubular body fitted with at least one side opening; at least one valve wedge for this opening, coaxial with the body, and mobile; a mobile piston integral with this wedge. Several valves to the specifications of this invention can be fitted in series (a shut-off valve can be used in conjunction with one or more distribution valves). The fitting and maintenance of the valve is very simple owing to its design. It can be fabricated in any material such as metals, alloys, plastics and concrete. The structure of the valve prevents the flowing fluid from coming into contact with the outside environment, thereby making it particularly suitable in the handling of dangerous or corrosive fluids. Finally, the opening and shutting of the valve occurs slowly, thereby doing away with the water hammer effect so frequent in large bore pipes [fr

  14. Nitrate-rich beetroot juice selectively lowers ambulatory pressures and LDL cholesterol in uncontrolled but not controlled hypertension: a pilot study.

    Science.gov (United States)

    Kerley, C P; Dolan, E; Cormican, L

    2017-11-01

    Dietary nitrate has been shown to increase nitrate/nitrite levels in multiple populations, with potential blood pressure lowering effects. However, there are few reports among hypertensives. We aimed to assess the effect of daily nitrate in subjects with controlled hypertension vs. uncontrolled hypertension. On day 0, hypertensives wore an ambulatory BP monitor (ABPM) for 24 h and fasting blood was taken. Subjects then consumed concentrated beetroot juice (12.9 mmol nitrate) for 14 consecutive days. On day 14 subjects consumed their last nitrate dose after fasting blood was drawn and again had an ABPM for 24 h. According to baseline ABPM, 11 subjects had controlled BP while 8 had uncontrolled BP. There were similar, significant increases in serum nitrate/nitrite in both groups. We observed little change in BP variables among controlled hypertensives. However, there were reductions in BP variables in uncontrolled hypertensives where decreases in nighttime DBP (-6 ± 4.8 mmHg), arterial stiffness (-0.08 ± 0.03 ambulatory arterial stiffness index) and LDL (-0.36 ± 0.42 mmol/L) reached significance (p = 003, 0.05 and 0.046, respectively). Our results support the existing data suggesting an anti-hypertensive effect of nitrate-containing beetroot juice, but only among those with uncontrolled hypertension.

  15. PANTHER solution to the NEA-NSC 3-D PWR core transient benchmark. Uncontrolled withdrawal of control rods at zero power

    Energy Technology Data Exchange (ETDEWEB)

    Kuijper, J.C.

    1994-10-01

    This report contains the results of PANTHER calculations for the ``NEA-NSC 3-D PWR Core Transient Benchmark: Uncontrolled Withdrawal of Control Rods at Zero Power``. PANTHER was able to model the benchmark problems without modifications to the code. All the calculations were performed in 3-D. (orig.).

  16. Final PANTHER solution to the NEA-NSC3-DPWR core transient benchmark. Uncontrolled withdrawal of control rods at zero power

    International Nuclear Information System (INIS)

    Kuijper, J.C.

    1996-10-01

    This report contains the final results of PANTHER calculations for the 'NEA-NSC 3-D PWR Core Transient Benchmark: Uncontrolled Withdrawal of Control Rods at Zero Power'. PANTHER was able to model the benchmark problems without modifications to the code. All the calculations were performed in 3-D. (orig.)

  17. PANTHER solution to the NEA-NSC 3-D PWR core transient benchmark. Uncontrolled withdrawal of control rods at zero power

    International Nuclear Information System (INIS)

    Kuijper, J.C.

    1994-10-01

    This report contains the results of PANTHER calculations for the ''NEA-NSC 3-D PWR Core Transient Benchmark: Uncontrolled Withdrawal of Control Rods at Zero Power''. PANTHER was able to model the benchmark problems without modifications to the code. All the calculations were performed in 3-D. (orig.)

  18. Final PANTHER solution to the NEA-NSC3-DPWR core transient benchmark. Uncontrolled withdrawal of control rods at zero power

    Energy Technology Data Exchange (ETDEWEB)

    Kuijper, J.C.

    1996-10-01

    This report contains the final results of PANTHER calculations for the `NEA-NSC 3-D PWR Core Transient Benchmark: Uncontrolled Withdrawal of Control Rods at Zero Power`. PANTHER was able to model the benchmark problems without modifications to the code. All the calculations were performed in 3-D. (orig.).

  19. Continuous infusion of small-volume fluid resuscitation in the treatment of combined uncontrolled hemorrhagic shock and head injury

    International Nuclear Information System (INIS)

    Hayrettin, O.; Yagmur, Y.; Tas, A.; Topcu, S.; Orak, M.

    2007-01-01

    To determine the effect of continuous limited fluid resuscitation on the hemodynamic response and survival in rats in a model of uncontrolled hemorrhage shock due to Massive Splenic Injury (MSI) and Head Injury (HI). Seventy Sprague-Dawley rats were used in this study. Group 1 rats (n=10) was sham-operated. In group 2 (n=10), only Massive Splenic Injury (MSI) was performed and untreated. In group 3 (n=10), only head injury (HI) was performed and untreated. In group 4 (n=10), HI and MSI were performed and were untreated. In group 5 (n=10), HI and MSI were performed and 15 minutes later treated with 7.5% NaCl. In group 6 (n=10), HI and MSI were performed, and rats were treated with Ringer's Lactate (RL) solution. In group 7 (n=10), HI and MSI were performed, rats were treated with 0.9 % NaCl. In groups 2,4,5,6 and 7 midline incision was reopened and splenectomy was performed at 45 minutes. In group 4 rats, Mean Arterial Pressure (MAP) was decreased from 104 +- 6.1 mmHg to 75 +- 19.5 mmHg at 15 minutes; heart rate decreased from 357+- 24.9 beats/min to 321 +- 62.1 beats/min and hematocrit decreased from 46 +- 1.3 % to 43 +- 2.5 % (p<0.01). Similar early changes in MAP, heart rate and hematocrit were observed in groups 5, 6, and 7, at 15 minutes. At 45,60 and 120 minutes, in fluid resuscitated rats (group 5,6,7) MAP, heart rate and hematocrit values were measured higher than group 2 and 4 (p<0.01 for all). At 120 min. in group 6, hematocrit was higher than group 4, 5 and 7, in group 6, total blood loss after splenectomy was calculated at 20 +- 2.4% of blood volume and was the best value compared to other fluid resuscitated group 5 and 7 (28% and 27% of blood volume) (p<0.01). Mortality was lower in all fluid resuscitated groups when compared to group 3 and 4 (p< 0.05). The median survival time was again higher in fluid resuscitated groups. Continuous infusion of 7.5% NaCl, RL and 0.9 % NaCl following uncontrolled hemorrhagic shock with massive splenic injury and

  20. Uncontrolled re-entry of satellite parts after finishing their mission in LEO: Titanium alloy degradation by thermite reaction energy

    Science.gov (United States)

    Monogarov, K. A.; Pivkina, A. N.; Grishin, L. I.; Frolov, Yu. V.; Dilhan, D.

    2017-06-01

    Analytical and experimental studies conducted at Semenov Institute of Chemical Physics for investigating the use of pyrotechnic compositions, i.e., thermites, to reduce the risk of the fall of thermally stable parts of deorbiting end-of-life LEO satellites on the Earth are described. The main idea was the use of passive heating during uncontrolled re-entry to ignite thermite composition, fixed on the titanium surface, with the subsequent combustion energy release to be sufficient to perforate the titanium cover. It is supposed, that thus destructed satellite parts will lose their streamline shape, and will burn out being aerodynamically heated during further descending in atmosphere (patent FR2975080). On the base of thermodynamic calculations the most promising thermite compositions have been selected for the experimental phase. The unique test facilities have been developed for the testing of the efficiency of thermite charges to perforate the titanium TA6V cover of 0.8 mm thickness under temperature/pressure conditions duplicated the uncontrolled re-entry of titanium tank after its mission on LEO. Experiments with the programmed laser heating inside the vacuum chamber revealed the only efficient thermite composition among preliminary selected ones to be Al/Co3O4. Experimental searching of the optimal aluminum powder between spherical and flaked nano- and micron-sized ones revealed the possibility to adjust the necessary ignition delay time, according to the titanium cover temperature dependency on deorbiting time. For the titanium tank the maximum temperature is 1100 °C at altitude 68 km and pressure 60 Pa. Under these conditions Al/Co3O4 formulations with nano-Al spherical particles provide the ignition time to be 13.3 s, and ignition temperature as low as 592±5 °C, whereas compositions with the micron-sized spherical Al powder reveal these values to be much higher, i.e., 26.3 s and 869±5 °C, respectively. The analytical and experimental studies described

  1. The Role of Salivary Gland Scintigraphy in the Evaluation of Salivary Gland Dysfunction in Uncontrolled Type II Diabetic Patients.

    Science.gov (United States)

    Senthilkumar, B; Sathasivasubramanian, S

    2013-09-01

    The aim of the present study was to evaluate the salivary gland dysfunction in patients with uncontrolled type II diabetes using salivary gland scintigraphy and then to compare these ratios with quantitative whole salivary secretion rates. Using a gamma camera (siemens-diacam) equipped with a low energy all-purpose collimator, 32 uncontrolled type II diabetic patients and 30 normal healthy patients were studied by injecting a radio isotope (technetium 99m pertechnetate) about 5 mCi was injected intravenously in to anticubital vein and the activity was measured for the 1(st), 20(th) and 40(th) min. At 20 min after injection, vitamin C chewable tablet was given to stimulate the secretion and continued until the end of the study period (40 min). Before scintigraphy, salivary sampling was carried out in both diabetic and normal individuals in a quiet room, saliva was allowed to accumulate and was expectorated into the collecting vessel approximately once a minute for 15 min and the volume was recorded as Unstimulated salivary flow rate and after 5 min break vitamin C chewable tablet was given to stimulate the secretion and the patient was asked to expectorate the saliva in the collecting vessel for 5 min. The expectorated volume was recorded as stimulated salivary flow rate. The mean of the measurements of scintigraphic ratio and salivary secretion rates were compared using the paired Student's t-test. The scintigraphic mean uptake and excretory ratio (ER) and the salivary flow rates were correlated. The result shows that there was a significant correlation between salivary flow rate and scintigraphic uptake and ER. However, statistically significant result could not be derived as it may be due to smaller sample size and marginal difference in the scintigraphic values between the groups. Salivary gland scintigraphy plays a significant role in the evaluation of salivary gland dysfunction. However, its role as an independent investigative procedure in the evaluation of

  2. The Role of Salivary Gland Scintigraphy in the Evaluation of Salivary Gland Dysfunction in Uncontrolled Type II Diabetic Patients

    International Nuclear Information System (INIS)

    Senthilkumar, B.; Sathasivasubramanian, S.

    2013-01-01

    The aim of the present study was to evaluate the salivary gland dysfunction in patients with uncontrolled type II diabetes using salivary gland scintigraphy and then to compare these ratios with quantitative whole salivary secretion rates. Using a gamma camera (siemens-diacam) equipped with a low energy all-purpose collimator, 32 uncontrolled type II diabetic patients and 30 normal healthy patients were studied by injecting a radio isotope (technetium 99m pertechnetate) about 5 mCi was injected intravenously in to anticubital vein and the activity was measured for the 1 st , 20 th and 40 th min. At 20 min after injection, vitamin C chewable tablet was given to stimulate the secretion and continued until the end of the study period (40 min). Before scintigraphy, salivary sampling was carried out in both diabetic and normal individuals in a quiet room, saliva was allowed to accumulate and was expectorated into the collecting vessel approximately once a minute for 15 min and the volume was recorded as Unstimulated salivary flow rate and after 5 min break vitamin C chewable tablet was given to stimulate the secretion and the patient was asked to expectorate the saliva in the collecting vessel for 5 min. The expectorated volume was recorded as stimulated salivary flow rate. The mean of the measurements of scintigraphic ratio and salivary secretion rates were compared using the paired Student's t-test. The scintigraphic mean uptake and excretory ratio (ER) and the salivary flow rates were correlated. The result shows that there was a significant correlation between salivary flow rate and scintigraphic uptake and ER. However, statistically significant result could not be derived as it may be due to smaller sample size and marginal difference in the scintigraphic values between the groups. Salivary gland scintigraphy plays a significant role in the evaluation of salivary gland dysfunction. However, its role as an independent investigative procedure in the evaluation

  3. Effects of packaging and heat transfer kinetics on drug-product stability during storage under uncontrolled temperature conditions.

    Science.gov (United States)

    Nakamura, Toru; Yamaji, Takayuki; Takayama, Kozo

    2013-05-01

    To predict the stability of pharmaceutical preparations under uncontrolled temperature conditions accurately, a method to compute the average reaction rate constant taking into account the heat transfer from the atmosphere to the product was developed. The average reaction rate constants computed with taken into consideration heat transfer (κ(re) ) were then compared with those computed without taking heat transfer into consideration (κ(in) ). The apparent thermal diffusivity (κ(a) ) exerted some influence on the average reaction rate constant ratio (R, R = κ(re) /κ(in) ). In the regions where the κ(a) was large (above 1 h(-1) ) or very small, the value of R was close to 1. On the contrary, in the middle region (0.001-1 h(-1) ), the value of R was less than 1.The κ(a) of the central part of a large-size container and that of the central part of a paper case of 10 bottles of liquid medicine (100 mL) fell within this middle region. On the basis of the above-mentioned considerations, heat transfer may need to be taken into consideration to enable a more accurate prediction of the stability of actual pharmaceutical preparations under nonisothermal atmospheres. Copyright © 2013 Wiley Periodicals, Inc.

  4. [Metabolic parameters in patients with steatosis non alcoholic liver and controlled diabetes type 2 versus uncontrolled diabetes type 2].

    Science.gov (United States)

    Miranda Manrique, Gonzalo

    2016-01-01

    Non-alcoholic fatty liver (NASH) is widely distributed around the world and is more common in subjects with dyslipidemia, metabolic syndrome obese and DM2 (34-74%). However, the prevalence of cirrhosis by NASH in general population is unknown which is still subject of research. To determine if there are significant differences between metabolic parameters of non-alcoholic fatty liver in controlled versus uncontrolled diabetes type 2 of recent diagnosis. retrospective case-control study, performed in the Hospital Guillermo Almenara Irigoyen, Lima, Peru from November 2014 to February 2015.This study included 231 patients: 147 patients (NASH with DM2 of recent diagnosis and poor control) and 84 patients (NASH with DM2 ofrecent diagnosis and adequate control). Levene test for evaluating homogeneity of variances intra groups and parametric test for independent samples. After applying Levene test of homogeneity and student test, significant metabolic parameters were the triglycerides, HbA1C level, metformin dose and gender. It is important in diabetic patients to diagnose NASH early for a tighter control, not only of glucose but other metabolic parameters mainly triglycerides which strongly supports existing concept of "multiple hits" which considers NASH affects glucose homeostasis, and it could be the starting point of new research to improve interventions for decreasing progression from to cirrhosis in diabetic patients and also to delay progression of diabetes mellitus in patients with non alcoholic steatohepatitis.

  5. [Prospective, monocentric, uncontrolled study of efficacy, tolerance and adherence of cyclosporin 0.1 % for severe dry eye syndrome].

    Science.gov (United States)

    Boujnah, Y; Mouchel, R; El-Chehab, H; Dot, C; Burillon, C; Kocaba, V

    2018-02-01

    To evaluate the efficacy, tolerability and treatment adherence of Ikervis ® (Santen, SAS) (ciclosporine 0.1 %) for first line therapy or following treatment with Restasis ® (Allergan, Inc.) (ciclosporine 0.05 %) for severe dry eye syndrome. A prospective, monocentric, uncontrolled study was conducted between January 2012 and March 2015 on 110 eyes of 55 patients with severe dry eye on first line therapy or previously treated with Restasis ® who required the introduction of Ikervis ® . Patients' quality of life was assessed before and after treatment was started using a standardized questionnaire (Ocular Surface Disease Index © [OSDI]), clinical efficacy was quantified at the slit lamp, by measurement of the Break Up time Test (BUT) and the Oxford classification. Tolerability and adherence to treatment were measured using a simple questionnaire. A total of 72 eyes of 37 patients were included. Etiologies of dry eye syndrome were dominated by Sjögren syndrome (32 %) and severe ocular surface conditions (48 %). The mean age was 57.7 years (±17.45) and mean follow-up was 458 days (±292). The mean BUT increased by 2.043seconds [1.522-2.563] (Pdry eye. Its indications tend to evolve towards less severe dry eye. However, the tolerability profile remains poor, and an improvement in this would be desirable. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  6. Studies of Limits on Uncontrolled Heavy Ion Beam Losses for Allowing Hands-On Maintenance. Final report

    International Nuclear Information System (INIS)

    Ronningen, Reginald M.; Remec, Igor

    2010-01-01

    Dose rates from accelerator components activated by 1 W/m beam losses are obtained semiempirically for a 1 GeV proton beam and by use of Monte Carlo transport codes for the proton beam and for 777 MeV/u 3He, 500 MeV/u 48Ca, 86Kr, 136Xe, and 400 MeV/u 238U ions. The dose rate obtained by the semi-empirical method, 0.99 mSv/h (99 mrem/h) at 30 cm, 4 h after 100 d irradiation by a 1-GeV proton beam, is consistent with studies at several accelerator facilities and with adopted hands-on maintenance dose rate limits. Monte Carlo simulations verify this result for protons and extend studies to heavy ion beam losses in drift-tube linac and superconducting linac accelerating structures. The studies indicate that the 1 W/m limit imposed on uncontrolled beam losses for high-energy proton beams might be relaxed for heavy ion beams. These studies further suggest that using the ratio of neutrons produced by a heavy ion beam to neutrons produced by a proton beam along with the dose rate from the proton beam (for thin-target scenarios) should allow an estimate of the dose rates expected from heavy ion beam losses.

  7. Comparison of Costs and Clinical Outcomes Between Hospital and Outpatient Administration of Omalizumab in Patients With Severe Uncontrolled Asthma.

    Science.gov (United States)

    Chiner, Eusebi; Fernández-Fabrellas, Estrella; Landete, Pedro; Novella, Laura; Ramón, Mercedes; Sancho-Chust, José Norberto; Senent, Cristina; Berraondo, Javier

    2016-04-01

    To compare clinical outcomes and costs between two administration strategies of omalizumab treatment. We evaluated two cohorts of patients with uncontrolled severe asthma over a 1-year period. Patients received the treatment in the primary care center in Hospital A and conventional hospital administration in Hospital B. We studied 130 patients, 86 in Hospital A and 44 in Hospital B, 30 men (24%) and 100 women (76%), age 50 ± 15 years, FEV1% 67 ± 22%, body mass index (BMI) 28 ± 6 kg/m(2), 639 ± 747 UI IgE/mL, followed for 24 ± 11 months (12-45), Asthma Control Test (ACT) score 12 ± 4 and Asthma Control Questionnaire (ACQ) 3 ± 2. There were no significant pretreatment differences between the groups in hospital admissions and emergency room visits in the previous year, nor in proportion of patients receiving oral steroids. Evaluations were performed at baseline and after 12 months of treatment, revealing significant differences in ACT (Ptravel costs were 35% lower in the ambulatory strategy adopted in Hospital A. The administration of omalizumab in ambulatory health centers achieved the same clinical results as a hospital administration strategy, but with lower costs. Copyright © 2015 SEPAR. Published by Elsevier Espana. All rights reserved.

  8. Simultaneous Implantation of an Ahmed and Baerveldt Glaucoma Drainage Device for Uncontrolled Intraocular Pressure in Advanced Glaucoma.

    Science.gov (United States)

    Rao, Veena S; Christenbury, Joseph; Lee, Paul; Allingham, Rand; Herndon, Leon; Challa, Pratap

    2017-02-01

    To evaluate efficacy and safety of a novel technique, simultaneous implantation of Ahmed and Baerveldt shunts, for improved control of intraocular pressure (IOP) in advanced glaucoma with visual field defects threatening central fixation. Retrospective case series; all patients receiving simultaneous Ahmed and Baerveldt implantation at a single institution between October 2004 and October 2009 were included. Records were reviewed preoperatively and at postoperative day 1, week 1, month 1, month 3, month 6, year 1, and yearly until year 5. Outcome measures included IOP, best-corrected visual acuity, visual field mean deviation, cup to disc ratio, number of glaucoma medications, and complications. Fifty-nine eyes were identified; mean (±SD) follow-up was 26±23 months. Primary open-angle glaucoma was most common (n=37, 63%). Forty-six eyes (78%) had prior incisional surgery. Mean preoperative IOP was 25.5±9.8 mm Hg. IOP was reduced 50% day 1 (Pglaucoma tube implantation with effects persisting over postoperative year 1 and up to year 5. Complications were higher than that seen in reports of single shunt implantation, which may be explained by patient complexity in this cohort. This technique may prove a promising novel approach for management of uncontrolled IOP in advanced glaucoma.

  9. Microbiome Responses to an Uncontrolled Short-Term Diet Intervention in the Frame of the Citizen Science Project.

    Science.gov (United States)

    Klimenko, Natalia S; Tyakht, Alexander V; Popenko, Anna S; Vasiliev, Anatoly S; Altukhov, Ilya A; Ischenko, Dmitry S; Shashkova, Tatiana I; Efimova, Daria A; Nikogosov, Dmitri A; Osipenko, Dmitrii A; Musienko, Sergey V; Selezneva, Kseniya S; Baranova, Ancha; Kurilshikov, Alexander M; Toshchakov, Stepan M; Korzhenkov, Aleksei A; Samarov, Nazar I; Shevchenko, Margarita A; Tepliuk, Alina V; Alexeev, Dmitry G

    2018-05-08

    Personalized nutrition is of increasing interest to individuals actively monitoring their health. The relations between the duration of diet intervention and the effects on gut microbiota have yet to be elucidated. Here we examined the associations of short-term dietary changes, long-term dietary habits and lifestyle with gut microbiota. Stool samples from 248 citizen-science volunteers were collected before and after a self-reported 2-week personalized diet intervention, then analyzed using 16S rRNA sequencing. Considerable correlations between long-term dietary habits and gut community structure were detected. A higher intake of vegetables and fruits was associated with increased levels of butyrate-producing Clostridiales and higher community richness. A paired comparison of the metagenomes before and after the 2-week intervention showed that even a brief, uncontrolled intervention produced profound changes in community structure: resulting in decreased levels of Bacteroidaceae , Porphyromonadaceae and Rikenellaceae families and decreased alpha-diversity coupled with an increase of Methanobrevibacter , Bifidobacterium , Clostridium and butyrate-producing Lachnospiraceae - as well as the prevalence of a permatype (a bootstrapping-based variation of enterotype) associated with a higher diversity of diet. The response of microbiota to the intervention was dependent on the initial microbiota state. These findings pave the way for the development of an individualized diet.

  10. Microbiome Responses to an Uncontrolled Short-Term Diet Intervention in the Frame of the Citizen Science Project

    Directory of Open Access Journals (Sweden)

    Natalia S. Klimenko

    2018-05-01

    Full Text Available Personalized nutrition is of increasing interest to individuals actively monitoring their health. The relations between the duration of diet intervention and the effects on gut microbiota have yet to be elucidated. Here we examined the associations of short-term dietary changes, long-term dietary habits and lifestyle with gut microbiota. Stool samples from 248 citizen-science volunteers were collected before and after a self-reported 2-week personalized diet intervention, then analyzed using 16S rRNA sequencing. Considerable correlations between long-term dietary habits and gut community structure were detected. A higher intake of vegetables and fruits was associated with increased levels of butyrate-producing Clostridiales and higher community richness. A paired comparison of the metagenomes before and after the 2-week intervention showed that even a brief, uncontrolled intervention produced profound changes in community structure: resulting in decreased levels of Bacteroidaceae, Porphyromonadaceae and Rikenellaceae families and decreased alpha-diversity coupled with an increase of Methanobrevibacter, Bifidobacterium, Clostridium and butyrate-producing Lachnospiraceae- as well as the prevalence of a permatype (a bootstrapping-based variation of enterotype associated with a higher diversity of diet. The response of microbiota to the intervention was dependent on the initial microbiota state. These findings pave the way for the development of an individualized diet.

  11. Analysis of NEA-NSC PWR Uncontrolled Control Rod Withdrawal at Zero Power Benchmark Cases with NODAL3 Code

    Directory of Open Access Journals (Sweden)

    Tagor Malem Sembiring

    2017-01-01

    Full Text Available The in-house coupled neutronic and thermal-hydraulic (N/T-H code of BATAN (National Nuclear Energy Agency of Indonesia, NODAL3, based on the few-group neutron diffusion equation in 3-dimensional geometry using the polynomial nodal method, has been verified with static and transient PWR benchmark cases. This paper reports the verification of NODAL3 code in the NEA-NSC PWR uncontrolled control rods withdrawal at zero power benchmark. The objective of this paper is to determine the accuracy of NODAL3 code in solving the continuously slow and fast reactivity insertions due to single and group of control rod bank withdrawn while the power and temperature increment are limited by the Doppler coefficient. The benchmark is chosen since many organizations participated using various methods and approximations, so the calculation results of NODAL3 can be compared to other codes’ results. The calculated parameters are performed for the steady-state, transient core averaged, and transient hot pellet results. The influence of radial and axial nodes number was investigated for all cases. The results of NODAL3 code are in very good agreement with the reference solutions if the radial and axial nodes number is 2 × 2 and 2 × 18 (total axial layers, respectively.

  12. Participation in mindfulness-based stress reduction is not associated with reductions in emotional eating or uncontrolled eating.

    Science.gov (United States)

    Kearney, David J; Milton, Meredith L; Malte, Carol A; McDermott, Kelly A; Martinez, Michelle; Simpson, Tracy L

    2012-06-01

    The adverse health effects and increasing prevalence of obesity in the United States make interventions for obesity a priority in health research. Diet-focused interventions generally do not result in lasting reductions in weight. Behavioral interventions that increase awareness of eating cues and satiety have been postulated to result in healthier eating habits. We hypothesized that participation in a program called mindfulness-based stress reduction (MBSR) would positively influence the eating behaviors and nutritional intake of participants through changes in emotional eating (EE), uncontrolled eating (UE), and type and quantity of food consumed. Forty-eight veterans at a large urban Veterans Administration medical center were assessed before MBSR, after MBSR, and 4 months later. For all participants (N = 48), MBSR participation was not associated with significant changes in EE or UE. In addition, there were no significant differences in the intake of energy, fat, sugar, fruit, or vegetables at either follow-up time point as compared with baseline. Enhanced mindfulness skills and reduced depressive symptoms were seen over time with medium to large effect sizes. Changes in mindfulness skills were significantly and negatively correlated with changes in EE and UE over time. Overall, there was no evidence that participation in MBSR was associated with beneficial changes in eating through reductions in disinhibited eating or significant changes in dietary intake. Randomized studies are needed to further define the relationship between mindfulness program participation and eating behaviors. Published by Elsevier Inc.

  13. Quality of cowpea seeds treated with chemicals and stored in controlled and uncontrolled temperature and humidity conditions

    Directory of Open Access Journals (Sweden)

    Lucicléia Mendes de Oliveira

    2015-06-01

    Full Text Available The cowpea is a Fabaceae originated in Africa cultivated in the northern and northeastern of Brazil, where stands out as the main source of protein for the population. For the establishment of culture, seeds are treated to control and prevent pest attacks and diseases, can also attach nutrients to the seeds which will be available for plant development. The objective of the research was to evaluate the performance of cowpea seeds treated with chemical products and stored in controlled and uncontrolled temperature and humidity conditions. The following seeds treatments were applied: control (no treatment; micronutrient Comol 118, insecticide thiamethoxam, fipronil and pyraclostrobin+thiophanate-methyl and imidacloprid+thiodicarb were then stored in a cold environment and natural. The assessment of physiological seed quality was made initially and every 45 days through the germination and vigor. Among all products used, the imidacloprid + thiodicarb and fipronil + pyraclostrobin + thiophanate methyl provides stimulating effect on seed performance; seeds treated with thiamethoxam were less affected by storage than the untreated seeds; seeds treated with micronutrients exhibits similar behavior to untreated seeds and storage in a controlled environment better preserves the seed physiological quality.

  14. Remote Testing of Timed Specifications

    DEFF Research Database (Denmark)

    David, Alexandre; Larsen, Kim Guldstrand; Mikucionis, Marius

    2013-01-01

    We present a study and a testing framework on black box remote testing of real-time systems using UPPAAL TIGA. One of the essential challenges of remote testing is the communication latency between the Tester and the System Under Test (IUT) that may lead to interleaving of inputs and outputs. Thi...

  15. Detecting Motor Impairment in Early Parkinson’s Disease via Natural Typing Interaction With Keyboards: Validation of the neuroQWERTY Approach in an Uncontrolled At-Home Setting

    Science.gov (United States)

    Ledesma-Carbayo, María J; Butterworth, Ian; Matarazzo, Michele; Montero-Escribano, Paloma; Puertas-Martín, Verónica; Gray, Martha L

    2018-01-01

    Background Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease and one of the most common forms of movement disorder. Although there is no known cure for PD, existing therapies can provide effective symptomatic relief. However, optimal titration is crucial to avoid adverse effects. Today, decision making for PD management is challenging because it relies on subjective clinical evaluations that require a visit to the clinic. This challenge has motivated recent research initiatives to develop tools that can be used by nonspecialists to assess psychomotor impairment. Among these emerging solutions, we recently reported the neuroQWERTY index, a new digital marker able to detect motor impairment in an early PD cohort through the analysis of the key press and release timing data collected during a controlled in-clinic typing task. Objective The aim of this study was to extend the in-clinic implementation to an at-home implementation by validating the applicability of the neuroQWERTY approach in an uncontrolled at-home setting, using the typing data from subjects’ natural interaction with their laptop to enable remote and unobtrusive assessment of PD signs. Methods We implemented the data-collection platform and software to enable access and storage of the typing data generated by users while using their computer at home. We recruited a total of 60 participants; of these participants 52 (25 people with Parkinson’s and 27 healthy controls) provided enough data to complete the analysis. Finally, to evaluate whether our in-clinic-built algorithm could be used in an uncontrolled at-home setting, we compared its performance on the data collected during the controlled typing task in the clinic and the results of our method using the data passively collected at home. Results Despite the randomness and sparsity introduced by the uncontrolled setting, our algorithm performed nearly as well in the at-home data (area under the receiver operating

  16. Remote handling machines

    International Nuclear Information System (INIS)

    Sato, Shinri

    1985-01-01

    In nuclear power facilities, the management of radioactive wastes is made with its technology plus the automatic techniques. Under the radiation field, the maintenance or aid of such systems is important. To cope with this situation, MF-2 system, MF-3 system and a manipulator system as remote handling machines are described. MF-2 system consists of an MF-2 carrier truck, a control unit and a command trailer. It is capable of handling heavy-weight objects. The system is not by hydraulic but by electrical means. MF-3 system consists of a four-crawler truck and a manipulator. The truck is versatile in its posture by means of the four independent crawlers. The manipulator system is bilateral in operation, so that the delicate handling is made possible. (Mori, K.)

  17. Remote controlled transport device

    International Nuclear Information System (INIS)

    Nakahira, Masataka; Oka, Kiyoshi; Ito, Akira; Tada, Eisuke; Sato, Masaki

    1998-01-01

    The present invention provides a device for transporting equipments for maintenance and parts between a maintenance port and a facility for maintenance by remote control in a radioactive material handling facility such as a nuclear power plant. Namely, a power supply bus bar is disposed along a transferring path in order to supply power to a transporting means, and is divided into every region having a predetermined length. Each of the power supply bus bar regions is controlled for the power supply by a control device. Accordingly, the transporting means can be moved and driven successively being independent on every power supply bus bar region. Accordingly, a plurality of transporting means can be operated independently in a transferring path without laying around power cables and control signal cables. (I.S.)

  18. Demographics and remote locations

    Energy Technology Data Exchange (ETDEWEB)

    Coppus, G. [Dynawise Inc., Calgary, AB (Canada)

    2005-07-01

    Within the next decade, the number of people leaving the workforce will exceed the number of new entrants. The demand for workers is expected to increase in Alberta due to oil sands industry growth. Sixty-four per cent of all responding federal, provincial, and municipal government organizations have reported shortages in their work environments, and almost 8 in 10 organizations predict they will continue to be understaffed in the next 3 to 5 years. Tightness in the general labour market will have an impact on employers in remote locations, and planning is essential to avoid the creation of a mercenary culture and a reliance on compensation. Challenges found in remote locations include high turnover rates among recent hires; critical gaps in service length; aggressive retirement; and the fact that the local population is often seen as unqualified for many industrial jobs. This Power Point presentation suggested that although decisions to join or quit a company are often based on considerations such as the organizational environment and amount of compensation, the relationship between employees and management is the most important attribute in many career decisions. Rigorous quantitative analysis of current demographics combined with forecasting analysis may help to forestall recruitment difficulties for many companies. Productivity analyses, and the effects of work overload on absenteeism, attrition and quality of workmanship must also be examined. Many companies are now focusing on retention and development strategies on mid-career staff to address depletion, as well as redesigning procedures to operate with less skilled staff. It was concluded that extra efforts are now being made to attract non-traditional employees, and non-traditional employment models are being considered by some companies. refs., tabs., figs.

  19. Mississippi Sound Remote Sensing Study

    Science.gov (United States)

    Atwell, B. H.

    1973-01-01

    The Mississippi Sound Remote Sensing Study was initiated as part of the research program of the NASA Earth Resources Laboratory. The objective of this study is development of remote sensing techniques to study near-shore marine waters. Included within this general objective are the following: (1) evaluate existing techniques and instruments used for remote measurement of parameters of interest within these waters; (2) develop methods for interpretation of state-of-the-art remote sensing data which are most meaningful to an understanding of processes taking place within near-shore waters; (3) define hardware development requirements and/or system specifications; (4) develop a system combining data from remote and surface measurements which will most efficiently assess conditions in near-shore waters; (5) conduct projects in coordination with appropriate operating agencies to demonstrate applicability of this research to environmental and economic problems.

  20. Pellet presses for remote fuel fabrication

    International Nuclear Information System (INIS)

    Densley, P.J.

    1978-01-01

    Two types of mechanical presses are being tested from the remote operation and remote maintenance aspects. Results will be used to recommend the type of press and design considerations required for operation in a remotely operated and maintained process line

  1. Impact of 5-HT(3) RA selection within triple antiemetic regimens on uncontrolled highly emetogenic chemotherapy-induced nausea/vomiting.

    Science.gov (United States)

    Schwartzberg, Lee; Jackson, James; Jain, Gagan; Balu, Sanjeev; Buchner, Deborah

    2011-08-01

    It is recommended that patients initiate triple antiemetic therapy with one of the 5-hydroxytryptamine receptor antagonists (5-HT(3) RAs), aprepitant (or its intravenous prodrug fosaprepitant) and dexamethasone prior to the start of highly emetogenic chemotherapy (HEC). However, the impact of 5-HT(3) RA selection within triple antiemetic regimens on the risk of uncontrolled chemotherapy-induced nausea and vomiting (CINV) with HEC has not been well studied. To assess the likelihood of an uncontrolled CINV event following antiemetic prophylaxis with the 5-HT(3) RA palonosetron + aprepitant/fosaprepitant + dexamethasone (palonosetron cohort) versus any of the other 5-HT(3) RAs + aprepitant/fosaprepitant + dexamethasone (other 5-HT(3) RA cohort) among single-day HEC cycles. Single-day HEC cycles (a gap of at least 5 days between two administrations) among patients with a cancer diagnosis and receiving antiemetic prophylaxis with the aforementioned regimens between 1/1/2006 and 6/30/2010 were identified from the IMS LifeLink claims database. Uncontrolled CINV events were identified through ICD-9-CM codes (nausea and vomiting), Current Procedural Terminology codes (hydration), rescue medications and/or use of antiemetic therapy from days 2-5 following HEC administration. Risks for an uncontrolled CINV event among all patients, and within breast cancer and multiple cancer subpopulations, were analyzed at cycle level using logistic multivariate regression models. A total of 8018 cycles for the palonosetron cohort and 1926 cycles for the other 5-HT(3) RA cohort (3574 and 978 patients, respectively) were analyzed. Single-day HEC cycles received by the palonosetron cohort had a significantly lower unadjusted risk of an uncontrolled CINV event (17.5 vs 20.7% for the other 5-HT(3) RA cohort; p = 0.0010), with a 17% lower adjusted risk for palonosetron-administered cycles (odds ratio: 0.83; 95% CI: 0.73-0.94; p = 0.0042). Results in the breast cancer and multiple cancer

  2. Remote participation for LHD experiments

    International Nuclear Information System (INIS)

    Emoto, M.; Yamamoto, T.; Komada, S.; Nagayama, Y.

    2006-01-01

    To accomplish a large-scale experiment, such as large helical device (LHD) experiment, effective cooperation among institutes is necessary. In order to establish such cooperation, the NIFS provides the following remote participation facilities for the LHD experiments. (1) Remote access: The user can use a virtual private network (VPN) to connect to the LAN. This is the most flexible technique to participate in the experiments. The users who are not familiar with the experiments can log into the remote server running MetaFrame and Linux. In these computers, the required software is already installed. Therefore, the user need not be concerned with installing software. (2) Remote data reference: A mirror server exists to provide physical data to remote users. Moreover, the users can retrieve summarized data via a web server, which provides summarized information of each discharge experiment and graphs of the principal physical data. These graphs are useful for finding the required data quickly. (3) Remote communication and monitoring: For effective remote cooperation, communication between researchers is very important. For this purpose, a video conferencing system and a video streaming service are available. In addition to these facilities, the NIFS introduced Super SINET in 2002. This is an optical-fiber-based network. The backbone speed of this network is 10 Gbps, and the speed is 1 Gbps for direct connections

  3. The ITER remote maintenance system

    International Nuclear Information System (INIS)

    Tesini, A.; Palmer, J.

    2007-01-01

    ITER is a joint international research and development project that aims to demonstrate the scientific and technological feasibility of fusion power. As soon as the plasma operation begins using tritium, the replacement of the vacuum vessel internal components will need to be done with remote handling techniques. To accomplish these operations ITER has equipped itself with a Remote Maintenance System; this includes the Remote Handling equipment set and the Hot Cell facility. Both need to work in a cooperative way, with the aim of minimizing the machine shutdown periods and to maximize the machine availability. The ITER Remote Handling equipment set is required to be available, robust, reliable and retrievable. The machine components, to be remotely handle-able, are required to be designed simply so as to ease their maintenance. The baseline ITER Remote Handling equipment is described. The ITER Hot Cell Facility is required to provide a controlled and shielded area for the execution of repair operations (carried out using dedicated remote handling equipment) on those activated components which need to be returned to service, inside the vacuum vessel. The Hot Cell provides also the equipment and space for the processing and temporary storage of the operational and decommissioning radwaste. A conceptual ITER Hot Cell Facility is described. (orig.)

  4. Remote participation for LHD experiments

    Energy Technology Data Exchange (ETDEWEB)

    Emoto, M. [National Institute for Fusion Science, National Institutes of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan)]. E-mail: emoto.masahiko@LHD.nifs.ac.jp; Yamamoto, T. [National Institute for Fusion Science, National Institutes of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Komada, S. [National Institute for Fusion Science, National Institutes of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan); Nagayama, Y. [National Institute for Fusion Science, National Institutes of Natural Sciences, 322-6 Oroshi, Toki 509-5292 (Japan)

    2006-07-15

    To accomplish a large-scale experiment, such as large helical device (LHD) experiment, effective cooperation among institutes is necessary. In order to establish such cooperation, the NIFS provides the following remote participation facilities for the LHD experiments. (1) Remote access: The user can use a virtual private network (VPN) to connect to the LAN. This is the most flexible technique to participate in the experiments. The users who are not familiar with the experiments can log into the remote server running MetaFrame and Linux. In these computers, the required software is already installed. Therefore, the user need not be concerned with installing software. (2) Remote data reference: A mirror server exists to provide physical data to remote users. Moreover, the users can retrieve summarized data via a web server, which provides summarized information of each discharge experiment and graphs of the principal physical data. These graphs are useful for finding the required data quickly. (3) Remote communication and monitoring: For effective remote cooperation, communication between researchers is very important. For this purpose, a video conferencing system and a video streaming service are available. In addition to these facilities, the NIFS introduced Super SINET in 2002. This is an optical-fiber-based network. The backbone speed of this network is 10 Gbps, and the speed is 1 Gbps for direct connections.

  5. Six-minute walk test and respiratory muscle strength in patients with uncontrolled severe asthma: a pilot study.

    Science.gov (United States)

    Pereira, Luiz Fernando Ferreira; Mancuzo, Eliane Viana; Rezende, Camila Farnese; Côrrea, Ricardo de Amorim

    2015-01-01

    To evaluate respiratory muscle strength and six-minute walk test (6MWT) variables in patients with uncontrolled severe asthma (UCSA). This was a cross-sectional study involving UCSA patients followed at a university hospital. The patients underwent 6MWT, spirometry, and measurements of respiratory muscle strength, as well as completing the Asthma Control Test (ACT). The Mann-Whitney test was used in order to analyze 6MWT variables, whereas the Kruskal-Wallis test was used to determine whether there was an association between the use of oral corticosteroids and respiratory muscle strength. We included 25 patients. Mean FEV1 was 58.8 ± 21.8% of predicted, and mean ACT score was 14.0 ± 3.9 points. No significant difference was found between the median six-minute walk distance recorded for the UCSA patients and that predicted for healthy Brazilians (512 m and 534 m, respectively; p = 0.14). During the 6MWT, there was no significant drop in SpO2. Mean MIP and MEP were normal (72.9 ± 15.2% and 67.6 ± 22.2%, respectively). Comparing the patients treated with at least four courses of oral corticosteroids per year and those treated with three or fewer, we found no significant differences in MIP (p = 0.15) or MEP (p = 0.45). Our findings suggest that UCSA patients are similar to normal subjects in terms of 6MWT variables and respiratory muscle strength. The use of oral corticosteroids has no apparent impact on respiratory muscle strength.

  6. White coat effect and masked uncontrolled hypertension in treated hypertensive-diabetic patients: Prevalence and target organ damage.

    Science.gov (United States)

    Leiria, Liana F; Severo, Mateus D; Ledur, Priscila S; Becker, Alexandre D; Aguiar, Fernanda M; Massierer, Daniela; Freitas, Valéria C; Schaan, Beatriz D; Gus, Miguel

    2015-09-01

    The association between hypertensive phenotypes of controlled hypertension (CH), white-coat effect (WCE), masked uncontrolled hypertension (MUH) and sustained hypertension (SH) with target organ damage have not been clearly established in diabetic hypertensive treated patients. The present study aims to evaluate the prevalence of the four phenotypes considering the current cut-off points for office and 24 h-ambulatory blood pressure monitoring (ABPM) and the association with left ventricle hypertrophy (LVH), diastolic function and nephropathy. Cross-sectional study with 304 patients on anti-hypertensive treatment aged 57.6 ± 6.1 years, who were submitted to ABPM and echocardiography. They were classified into CH (normal office BP and ABPM), WCE (high office BP and normal ABPM), MUH (normal office BP and high ABPM), and SH (high office BP and ABPM). Median HbA1c and diabetes duration were 7.9% (6.8-9.2), and 10 years (5-16), respectively. Prevalences of CH, WCE, MUH and SH were 27.3%, 17.1%, 18.8%, and 36.8%. MUH prevalence was higher than previously described. There was a significant increasing trend across the four groups in variables related to LVH (P ABPM beyond the traditional cardiovascular risk stratification tools has limitations, but is still useful in high-risk patients. Longitudinal studies could better evaluate the role of the use of ABPM in this scenario. Cut-off points for normality of office and ABPM influence the prevalences of WCH and MUH. © 2014 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.

  7. The cost of believing emotions are uncontrollable: Youths' beliefs about emotion predict emotion regulation and depressive symptoms.

    Science.gov (United States)

    Ford, Brett Q; Lwi, Sandy J; Gentzler, Amy L; Hankin, Benjamin; Mauss, Iris B

    2018-04-05

    As humans, we have a unique capacity to reflect on our experiences, including emotions. Over time, we develop beliefs about the nature of emotions, and these beliefs are consequential, guiding how we respond to emotions and how we feel as a consequence. One fundamental belief concerns the controllability of emotions: Believing emotions are uncontrollable (entity beliefs) should reduce the likelihood of trying to control emotional experiences using effective regulation strategies like reappraisal; this, in turn, could negatively affect core indices of psychological health, including depressive symptoms. This model holds particular relevance during youth, when emotion-related beliefs first develop and stabilize and when maladaptive beliefs could contribute to emerging risk for depression. In the present investigation, a pilot diary study (N = 223, aged 21-60) demonstrated that entity beliefs were associated with using reappraisal less in everyday life, even when controlling for possible confounds (i.e., self-efficacy, pessimism, stress exposure, stress reactivity). Then, two studies examined whether entity beliefs and associated impairments in reappraisal may set youths on a maladaptive trajectory: In a cross-sectional study (N = 136, aged 14-18), youths with stronger entity beliefs experienced greater depressive symptoms, and this link was mediated by lower reappraisal. This pattern was replicated and extended in a longitudinal study (N = 227, aged 10-18), wherein youth- and parent-reported depressive symptoms were assessed 18 months after assessing beliefs. These results suggest that entity beliefs about emotion constitute a risk factor for depression that acts via reappraisal, adding to the growing literature on emotion beliefs and their consequences for self-regulation and health. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  8. In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.

    Science.gov (United States)

    Matsen, Miles E; Thaler, Joshua P; Wisse, Brent E; Guyenet, Stephan J; Meek, Thomas H; Ogimoto, Kayoko; Cubelo, Alex; Fischer, Jonathan D; Kaiyala, Karl J; Schwartz, Michael W; Morton, Gregory J

    2013-04-01

    Recent advances in human brown adipose tissue (BAT) imaging technology have renewed interest in the identification of BAT activators for the treatment of obesity and diabetes. In uncontrolled diabetes (uDM), activation of BAT is implicated in glucose lowering mediated by intracerebroventricular (icv) administration of leptin, which normalizes blood glucose levels in streptozotocin (STZ)-induced diabetic rats. The potent effect of icv leptin to increase BAT glucose uptake in STZ-diabetes is accompanied by the return of reduced plasma thyroxine (T4) levels and BAT uncoupling protein-1 (Ucp1) mRNA levels to nondiabetic controls. We therefore sought to determine whether activation of thyroid hormone receptors is sufficient in and of itself to lower blood glucose levels in STZ-diabetes and whether this effect involves activation of BAT. We found that, although systemic administration of the thyroid hormone (TR)β-selective agonist GC-1 increases energy expenditure and induces further weight loss in STZ-diabetic rats, it neither increased BAT glucose uptake nor attenuated diabetic hyperglycemia. Even when GC-1 was administered in combination with a β(3)-adrenergic receptor agonist to mimic sympathetic nervous system activation, glucose uptake was not increased in STZ-diabetic rats, nor was blood glucose lowered, yet this intervention potently activated BAT. Similar results were observed in animals treated with active thyroid hormone (T3) instead of GC-1. Taken together, our data suggest that neither returning normal plasma thyroid hormone levels nor BAT activation has any impact on diabetic hyperglycemia, and that in BAT, increases of Ucp1 gene expression and glucose uptake are readily dissociated from one another in this setting.

  9. Damage Control Resuscitation Supplemented with Vasopressin in a Severe Polytrauma Model with Traumatic Brain Injury and Uncontrolled Internal Hemorrhage.

    Science.gov (United States)

    Dickson, J Michael; Wang, Xu; St John, Alexander E; Lim, Esther B; Stern, Susan A; White, Nathan J

    2018-03-14

    Traumatic brain injury (TBI) and hemorrhagic shock (HS) are the leading causes of traumatic death worldwide and particularly on the battlefield. They are especially challenging when present simultaneously (polytrauma), and clear blood pressure end points during fluid resuscitation are not well described for this situation. The goal of this study is to evaluate for any benefit of increasing blood pressure using a vasopressor on brain blood flow during initial fluid resuscitation in a swine polytrauma model. We used a swine polytrauma model with simultaneous TBI, femur fracture, and HS with uncontrolled noncompressible internal bleeding from an aortic tear injury. Five animals were assigned to each of three experimental groups (hydroxyethyl starch only [HES], HES + 0.4 U/kg vasopressin, and no fluid resuscitation [No Fluids]). Fluids were given as two 10 mL/kg boluses according to tactical field care guidelines. Primary outcomes were mean arterial blood pressure (MAP) and brain blood flow at 60 min. Secondary outcomes were blood flows in the heart, intestine, and kidney; arterial blood lactate level; and survival at 6 hr. Organ blood flow was measured using injection of colored microspheres. Five animals were tested in each of the three groups. There was a statistically significant increase in MAP with vasopressin compared with other experimental groups, but no significant increase in brain blood flow during the first 60 min of resuscitation. The vasopressin group also exhibited greater total internal hemorrhage volume and rate. There was no difference in survival at 6 hours. In this experimental swine polytrauma model, increasing blood pressure with vasopressin did not improve brain perfusion, likely due to increased internal hemorrhage. Effective hemostasis should remain the top priority for field treatment of the polytrauma casualty with TBI.

  10. Design of a pragmatic trial in minority children presenting to the emergency department with uncontrolled asthma: The CHICAGO Plan.

    Science.gov (United States)

    Krishnan, Jerry A; Martin, Molly A; Lohff, Cortland; Mosnaim, Giselle S; Margellos-Anast, Helen; DeLisa, Julie A; McMahon, Kate; Erwin, Kim; Zun, Leslie S; Berbaum, Michael L; McDermott, Michael; Bracken, Nina E; Kumar, Rajesh; Margaret Paik, S; Nyenhuis, Sharmilee M; Ignoffo, Stacy; Press, Valerie G; Pittsenbarger, Zachary E; Thompson, Trevonne M

    2017-06-01

    Among children with asthma, black children are two to four times as likely to have an emergency department (ED) visit and die from asthma, respectively, compared to white children in the United States. Despite the availability of evidence-based asthma management guidelines, minority children are less likely than white children to receive or use effective options for asthma care. The CHICAGO Plan is a three-arm multi-center randomized pragmatic trial of children 5 to 11years old presenting to the ED with uncontrolled asthma that compares: [1] an ED-focused intervention to improve the quality of care on discharge to home, [2] the same ED-focused intervention together with a home-based community health worker (CHW)-led intervention, and [3] enhanced usual care. All children receive spacers for the metered dose inhaler and teaching about its use. The Patient-Reported Outcomes Measurement Information System (PROMIS) Asthma Impact Scale and Satisfaction with Participation in Social Roles at 6months are the primary outcomes in children and in caregivers, respectively. Other patient-reported outcomes and indicators of healthcare utilization are assessed as secondary outcomes. Innovative features of the CHICAGO Plan include early and continuous engagement of children, caregivers, the Chicago Department of Public Health, and other stakeholders to inform the design and implementation of the study and a shared research infrastructure to coordinate study activities. The objective of this report is to describe the development of the CHICAGO Plan, including the methods and rationale for engaging stakeholders, the shared research infrastructure, and other features of the pragmatic clinical trial design. Published by Elsevier Inc.

  11. Fevipiprant, an oral prostaglandin DP2 receptor (CRTh2) antagonist, in allergic asthma uncontrolled on low-dose inhaled corticosteroids.

    Science.gov (United States)

    Bateman, Eric D; Guerreros, Alfredo G; Brockhaus, Florian; Holzhauer, Björn; Pethe, Abhijit; Kay, Richard A; Townley, Robert G

    2017-08-01

    Dose-related efficacy and safety of fevipiprant (QAW039), an oral DP 2 (CRTh2) receptor antagonist, was assessed in patients with allergic asthma uncontrolled by low-dose inhaled corticosteroids (ICS).Adult patients were randomised to 12 weeks' treatment with once-daily (1, 3, 10, 30, 50, 75, 150, 300 or 450 mg q.d ) or twice-daily (2, 25, 75 or 150 mg b.i.d ) fevipiprant (n=782), montelukast 10 mg q.d (n=139) or placebo (n=137). All patients received inhaled budesonide 200 μg b.i.d Fevipiprant produced a statistically significant improvement in the primary end-point of change in pre-dose forced expiratory volume in 1 s at week 12 (p=0.0035) with a maximum model-averaged difference to placebo of 0.112 L. The most favourable pairwise comparisons to placebo were for the fevipiprant 150 mg q.d and 75 mg b.i.d groups, with no clinically meaningful differences between q.d and b.i.d Montelukast also demonstrated a significant improvement in this end-point. No impact on other efficacy end-points was observed. Adverse events were generally mild/moderate in severity, and were evenly distributed across doses and treatments.Fevipiprant appears to be efficacious and well-tolerated in this patient population, with an optimum total daily dose of 150 mg. Further investigations into the clinical role of fevipiprant in suitably designed phase III clinical trials are warranted. Copyright ©ERS 2017.

  12. Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia.

    Science.gov (United States)

    Meek, Thomas H; Dorfman, Mauricio D; Matsen, Miles E; Fischer, Jonathan D; Cubelo, Alexis; Kumar, Monica R; Taborsky, Gerald J; Morton, Gregory J

    2015-07-01

    Several lines of evidence implicate excess glucagon secretion in the elevated rates of hepatic glucose production (HGP), hyperglycemia, and ketosis characteristic of uncontrolled insulin-deficient diabetes (uDM), but whether hyperglucagonemia is required for hyperglycemia in this setting is unknown. To address this question, adult male Wistar rats received either streptozotocin (STZ) to induce uDM (STZ-DM) or vehicle and remained nondiabetic. Four days later, animals received daily subcutaneous injections of either the synthetic GLP-1 receptor agonist liraglutide in a dose-escalating regimen to reverse hyperglucagonemia or its vehicle for 10 days. As expected, plasma glucagon levels were elevated in STZ-DM rats, and although liraglutide treatment lowered glucagon levels to those of nondiabetic controls, it failed to attenuate diabetic hyperglycemia, elevated rates of glucose appearance (Ra), or increased hepatic gluconeogenic gene expression. In contrast, it markedly reduced levels of both plasma ketone bodies and hepatic expression of the rate-limiting enzyme involved in ketone body production. To independently confirm this finding, in a separate study, treatment of STZ-DM rats with a glucagon-neutralizing antibody was sufficient to potently lower plasma ketone bodies but failed to normalize elevated levels of either blood glucose or Ra. These data suggest that in rats with uDM, hyperglucagonemia is required for ketosis but not for increased HGP or hyperglycemia. © 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

  13. Comparative risk of renal, cardiovascular, and mortality outcomes in controlled, uncontrolled resistant, and non-resistant hypertension

    Science.gov (United States)

    Sim, John J.; Bhandari, Simran K.; Shi, Jiaxiao; Reynolds, Kristi; Calhoun, David A.; Kalantar-Zadeh, Kamyar; Jacobsen, Steven J.

    2015-01-01

    We sought to compare the risk of end stage renal disease (ESRD), ischemic heart event (IHE), congestive heart failure (CHF), cerebrovascular accident (CVA), and all-cause mortality among 470,386 individuals with resistant and nonresistant hypertension (non-RH). Resistant hypertension (60,327 individuals) was sub-categorized into 2 groups; 23,104 patients with cRH (controlled on 4 or more medicines) and 37,223 patients with uRH (uncontrolled on 3 or more medicines) in a 5 year retrospective cohort study. Cox proportional hazard modeling was used to estimate hazard ratios adjusting for age, gender, race, body mass index, chronic kidney disease (CKD), and co-morbidities. Resistant hypertension (cRH and uRH) compared to non-RH, had multivariable adjusted hazard ratios (95% confidence intervals) of 1.32 (1.27–1.37), 1.24 (1.20–1.28), 1.46 (1.40–1.52), 1.14 (1.10–1.19), and 1.06 (1.03–1.08) for ESRD, IHE, CHF, CVA, and mortality, respectively. Comparison of uRH to cRH had hazard ratios of 1.25 (1.18–1.33), 1.04 (0.99–1.10), 0.94 (0.89–1.01), 1.23 (1.14–1.31), and 1.01 (0.97–1.05) for ESRD, IHE, CHF, CVA, and mortality, respectively. Males and Hispanics had greater risk for ESRD within all 3 cohorts. Resistant hypertension had greater risk for ESRD, IHE, CHF, CVA, and mortality. The risk of ESRD and CVA and were 25% and 23% greater, respectively, in uRH compared to cRH supporting the linkage between blood pressure and both outcomes. PMID:25945406

  14. A Pharmaco-Economic Analyzis of Treating Severe Uncontrolled Child Asthma with Omalizumab — Actual Russian Clinical Practice Data

    Directory of Open Access Journals (Sweden)

    A. S. Kolbin

    2016-01-01

    Full Text Available Background: Omalizumab is the first and yet the only biopreparation for asthma which combines high efficiency and high cost. The clinical-economic expediency of using omalizumab in asthmatic children has not been previously studied in Russia.Objective: Our aim was to evaluate the clinical and economic expediency of using omalizumab as additive treatment (to basic or supporting therapy in children with severe uncontrolled atopic asthma under the Russian economic conditions.Methods: We conducted a mathematical simulation of asthma treatment in children with an increased frequency of hospitalization (9 times per year with an average monthly omalizumab requirement of 558 mg. The model is based on the Markov chain. The model includes direct and non-direct costs. The planning horizons were 2 and 5 years. We analyzed the efficiency and utility of the costs and their influence on the budget. The stability of received data is proven by sensitivity analyzis.Results: Over a 5-year planning horizon the cost of an additional year of quality life (due to using omalizumab was 1,259,185 roubles, while the “society’s solvency” is 1 341 308 roubles (cost utility analizis. It takes 39,820 rubles to prevent one hospitalization with omalizumab over a 5-year planning horizon (cost efficiency analizis, which is comparable to the cost of hospitalization (43,141 rubles. Total costs for treating 100 children with asthma, 7 of which would be treated with omalizumab, were equal to the amount of money which is enough to treat 105 children without omalizumab (analysis of budgetary influence.Conclusion: The analyses of cost efficiency and utility have shown that the strategy of using omalizumab together with standard treatment is economically expedient. Budgetary influence analysis has not detected a significant burden on the budget.

  15. Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study

    Directory of Open Access Journals (Sweden)

    Rodriguez-Lopez Carmen M

    2011-05-01

    Full Text Available Abstract Background Although trazodone is frequently used by fibromyalgia patients, its efficacy on this disease has not been adequately studied. If effective, pregabalin, whose beneficial effects on pain and sleep quality in fibromyalgia have been demonstrated, could complement the antidepressant and anxiolytic effects of trazodone. The aim of the present study was to assess the effectiveness of trazodone alone and in combination with pregabalin in the treatment of fibromyalgia. Methods This was an open-label uncontrolled study. Trazodone, flexibly dosed (50-300 mg/day, was administered to 66 fibromyalgia patients during 12 weeks; 41 patients who completed the treatment accepted to receive pregabalin, also flexibly dosed (75-450 mg/day, added to trazodone treatment for an additional 12-week period. Outcome measures included the Fibromyalgia Impact Questionnaire (FIQ, the Pittsburgh Sleep Quality Index (PSQI, the Beck Depression Inventory (BDI, the Hospital Anxiety and Depression Scale (HADS, the Brief Pain Inventory (BPI, the Short-Form Health Survey (SF-36, and the Patients' Global Improvement scale (PGI. Emergent adverse reactions were recorded. Data were analyzed with repeated measures one-way ANOVA and paired Student's t test. Results Treatment with trazodone significantly improved global fibromyalgia severity, sleep quality, and depression, as well as pain interference with daily activities although without showing a direct effect on bodily pain. After pregabalin combination additional and significant improvements were seen on fibromyalgia severity, depression and pain interference with daily activities, and a decrease in bodily pain was also apparent. During the second phase of the study, only two patients dropped out due to side effects. Conclusions Trazodone significantly improved fibromyalgia severity and associated symptomatology. Its combination with pregabalin potentiated this improvement and the tolerability of the drugs in

  16. Legitimate data in remote monitoring.

    Science.gov (United States)

    Schilling, J D

    2009-01-01

    An approach for ensuring legitimate data transfers of an individual within a remote healthcare solution. Biometric traits and networking are discussed for clarification of the approach. In this approach, a biometric solution is identified as a fingerprint scanner for use in a personal area network of the patient's home. Secure data exchange is acknowledged as a potential weakness in the transferring of patient data within this network. Some options are discussed to ensure security of data for the review by the caregiver. Example approaches regarding legitimacy are identified using a pulse oximeter [1], a blood pressure meter, and a weight scale as the remote patient devices in the remote healthcare solution.

  17. Remote Sensing for Wind Energy

    DEFF Research Database (Denmark)

    Peña, Alfredo; Hasager, Charlotte Bay; Badger, Merete

    The Remote Sensing in Wind Energy report provides a description of several topics and it is our hope that students and others interested will learn from it. The idea behind it began in year 2008 at DTU Wind Energy (formerly Risø) during the first PhD Summer School: Remote Sensing in Wind Energy...... colleagues in the Meteorology and Test and Measurements Sections from DTU Wind Energy in the PhD Summer Schools. We hope to continue adding more topics in future editions and to update and improve as necessary, to provide a truly state-of-the-art ‘guideline’ available for people involved in Remote Sensing...

  18. Remote Lab for Robotics Applications

    Directory of Open Access Journals (Sweden)

    Robinson Jiménez

    2018-01-01

    Full Text Available This article describes the development of a remote lab environment used to test and training sessions for robotics tasks. This environment is made up of the components and devices based on two robotic arms, a network link, Arduino card and Arduino shield for Ethernet, as well as an IP camera. The remote laboratory is implemented to perform remote control of the robotic arms with visual feedback by camera, of the robots actions, where, with a group of test users, it was possible to obtain performance ranges in tasks of telecontrol of up to 92%.

  19. Remote direct memory access

    Science.gov (United States)

    Archer, Charles J.; Blocksome, Michael A.

    2012-12-11

    Methods, parallel computers, and computer program products are disclosed for remote direct memory access. Embodiments include transmitting, from an origin DMA engine on an origin compute node to a plurality target DMA engines on target compute nodes, a request to send message, the request to send message specifying a data to be transferred from the origin DMA engine to data storage on each target compute node; receiving, by each target DMA engine on each target compute node, the request to send message; preparing, by each target DMA engine, to store data according to the data storage reference and the data length, including assigning a base storage address for the data storage reference; sending, by one or more of the target DMA engines, an acknowledgment message acknowledging that all the target DMA engines are prepared to receive a data transmission from the origin DMA engine; receiving, by the origin DMA engine, the acknowledgement message from the one or more of the target DMA engines; and transferring, by the origin DMA engine, data to data storage on each of the target compute nodes according to the data storage reference using a single direct put operation.

  20. The development of the American national standard, ''control of radioactive surface contamination on materials, equipment and facilities to be released for uncontrolled use''

    International Nuclear Information System (INIS)

    Shapiro, J.

    1980-01-01

    The American National Standard, Control of Radioactive Surface Contamination on Materials, Equipment and Facilities to be Released for Uncontrolled Use, was developed under the procedures of ANSI for ANSI Main Committee N13 (Radiation Protection) by a working group of the Health Physics Society Standards Committee. This standard provides criteria for the control of materials, equipment and facilities contaminated with radioactivity proposed to be released for uncontrolled use. Permissible contamination limits are specified as well as methods assessing the levels of contamination. This paper reviews the proceedings of the Subcommittee on Radioactive Surface Contamination, the comments received by reviewers of the standard, the resolution of the committee, and the bases for reaching the final limits, recommendations, and measurement procedures. (H.K.)

  1. Perceptions of diabetes control among physicians and people with type 2 diabetes uncontrolled on basal insulin in Sweden, Switzerland, and the United Kingdom

    DEFF Research Database (Denmark)

    Brod, Meryl; Pfeiffer, Kathryn M; Barnett, Anthony H

    2016-01-01

    Objective A large proportion of people with type 2 diabetes (T2D) remain uncontrolled on basal insulin. Yet, there is limited understanding of how people with uncontrolled type 2 diabetes (PWUD) perceive control and insulin intensification and whether their perceptions differ from those...... of physicians. The purpose of the study was to investigate perceptions of control and views on insulin intensification among physicians and PWUD. Research design and methods Web surveys of 1012 PWUD on basal insulin and 300 physicians were conducted in Sweden, Switzerland, and the United Kingdom. Results...... very/extremely important for deciding whether or not diabetes is well controlled. In contrast PWUD were significantly more likely to place importance on a variety of factors, including energy levels (74.5% vs. 33.0%, p 

  2. An Electronic Adherence Measurement Intervention to Reduce Clinical Inertia in the Treatment of Uncontrolled Hypertension: The MATCH Cluster Randomized Clinical Trial.

    Science.gov (United States)

    Kronish, Ian M; Moise, Nathalie; McGinn, Thomas; Quan, Yan; Chaplin, William; Gallagher, Benjamin D; Davidson, Karina W

    2016-11-01

    To appropriately manage uncontrolled hypertension, clinicians must decide whether blood pressure (BP) is above goal due to a need for additional medication or to medication nonadherence. Yet, clinicians are poor judges of adherence, and uncertainty about adherence may promote inertia with respect to medication modification. We aimed to determine the effect of sharing electronically-measured adherence data with clinicians on the management of uncontrolled hypertension. This was a cluster randomized trial. Twenty-four primary care providers (12 intervention, 12 usual care; cluster units) and 100 patients with uncontrolled hypertension (65 intervention, 35 usual care) were included in the study. At one visit per patient, clinicians in the intervention group received a report summarizing electronically measured adherence to the BP regimen and recommended clinical actions. Clinicians in the control group did not receive a report. The primary outcome was the proportion of visits with appropriate clinical management (i.e., treatment intensification among adherent patients and adherence counseling among nonadherent patients). Secondary outcomes included patient-rated quality of care and communication during the visit. The proportion of visits with appropriate clinical management was higher in the intervention group than the control group (45 out of 65; 69 %) versus (12 out of 35; 34 %; p = 0.001). A higher proportion of adherent patients in the intervention group had their regimen intensified (p = 0.01), and a higher proportion of nonadherent patients in the intervention group received adherence counseling (p = 0.005). Patients in the intervention group were more likely to give their clinician high ratings on quality of care (p = 0.05), and on measures of patient-centered (p = 0.001) and collaborative communication (p = 0.02). Providing clinicians with electronically-measured antihypertensive adherence reports reduces inertia in the management of

  3. Long-term efficacy and safety of omalizumab in patients with persistent uncontrolled allergic asthma: a systematic review and meta-analysis

    OpenAIRE

    Lai, Tianwen; Wang, Shaobin; Xu, Zhiwei; Zhang, Chao; Zhao, Yun; Hu, Yue; Cao, Chao; Ying, Songmin; Chen, Zhihua; Li, Wen; Wu, Bin; Shen, Huahao

    2015-01-01

    Currently, limited information is available to clinicians regarding the long-term efficacy of omalizumab treatment for allergic asthma. In this report, we aimed to (i) systematically review the evidence regarding the long-term efficacy of omalizumab in patients with persistent uncontrolled allergic asthma, and to (ii) discuss the cost-effectiveness evidence published for omalizumab in this patient population. A comprehensive search for randomized controlled trials (RCTs; ?52 weeks) was perfor...

  4. Aircraft Accident Report; Uncontrolled Impact with Terrain, Fine Airlines Flight 101, Douglas DC-8-61, N27UA, Miami, Florida, August 7, 1997

    Science.gov (United States)

    1998-06-16

    Transcolombiana de Carga ATI Air Transport International ATOS Air Transportation Oversight System ATP airline transport pilot CAM cockpit area microphone...495,000 fine against Aero Transcolombiana de Carga (ATC) for operating a DC-8-51 "over the weight limits set forth in its FAA-approved flight manual...PB98-910402 NTSB/AAR-98/02 DCA97MA059 NATIONAL TRANSPORTATION SAFETY BOARD WASHINGTON, D.C. 20594 AIRCRAFT ACCIDENT REPORT c>C== UNCONTROLLED IMPACT

  5. Remote sensing of oil slicks

    Digital Repository Service at National Institute of Oceanography (India)

    Fondekar, S.P.; Rao, L.V.G.

    the drawback of expensive conventional surveying methods. An airborne remote sensing system used for monitoring and surveillance of oil comprises different sensors such as side-looking airborne radar, synthetic aperture radar, infrared/ultraviolet line scanner...

  6. Remote Decommissioning Experiences at Sellafield

    International Nuclear Information System (INIS)

    Brownridge, M.

    2006-01-01

    British Nuclear Group has demonstrated through delivery of significant decommissioning projects the ability to effectively deploy innovative remote decommissioning technologies and deliver cost effective solutions. This has been achieved through deployment and development of off-the-shelf technologies and design of bespoke equipment. For example, the worlds first fully remotely operated Brokk was successfully deployed to enable fully remote dismantling, packaging and export of waste during the decommissioning of a pilot reprocessing facility. British Nuclear Group has also successfully implemented remote decommissioning systems to enable the decommissioning of significant challenges, including dismantling of a Caesium Extraction Facility, Windscale Pile Chimney and retrieval of Plutonium Contaminated Material (PCM) from storage cells. The challenge for the future is to continue to innovate through utilization of the supply chain and deploy off-the-shelf technologies which have been demonstrated in other industry sectors, thus reducing implementation schedules, cost and maintenance. (authors)

  7. Remote sensing technology: symposium proceedings

    International Nuclear Information System (INIS)

    1985-01-01

    Papers were presented in four subject areas: applications of remote sensing; data analysis, digital and analog; acquisition systems; and general. Abstracts of individual items from the conference were prepared separately for the data base

  8. Classification of remotely sensed images

    CSIR Research Space (South Africa)

    Dudeni, N

    2008-10-01

    Full Text Available For this research, the researchers examine various existing image classification algorithms with the aim of demonstrating how these algorithms can be applied to remote sensing images. These algorithms are broadly divided into supervised...

  9. Remote Sensing of Environmental Pollution

    Science.gov (United States)

    North, G. W.

    1971-01-01

    Environmental pollution is a problem of international scope and concern. It can be subdivided into problems relating to water, air, or land pollution. Many of the problems in these three categories lend themselves to study and possible solution by remote sensing. Through the use of remote sensing systems and techniques, it is possible to detect and monitor, and in some cases, identify, measure, and study the effects of various environmental pollutants. As a guide for making decisions regarding the use of remote sensors for pollution studies, a special five-dimensional sensor/applications matrix has been designed. The matrix defines an environmental goal, ranks the various remote sensing objectives in terms of their ability to assist in solving environmental problems, lists the environmental problems, ranks the sensors that can be used for collecting data on each problem, and finally ranks the sensor platform options that are currently available.

  10. Robotics and remote systems applications

    International Nuclear Information System (INIS)

    Rabold, D.E.

    1996-01-01

    This article is a review of numerous remote inspection techniques in use at the Savannah River (and other) facilities. These include: (1) reactor tank inspection robot, (2) californium waste removal robot, (3) fuel rod lubrication robot, (4) cesium source manipulation robot, (5) tank 13 survey and decontamination robots, (6) hot gang valve corridor decontamination and junction box removal robots, (7) lead removal from deionizer vessels robot, (8) HB line cleanup robot, (9) remote operation of a front end loader at WIPP, (10) remote overhead video extendible robot, (11) semi-intelligent mobile observing navigator, (12) remote camera systems in the SRS canyons, (13) cameras and borescope for the DWPF, (14) Hanford waste tank camera system, (15) in-tank precipitation camera system, (16) F-area retention basin pipe crawler, (17) waste tank wall crawler and annulus camera, (18) duct inspection, and (19) deionizer resin sampling

  11. Remote data monitoring for CDF

    International Nuclear Information System (INIS)

    Kippenhan, H.A. Jr.; Lidinsky, W.; Roediger, G.

    1995-11-01

    Remote data monitoring from the physicists' home institutions has become an important issue in large international experiments to ensure high performance of the detectors and high quality of data and scientific results. The CDF experiment is a collaboration of 450 physicists from 36 institutions in the U.S., Japan, Canada, Italy and Taiwan. Future experiments at Fermilab, CERN and elsewhere will be even larger, and will be performed over a period of order 10 years. The ability of collaborators at remote sites to monitor the increasingly complex detectors and feed the results back into the data acquisition process will be of great importance We report on the status and performance of remote monitoring from Japan of the CDF experiment in Batavia Illinois. We also discuss feasibilities for modest Remote Control Rooms

  12. Creatinine plasma at uncontrolled type 2 diabetes mellitus and controlled type 2 diabetes mellitus patients at primary health care in Binjai city, Indonesia

    Science.gov (United States)

    Rusdiana; Savira, M.; Syahputra, M.; Santoso, A.

    2018-03-01

    The aim of the study knowing the comparison creatinine plasma levels at uncontrolled type 2 diabetes mellitus and controlled type 2 diabetes mellitus patients at Primary Health Care in Binjai city of North Sumatera in Indonesia. This cross-sectional study was conductedon 40 type 2 Diabetes Mellitus patients who attended Primary Health Care in Binjai. Patients with age > 40 years old, (both sexes) were included in the study. We recorded different demographic parameter as age, Body Mass Index, Blood Pressure, and personal history status. And we examined the biochemicalparameters including Hba1c, Fasting Blood Sugar Levels (FBL) and creatinine serum. We separated into two groups base on HbA1c test, controlled type 2 diabetes mellitus and uncontrolled type 2 diabetes mellitus. We measured FBL by using the portable measuring instrument, and Thamrin clinical laboratory measured Hba1c, andwe measured creatinine plasmaby spectrophotometry in Biochemistry laboratory. With statistical analysis using T-test found that there was asignificant differencein creatinine plasma levels between uncontrolled type 2 diabetes mellitus with controlled type 2 diabetes mellitus (p<0.005).

  13. Remote sensing for vineyard management

    Science.gov (United States)

    Philipson, W. R.; Erb, T. L.; Fernandez, D.; Mcleester, J. N.

    1980-01-01

    Cornell's Remote Sensing Program has been involved in a continuing investigation to assess the value of remote sensing for vineyard management. Program staff members have conducted a series of site and crop analysis studies. These include: (1) panchromatic aerial photography for planning artificial drainage in a new vineyard; (2) color infrared aerial photography for assessing crop vigor/health; and (3) color infrared aerial photography and aircraft multispectral scanner data for evaluating yield related factors. These studies and their findings are reviewed.

  14. Scale issues in remote sensing

    CERN Document Server

    Weng, Qihao

    2014-01-01

    This book provides up-to-date developments, methods, and techniques in the field of GIS and remote sensing and features articles from internationally renowned authorities on three interrelated perspectives of scaling issues: scale in land surface properties, land surface patterns, and land surface processes. The book is ideal as a professional reference for practicing geographic information scientists and remote sensing engineers as well as a supplemental reading for graduate level students.

  15. Remote sensing and resource exploration

    International Nuclear Information System (INIS)

    El-Baz, F.; Hassan, M.H.A.; Cappellini, V.

    1989-01-01

    The purpose of the Workshop was to study in depth the application of remote sensing technology to the fields of archaeology, astronomy, geography, geology, and physics. Some emphasis was placed on utilizing remote sensing methods and techniques in the search for water, mineral and land resources. The Workshop was attended by 90 people from 35 countries. The proceedings of this meeting includes 15 papers, 12 of them have a separate abstract in the INIS Database. Refs, figs and tabs

  16. Remote interest in the UK

    International Nuclear Information System (INIS)

    Watson, C.

    1993-01-01

    The United Kingdom nuclear industry has moved on from its low-technology solutions to remote handling problems which were popular in the 1950s and 1960s. A change in attitude has occurred which means that users are looking for high-technology solutions to today's remote handling problems. This review focuses on the ways in which their needs are being met and on the demands for future development which they are generating. (UK)

  17. Designing Zoning of Remote Sensing Drones for Urban Applications: a Review

    Science.gov (United States)

    Norzailawati, M. N.; Alias, A.; Akma, R. S.

    2016-06-01

    This paper discusses on-going research related to zoning regulation for the remote sensing drone in the urban applications. Timestamped maps are presented here follow a citation-based approach, where significant information is retrieved from the scientific literature. The emergence of drones in domestic air raises lots understandable issues on privacy, security and uncontrolled pervasive surveillance that require a careful and alternative solution. The effective solution is to adopt a privacy and property rights approach that create a drone zoning and clear drone legislatures. In providing a differential trend to other reviews, this paper is not limited to drones zoning and regulations, but also, discuss on trend remote sensing drones specification in designing a drone zones. Remote sensing drone will specific according to their features and performances; size and endurance, maximum airspeed and altitude level and particular references are made to the drones range. The implementation of laws zoning could lie with the urban planners whereby, a zoning for drone could become a new tactic used to specify areas, where drones could be used, will provide remedies for the harm that arise from drones, and act as a different against irresponsible behaviour. Finally, underlines the need for next regulations on guidelines and standards which can be used as a guidance for urban decision makers to control the drones' operating, thus ensuring a quality and sustainability of resilience cities simultaneously encouraging the revolution of technology.

  18. Remote maintenance development, July 1975--July 1976

    International Nuclear Information System (INIS)

    Fletcher, R.D.

    1977-04-01

    The results of the second year's efforts on remote handling development and studies for remote maintenance of failure-prone areas of the New Waste Calcining Facility (NWCF) are presented. Test arrangements and results for specific viewing situations and component remote installation and removal in the Remote Maintenance Development Facility (RMDF) and component material evaluations are discussed

  19. Remote mechanical C line

    International Nuclear Information System (INIS)

    Nuttall, K.R.; Gardner, P.R.

    1991-01-01

    Westinghouse Hanford Company is developing a desk-top simulation based training program on the operation of the Remote Mechanical C (RMC) Line process in the Plutonium Finishing Plant on the Hanford site, Richland, Washington. Simulations display aod contioually update current values of system parameters on computer graphics of RMC line equipment. Students are able to operate a variety of controllers to maintain proper system status. Programmed faults, selectable by the course instructor, can be used to test student responses to off-normal events. Prior to operation of the simulation, students are given computer-based tutorials on the function, processes, operation, and error conditions associated with individual components. By including the capability of operating each individual component - valves, heaters, agitators, etc. - the computer-based training (CBT) lessons become an interactive training manual. From one perspective RMC represents one step in the diffusion of the well-known and well-documented simulator training activities for nuclear reactor operators to other training programs, equally critical, perhaps, but less well scrutinized in the past. Because of the slowly responding nature of the actual process, RMC can retain many of the capabilities of practice and testing in a simulated work environment while avoiding the cost of a full scale simulator and the exposure and waste developed by practice runs of the RMC line. From another perspective RMC suggests training advances even beyond the most faithful simulators. For example, by integrating CBT lessons with the simulation, RMC permits students to focus in on specific processes occurring inside chosen components. In effect, the interactive training manual is available on-line with the simulation itself. Cost are also discussed

  20. Remote radiation environmental monitoring

    International Nuclear Information System (INIS)

    Pashayev, A.M.; Mehdiyev, A.Sh.; Bayramov, A.A.

    2003-01-01

    Full text: The project of the automated remote monitoring for a level of an environment background radiation in settlements along boundary of the Azerbaijan Republic is developed. The main purpose of the project is: increase of a level of a radiation safety on territory of the Azerbaijan Republic; controlling of a level of an environment background radiation on boundary of the Azerbaijan Republic with the purpose of well-timed warning and acceptance of indispensable measures at probable emergencies on Atomic Power Stations in a number adjacent from Azerbaijan countries, or other ecological catastrophes; controlling of a level of an environment background radiation along eastern suburbs of Azerbaijan regions occupied of Armenia's army and detection of the facts of wrongful disposals of atomic engineering of Armenia on territory of Azerbaijan. As is known, in a number adjacent from Azerbaijan countries the nuclear industry is advanced or develops. It has resulted in origin of threat of a radiation hazard in case of ecological catastrophes: widely scale leakage of radioactive wastes, explosions, or fires on nuclear generating sets, acts of sabotage, directional against Azerbaijan. In this case, at unfavorable meteorological conditions a radioactive waste may be brought by a wind or a rain on territory of Azerbaijan. Measurement is supposed a carry with the help of 'EKOMON' fixed stations. The results of round-the-clock a gamma and a neutron background measurement from the stations will be transmitted automatically to a dispatcher station in the central computer. Established on the stations telescopic sensors also will allow to determine a direction of a radiation and coordinates of radiation source. Stations will be located along boundary, and also in Kedabek, Akstafa, Terter, Agdam and Fizuli regions, and in Autonomous Republic of Nakhichevan

  1. Intermediate and long-term radiological consequences of an uncontrolled access of saline solution into the Asse mine - 59163

    International Nuclear Information System (INIS)

    Ustohalova, Veronika; Kueppers, Christian

    2012-01-01

    The risk of radioactive contamination in the biosphere surrounding the Asse salt mine has been assessed to determine the possible radioactive exposure to humans if the mine collapses. Geological conditions and anthropogenic activities have made the mine instable and allow salt-saturated ground water to seep in. This uncontrolled brine inflow significantly increases the risk of the mine collapsing. If the mine collapses, the brine will be pressed into groundwater, where the radionuclides can migrate into the biosphere and cause radioactive exposure. The key issue discussed in this paper is estimating the short- and long-term radiation burden for humans under several possible scenarios of radionuclide release. Only a radioecological model able to quantify and estimate processes taking place can generate usable results. This work develops the radioecological model describing both radionuclide migration and the resulting radiological exposure along several exposition pathways. Development of the model took into account the sorption processes, solubility limits and special aspects of decay chain migration. The radiological exposure was estimated under non-equilibrated conditions for the case of short-time expositions. At the end of this paper, the model's background, the results of the computations and a comparison of several scenarios will be presented. The estimating short- and long-term radiation burden for humans under several possible scenarios of radionuclide release in the biosphere surrounding the Asse salt mine is the key issue for further planning of suitable decommissioning options. In the case that the mine collapses, the radionuclide can be pressed out into groundwater and migrate into the biosphere. A radioecological model consisting of two independent tools -- radionuclide migration in groundwater ('Migration') and resulting radiological exposure along several pathways ('Exposure') - was developed. The radionuclide migration can be computed with the

  2. V-Go Insulin Delivery System Versus Multiple Daily Insulin Injections for Patients With Uncontrolled Type 2 Diabetes Mellitus.

    Science.gov (United States)

    Winter, Abigail; Lintner, Michaela; Knezevich, Emily

    2015-04-21

    Type 2 diabetes mellitus affects over 29.1 million Americans, diagnosed and undiagnosed. Achieving and maintaining glycemic control for these patients is of extreme importance when working to prevent complications and improve quality of life for patients. The V-Go is a newly developed insulin delivery system. The push of a button inserts a needle into the patient once daily and remains attached for 24 hours. The V-Go is designed to release a set basal rate throughout the day, while allowing patients to provide up to 36 units of on-demand bolus insulin with the manual click of 2 buttons. It is a spring-loaded device filled daily with rapid-acting insulin that runs without the use of batteries or computer software. The main objective of this prospective active comparator study was to observe the A1C lowering effects of multiple daily insulin injections (MDII) versus the use of the V-Go insulin delivery system for patients with uncontrolled type 2 diabetes mellitus over a 3-month period. In addition, the effect on insulin requirement for these patients was assessed with secondary comparisons of weight, blood pressure, prevalence of hypoglycemic events, and quality of life before and after 3 months of intensified insulin therapy with regular monitoring by a clinical pharmacist at an internal medicine clinic. The average A1C lowering experienced by the 3 patients in the V-Go group was 1.5%, while the average A1C change in the 3 patients in the MDII group was an increase of 0.2%. All patients in the V-Go group experienced a decrease in insulin total daily dose (TDD), with an average decrease of 26.3 units. All patients in the MDII group experienced an increase in insulin TDD with an average of 15 units daily to achieve therapeutic goals individualized for each patient. All patients who underwent intensification of insulin therapy experienced an increase in subjective quality of life (QOL) as determined using the Diabetes-39 (D-39) questionnaire, though QOL results lacked

  3. Cost-effectiveness analysis of thiazolidinediones in uncontrolled type 2 diabetic patients receiving sulfonylureas and metformin in Thailand.

    Science.gov (United States)

    Chirakup, Suphachai; Chaiyakunapruk, Nathorn; Chaikledkeaw, Usa; Pongcharoensuk, Petcharat; Ongphiphadhanakul, Boonsong; Roze, Stephane; Valentine, William J; Palmer, Andrew J

    2008-03-01

    The national essential drug committee in Thailand suggested that only one of thiazolidinediones be included in hospital formulary but little was know about their cost-effectiveness values. This study aims to determine an incremental cost-effectiveness ratio of pioglitazone 45 mg compared with rosiglitazone 8 mg in uncontrolled type 2 diabetic patients receiving sulfonylureas and metformin in Thailand. A Markov diabetes model (Center for Outcome Research model) was used in this study. Baseline characteristics of patients were based on Thai diabetes registry project. Costs of diabetes were calculated mainly from Buddhachinaraj hospital. Nonspecific mortality rate and transition probabilities of death from renal replacement therapy were obtained from Thai sources. Clinical effectiveness of thiazolidinediones was retrieved from a meta-analysis. All analyses were based on the government hospital policymaker perspective. Both cost and outcomes were discounted with the rate of 3%. Base-case analyses were analyzed as incremental cost per quality-adjusted life year (QALY) gained. A series of sensitive analyses were performed. In base-case analysis, the pioglitazone group had a better clinical outcomes and higher lifetime costs. The incremental cost per QALY gained was 186,246 baht (US$ 5389). The acceptability curves showed that the probability of pioglitazone being cost-effective was 29% at the willingness to pay of one time of Thai gross domestic product per capita (GDP per capita). The effect of pioglitazone on %HbA1c decrease was the most sensitive to the final outcomes. Our findings showed that in type 2 diabetic patients who cannot control their blood glucose under the combination of sulfonylurea and metformin, the use of pioglitazone 45 mg fell in the cost-effective range recommended by World Health Organization (one to three times of GDP per capita) on average, compared to rosiglitazone 8 mg. Nevertheless, based on sensitivity analysis, its probability of being cost

  4. Flow rate and source reservoir identification from airborne chemical sampling of the uncontrolled Elgin platform gas release

    Science.gov (United States)

    Lee, James D.; Mobbs, Stephen D.; Wellpott, Axel; Allen, Grant; Bauguitte, Stephane J.-B.; Burton, Ralph R.; Camilli, Richard; Coe, Hugh; Fisher, Rebecca E.; France, James L.; Gallagher, Martin; Hopkins, James R.; Lanoiselle, Mathias; Lewis, Alastair C.; Lowry, David; Nisbet, Euan G.; Purvis, Ruth M.; O'Shea, Sebastian; Pyle, John A.; Ryerson, Thomas B.

    2018-03-01

    An uncontrolled gas leak from 25 March to 16 May 2012 led to evacuation of the Total Elgin wellhead and neighbouring drilling and production platforms in the UK North Sea. Initially the atmospheric flow rate of leaking gas and condensate was very poorly known, hampering environmental assessment and well control efforts. Six flights by the UK FAAM chemically instrumented BAe-146 research aircraft were used to quantify the flow rate. The flow rate was calculated by assuming the plume may be modelled by a Gaussian distribution with two different solution methods: Gaussian fitting in the vertical and fitting with a fully mixed layer. When both solution methods were used they compared within 6 % of each other, which was within combined errors. Data from the first flight on 30 March 2012 showed the flow rate to be 1.3 ± 0.2 kg CH4 s-1, decreasing to less than half that by the second flight on 17 April 2012. δ13CCH4 in the gas was found to be -43 ‰, implying that the gas source was unlikely to be from the main high pressure, high temperature Elgin gas field at 5.5 km depth, but more probably from the overlying Hod Formation at 4.2 km depth. This was deemed to be smaller and more manageable than the high pressure Elgin field and hence the response strategy was considerably simpler. The first flight was conducted within 5 days of the blowout and allowed a flow rate estimate within 48 h of sampling, with δ13CCH4 characterization soon thereafter, demonstrating the potential for a rapid-response capability that is widely applicable to future atmospheric emissions of environmental concern. Knowledge of the Elgin flow rate helped inform subsequent decision making. This study shows that leak assessment using appropriately designed airborne plume sampling strategies is well suited for circumstances where direct access is difficult or potentially dangerous. Measurements such as this also permit unbiased regulatory assessment of potential impact, independent of the emitting

  5. The development of remote repairing system, decontamination and in-cell remote inspection equipment

    International Nuclear Information System (INIS)

    Ishibashi, Yuzo; Toyoda, Osamu; Haginoya, Isao; Yamamoto, Ryuichi; Tanaka, Yasumasa

    1993-01-01

    PNC has been developing remote repair and inspection technologies for in-cell components in reprocessing Plants. In this report, several remote technologies such as remote dismantling and removal, decontamination, remote pipe maintenance and remote in-cell inspection equipment are described. (author)

  6. Long-term outcomes of clinical transplantation of pancreatic islets with uncontrolled donors after cardiac death: a multicenter experience in Japan.

    Science.gov (United States)

    Anazawa, T; Saito, T; Goto, M; Kenmochi, T; Uemoto, S; Itoh, T; Yasunami, Y; Kenjo, A; Kimura, T; Ise, K; Tsuchiya, T; Gotoh, M

    2014-01-01

    Pancreatic islet transplantation has emerged as an effective treatment for type 1 diabetes mellitus, but its use is limited due to an insufficient supply of cadaveric pancreata. In Japan, uncontrolled donors after cardiac death (DCD) are not deemed to be suitable for whole-organ pancreatic transplantation, and can provide a source of pancreas for islet transplantation. However, the long-term outcomes and utility of uncontrolled DCD in the clinical setting remain controversial. Here, we summarize the long-term outcomes of islet transplantation employing uncontrolled DCD as reported to the Japan Islet Transplantation Registry. Sixty-four isolations and 34 transplantations of pancreatic islets were conducted in 18 subjects with type 1 diabetes mellitus under the cover of immunosuppression with basiliximab, sirolimus, and tacrolimus. All donors were uncontrolled DCD at the time of harvesting. The mean follow-up time was 76 months. Of the 18 recipients, 8, 4, and 6 recipients received 1, 2, and 3 islet infusions, respectively. Overall graft survivals (defined as a C-peptide level ≥0.3 ng/mL) were 72.2%, 44.4%, and 22.2% at 1, 2, and 5 years, respectively, whereas the corresponding graft survivals after multiple infusions were 90.0%, 70.0%, and 30.0%, respectively. Three of these recipients achieved insulin independence in 14, 79, and 215 days. HbA1c levels and the requirement of exogenous insulin were improved before loss of graft function. All recipients became free of severe hypoglycemia unawareness, however, at least 5 of 14 patients who had graft failure experienced recurrence of severe hypoglycemia after the loss of graft function. Islet transplantation from DCD can relieve glucose instability and problems with hypoglycemia when the graft is functioning. However, islets from uncontrolled DCD may be associated with reduced long-term graft survival. Further improvements in the clinical outcome by modification of islet isolation/transplantation protocols are

  7. Concentration of Endogenous Secretory Receptor for Advanced Glycation End Products and Matrix Gla Protein in Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients

    Directory of Open Access Journals (Sweden)

    Dwi Yuniati Daulay

    2013-04-01

    Full Text Available BACKGROUND: Advanced glycation end products (AGE and their receptor (RAGE system play an important role in the development of diabetic vascular complications. Recently, an endogenous secretory RAGE (esRAGE has been identified as a novel splice variant, which lacks the transmembrane domain and is secreted in human sera. Interestingly, it was reported that esRAGE binds AGE ligands and neutralizes AGE actions. Many studies have reported that diabetes mellitus correlates with vascular calcification event and increases progressively in uncontrolled diabetes. Matrix Gla Protein (MGP is known to act as an inhibitor in vascular calcification. The aim of this study was to observe progress of vascular calcification in uncontrolled diabetes patient by biochemical markers MGP as inhibitor in vascular calcification, via mechanism of AGEs. METHODS: This study was an observational study with cross sectional design on adult type 2 diabetic male patients who were defined by the 2011 Indonesian diabetes mellitus consensus criteria. RESULTS: The results of this study showed that there was a positive significant correlation between esRAGE and HbA1C (r=0.651, p=0.009, and negative correlation between MGP and HbA1C (r=-0.465, p=0.081 in controlled diabetes group. In uncontrolled diabetes group there was a positive significant correlation between MGP and HbA1C (r=0.350, p=0.023, despite the fact esRAGE showed no significant correlation with HbA1C. There was no significant difference in level of esRAGE and MGP in controlled and uncontrolled diabetes group, but MGP showed lower level in uncontrolled diabetes group, contrary to esRAGE that had higher concentration. CONCLUSIONS: In diabetes condition, complications of vascular calcification are caused by the mechanism of increased AGE formation represented by esRAGE. In diabetes control it is very important to keep the blood vessels from complications caused by vascular calcification. KEYWORDS: type 2 diabetes mellitus

  8. Remote sensing in meteorology, oceanography and hydrology

    Energy Technology Data Exchange (ETDEWEB)

    Cracknell, A P [ed.

    1981-01-01

    Various aspects of remote sensing are discussed. Topics include: the EARTHNET data acquisition, processing, and distribution facility the design and implementation of a digital interactive image processing system geometrical aspects of remote sensing and space cartography remote sensing of a complex surface legal aspects of remote sensing remote sensing of pollution, dust storms, ice masses, and ocean waves and currents use of satellite images for weather forecasting. Notes on field trips and work-sheets for laboratory exercises are included.

  9. Uncontrolled hypertension and associated factors among adult hypertensive patients on follow-up at Jimma University Teaching and Specialized Hospital: cross-sectional study

    Directory of Open Access Journals (Sweden)

    Tesfaye B

    2017-03-01

    Full Text Available Bekele Tesfaye,1 Dessalegn Haile,1 Benalfew Lake,1 Tefera Belachew,2 Temamen Tesfaye,3 Habtamu Abera4 1Department of Nursing, College of Health Science, Debre Markos University, Debre Markos, 2Department of Population and Family Health, 3Department of Nursing and Midwifery, College of Health Science, Jimma University, Jimma, 4Department of Nursing and Midwifery, College of Health Sciences, School of Allied Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia Introduction: Hypertension, including poorly controlled blood pressure, is the major global health problem that affects one billion people worldwide. Limited studies have been conducted on prevalence of uncontrolled hypertension and associated factors among adult hypertensive patients in Ethiopia.Objective: The aim of this study was to determine the prevalence of uncontrolled hypertension and associated factors among adult hypertensive patients at Jimma University Teaching and Specialized Hospital.Methods: Institution-based cross-sectional study was conducted at the chronic illness clinic of Jimma University Specialized and Teaching hospital from March 09 to April 13, 2016. A total of 345 hypertensive patients were selected using systematic sampling technique. Data were collected using structured questionnaire through face-to-face exit interview and chart review. Data were analyzed using Statistical Package for the Social Sciences (SPSS version 20.0 software. The bivariate and multivariable analysis was done to identify factors of uncontrolled hypertension.Results: More than half, 52.7%, of the patients had uncontrolled hypertension. Lack of awareness of hypertension-related complications (adjusted odds ratio [AOR]=2.140, 95% confidence interval [CI]=1.272–3.600, p=0.004, nonadherent to smoking abstinence (AOR=3.935, 95% CI=1.065–14.535, p=0.004, nonadherent to alcohol abstinence (AOR=2.477, 95% CI=1.074–5.711, p=033, Khat (Catha edulis chewing (AOR=2.518, 95% CI=1.250–5

  10. Remote monitoring for international safeguards

    International Nuclear Information System (INIS)

    Dupree, S.A.; Sonnier, C.S.

    1999-01-01

    Remote monitoring is not a new technology, and its application to safeguards-relevant activities has been examined for a number of years. On behalf of the U.S. Department of Energy and international partners, remote monitoring systems have been emplaced in nuclear facilities and laboratories in various parts of the world. The experience gained from these Geld trials of remote monitoring systems has shown the viability of the concept of using integrated monitoring systems. Although a wide variety of sensors has been used in the remote monitoring field trials conducted to date, the possible range of instrumentation that might be used has scarcely been touched. As the technology becomes widespread, large amounts of data will become available to inspectors responsible for safeguards activities at the sites. Effective use of remote monitoring will require processing, archiving, presenting, and assessing of these data. To provide reasonable efficiency in the application of this technology, data processing should be done in a careful and organized manner. The problem will be not an issue of poring over scant records but of surviving under a deluge of information made possible by modern technology Fortunately, modem technology, which created the problem of the data glut, is available to come to the assistance of those inundated by data. Apart from the technological problems, one of the most important aspects of remote monitoring is the potential constraint related to the transmission of data out of a facility or beyond national borders. Remote monitoring across national borders can be seriously considered only in the context of a comprehensive, transparent, and open implementation regime. (author)

  11. Remote monitoring in international safeguards

    International Nuclear Information System (INIS)

    Dupree, S.A.; Sonnier, C.S.; Johnson, C.S.

    1996-01-01

    In recent years, technology that permits the integration of monitoring sensors and instruments into a coherent network has become available. Such integrated monitoring systems provide a means for the automatic collection and assessment of sensor signals and instrument readings and for processing such signals and readings in near real time. To gain experience with the new monitoring system technology, the US Department of energy, through bilateral agreements with its international partners, has initiated a project to emplace demonstration systems in various nuclear facilities and conduct field trials of the technology. This effort is the International Remote Monitoring Project. Under this project, remote monitoring systems are being deployed around the world in an incremental manner. Each deployment is different and each offers lessons for improving the performance and flexibility of the technology. Few problems were encountered with the operation of the installations to date, and much has been learned about the operation and use of the new technology. In the future, the authors believe systems for safeguards applications should be capable of being monitored remotely, emphasize the use of sensors, and utilize selective triggering for recording of images. Remote monitoring across national borders can occur only in the context of a cooperative, nonadversarial implementation regime. However, significant technical and policy work remains to be done before widespread safeguards implementation of remote monitoring should be considered. This paper shows that an abundance of technology supports the implementation of integrated and remote monitoring systems. Current field trials of remote monitoring systems are providing practical data and operational experience to aid in the design of tomorrow's systems

  12. Photogrammetry - Remote Sensing and Geoinformation

    Science.gov (United States)

    Lazaridou, M. A.; Patmio, E. N.

    2012-07-01

    Earth and its environment are studied by different scientific disciplines as geosciences, science of engineering, social sciences, geography, etc. The study of the above, beyond pure scientific interest, is useful for the practical needs of man. Photogrammetry and Remote Sensing (defined by Statute II of ISPRS) is the art, science, and technology of obtaining reliable information from non-contact imaging and other sensor systems about the Earth and its environment, and other physical objects and of processes through recording, measuring, analyzing and representation. Therefore, according to this definition, photogrammetry and remote sensing can support studies of the above disciplines for acquisition of geoinformation. This paper concerns basic concepts of geosciences (geomorphology, geology, hydrology etc), and the fundamentals of photogrammetry-remote sensing, in order to aid the understanding of the relationship between photogrammetry-remote sensing and geoinformation and also structure curriculum in a brief, concise and coherent way. This curriculum can represent an appropriate research and educational outline and help to disseminate knowledge in various directions and levels. It resulted from our research and educational experience in graduate and post-graduate level (post-graduate studies relative to the protection of environment and protection of monuments and historical centers) in the Lab. of Photogrammetry - Remote Sensing in Civil Engineering Faculty of Aristotle University of Thessaloniki.

  13. The ITER remote maintenance system

    International Nuclear Information System (INIS)

    Tesini, A.; Palmer, J.

    2008-01-01

    The aim of this paper is to summarize the ITER approach to machine components maintenance. A major objective of the ITER project is to demonstrate that a future power producing fusion device can be maintained effectively and offer practical levels of plant availability. During its operational lifetime, many systems of the ITER machine will require maintenance and modification; this can be achieved using remote handling methods. The need for timely, safe and effective remote operations on a machine as complex as ITER and within one of the world's most hostile remote handling environments represents a major challenge at every level of the ITER Project organization, engineering and technology. The basic principles of fusion reactor maintenance are presented. An updated description of the ITER remote maintenance system is provided. This includes the maintenance equipment used inside the vacuum vessel, inside the hot cell and the hot cell itself. The correlation between the functions of the remote handling equipment, of the hot cell and of the radwaste processing system is also described. The paper concludes that ITER has equipped itself with a good platform to tackle the challenges presented by its own maintenance and upgrade needs

  14. The remote infrared remote control system based on LPC1114

    Science.gov (United States)

    Ren, Yingjie; Guo, Kai; Xu, Xinni; Sun, Dayu; Wang, Li

    2018-05-01

    In view of the shortcomings such as the short control distance of the traditional air conditioner remote controller on the market nowadays and combining with the current smart home new mode "Cloud+ Terminal" mode, a smart home system based on internet is designed and designed to be fully applied to the simple and reliable features of the LPC1114 chip. The controller is added with temperature control module, timing module and other modules. Through the actual test, it achieved remote control air conditioning, with reliability and stability and brought great convenience to people's lives.

  15. Remote sensing of natural phenomena

    Directory of Open Access Journals (Sweden)

    Miodrag D. Regodić

    2014-06-01

    Full Text Available There has always been a need to directly perceive and study the events whose extent is beyond people's possibilities. In order to get new data and to make observations and studying much more objective in comparison with past syntheses - a new method of examination called remote sensing has been adopted. The paper deals with the principles and elements of remote sensing, as well as with the basic aspects of using remote research in examining meteorological (weather parameters and the conditions of the atmosphere. The usage of satellite images is possible in all phases of the global and systematic research of different natural phenomena when airplane and satellite images of different characteristics are used and their analysis and interpretation is carried out by viewing and computer added procedures. Introduction Remote sensing of the Earth enables observing and studying global and local events that occur on it. Satellite images are nowadays used in geology, agriculture, forestry, geodesy, meteorology, spatial and urbanism planning, designing of infrastructure and other objects, protection from natural and technological catastrophes, etc. It it possible to use satellite images in all phases of global and systematic research of different natural phenomena. Basics of remote sensing Remote sensing is a method of the acquisition and interpretation of information about remote objects without making a physical contact with them. The term Daljinska detekcija is a literal translation of the English term Remote Sensing. In French it isTeledetection, in German - Fernerkundung, in Russian - дистанционие иследования. We also use terms such as: remote survailance, remote research, teledetection, remote methods, and distance research. The basic elements included in Remote Sensing are: object, electromagnetic energy, sensor, platform, image, analysis, interpretation and the information (data, fact. Usage of satellite remote research in

  16. Remote Participation tools at TEXTOR

    International Nuclear Information System (INIS)

    Kraemer-Flecken, A.; Krom, J.; Landgraf, B.; Lambertz, H.T.

    2010-01-01

    Remote Participation is a widely used term with different meanings. In the fusion community it has gained an increasing interest with the shut down of small experiments and participation of associations in larger experiments. Also at TEXTOR Remote Participation becomes more and more important with an increasing number of collaborations. At TEXTOR we differentiate between active and passive remote experiment participation. In addition potential users of TEXTOR like to be involved in the experiment preparation phase where the experiment schedule and the availability of diagnostic systems is discussed as well. After an experiment joint groups of users like to share the results and communicate with each other. The final step in publishing the results is also made more transparent for the users in a twofold process. Using a web based pinboard to spread the publication within the user community allows an extensive and early discussion of the results.

  17. Remote field eddy current testing

    International Nuclear Information System (INIS)

    Cheong, Y. M.; Jung, H. K.; Huh, H.; Lee, Y. S.; Shim, C. M.

    2001-03-01

    The state-of-art technology of the remote field eddy current, which is actively developed as an electromagnetic non-destructive testing tool for ferromagnetic tubes, is described. The historical background and recent R and D activities of remote-field eddy current technology are explained including the theoretical development of remote field eddy current, such as analytical and numerical approach, and the results of finite element analysis. The influencing factors for actual applications, such as the effect of frequency, magnetic permeability, receiving sensitivity, and difficulties of detection and classification of defects are also described. Finally, two examples of actual application, 1) the gap measurement between pressure tubes and calandria tube in CANDU reactor and, 2) the detection of defects in the ferromagnetic heat exchanger tubes, are described. The future research efforts are also included

  18. Remote Sensing for Wind Energy

    DEFF Research Database (Denmark)

    The Remote Sensing in Wind Energy Compendium provides a description of several topics and it is our hope that students and others interested will learn from it. The idea behind this compendium began in year 2008 at Risø DTU during the first PhD Summer School: Remote Sensing in Wind Energy. Thus...... in the Meteorology and Test and Measurements Programs from the Wind Energy Division at Risø DTU in the PhD Summer Schools. We hope to add more topics in future editions and to update as necessary, to provide a truly state-of-the-art compendium available for people involved in Remote Sensing in Wind Energy....

  19. The divertor remote maintenance project

    International Nuclear Information System (INIS)

    Maisonnier, D.; Martin, E.; Akou, K.

    2001-01-01

    Remote replacement of the ITER divertor will be required several times during the life of ITER. To facilitate its regular exchange, the divertor is assembled in the ITER vacuum vessel from 60 cassettes. Radial movers transport each cassette along radial rails through the handling ports and into the vessel where a toroidal mover lifts and transports the cassette around a pair of toroidal rails. Once at its final position the cassette is locked to the toroidal rails and is accurately aligned in both poloidal and toroidal directions. A further requirement on the divertor is to minimise the amount of activated waste to be sent to a repository. To this end the cassettes have been designed to allow the remote replacement, in a hot cell, of their plasma facing components. The paper describes the two facilities built at ENEA Brasimone, Italy, whose aim is to demonstrate the reliable remote maintenance of the divertor cassettes. (author)

  20. The divertor remote maintenance project

    International Nuclear Information System (INIS)

    Maisonnier, D.; Martin, E.; Akou, K.

    1999-01-01

    Remote replacement of the ITER divertor will be required several times during the life of ITER. To facilitate its regular exchange, the divertor is assembled in the ITER vacuum vessel from 60 cassettes. Radial movers transport each cassette along radial rails through the handling ports and into the vessel where a toroidal mover lifts and transports the cassette around a pair of toroidal rails. Once at its final position the cassette is locked to the toroidal rails and is accurately aligned in both poloidal and toroidal directions. A further requirement on the divertor is to minimise the amount of activated waste to be sent to a repository. To this end the cassettes have been designed to allow the remote replacement, in a hot cell, of their plasma facing components. The paper describes the two facilities built at ENEA Brasimone, Italy, whose aim is to demonstrate the reliable remote maintenance of the divertor cassettes. (author)

  1. Current perspective on remote sensing

    International Nuclear Information System (INIS)

    Goodman, R.H.

    1992-01-01

    Surveillance and tracking of oil spills has been a feature of most spill response situations for many years. The simplest and most direct method uses visual observations from an aircraft and hand-plotting of the data on a map. This technique has proven adequate for most small spills and for responses in fair weather. As the size of the spill increases or the weather deteriorates, there is a need to augment visual aerial observations with remote sensing methods. Remote sensing and its associated systems are one of the most technically complex and sophisticated elements of an oil spill response. During the past few years, a number of initiatives have been undertaken to use contemporary electronic and computing systems to develop new and improved remote sensing systems

  2. Lighting for remote viewing systems

    International Nuclear Information System (INIS)

    Draper, J.V.

    1984-01-01

    Scenes viewed by television do not provide the same channels of information for judgment of distances as scenes viewed directly, since television eliminates or degrades several depth perception cues. However, it may be possible to improve depth perception of televised scenes by enhancing the information available through depth cues that are available from lighting. A literature survey and expert opinions were integrated to design a remote lighting arrangement which could enhance depth perception of operators performing remote handling operations. This paper describes the lighting arrangement and discusses some of its advantages and disadvantages. 10 references, 2 figures

  3. Servidor d'escriptoris remots

    OpenAIRE

    Cid Solé, Òscar

    2012-01-01

    El projecte que s'ha dut a terme és un estudi introductori del funcionament de la tecnologia NX fent ús d'una eina lliure com és FreeNX. Aquesta tecnologia està destinada a millorar el rendiment dels processos de comunicació que s'estableixen quan volem accedir a un escriptori remot. El resultat d'aquest estudi s'ha plasmat en un appliance que integra el servidor esmentat juntament amb una aplicació que s'ha desenvolupat per a la gestió d'escriptoris remots utilitzant el servidor FreeNX i els...

  4. Lighting for remote viewing systems

    International Nuclear Information System (INIS)

    Draper, J.V.

    1984-01-01

    Scenes viewed by television do not provide the same channels of information for judgement of distances as scenes viewed directly, since television eliminates or degrades several depth perception cues. However, it may be possible to improve depth perception of televised scenes by enhancing the information available through depth cues that are available from lighting. A literature survey and expert opinions were integrated to design a remote lighting arrangement which could enhance depth perception of operators performing remote handling operations. This paper describes the lighting arrangement and discusses some of its advantages and disadvantages. 10 references, 2 figures

  5. Lighting for remote viewing systems

    International Nuclear Information System (INIS)

    Draper, J.V.

    1984-01-01

    Scenes viewed by television do not provide the same channels of information for judgment of distances as scenes viewed directly, since television eliminates or degrades several depth perception cues. However, it may be possible to improve depth perception of televised scenes by enhancing the information available through depth cues that are available from lighting. A literature survey and expert opinions were integrated to design a remote lighting arrangement which could enhance depth perception of operators performing remote handling operations. This paper describes the lighting arrangement and discusses some of its advantages and disadvantages

  6. Lighting for remote viewing systems

    Energy Technology Data Exchange (ETDEWEB)

    Draper, J.V.

    1984-01-01

    Scenes viewed by television do not provide the same channels of information for judgment of distances as scenes viewed directly, since television eliminates or degrades several depth perception cues. However, it may be possible to improve depth perception of televised scenes by enhancing the information available through depth cues that are available from lighting. A literature survey and expert opinions were integrated to design a remote lighting arrangement which could enhance depth perception of operators performing remote handling operations. This paper describes the lighting arrangement and discusses some of its advantages and disadvantages. 10 references, 2 figures.

  7. Lighting for remote viewing systems

    Energy Technology Data Exchange (ETDEWEB)

    Draper, J.V.

    1984-01-01

    Scenes viewed by television do not provide the same channels of information for judgement of distances as scenes viewed directly, since television eliminates or degrades several depth perception cues. However, it may be possible to improve depth perception of televised scenes by enhancing the information available through depth cues that are available from lighting. A literature survey and expert opinions were integrated to design a remote lighting arrangement which could enhance depth perception of operators performing remote handling operations. This paper describes the lighting arrangement and discusses some of its advantages and disadvantages. 10 references, 2 figures.

  8. EXERCISE, MANUAL THERAPY AND POSTURAL RE-EDUCATION FOR UNCONTROLLED EAR TWITCHING AND RELATED IMPAIRMENTS AFTER WHIPLASH INJURY: A CASE REPORT.

    Science.gov (United States)

    Flanders, Kelsey; Feldner, Heather

    2017-10-01

    Whiplash Associated Disorders and the interventions used to remediate them are well documented in physical therapy literature. However, specific interventions for spasms of the neck musculature that also involve constant ear twitching have yet to be addressed. The purpose of this case report is twofold. First, to describe comprehensive physical therapy management and outcomes for a subject with uncontrolled ear twitching and related musculoskeletal impairments, and second, to discuss the physical therapist's approach to evidence-based care when faced with a paucity of literature addressing physical therapy interventions for subjects with uncontrolled ear twitching. The subject was a 14-year-old female who sustained a right anterolateral whiplash injury when struck in the head by a volleyball seven months prior to physical therapy. Beginning five months after that injury, she experienced uncontrolled and constant superior/inferior movement of her right ear (hereafter described in this report as a twitch) in addition to facial and cervical pain from her initial injury. She was unable to participate in high school athletics due to her pain. A multimodal treatment approach including exercise, manual therapy, and postural reeducation was utilized during the subject's episode of care. After eight treatment sessions, the subjects's cervical range of motion and upper extremity strength improved. The reported frequency of ear twitching decreased, as did reports of neck and shoulder pain. In addition, her Neck Disability Index improved from a score of 22, indicating moderate disability, to 9, indicating mild disability and she was able to return to sport activity. With limited research to direct intervention, clinical reasoning was utilized to formulate an effective therapeutic intervention. A combination of manual therapy, exercise, and postural reeducation intervention was effective for this subject and could assist in guiding interventions for similarly unique clinical

  9. Presumed consent for organ preservation in uncontrolled donation after cardiac death in the United States: a public policy with serious consequences

    Directory of Open Access Journals (Sweden)

    Rady Mohamed Y

    2009-09-01

    Full Text Available Abstract Organ donation after cessation of circulation and respiration, both controlled and uncontrolled, has been proposed by the Institute of Medicine as a way to increase opportunities for organ procurement. Despite claims to the contrary, both forms of controlled and uncontrolled donation after cardiac death raise significant ethical and legal issues. Identified causes for concern include absence of agreement on criteria for the declaration of death, nonexistence of universal guidelines for duration before stopping resuscitation efforts and techniques, and assumption of presumed intent to donate for the purpose of initiating temporary organ-preservation interventions when no expressed consent to donate is present. From a legal point of view, not having scientifically valid criteria of cessation of circulation and respiration for declaring death could lead to a conclusion that organ procurement itself is the proximate cause of death. Although the revised Uniform Anatomical Gift Act of 2006 provides broad immunity to those involved in organ-procurement activities, courts have yet to provide an opinion on whether persons can be held liable for injuries arising from the determination of death itself. Preserving organs in uncontrolled donation after cardiac death requires the administration of life-support systems such as extracorporeal membrane oxygenation. These life-support systems can lead to return of signs of life that, in turn, have to be deliberately suppressed by the administration of pharmacological agents. Finally, allowing temporary organ-preservation interventions without expressed consent is inherently a violation of the principle of respect for a person's autonomy. Proponents of organ donation from uncontrolled donation after cardiac death, on the other hand, claim that these nonconsensual interventions enhance respect for autonomy by allowing people, through surrogate decision making, to execute their right to donate organs

  10. Presumed consent for organ preservation in uncontrolled donation after cardiac death in the United States: a public policy with serious consequences

    Science.gov (United States)

    Verheijde, Joseph L; Rady, Mohamed Y; McGregor, Joan

    2009-01-01

    Organ donation after cessation of circulation and respiration, both controlled and uncontrolled, has been proposed by the Institute of Medicine as a way to increase opportunities for organ procurement. Despite claims to the contrary, both forms of controlled and uncontrolled donation after cardiac death raise significant ethical and legal issues. Identified causes for concern include absence of agreement on criteria for the declaration of death, nonexistence of universal guidelines for duration before stopping resuscitation efforts and techniques, and assumption of presumed intent to donate for the purpose of initiating temporary organ-preservation interventions when no expressed consent to donate is present. From a legal point of view, not having scientifically valid criteria of cessation of circulation and respiration for declaring death could lead to a conclusion that organ procurement itself is the proximate cause of death. Although the revised Uniform Anatomical Gift Act of 2006 provides broad immunity to those involved in organ-procurement activities, courts have yet to provide an opinion on whether persons can be held liable for injuries arising from the determination of death itself. Preserving organs in uncontrolled donation after cardiac death requires the administration of life-support systems such as extracorporeal membrane oxygenation. These life-support systems can lead to return of signs of life that, in turn, have to be deliberately suppressed by the administration of pharmacological agents. Finally, allowing temporary organ-preservation interventions without expressed consent is inherently a violation of the principle of respect for a person's autonomy. Proponents of organ donation from uncontrolled donation after cardiac death, on the other hand, claim that these nonconsensual interventions enhance respect for autonomy by allowing people, through surrogate decision making, to execute their right to donate organs. However, the lack of transparency

  11. Remote Sensing of Water Pollution

    Science.gov (United States)

    White, P. G.

    1971-01-01

    Remote sensing, as a tool to aid in the control of water pollution, offers a means of making rapid, economical surveys of areas that are relatively inaccessible on the ground. At the same time, it offers the only practical means of mapping pollution patterns that cover large areas. Detection of oil slicks, thermal pollution, sewage, and algae are discussed.

  12. Remote measurement of atmospheric pollutants

    Science.gov (United States)

    Allario, F.; Hoell, J.; Seals, R. K.

    1979-01-01

    The concentration and vertical distribution of atmospheric ammonia and ozone are remotely sensed, using dual-C02-laser multichannel infrared Heterodyne Spectrometer (1HS). Innovation makes atmospheric pollution measurements possible with nearly-quantum-noise-limited sensitivity and ultrafine spectral resolution.

  13. Adaptive Control Of Remote Manipulator

    Science.gov (United States)

    Seraji, Homayoun

    1989-01-01

    Robotic control system causes remote manipulator to follow closely reference trajectory in Cartesian reference frame in work space, without resort to computationally intensive mathematical model of robot dynamics and without knowledge of robot and load parameters. System, derived from linear multivariable theory, uses relatively simple feedforward and feedback controllers with model-reference adaptive control.

  14. Satellite Remote Sensing: Aerosol Measurements

    Science.gov (United States)

    Kahn, Ralph A.

    2013-01-01

    Aerosols are solid or liquid particles suspended in the air, and those observed by satellite remote sensing are typically between about 0.05 and 10 microns in size. (Note that in traditional aerosol science, the term "aerosol" refers to both the particles and the medium in which they reside, whereas for remote sensing, the term commonly refers to the particles only. In this article, we adopt the remote-sensing definition.) They originate from a great diversity of sources, such as wildfires, volcanoes, soils and desert sands, breaking waves, natural biological activity, agricultural burning, cement production, and fossil fuel combustion. They typically remain in the atmosphere from several days to a week or more, and some travel great distances before returning to Earth's surface via gravitational settling or washout by precipitation. Many aerosol sources exhibit strong seasonal variability, and most experience inter-annual fluctuations. As such, the frequent, global coverage that space-based aerosol remote-sensing instruments can provide is making increasingly important contributions to regional and larger-scale aerosol studies.

  15. Remote input/output station

    CERN Multimedia

    1972-01-01

    A general view of the remote input/output station installed in building 112 (ISR) and used for submitting jobs to the CDC 6500 and 6600. The card reader on the left and the line printer on the right are operated by programmers on a self-service basis.

  16. Remote file inquiry (RFI) system

    Science.gov (United States)

    1975-01-01

    System interrogates and maintains user-definable data files from remote terminals, using English-like, free-form query language easily learned by persons not proficient in computer programming. System operates in asynchronous mode, allowing any number of inquiries within limitation of available core to be active concurrently.

  17. Experiences with remote electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    O' Keefe, Michael A.; Parvin, Bahram

    2002-02-22

    With the advent of a rapidly proliferating international computer network, it became feasible to consider remote operation of instrumentation normally operated locally. For modern electron microscopes, the growing automation and computer control of many instrumental operations facilitated the task of providing remote operation. In order to provide use of NCEM TEMs by distant users, a project was instituted in 1995 to place a unique instrument, a Kratos EM-1500 operating at 1.5MeV, on-line for remote use. In 1996, the Materials Microcharacterization Collaboratory (MMC) was created as a pilot project within the US Department of Energy's DOE2000 program to establish national collaboratories to provide access via the Internet to unique or expensive DOE research facilities as well as to expertise for remote collaboration, experimentation, production, software development, modeling, and measurement. A major LBNL contribution to the MMC was construction of DeepView, a microscope-independent computer-control system that could be ported to other MMC members to provide a common graphical user-interface (GUI) for control of any MMC instrument over the wide area network.

  18. Maintenance of remote reconnaissance vehicle

    International Nuclear Information System (INIS)

    Schein, D.C.

    1985-01-01

    A description is provided of the maintenance program developed for remote reconnaissance vehicles, such as RRV-1, in use at the Three Mile Island Unit 2. The described approach, which is simple, effective, and flexible, helped to make the effort successful. It will be applied to future projects

  19. US remote monitoring operational experience

    International Nuclear Information System (INIS)

    Dupree, S.A.; Sonnier, C.S.

    1997-01-01

    Under international partnerships and bilateral agreements with the U.S. Department of Energy, Sandia National Laboratories, other national laboratories, and international partner organizations have emplaced remote monitoring systems in nuclear facilities and laboratories in various parts of the world for the purpose of conducting field trials of remote monitoring. The purpose of the present report is to review the results from these field trials and draw general conclusions regarding the trials. Many thousands of hours of sensor and system operation have been logged, and data have been retrieved from many locations. In virtually all cases the system components have functioned as intended and data have been successfully collected and transmitted for review. Comparisons between front-end-triggered video and time-lapse video have shown that the triggered record has captured all relevant monitored operations at the various nuclear facilities included in the field trials. We believe the utility and functional reliability of remote monitoring for international safeguards has been shown. However, it should be kept in mind that openness and transparency, including some form of short-notice inspections, are likely to be prerequisites to the safeguards implementation of remote monitoring in any State

  20. Guidelines for Outsourcing Remote Access.

    Science.gov (United States)

    Hassler, Ardoth; Neuman, Michael

    1996-01-01

    Discusses the advantages and disadvantages of outsourcing remote access to campus computer networks and the Internet, focusing on improved service, cost-sharing, partnerships with vendors, supported protocols, bandwidth, scope of access, implementation, support, network security, and pricing. Includes a checklist for a request for proposals on…

  1. Welding method by remote handling

    International Nuclear Information System (INIS)

    Hashinokuchi, Minoru.

    1994-01-01

    Water is charged into a pit (or a water reservoir) and an article to be welded is placed on a support in the pit by remote handling. A steel plate is disposed so as to cover the article to be welded by remote handling. The welding device is positioned to the portion to be welded and fixed in a state where the article to be welded is shielded from radiation by water and the steel plate. Water in the pit is drained till the portion to be welded is exposed to the atmosphere. Then, welding is conducted. After completion of the welding, water is charged again to the pit and the welding device and fixing jigs are decomposed in a state where the article to be welded is shielded again from radiation by water and the steel plate. Subsequently, the steel plate is removed by remote handling. Then, the article to be welded is returned from the pit to a temporary placing pool by remote handling. This can reduce operator's exposure. Further, since the amount of the shielding materials can be minimized, the amount of radioactive wastes can be decreased. (I.N.)

  2. Remote Sensing Wind and Wind Shear System.

    Science.gov (United States)

    Contents: Remote sensing of wind shear and the theory and development of acoustic doppler; Wind studies; A comparison of methods for the remote detection of winds in the airport environment; Acoustic doppler system development; System calibration; Airport operational tests.

  3. Operational Use of Remote Sensing within USDA

    Science.gov (United States)

    Bethel, Glenn R.

    2007-01-01

    A viewgraph presentation of remote sensing imagery within the USDA is shown. USDA Aerial Photography, Digital Sensors, Hurricane imagery, Remote Sensing Sources, Satellites used by Foreign Agricultural Service, Landsat Acquisitions, and Aerial Acquisitions are also shown.

  4. Remote Sensing Best Paper Award 2013

    OpenAIRE

    Prasad Thenkabail

    2013-01-01

    Remote Sensing has started to institute a “Best Paper” award to recognize the most outstanding papers in the area of remote sensing techniques, design and applications published in Remote Sensing. We are pleased to announce the first “Remote Sensing Best Paper Award” for 2013. Nominations were selected by the Editor-in-Chief and selected editorial board members from among all the papers published in 2009. Reviews and research papers were evaluated separately.

  5. Medical Applications of Remote Electronic Browsing.

    Science.gov (United States)

    Chadwick, Joseph

    The purposes of this study are to identify and define viable remote browsing techniques and the requirements for an interactive medical information system that would permit the use of such techniques. The main emphasis is in the areas of: (1) remote viewing of page material; and (2) remote interrogation of fact banks with question-answering…

  6. Remote sensing for agriculture, ecosystems, and hydrology

    International Nuclear Information System (INIS)

    Engman, E.T.

    1998-01-01

    This volume contains the proceedings of SPIE's remote sensing symposium which was held September 22--24, 1998, in Barcelona, Spain. Topics of discussion include the following: calibration techniques for soil moisture measurements; remote sensing of grasslands and biomass estimation of meadows; evaluation of agricultural disasters; monitoring of industrial and natural radioactive elements; and remote sensing of vegetation and of forest fires

  7. Effectiveness of vildagliptin as add-on to metformin monotherapy among uncontrolled type 2 diabetes mellitus patients in a real-world setting.

    Science.gov (United States)

    Melzer Cohen, Cheli; Davis, Carla; Shalev, Varda; Chodick, Gabriel

    2018-01-01

    Vildagliptin is a dipeptidyl peptidase-4 inhibitor commonly used as a dual oral agent with metformin, thiazolidinediones, or sulfonylurea for the treatment of type 2 diabetes mellitus (T2DM). The efficacy of dual therapy with vildagliptin and metformin has been established in randomized controlled trials, but there is little evidence from observational studies. The aims of the present study were to evaluate the effectiveness of vildagliptin as an add-on therapy to metformin in reducing HbA1c and its affects on body weight and blood lipids in a real-life setting. Included in the present retrospective cohort were T2DM patients (n = 345) who were uncontrolled on metformin monotherapy and intensified treatment with vildagliptin. The efficacy of at least 90 days of dual therapy with vildagliptin and metformin in reducing HbA1c levels, as well as changes in blood lipids and body weight, were evaluated. After 180 days (range 90-365 days) from the index date with a mean daily dose of 92 mg vildagliptin, HbA1c was significantly (P vildagliptin in uncontrolled patients on metformin monotherapy is associated with a significant improvement in the control of HbA1c. © 2017 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

  8. Efficacy and safety of sacubitril/valsartan in patients with essential hypertension uncontrolled by olmesartan: A randomized, double-blind, 8-week study.

    Science.gov (United States)

    Cheung, Deanna G; Aizenberg, Diego; Gorbunov, Vladimir; Hafeez, Kudsia; Chen, Chien-Wei; Zhang, Jack

    2018-01-01

    A majority of patients with hypertension fail to achieve blood pressure (BP) control despite treatment with commonly prescribed drugs. This randomized, double-blind phase III trial assessed the superiority of sacubitril/valsartan 200 mg (97/103 mg) to continued olmesartan 20 mg in reducing ambulatory systolic BP after 8-week treatment in patients with mild to moderate essential hypertension uncontrolled with olmesartan 20 mg alone. A total of 376 patients were randomized to receive either sacubitril/valsartan (n = 188) or olmesartan (n = 188). Superior reductions in 24-hour mean ambulatory systolic BP were observed in the sacubitril/valsartan group vs the olmesartan group (-4.3 mm Hg vs -1.1 mm Hg, P sacubitril/valsartan vs olmesartan (P sacubitril/valsartan vs olmesartan. The overall incidence of adverse events was comparable between the groups. Compared with continued olmesartan, sacubitril/valsartan was more effective and generally safe in patients with hypertension uncontrolled with olmesartan 20 mg. ©2018 Wiley Periodicals, Inc.

  9. Long-term efficacy and safety of omalizumab in patients with persistent uncontrolled allergic asthma: a systematic review and meta-analysis

    Science.gov (United States)

    Lai, Tianwen; Wang, Shaobin; Xu, Zhiwei; Zhang, Chao; Zhao, Yun; Hu, Yue; Cao, Chao; Ying, Songmin; Chen, Zhihua; Li, Wen; Wu, Bin; Shen, Huahao

    2015-01-01

    Currently, limited information is available to clinicians regarding the long-term efficacy of omalizumab treatment for allergic asthma. In this report, we aimed to (i) systematically review the evidence regarding the long-term efficacy of omalizumab in patients with persistent uncontrolled allergic asthma, and to (ii) discuss the cost-effectiveness evidence published for omalizumab in this patient population. A comprehensive search for randomized controlled trials (RCTs; ≥52 weeks) was performed, and six studies met our final inclusion criteria (n = 2,749). Omalizumab was associated with significant improvements in quality of life and the Global Evaluation of Treatment Effectiveness. Omalizumab also allowed patients to completely withdraw from inhaled corticosteroid therapy and did not increase the overall incidence of adverse events. However, there was insufficient evidence that omalizumab reduced the incidence of exacerbations, and the cost-effectiveness of omalizumab varied across studies. Our data indicated that omalizumab use for at least 52 weeks in patients with persistent uncontrolled allergic asthma was accompanied by an acceptable safety profile, but it lacked effect on the asthma exacerbations. Use of omalizumab was associated with a higher cost than conventional therapy, but these increases may be cost-effective if the medication is used in patients with severe allergic asthma. PMID:25645133

  10. An evaluation of traditional and emerging remote sensing technologies for the detection of fugitive contamination at selected Superfund hazardous waste sites

    Science.gov (United States)

    Slonecker, E. Terrence; Fisher, Gary B.

    2011-01-01

    This report represents a remote sensing research effort conducted by the U.S. Geological Survey in cooperation with the U.S. Environmental Protection Agency (EPA) for the EPA Office of Inspector General. The objective of this investigation was to explore the efficacy of remote sensing as a technology for postclosure monitoring of hazardous waste sites as defined under the Comprehensive Environmental Response Compensation and Liability Act of 1980 (Public Law 96-510, 42 U.S.C. §9601 et seq.), also known as \\"Superfund.\\" Five delisted Superfund sites in Maryland and Virginia were imaged with a hyperspectral sensor and visited for collection of soil, water, and spectral samples and inspection of general site conditions. This report evaluates traditional and hyperspectral imagery and field spectroscopic measurement techniques in the characterization and analysis of fugitive (anthropogenic, uncontrolled) contamination at previously remediated hazardous waste disposal sites.

  11. ACCURACY DIMENSIONS IN REMOTE SENSING

    Directory of Open Access Journals (Sweden)

    Á. Barsi

    2018-04-01

    Full Text Available The technological developments in remote sensing (RS during the past decade has contributed to a significant increase in the size of data user community. For this reason data quality issues in remote sensing face a significant increase in importance, particularly in the era of Big Earth data. Dozens of available sensors, hundreds of sophisticated data processing techniques, countless software tools assist the processing of RS data and contributes to a major increase in applications and users. In the past decades, scientific and technological community of spatial data environment were focusing on the evaluation of data quality elements computed for point, line, area geometry of vector and raster data. Stakeholders of data production commonly use standardised parameters to characterise the quality of their datasets. Yet their efforts to estimate the quality did not reach the general end-user community running heterogeneous applications who assume that their spatial data is error-free and best fitted to the specification standards. The non-specialist, general user group has very limited knowledge how spatial data meets their needs. These parameters forming the external quality dimensions implies that the same data system can be of different quality to different users. The large collection of the observed information is uncertain in a level that can decry the reliability of the applications. Based on prior paper of the authors (in cooperation within the Remote Sensing Data Quality working group of ISPRS, which established a taxonomy on the dimensions of data quality in GIS and remote sensing domains, this paper is aiming at focusing on measures of uncertainty in remote sensing data lifecycle, focusing on land cover mapping issues. In the paper we try to introduce how quality of the various combination of data and procedures can be summarized and how services fit the users’ needs. The present paper gives the theoretic overview of the issue, besides

  12. Accuracy Dimensions in Remote Sensing

    Science.gov (United States)

    Barsi, Á.; Kugler, Zs.; László, I.; Szabó, Gy.; Abdulmutalib, H. M.

    2018-04-01

    The technological developments in remote sensing (RS) during the past decade has contributed to a significant increase in the size of data user community. For this reason data quality issues in remote sensing face a significant increase in importance, particularly in the era of Big Earth data. Dozens of available sensors, hundreds of sophisticated data processing techniques, countless software tools assist the processing of RS data and contributes to a major increase in applications and users. In the past decades, scientific and technological community of spatial data environment were focusing on the evaluation of data quality elements computed for point, line, area geometry of vector and raster data. Stakeholders of data production commonly use standardised parameters to characterise the quality of their datasets. Yet their efforts to estimate the quality did not reach the general end-user community running heterogeneous applications who assume that their spatial data is error-free and best fitted to the specification standards. The non-specialist, general user group has very limited knowledge how spatial data meets their needs. These parameters forming the external quality dimensions implies that the same data system can be of different quality to different users. The large collection of the observed information is uncertain in a level that can decry the reliability of the applications. Based on prior paper of the authors (in cooperation within the Remote Sensing Data Quality working group of ISPRS), which established a taxonomy on the dimensions of data quality in GIS and remote sensing domains, this paper is aiming at focusing on measures of uncertainty in remote sensing data lifecycle, focusing on land cover mapping issues. In the paper we try to introduce how quality of the various combination of data and procedures can be summarized and how services fit the users' needs. The present paper gives the theoretic overview of the issue, besides selected, practice

  13. Sensitivity analysis in remote sensing

    CERN Document Server

    Ustinov, Eugene A

    2015-01-01

    This book contains a detailed presentation of general principles of sensitivity analysis as well as their applications to sample cases of remote sensing experiments. An emphasis is made on applications of adjoint problems, because they are more efficient in many practical cases, although their formulation may seem counterintuitive to a beginner. Special attention is paid to forward problems based on higher-order partial differential equations, where a novel matrix operator approach to formulation of corresponding adjoint problems is presented. Sensitivity analysis (SA) serves for quantitative models of physical objects the same purpose, as differential calculus does for functions. SA provides derivatives of model output parameters (observables) with respect to input parameters. In remote sensing SA provides computer-efficient means to compute the jacobians, matrices of partial derivatives of observables with respect to the geophysical parameters of interest. The jacobians are used to solve corresponding inver...

  14. Remote sensing and water resources

    CERN Document Server

    Champollion, N; Benveniste, J; Chen, J

    2016-01-01

    This book is a collection of overview articles showing how space-based observations, combined with hydrological modeling, have considerably improved our knowledge of the continental water cycle and its sensitivity to climate change. Two main issues are highlighted: (1) the use in combination of space observations for monitoring water storage changes in river basins worldwide, and (2) the use of space data in hydrological modeling either through data assimilation or as external constraints. The water resources aspect is also addressed, as well as the impacts of direct anthropogenic forcing on land hydrology (e.g. ground water depletion, dam building on rivers, crop irrigation, changes in land use and agricultural practices, etc.). Remote sensing observations offer important new information on this important topic as well, which is highly useful for achieving water management objectives. Over the past 15 years, remote sensing techniques have increasingly demonstrated their capability to monitor components of th...

  15. Systems design for remote healthcare

    CERN Document Server

    Bonfiglio, Silvio

    2014-01-01

    This book provides a multidisciplinary overview of the design and implementation of systems for remote patient monitoring and healthcare. Readers are guided step-by-step through the components of such a system and shown how they could be integrated in a coherent framework for deployment in practice. The authors explain planning from subsystem design to complete integration and deployment, given particular application constraints. Readers will benefit from descriptions of the clinical requirements underpinning the entire application scenario, physiological parameter sensing techniques, information processing approaches and overall, application dependent system integration. Each chapter ends with a discussion of practical design challenges and two case studies are included to provide practical examples and design methods for two remote healthcare systems with different needs. ·         Provides a multi-disciplinary overview of next-generation mobile healthcare system design; ·         Includes...

  16. Connecting Remote Clusters with ATM

    Energy Technology Data Exchange (ETDEWEB)

    Hu, T.C.; Wyckoff, P.S.

    1998-10-01

    Sandia's entry into utilizing clusters of networked workstations is called Computational Plant or CPlant for short. The design of CPlant uses Ethernet to boot the individual nodes, Myrinet to communicate within a node cluster, and ATM to connect between remote clusters. This SAND document covers the work done to enable the use of ATM on the CPlant nodes in the Fall of 1997.

  17. Remote Observational Techniques in Education

    Science.gov (United States)

    Thieman, J.; Mayo, L.

    2002-09-01

    The ability to observe celestial objects remotely is making a major impact into classroom access to astronomical instrumentation previously impossible to encorporate into curriculum. Two programs, Radio Jove and Telescopes In Education have made important contributions in this field. Radio JOVE is an interactive, hands-on, educational activity for learning the scientific method through the medium of radio observations of Jupiter, the Sun, and the galactic radio background. Students build radio receivers from relatively inexpensive non-profit kits (about \\$125 plus shipping) and use them to record data, analyze the data, and share the results with others. Alternatively, for no cost, the students can record and analyze data from remote radio receivers connected to the web. The projects are useful adjuncts to activities in optical observing since students should recognize that we learn about the universe through more than just the optical spectrum. The projects are mini-electronics courses and also teach about charged particles and magnetic fields. The Radio JOVE web site (http://radiojove.gsfc.nasa.gov) should be consulted for further information. The NASA-sponsored Telescopes In Education (TIE) network (http://tie.jpl.nasa.gov) has been wildly successful in engaging the K-12 education community in real-time, hands-on, interactive astronomy activities. Hundreds of schools in the US, Australia, Canada, England, and Japan have participated in the TIE program, remotely controlling the 24-inch telescope at the Mount Wilson Observatory from their classrooms. In recent years, several (approximately 20 to date) other telescopes have been, or are in the process of being, outfitted for remote use as TIE affiliates. These telescopesare integrated seamlessly into one virtual observatory providing the services required to operate this facility, including a scheduling service, tools for data manipulation, an online proposal review environment, an online "Virtual TIE Student Ap J

  18. Remote handling equipment for SNS

    International Nuclear Information System (INIS)

    Poulten, B.H.

    1983-01-01

    This report gives information on the areas of the SNS, facility which become highly radioactive preventing hands-on maintenance. Levels of activity are sufficiently high in the Target Station Area of the SNS, especially under fault conditions, to warrant reactor technology to be used in the design of the water, drainage and ventilation systems. These problems, together with the type of remote handling equipment required in the SNS, are discussed

  19. Remote laboratory with Raspberry Pi

    OpenAIRE

    Dvorščak, Mihael

    2016-01-01

    The thesis is intended for teachers in junior high school and students of technology education in planning innovational and different learning lessons using information and communication technologies and inductive methods. In thesis is represented an indicative layout of the remote laboratory for educational purposes on the basis of the Raspberry Pi computer. Thesis features used hardware components for this theme, Raspberry Pi computer, its development and commonly used peripheral device...

  20. LIDAR and atmosphere remote sensing

    CSIR Research Space (South Africa)

    Venkataraman, S

    2008-05-01

    Full Text Available using state of the art Light Detection And Ranging (LiDAR) instrumentation and other active and passive remote sensing tools. First “Lidar Field Campaign” • 2-day measurement campaign at University of Pretoria • First 23-hour continuous measurement... head2rightCirrus cloud morphology and dynamics. Atmospheric Research in Southern Africa and Indian Ocean (ARSAIO) Slide 24 © CSIR 2008 www.csir.co.za Middle atmosphere dynamics and thermal structure: comparative studies from...

  1. Remote Sensing Information Science Research

    Science.gov (United States)

    Clarke, Keith C.; Scepan, Joseph; Hemphill, Jeffrey; Herold, Martin; Husak, Gregory; Kline, Karen; Knight, Kevin

    2002-01-01

    This document is the final report summarizing research conducted by the Remote Sensing Research Unit, Department of Geography, University of California, Santa Barbara under National Aeronautics and Space Administration Research Grant NAG5-10457. This document describes work performed during the period of 1 March 2001 thorough 30 September 2002. This report includes a survey of research proposed and performed within RSRU and the UCSB Geography Department during the past 25 years. A broad suite of RSRU research conducted under NAG5-10457 is also described under themes of Applied Research Activities and Information Science Research. This research includes: 1. NASA ESA Research Grant Performance Metrics Reporting. 2. Global Data Set Thematic Accuracy Analysis. 3. ISCGM/Global Map Project Support. 4. Cooperative International Activities. 5. User Model Study of Global Environmental Data Sets. 6. Global Spatial Data Infrastructure. 7. CIESIN Collaboration. 8. On the Value of Coordinating Landsat Operations. 10. The California Marine Protected Areas Database: Compilation and Accuracy Issues. 11. Assessing Landslide Hazard Over a 130-Year Period for La Conchita, California Remote Sensing and Spatial Metrics for Applied Urban Area Analysis, including: (1) IKONOS Data Processing for Urban Analysis. (2) Image Segmentation and Object Oriented Classification. (3) Spectral Properties of Urban Materials. (4) Spatial Scale in Urban Mapping. (5) Variable Scale Spatial and Temporal Urban Growth Signatures. (6) Interpretation and Verification of SLEUTH Modeling Results. (7) Spatial Land Cover Pattern Analysis for Representing Urban Land Use and Socioeconomic Structures. 12. Colorado River Flood Plain Remote Sensing Study Support. 13. African Rainfall Modeling and Assessment. 14. Remote Sensing and GIS Integration.

  2. Remote handling in reprocessing plants

    International Nuclear Information System (INIS)

    Streiff, G.

    1984-01-01

    Remote control will be the rule for maintenance in hot cells of future spent fuel reprocessing plants because of the radioactivity level. New handling equipments will be developed and intervention principles defined. Existing materials, recommendations for use and new manipulators are found in the PMDS' documentation. It is also a help in the choice and use of intervention means and a guide for the user [fr

  3. Nuclear reactors in remote earth

    International Nuclear Information System (INIS)

    Garzon, L.; Cavero, A.

    1999-01-01

    Same basic geological principles along with other facts, have allowed us to establish the existence in the remote past (Between 2.5 and 4 x 10''9 years ago) of the uranium deposits and/or uranium mineralized volumes, which be-have as nuclear reactors. A simplified neutronic diffusion model have allowed us to describe the main characteristics of such systems. The obtained results indicate that this phenomenon was a rather frequent fact. (Author) 7 refs

  4. Portuguese Universities Sharing Remote Laboratories

    Directory of Open Access Journals (Sweden)

    Maria Teresa Restivo

    2009-11-01

    Full Text Available This paper describes a pedagogical assignment based on a cooperative work involving teachers/students from two Portuguese universities. As it happens one is the oldest in the country – University of Coimbra (UC - and the other the largest - University of Porto (UP, about 120 km apart. The authors, believing in the relevance of Information and Communication Technologies (ITs in teaching/learning methodologies and in cooperative teaching methods worked together to plan this pedagogical experience and to run it in a one semester course. Students from UC have been introduced to the remote lab at UP and got the first contact with the remote experiments using easily available sound and image resources based on Skype and an IP camera for better image quality. This first contact has been conducted by the first author at UP with support of the second author at UC. The work will describe briefly the remote experiments used, their inclusion in the course at UC, the associated assessment criteria and, finally, student comments.

  5. Experience with Remote Job Execution

    International Nuclear Information System (INIS)

    Lynch, Vickie E.; Cobb, John W; Green, Mark L.; Kohl, James Arthur; Miller, Stephen D.; Ren, Shelly; Smith, Bradford C.; Vazhkudai, Sudharshan S.

    2008-01-01

    The Neutron Science Portal at Oak Ridge National Laboratory submits jobs to the TeraGrid for remote job execution. The TeraGrid is a network of high performance computers supported by the US National Science Foundation. There are eleven partner facilities with over a petaflop of peak computing performance and sixty petabytes of long-term storage. Globus is installed on a local machine and used for job submission. The graphical user interface is produced by java coding that reads an XML file. After submission, the status of the job is displayed in a Job Information Service window which queries globus for the status. The output folder produced in the scratch directory of the TeraGrid machine is returned to the portal with globus-url-copy command that uses the gridftp servers on the TeraGrid machines. This folder is copied from the stage-in directory of the community account to the user's results directory where the output can be plotted using the portal's visualization services. The primary problem with remote job execution is diagnosing execution problems. We have daily tests of submitting multiple remote jobs from the portal. When these jobs fail on a computer, it is difficult to diagnose the problem from the globus output. Successes and problems will be presented

  6. Testbed for remote telepresence research

    Science.gov (United States)

    Adnan, Sarmad; Cheatham, John B., Jr.

    1992-11-01

    Teleoperated robots offer solutions to problems associated with operations in remote and unknown environments, such as space. Teleoperated robots can perform tasks related to inspection, maintenance, and retrieval. A video camera can be used to provide some assistance in teleoperations, but for fine manipulation and control, a telepresence system that gives the operator a sense of actually being at the remote location is more desirable. A telepresence system comprised of a head-tracking stereo camera system, a kinematically redundant arm, and an omnidirectional mobile robot has been developed at the mechanical engineering department at Rice University. This paper describes the design and implementation of this system, its control hardware, and software. The mobile omnidirectional robot has three independent degrees of freedom that permit independent control of translation and rotation, thereby simulating a free flying robot in a plane. The kinematically redundant robot arm has eight degrees of freedom that assist in obstacle and singularity avoidance. The on-board control computers permit control of the robot from the dual hand controllers via a radio modem system. A head-mounted display system provides the user with a stereo view from a pair of cameras attached to the mobile robotics system. The head tracking camera system moves stereo cameras mounted on a three degree of freedom platform to coordinate with the operator's head movements. This telepresence system provides a framework for research in remote telepresence, and teleoperations for space.

  7. TPX remote maintenance and shielding

    International Nuclear Information System (INIS)

    Rennich, M.J.; Nelson, B.E.

    1994-01-01

    The Tokamak Physics Experiment machine design incorporates comprehensive planning for efficient and safe component maintenance. Three programmatic decisions have been made to insure the successful implementation of this objective. First, the tokamak incorporates radiation shielding to reduce activation of components and limit the dose rate to personnel working on the outside of the machine. This allows most of the ex-vessel equipment to be maintained through conventional ''hands-on'' procedures. Second, to the maximum extent possible, low activation materials will be used inside the shielding volume. This resulted in the selection of Titanium (Ti-6Al-4V) for the vacuum vessel and PFC structures. The third decision stipulated that the primary in-vessel components will be replaced or repaired via remote maintenance tools specifically provided for the task. The component designers have been given the responsibility of incorporating maintenance design and for proving the maintainability of the design concepts in full-scale mockup tests prior to the initiation of final fabrication. Remote maintenance of the TPX machine is facilitated by general purpose tools provided by a special purpose design team. Major tools will include an in-vessel transporter, a vessel transfer system and a large component transfer container. In addition, tools such as manipulators and remotely operable impact wrenches will be made available to the component designers by this group. Maintenance systems will also provide the necessary controls for this equipment

  8. Remote sensing for wind energy

    Energy Technology Data Exchange (ETDEWEB)

    Pena, A.; Bay Hasager, C.; Lange, J. [Technical Univ. of Denmark. DTU Wind Energy, DTU Risoe Campus, Roskilde (Denmark) (and others

    2013-06-15

    The Remote Sensing in Wind Energy report provides a description of several topics and it is our hope that students and others interested will learn from it. The idea behind it began in year 2008 at DTU Wind Energy (formerly Risoe) during the first PhD Summer School: Remote Sensing in Wind Energy. Thus it is closely linked to the PhD Summer Schools where state-of-the-art is presented during the lecture sessions. The advantage of the report is to supplement with in-depth, article style information. Thus we strive to provide link from the lectures, field demonstrations, and hands-on exercises to theory. The report will allow alumni to trace back details after the course and benefit from the collection of information. This is the third edition of the report (first externally available), after very successful and demanded first two, and we warmly acknowledge all the contributing authors for their work in the writing of the chapters, and we also acknowledge all our colleagues in the Meteorology and Test and Measurements Sections from DTU Wind Energy in the PhD Summer Schools. We hope to continue adding more topics in future editions and to update and improve as necessary, to provide a truly state-of-the-art 'guideline' available for people involved in Remote Sensing in Wind Energy. (Author)

  9. The JOYO remote monitoring system

    International Nuclear Information System (INIS)

    Damico, Joseph P.; Hashimoto, Yu

    2000-01-01

    The evolution of the personal computer, operating systems and applications software and the Internet has brought drastic change and many benefits worldwide. Remote monitoring systems benefit from computer network and other modern software technologies. The availability of fast, inexpensive and secure communications enables new solutions for monitoring system applications. The JOYO Remote Monitoring System (RMS) utilizes computer network communications and modular software design to provide a distributed integrated solution for monitoring multiple storage locations. This paper describes the remote monitoring system installed at the JOYO Fast Reactor. The system combines sensors, software, and computer network technologies to create a powerful data collection, storage and dissemination capability. The RMS provides a flexible, scalable solution for a variety of applications. The RMS integrates a variety of state of the art technologies from several sources and serves as a test bed for cutting edge technologies that can be shared with outside users. This paper describes the system components and their operation and discusses system benefits. Current activities and future plants for the JOYO RMS will be discussed. (author)

  10. Smart Cards and remote entrusting

    Science.gov (United States)

    Aussel, Jean-Daniel; D'Annoville, Jerome; Castillo, Laurent; Durand, Stephane; Fabre, Thierry; Lu, Karen; Ali, Asad

    Smart cards are widely used to provide security in end-to-end communication involving servers and a variety of terminals, including mobile handsets or payment terminals. Sometime, end-to-end server to smart card security is not applicable, and smart cards must communicate directly with an application executing on a terminal, like a personal computer, without communicating with a server. In this case, the smart card must somehow trust the terminal application before performing some secure operation it was designed for. This paper presents a novel method to remotely trust a terminal application from the smart card. For terminals such as personal computers, this method is based on an advanced secure device connected through the USB and consisting of a smart card bundled with flash memory. This device, or USB dongle, can be used in the context of remote untrusting to secure portable applications conveyed in the dongle flash memory. White-box cryptography is used to set the secure channel and a mechanism based on thumbprint is described to provide external authentication when session keys need to be renewed. Although not as secure as end-to-end server to smart card security, remote entrusting with smart cards is easy to deploy for mass-market applications and can provide a reasonable level of security.

  11. Remote and unattended monitoring techniques

    International Nuclear Information System (INIS)

    Abedin-Zadeh, R.; Whichello, J.

    1998-01-01

    In the last years, there has been a tremendous growth in the number of unattended assay and monitoring systems in the field. These systems have enabled reduced presence of inspectors while increasing the verification coverage. As part of the Strengthened safeguards System and in particular as part of the measures to improve the cost-effectiveness of safeguards, the possibility of remote transfer of authenticated and encrypted video surveillance, seals and radiation sensor data via telephone or special satellite links have been demonstrated and the necessary arrangements and infrastructure have been prepared. The evaluation of field trials of the remote monitoring systems have shown that the systems are effective in monitoring events of safeguards relevance in near real times. The systems are competitive from a cost standpoint when compared to current methods. The reduction of inspection efforts can be realized by application of remote monitoring technique with scheduled inspections and more effectively with the short notice or unannounced random inspections. It is expected that, upon completion of the necessary arrangements with the Member States authorities, the safeguards department will implement the technique widely before the year 2000

  12. Scenarios for remote gas production

    International Nuclear Information System (INIS)

    Tangen, Grethe; Molnvik, Mona J.

    2009-01-01

    The amount of natural gas resources accessible via proven production technology and existing infrastructure is declining. Therefore, smaller and less accessible gas fields are considered for commercial exploitation. The research project Enabling production of remote gas builds knowledge and technology aiming at developing competitive remote gas production based on floating LNG and chemical gas conversion. In this project, scenarios are used as basis for directing research related to topics that affect the overall design and operation of such plants. Selected research areas are safety, environment, power supply, operability and control. The paper summarises the scenario building process as a common effort among research institutes and industry. Further, it documents four scenarios for production of remote gas and outlines how the scenarios are applied to establish research strategies and adequate plans in a multidisciplinary project. To ensure relevance of the scenarios, it is important to adapt the building process to the current problem and the scenarios should be developed with extensive participation of key personnel.

  13. Establishing a learned-helplessness effect paradigm in C57BL/6 mice: behavioural evidence for emotional, motivational and cognitive effects of aversive uncontrollability per se.

    Science.gov (United States)

    Pryce, Christopher R; Azzinnari, Damiano; Sigrist, Hannes; Gschwind, Tilo; Lesch, Klaus-Peter; Seifritz, Erich

    2012-01-01

    Uncontrollability of major life events has been proposed to be central to depression onset and maintenance. The learned helplessness (LH) effect describes a deficit in terminating controllable aversive stimuli in individuals that experienced aversive stimuli as uncontrollable relative to individuals that experienced the same stimuli as controllable. The LH effect translates across species and therefore can provide an objective-valid readout in animal models of depression. Paradigms for a robust LH effect are established and currently applied in rat but there are few reports of prior and current study of the LH effect in mouse. This includes the C57BL/6 mouse, typically the strain of choice for application of molecular-genetic tools in pre-clinical depression research. The aims of this study were to develop a robust paradigm for the LH effect in BL/6 mice, provide evidence for underlying psychological processes, and study the effect of a depression-relevant genotype on the LH effect. The apparatus used for in/escapable electro-shock exposure and escape test was a two-way shuttle arena with continuous automated measurement of locomotion, compartment transfers, e-shock escapes, vertical activity and freezing. Brother-pairs of BL/6 mice were allocated to either escapable e-shocks (ES) or inescapable e-shocks (IS), with escape latencies of the ES brother used as e-shock durations for the IS brother. The standard two-way shuttle paradigm was modified: the central gate was replaced by a raised divider and e-shock escape required transfer to the distal part of the safe compartment. These refinements yielded reduced superstitious, pre-adaptive e-shock transfers in IS mice and thereby increased the LH effect. To obtain a robust LH effect in all brother pairs, pre-screening for minor between-brother ES differences was necessary and did not confound the LH effect. IS mice developed reduced motor responses to e-shock, consistent with a motivational deficit, and absence of a

  14. Screening and Treatment for Subclinical Hypertensive Heart Disease in Emergency Department Patients With Uncontrolled Blood Pressure: A Cost-effectiveness Analysis.

    Science.gov (United States)

    Twiner, Michael J; Marinica, Alexander L; Kuper, Kenneth; Goodman, Allen; Mahn, James J; Burla, Michael J; Brody, Aaron M; Carroll, Justin A; Josiah Willock, Robina; Flack, John M; Nasser, Samar A; Levy, Phillip D

    2017-02-01

    Poorly controlled hypertension (HTN) is extremely prevalent and, if left unchecked, subclinical hypertensive heart disease (SHHD) may ensue leading to conditions such as heart failure. To address this, we designed a multidisciplinary program to detect and treat SHHD in a high-risk, predominantly African American community. The primary objective of this study was to determine the cost-effectiveness of our program. Study costs associated with identifying and treating patients with SHHD were calculated and a sensitivity analysis was performed comparing the effect of four parameters on cost estimates. These included prevalence of disease, effectiveness of treatment (regression of SHHD, reversal of left ventricular hypertrophy [LVH], or blood pressure [BP] control as separate measures), echocardiogram costs, and participant time/travel costs. The parent study for this analysis was a single-center, randomized controlled trial comparing cardiac effects of standard and intense (<120/80 mm Hg) BP goals at 1 year in patients with uncontrolled HTN and SHHD. A total of 149 patients (94% African American) were enrolled, 133 (89%) had SHHD, 123 (93%) of whom were randomized, with 88 (72%) completing the study. Patients were clinically evaluated and medically managed over the course of 1 year with repeated echocardiograms. Costs of these interventions were analyzed and, following standard practices, a cost per quality-adjusted life-year (QALY) less than $50,000 was defined as cost-effective. Total costs estimates for the program ranged from $117,044 to $119,319. Cost per QALY was dependent on SHHD prevalence and the measure of effectiveness but not input costs. Cost-effectiveness (cost per QALY less than $50,000) was achieved when SHHD prevalence exceeded 11.1% for regression of SHHD, 4.7% for reversal of LVH, and 2.9% for achievement of BP control. In this cohort of predominantly African American patients with uncontrolled HTN, SHHD prevalence was high and screening with

  15. Pre-installation empirical testing of room shielding for high dose rate remote afterloaders

    International Nuclear Information System (INIS)

    Klein, E.E.; Grigsby, P.W.; Williamson, J.F.; Meigooni, A.S.

    1993-01-01

    PURPOSE: Many facilities are acquiring high dose rate remote afterloading units. It is economical that these units be placed in existing shielded teletherapy rooms. Scatter-radiation barriers marginally protect uncontrolled areas from a high dose rate source especially in a room that houses a non-dynamic Cobalt-60 unit. In addition the exact thickness and material composition of the barriers are unknown and therefore, a calculation technique may give misleading results. Also, it would be impossible to evaluate an entire wall barrier by taking isolated core samples in order to assist in the calculations. A quick and inexpensive measurement of dose equivalent using a rented high activity 192Ir source evaluates the barriers and locates shielding deficiencies. METHODS AND MATERIALS: We performed transmission calculations for primary and scattered radiation based on National Council on Radiation Protection and Measurements Reports 49 and 51, respectively. We then rented a high activity 21.7 Ci (8.03 x 10(11) Bq) Ir-192 source to assess our existing teletherapy room shielding for adequacy and voids. This source was placed at the proposed location for clinical high dose rate treatment and measurements were performed. RESULTS: No deficiencies were found in controlled areas surrounding the room, but large differences were found between the calculated and measured values. Our survey located a region in the uncontrolled area above the room requiring augmented shielding which was not predicted by the calculations. A canopy shield was designed to potentially augment the shielding in the ceiling direction. CONCLUSION: Pre-installation testing by measurement is an invaluable method for locating shielding deficiencies and avoiding unnecessary enhancement of shielding particularly when there is lack of information of the inherent shielding

  16. Symptom reduction in young people (15 – 30 years) after a brief behavioral intervention for persistent post-concussion symptoms: An uncontrolled study

    DEFF Research Database (Denmark)

    Thastum, Mille; Rask, Charlotte Ulrikka; Næss-Schmidt, Erhard

    2017-01-01

    on principles from cognitive-behavioral therapy and gradual return to activities. The primary treatment objective was to reduce PCS and prevent chronification of symptoms by reducing negative illness perceptions (eg. beliefs that one cannot control the symptoms and that they will persist), and reducing......Background: About 5 – 15 % of patients with concussion experience persistent post-concussion symptoms (PCS) longer than 3 months post-injury. Currently, treatment options are limited, and no evidence-based intervention is available. Recent studies suggest that cognitive and behavioral processes may...... be involved in symptom maintenance. Aim: To explore in an uncontrolled study design: 1) the overall outcome of a newly developed, brief behavioral intervention in young patients (15 – 30 years) with persistent PCS 3 – 6 months after concussion, and 2) the hypothesised mediators, i.e. illness perceptions...

  17. Exploring the selective lactic acid production from food waste in uncontrolled pH mixed culture fermentations using different reactor configurations.

    Science.gov (United States)

    Bonk, Fabian; Bastidas-Oyanedel, Juan-Rodrigo; Yousef, Ahmed F; Schmidt, Jens Ejbye

    2017-08-01

    Carboxylic acid production from food waste by mixed culture fermentation is an important future waste management option. Obstacles for its implementation are the need of pH control, and a broad fermentation product spectrum leading to increased product separation costs. To overcome these obstacles, the selective production of lactic acid (LA) from model food waste by uncontrolled pH fermentation was tested using different reactor configurations. Batch experiments, semi-continuously fed reactors and a percolation system reached LA concentrations of 32, 16 and 15gCOD LA /L, respectively, with selectivities of 93%, 84% and 75% on COD base, respectively. The semi-continuous reactor was dominated by Lactobacillales. Our techno-economic analysis suggests that LA production from food waste can be economically feasible, with LA recovery and low yields remaining as major obstacles. To solve both problems, we successfully applied in-situ product extraction using activated carbon. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Patient-led versus physician-led titration of insulin glargine in patients with uncontrolled type 2 diabetes: a randomized multinational ATLAS study.

    Science.gov (United States)

    Garg, Satish K; Admane, Karim; Freemantle, Nick; Odawara, Masato; Pan, Chang-Yu; Misra, Anoop; Jarek-Martynowa, Iwona R; Abbas-Raza, Syed; Mirasol, Roberto C; Perfetti, Riccardo

    2015-02-01

    Self-adjustment of insulin dose is commonly practiced in Western patients with type 2 diabetes but is usually not performed in Asian patients. This multinational, 24-week, randomized study compared patient-led with physician-led titration of once-daily insulin glargine in Asian patients with uncontrolled type 2 diabetes who were on 2 oral glucose-lowering agents. Patient-led (n = 275) or physician-led (n = 277) subjects followed the same dose-titration algorithm guided by self-monitored fasting blood glucose (FBG; target, 110 mg/dL [6.1 mmol/L]). The primary endpoint was change in mean glycated hemoglobin (HbA1c) at week 24 in the patient-led versus physician-led titration groups. Patient-led titration resulted in a significantly higher drop in HbA1c value at 24 weeks when compared with physician-led titration (-1.40% vs. -1.25%; mean difference, -0.15; 95% confidence interval, -0.29 to 0.00; P = .043). Mean decrease in FBG was greatest in the patient-led group (-2.85 mmol/L vs. -2.48 mmol/L; P = .001). The improvements in HbA1c and FBG were consistent across countries, with similar improvements in treatment satisfaction in both groups. Mean daily insulin dose was higher in the patient-led group (28.9 units vs. 22.2 units; Ptitration achieved near-target blood glucose levels in Asian patients with uncontrolled type 2 diabetes who were on 2 oral glucose-lowering drugs, demonstrating that Asian patients can self-uptitrate insulin dose effectively when guided.

  19. Glucose-reducing effect of the ORMD-0801 oral insulin preparation in patients with uncontrolled type 1 diabetes: a pilot study.

    Directory of Open Access Journals (Sweden)

    Roy Eldor

    Full Text Available The unpredictable behavior of uncontrolled type 1 diabetes often involves frequent swings in blood glucose levels that impact maintenance of a daily routine. An intensified insulin regimen is often unsuccessful, while other therapeutic options, such as amylin analog injections, use of continuous glucose sensors, and islet or pancreas transplantation are of limited clinical use. In efforts to provide patients with a more compliable treatment method, Oramed Pharmaceuticals tested the capacity of its oral insulin capsule (ORMD-0801, 8 mg insulin in addressing this resistant clinical state. Eight Type I diabetes patients with uncontrolled diabetes (HbA1c: 7.5-10% were monitored throughout the 15-day study period by means of a blind continuous glucose monitoring device. Baseline patient blood glucose behavior was monitored and recorded over a five-day pretreatment screening period. During the ensuing ten-day treatment phase, patients were asked to conduct themselves as usual and to self-administer an oral insulin capsule three times daily, just prior to meal intake. CGM data sufficient for pharmacodynamics analyses were obtained from 6 of the 8 subjects. Treatment with ORMD-0801 was associated with a significant 24.4% reduction in the frequencies of glucose readings >200 mg/dL (60.1 ± 7.9% pretreatment vs. 45.4 ± 4.9% during ORMD-0801 treatment; p = 0.023 and a significant mean 16.6% decrease in glucose area under the curve (AUC (66055 ± 5547 mg/dL/24 hours vs. 55060 ± 3068 mg/dL/24 hours, p = 0.023, with a greater decrease during the early evening hours. In conclusion, ORMD-0801 oral insulin capsules in conjunction with subcutaneous insulin injections, well tolerated and effectively reduced glycemia throughout the day.Clinicaltrials.gov NCT00867594.

  20. Cost-effectiveness of omalizumab add-on to standard-of-care therapy in patients with uncontrolled severe allergic asthma in a Brazilian healthcare setting.

    Science.gov (United States)

    Suzuki, Cibele; Lopes da Silva, Nilceia; Kumar, Praveen; Pathak, Purnima; Ong, Siew Hwa

    2017-08-01

    Omalizumab add-on to standard-of-care therapy has proven to be efficacious in severe asthma patients for whom exacerbations cannot be controlled otherwise. Moreover, evidence from different healthcare settings suggests reduced healthcare resource utilization with omalizumab. Based on these findings, this study aimed to assess the cost-effectiveness of the addition of omalizumab to standard-of-care therapy in patients with uncontrolled severe allergic asthma in a Brazilian healthcare setting. A previously published Markov model was adapted using Brazil-specific unit costs to compare the costs and outcomes of the addition of omalizumab to standard-of-care therapy vs standard-of-care therapy alone. Model inputs were largely based on the eXpeRience study. Costs and health outcomes were calculated for lifetime-years and were annually discounted at 5%. Both one-way and probabilistic sensitivity analyses were performed. An additional cost of R$280,400 for 5.20 additional quality-adjusted life-years was estimated with the addition of omalizumab to standard-of-care therapy, resulting in an incremental cost-effectiveness ratio of R$53,890. One-way sensitivity analysis indicated that discount rates, standard-of-care therapy exacerbation rates, and exacerbation-related mortality rates had the largest impact on incremental cost-effectiveness ratios. Assumptions of lifetime treatment adherence and rate of future exacerbations, independent of previous events, might affect the findings. The lack of Brazilian patients in the eXpeRience study may affect the findings, although sample size and baseline characteristics suggest that the modeled population closely resembles Brazilian severe allergic asthma patients. Results indicate that omalizumab as an add-on therapy is more cost-effective than standard-of-care therapy alone for Brazilian patients with uncontrolled severe allergic asthma, based on the World Health Organization's cost-effectiveness threshold of up to 3-times the gross

  1. Relations Between Atherogenic Index of Plasma, Ratio of Small Dense Low Density Lipoprotein/Lecithin Cholesterol Acyl Transferase and Ratio of Small Dense Low Density Lipoprotein/Cholesteryl Ester Transfer Protein of Controlled and Uncontrolled Type 2 DM

    Directory of Open Access Journals (Sweden)

    Ellis Susanti

    2009-08-01

    Full Text Available BACKGROUND: Patients with Diabetes Melitus are proven to be prone to atherosclerosis and coronary heart disease, especially type 2 Diabetes Melitus (T2DM patient who have higher risk and mortality for cardiovascular risk factor. The Dyslipidemia condition is very common in T2DM as one of the risk factors. Diabetic dyslipidemia is marked by the increased triglyceride (TG, low HDL cholesterol (HDL-C, and increased small dense LDL and apolipoprotein B. Therefore the aim of this study is to assess the differential and correlation between Atherogenic Index of Plasma (AIP, ratio of small dense low density lipoprotein (sdLDL/lecithin cholesterol acyl transferase (LCAT and ratio of sdLDL/cholesteryl ester transfer protein (CETP of controlled and uncontrolled T2DM. METHODS: This study was observational with cross sectional design. In total of 72 patients with T2DM consist of 36 controlled and 36 uncontrolled, participated in this study. The serum TG, HDL-C, sdLDL, LCAT and CETP were examined in their relationship with to T2DM risk. RESULTS: The results of the study indicate that the AIP (p<0.001 increase controlled and uncontrolled T2DM and the ratio of sdLDL/CETP (p=0.004, odds ratio of AIP was 4 (95% CI: 1.501-10.658 and odds ratio of sdLDL/CETP ratio was 4 (95% CI: 1.501-10.658 in uncontrolled T2DM. CONCLUSIONS: This study showed that the AIP and ratio of small dense LDL/CETP had a significant correlation with the uncontrolled T2DM. The AIP and ratio of small dense LDL/CETP increase was found at the uncontrolled T2DM to be 4 times greater than the controlled T2DM. KEYWORDS: T2DM, atherosclerosis, atherogenic index of plasma, small dense LDL, LCAT, CETP, ratio of sdLDL/LCAT, ratio of sdLDL/CETP.

  2. Introductory remote sensing principles and concepts principles and concepts

    CERN Document Server

    Gibson, Paul

    2013-01-01

    Introduction to Remote Sensing Principles and Concepts provides a comprehensive student introduction to both the theory and application of remote sensing. This textbook* introduces the field of remote sensing and traces its historical development and evolution* presents detailed explanations of core remote sensing principles and concepts providing the theory required for a clear understanding of remotely sensed images.* describes important remote sensing platforms - including Landsat, SPOT and NOAA * examines and illustrates many of the applications of remotely sensed images in various fields.

  3. Remote Sensing and Reflectance Profiling in Entomology.

    Science.gov (United States)

    Nansen, Christian; Elliott, Norman

    2016-01-01

    Remote sensing describes the characterization of the status of objects and/or the classification of their identity based on a combination of spectral features extracted from reflectance or transmission profiles of radiometric energy. Remote sensing can be benchtop based, and therefore acquired at a high spatial resolution, or airborne at lower spatial resolution to cover large areas. Despite important challenges, airborne remote sensing technologies will undoubtedly be of major importance in optimized management of agricultural systems in the twenty-first century. Benchtop remote sensing applications are becoming important in insect systematics and in phenomics studies of insect behavior and physiology. This review highlights how remote sensing influences entomological research by enabling scientists to nondestructively monitor how individual insects respond to treatments and ambient conditions. Furthermore, novel remote sensing technologies are creating intriguing interdisciplinary bridges between entomology and disciplines such as informatics and electrical engineering.

  4. Remote Inspection, Measurement and Handling for LHC

    CERN Document Server

    Kershaw, K; Coin, A; Delsaux, F; Feniet, T; Grenard, J L; Valbuena, R

    2007-01-01

    Personnel access to the LHC tunnel will be restricted to varying extents during the life of the machine due to radiation, cryogenic and pressure hazards. The ability to carry out visual inspection, measurement and handling activities remotely during periods when the LHC tunnel is potentially hazardous offers advantages in terms of safety, accelerator down time, and costs. The first applications identified were remote measurement of radiation levels at the start of shut-down, remote geometrical survey measurements in the collimation regions, and remote visual inspection during pressure testing and initial machine cool-down. In addition, for remote handling operations, it will be necessary to be able to transmit several real-time video images from the tunnel to the control room. The paper describes the design, development and use of a remotely controlled vehicle to demonstrate the feasibility of meeting the above requirements in the LHC tunnel. Design choices are explained along with operating experience to-dat...

  5. Field experience with remote monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Desrosiers, A.E. [Bartlett Services, Inc., Plymouth, MA (United States)

    1995-03-01

    The Remote Monitoring System (RMS) is a combination of Merlin Gerin detection hardware, digital data communications hardware, and computer software from Bartlett Services, Inc. (BSI) that can improve the conduct of reactor plant operations in several areas. Using the RMS can reduce radiation exposures to radiation protection technicians (RPTs), reduce radiation exposures to plant maintenance and operations personnel, and reduce the time required to complete maintenance and inspections during outages. The number of temporary RPTs required during refueling outages can also be reduced. Data from use of the RMS at a two power plants are presented to illustrate these points.

  6. REMOTE OPERATIONS IN A GLOBAL ACCELERATOR NETWORK

    International Nuclear Information System (INIS)

    PEGGS, S.; SATOGATA, T.; AGARWAL, D.; RICE, D.

    2003-01-01

    The INTRODUCTION to this paper summarizes the history of the Global Accelerator Network (GAN) concept and the recent workshops that discussed the relationship between GAN and Remote Operations. The REMOTE OPERATIONS SCENARIOS section brings out the organizational philosophy embodied in GAN-like and to non-GAN-like scenarios. The set of major TOPICS RAISED AT THE WORKSHOPS are only partially resolved. COLLABORATION TOOLS are described and discussed, followed by examples of REMOTE ACCELERATOR CONTROL PROJECTS around the world

  7. Remote operations in a global accelerator network

    International Nuclear Information System (INIS)

    Peggs, Steve; Satogata, Todd; Agarwal, Deborah; Rice, David

    2003-01-01

    The INTRODUCTION to this paper summarizes the history of the Global Accelerator Network (GAN) concept and the recent workshops that discussed the relationship between GAN and Remote Operations. The REMOTE OPERATIONS SCENARIOS section brings out the organizational philosophy embodied in GAN-like and to non-GAN-like scenarios. The set of major TOPICS RAISED AT THE WORKSHOPS are only partially resolved. COLLABORATION TOOLS are described and discussed, followed by examples of REMOTE ACCELERATOR CONTROL PROJECTS around the world

  8. Adaptable imaging package for remote vehicles

    Directory of Open Access Journals (Sweden)

    Jean-Luc Liardon

    2017-10-01

    Full Text Available An easy-to-customize, low-cost solution for remote imagery is described. The system, denoted ImPROV (Imaging Package for Remote Vehicles, supports multiple cameras, live streaming, long-range encrypted communication using mobile networks, positioning and time-stamped imagery, etc. The adaptability of the system is demonstrated by its deployment on different remotely operated or autonomous vehicles, which include model aircraft, drones, balloon, kite and a submarine.

  9. Basic Remote Sensing Investigations for Beach Reconnaissance.

    Science.gov (United States)

    Progress is reported on three tasks designed to develop remote sensing beach reconnaissance techniques applicable to the benthic, beach intertidal...and beach upland zones. Task 1 is designed to develop remote sensing indicators of important beach composition and physical parameters which will...ultimately prove useful in models to predict beach conditions. Task 2 is designed to develop remote sensing techniques for survey of bottom features in

  10. LWIR Microgrid Polarimeter for Remote Sensing Studies

    Science.gov (United States)

    2010-02-28

    Polarimeter for Remote Sensing Studies 5b. GRANT NUMBER FA9550-08-1-0295 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 1. Scott Tyo 5e. TASK...and tested at the University of Arizona, and preliminary images are shown in this final report. 15. SUBJECT TERMS Remote Sensing , polarimetry 16...7.0 LWIR Microgrid Polarimeter for Remote Sensing Studies J. Scott Tyo College of Optical Sciences University of Arizona Tucson, AZ, 85721 tyo

  11. Development of standard components for remote handling

    International Nuclear Information System (INIS)

    Taguchi, Kou; Kakudate, Satoshi; Nakahira, Masataka; Ito, Akira

    1998-01-01

    The core of Fusion Experimental Reactor consists of various components such as superconducting magnets and forced-cooled in-vessel components, which are remotely maintained due to intense of gamma radiation. Mechanical connectors such as cooling pipe connections, insulation joints and electrical connectors are commonly used for maintenance of these components and have to be standardized in terms of remote handling. This paper describes these mechanical connectors developed as the standard component compatible with remote handling and tolerable for radiation. (author)

  12. Development of standard components for remote handling

    Energy Technology Data Exchange (ETDEWEB)

    Taguchi, Kou; Kakudate, Satoshi; Nakahira, Masataka; Ito, Akira [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-04-01

    The core of Fusion Experimental Reactor consists of various components such as superconducting magnets and forced-cooled in-vessel components, which are remotely maintained due to intense of gamma radiation. Mechanical connectors such as cooling pipe connections, insulation joints and electrical connectors are commonly used for maintenance of these components and have to be standardized in terms of remote handling. This paper describes these mechanical connectors developed as the standard component compatible with remote handling and tolerable for radiation. (author)

  13. Remote inspection system for nuclear power plants

    International Nuclear Information System (INIS)

    Inagaki, K.; Fujii, M.; Doi, A.; Harima, T.

    1977-01-01

    A remote inspection system for nuclear power plants was constructed based on an analysis of inspections performed by an operator on patrol. This system consists of an operator's console and a remote station. The remote station, equipped with five kinds of sensors, is steered along the inspection route by a photoelectric guiding system or may be manually controlled from an operator's console in a main control room. Signals for control and inspection data are multiplexed and transmitted through a coaxial cable

  14. REMOTE OPERATIONS IN A GLOBAL ACCELERATOR NETWORK.

    Energy Technology Data Exchange (ETDEWEB)

    PEGGS,S.; SATOGATA,T.; AGARWAL,D.; RICE,D.

    2003-05-12

    The INTRODUCTION to this paper summarizes the history of the Global Accelerator Network (GAN) concept and the recent workshops that discussed the relationship between GAN and Remote Operations. The REMOTE OPERATIONS SCENARIOS section brings out the organizational philosophy embodied in GAN-like and to non-GAN-like scenarios. The set of major TOPICS RAISED AT THE WORKSHOPS are only partially resolved. COLLABORATION TOOLS are described and discussed, followed by examples of REMOTE ACCELERATOR CONTROL PROJECTS around the world.

  15. The sun and exoplanets: The solitude of man

    Science.gov (United States)

    Kotov, V. A.

    2012-06-01

    Solar pulsations with a period of P 0 = 9600.606(12) were discovered in 1974. A more recent discovery is that planetary distances in the solar system are subject to spatial resonance with the parameter L 0 ≡ cP 0 ≈ 9600 ls and that the P 0 pulsation itself has cosmological significance (coherent cosmic oscillation, or the pace of absolute time of the universe; c is the speed of light). As of June 2011, 552 extrasolar planets have been discovered. Statistical analysis shows that the distribution of the semimajor axes of alien planets does not have L 0 resonance. Moreover, it appears to have no resonance at all. This frustrates the 20th-century hopes for the existence of extraterrestrial civilizations and possible contact with them. They are simply not there. This explanation of the Fermi paradox, or the Great Silence, appears to rest on the triumph of the anthropic principle, which has been successfully implemented by nature within our planetary system. This leads to a vision whereby the cosmos seems to be created specially for us. The scale L 0 indicates that the sun is a special quantum object, where L 0 is a wave function parameter that is not subject to the rational principles of the classical world, but rather follows a peculiar, quantum logic.

  16. La terrible soledad del saber The terrible solitude of knowledge

    Directory of Open Access Journals (Sweden)

    Restrepo Gabriel

    1999-12-01

    Full Text Available Este ensayo glosa uno de los frentes de trabajio mas atines a Jesús A. Bejarano: la historia y el análisis de la ciencia y de las profesiones, en este caso de la economía. El eje de estos comentarios es la relación entre ciencia económica y poder, partiendo de la queja de Bejarano ante la falsa de reflexión critica sobre este tema, y considerando además su parabolavital como un ejemplode tensión dramatica entre saber y poder, dada la estructura política de Colombia.This essay discusses one of Bejarano's favorite fields of study: the history and analysis of science, as applied to economics. The main line of argument is determined by the relation between economic science and power, which in Bejarano' s opinion had not been adequately considered. His life is taken as a parable of the dramatic tension between knowledge and power within the political structure of Colombia.

  17. Evidence for another response to ostracism : Solitude seeking

    NARCIS (Netherlands)

    Ren, D.; Wesselmann, E.; Williams, K.D.

    2016-01-01

    Purpose The purpose of this study is to provide more insight in the ways key users act as knowledge managers and boundary spanners during the enterprise resource planning (ERP) system usage phase. Despite the recognized importance of key users during the implementation phase of an ERP system, little

  18. Remote systems and remote maintenance of a reprocessing plant in Japan

    International Nuclear Information System (INIS)

    Funaya, T.

    1977-01-01

    The design concept and overall maintenance philosophy applied in the Power Reactor and Nuclear Fuel Development Corporation Reprocessing Plant at Tokai-mura, Japan, are briefly introduced. Details on remote systems and remote maintenance in mechanical processing areas are described

  19. Remote maintenance in nuclear fuel reprocessing

    International Nuclear Information System (INIS)

    Herndon, J.N.

    1985-01-01

    Remote maintenance techniques applied in large-scale nuclear fuel reprocessing plants are reviewed with particular attention to the three major maintenance philosophy groupings: contact, remote crane canyon, and remote/contact. Examples are given, and the relative success of each type is discussed. Probable future directions for large-scale reprocessing plant maintenance are described along with advanced manipulation systems for application in the plants. The remote maintenance development program within the Consolidated Fuel Reprocessing Program at the Oak Ridge National Laboratory is also described. 19 refs., 19 figs

  20. Textbooks and technical references for remote sensing

    Science.gov (United States)

    Rudd, R. D.; Bowden, L. W.; Colwell, R. N.; Estes, J. E.

    1980-01-01

    A selective bibliography is presented which cites 89 textbooks, monographs, and articles covering introductory and advanced remote sensing techniques, photointerpretation, photogrammetry, and image processing.

  1. The international remote monitoring project and implication

    International Nuclear Information System (INIS)

    Sonnier, C.S.; Johnson, C.S.

    1994-01-01

    The future of remote monitoring in International Safeguards system is analyzed. Problems of an update on the International Remote Monitoring Project are considered. The Project allows to remotely transmit safeguards-relevant data directly to IAEA from nuclear facilities worldwide. Description of integrated monitoring system (IMS) is given. A key element of state-of-art of IMS is modular nodal system which accepts information from sensors and provides information to both a data storage unit and a transmitter. Remote Monitoring Systems of Australia and Sweden are presented. 3 figs

  2. TPX in-vessel remote maintenance tooling

    International Nuclear Information System (INIS)

    Rennich, M.J.; Silke, G.W.

    1995-01-01

    The Tokamak Physics Experiment (TPX) has used the lessons learned from successful remote maintenance and remote handling facilities to develop both a concept and philosophy for incorporation of remote design from the earliest phases of the project. Initiation of mockup testing during the conceptual design phase leads to significant improvements in the basic maintenance equipment configuration. In addition, remote handling features and capabilities have been incorporated into the design of the plasma-facing components (PFCs) as part of the total PFC design effort

  3. Remote sampling and analysis of highly radioactive samples in shielded boxes

    International Nuclear Information System (INIS)

    Kirpikov, D.A.; Miroshnichenko, I.V.; Pykhteev, O.Yu.

    2010-01-01

    The sampling procedure used for highly radioactive coolant water is associated with high risk of personnel irradiation and uncontrolled radioactive contamination. Remote sample manipulation with provision for proper radiation shielding is intended for safety enhancement of the sampling procedure. The sampling lines are located in an isolated compartment, a shielded box. Various equipment which enables remote or automatic sample manipulation is used for this purpose. The main issues of development of the shielded box equipment intended for a wider ranger of remote chemical analyses and manipulation techniques for highly radioactive water samples are considered in the paper. There were three principal directions of work: Transfer of chemical analysis performed in the laboratory inside the shielded box; Prevalence of computer-aided and remote techniques of highly radioactive sample manipulation inside the shielded box; and, Increase in control over sampling and determination of thermal-hydraulic parameters of the coolant water in the sampling lines. The developed equipment and solutions enable remote chemical analysis in the restricted volume of the shielded box by using ion-chromatographic, amperometrical, fluorimetric, flow injection, phototurbidimetric, conductometric and potentiometric methods. Extent of control performed in the shielded box is determined taking into account the requirements of the regulatory documents as well as feasibility and cost of the technical adaptation of various methods to the shielded box conditions. The work resulted in highly precise determination of more than 15 indexes of the coolant water quality performed in on-line mode in the shielded box. It averages to 80% of the total extent of control performed at the prototype reactor plants. The novel solutions for highly radioactive sample handling are implemented in the shielded box (for example, packaging, sample transportation to the laboratory, volume measurement). The shielded box is

  4. Remote operation system for container

    International Nuclear Information System (INIS)

    Nakahara, Hirotaka; Hayata, Takashi; Kajiyama, Shigeru; Takahashi, Fuminobu

    1998-01-01

    The present invention provides a remote operation system for conducting operation with operation reaction for the inside of a container filled with water (liquid), such as of inner walls and inner structural materials of a BWR type reactor. Namely, a swimming robot comprises a swimming device swimming in the liquid and an attaching/detaching device for holding/releasing the handling robot. A control device remotely operate the swimming robot and the handling robot by way of a cable. A cable processing device takes up or dispenses the cable. In addition, when the swimming robot grasps the handling robot by the attaching/detaching device, the swimming robot transmits an operation instruction sent from the control device by way of the cable to the handling robot. After the attaching/detaching device of the swimming robot releases the handling robot, the handling robot operates based on the transmitted operation instruction. It is preferable that the handling robot has an adsorptive moving device for moving itself while being adsorbed on the wall surface of the container. (I.S.)

  5. Data Quality in Remote Sensing

    Science.gov (United States)

    Batini, C.; Blaschke, T.; Lang, S.; Albrecht, F.; Abdulmutalib, H. M.; Barsi, Á.; Szabó, G.; Kugler, Zs.

    2017-09-01

    The issue of data quality (DQ) is of growing importance in Remote Sensing (RS), due to the widespread use of digital services (incl. apps) that exploit remote sensing data. In this position paper a body of experts from the ISPRS Intercommission working group III/IVb "DQ" identifies, categorises and reasons about issues that are considered as crucial for a RS research and application agenda. This ISPRS initiative ensures to build on earlier work by other organisations such as IEEE, CEOS or GEO, in particular on the meritorious work of the Quality Assurance Framework for Earth Observation (QA4EO) which was established and endorsed by the Committee on Earth Observation Satellites (CEOS) but aims to broaden the view by including experts from computer science and particularly database science. The main activities and outcomes include: providing a taxonomy of DQ dimensions in the RS domain, achieving a global approach to DQ for heterogeneous-format RS data sets, investigate DQ dimensions in use, conceive a methodology for managing cost effective solutions on DQ in RS initiatives, and to address future challenges on RS DQ dimensions arising in the new era of the big Earth data.

  6. Remote Laser Diffraction PSD Analyzer

    International Nuclear Information System (INIS)

    Batcheller, T.A.; Huestis, G.M.; Bolton, S.M.

    2000-01-01

    Particle size distribution (PSD) analysis of radioactive slurry samples were obtained using a modified off-the-shelf classical laser light scattering particle size analyzer. A Horiba Instruments Inc. Model La-300 PSD analyzer, which has a 0.1 to 600 micron measurement range, was modified for remote application in a hot cell (gamma radiation) environment. The general details of the modifications to this analyzer are presented in this paper. This technology provides rapid and simple PSD analysis, especially down in the fine and microscopic particle size regime. Particle size analysis of these radioactive slurries down in this smaller range was not achievable - making this technology far superior than the traditional methods used previously. Remote deployment and utilization of this technology is in an exploratory stage. The risk of malfunction in this radiation environment is countered by gaining of this tremendously useful fundamental engineering data. Successful acquisition of this data, in conjunction with other characterization analyses, provides important information that can be used in the myriad of potential radioactive waste management alternatives

  7. Taiwan's second remote sensing satellite

    Science.gov (United States)

    Chern, Jeng-Shing; Ling, Jer; Weng, Shui-Lin

    2008-12-01

    FORMOSAT-2 is Taiwan's first remote sensing satellite (RSS). It was launched on 20 May 2004 with five-year mission life and a very unique mission orbit at 891 km altitude. This orbit gives FORMOSAT-2 the daily revisit feature and the capability of imaging the Arctic and Antarctic regions due to the high enough altitude. For more than three years, FORMOSAT-2 has performed outstanding jobs and its global effectiveness is evidenced in many fields such as public education in Taiwan, Earth science and ecological niche research, preservation of the world heritages, contribution to the International Charter: space and major disasters, observation of suspected North Korea and Iranian nuclear facilities, and scientific observation of the atmospheric transient luminous events (TLEs). In order to continue the provision of earth observation images from space, the National Space Organization (NSPO) of Taiwan started to work on the second RSS from 2005. This second RSS will also be Taiwan's first indigenous satellite. Both the bus platform and remote sensing instrument (RSI) shall be designed and manufactured by NSPO and the Instrument Technology Research Center (ITRC) under the supervision of the National Applied Research Laboratories (NARL). Its onboard computer (OBC) shall use Taiwan's indigenous LEON-3 central processing unit (CPU). In order to achieve cost effective design, the commercial off the shelf (COTS) components shall be widely used. NSPO shall impose the up-screening/qualification and validation/verification processes to ensure their normal functions for proper operations in the severe space environments.

  8. Remote Laser Diffraction PSD Analyzer

    International Nuclear Information System (INIS)

    Batcheller, Thomas Aquinas; Huestis, Gary Michael; Bolton, Steven Michael

    2000-01-01

    Particle size distribution (PSD) analysis of radioactive slurry samples were obtained using a modified ''off-the-shelf'' classical laser light scattering particle size analyzer. A Horiba Instruments Inc. Model La-300 PSD analyzer, which has a 0.1 to 600 micron measurement range, was modified for remote application in a ''hot cell'' (gamma radiation) environment. The general details of the modifications to this analyzer are presented in this paper. This technology provides rapid and simple PSD analysis, especially down in the fine and microscopic particle size regime. Particle size analysis of these radioactive slurries down in this smaller range was not achievable--making this technology far superior than the traditional methods used previously. Remote deployment and utilization of this technology is in an exploratory stage. The risk of malfunction in this radiation environment is countered by gaining of this tremendously useful fundamental engineering data. Successful acquisition of this data, in conjunction with other characterization analyses, provides important information that can be used in the myriad of potential radioactive waste management alternatives

  9. Remote handling procedures in JET

    International Nuclear Information System (INIS)

    Raimondi, T.; Huguet, M.

    1976-01-01

    Remote maintenance will be needed in the second phase of operation due to the structural activation produced by deuterium-tritium discharges. Priority will be given to tasks which require frequent intervention, but efforts will be made also to tackle larger operations such as replacement of an octant. Owing to the variety and unpredictability of the operations which may be required, general purpose telemanipulator and TV systems will be used, mounted on versatile articulated supports capable of reaching the various parts of the machine. An experimental programme is planned to test the envisaged equipment and develop procedures for carrying out the various tasks as they are more clearly identified. Design of peripheral equipment for easy accessibility, choice of simple connection methods, development of auxiliary tools, as well as careful programming of the operations, will be essential for successful remote maintenance. The effort put into these areas will, however, also result in considerable time saving during the assembly and maintenance in non-active conditions. Preliminary feasibility tests of some difficult operations have already been done with a force-reflecting servo-manipulator and two TV sets for front and side viewing. Leak identification and precision welding for vacuum tightness were demonstrated

  10. A proposed configuration for remote current measurements

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, A.; Desai, R.G.P.

    stream_size 9 stream_content_type text/plain stream_name 5_Int_Symp_Acoust_Remote_Sens_Proc_1990_230.pdf.txt stream_source_info 5_Int_Symp_Acoust_Remote_Sens_Proc_1990_230.pdf.txt Content-Encoding ISO-8859-1 Content-Type text...

  11. Developing equipment for AGR remote visual inspection

    International Nuclear Information System (INIS)

    James, P.W.; Walton, P.J.

    1985-01-01

    The Remote Inspection Group is part of the CEGB's Generation Development and Construction Division, and has responsibility for the design, development, procurement, testing and setting to work of the equipment provided to carry out routine remote visual inspections of its AGRs. This equipment includes both the viewing devices and the necessary placement equipment. (author)

  12. Project THEMIS: A Center for Remote Sensing.

    Science.gov (United States)

    This report summarizes the technical work accomplished under Project THEMIS, A Center for Remote Sensing at the University of Kansas during the...period 16 September 1967 through 15 September 1973. The highlights of the four major areas forming the remote sensing system are presented. A detailed description of the latest radar spectrometer results is presented.

  13. Remote Laboratories: Bridging University to Secondary Schools

    Directory of Open Access Journals (Sweden)

    Horácio Fernandes

    2012-01-01

    Full Text Available e-lab is a remote laboratory infrastructure powered by a software framework that allows the operation and data retrieve from a remote apparatus. In this demonstration we will present the e-lab interface properties and its modus operandi, giving as well some topics of complimentary software use for data interpretation and analysis.

  14. Time Patterns in Remote OPAC Use.

    Science.gov (United States)

    Lucas, Thomas A.

    1993-01-01

    Describes a transaction log analysis of the New York Public Library research libraries' OPAC (online public access catalog). Much of the remote searching occurred when the libraries were closed and was more evenly distributed than internal searching, demonstrating that remote searching could expand access and reduce peak system loads. (Contains…

  15. REMOTE SENSING FOR ENVIRONMENTAL COMPLIANCE MONITORING

    Science.gov (United States)

    I. Remote Sensing Basics A. The electromagnetic spectrum demonstrates what we can see both in the visible and beyond the visible part of the spectrum through the use of various types of sensors. B. Resolution refers to what a remote sensor can see and how often. 1. Sp...

  16. Remote fabrication of breeder reactor fuel

    International Nuclear Information System (INIS)

    Gerber, E.W.; Hoitink, N.C.; Graham, R.A.

    1984-06-01

    The Secure Automated Fabrication (SAF) Line, a remotely operable plutonium fuel fabrication facility, incorporates advanced automation techniques. Included in the plant are 24 robots used to perform complex operations, and to enhance equipment standardization and ease of maintenance. Automated equipment is controlled remotely from centrally located supervisory computer control consoles or alternatively from control consoles dedicated to individual systems

  17. Red Dirt Thinking on Remote Educational Advantage

    Science.gov (United States)

    Guenther, John; Bat, Melodie; Osborne, Sam

    2014-01-01

    The discourse of remote education is often characterised by a rhetoric of disadvantage. This is reflected in statistics that on the surface seem unambiguous in their demonstration of poor outcomes for remote Aboriginal and Torres Strait Islander students. A range of data support this view, including National Assessment Program-Literacy and…

  18. Remote Monitoring of Cardiac Implantable Electronic Devices.

    Science.gov (United States)

    Cheung, Christopher C; Deyell, Marc W

    2018-01-08

    Over the past decade, technological advancements have transformed the delivery of care for arrhythmia patients. From early transtelephonic monitoring to new devices capable of wireless and cellular transmission, remote monitoring has revolutionized device care. In this article, we review the current evolution and evidence for remote monitoring in patients with cardiac implantable electronic devices. From passive transmission of device diagnostics, to active transmission of patient- and device-triggered alerts, remote monitoring can shorten the time to diagnosis and treatment. Studies have shown that remote monitoring can reduce hospitalization and emergency room visits, and improve survival. Remote monitoring can also reduce the health care costs, while providing increased access to patients living in rural or marginalized communities. Unfortunately, as many as two-thirds of patients with remote monitoring-capable devices do not use, or are not offered, this feature. Current guidelines recommend remote monitoring and interrogation, combined with annual in-person evaluation in all cardiac device patients. Remote monitoring should be considered in all eligible device patients and should be considered standard of care. Copyright © 2018 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  19. Conceptual problems with remote element synthesis

    Indian Academy of Sciences (India)

    The notion of remote element synthesis has recently been modified to explain the presence of nucleogenetic isotopic anomalies and decay products of short-lived nuclides by injection of a small amount of exotic nucleogenetic material. Even with this modification, remote element synthesis seems inconsistent with the ...

  20. Web Based Remote Access Microcontroller Laboratory

    OpenAIRE

    H. Çimen; İ. Yabanova; M. Nartkaya; S. M. Çinar

    2008-01-01

    This paper presents a web based remote access microcontroller laboratory. Because of accelerated development in electronics and computer technologies, microcontroller-based devices and appliances are found in all aspects of our daily life. Before the implementation of remote access microcontroller laboratory an experiment set is developed by teaching staff for training microcontrollers. Requirement of technical teaching and industrial applications are considered when expe...

  1. An Investigation of Information Technology-Enabled Remote Management and Remote Work Issues

    Directory of Open Access Journals (Sweden)

    D. Sandy Staples

    1997-05-01

    Full Text Available A two phase research study was done to investigate remote work and remote management issues. In Phase 1, focus groups were carried out with remote managers and remote employees to identify key issues. The most common key issues dealt with communications, information technology, leadership and coaching, teamwork, building trust, and performance management. In the second phase, a questionnaire was used to test hypotheses developed from phase 1. The findings supported that higher trust leads to higher job satisfaction and lower job stress, and that more communication between the manager and the remote employee develops higher levels of employee organizational commitment.

  2. Remote access to mathematical software

    International Nuclear Information System (INIS)

    Dolan, E.; Hovland, P.; More, J.; Norris, B.; Smith, B.

    2001-01-01

    The network-oriented application services paradigm is becoming increasingly common for scientific computing. The popularity of this approach can be attributed to the numerous advantages to both user and developer provided by network-enabled mathematical software. The burden of installing and maintaining complex systems is lifted from the user, while enabling developers to provide frequent updates without disrupting service. Access to software with similar functionality can be unified under the same interface. Remote servers can utilize potentially more powerful computing resources than may be available locally. We discuss some of the application services developed by the Mathematics and Computer Science Division at Argonne National Laboratory, including the Network Enabled Optimization System (NEOS) Server and the Automatic Differentiation of C (ADIC) Server, as well as preliminary work on Web access to the Portable Extensible Toolkit for Scientific Computing (PETSc). We also provide a brief survey of related work

  3. Remote sensing of the biosphere

    Science.gov (United States)

    1986-01-01

    The current state of understanding of the biosphere is reviewed, the major scientific issues to be addressed are discussed, and techniques, existing and in need of development, for the science are evaluated. It is primarily concerned with developing the scientific capabilities of remote sensing for advancing the subject. The global nature of the scientific objectives requires the use of space-based techniques. The capability to look at the Earth as a whole was developed only recently. The space program has provided the technology to study the entire Earth from artificial satellites, and thus is a primary force in approaches to planetary biology. Space technology has also permitted comparative studies of planetary atmospheres and surfaces. These studies coupled with the growing awareness of the effects that life has on the entire Earth, are opening new lines of inquiry in science.

  4. Lunar remote sensing and measurements

    Science.gov (United States)

    Moore, H.J.; Boyce, J.M.; Schaber, G.G.; Scott, D.H.

    1980-01-01

    Remote sensing and measurements of the Moon from Apollo orbiting spacecraft and Earth form a basis for extrapolation of Apollo surface data to regions of the Moon where manned and unmanned spacecraft have not been and may be used to discover target regions for future lunar exploration which will produce the highest scientific yields. Orbital remote sensing and measurements discussed include (1) relative ages and inferred absolute ages, (2) gravity, (3) magnetism, (4) chemical composition, and (5) reflection of radar waves (bistatic). Earth-based remote sensing and measurements discussed include (1) reflection of sunlight, (2) reflection and scattering of radar waves, and (3) infrared eclipse temperatures. Photographs from the Apollo missions, Lunar Orbiters, and other sources provide a fundamental source of data on the geology and topography of the Moon and a basis for comparing, correlating, and testing the remote sensing and measurements. Relative ages obtained from crater statistics and then empirically correlated with absolute ages indicate that significant lunar volcanism continued to 2.5 b.y. (billion years) ago-some 600 m.y. (million years) after the youngest volcanic rocks sampled by Apollo-and that intensive bombardment of the Moon occurred in the interval of 3.84 to 3.9 b.y. ago. Estimated fluxes of crater-producing objects during the last 50 m.y. agree fairly well with fluxes measured by the Apollo passive seismic stations. Gravity measurements obtained by observing orbiting spacecraft reveal that mare basins have mass concentrations and that the volume of material ejected from the Orientale basin is near 2 to 5 million km 3 depending on whether there has or has not been isostatic compensation, little or none of which has occurred since 3.84 b.y. ago. Isostatic compensation may have occurred in some of the old large lunar basins, but more data are needed to prove it. Steady fields of remanent magnetism were detected by the Apollo 15 and 16 subsatellites

  5. The remote security station (RSS)

    International Nuclear Information System (INIS)

    Pletta, J.B.

    1991-01-01

    This paper reports that, as an outgrowth of research into physical security systems, Sandia is investigating robotic technologies for improving physical security performance and flexibility. Robotic systems have the potential to allow more effective utilization of security personnel, especially in scenarios where they might be exposed to harm. They also can supplement fixed site installations where sensors have failed or where transient assets are present. The Remote Security Station (RSS) program for the defense Nuclear Agency is developing a proof-of-principle robotic system which will be used to evaluate the role, and associated cost, of robotic technologies in exterior physical security systems. The RSS consists of three primary elements: a fixed but quickly moveable tripod with intrusion detection sensors and assessment camera; a mobile robotic platform with a functionally identical security module; and a control console which allows an operator to perform security functions and teleoperate the mobile platform

  6. Energy and remote sensing applications

    Science.gov (United States)

    Summers, R. A.; Smith, W. L.; Short, N. M.

    1978-01-01

    The nature of the U.S. energy problem is examined. Based upon the best available estimates, it appears that demand for OPEC oil will exceed OPEC productive capacity in the early to mid-eighties. The upward pressure on world oil prices resulting from this supply/demand gap could have serious international consequences, both financial and in terms of foreign policy implementation. National Energy Plan objectives in response to this situation are discussed. Major strategies for achieving these objectives include a conversion of industry and utilities from oil and gas to coal and other abundant fuels. Remote sensing from aircraft and spacecraft could make significant contributions to the solution of energy problems in a number of ways, related to exploration of energy-related resources, the efficiency and safety of exploitation procedures, power plant siting, environmental monitoring and assessment, and the transportation infrastructure.

  7. A remote-operating laser

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    A laser has been developed into an efficient tool for remote cutting of metal parts, that will be used for dismantling nuclear installations. The YAG-type laser was chosen because it allows the transfer of power through optical fibers instead of mirrors. The feasibility of the cutting of pipes (diameter: 40 mm,thickness: 3 mm) and 40 mm thick steel slates has been proven at a distance of 1 meter by using a continuous 4 kW-laser. 2 lasers have been coupled to allow the contact cutting of 60 mm thick slates (speed: 40 mm/mn) by using an equivalent power of 6 kW. A 100 mm thick slate has been cut by an equivalent power of 7 kW with a speed of 3 mm/mn. (A.C.)

  8. Temporary balloon occlusion as therapy for uncontrollable arterial hemorrhage in multiply injured patients; Temporaere Ballonokklusion als Therapie unkontrollierbarer arterieller Blutungen bei Polytraumapatienten

    Energy Technology Data Exchange (ETDEWEB)

    Rieger, J.; Linsenmaier, U.; Rock, C.; Pfeifer, K.J. [Abt. fuer Radiologie, Klinikum Innenstadt, Ludwig-Maximilian-Univ., Muenchen (Germany); Euler, E. [Chirurgische Klinik und Poliklinik, Klinikum Innenstadt, Ludwig-Maximilian-Univ., Muenchen (Germany)

    1999-01-01

    Purpose: Presentation of temporary balloon occlusion as an interventional radiological method for managing hemorrhage in multiply injured patients with uncontrollable loss of blood. Method: Temporary, non-selective arterial occlusion by introduction of a balloon catheter contralaterally to the source of bleeding has been performed since 1992 on 7 patients with multiple injuries, hemorrhagic shock requiring reanimation, and angiographic demonstration of an arterial hemorrhage in the supply region of the internal iliac artery with complex pelvic fracture. In each case a PTA balloon catheter was introduced transfemorally, non-selectively positioned proximal to the bleeding source, and left in place for 24-48 h under manometric control. Control angiographies were performed prior to catheter removal. Results: The bleeding was stopped immediately in all 7 patients. The hemodynamic stability made transport and thus further surgical management and/or a short-term treatment in the intensive-care station possible. Control angiographies confirmed that the bleeding had stopped in all patients. Conclusions: We recommend temporary balloon occlusion as a rapid and effective method for the management of bleeding in otherwise uncontrollable traumatic hemorrhages in the supply region of the internal iliac artery. (orig.) [Deutsch] Ziel: Vorstellung der temporaeren Ballonokklusion als interventionell-radiologischer Methode zur Blutungskontrolle bei Polytraumapatienten mit unkontrollierbarem Blutverlust. Methode: Temporaerer, nicht-selektiver arterieller Gefaessverschluss mit kontralateral der Blutungsquellen eingefuehrten PTA-Ballonkathetern bei seit 1992 insgesamt 7 Patienten mit Polytrauma, reanimationspflichtigem haemorrhagischem Schock und angiographischem Nachweis einer arteriellen Blutung im Versorgungsgebiet der A. iliaca interna im Rahmen einer komplexen Beckenfraktur. Transfemoral wurde jeweils ein PTA-Ballonkatheter eingefuehrt, nicht selektiv proximal der Blutungsquelle

  9. Remote Sensing of Ocean Color

    Science.gov (United States)

    Dierssen, Heidi M.; Randolph, Kaylan

    The oceans cover over 70% of the earth's surface and the life inhabiting the oceans play an important role in shaping the earth's climate. Phytoplankton, the microscopic organisms in the surface ocean, are responsible for half of the photosynthesis on the planet. These organisms at the base of the food web take up light and carbon dioxide and fix carbon into biological structures releasing oxygen. Estimating the amount of microscopic phytoplankton and their associated primary productivity over the vast expanses of the ocean is extremely challenging from ships. However, as phytoplankton take up light for photosynthesis, they change the color of the surface ocean from blue to green. Such shifts in ocean color can be measured from sensors placed high above the sea on satellites or aircraft and is called "ocean color remote sensing." In open ocean waters, the ocean color is predominantly driven by the phytoplankton concentration and ocean color remote sensing has been used to estimate the amount of chlorophyll a, the primary light-absorbing pigment in all phytoplankton. For the last few decades, satellite data have been used to estimate large-scale patterns of chlorophyll and to model primary productivity across the global ocean from daily to interannual timescales. Such global estimates of chlorophyll and primary productivity have been integrated into climate models and illustrate the important feedbacks between ocean life and global climate processes. In coastal and estuarine systems, ocean color is significantly influenced by other light-absorbing and light-scattering components besides phytoplankton. New approaches have been developed to evaluate the ocean color in relationship to colored dissolved organic matter, suspended sediments, and even to characterize the bathymetry and composition of the seafloor in optically shallow waters. Ocean color measurements are increasingly being used for environmental monitoring of harmful algal blooms, critical coastal habitats

  10. Remote Whispering Applying Time Reversal

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Brian Eric [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-07-16

    The purpose of this project was to explore the use of time reversal technologies as a means for communication to a targeted individual or location. The idea is to have the privacy of whispering in one’s ear, but to do this remotely from loudspeakers not located near the target. Applications of this work include communicating with hostages and survivors in rescue operations, communicating imaging and operational conditions in deep drilling operations, monitoring storage of spent nuclear fuel in storage casks without wires, or clandestine activities requiring signaling between specific points. This technology provides a solution in any application where wires and radio communications are not possible or not desired. It also may be configured to self calibrate on a regular basis to adjust for changing conditions. These communications allow two people to converse with one another in real time, converse in an inaudible frequency range or medium (i.e. using ultrasonic frequencies and/or sending vibrations through a structure), or send information for a system to interpret (even allowing remote control of a system using sound). The time reversal process allows one to focus energy to a specific location in space and to send a clean transmission of a selected signal only to that location. In order for the time reversal process to work, a calibration signal must be obtained. This signal may be obtained experimentally using an impulsive sound, a known chirp signal, or other known signals. It may also be determined from a numerical model of a known environment in which the focusing is desired or from passive listening over time to ambient noise.

  11. Remote Arrhythmia Monitoring System Developed

    Science.gov (United States)

    York, David W.; Mackin, Michael A.; Liszka, Kathy J.; Lichter, Michael J.

    2004-01-01

    Telemedicine is taking a step forward with the efforts of team members from the NASA Glenn Research Center, the MetroHealth campus of Case Western University, and the University of Akron. The Arrhythmia Monitoring System is a completed, working test bed developed at Glenn that collects real-time electrocardiogram (ECG) signals from a mobile or homebound patient, combines these signals with global positioning system (GPS) location data, and transmits them to a remote station for display and monitoring. Approximately 300,000 Americans die every year from sudden heart attacks, which are arrhythmia cases. However, not all patients identified at risk for arrhythmias can be monitored continuously because of technological and economical limitations. Such patients, who are at moderate risk of arrhythmias, would benefit from technology that would permit long-term continuous monitoring of electrical cardiac rhythms outside the hospital environment. Embedded Web Technology developed at Glenn to remotely command and collect data from embedded systems using Web technology is the catalyst for this new telemetry system (ref. 1). In the end-to-end system architecture, ECG signals are collected from a patient using an event recorder and are transmitted to a handheld personal digital assistant (PDA) using Bluetooth, a short-range wireless technology. The PDA concurrently tracks the patient's location via a connection to a GPS receiver. A long distance link is established via a standard Internet connection over a 2.5-generation Global System for Mobile Communications/General Packet Radio Service (GSM/GPRS)1 cellular, wireless infrastructure. Then, the digital signal is transmitted to a call center for monitoring by medical professionals.

  12. The mysteries of remote memory

    Science.gov (United States)

    2018-01-01

    Long-lasting memories form the basis of our identity as individuals and lie central in shaping future behaviours that guide survival. Surprisingly, however, our current knowledge of how such memories are stored in the brain and retrieved, as well as the dynamics of the circuits involved, remains scarce despite seminal technical and experimental breakthroughs in recent years. Traditionally, it has been proposed that, over time, information initially learnt in the hippocampus is stored in distributed cortical networks. This process—the standard theory of memory consolidation—would stabilize the newly encoded information into a lasting memory, become independent of the hippocampus, and remain essentially unmodifiable throughout the lifetime of the individual. In recent years, several pieces of evidence have started to challenge this view and indicate that long-lasting memories might already ab ovo be encoded, and subsequently stored in distributed cortical networks, akin to the multiple trace theory of memory consolidation. In this review, we summarize these recent findings and attempt to identify the biologically plausible mechanisms based on which a contextual memory becomes remote by integrating different levels of analysis: from neural circuits to cell ensembles across synaptic remodelling and epigenetic modifications. From these studies, remote memory formation and maintenance appear to occur through a multi-trace, dynamic and integrative cellular process ranging from the synapse to the nucleus, and represent an exciting field of research primed to change quickly as new experimental evidence emerges. This article is part of a discussion meeting issue ‘Of mice and mental health: facilitating dialogue between basic and clinical neuroscientists’. PMID:29352028

  13. Remote sensing of wetlands applications and advances

    CERN Document Server

    Tiner, Ralph W; Klemas, Victor V

    2015-01-01

    Effectively Manage Wetland Resources Using the Best Available Remote Sensing Techniques Utilizing top scientists in the wetland classification and mapping field, Remote Sensing of Wetlands: Applications and Advances covers the rapidly changing landscape of wetlands and describes the latest advances in remote sensing that have taken place over the past 30 years for use in mapping wetlands. Factoring in the impact of climate change, as well as a growing demand on wetlands for agriculture, aquaculture, forestry, and development, this text considers the challenges that wetlands pose for remote sensing and provides a thorough introduction on the use of remotely sensed data for wetland detection. Taking advantage of the experiences of more than 50 contributing authors, the book describes a variety of techniques for mapping and classifying wetlands in a multitude of environments ranging from tropical to arctic wetlands including coral reefs and submerged aquatic vegetation. The authors discuss the advantages and di...

  14. Best practices in Remote Sensing for REDD+

    DEFF Research Database (Denmark)

    Dons, Klaus; Grogan, Kenneth

    2012-01-01

    due to steep terrain, • phenological gradients across natural, agricultural and forestry ecosystems including plantations and • the need to serve the REDD-specific context of deforestation and forest degradation across spatial and temporal scales make remote sensing based approaches particularly...... be expected from remote sensing imagery and the provided information shall help to better anticipate problems that will be encountered when acquiring, analyzing and interpreting remote sensing data. Beyond remote sensing, it may be a good point of departure for a large group of scientists with a diverse...... and governance, and deforestation and forest degradation processes. The second part summarizes the available literature on remote sensing based good practices for REDD. It largely draws from the documents of the Intergovernmental Panel on Climate Change (IPCC), the United Nations Framework Convention on Climate...

  15. Remote data acquisition system based on MSM7512B8

    International Nuclear Information System (INIS)

    Jiang Junfeng

    2003-01-01

    This paper introduces a remote data acquisition system based on MC68HC908GP32 and MSM7512B, which can accomplish remote data communications on telephone network, and realize remote data acquisition. (authors)

  16. The effects of a novel psychological attribution and emotional awareness and expression therapy for chronic musculoskeletal pain: A preliminary, uncontrolled trial.

    Science.gov (United States)

    Burger, Amanda J; Lumley, Mark A; Carty, Jennifer N; Latsch, Deborah V; Thakur, Elyse R; Hyde-Nolan, Maren E; Hijazi, Alaa M; Schubiner, Howard

    2016-02-01

    Current psychological and behavioral therapies for chronic musculoskeletal pain only modestly reduce pain, disability, and distress. These limited effects may be due to the failure of current therapies: a) to help patients learn that their pain is influenced primarily by central nervous system psychological processes; and b) to enhance awareness and expression of emotions related to psychological trauma or conflict. We developed and conducted a preliminary, uncontrolled test of a novel psychological attribution and emotional awareness and expression therapy that involves an initial individual consultation followed by 4 group sessions. A series of 72 patients with chronic musculoskeletal pain had the intervention and were assessed at baseline, post-treatment, and 6-month follow-up. Participation and satisfaction were high and attrition was low. Intent-to-treat analyses found significant improvements in hypothesized change processes: psychological attributions for pain, emotional awareness, emotional approach coping, and alexithymia. Pain, interference, depression, and distress showed large effect size improvements at post-treatment, which were maintained or even enhanced at 6 months. Approximately two-thirds of the patients improved at least 30% in pain and other outcomes, and one-third of the patients improved 70%. Changes in attribution and emotional processes predicted outcomes. Higher baseline depressive symptoms predicted greater improvements, and outcomes were comparable for patients with widespread vs. localized pain. This novel intervention may lead to greater benefits than available psychological interventions for patients with chronic musculoskeletal pain, but needs controlled testing. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. The development of the American National Standard 'control of radioactive surface contamination on materials equipment and facilities to be released for uncontrolled use'

    International Nuclear Information System (INIS)

    Shapiro, J.

    1980-01-01

    A new standard submitted by the Health Physics Society Standards Committee to the American National Standards Institute concerning radioactive surface contamination of materials and equipment is discussed. The chronological events in the development of this standard are given. The standard provides criteria for the release for uncontrolled use of materials, equipment and facilities contaminated or potentially contaminated with radioactivity. Permissible contamination limits are specified for: 1) long lived alpha emitters except natural uranium and thorium, 2) more hazardous beta-gamma emitters, 3) less hazardous beta-gamma emitters and 4) natural uranium and thorium. A contamination reference level of 1000 dpm/100 cm 2 for 90 Sr was set as the basis for assigning limits to radionuclides presenting an ingestion hazard and other radionuclides were grouped based on the values of their maximum permissible concentration (MPC) in water relative to 90 Sr. The contamination limit for 239 Pu was chosen as the basis for assigning limits based on MPC in air to radionuclides presenting an inhalation hazard; a value of 100 dpm/100 cm 2 was adopted in the standard. An upper limit of 5000 dpm/100 cm 2 for surface contamination was selected for the standard. (UK)

  18. Clinical and metabolic evaluation of one-stage, full-mouth, ultrasonic debridement as a therapeutic approach for uncontrolled type 2 diabetic patients with periodontitis.

    Science.gov (United States)

    Cirano, Fabiano Ribeiro; Pera, Claudia; Ueda, Paulo; Casarin, Renato Correa Viana; Ribeiro, Fernanda Vieira; Pimentel, Suzana Peres; Casati, Marcio Zaffalon

    2012-09-01

    To evaluate the therapeutic potential of one-stage, full-mouth, ultrasonic debridement (FMUD) as a treatment for type 2 diabetic patients with generalized severe chronic periodontitis. Sixteen patients diagnosed with generalized severe chronic periodontitis and type 2 diabetes mellitus were allocated to the diabetic group; another 15 subjects with periodontitis but without metabolic disorders were placed in the nondiabetic group. Both groups were treated using the FMUD protocol, a unique 45-minute session of ultrasonic debridement of all sites presenting periodontal disease. Patients were analyzed for the following parameters: plaque and bleeding indices, gingival recession, probing depth, and clinical attachment level. Further, diabetic subjects were assessed using fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) tests. Patients were evaluated at 3 and 6 months for all parameters. ANOVA and the Tukey test were used for data analysis (P periodontal health after treatment. There were no significant differences between the groups for any of the parameters assessed (P > .05). Diabetic subjects treated with FMUD had a clinical response similar to that of nondiabetic subjects at all pocket depths. No adverse effects or medical disturbances were observed in either group during treatment. FPG and HbA1c levels remained unaltered after treatment. Within the limitations of this study, FMUD promoted clinical improvements in patients with type 2 uncontrolled diabetes and generalized severe chronic periodontitis.

  19. An Open-Label Uncontrolled, Multicenter Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess VOLUME in the Treatment of Nasolabial Folds

    Directory of Open Access Journals (Sweden)

    Daisy Kopera

    2015-01-01

    Full Text Available The dermal filler Princess VOLUME is a highly cross-linked, viscoelastic hyaluronic acid injectable gel implant used for aesthetic treatment. To evaluate the efficacy and safety of Princess VOLUME in the treatment of nasolabial folds, an open-label uncontrolled, multicenter study was conducted. Forty-eight subjects were recruited who had moderate to deep wrinkles, according to the Modified Fitzpatrick Wrinkle Scale (MFWS. Subjects received Princess VOLUME in both nasolabial folds at Day 0. Nasolabial fold severity was evaluated at 30, 90, 180, and 270 days after treatment, using the MFWS and the Global Aesthetic Improvement Scale (GAIS. Adverse events and treatment site reactions were recorded. Among the 48 subjects, 93.8% were female with a median age of 52 years. There were significant improvements (P<0.0001 in the MFWS scores at 30, 180, and 270 days after treatment compared with those at baseline, with a mean decrease of 1.484 (±0.408, 1.309 (±0.373, and 1.223 (±0.401, respectively; hence the primary endpoint was achieved and clinical efficacy demonstrated. Princess VOLUME was well tolerated, and most adverse events were injection site reactions of mild to moderate severity. Subject satisfaction (97.9%, subject recommendation of the treatment (93.6%, and investigators GAIS scores (97.9% improvement were high.

  20. Uncontrolled diabetes mellitus: prevalence and risk factors among people with type 2 diabetes mellitus in an Urban District of Karachi, Pakistan.

    Science.gov (United States)

    Siddiqui, Fahad Javaid; Avan, Bilal Iqbal; Mahmud, Sadia; Nanan, Debra J; Jabbar, Abdul; Assam, Pryseley Nkouibert

    2015-01-01

    This study aimed to explore the prevalence of, and factors associated with, uncontrolled diabetes mellitus (UDM) in a community setting in Pakistan. A single-center, cross-sectional study, conducted in a community-based specialized care center (SCC) for diabetes in District Central Karachi, in 2003, registered 452 type 2 DM participants, tested for HbA1c and interviewed face-to-face for other information. Logistic regression analysis was conducted to identify factors associated with UDM. Prevalence of UDM among diabetes patients was found to be 38.9% (95% CI: 34.4-43.4%). Multivariable logistic regression model analysis indicated that age diabetes information from a doctor or nurse only (vs. multiple sources) (OR: 1.8; 95% CI: 1.2-2.9), higher monthly treatment cost (OR: 1.3; 95% CI: 1.1-1.6; for every extra 500 PKR), and higher consumption of tea (OR: 1.5; 95% CI: 1.0-2.2; for every 2 extra cups) were independently associated with UDM. The prevalence of UDM was approximately 39% among persons with type 2 diabetes visiting a community based SCC for diabetes. Modifiable risk factors such as sources of diabetes information and black tea consumption can be considered as potential targets of interventions in Karachi. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  1. Huge bilateral ovarian cysts in adulthood as the presenting feature of Van Wyk Grumbach syndrome due to chronic uncontrolled juvenile hypothyroidism

    Directory of Open Access Journals (Sweden)

    K S Shivaprasad

    2013-01-01

    Full Text Available Juvenile primary hypothyroidism causing cystic ovaries and pseudoprecocious puberty (Van-Wyk Grumbach syndrome (VWGS is well documented in literature. There are only a few reports of primary hypothyroidism presenting as ovarian cysts in adults. Here we present a case of huge bilateral ovarian cysts in adulthood as the presenting feature of VWGS due to chronic uncontrolled juvenile hypothyroidism. Large uniloculor right ovarian cyst (119 × 81 × 90 mm and a multicystic left ovary (55 × 45 × 49 mm were detected in a 24 year lady with secondary amenorrhea, galactorrhea, and palpable abdominal mass with history of neonatal jaundice, delayed milestones, short stature, and precocious menarche at age of 7.5 years age. She had elevated levels of cancer antigen (CA-125 which normalized post levothyroxine supplementation. Elevated CA-125 may lead to misdiagnosis of ovarian carcinoma and inadvertent treatment. Bilateral ovarian cysts in adults are a rare presentation of juvenile hypothyroidism. It is necessary to screen for primary hypothyroidism in patients presenting with bilateral ovarian cysts to prevent unnecessary evaluation and treatment.

  2. Outcome of physiotherapy as part of a multidisciplinary rehabilitation in an unselected polio population with one-year follow-up: an uncontrolled study.

    Science.gov (United States)

    Bertelsen, Merete; Broberg, Susse; Madsen, Ellen

    2009-01-01

    The aim of this study was to evaluate the outcome of physiotherapy as part of a multidisciplinary rehabilitation. Prospective uncontrolled intervention study. Fifty patients with late effects of polio, first time referred to physiotherapy at the Danish Society of Polio and Accident Victims (PTU) Rehabilitation Centre. The intervention was physiotherapy as an essential part of an individually planned multidisciplinary rehabilitation. The outcome measures Six-Minute Walk Test and Timed-Stands Test were used to assess the functional capacity. Quality of life was evaluated by Medical Outcome Survey Short Form (SF-36) and fatigue by Multidimensional Fatigue Inventory (MFI-20). Patients were tested at baseline; 3 months after the start of rehabilitation and at one-year follow-up. The patients showed significantly better functional capacity on all measurements 3 months after start of intervention and at one-year follow-up. The patients showed significant improvement in 3 of the SF-36 dimensions regarding quality of life, but only the improvement in "general health" remained after one year. This study shows that patients with late effects of polio, who experience new problems related to polio, can benefit from an individually planned multidisciplinary intervention with emphasis on physiotherapy, and the improvement in physical capacity and general health can remain at one-year follow-up.

  3. Impact of NGO training and support intervention on diarrhoea management practices in a rural community of Bangladesh: an uncontrolled, single-arm trial.

    Science.gov (United States)

    Rahman, Ahmed S; Islam, Mohammad Rafiqul; Koehlmoos, Tracey P; Raihan, Mohammad Jyoti; Hasan, Mohammad Mehedi; Ahmed, Tahmeed; Larson, Charles P

    2014-01-01

    The evolving Non-Governmental Organization (NGO) sector in Bangladesh provides health services directly, however some NGOs indirectly provide services by working with unlicensed providers. The primary objective of this study was to examine the impact of NGO training of unlicensed providers on diarrhoea management and the scale up of zinc treatment in rural populations. An uncontrolled, single-arm trial for a training and support intervention on diarrhoea outcomes was employed in a rural sub-district of Bangladesh during 2008. Two local NGOs and their catchment populations were chosen for the study. The intervention included training of unlicensed health care providers in the management of acute childhood diarrhoea, particularly emphasizing zinc treatment. In addition, community-based promotion of zinc treatment was carried out. Baseline and endline ecologic surveys were carried out in intervention and control villages to document changes in treatments received for diarrhoea in under-five children. Among surveyed household with an active or recent acute childhood diarrhoea episode, 69% sought help from a health provider. Among these, 62.8% visited an unlicensed private provider. At baseline, 23.9% vs. 22% of control and intervention group children with diarrhoea had received zinc of any type. At endline (6 months later) this had changed to 15.3% vs. 30.2%, respectively. The change in zinc coverage was significantly higher in the intervention villages (pmanagement of under-five children in rural Bangladesh households. ClinicalTrials.gov NCT02143921.

  4. A Complex Multiherbal Regimen Based on Ayurveda Medicine for the Management of Hepatic Cirrhosis Complicated by Ascites: Nonrandomized, Uncontrolled, Single Group, Open-Label Observational Clinical Study.

    Science.gov (United States)

    Patel, Manish V; Patel, Kalapi B; Gupta, Shivenarain; Michalsen, Andreas; Stapelfeldt, Elmar; Kessler, Christian S

    2015-01-01

    Hepatic cirrhosis is one of the leading causes of death worldwide, especially if complicated by ascites. This chronic condition can be related to the classical disease entity jalodara in Traditional Indian Medicine (Ayurveda). The present paper aims to evaluate the general potential of Ayurvedic therapy for overall clinical outcomes in hepatic cirrhosis complicated by ascites (HCcA). In form of a nonrandomized, uncontrolled, single group, open-label observational clinical study, 56 patients fulfilling standardized diagnostic criteria for HCcA were observed during their treatment at the P. D. Patel Ayurveda Hospital, Nadiad, India. Based on Ayurvedic tradition, a standardized treatment protocol was developed and implemented, consisting of oral administration of single and compound herbal preparations combined with purificatory measures as well as dietary and lifestyle regimens. The outcomes were assessed by measuring liver functions through specific clinical features and laboratory parameters and by evaluating the Child-Pugh prognostic grade score. After 6 weeks of treatment and a follow-up period of 18 weeks, the outcomes showed statistically significant and clinically relevant improvements. Further larger and randomized trials on effectiveness, safety, and quality of the Ayurvedic approach in the treatment of HCcA are warranted to support these preliminary findings.

  5. Practical remote monitoring using COTS equipment

    International Nuclear Information System (INIS)

    Kadner, S.; White, R.M.; Pepper, S.

    1999-01-01

    It has been clear for some time that the gap between the international nonproliferation verification agenda and the available financial means can only be bridged by adoption of remote monitoring technologies in specific safeguards applications. Past technology development efforts have focused largely on sensor networking and dedicated communications services to link the inspector to the Safeguards instruments using the traditional verification paradigm. Today we have several Commercial Off The Shelf (COTS) sensor networking alternatives that are viable for Safeguards and it has been found that no single communication service can be uniformly deployed in all verification scenarios. While sensor networking is an important element of remote monitoring technology, it does not by itself provide a viable remote monitoring capability. This paper discusses several lessons have been learned from the IAEA's remote monitoring installation in Pelindaba, South Africa and how those lessons have been extended to near-term installations in Japan and Canada. Key among those lessons is that the traditional verification paradigm cannot, and should not, be carried forward into the remote monitoring regime and that the primary technology component of the successful remote monitoring installation is the Server, which processes, filters, categorizes, and otherwise acts on the sensor inputs to dramatically reduce the volume and increase the information -density of data that is transferred remotely using indigenous communication infrastructures. (author)

  6. Progress on ITER remote experimentation centre

    Energy Technology Data Exchange (ETDEWEB)

    Ozeki, Takahisa, E-mail: ozeki.takahisa@jaea.go.jp [Japan Atomic Energy Agency, 2-166 Obuchi Rokkasho, Kitakami-gun, Aomori 039-3212 (Japan); Clement-Lorenzo, Susana [Fusion for Energy, Torres Diagonal Litoral, B3, 13/03, Barcelona 08019 (Spain); Nakajima, Noriyoshi [National institute for Fusion Science and Project leader of IFERC, 2-166 Obuchi, Rokkasho, Kamikita-gun, Aomori 039-3212 (Japan)

    2016-11-15

    Construction of ITER remote experimentation centre (REC) based on the broader approach (BA) activity of the joint program of Japan and Europe (EU) is progressing. In order to make the future experiments of ITER and JT-60SA effectively and efficiently implemented, development of a remote experiment system by using the Satellite Tokamak (JT-60SA) facilities was planned and the development of software for the remote experiment is ongoing, including the systems for the remote connection and the communication between the remote site and the on-site facility. The network system from REC in Rokkasho-site of Japan to the network in EU was established in collaboration with the National Institute of Informatics (NII). Effective data transfer method that is capable of fast transfer speeds in the gigabit range is investigated. Data transfer at the rate of several Gbps was successfully obtained between the institutes in Japan. The preliminary versions of the software for data analysis are developed, such as for visualization of time dependent experimental data and transport simulations, visualization of plasma boundary/equilibrium and spatial profiles of diagnostic data. The remote data access program and an integrated platform for Documentation and Experiment Management are also being developed. A remote experiment room in the Rokkasho-site in Japan was designed and the construction started. The function of REC will be tested and the total system will be demonstrated by the middle of 2017.

  7. Progress on ITER remote experimentation centre

    International Nuclear Information System (INIS)

    Ozeki, Takahisa; Clement-Lorenzo, Susana; Nakajima, Noriyoshi

    2016-01-01

    Construction of ITER remote experimentation centre (REC) based on the broader approach (BA) activity of the joint program of Japan and Europe (EU) is progressing. In order to make the future experiments of ITER and JT-60SA effectively and efficiently implemented, development of a remote experiment system by using the Satellite Tokamak (JT-60SA) facilities was planned and the development of software for the remote experiment is ongoing, including the systems for the remote connection and the communication between the remote site and the on-site facility. The network system from REC in Rokkasho-site of Japan to the network in EU was established in collaboration with the National Institute of Informatics (NII). Effective data transfer method that is capable of fast transfer speeds in the gigabit range is investigated. Data transfer at the rate of several Gbps was successfully obtained between the institutes in Japan. The preliminary versions of the software for data analysis are developed, such as for visualization of time dependent experimental data and transport simulations, visualization of plasma boundary/equilibrium and spatial profiles of diagnostic data. The remote data access program and an integrated platform for Documentation and Experiment Management are also being developed. A remote experiment room in the Rokkasho-site in Japan was designed and the construction started. The function of REC will be tested and the total system will be demonstrated by the middle of 2017.

  8. Hot Laboratories and Remote Handling

    International Nuclear Information System (INIS)

    2007-01-01

    The Opening talk of the workshop 'Hot Laboratories and Remote Handling' was given by Marin Ciocanescu with the communication 'Overview of R and D Program in Romanian Institute for Nuclear Research'. The works of the meeting were structured into three sections addressing the following items: Session 1. Hot cell facilities: Infrastructure, Refurbishment, Decommissioning; Session 2. Waste, transport, safety and remote handling issues; Session 3. Post-Irradiation examination techniques. In the frame of Section 1 the communication 'Overview of hot cell facilities in South Africa' by Wouter Klopper, Willie van Greunen et al, was presented. In the framework of the second session there were given the following four communications: 'The irradiated elements cell at PHENIX' by Laurent Breton et al., 'Development of remote equipment for DUPIC fuel fabrication at KAERI', by Jung Won Lee et al., 'Aspects of working with manipulators and small samples in an αβγ-box, by Robert Zubler et al., and 'The GIOCONDA experience of the Joint Research Centre Ispra: analysis of the experimental assemblies finalized to their safe recovery and dismantling', by Roberto Covini. Finally, in the framework of the third section the following five communications were presented: 'PIE of a CANDU fuel element irradiated for a load following test in the INR TRIGA reactor' by Marcel Parvan et al., 'Adaptation of the pole figure measurement to the irradiated items from zirconium alloys' by Yury Goncharenko et al., 'Fuel rod profilometry with a laser scan micrometer' by Daniel Kuster et al., 'Raman spectroscopy, a new facility at LECI laboratory to investigate neutron damage in irradiated materials' by Lionel Gosmain et al., and 'Analysis of complex nuclear materials with the PSI shielded analytical instruments' by Didier Gavillet. In addition, eleven more presentations were given as posters. Their titles were: 'Presentation of CETAMA activities (CEA analytic group)' by Alain Hanssens et al. 'Analysis of

  9. The ITER Remote Maintenance Management System

    International Nuclear Information System (INIS)

    Tesini, Alessandro; Rolfe, A.C.

    2009-01-01

    A major challenge for the ITER project is to develop and implement a Remote Maintenance System, which can deliver high Tokamak availability within the constraints of the overall ITER programme objectives. Much of the maintenance of ITER will be performed using remote handling methods and some with combined manual and remote activities working together. The organization and management of the ITER remote handling facilities will be of a scale unlike any other remote handling application in the world. The ITER remote handling design and procurement activities will require co-ordination and management across many different sites throughout the world. It will be a major challenge for the ITER project to ensure a consistent quality and technical approach in all of the contributing parties. To address this issue the IO remote handling team are implementing the ITER Maintenance Management Plan (IMMP) comprising an overarching document defining the policies and methodologies (ITER Remote Maintenance Management System or IMMS) and an associated ITER remote handling code of practise (IRHCOP). The IMMS will be in document form available as a pdf file or similar. The IRHCOP will be implemented as a web based application and will provide access to the central resource of the entire code of practise from any location in the world. The IRHCOP data library will be centrally controlled in order that users can be assured of the data relevance and authenticity. This paper will describe the overall approach being taken to deal with this challenge and go on to detail the structure and content of both the IMMS and the IRHCOP.

  10. Web Development Techniques and Remote Laboratories

    Directory of Open Access Journals (Sweden)

    Doru Ursutiu

    2009-08-01

    Full Text Available In the actual context of the world economic and financial crisis, any source that causes economy is welcomed. In the technical educational system such a source is represented by the implementation of remote labs. These allow, among other things, the sharing of modern technology between several centers and also the saving of power by using an adequate energetic management. This paper presents a solution for implementing remote labs by using web technologies that are platform independent from the client point of view. Such a lab implementation exemplification is materialized by remote controlling the NI-ELVIS platform.

  11. Preface: Remote Sensing in Coastal Environments

    Directory of Open Access Journals (Sweden)

    Deepak R. Mishra

    2016-08-01

    Full Text Available The Special Issue (SI on “Remote Sensing in Coastal Environments” presents a wide range of articles focusing on a variety of remote sensing models and techniques to address coastal issues and processes ranging for wetlands and water quality to coral reefs and kelp habitats. The SI is comprised of twenty-one papers, covering a broad range of research topics that employ remote sensing imagery, models, and techniques to monitor water quality, vegetation, habitat suitability, and geomorphology in the coastal zone. This preface provides a brief summary of each article published in the SI.

  12. Remote process connectors for the NWCF

    International Nuclear Information System (INIS)

    Jacobs, R.T.; Carter, J.A.; Hohback, A.C.

    1978-01-01

    The remote process connectors developed, used, and tested at the Remote Maintenance Development Facility are described. These connectors, including the 3-bolt kinematic-graphite flange and watertight-electrical connectors, are assembled on master jigs (holding-welding fixture) to form interchangeable pump and valve loop assemblies. These assemblies, with their guide-in platforms make possible a method of performing remote maintenance at the New Waste Calcining Facility that is a departure from methods which until now have been the standard of the industry

  13. Facility operations transparency and remote monitoring

    International Nuclear Information System (INIS)

    Beddingfield, David

    2006-01-01

    Remote monitoring technologies offer many opportunities, not only to strengthen IAEA safeguards, but also to improve national, industrial and local oversight of various nuclear operations. Remote monitoring benefits in greater timeliness, reduced inspector presence and improved state-of-health awareness are well-known attributes. However, there is also the capability to organize data into a comprehensive knowledge of the 'normal operating envelope' of a facility. In considering future applications of remote monitoring there is also a need to develop a better understanding of the potential cost-savings versus higher up-front costs and potential long-term maintenance or upgrade costs. (author)

  14. Remote nuclear screening system for hostile environments

    International Nuclear Information System (INIS)

    Addleman, R.S.; Keele, B.D.

    1996-01-01

    A remote measurement system has been constructed for in situ gamma and beta isotopic characterization of highly radioactive nuclear material in hostile environments. A small collimated, planar CdZnTe detector is used for gamma-ray spectroscopy. Spectral resolution of 2% full width at half maximum at 662 kiloelectronvolts has been obtained remotely using rise time compensation and limited pulse shape discrimination, Isotopc measurement of high-energy beta emitters was accomplished with a ruggedized, deeply depleted, surface barrier silicon dictator. The primary function of the remote nuclear screening system is to provide fast qualitative and quantitative isotopic assessment of high-level radioactive material

  15. Improvements in remote equipment torquing and fastening

    International Nuclear Information System (INIS)

    Garin, J.

    1978-01-01

    Remote torquing and fastening is a requirement of generic interest for application in an environment not readily accessible to man. The developments over the last 30 years in torque-controlled equipment above 200 nm (150 ft/lb) have not been emphasized. The development of specialized subassemblies to torque and fasten equipment in a remotely controlled environment is an integral part of the Advanced Fuel Recycle Program at Oak Ridge National Laboratory. Commercially available subassemblies have been adapted into a system that would provide remote torquing and fastening in the range of 200 to 750 nm (150 to 550 ft/lb). 9 figures

  16. The TMI-2 remote technology program

    International Nuclear Information System (INIS)

    Bengel, P.R.

    1986-01-01

    Since the accident at Three Mile Island Unit 2 (TMI-2), an aggressive approach has been pursued in developing the tools needed for the recovery of the plant. The plant's owner has embarked on a systematic program to develop remote equipment. The program developed conceptual and then physical equipment. The remote reconnaissance vehicles (RRVs) and the remote working vehicle (RWV) span the requirements of the recovery program from the ability to perform radiological and video surveys to heavy-duty decontamination and demolition work. 4 figs

  17. Discriminative learning after uncontrollable shocks

    Directory of Open Access Journals (Sweden)

    Angelica Capelari

    2009-10-01

    Full Text Available O objetivo desse estudo foi investigar se estímulos aversivos não contingentes (incontroláveis produzem interferência em um processo de aprendizagem discriminativa reforçada positivamente. Vinte e quatro ratos foram distribuídos em três grupos (n=8 que diferiram entre si quanto ao tratamento recebido na primeira sessão: choques controláveis (C, incontroláveis (I ou nenhum choque (N. Posteriormente, todos foram submetidos a 10 sessões de treino discriminativo com reforço positivo, em esquema múltiplo-concorrente FR-6/Extinção. Os resultados do treino discriminativo mostraram que, na primeira sessão, a exposição prévia a choques produziu menor frequência de respostas, sendo esse efeito levemente mais acentuado no grupo I; na décima sessão, os grupos não diferiram entre si quanto à frequência de respostas e ao índice discriminativo, que ficou acima de 0,80. O efeito transitório do tratamento com choques incontroláveis, sem interferência a longo prazo no estabelecimento do controle de estímulos por reforçamento positivo, é contrário à generalidade do desamparo aprendido para contextos não aversivos.   Palavras-chave: desamparo aprendido; incontrolabilidade; controle de estímulos.

  18. Discriminative learning after uncontrollable shocks

    OpenAIRE

    Angelica Capelari; Maria Helena Leite Hunziker

    2009-01-01

    O objetivo desse estudo foi investigar se estímulos aversivos não contingentes (incontroláveis) produzem interferência em um processo de aprendizagem discriminativa reforçada positivamente. Vinte e quatro ratos foram distribuídos em três grupos (n=8) que diferiram entre si quanto ao tratamento recebido na primeira sessão: choques controláveis (C), incontroláveis (I) ou nenhum choque (N). Posteriormente, todos foram submetidos a 10 sessões de treino discriminativo com reforço positivo, em esqu...

  19. Uncontrolled transport of nuclear materials

    International Nuclear Information System (INIS)

    Wassermann, U.

    1985-01-01

    An account is given of international transport of plutonium, uranium oxides, uranium hexafluoride, enriched uranium and irradiated fuel for reprocessing. Referring to the sinking of the 'Mont Louis', it is stated that the International Maritime Organization has been asked by the National Union of Seamen and 'Greenpeace' to bar shipment of radioactive material until stricter international safety regulations are introduced. (U.K.)

  20. Polarization-based index of refraction and reflection angle estimation for remote sensing applications

    Science.gov (United States)

    Thilak, Vimal; Voelz, David G.; Creusere, Charles D.

    2007-10-01

    A passive-polarization-based imaging system records the polarization state of light reflected by objects that are illuminated with an unpolarized and generally uncontrolled source. Such systems can be useful in many remote sensing applications including target detection, object segmentation, and material classification. We present a method to jointly estimate the complex index of refraction and the reflection angle (reflected zenith angle) of a target from multiple measurements collected by a passive polarimeter. An expression for the degree of polarization is derived from the microfacet polarimetric bidirectional reflectance model for the case of scattering in the plane of incidence. Using this expression, we develop a nonlinear least-squares estimation algorithm for extracting an apparent index of refraction and the reflection angle from a set of polarization measurements collected from multiple source positions. Computer simulation results show that the estimation accuracy generally improves with an increasing number of source position measurements. Laboratory results indicate that the proposed method is effective for recovering the reflection angle and that the estimated index of refraction provides a feature vector that is robust to the reflection angle.