WorldWideScience

Sample records for solar spectroscopic imager

  1. Solar Flares and the High Energy Solar Spectroscopic Imager (HESSI)

    Holman, Gordon D.; Fisher, Richard R. (Technical Monitor)

    2001-01-01

    Solar flares are the biggest explosions in the solar system. They are important both for understanding explosive events in the Universe and for their impact on human technology and communications. The satellite-based HESSI is designed to study the explosive release of energy and the acceleration of electrons, protons, and other charged particles to high energies in solar flares. HESSI produces "color" movies of the Sun in high-energy X rays and gamma rays radiated by these energetic particles. HESSI's X-ray and gamma-ray images of flares are obtained using techniques similar to those used in radio interferometry. Ground-based radio observations of the Sun provide an important complement to the HESSI observations of solar flares. I will describe the HESSI Project and the high-energy aspects of solar flares, and how these relate to radio astronomy techniques and observations.

  2. High Energy Solar Spectroscopic Imager (HESSI) Team Investigations

    Emslie, A. Gordon

    1998-01-01

    This report covers activities on the above grant for the period through the end of September 1997. The work originally proposed to be performed under a three-year award was converted at that time to a two-year award for the remainder of the period, and is now funded under award NAGS-4027 through Goddard Space Flight Center. The P.I. is a co-investigator on the High Energy Solar Spectroscopic Imager (HESSI) team, selected as a Small-Class Explorer (SNMX) mission in 1997. He has also been a participant in the Space Physics Roadmap Planning Group. Our research has been strongly influenced by the NASA mission opportunities related to these activities. The report is subdivided into four sections, each dealing with a different aspect of our research within this guiding theme. Personnel involved in this research at UAH include the P.I. and graduate students Michele Montgomery and Amy Winebarger. Much of the work has been carried out in collaboration with investigators at other institutions, as detailed below. Attachment: Laser wakefield acceleration and astrophysical applications.

  3. Solar Flares Observed with the Ramaty High Energy Solar Spectroscopic Imager (RHESSI)

    Holman, Gordon D.

    2004-01-01

    Solar flares are impressive examples of explosive energy release in unconfined, magnetized plasma. It is generally believed that the flare energy is derived from the coronal magnetic field. However, we have not been able to establish the specific energy release mechanism(s) or the relative partitioning of the released energy between heating, particle acceleration (electrons and ions), and mass motions. NASA's RHESSI Mission was designed to study the acceleration and evolution of electrons and ions in flares by observing the X-ray and gamma-ray emissions these energetic particles produce. This is accomplished through the combination of high-resolution spectroscopy and spectroscopic imaging, including the first images of flares in gamma rays. RHESSI has observed over 12,000 solar flares since its launch on February 5, 2002. I will demonstrate how we use the RHESSI spectra to deduce physical properties of accelerated electrons and hot plasma in flares. Using images to estimate volumes, w e typically find that the total energy in accelerated electrons is comparable to that in the thermal plasma. I will also present flare observations that provide strong support for the presence of magnetic reconnection in a large-scale, vertical current sheet in the solar corona. RHESSI observations such as these are allowing us to probe more deeply into the physics of solar flares.

  4. Imaging and spectroscopic observations of the 9 March 2016 Total Solar Eclipse in Palangkaraya

    Kholish, Abdul Majid Al; Jihad, Imanul; Andika, Irham Taufik; Puspitaningrum, Evaria; Ainy, Fathin Q.; Ramadhan, Sahlan; Arifyanto, M. Ikbal; Malasan, Hakim L.

    2016-01-01

    The March 9 th 2016 total solar eclipse observation was carried out at Universitas Palangkaraya, Central Kalimantan. Time-resolved imaging of the Sun has been conducted before, after, and during totality of eclipse while optical spectroscopic observation has been carried out only at the totality. The imaging observation in white light was done to take high resolution images of solar corona. The images were taken with a DSLR camera that is attached to a refractor telescope (d=66 mm, f/5.9). Despite cloudy weather during the eclipse moments, we managed to obtain the images with lower signal-to-noise ratio, including identifiable diamond ring, prominence and coronal structure. The images were processed using standard reduction procedure to increase the signal-to-noise ratio and to enhance the corona. Then, the coronal structure is determined and compared with ultraviolet data from SOHO to analyze the correlation between visual and ultraviolet corona. The spectroscopic observation was conducted using a slit-less spectrograph and a DSLR camera to obtain solar flash spectra. The flash spectra taken during the eclipse show emissions of H 4861 Å, He I 5876 Å, and H 6563 Å. The Fe XIV 5303 Å and Fe X 6374 Å lines are hardly detected due to low signal-to-noise ratio. Spectral reduction and analysis are conducted to derive the emission lines intensity relative to continuum intensity. We use the measured parameters to determine the temperature of solar chromosphere. (paper)

  5. Hard X-Ray Flare Source Sizes Measured with the Ramaty High Energy Solar Spectroscopic Imager

    Dennis, Brian R.; Pernak, Rick L.

    2009-01-01

    Ramaty High Energy Solar Spectroscopic Imager (RHESSI) observations of 18 double hard X-ray sources seen at energies above 25 keV are analyzed to determine the spatial extent of the most compact structures evident in each case. The following four image reconstruction algorithms were used: Clean, Pixon, and two routines using visibilities maximum entropy and forward fit (VFF). All have been adapted for this study to optimize their ability to provide reliable estimates of the sizes of the more compact sources. The source fluxes, sizes, and morphologies obtained with each method are cross-correlated and the similarities and disagreements are discussed. The full width at half-maximum (FWHM) of the major axes of the sources with assumed elliptical Gaussian shapes are generally well correlated between the four image reconstruction routines and vary between the RHESSI resolution limit of approximately 2" up to approximately 20" with most below 10". The FWHM of the minor axes are generally at or just above the RHESSI limit and hence should be considered as unresolved in most cases. The orientation angles of the elliptical sources are also well correlated. These results suggest that the elongated sources are generally aligned along a flare ribbon with the minor axis perpendicular to the ribbon. This is verified for the one flare in our list with coincident Transition Region and Coronal Explorer (TRACE) images. There is evidence for significant extra flux in many of the flares in addition to the two identified compact sources, thus rendering the VFF assumption of just two Gaussians inadequate. A more realistic approximation in many cases would be of two line sources with unresolved widths. Recommendations are given for optimizing the RHESSI imaging reconstruction process to ensure that the finest possible details of the source morphology become evident and that reliable estimates can be made of the source dimensions.

  6. Utilization of Solar Dynamics Observatory space weather digital image data for comparative analysis with application to Baryon Oscillation Spectroscopic Survey

    Shekoyan, V.; Dehipawala, S.; Liu, Ernest; Tulsee, Vivek; Armendariz, R.; Tremberger, G.; Holden, T.; Marchese, P.; Cheung, T.

    2012-10-01

    Digital solar image data is available to users with access to standard, mass-market software. Many scientific projects utilize the Flexible Image Transport System (FITS) format, which requires specialized software typically used in astrophysical research. Data in the FITS format includes photometric and spatial calibration information, which may not be useful to researchers working with self-calibrated, comparative approaches. This project examines the advantages of using mass-market software with readily downloadable image data from the Solar Dynamics Observatory for comparative analysis over with the use of specialized software capable of reading data in the FITS format. Comparative analyses of brightness statistics that describe the solar disk in the study of magnetic energy using algorithms included in mass-market software have been shown to give results similar to analyses using FITS data. The entanglement of magnetic energy associated with solar eruptions, as well as the development of such eruptions, has been characterized successfully using mass-market software. The proposed algorithm would help to establish a publicly accessible, computing network that could assist in exploratory studies of all FITS data. The advances in computer, cell phone and tablet technology could incorporate such an approach readily for the enhancement of high school and first-year college space weather education on a global scale. Application to ground based data such as that contained in the Baryon Oscillation Spectroscopic Survey is discussed.

  7. A New Method to Comprehensively Diagnose Shock Waves in the Solar Atmosphere Based on Simultaneous Spectroscopic and Imaging Observations

    Ruan, Wenzhi; Yan, Limei; He, Jiansen; Zhang, Lei; Wang, Linghua; Wei, Yong

    2018-06-01

    Shock waves are believed to play an important role in plasma heating. The shock-like temporal jumps in radiation intensity and Doppler shift have been identified in the solar atmosphere. However, a quantitative diagnosis of the shocks in the solar atmosphere is still lacking, seriously hindering the understanding of shock dissipative heating of the solar atmosphere. Here, we propose a new method to realize the goal of the shock quantitative diagnosis, based on Rankine–Hugoniot equations and taking the advantages of simultaneous imaging and spectroscopic observations from, e.g., IRIS (Interface Region Imaging Spectrograph). Because of this method, the key parameters of shock candidates can be derived, such as the bulk velocity and temperature of the plasma in the upstream and downstream, the propagation speed and direction. The method is applied to the shock candidates observed by IRIS, and the overall characteristics of the shocks are revealed quantitatively for the first time. This method is also tested with the help of forward modeling, i.e., virtual observations of simulated shocks. The parameters obtained from the method are consistent with the parameters of the shock formed in the model and are independent of the viewing direction. Therefore, the method we proposed here is applicable to the quantitative and comprehensive diagnosis of the observed shocks in the solar atmosphere.

  8. Spectroscopic imaging of photopotentials and photoinduced potential fluctuations in a bulk heterojunction solar cell film.

    Luria, Justin L; Hoepker, Nikolas; Bruce, Robert; Jacobs, Andrew R; Groves, Chris; Marohn, John A

    2012-11-27

    We present spatially resolved photovoltage spectra of a bulk heterojunction solar cell film composed of phase-separated poly(9,9'-dioctylfluorene-co-benzothiadiazole) (F8BT) and poly(9,9'-dioctylfluorene-co-bis-N,N'-(4-butylphenyl)-bis-N,N'-phenyl-1,4-phenylenediamine) (PFB) polymers prepared on ITO/PEDOT:PSS and aluminum substrates. Over both PFB- and F8BT-rich domains, the photopotential spectra were found to be proportional to a linear combination of the polymers' absorption spectra. Charge trapping in the film was studied using photopotential fluctuation spectroscopy, in which low-frequency photoinduced electrostatic potential fluctuations were measured by observing noise in the oscillation frequency of a nearby charged atomic force microscope cantilever. Over both F8BT- and PFB-rich regions, the magnitude, distance dependence, frequency dependence, and illumination wavelength dependence of the observed cantilever frequency noise are consistent with photopotential fluctuations arising from stochastic light-driven trapping and detrapping of charges in F8BT. Taken together, our findings suggest a microscopic mechanism by which intermixing of phases leads to charge trapping and thereby to suppressed open-circuit voltage and decreased efficiency in this prototypical bulk heterojunction solar cell film.

  9. Development of a THz spectroscopic imaging system

    Usami, M; Iwamoto, T; Fukasawa, R; Tani, M; Watanabe, M; Sakai, K

    2002-01-01

    We have developed a real-time THz imaging system based on the two-dimensional (2D) electro-optic (EO) sampling technique. Employing the 2D EO-sampling technique, we can obtain THz images using a CCD camera at a video rate of up to 30 frames per second. A spatial resolution of 1.4 mm was achieved. This resolution was reasonably close to the theoretical limit determined by diffraction. We observed not only static objects but also moving ones. To acquire spectroscopic information, time-domain images were collected. By processing these images on a computer, we can obtain spectroscopic images. Spectroscopy for silicon wafers was demonstrated

  10. Enhancing forensic science with spectroscopic imaging

    Ricci, Camilla; Kazarian, Sergei G.

    2006-09-01

    This presentation outlines the research we are developing in the area of Fourier Transform Infrared (FTIR) spectroscopic imaging with the focus on materials of forensic interest. FTIR spectroscopic imaging has recently emerged as a powerful tool for characterisation of heterogeneous materials. FTIR imaging relies on the ability of the military-developed infrared array detector to simultaneously measure spectra from thousands of different locations in a sample. Recently developed application of FTIR imaging using an ATR (Attenuated Total Reflection) mode has demonstrated the ability of this method to achieve spatial resolution beyond the diffraction limit of infrared light in air. Chemical visualisation with enhanced spatial resolution in micro-ATR mode broadens the range of materials studied with FTIR imaging with applications to pharmaceutical formulations or biological samples. Macro-ATR imaging has also been developed for chemical imaging analysis of large surface area samples and was applied to analyse the surface of human skin (e.g. finger), counterfeit tablets, textile materials (clothing), etc. This approach demonstrated the ability of this imaging method to detect trace materials attached to the surface of the skin. This may also prove as a valuable tool in detection of traces of explosives left or trapped on the surfaces of different materials. This FTIR imaging method is substantially superior to many of the other imaging methods due to inherent chemical specificity of infrared spectroscopy and fast acquisition times of this technique. Our preliminary data demonstrated that this methodology will provide the means to non-destructive detection method that could relate evidence to its source. This will be important in a wider crime prevention programme. In summary, intrinsic chemical specificity and enhanced visualising capability of FTIR spectroscopic imaging open a window of opportunities for counter-terrorism and crime-fighting, with applications ranging

  11. Highlights of the Brazilian Solar Spectroscope

    Sawant, H. S.; Cecatto, J.R.; Mészárosová, Hana; Faria, C.; Fernandes, F. C. R.; Karlický, Marian; de Andrade, M. C.

    2009-01-01

    Roč. 44, č. 1 (2009), s. 54-57 ISSN 0273-1177 R&D Projects: GA AV ČR IAA300030701 Institutional research plan: CEZ:AV0Z10030501 Keywords : Sun istrumentation * spectroscope * corona * radio radiation Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 1.079, year: 2009

  12. Spectroscopic and imaging diagnostics of pulsed laser deposition laser plasmas

    Thareja, Raj K.

    2002-01-01

    An overview of laser spectroscopic techniques used in the diagnostics of laser ablated plumes used for thin film deposition is given. An emerging laser spectroscopic imaging technique for the laser ablation material processing is discussed. (author)

  13. Noise Gating Solar Images

    DeForest, Craig; Seaton, Daniel B.; Darnell, John A.

    2017-08-01

    I present and demonstrate a new, general purpose post-processing technique, "3D noise gating", that can reduce image noise by an order of magnitude or more without effective loss of spatial or temporal resolution in typical solar applications.Nearly all scientific images are, ultimately, limited by noise. Noise can be direct Poisson "shot noise" from photon counting effects, or introduced by other means such as detector read noise. Noise is typically represented as a random variable (perhaps with location- or image-dependent characteristics) that is sampled once per pixel or once per resolution element of an image sequence. Noise limits many aspects of image analysis, including photometry, spatiotemporal resolution, feature identification, morphology extraction, and background modeling and separation.Identifying and separating noise from image signal is difficult. The common practice of blurring in space and/or time works because most image "signal" is concentrated in the low Fourier components of an image, while noise is evenly distributed. Blurring in space and/or time attenuates the high spatial and temporal frequencies, reducing noise at the expense of also attenuating image detail. Noise-gating exploits the same property -- "coherence" -- that we use to identify features in images, to separate image features from noise.Processing image sequences through 3-D noise gating results in spectacular (more than 10x) improvements in signal-to-noise ratio, while not blurring bright, resolved features in either space or time. This improves most types of image analysis, including feature identification, time sequence extraction, absolute and relative photometry (including differential emission measure analysis), feature tracking, computer vision, correlation tracking, background modeling, cross-scale analysis, visual display/presentation, and image compression.I will introduce noise gating, describe the method, and show examples from several instruments (including SDO

  14. Infrared Spectroscopic Imaging: The Next Generation

    Bhargava, Rohit

    2013-01-01

    Infrared (IR) spectroscopic imaging seemingly matured as a technology in the mid-2000s, with commercially successful instrumentation and reports in numerous applications. Recent developments, however, have transformed our understanding of the recorded data, provided capability for new instrumentation, and greatly enhanced the ability to extract more useful information in less time. These developments are summarized here in three broad areas— data recording, interpretation of recorded data, and information extraction—and their critical review is employed to project emerging trends. Overall, the convergence of selected components from hardware, theory, algorithms, and applications is one trend. Instead of similar, general-purpose instrumentation, another trend is likely to be diverse and application-targeted designs of instrumentation driven by emerging component technologies. The recent renaissance in both fundamental science and instrumentation will likely spur investigations at the confluence of conventional spectroscopic analyses and optical physics for improved data interpretation. While chemometrics has dominated data processing, a trend will likely lie in the development of signal processing algorithms to optimally extract spectral and spatial information prior to conventional chemometric analyses. Finally, the sum of these recent advances is likely to provide unprecedented capability in measurement and scientific insight, which will present new opportunities for the applied spectroscopist. PMID:23031693

  15. Spectroscopic Needs for Imaging Dark Energy Experiments

    Newman, Jeffrey A.; Abate, Alexandra; Abdalla, Filipe B.; Allam, Sahar; Allen, Steven W.; Ansari, Reza; Bailey, Stephen; Barkhouse, Wayne A.; Beers, Timothy C.; Blanton, Michael R.; Brodwin, Mark; Brownstein, Joel R.; Brunner, Robert J.; Carrasco-Kind, Matias; Cervantes-Cota, Jorge; Chisari, Nora Elisa; Colless, Matthew; Coupon, Jean; Cunha, Carlos E.; Frye, Brenda L.; Gawiser, Eric J.; Gehrels, Neil; Grady, Kevin; Hagen, Alex; Hall, Patrick B.; Hearin, Andrew P.; Hildebrandt, Hendrik; Hirata, Christopher M.; Ho, Shirley; Huterer, Dragan; Ivezic, Zeljko; Kneib, Jean-Paul; Kruk, Jeffrey W.; Lahav, Ofer; Mandelbaum, Rachel; Matthews, Daniel J.; Miquel, Ramon; Moniez, Marc; Moos, H. W.; Moustakas, John; Papovich, Casey; Peacock, John A.; Rhodes, Jason; Ricol, Jean-Stepane; Sadeh, Iftach; Schmidt, Samuel J.; Stern, Daniel K.; Tyson, J. Anthony; Von der Linden, Anja; Wechsler, Risa H.; Wood-Vasey, W. M.; Zentner, A.

    2015-01-01

    Ongoing and near-future imaging-based dark energy experiments are critically dependent upon photometric redshifts (a.k.a. photo-z's): i.e., estimates of the redshifts of objects based only on flux information obtained through broad filters. Higher-quality, lower-scatter photo-z's will result in smaller random errors on cosmological parameters; while systematic errors in photometric redshift estimates, if not constrained, may dominate all other uncertainties from these experiments. The desired optimization and calibration is dependent upon spectroscopic measurements for secure redshift information; this is the key application of galaxy spectroscopy for imaging-based dark energy experiments. Hence, to achieve their full potential, imaging-based experiments will require large sets of objects with spectroscopically-determined redshifts, for two purposes: Training: Objects with known redshift are needed to map out the relationship between object color and z (or, equivalently, to determine empirically-calibrated templates describing the rest-frame spectra of the full range of galaxies, which may be used to predict the color-z relation). The ultimate goal of training is to minimize each moment of the distribution of differences between photometric redshift estimates and the true redshifts of objects, making the relationship between them as tight as possible. The larger and more complete our ''training set'' of spectroscopic redshifts is, the smaller the RMS photo-z errors should be, increasing the constraining power of imaging experiments; Requirements: Spectroscopic redshift measurements for ∼30,000 objects over >∼15 widely-separated regions, each at least ∼20 arcmin in diameter, and reaching the faintest objects used in a given experiment, will likely be necessary if photometric redshifts are to be trained and calibrated with conventional techniques. Larger, more complete samples (i.e., with longer exposure times) can improve photo

  16. 2-d spectroscopic imaging of brain tumours

    Ferris, N.J.; Brotchie, P.R.

    2002-01-01

    Full text: This poster illustrates the use of two-dimensional spectroscopic imaging (2-D SI) in the characterisation of brain tumours, and the monitoring of subsequent treatment. After conventional contrast-enhanced MR imaging of patients with known or suspected brain tumours, 2-D SI is performed at a single axial level. The level is chosen to include the maximum volume of abnormal enhancement, or, in non-enhancing lesions. The most extensive T2 signal abnormality. Two different MR systems have been used (Marconi Edge and GE Signa LX); at each site, a PRESS localisation sequence is employed with TE 128-144 ms. Automated software is used to generate spectral arrays, metabolite maps, and metabolite ratio maps from the spectroscopic data. Colour overlays of the maps onto anatomical images are produced using manufacturer software or the Medex imaging data analysis package. High grade gliomas showed choline levels higher than those in apparently normal brain, with decreases in NAA and creatine. Some lesions showed spectral abnormality extending into otherwise normal appearing brain. This was also seen in a case of CNS lymphoma. Lowgrade lesions showed choline levels similar to normal brain, but with decreased NAA. Only a small number of metastases have been studied, but to date no metastasis has shown spectral abnormality beyond the margins suggested by conventional imaging. Follow-up studies generally show spectral heterogeneity. Regions with choline levels higher than those in normal-appearing brain are considered to represent recurrent high-grade tumour. Some regions show choline to be the dominant metabolite, but its level is not greater than that seen in normal brain. These regions are considered suspicious for residual / recurrent tumour when the choline / creatine ratio exceeds 2 (lower ratios may represent treatment effect). 2-D SI improves the initial assessment of brain tumours, and has potential for influencing the radiotherapy treatment strategy. 2-D SI also

  17. A subspace approach to high-resolution spectroscopic imaging.

    Lam, Fan; Liang, Zhi-Pei

    2014-04-01

    To accelerate spectroscopic imaging using sparse sampling of (k,t)-space and subspace (or low-rank) modeling to enable high-resolution metabolic imaging with good signal-to-noise ratio. The proposed method, called SPectroscopic Imaging by exploiting spatiospectral CorrElation, exploits a unique property known as partial separability of spectroscopic signals. This property indicates that high-dimensional spectroscopic signals reside in a very low-dimensional subspace and enables special data acquisition and image reconstruction strategies to be used to obtain high-resolution spatiospectral distributions with good signal-to-noise ratio. More specifically, a hybrid chemical shift imaging/echo-planar spectroscopic imaging pulse sequence is proposed for sparse sampling of (k,t)-space, and a low-rank model-based algorithm is proposed for subspace estimation and image reconstruction from sparse data with the capability to incorporate prior information and field inhomogeneity correction. The performance of the proposed method has been evaluated using both computer simulations and phantom studies, which produced very encouraging results. For two-dimensional spectroscopic imaging experiments on a metabolite phantom, a factor of 10 acceleration was achieved with a minimal loss in signal-to-noise ratio compared to the long chemical shift imaging experiments and with a significant gain in signal-to-noise ratio compared to the accelerated echo-planar spectroscopic imaging experiments. The proposed method, SPectroscopic Imaging by exploiting spatiospectral CorrElation, is able to significantly accelerate spectroscopic imaging experiments, making high-resolution metabolic imaging possible. Copyright © 2014 Wiley Periodicals, Inc.

  18. A SOLAR SPECTROSCOPIC ABSOLUTE ABUNDANCE OF ARGON FROM RESIK

    Sylwester, J.; Sylwester, B.; Phillips, K. J. H.; Kuznetsov, V. D.

    2010-01-01

    Observations of He-like and H-like Ar (Ar XVII and Ar XVIII) lines at 3.949 A and 3.733 A, respectively, with the RESIK X-ray spectrometer on the CORONAS-F spacecraft, together with temperatures and emission measures from the two channels of GOES, have been analyzed to obtain the abundance of Ar in flare plasmas in the solar corona. The line fluxes per unit emission measure show a temperature dependence like that predicted from theory and lead to spectroscopically determined values for the absolute Ar abundance, A(Ar) = 6.44 ± 0.07 (Ar XVII) and 6.49 ± 0.16 (Ar XVIII), which are in agreement to within uncertainties. The weighted mean is 6.45 ± 0.06, which is between two recent compilations of the solar Ar abundance and suggests that the photospheric and coronal abundances of Ar are very similar.

  19. Single-Shot MR Spectroscopic Imaging with Partial Parallel Imaging

    Posse, Stefan; Otazo, Ricardo; Tsai, Shang-Yueh; Yoshimoto, Akio Ernesto; Lin, Fa-Hsuan

    2010-01-01

    An MR spectroscopic imaging (MRSI) pulse sequence based on Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI) is introduced that measures 2-dimensional metabolite maps in a single excitation. Echo-planar spatial-spectral encoding was combined with interleaved phase encoding and parallel imaging using SENSE to reconstruct absorption mode spectra. The symmetrical k-space trajectory compensates phase errors due to convolution of spatial and spectral encoding. Single-shot MRSI at short TE was evaluated in phantoms and in vivo on a 3 T whole body scanner equipped with 12-channel array coil. Four-step interleaved phase encoding and 4-fold SENSE acceleration were used to encode a 16×16 spatial matrix with 390 Hz spectral width. Comparison with conventional PEPSI and PEPSI with 4-fold SENSE acceleration demonstrated comparable sensitivity per unit time when taking into account g-factor related noise increases and differences in sampling efficiency. LCModel fitting enabled quantification of Inositol, Choline, Creatine and NAA in vivo with concentration values in the ranges measured with conventional PEPSI and SENSE-accelerated PEPSI. Cramer-Rao lower bounds were comparable to those obtained with conventional SENSE-accelerated PEPSI at the same voxel size and measurement time. This single-shot MRSI method is therefore suitable for applications that require high temporal resolution to monitor temporal dynamics or to reduce sensitivity to tissue movement. PMID:19097245

  20. THE YOUNG SOLAR ANALOGS PROJECT. I. SPECTROSCOPIC AND PHOTOMETRIC METHODS AND MULTI-YEAR TIMESCALE SPECTROSCOPIC RESULTS

    Gray, R. O.; Briley, M. M.; Lambert, R. A.; Fuller, V. A.; Newsome, I. M.; Seeds, M. F. [Department of Physics and Astronomy, Appalachian State University, Boone, NC 26808 (United States); Saken, J. M.; Kahvaz, Y. [Department of Physics and Physical Science, Marshall University, Huntington, WV 25755 (United States); Corbally, C. J. [Vatican Observatory Research Group, Steward Observatory, Tucson, AZ 85721-0065 (United States)

    2015-12-15

    This is the first in a series of papers presenting methods and results from the Young Solar Analogs Project, which began in 2007. This project monitors both spectroscopically and photometrically a set of 31 young (300–1500 Myr) solar-type stars with the goal of gaining insight into the space environment of the Earth during the period when life first appeared. From our spectroscopic observations we derive the Mount Wilson S chromospheric activity index (S{sub MW}), and describe the method we use to transform our instrumental indices to S{sub MW} without the need for a color term. We introduce three photospheric indices based on strong absorption features in the blue-violet spectrum—the G-band, the Ca i resonance line, and the Hydrogen-γ line—with the expectation that these indices might prove to be useful in detecting variations in the surface temperatures of active solar-type stars. We also describe our photometric program, and in particular our “Superstar technique” for differential photometry which, instead of relying on a handful of comparison stars, uses the photon flux in the entire star field in the CCD image to derive the program star magnitude. This enables photometric errors on the order of 0.005–0.007 magnitude. We present time series plots of our spectroscopic data for all four indices, and carry out extensive statistical tests on those time series demonstrating the reality of variations on timescales of years in all four indices. We also statistically test for and discover correlations and anti-correlations between the four indices. We discuss the physical basis of those correlations. As it turns out, the “photospheric” indices appear to be most strongly affected by emission in the Paschen continuum. We thus anticipate that these indices may prove to be useful proxies for monitoring emission in the ultraviolet Balmer continuum. Future papers in this series will discuss variability of the program stars on medium (days–months) and short

  1. Solar Image Analysis and Visualization

    Ireland, J

    2009-01-01

    This volume presents a selection of papers on the state of the art of image enhancement, automated feature detection, machine learning, and visualization tools in support of solar physics that focus on the challenges presented by new ground-based and space-based instrumentation. The articles and topics were inspired by the Third Solar Image Processing Workshop, held at Trinity College Dublin, Ireland but contributions from other experts have been included as well. This book is mainly aimed at researchers and graduate students working on image processing and compter vision in astronomy and solar physics.

  2. The convective noise floor for the spectroscopic detection of low mass companions to solar type stars

    Deming, D.; Espenak, F.; Jennings, D. E.; Brault, J. W.

    1986-01-01

    The threshold mass for the unambiguous spectroscopic detection of low mass companions to solar type stars is defined here as the time when the maximum acceleration in the stellar radial velocity due to the Doppler reflex of the companion exceeds the apparent acceleration produced by changes in convection. An apparent acceleration of 11 m/s/yr in integrated sunlight was measured using near infrared Fourier transform spectroscopy. This drift in the apparent solar velocity is attributed to a lessening in the magnetic inhibition of granular convection as solar minimum approaches. The threshold mass for spectroscopic detection of companions to a one solar mass star is estimated at below one Jupiter mass.

  3. Chemical mapping of pharmaceutical cocrystals using terahertz spectroscopic imaging.

    Charron, Danielle M; Ajito, Katsuhiro; Kim, Jae-Young; Ueno, Yuko

    2013-02-19

    Terahertz (THz) spectroscopic imaging is a promising technique for distinguishing pharmaceuticals of similar molecular composition but differing crystal structures. Physicochemical properties, for instance bioavailability, are manipulated by altering a drug's crystal structure through methods such as cocrystallization. Cocrystals are molecular complexes having crystal structures different from those of their pure components. A technique for identifying the two-dimensional distribution of these alternate forms is required. Here we present the first demonstration of THz spectroscopic imaging of cocrystals. THz spectra of caffeine-oxalic acid cocrystal measured at low temperature exhibit sharp peaks, enabling us to visualize the cocrystal distribution in nonuniform tablets. The cocrystal distribution was clearly identified using THz spectroscopic data, and the cocrystal concentration was calculated with 0.3-1.3% w/w error from the known total concentration. From this result, THz spectroscopy allows quantitative chemical mapping of cocrystals and offers researchers and drug developers a new analytical tool.

  4. Probing superconductors. Spectroscopic-imaging scanning tunneling microscopy

    Hanaguri, Tetsuo

    2011-01-01

    Discovery of high-temperature superconductivity in a cuprate triggered developments of various spectroscopic tools which have been utilized to elucidate electronic states of this mysterious compound. Particularly, angle-resolved photoemission spectroscopy and scanning-tunneling microscopy/spectroscopy are improved considerably. It is now possible to map the superconducting gap in both momentum and real spaces using these two techniques. Here we review spectroscopic-imaging scanning tunneling microscopy which is able to explore momentum-space phase structure of the superconducting gap, as well as real-space structure. Applications of this technique to a cuprate and an iron-based superconductor are discussed. (author)

  5. Automated processing for proton spectroscopic imaging using water reference deconvolution.

    Maudsley, A A; Wu, Z; Meyerhoff, D J; Weiner, M W

    1994-06-01

    Automated formation of MR spectroscopic images (MRSI) is necessary before routine application of these methods is possible for in vivo studies; however, this task is complicated by the presence of spatially dependent instrumental distortions and the complex nature of the MR spectrum. A data processing method is presented for completely automated formation of in vivo proton spectroscopic images, and applied for analysis of human brain metabolites. This procedure uses the water reference deconvolution method (G. A. Morris, J. Magn. Reson. 80, 547(1988)) to correct for line shape distortions caused by instrumental and sample characteristics, followed by parametric spectral analysis. Results for automated image formation were found to compare favorably with operator dependent spectral integration methods. While the water reference deconvolution processing was found to provide good correction of spatially dependent resonance frequency shifts, it was found to be susceptible to errors for correction of line shape distortions. These occur due to differences between the water reference and the metabolite distributions.

  6. Designing and manufacturing of solar imaging and tracking system

    Mehrdad Hosseini

    2017-11-01

    Full Text Available Abstract – in this study, designing and manufacturing of solar imaging and tracking system in order to research and spectroscopy applications are investigated. The device has the ability to be used as a Telescope, spectroscope, spectrophotometer and spectrohelioscope. The results obtained from this device are used in the various field of research such as absorption spectra of the surface of the sun, transit of planets in front of the sun, Doppler effects, evaluation of the Fraunhofer lines, plot of intensity versus wavelength and studying of Solar Flares. In this research, design and manufacture of the device, along with some of the results, are reported.

  7. Immunocytochemistry by electron spectroscopic imaging using a homogeneously boronated peptide.

    Kessels, M M; Qualmann, B; Klobasa, F; Sierralta, W D

    1996-05-01

    A linear all-L-oligopeptide containing five carboranyl amino acids (corresponding to 50 boron atoms) was synthesized and specifically attached to the free thiol group of monovalent antibody fragments F(ab)'. The boronated immunoreagent was used for the direct post-embedding detection of somatotrophic hormone in ultrathin sections of porcine pituitary embedded in Spurr resin. The specific boron-labelling of secretory vesicles in somatotrophs was detected by electron spectroscopic imaging and confirmed by conventional immunogold labelling run in parallel. In comparison with immunogold, boron-labelled F(ab)'-fragments showed higher tagging frequencies, as was expected; the small uncharged immunoreagents have an elongated shape and carry the antigen-combining structure and the detection tag at opposite ends, thus allowing for high spatial resolution in electron spectroscopic imaging.

  8. Spectroscopic AC susceptibility imaging (sASI) of magnetic nanoparticles

    Ficko, Bradley W.; Nadar, Priyanka M.; Diamond, Solomon G.

    2015-01-01

    This study demonstrates a method for alternating current (AC) susceptibility imaging (ASI) of magnetic nanoparticles (mNPs) using low cost instrumentation. The ASI method uses AC magnetic susceptibility measurements to create tomographic images using an array of drive coils, compensation coils and fluxgate magnetometers. Using a spectroscopic approach in conjunction with ASI, a series of tomographic images can be created for each frequency measurement set and is termed sASI. The advantage of sASI is that mNPs can be simultaneously characterized and imaged in a biological medium. System calibration was performed by fitting the in-phase and out-of-phase susceptibility measurements of an mNP sample with a hydrodynamic diameter of 100 nm to a Brownian relaxation model (R 2 =0.96). Samples of mNPs with core diameters of 10 and 40 nm and a sample of 100 nm hydrodynamic diameter were prepared in 0.5 ml tubes. Three mNP samples were arranged in a randomized array and then scanned using sASI with six frequencies between 425 and 925 Hz. The sASI scans showed the location and quantity of the mNP samples (R 2 =0.97). Biological compatibility of the sASI method was demonstrated by scanning mNPs that were injected into a pork sausage. The mNP response in the biological medium was found to correlate with a calibration sample (R 2 =0.97, p<0.001). These results demonstrate the concept of ASI and advantages of sASI. - Highlights: • Development of an AC susceptibility imaging model. • Comparison of AC susceptibility imaging (ASI) and susceptibility magnitude imaging (SMI). • Demonstration of ASI and spectroscopic ASI (sASI) using three different magnetic nanoparticle types. • SASI scan separation of three different magnetic nanoparticles samples using 5 spectroscopic frequencies. • Demonstration of biological feasibility of sASI

  9. Imaging spectroscopic analysis at the Advanced Light Source

    MacDowell, A. A.; Warwick, T.; Anders, S.; Lamble, G.M.; Martin, M.C.; McKinney, W.R.; Padmore, H.A.

    1999-01-01

    One of the major advances at the high brightness third generation synchrotrons is the dramatic improvement of imaging capability. There is a large multi-disciplinary effort underway at the ALS to develop imaging X-ray, UV and Infra-red spectroscopic analysis on a spatial scale from. a few microns to 10nm. These developments make use of light that varies in energy from 6meV to 15KeV. Imaging and spectroscopy are finding applications in surface science, bulk materials analysis, semiconductor structures, particulate contaminants, magnetic thin films, biology and environmental science. This article is an overview and status report from the developers of some of these techniques at the ALS. The following table lists all the currently available microscopes at the. ALS. This article will describe some of the microscopes and some of the early applications

  10. Proton magnetic resonance spectroscopic imaging in neurodegenerative diseases

    Schuff, Norbert; Vermathen, Peter; Maudsley, Andrew A.; Weiner, Michael W.

    1999-01-01

    Proton magnetic resonance spectroscopic imaging ( 1 H MRSI) was used to investigate changes in brain metabolites in Alzheimer's disease, epilepsy, and amyotrophic lateral sclerosis. Examples of results from several ongoing clinical studies are provided. Multislice 1 H MRSI of the human brain, without volume pre selection offers considerable advantage over previously available techniques. Furthermore, MRI tissue segmentation and completely automated spectral curve fitting greatly facilitate quantitative data analysis. Future efforts will be devoted to obtain full volumetric brain coverage and data acquisition at short spin-echo times (TE<30 ms) for the detection of metabolites. (author)

  11. Two Solar Tornadoes Observed with the Interface Region Imaging Spectrograph

    Yang, Zihao; Tian, Hui; Peter, Hardi; Su, Yang; Samanta, Tanmoy; Zhang, Jingwen; Chen, Yajie

    2018-01-01

    The barbs or legs of some prominences show an apparent motion of rotation, which are often termed solar tornadoes. It is under debate whether the apparent motion is a real rotating motion, or caused by oscillations or counter-streaming flows. We present analysis results from spectroscopic observations of two tornadoes by the Interface Region Imaging Spectrograph. Each tornado was observed for more than 2.5 hr. Doppler velocities are derived through a single Gaussian fit to the Mg II k 2796 Å and Si IV 1393 Å line profiles. We find coherent and stable redshifts and blueshifts adjacent to each other across the tornado axes, which appears to favor the interpretation of these tornadoes as rotating cool plasmas with temperatures of 104 K–105 K. This interpretation is further supported by simultaneous observations of the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory, which reveal periodic motions of dark structures in the tornadoes. Our results demonstrate that spectroscopic observations can provide key information to disentangle different physical processes in solar prominences.

  12. Spectroscopic Identification of Cool White Dwarfs in the Solar Neighborhood

    Kawka, Adela; Vennes, S.

    2006-01-01

    Roč. 643, č. 1 (2006), s. 402-415 ISSN 0004-637X R&D Projects: GA ČR GP205/05/P186 Institutional research plan: CEZ:AV0Z10030501 Keywords : white dwarfs * solar neighborhood * atmospheres Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 6.119, year: 2006

  13. Fatty infiltration of the liver: evaluation by proton spectroscopic imaging

    Heiken, J.P.; Lee, J.K.; Dixon, W.T.

    1985-01-01

    The reliability of proton spectroscopic imaging in evaluating fatty infiltration of the liver was investigated in 35 subjects (12 healthy volunteers and 23 patients with fatty livers). With this modified spin-echo technique, fatty liver could be separated from normal liver both visually and quantitatively. On the opposed image, normal liver had an intermediate signal intensity, greater than that of muscle, whereas fatty liver had a lower signal intensity, equal to or less than that of muscle. In normal livers, the lipid signal fraction was less than 10%, while in fatty livers it was greater than 10% and usually exceeded 20%. With this technique, nonuniform fatty infiltration of the liver can be differentiated from hepatic metastases, and the technique may prove useful in the differentiation of some hepatic disorders

  14. Spectroscopic imaging of X-rays anew look

    Heijne, Erik H M

    2003-01-01

    In recent hybrid imaging devices a segmented (50-100mum) semiconductor sensor matrix is matched to a separate readout chip made in some standard silicon CMOS technology. The large number of contacts are made by high-density bump bonding interconnect technology. Extended functionality with hundreds of transistors in each electronics cell can serve a variety of purposes. Fluctuations in the response of the sensor matrix can be compensated in real-time. A single photon processing circuit in each pixel can achieve spectroscopic imaging by energy measurement even at high rates. However, it is necessary to take into account the distribution of the signals over adjacent pixels. Another possibility is the discrimination by energy of photon conversions in stacked layers with increasing absorption.

  15. In Vivo H MR spectroscopic imaging of human brain

    Choe, Bo Young; Suh, Tae Suk; Choi, Kyo Ho; Bahk, Yong Whee; Shinn, Kyung Sub

    1994-01-01

    To evaluate the spatial distribution of various proton metabolites in the human brain with use of water-suppressed in vivo H MR spectroscopic imaging (MRSI) technique. All of water-suppressed in vivo H MRSI were performed on 1.5 T whole-body MRI/MRS system using Stimulated Echo Acquisition Method (STEAM) Chemical Shift Imaging (CSI) pulse sequence. T1-weighted MR images were used for CSI field of view (FOV; 24 cm). Voxel size of 1.5 cm 3 was designated from the periphery of the brain which was divided by 1024 X 16 X 16 data points. Metabolite images of N-acetylaspartate (NAA), creatine/ phosphocreatine (Cr) + choline/phosphocholine (Cho), and complex of γ-aminobutyric acid (GABA) + glutamate (Glu) were obtained on the human brain. Our preliminary study suggests that in vivo H MRSI could provide the metabolite imaging to compensate for hypermetabolism on Positron Emission Tomography (PET) scans on the basis of the metabolic informations on brain tissues. The unique ability of in vivo H MRSI to offer noninvasive information about tissue biochemistry in disease states will stimulate on clinical research and disease diagnosis

  16. 3D-Mössbauer spectroscopic microscope for mc-Si solar cell evaluation

    Ino, Y., E-mail: y-ino@ob.sist.ac.jp; Soejima, H.; Hayakawa, K.; Yukihira, K.; Tanaka, K.; Fujita, H.; Watanabe, T. [Shizuoka Institute of Science and Technology (Japan); Ogai, K.; Moriguchi, K.; Harada, Y. [APCO. Ltd. (Japan); Yoshida, Y. [Shizuoka Institute of Science and Technology (Japan)

    2016-12-15

    A 3D-Mössbauer Spectroscopic Microscope is developed to evaluate Fe impurities in multi-crystalline Si solar cells, which combines the Mössbauer spectroscopic microscope with a scanning electron microscope (SEM), an electron beam induced current (EBIC), an electron backscatter diffraction (EBSD), and an electron energy analyzer (HV-CSA). In addition, a new moving-coil-actuator with a liner encoder of 100 nm-resolution is incorporated for the operations with both a constant velocity and a constant acceleration mode successfully with the same precision as that obtained by the conventional transducers. Furthermore, a new multi-capillary X-ray lens is designed to achieve a γ-ray spot size less than 100 μm in diameter. The new microscope provides us to investigate the space correlation between Fe impurities and the lattice defects such as grain boundaries in multi-crystalline Si solar cells.

  17. Recovering the fine structures in solar images

    Karovska, Margarita; Habbal, S. R.; Golub, L.; Deluca, E.; Hudson, Hugh S.

    1994-01-01

    Several examples of the capability of the blind iterative deconvolution (BID) technique to recover the real point spread function, when limited a priori information is available about its characteristics. To demonstrate the potential of image post-processing for probing the fine scale and temporal variability of the solar atmosphere, the BID technique is applied to different samples of solar observations from space. The BID technique was originally proposed for correction of the effects of atmospheric turbulence on optical images. The processed images provide a detailed view of the spatial structure of the solar atmosphere at different heights in regions with different large-scale magnetic field structures.

  18. Spectroscopic Measurements of the Ion Velocity Distribution at the Base of the Fast Solar Wind

    Jeffrey, Natasha L. S.; Hahn, Michael; Savin, Daniel W.; Fletcher, Lyndsay

    2018-03-01

    In situ measurements of the fast solar wind reveal non-thermal distributions of electrons, protons, and minor ions extending from 0.3 au to the heliopause. The physical mechanisms responsible for these non-thermal properties and the location where these properties originate remain open questions. Here, we present spectroscopic evidence, from extreme ultraviolet spectroscopy, that the velocity distribution functions (VDFs) of minor ions are already non-Gaussian at the base of the fast solar wind in a coronal hole, at altitudes of thermal equilibrium, (b) fluid motions such as non-Gaussian turbulent fluctuations or non-uniform wave motions, or (c) some combination of both. These observations provide important empirical constraints for the source region of the fast solar wind and for the theoretical models of the different acceleration, heating, and energy deposition processes therein. To the best of our knowledge, this is the first time that the ion VDF in the fast solar wind has been probed so close to its source region. The findings are also a timely precursor to the upcoming 2018 launch of the Parker Solar Probe, which will provide the closest in situ measurements of the solar wind at approximately 0.04 au (8.5 solar radii).

  19. Reproducibility of P-31 spectroscopic imaging of normal human myocardium

    Tavares, N.J.; Chew, W.; Auffermann, W.; Higgins, C.B.

    1988-01-01

    To assess reproducibility of P-31 MR spectroscopy of human myocardium, ten normal male volunteers were studied on two separate occasions. Spectra were acquired on a clinical 1.5-T MR imaging unit (Signa, General Electric) using a one-dimensional gated spectroscopic imaging sequence (matrix size, 32 X 256) over 20 minutes. Peaks in the adenosine triphosphate (ATP) region, phosphocreatine (PCR), phosphodiesters (PD), and peaks attributable to 2,3 diphosphoglycerate from blood were observed. Interindividual and intraindividual variability expressed as standard errors of the mean (mean +- SEM) were 1.54 +- 0.04 (variability among subjects) and 0.04 (variability between first and second studies) for PCR/β ATP; 0.97 +- 0.18 and 0.06 for PD/β ATP; and 0.62 +- 0.10 and 0.05 for PD/PCR, respectively. In conclusion, P-31 MR spectroscopy yields consistent and reproducible myocardial spectra that might be useful in the future for the evaluation and monitoring of cardiac disease

  20. Magnetic resonance spectroscopic imaging at superresolution: Overview and perspectives.

    Kasten, Jeffrey; Klauser, Antoine; Lazeyras, François; Van De Ville, Dimitri

    2016-02-01

    The notion of non-invasive, high-resolution spatial mapping of metabolite concentrations has long enticed the medical community. While magnetic resonance spectroscopic imaging (MRSI) is capable of achieving the requisite spatio-spectral localization, it has traditionally been encumbered by significant resolution constraints that have thus far undermined its clinical utility. To surpass these obstacles, research efforts have primarily focused on hardware enhancements or the development of accelerated acquisition strategies to improve the experimental sensitivity per unit time. Concomitantly, a number of innovative reconstruction techniques have emerged as alternatives to the standard inverse discrete Fourier transform (DFT). While perhaps lesser known, these latter methods strive to effect commensurate resolution gains by exploiting known properties of the underlying MRSI signal in concert with advanced image and signal processing techniques. This review article aims to aggregate and provide an overview of the past few decades of so-called "superresolution" MRSI reconstruction methodologies, and to introduce readers to current state-of-the-art approaches. A number of perspectives are then offered as to the future of high-resolution MRSI, with a particular focus on translation into clinical settings. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. FIRST SPECTROSCOPIC IMAGING OBSERVATIONS OF THE SUN AT LOW RADIO FREQUENCIES WITH THE MURCHISON WIDEFIELD ARRAY PROTOTYPE

    Oberoi, Divya; Matthews, Lynn D.; Lonsdale, Colin J.; Benkevitch, Leonid; Cairns, Iver H.; Lobzin, Vasili; Emrich, David; Wayth, Randall B.; Arcus, Wayne; Morgan, Edward H.; Williams, Christopher; Prabu, T.; Vedantham, Harish; Williams, Andrew; White, Stephen M.; Allen, G.; Barnes, David; Bernardi, Gianni; Bowman, Judd D.; Briggs, Frank H.

    2011-01-01

    We present the first spectroscopic images of solar radio transients from the prototype for the Murchison Widefield Array, observed on 2010 March 27. Our observations span the instantaneous frequency band 170.9- 201.6 MHz. Though our observing period is characterized as a period of 'low' to 'medium' activity, one broadband emission feature and numerous short-lived, narrowband, non-thermal emission features are evident. Our data represent a significant advance in low radio frequency solar imaging, enabling us to follow the spatial, spectral, and temporal evolution of events simultaneously and in unprecedented detail. The rich variety of features seen here reaffirms the coronal diagnostic capability of low radio frequency emission and provides an early glimpse of the nature of radio observations that will become available as the next generation of low-frequency radio interferometers come online over the next few years.

  2. Clinical stage T1c prostate cancer: evaluation with endorectal MR imaging and MR spectroscopic imaging.

    Zhang, Jingbo; Hricak, Hedvig; Shukla-Dave, Amita; Akin, Oguz; Ishill, Nicole M; Carlino, Lauren J; Reuter, Victor E; Eastham, James A

    2009-11-01

    To assess the diagnostic accuracy of endorectal magnetic resonance (MR) imaging and MR spectroscopic imaging for prediction of the pathologic stage of prostate cancer and the presence of clinically nonimportant disease in patients with clinical stage T1c prostate cancer. The institutional review board approved-and waived the informed patient consent requirement for-this HIPAA-compliant study involving 158 patients (median age, 58 years; age range, 40-76 years) who had clinical stage T1c prostate cancer, had not been treated preoperatively, and underwent combined 1.5-T endorectal MR imaging-MR spectroscopic imaging between January 2003 and March 2004 before undergoing radical prostatectomy. On the MR images and combined endorectal MR-MR spectroscopic images, two radiologists retrospectively and independently rated the likelihood of cancer in 12 prostate regions and the likelihoods of extracapsular extension (ECE), seminal vesicle invasion (SVI), and adjacent organ invasion by using a five-point scale, and they determined the probability of clinically nonimportant prostate cancer by using a four-point scale. Whole-mount step-section pathology maps were used for imaging-pathologic analysis correlation. Receiver operating characteristic curves were constructed and areas under the curves (AUCs) were estimated nonparametrically for assessment of reader accuracy. At surgical-pathologic analysis, one (0.6%) patient had no cancer; 124 (78%) patients, organ-confined (stage pT2) disease; 29 (18%) patients, ECE (stage pT3a); two (1%) patients, SVI (stage pT3b); and two (1%) patients, bladder neck invasion (stage pT4). Forty-six (29%) patients had a total tumor volume of less than 0.5 cm(3). With combined MR imaging-MR spectroscopic imaging, the two readers achieved 80% accuracy in disease staging and AUCs of 0.62 and 0.71 for the prediction of clinically nonimportant cancer. Clinical stage T1c prostate cancers are heterogeneous in pathologic stage and volume. MR imaging may

  3. Sparse spectral deconvolution algorithm for noncartesian MR spectroscopic imaging.

    Bhave, Sampada; Eslami, Ramin; Jacob, Mathews

    2014-02-01

    To minimize line shape distortions and spectral leakage artifacts in MR spectroscopic imaging (MRSI). A spatially and spectrally regularized non-Cartesian MRSI algorithm that uses the line shape distortion priors, estimated from water reference data, to deconvolve the spectra is introduced. Sparse spectral regularization is used to minimize noise amplification associated with deconvolution. A spiral MRSI sequence that heavily oversamples the central k-space regions is used to acquire the MRSI data. The spatial regularization term uses the spatial supports of brain and extracranial fat regions to recover the metabolite spectra and nuisance signals at two different resolutions. Specifically, the nuisance signals are recovered at the maximum resolution to minimize spectral leakage, while the point spread functions of metabolites are controlled to obtain acceptable signal-to-noise ratio. The comparisons of the algorithm against Tikhonov regularized reconstructions demonstrates considerably reduced line-shape distortions and improved metabolite maps. The proposed sparsity constrained spectral deconvolution scheme is effective in minimizing the line-shape distortions. The dual resolution reconstruction scheme is capable of minimizing spectral leakage artifacts. Copyright © 2013 Wiley Periodicals, Inc.

  4. Electron spectroscopic imaging of antigens by reaction with boronated antibodies.

    Qualmann, B; Kessels, M M; Klobasa, F; Jungblut, P W; Sierralta, W D

    1996-07-01

    Two small homogeneous markers for electron spectroscopic imaging (ESI) containing eight dodecaborane cages linked to a poly-alpha, epsilon-L-lysine dendrimer were synthesized; one of these was made water soluble by the attachment of a polyether. The markers were coupled to the sulfhydryl group of (monovalent) antibody fragments (Fab') by a homobifunctional cross-linker. While the coupling ratios of the poorly water-soluble compound did not exceed 20%, the polyether-containing variant reacted quantitatively. Its suitability for immunolabelling was tested in a study of the mechanism of the transcellular transport of an administered heterologous protein (bovine serum albumin, BSA) through ileal enterocytes of newborn piglets by endocytotic vesicles in comparison to conventional immunogold reagents. The post-embedding technique was employed. The boronated Fab' gave rise to considerably higher tagging frequencies than seen with immunogold, as could be expected from its form- and size-related physical advantages and the dense packing of BSA in the vesicles. The new probe, carrying the antigen-combining cleft at one end and the boron clusters at the opposite end of the oval-shaped conjugate, add to the potential of ESI-based immunocytochemistry.

  5. Metabolic networks in epilepsy by MR spectroscopic imaging.

    Pan, J W; Spencer, D D; Kuzniecky, R; Duckrow, R B; Hetherington, H; Spencer, S S

    2012-12-01

    The concept of an epileptic network has long been suggested from both animal and human studies of epilepsy. Based on the common observation that the MR spectroscopic imaging measure of NAA/Cr is sensitive to neuronal function and injury, we use this parameter to assess for the presence of a metabolic network in mesial temporal lobe epilepsy (MTLE) patients. A multivariate factor analysis is performed with controls and MTLE patients, using NAA/Cr measures from 12 loci: the bilateral hippocampi, thalami, basal ganglia, and insula. The factor analysis determines which and to what extent these loci are metabolically covarying. We extract two independent factors that explain the data's variability in control and MTLE patients. In controls, these factors characterize a 'thalamic' and 'dominant subcortical' function. The MTLE patients also exhibit a 'thalamic' factor, in addition to a second factor involving the ipsilateral insula and bilateral basal ganglia. These data suggest that MTLE patients demonstrate a metabolic network that involves the thalami, also seen in controls. The MTLE patients also display a second set of metabolically covarying regions that may be a manifestation of the epileptic network that characterizes limbic seizure propagation. © 2012 John Wiley & Sons A/S.

  6. Phosphorus-31 spectroscopic imaging of the human liver

    Biran, M.; Raffard, G.; Canioni, P.; Kien, P.

    1993-01-01

    During the last decade, progresses in the field of nuclear magnetic resonance spectroscopy (M.R.S.), have allowed the metabolic studies of complex biological systems. Since the coming out of whole body magnets, clinical applications are possible; they utilize magnetic field gradients coupled with selective pulse sequences. Study of the phosphorylated metabolism of human liver can be performed with sequences as ISIS, FROGS or 1D-CSI. But they present some disadvantages (for instance contamination by phosphocreatine from muscle). In the present work, we have studied the human liver in vivo by 31 P spectroscopic imaging. Several spectra could be acquired with only one acquisition. This study has needed the building of radiofrequency coils (surface coils), specially designed for liver observation (15 cm diameter 31 P coil and 19 cm diameter proton coil, both transmitter and receiver coils). Preliminary studies have been done on a phantom followed by in vivo measurements on healthy subject livers. We have obtained localized 31 P N.M.R. spectra corresponding to different voxels within the hepatic tissue. The conditions of acquisition of spectra and the problems related to the saturation of phosphorylated metabolite signals (in particular phosphodiesters) are discussed. (author). 5 figs., 15 refs

  7. A Compressed Sensing-based Image Reconstruction Algorithm for Solar Flare X-Ray Observations

    Felix, Simon; Bolzern, Roman; Battaglia, Marina, E-mail: simon.felix@fhnw.ch, E-mail: roman.bolzern@fhnw.ch, E-mail: marina.battaglia@fhnw.ch [University of Applied Sciences and Arts Northwestern Switzerland FHNW, 5210 Windisch (Switzerland)

    2017-11-01

    One way of imaging X-ray emission from solar flares is to measure Fourier components of the spatial X-ray source distribution. We present a new compressed sensing-based algorithm named VIS-CS, which reconstructs the spatial distribution from such Fourier components. We demonstrate the application of the algorithm on synthetic and observed solar flare X-ray data from the Reuven Ramaty High Energy Solar Spectroscopic Imager satellite and compare its performance with existing algorithms. VIS-CS produces competitive results with accurate photometry and morphology, without requiring any algorithm- and X-ray-source-specific parameter tuning. Its robustness and performance make this algorithm ideally suited for the generation of quicklook images or large image cubes without user intervention, such as for imaging spectroscopy analysis.

  8. A Compressed Sensing-based Image Reconstruction Algorithm for Solar Flare X-Ray Observations

    Felix, Simon; Bolzern, Roman; Battaglia, Marina

    2017-11-01

    One way of imaging X-ray emission from solar flares is to measure Fourier components of the spatial X-ray source distribution. We present a new compressed sensing-based algorithm named VIS_CS, which reconstructs the spatial distribution from such Fourier components. We demonstrate the application of the algorithm on synthetic and observed solar flare X-ray data from the Reuven Ramaty High Energy Solar Spectroscopic Imager satellite and compare its performance with existing algorithms. VIS_CS produces competitive results with accurate photometry and morphology, without requiring any algorithm- and X-ray-source-specific parameter tuning. Its robustness and performance make this algorithm ideally suited for the generation of quicklook images or large image cubes without user intervention, such as for imaging spectroscopy analysis.

  9. Constraining reconnection region conditions using imaging and spectroscopic analysis of a coronal jet

    Brannon, Sean; Kankelborg, Charles

    2017-08-01

    Coronal jets typically appear as thin, collimated structures in EUV and X-ray wavelengths, and are understood to be initiated by magnetic reconnection in the lower corona or upper chromosphere. Plasma that is heated and accelerated upward into coronal jets may therefore carry indirect information on conditions in the reconnection region and current sheet located at the jet base. On 2017 October 14, the Interface Region Imaging Spectrograph (IRIS) and Solar Dynamics Observatory Atmospheric Imaging Assembly (SDO/AIA) observed a series of jet eruptions originating from NOAA AR 12599. The jet structure has a length-to-width ratio that exceeds 50, and remains remarkably straight throughout its evolution. Several times during the observation bright blobs of plasma are seen to erupt upward, ascending and subsequently descending along the structure. These blobs are cotemporal with footpoint and arcade brightenings, which we believe indicates multiple episodes of reconnection at the structure base. Through imaging and spectroscopic analysis of jet and footpoint plasma we determine a number of properties, including the line-of-sight inclination, the temperature and density structure, and lift-off velocities and accelerations of jet eruptions. We use these properties to constrain the geometry of the jet structure and conditions in reconnection region.

  10. Volumetric Spectroscopic Imaging of Glioblastoma Multiforme Radiation Treatment Volumes

    Parra, N. Andres [Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida (United States); Maudsley, Andrew A. [Department of Radiology, University of Miami Miller School of Medicine, Miami, Florida (United States); Gupta, Rakesh K. [Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, Haryana (India); Ishkanian, Fazilat; Huang, Kris [Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida (United States); Walker, Gail R. [Biostatistics and Bioinformatics Core Resource, Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, Florida (United States); Padgett, Kyle [Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida (United States); Department of Radiology, University of Miami Miller School of Medicine, Miami, Florida (United States); Roy, Bhaswati [Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, Haryana (India); Panoff, Joseph; Markoe, Arnold [Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida (United States); Stoyanova, Radka, E-mail: RStoyanova@med.miami.edu [Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida (United States)

    2014-10-01

    Purpose: Magnetic resonance (MR) imaging and computed tomography (CT) are used almost exclusively in radiation therapy planning of glioblastoma multiforme (GBM), despite their well-recognized limitations. MR spectroscopic imaging (MRSI) can identify biochemical patterns associated with normal brain and tumor, predominantly by observation of choline (Cho) and N-acetylaspartate (NAA) distributions. In this study, volumetric 3-dimensional MRSI was used to map these compounds over a wide region of the brain and to evaluate metabolite-defined treatment targets (metabolic tumor volumes [MTV]). Methods and Materials: Volumetric MRSI with effective voxel size of ∼1.0 mL and standard clinical MR images were obtained from 19 GBM patients. Gross tumor volumes and edema were manually outlined, and clinical target volumes (CTVs) receiving 46 and 60 Gy were defined (CTV{sub 46} and CTV{sub 60}, respectively). MTV{sub Cho} and MTV{sub NAA} were constructed based on volumes with high Cho and low NAA relative to values estimated from normal-appearing tissue. Results: The MRSI coverage of the brain was between 70% and 76%. The MTV{sub NAA} were almost entirely contained within the edema, and the correlation between the 2 volumes was significant (r=0.68, P=.001). In contrast, a considerable fraction of MTV{sub Cho} was outside of the edema (median, 33%) and for some patients it was also outside of the CTV{sub 46} and CTV{sub 60}. These untreated volumes were greater than 10% for 7 patients (37%) in the study, and on average more than one-third (34.3%) of the MTV{sub Cho} for these patients were outside of CTV{sub 60}. Conclusions: This study demonstrates the potential usefulness of whole-brain MRSI for radiation therapy planning of GBM and revealed that areas of metabolically active tumor are not covered by standard RT volumes. The described integration of MTV into the RT system will pave the way to future clinical trials investigating outcomes in patients treated based on

  11. Undersampling strategies for compressed sensing accelerated MR spectroscopic imaging

    Vidya Shankar, Rohini; Hu, Houchun Harry; Bikkamane Jayadev, Nutandev; Chang, John C.; Kodibagkar, Vikram D.

    2017-03-01

    Compressed sensing (CS) can accelerate magnetic resonance spectroscopic imaging (MRSI), facilitating its widespread clinical integration. The objective of this study was to assess the effect of different undersampling strategy on CS-MRSI reconstruction quality. Phantom data were acquired on a Philips 3 T Ingenia scanner. Four types of undersampling masks, corresponding to each strategy, namely, low resolution, variable density, iterative design, and a priori were simulated in Matlab and retrospectively applied to the test 1X MRSI data to generate undersampled datasets corresponding to the 2X - 5X, and 7X accelerations for each type of mask. Reconstruction parameters were kept the same in each case(all masks and accelerations) to ensure that any resulting differences can be attributed to the type of mask being employed. The reconstructed datasets from each mask were statistically compared with the reference 1X, and assessed using metrics like the root mean square error and metabolite ratios. Simulation results indicate that both the a priori and variable density undersampling masks maintain high fidelity with the 1X up to five-fold acceleration. The low resolution mask based reconstructions showed statistically significant differences from the 1X with the reconstruction failing at 3X, while the iterative design reconstructions maintained fidelity with the 1X till 4X acceleration. In summary, a pilot study was conducted to identify an optimal sampling mask in CS-MRSI. Simulation results demonstrate that the a priori and variable density masks can provide statistically similar results to the fully sampled reference. Future work would involve implementing these two masks prospectively on a clinical scanner.

  12. Evaluation of spectroscopic modeling for iron ions and study on non-equilibrium ionization phenomena for solar and LHD plasmas

    Watanabe, Tetsuya; Hara, Hirohisa; Yamamoto, Norimasa; Kato, Daiji; Sakaue, Hiroyuki A.; Murakami, Izumi

    2013-01-01

    Spectroscopic observations of EUV emission lines in the transition region (TR) and the corona provide unique information on physical conditions in the outer atmosphere of the Sun. The EUV Imaging Spectrometer (EIS) on board the Hinode satellite is capable of observing, for the first time in EUV, spectra and monochromatic images of plasmas in the solar TR and corona; these plasmas could possibly be in non-ionization-equilibrium conditions. EIS observes over two-wavelength bands of 170 - 210 Å and 250 - 290 Å, with typical time-resolutions of 1 - 10 seconds. Iron line emissions emerging from these wavelengths reveal that dynamic plasma accelerations and heating take place in the solar atmosphere. On the other hand, the tracer-encapsulated-pellet (TESPEL) experiments provide spectral information of EUV emission lines from iron ions produced in the Large Helical Device (LHD). Relatively cool plasmas with electron temperatures similar to those of the solar corona can be generated by controlling the neutral beam injector (NBI) system. A time-dependent collisional radiative (CR) model for elemental iron is developed as a common tool to diagnose temperatures and densities of those plasmas in the Sun and in LHD; no systematic model yet exists for iron ions in the L- and M-shell ionization stages, which are very important for coronal plasma diagnostics. Adopting the best available theoretical calculations, as well as generating the experimental data, we improve the atomic parameters of highly charged iron ions, and these results are used to extract more accurate diagnostic information out of the EIS spectra. (author)

  13. Solar Flare Dynamic Microwave Imaging with EOVSA

    Gary, D. E.; Chen, B.; Nita, G. M.; Fleishman, G. D.; Yu, S.; White, S. M.; Hurford, G. J.; McTiernan, J. M.

    2017-12-01

    The Expanded Owens Valley Solar Array (EOVSA) is both an expansion of our existing solar array and serves as a prototype for a much larger future project, the Frequency Agile Solar Radiotelescope (FASR). EOVSA is now complete, and is producing daily imaging of the full solar disk, including active regions and solar radio bursts at hundreds of frequencies in the range 2.8-18 GHz. We present highlights of the 1-s-cadence dynamic imaging spectroscropy of radio bursts we have obtained to date, along with deeper analysis of multi-wavelength observations and modeling of a well-observed burst. These observations are revealing the full life-cycle of the trapped population of high-energy electrons, from their initial acceleration and subsequent energy-evolution to their eventual decay through escape and thermalization. All of our data are being made available for download in both quick-look image form and in the form of the community-standard CASA measurement sets for subsequent imaging and analysis.

  14. Bio-medical X-ray imaging with spectroscopic pixel detectors

    Butler, A P H; Tipples, R; Cook, N; Watts, R; Meyer, J; Bell, A J; Melzer, T R; Butler, P H

    2008-01-01

    The aim of this study is to review the clinical potential of spectroscopic X-ray detectors and to undertake a feasibility study using a novel detector in a clinical hospital setting. Detectors currently in development, such as Medipix-3, will have multiple energy thresholds allowing for routine use of spectroscopic bio-medical imaging. We have coined the term MARS (Medipix All Resolution System) for bio-medical images that provide spatial, temporal, and energy information. The full clinical significance of spectroscopic X-ray imaging is difficult to predict but insights can be gained by examining both image reconstruction artifacts and the current uses of dual-energy techniques. This paper reviews the known uses of energy information in vascular imaging and mammography, clinically important fields. It then presents initial results from using Medipix-2, to image human tissues within a clinical radiology department. Detectors currently in development, such as Medipix-3, will have multiple energy thresholds allo...

  15. Single-shot magnetic resonance spectroscopic imaging with partial parallel imaging.

    Posse, Stefan; Otazo, Ricardo; Tsai, Shang-Yueh; Yoshimoto, Akio Ernesto; Lin, Fa-Hsuan

    2009-03-01

    A magnetic resonance spectroscopic imaging (MRSI) pulse sequence based on proton-echo-planar-spectroscopic-imaging (PEPSI) is introduced that measures two-dimensional metabolite maps in a single excitation. Echo-planar spatial-spectral encoding was combined with interleaved phase encoding and parallel imaging using SENSE to reconstruct absorption mode spectra. The symmetrical k-space trajectory compensates phase errors due to convolution of spatial and spectral encoding. Single-shot MRSI at short TE was evaluated in phantoms and in vivo on a 3-T whole-body scanner equipped with a 12-channel array coil. Four-step interleaved phase encoding and fourfold SENSE acceleration were used to encode a 16 x 16 spatial matrix with a 390-Hz spectral width. Comparison with conventional PEPSI and PEPSI with fourfold SENSE acceleration demonstrated comparable sensitivity per unit time when taking into account g-factor-related noise increases and differences in sampling efficiency. LCModel fitting enabled quantification of inositol, choline, creatine, and N-acetyl-aspartate (NAA) in vivo with concentration values in the ranges measured with conventional PEPSI and SENSE-accelerated PEPSI. Cramer-Rao lower bounds were comparable to those obtained with conventional SENSE-accelerated PEPSI at the same voxel size and measurement time. This single-shot MRSI method is therefore suitable for applications that require high temporal resolution to monitor temporal dynamics or to reduce sensitivity to tissue movement.

  16. High grade gilomas and solitary metastases: differentiation using perfusion MR imaging and spectroscopic MR imaging

    Law, M.; Cha, S.; Knopp, E.A.; Johnson, G.; Litt, A.W.

    2002-01-01

    Full text: To determine whether perfusion MRI (pMRI) and spectroscopic MR imaging (sMRI) can be used to differentiate high grade primary gliomas and solitary metastases on the basis of differences in vascularity and metabolite levels in the peritumoral. Fifty-one patients with a solitary brain tumor (33 gliomas, 18 metastases) underwent conventional MRI, contrast enhanced pMRI and sMRI before surgical resection or stereotactic biopsy. The peri-tumoral region is defined as the area within the white matter, immediately adjacent to the enhancing portion of the tumor (hyperintense on T2- weighted imaging but no enhancement on post-contrast T1-weighted imaging). Relative cerebral blood volume (rCBV) measurements were made in these regions from the pMRI data. Spectra from the enhancing tumor, the peritumoral region and normal brain, were obtained from the 2D multi-voxel CSI acquisition (TE = 135ms). The measured rCBV within the abnormal peritumoral region in highgrade gliomas and metastasis were 1.31 ± 0.97 (mean ± standard deviation) and 0.39 ± 0.19, respectively. The difference was statistically significant (p<0.0001). Spectroscopic imaging demonstrated elevated choline (Cho/Cr 2.28 ± 1.24) in the peritumoral region of gliomas but not in metastasis (Cho/Cr = 0.76 ± 0.23). The difference was again statistically significant (p 0.001), with Student's t-test. Although conventional imaging characteristics of solitary metastases and primary high grade gliomas may sometimes be similar, pMRI and sMRI are able to distinguish between the two, based on the rCBV and metabolite ratios within the peri-tumoral region. Copyright (2002) Blackwell Science Pty Ltd

  17. The first X-ray imaging spectroscopy of quiescent solar active regions with NuSTAR

    Hannah, Iain G.; Grefenstette, Brian W.; Smith, David M.

    2016-01-01

    We present the first observations of quiescent active regions (ARs) using the Nuclear Spectroscopic Telescope Array (NuSTAR), a focusing hard X-ray telescope capable of studying faint solar emission from high-temperature and non-thermal sources. We analyze the first directly imaged and spectrally...... resolved X-rays above 2 keV from non-flaring ARs, observed near the west limb on 2014 November 1. The NuSTAR X-ray images match bright features seen in extreme ultraviolet and soft X-rays. The NuSTAR imaging spectroscopy is consistent with isothermal emission of temperatures 3.1-4.4 MK and emission...

  18. SDSS-III: Massive Spectroscopic Surveys of the Distant Universe, the Milky Way, and Extra-Solar Planetary Systems

    Eisenstein, Daniel J.; Weinberg, David H.; Agol, Eric; Aihara, Hiroaki; Allende Prieto, Carlos; Anderson, Scott F.; Arns, James A.; Aubourg, Éric; Bailey, Stephen; Balbinot, Eduardo; Barkhouser, Robert; Beers, Timothy C.; Berlind, Andreas A.; Bickerton, Steven J.; Bizyaev, Dmitry; Blanton, Michael R.; Bochanski, John J.; Bolton, Adam S.; Bosman, Casey T.; Bovy, Jo; Brandt, W. N.; Breslauer, Ben; Brewington, Howard J.; Brinkmann, J.; Brown, Peter J.; Brownstein, Joel R.; Burger, Dan; Busca, Nicolas G.; Campbell, Heather; Cargile, Phillip A.; Carithers, William C.; Carlberg, Joleen K.; Carr, Michael A.; Chang, Liang; Chen, Yanmei; Chiappini, Cristina; Comparat, Johan; Connolly, Natalia; Cortes, Marina; Croft, Rupert A. C.; Cunha, Katia; da Costa, Luiz N.; Davenport, James R. A.; Dawson, Kyle; De Lee, Nathan; Porto de Mello, Gustavo F.; de Simoni, Fernando; Dean, Janice; Dhital, Saurav; Ealet, Anne; Ebelke, Garrett L.; Edmondson, Edward M.; Eiting, Jacob M.; Escoffier, Stephanie; Esposito, Massimiliano; Evans, Michael L.; Fan, Xiaohui; Femenía Castellá, Bruno; Dutra Ferreira, Leticia; Fitzgerald, Greg; Fleming, Scott W.; Font-Ribera, Andreu; Ford, Eric B.; Frinchaboy, Peter M.; García Pérez, Ana Elia; Gaudi, B. Scott; Ge, Jian; Ghezzi, Luan; Gillespie, Bruce A.; Gilmore, G.; Girardi, Léo; Gott, J. Richard; Gould, Andrew; Grebel, Eva K.; Gunn, James E.; Hamilton, Jean-Christophe; Harding, Paul; Harris, David W.; Hawley, Suzanne L.; Hearty, Frederick R.; Hennawi, Joseph F.; González Hernández, Jonay I.; Ho, Shirley; Hogg, David W.; Holtzman, Jon A.; Honscheid, Klaus; Inada, Naohisa; Ivans, Inese I.; Jiang, Linhua; Jiang, Peng; Johnson, Jennifer A.; Jordan, Cathy; Jordan, Wendell P.; Kauffmann, Guinevere; Kazin, Eyal; Kirkby, David; Klaene, Mark A.; Knapp, G. R.; Kneib, Jean-Paul; Kochanek, C. S.; Koesterke, Lars; Kollmeier, Juna A.; Kron, Richard G.; Lampeitl, Hubert; Lang, Dustin; Lawler, James E.; Le Goff, Jean-Marc; Lee, Brian L.; Lee, Young Sun; Leisenring, Jarron M.; Lin, Yen-Ting; Liu, Jian; Long, Daniel C.; Loomis, Craig P.; Lucatello, Sara; Lundgren, Britt; Lupton, Robert H.; Ma, Bo; Ma, Zhibo; MacDonald, Nicholas; Mack, Claude; Mahadevan, Suvrath; Maia, Marcio A. G.; Majewski, Steven R.; Makler, Martin; Malanushenko, Elena; Malanushenko, Viktor; Mandelbaum, Rachel; Maraston, Claudia; Margala, Daniel; Maseman, Paul; Masters, Karen L.; McBride, Cameron K.; McDonald, Patrick; McGreer, Ian D.; McMahon, Richard G.; Mena Requejo, Olga; Ménard, Brice; Miralda-Escudé, Jordi; Morrison, Heather L.; Mullally, Fergal; Muna, Demitri; Murayama, Hitoshi; Myers, Adam D.; Naugle, Tracy; Neto, Angelo Fausti; Nguyen, Duy Cuong; Nichol, Robert C.; Nidever, David L.; O'Connell, Robert W.; Ogando, Ricardo L. C.; Olmstead, Matthew D.; Oravetz, Daniel J.; Padmanabhan, Nikhil; Paegert, Martin; Palanque-Delabrouille, Nathalie; Pan, Kaike; Pandey, Parul; Parejko, John K.; Pâris, Isabelle; Pellegrini, Paulo; Pepper, Joshua; Percival, Will J.; Petitjean, Patrick; Pfaffenberger, Robert; Pforr, Janine; Phleps, Stefanie; Pichon, Christophe; Pieri, Matthew M.; Prada, Francisco; Price-Whelan, Adrian M.; Raddick, M. Jordan; Ramos, Beatriz H. F.; Reid, I. Neill; Reyle, Celine; Rich, James; Richards, Gordon T.; Rieke, George H.; Rieke, Marcia J.; Rix, Hans-Walter; Robin, Annie C.; Rocha-Pinto, Helio J.; Rockosi, Constance M.; Roe, Natalie A.; Rollinde, Emmanuel; Ross, Ashley J.; Ross, Nicholas P.; Rossetto, Bruno; Sánchez, Ariel G.; Santiago, Basilio; Sayres, Conor; Schiavon, Ricardo; Schlegel, David J.; Schlesinger, Katharine J.; Schmidt, Sarah J.; Schneider, Donald P.; Sellgren, Kris; Shelden, Alaina; Sheldon, Erin; Shetrone, Matthew; Shu, Yiping; Silverman, John D.; Simmerer, Jennifer; Simmons, Audrey E.; Sivarani, Thirupathi; Skrutskie, M. F.; Slosar, Anže; Smee, Stephen; Smith, Verne V.; Snedden, Stephanie A.; Stassun, Keivan G.; Steele, Oliver; Steinmetz, Matthias; Stockett, Mark H.; Stollberg, Todd; Strauss, Michael A.; Szalay, Alexander S.; Tanaka, Masayuki; Thakar, Aniruddha R.; Thomas, Daniel; Tinker, Jeremy L.; Tofflemire, Benjamin M.; Tojeiro, Rita; Tremonti, Christy A.; Vargas Magaña, Mariana; Verde, Licia; Vogt, Nicole P.; Wake, David A.; Wan, Xiaoke; Wang, Ji; Weaver, Benjamin A.; White, Martin; White, Simon D. M.; Wilson, John C.; Wisniewski, John P.; Wood-Vasey, W. Michael; Yanny, Brian; Yasuda, Naoki; Yèche, Christophe; York, Donald G.; Young, Erick; Zasowski, Gail; Zehavi, Idit; Zhao, Bo

    2011-09-01

    Building on the legacy of the Sloan Digital Sky Survey (SDSS-I and II), SDSS-III is a program of four spectroscopic surveys on three scientific themes: dark energy and cosmological parameters, the history and structure of the Milky Way, and the population of giant planets around other stars. In keeping with SDSS tradition, SDSS-III will provide regular public releases of all its data, beginning with SDSS Data Release 8 (DR8), which was made public in 2011 January and includes SDSS-I and SDSS-II images and spectra reprocessed with the latest pipelines and calibrations produced for the SDSS-III investigations. This paper presents an overview of the four surveys that comprise SDSS-III. The Baryon Oscillation Spectroscopic Survey will measure redshifts of 1.5 million massive galaxies and Lyα forest spectra of 150,000 quasars, using the baryon acoustic oscillation feature of large-scale structure to obtain percent-level determinations of the distance scale and Hubble expansion rate at z R = λ/Δλ ≈ 1800) optical spectra of 118,000 stars in a variety of target categories, probing chemical evolution, stellar kinematics and substructure, and the mass profile of the dark matter halo from the solar neighborhood to distances of 100 kpc. APOGEE, the Apache Point Observatory Galactic Evolution Experiment, will obtain high-resolution (R ≈ 30,000), high signal-to-noise ratio (S/N >= 100 per resolution element), H-band (1.51 μm data set for understanding the formation and dynamical evolution of giant planet systems. As of 2011 January, SDSS-III has obtained spectra of more than 240,000 galaxies, 29,000 z >= 2.2 quasars, and 140,000 stars, including 74,000 velocity measurements of 2580 stars for MARVELS.

  19. Spectroscopic Diagnostics of Solar Magnetic Flux Ropes Using Iron Forbidden Line

    Cheng, X.; Ding, M. D.

    2016-01-01

    In this Letter, we present Interface Region Imaging Spectrograph Fe XXI 1354.08 A forbidden line emission of two magnetic flux ropes (MFRs) that caused two fast coronal mass ejections with velocities of $\\ge$1000 km s$^{-1}$ and strong flares (X1.6 and M6.5) on 2014 September 10 and 2015 June 22, respectively. The EUV images at the 131 A and 94 A passbands provided by the Atmospheric Imaging Assembly on board Solar Dynamics Observatory reveal that both MFRs initially appear as suspended hot c...

  20. Initial experience of 3 tesla endorectal coil magnetic resonance imaging and 1H-spectroscopic imaging of the prostate.

    Fütterer, J.J.; Scheenen, T.W.J.; Huisman, H.J.; Klomp, D.W.J.; Dorsten, F.A. van; Hulsbergen-van de Kaa, C.A.; Witjes, J.A.; Heerschap, A.; Barentsz, J.O.

    2004-01-01

    RATIONALE AND OBJECTIVES: We sought to explore the feasibility of magnetic resonance imaging (MRI) of the prostate at 3T, with the knowledge of potential drawbacks of MRI at high field strengths. MATERIAL AND METHOD: MRI, dynamic MRI, and 1H-MR spectroscopic imaging were performed in 10 patients

  1. Review of Image Quality Measures for Solar Imaging

    Popowicz, Adam; Radlak, Krystian; Bernacki, Krzysztof; Orlov, Valeri

    2017-12-01

    Observations of the solar photosphere from the ground encounter significant problems caused by Earth's turbulent atmosphere. Before image reconstruction techniques can be applied, the frames obtained in the most favorable atmospheric conditions (the so-called lucky frames) have to be carefully selected. However, estimating the quality of images containing complex photospheric structures is not a trivial task, and the standard routines applied in nighttime lucky imaging observations are not applicable. In this paper we evaluate 36 methods dedicated to the assessment of image quality, which were presented in the literature over the past 40 years. We compare their effectiveness on simulated solar observations of both active regions and granulation patches, using reference data obtained by the Solar Optical Telescope on the Hinode satellite. To create images that are affected by a known degree of atmospheric degradation, we employed the random wave vector method, which faithfully models all the seeing characteristics. The results provide useful information about the method performances, depending on the average seeing conditions expressed by the ratio of the telescope's aperture to the Fried parameter, D/r0. The comparison identifies three methods for consideration by observers: Helmli and Scherer's mean, the median filter gradient similarity, and the discrete cosine transform energy ratio. While the first method requires less computational effort and can be used effectively in virtually any atmospheric conditions, the second method shows its superiority at good seeing (D/r0<4). The third method should mainly be considered for the post-processing of strongly blurred images.

  2. Accelerated gradient methods for the x-ray imaging of solar flares

    Bonettini, S.; Prato, M.

    2014-05-01

    In this paper we present new optimization strategies for the reconstruction of x-ray images of solar flares by means of the data collected by the Reuven Ramaty high energy solar spectroscopic imager. The imaging concept of the satellite is based on rotating modulation collimator instruments, which allow the use of both Fourier imaging approaches and reconstruction techniques based on the straightforward inversion of the modulated count profiles. Although in the last decade, greater attention has been devoted to the former strategies due to their very limited computational cost, here we consider the latter model and investigate the effectiveness of different accelerated gradient methods for the solution of the corresponding constrained minimization problem. Moreover, regularization is introduced through either an early stopping of the iterative procedure, or a Tikhonov term added to the discrepancy function by means of a discrepancy principle accounting for the Poisson nature of the noise affecting the data.

  3. Near-infrared spectroscopic tissue imaging for medical applications

    Demos, Stavros [Livermore, CA; Staggs, Michael C [Tracy, CA

    2006-12-12

    Near infrared imaging using elastic light scattering and tissue autofluorescence are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

  4. Toward Spectroscopically Detecting the Global Latitudinal Temperature Variation on the Solar Surface

    Takeda, Y.; UeNo, S.

    2017-09-01

    A very slight rotation-induced latitudinal temperature variation (presumably on the order of several kelvin) on the solar surface is theoretically expected. While recent high-precision solar brightness observations reported its detection, confirmation by an alternative approach using the strengths of spectral lines is desirable, for which reducing the noise due to random fluctuation caused by atmospheric inhomogeneity is critical. Toward this difficult task, we carried out a pilot study of spectroscopically investigating the relative variation of temperature (T) at a number of points in the solar circumference region near to the limb (where latitude dependence should be detectable, if any exists) based on the equivalent widths (W) of 28 selected lines in the 5367 - 5393 Å and 6075 - 6100 Å regions. We paid special attention to i) clarifying which types of lines should be employed and ii) how much precision is attainable in practice. We found that lines with strong T-sensitivity (|log W/log T|) should be used and that very weak lines should be avoided because they inevitably suffer strong relative fluctuations (Δ W/W). Our analysis revealed that a precision of Δ T/T ≈ 0.003 (corresponding to ≈ 15 K) can be achieved at best by a spectral line with comparatively large |log W/log T|, although this can possibly be further improved When a number of lines are used all together. Accordingly, if many such favorable lines could be measured with subpercent precision of Δ W/W and by averaging the resulting Δ T/T from each line, the random noise would eventually be reduced to ≲ 1 K and detection of a very subtle amount of global T-gradient might be possible.

  5. JHelioviewer: Exploring Petabytes of Solar Images

    Mueller, Daniel; Fleck, Bernhard; Dimitoglou, George; Garcia Ortiz, Juan Pablo; Schmidt, Ludwig; Hughitt, Keith; Ireland, Jack

    Space missions generate an ever-growing amount of data, as impressively highlighted by the Solar Dynamics Observatory's (SDO) expected return of 1.4 TByte/day. In order to fully ex-ploit their data, scientists need to be able to browse and visualize many different data products spanning a large range of physical length and time scales. So far, the tools available to the scientific community either require downloading all potentially relevant data sets beforehand in their entirety or provide only movies with a fixed resolution and cadence. For SDO, the former approach is prohibitive due to the shear data volume, while the latter does not do justice to the high resolution and cadence of the images. To address this challenge, we have developed JHelioviewer, a JPEG 2000-based visualization and discovery software for solar image data. JHelioviewer makes the vast amount of SDO images available to the worldwide community, lets users browse more than 14 years worth of images from the Solar and Heliospheric Observatory (SOHO) and facilitates browsing and analysis of complex time-dependent data sets from mul-tiple sources in general. The user interface for JHelioviewer is a multi-platform Java client that communicates with a remote server via the JPEG 2000 interactive protocol JPIP. The random code stream access of JPIP minimizes data transfer and can encapsulate metadata as well as multiple image channels in one data stream. This presentation will illustrate the features of JHelioviewer and highlight the advantages of JPEG 2000 as a new data compression standard.

  6. Raman Spectroscopic Imaging of the Whole Ciona intestinalis Embryo during Development

    Nakamura, Mitsuru J.; Hotta, Kohji; Oka, Kotaro

    2013-01-01

    Intracellular composition and the distribution of bio-molecules play central roles in the specification of cell fates and morphogenesis during embryogenesis. Consequently, investigation of changes in the expression and distribution of bio-molecules, especially mRNAs and proteins, is an important challenge in developmental biology. Raman spectroscopic imaging, a non-invasive and label-free technique, allows simultaneous imaging of the intracellular composition and distribution of multiple bio-molecules. In this study, we explored the application of Raman spectroscopic imaging in the whole Ciona intestinalis embryo during development. Analysis of Raman spectra scattered from C. intestinalis embryos revealed a number of localized patterns of high Raman intensity within the embryo. Based on the observed distribution of bio-molecules, we succeeded in identifying the location and structure of differentiated muscle and endoderm within the whole embryo, up to the tailbud stage, in a label-free manner. Furthermore, during cell differentiation, we detected significant differences in cell state between muscle/endoderm daughter cells and daughter cells with other fates that had divided from the same mother cells; this was achieved by focusing on the Raman intensity of single Raman bands at 1002 or 1526 cm−1, respectively. This study reports the first application of Raman spectroscopic imaging to the study of identifying and characterizing differentiating tissues in a whole chordate embryo. Our results suggest that Raman spectroscopic imaging is a feasible label-free technique for investigating the developmental process of the whole embryo of C. intestinalis. PMID:23977129

  7. How spectroscopic x-ray imaging benefits from inter-pixel communication

    Koenig, Thomas; Hamann, Elias; Cecilia, Angelica; Ballabriga, Rafael; Campbell, Michael; Ruat, Marie; Tlustos, Lukas; Fauler, Alex; Fiederle, Michael; Baumbach, Tilo

    2014-01-01

    Spectroscopic x-ray imaging based on pixellated semiconductor detectors can be sensitive to charge sharing and K-fluorescence, depending on the sensor material used, its thickness and the pixel pitch employed. As a consequence, spectroscopic resolution is partially lost. In this paper, we study a new detector ASIC, the Medipix3RX, that offers a novel feature called charge summing, which is established by making adjacent pixels communicate with each other. Consequently, single photon interactions resulting in multiple hits are almost completely avoided. We investigate this charge summing mode with respect to those of its imaging properties that are of interest in medical physics and benchmark them against the case without charge summing. In particular, we review its influence on spectroscopic resolution and find that the low energy bias normally present when recording energy spectra is dramatically reduced. Furthermore, we show that charge summing provides a modulation transfer function which is almost indepen...

  8. Three dimensional nuclear magnetic resonance spectroscopic imaging of sodium ions using stochastic excitation and oscillating gradients

    Frederick, B.deB.

    1994-12-01

    Nuclear magnetic resonance (NMR) spectroscopic imaging of 23 Na holds promise as a non-invasive method of mapping Na + distributions, and for differentiating pools of Na + ions in biological tissues. However, due to NMR relaxation properties of 23 Na in vivo, a large fraction of Na + is not visible with conventional NMR imaging methods. An alternate imaging method, based on stochastic excitation and oscillating gradients, has been developed which is well adapted to measuring nuclei with short T 2 . Contemporary NMR imaging techniques have dead times of up to several hundred microseconds between excitation and sampling, comparable to the shortest in vivo 23 Na T 2 values, causing significant signal loss. An imaging strategy based on stochastic excitation has been developed which greatly reduces experiment dead time by reducing peak radiofrequency (RF) excitation power and using a novel RF circuit to speed probe recovery. Continuously oscillating gradients are used to eliminate transient eddy currents. Stochastic 1 H and 23 Na spectroscopic imaging experiments have been performed on a small animal system with dead times as low as 25μs, permitting spectroscopic imaging with 100% visibility in vivo. As an additional benefit, the encoding time for a 32x32x32 spectroscopic image is under 30 seconds. The development and analysis of stochastic NMR imaging has been hampered by limitations of the existing phase demodulation reconstruction technique. Three dimensional imaging was impractical due to reconstruction time, and design and analysis of proposed experiments was limited by the mathematical intractability of the reconstruction method. A new reconstruction method for stochastic NMR based on Fourier interpolation has been formulated combining the advantage of a several hundredfold reduction in reconstruction time with a straightforward mathematical form

  9. Guided filtering for solar image/video processing

    Long Xu

    2017-06-01

    Full Text Available A new image enhancement algorithm employing guided filtering is proposed in this work for enhancement of solar images and videos, so that users can easily figure out important fine structures imbedded in the recorded images/movies for solar observation. The proposed algorithm can efficiently remove image noises, including Gaussian and impulse noises. Meanwhile, it can further highlight fibrous structures on/beyond the solar disk. These fibrous structures can clearly demonstrate the progress of solar flare, prominence coronal mass emission, magnetic field, and so on. The experimental results prove that the proposed algorithm gives significant enhancement of visual quality of solar images beyond original input and several classical image enhancement algorithms, thus facilitating easier determination of interesting solar burst activities from recorded images/movies.

  10. Correlated topographic and spectroscopic imaging by combined atomic force microscopy and optical microscopy

    Hu Dehong; Micic, Miodrag; Klymyshyn, Nicholas; Suh, Y.D.; Lu, H.P.

    2004-01-01

    Near-field scanning microscopy is a powerful approach to obtain topographic and spectroscopic characterization simultaneously for imaging biological and nanoscale systems. To achieve optical imaging at high spatial resolution beyond the diffraction limit, aperture-less metallic scanning tips have been utilized to enhance the laser illumination local electromagnetic field at the apex of the scanning tips. In this paper, we discuss and review our work on combined fluorescence imaging with AFM-metallic tip enhancement, finite element method simulation of the tip enhancement, and their applications on AFM-tip enhanced fluorescence lifetime imaging (AFM-FLIM) and correlated AFM and FLIM imaging of the living cells

  11. Spectroscopic magnetic resonance imaging of a tumefactive demyelinating lesion

    Law, M.; Meltzer, D.E.; Cha, S. [MRI Department, Department of Radiology, New York University Medical Center, Schwartz Building, Basement HCC, 530 First Avenue, New York, NY 10016 (United States)

    2002-12-01

    Tumefactive demyelinating lesions can present with features similar, clinically and radiologically, to those of brain tumours. Proton MR spectroscopy has been increasingly used to characterize intracranial pathology. As the underlying pathophysiology of neoplasms is different from that of demyelinating disease, one may expect the metabolic composition of neoplasms to be significantly different from that of demyelinating lesions. We report a 49-year-old woman in whom the neurologic and radiologic findings were highly suggestive of a high-grade brain tumor, and the spectroscopic features were sufficiently similar to that of a tumor to convince the neurosurgeon to operate. This case emphasizes the need for caution when confronted with a patient who presents with a differential diagnosis of demyelinating lesion versus neoplasm. (orig.)

  12. Metabolite ratios in 1H MR spectroscopic imaging of the prostate

    Kobus, T.; Wright, A.J.; Weiland, E.; Heerschap, A.; Scheenen, T.W.J.

    2015-01-01

    In (1)H MR spectroscopic imaging ((1)H-MRSI) of the prostate the spatial distribution of the signal levels of the metabolites choline, creatine, polyamines, and citrate are assessed. The ratio of choline (plus spermine as the main polyamine) plus creatine over citrate [(Cho+(Spm+)Cr)/Cit] is derived

  13. Fiber optic spectroscopic digital imaging sensor and method for flame properties monitoring

    Zelepouga, Serguei A [Hoffman Estates, IL; Rue, David M [Chicago, IL; Saveliev, Alexei V [Chicago, IL

    2011-03-15

    A system for real-time monitoring of flame properties in combustors and gasifiers which includes an imaging fiber optic bundle having a light receiving end and a light output end and a spectroscopic imaging system operably connected with the light output end of the imaging fiber optic bundle. Focusing of the light received by the light receiving end of the imaging fiber optic bundle by a wall disposed between the light receiving end of the fiber optic bundle and a light source, which wall forms a pinhole opening aligned with the light receiving end.

  14. Spectroscopic imaging technologies for online food safety and sanitation inspection

    The Environmental Microbial and Food Safety Laboratory, ARS, USDA is one of the leading groups for the development of optoelectronic sensing technologies and methodologies for food quality, safety, and sanitation inspection. High throughput hyperspectral and multispectral imaging techniques use Ram...

  15. The ExtraSolar Planetary Imaging Coronagraph

    Clampin, M.; Lyon, R.

    2010-10-01

    The Extrasolar Planetary Imaging Coronagraph (EPIC) is a 1.65-m telescope employing a visible nulling coronagraph (VNC) to deliver high-contrast images of extrasolar system architectures. EPIC will survey the architectures of exosolar systems, and investigate the physical nature of planets in these solar systems. EPIC will employ a Visible Nulling Coronagraph (VNC), featuring an inner working angle of ≤2λ/D, and offers the ideal balance between performance and feasibility of implementation, while not sacrificing science return. The VNC does not demand unrealistic thermal stability from its telescope optics, achieving its primary mirror surface figure requires no new technology, and pointing stability is within state of the art. The EPIC mission will be launched into a drift-away orbit with a five-year mission lifetime.

  16. MOSS spectroscopic camera for imaging time resolved plasma species temperature and flow speed

    Michael, Clive; Howard, John

    2000-01-01

    A MOSS (Modulated Optical Solid-State) spectroscopic camera has been devised to monitor the spatial and temporal variations of temperatures and flow speeds of plasma ion species, the Doppler broadening measurement being made of spectroscopic lines specified. As opposed to a single channel MOSS spectrometer, the camera images light from plasma onto an array of light detectors, being mentioned 2D imaging of plasma ion temperatures and flow speeds. In addition, compared to a conventional grating spectrometer, the MOSS camera shows an excellent light collecting performance which leads to the improvement of signal to noise ratio and of time resolution. The present paper first describes basic items of MOSS spectroscopy, then follows MOSS camera with an emphasis on the optical system of 2D imaging. (author)

  17. MOSS spectroscopic camera for imaging time resolved plasma species temperature and flow speed

    Michael, Clive; Howard, John [Australian National Univ., Plasma Research Laboratory, Canberra (Australia)

    2000-03-01

    A MOSS (Modulated Optical Solid-State) spectroscopic camera has been devised to monitor the spatial and temporal variations of temperatures and flow speeds of plasma ion species, the Doppler broadening measurement being made of spectroscopic lines specified. As opposed to a single channel MOSS spectrometer, the camera images light from plasma onto an array of light detectors, being mentioned 2D imaging of plasma ion temperatures and flow speeds. In addition, compared to a conventional grating spectrometer, the MOSS camera shows an excellent light collecting performance which leads to the improvement of signal to noise ratio and of time resolution. The present paper first describes basic items of MOSS spectroscopy, then follows MOSS camera with an emphasis on the optical system of 2D imaging. (author)

  18. A COMPARISON OF SPECTROSCOPIC VERSUS IMAGING TECHNIQUES FOR DETECTING CLOSE COMPANIONS TO KEPLER OBJECTS OF INTEREST

    Teske, Johanna K.; Everett, Mark E.; Hirsch, Lea; Furlan, Elise; Ciardi, David R.; Horch, Elliott P.; Howell, Steve B.; Gonzales, Erica; Crepp, Justin R.

    2015-01-01

    Kepler planet candidates require both spectroscopic and imaging follow-up observations to rule out false positives and detect blended stars. Traditionally, spectroscopy and high-resolution imaging have probed different host star companion parameter spaces, the former detecting tight binaries and the latter detecting wider bound companions as well as chance background stars. In this paper, we examine a sample of 11 Kepler host stars with companions detected by two techniques—near-infrared adaptive optics and/or optical speckle interferometry imaging, and a new spectroscopic deblending method. We compare the companion effective temperatures (T eff ) and flux ratios (F B /F A , where A is the primary and B is the companion) derived from each technique and find no cases where both companion parameters agree within 1σ errors. In 3/11 cases the companion T eff values agree within 1σ errors, and in 2/11 cases the companion F B /F A values agree within 1σ errors. Examining each Kepler system individually considering multiple avenues (isochrone mapping, contrast curves, probability of being bound), we suggest two cases for which the techniques most likely agree in their companion detections (detect the same companion star). Overall, our results support the advantage that the spectroscopic deblending technique has for finding very close-in companions (θ ≲ 0.″02–0.″05) that are not easily detectable with imaging. However, we also specifically show how high-contrast AO and speckle imaging observations detect companions at larger separations (θ ≥ 0.″02–0.″05) that are missed by the spectroscopic technique, provide additional information for characterizing the companion and its potential contamination (e.g., position angle, separation, magnitude differences), and cover a wider range of primary star effective temperatures. The investigation presented here illustrates the utility of combining the two techniques to reveal higher-order multiples in known

  19. Recent advances in the applications of vibrational spectroscopic imaging and mapping to pharmaceutical formulations

    Ewing, Andrew V.; Kazarian, Sergei G.

    2018-05-01

    Vibrational spectroscopic imaging and mapping approaches have continued in their development and applications for the analysis of pharmaceutical formulations. Obtaining spatially resolved chemical information about the distribution of different components within pharmaceutical formulations is integral for improving the understanding and quality of final drug products. This review aims to summarise some key advances of these technologies over recent years, primarily since 2010. An overview of FTIR, NIR, terahertz spectroscopic imaging and Raman mapping will be presented to give a perspective of the current state-of-the-art of these techniques for studying pharmaceutical samples. This will include their application to reveal spatial information of components that reveals molecular insight of polymorphic or structural changes, behaviour of formulations during dissolution experiments, uniformity of materials and detection of counterfeit products. Furthermore, new advancements will be presented that demonstrate the continuing novel applications of spectroscopic imaging and mapping, namely in FTIR spectroscopy, for studies of microfluidic devices. Whilst much of the recently developed work has been reported by academic groups, examples of the potential impacts of utilising these imaging and mapping technologies to support industrial applications have also been reviewed.

  20. Spectroscopic imaging, diffraction, and holography with x-ray photoemission

    1992-02-01

    X-ray probes are capable of determining the spatial structure of an atom in a specific chemical state, over length scales from about a micron all the way down to atomic resolution. Examples of these probes include photoemission microscopy, energy-dependent photoemission diffraction, photoelectron holography, and X-ray absorption microspectroscopy. Although the method of image formation, chemical-state sensitivity, and length scales can be very different, these X-ray techniques share a common goal of combining a capability for structure determination with chemical-state specificity. This workshop will address recent advances in holographic, diffraction, and direct imaging techniques using X-ray photoemission on both theoretical and experimental fronts. A particular emphasis will be on novel structure determinations with atomic resolution using photoelectrons

  1. Spectroscopic imaging, diffraction, and holography with x-ray photoemission

    1992-02-01

    X-ray probes are capable of determining the spatial structure of an atom in a specific chemical state, over length scales from about a micron all the way down to atomic resolution. Examples of these probes include photoemission microscopy, energy-dependent photoemission diffraction, photoelectron holography, and X-ray absorption microspectroscopy. Although the method of image formation, chemical-state sensitivity, and length scales can be very different, these X-ray techniques share a common goal of combining a capability for structure determination with chemical-state specificity. This workshop will address recent advances in holographic, diffraction, and direct imaging techniques using X-ray photoemission on both theoretical and experimental fronts. A particular emphasis will be on novel structure determinations with atomic resolution using photoelectrons.

  2. High-cadence Imaging and Imaging Spectroscopy at the GREGOR Solar Telescope—A Collaborative Research Environment for High-resolution Solar Physics

    Denker, Carsten; Kuckein, Christoph; Verma, Meetu; González Manrique, Sergio J.; Diercke, Andrea; Enke, Harry; Klar, Jochen; Balthasar, Horst; Louis, Rohan E.; Dineva, Ekaterina

    2018-05-01

    In high-resolution solar physics, the volume and complexity of photometric, spectroscopic, and polarimetric ground-based data significantly increased in the last decade, reaching data acquisition rates of terabytes per hour. This is driven by the desire to capture fast processes on the Sun and the necessity for short exposure times “freezing” the atmospheric seeing, thus enabling ex post facto image restoration. Consequently, large-format and high-cadence detectors are nowadays used in solar observations to facilitate image restoration. Based on our experience during the “early science” phase with the 1.5 m GREGOR solar telescope (2014–2015) and the subsequent transition to routine observations in 2016, we describe data collection and data management tailored toward image restoration and imaging spectroscopy. We outline our approaches regarding data processing, analysis, and archiving for two of GREGOR’s post-focus instruments (see http://gregor.aip.de), i.e., the GREGOR Fabry–Pérot Interferometer (GFPI) and the newly installed High-Resolution Fast Imager (HiFI). The heterogeneous and complex nature of multidimensional data arising from high-resolution solar observations provides an intriguing but also a challenging example for “big data” in astronomy. The big data challenge has two aspects: (1) establishing a workflow for publishing the data for the whole community and beyond and (2) creating a collaborative research environment (CRE), where computationally intense data and postprocessing tools are colocated and collaborative work is enabled for scientists of multiple institutes. This requires either collaboration with a data center or frameworks and databases capable of dealing with huge data sets based on virtual observatory (VO) and other community standards and procedures.

  3. PERSISTENCE MAPPING USING EUV SOLAR IMAGER DATA

    Thompson, B. J. [NASA Goddard Space Flight Center, Code 671, Greenbelt, MD 20771 (United States); Young, C. A., E-mail: barbara.j.thompson@nasa.gov [NASA Goddard Space Flight Center, Code 670, Greenbelt, MD 20771 (United States)

    2016-07-01

    We describe a simple image processing technique that is useful for the visualization and depiction of gradually evolving or intermittent structures in solar physics extreme-ultraviolet imagery. The technique is an application of image segmentation, which we call “Persistence Mapping,” to isolate extreme values in a data set, and is particularly useful for the problem of capturing phenomena that are evolving in both space and time. While integration or “time-lapse” imaging uses the full sample (of size N ), Persistence Mapping rejects ( N − 1)/ N of the data set and identifies the most relevant 1/ N values using the following rule: if a pixel reaches an extreme value, it retains that value until that value is exceeded. The simplest examples isolate minima and maxima, but any quantile or statistic can be used. This paper demonstrates how the technique has been used to extract the dynamics in long-term evolution of comet tails, erupting material, and EUV dimming regions.

  4. Spectroscopic imaging of the pilocarpine model of human epilepsy suggests that early NAA reduction predicts epilepsy.

    Gomes, W A; Lado, F A; de Lanerolle, N C; Takahashi, K; Pan, C; Hetherington, H P

    2007-08-01

    Reduced hippocampal N-acetyl aspartate (NAA) is commonly observed in patients with advanced, chronic temporal lobe epilepsy (TLE). It is unclear, however, whether an NAA deficit is also present during the clinically quiescent latent period that characterizes early TLE. This question has important implications for the use of MR spectroscopic imaging (MRSI) in the early identification of patients at risk for TLE. To determine whether NAA is diminished during the latent period, we obtained high-resolution (1)H spectroscopic imaging during the latent period of the rat pilocarpine model of human TLE. We used actively detuneable surface reception and volume transmission coils to enhance sensitivity and a semiautomated voxel shifting method to accurately position voxels within the hippocampi. During the latent period, 2 and 7 d following pilocarpine treatment, hippocampal NAA was significantly reduced by 27.5 +/- 6.9% (P NAA deficit is not due to neuron loss and therefore likely represents metabolic impairment of hippocampal neurons during the latent phase. Therefore, spectroscopic imaging provides an early marker for metabolic dysfunction in this model of TLE.

  5. Spectroscopic Diagnostics of Solar Magnetic Flux Ropes Using Iron Forbidden Line

    Cheng, X.; Ding, M. D.

    2016-05-01

    In this Letter, we present Interface Region Imaging Spectrograph Fe xxi 1354.08 Å forbidden line emission of two magnetic flux ropes (MFRs) that caused two fast coronal mass ejections with velocities of ≥1000 km s-1 and strong flares (X1.6 and M6.5) on 2014 September 10 and 2015 June 22, respectively. The extreme-ultraviolet images at the 131 and 94 Å passbands provided by the Atmospheric Imaging Assembly on board Solar Dynamics Observatory reveal that both MFRs initially appear as suspended hot channel-like structures. Interestingly, part of the MFRs is also visible in the Fe xxi 1354.08 forbidden line, even prior to the eruption, e.g., for the SOL2014-09-10 event. However, the line emission is very weak and that only appears at a few locations but not the whole structure of the MFRs. This implies that the MFRs could be comprised of different threads with different temperatures and densities, based on the fact that the formation of the Fe xxi forbidden line requires a critical temperature (˜11.5 MK) and density. Moreover, the line shows a non-thermal broadening and a blueshift in the early phase. It suggests that magnetic reconnection at that time has initiated; it not only heats the MFR and, at the same time, produces a non-thermal broadening of the Fe xxi line but also produces the poloidal flux, leading to the ascension of the MFRs.

  6. SPECTROSCOPIC DIAGNOSTICS OF SOLAR MAGNETIC FLUX ROPES USING IRON FORBIDDEN LINE

    Cheng, X.; Ding, M. D.

    2016-01-01

    In this Letter, we present Interface Region Imaging Spectrograph Fe xxi 1354.08 Å forbidden line emission of two magnetic flux ropes (MFRs) that caused two fast coronal mass ejections with velocities of ≥1000 km s"−"1 and strong flares (X1.6 and M6.5) on 2014 September 10 and 2015 June 22, respectively. The extreme-ultraviolet images at the 131 and 94 Å passbands provided by the Atmospheric Imaging Assembly on board Solar Dynamics Observatory reveal that both MFRs initially appear as suspended hot channel-like structures. Interestingly, part of the MFRs is also visible in the Fe xxi 1354.08 forbidden line, even prior to the eruption, e.g., for the SOL2014-09-10 event. However, the line emission is very weak and that only appears at a few locations but not the whole structure of the MFRs. This implies that the MFRs could be comprised of different threads with different temperatures and densities, based on the fact that the formation of the Fe xxi forbidden line requires a critical temperature (∼11.5 MK) and density. Moreover, the line shows a non-thermal broadening and a blueshift in the early phase. It suggests that magnetic reconnection at that time has initiated; it not only heats the MFR and, at the same time, produces a non-thermal broadening of the Fe xxi line but also produces the poloidal flux, leading to the ascension of the MFRs.

  7. SPECTROSCOPIC DIAGNOSTICS OF SOLAR MAGNETIC FLUX ROPES USING IRON FORBIDDEN LINE

    Cheng, X.; Ding, M. D., E-mail: xincheng@nju.edu.cn [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China)

    2016-05-20

    In this Letter, we present Interface Region Imaging Spectrograph Fe xxi 1354.08 Å forbidden line emission of two magnetic flux ropes (MFRs) that caused two fast coronal mass ejections with velocities of ≥1000 km s{sup −1} and strong flares (X1.6 and M6.5) on 2014 September 10 and 2015 June 22, respectively. The extreme-ultraviolet images at the 131 and 94 Å passbands provided by the Atmospheric Imaging Assembly on board Solar Dynamics Observatory reveal that both MFRs initially appear as suspended hot channel-like structures. Interestingly, part of the MFRs is also visible in the Fe xxi 1354.08 forbidden line, even prior to the eruption, e.g., for the SOL2014-09-10 event. However, the line emission is very weak and that only appears at a few locations but not the whole structure of the MFRs. This implies that the MFRs could be comprised of different threads with different temperatures and densities, based on the fact that the formation of the Fe xxi forbidden line requires a critical temperature (∼11.5 MK) and density. Moreover, the line shows a non-thermal broadening and a blueshift in the early phase. It suggests that magnetic reconnection at that time has initiated; it not only heats the MFR and, at the same time, produces a non-thermal broadening of the Fe xxi line but also produces the poloidal flux, leading to the ascension of the MFRs.

  8. X-ray imaging spectroscopic diagnostics on Nike

    Aglitskiy, Y.; Karasik, M.; Serlin, V.; Weaver, J. L.; Oh, J.; Obenschain, S. P.; Ralchenko, Yu.

    2017-10-01

    Electron temperature and density diagnostics of the laser plasma produced within the focal spot of the NRL's Nike laser are being explored with the help of X-ray imaging spectroscopy. Spectra of He-like and H-like ions were taken by Nike focusing spectrometers in a range of lower (1.8 kev, Si XIV) and higher (6.7 kev, Fe XXV) x-ray energies. Data that were obtained with spatial resolution were translated into the temperature and density as functions of distance from the target. As an example electron density was determined from He-like satellites to Ly-alpha in Si XIV. The dielectronic satellites with intensity ratios that are sensitive to collisional transfer of population between different triplet groups of double-excited states 2l2l' in Si XIII were observed with high spatial and spectral resolution Lineouts taken at different axial distances from the planar Si target show changing spectral shapes due to the different electron densities as determined by supporting non-LTE simulations. These shapes are relatively insensitive to the plasma temperature which was measured using different spectral lines. This work was supported by the US DOE/NNSA.

  9. Application of imaging spectroscopic reflectometry for characterization of gold reduction from organometallic compound by means of plasma jet technology

    Vodák, Jiří, E-mail: jiri.vodak@yahoo.com [Institute of Physical Engineering, Faculty of Mechanical Engineering, Brno University of Technology, Technická 2, 616 69 Brno (Czech Republic); Nečas, David [RG Plasma Technologies, CEITEC Masaryk University, Kamenice 5, 625 00 Brno (Czech Republic); Pavliňák, David [Department of Physical Electronics, Masaryk University, Kotlářská 2, 611 37 Brno (Czech Republic); Macak, Jan M [Center of Materials and Nanotechnologies, Faculty of Chemical Technology, University of Pardubice, Nám. Čs. Legií 565, 530 02 Pardubice (Czech Republic); Řičica, Tomáš; Jambor, Roman [Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice (Czech Republic); Ohlídal, Miloslav [Institute of Physical Engineering, Faculty of Mechanical Engineering, Brno University of Technology, Technická 2, 616 69 Brno (Czech Republic); Institute of Physics, Faculty of Mining and Geology, VŠB – Technical University of Ostrava (Czech Republic)

    2017-02-28

    Highlights: • Metallic gold is reduced from an organometallic compound layer using a plasma jet. • Imaging spectroscopic reflectometry is used to locate areas with metallic gold. • The results are completed with XPS and optical microscopy observations. - Abstract: This work presents a new application of imaging spectroscopic reflectometry to determine a distribution of metallic gold in a layer of an organogold precursor which was treated by a plasma jet. Gold layers were prepared by spin coating from a solution of the precursor containing a small amount of polyvinylpyrrolidone on a microscopy glass, then they were vacuum dried. A difference between reflectivity of metallic gold and the precursor was utilized by imaging spectroscopic reflectometry to create a map of metallic gold distribution using a newly developed model of the studied sample. The basic principle of the imaging spectroscopic reflectometry is also shown together with the data acquisition principles. XPS measurements and microscopy observations were made to complete the imaging spectroscopic reflectometry results. It is proved that the imaging spectroscopic reflectometry represents a new method for quantitative evaluation of local reduction of metallic components from metaloorganic compounds.

  10. Automatic detection of solar features in HSOS full-disk solar images using guided filter

    Yuan, Fei; Lin, Jiaben; Guo, Jingjing; Wang, Gang; Tong, Liyue; Zhang, Xinwei; Wang, Bingxiang

    2018-02-01

    A procedure is introduced for the automatic detection of solar features using full-disk solar images from Huairou Solar Observing Station (HSOS), National Astronomical Observatories of China. In image preprocessing, median filter is applied to remove the noises. Guided filter is adopted to enhance the edges of solar features and restrain the solar limb darkening, which is first introduced into the astronomical target detection. Then specific features are detected by Otsu algorithm and further threshold processing technique. Compared with other automatic detection procedures, our procedure has some advantages such as real time and reliability as well as no need of local threshold. Also, it reduces the amount of computation largely, which is benefited from the efficient guided filter algorithm. The procedure has been tested on one month sequences (December 2013) of HSOS full-disk solar images and the result shows that the number of features detected by our procedure is well consistent with the manual one.

  11. Combined spectroscopic imaging and chemometric approach for automatically partitioning tissue types in human prostate tissue biopsies

    Haka, Abigail S.; Kidder, Linda H.; Lewis, E. Neil

    2001-07-01

    We have applied Fourier transform infrared (FTIR) spectroscopic imaging, coupling a mercury cadmium telluride (MCT) focal plane array detector (FPA) and a Michelson step scan interferometer, to the investigation of various states of malignant human prostate tissue. The MCT FPA used consists of 64x64 pixels, each 61 micrometers 2, and has a spectral range of 2-10.5 microns. Each imaging data set was collected at 16-1 resolution, resulting in 512 image planes and a total of 4096 interferograms. In this article we describe a method for separating different tissue types contained within FTIR spectroscopic imaging data sets of human prostate tissue biopsies. We present images, generated by the Fuzzy C-Means clustering algorithm, which demonstrate the successful partitioning of distinct tissue type domains. Additionally, analysis of differences in the centroid spectra corresponding to different tissue types provides an insight into their biochemical composition. Lastly, we demonstrate the ability to partition tissue type regions in a different data set using centroid spectra calculated from the original data set. This has implications for the use of the Fuzzy C-Means algorithm as an automated technique for the separation and examination of tissue domains in biopsy samples.

  12. Sensitivity-encoded (SENSE) proton echo-planar spectroscopic imaging (PEPSI) in the human brain.

    Lin, Fa-Hsuan; Tsai, Shang-Yueh; Otazo, Ricardo; Caprihan, Arvind; Wald, Lawrence L; Belliveau, John W; Posse, Stefan

    2007-02-01

    Magnetic resonance spectroscopic imaging (MRSI) provides spatially resolved metabolite information that is invaluable for both neuroscience studies and clinical applications. However, lengthy data acquisition times, which are a result of time-consuming phase encoding, represent a major challenge for MRSI. Fast MRSI pulse sequences that use echo-planar readout gradients, such as proton echo-planar spectroscopic imaging (PEPSI), are capable of fast spectral-spatial encoding and thus enable acceleration of image acquisition times. Combining PEPSI with recent advances in parallel MRI utilizing RF coil arrays can further accelerate MRSI data acquisition. Here we investigate the feasibility of ultrafast spectroscopic imaging at high field (3T and 4T) by combining PEPSI with sensitivity-encoded (SENSE) MRI using eight-channel head coil arrays. We show that the acquisition of single-average SENSE-PEPSI data at a short TE (15 ms) can be accelerated to 32 s or less, depending on the field strength, to obtain metabolic images of choline (Cho), creatine (Cre), N-acetyl-aspartate (NAA), and J-coupled metabolites (e.g., glutamate (Glu) and inositol (Ino)) with acceptable spectral quality and localization. The experimentally measured reductions in signal-to-noise ratio (SNR) and Cramer-Rao lower bounds (CRLBs) of metabolite resonances were well explained by both the g-factor and reduced measurement times. Thus, this technology is a promising means of reducing the scan times of 3D acquisitions and time-resolved 2D measurements. Copyright (c) 2007 Wiley-Liss, Inc.

  13. Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber

    Rosenberg Petersen, Christian; Prtljaga, Nikola; Farries, Mark; Ward, Jon; Napier, Bruce; Lloyd, Gavin Rhys; Nallala, Jayakrupakar; Stone, Nick; Bang, Ole

    2018-02-01

    We present the first demonstration of mid-infrared spectroscopic imaging of human tissue using a fiber-coupled supercontinuum source spanning from 2-7.5 μm. The supercontinuum was generated in a tapered large mode area chalcogenide photonic crystal fiber in order to obtain broad bandwidth, high average power, and single-mode output for good imaging properties. Tissue imaging was demonstrated in transmission by raster scanning over a sub-mm region of paraffinized colon tissue on CaF2 substrate, and the signal was measured using a fiber-coupled grating spectrometer. This demonstration has shown that we can distinguish between epithelial and surrounding connective tissues within a paraffinized section of colon tissue by imaging at discrete wavelengths related to distinct chemical absorption features.

  14. A COMPARISON OF SPECTROSCOPIC VERSUS IMAGING TECHNIQUES FOR DETECTING CLOSE COMPANIONS TO KEPLER OBJECTS OF INTEREST

    Teske, Johanna K. [Carnegie DTM, 5241 Broad Branch Road, NW, Washington, DC 20015 (United States); Everett, Mark E. [National Optical Astronomy Observatory, 950 N. Cherry Ave., Tucson, AZ 85719 (United States); Hirsch, Lea [Astronomy Department, University of California at Berkeley, Berkeley, CA 94720 (United States); Furlan, Elise; Ciardi, David R. [NASA Exoplanet Science Institute, California Institute of Technology, 770 South Wilson Ave., Pasadena, CA 91125 (United States); Horch, Elliott P. [Department of Physics, Southern Connecticut State University, 501 Crescent Street, New Haven, CT 06515 (United States); Howell, Steve B. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Gonzales, Erica; Crepp, Justin R., E-mail: jteske@carnegiescience.edu [Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN 46556 (United States)

    2015-11-15

    Kepler planet candidates require both spectroscopic and imaging follow-up observations to rule out false positives and detect blended stars. Traditionally, spectroscopy and high-resolution imaging have probed different host star companion parameter spaces, the former detecting tight binaries and the latter detecting wider bound companions as well as chance background stars. In this paper, we examine a sample of 11 Kepler host stars with companions detected by two techniques—near-infrared adaptive optics and/or optical speckle interferometry imaging, and a new spectroscopic deblending method. We compare the companion effective temperatures (T{sub eff}) and flux ratios (F{sub B}/F{sub A}, where A is the primary and B is the companion) derived from each technique and find no cases where both companion parameters agree within 1σ errors. In 3/11 cases the companion T{sub eff} values agree within 1σ errors, and in 2/11 cases the companion F{sub B}/F{sub A} values agree within 1σ errors. Examining each Kepler system individually considering multiple avenues (isochrone mapping, contrast curves, probability of being bound), we suggest two cases for which the techniques most likely agree in their companion detections (detect the same companion star). Overall, our results support the advantage that the spectroscopic deblending technique has for finding very close-in companions (θ ≲ 0.″02–0.″05) that are not easily detectable with imaging. However, we also specifically show how high-contrast AO and speckle imaging observations detect companions at larger separations (θ ≥ 0.″02–0.″05) that are missed by the spectroscopic technique, provide additional information for characterizing the companion and its potential contamination (e.g., position angle, separation, magnitude differences), and cover a wider range of primary star effective temperatures. The investigation presented here illustrates the utility of combining the two techniques to reveal higher

  15. GOES-12 Solar X-ray Imager Archive

    National Oceanic and Atmospheric Administration, Department of Commerce — The GOES Solar X-ray Imager is integrated into the GOES-12 satellite, whose primary mission is to provide Earth-weather monitoring. The SXI is operated by NOAA's...

  16. An important step forward in continuous spectroscopic imaging of ionising radiations using ASICs

    Fessler, P. [11 rue Rabelais, 92170 Vanves (France); Coffin, J. [Institut de Recherches Subatomiques, B.P. 28, 67037 Strasbourg (France); Eberle, H. [Institut de Recherches Subatomiques, B.P. 28, 67037 Strasbourg (France); Raad Iseli, C. de [Smart Silicon Systems SA, Ch. de la Graviere 6, CH-1007 Lausanne (Switzerland); Hilt, B. [Universite de Haute-Alsace, GRPHE, 61, rue Albert Camus, 68093 Mulhouse (France); Huss, D. [Universite de Haute-Alsace, GRPHE, 61, rue Albert Camus, 68093 Mulhouse (France); Krummenacher, F. [Smart Silicon Systems SA, Ch. de la Graviere 6, CH-1007 Lausanne (Switzerland); Lutz, J.R. [Institut de Recherches Subatomiques, B.P. 28, 67037 Strasbourg (France); Prevot, G. [Institut de Recherches Subatomiques, B.P. 28, 67037 Strasbourg (France); Renouprez, A. [Institut de Recherche sur la Catalyse, 2 Avenue Albert Einstein, 69626 Villeurbanne (France); Sigward, M.H. [Institut de Recherches Subatomiques, B.P. 28, 67037 Strasbourg (France); Schwaller, B. [Universite de Haute-Alsace, GRPHE, 61, rue Albert Camus, 68093 Mulhouse (France); Voltolini, C. [Institut de Recherches Subatomiques, B.P. 28, 67037 Strasbourg (France)

    1999-01-21

    Characterization results are given for an original ASIC allowing continuous acquisition of ionising radiation images in spectroscopic mode. Ionising radiation imaging in general and spectroscopic imaging in particular must primarily be guided by the attempt to decrease statistical noise, which requires detection systems designed to allow very high counting rates. Any source of dead time must therefore be avoided. Thus, the use of on-line corrections of the inevitable dispersion of characteristics between the large number of electronic channels of the detection system, shall be precluded. Without claiming to achieve ultimate noise levels, the work described is focused on how to prevent good individual acquisition channel noise performance from being totally destroyed by the dispersion between channels without introducing dead times. With this goal, we developed an automatic charge amplifier output voltage offset compensation system which operates regardless of the cause of the offset (detector or electronic). The main performances of the system are the following: the input equivalent noise charge is 190 e rms (input non connected, peaking time 500 ns), the highest gain is 255 mV/fC, the peaking time is adjustable between 200 ns and 2 {mu}s and the power consumption is 10 mW per channel. The agreement between experimental data and theoretical simulation results is excellent.

  17. An important step forward in continuous spectroscopic imaging of ionising radiations using ASICs

    Fessler, P.; Coffin, J.; Eberle, H.; Raad Iseli, C. de; Hilt, B.; Huss, D.; Krummenacher, F.; Lutz, J.R.; Prevot, G.; Renouprez, A.; Sigward, M.H.; Schwaller, B.; Voltolini, C.

    1999-01-01

    Characterization results are given for an original ASIC allowing continuous acquisition of ionising radiation images in spectroscopic mode. Ionising radiation imaging in general and spectroscopic imaging in particular must primarily be guided by the attempt to decrease statistical noise, which requires detection systems designed to allow very high counting rates. Any source of dead time must therefore be avoided. Thus, the use of on-line corrections of the inevitable dispersion of characteristics between the large number of electronic channels of the detection system, shall be precluded. Without claiming to achieve ultimate noise levels, the work described is focused on how to prevent good individual acquisition channel noise performance from being totally destroyed by the dispersion between channels without introducing dead times. With this goal, we developed an automatic charge amplifier output voltage offset compensation system which operates regardless of the cause of the offset (detector or electronic). The main performances of the system are the following: the input equivalent noise charge is 190 e rms (input non connected, peaking time 500 ns), the highest gain is 255 mV/fC, the peaking time is adjustable between 200 ns and 2 μs and the power consumption is 10 mW per channel. The agreement between experimental data and theoretical simulation results is excellent

  18. A Compton camera for spectroscopic imaging from 100 keV to 1 MeV

    Earnhart, J.R.D.

    1998-01-01

    A review of spectroscopic imaging issues, applications, and technology is presented. Compton cameras based on solid state semiconductor detectors stands out as the best system for the nondestructive assay of special nuclear materials. A camera for this application has been designed based on an efficient specific purpose Monte Carlo code developed for this project. Preliminary experiments have been performed which demonstrate the validity of the Compton camera concept and the accuracy of the code. Based on these results, a portable prototype system is in development. Proposed future work is addressed

  19. Infrared Images of an Infant Solar System

    2002-05-01

    ESO Telescopes Detect a Strange-Looking Object Summary Using the ESO 3.5-m New Technology Telescope and the Very Large Telescope (VLT) , a team of astronomers [1] have discovered a dusty and opaque disk surrounding a young solar-type star in the outskirts of a dark cloud in the Milky Way. It was found by chance during an unrelated research programme and provides a striking portrait of what our Solar System must have looked like when it was in its early infancy. Because of its striking appearance, the astronomers have nicknamed it the "Flying Saucer" . The new object appears to be a perfect example of a very young star with a disk in which planets are forming or will soon form, and located far away from the usual perils of an active star-forming environment . Most other young stars, especially those that are born in dense regions, run a serious risk of having their natal dusty disks destroyed by the blazing radiation of their more massive and hotter siblings in these clusters. The star at the centre of the "Flying Saucer", seems destined to live a long and quiet life at the centre of a planetary system , very much like our own Sun. This contributes to making it a most interesting object for further studies with the VLT and other telescopes. The mass of the observed disk of gas and dust is at least twice that of the planet Jupiter and its radius measures about 45 billion km, or 5 times the size of the orbit of Neptune. PR Photo 12a/02 : The "Flying Saucer" object photographed with NTT/SOFI. PR Photo 12b/02 : VLT/ISAAC image of this object. PR Photo 12c/02 : Enlargement of VLT/ISAAC image . Circumstellar Disks and Planets Planets form in dust disks around young stars. This is a complex process of which not all stages are yet fully understood but it begins when small dust particles collide and stick to each other. For this reason, observations of such dust disks, in particular those that appear as extended structures (are "resolved"), are very important for our

  20. Prostate cancer in magnetic resonance imaging: diagnostic utilites of spectroscopic sequences

    Caivano, Rocchina; Cirillo, Patrizia; Lotumolo, Antonella; Fortunato, Giovanna; Zandolino, Alexis; Cammarota, Aldo; Balestra, Antonio; Macarini, Luca; Vita, Giulia

    2012-01-01

    The aim of our work is to determine the efficacy of a combined study 3 Tesla Magnetic Resonance Imaging (3T MRI), with phased-array coil, for the detection of prostate cancer using magnetic resonance spectroscopy (MRS) and diffusion-weighted images (DWI) in identifying doubt nodules. In this study, we prospectively studied 46 patients who consecutively underwent digital-rectal exploration for high doses of prostate specific antigen (PSA), as well as a MRI examination and a subsequent rectal biopsy. The study of magnetic resonance imaging was performed with a Philips Achieva 3T scanner and phased-array coil. The images were obtained with turbo spin-echo sequences T2-weighted images, T1-weighted before and after the administration of contrast medium, DWI sequences and 3D spectroscopic sequences. The ultrasound-guided prostate biopsy was performed approximately 15 days after the MRI. The data obtained from MR images and spectroscopy were correlated with histological data. MRI revealed sensitivity and specificity of 88% and 61% respectively and positive predictive value (PPV) of 73%, negative predicted value (NPV) of 81% and accuracy of 76%. In identifying the location of prostate cancer, the sensitivity of 3T MRS was 92%, with a specificity of 89%, PPV of 87%, NPV of 88% and accuracy of 87%; DWI showed a sensitivity of 88%, specificity of 61%, PPV of 73%, NPV of 81% and accuracy of 76%. The 3T MR study with phased-array coil and the use of DWI and spectroscopic sequences, in addition to T2-weighted sequences, revealed to be accurate in the diagnosis of prostate cancer and in the identification of nodules to be biopsied. It may be indicated as a resolute way before biopsy in patients with elevated PSA value and can be proposed in the staging and follow-up.

  1. High-flux solar concentration with imaging designs

    Feuermann, D. [Ben-Gurion University of the Negev (Israel). Jacob Blaustein Institute for Desert Research; Gordon, J.M. [Ben-Gurion University of the Negev (Israel). Jacob Blaustein Institute for Desert Research; Ben-Gurion University of the Negev (Israel). Dept. of Mechanical Engineering; Ries, H. [Ries and Partners, Munich (Germany)

    1999-02-01

    Most large solar concentrators designed for high flux concentration at high collection efficiency are based on imaging primary mirrors and nonimaging secondary concentrators. In this paper, we offer an alternative purely imaging two-stage solar concentrator that can attain high flux concentration at high collection efficiency. Possible practical virtues include: (1) an inherent large gap between absorber and secondary mirror; (2) a restricted angular range on the absorber; and (3) an upward-facing receiver where collected energy can be extracted via the (shaded) apex of the parabola. We use efficiency-concentration plots to characterize the solar concentrators considered, and to evaluate the potential improvements with secondary concentrators. (author)

  2. Dual-wavelength differential spectroscopic imaging for diagnostics of laser-induced plasma

    Motto-Ros, V., E-mail: vincent.motto-ros@univ-lyon1.fr [Universite de Lyon, F-69622, Lyon, Universite Lyon 1, Villeurbanne, CNRS, UMR5579, LASIM (France); Ma, Q.L. [Universite de Lyon, F-69622, Lyon, Universite Lyon 1, Villeurbanne, CNRS, UMR5579, LASIM (France); Gregoire, S. [CRITT Matriaux Alsace, 19 rue de St Junien, 67300 Schiltigheim (France); Lei, W.Q.; Wang, X.C. [Universite de Lyon, F-69622, Lyon, Universite Lyon 1, Villeurbanne, CNRS, UMR5579, LASIM (France); Pelascini, F.; Surma, F. [CRITT Matriaux Alsace, 19 rue de St Junien, 67300 Schiltigheim (France); Detalle, V. [Laboratoire de Recherche des Monuments Historiques, 29 rue de Paris, 77420 Champs-sur-Marne (France); Yu, J. [Universite de Lyon, F-69622, Lyon, Universite Lyon 1, Villeurbanne, CNRS, UMR5579, LASIM (France)

    2012-08-15

    A specific configuration for plasma fast spectroscopic imaging was developed, where a pair of narrowband filters, one fitting an emission line of a species to be studied and the other out of its emission line, allowed double images to be taken for a laser-induced plasma. A dedicated software was developed for the subtraction between the double images. The result represents therefore the monochromatic emission image of the species in the plasma. We have shown in this work that such configuration is especially efficient for the monitoring of a plasma generated under the atmospheric pressure at very short delays after the impact of the laser pulse on the target, when a strong continuum emission is observed. The efficiency of the technique has been particularly demonstrated in the study of laser-induced plasma on a polymer target. Molecular species, such as C{sub 2} and CN, as well as atomic species, such as C and N, were imaged starting from 50 ns after the laser impact. Moreover space segregation of different species, atomic or molecular, inside of the plasma was clearly observed. - Highlights: Black-Right-Pointing-Pointer Imaging to study species with time and space resolution in laser induced plasma. Black-Right-Pointing-Pointer Image display of multiple species is proposed based on RGB color model. Black-Right-Pointing-Pointer Molecular emission (CN and C{sub 2}) is observed at very short delays (50 ns). Black-Right-Pointing-Pointer Segregation of different species inside the plasma is clearly established.

  3. Characterization of μc-Si:H/a-Si:H tandem solar cell structures by spectroscopic ellipsometry

    Murata, Daisuke; Yuguchi, Tetsuya; Fujiwara, Hiroyuki

    2014-01-01

    In order to perform the structural characterization of Si thin-film solar cells having submicron-size rough textured surfaces, we have developed an optical model that can be utilized for the spectroscopic ellipsometry (SE) analysis of a multilayer solar cell structure consisting of hydrogenated amorphous silicon (a-Si:H) and microcrystalline silicon (μc-Si:H) layers fabricated on textured SnO 2 :F substrates. To represent the structural non-uniformity in the textured structure, the optical response has been calculated from two regions with different thicknesses of the Si layers. Moreover, in the optical model, the interface layers are modeled by multilayer structures assuming two-phase composites and the volume fractions of the phases in the layers are controlled by the structural curvature factor. The polarized reflection from the μc-Si:H layer that shows extensive surface roughening during the growth has also been modeled. In this study, a state-of-the-art solar cell structure with the textured μc-Si:H (2000 nm)/ZnO (100 nm)/a-Si:H (200 nm)/SnO 2 :F/glass substrate structure has been characterized. The μc-Si:H/a-Si:H textured structure deduced from our SE analysis shows remarkable agreement with that observed by transmission electron microscopy. From the above results, we have demonstrated the high-precision characterization of highly-textured μc-Si:H/a-Si:H solar cell structures. - Highlights: • Characterization of textured μc-Si:H/a-Si:H solar cell structures by ellipsometry • A new optical model using surface area and multilayer models • High precision characterization of submicron-range rough interface structures

  4. Spectroscopic imaging studies of nanoscale polarity and mass transport phenomena in self-assembled organic nanotubes.

    Xu, Hao; Nagasaka, Shinobu; Kameta, Naohiro; Masuda, Mitsutoshi; Ito, Takashi; Higgins, Daniel A

    2017-08-02

    Synthetic organic nanotubes self-assembled from bolaamphiphile surfactants are now being explored for use as drug delivery vehicles. In this work, several factors important to their implementation in drug delivery are explored. All experiments are performed with the nanotubes immersed in ethanol. First, Nile Red (NR) and a hydroxylated Nile Red derivative (NR-OH) are loaded into the nanotubes and spectroscopic fluorescence imaging methods are used to determine the apparent dielectric constant of their local environment. Both are found in relatively nonpolar environments, with the NR-OH molecules preferring regions of relatively higher dielectric constant compared to NR. Unique two-color imaging fluorescence correlation spectroscopy (imaging FCS) measurements are then used along with the spectroscopic imaging results to deduce the dielectric properties of the environments sensed by mobile and immobile populations of probe molecules. The results reveal that mobile NR molecules pass through less polar regions, likely within the nanotube walls, while immobile NR molecules are found in more polar regions, possibly near the nanotube surfaces. In contrast, mobile and immobile NR-OH molecules are found to locate in environments of similar polarity. The imaging FCS results also provide quantitative data on the apparent diffusion coefficient for each dye. The mean diffusion coefficient for the NR dye was approximately two-fold larger than that of NR-OH. Slower diffusion by the latter could result from its additional hydrogen bonding interactions with polar triglycine, amine, and glucose moieties near the nanotube surfaces. The knowledge gained in these studies will allow for the development of nanotubes that are better engineered for applications in the controlled transport and release of uncharged, dipolar drug molecules.

  5. A compact imaging spectroscopic system for biomolecular detections on plasmonic chips.

    Lo, Shu-Cheng; Lin, En-Hung; Wei, Pei-Kuen; Tsai, Wan-Shao

    2016-10-17

    In this study, we demonstrate a compact imaging spectroscopic system for high-throughput detection of biomolecular interactions on plasmonic chips, based on a curved grating as the key element of light diffraction and light focusing. Both the curved grating and the plasmonic chips are fabricated on flexible plastic substrates using a gas-assisted thermal-embossing method. A fiber-coupled broadband light source and a camera are included in the system. Spectral resolution within 1 nm is achieved in sensing environmental index solutions and protein bindings. The detected sensitivities of the plasmonic chip are comparable with a commercial spectrometer. An extra one-dimensional scanning stage enables high-throughput detection of protein binding on a designed plasmonic chip consisting of several nanoslit arrays with different periods. The detected resonance wavelengths match well with the grating equation under an air environment. Wavelength shifts between 1 and 9 nm are detected for antigens of various concentrations binding with antibodies. A simple, mass-productive and cost-effective method has been demonstrated on the imaging spectroscopic system for real-time, label-free, highly sensitive and high-throughput screening of biomolecular interactions.

  6. Characterization of intact subcellular bodies in whole bacteria by cryo-electron tomography and spectroscopic imaging.

    Comolli, L R; Kundmann, M; Downing, K H

    2006-07-01

    We illustrate the combined use of cryo-electron tomography and spectroscopic difference imaging in the study of subcellular structure and subcellular bodies in whole bacteria. We limited our goal and focus to bodies with a distinct elemental composition that was in a sufficiently high concentration to provide the necessary signal-to-noise level at the relatively large sample thicknesses of the intact cell. This combination proved very powerful, as demonstrated by the identification of a phosphorus-rich body in Caulobacter crescentus. We also confirmed the presence of a body rich in carbon, demonstrated that these two types of bodies are readily recognized and distinguished from each other, and provided, for the first time to our knowledge, structural information about them in their intact state. In addition, we also showed the presence of a similar type of phosphorus-rich body in Deinococcus grandis, a member of a completely unrelated bacteria genus. Cryo-electron microscopy and tomography allowed the study of the biogenesis and morphology of these bodies at resolutions better than 10 nm, whereas spectroscopic difference imaging provided a direct identification of their chemical composition.

  7. Characterization of cytochrome c as marker for retinal cell degeneration by uv/vis spectroscopic imaging

    Hollmach, Julia; Schweizer, Julia; Steiner, Gerald; Knels, Lilla; Funk, Richard H. W.; Thalheim, Silko; Koch, Edmund

    2011-07-01

    Retinal diseases like age-related macular degeneration have become an important cause of visual loss depending on increasing life expectancy and lifestyle habits. Due to the fact that no satisfying treatment exists, early diagnosis and prevention are the only possibilities to stop the degeneration. The protein cytochrome c (cyt c) is a suitable marker for degeneration processes and apoptosis because it is a part of the respiratory chain and involved in the apoptotic pathway. The determination of the local distribution and oxidative state of cyt c in living cells allows the characterization of cell degeneration processes. Since cyt c exhibits characteristic absorption bands between 400 and 650 nm wavelength, uv/vis in situ spectroscopic imaging was used for its characterization in retinal ganglion cells. The large amount of data, consisting of spatial and spectral information, was processed by multivariate data analysis. The challenge consists in the identification of the molecular information of cyt c. Baseline correction, principle component analysis (PCA) and cluster analysis (CA) were performed in order to identify cyt c within the spectral dataset. The combination of PCA and CA reveals cyt c and its oxidative state. The results demonstrate that uv/vis spectroscopic imaging in conjunction with sophisticated multivariate methods is a suitable tool to characterize cyt c under in situ conditions.

  8. (31) P MR spectroscopic imaging combined with (1) H MR spectroscopic imaging in the human prostate using a double tuned endorectal coil at 7T.

    Luttje, Mariska P; Italiaander, Michel G M; Arteaga de Castro, Catalina S; van der Kemp, Wybe J M; Luijten, Peter R; van Vulpen, Marco; van der Heide, Uulke A; Klomp, Dennis W J

    2014-12-01

    Improved diagnostic sensitivity could be obtained in cancer detection and staging when individual compounds of the choline pool can be detected. Therefore, a novel coil design is proposed, providing the ability to acquire both (1) H and (31) P magnetic resonance spectroscopic imaging (MRSI) in patients with prostate cancer. A two-element (1) H/(31) P endorectal coil was designed by adjusting a commercially available 3T endorectal coil. The two-element coil setup was interfaced as a transceiver to a whole body 7T MR scanner. Simulations and phantom measurements were performed to compare the efficiency of the coil. (1) H MRSI and (31) P MRSI were acquired in vivo in prostate cancer patients. The efficiency of the (1) H/(31) P coil is comparable to the dual channel (1) H coil previously published. Individually distinguishable phospholipid metabolites in the in vivo (31) P spectra were: phosphoethanolamine, phosphocholine, phosphate, glycerophosphoethanolamine, glycerophosphocholine, phosphocreatine, and adenosine triposphate. (1) H MRSI was performed within the same scan session, visualizing choline, polyamines, creatine, and citrate. (1) H MRSI and (31) P MRSI can be acquired in the human prostate at 7T within the same scan session using an endorectal coil matched and tuned for (1) H (quadrature) and (31) P (linear) without the need of cable traps and with negligible efficiency losses in the (1) H and (31) P channel. © 2013 Wiley Periodicals, Inc.

  9. Detection of prostate cancer with MR spectroscopic imaging: an expanded paradigm incorporating polyamines

    Shukla-Dave, A.; Hricak, H.; Moskowitz, C.; Ishill, N.; Akin, O.; Kuroiwa, K.; Spector, J.; Kumar, M.; Reuter, V.E.; Koutcher, J.A.; Zakian, K.L. [Memorial Sloan-Kettering Cancer Center, New York, NY (United States). Dept. of Medical Physics

    2007-11-15

    Purpose: To characterize benign and malignant prostate peripheral zone (PZ) tissue retrospectively by using a commercial magnetic resonance (MR) spectroscopic imaging package and incorporating the choline plus creatine-to-citrate ratio ([Cho + Cr]/Cit) and polyamine (PA) information into a statistically based voxel classification procedure. Materials and methods: The institutional review board approved this HIPAA-compliant study and waived the requirement for informed consent. Fifty men (median age, 60 years; range, 44-69 years) with untreated biopsy-proved prostate cancer underwent combined endorectal MR imaging and MR spectroscopic imaging. Commercial software was used to acquire and process MR spectroscopic imaging data. The (Cho + Cr)/Cit and the PA level were tabulated for each voxel. The PA level was scored on a scale of 0 (PA undetectable) to 2 (PA peak as high as or higher than Cho peak). Whole-mount step-section histopathologic analysis constituted the reference standard. Classification and regression tree analysis in a training set generated a decision-making tree (rule) for classifying voxels as malignant or benign, which was validated in a test set. Receiver operating characteristic and generalized estimating equation regression analyses were used to assess accuracy and sensitivity, respectively. Results: The median (Cho + Cr)/Cit was 0.55 (mean {+-} standard deviation, 0.59 {+-} 0.03) in benign and 0.77 (mean, 1.08 {+-} 0.20) in malignant PZ voxels (P = .027). A significantly higher percentage of benign (compared with malignant) voxels had higher PA than choline peaks (P < .001). In the 24-patient training set (584 voxels), the rule yielded 54% sensitivity and 91% specificity for cancer detection; in the 26-patient test set (667 voxels), it yielded 42% sensitivity and 85% specificity. The percentage of cancer in the voxel at histopathologic analysis correlated positively (P < .001) with the sensitivity of the classification and regression tree rule

  10. Performance assessment of diffuse optical spectroscopic imaging instruments in a 2-year multicenter breast cancer trial

    Leproux, Anaïs; O'Sullivan, Thomas D.; Cerussi, Albert; Durkin, Amanda; Hill, Brian; Hylton, Nola; Yodh, Arjun G.; Carp, Stefan A.; Boas, David; Jiang, Shudong; Paulsen, Keith D.; Pogue, Brian; Roblyer, Darren; Yang, Wei; Tromberg, Bruce J.

    2017-12-01

    We present a framework for characterizing the performance of an experimental imaging technology, diffuse optical spectroscopic imaging (DOSI), in a 2-year multicenter American College of Radiology Imaging Network (ACRIN) breast cancer study (ACRIN-6691). DOSI instruments combine broadband frequency-domain photon migration with time-independent near-infrared (650 to 1000 nm) spectroscopy to measure tissue absorption and reduced scattering spectra and tissue hemoglobin, water, and lipid composition. The goal of ACRIN-6691 was to test the effectiveness of optically derived imaging endpoints in predicting the final pathologic response of neoadjuvant chemotherapy (NAC). Sixty patients were enrolled over a 2-year period at participating sites and received multiple DOSI scans prior to and during 3- to 6-month NAC. The impact of three sources of error on accuracy and precision, including different operators, instruments, and calibration standards, was evaluated using a broadband reflectance standard and two different solid tissue-simulating optical phantoms. Instruments showed <0.0010 mm-1 (10.3%) and 0.06 mm-1 (4.7%) deviation in broadband absorption and reduced scattering, respectively, over the 2-year duration of ACRIN-6691. These variations establish a useful performance criterion for assessing instrument stability. The proposed procedures and tests are not limited to DOSI; rather, they are intended to provide methods to characterize performance of any instrument used in translational optical imaging.

  11. Multi-wavelength imaging of solar plasma. High-beta disruption model of solar flares

    Shibasaki, Kiyoto

    2007-01-01

    Solar atmosphere is filled with plasma and magnetic field. Activities in the atmosphere are due to plasma instabilities in the magnetic field. To understand the physical mechanisms of activities / instabilities, it is necessary to know the physical conditions of magnetized plasma, such as temperature, density, magnetic field, and their spatial structures and temporal developments. Multi-wavelength imaging is essential for this purpose. Imaging observations of the Sun at microwave, X-ray, EUV and optical ranges are routinely going on. Due to free exchange of original data among solar physics and related field communities, we can easily combine images covering wide range of spectrum. Even under such circumstances, we still do not understand the cause of activities in the solar atmosphere well. The current standard model of solar activities is based on magnetic reconnection: release of stored magnetic energy by reconnection is the cause of solar activities on the Sun such as solar flares. However, recent X-ray, EUV and microwave observations with high spatial and temporal resolution show that dense plasma is involved in activities from the beginning. Based on these observations, I propose a high-beta model of solar activities, which is very similar to high-beta disruptions in magnetically confined fusion experiments. (author)

  12. Flying-spot analysis of solar images

    Azzarelli, L.; Carlesi, C.; Panicucci, R.; Falciani, R.; Giordano, M.; Rigutti, M.; Roberti, G.

    1975-01-01

    This work has been performed to test the new results obtained previously with a photographic isodensitometric method about the photometric evolution of solar flares and to study the degree of utility and reliability and the general performances of high speed, computer controlled devices in the photometric analysis of extended sources. Some series of good Hα solar filter grams, obtained during 1969 (May 15-16-17-25 and Oct 25-27), at the Athens National Observatory, with time resolution of about 30 sec, with uniform exposure and high photometric accuracy (approximately 5000 filtergrams) are studied. (Auth.)

  13. Imaging capabilities of SXT for Solar-A

    Lemen, J. R.; Acton, L. W.; Brown, W. A.; Bruner, M. E.; Catura, R. C.

    1991-01-01

    The present study characterizes the Soft X-ray Telescope (SXT), a grazing-incidence solar X-ray telescope which will be flown on the Japanese Solar-A satellite. X-ray tests showed that the SXT mirror meets or exceeds design requirements. SXT advantages over Skylab are: improved time resolution (not less than 0.5 s), greatly decreased mirror scatter, coaligned aspect telescope to intersperse images of sunspots and magnetic plage, and digital data readout.

  14. Confocal spectroscopic imaging measurements of depth dependent hydration dynamics in human skin in-vivo

    Behm, P.; Hashemi, M.; Hoppe, S.; Wessel, S.; Hagens, R.; Jaspers, S.; Wenck, H.; Rübhausen, M.

    2017-11-01

    We present confocal spectroscopic imaging measurements applied to in-vivo studies to determine the depth dependent hydration profiles of human skin. The observed spectroscopic signal covers the spectral range from 810 nm to 2100 nm allowing to probe relevant absorption signals that can be associated with e.g. lipid and water-absorption bands. We employ a spectrally sensitive autofocus mechanism that allows an ultrafast focusing of the measurement spot on the skin and subsequently probes the evolution of the absorption bands as a function of depth. We determine the change of the water concentration in m%. The water concentration follows a sigmoidal behavior with an increase of the water content of about 70% within 5 μm in a depth of about 14 μm. We have applied our technique to study the hydration dynamics of skin before and after treatment with different concentrations of glycerol indicating that an increase of the glycerol concentration leads to an enhanced water concentration in the stratum corneum. Moreover, in contrast to traditional corneometry we have found that the application of Aluminium Chlorohydrate has no impact to the hydration of skin.

  15. Confocal spectroscopic imaging measurements of depth dependent hydration dynamics in human skin in-vivo

    P. Behm

    2017-11-01

    Full Text Available We present confocal spectroscopic imaging measurements applied to in-vivo studies to determine the depth dependent hydration profiles of human skin. The observed spectroscopic signal covers the spectral range from 810 nm to 2100 nm allowing to probe relevant absorption signals that can be associated with e.g. lipid and water-absorption bands. We employ a spectrally sensitive autofocus mechanism that allows an ultrafast focusing of the measurement spot on the skin and subsequently probes the evolution of the absorption bands as a function of depth. We determine the change of the water concentration in m%. The water concentration follows a sigmoidal behavior with an increase of the water content of about 70% within 5 μm in a depth of about 14 μm. We have applied our technique to study the hydration dynamics of skin before and after treatment with different concentrations of glycerol indicating that an increase of the glycerol concentration leads to an enhanced water concentration in the stratum corneum. Moreover, in contrast to traditional corneometry we have found that the application of Aluminium Chlorohydrate has no impact to the hydration of skin.

  16. GREGOR Fabry-Pérot interferometer and its companion the blue imaging solar spectrometer

    Puschmann, Klaus G.; Denker, Carsten; Balthasar, Horst; Louis, Rohan E.; Popow, Emil; Woche, Manfred; Beck, Christian; Seelemann, Thomas; Volkmer, Reiner

    2013-08-01

    The GREGOR Fabry-Pérot Interferometer (GFPI) is one of three first-light instruments of the German 1.5-m GREGOR solar telescope at the Observatorio del Teide, Tenerife, Spain. The GFPI allows fast narrow-band imaging and postfactum image restoration. The retrieved physical parameters will be a fundamental building block for understanding the dynamic sun and its magnetic field at spatial scales down to ˜50 km on the solar surface. The GFPI is a tunable dual-etalon system in a collimated mounting. It is designed for spectrometric and spectropolarimetric observations between 530-860 nm and 580-660 nm, respectively, and possesses a theoretical spectral resolution of R≈250,000. Large-format, high-cadence charged coupled device detectors with sophisticated computer hard- and software enable the scanning of spectral lines in time-spans equivalent to the evolution time of solar features. The field-of-view (FOV) of 50″×38″ covers a significant fraction of the typical area of active regions in the spectroscopic mode. In case of Stokes-vector spectropolarimetry, the FOV reduces to 25″×38″. The main characteristics of the GFPI including advanced and automated calibration and observing procedures are presented. Improvements in the optical design of the instrument are discussed and first observational results are shown. Finally, the first concrete ideas for the integration of a second FPI, the blue imaging solar spectrometer, are laid out, which will explore the blue spectral region below 530 nm.

  17. FT-IR spectroscopic imaging of reactions in multiphase flow in microfluidic channels.

    Chan, K L Andrew; Kazarian, Sergei G

    2012-05-01

    Rapid, in situ, and label-free chemical analysis in microfluidic devices is highly desirable. FT-IR spectroscopic imaging has previously been shown to be a powerful tool to visualize the distribution of different chemicals in flows in a microfluidic device at near video rate imaging speed without tracers or dyes. This paper demonstrates the possibility of using this imaging technology to capture the chemical information of all reactants and products at different points in time and space in a two-phase system. Differences in the rates of chemical reactions in laminar flow and segmented flow systems are also compared. Neutralization of benzoic acid in decanol with disodium phosphate in water has been used as the model reaction. Quantitative information, such as concentration profiles of reactant and products, can be extracted from the imaging data. The same feed flow rate was used in both the laminar flow and segmented flow systems. The laminar flow pattern was achieved using a plain wide T-junction, whereas the segmented flow was achieved by introducing a narrowed section and a nozzle at the T-junction. The results show that the reaction rate is limited by diffusion and is much slower with the laminar flow pattern, whereas the reaction is completed more quickly in the segmented flow due to better mixing.

  18. Book Review: Reiner Salzer and Heinz W. Siesler (Eds.): Infrared and Raman spectroscopic imaging, 2nd ed

    Moore, David Steven

    2015-01-01

    This second edition of 'Infrared and Raman Spectroscopic Imaging' propels practitioners in that wide-ranging field, as well as other readers, to the current state of the art in a well-produced and full-color, completely revised and updated, volume. This new edition chronicles the expanded application of vibrational spectroscopic imaging from yesterday's time-consuming point-by-point buildup of a hyperspectral image cube, through the improvements afforded by the addition of focal plane arrays and line scan imaging, to methods applicable beyond the diffraction limit, instructs the reader on the improved instrumentation and image and data analysis methods, and expounds on their application to fundamental biomedical knowledge, food and agricultural surveys, materials science, process and quality control, and many others

  19. Construction and performance of a dilution-refrigerator based spectroscopic-imaging scanning tunneling microscope.

    Singh, U R; Enayat, M; White, S C; Wahl, P

    2013-01-01

    We report on the set-up and performance of a dilution-refrigerator based spectroscopic imaging scanning tunneling microscope. It operates at temperatures below 10 mK and in magnetic fields up to 14T. The system allows for sample transfer and in situ cleavage. We present first-results demonstrating atomic resolution and the multi-gap structure of the superconducting gap of NbSe(2) at base temperature. To determine the energy resolution of our system we have measured a normal metal/vacuum/superconductor tunneling junction consisting of an aluminum tip on a gold sample. Our system allows for continuous measurements at base temperature on time scales of up to ≈170 h.

  20. Time-resolved spectroscopic imaging reveals the fundamentals of cellular NADH fluorescence.

    Li, Dong; Zheng, Wei; Qu, Jianan Y

    2008-10-15

    A time-resolved spectroscopic imaging system is built to study the fluorescence characteristics of nicotinamide adenine dinucleotide (NADH), an important metabolic coenzyme and endogenous fluorophore in cells. The system provides a unique approach to measure fluorescence signals in different cellular organelles and cytoplasm. The ratios of free over protein-bound NADH signals in cytosol and nucleus are slightly higher than those in mitochondria. The mitochondrial fluorescence contributes about 70% of overall cellular fluorescence and is not a completely dominant signal. Furthermore, NADH signals in mitochondria, cytosol, and the nucleus respond to the changes of cellular activity differently, suggesting that cytosolic and nuclear fluorescence may complicate the well-known relationship between mitochondrial fluorescence and cellular metabolism.

  1. Principal component and spatial correlation analysis of spectroscopic-imaging data in scanning probe microscopy

    Jesse, Stephen; Kalinin, Sergei V

    2009-01-01

    An approach for the analysis of multi-dimensional, spectroscopic-imaging data based on principal component analysis (PCA) is explored. PCA selects and ranks relevant response components based on variance within the data. It is shown that for examples with small relative variations between spectra, the first few PCA components closely coincide with results obtained using model fitting, and this is achieved at rates approximately four orders of magnitude faster. For cases with strong response variations, PCA allows an effective approach to rapidly process, de-noise, and compress data. The prospects for PCA combined with correlation function analysis of component maps as a universal tool for data analysis and representation in microscopy are discussed.

  2. A Restrospective and Prospective Examination of NOAA Solar Imaging

    Hill, S. M.

    2015-12-01

    NOAA has provided soft X-ray imaging of the lower corona since the early 2000's. It is currently building the spacecraft and instrumentation to observe the sun in the extreme ultraviolet (EUV) through 2036. After more than 6 million calibrated images, it is appropriate to examine NOAA data as providing retrospective context for scientific missions. In particular, this presentation examines the record of GOES Solar X-ray Imager (SXI) observations, including continuity, photometric stability and comparison to other contemporary x-ray imagers. The first GOES Solar X-ray Imager was launched in 2001 and entered operations in 2003. The current SXIs will remain in operations until approximately 2020, when a new series of Solar (extreme-)Ultraviolet Imagers (SUVIs) will replace them as the current satellites reach their end of life. In the sense that the SXIs are similar to Yokoh's SXT and Hinode's XRT, the SUVI instruments will be similar to SOHO's EIT and SDO's AIA. The move to narrowband EUV imagers will better support eventual operational estimation of plasma conditions. In particular, plans are to leverage advances in automated image processing and segmentation to assist forecasters. While NOAA's principal use of these observations is real-time space weather forecasting, they will continue to provide a consistent context measurement for researchers for decades to come.

  3. The hippocampus in patients treated with electroconvulsive therapy: a proton magnetic resonance spectroscopic imaging study.

    Ende, G; Braus, D F; Walter, S; Weber-Fahr, W; Henn, F A

    2000-10-01

    We monitored the effect of electroconvulsive therapy (ECT) on the nuclear magnetic resonance-detectable metabolites N-acetylaspartate, creatine and phosphocreatine, and choline-containing compounds in the hippocampus by means of hydrogen 1 magnetic resonance spectroscopic imaging. We hypothesized that if ECT-induced memory deterioration was associated with neuronal loss in the hippocampus, the N-acetylaspartate signal would decrease after ECT and any increased membrane turnover would result in an increase in the signal from choline-containing compounds. Seventeen patients received complete courses of ECT, during which repeated proton magnetic resonance spectroscopic imaging studies of the hippocampal region were performed. Individual changes during the course of ECT were compared with values obtained in 24 healthy control subjects and 6 patients remitted from major depression without ECT. No changes in the hippocampal N-acetylaspartate signals were detected after ECT. A significant mean increase of 16% of the signal from choline-containing compounds after 5 or more ECT treatments was observed. Despite the mostly unilateral ECT application (14 of 17 patients), the increase in the choline-containing compound signal was observed bilaterally. Lactate or elevated lipid signals were not detected. All patients showed clinical amelioration of depression after ECT. Electroconvulsive therapy is not likely to induce hippocampal atrophy or cell death, which would be reflected by a decrease in the N-acetylaspartate signal. Compared with an age-matched control group, the choline-containing compounds signal in patients with a major depressive episode was significantly lower than normal, before ECT and normalized during ECT.

  4. Accelerated high-resolution 3D magnetic resonance spectroscopic imaging in the brain At 7 T

    Hangel, G.

    2015-01-01

    With the announcement of the first series of magnetic resonance (MR) scanners with a field strength of 7 Tesla (T) intended for clinical practice, the development of high-performance sequences for higher field strengths has gained importance. Magnetic resonance spectroscopic imaging (MRSI) in the brain currently offers the unique ability to spatially resolve the distribution of multiple metabolites simultaneously. Its big diagnostic potential could be applied to many clinical protocols, for example the assessment of tumour treatment or progress of Multiple Sclerosis. Moving to ultra-high fields like 7 T has the main benefits of increased signal-to-noise ratio (SNR) and improved spectral quality, but brings its own challenges due to stronger field inhomogeneities. Necessary for a robust, flexible and useful MRSI sequence in the brain are high resolutions, shortened measurement times, the possibility for 3D-MRSI and the suppression of spectral contamination by trans-cranial lipids. This thesis addresses these limitations and proposes Hadamard spectroscopic imaging (HSI) as solution for multi-slice MRSI, the application of generalized autocalibrating partially parallel acquisition (GRAPPA) and spiral trajectories for measurement acceleration, non-selective inversion recovery (IR) lipid-suppression as well as combinations of these methods. Further, the optimisation of water suppression for 7 T systems and the acquisition of ultra-high resolution (UHR)-MRSI are discussed. In order to demonstrate the clinical feasibility of these approaches, MRSI measurement results of a glioma patient are presented. The discussion of the obtained results in the context of the state-of-art in 7 T MRSI in the brain, possible future applications as well as potential further improvements of the MRSI sequences conclude this thesis. (author) [de

  5. Aberration-free FTIR spectroscopic imaging of live cells in microfluidic devices.

    Chan, K L Andrew; Kazarian, Sergei G

    2013-07-21

    The label-free, non-destructive chemical analysis offered by FTIR spectroscopic imaging is a very attractive and potentially powerful tool for studies of live biological cells. FTIR imaging of live cells is a challenging task, due to the fact that cells are cultured in an aqueous environment. While the synchrotron facility has proven to be a valuable tool for FTIR microspectroscopic studies of single live cells, we have demonstrated that high quality infrared spectra of single live cells using an ordinary Globar source can also be obtained by adding a pair of lenses to a common transmission liquid cell. The lenses, when placed on the transmission cell window, form pseudo hemispheres which removes the refraction of light and hence improve the imaging and spectral quality of the obtained data. This study demonstrates that infrared spectra of single live cells can be obtained without the focus shifting effect at different wavenumbers, caused by the chromatic aberration. Spectra of the single cells have confirmed that the measured spectral region remains in focus across the whole range, while spectra of the single cells measured without the lenses have shown some erroneous features as a result of the shift of focus. It has also been demonstrated that the addition of lenses can be applied to the imaging of cells in microfabricated devices. We have shown that it was not possible to obtain a focused image of an isolated cell in a droplet of DPBS in oil unless the lenses are applied. The use of the approach described herein allows for well focused images of single cells in DPBS droplets to be obtained.

  6. Spectroscopic Studies of Solar Corona VI: Trend in Line-width ...

    cm coronagraph at the Norikura Solar Observatory on several days during the years 1997–2004. The Coude type .... Top-most panel shows the variation of FWHM of the 6374 Е and 5303 Е emission lines with height above the limb when all ...

  7. Spectroscopic and impedance studies of reverse biased degraded dye solar cells

    Le Roux, Lukas J

    2011-03-01

    Full Text Available The work that is presented here is focused on the results that were obtained during studies of the performance of Dye Solar Cells under certain reverse bias conditions. This reverse voltage could permanently modify or damage a cell...

  8. Regional neuro axonal injury detected by 1H 3 Tesla spectroscopic imaging in late onset Tay sachs

    Gagoski, Borjan Aleksandar; Eichler, Florian S.

    2010-01-01

    Late-onset Tay Sachs (LOTS) is a rare lysosomal storage disorder resulting from mutations of the subunit of the lysosomal enzyme β-hexosaminidase A, which catalyzes the degradation of GM2 ganglioside. We have applied the fast encoding spectroscopic imaging technique to LOTS patients to further investigate the neuro degenerative consequences of this disease.(Author)

  9. Three-dimensional proton magnetic resonance spectroscopic imaging with and without an endorectal coil: a prostate phantom study

    Ma, C.; Chen, L.; Scheenen, T.W.J.; Lu, J.; Wang, J

    2015-01-01

    Proton magnetic resonance spectroscopic imaging (MRSI) of the prostate has been used with only a combination of external surface coils. The quality of spectral fitting of the (choline + creatine)/citrate ([Cho + Cr]/Cit) ratio at different field strengths and different coils is important for

  10. Image dissector photocathode solar damage test program. [solar radiation shielding using a fast optical lens

    Smith, R. A.

    1977-01-01

    Image dissector sensors of the same type which will be used in the NASA shuttle star tracker were used in a series of tests directed towards obtaining solar radiation/time damage criteria. Data were evaluated to determine the predicted level of operability of the star tracker if tube damage became a reality. During the test series a technique for reducing the solar damage effect was conceived and verified. The damage concepts are outlined and the test methods and data obtained which were used for verification of the technique's feasibility are presented. The ability to operate an image dissector sensor with the solar image focussed on the photocathode by a fast optical lens under certain conditions is feasible and the elimination of a mechanical protection device is possible.

  11. SDSS-III: MASSIVE SPECTROSCOPIC SURVEYS OF THE DISTANT UNIVERSE, THE MILKY WAY, AND EXTRA-SOLAR PLANETARY SYSTEMS

    Eisenstein, Daniel J.; Weinberg, David H.; Agol, Eric; Anderson, Scott F.; Aihara, Hiroaki; Allende Prieto, Carlos; Arns, James A.; Aubourg, Eric; Bailey, Stephen; Balbinot, Eduardo; Barkhouser, Robert; Beers, Timothy C.; Berlind, Andreas A.; Bickerton, Steven J.; Bizyaev, Dmitry; Blanton, Michael R.; Bochanski, John J.; Bolton, Adam S.

    2011-01-01

    Building on the legacy of the Sloan Digital Sky Survey (SDSS-I and II), SDSS-III is a program of four spectroscopic surveys on three scientific themes: dark energy and cosmological parameters, the history and structure of the Milky Way, and the population of giant planets around other stars. In keeping with SDSS tradition, SDSS-III will provide regular public releases of all its data, beginning with SDSS Data Release 8 (DR8), which was made public in 2011 January and includes SDSS-I and SDSS-II images and spectra reprocessed with the latest pipelines and calibrations produced for the SDSS-III investigations. This paper presents an overview of the four surveys that comprise SDSS-III. The Baryon Oscillation Spectroscopic Survey will measure redshifts of 1.5 million massive galaxies and Lyα forest spectra of 150,000 quasars, using the baryon acoustic oscillation feature of large-scale structure to obtain percent-level determinations of the distance scale and Hubble expansion rate at z 5 evolved, late-type stars, measuring separate abundances for ∼15 elements per star and creating the first high-precision spectroscopic survey of all Galactic stellar populations (bulge, bar, disks, halo) with a uniform set of stellar tracers and spectral diagnostics. The Multi-object APO Radial Velocity Exoplanet Large-area Survey (MARVELS) will monitor radial velocities of more than 8000 FGK stars with the sensitivity and cadence (10-40 m s -1 , ∼24 visits per star) needed to detect giant planets with periods up to two years, providing an unprecedented data set for understanding the formation and dynamical evolution of giant planet systems. As of 2011 January, SDSS-III has obtained spectra of more than 240,000 galaxies, 29,000 z ≥ 2.2 quasars, and 140,000 stars, including 74,000 velocity measurements of 2580 stars for MARVELS.

  12. Imaging properties of small-pixel spectroscopic x-ray detectors based on cadmium telluride sensors

    Koenig, Thomas; Schulze, Julia; Zuber, Marcus; Rink, Kristian; Oelfke, Uwe; Butzer, Jochen; Hamann, Elias; Cecilia, Angelica; Zwerger, Andreas; Fauler, Alex; Fiederle, Michael

    2012-01-01

    Spectroscopic x-ray imaging by means of photon counting detectors has received growing interest during the past years. Critical to the image quality of such devices is their pixel pitch and the sensor material employed. This paper describes the imaging properties of Medipix2 MXR multi-chip assemblies bump bonded to 1 mm thick CdTe sensors. Two systems were investigated with pixel pitches of 110 and 165 μm, which are in the order of the mean free path lengths of the characteristic x-rays produced in their sensors. Peak widths were found to be almost constant across the energy range of 10 to 60 keV, with values of 2.3 and 2.2 keV (FWHM) for the two pixel pitches. The average number of pixels responding to a single incoming photon are about 1.85 and 1.45 at 60 keV, amounting to detective quantum efficiencies of 0.77 and 0.84 at a spatial frequency of zero. Energy selective CT acquisitions are presented, and the two pixel pitches' abilities to discriminate between iodine and gadolinium contrast agents are examined. It is shown that the choice of the pixel pitch translates into a minimum contrast agent concentration for which material discrimination is still possible. We finally investigate saturation effects at high x-ray fluxes and conclude with the finding that higher maximum count rates come at the cost of a reduced energy resolution. (paper)

  13. In vivo, noninvasive functional measurements of bone sarcoma using diffuse optical spectroscopic imaging

    Peterson, Hannah M.; Hoang, Bang H.; Geller, David; Yang, Rui; Gorlick, Richard; Berger, Jeremy; Tingling, Janet; Roth, Michael; Gill, Jonathon; Roblyer, Darren

    2017-12-01

    Diffuse optical spectroscopic imaging (DOSI) is an emerging near-infrared imaging technique that noninvasively measures quantitative functional information in thick tissue. This study aimed to assess the feasibility of using DOSI to measure optical contrast from bone sarcomas. These tumors are rare and pose technical and practical challenges for DOSI measurements due to the varied anatomic locations and tissue depths of presentation. Six subjects were enrolled in the study. One subject was unable to be measured due to tissue contact sensitivity. For the five remaining subjects, the signal-to-noise ratio, imaging depth, optical properties, and quantitative tissue concentrations of oxyhemoglobin, deoxyhemoglobin, water, and lipids from tumor and contralateral normal tissues were assessed. Statistical differences between tumor and contralateral normal tissue were found in chromophore concentrations and optical properties for four subjects. Low signal-to-noise was encountered during several subject's measurements, suggesting increased detector sensitivity will help to optimize DOSI for this patient population going forward. This study demonstrates that DOSI is capable of measuring optical properties and obtaining functional information in bone sarcomas. In the future, DOSI may provide a means to stratify treatment groups and monitor chemotherapy response for this disease.

  14. Development of a spectroscopic Mueller matrix imaging ellipsometer for nanostructure metrology

    Chen, Xiuguo; Du, Weichao; Yuan, Kui; Chen, Jun; Jiang, Hao; Zhang, Chuanwei; Liu, Shiyuan

    2016-01-01

    In this paper, we describe the development of a spectroscopic Mueller matrix imaging ellipsometer (MMIE), which combines the great power of Mueller matrix ellipsometry with the high spatial resolution of optical microscopy. A dual rotating-compensator configuration is adopted to collect the full 4 × 4 imaging Mueller matrix in a single measurement. The light wavelengths are scanned in the range of 400–700 nm by a monochromator. The instrument has measurement accuracy and precision better than 0.01 for all the Mueller matrix elements in both the whole image and the whole spectral range. The instrument was then applied for the measurement of nanostructures combined with an inverse diffraction problem solving technique. The experiment performed on a photoresist grating sample has demonstrated the great potential of MMIE for accurate grating reconstruction from spectral data collected by a single pixel of the camera and for efficient quantification of geometrical profile of the grating structure over a large area with pixel resolution. It is expected that MMIE will be a powerful tool for nanostructure metrology in future high-volume nanomanufacturing.

  15. Development of a spectroscopic Mueller matrix imaging ellipsometer for nanostructure metrology

    Chen, Xiuguo; Du, Weichao; Yuan, Kui; Chen, Jun; Jiang, Hao, E-mail: hjiang@hust.edu.cn [State Key Laboratory of Digital Manufacturing Equipment and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); Zhang, Chuanwei; Liu, Shiyuan, E-mail: hjiang@hust.edu.cn [State Key Laboratory of Digital Manufacturing Equipment and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); Wuhan Eoptics Technology Co. Ltd., Wuhan 430075 (China)

    2016-05-15

    In this paper, we describe the development of a spectroscopic Mueller matrix imaging ellipsometer (MMIE), which combines the great power of Mueller matrix ellipsometry with the high spatial resolution of optical microscopy. A dual rotating-compensator configuration is adopted to collect the full 4 × 4 imaging Mueller matrix in a single measurement. The light wavelengths are scanned in the range of 400–700 nm by a monochromator. The instrument has measurement accuracy and precision better than 0.01 for all the Mueller matrix elements in both the whole image and the whole spectral range. The instrument was then applied for the measurement of nanostructures combined with an inverse diffraction problem solving technique. The experiment performed on a photoresist grating sample has demonstrated the great potential of MMIE for accurate grating reconstruction from spectral data collected by a single pixel of the camera and for efficient quantification of geometrical profile of the grating structure over a large area with pixel resolution. It is expected that MMIE will be a powerful tool for nanostructure metrology in future high-volume nanomanufacturing.

  16. SDSS-III: Massive Spectroscopic Surveys of the Distant Universe, the Milky Way Galaxy, and Extra-Solar Planetary Systems

    Eisenstein, Daniel J.; /Arizona U., Astron. Dept. - Steward Observ. /Harvard U., Phys. Dept.; Weinberg, David H.; /Ohio State U.; Agol, Eric; /Washington U., Seattle, Astron. Dept.; Aihara, Hiroaki; /Tokyo U.; Prieto, Carlos Allende; /Laguna U., Tenerife; Anderson, Scott F.; /Washington U., Seattle, Astron. Dept.; Arns, James A.; /Michigan U.; Aubourg, Eric; /APC, Paris /DAPNIA, Saclay; Bailey, Stephen; /LBL, Berkeley; Balbinot, Eduardo; /Rio Grande do Sul U. /Rio de Janeiro Observ.; Barkhouser, Robert; /Johns Hopkins U. /Michigan State U.

    2011-01-01

    Building on the legacy of the Sloan Digital Sky Survey (SDSS-I and II), SDSS-III is a program of four spectroscopic surveys on three scientific themes: dark energy and cosmological parameters, the history and structure of the Milky Way, and the population of giant planets around other stars. The Baryon Oscillation Spectroscopic Survey (BOSS) will measure redshifts of 1.5 million massive galaxies and Ly{alpha} forest spectra of 150,000 quasars, using the baryon acoustic oscillation (BAO) feature of large scale structure to obtain percent-level determinations of the distance scale and Hubble expansion rate at z < 0.7 and at z {approx} 2.5. SEGUE-2, a now-completed continuation of the Sloan Extension for Galactic Understanding and Exploration, measured medium-resolution (R = {lambda}/{Delta}{lambda} 1800) optical spectra of 118,000 stars in a variety of target categories, probing chemical evolution, stellar kinematics and substructure, and the mass profile of the dark matter halo from the solar neighborhood to distances of 100 kpc. APOGEE, the Apache Point Observatory Galactic Evolution Experiment, will obtain high-resolution (R {approx} 30,000), high signal-to-noise ratio (S/N {ge} 100 per resolution element), H-band (1.51 {micro}m < {lambda} < 1.70 {micro}m) spectra of 10{sup 5} evolved, late-type stars, measuring separate abundances for {approx} 15 elements per star and creating the first high-precision spectroscopic survey of all Galactic stellar populations (bulge, bar, disks, halo) with a uniform set of stellar tracers and spectral diagnostics. The Multi-object APO Radial Velocity Large-area Survey (MARVELS) will monitor radial velocities of more than 8000 FGK stars with the sensitivity and cadence (10-40 m s{sup -1}, {approx} 24 visits per star) needed to detect giant planets with periods up to two years, providing an unprecedented data set for understanding the formation and dynamical evolution of giant planet systems. As of January 2011, SDSS-III has obtained

  17. Automatic solar image motion measurements. [electronic disk flux monitoring

    Colgate, S. A.; Moore, E. P.

    1975-01-01

    The solar seeing image motion has been monitored electronically and absolutely with a 25 cm telescope at three sites along the ridge at the southern end of the Magdalena Mountains west of Socorro, New Mexico. The uncorrelated component of the variations of the optical flux from two points at opposite limbs of the solar disk was continually monitored in 3 frequencies centered at 0.3, 3 and 30 Hz. The frequency band of maximum signal centered at 3 Hz showed the average absolute value of image motion to be somewhat less than 2sec. The observer estimates of combined blurring and image motion were well correlated with electronically measured image motion, but the observer estimates gave a factor 2 larger value.

  18. Spectroscopic, scanning laser OBIC, and I-V/QE characterizations of browned EVA solar cells

    Pern, F.J. [National Renewable Energy Lab., Golden, CO (United States); Eisgruber, I.L. [Materials Research Group, Inc., Wheat Ridge, CO (United States); Micheels, R.H. [Polestar Technologies, Inc., Needham Hts, MA (United States)

    1996-05-01

    The effects of ethylene-vinyl acetate (EVA) discoloration due to accelerated field or laboratory exposure on the encapsulated silicon (Si) solar cells or EVA/glass laminates were characterized quantitatively by using non-invasive, non-destructive ultraviolet-visible (UV-vis) spectrophotometry, spectrocolorimetry, spectrofluorometry, scanning laser OBIC (optical beam induced current) spectroscopy, and current-voltage (I-V) and quantum efficiency (QE) measurements. The results show that the yellowness index (YI) measured directly over the AR-coated solar cells under the glass superstrate increased from the range of -80 to -90 to the range of -20 to 15 as the EVA changed from clear to brown. The ratio of two fluorescence emission peak areas generally increased from 1.45 to 5.69 as browning increased, but dropped to 4.21 on a darker EVA. For a solar cell with brown EVA in the central region, small-area grating QE measurements and scanning laser OBIC analysis between the brown and clear EVA regions showed that the quantum efficiency loss at 633 nm was 42%-48% of the loss at 488 nm, due to a reduced decrease of transmittance in browned EVA at the longer wavelengths. The portion of the solar cell under the browned EVA showed a decrease of {approximately}36% in efficiency, as compared to the cell efficiency under clear EVA. Transmittance loss at 633 nm was 38% of the loss at 488 nm for a light yellow-brown EVA/glass laminate that showed a small increase of 10 in the yellowness index.

  19. Attenuated total reflectance Fourier-transform infrared spectroscopic investigation of silicon heterojunction solar cells

    Holovský, Jakub; De Wolf, S.; Jiříček, Petr; Ballif, C.

    2015-01-01

    Roč. 86, č. 7 (2015), , "073108-1"-"073108-6" ISSN 0034-6748 R&D Projects: GA ČR(CZ) GA14-05053S; GA MŠk 7E12029; GA MŠk(CZ) LM2011026 EU Projects: European Commission(XE) 283501 - Fast Track Institutional support: RVO:68378271 Keywords : FTIR * ATR * solar cells Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.336, year: 2015

  20. FIRST IMAGES FROM THE FOCUSING OPTICS X-RAY SOLAR IMAGER

    Krucker, Säm; Glesener, Lindsay; Turin, Paul; McBride, Stephen; Glaser, David; Fermin, Jose; Lin, Robert [Space Sciences Laboratory, University of California at Berkeley, Berkeley, CA (United States); Christe, Steven [NASA Goddard Space Flight Center, Greenbelt, MD (United States); Ishikawa, Shin-nosuke [National Astronomical Observatory, Mitaka (Japan); Ramsey, Brian; Gubarev, Mikhail; Kilaru, Kiranmayee [NASA Marshall Space Flight Center, Huntsville, AL (United States); Takahashi, Tadayuki; Watanabe, Shin; Saito, Shinya [Institute of Space and Astronautical Science (ISAS)/JAXA, Sagamihara (Japan); Tajima, Hiroyasu [Solar-Terrestial Environment Laboratory, Nagoya University, Nagoya (Japan); Tanaka, Takaaki [Department of Physics, Kyoto University, Kyoto (Japan); White, Stephen [Air Force Research Laboratory, Albuquerque, NM (United States)

    2014-10-01

    The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload flew for the first time on 2012 November 2, producing the first focused images of the Sun above 5 keV. To enable hard X-ray (HXR) imaging spectroscopy via direct focusing, FOXSI makes use of grazing-incidence replicated optics combined with fine-pitch solid-state detectors. On its first flight, FOXSI observed several targets that included active regions, the quiet Sun, and a GOES-class B2.7 microflare. This Letter provides an introduction to the FOXSI instrument and presents its first solar image. These data demonstrate the superiority in sensitivity and dynamic range that is achievable with a direct HXR imager with respect to previous, indirect imaging methods, and illustrate the technological readiness for a spaceborne mission to observe HXRs from solar flares via direct focusing optics.

  1. Adaptive image stabilization of solar observations: A review

    Von Der Luhe, O.

    1985-01-01

    The purpose of this contribution is to review recent developments of active wave front correction techniques for solar imaging. Experience has shown, that image motion control significantly improves the resolution of typical long exposure applications such as spectrograms and spectroheliograms. Basic IM control systems need only simple technology and, in most cases, are easily implemented in most existing telescopes. Spot trackers are on their way to being routineously used

  2. Local helioseismology: three-dimensional imaging of the solar interior

    Gizon, L.; Birch, A.C.; Spruit, H.C.

    2010-01-01

    The Sun supports a rich spectrum of internal waves that are continuously excited by turbulent convection. The Global Oscillation Network Group (GONG) network and the SOHO/MDI (Solar and Heliospheric Observatory/Michelson Doppler Imager) space instrument provide an exceptional database of spatially

  3. Quantifying Solar Cell Cracks in Photovoltaic Modules by Electroluminescence Imaging

    Spataru, Sergiu; Hacke, Peter; Sera, Dezso

    2015-01-01

    This article proposes a method for quantifying the percentage of partially and totally disconnected solar cell cracks by analyzing electroluminescence images of the photovoltaic module taken under high- and low-current forward bias. The method is based on the analysis of the module’s electrolumin...

  4. Trends in NOAA Solar X-ray Imager Performance

    Hill, Steven M.; Darnell, John A.; Seaton, Daniel B.

    2016-05-01

    NOAA has provided operational soft X-ray imaging of the sun since the early 2000’s. After 15 years of observations by four different telescopes, it is appropriate to examine the data in terms of providing consistent context for scientific missions. In particular, this presentation examines over 7 million GOES Solar X-ray Imager (SXI) images for trends in performance parameters including dark current, response degradation, and inter-calibration. Because observations from the instrument have overlapped not only with each other, but also with research observations like Yohkoh SXT and Hinode XRT, relative performance comparisons can be made. The first GOES Solar X-ray Imager was launched in 2001 and entered operations in 2003. The current SXIs will remain in operations until approximately 2020, when a new series of Solar (extreme-)Ultraviolet Imagers (SUVIs) will replace them as the current satellites reach their end of life. In the sense that the SXIs are similar to Yokoh’s SXT and Hinode’s XRT, the SUVI instruments will be similar to SOHO’s EIT and SDO’s AIA. The move to narrowband EUV imagers will better support eventual operational estimation of plasma conditions. While NOAA’s principal use of these observations is real-time space weather forecasting, they will continue to provide a reliable context measurement for researchers for decades to come.

  5. Localised proton spectroscopy and spectroscopic imaging in cerebral gliomas, with comparison to positron emission tomography

    Go, K.G.; Kamman, R.L.; Mooyaart, E.L.; Heesters, M.A.A.M.; Pruim, J.; Vaalburg, W.; Paans, A.M.J.

    1995-01-01

    In 32 patients with gliomas, one- and two-dimensional proton magnetic resonance spectroscopy ( 1 H-MRS) has been conducted, the latter allowing reconstruction of spectroscopic data into a spectroscopic image (MRSI), showing the distribution of the various metabolite concentrations over the cross-sectional plane. For lack of absolute concentrations, the measured concentrations of phosphocholine (CHOL), N-acetyl-L-aspartate (NAA), and lactate (LAC) were conventionally expressed in ratios relative to that of creatine (CREAT). Compared to normal brain tissue, an increased CHOL/CREAT ratio was found in all groups of tumours, in glioblastomas, high-, middle- and low-grade astrocytomas both at the margin and the core of the tumours, but in oligodendrogliomas only at the margin. This is consistent with an increased phosphocholine turnover in relation to membrane biosynthesis by the proliferating cells. The NAA/CREAT ratio was decreased in all groups of tumours, both in the centre and at the margin, reflecting replacement of functioning neurons by neoplastic cells. The LAC/CREAT ratio was elevated in the core of malignant gliomas, which may be the result of a prevailing glycolysis, characteristic of tumours, possibly in conjunction with hypoxia/ischaemia. In the perifocal oedema, there was neither elevation of the CHOL/CREAT ratio nor decrease of the NAA/CREAT ratio; an increased LAC/CREAT ratio therefore rather reflected ischaemia/hypoxia probably due to locally elevated pressure and compromised regional perfusion. In the normal brain, the metabolite ratios of grey matter did not differ from those of white matter. The frontal lobe and basal ganglia showed lower NAA/CREAT ratios than the other cerebral areas. In 7 patients positron emission tomography was also performed with [ 18 F]fluoro-2-deoxy-D-glucose ( 18 FDG) or L-[1- 11 C]-tyrosine ( 11 C-TYR); the latter demonstrated a pattern of 11 C-TYR uptake similar to that of CHOL elevation in the MRSI. (orig.)

  6. Proton MR spectroscopic imaging of basal ganglia and thalamus in neurofibromatosis type 1: correlation with T2 hyperintensities

    Barbier, Charlotte; Barantin, Laurent; Chabernaud, Camille; Bertrand, Philippe; Sembely, Catherine; Sirinelli, Dominique; Castelnau, Pierre; Cottier, Jean-Philippe

    2011-01-01

    Neurofibromatosis type 1 (NF1) is frequently associated with hyperintense lesions on T2-weighted images called ''unidentified bright objects'' (UBO). To better characterize the functional significance of UBO, we investigate the basal ganglia and thalamus using spectroscopic imaging in children with NF1 and compare the results to anomalies observed on T2-weighted images. Magnetic resonance (MR) data of 25 children with NF1 were analyzed. On the basis of T2-weighted images analysis, two groups were identified: one with normal MR imaging (UBO- group; n = 10) and one with UBO (UBO+ group; n = 15). Within the UBO+ group, a subpopulation of patients (n = 5) only had lesions of the basal ganglia. We analyzed herein seven regions of interest (ROIs) for each side: caudate nucleus, capsulo-lenticular region, lateral and posterior thalamus, thalamus (lateral and posterior voxels combined), putamen, and striatum. For each ROI, a spectrum of the metabolites and their ratio was obtained. Patients with abnormalities on T2-weighted images had significantly lower NAA/Cr, NAA/Cho, and NAA/mI ratios in the lateral right thalamus compared with patients with normal T2. These abnormal spectroscopic findings were not observed in capsulo-lenticular regions that had UBO but in the thalamus region that was devoid of UBO. Multivoxel spectroscopic imaging using short-time echo showed spectroscopic abnormalities in the right thalamus of NF1 patients harboring UBO, which were mainly located in the basal ganglia. This finding could reflect the anatomical and functional interactions of these regions. (orig.)

  7. A time-gated near-infrared spectroscopic imaging device for clinical applications.

    Poulet, Patrick; Uhring, Wilfried; Hanselmann, Walter; Glazenborg, René; Nouizi, Farouk; Zint, Virginie; Hirschi, Werner

    2013-03-01

    A time-resolved, spectroscopic, diffuse optical tomography device was assembled for clinical applications like brain functional imaging. The entire instrument lies in a unique setup that includes a light source, an ultrafast time-gated intensified camera and all the electronic control units. The light source is composed of four near infrared laser diodes driven by a nanosecond electrical pulse generator working in a sequential mode at a repetition rate of 100 MHz. The light pulses are less than 80 ps FWHM. They are injected in a four-furcated optical fiber ended with a frontal light distributor to obtain a uniform illumination spot directed towards the head of the patient. Photons back-scattered by the subject are detected by the intensified CCD camera. There are resolved according to their time of flight inside the head. The photocathode is powered by an ultrafast generator producing 50 V pulses, at 100 MHz and a width corresponding to a 200 ps FWHM gate. The intensifier has been specially designed for this application. The whole instrument is controlled by an FPGA based module. All the acquisition parameters are configurable via software through an USB plug and the image data are transferred to a PC via an Ethernet link. The compactness of the device makes it a perfect device for bedside clinical applications. The instrument will be described and characterized. Preliminary data recorded on test samples will be presented.

  8. Immunocytochemistry by electron spectroscopic imaging using well defined boronated monovalent antibody fragments.

    Kessels, M M; Qualmann, B; Sierralta, W D

    1996-01-01

    Contributing to the rapidly developing field of immunoelectron microscopy a new kind of markers has been created. The element boron, incorporated as very stable carborane clusters into different kinds of peptides, served as a marker detectable by electron spectroscopic imaging (ESI)--an electron microscopic technique with high-resolution potential. Covalently linked immunoreagents conspicuous by the small size of both antigen recognizing part and marker moiety are accessible by using peptide concepts for label construction and their conjugation with Fab' fragments. Due to a specific labeling of the free thiol groups of the Fab' fragments, the antigen binding capacity was not affected by the attachment of the markers and the resulting immunoprobes exhibited an elongated shape with the antigen combining site and the label located at opposite ends. The labeling densities observed with these reagents were found to be significantly higher than those obtained by using conventional colloidal gold methods. Combined with digital image processing and analysis systems, boron-based ESI proved to be a powerful approach in ultrastructural immunocytochemistry employing pre- and post-embedding methods.

  9. Changes in NAA and lactate following ischemic stroke: a serial MR spectroscopic imaging study.

    Muñoz Maniega, S; Cvoro, V; Chappell, F M; Armitage, P A; Marshall, I; Bastin, M E; Wardlaw, J M

    2008-12-09

    Although much tissue damage may occur within the first few hours of ischemic stroke, the duration of tissue injury is not well defined. We assessed the temporal pattern of neuronal loss and ischemia after ischemic stroke using magnetic resonance spectroscopic imaging (MRSI) and diffusion-weighted imaging (DWI). We measured N-acetylaspartate (NAA) and lactate in 51 patients with acute ischemic stroke at five time points, from admission to 3 months, in voxels classified as normal, possibly or definitely abnormal (ischemic) according to the appearance of the stroke lesion on the admission DWI. We compared changes in NAA and lactate in different voxel classes using linear mixed models. NAA was significantly reduced from admission in definitely and possibly abnormal (p < 0.01) compared to contralateral normal voxels, reaching a nadir by 2 weeks and remaining reduced at 3 months. Lactate was significantly increased in definitely and possibly abnormal voxels (p < 0.01) during the first 5 days, falling to normal at 2 weeks, rising again later in these voxels. The progressive fall in N-acetylaspartate suggests that some additional neuronal death may continue beyond the first few hours for up to 2 weeks or longer. The mechanism is unclear but, if correct, then it is possible that interventions to limit this ongoing subacute tissue damage might add to the benefit of hyperacute treatment, making further improvements in outcome possible.

  10. Role of endorectal magnetic resonance spectroscopic imaging in two different Gleason scores in prostate cancer.

    Nagarajan, Rajakumar; Margolis, Daniel; McClure, Tim; Raman, Steve; Thomas, M Albert

    2011-01-01

    The major goal of the work was to record three-dimensional magnetic resonance spectroscopic imaging (MRSI) and to compare metabolite ratios between different Gleason scores (GS). MRSI localized by endorectal coil-acquired point-resolved spectroscopy was performed in 14 men with prostate cancer of GS 6 (n = 7) and 7 (n = 7) using a 1.5-tesla MRI scanner. The ratio of (choline + creatine)/citrate was increased with an increase of GS, i.e. 0.590 ± 0.171 in the target lesion and 0.321 ± 0.157 in the contralateral region of patients with a GS of 6 as opposed to 1.082 ± 0.432 in the target lesion and 0.360 ± 0.243 in the contralateral region of patients with a GS of 7. Our pilot results demonstrated that MRSI was an additional biochemical tool which is complementary to the current imaging modalities for early diagnosis and therapeutic management of prostate cancer. Copyright © 2011 S. Karger AG, Basel.

  11. Proton magnetic spectroscopic imaging of the child's brain: the response of tumors to treatment

    Tzika, A.A.; Young Poussaint, T.; Astrakas, L.G.; Barnes, P.D.; Goumnerova, L.; Scott, R.M.; Black, P.McL.; Anthony, D.C.; Billett, A.L.; Tarbell, N.J.

    2001-01-01

    Our aim was to determine and/or predict response to treatment of brain tumors in children using proton magnetic resonance spectroscopic imaging (MRSI). We studied 24 patients aged 10 months to 24 years, using MRI and point-resolved spectroscopy (PRESS; TR 2000 TE 65 ms) with volume preselection and phase-encoding in two dimensions on a 1.5 T imager. Multiple logistic regression was used to establish independent predictors of active tumor growth. Biologically vital cell metabolites, such as N-acetyl aspartate and choline-containing compounds (Cho), were significantly different between tumor and control tissues (P<0.001). The eight brain tumors which responded to radiation or chemotherapy, exhibited lower Cho (P=0.05), higher total creatine (tCr) (P=0.02) and lower lactate and lipid (L) (P=0.04) than16 tumors which were not treated (except by surgery) or did not respond to treatment. The only significant independent predictor of active tumor growth was tCr (P<0.01). We suggest that tCr is useful in assessing response of brain tumors to treatment. (orig.)

  12. Automated prescription of oblique brain 3D magnetic resonance spectroscopic imaging.

    Ozhinsky, Eugene; Vigneron, Daniel B; Chang, Susan M; Nelson, Sarah J

    2013-04-01

    Two major difficulties encountered in implementing Magnetic Resonance Spectroscopic Imaging (MRSI) in a clinical setting are limited coverage and difficulty in prescription. The goal of this project was to automate completely the process of 3D PRESS MRSI prescription, including placement of the selection box, saturation bands and shim volume, while maximizing the coverage of the brain. The automated prescription technique included acquisition of an anatomical MRI image, optimization of the oblique selection box parameters, optimization of the placement of outer-volume suppression saturation bands, and loading of the calculated parameters into a customized 3D MRSI pulse sequence. To validate the technique and compare its performance with existing protocols, 3D MRSI data were acquired from six exams from three healthy volunteers. To assess the performance of the automated 3D MRSI prescription for patients with brain tumors, the data were collected from 16 exams from 8 subjects with gliomas. This technique demonstrated robust coverage of the tumor, high consistency of prescription and very good data quality within the T2 lesion. Copyright © 2012 Wiley Periodicals, Inc.

  13. Global Solar Radiation in Spain from Satellite Images

    Ramirez, L.; Mora, L.; Sidrach de Cardona, M.; Navarro, A. A.; Varela, M.; Cruz, M. de la

    2003-01-01

    In the context of the present work a series of algorithms of calculation of the solar radiation from satellite images has been developed. These models, have been applied to three years of images of the Meteosat satellite and the results of the treatment have been extrapolated to long term. For the development of the models of solar radiation registered in ground stations have been used, corresponding all of them to localities of peninsular Spain and the Balearic ones. The maximum periods of data available have been used, supposing in most of the cases periods of between 6 and 9 years. From the results has a year type of images of global solar radiation on horizontal surface. The original resolution of the image of 7x7 km in the study latitudes, has been reevaluated to 5x5 km. This supposes to have a value of the typical radiation for every day of the year, each 5x5 km in the study territory. This information, supposes an important advance as far as the knowledge of the space distribution of the radiation solar, impossible to reach about alternative methods. Doubtlessly, the precision of the provided values is not comparable with pyrano metric measures in a concrete locality, but it provides a very valid indicator in places in which it is not had previous information. In addition to the radiation maps, tables of the global solar radiation have been prepared on different inclinations, from the global radiation on horizontal surface calculated for every day of the year and in each pixel of the image. (Author) 24 refs

  14. Notable Images of the 2017 Total Solar Eclipse

    Wilson, Teresa; Dahiwale, Aishwarya; Nemiroff, Robert; Bonnell, Jerry

    2018-01-01

    The "Great American Eclipse" – the total solar eclipse visible across the USA on 21 August 2017 – resulted in some notable eclipse images and videos high in educational and scientific value. Some of the images that were selected to appear on the Astronomy Picture of the Day (APOD) website are shown in high resolution accompanied by educational descriptions. The questions of whether this eclipse was the most viewed and the most photographed event of any type in human history will be discussed. People are invited to come by and share their own eclipse images and stories.

  15. Spectroscopic Evidence of Alfvén Wave Damping in the Off-limb Solar Corona

    Gupta, G. R., E-mail: girjesh@iucaa.in [Inter-University Centre for Astronomy and Astrophysics, Post Bag-4, Ganeshkhind, Pune 411007 (India)

    2017-02-10

    We investigate the off-limb active-region and quiet-Sun corona using spectroscopic data. The active region is clearly visible in several spectral lines formed in the temperature range of 1.1–2.8 MK. We derive the electron number density using the line ratio method, and the nonthermal velocity in the off-limb region up to the distance of 140 Mm. We compare density scale heights derived from several spectral line pairs with expected scale heights per the hydrostatic equilibrium model. Using several isolated and unblended spectral line profiles, we estimate nonthermal velocities in the active region and quiet Sun. Nonthermal velocities obtained from warm lines in the active region first show an increase and then later either a decrease or remain almost constant with height in the far off-limb region, whereas nonthermal velocities obtained from hot lines show consistent decrease. However, in the quiet-Sun region, nonthermal velocities obtained from various spectral lines show either a gradual decrease or remain almost constant with height. Using these obtained parameters, we further calculate Alfvén wave energy flux in both active and quiet-Sun regions. We find a significant decrease in wave energy fluxes with height, and hence provide evidence of Alfvén wave damping. Furthermore, we derive damping lengths of Alfvén waves in the both regions and find them to be in the range of 25–170 Mm. Different damping lengths obtained at different temperatures may be explained as either possible temperature-dependent damping or by measurements obtained in different coronal structures formed at different temperatures along the line of sight. Temperature-dependent damping may suggest some role of thermal conduction in the damping of Alfvén waves in the lower corona.

  16. Diffusion tensor spectroscopic imaging of the human brain in children and adults.

    Fotso, Kevin; Dager, Stephen R; Landow, Alec; Ackley, Elena; Myers, Orrin; Dixon, Mindy; Shaw, Dennis; Corrigan, Neva M; Posse, Stefan

    2017-10-01

    We developed diffusion tensor spectroscopic imaging (DTSI), based on proton-echo-planar-spectroscopic imaging (PEPSI), and evaluated the feasibility of mapping brain metabolite diffusion in adults and children. PRESS prelocalized DTSI at 3 Tesla (T) was performed using navigator-based correction of movement-related phase errors and cardiac gating with compensation for repetition time (TR) related variability in T 1 saturation. Mean diffusivity (MD) and fractional anisotropy (FA) of total N-acetyl-aspartate (tNAA), total creatine (tCr), and total choline (tCho) were measured in eight adults (17-60 years) and 10 children (3-24 months) using b max  = 1734 s/mm 2 , 1 cc and 4.5 cc voxel sizes, with nominal scan times of 17 min and 8:24 min. Residual movement-related phase encoding ghosting (PEG) was used as a regressor across scans to correct overestimation of MD. After correction for PEG, metabolite slice-averaged MD estimated at 20% PEG were lower (P < 0.042) for adults (0.17/0.20/0.18 × 10 -3 mm 2 /s) than for children (0.26/0.27/0.24 × 10 -3 mm 2 /s). Extrapolated to 0% PEG, the MD estimates decreased further (0.09/0.11/0.11 × 10 -3 mm 2 /s versus 0.15/0.16/0.15 × 10 -3 mm 2 /s). Slice-averaged FA of tNAA (P = 0.049), tCr (P = 0.067), and tCho (P = 0.003) were higher in children. This high-speed DTSI approach with PEG regression allows for estimation of metabolite MD and FA with improved tolerance to movement. Our preliminary data suggesting age-related changes support DTSI as a sensitive technique for investigating intracellular markers of biological processes. Magn Reson Med 78:1246-1256, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  17. ON THE COMBINATION OF IMAGING-POLARIMETRY WITH SPECTROPOLARIMETRY OF UPPER SOLAR ATMOSPHERES DURING SOLAR ECLIPSES

    Qu, Z. Q.; Deng, L. H.; Dun, G. T.; Chang, L.; Zhang, X. Y.; Cheng, X. M.; Qu, Z. N.; Xue, Z. K.; Ma, L.; Allington-Smith, J.; Murray, G.

    2013-01-01

    We present results from imaging polarimetry (IP) of upper solar atmospheres during a total solar eclipse on 2012 November 13 and spectropolarimetry of an annular solar eclipse on 2010 January 15. This combination of techniques provides both the synoptic spatial distribution of polarization above the solar limb and spectral information on the physical mechanism producing the polarization. Using these techniques together we demonstrate that even in the transition region, the linear polarization increases with height and can exceed 20%. IP shows a relatively smooth background distribution in terms of the amplitude and direction modified by solar structures above the limb. A map of a new quantity that reflects direction departure from the background polarization supplies an effective technique to improve the contrast of this fine structure. Spectral polarimetry shows that the relative contribution to the integrated polarization over the observed passband from the spectral lines decreases with height while the contribution from the continuum increases as a general trend. We conclude that both imaging and spectral polarimetry obtained simultaneously over matched spatial and spectral domains will be fruitful for future eclipse observations

  18. Imaging a Magnetic-breakout Solar Eruption

    Chen, Yao; Du, Guohui; Zhao, Di; Wu, Zhao; Liu, Wei; Wang, Bing; Ruan, Guiping; Feng, Shiwei; Song, Hongqiang

    2016-04-01

    The fundamental mechanism initiating coronal mass ejections (CMEs) remains controversial. One of the leading theories is magnetic breakout, in which magnetic reconnection occurring high in the corona removes the confinement on an energized low-corona structure from the overlying magnetic field, thus allowing it to erupt. Here, we report critical observational evidence of this elusive breakout reconnection in a multi-polar magnetic configuration that leads to a CME and an X-class, long-duration flare. Its occurrence is supported by the presence of pairs of heated cusp-shaped loops around an X-type null point and signatures of reconnection inflows. Other peculiar features new to the breakout picture include sequential loop brightening, coronal hard X-rays at energies up to ˜100 keV, and extended high-corona X-rays above the later restored multi-polar structure. These observations, from a novel perspective with clarity never achieved before, present crucial clues to understanding the initiation mechanism of solar eruptions.

  19. IMAGING A MAGNETIC-BREAKOUT SOLAR ERUPTION

    Chen, Yao; Du, Guohui; Zhao, Di; Wu, Zhao; Wang, Bing; Ruan, Guiping; Feng, Shiwei; Song, Hongqiang; Liu, Wei

    2016-01-01

    The fundamental mechanism initiating coronal mass ejections (CMEs) remains controversial. One of the leading theories is magnetic breakout, in which magnetic reconnection occurring high in the corona removes the confinement on an energized low-corona structure from the overlying magnetic field, thus allowing it to erupt. Here, we report critical observational evidence of this elusive breakout reconnection in a multi-polar magnetic configuration that leads to a CME and an X-class, long-duration flare. Its occurrence is supported by the presence of pairs of heated cusp-shaped loops around an X-type null point and signatures of reconnection inflows. Other peculiar features new to the breakout picture include sequential loop brightening, coronal hard X-rays at energies up to ∼100 keV, and extended high-corona X-rays above the later restored multi-polar structure. These observations, from a novel perspective with clarity never achieved before, present crucial clues to understanding the initiation mechanism of solar eruptions

  20. The biocompatibility of carbon hydroxyapatite/β-glucan composite for bone tissue engineering studied with Raman and FTIR spectroscopic imaging.

    Sroka-Bartnicka, Anna; Kimber, James A; Borkowski, Leszek; Pawlowska, Marta; Polkowska, Izabela; Kalisz, Grzegorz; Belcarz, Anna; Jozwiak, Krzysztof; Ginalska, Grazyna; Kazarian, Sergei G

    2015-10-01

    The spectroscopic approaches of FTIR imaging and Raman mapping were applied to the characterisation of a new carbon hydroxyapatite/β-glucan composite developed for bone tissue engineering. The composite is an artificial bone material with an apatite-forming ability for the bone repair process. Rabbit bone samples were tested with an implanted bioactive material for a period of several months. Using spectroscopic and chemometric methods, we were able to determine the presence of amides and phosphates and the distribution of lipid-rich domains in the bone tissue, providing an assessment of the composite's bioactivity. Samples were also imaged in transmission using an infrared microscope combined with a focal plane array detector. CaF2 lenses were also used on the infrared microscope to improve spectral quality by reducing scattering artefacts, improving chemometric analysis. The presence of collagen and lipids at the bone/composite interface confirmed biocompatibility and demonstrate the suitability of FTIR microscopic imaging with lenses in studying these samples. It confirmed that the composite is a very good background for collagen growth and increases collagen maturity with the time of the bone growth process. The results indicate the bioactive and biocompatible properties of this composite and demonstrate how Raman and FTIR spectroscopic imaging have been used as an effective tool for tissue characterisation.

  1. A visibility-based approach using regularization for imaging-spectroscopy in solar X-ray astronomy

    Prato, M; Massone, A M; Piana, M [CNR - INFM LAMIA, Via Dodecaneso 33 1-16146 Genova (Italy); Emslie, A G [Department of Physics, Oklahoma State University, Stillwater, OK 74078 (United States); Hurford, G J [Space Sciences Laboratory, University of California at Berkeley, 8 Gauss Way, Berkeley, CA 94720-7450 (United States); Kontar, E P [Department of Physics and Astronomy, The University, Glasgow G12 8QQ, Scotland (United Kingdom); Schwartz, R A [CUA - Catholic University and LSSP at NASA Goddard Space Flight Center, code 671.1 Greenbelt, MD 20771 (United States)], E-mail: massone@ge.infm.it

    2008-11-01

    The Reuven Ramaty High-Energy Solar Spectroscopic Imager (RHESSI) is a nine-collimators satellite detecting X-rays and {gamma}-rays emitted by the Sun during flares. As the spacecraft rotates, imaging information is encoded as rapid time-variations of the detected flux. We recently proposed a method for the construction of electron flux maps at different electron energies from sets of count visibilities (i.e., direct, calibrated measurements of specific Fourier components of the source spatial structure) measured by RHESSI. The method requires the application of regularized inversion for the synthesis of electron visibility spectra and of imaging techniques for the reconstruction of two-dimensional electron flux maps. The method, already tested on real events registered by RHESSI, is validated in this paper by means of simulated realistic data.

  2. Fourier transform infrared spectroscopic imaging and multivariate regression for prediction of proteoglycan content of articular cartilage.

    Lassi Rieppo

    Full Text Available Fourier Transform Infrared (FT-IR spectroscopic imaging has been earlier applied for the spatial estimation of the collagen and the proteoglycan (PG contents of articular cartilage (AC. However, earlier studies have been limited to the use of univariate analysis techniques. Current analysis methods lack the needed specificity for collagen and PGs. The aim of the present study was to evaluate the suitability of partial least squares regression (PLSR and principal component regression (PCR methods for the analysis of the PG content of AC. Multivariate regression models were compared with earlier used univariate methods and tested with a sample material consisting of healthy and enzymatically degraded steer AC. Chondroitinase ABC enzyme was used to increase the variation in PG content levels as compared to intact AC. Digital densitometric measurements of Safranin O-stained sections provided the reference for PG content. The results showed that multivariate regression models predict PG content of AC significantly better than earlier used absorbance spectrum (i.e. the area of carbohydrate region with or without amide I normalization or second derivative spectrum univariate parameters. Increased molecular specificity favours the use of multivariate regression models, but they require more knowledge of chemometric analysis and extended laboratory resources for gathering reference data for establishing the models. When true molecular specificity is required, the multivariate models should be used.

  3. 1H-MR-spectroscopic imaging in patients with Alzheimer's disease

    Block, W.; Traeber, F.; Kuhl, C.K.; Fric, M.; Keller, E.; Lamerichs, R.; Rink, H.; Moeller, H.J.; Schild, H.H.

    1995-01-01

    To detect regional differences in accompanying metabolic changes, 1 H-Magnetic Resonance Spectroscopic Imaging was performed in 16 patients with Alzheimer's disease (AD); the clinical diagnosis was based upon DSM-III-R and NINCDS-ADRDA guidelines. In the hippocampal region metabolic maps of the local distribution of N-acetylaspartate (NAA), choline (Cho), creatine compounds (P(Cr)) and lactate were determined. Ratios of Cho/NAA, (P)Cr/NAA and Cho/(P)Cr calculated from selected hippocampal spectra were compared to those from healthy volunteers (n=17). AD patients demonstrated an increase of Cho/NAA and (P)Cr/NAA ratios caused by increased choline compounds and decreased NAA. These alterations were observed in 11/12 cases in the hippocampal and in 7/12 in the temporo-occipital region. Hippocampal Cho/NAA ratios (0.56±0.19) were significantly elevated compared with controls. The observed elevation of choline compounds in the hippocampus supports the hypothesis that alterations in the cholinergic system play an important role in Alzheimer's disease. The observed reduction of NAA is due to neuronal degeneration. (orig./MG) [de

  4. Practical protocols for fast histopathology by Fourier transform infrared spectroscopic imaging

    Keith, Frances N.; Reddy, Rohith K.; Bhargava, Rohit

    2008-02-01

    Fourier transform infrared (FT-IR) spectroscopic imaging is an emerging technique that combines the molecular selectivity of spectroscopy with the spatial specificity of optical microscopy. We demonstrate a new concept in obtaining high fidelity data using commercial array detectors coupled to a microscope and Michelson interferometer. Next, we apply the developed technique to rapidly provide automated histopathologic information for breast cancer. Traditionally, disease diagnoses are based on optical examinations of stained tissue and involve a skilled recognition of morphological patterns of specific cell types (histopathology). Consequently, histopathologic determinations are a time consuming, subjective process with innate intra- and inter-operator variability. Utilizing endogenous molecular contrast inherent in vibrational spectra, specially designed tissue microarrays and pattern recognition of specific biochemical features, we report an integrated algorithm for automated classifications. The developed protocol is objective, statistically significant and, being compatible with current tissue processing procedures, holds potential for routine clinical diagnoses. We first demonstrate that the classification of tissue type (histology) can be accomplished in a manner that is robust and rigorous. Since data quality and classifier performance are linked, we quantify the relationship through our analysis model. Last, we demonstrate the application of the minimum noise fraction (MNF) transform to improve tissue segmentation.

  5. Impedance Spectroscopic Investigation of the Degraded Dye-Sensitized Solar Cell due to Ageing

    Parth Bhatt

    2016-01-01

    Full Text Available This paper investigates the effect of ageing on the performance of dye-sensitized solar cells (DSCs. The electrical characterization of fresh and degraded DSCs is done under AM1.5G spectrum and the current density-voltage (J-V characteristics are analyzed. Short circuit current density (JSC decreases significantly whereas a noticeable increase in open circuit voltage is observed. These results have been further investigated electroanalytically using electrochemical impedance spectroscopy (EIS. An increase in net resistance results in a lower JSC for the degraded DSC. This decrease in current is mainly due to degradation of TiO2-dye interface, which is observed from light and dark J-V characteristics and is further confirmed by EIS measurements. A reduction in the chemical capacitance of the degraded DSC is observed, which is responsible for the shifting of Fermi level with respect to conduction band edge that further results in an increase of open circuit voltage for the degraded DSC. It is also confirmed from EIS that the degradation leads to a better contact formation between the electrolyte and Pt electrode, which improves the fill factor of the DSC. But the recombination throughout the DSC is found to increase along with degradation. This study suggests that the DSC should be used under low illumination conditions and around room temperature for a longer life.

  6. Phosphorus magnetic resonance spectroscopic imaging at 7 T in patients with prostate cancer.

    Lagemaat, Miriam W; Vos, Eline K; Maas, Marnix C; Bitz, Andreas K; Orzada, Stephan; van Uden, Mark J; Kobus, Thiele; Heerschap, Arend; Scheenen, Tom W J

    2014-05-01

    The aim of this study was to identify characteristics of phosphorus (P) spectra of the human prostate and to investigate changes of individual phospholipid metabolites in prostate cancer through in vivo P magnetic resonance spectroscopic imaging (MRSI) at 7 T. In this institutional review board-approved study, 15 patients with biopsy-proven prostate cancer underwent T2-weighted magnetic resonance imaging and 3-dimensional P MRSI at 7 T. Voxels were selected at the tumor location, in normal-appearing peripheral zone tissue, normal-appearing transition zone tissue, and in the base of the prostate close to the seminal vesicles. Phosphorus metabolite ratios were determined and compared between tissue types. Signals of phosphoethanolamine (PE) and phosphocholine (PC) were present and well resolved in most P spectra in the prostate. Glycerophosphocholine signals were observable in 43% of the voxels in malignant tissue, but in only 10% of the voxels in normal-appearing tissue away from the seminal vesicles. In many spectra, independent of tissue type, 2 peaks resonated in the chemical shift range of inorganic phosphate, possibly representing 2 separate pH compartments. The PC/PE ratio in the seminal vesicles was highly elevated compared with the prostate in 5 patients. A considerable overlap of P metabolite ratios was found between prostate cancer and normal-appearing prostate tissue, preventing direct discrimination of these tissues. The only 2 patients with high Gleason scores tumors (≥4+5) presented with high PC and glycerophosphocholine levels in their cancer lesions. Phosphorus MRSI at 7 T shows distinct features of phospholipid metabolites in the prostate gland and its surrounding structures. In this exploratory study, no differences in P metabolite ratios were observed between prostate cancer and normal-appearing prostate tissue possibly because of the partial volume effects of small tumor foci in large MRSI voxels.

  7. The role of gray and white matter segmentation in quantitative proton MR spectroscopic imaging.

    Tal, Assaf; Kirov, Ivan I; Grossman, Robert I; Gonen, Oded

    2012-12-01

    Since the brain's gray matter (GM) and white matter (WM) metabolite concentrations differ, their partial volumes can vary the voxel's ¹H MR spectroscopy (¹H-MRS) signal, reducing sensitivity to changes. While single-voxel ¹H-MRS cannot differentiate between WM and GM signals, partial volume correction is feasible by MR spectroscopic imaging (MRSI) using segmentation of the MRI acquired for VOI placement. To determine the magnitude of this effect on metabolic quantification, we segmented a 1-mm³ resolution MRI into GM, WM and CSF masks that were co-registered with the MRSI grid to yield their partial volumes in approximately every 1 cm³ spectroscopic voxel. Each voxel then provided one equation with two unknowns: its i- metabolite's GM and WM concentrations C(i) (GM) , C(i) (WM) . With the voxels' GM and WM volumes as independent coefficients, the over-determined system of equations was solved for the global averaged C(i) (GM) and C(i) (WM) . Trading off local concentration differences offers three advantages: (i) higher sensitivity due to combined data from many voxels; (ii) improved specificity to WM versus GM changes; and (iii) reduced susceptibility to partial volume effects. These improvements made no additional demands on the protocol, measurement time or hardware. Applying this approach to 18 volunteered 3D MRSI sets of 480 voxels each yielded N-acetylaspartate, creatine, choline and myo-inositol C(i) (GM) concentrations of 8.5 ± 0.7, 6.9 ± 0.6, 1.2 ± 0.2, 5.3 ± 0.6 mM, respectively, and C(i) (WM) concentrations of 7.7 ± 0.6, 4.9 ± 0.5, 1.4 ± 0.1 and 4.4 ± 0.6mM, respectively. We showed that unaccounted voxel WM or GM partial volume can vary absolute quantification by 5-10% (more for ratios), which can often double the sample size required to establish statistical significance. Copyright © 2012 John Wiley & Sons, Ltd.

  8. Thumb-size ultrasonic-assisted spectroscopic imager for in-situ glucose monitoring as optional sensor of conventional dialyzers

    Nogo, Kosuke; Mori, Keita; Qi, Wei; Hosono, Satsuki; Kawashima, Natsumi; Nishiyama, Akira; Wada, Kenji; Ishimaru, Ichiro

    2016-03-01

    We proposed the ultrasonic-assisted spectroscopic imaging for the realization of blood-glucose-level monitoring during dialytic therapy. Optical scattering and absorption caused by blood cells deteriorate the detection accuracy of glucose dissolved in plasma. Ultrasonic standing waves can agglomerate blood cells at nodes. In contrast, around anti-node regions, the amount of transmitted light increases because relatively clear plasma appears due to decline the number of blood cells. Proposed method can disperse the transmitted light of plasma without time-consuming pretreatment such as centrifugation. To realize the thumb-size glucose sensor which can be easily attached to dialysis tubes, an ultrasonic standing wave generator and a spectroscopic imager are required to be small. Ultrasonic oscillators are ∅30[mm]. A drive circuit of oscillators, which now size is 41×55×45[mm], is expected to become small. The trial apparatus of proposed one-shot Fourier spectroscopic imager, whose size is 30×30×48[mm], also can be little-finger size in principal. In the experiment, we separated the suspension mixed water and micro spheres (Θ10[mm) into particles and liquid regions with the ultrasonic standing wave (frequency: 2[MHz]). Furthermore, the spectrum of transmitted light through the suspension could be obtained in visible light regions with a white LED.

  9. Endorectal coil MRI and MR-spectroscopic imaging in patients with elevated serum prostate specific antigen with negative trus transrectal ultrasound guided biopsy

    Farooq Ahmad Ganie

    2013-01-01

    Conclusion: Prostatic biopsy directed with endorectal coil MRI and MR-spectroscopic imaging findings in patients with elevated serum PSA and prior negative biopsy, improves the early diagnosis of prostatic carcinoma and accurate localization of prostate cancer within the gland.

  10. AN IMAGING STUDY OF A COMPLEX SOLAR CORONAL RADIO ERUPTION

    Feng, S. W.; Chen, Y.; Song, H. Q.; Wang, B.; Kong, X. L., E-mail: yaochen@sdu.edu.cn [Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment, and Institute of Space Sciences, Shandong University, Weihai, Shandong 264209 (China)

    2016-08-10

    Solar coronal radio bursts are enhanced radio emission excited by energetic electrons accelerated during solar eruptions. Studying these bursts is important for investigating the origin and physical mechanism of energetic particles and further diagnosing coronal parameters. Earlier studies suffered from a lack of simultaneous high-quality imaging data of the radio burst and the eruptive structure in the inner corona. Here we present a study on a complex solar radio eruption consisting of a type II burst and three reversely drifting type III bursts, using simultaneous EUV and radio imaging data. It is found that the type II burst is closely associated with a propagating and evolving CME-driven EUV shock structure, originated initially at the northern shock flank and later transferred to the top part of the shock. This source transfer is coincident with the presence of shock decay and enhancing signatures observed at the corresponding side of the EUV front. The electron energy accelerated by the shock at the flank is estimated to be ∼0.3 c by examining the imaging data of the fast-drifting herringbone structure of the type II burst. The reverse-drifting type III sources are found to be within the ejecta and correlated with a likely reconnection event therein. The implications for further observational studies and relevant space weather forecasting techniques are discussed.

  11. Initial results from the fast imaging solar spectrograph (FISS)

    2015-01-01

    This collection of papers describes the instrument and initial results obtained from the Fast Imaging Solar Spectrograph (FISS),  one of the post-focus instruments of the 1.6 meter New Solar Telescope at the Big Bear Solar Observatory. The FISS primarily aims at investigating structures and dynamics of  chromospheric features. This instrument is a dual-band Echelle spectrograph optimized for the simultaneous recording of the H I 656.3 nm band and the Ca II 854.2 nm band. The imaging is done with the fast raster scan realized by the linear motion of a two-mirror scanner, and its quality is determined by the performance of the adaptive optics of the telescope.    These papers illustrate the capability of the early FISS observations in the study of chromospheric features. Since the imaging quality has been improved a lot with the advance of the adaptive optics, one can obtain much better data with the current FISS observations.        This volume is aimed at graduate students and researchers working in...

  12. A spectroscopic survey of the youngest field stars in the solar neighborhood . II. The optically faint sample

    Frasca, A.; Guillout, P.; Klutsch, A.; Ferrero, R. Freire; Marilli, E.; Biazzo, K.; Gandolfi, D.; Montes, D.

    2018-05-01

    Context. Star formation in the solar neighborhood is mainly traced by young stars in open clusters, associations, and in the field, which can be identified, for example, by their X-ray emission. The determination of stellar parameters for the optical counterparts of X-ray sources is crucial for a full characterization of these stars. Aims: This work extends the spectroscopic study of the RasTyc sample, obtained by the cross-correlation of the Tycho and ROSAT All-Sky Survey catalogs, to stars fainter than V = 9.5 mag and aims to identify sparse populations of young stars in the solar neighborhood. Methods: We acquired 625 high-resolution spectra for 443 presumably young stars with four different instruments in the northern hemisphere. The radial and rotational velocity (vsini) of our targets were measured by means of the cross-correlation technique, which is also helpful to discover single-lined (SB1), double-lined spectroscopic binaries (SB2), and multiple systems. We used the code ROTFIT to perform an MK spectral classification and to determine the atmospheric parameters (Teff, logg, [Fe/H]) and vsini of the single stars and SB1 systems. For these objects, we used the spectral subtraction of slowly rotating templates to measure the equivalent widths of the Hα and Li I 6708 Å lines, which enabled us to derive their chromospheric activity level and lithium abundance. We made use of Gaia DR1 parallaxes and proper motions to locate the targets in the Hertzsprung-Russell (HR) diagram and to compute the space velocity components of the youngest objects. Results: We find a remarkable percentage (at least 35%) of binaries and multiple systems. On the basis of the lithium abundance, the sample of single stars and SB1 systems appears to be mostly ( 60%) composed of stars younger than the members of the UMa cluster. The remaining sources are in the age range between the UMa and Hyades clusters ( 20%) or older ( 20%). In total, we identify 42 very young (PMS-like) stars

  13. Spectroscopic elucidation of energy transfer in hybrid inorganic-biological organisms for solar-to-chemical production.

    Kornienko, Nikolay; Sakimoto, Kelsey K; Herlihy, David M; Nguyen, Son C; Alivisatos, A Paul; Harris, Charles B; Schwartzberg, Adam; Yang, Peidong

    2016-10-18

    The rise of inorganic-biological hybrid organisms for solar-to-chemical production has spurred mechanistic investigations into the dynamics of the biotic-abiotic interface to drive the development of next-generation systems. The model system, Moorella thermoacetica-cadmium sulfide (CdS), combines an inorganic semiconductor nanoparticle light harvester with an acetogenic bacterium to drive the photosynthetic reduction of CO 2 to acetic acid with high efficiency. In this work, we report insights into this unique electrotrophic behavior and propose a charge-transfer mechanism from CdS to M. thermoacetica Transient absorption (TA) spectroscopy revealed that photoexcited electron transfer rates increase with increasing hydrogenase (H 2 ase) enzyme activity. On the same time scale as the TA spectroscopy, time-resolved infrared (TRIR) spectroscopy showed spectral changes in the 1,700-1,900-cm -1 spectral region. The quantum efficiency of this system for photosynthetic acetic acid generation also increased with increasing H 2 ase activity and shorter carrier lifetimes when averaged over the first 24 h of photosynthesis. However, within the initial 3 h of photosynthesis, the rate followed an opposite trend: The bacteria with the lowest H 2 ase activity photosynthesized acetic acid the fastest. These results suggest a two-pathway mechanism: a high quantum efficiency charge-transfer pathway to H 2 ase generating H 2 as a molecular intermediate that dominates at long time scales (24 h), and a direct energy-transducing enzymatic pathway responsible for acetic acid production at short time scales (3 h). This work represents a promising platform to utilize conventional spectroscopic methodology to extract insights from more complex biotic-abiotic hybrid systems.

  14. Full-disk Solar H-alpha Images From GONG

    Harvey, J. W.; Bolding, J.; Clark, R.; Hauth, D.; Hill, F.; Kroll, R.; Luis, G.; Mills, N.; Purdy, T.; Henney, C.; Holland, D.; Winter, J.

    2011-05-01

    Since mid-2010 the Global Oscillation Network Group (GONG) has collected H-alpha images at six sites around the world. These images provide a near real-time solar activity patrol for use in space weather applications and also an archive for research purposes. Images are collected once per minute, dark, smear, and flat corrected, compressed and then sent via the Internet to a 'cloud' server where reduction is completed. Various reduced images are usually available within a minute after exposure. The H-alpha system is an add-on to the normal GONG helioseismology instrument and does not interfere with regular observations. A polarizing beamsplitter sends otherwise unused 656 nm light through two lenses to a Daystar 0.04 nm mica etalon filter. The filter is matched to an image of the GONG light feed entrance pupil and sees an image of the Sun at infinity. Two lenses behind the filter form the solar image on a DVC-4000 2k x 2k interline transfer CCD camera. Exposure times are automatically adjusted to maintain the quiet disk center at 20% of full dynamic range to avoid saturation by bright flares. Image resolution is limited by diffraction, seeing and some high-order wavefront errors in the filters. A unique dual-heater system was developed by Daystar to homogenize the passband characteristics of the mica etalons. The data are in regular use for space weather forecasting by the U.S. Air Force Weather Agency, which funded construction and installation of the instruments. Operational and reduction improvements are underway and archived data are already being used for research projects. The Web site URL is http://halpha.nso.edu.

  15. Corrosion investigation of fire-gilded bronze involving high surface resolution spectroscopic imaging

    Masi, G.; Chiavari, C.; Avila, J.; Esvan, J.; Raffo, S.; Bignozzi, M.C.; Asensio, M.C.; Robbiola, L.

    2016-01-01

    Graphical abstract: - Highlights: • Fire-gilded bronze prepared by ancient methods (Au–Hg layer on Cu–Sn–Zn–Pb–Sb). • Heating during gilding induces Sn and Znenrichment in the top part of the gilded layer. • SR-HRPES mapping of corrosion craters (cross-section) after accelerated ageing. • Selective dissolution of Cu and Zn in the craters induces Sn species enrichment. • The main species in the craters are related to hydroxi-oxide compounds. - Abstract: Gilded bronzes are often affected by severe corrosion, due to defects in the Au layer and Au/Cu alloy galvanic coupling, stimulated by large cathodic area of the gilded layer. Galvanic corrosion, triggered by gilding defects, leads to products growth at the Au/bronze interface, inducing blistering or break-up of the Au layer. In this context, fire-gilded bronze replicas prepared by ancient methods (use of spreadable Au–Hg paste) was specifically characterised by compiling complementary spectroscopic and imaging information before/after accelerated ageing with synthetic rain. Fire-gilded bronze samples were chemically imaged in cross-section at nano-metric scale (<200 nm) using high energy and lateral resolution synchrotron radiation photoemission (HR-SRPES) of core levels and valence band after conventional characterisation of the samples by Glow Discharge optical Emission Spectroscopy (GD-OES) and conventional X-ray photoelectron spectroscopy (XPS). We have found a net surface enrichment in Zn and Sn after fire-gilding and presence of metallic Hg, Pb and Cu within the Au layer. Moreover, the composition distribution of the elements together with their oxidation has been determined. It was also revealed that metallic phases including Hg and Pb remain in the gilding after corrosion. Moreover, selective dissolution of Zn and Cu occurs in the crater due to galvanic coupling, which locally induces relative Sn species enrichment (decuprification). The feasibility advantages and disadvantages of

  16. Corrosion investigation of fire-gilded bronze involving high surface resolution spectroscopic imaging

    Masi, G., E-mail: giulia.masi5@unibo.it [Dipartimento di Ingegneria Civile, Chimica, Ambientale e dei Materiali, Università di Bologna, via Terracini 28, 40131 Bologna (Italy); Chiavari, C., E-mail: cristina.chiavari@unibo.it [Dipartimento di Ingegneria Civile, Chimica, Ambientale e dei Materiali, Università di Bologna, via Terracini 28, 40131 Bologna (Italy); C.I.R.I. (Centro Interdipartimentale Ricerca Industriale) Meccanica Avanzata e Materiali, Università di Bologna, Bologna, via Terracini 28, 40131 Bologna (Italy); Avila, J., E-mail: jose.avila@synchrotron-soleil.fr [Synchrotron SOLEIL, L’Orme des Merisiers, 91190 Saint-Aubin (France); Esvan, J., E-mail: jerome.esvan@ensiacet.fr [Centre Interuniversitaire de Recherche et d’Ingénierie des Matériaux, Université de Toulouse, 4 allée Emile Monso, 31030 Toulouse (France); Raffo, S., E-mail: simona.raffo2@unibo.it [Dipartimento di Chimica Industriale “Toso Montanari”, Università di Bologna, viale Risorgimento 4, 40136 Bologna (Italy); Bignozzi, M.C., E-mail: maria.bignozzi@unibo.it [Dipartimento di Ingegneria Civile, Chimica, Ambientale e dei Materiali, Università di Bologna, via Terracini 28, 40131 Bologna (Italy); Asensio, M.C., E-mail: maria-carmen.asensio@synchrotron-soleil.fr [Synchrotron SOLEIL, L’Orme des Merisiers, 91190 Saint-Aubin (France); Robbiola, L., E-mail: robbiola@univ-tlse2.fr [TRACES Lab (CNRS UMR5608), Université Toulouse Jean-Jaurès, 5, allées Antonio-Machado, 31058 Toulouse (France); and others

    2016-03-15

    Graphical abstract: - Highlights: • Fire-gilded bronze prepared by ancient methods (Au–Hg layer on Cu–Sn–Zn–Pb–Sb). • Heating during gilding induces Sn and Znenrichment in the top part of the gilded layer. • SR-HRPES mapping of corrosion craters (cross-section) after accelerated ageing. • Selective dissolution of Cu and Zn in the craters induces Sn species enrichment. • The main species in the craters are related to hydroxi-oxide compounds. - Abstract: Gilded bronzes are often affected by severe corrosion, due to defects in the Au layer and Au/Cu alloy galvanic coupling, stimulated by large cathodic area of the gilded layer. Galvanic corrosion, triggered by gilding defects, leads to products growth at the Au/bronze interface, inducing blistering or break-up of the Au layer. In this context, fire-gilded bronze replicas prepared by ancient methods (use of spreadable Au–Hg paste) was specifically characterised by compiling complementary spectroscopic and imaging information before/after accelerated ageing with synthetic rain. Fire-gilded bronze samples were chemically imaged in cross-section at nano-metric scale (<200 nm) using high energy and lateral resolution synchrotron radiation photoemission (HR-SRPES) of core levels and valence band after conventional characterisation of the samples by Glow Discharge optical Emission Spectroscopy (GD-OES) and conventional X-ray photoelectron spectroscopy (XPS). We have found a net surface enrichment in Zn and Sn after fire-gilding and presence of metallic Hg, Pb and Cu within the Au layer. Moreover, the composition distribution of the elements together with their oxidation has been determined. It was also revealed that metallic phases including Hg and Pb remain in the gilding after corrosion. Moreover, selective dissolution of Zn and Cu occurs in the crater due to galvanic coupling, which locally induces relative Sn species enrichment (decuprification). The feasibility advantages and disadvantages of

  17. Apertureless near-field/far-field CW two-photon microscope for biological and material imaging and spectroscopic applications.

    Nowak, Derek B; Lawrence, A J; Sánchez, Erik J

    2010-12-10

    We present the development of a versatile spectroscopic imaging tool to allow for imaging with single-molecule sensitivity and high spatial resolution. The microscope allows for near-field and subdiffraction-limited far-field imaging by integrating a shear-force microscope on top of a custom inverted microscope design. The instrument has the ability to image in ambient conditions with optical resolutions on the order of tens of nanometers in the near field. A single low-cost computer controls the microscope with a field programmable gate array data acquisition card. High spatial resolution imaging is achieved with an inexpensive CW multiphoton excitation source, using an apertureless probe and simplified optical pathways. The high-resolution, combined with high collection efficiency and single-molecule sensitive optical capabilities of the microscope, are demonstrated with a low-cost CW laser source as well as a mode-locked laser source.

  18. Spectroscopic techniques (Moessbauer spectrometry, NMR, ESR...) as tools to resolve doubtful NMR images: Study of the craniopharyngioma tumor

    Rimbert, J.N.; Dumas, F.; Lafargue, C.; Kellershohn, C.; Brunelle, F.; Lallemand, D.

    1990-01-01

    Craniopharyngioma, an intracranial tumor, exhibits hyperintensity in the Spin-Echo-T 2 -NMR image and a hyposignal in the SE-T 1 -image. However, in some cases (15-20% cases), hypersignals are seen in both SE-T 1 and T 2 -MRI. Using spectroscopic techniques, Moessbauer spectrometry in particular, we have demonstrated that the T 1 hypersignal is due to ferritin, dissolved in the cystic liquid, after tumor cell lysis, in the course of time. Other possible reasons inducing a shortening of the T 1 relaxation time (presence of lipids, intratumoral hemorrhage) have been rejected. (orig.)

  19. Solar Resource Assessment with Sky Imagery and a Virtual Testbed for Sky Imager Solar Forecasting

    Kurtz, Benjamin Bernard

    In recent years, ground-based sky imagers have emerged as a promising tool for forecasting solar energy on short time scales (0 to 30 minutes ahead). Following the development of sky imager hardware and algorithms at UC San Diego, we present three new or improved algorithms for sky imager forecasting and forecast evaluation. First, we present an algorithm for measuring irradiance with a sky imager. Sky imager forecasts are often used in conjunction with other instruments for measuring irradiance, so this has the potential to decrease instrumentation costs and logistical complexity. In particular, the forecast algorithm itself often relies on knowledge of the current irradiance which can now be provided directly from the sky images. Irradiance measurements are accurate to within about 10%. Second, we demonstrate a virtual sky imager testbed that can be used for validating and enhancing the forecast algorithm. The testbed uses high-quality (but slow) simulations to produce virtual clouds and sky images. Because virtual cloud locations are known, much more advanced validation procedures are possible with the virtual testbed than with measured data. In this way, we are able to determine that camera geometry and non-uniform evolution of the cloud field are the two largest sources of forecast error. Finally, with the assistance of the virtual sky imager testbed, we develop improvements to the cloud advection model used for forecasting. The new advection schemes are 10-20% better at short time horizons.

  20. Spectroscopic Observations of Magnetic Reconnection and Chromospheric Evaporation in an X-shaped Solar Flare

    Li, Y.; Gan, W. Q. [Key Laboratory of Dark Matter and Space Astronomy, Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China); Kelly, M.; Qiu, J. [Department of Physics, Montana State University, Bozeman, MT 59717 (United States); Ding, M. D. [School of Astronomy and Space Science, Nanjing University, Nanjing 210023 (China); Zhu, X. S. [CAS Key Laboratory of Solar Activity, National Astronomical Observatories, Beijing 100012 (China)

    2017-10-20

    We present observations of distinct UV spectral properties at different locations during an atypical X-shaped flare (SOL2014-11-09T15:32) observed by the Interface Region Imaging Spectrograph ( IRIS ). In this flare, four chromospheric ribbons appear and converge at an X-point where a separator is anchored. Above the X-point, two sets of non-coplanar coronal loops approach laterally and reconnect at the separator. The IRIS slit was located close to the X-point, cutting across some of the flare ribbons and loops. Near the location of the separator, the Si iv 1402.77 Å line exhibits significantly broadened line wings extending to 200 km s{sup −1} with an unshifted line core. These spectral features suggest the presence of bidirectional flows possibly related to the separator reconnection. While at the flare ribbons, the hot Fe xxi 1354.08 Å line shows blueshifts and the cool Si iv 1402.77 Å, C ii 1335.71 Å, and Mg ii 2803.52 Å lines show evident redshifts up to a velocity of 80 km s{sup −1}, which are consistent with the scenario of chromospheric evaporation/condensation.

  1. Early detection of chemotherapy-refractory patients by monitoring textural alterations in diffuse optical spectroscopic images

    Sadeghi-Naini, Ali; Falou, Omar; Czarnota, Gregory J., E-mail: Gregory.Czarnota@sunnybrook.ca [Physical Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Department of Medical Biophysics, University of Toronto, Toronto, Ontario M4N 3M5 (Canada); Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario M4N 3M5 (Canada); Vorauer, Eric [Department of Medical Physics, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Department of Physics, Ryerson University, Toronto, Ontario M5B 2K3 (Canada); Chin, Lee [Department of Radiation Oncology, University of Toronto, Toronto, Ontario M4N 3M5 (Canada); Department of Medical Physics, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Department of Physics, Ryerson University, Toronto, Ontario M5B 2K3 (Canada); Tran, William T. [Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Wright, Frances C. [Division of General Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Department of Surgery, University of Toronto, Toronto, Ontario M4N 3M5 (Canada); Gandhi, Sonal [Division of Medical Oncology, Sunnybrook Health Sciences Centre, and Faculty of Medicine, University of Toronto, Toronto, Ontario M4N 3M5 (Canada); Yaffe, Martin J. [Physical Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5 (Canada); Department of Medical Biophysics, University of Toronto, Toronto, Ontario M4N 3M5 (Canada)

    2015-11-15

    Purpose: Changes in textural characteristics of diffuse optical spectroscopic (DOS) functional images, accompanied by alterations in their mean values, are demonstrated here for the first time as early surrogates of ultimate treatment response in locally advanced breast cancer (LABC) patients receiving neoadjuvant chemotherapy (NAC). NAC, as a standard component of treatment for LABC patient, induces measurable heterogeneous changes in tumor metabolism which were evaluated using DOS-based metabolic maps. This study characterizes such inhomogeneous nature of response development, by determining alterations in textural properties of DOS images apparent at early stages of therapy, followed later by gross changes in mean values of these functional metabolic maps. Methods: Twelve LABC patients undergoing NAC were scanned before and at four times after treatment initiation, and tomographic DOS images were reconstructed at each time. Ultimate responses of patients were determined clinically and pathologically, based on a reduction in tumor size and assessment of residual tumor cellularity. The mean-value parameters and textural features were extracted from volumetric DOS images for several functional and metabolic parameters prior to the treatment initiation. Changes in these DOS-based biomarkers were also monitored over the course of treatment. The measured biomarkers were applied to differentiate patient responses noninvasively and compared to clinical and pathologic responses. Results: Responding and nonresponding patients demonstrated different changes in DOS-based textural and mean-value parameters during chemotherapy. Whereas none of the biomarkers measured prior the start of therapy demonstrated a significant difference between the two patient populations, statistically significant differences were observed at week one after treatment initiation using the relative change in contrast/homogeneity of seven functional maps (0.001 < p < 0.049), and mean value of water

  2. Multi-voxel MR spectroscopic imaging of the brain: utility in clinical setting-initial results

    Parmar, Hemant; Lim, Tchoyoson C.C.; Yin Hong; Chua, Violet; Khin, Lay-Wai; Raidy, Tom; Hui, Francis

    2005-01-01

    Background and purpose: Compared to single voxel methods, MR spectroscopic imaging (MRSI) of the brain provides metabolic information with improved anatomical coverage and spectral resolution, but may be difficult to perform in the clinical setting. We evaluate the factors influencing spectral quality in MRSI using a semi-automated method, focussing on lipid contamination, and phase correction errors related to magnetic field inhomogeneity. Methods: We retrospectively analysed MRSI studies planned by radiologists and radiographers. Two-dimensional MRSI studies using point-resolved spectroscopy (PRESS) localisation, at long echo time (135 or 144 ms) were acquired on a 1.5 T scanner. Studies that contained lipid contamination and abnormally inverted spectra were reviewed and the latter correlated with anatomic location at the base of skull, and with the area of the region of interest (ROI) studied. Results: Of 128 consecutive MRSI studies, six showed abnormal inverted spectra, of which four were acquired at the base of skull. Multivariate logistic regression analysis showed that study location at the base of skull, but not larger ROI, was a significant predictor for the risk of being affected by inverted spectra (RR for base of skull: 11.76, 95% CI: 1.86-74.18, P = 0.009. RR for area of ROI: 3.68, 95% CI: 0.57-23.67, P = 0.170). Seven studies showed lipid contamination; all were in close proximity to the overlying scalp. Conclusion: Using a semi-automated acquisition and post-processing method, MRSI can be successfully applied in the clinical setting. However, care should be taken to avoid regions of high magnetic field inhomogeneity at the base of skull, and lipid contamination in voxels prescribed near the scalp

  3. Electronic structure of the cuprate superconducting and pseudogap phases from spectroscopic imaging STM

    Schmidt, A. R.; Fujita, K.; Kim, E.-A.; Lawler, M. J.; Eisaki, H.; Uchida, S.; Lee, D.-H.; Davis, J. C.

    2011-06-01

    We survey the use of spectroscopic imaging scanning tunneling microscopy (SI-STM) to probe the electronic structure of underdoped cuprates. Two distinct classes of electronic states are observed in both the d-wave superconducting (dSC) and the pseudogap (PG) phases. The first class consists of the dispersive Bogoliubov quasiparticle excitations of a homogeneous d-wave superconductor, existing below a lower energy scale E=Δ0. We find that the Bogoliubov quasiparticle interference (QPI) signatures of delocalized Cooper pairing are restricted to a k-space arc, which terminates near the lines connecting k=±(π/a0,0) to k=±(0,π/a0). This arc shrinks continuously with decreasing hole density such that Luttinger's theorem could be satisfied if it represents the front side of a hole-pocket that is bounded behind by the lines between k=±(π/a0,0) and k=±(0,π/a0). In both phases, the only broken symmetries detected for the |E|modulations, locally breaking both rotational and translational symmetries, coexist with this intra-unit-cell electronic symmetry breaking at E=Δ1. Their characteristic wavevector Q is determined by the k-space points where Bogoliubov QPI terminates and therefore changes continuously with doping. The distinct broken electronic symmetry states (intra-unit-cell and finite Q) coexisting at E~Δ1 are found to be indistinguishable in the dSC and PG phases. The next challenge for SI-STM studies is to determine the relationship of the E~Δ1 broken symmetry electronic states with the PG phase, and with the E<Δ0 states associated with Cooper pairing.

  4. Spectroscopic investigation of new fullerene based acceptors for organic solar cells; Spektroskopische Untersuchung neuartiger Fullerenakzeptoren fuer organische Solarzellen

    Liedte, Moritz Nils

    2012-04-27

    high open circuit voltage of 835 mV in the devices produced, but also a rather low current density. I tried to understand the processes in the charge carrier generation and extraction process causing this. Using several measurement techniques, combined with general knowledge about comparable endohedral fullerenes from the literature, I was able to identify an internal charge transfer of electrons from the lutetium atoms encaged in the C{sub 80} to the fullerene bulk as origin The results presented in this work give further indications for the advantages of using C{sub 70} based fullerene acceptors in organic solar cells to raise the total power conversion efficiencies of these devices, despite the higher production costs. The identification of anion signatures of different fullerenes show an additional method to monitor the excitation processes by optical spectroscopy in bulk-heterojunction devices. My research regarding the Lu{sub 3}N rate at C{sub 80} molecule showed a general effect regarding this class of molecules, that will be important for any further synthesizes or application of such molecules in organic photovoltaics. While the projects regarding the dimer acceptors and the Lu{sub 3}N rate at C{sub 80} molecule were completed in this work, the analysis of spectroscopic anion signatures left some open questions, especially for large fullerenes. Further investigations using spin sensitive or time resolved techniques, as available in our research group, could be useful to gather more detailed information on this topic. Also trying to get some PC{sub 81}BM for photoinduced absorption measurements, alone and in blend with several polymers, might be another way to energetically pinpoint the anion signature on C{sub 80}.

  5. Three-dimensional magnetic resonance spectroscopic imaging in the substantia nigra of healthy controls and patients with Parkinson's disease

    Groeger, Adriane; Godau, Jana; Berg, Daniela; Chadzynski, Grzegorz; Klose, Uwe

    2011-01-01

    To investigate the substantia nigra in patients with Parkinson's disease three-dimensional magnetic resonance spectroscopic imaging with high spatial resolution at 3 Tesla was performed. Regional variations of spectroscopic data between the rostral and caudal regions of the substantia nigra as well as the midbrain tegmentum areas were evaluated in healthy controls and patients with Parkinson's disease. Nine patients with Parkinson's disease and eight age- and gender-matched healthy controls were included in this study. Data were acquired by using three-dimensional magnetic resonance spectroscopic imaging measurements. The ratios between rostral and caudal voxels of the substantia nigra as well as the midbrain tegmentum areas were calculated for the main-metabolites N-acetyl aspartate, creatine, choline, and myo-inositol. Additionally, the metabolite/creatine ratios were calculated. In all subjects spectra of acceptable quality could be obtained with a nominal voxel size of 0.252 ml. The calculated rostral-to-caudal ratios of the metabolites as well as of the metabolite/creatine ratios showed with exception of choline/creatine ratio significant differences between healthy controls and patients with Parkinson's disease. The findings from this study indicate that regional variations in N-acetyl aspartate/creatine ratios in the regions of the substantia nigra may differentiate patients with Parkinson's disease and healthy controls. (orig.)

  6. Imaging Observations of Magnetic Reconnection in a Solar Eruptive Flare

    Li, Y.; Ding, M. D.; Sun, X.; Qiu, J.; Priest, E. R.

    2017-01-01

    Solar flares are among the most energetic events in the solar atmosphere. It is widely accepted that flares are powered by magnetic reconnection in the corona. An eruptive flare is usually accompanied by a coronal mass ejection, both of which are probably driven by the eruption of a magnetic flux rope (MFR). Here we report an eruptive flare on 2016 March 23 observed by the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory . The extreme-ultraviolet imaging observations exhibit the clear rise and eruption of an MFR. In particular, the observations reveal solid evidence of magnetic reconnection from both the corona and chromosphere during the flare. Moreover, weak reconnection is observed before the start of the flare. We find that the preflare weak reconnection is of tether-cutting type and helps the MFR to rise slowly. Induced by a further rise of the MFR, strong reconnection occurs in the rise phases of the flare, which is temporally related to the MFR eruption. We also find that the magnetic reconnection is more of 3D-type in the early phase, as manifested in a strong-to-weak shear transition in flare loops, and becomes more 2D-like in the later phase, as shown by the apparent rising motion of an arcade of flare loops.

  7. Imaging Observations of Magnetic Reconnection in a Solar Eruptive Flare

    Li, Y.; Ding, M. D. [School of Astronomy and Space Science, Nanjing University, Nanjing 210023 (China); Sun, X. [W. W. Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94305 (United States); Qiu, J. [Department of Physics, Montana State University, Bozeman, MT 59717 (United States); Priest, E. R., E-mail: yingli@nju.edu.cn [School of Mathematics and Statistics, University of St Andrews, Fife KY16 9SS, Scotland (United Kingdom)

    2017-02-01

    Solar flares are among the most energetic events in the solar atmosphere. It is widely accepted that flares are powered by magnetic reconnection in the corona. An eruptive flare is usually accompanied by a coronal mass ejection, both of which are probably driven by the eruption of a magnetic flux rope (MFR). Here we report an eruptive flare on 2016 March 23 observed by the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory . The extreme-ultraviolet imaging observations exhibit the clear rise and eruption of an MFR. In particular, the observations reveal solid evidence of magnetic reconnection from both the corona and chromosphere during the flare. Moreover, weak reconnection is observed before the start of the flare. We find that the preflare weak reconnection is of tether-cutting type and helps the MFR to rise slowly. Induced by a further rise of the MFR, strong reconnection occurs in the rise phases of the flare, which is temporally related to the MFR eruption. We also find that the magnetic reconnection is more of 3D-type in the early phase, as manifested in a strong-to-weak shear transition in flare loops, and becomes more 2D-like in the later phase, as shown by the apparent rising motion of an arcade of flare loops.

  8. Multi-slice echo-planar spectroscopic MR imaging provides both global and local metabolite measures in multiple sclerosis

    Mathiesen, Henrik Kahr; Tscherning, Thomas; Sorensen, Per Soelberg

    2005-01-01

    MR spectroscopy (MRS) provides information about neuronal loss or dysfunction by measuring decreases in N-acetyl aspartate (NAA), a metabolite widely believed to be a marker of neuronal viability. In multiple sclerosis (MS), whole-brain NAA (WBNAA) has been suggested as a marker of disease...... progression and treatment efficacy in treatment trials, and the ability to measure NAA loss in specific brain regions early in the evolution of this disease may have prognostic value. Most spectroscopic studies to date have been limited to single voxels or nonlocalized measurements of WBNAA only......, measurements of metabolites in specific brain areas chosen after image acquisition (e.g., normal-appearing white matter (NAWM), gray matter (GM), and lesions) can be obtained. The identification and exclusion of regions that are inadequate for spectroscopic evaluation in global assessments can significantly...

  9. Multimodality imaging using proton magnetic resonance spectroscopic imaging and 18F-fluorodeoxyglucose-positron emission tomography in local prostate cancer

    Shukla-Dave, Amita; Wassberg, Cecilia; Pucar, Darko; Schöder, Heiko; Goldman, Debra A; Mazaheri, Yousef; Reuter, Victor E; Eastham, James; Scardino, Peter T; Hricak, Hedvig

    2017-01-01

    AIM To assess the relationship using multimodality imaging between intermediary citrate/choline metabolism as seen on proton magnetic resonance spectroscopic imaging (1H-MRSI) and glycolysis as observed on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in prostate cancer (PCa) patients. METHODS The study included 22 patients with local PCa who were referred for endorectal magnetic resonance imaging/1H-MRSI (April 2002 to July 2007) and 18F-FDG-PET/CT and then underwent prostatectomy as primary or salvage treatment. Whole-mount step-section pathology was used as the standard of reference. We assessed the relationships between PET parameters [standardized uptake value (SUVmax and SUVmean)] and MRSI parameters [choline + creatine/citrate (CC/Cmax and CC/Cmean) and total number of suspicious voxels] using spearman’s rank correlation, and the relationships of PET and 1H-MRSI index lesion parameters to surgical Gleason score. RESULTS Abnormal intermediary metabolism on 1H-MRSI was present in 21/22 patients, while abnormal glycolysis on 18F-FDG-PET/CT was detected in only 3/22 patients. Specifically, index tumor localization rates were 0.95 (95%CI: 0.77-1.00) for 1H-MRSI and 0.14 (95%CI: 0.03-0.35) for 18F-FDG-PET/CT. Spearman rank correlations indicated little relationship (ρ = -0.36-0.28) between 1H-MRSI parameters and 18F-FDG-PET/CT parameters. Both the total number of suspicious voxels (ρ = 0.55, P = 0.0099) and the SUVmax (ρ = 0.46, P = 0.0366) correlated weakly with the Gleason score. No significant relationship was found between the CC/Cmax, CC/Cmean or SUVmean and the Gleason score (P = 0.15-0.79). CONCLUSION The concentration of intermediary metabolites detected by 1H MRSI and glycolytic flux measured 18F-FDG PET show little correlation. Furthermore, only few tumors were FDG avid on PET, possibly because increased glycolysis represents a late and rather ominous event in the progression of PCa. PMID:28396727

  10. Extra Solar Planetary Imaging Coronagraph and Science Requirements for the James Webb Telescope Observatory

    Clampin, Mark

    2004-01-01

    1) Extra solar planetary imaging coronagraph. Direct detection and characterization of Jovian planets, and other gas giants, in orbit around nearby stars is a necessary precursor to Terrestrial Planet Finder 0 in order to estimate the probability of Terrestrial planets in our stellar neighborhood. Ground based indirect methods are biased towards large close in Jovian planets in solar systems unlikely io harbor Earthlike planets. Thus to estimate the relative abundances of terrestrial planets and to determine optimal observing strategies for TPF a pathfinder mission would be desired. The Extra-Solar Planetary Imaging Coronagraph (EPIC) is such a pathfinder mission. Upto 83 stellar systems are accessible with a 1.5 meter unobscured telescope and coronagraph combination located at the Earth-Sun L2 point. Incorporating radiometric and angular resolution considerations show that Jovians could be directly detected (5 sigma) in the 0.5 - 1.0 micron band outside of an inner working distance of 5/D with integration times of -10 - 100 hours per observation. The primary considerations for a planet imager are optical wavefront quality due to manufacturing, alignment, structural and thermal considerations. pointing stability and control, and manufacturability of coronagraphic masks and stops to increase the planetary-to- stellar contrast and mitigate against straylight. Previously proposed coronagraphic concepts are driven to extreme tolerances. however. we have developed and studied a mission, telescope and coronagraphic detection concept, which is achievable in the time frame of a Discovery class NASA mission. 2) Science requirements for the James Webb Space Telescope observatory. The James Webb Space Observatory (JWST) is an infrared observatory, which will be launched in 201 1 to an orbit at L2. JWST is a segmented, 18 mirror segment telescope with a diameter of 6.5 meters, and a clear aperture of 25 mA2. The telescope is designed to conduct imaging and spectroscopic

  11. Cross-Sectional Transport Imaging in a Multijunction Solar Cell

    Haegel, Nancy M.; Ke, Chi-Wen; Taha, Hesham; Guthrey, Harvey; Fetzer, C. M.; King, Richard

    2015-06-14

    Combining highly localized electron-beam excitation at a point with the spatial resolution capability of optical near-field imaging, we have imaged carrier transport in a cross-sectioned multijunction (GaInP/GaInAs/Ge) solar cell. We image energy transport associated with carrier diffusion throughout the full width of the middle (GaInAs) cell and luminescent coupling from point excitation in the top cell GaInP to the middle cell. Supporting cathodoluminescence and near-field photoluminescence measurements demonstrate excitation-dependent Fermi level splitting effects that influence cross-sectioned spectroscopy results as well as transport limitations on the spatial resolution of cross-sectional measurements.

  12. Ground-based multi-station spectroscopic imaging with ALIS. - Scientific highlights, project status and future prospects

    Brändström; Gustavsson, Björn; Pellinen-Wannberg, Asta; Sandahl, Ingrid; Sergienko, Tima; Steen, Ake

    2005-08-01

    The Auroral Large Imaging System (ALIS) was first proposed at the ESA-PAC meeting in Lahnstein 1989. The first spectroscopic imaging station was operational in 1994, and since then up to six stations have been in simultaneous operation. Each station has a scientific-grade CCD-detector and a filter-wheel for narrow-band interference-filters with six positions. The field-of-view is around 70°. Each imager is mounted in a positioning system, enabling imaging of a common volume from several sites. This enables triangulation and tomography. Raw data from ALIS is freely available at ("http://alis.irf.se") and ALIS is open for scientific colaboration. ALIS made the first unambiguous observations of Radio-induced optical emissions at high latitudes, and the detection of water in a Leonid meteor-trail. Both rockets and satellite coordination are considered for future observations with ALIS.

  13. Synchrotron X-ray imaging applied to solar photovoltaic silicon

    Lafford, T A; Villanova, J; Plassat, N; Dubois, S; Camel, D

    2013-01-01

    Photovoltaic (PV) cell performance is dictated by the material of the cell, its quality and purity, the type, quantity, size and distribution of defects, as well as surface treatments, deposited layers and contacts. A synchrotron offers unique opportunities for a variety of complementary X-ray techniques, given the brilliance, spectrum, energy tunability and potential for (sub-) micron-sized beams. Material properties are revealed within in the bulk and at surfaces and interfaces. X-ray Diffraction Imaging (X-ray Topography), Rocking Curve Imaging and Section Topography reveal defects such as dislocations, inclusions, misorientations and strain in the bulk and at surfaces. Simultaneous measurement of micro-X-Ray Fluorescence (μ-XRF) and micro-X-ray Beam Induced Current (μ-XBIC) gives direct correlation between impurities and PV performance. Together with techniques such as microscopy and Light Beam Induced Current (LBIC) measurements, the correlation between structural properties and photovoltaic performance can be deduced, as well as the relative influence of parameters such as defect type, size, spatial distribution and density (e.g [1]). Measurements may be applied at different stages of solar cell processing in order to follow the evolution of the material and its properties through the manufacturing process. Various grades of silicon are under study, including electronic and metallurgical grades in mono-crystalline, multi-crystalline and mono-like forms. This paper aims to introduce synchrotron imaging to non-specialists, giving example results on selected solar photovoltaic silicon samples.

  14. High-definition Fourier Transform Infrared (FT-IR) Spectroscopic Imaging of Human Tissue Sections towards Improving Pathology

    Nguyen, Peter L.; Davidson, Bennett; Akkina, Sanjeev; Guzman, Grace; Setty, Suman; Kajdacsy-Balla, Andre; Walsh, Michael J.

    2015-01-01

    High-definition Fourier Transform Infrared (FT-IR) spectroscopic imaging is an emerging approach to obtain detailed images that have associated biochemical information. FT-IR imaging of tissue is based on the principle that different regions of the mid-infrared are absorbed by different chemical bonds (e.g., C=O, C-H, N-H) within cells or tissue that can then be related to the presence and composition of biomolecules (e.g., lipids, DNA, glycogen, protein, collagen). In an FT-IR image, every pixel within the image comprises an entire Infrared (IR) spectrum that can give information on the biochemical status of the cells that can then be exploited for cell-type or disease-type classification. In this paper, we show: how to obtain IR images from human tissues using an FT-IR system, how to modify existing instrumentation to allow for high-definition imaging capabilities, and how to visualize FT-IR images. We then present some applications of FT-IR for pathology using the liver and kidney as examples. FT-IR imaging holds exciting applications in providing a novel route to obtain biochemical information from cells and tissue in an entirely label-free non-perturbing route towards giving new insight into biomolecular changes as part of disease processes. Additionally, this biochemical information can potentially allow for objective and automated analysis of certain aspects of disease diagnosis. PMID:25650759

  15. GAP: yet another image processing system for solar observations.

    Keller, C. U.

    GAP is a versatile, interactive image processing system for analyzing solar observations, in particular extended time sequences, and for preparing publication quality figures. It consists of an interpreter that is based on a language with a control flow similar to PASCAL and C. The interpreter may be accessed from a command line editor and from user-supplied functions, procedures, and command scripts. GAP is easily expandable via external FORTRAN programs that are linked to the GAP interface routines. The current version of GAP runs on VAX, DECstation, Sun, and Apollo computers. Versions for MS-DOS and OS/2 are in preparation.

  16. Imaging, scattering, and spectroscopic systems for biomedical optics: Tools for bench top and clinical applications

    Cottrell, William J.

    Optical advances have had a profound impact on biology and medicine. The capabilities range from sensing biological analytes to whole animal and subcellular imaging and clinical therapies. The work presented in this thesis describes three independent and multifunctional optical systems, which explore clinical therapy at the tissue level, biological structure at the cell/organelle level, and the function of underlying fundamental cellular processes. First, we present a portable clinical instrument for delivering delta-aminolevulinic acid photodynamic therapy (ALA-PDT) while performing noninvasive spectroscopic monitoring in vivo. Using an off-surface probe, the instrument delivered the treatment beam to a user-defined field on the skin and performed reflectance and fluorescence spectroscopies at two regions within this field. The instrument was used to monitor photosensitizer fluorescence photobleaching, fluorescent photoproduct kinetics, and blood oxygen saturation during a clinical ALA-PDT trial on superficial basal cell carcinoma (sBCC). Protoporphyrin IX and photoproduct fluorescence excited by the 632.8 nm PDT treatment laser was collected between 665 and 775 nm. During a series of brief treatment interruptions at programmable time points, white-light reflectance spectra between 475 and 775 nm were acquired. Fluorescence spectra were corrected for the effects of absorption and scattering, informed by the reflectance measurements, and then decomposed into known fluorophore contributions in real time using a robust singular-value decomposition fitting routine. Reflectance spectra additionally provided information on hemoglobin oxygen saturation. We next describe the incorporation of this instrument into clinical trials at Roswell Park Cancer Institute (Buffalo, NY). In this trial we examined the effects of light irradiance on photodynamic efficiency and pain. The rate of singlet-oxygen production depends on the product of irradiance and photosensitizer and oxygen

  17. High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data.

    Bhargava, Rohit; Fernandez, Daniel C; Hewitt, Stephen M; Levin, Ira W

    2006-07-01

    Vibrational spectroscopy allows a visualization of tissue constituents based on intrinsic chemical composition and provides a potential route to obtaining diagnostic markers of diseases. Characterizations utilizing infrared vibrational spectroscopy, in particular, are conventionally low throughput in data acquisition, generally lacking in spatial resolution with the resulting data requiring intensive numerical computations to extract information. These factors impair the ability of infrared spectroscopic measurements to represent accurately the spatial heterogeneity in tissue, to incorporate robustly the diversity introduced by patient cohorts or preparative artifacts and to validate developed protocols in large population studies. In this manuscript, we demonstrate a combination of Fourier transform infrared (FTIR) spectroscopic imaging, tissue microarrays (TMAs) and fast numerical analysis as a paradigm for the rapid analysis, development and validation of high throughput spectroscopic characterization protocols. We provide an extended description of the data treatment algorithm and a discussion of various factors that may influence decision-making using this approach. Finally, a number of prostate tissue biopsies, arranged in an array modality, are employed to examine the efficacy of this approach in histologic recognition of epithelial cell polarization in patients displaying a variety of normal, malignant and hyperplastic conditions. An index of epithelial cell polarization, derived from a combined spectral and morphological analysis, is determined to be a potentially useful diagnostic marker.

  18. In vivo measurement of regional brain metabolic response to hyperventilation using magnetic resonance: proton echo planar spectroscopic imaging (PEPSI).

    Posse, S; Dager, S R; Richards, T L; Yuan, C; Ogg, R; Artru, A A; Müller-Gärtner, H W; Hayes, C

    1997-06-01

    A new rapid spectroscopic imaging technique with improved sensitivity and lipid suppression, referred to as Proton Echo Planar Spectroscopic Imaging (PEPSI), has been developed to measure the 2-dimensional distribution of brain lactate increases during hyperventilation on a conventional clinical scanner equipped with a head surface coil phased array. PEPSI images (nominal voxel size: 1.125 cm3) in five healthy subjects from an axial section approximately 20 mm inferior to the intercommissural line were obtained during an 8.5-min baseline period of normocapnia and during the final 8.5 min of a 10-min period of capnometry-controlled hyperventilation (end-tidal PCO2 of 20 mmHg). The lactate/N-acetyl aspartate signal increased significantly from baseline during hyperventilation for the insular cortex, temporal cortex, and occipital regions of both the right and left hemisphere, but not in the basal ganglia. Regional or hemispheric right-to-left differences were not found. The study extends previous work using single-voxel MR spectroscopy to dynamically study hyperventilation effects on brain metabolism.

  19. Three dimensional proton MR spectroscopic imaging in transition zone prostate cancer

    Yang Yi; Zhao Wenlu; Shen Junkang

    2012-01-01

    Objective: To discuss the clinical value of three dimensional proton MR spectroscopic imaging (3D 1 HMRSI) in the detection of transition zone (TZ) prorate cancer and evaluate the feasibility of 3D 1 HMRSI for determining the aggressiveness of TZ cancer by analyzing its metabolic characteristics. Methods: The 3D 1 HMRSI data of sixty patients suspected TZ cancer in conventional MR examinations were retrospectively analyzed. The values of (Cho + Cre)/Cit of TZ cancer and benign prostatic hyperplasia (BPH) voxels were recorded and compared using independent sample t' test, and the area under the ROC curve was used to evaluate the diagnostic accuracy. Based on Gleason scores, TZ cancer voxels were divided into three groups,including low-risk (Gleason score <7), intermediate-risk (Gleason score =7) and high-risk (Gleason score >7). The values of (Cho + Cre)/Cit were compared among the three groups using Kruskal-Wallis test. The correlation of the value of (Cho + Cre)/Cit and Gleason score was analyzed using rank correlation analysis. Results: Among the 60 patients, histopathology confirmed TZ cancer in 25 patients and BPH in 35 patients. The inversion of Cho and Cit peak value with increased (Cho + Cre)/Cit was detected in 160 out of 177 TZ cancer voxels. Most spectral curves of the 517 BPH voxels were similar with that of normal peripheral zone on 1 HMRSI. The mean values of (Cho + Cre)/Cit of TZ cancer and BPH voxels were 2.17 ± 1.29 and 0.77 ± 0.20, respectively, with significant difference between them (t'=14.38, P<0.01). Using (Cho + Cre)/Cit for distinguishing TZ cancer, the area under ROC curve was 0.985 (P<0.01).With the cut-off point 1.08, the sensitivity, specificity and accuracy of TZ cancer diagnosis was 92.7%, 94.2% and 93.8%, respectively. The number of low-risk, intermediate-risk and high-risk TZ cancer voxels were 57, 64 and 56 respectively, and the mean values of (Cho + Cre)/Cit of the three groups were 1.43 (1.16-1.87), 1.66 (1

  20. OBSERVING THE FINE STRUCTURE OF LOOPS THROUGH HIGH-RESOLUTION SPECTROSCOPIC OBSERVATIONS OF CORONAL RAIN WITH THE CRISP INSTRUMENT AT THE SWEDISH SOLAR TELESCOPE

    Antolin, P.; Rouppe van der Voort, L.

    2012-01-01

    Observed in cool chromospheric lines, such as Hα or Ca II H, coronal rain corresponds to cool and dense plasma falling from coronal heights. Considered as a peculiar sporadic phenomenon of active regions, it has not received much attention since its discovery more than 40 years ago. Yet, it has been shown recently that a close relationship exists between this phenomenon and the coronal heating mechanism. Indeed, numerical simulations have shown that this phenomenon is most likely due to a loss of thermal equilibrium ensuing from a heating mechanism acting mostly toward the footpoints of loops. We present here one of the first high-resolution spectroscopic observations of coronal rain, performed with the CRisp Imaging Spectro Polarimeter (CRISP) instrument at the Swedish Solar Telescope. This work constitutes the first attempt to assess the importance of coronal rain in the understanding of the coronal magnetic field in active regions. With the present resolution, coronal rain is observed to literally invade the entire field of view. A large statistical set is obtained in which dynamics (total velocities and accelerations), shapes (lengths and widths), trajectories (angles of fall of the blobs), and thermodynamic properties (temperatures) of the condensations are derived. Specifically, we find that coronal rain is composed of small and dense chromospheric cores with average widths and lengths of ∼310 km and ∼710 km, respectively, average temperatures below 7000 K, displaying a broad distribution of falling speeds with an average of ∼70 km s –1 , and accelerations largely below the effective gravity along loops. Through estimates of the ion-neutral coupling in the blobs we show that coronal rain acts as a tracer of the coronal magnetic field, thus supporting the multi-strand loop scenario, and acts as a probe of the local thermodynamic conditions in loops. We further elucidate its potential in coronal heating. We find that the cooling in neighboring strands

  1. Dynamic Spectral Imaging of Decimetric Fiber Bursts in an Eruptive Solar Flare

    Wang, Zhitao; Chen, Bin; Gary, Dale E., E-mail: zw56@njit.edu [Center for Solar-Terrestrial Research, New Jersey Institute of Technology, University Heights, Newark, NJ 07102 (United States)

    2017-10-20

    Fiber bursts are a type of fine structure that is often superposed on type IV radio continuum emission during solar flares. Although studied for many decades, its physical exciter, emission mechanism, and association with the flare energy release remain unclear, partly due to the lack of simultaneous imaging observations. We report the first dynamic spectroscopic imaging observations of decimetric fiber bursts, which occurred during the rise phase of a long-duration eruptive flare on 2012 March 3, as obtained by the Karl G. Jansky Very Large Array in 1–2 GHz. Our results show that the fiber sources are located near and above one footpoint of the flare loops. The fiber source and the background continuum source are found to be co-spatial and share the same morphology. It is likely that they are associated with nonthermal electrons trapped in the converging magnetic fields near the footpoint, as supported by a persistent coronal hard X-ray source present during the flare rise phase. We analyze three groups of fiber bursts in detail with dynamic imaging spectroscopy and obtain their mean frequency-dependent centroid trajectories in projection. By using a barometric density model and magnetic field based on a potential field extrapolation, we further reconstruct the 3D source trajectories of fiber bursts, for comparison with expectations from the whistler wave model and two MHD-based models. We conclude that the observed fiber burst properties are consistent with an exciter moving at the propagation velocity expected for whistler waves, or models that posit similar exciter velocities.

  2. Application of second derivative spectroscopy for increasing molecular specificity of Fourier transform infrared spectroscopic imaging of articular cartilage.

    Rieppo, L; Saarakkala, S; Närhi, T; Helminen, H J; Jurvelin, J S; Rieppo, J

    2012-05-01

    Fourier transform infrared (FT-IR) spectroscopic imaging is a promising method that enables the analysis of spatial distribution of biochemical components within histological sections. However, analysis of FT-IR spectroscopic data is complicated since absorption peaks often overlap with each other. Second derivative spectroscopy is a technique which enhances the separation of overlapping peaks. The objective of this study was to evaluate the specificity of the second derivative peaks for the main tissue components of articular cartilage (AC), i.e., collagen and proteoglycans (PGs). Histological bovine AC sections were measured before and after enzymatic removal of PGs. Both formalin-fixed sections (n = 10) and cryosections (n = 6) were investigated. Relative changes in the second derivative peak heights caused by the removal of PGs were calculated for both sample groups. The results showed that numerous peaks, e.g., peaks located at 1202 cm(-1) and 1336 cm(-1), altered less than 5% in the experiment. These peaks were assumed to be specific for collagen. In contrast, two peaks located at 1064 cm(-1) and 1376 cm(-1) were seen to alter notably, approximately 50% or more. These peaks were regarded to be specific for PGs. The changes were greater in cryosections than formalin-fixed sections. The results of this study suggest that the second derivative spectroscopy offers a practical and more specific method than routinely used absorption spectrum analysis methods to obtain compositional information on AC with FT-IR spectroscopic imaging. Copyright © 2012 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

  3. Organ-confined prostate cancer: effect of prior transrectal biopsy on endorectal MRI and MR spectroscopic imaging

    Qayyum, Aliya; Coakley, F.V.; Lu, Y.; Olpin, J.D.; Wu, L.; Yeh, B.M.; Carroll, P.R.; Kurhanewicz, J.

    2004-01-01

    Objective: Our aim was to determine the effect of prior transrectal biopsy on endorectal MRI and MR spectroscopic imaging findings in patients with organ-confined prostate cancer. Materials and Methods: Endorectal MRI and MR spectroscopic imaging were performed in 43 patients with biopsy-proven prostate cancer before radical prostatectomy confirming organ-confined disease. For each sextant, two independent reviewers scored the degree of hemorrhage on a scale from 1 to 5 and recorded the presence or absence of capsular irregularity. A spectroscopist recorded the number of spectrally degraded voxels in the peripheral zone. The outcome variables of capsular irregularity and spectral degradation were correlated with the predictor variables of time from biopsy and degree of hemorrhage after biopsy. Results: Capsular irregularity was unrelated to time from biopsy or to degree of hemorrhage. Spectral degradation was inversely related to time from biopsy (p < 0.01); the mean percentage of degraded peripheral zone voxels was 18.5% within 8 weeks of biopsy compared with 7% after 8 weeks. Spectral degradation was unrelated to the degree of hemorrhage. Conclusion: In organ-confined prostate cancer, capsular irregularity can be seen at any time after biopsy and is independent of the degree of hemorrhage, whereas spectral degradation is seen predominantly in the first 8 weeks after biopsy. MRI staging criteria and guidelines for scheduling studies after biopsy may require appropriate modification. (author)

  4. Image Quality in High-resolution and High-cadence Solar Imaging

    Denker, C.; Dineva, E.; Balthasar, H.; Verma, M.; Kuckein, C.; Diercke, A.; González Manrique, S. J.

    2018-03-01

    Broad-band imaging and even imaging with a moderate bandpass (about 1 nm) provides a photon-rich environment, where frame selection (lucky imaging) becomes a helpful tool in image restoration, allowing us to perform a cost-benefit analysis on how to design observing sequences for imaging with high spatial resolution in combination with real-time correction provided by an adaptive optics (AO) system. This study presents high-cadence (160 Hz) G-band and blue continuum image sequences obtained with the High-resolution Fast Imager (HiFI) at the 1.5-meter GREGOR solar telescope, where the speckle-masking technique is used to restore images with nearly diffraction-limited resolution. The HiFI employs two synchronized large-format and high-cadence sCMOS detectors. The median filter gradient similarity (MFGS) image-quality metric is applied, among others, to AO-corrected image sequences of a pore and a small sunspot observed on 2017 June 4 and 5. A small region of interest, which was selected for fast-imaging performance, covered these contrast-rich features and their neighborhood, which were part of Active Region NOAA 12661. Modifications of the MFGS algorithm uncover the field- and structure-dependency of this image-quality metric. However, MFGS still remains a good choice for determining image quality without a priori knowledge, which is an important characteristic when classifying the huge number of high-resolution images contained in data archives. In addition, this investigation demonstrates that a fast cadence and millisecond exposure times are still insufficient to reach the coherence time of daytime seeing. Nonetheless, the analysis shows that data acquisition rates exceeding 50 Hz are required to capture a substantial fraction of the best seeing moments, significantly boosting the performance of post-facto image restoration.

  5. Adaptation of Dunn Solar Telescope for Jovian Doppler spectro imaging

    Underwood, Thomas A.; Voelz, David; Schmider, François-Xavier; Jackiewicz, Jason; Dejonghe, Julien; Bresson, Yves; Hull, Robert; Goncalves, Ivan; Gualme, Patrick; Morand, Frédéric; Preis, Olivier

    2017-09-01

    This paper describes instrumentation used to adapt the Dunn Solar Telescope (DST) located on Sacramento Peak in Sunspot, NM for observations using the Doppler Spectro Imager (DSI). The DSI is based on a Mach-Zehnder interferometer and measures the Doppler shift of solar lines allowing for the study of atmospheric dynamics of giant planets and the detection of their acoustic oscillations. The instrumentation is being designed and built through a collaborative effort between a French team from the Observatoire de la Cote d'Azur (OCA) that designed the DSI and a US team at New Mexico State University (NMSU). There are four major components that couple the DSI to the DST: a guider/tracker, fast steering mirror (FSM), pupil stabilizer and transfer optics. The guider/tracker processes digital video to centroid-track the planet and outputs voltages to the DST's heliostat controls. The FSM removes wavefront tip/tilt components primarily due to turbulence and the pupil stabilizer removes any slow pupil "wander" introduced by the telescope's heliostat/turret arrangement. The light received at a science port of the DST is sent through the correction and stabilization components and into the DSI. The FSM and transfer optics designs are being provided by the OCA team and serve much the same functions as they do for other telescopes at which DSI observations have been conducted. The pupil stabilization and guider are new and are required to address characteristics of the DST.

  6. A systematic desaturation method for images from the Atmospheric Imaging Assembly in the Solar Dynamics Observatory.

    Torre, Gabriele; Schwartz, Richard; Piana, Michele; Massone, Anna Maria; Benvenuto, Federico

    2016-05-01

    The fine spatial resolution of the SDO AIA CCD's is often destroyed by the charge in saturated pixels overflowing into a swath of neighboring cells during fast rising solar flares. Automated exposure control can only mitigate this issue to a degree and it has other deleterious effects. Our method addresses the desaturation problem for AIA images as an image reconstruction problem in which the information content of the diffraction fringes, generated by the interaction between the incoming radiation and the hardware of the spacecraft, is exploited to recover the true image intensities within the primary saturated core of the image. This methodology takes advantage of some well defined techniques like cross-correlation and the Expectation Maximization method to invert the direct relation between the diffraction fringes intensities and the true flux intensities. During this talk a complete overview on the structure of the method will be provided, besides some reliability tests obtained by its application against synthetic and real data.

  7. AN INTERFACE REGION IMAGING SPECTROGRAPH FIRST VIEW ON SOLAR SPICULES

    Pereira, T. M. D.; De Pontieu, B.; Carlsson, M.; Hansteen, V. [Institute of Theoretical Astrophysics, University of Oslo, P.O. Box 1029 Blindern, NO-0315 Oslo (Norway); Tarbell, T. D.; Lemen, J.; Title, A.; Boerner, P.; Hurlburt, N.; Wülser, J. P.; Martínez-Sykora, J.; Kleint, L. [Lockheed Martin Solar and Astrophysics Laboratory, 3251 Hanover Street, Org. A021S, Bldg. 252, Palo Alto, CA 94304 (United States); Golub, L.; McKillop, S.; Reeves, K. K.; Saar, S.; Testa, P.; Tian, H. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Jaeggli, S.; Kankelborg, C., E-mail: tiago.pereira@astro.uio.no [Department of Physics, Montana State University, P.O. Box 173840, Bozeman, MT 59717 (United States)

    2014-09-01

    Solar spicules have eluded modelers and observers for decades. Since the discovery of the more energetic type II, spicules have become a heated topic but their contribution to the energy balance of the low solar atmosphere remains unknown. Here we give a first glimpse of what quiet-Sun spicules look like when observed with NASA's recently launched Interface Region Imaging Spectrograph (IRIS). Using IRIS spectra and filtergrams that sample the chromosphere and transition region, we compare the properties and evolution of spicules as observed in a coordinated campaign with Hinode and the Atmospheric Imaging Assembly. Our IRIS observations allow us to follow the thermal evolution of type II spicules and finally confirm that the fading of Ca II H spicules appears to be caused by rapid heating to higher temperatures. The IRIS spicules do not fade but continue evolving, reaching higher and falling back down after 500-800 s. Ca II H type II spicules are thus the initial stages of violent and hotter events that mostly remain invisible in Ca II H filtergrams. These events have very different properties from type I spicules, which show lower velocities and no fading from chromospheric passbands. The IRIS spectra of spicules show the same signature as their proposed disk counterparts, reinforcing earlier work. Spectroheliograms from spectral rasters also confirm that quiet-Sun spicules originate in bushes from the magnetic network. Our results suggest that type II spicules are indeed the site of vigorous heating (to at least transition region temperatures) along extensive parts of the upward moving spicular plasma.

  8. Accelerated proton echo planar spectroscopic imaging (PEPSI) using GRAPPA with a 32-channel phased-array coil.

    Tsai, Shang-Yueh; Otazo, Ricardo; Posse, Stefan; Lin, Yi-Ru; Chung, Hsiao-Wen; Wald, Lawrence L; Wiggins, Graham C; Lin, Fa-Hsuan

    2008-05-01

    Parallel imaging has been demonstrated to reduce the encoding time of MR spectroscopic imaging (MRSI). Here we investigate up to 5-fold acceleration of 2D proton echo planar spectroscopic imaging (PEPSI) at 3T using generalized autocalibrating partial parallel acquisition (GRAPPA) with a 32-channel coil array, 1.5 cm(3) voxel size, TR/TE of 15/2000 ms, and 2.1 Hz spectral resolution. Compared to an 8-channel array, the smaller RF coil elements in this 32-channel array provided a 3.1-fold and 2.8-fold increase in signal-to-noise ratio (SNR) in the peripheral region and the central region, respectively, and more spatial modulated information. Comparison of sensitivity-encoding (SENSE) and GRAPPA reconstruction using an 8-channel array showed that both methods yielded similar quantitative metabolite measures (P > 0.1). Concentration values of N-acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inositol (mI), and the sum of glutamate and glutamine (Glx) for both methods were consistent with previous studies. Using the 32-channel array coil the mean Cramer-Rao lower bounds (CRLB) were less than 8% for NAA, tCr, and Cho and less than 15% for mI and Glx at 2-fold acceleration. At 4-fold acceleration the mean CRLB for NAA, tCr, and Cho was less than 11%. In conclusion, the use of a 32-channel coil array and GRAPPA reconstruction can significantly reduce the measurement time for mapping brain metabolites. (c) 2008 Wiley-Liss, Inc.

  9. Ellerman bombs observed with the new vacuum solar telescope and the atmospheric imaging assembly onboard the solar dynamics observatory

    Chen, Yajie; Tian, Hui; Xu, Zhi; Xiang, Yongyuan; Fang, Yuliang; Yang, Zihao

    2017-12-01

    Ellerman bombs (EBs) are believed to be small-scale reconnection events occurring around the temperature minimum region in the solar atmosphere. They are often identified as significant enhancements in the extended Hα wings without obvious signatures in the Hα core. Here we explore the possibility of using the 1700 Å images taken by the Atmospheric Imaging Assembly (AIA) onboard the Solar Dynamics Observatory (SDO) to study EBs. From the Hα wing images obtained with the New Vacuum Solar Telescope (NVST) on 2015 May 2, we have identified 145 EBs and 51% of them clearly correspond to the bright points (BPs) in the AIA 1700 Å images. If we resize the NVST images using a linear interpolation to make the pixel sizes of the AIA and NVST images the same, some previously identified EBs disappear and about 71% of the remaining EBs are associated with BPs. Meanwhile, 66% of the compact brightenings in the AIA 1700 Å images can be identified as EBs in the Hα wings. The intensity enhancements of the EBs in the Hα wing images reveal a linear correlation with those of the BPs in the AIA 1700 Å images. Our study suggests that a significant fraction of EBs can be observed with the AIA 1700 Å filter, which is promising for large-sample statistical study of EBs as the seeing-free and full-disk SDO/AIA data are routinely available.

  10. Spectroscopic imaging of limiter heat and particle fluxes and the resulting impurity sources during Wendelstein 7-X startup plasmas.

    Stephey, L; Wurden, G A; Schmitz, O; Frerichs, H; Effenberg, F; Biedermann, C; Harris, J; König, R; Kornejew, P; Krychowiak, M; Unterberg, E A

    2016-11-01

    A combined IR and visible camera system [G. A. Wurden et al., "A high resolution IR/visible imaging system for the W7-X limiter," Rev. Sci. Instrum. (these proceedings)] and a filterscope system [R. J. Colchin et al., Rev. Sci. Instrum. 74, 2068 (2003)] were implemented together to obtain spectroscopic data of limiter and first wall recycling and impurity sources during Wendelstein 7-X startup plasmas. Both systems together provided excellent temporal and spatial spectroscopic resolution of limiter 3. Narrowband interference filters in front of the camera yielded C-III and H α photon flux, and the filterscope system provided H α , H β , He-I, He-II, C-II, and visible bremsstrahlung data. The filterscopes made additional measurements of several points on the W7-X vacuum vessel to yield wall recycling fluxes. The resulting photon flux from both the visible camera and filterscopes can then be compared to an EMC3-EIRENE synthetic diagnostic [H. Frerichs et al., "Synthetic plasma edge diagnostics for EMC3-EIRENE, highlighted for Wendelstein 7-X," Rev. Sci. Instrum. (these proceedings)] to infer both a limiter particle flux and wall particle flux, both of which will ultimately be used to infer the complete particle balance and particle confinement time τ P .

  11. Spectroscopic imaging of limiter heat and particle fluxes and the resulting impurity sources during Wendelstein 7-X startup plasmas

    Stephey, L., E-mail: stephey@wisc.edu; Schmitz, O.; Frerichs, H.; Effenberg, F. [University of Wisconsin–Madison, Madison, Wisconsin 53706 (United States); Wurden, G. A. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Biedermann, C.; König, R.; Kornejew, P.; Krychowiak, M. [Max-Planck-Institut für Plasma Physik, Wendelsteinstrasse 1, 17491 Greifswald (Germany); Harris, J.; Unterberg, E. A. [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States)

    2016-11-15

    A combined IR and visible camera system [G. A. Wurden et al., “A high resolution IR/visible imaging system for the W7-X limiter,” Rev. Sci. Instrum. (these proceedings)] and a filterscope system [R. J. Colchin et al., Rev. Sci. Instrum. 74, 2068 (2003)] were implemented together to obtain spectroscopic data of limiter and first wall recycling and impurity sources during Wendelstein 7-X startup plasmas. Both systems together provided excellent temporal and spatial spectroscopic resolution of limiter 3. Narrowband interference filters in front of the camera yielded C-III and H{sub α} photon flux, and the filterscope system provided H{sub α}, H{sub β}, He-I, He-II, C-II, and visible bremsstrahlung data. The filterscopes made additional measurements of several points on the W7-X vacuum vessel to yield wall recycling fluxes. The resulting photon flux from both the visible camera and filterscopes can then be compared to an EMC3-EIRENE synthetic diagnostic [H. Frerichs et al., “Synthetic plasma edge diagnostics for EMC3-EIRENE, highlighted for Wendelstein 7-X,” Rev. Sci. Instrum. (these proceedings)] to infer both a limiter particle flux and wall particle flux, both of which will ultimately be used to infer the complete particle balance and particle confinement time τ{sub P}.

  12. The SOLAR-C Mission

    Suematsu, Y.

    2015-12-01

    The Solar-C is a Japan-led international solar mission planned to be launched in mid2020. It is designed to investigate the magnetic activities of the Sun, focusing on the study in heating and dynamical phenomena of the chromosphere and corona, and also to develop an algorithm for predicting short and long term solar evolution. Since it has been revealed that the different parts of the magnetized solar atmosphere are essentially coupled, the SOLAR-C should tackle the spatial scales and temperature regimes that need to be observed in order to achieve a comprehensive physical understanding of this coupling. The science of Solar-C will greatly advance our understanding of the Sun, of basic physical processes operating throughout the universe. To dramatically improve the situation, SOLAR-C will carry three dedicated instruments; the Solar UV-Vis-IR Telescope (SUVIT), the EUV Spectroscopic Telescope (EUVST) and the High Resolution Coronal Imager (HCI), to jointly observe the entire visible solar atmosphere with essentially the same high spatial resolution (0.1-0.3 arcsec), performing high resolution spectroscopic measurements over all atmospheric regions and spectro-polarimetric measurements from the photosphere through the upper chromosphere. In addition, Solar-C will contribute to our understanding on the influence of the Sun-Earth environments with synergetic wide-field observations from ground-based and other space missions. Some leading science objectives and the mission concept, including designs of the three instruments aboard SOLAR-C will be presented.

  13. Spectroscopic Imaging Using Ge and CdTe Based Detector Systems for Hard X-ray Applications

    Astromskas, Vytautas

    Third generation synchrotron facilities such as the Diamond Light Source (DLS) have a wide range of experiments performed for a wide range of science fields. The DLS operates at energies up to 150 keV which introduces great challenges to radiation detector technology. This work focuses on the requirements that the detector technology faces for X-ray Absorption Fine Structure (XAFS) and powder diffraction experiments in I12 and I15 beam lines, respectively. A segmented HPGe demonstrator detector with in-built charge sensitive CUBE preamplifiers and a Schottky e- collection CdTe Medipix3RX detector systems were investigated to understand the underlying mechanisms that limit spectroscopic, imaging performances and stability and to find ways to overcome or minimise those limitations. The energy resolution and stability of the Ge demonstrator detector was found to have the required characteristics for XAFS measurements. Charge sharing was identified as a limiting factor to the resolution which is going to be addressed in the future development of a full detector system as well as reductions in electronic noise and cross-talk effects. The stability study of the Schottky CdTe Medipix3RX detector showed that polarization is highly dependent on temperature, irradiation duration and incoming flux. A new pixel behaviour called tri-phase (3-P) pixel was identified and a novel method for determining optimum operational conditions was developed. The use of the 3-P pixels as a criterion for depolarization resulted in a stable performance of the detector. Furthermore, the detector was applied in powder diffraction measurement at the I15 beam line and resulted in the detector diffraction pattern matching the simulated data. CdTe Medipix3RX and HEXITEC spectroscopic imaging detectors were applied in identification and discrimination of transitional metals for security application and K-edge subtraction for medical applications. The results showed that both detectors have potential

  14. Quantitative mapping of total choline in healthy human breast using proton echo planar spectroscopic imaging (PEPSI) at 3 Tesla.

    Zhao, Chenguang; Bolan, Patrick J; Royce, Melanie; Lakkadi, Navneeth; Eberhardt, Steven; Sillerud, Laurel; Lee, Sang-Joon; Posse, Stefan

    2012-11-01

    To quantitatively measure tCho levels in healthy breasts using Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI). The two-dimensional mapping of tCho at 3 Tesla across an entire breast slice using PEPSI and a hybrid spectral quantification method based on LCModel fitting and integration of tCho using the fitted spectrum were developed. This method was validated in 19 healthy females and compared with single voxel spectroscopy (SVS) and with PRESS prelocalized conventional Magnetic Resonance Spectroscopic Imaging (MRSI) using identical voxel size (8 cc) and similar scan times (∼7 min). A tCho peak with a signal to noise ratio larger than 2 was detected in 10 subjects using both PEPSI and SVS. The average tCho concentration in these subjects was 0.45 ± 0.2 mmol/kg using PEPSI and 0.48 ± 0.3 mmol/kg using SVS. Comparable results were obtained in two subjects using conventional MRSI. High lipid content in the spectra of nine tCho negative subjects was associated with spectral line broadening of more than 26 Hz, which made tCho detection impossible. Conventional MRSI with PRESS prelocalization in glandular tissue in two of these subjects yielded tCho concentrations comparable to PEPSI. The detection sensitivity of PEPSI is comparable to SVS and conventional PRESS-MRSI. PEPSI can be potentially used in the evaluation of tCho in breast cancer. A tCho threshold concentration value of ∼0.7 mmol/kg might be used to differentiate between cancerous and healthy (or benign) breast tissues based on this work and previous studies. Copyright © 2012 Wiley Periodicals, Inc.

  15. The SOLAR-C Mission: Science Objectives and Current Status

    Suematsu, Y.; Solar-C Working Group

    2016-04-01

    The SOLAR-C is a Japan-led international solar mission for mid-2020s designed to investigate the magnetic activities of the Sun, focusing on the study in heating and dynamical phenomena of the chromosphere and corona, and to advance algorithms for predicting short and long term solar magnetic activities. For these purposes, SOLAR-C will carry three dedicated instruments; the Solar UV-Vis-IR Telescope (SUVIT), the EUV Spectroscopic Telescope (EUVST) and the High Resolution Coronal Imager (HCI), to jointly observe the entire visible solar atmosphere with essentially the same high spatial resolution (0.1"-0.3"), performing high resolution spectroscopic measurements over all atmospheric regions and spectro-polarimetric measurements from the photosphere through the upper chromosphere. SOLAR-C will also contribute to understand the solar influence on the Sun-Earth environments with synergetic wide-field observations from ground-based and other space missions.

  16. Initial results of 3-dimensional 1H-magnetic resonance spectroscopic imaging in the localization of prostate cancer at 3 Tesla: should we use an endorectal coil?

    Yakar, D.; Heijmink, S.W.T.P.J.; Hulsbergen-van de Kaa, C.A.; Huisman, H.J.; Barentsz, J.O.; Futterer, J.J.; Scheenen, T.W.J.

    2011-01-01

    PURPOSE: The purpose of this study was to compare the diagnostic performance of 3 Tesla, 3-dimensional (3D) magnetic resonance spectroscopic imaging (MRSI) in the localization of prostate cancer (PCa) with and without the use of an endorectal coil (ERC). MATERIALS AND METHODS: Our prospective study

  17. A polymer-based magnetic resonance tracer for visualization of solid tumors by 13C spectroscopic imaging.

    Yoshikazu Suzuki

    Full Text Available Morphological imaging precedes lesion-specific visualization in magnetic resonance imaging (MRI because of the superior ability of this technique to depict tissue morphology with excellent spatial and temporal resolutions. To achieve lesion-specific visualization of tumors by MRI, we investigated the availability of a novel polymer-based tracer. Although the 13C nucleus is a candidate for a detection nucleus because of its low background signal in the body, the low magnetic resonance sensitivity of the nucleus needs to be resolved before developing a 13C-based tracer. In order to overcome this problem, we enriched polyethylene glycol (PEG, a biocompatible polymer, with 13C atoms. 13C-PEG40,000 (13C-PEG with an average molecular weight of 40 kDa emitted a single 13C signal with a high signal-to-noise ratio due to its ability to maintain signal sharpness, as was confirmed by in vivo investigation, and displayed a chemical shift sufficiently distinct from that of endogenous fat. 13C-PEG40,000 intravenously injected into mice showed long retention in circulation, leading to its effective accumulation in tumors reflecting the well-known phenomenon that macromolecules accumulate in tumors because of leaky tumor capillaries. These properties of 13C-PEG40,000 allowed visualization of tumors in mice by 13C spectroscopic imaging. These findings suggest that a technique based on 13C-PEG is a promising strategy for tumor detection.

  18. SDSS-III: Massive Spectroscopic Surveys of the Distant Universe, the Milky Way Galaxy, and Extra-Solar Planetary Systems

    Eisenstein, Daniel J.; Weinberg, David H.; Agol, Eric; Aihara, Hiroaki; Prieto, Carlos Allende; Anderson, Scott F.; Arns, James A.; Aubourg, Eric; Bailey, Stephen; Balbinot, Eduardo; Barkhouser, Robert

    2011-01-01

    Building on the legacy of the Sloan Digital Sky Survey (SDSS-I and II), SDSS-III is a program of four spectroscopic surveys on three scientific themes: dark energy and cosmological parameters, the history and structure of the Milky Way, and the population of giant planets around other stars. The Baryon Oscillation Spectroscopic Survey (BOSS) will measure redshifts of 1.5 million massive galaxies and Lyα forest spectra of 150,000 quasars, using the baryon acoustic oscillation (BAO) feature of large scale structure to obtain percent-level determinations of the distance scale and Hubble expansion rate at z 5 evolved, late-type stars, measuring separate abundances for ∼ 15 elements per star and creating the first high-precision spectroscopic survey of all Galactic stellar populations (bulge, bar, disks, halo) with a uniform set of stellar tracers and spectral diagnostics. The Multi-object APO Radial Velocity Large-area Survey (MARVELS) will monitor radial velocities of more than 8000 FGK stars with the sensitivity and cadence (10-40 m s -1 , ∼ 24 visits per star) needed to detect giant planets with periods up to two years, providing an unprecedented data set for understanding the formation and dynamical evolution of giant planet systems. As of January 2011, SDSS-III has obtained spectra of more than 240,000 galaxies, 29,000 z (ge) 2.2 quasars, and 140,000 stars, including 74,000 velocity measurements of 2580 stars for MARVELS. In keeping with SDSS tradition, SDSS-III will provide regular public releases of all its data, beginning with SDSS Data Release 8 (DR8) in January 2011.

  19. Lateralisation with magnetic resonance spectroscopic imaging in temporal lobe epilepsy: an evaluation of visual and region-of-interest analysis of metabolite concentration images

    Vikhoff-Baaz, B. [Sahlgrenska University Hospital, Goeteborg (Sweden); Div. of Medical Physics and Biomedical Engineering, Goeteborg Univ. (Sweden); Goeteborg Univ. (Sweden). Dept. of Radiation Physics; Malmgren, K. [Dept. of Neurology, Goeteborg Univ. (Sweden); Joensson, L.; Ekholm, S. [Dept. of Radiology, Goeteborg Univ. (Sweden); Starck, G. [Div. of Medical Physics and Biomedical Engineering, Goeteborg Univ. (Sweden); Ljungberg, M.; Forssell-Aronsson, E. [Goeteborg Univ. (Sweden). Dept. of Radiation Physics; Uvebrant, P. [Dept. of Paediatrics, Goeteborg Univ. (Sweden)

    2001-09-01

    We carried out spectroscopic imaging (MRSI) on nine consecutive patients with temporal lobe epilepsy being assessed for epilepsy surgery, and nine neurologically healthy, age-matched volunteers. A volume of interest (VOI) was angled along the temporal horns on axial and sagittal images, and symmetrically over the temporal lobes on coronal images. Images showing the concentrations of N-acetylaspartate (NAA) and of choline-containing compounds plus creatine and phosphocreatine (Cho + Cr) were used for lateralisation. We compared assessment by visual inspection and by signal analysis from regions of interest (ROI) in different positions, where side-to-side differences in NAA/(Cho + Cr) ratio were used for lateralisation. The NAA/(Cho + Cr) ratio from the different ROI was also compared with that in the brain stem to assess if the latter could be used as an internal reference, e. g., for identification of bilateral changes. The metabolite concentration images were found useful for lateralisation of temporal lobe abnormalities related to epilepsy. Visual analysis can, with high accuracy, be used routinely. ROI analysis is useful for quantifying changes, giving more quantitative information about spatial distribution and the degree of signal loss. There was a large variation in NAA/(Cho + Cr) values in both patients and volunteers. The brain stem may be used as a reference for identification of bilateral changes. (orig.)

  20. Lateralisation with magnetic resonance spectroscopic imaging in temporal lobe epilepsy: an evaluation of visual and region-of-interest analysis of metabolite concentration images

    Vikhoff-Baaz, B.; Joensson, L.; Ekholm, S.; Starck, G.

    2001-01-01

    We carried out spectroscopic imaging (MRSI) on nine consecutive patients with temporal lobe epilepsy being assessed for epilepsy surgery, and nine neurologically healthy, age-matched volunteers. A volume of interest (VOI) was angled along the temporal horns on axial and sagittal images, and symmetrically over the temporal lobes on coronal images. Images showing the concentrations of N-acetylaspartate (NAA) and of choline-containing compounds plus creatine and phosphocreatine (Cho + Cr) were used for lateralisation. We compared assessment by visual inspection and by signal analysis from regions of interest (ROI) in different positions, where side-to-side differences in NAA/(Cho + Cr) ratio were used for lateralisation. The NAA/(Cho + Cr) ratio from the different ROI was also compared with that in the brain stem to assess if the latter could be used as an internal reference, e. g., for identification of bilateral changes. The metabolite concentration images were found useful for lateralisation of temporal lobe abnormalities related to epilepsy. Visual analysis can, with high accuracy, be used routinely. ROI analysis is useful for quantifying changes, giving more quantitative information about spatial distribution and the degree of signal loss. There was a large variation in NAA/(Cho + Cr) values in both patients and volunteers. The brain stem may be used as a reference for identification of bilateral changes. (orig.)

  1. Using Raman spectroscopic imaging for non-destructive analysis of filler distribution in chalk filled polypropylene

    Boros, Evelin; Porse, Peter Bak; Nielsen, Inga

    2016-01-01

    A feasibility study on using Raman spectral imaging for visualization and analysis of filler distribution in chalk filled poly-propylene samples has been carried out. The spectral images were acquired using a Raman spectrometer with 785 nm light source.Eight injection-molded samples with concentr...

  2. Role of endorectal MR imaging and MR spectroscopic imaging in defining treatable intraprostatic tumor foci in prostate cancer: Quantitative analysis of imaging contour compared to whole-mount histopathology

    Anwar, Mekhail; Westphalen, Antonio C.; Jung, Adam J.; Noworolski, Susan M.; Simko, Jeffry P.; Kurhanewicz, John; Roach, Mack; Carroll, Peter R.; Coakley, Fergus V.

    2014-01-01

    Purpose: To investigate the role of endorectal MR imaging and MR spectroscopic imaging in defining the contour of treatable intraprostatic tumor foci in prostate cancer, since targeted therapy requires accurate target volume definition. Materials and methods: We retrospectively identified 20 patients with prostate cancer who underwent endorectal MR imaging and MR spectroscopic imaging prior to radical prostatectomy and subsequent creation of detailed histopathological tumor maps from whole-mount step sections. Two experienced radiologists independently reviewed all MR images and electronically contoured all suspected treatable (⩾0.5 cm 3 ) tumor foci. Deformable co-registration in MATLAB was used to calculate the margin of error between imaging and histopathological contours at both capsular and non-capsular surfaces and the treatment margin required to ensure at least 95% tumor coverage. Results: Histopathology showed 17 treatable tumor foci in 16 patients, of which 8 were correctly identified by both readers and an additional 2 were correctly identified by reader 2. For all correctly identified lesions, both readers accurately identified that tumor contacted the prostatic capsule, with no error in contour identification. On the non-capsular border, the median distance between the imaging and histopathological contour was 1.4 mm (range, 0–12). Expanding the contour by 5 mm at the non-capsular margin included 95% of tumor volume not initially covered within the MR contour. Conclusions: Endorectal MR imaging and MR spectroscopic imaging can be used to accurately contour treatable intraprostatic tumor foci; adequate tumor coverage is achieved by expanding the treatment contour at the non-capsular margin by 5 mm

  3. A NOISE ADAPTIVE FUZZY EQUALIZATION METHOD FOR PROCESSING SOLAR EXTREME ULTRAVIOLET IMAGES

    Druckmueller, M., E-mail: druckmuller@fme.vutbr.cz [Institute of Mathematics, Faculty of Mechanical Engineering, Brno University of Technology, Technicka 2, 616 69 Brno (Czech Republic)

    2013-08-15

    A new image enhancement tool ideally suited for the visualization of fine structures in extreme ultraviolet images of the corona is presented in this paper. The Noise Adaptive Fuzzy Equalization method is particularly suited for the exceptionally high dynamic range images from the Atmospheric Imaging Assembly instrument on the Solar Dynamics Observatory. This method produces artifact-free images and gives significantly better results than methods based on convolution or Fourier transform which are often used for that purpose.

  4. Micro-Spectroscopic Chemical Imaging of Individual Identified Marine Biogenic and Ambient Organic Ice Nuclei (Invited)

    Knopf, D. A.; Alpert, P. A.; Wang, B.; OBrien, R. E.; Moffet, R. C.; Aller, J. Y.; Laskin, A.; Gilles, M.

    2013-12-01

    Atmospheric ice formation represents one of the least understood atmospheric processes with important implications for the hydrological cycle and climate. Current freezing descriptions assume that ice active sites on the particle surface initiate ice nucleation, however, the nature of these sites remains elusive. Here, we present a new experimental method that allows us to relate physical and chemical properties of individual particles with observed water uptake and ice nucleation ability using a combination of micro-spectroscopic and optical single particle analytical techniques. We apply this method to field-collected particles and particles generated via bursting of bubbles produced by glass frit aeration and plunging water impingement jets in a mesocosm containing artificial sea water and bacteria and/or phytoplankton. The most efficient ice nuclei (IN) within a particle population are identified and characterized. Single particle characterization is achieved by computer controlled scanning electron microscopy with energy dispersive analysis of X-rays (CCSEM/EDX) and scanning transmission X-ray microscopy with near edge X-ray absorption fine structure spectroscopy. A vapor controlled cooling-stage coupled to an optical microscope is used to determine the onsets of water uptake, immersion freezing, and deposition ice nucleation of the individual particles as a function of temperature (T) as low as 200 K and relative humidity (RH) up to water saturation. In addition, we perform CCSEM/EDX to obtain on a single particle level the elemental composition of the entire particle population. Thus, we can determine if the IN are exceptional in nature or belong to a major particle type class with respect to composition and size. We find that ambient and sea spray particles are coated by organic material and can induce ice formation under tropospheric relevant conditions. Micro-spectroscopic single particle analysis of the investigated particle samples invokes a potential

  5. Spectroscopic imaging of self-organization in high power impulse magnetron sputtering plasmas

    Andersson, Joakim; Ni, Pavel; Anders, André

    2013-01-01

    Excitation and ionization conditions in traveling ionization zones of high power impulse magnetron sputtering plasmas were investigated using fast camera imaging through interference filters. The images, taken in end-on and side-on views using light of selected gas and target atom and ion spectral lines, suggest that ionization zones are regions of enhanced densities of electrons, and excited atoms and ions. Excited atoms and ions of the target material (Al) are strongly concentrated near the target surface. Images from the highest excitation energies exhibit the most localized regions, suggesting localized Ohmic heating consistent with double layer formation

  6. Preliminary results from a high-pressure imaging spectroscopic proportional counter

    Hall, C.J.; Bazzano, A.; Lewis, R.A.; Parker, B.; Ubertini, P.; Worgan, J.S.

    1992-01-01

    A new type of high-pressure proportional counter, with both spatial resolution and spectroscopic capabilities is being jointly developed by the Istituto di Astrofisica Spaziale (CNR), Frascati, Italy and the SERC Daresbury Laboratory, Warrington, UK. The characteristics of the detector can be optimized for the particular requirement of the experiment, either for x-ray astronomy observations from space, or for the high count rate applications associated with a synchrotron light source. In its baseline configuration, the detector is filled to 5 bar with a xenon/quench gas mixture and will be sensitive over the energy range 5 keV to 150 keV (2.5 to 0.08 A). The positional resolution will range from 500 μm at the lower energies to around 1 mm at the higher end of the energy range. The current prototype has a sensitive area of 200x200 mm. The final version is hoped to have an area closer to 425x425 mm. The very small photon absorption length in the higher pressure gas allows the parallax effect, a feature of 1 atmosphere detectors, to be greatly reduced. The timing resolution (150 ns) of the detector enables both a high-rate capability and the possibility of the escape gate technique to achieve higher spectral resolution at energies > the Xe K edge. Preliminary results are presented showing the spectral and positional resolution for the prototype detector

  7. A deep X-ray spectroscopic survey of the ESO imaging survey fields

    Nørgaard-Nielsen, Hans Ulrik; Jørgensen, H.E.; Hansen, Lene

    1998-01-01

    The deepest ROSAT surveys have shown, that, in the energy range 0.5-2.0 keV, QSO's can account for similar to 30 per cent of the Diffuse X-ray Background (DXRB), and Narrow Emission Line Galaxies (NELG) and clusters of galaxies for about 10 per cent each. But, by assuming characteristic spectral ...... provide new insight into the evolution of galaxies, clusters of galaxies and AGN's.......The deepest ROSAT surveys have shown, that, in the energy range 0.5-2.0 keV, QSO's can account for similar to 30 per cent of the Diffuse X-ray Background (DXRB), and Narrow Emission Line Galaxies (NELG) and clusters of galaxies for about 10 per cent each. But, by assuming characteristic spectral....... This spectroscopic X-ray survey will provide a large, statistically complete, sample of sources detected at high energies, more than an order of magnitude fainter than obtained by previous missions. The study of these sources will significantly improve our understanding not only of the origin of DXRB, but also...

  8. A spectroscopic study on the effect of ultra-violet solar radiation in Antarctica on the human skin fibroblast cells

    Tatsuyuki Yamamoto

    2013-11-01

    Full Text Available A study on the effect of the solar ultra-violet radiation on the human skin fibroblast cells revealed that the production of matrix metalloproteinase-2 was inhibited by the radiation. A CO2 incubator connected by optical fibers to a reflector telescope for collecting the solar light was built at Syowa station by the 49th Japanese Antarctica Research Expedition. The direction of the telescope was continuously controlled by a sun-tracker to follow the movement of the Sun automatically. The intensity of the collected light was monitored by a portable spectrophotometer housed inside. The human skin fibroblast cells were incubated in the CO2 chamber to investigate the effect of the solar radiation at Syowa station and were compared with those reference experiments at a laboratory in Japan. The results showed cell damage by strong UV radiation. The production of matrix metalloproteinase-2 was prompted by the moderate UV-B, but was inhibited by the strong UV-B radiation, as studied under laboratory conditions in Japan. The effect of strong solar radiation at Syowa station involving the radiation of UV-B region was estimated to be of the same extent of the radiation caused by an artificial UV-B light with the intensity more than 50 mJ/cm2.

  9. Mission Concepts for High-Resolution Solar Imaging with a Photon Sieve

    Rabin, Douglas M.; Davila, Joseph; Daw, Adrian N.; Denis, Kevin L.; Novo-Gradac, Anne-Marie; Shah, Neerav; Widmyer, Thomas R.

    2017-08-01

    The best EUV coronal imagers are unable to probe the expected energy dissipation scales of the solar corona (rocket, a single spacecraft with a deployed boom, and two spacecraft flying in precise formation.

  10. High resolution spectroscopic mapping imaging applied in situ to multilayer structures for stratigraphic identification of painted art objects

    Karagiannis, Georgios Th.

    2016-04-01

    The development of non-destructive techniques is a reality in the field of conservation science. These techniques are usually not so accurate, as the analytical micro-sampling techniques, however, the proper development of soft-computing techniques can improve their accuracy. In this work, we propose a real-time fast acquisition spectroscopic mapping imaging system that operates from the ultraviolet to mid infrared (UV/Vis/nIR/mIR) area of the electromagnetic spectrum and it is supported by a set of soft-computing methods to identify the materials that exist in a stratigraphic structure of paint layers. Particularly, the system acquires spectra in diffuse-reflectance mode, scanning in a Region-Of-Interest (ROI), and having wavelength range from 200 up to 5000 nm. Also, a fuzzy c-means clustering algorithm, i.e., the particular soft-computing algorithm, produces the mapping images. The evaluation of the method was tested on a byzantine painted icon.

  11. Fast mapping of the T2 relaxation time of cerebral metabolites using proton echo-planar spectroscopic imaging (PEPSI).

    Tsai, Shang-Yueh; Posse, Stefan; Lin, Yi-Ru; Ko, Cheng-Wen; Otazo, Ricardo; Chung, Hsiao-Wen; Lin, Fa-Hsuan

    2007-05-01

    Metabolite T2 is necessary for accurate quantification of the absolute concentration of metabolites using long-echo-time (TE) acquisition schemes. However, lengthy data acquisition times pose a major challenge to mapping metabolite T2. In this study we used proton echo-planar spectroscopic imaging (PEPSI) at 3T to obtain fast T2 maps of three major cerebral metabolites: N-acetyl-aspartate (NAA), creatine (Cre), and choline (Cho). We showed that PEPSI spectra matched T2 values obtained using single-voxel spectroscopy (SVS). Data acquisition for 2D metabolite maps with a voxel volume of 0.95 ml (32 x 32 image matrix) can be completed in 25 min using five TEs and eight averages. A sufficient spectral signal-to-noise ratio (SNR) for T2 estimation was validated by high Pearson's correlation coefficients between logarithmic MR signals and TEs (R2 = 0.98, 0.97, and 0.95 for NAA, Cre, and Cho, respectively). In agreement with previous studies, we found that the T2 values of NAA, but not Cre and Cho, were significantly different between gray matter (GM) and white matter (WM; P PEPSI and SVS scans was less than 9%. Consistent spatial distributions of T2 were found in six healthy subjects, and disagreement among subjects was less than 10%. In summary, the PEPSI technique is a robust method to obtain fast mapping of metabolite T2. (c) 2007 Wiley-Liss, Inc.

  12. Dynamic Nuclear Polarization at low temperature and high magnetic eld for biomedical applications in Magnetic Resonance Spectroscopic Imaging

    Goutailler, Florent

    2011-01-01

    The aim of this thesis work was to design, build and optimize a large volume multi-samples DNP (Dynamic Nuclear Polarization) polarizer dedicated to Magnetic Resonance Spectroscopic Imaging applications. The experimental system is made up of a high magnetic field magnet (3,35 T) in which takes place a cryogenic system with a pumped bath of liquid helium ("4He) allowing temperatures lower than 1,2 K. A set of inserts is used for the different steps of DNP: irradiation of the sample by a microwave field (f=94 GHz and P=50 mW), polarization measurement by Nuclear Magnetic Resonance... With this system, up to three samples of 1 mL volume can be polarized to a rate of few per-cents. The system has a long autonomy of four hours, so it can be used for polarizing molecules with a long time constant of polarization. Finally, the possibility to get quasi-simultaneously, after dissolution, several samples with a high rate of polarization opens the way of new applications in biomedical imaging. (author) [fr

  13. NEAR-INFRARED IMAGING AND SPECTROSCOPIC SURVEY OF THE SOUTHERN REGION OF THE YOUNG OPEN CLUSTER NGC 2264

    Marinas, Naibi; Lada, Elizabeth A. [Astronomy Department, University of Florida, Gainesville, FL 32611 (United States); Teixiera, Paula S. [Department of Astrophysics, University of Vienna, Tuerkenschanzstrasse 17, A-1180 Vienna (Austria); Lada, Charles J. [Harvard-Smithsonian CFA, Cambridge, MA (United States)

    2013-08-01

    We have obtained JHK near-IR images and JH band low-resolution spectra of candidate members of the southern region of the young open cluster NGC 2264. We have determined spectral types from H-band spectra for 54 sources, 25 of which are classified for the first time. The stars in our sample cover a large range of spectral types (A8-M8). Using a cluster distance of 780 pc, we determined a median age of 1 Myr for this region of NGC 2264, with 90% of the stars being 5 Myr or younger. To improve the statistical significance of our sample, we included 66 additional cluster members within our field of view with optical spectral classification in the literature. We derived infrared excesses using stellar properties to model the photospheric emission for each source and the extinction to correct FLAMINGOS near-IR and Spitzer mid-IR photometry, and obtained a disk fraction of 51% {+-} 5% for the region. Binning the stars by stellar mass, we find a disk fraction of 38% {+-} 9% for the 0.1-0.3 solar mass group, 55% {+-} 6% for 0.3-1 solar masses, and 58% {+-} 10% for the higher than 1 solar mass group. The lower disk fraction for the lower mass stars is similar to the results found in non-cluster regions like Taurus and Chamaeleon, but differs from the older 3 Myr cluster IC 348 in which the disk fraction is lower for the higher mass stars. This mass-dependent disk fraction is accentuated in the sample with isochrone ages younger than 2 Myr. Here, we find that 45% {+-} 11% of the 0.1-0.3 solar mass stars have disks, 60% {+-} 7% of the 0.3-1 solar mass stars have disks, and all 1-3 solar mass stars have disks. Stellar masses might be an important factor in the ability of a system to form or retain a disk early on. However, regardless of the stellar mass, the large infrared excesses expected from optically thick disks disappear within the first 2 Myr for all stars in our study and small excesses from optically thin disks are found mostly in sources younger than 4 Myr.

  14. Quality control of roll-to-roll processed polymer solar modules by complementary imaging methods

    Rösch, R.; Krebs, Frederik C; Tanenbaum, D.M.

    2012-01-01

    We applied complementary imaging methods to investigate processing failures of roll-to-roll solution processed polymer solar modules based on polymer:fullerene bulk heterojunctions. For investigation of processing deficiencies in solar modules we employed dark lock-in thermography (DLIT......), electroluminescence (ELI) and photoluminescence/reflection imaging (PLI/RI) complemented by optical imaging (OI). The combination of all high resolution images allowed us to allocate the origin of processing errors to a specific deposition process, i.e. the insufficient coverage of an electrode interlayer...

  15. Spatially Resolved Images and Solar Irradiance Variability R ...

    Abstract. The Sun is the primary source of energy that governs both the terrestrial climate and near-earth space environment. Variations in UV irradiances seen at earth are the sum of global (solar dynamo) to regional. (active region, plage, network, bright points and background) solar mag- netic activities that can be ...

  16. The use of a sky camera for solar radiation estimation based on digital image processing

    Alonso-Montesinos, J.; Batlles, F.J.

    2015-01-01

    The necessary search for a more sustainable global future means using renewable energy sources to generate pollutant-free electricity. CSP (Concentrated solar power) and PV (photovoltaic) plants are the systems most in demand for electricity production using solar radiation as the energy source. The main factors affecting final electricity generation in these plants are, among others, atmospheric conditions; therefore, knowing whether there will be any change in the solar radiation hitting the plant's solar field is of fundamental importance to CSP and PV plant operators in adapting the plant's operation mode to these fluctuations. Consequently, the most useful technology must involve the study of atmospheric conditions. This is the case for sky cameras, an emerging technology that allows one to gather sky information with optimal spatial and temporal resolution. Hence, in this work, a solar radiation estimation using sky camera images is presented for all sky conditions, where beam, diffuse and global solar radiation components are estimated in real-time as a novel way to evaluate the solar resource from a terrestrial viewpoint. - Highlights: • Using a sky camera, the solar resource has been estimated for one minute periods. • The sky images have been processed to estimate the solar radiation at pixel level. • The three radiation components have been estimated under all sky conditions. • Results have been presented for cloudless, partially-cloudy and overcast conditions. • For beam and global radiation, the nRMSE value is of about 11% under overcast skies.

  17. Short- and long-term quantitation reproducibility of brain metabolites in the medial wall using proton echo planar spectroscopic imaging.

    Tsai, Shang-Yueh; Lin, Yi-Ru; Wang, Woan-Chyi; Niddam, David M

    2012-11-15

    Proton echo planar spectroscopic imaging (PEPSI) is a fast magnetic resonance spectroscopic imaging (MRSI) technique that allows mapping spatial metabolite distributions in the brain. Although the medial wall of the cortex is involved in a wide range of pathological conditions, previous MRSI studies have not focused on this region. To decide the magnitude of metabolic changes to be considered significant in this region, the reproducibility of the method needs to be established. The study aims were to establish the short- and long-term reproducibility of metabolites in the right medial wall and to compare regional differences using a constant short-echo time (TE30) and TE averaging (TEavg) optimized to yield glutamatergic information. 2D sagittal PEPSI was implemented at 3T using a 32 channel head coil. Acquisitions were repeated immediately and after approximately 2 weeks to assess the coefficients of variation (COV). COVs were obtained from eight regions-of-interest (ROIs) of varying size and location. TE30 resulted in better spectral quality and similar or lower quantitation uncertainty for all metabolites except glutamate (Glu). When Glu and glutamine (Gln) were quantified together (Glx) reduced quantitation uncertainty and increased reproducibility was observed for TE30. TEavg resulted in lowered quantitation uncertainty for Glu but in less reliable quantification of several other metabolites. TEavg did not result in a systematically improved short- or long-term reproducibility for Glu. The ROI volume was a major factor influencing reproducibility. For both short- and long-term repetitions, the Glu COVs obtained with TEavg were 5-8% for the large ROIs, 12-17% for the medium sized ROIs and 16-26% for the smaller cingulate ROIs. COVs obtained with TE30 for the less specific Glx were 3-5%, 8-10% and 10-15%. COVs for N-acetyl aspartate, creatine and choline using TE30 with long-term repetition were between 2-10%. Our results show that the cost of more specific

  18. Magnetic resonance spectroscopic imaging in breast cancer detection: possibilities beyond the conventional theoretical framework for data analysis

    Belkic, Karen E-mail: karen.belkic@radfys.ki.se

    2004-06-01

    Magnetic Resonance Spectroscopic Imaging (MRSI) is a promising method for breast cancer diagnosis, providing, in addition to the anatomic picture, complementary biochemical and physiologic information in the form of spectra. It should be able to identify key biochemical changes before the tumour becomes detectable by other functional imaging methods that rely upon single markers not entirely sensitive or specific for malignant activity. MRSI is potentially well suited for screening and repeated monitoring since it entails no radiation exposure. There are, however, limitations to current applications of Magnetic Resonance Spectroscopy (MRS) and MRSI. Many of these can be directly related to reliance upon the conventional data analytical method, i.e. the Fast Fourier Transform (FFT), which has low resolution, poor signal/noise (S/N) in clinical signals, supplies only shape spectra and requires fitting, which is non-unique, so that the number of metabolites must be guessed in advance. This can lead to spurious peaks (over-fitting) and true metabolites being undetected (under-fitting). These limitations of the FFT can be circumvented by recent mathematical advances in signal processing via e.g. the Fast Pade Transform (FPT). As a high resolution, non-linear, stable parametric method, the FPT substantially improves S/N, and fulfills stringent requirements for tumour diagnostics: no post-processing fitting, provides precise numerical results for all peak parameters, and specifies the exact number of metabolites (including those that overlap) from the encoded data. We illustrate in a realistic synthesized model problem similar to MRS that the FPT can identify overlapping peaks that are entirely missed by the FFT, and we give an example from in vivo MRS of the superior resolving power of the FPT compared to FFT at short acquisition time. We also perform detailed paired and logistic regression analyses of Nuclear Magnetic Resonance (NMR) data on extracted breast specimens

  19. Accelerated echo-planar J-resolved spectroscopic imaging in the human brain using compressed sensing: a pilot validation in obstructive sleep apnea.

    Sarma, M K; Nagarajan, R; Macey, P M; Kumar, R; Villablanca, J P; Furuyama, J; Thomas, M A

    2014-06-01

    Echo-planar J-resolved spectroscopic imaging is a fast spectroscopic technique to record the biochemical information in multiple regions of the brain, but for clinical applications, time is still a constraint. Investigations of neural injury in obstructive sleep apnea have revealed structural changes in the brain, but determining the neurochemical changes requires more detailed measurements across multiple brain regions, demonstrating a need for faster echo-planar J-resolved spectroscopic imaging. Hence, we have extended the compressed sensing reconstruction of prospectively undersampled 4D echo-planar J-resolved spectroscopic imaging to investigate metabolic changes in multiple brain locations of patients with obstructive sleep apnea and healthy controls. Nonuniform undersampling was imposed along 1 spatial and 1 spectral dimension of 4D echo-planar J-resolved spectroscopic imaging, and test-retest reliability of the compressed sensing reconstruction of the nonuniform undersampling data was tested by using a brain phantom. In addition, 9 patients with obstructive sleep apnea and 11 healthy controls were investigated by using a 3T MR imaging/MR spectroscopy scanner. Significantly reduced metabolite differences were observed between patients with obstructive sleep apnea and healthy controls in multiple brain regions: NAA/Cr in the left hippocampus; total Cho/Cr and Glx/Cr in the right hippocampus; total NAA/Cr, taurine/Cr, scyllo-Inositol/Cr, phosphocholine/Cr, and total Cho/Cr in the occipital gray matter; total NAA/Cr and NAA/Cr in the medial frontal white matter; and taurine/Cr and total Cho/Cr in the left frontal white matter regions. The 4D echo-planar J-resolved spectroscopic imaging technique using the nonuniform undersampling-based acquisition and compressed sensing reconstruction in patients with obstructive sleep apnea and healthy brain is feasible in a clinically suitable time. In addition to brain metabolite changes previously reported by 1D MR

  20. A portable neutron spectroscope (NSPECT) for detection, imaging and identification of nuclear material

    Ryan, James M.; Bancroft, Christopher; Bloser, Peter; Bravar, Ulisse; Fourguette, Dominique; Frost, Colin; Larocque, Liane; McConnell, Mark L.; Legere, Jason; Pavlich, Jane; Ritter, Greg; Wassick, Greg; Wood, Joshua; Woolf, Richard

    2010-08-01

    We have developed, fabricated and tested a prototype imaging neutron spectrometer designed for real-time neutron source location and identification. Real-time detection and identification is important for locating materials. These materials, specifically uranium and transuranics, emit neutrons via spontaneous or induced fission. Unlike other forms of radiation (e.g. gamma rays), penetrating neutron emission is very uncommon. The instrument detects these neutrons, constructs images of the emission pattern, and reports the neutron spectrum. The device will be useful for security and proliferation deterrence, as well as for nuclear waste characterization and monitoring. The instrument is optimized for imaging and spectroscopy in the 1-20 MeV range. The detection principle is based upon multiple elastic neutron-proton scatters in organic scintillator. Two detector panel layers are utilized. By measuring the recoil proton and scattered neutron locations and energies, the direction and energy spectrum of the incident neutrons can be determined and discrete and extended sources identified. Event reconstruction yields an image of the source and its location. The hardware is low power, low mass, and rugged. Its modular design allows the user to combine multiple units for increased sensitivity. We will report the results of laboratory testing of the instrument, including exposure to a calibrated Cf-252 source. Instrument parameters include energy and angular resolution, gamma rejection, minimum source identification distances and times, and projected effective area for a fully populated instrument.

  1. Magnetic Resonance Spectroscopic Imaging of Tumor Metabolic Markers for Cancer Diagnosis, Metabolic Phenotyping, and Characterization of Tumor Microenvironment

    Qiuhong He

    2004-01-01

    Full Text Available Cancer cells display heterogeneous genetic characteristics, depending on the tumor dynamic microenvironment. Abnormal tumor vasculature and poor tissue oxygenation generate a fraction of hypoxic tumor cells that have selective advantages in metastasis and invasion and often resist chemo- and radiation therapies. The genetic alterations acquired by tumors modify their biochemical pathways, which results in abnormal tumor metabolism. An elevation in glycolysis known as the “Warburg effect” and changes in lipid synthesis and oxidation occur. Magnetic resonance spectroscopy (MRS has been used to study tumor metabolism in preclinical animal models and in clinical research on human breast, brain, and prostate cancers. This technique can identify specific genetic and metabolic changes that occur in malignant tumors. Therefore, the metabolic markers, detectable by MRS, not only provide information on biochemical changes but also define different metabolic tumor phenotypes. When combined with the contrast-enhanced Magnetic Resonance Imaging (MRI, which has a high sensitivity for cancer diagnosis, in vivo magnetic resonance spectroscopic imaging (MRSI improves the diagnostic specificity of malignant human cancers and is becoming an important clinical tool for cancer management and care. This article reviews the MRSI techniques as molecular imaging methods to detect and quantify metabolic changes in various tumor tissue types, especially in extracranial tumor tissues that contain high concentrations of fat. MRI/MRSI methods have been used to characterize tumor microenvironments in terms of blood volume and vessel permeability. Measurements of tissue oxygenation and glycolytic rates by MRS also are described to illustrate the capability of the MR technology in probing molecular information non-invasively in tumor tissues and its important potential for studying molecular mechanisms of human cancers in physiological conditions.

  2. A Heuristic Approach to Remove the Background Intensity on White-light Solar Images. I. STEREO /HI-1 Heliospheric Images

    Stenborg, Guillermo; Howard, Russell A. [Space Science Division, U.S. Naval Research Laboratory, Washington, DC 20375 (United States)

    2017-04-10

    White-light coronal and heliospheric imagers observe scattering of photospheric light from both dust particles (the F-Corona) and free electrons in the corona (the K-corona). The separation of the two coronae is thus vitally important to reveal the faint K-coronal structures (e.g., streamers, co-rotating interaction regions, coronal mass ejections, etc.). However, the separation of the two coronae is very difficult, so we are content in defining a background corona that contains the F- and as little K- as possible. For both the LASCO-C2 and LASCO-C3 coronagraphs aboard the Solar and Heliospheric Observatory ( SOHO ) and the white-light imagers of the SECCHI suite aboard the Solar Terrestrial Relationships Observatory ( STEREO ), a time-dependent model of the background corona is generated from about a month of similar images. The creation of such models is possible because the missions carrying these instruments are orbiting the Sun at about 1 au. However, the orbit profiles for the upcoming Solar Orbiter and Solar Probe Plus missions are very different. These missions will have elliptic orbits with a rapidly changing radial distance, hence invalidating the techniques in use for the SOHO /LASCO and STEREO /SECCHI instruments. We have been investigating techniques to generate background models out of just single images that could be used for the Solar Orbiter Heliospheric Imager and the Wide-field Imager for the Solar Probe Plus packages on board the respective spacecraft. In this paper, we introduce a state-of-the-art, heuristic technique to create the background intensity models of STEREO /HI-1 data based solely on individual images, report on new results derived from its application, and discuss its relevance to instrumental and operational issues.

  3. Advanced Spectroscopic and Thermal Imaging Instrumentation for Shock Tube and Ballistic Range Facilities

    Grinstead, Jay H.; Wilder, Michael C.; Reda, Daniel C.; Cruden, Brett A.; Bogdanoff, David W.

    2010-01-01

    The Electric Arc Shock Tube (EAST) facility and Hypervelocity Free Flight Aerodynamic Facility (HFFAF, an aeroballistic range) at NASA Ames support basic research in aerothermodynamic phenomena of atmospheric entry, specifically shock layer radiation spectroscopy, convective and radiative heat transfer, and transition to turbulence. Innovative optical instrumentation has been developed and implemented to meet the challenges posed from obtaining such data in these impulse facilities. Spatially and spectrally resolved measurements of absolute radiance of a travelling shock wave in EAST are acquired using multiplexed, time-gated imaging spectrographs. Nearly complete spectral coverage from the vacuum ultraviolet to the near infrared is possible in a single experiment. Time-gated thermal imaging of ballistic range models in flight enables quantitative, global measurements of surface temperature. These images can be interpreted to determine convective heat transfer rates and reveal transition to turbulence due to isolated and distributed surface roughness at hypersonic velocities. The focus of this paper is a detailed description of the optical instrumentation currently in use in the EAST and HFFAF.

  4. Global Solar radiation in Spain from Satellite Images; Radiacion Solar Global en la Espana Peninsular a partir de images de satelite

    Ramirez Santigosa, L.; Mora Lopez, L.; Sidrach de Cardona Ortin, M.; Navarro Fernandez, A. A.; Varela conde, M.; Cruz Echeandia, M. de la

    2003-07-01

    In the context of the present work a series of algorithms of calculation of the solar radiation from satellite images has been developed. These models, have been applied to three years of images of the Meteosat satellite and the results of the treatment have been extrapolated to long term. For the development of the models of solar radiation registered in ground stations have been used, corresponding all of them to localities of peninsular Spain and the Balearic ones. The maximum periods of data available have been used, supposing in most of the cases periods of between 6 and 9 years. From the results has a year type of images of global solar radiation on horizontal surface. The original resolution of the image of 7x7 km in the study latitudes, has been revaluate to 5x5 km. This supposes to have a value of the typical radiation for every day of the year, each 5x5 km in the study territory. This information, supposes an important advance as far as the knowledge of the space distribution of the radiation solar,impossible to reach about alternative methods. Doubtlessly, the precision of the provided values is not comparable with pyranometric measures in a concrete localise, but it provides a very valid indicator in places in which, it not had previous information. In addition to the radiation maps, tables of the global solar radiation have been prepared on different inclinations, from the global radiation on horizontal surface calculated for every day of the year and in each pixel of the image. (Author) 24 refs.

  5. SPECTROSCOPIC OBSERVATIONS OF CONTINUOUS OUTFLOWS AND PROPAGATING WAVES FROM NOAA 10942 WITH EXTREME ULTRAVIOLET IMAGING SPECTROMETER/HINODE

    Nishizuka, N.; Hara, H.

    2011-01-01

    We focused on 'sit-and-stare' observations of an outflow region at the edge of active region NOAA 10942 on 2007 February 20 obtained by the Extreme ultraviolet Imaging Spectrometer on board Hinode. We analyzed the data above the base of the outflow and found both continuous outflows and waves, which propagate from the base of the outflow. The spectra at the base of the outflow and at higher locations show different properties. The line profiles show blue-side asymmetry at the base of the outflow where nonthermal broadening becomes large because of fast upflows generated by heating events. On the other hand, at higher locations line profiles are symmetric and the intensity disturbances vary in phase with the velocity disturbances. The correlations between the intensity and velocity disturbances become noticeable at higher locations, so this indicates evidence of (at least locally) upward propagating slow-mode waves along the outflow. We also found a transient oscillation of different period in the wavelet spectrum. This indicates that a different wave is additionally observed during a limited period. High cadence spectroscopic observations revealed intermittent signatures of nonthermal velocities. Each of them seems to correspond to the base of the propagating disturbances. Furthermore, a jet was captured by the sit-and-stare observations across the slit. The similarity of line profiles of the outflow and the jet may indicate that the flows and waves originate in unresolved explosive events in the lower atmosphere of the corona.

  6. {sup 1}H and {sup 31}P magnetic resonance spectroscopic imaging of white matter signal hyperintensity areas in elderly subjects

    Constans, J M [Department of Veterans Affairs Medical Center and University of California Magnetic Resonance Unit, San Francisco, CA (United States); [California Univ., San Francisco, CA (United States). Dept. of Radiology; Meyerhoff, D J [Department of Veterans Affairs Medical Center and University of California Magnetic Resonance Unit, San Francisco, CA (United States); [California Univ., San Francisco, CA (United States). Dept. of Radiology; Norman, D [California Univ., San Francisco, CA (United States). Dept. of Radiology; Fein, G [Department of Veterans Affairs Psychiatry Service, University of California, San Francisco, California (United States); [University of California, San Francisco, CA (United States). Dept. of Psychiatry; Weiner, M W [Department of Veterans Affairs Medical Center and University of California Magnetic Resonance Unit, San Francisco, CA (United States); [California Univ., San Francisco, CA (United States). Dept. of Radiology; [California Univ., San Francisco, CA (United States). Dept. of Medicine; [DVA Medical Center, Magnetic Resonance Spectroscopy Unit, San Francisco, CA (United States)

    1995-11-01

    White matter signal hyperintensities (WMSH) are commonly seen on MRI of elderly subjects. The purpose of this study was to characterize metabolic changes in the white matter of elderly subjects with extensive WMSH. We used water-suppressed proton ({sup 1}H) magnetic resonance spectroscopic imaging (MRSI) to compare six subjects with extensive WMSH with eight age-matched elderly subjects with minimal or absent WMSH, and phosphorus ({sup 31}P) MRSI to compare nine subjects with extensive WMSH and seven age-matched elderly subjects without extensive WMSH. Relative to region-matched tissue in elderly controls, extensive WMSH were associated with increased signal from choline-containing metabolites, no significant change of signal from N-acetylaspartate, and a trend to a decreased phosphomonoester (PME) resonance. These findings suggest that WMSH may be associated with an alteration of brain myelin phospholipids in the absence of axonal damage. There were no differences in energy phosphates, consistent with lack of ongoing brain ischemia. Within the group with extensive WMSH, PME resonance measures were significantly lower in WMSH than in contralateral normal-appearing white matter. These results provide information on pathophysiology of WMSH and a basis for comparison with WMSH in Alzheimer`s disease, vascular dementia, multiple sclerosis, and other diseases. (orig.). With 4 figs., 4 tabs.

  7. Noninvasive measurements of cardiac high-energy phosphate metabolites in dilated cardiomyopathy by using 31P spectroscopic chemical shift imaging

    Hansch, A.; Rzanny, R.; Heyne, J.-P.; Reichenbach, J.R.; Kaiser, W.A.; Leder, U.

    2005-01-01

    Dilated cardiomyopathy (DCM) is accompanied by an impaired cardiac energy metabolism. The aim of this study was to investigate metabolic ratios in patients with DCM compared to controls by using spectroscopic two-dimensional chemical shift imaging (2D-CSI). Twenty volunteers and 15 patients with severe symptoms (left ventricular ejection fraction, LVEF 30%) of DCM were investigated. Cardiac 31 P MR 2D-CSI measurements (voxel size: 40 x 40 x 100 mm 3 ) were performed with a 1.5 T whole-body scanner. Measurement time ranged from 15 min to 30 min. Peak areas and ratios of different metabolites were evaluated, including high-energy phosphates (PCr, ATP), 2,3-diphosphoglycerate (2,3-DPG) and phosphodiesters (PDE). In addition, we evaluated how PCr/ATP ratios correlate with LVEF as an established prognostic factor of heart failure. The PCr/γ-ATP ratio was significantly decreased in patients with moderate and severe DCM and showed a linear correlation with reduced LVEFs. PDE/ATP ratios were significantly increased only in patients with severe DCM as compared to volunteers. Applying 31 P MRS with commonly-available 2D-CSI sequences is a valuable technique to evaluate DCM by determining PCr/ATP ratios noninvasively. In addition to reduced PCr/ATP ratios observed in patients suffering from DCM, significantly-increased PDE/ATP ratios were found in patients with severe DCM. (orig.)

  8. A Solar Position Sensor Based on Image Vision.

    Ruelas, Adolfo; Velázquez, Nicolás; Villa-Angulo, Carlos; Acuña, Alexis; Rosales, Pedro; Suastegui, José

    2017-07-29

    Solar collector technologies operate with better performance when the Sun beam direction is normal to the capturing surface, and for that to happen despite the relative movement of the Sun, solar tracking systems are used, therefore, there are rules and standards that need minimum accuracy for these tracking systems to be used in solar collectors' evaluation. Obtaining accuracy is not an easy job, hence in this document the design, construction and characterization of a sensor based on a visual system that finds the relative azimuth error and height of the solar surface of interest, is presented. With these characteristics, the sensor can be used as a reference in control systems and their evaluation. The proposed sensor is based on a microcontroller with a real-time clock, inertial measurement sensors, geolocation and a vision sensor, that obtains the angle of incidence from the sunrays' direction as well as the tilt and sensor position. The sensor's characterization proved how a measurement of a focus error or a Sun position can be made, with an accuracy of 0.0426° and an uncertainty of 0.986%, which can be modified to reach an accuracy under 0.01°. The validation of this sensor was determined showing the focus error on one of the best commercial solar tracking systems, a Kipp & Zonen SOLYS 2. To conclude, the solar tracking sensor based on a vision system meets the Sun detection requirements and components that meet the accuracy conditions to be used in solar tracking systems and their evaluation or, as a tracking and orientation tool, on photovoltaic installations and solar collectors.

  9. Echo-Planar Imaging Based J-Resolved Spectroscopic Imaging for Improved Metabolite Detection in Prostate Cancer

    2012-10-01

    Clinical Setting" was presented at the 20th International Society of Magnetic Resonance in Medicine (ISMRM) meeting in Melbourne , Australia (May 5-11...experience. Eur Urol 2001;40(1):75–83. 5. Chandra RV, Heinze S, Dowling R, Shadbolt C, Costello A, Pedersen J. Endorectal mag- netic resonance imaging

  10. High-pulse energy supercontinuum laser for high-resolution spectroscopic photoacoustic imaging of lipids in the 1650-1850 nm region.

    Dasa, Manoj Kumar; Markos, Christos; Maria, Michael; Petersen, Christian R; Moselund, Peter M; Bang, Ole

    2018-04-01

    We propose a cost-effective high-pulse energy supercontinuum (SC) source based on a telecom range diode laser-based amplifier and a few meters of standard single-mode optical fiber, with a pulse energy density as high as ~25 nJ/nm in the 1650-1850 nm regime (factor >3 times higher than any SC source ever used in this wavelength range). We demonstrate how such an SC source combined with a tunable filter allows high-resolution spectroscopic photoacoustic imaging and the spectroscopy of lipids in the first overtone transition band of C-H bonds (1650-1850 nm). We show the successful discrimination of two different lipids (cholesterol and lipid in adipose tissue) and the photoacoustic cross-sectional scan of lipid-rich adipose tissue at three different locations. The proposed high-pulse energy SC laser paves a new direction towards compact, broadband and cost-effective source for spectroscopic photoacoustic imaging.

  11. Combining parallel detection of proton echo planar spectroscopic imaging (PEPSI) measurements with a data-consistency constraint improves SNR.

    Tsai, Shang-Yueh; Hsu, Yi-Cheng; Chu, Ying-Hua; Kuo, Wen-Jui; Lin, Fa-Hsuan

    2015-12-01

    One major challenge of MRSI is the poor signal-to-noise ratio (SNR), which can be improved by using a surface coil array. Here we propose to exploit the spatial sensitivity of different channels of a coil array to enforce the k-space data consistency (DC) in order to suppress noise and consequently to improve MRSI SNR. MRSI data were collected using a proton echo planar spectroscopic imaging (PEPSI) sequence at 3 T using a 32-channel coil array and were averaged with one, two and eight measurements (avg-1, avg-2 and avg-8). The DC constraint was applied using a regularization parameter λ of 1, 2, 3, 5 or 10. Metabolite concentrations were quantified using LCModel. Our results show that the suppression of noise by applying the DC constraint to PEPSI reconstruction yields up to 32% and 27% SNR gain for avg-1 and avg-2 data with λ = 5, respectively. According to the reported Cramer-Rao lower bounds, the improvement in metabolic fitting was significant (p < 0.01) when the DC constraint was applied with λ ≥ 2. Using the DC constraint with λ = 3 or 5 can minimize both root-mean-square errors and spatial variation for all subjects using the avg-8 data set as reference values. Our results suggest that MRSI reconstructed with a DC constraint can save around 70% of scanning time to obtain images and spectra with similar SNRs using λ = 5. Copyright © 2015 John Wiley & Sons, Ltd.

  12. Image motion compensation by area correlation and centroid tracking of solar surface features

    Nein, M.E.; Mcintosh, W.R.; Cumings, N.P.

    1983-07-01

    An experimental solar correlation tracker was tested and evaluated on a ground-based solar magnetograph. Using sunspots as fixed targets, tracking error signals were derived by which the telescope image was stabilized against wind induced perturbations. Two methods of stabilization were investigated mechanical stabilization of the image by controlled two-axes motion of an active optical element in the telescope beam, and electronic stabilization by biasing of the electron scan in the recording camera. Both approaches have demonstrated telescope stability of about 0.6 arc sec under random perturbations which can cause the unstabilized image to move up to 120 arc sec at frequencies up to 30 Hz

  13. Image motion compensation by area correlation and centroid tracking of solar surface features

    Nein, M. E.; Mcintosh, W. R.; Cumings, N. P.

    1983-01-01

    An experimental solar correlation tracker was tested and evaluated on a ground-based solar magnetograph. Using sunspots as fixed targets, tracking error signals were derived by which the telescope image was stabilized against wind induced perturbations. Two methods of stabilization were investigated; mechanical stabilization of the image by controlled two-axes motion of an active optical element in the telescope beam, and electronic stabilization by biasing of the electron scan in the recording camera. Both approaches have demonstrated telescope stability of about 0.6 arc sec under random perturbations which can cause the unstabilized image to move up to 120 arc sec at frequencies up to 30 Hz.

  14. Proton spectroscopic imaging of polyacrylamide gel dosimeters for absolute radiation dosimetry

    Murphy, P.S.; Schwarz, A.J.; Leach, M.O.

    2000-01-01

    Proton spectroscopy has been evaluated as a method for quantifying radiation induced changes in polyacrylamide gel dosimeters. A calibration was first performed using BANG-type gel samples receiving uniform doses of 6 MV photons from 0 to 9 Gy in 1 Gy intervals. The peak integral of the acrylic protons belonging to acrylamide and methylenebisacrylamide normalized to the water signal was plotted against absorbed dose. Response was approximately linear within the range 0-7 Gy. A large gel phantom irradiated with three, coplanar 3x3cm square fields to 5.74 Gy at isocentre was then imaged with an echo-filter technique to map the distribution of monomers directly. The image, normalized to the water signal, was converted into an absolute dose map. At the isocentre the measured dose was 5.69 Gy (SD = 0.09) which was in good agreement with the planned dose. The measured dose distribution elsewhere in the sample shows greater errors. A T 2 derived dose map demonstrated a better relative distribution but gave an overestimate of the dose at isocentre of 18%. The data indicate that MR measurements of monomer concentration can complement T 2 -based measurements and can be used to verify absolute dose. Compared with the more usual T 2 measurements for assessing gel polymerization, monomer concentration analysis is less sensitive to parameters such as gel pH and temperature, which can cause ambiguous relaxation time measurements and erroneous absolute dose calculations. (author)

  15. Active and passive spectroscopic imaging in the DIII-D tokamak

    Van Zeeland, M A; Brooks, N H; Burrell, K H; Groebner, R J; Hyatt, A W; Luce, T C; Wade, M R; Yu, J H; Pablant, N; Heidbrink, W W; Solomon, W M

    2010-01-01

    Wide-angle, 2D imaging of Doppler-shifted, Balmer alpha (D α ) emission from high energy injected neutrals, charge exchange recombination (CER) emission from neutral beam interaction with thermal ions and fully stripped impurity ions and visible bremsstrahlung (VB) from the core of DIII-D plasmas has been carried out. Narrowband interference filters were used to isolate the specific wavelength ranges of visible radiation for detection by a tangentially viewing, fast-framing camera. Measurements of the D α emission from fast neutrals injected into the plasma from the low field side reveal the vertical distribution of the beam, its divergence and the variation in its radial penetration with density. Modeling of this emission using both a full Monte Carlo collisional radiative code as well as a simple beam attenuation code coupled to Atomic Data and Analysis Structure emissivity lookup tables yields qualitative agreement, however the absolute magnitudes of the emissivities in the predicted distribution are larger than those measured. Active measurements of carbon CER brightness are in agreement with those made independently along the beam midplane using DIII-D's multichordal, CER spectrometer system, confirming the potential of this technique for obtaining 2D profiles of impurity density. Passive imaging of VB, which can be inverted to obtain local emissivity profiles, is compared with measurements from both a calibrated filter/photomultiplier array and the standard multichordal CER spectrometer system.

  16. Active and passive spectroscopic imaging in the DIII-D tokamak

    Van Zeeland, M A; Brooks, N H; Burrell, K H; Groebner, R J; Hyatt, A W; Luce, T C; Wade, M R [General Atomics, PO Box 85608 San Diego, CA 92186-5608 (United States); Yu, J H; Pablant, N [University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093 (United States); Heidbrink, W W [University of California-Irvine, 4129 Frederick Reines Hall, Irvine, CA 92697 (United States); Solomon, W M, E-mail: vanzeeland@fusion.gat.co [Princeton Plasma Physics Laboratory, PO Box 451, Princeton, NJ 08543 (United States)

    2010-04-15

    Wide-angle, 2D imaging of Doppler-shifted, Balmer alpha (D{sub a}lpha) emission from high energy injected neutrals, charge exchange recombination (CER) emission from neutral beam interaction with thermal ions and fully stripped impurity ions and visible bremsstrahlung (VB) from the core of DIII-D plasmas has been carried out. Narrowband interference filters were used to isolate the specific wavelength ranges of visible radiation for detection by a tangentially viewing, fast-framing camera. Measurements of the D{sub a}lpha emission from fast neutrals injected into the plasma from the low field side reveal the vertical distribution of the beam, its divergence and the variation in its radial penetration with density. Modeling of this emission using both a full Monte Carlo collisional radiative code as well as a simple beam attenuation code coupled to Atomic Data and Analysis Structure emissivity lookup tables yields qualitative agreement, however the absolute magnitudes of the emissivities in the predicted distribution are larger than those measured. Active measurements of carbon CER brightness are in agreement with those made independently along the beam midplane using DIII-D's multichordal, CER spectrometer system, confirming the potential of this technique for obtaining 2D profiles of impurity density. Passive imaging of VB, which can be inverted to obtain local emissivity profiles, is compared with measurements from both a calibrated filter/photomultiplier array and the standard multichordal CER spectrometer system.

  17. Wide Field-of-View Soft X-Ray Imaging for Solar Wind-Magnetosphere Interactions

    Walsh, B. M.; Collier, M. R.; Kuntz, K. D.; Porter, F. S.; Sibeck, D. G.; Snowden, S. L.; Carter, J. A.; Collado-Vega, Y.; Connor, H. K.; Cravens, T. E.; hide

    2016-01-01

    Soft X-ray imagers can be used to study the mesoscale and macroscale density structures that occur whenever and wherever the solar wind encounters neutral atoms at comets, the Moon, and both magnetized and unmagnetized planets. Charge exchange between high charge state solar wind ions and exospheric neutrals results in the isotropic emission of soft X-ray photons with energies from 0.1 to 2.0 keV. At Earth, this process occurs primarily within the magnetosheath and cusps. Through providing a global view, wide field-of-view imaging can determine the significance of the various proposed solar wind-magnetosphere interaction mechanisms by evaluating their global extent and occurrence patterns. A summary of wide field-of-view (several to tens of degrees) soft X-ray imaging is provided including slumped micropore microchannel reflectors, simulated images, and recent flight results.

  18. EIT: Solar corona synoptic observations from SOHO with an Extreme-ultraviolet Imaging Telescope

    Delaboudiniere, J. P.; Gabriel, A. H.; Artzner, G. E.; Michels, D. J.; Dere, K. P.; Howard, R. A.; Catura, R.; Stern, R.; Lemen, J.; Neupert, W.

    1988-01-01

    The Extreme-ultraviolet Imaging Telescope (EIT) of SOHO (solar and heliospheric observatory) will provide full disk images in emission lines formed at temperatures that map solar structures ranging from the chromospheric network to the hot magnetically confined plasma in the corona. Images in four narrow bandpasses will be obtained using normal incidence multilayered optics deposited on quadrants of a Ritchey-Chretien telescope. The EIT is capable of providing a uniform one arc second resolution over its entire 50 by 50 arc min field of view. Data from the EIT will be extremely valuable for identifying and interpreting the spatial and temperature fine structures of the solar atmosphere. Temporal analysis will provide information on the stability of these structures and identify dynamical processes. EIT images, issued daily, will provide the global corona context for aid in unifying the investigations and in forming the observing plans for SOHO coronal instruments.

  19. Study of oxide/metal/oxide thin films for transparent electronics and solar cells applications by spectroscopic ellipsometry

    Mihaela Girtan

    2017-05-01

    Full Text Available A comprehensive study of a class of Oxide/Metal/Oxide (Oxide = ITO, AZO, TiO2 and Bi2O3, Metal = Au thin films was done by correlating the spectrophotometric studies with the ellispometric models. Films were deposited by successive sputtering from metallic targets In:Sn, Zn:Al, Ti and Bi in reactive atmosphere (for the oxide films and respective inert atmosphere (for the metallic Au interlayer films on glass substrates. The measurements of optical constants n—the refractive index and k—the extinction coefficient, at different incident photon energies for single oxide films and also for the three layers films oxide/metal/oxide samples were made using the spectroscopic ellipsometry (SE technique. The ellipsometry modelling process was coupled with the recorded transmission spectra data of a double beam spectrophotometer and the best fitting parameters were obtained not only by fitting the n and k experimental data with the dispersion fitting curves as usual is practiced in the most reported data in literature, but also by comparing the calculated the transmission coefficient from ellipsometry with the experimental values obtained from direct spectrophotometry measurements. In this way the best dispersion model was deduced for each sample. Very good correlations were obtained for the other different thin films characteristics such as the films thickness, optical band gap and electrical resistivity obtained by other measurements and calculation techniques. The ellipsometric modelling, can hence give the possibility in the future to predict, by ellipsometric simulations, the proper device architecture in function of the preferred optical and electrical properties.

  20. Solar occultation images analysis using Zernike polynomials ­— an ALTIUS imaging spectrometer application

    Dekemper, Emmanuel; Fussen, Didier; Loodts, Nicolas; Neefs, Eddy

    The ALTIUS (Atmospheric Limb Tracker for the Investigation of the Upcoming Stratosphere) instrument is a major project of the Belgian Institute for Space Aeronomy (BIRA-IASB) in Brussels, Belgium. It has been designed to profit from the benefits of the limb scattering ge-ometry (vertical resolution, global coverage,...), while providing better accuracy on the tangent height knowledge than classical "knee" methods used by scanning spectrometers. The optical concept is based on 3 AOTF's (UV-Vis-NIR) responsible for the instantaneous spectral filtering of the incoming image (complete FOV larger than 100km x 100km at tangent point), ranging from 250nm to 1800nm, with a moderate resolution of a few nm and a typical acquisition time of 1-10s per image. While the primary goal of the instrument is the measurement of ozone with a good vertical resolution, the ability to record full images of the limb can lead to other applications, like solar occultations. With a pixel FOV of 200rad, the full high-sun image is formed of 45x45 pixels, which is sufficient for pattern recognition using moments analysis for instance. The Zernike polynomials form a complete othogonal set of functions over the unit circle. It is well suited for images showing circular shape. Any such image can then be decomposed into a finite set of weighted polynomials, the weighting is called the moments. Due to atmospheric refraction, the sun shape is modified during apparent sunsets and sunrises. The sun appears more flattened which leads to a modification of its zernike moment description. A link between the pressure or the temperature profile (equivalent to air density through the perfect gas law and the hydrostatic equation) and the Zernike moments of a given image can then be made and used to retrieve these atmospheric parameters, with the advantage that the whole sun is used and not only central or edge pixels. Some retrievals will be performed for different conditions and the feasibility of the method

  1. Echo-Planar Imaging-Based, J-Resolved Spectroscopic Imaging for Improved Metabolite Detection in Prostate Cancer

    2016-12-01

    post-process the multi-dimensional MRS data from different prostate pathologies . Scope: Improved cancer detection (specificity) in differentiating...MATERIALS AND METHODS Patients Between March 2012 and May 2013, twenty-two patients with PCa with a mean age of 63.8 years (range, 46–79 years), who...tumor voxels, which was confirmed by the pathology report. After reconstruction, the EP-JRESI data were overlaid onto MRI images. MRI and MRSI A body

  2. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging.

    Park, Ilwoo; Hu, Simon; Bok, Robert; Ozawa, Tomoko; Ito, Motokazu; Mukherjee, Joydeep; Phillips, Joanna J; James, C David; Pieper, Russell O; Ronen, Sabrina M; Vigneron, Daniel B; Nelson, Sarah J

    2013-07-01

    High resolution compressed sensing hyperpolarized (13)C magnetic resonance spectroscopic imaging was applied in orthotopic human glioblastoma xenografts for quantitative assessment of spatial variations in (13)C metabolic profiles and comparison with histopathology. A new compressed sensing sampling design with a factor of 3.72 acceleration was implemented to enable a factor of 4 increase in spatial resolution. Compressed sensing 3D (13)C magnetic resonance spectroscopic imaging data were acquired from a phantom and 10 tumor-bearing rats following injection of hyperpolarized [1-(13)C]-pyruvate using a 3T scanner. The (13)C metabolic profiles were compared with hematoxylin and eosin staining and carbonic anhydrase 9 staining. The high-resolution compressed sensing (13)C magnetic resonance spectroscopic imaging data enabled the differentiation of distinct (13)C metabolite patterns within abnormal tissues with high specificity in similar scan times compared to the fully sampled method. The results from pathology confirmed the different characteristics of (13)C metabolic profiles between viable, non-necrotic, nonhypoxic tumor, and necrotic, hypoxic tissue. Copyright © 2012 Wiley Periodicals, Inc.

  3. Towards UV imaging sensors based on single-crystal diamond chips for spectroscopic applications

    De Sio, A. [Department of Astronomy and Space Science, University of Firenze, Largo E. Fermi 2, 50125 Florence (Italy)], E-mail: desio@arcetri.astro.it; Bocci, A. [Department of Astronomy and Space Science, University of Firenze, Largo E. Fermi 2, 50125 Florence (Italy); Bruno, P.; Di Benedetto, R.; Greco, V.; Gullotta, G. [INAF-Astrophysical Observatory of Catania (Italy); Marinelli, M. [INFN-Department of Mechanical Engineering, University of Roma ' Tor Vergata' (Italy); Pace, E. [Department of Astronomy and Space Science, University of Firenze, Largo E. Fermi 2, 50125 Florence (Italy); Rubulotta, D.; Scuderi, S. [INAF-Astrophysical Observatory of Catania (Italy); Verona-Rinati, G. [INFN-Department of Mechanical Engineering, University of Roma ' Tor Vergata' (Italy)

    2007-12-11

    The recent improvements achieved in the Homoepitaxial Chemical Vapour Deposition technique have led to the production of high-quality detector-grade single-crystal diamonds. Diamond-based detectors have shown excellent performances in UV and X-ray detection, paving the way for applications of diamond technology to the fields of space astronomy and high-energy photon detection in harsh environments or against strong visible light emission. These applications are possible due to diamond's unique properties such as its chemical inertness and visible blindness, respectively. Actually, the development of linear array detectors represents the main issue for a full exploitation of diamond detectors. Linear arrays are a first step to study bi-dimensional sensors. Such devices allow one to face the problems related to pixel miniaturisation and of signal read-out from many channels. Immediate applications would be in spectroscopy, where such arrays are preferred. This paper reports on the development of imaging detectors made by our groups, starting from the material growth and characterisation, through the design, fabrication and packaging of 2xn pixel arrays, to their electro-optical characterisation in terms of UV sensitivity, uniformity of the response and to the development of an electronic circuit suitable to read-out very low photocurrent signals. The detector and its electronic read-out were then tested using a 2x5 pixel array based on a single-crystal diamond. The results will be discussed in the framework of the development of an imager device for X-UV astronomy applications in space missions.

  4. Spectroscopic CZT detectors development for x- and gamma-ray imaging instruments

    Quadrini, Egidio M.; Uslenghi, Michela; Alderighi, Monica; Casini, Fabio; D'Angelo, Sergio; Fiorini, Mauro; La Palombara, Nicola; Mancini, Marcello; Monti, Serena; Bazzano, Angela; Di Cosimo, Sergio; Frutti, Massimo; Natalucci, Lorenzo; Ubertini, Pietro; Guadalupi, Giuseppe M.; Sassi, Matteo; Negri, Barbara

    2007-09-01

    In the context of R&D studies financed by the Italian Space Agency (ASI), a feasibility study to evaluate the Italian Industry interest in medium-large scale production of enhanced CZT detectors has been performed by an Italian Consortium. The R&D investment aims at providing in-house source of high quality solid state spectrometers for Space Astrophysics applications. As a possible spin-off industrial applications to Gamma-ray devices for non-destructive inspections in medical, commercial and security fields have been considered by ASI. The short term programme mainly consists of developing proprietary procedures for 2-3" CZT crystals growth, including bonding and contact philosophy, and a newly designed low-power electronics readout chain. The prototype design and breadboarding is based on a fast signal AD conversion with the target in order to perform a new run for an already existing low-power (digital photon energy reconstruction with particular care for multiple events and polarimetry evaluations. Scientific requirement evaluations for Space Astrophysics Satellite applications have been carried out in parallel, targeted to contribute to the ESA Cosmic Vision 2015-2025 Announcement of Opportunity. Detailed accommodation studies are undergoing, as part of this programme, to size a "Large area arcsecond angular resolution Imager" for the Gamma Ray Imager satellite (Knödlseder et al., this conference).and a new Gamma-ray Wide Field Camera for the "EDGE" proposal (Piro et al., this conference). Finally, an extended market study for cost analysis evaluation in view of the foreseen massive detector production has been performed.

  5. Assessment of the variations in fat content in normal liver using a fast MR imaging method in comparison with results obtained by spectroscopic imaging

    Irwan, Roy; Edens, Mireille A.; Sijens, Paul E.

    2008-01-01

    A recently published Dixon-based MRI method for quantifying liver fat content using dual-echo breath-hold gradient echo imaging was validated by phantom experiments and compared with results of biopsy in two patients (Radiology 2005;237:1048-1055). We applied this method in ten healthy volunteers and compared the outcomes with the results of MR spectroscopy (MRS), the gold standard in quantifying liver fat content. Novel was the use of spectroscopic imaging yielding the variations in fat content across the liver rather than a single value obtained by single voxel MRS. Compared with the results of MRS, liver fat content according to MRI was too high in nine subjects (range 3.3-10.7% vs. 0.9-7.7%) and correct in one (21.1 vs. 21.3%). Furthermore, in one of the ten subjects the MRI fat content according to the Dixon-based MRI method was incorrect due to a (100-x) versus x percent lipid content mix-up. The second problem was fixed by a minor adjustment of the MRI algorithm. Despite systematic overestimation of liver fat contents by MRI, Spearman's correlation between the adjusted MRI liver fat contents with MRS was high (r = 0.927, P < 0.001). Even after correction of the algorithm, the problem remaining with the Dixon-based MRI method for the assessment of liver fat content,is that, at the lower end range, liver fat content is systematically overestimated by 4%. (orig.)

  6. A spectroscopic approach to imaging and quantification of cartilage lesions in human knee joints

    Johansson, A; Oeberg, P A; Sundqvist, T; Kuiper, J-H

    2011-01-01

    We have previously described a technology based on diffuse reflectance of broadband light for measuring joint articular cartilage thickness, utilizing that optical absorption is different in cartilage and subchondral bone. This study is the first evaluation of the technology in human material. We also investigated the prospects of cartilage lesion imaging, with the specific aim of arthroscopic integration. Cartilage thickness was studied ex vivo in a number of sites (n = 87) on human knee joint condyles, removed from nine patients during total knee replacement surgery. A reflectance spectrum was taken at each site and the cartilage thickness was estimated using the blue, green, red and near-infrared regions of the spectrum, respectively. Estimated values were compared with reference cartilage thickness values (taken after sample slicing) using an exponential model. Two-dimensional Monte Carlo simulations were performed in a theoretical analysis of the experimental results. The reference cartilage thickness of the investigated sites was 1.60 ± 1.30 mm (mean ± SD) in the range 0-4.2 mm. Highest correlation coefficients were seen for the calculations based on the near-infrared region after normalization to the red region (r = 0.86) and for the green region (r = 0.80).

  7. 7 Tesla proton magnetic resonance spectroscopic imaging in adult X-linked adrenoleukodystrophy

    Ratai, Eva; Kok, Trina; Wiggins, Christopher; Wiggins, Graham; Grant, Ellen; Gagoski, Borjan; O'Neill, Gilmore; Adalsteinsson, Elfar; Eichler, Florian

    2010-01-01

    Background Adult patients with X-linked adrenoleukodystrophy (X-ALD) remain at risk for progressive neurological deterioration. Phenotypes vary in their pathology, ranging from axonal degeneration to inflammatory demyelination. The severity of symptoms is poorly explained by conventional imaging. Objective To test the hypothesis that neurochemistry in normal appearing brain differs among adult phenotypes of X-ALD, and that neurochemical changes correlate with the severity of symptoms. Patients and Methods Using a 7 Tesla scanner we performed structural and proton MRSI in 13 adult patients with X-ALD, including 4 patients with adult cerebral ALD (ACALD), 5 with adrenomyeloneuropathy (AMN) and 4 female heterozygotes. Studies were also performed in nine healthy controls. Results Among adult X-ALD phenotypes, MI/Cr was 46% higher and Cho/Cr 21% higher in normal appearing white matter of ACALD compared to AMN (p Tesla proton MRSI reveals differences in the neurochemistry of ACALD but is unable to distinguish AMN from female heterozygotes. MI/Cr correlates with the severity of the symptoms and may be a meaningful biomarker in adult X-ALD. PMID:19001168

  8. EUV imager and spectrometer for LYOT and solar orbiter space missions

    Millard, Anne; Lemaire, Philippe; Vial, Jean-Claude

    2017-11-01

    In the 2010 horizon, solar space missions such as LYOT and Solar Orbiter will allow high cadence UV observations of the Sun at spatial and spectral resolution never obtained before. To reach these goals, the two missions could take advantage of spectro-imagers. A reflective only optical solution for such an instrument is described in this paper and the first results of the mock-up being built at IAS are shown.

  9. FIVE YEARS OF SYNTHESIS OF SOLAR SPECTRAL IRRADIANCE FROM SDID/SISA AND SDO /AIA IMAGES

    Fontenla, J. M. [NorthWest Research Associates, Boulder, CO 80301 (United States); Codrescu, M. [Space Weather Prediction Center, National Oceanic and Atmospheric Administration, Boulder, CO 80305 (United States); Fedrizzi, M.; Fuller-Rowell, T. [Cooperative Institute for Research in Environmental Sciences, University of Colorado Boulder, Boulder, CO 80309 (United States); Hill, F. [National Solar Observatory, Boulder, CO 80303 (United States); Landi, E. [Department of Climate and Space Science and Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Woods, T., E-mail: johnf@digidyna.com [Laboratory for Atmospheric and Space Physics, University of Colorado Boulder, Boulder, CO 80303 (United States)

    2017-01-01

    In this paper we describe the synthetic solar spectral irradiance (SSI) calculated from 2010 to 2015 using data from the Atmospheric Imaging Assembly (AIA) instrument, on board the Solar Dynamics Observatory spacecraft. We used the algorithms for solar disk image decomposition (SDID) and the spectral irradiance synthesis algorithm (SISA) that we had developed over several years. The SDID algorithm decomposes the images of the solar disk into areas occupied by nine types of chromospheric and 5 types of coronal physical structures. With this decomposition and a set of pre-computed angle-dependent spectra for each of the features, the SISA algorithm is used to calculate the SSI. We discuss the application of the basic SDID/SISA algorithm to a subset of the AIA images and the observed variation occurring in the 2010–2015 period of the relative areas of the solar disk covered by the various solar surface features. Our results consist of the SSI and total solar irradiance variations over the 2010–2015 period. The SSI results include soft X-ray, ultraviolet, visible, infrared, and far-infrared observations and can be used for studies of the solar radiative forcing of the Earth’s atmosphere. These SSI estimates were used to drive a thermosphere–ionosphere physical simulation model. Predictions of neutral mass density at low Earth orbit altitudes in the thermosphere and peak plasma densities at mid-latitudes are in reasonable agreement with the observations. The correlation between the simulation results and the observations was consistently better when fluxes computed by SDID/SISA procedures were used.

  10. The rise of non-imaging optics for rooftop solar collectors

    Rosengarten, Gary; Stanley, Cameron; Ferrari, Dave; Blakers, Andrew; Ratcliff, Tom

    2016-09-01

    In this paper we explore the use of non-imaging optics for rooftop solar concentrators. Specifically, we focus on compound parabolic concentrators (CPCs), which form an ideal shape for cylindrical thermal absorbers, and for linear PV cells (allowing the use of more expensive but more efficient cells). Rooftops are ideal surfaces for solar collectors as they face the sky and are generally free, unused space. Concentrating solar radiation adds thermodynamic value to thermal collectors (allowing the attainment of higher temperature) and can add efficiency to PV electricity generation. CPCs allow that concentration over the day without the need for tracking. Hence they have become ubiquitous in applications requiring low concentration.

  11. Imaging x-ray spectrometer to study solar activity in conjunction with the SCADM program

    Blake, R.L.

    1979-01-01

    An experiment is proposed to study solar active region dynamics and evolution. It will greatly extend the range of capabilities provided by the Solar Maximum Mission. The larger volume and weight capacity of a shuttle launch make possible an experiment with enough sensitivity to study the fastest known solar phenomena with high spatial and spectral resolution. It will be possible to use high spectral resolving power to image events on a small scale in short time intervals, and it will be possible to use this tremendous diagnostic power from the instant of event onset. Similar sensitivity will be available for the study of active region morphology and evolution

  12. Uniform and non-uniform modes of nanosecond-pulsed dielectric barrier discharge in atmospheric air: fast imaging and spectroscopic measurements of electric field.

    Liu, Chong; Dobrynin, Danil; Fridman, Alexander

    2014-06-25

    In this study, we report experimental results on fast ICCD imaging of development of nanosecond-pulsed dielectric barrier discharge (DBD) in atmospheric air and spectroscopic measurements of electric field in the discharge. Uniformity of the discharge images obtained with nanosecond exposure times were analyzed using chi-square test. The results indicate that DBD uniformity strongly depends on applied (global) electric field in the discharge gap, and is a threshold phenomenon. We show that in the case of strong overvoltage on the discharge gap (provided by fast rise times), there is transition from filamentary to uniform DBD mode which correlates to the corresponding decrease of maximum local electric field in the discharge.

  13. Spectroscopic techniques (Mössbauer spectrometry, NMR, ESR,…) as tools to resolve doubtful NMR images: Study of the craniopharyngioma tumor

    Rimbert, J. N.; Dumas, F.; Lafargue, C.; Kellershohn, C.; Brunelle, F.; Lallemand, D.

    1990-07-01

    Craniopharyngioma, an intracranial tumor, exhibits hyperintensity in the Spin-Echo-T2-NMR image and a hyposignal in the SE-T1-image. However, in some cases (15-20% cases), hypersignals are seen in both SE-T1 and T2-MRI. Using spectroscopic techniques, Mössbauer spectrometry in particular, we have demonstrated that the T1 hypersignal is due to ferritin, dissolved in the cystic liquid, after tumor cell lysis, in the course of time. Other possible reasons inducing a shortening of the T1 relaxation time (presence of lipids, intratumoral hemorrhage) have been rejected.

  14. PREDICTION OF SOLAR FLARES USING UNIQUE SIGNATURES OF MAGNETIC FIELD IMAGES

    Raboonik, Abbas; Safari, Hossein; Alipour, Nasibe [Department of Physics, University of Zanjan, P.O. Box 45195-313, Zanjan (Iran, Islamic Republic of); Wheatland, Michael S., E-mail: raboonik@alumni.znu.ac.ir, E-mail: safari@znu.ac.ir [Sydney Institute for Astronomy, School of Physics, The University of Sydney, NSW 2006 (Australia)

    2017-01-01

    Prediction of solar flares is an important task in solar physics. The occurrence of solar flares is highly dependent on the structure and topology of solar magnetic fields. A new method for predicting large (M- and X-class) flares is presented, which uses machine learning methods applied to the Zernike moments (ZM) of magnetograms observed by the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory for a period of six years from 2010 June 2 to 2016 August 1. Magnetic field images consisting of the radial component of the magnetic field are converted to finite sets of ZMs and fed to the support vector machine classifier. ZMs have the capability to elicit unique features from any 2D image, which may allow more accurate classification. The results indicate whether an arbitrary active region has the potential to produce at least one large flare. We show that the majority of large flares can be predicted within 48 hr before their occurrence, with only 10 false negatives out of 385 flaring active region magnetograms and 21 false positives out of 179 non-flaring active region magnetograms. Our method may provide a useful tool for the prediction of solar flares, which can be employed alongside other forecasting methods.

  15. Automatic Detection of Inactive Solar Cell Cracks in Electroluminescence Images

    Spataru, Sergiu; Hacke, Peter; Sera, Dezso

    2017-01-01

    We propose an algorithm for automatic determination of the electroluminescence (EL) signal threshold level corresponding to inactive solar cell cracks, resulting from their disconnection from the electrical circuit of the cell. The method enables automatic quantification of the cell crack size an...

  16. Automatic Detection of Inactive Solar Cell Cracks in Electroluminescence Images

    Spataru, Sergiu; Hacke, Peter; Sera, Dezso

    2017-01-01

    We propose an algorithm for automatic determination of the electroluminescence (EL) signal threshold level corresponding to inactive solar cell cracks, resulting from their disconnection from the electrical circuit of the cell. The method enables automatic quantification of the cell crack size...

  17. Proton MR spectroscopy in patients with pyogenic brain abscess: MR spectroscopic imaging versus single-voxel spectroscopy

    Hsu, Shuo-Hsiu, E-mail: gerwuver@gmail.com [Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC (China); Chou, Ming-Chung, E-mail: mcchou@kmu.edu.tw [Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC (China); Ko, Cheng-Wen, E-mail: chengwen.ko@gmail.com [Department of Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, ROC (China); Hsu, Shu-Shong, E-mail: sshsu59@yahoo.com [Department of Neurosurgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC (China); Lin, Huey-Shyan, E-mail: sc035@fy.edu.tw [Program of Health-Business Administration, School of Nursing, Fooyin University, Kaohsiung, Taiwan, ROC (China); Fu, Jui-Hsun, E-mail: fujuihsun@gmail.com [Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC (China); Wang, Po-Chin, E-mail: hiscore6@gmail.com [Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC (China); School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC (China); Pan, Huay-Ben, E-mail: panhb@vghks.gov.tw [Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC (China); School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC (China); Lai, Ping-Hong, E-mail: pinghonglai@gmail.com [Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC (China); School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC (China)

    2013-08-15

    Purpose: Single-voxel spectroscopy (SVS) has been the gold standard technique to diagnose the pyogenic abssess. Two-dimensional magnetic resonance spectroscopic imaging (MRSI) is able to provide spatial distribution of metabolic concentration, and is potentially more suitable for differential diagnosis between abscess and necrotic tumors. Therefore, the purpose of this study was to evaluate the equivalence of MRSI and SVS in the detection of the metabolites in pyogenic brain abscesses. Materials and methods: Forty-two patients with pyogenic abscesses were studied by using both SVS and MRSI methods. Two neuroradiologists reviewed the MRS data independently. A κ value was calculated to express inter-reader agreement of the abscesses metabolites, and a correlation coefficient was calculated to show the similarity of two spectra. After consensus judgment of two readers, the binary value of metabolites of pyogenic abscesses (presence or absence) was compared between SVS and MRSI. Results: The consistency of spectral interpretation of the two readers was very good (κ ranged from 0.95 to 1), and the similarity of two spectra was also very high (cc = 0.9 ± 0.05). After consensus judgment of two readers, the sensitivities of MRSI ranged from 91% (acetate) to 100% (amino acids, succinate, lactate, lipid), and the specificities of MRSI were 100% for detecting all metabolites with SVS as reference. Conclusion: SVS and MRSI provide similar metabolites in the cavity of pyogenic brain abscess. With additional metabolic information of cavity wall and contralateral normal-appearing brain tissue, MRSI would be a more suitable technique to differentiate abscesses from necrotic tumors.

  18. Three-dimensional magnetic resonance spectroscopic imaging in the substantia nigra of healthy controls and patients with Parkinson's disease

    Groeger, Adriane; Godau, Jana; Berg, Daniela [University of Tuebingen, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Disease (DZNE), Tuebingen (Germany); Chadzynski, Grzegorz; Klose, Uwe [University Hospital Tuebingen, Department of Diagnostic and Interventional Neuroradiology, Tuebingen (Germany)

    2011-09-15

    To investigate the substantia nigra in patients with Parkinson's disease three-dimensional magnetic resonance spectroscopic imaging with high spatial resolution at 3 Tesla was performed. Regional variations of spectroscopic data between the rostral and caudal regions of the substantia nigra as well as the midbrain tegmentum areas were evaluated in healthy controls and patients with Parkinson's disease. Nine patients with Parkinson's disease and eight age- and gender-matched healthy controls were included in this study. Data were acquired by using three-dimensional magnetic resonance spectroscopic imaging measurements. The ratios between rostral and caudal voxels of the substantia nigra as well as the midbrain tegmentum areas were calculated for the main-metabolites N-acetyl aspartate, creatine, choline, and myo-inositol. Additionally, the metabolite/creatine ratios were calculated. In all subjects spectra of acceptable quality could be obtained with a nominal voxel size of 0.252 ml. The calculated rostral-to-caudal ratios of the metabolites as well as of the metabolite/creatine ratios showed with exception of choline/creatine ratio significant differences between healthy controls and patients with Parkinson's disease. The findings from this study indicate that regional variations in N-acetyl aspartate/creatine ratios in the regions of the substantia nigra may differentiate patients with Parkinson's disease and healthy controls. (orig.)

  19. IMAGING AND SPECTROSCOPIC DIAGNOSTICS ON THE FORMATION OF TWO MAGNETIC FLUX ROPES REVEALED BY SDO/AIA AND IRIS

    Cheng, X.; Ding, M. D.; Fang, C., E-mail: xincheng@nju.edu.cn [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China)

    2015-05-10

    Helical magnetic flux rope (MFR) is a fundamental structure of coronal mass ejections (CMEs) and has been discovered recently to exist as a sigmoidal channel structure prior to its eruption in the EUV high-temperature passbands of the Atmospheric Imaging Assembly (AIA). However, when and where the MFR is built up are still elusive. In this paper, we investigate two MFRs (MFR1 and MFR2) in detail, whose eruptions produced two energetic solar flares and CMEs on 2014 April 18 and 2014 September 10, respectively. The AIA EUV images reveal that for a long time prior to their eruption, both MFR1 and MFR2 are under formation, which is probably through magnetic reconnection between two groups of sheared arcades driven by the shearing and converging flows in the photosphere near the polarity inversion line. At the footpoints of the MFR1, the Interface Region Imaging Spectrograph Si iv, C ii, and Mg ii lines exhibit weak to moderate redshifts and a non-thermal broadening in the pre-flare phase. However, a relatively large blueshift and an extremely strong non-thermal broadening are found at the formation site of the MFR2. These spectral features consolidate the proposition that the reconnection plays an important role in the formation of MFRs. For the MFR1, the reconnection outflow may propagate along its legs, penetrating into the transition region and the chromosphere at the footpoints. For the MFR2, the reconnection probably takes place in the lower atmosphere and results in the strong blueshift and non-thermal broadening for the Mg ii, C ii, and Si iv lines.

  20. Imaging and Spectroscopic Diagnostics on the Formation of Two Magnetic Flux Ropes Revealed by SDO/AIA and IRIS

    Cheng, X.; Ding, M. D.; Fang, C.

    2015-05-01

    Helical magnetic flux rope (MFR) is a fundamental structure of coronal mass ejections (CMEs) and has been discovered recently to exist as a sigmoidal channel structure prior to its eruption in the EUV high-temperature passbands of the Atmospheric Imaging Assembly (AIA). However, when and where the MFR is built up are still elusive. In this paper, we investigate two MFRs (MFR1 and MFR2) in detail, whose eruptions produced two energetic solar flares and CMEs on 2014 April 18 and 2014 September 10, respectively. The AIA EUV images reveal that for a long time prior to their eruption, both MFR1 and MFR2 are under formation, which is probably through magnetic reconnection between two groups of sheared arcades driven by the shearing and converging flows in the photosphere near the polarity inversion line. At the footpoints of the MFR1, the Interface Region Imaging Spectrograph Si iv, C ii, and Mg ii lines exhibit weak to moderate redshifts and a non-thermal broadening in the pre-flare phase. However, a relatively large blueshift and an extremely strong non-thermal broadening are found at the formation site of the MFR2. These spectral features consolidate the proposition that the reconnection plays an important role in the formation of MFRs. For the MFR1, the reconnection outflow may propagate along its legs, penetrating into the transition region and the chromosphere at the footpoints. For the MFR2, the reconnection probably takes place in the lower atmosphere and results in the strong blueshift and non-thermal broadening for the Mg ii, C ii, and Si iv lines.

  1. IMAGING AND SPECTROSCOPIC DIAGNOSTICS ON THE FORMATION OF TWO MAGNETIC FLUX ROPES REVEALED BY SDO/AIA AND IRIS

    Cheng, X.; Ding, M. D.; Fang, C.

    2015-01-01

    Helical magnetic flux rope (MFR) is a fundamental structure of coronal mass ejections (CMEs) and has been discovered recently to exist as a sigmoidal channel structure prior to its eruption in the EUV high-temperature passbands of the Atmospheric Imaging Assembly (AIA). However, when and where the MFR is built up are still elusive. In this paper, we investigate two MFRs (MFR1 and MFR2) in detail, whose eruptions produced two energetic solar flares and CMEs on 2014 April 18 and 2014 September 10, respectively. The AIA EUV images reveal that for a long time prior to their eruption, both MFR1 and MFR2 are under formation, which is probably through magnetic reconnection between two groups of sheared arcades driven by the shearing and converging flows in the photosphere near the polarity inversion line. At the footpoints of the MFR1, the Interface Region Imaging Spectrograph Si iv, C ii, and Mg ii lines exhibit weak to moderate redshifts and a non-thermal broadening in the pre-flare phase. However, a relatively large blueshift and an extremely strong non-thermal broadening are found at the formation site of the MFR2. These spectral features consolidate the proposition that the reconnection plays an important role in the formation of MFRs. For the MFR1, the reconnection outflow may propagate along its legs, penetrating into the transition region and the chromosphere at the footpoints. For the MFR2, the reconnection probably takes place in the lower atmosphere and results in the strong blueshift and non-thermal broadening for the Mg ii, C ii, and Si iv lines

  2. A High-resolution Multi-wavelength Simultaneous Imaging System with Solar Adaptive Optics

    Rao, Changhui; Zhu, Lei; Gu, Naiting; Rao, Xuejun; Zhang, Lanqiang; Bao, Hua; Kong, Lin; Guo, Youming; Zhong, Libo; Ma, Xue’an; Li, Mei; Wang, Cheng; Zhang, Xiaojun; Fan, Xinlong; Chen, Donghong; Feng, Zhongyi; Wang, Xiaoyun; Wang, Zhiyong, E-mail: gunaiting@ioe.ac.cn [The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, P.O. Box 350, Shuangliu, Chengdu 610209, Sichuan (China)

    2017-10-01

    A high-resolution multi-wavelength simultaneous imaging system from visible to near-infrared bands with a solar adaptive optics system, in which seven imaging channels, including the G band (430.5 nm), the Na i line (589 nm), the H α line (656.3 nm), the TiO band (705.7 nm), the Ca ii IR line (854.2 nm), the He i line (1083 nm), and the Fe i line (1565.3 nm), are chosen, is developed to image the solar atmosphere from the photosphere layer to the chromosphere layer. To our knowledge, this is the solar high-resolution imaging system with the widest spectral coverage. This system was demonstrated at the 1 m New Vaccum Solar Telescope and the on-sky high-resolution observational results were acquired. In this paper, we will illustrate the design and performance of the imaging system. The calibration and the data reduction of the system are also presented.

  3. The spectrometer/telescope for imaging X-rays on board the ESA Solar Orbiter spacecraft

    Krucker, S.; Benz, A. O.; Hurford, G.J.; Arnold, N.G.; Orleanski, P.; Groebelbauer, H.-P.; Casadei, D.; Kobler, S.; Iseli, L.; Wiehl, H.J.; Fárník, František

    2013-01-01

    Roč. 732, December (2013), s. 295-298 ISSN 0168-9002. [Vienna Conference on Instrumentation /13./. Vienna, 11.02.2013-15.02.2013] Institutional support: RVO:67985815 Keywords : Fourier optics * X-ray imaging * solar flares Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics OBOR OECD: Astronomy (including astrophysics,space science) Impact factor: 1.316, year: 2013

  4. Design of a Solar Tracking System Using the Brightest Region in the Sky Image Sensor.

    Wei, Ching-Chuan; Song, Yu-Chang; Chang, Chia-Chi; Lin, Chuan-Bi

    2016-11-25

    Solar energy is certainly an energy source worth exploring and utilizing because of the environmental protection it offers. However, the conversion efficiency of solar energy is still low. If the photovoltaic panel perpendicularly tracks the sun, the solar energy conversion efficiency will be improved. In this article, we propose an innovative method to track the sun using an image sensor. In our method, it is logical to assume the points of the brightest region in the sky image representing the location of the sun. Then, the center of the brightest region is assumed to be the solar-center, and is mathematically calculated using an embedded processor (Raspberry Pi). Finally, the location information on the sun center is sent to the embedded processor to control two servo motors that are capable of moving both horizontally and vertically to track the sun. In comparison with the existing sun tracking methods using image sensors, such as the Hough transform method, our method based on the brightest region in the sky image remains accurate under conditions such as a sunny day and building shelter. The practical sun tracking system using our method was implemented and tested. The results reveal that the system successfully captured the real sun center in most weather conditions, and the servo motor system was able to direct the photovoltaic panel perpendicularly to the sun center. In addition, our system can be easily and practically integrated, and can operate in real-time.

  5. LOFAR tied-array imaging of Type III solar radio bursts

    Morosan, D.E.; et al., [Unknown; Hessels, J.W.T.; Markoff, S.

    2014-01-01

    Context. The Sun is an active source of radio emission which is often associated with energetic phenomena such as solar flares and coronal mass ejections (CMEs). At low radio frequencies (<100 MHz), the Sun has not been imaged extensively because of the instrumental limitations of previous radio

  6. LOFAR tied-array imaging of Type III solar radio bursts

    Morosan, D.E.; Gallagher, P.T.; Zucca, P.; Fallows, R.; Carley, E.P.; Mann, G.; Bisi, M.M.; Kerdraon, A.; Avruch, I.M.; Bentum, Marinus Jan; Bernardi, G.; Best, P.; Bonafede, A.; Bregman, J.; Breitling, F.

    2014-01-01

    Context: The Sun is an active source of radio emission which is often associated with energetic phenomena such as solar flares and coronal mass ejections (CMEs). At low radio frequencies (<100 MHz), the Sun has not been imaged extensively because of the instrumental limitations of previous radio

  7. Design of a Solar Tracking System Using the Brightest Region in the Sky Image Sensor

    Ching-Chuan Wei

    2016-11-01

    Full Text Available Solar energy is certainly an energy source worth exploring and utilizing because of the environmental protection it offers. However, the conversion efficiency of solar energy is still low. If the photovoltaic panel perpendicularly tracks the sun, the solar energy conversion efficiency will be improved. In this article, we propose an innovative method to track the sun using an image sensor. In our method, it is logical to assume the points of the brightest region in the sky image representing the location of the sun. Then, the center of the brightest region is assumed to be the solar-center, and is mathematically calculated using an embedded processor (Raspberry Pi. Finally, the location information on the sun center is sent to the embedded processor to control two servo motors that are capable of moving both horizontally and vertically to track the sun. In comparison with the existing sun tracking methods using image sensors, such as the Hough transform method, our method based on the brightest region in the sky image remains accurate under conditions such as a sunny day and building shelter. The practical sun tracking system using our method was implemented and tested. The results reveal that the system successfully captured the real sun center in most weather conditions, and the servo motor system was able to direct the photovoltaic panel perpendicularly to the sun center. In addition, our system can be easily and practically integrated, and can operate in real-time.

  8. Proposal of AAA-battery-size one-shot ATR Fourier spectroscopic imager for on-site analysis: Simultaneous measurement of multi-components with high accuracy

    Hosono, Satsuki; Qi, Wei; Sato, Shun; Suzuki, Yo; Fujiwara, Masaru; Hiramatsu, Hiroyuki; Suzuki, Satoru; Abeygunawardhana, P. K. W.; Wada, Kenji; Nishiyama, Akira; Ishimaru, Ichiro

    2015-03-01

    For simultaneous measurement of multi-components on-site like factories, the ultra-compact (diameter: 9[mm], length: 45[mm], weight: 200[g]) one-shot ATR (Attenuated Total Reflection) Fourier spectroscopic imager was proposed. Because the proposed one-shot Fourier spectroscopic imaging is based on spatial-phase-shift interferometer, interferograms could be obtained with simple optical configurations. We introduced the transmission-type relativeinclined phase-shifter, that was constructed with a cuboid prism and a wedge prism, onto the optical Fourier transform plane of infinity corrected optical systems. And also, small light-sources and cameras in the mid-infrared light region, whose size are several millimeter on a side, are essential components for the ultra-compact spectroscopic configuration. We selected the Graphite light source (light source area: 1.7×1.7[mm], maker: Hawkeye technologies) whose radiation factor was high. Fortunately, in these days we could apply the cost-effective 2-dimensional light receiving device for smartphone (e.g. product name: LEPTON, maker: FLIR, price: around 400USD). In the case of alcoholic drinks factory, conventionally workers measure glucose and ethanol concentrations by bringing liquid solution back to laboratories every day. The high portable spectroscopy will make it possible to measure multi-components simultaneously on manufacturing scene. But we found experimentally that absorption spectrum of glucose and water and ethanol were overlapped each other in near infrared light region. But for mid-infrared light region, we could distinguish specific absorption peaks of glucose (@10.5[μm]) and ethanol (@11.5[μm]) independently from water absorption. We obtained standard curve between absorption (@9.6[μm]) and ethanol concentration with high correlation coefficient 0.98 successfully by ATR imaging-type 2-dimensional Fourier spectroscopy (wavelength resolution: 0.057[μm]) with the graphite light source (maker: Hawkeye

  9. The CubeSat Imaging X-ray Solar Spectrometer (CubIXSS) Mission Concept

    Caspi, Amir; Shih, Albert Y.; Warren, Harry; DeForest, Craig; Laurent, Glenn Thomas; Schwartz, Richard A.; Woods, Thomas N.; Mason, James; Palo, Scott; Steslicki, Marek; Sylwester, Janusz; Gburek, Szymon; Mrozek, Tomasz; Kowalinski, Miroslaw; Torre, Gabriele; Crowley, Geoffrey; Schattenburg, Mark

    2017-08-01

    Solar soft X-ray (SXR) observations provide important diagnostics of plasma heating, during solar flares and quiescent times. Spectrally- and temporally-resolved measurements are crucial for understanding the dynamics, origins, and evolution of these energetic processes, providing probes both into the temperature distributions and elemental compositions of hot plasmas; spatially-resolved measurements are critical for understanding energy transport and mass flow. A better understanding of the thermal plasma improves our understanding of the relationships between particle acceleration, plasma heating, and the underlying release of magnetic energy during reconnection. We introduce a new proposed small satellite mission, the CubeSat Imaging X-ray Solar Spectrometer (CubIXSS), to measure spectrally- and spatially-resolved SXRs from the quiescent and flaring Sun from a 6U CubeSat platform in low-Earth orbit during a nominal 1-year mission. CubIXSS includes the Amptek X123-FastSDD silicon drift detector, a low-noise, commercial off-the-shelf (COTS) instrument enabling solar SXR spectroscopy from ~0.5 to ~30 keV with ~0.15 keV FWHM spectral resolution with low power, mass, and volume requirements. Multiple detectors and tailored apertures provide sensitivity to a wide range of solar conditions, optimized for a launch during solar minimum. The precise spectra from these instruments will provide detailed measurements of the coronal temperature distribution and elemental abundances from the quiet Sun to active regions and flares. CubIXSS also includes a novel spectro-spatial imager -- the first ever solar imager on a CubeSat -- utilizing a custom pinhole camera and Chandra-heritage X-ray transmission diffraction grating to provide spatially- resolved, full-Sun imaging spectroscopy from ~0.1 to ~10 keV, with ~25 arcsec and ~0.1 Å FWHM spatial and spectral resolutions, respectively. MOXSI’s unique capabilities enable SXR spectroscopy and temperature diagnostics of individual

  10. H-1 MR spectroscopic imaging detects prolonged elevation of lactate and increased Ch/NAA ratio in patients with focal cerebral ischemia

    van Rijen, P.C.; Tulleken, C.A.F.; den Hollander, J.A.; Luyten, P.R.

    1989-01-01

    H-1 MR spectroscopy of patients with a recent stroke (range, 78 hours to 18 days after stroke) showed an increased Ch/NAA ratio in a large ischemic region of the brain, while lactate was increased in the center of the infarct. A spectroscopic image taken 8 months after the stroke did not show any increased lactate; however, the Ch/NAA ratio image still showed increased intensity even in regions that looked normal on the MR images. H-1 MR spectra measured during clinical recovery (range 10-48 days) still showed elevated lactate compared with control regions, although lactate was lower than in the acute phase. This suggests on ongoing anaerobic glycolysis in the metabolically compromised penumbra

  11. Technical note: Evaluation of the uncertainties in (choline+creatine)/citrate ratios measured by proton MR spectroscopic imaging in patients suspicious for prostate cancer

    Zbyn, S.; Krssak, M.; Memarsadeghi, M.; Gholami, B.; Haitel, A.; Weber, M.; Helbich, T.H.; Trattnig, S.; Moser, E.; Gruber, S.

    2014-07-15

    The presented evaluation of the relative uncertainty (δ'CCC) of the (choline + creatine)/citrate (CC/C) ratios can provide objective information about the quality and diagnostic value of prostate MR spectroscopic imaging data. This information can be combined with the numeric values of CC/C ratios and provides metabolic-quality maps enabling accurate cancer detection and user-independent data evaluation. In addition, the prostate areas suffering most from the low precision of CC/C ratios (e. g., prostate base) were identified.

  12. Magnetic resonance spectroscopic imaging of benign prostatic tissue: findings at 3.0 T compared to 1.5 T—initial experience☆

    Chitkara, Munish; Westphalen, Antonio; Kurhanewicz, John; Qayyum, Aliya; Poder, Liina; Reed, Galen; Coakley, Fergus V.

    2013-01-01

    In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer. PMID:21724122

  13. 3-Dimensional Magnetic Resonance Spectroscopic Imaging at 3 Tesla for Early Response Assessment of Glioblastoma Patients During External Beam Radiation Therapy

    Muruganandham, Manickam; Clerkin, Patrick P.; Smith, Brian J.; Anderson, Carryn M.; Morris, Ann; Capizzano, Aristides A.; Magnotta, Vincent; McGuire, Sarah M.; Smith, Mark C.; Bayouth, John E.; Buatti, John M.

    2014-01-01

    Purpose: To evaluate the utility of 3-dimensional magnetic resonance (3D-MR) proton spectroscopic imaging for treatment planning and its implications for early response assessment in glioblastoma multiforme. Methods and Materials: Eighteen patients with newly diagnosed, histologically confirmed glioblastoma had 3D-MR proton spectroscopic imaging (MRSI) along with T2 and T1 gadolinium-enhanced MR images at simulation and at boost treatment planning after 17 to 20 fractions of radiation therapy. All patients received standard radiation therapy (RT) with concurrent temozolomide followed by adjuvant temozolomide. Imaging for response assessment consisted of MR scans every 2 months. Progression-free survival was defined by the criteria of MacDonald et al. MRSI images obtained at initial simulation were analyzed for choline/N-acetylaspartate ratios (Cho/NAA) on a voxel-by-voxel basis with abnormal activity defined as Cho/NAA ≥2. These images were compared on anatomically matched MRSI data collected after 3 weeks of RT. Changes in Cho/NAA between pretherapy and third-week RT scans were tested using Wilcoxon matched-pairs signed rank tests and correlated with progression-free survival, radiation dose and location of recurrence using Cox proportional hazards regression. Results: After a median follow-up time of 8.6 months, 50% of patients had experienced progression based on imaging. Patients with a decreased or stable mean or median Cho/NAA values had less risk of progression (P<.01). Patients with an increase in mean or median Cho/NAA values at the third-week RT scan had a significantly greater chance of early progression (P<.01). An increased Cho/NAA at the third-week MRSI scan carried a hazard ratio of 2.72 (95% confidence interval, 1.10-6.71; P=.03). Most patients received the prescription dose of RT to the Cho/NAA ≥2 volume, where recurrence most often occurred. Conclusion: Change in mean and median Cho/NAA detected at 3 weeks was a significant predictor of

  14. 3-Dimensional Magnetic Resonance Spectroscopic Imaging at 3 Tesla for Early Response Assessment of Glioblastoma Patients During External Beam Radiation Therapy

    Muruganandham, Manickam; Clerkin, Patrick P. [Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (United States); Smith, Brian J. [Department of Biostatistics, University of Iowa Hospitals and Clinics, Iowa City, Iowa (United States); Anderson, Carryn M.; Morris, Ann [Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (United States); Capizzano, Aristides A.; Magnotta, Vincent [Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (United States); McGuire, Sarah M.; Smith, Mark C.; Bayouth, John E. [Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (United States); Buatti, John M., E-mail: john-buatti@uiowa.edu [Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (United States)

    2014-09-01

    Purpose: To evaluate the utility of 3-dimensional magnetic resonance (3D-MR) proton spectroscopic imaging for treatment planning and its implications for early response assessment in glioblastoma multiforme. Methods and Materials: Eighteen patients with newly diagnosed, histologically confirmed glioblastoma had 3D-MR proton spectroscopic imaging (MRSI) along with T2 and T1 gadolinium-enhanced MR images at simulation and at boost treatment planning after 17 to 20 fractions of radiation therapy. All patients received standard radiation therapy (RT) with concurrent temozolomide followed by adjuvant temozolomide. Imaging for response assessment consisted of MR scans every 2 months. Progression-free survival was defined by the criteria of MacDonald et al. MRSI images obtained at initial simulation were analyzed for choline/N-acetylaspartate ratios (Cho/NAA) on a voxel-by-voxel basis with abnormal activity defined as Cho/NAA ≥2. These images were compared on anatomically matched MRSI data collected after 3 weeks of RT. Changes in Cho/NAA between pretherapy and third-week RT scans were tested using Wilcoxon matched-pairs signed rank tests and correlated with progression-free survival, radiation dose and location of recurrence using Cox proportional hazards regression. Results: After a median follow-up time of 8.6 months, 50% of patients had experienced progression based on imaging. Patients with a decreased or stable mean or median Cho/NAA values had less risk of progression (P<.01). Patients with an increase in mean or median Cho/NAA values at the third-week RT scan had a significantly greater chance of early progression (P<.01). An increased Cho/NAA at the third-week MRSI scan carried a hazard ratio of 2.72 (95% confidence interval, 1.10-6.71; P=.03). Most patients received the prescription dose of RT to the Cho/NAA ≥2 volume, where recurrence most often occurred. Conclusion: Change in mean and median Cho/NAA detected at 3 weeks was a significant predictor of

  15. 3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy.

    Muruganandham, Manickam; Clerkin, Patrick P; Smith, Brian J; Anderson, Carryn M; Morris, Ann; Capizzano, Aristides A; Magnotta, Vincent; McGuire, Sarah M; Smith, Mark C; Bayouth, John E; Buatti, John M

    2014-09-01

    To evaluate the utility of 3-dimensional magnetic resonance (3D-MR) proton spectroscopic imaging for treatment planning and its implications for early response assessment in glioblastoma multiforme. Eighteen patients with newly diagnosed, histologically confirmed glioblastoma had 3D-MR proton spectroscopic imaging (MRSI) along with T2 and T1 gadolinium-enhanced MR images at simulation and at boost treatment planning after 17 to 20 fractions of radiation therapy. All patients received standard radiation therapy (RT) with concurrent temozolomide followed by adjuvant temozolomide. Imaging for response assessment consisted of MR scans every 2 months. Progression-free survival was defined by the criteria of MacDonald et al. MRSI images obtained at initial simulation were analyzed for choline/N-acetylaspartate ratios (Cho/NAA) on a voxel-by-voxel basis with abnormal activity defined as Cho/NAA ≥2. These images were compared on anatomically matched MRSI data collected after 3 weeks of RT. Changes in Cho/NAA between pretherapy and third-week RT scans were tested using Wilcoxon matched-pairs signed rank tests and correlated with progression-free survival, radiation dose and location of recurrence using Cox proportional hazards regression. After a median follow-up time of 8.6 months, 50% of patients had experienced progression based on imaging. Patients with a decreased or stable mean or median Cho/NAA values had less risk of progression (P<.01). Patients with an increase in mean or median Cho/NAA values at the third-week RT scan had a significantly greater chance of early progression (P<.01). An increased Cho/NAA at the third-week MRSI scan carried a hazard ratio of 2.72 (95% confidence interval, 1.10-6.71; P=.03). Most patients received the prescription dose of RT to the Cho/NAA ≥2 volume, where recurrence most often occurred. Change in mean and median Cho/NAA detected at 3 weeks was a significant predictor of early progression. The potential impact for risk

  16. Solar irradiance forecasting at one-minute intervals for different sky conditions using sky camera images

    Alonso-Montesinos, J.; Batlles, F.J.; Portillo, C.

    2015-01-01

    Highlights: • The solar resource has been predicted for three hours at 1-min intervals. • Digital image levels and cloud motion vectors are joint for irradiance forecasting. • The three radiation components have been predicted under different sky conditions. • Diffuse and global radiation has an nRMSE value around 10% in all sky conditions. • Beam irradiance is predicted with an nRMSE value of about 15% in overcast skies. - Abstract: In the search for new techniques to predict atmospheric features that might be useful to solar power plant operators, we have carried out solar irradiance forecasting using emerging sky camera technology. Digital image levels are converted into irradiances and then the maximum cross-correlation method is applied to obtain future predictions. This methodology is a step forward in the study of the solar resource, essential to solar plant operators in adapting a plant’s operating procedures to atmospheric conditions and to improve electricity generation. The results are set out using different statistical parameters, in which beam, diffuse and global irradiances give a constant normalized root-mean-square error value over the time interval for all sky conditions. The average measure is 25.44% for beam irradiance; 11.60% for diffuse irradiance and 11.17% for global irradiance.

  17. An Automated Algorithm for Identifying and Tracking Transverse Waves in Solar Images

    Weberg, Micah J.; Morton, Richard J.; McLaughlin, James A.

    2018-01-01

    Recent instrumentation has demonstrated that the solar atmosphere supports omnipresent transverse waves, which could play a key role in energizing the solar corona. Large-scale studies are required in order to build up an understanding of the general properties of these transverse waves. To help facilitate this, we present an automated algorithm for identifying and tracking features in solar images and extracting the wave properties of any observed transverse oscillations. We test and calibrate our algorithm using a set of synthetic data, which includes noise and rotational effects. The results indicate an accuracy of 1%–2% for displacement amplitudes and 4%–10% for wave periods and velocity amplitudes. We also apply the algorithm to data from the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory and find good agreement with previous studies. Of note, we find that 35%–41% of the observed plumes exhibit multiple wave signatures, which indicates either the superposition of waves or multiple independent wave packets observed at different times within a single structure. The automated methods described in this paper represent a significant improvement on the speed and quality of direct measurements of transverse waves within the solar atmosphere. This algorithm unlocks a wide range of statistical studies that were previously impractical.

  18. Fuzzy rule-based model for optimum orientation of solar panels using satellite image processing

    Zaher, A; Thiery, F; Grieu, S; Traoré, A; N’goran, Y

    2017-01-01

    In solar energy converting systems, a particular attention is paid to the orientation of solar collectors in order to optimize the overall system efficiency. In this context, the collectors can be fixed or oriented by a continuous solar tracking system. The proposed approach is based on METEOSAT images processing in order to detect the cloud coverage and its duration. These two parameters are treated by a fuzzy inference system deciding the optimal position of the solar panel. In fact, three weather cases can be considered: clear, partly covered or overcast sky. In the first case, the direct sunlight is more important than the diffuse radiation, thus the panel is always pointed towards the sun. In the overcast case, the solar beam is close to zero and the panel is placed horizontally to receive the diffuse radiation. Under partly covered conditions, the fuzzy inference system decides which of the previous positions is more efficient. The proposed approach is implemented using experimental prototype located in Perpignan (France). On a period of 17 months, the results are very satisfactory, with power gains of up to 23 % compared to the collectors oriented by a continuous solar tracking. (paper)

  19. 3D-MR Spectroscopic Imaging at 3Tesla for Early Response Assessment of Glioblastoma Patients during External Beam Radiation Therapy

    Muruganandham, Manickam; Clerkin, Patrick P; Smith, Brian J; Anderson, Carryn M; Morris, Ann; Capizzano, Aristides A; Magnotta, Vincent; McGuire, Sarah M; Smith, Mark C; Bayouth, John E; Buatti, John M

    2014-01-01

    Purpose To evaluate the utility of 3D-MR proton spectroscopic imaging for treatment planning and its implications for early response assessment in glioblastoma multiforme. Methods and Materials Eighteen patients with newly diagnosed, histologically confirmed glioblastoma had 3D-MR proton spectroscopic imaging (MRSI) along with T2 and T1 gadolinium enhanced MR images at simulation and at boost treatment planning after 17-20 fractions of radiotherapy. All patients received standard radiotherapy with temozolomide and follow-up with every two month MR scans. Progression free survival was defined using MacDonald criteria. MRSI images obtained at initial simulation were analyzed for choline / N-acetylaspartate ratios (Cho/NAA) on a voxel by voxel basis with abnormal activity defined as Cho/NAA ≥ 2. These images were compared on anatomically matched MRSI data collected after 3 weeks of radiotherapy. Changes in Cho/NAA between pre-therapy and 3rd week RT scans were tested using Wilcoxon matched-pairs signed rank tests and correlated with progression free survival, radiation dose and location of recurrence using Cox proportional hazards regression. Results After 8.6 months (median follow-up), 50% of patients had progressed based on imaging. Patients with a decreased or stable mean or median Cho/NAA values had less risk of progression (p< 0.01). Patients with an increase in mean or median Cho/NAA values at the 3rd week RT scan had a significantly greater chance of early progression (p <0.01). An increased Cho/NAA at the 3rd week MRSI scan carried a hazard ratio of 2.72 (95% confidence interval 1.10-6.71, p= 0.03). Most patients received the prescription dose of RT to the Cho/NAA ≥ 2 volume, which was where recurrence most often occurred. Conclusion Change in mean and median Cho/NAA detected at 3 weeks was a significant predictor of early progression. The potential impact for risk-adaptive therapy based on early spectroscopic findings is suggested. PMID:24986746

  20. Solar resources estimation combining digital terrain models and satellite images techniques

    Bosch, J.L.; Batlles, F.J. [Universidad de Almeria, Departamento de Fisica Aplicada, Ctra. Sacramento s/n, 04120-Almeria (Spain); Zarzalejo, L.F. [CIEMAT, Departamento de Energia, Madrid (Spain); Lopez, G. [EPS-Universidad de Huelva, Departamento de Ingenieria Electrica y Termica, Huelva (Spain)

    2010-12-15

    One of the most important steps to make use of any renewable energy is to perform an accurate estimation of the resource that has to be exploited. In the designing process of both active and passive solar energy systems, radiation data is required for the site, with proper spatial resolution. Generally, a radiometric stations network is used in this evaluation, but when they are too dispersed or not available for the study area, satellite images can be utilized as indirect solar radiation measurements. Although satellite images cover wide areas with a good acquisition frequency they usually have a poor spatial resolution limited by the size of the image pixel, and irradiation must be interpolated to evaluate solar irradiation at a sub-pixel scale. When pixels are located in flat and homogeneous areas, correlation of solar irradiation is relatively high, and classic interpolation can provide a good estimation. However, in complex topography zones, data interpolation is not adequate and the use of Digital Terrain Model (DTM) information can be helpful. In this work, daily solar irradiation is estimated for a wide mountainous area using a combination of Meteosat satellite images and a DTM, with the advantage of avoiding the necessity of ground measurements. This methodology utilizes a modified Heliosat-2 model, and applies for all sky conditions; it also introduces a horizon calculation of the DTM points and accounts for the effect of snow covers. Model performance has been evaluated against data measured in 12 radiometric stations, with results in terms of the Root Mean Square Error (RMSE) of 10%, and a Mean Bias Error (MBE) of +2%, both expressed as a percentage of the mean value measured. (author)

  1. High-resolution imaging of solar system objects

    Goldberg, B.A.

    1988-01-01

    The strategy of this investigation has been to develop new high-resolution imaging capabilities and to apply them to extended observing programs. These programs have included Io's neutral sodium cloud and comets. The Io observing program was carried out at Table Mountain Observatory (1976 to 1981), providing a framework interpreting Voyager measurements of the Io torus, and serving as an important reference for studying asymmetries and time variabilities in the Jovian magnetosphere. Comet observations made with the 3.6 m Canada-France-Hawaii Telescope and 1.6 m AMOS telescope (1984 to 1987) provide basis for studying early coma development in Halley, the kinematics of its nucleus, and the internal and external structure of the nucleus. Images of GZ from the ICE encounter period form the basis for unique comparisons with in situ magnetic field and dust impact measurements to determine the ion tail and dust coma structure, respectively

  2. Prior-knowledge Fitting of Accelerated Five-dimensional Echo Planar J-resolved Spectroscopic Imaging: Effect of Nonlinear Reconstruction on Quantitation.

    Iqbal, Zohaib; Wilson, Neil E; Thomas, M Albert

    2017-07-24

    1 H Magnetic Resonance Spectroscopic imaging (SI) is a powerful tool capable of investigating metabolism in vivo from mul- tiple regions. However, SI techniques are time consuming, and are therefore difficult to implement clinically. By applying non-uniform sampling (NUS) and compressed sensing (CS) reconstruction, it is possible to accelerate these scans while re- taining key spectral information. One recently developed method that utilizes this type of acceleration is the five-dimensional echo planar J-resolved spectroscopic imaging (5D EP-JRESI) sequence, which is capable of obtaining two-dimensional (2D) spectra from three spatial dimensions. The prior-knowledge fitting (ProFit) algorithm is typically used to quantify 2D spectra in vivo, however the effects of NUS and CS reconstruction on the quantitation results are unknown. This study utilized a simulated brain phantom to investigate the errors introduced through the acceleration methods. Errors (normalized root mean square error >15%) were found between metabolite concentrations after twelve-fold acceleration for several low concentra- tion (OGM) human brain matter were quantified in vivo using the 5D EP-JRESI sequence with eight-fold acceleration.

  3. Evaluating the spatio-temporal performance of sky imager based solar irradiance analysis and forecasts

    Schmidt, T.; Kalisch, J.; Lorenz, E.; Heinemann, D.

    2015-10-01

    Clouds are the dominant source of variability in surface solar radiation and uncertainty in its prediction. However, the increasing share of solar energy in the world-wide electric power supply increases the need for accurate solar radiation forecasts. In this work, we present results of a shortest-term global horizontal irradiance (GHI) forecast experiment based on hemispheric sky images. A two month dataset with images from one sky imager and high resolutive GHI measurements from 99 pyranometers distributed over 10 km by 12 km is used for validation. We developed a multi-step model and processed GHI forecasts up to 25 min with an update interval of 15 s. A cloud type classification is used to separate the time series in different cloud scenarios. Overall, the sky imager based forecasts do not outperform the reference persistence forecasts. Nevertheless, we find that analysis and forecast performance depend strongly on the predominant cloud conditions. Especially convective type clouds lead to high temporal and spatial GHI variability. For cumulus cloud conditions, the analysis error is found to be lower than that introduced by a single pyranometer if it is used representatively for the whole area in distances from the camera larger than 1-2 km. Moreover, forecast skill is much higher for these conditions compared to overcast or clear sky situations causing low GHI variability which is easier to predict by persistence. In order to generalize the cloud-induced forecast error, we identify a variability threshold indicating conditions with positive forecast skill.

  4. Uniform and non-uniform modes of nanosecond-pulsed dielectric barrier discharge in atmospheric air: fast imaging and spectroscopic measurements of electric fields

    Liu, Chong; Dobrynin, Danil; Fridman, Alexander

    2014-01-01

    In this study, we report experimental results on fast intensified charge-coupled device (ICCD) imaging of the development of nanosecond-pulsed dielectric barrier discharge (DBD) in atmospheric air and spectroscopic measurements of the electric field in the discharge. The uniformity of the discharge images obtained with nanosecond exposure times was analysed using chi-square test. The results indicate that DBD uniformity strongly depends on the applied (global) electric field in the discharge gap, which is a threshold phenomenon. We show that in the case of strong overvoltage on the discharge gap (provided by fast rise times), there is a transition from filamentary to uniform DBD mode that correlates to the corresponding decrease of the maximum local electric field in the discharge. (fast track communication)

  5. Uniform and non-uniform modes of nanosecond-pulsed dielectric barrier discharge in atmospheric air: fast imaging and spectroscopic measurements of electric field

    Liu, Chong; Dobrynin, Danil; Fridman, Alexander

    2014-01-01

    In this study, we report experimental results on fast ICCD imaging of development of nanosecond-pulsed dielectric barrier discharge (DBD) in atmospheric air and spectroscopic measurements of electric field in the discharge. Uniformity of the discharge images obtained with nanosecond exposure times were analyzed using chi-square test. The results indicate that DBD uniformity strongly depends on applied (global) electric field in the discharge gap, and is a threshold phenomenon. We show that in the case of strong overvoltage on the discharge gap (provided by fast rise times), there is transition from filamentary to uniform DBD mode which correlates to the corresponding decrease of maximum local electric field in the discharge. PMID:25071294

  6. Acute putaminal necrosis and white matter demyelination in a child with subnormal copper metabolism in Wilson disease: MR imaging and spectroscopic findings

    Juan, Chun-Jung; Chung, Hsiao-Wen; Chen, Cheng-Yu.; Chin, Shy-Chy; Hsueh, Chun-Jen; Liu, Yi-Jui; Chu, Hsin; Zimmerman, Robert A.

    2005-01-01

    Wilson disease (WD) that manifests solely with acute and severe neurological damage in the absence of hepatic disease and Kayser-Fleischer ring of the cornea is rare and difficult to diagnose at the acute setting. This report describes unusual diffusion and proton spectroscopic magnetic resonance (MR) imaging findings in a 12-year-old boy with WD who presented with hemichorea and subnormal copper metabolism. The MR imaging findings of lactate accumulation, decrease of N-acerylaspartate/creatinine (NAA/Cr) ratio and markedly increased apparent diffusion coefficient (ADC) value of the asymmetrical edematous putaminal lesions in the early stage were suggestive of acute necrosis with anaerobic metabolism of glucose leading to poor clinical outcome at follow-up. (orig.)

  7. Acute putaminal necrosis and white matter demyelination in a child with subnormal copper metabolism in Wilson disease: MR imaging and spectroscopic findings

    Juan, Chun-Jung; Chung, Hsiao-Wen [National Taiwan University, Department of Electrical Engineering, Taipei (Taiwan); Tri-Service General Hospital, Department of Radiology, Taipei (Taiwan); Chen, Cheng-Yu.; Chin, Shy-Chy; Hsueh, Chun-Jen [Tri-Service General Hospital, Department of Radiology, Taipei (Taiwan); Liu, Yi-Jui [Feng Chia University, Department of Automatic Control Engineering, Taichung (Taiwan); Chu, Hsin [National Defense Medical Center, Department of Neurology, Taipei (Taiwan); Zimmerman, Robert A. [Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, Pennsylvania (United States)

    2005-06-01

    Wilson disease (WD) that manifests solely with acute and severe neurological damage in the absence of hepatic disease and Kayser-Fleischer ring of the cornea is rare and difficult to diagnose at the acute setting. This report describes unusual diffusion and proton spectroscopic magnetic resonance (MR) imaging findings in a 12-year-old boy with WD who presented with hemichorea and subnormal copper metabolism. The MR imaging findings of lactate accumulation, decrease of N-acerylaspartate/creatinine (NAA/Cr) ratio and markedly increased apparent diffusion coefficient (ADC) value of the asymmetrical edematous putaminal lesions in the early stage were suggestive of acute necrosis with anaerobic metabolism of glucose leading to poor clinical outcome at follow-up. (orig.)

  8. In vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI): [3,4-(13)CH(2)]glutamate/glutamine tomography in rat brain.

    Hyder, F; Renken, R; Rothman, D L

    1999-12-01

    A method for in vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI) is described. This method is composed of an echo-planar based acquisition implemented with (13)C-(1)H J editing spectroscopy and is intended for high temporal and spatial resolution in vivo spectroscopic imaging of (13)C turnover, from D-[1,6-(13)C]glucose to glutamate and glutamine, in the brain. At a static magnetic field strength of 7 T, both in vitro and in vivo chemical shift imaging data are presented with a spatial resolution of 8 microL (i.e., 1.25 x 1.25 x 5.00 mm(3)) and a maximum spectral bandwidth of 5.2 ppm in (1)H. Chemical shift imaging data acquired every 11 minutes allowed detection of regional [4-(13)CH(2)]glutamate turnover in rat brain. The [4-(13)CH(2)]glutamate turnover curves, which can be converted to tricarboxylic acid cycle fluxes, showed that the tricarboxylic acid cycle flux (V(TCA)) in pure gray and white matter can range from 1.2 +/- 0.2 to 0.5 +/- 0.1 micromol/g/min, respectively, for morphine-anesthetized rats. The mean cortical V(TCA) from 32 voxels of 1.0 +/- 0.3 micromol/g/min (N = 3) is in excellent agreement with previous localized measurements that have demonstrated that V(TCA) can range from 0.9-1.1 micromol/g/min under identical anesthetized conditions. Magn Reson Med 42:997-1003, 1999. Copyright 1999 Wiley-Liss, Inc.

  9. Correcting the effect of refraction and dispersion of light in FT-IR spectroscopic imaging in transmission through thick infrared windows.

    Chan, K L Andrew; Kazarian, Sergei G

    2013-01-15

    Transmission mode is one of the most common sampling methods for FT-IR spectroscopic imaging because the spectra obtained generally have a reasonable signal-to-noise ratio. However, dispersion and refraction of infrared light occurs when samples are sandwiched between infrared windows or placed underneath a layer of liquid. Dispersion and refraction cause infrared light to focus with different focal lengths depending on the wavelength (wavenumber) of the light. As a result, images obtained are in focus only at a particular wavenumber while they are defocused at other wavenumber values. In this work, a solution to correct this spread of focus by means of adding a lens on top of the infrared transparent window, such that a pseudo hemisphere is formed, has been investigated. Through this lens (or pseudo hemisphere), refraction of light is removed and the light across the spectral range has the same focal depth. Furthermore, the lens acts as a solid immersion objective and an increase of both magnification and spatial resolution (by 1.4 times) is demonstrated. The spatial resolution was investigated using an USAF resolution target, showing that the Rayleigh criterion can be achieved, as well as a sample with a sharp polymer interface to indicate the spatial resolution that can be expected in real samples. The reported approach was used to obtain chemical images of cross sections of cancer tissue and hair samples sandwiched between infrared windows showing the versatility and applicability of the method. In addition to the improved spatial resolution, the results reported herein also demonstrate that the lens can reduce the effect of scattering near the edges of tissue samples. The advantages of the presented approach, obtaining FT-IR spectroscopic images in transmission mode with the same focus across all wavenumber values and simultaneous improvement in spatial resolution, will have wide implications ranging from studies of live cells to sorption of drugs into tissues.

  10. Short-Term Solar Irradiance Forecasts Using Sky Images and Radiative Transfer Model

    Juan Du

    2018-05-01

    Full Text Available In this paper, we propose a novel forecast method which addresses the difficulty in short-term solar irradiance forecasting that arises due to rapidly evolving environmental factors over short time periods. This involves the forecasting of Global Horizontal Irradiance (GHI that combines prediction sky images with a Radiative Transfer Model (RTM. The prediction images (up to 10 min ahead are produced by a non-local optical flow method, which is used to calculate the cloud motion for each pixel, with consecutive sky images at 1 min intervals. The Direct Normal Irradiance (DNI and the diffuse radiation intensity field under clear sky and overcast conditions obtained from the RTM are then mapped to the sky images. Through combining the cloud locations on the prediction image with the corresponding instance of image-based DNI and diffuse radiation intensity fields, the GHI can be quantitatively forecasted for time horizons of 1–10 min ahead. The solar forecasts are evaluated in terms of root mean square error (RMSE and mean absolute error (MAE in relation to in-situ measurements and compared to the performance of the persistence model. The results of our experiment show that GHI forecasts using the proposed method perform better than the persistence model.

  11. Automated Solar Flare Detection and Feature Extraction in High-Resolution and Full-Disk Hα Images

    Yang, Meng; Tian, Yu; Liu, Yangyi; Rao, Changhui

    2018-05-01

    In this article, an automated solar flare detection method applied to both full-disk and local high-resolution Hα images is proposed. An adaptive gray threshold and an area threshold are used to segment the flare region. Features of each detected flare event are extracted, e.g. the start, peak, and end time, the importance class, and the brightness class. Experimental results have verified that the proposed method can obtain more stable and accurate segmentation results than previous works on full-disk images from Big Bear Solar Observatory (BBSO) and Kanzelhöhe Observatory for Solar and Environmental Research (KSO), and satisfying segmentation results on high-resolution images from the Goode Solar Telescope (GST). Moreover, the extracted flare features correlate well with the data given by KSO. The method may be able to implement a more complicated statistical analysis of Hα solar flares.

  12. Reconstruction of the solar EUV irradiance from 1996 to 2010 based on SOHO/EIT images

    Haberreiter Margit

    2014-01-01

    Full Text Available The solar Extreme UltraViolet (EUV spectrum has important effects on the Earth’s upper atmosphere. For a detailed investigation of these effects it is important to have a consistent data series of the EUV spectral irradiance available. We present a reconstruction of the solar EUV irradiance based on SOHO/EIT images, along with synthetic spectra calculated using different coronal features which represent the brightness variation of the solar atmosphere. The EIT images are segmented with the SPoCA2 tool which separates the features based on a fixed brightness classification scheme. With the SOLMOD code we then calculate intensity spectra for the 10–100 nm wavelength range and each of the coronal features. Weighting the intensity spectra with the area covered by each of the features yields the temporal variation of the EUV spectrum. The reconstructed spectrum is then validated against the spectral irradiance as observed with SOHO/SEM. Our approach leads to good agreement between the reconstructed and the observed spectral irradiance. This study is an important step toward understanding variations in the solar EUV spectrum and ultimately its effect on the Earth’s upper atmosphere.

  13. Fully automated atlas-based method for prescribing 3D PRESS MR spectroscopic imaging: Toward robust and reproducible metabolite measurements in human brain.

    Bian, Wei; Li, Yan; Crane, Jason C; Nelson, Sarah J

    2018-02-01

    To implement a fully automated atlas-based method for prescribing 3D PRESS MR spectroscopic imaging (MRSI). The PRESS selected volume and outer-volume suppression bands were predefined on the MNI152 standard template image. The template image was aligned to the subject T 1 -weighted image during a scan, and the resulting transformation was then applied to the predefined prescription. To evaluate the method, H-1 MRSI data were obtained in repeat scan sessions from 20 healthy volunteers. In each session, datasets were acquired twice without repositioning. The overlap ratio of the prescribed volume in the two sessions was calculated and the reproducibility of inter- and intrasession metabolite peak height and area ratios was measured by the coefficient of variation (CoV). The CoVs from intra- and intersession were compared by a paired t-test. The average overlap ratio of the automatically prescribed selection volumes between two sessions was 97.8%. The average voxel-based intersession CoVs were less than 0.124 and 0.163 for peak height and area ratios, respectively. Paired t-test showed no significant difference between the intra- and intersession CoVs. The proposed method provides a time efficient method to prescribe 3D PRESS MRSI with reproducible imaging positioning and metabolite measurements. Magn Reson Med 79:636-642, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  14. Exquisite Nova Light Curves from the Solar Mass Ejection Imager (SMEI)

    Hounsell, R.; Bode, M. F.; Hick, P. P.; Buffington, A.; Jackson, B. V.; Clover, J. M.; Shafter, A. W.; Darnley, M. J.; Mawson, N. R.; Steele, I. A.; Evans, A.; Eyres, S. P. S.; O'Brien, T. J.

    2010-01-01

    We present light curves of three classical novae (KT Eridani, V598 Puppis, V1280 Scorpii) and one recurrent nova (RS Ophiuchi) derived from data obtained by the Solar Mass Ejection Imager (SMEI) on board the Coriolis satellite. SMEI provides near complete sky-map coverage with precision visible-light photometry at 102-minute cadence. The light curves derived from these sky maps offer unprecedented temporal resolution around, and especially before, maximum light, a phase of the nova eruption n...

  15. The spectrometer/telescope for imaging X-rays on board the ESA Solar Orbiter spacecraft

    Krucker, S.; Benz, A.O.; Hurford, G.J.; Arnold, N.G.; Orleański, P.; Gröbelbauer, H.-P.; Casadei, D.; Kobler, S.; Iseli, L.; Wiehl, H.J.; Csillaghy, A.; Etesi, L.; Hochmuth, N.; Battaglia, M.; Bednarzik, M.; Resanovic, R.; Grimm, O.; Viertel, G.; Commichau, V.; Howard, A.

    2013-01-01

    Solar Orbiter is a Sun-observing mission led by the European Space Agency, addressing the interaction between the Sun and the heliosphere. It will carry ten instruments, among them the X-ray imaging spectrometer STIX. STIX will determine the intensity, spectrum, timing, and location of thermal and accelerated electrons near the Sun through their bremsstrahlung X-ray emission. This report gives a brief overview of the STIX scientific goals and covers in more detail the instrument design and challenges

  16. MuSICa image slicer prototype at 1.5-m GREGOR solar telescope

    Calcines, A.; López, R. L.; Collados, M.; Vega Reyes, N.

    2014-07-01

    Integral Field Spectroscopy is an innovative technique that is being implemented in the state-of-the-art instruments of the largest night-time telescopes, however, it is still a novelty for solar instrumentation. A new concept of image slicer, called MuSICa (Multi-Slit Image slicer based on collimator-Camera), has been designed for the integral field spectrograph of the 4-m European Solar Telescope. This communication presents an image slicer prototype of MuSICa for GRIS, the spectrograph of the 1.5-m GREGOR solar telescope located at the Observatory of El Teide. MuSICa at GRIS reorganizes a 2-D field of view of 24.5 arcsec into a slit of 0.367 arcsec width by 66.76 arcsec length distributed horizontally. It will operate together with the TIP-II polarimeter to offer high resolution integral field spectropolarimetry. It will also have a bidimensional field of view scanning system to cover a field of view up to 1 by 1 arcmin.

  17. New technology to collect solar energy: non-imaging focusing heliostat

    Kok Keong Chong; Bahrom Sanugi; Chen, L.C.; Jasmy Yunus; Kannan, K.S.; Lim, B.H.; Lim, C.S.; Noriah Bidin; Omar Aliman; Sahar Salehan; Shaikh Ab Rezan; Tam, C.M.; Tan, K.K.; Chen, Y.T.

    2001-01-01

    In this paper, we report a non-imaging focusing heliostat with multi-faceted plane mirrors for the effective use of solar energy. The non-imaging heliostat demonstrates a new technology to track the sun radiation and then concentrating it onto a stationary receiver by a mere single reflection. Deviated from the conventional method, one of the rotation axes is reoriented in a way that can significantly reduce the number of motors. The feasibility of the new scheme has been proved by a 25-mirrors-heliostat in Universiti Technologi Malaysia (UTM) campus. (Author)

  18. Multi-slice echo-planar spectroscopic MR imaging provides both global and local metabolite measures in multiple sclerosis

    Mathiesen, Henrik Kahr; Tscherning, Thomas; Sorensen, Per Soelberg

    2005-01-01

    MR spectroscopy (MRS) provides information about neuronal loss or dysfunction by measuring decreases in N-acetyl aspartate (NAA), a metabolite widely believed to be a marker of neuronal viability. In multiple sclerosis (MS), whole-brain NAA (WBNAA) has been suggested as a marker of disease...... progression and treatment efficacy in treatment trials, and the ability to measure NAA loss in specific brain regions early in the evolution of this disease may have prognostic value. Most spectroscopic studies to date have been limited to single voxels or nonlocalized measurements of WBNAA only...

  19. The Focusing Optics X-ray Solar Imager Small Explorer Concept Mission

    Christe, Steven; Shih, Albert Y.; Dennis, Brian R.; Glesener, Lindsay; Krucker, Sam; Saint-Hilaire, Pascal; Gubarev, Mikhail; Ramsey, Brian

    2016-05-01

    We present the FOXSI (Focusing Optics X-ray Solar Imager) small explorer (SMEX) concept, a mission dedicated to studying particle acceleration and energy release on the Sun. FOXSI is designed as a 3-axis stabilized spacecraft in low-Earth orbit making use of state-of-the-art grazing incidence focusing optics combined withpixelated solid-state detectors, allowing for direct imaging of solar X-rays. The current design being studied features multiple telescopes with a 14 meter focal length enabled by a deployable boom.FOXSI will observe the Sun in the 3-100 keV energy range. The FOXSI imaging concept has already been tested on two sounding rocket flights, in 2012 and 2014 and on the HEROES balloon payload flight in 2013. FOXSI will image the Sun with an angular resolution of 5'', a spectral resolution of 0.5 keV, and sub-second temporal resolution. FOXSI is a direct imaging spectrometer with high dynamic range and sensitivity and will provide a brand-new perspective on energy release on the Sun. We describe the mission and its science objectives.

  20. Image motion compensation on the Spacelab 2 Solar Optical Universal Polarimeter /SL2 SOUP/

    Tarbell, T. D.; Duncan, D. W.; Finch, M. L.; Spence, G.

    1981-01-01

    The SOUP experiment on Spacelab 2 includes a 30 cm visible light telescope and focal plane package mounted on the Instrument Pointing System (IPS). Scientific goals of the experiment dictate pointing stability requirements of less than 0.05 arcsecond jitter over periods of 5-20 seconds. Quantitative derivations of these requirements from two different aspects are presented: (1) avoidance of motion blurring of diffraction-limited images; (2) precise coalignment of consecutive frames to allow measurement of small image differences. To achieve this stability, a fine guider system capable of removing residual jitter of the IPS and image motions generated on the IPS cruciform instrument support structure has been constructed. This system uses solar limb detectors in the prime focal plane to derive an error signal. Image motion due to pointing errors is compensated by the agile secondary mirror mounted on piezoelectric transducers, controlled by a closed-loop servo system.

  1. Recent Advances and Applications of External Cavity-QCLs towards Hyperspectral Imaging for Standoff Detection and Real-Time Spectroscopic Sensing of Chemicals

    Ralf Ostendorf

    2016-05-01

    Full Text Available External-cavity quantum cascade lasers (EC-QCL are now established as versatile wavelength-tunable light sources for analytical spectroscopy in the mid-infrared (MIR spectral range. We report on the realization of rapid broadband spectral tuning with kHz scan rates by combining a QCL chip with a broad gain spectrum and a resonantly driven micro-opto-electro-mechanical (MOEMS scanner with an integrated diffraction grating in Littrow configuration. The capability for real-time spectroscopic sensing based on MOEMS EC-QCLs is demonstrated by transmission measurements performed on polystyrene reference absorber sheets, as well as on hazardous substances, such as explosives. Furthermore, different applications for the EC-QCL technology in spectroscopic sensing are presented. These include the fields of process analysis with on- or even inline capability and imaging backscattering spectroscopy for contactless identification of solid and liquid contaminations on surfaces. Recent progress in trace detection of explosives and related precursors in relevant environments as well as advances in food quality monitoring by discriminating fresh and mold contaminated peanuts based on their MIR backscattering spectrum is shown.

  2. Early solar physics

    Meadows, A J

    1970-01-01

    Early Solar Physics reviews developments in solar physics, particularly the advent of solar spectroscopy and the discovery of relationships between the various layers of the solar atmosphere and between the different forms of solar activity. Topics covered include solar observations during 1843; chemical analysis of the solar atmosphere; the spectrum of a solar prominence; and the solar eclipse of December 12, 1871. Spectroscopic observations of the sun are also presented. This book is comprised of 30 chapters and begins with an overview of ideas about the sun in the mid-nineteenth century, fo

  3. Simultaneous PET/MRI with 13C magnetic resonance spectroscopic imaging (hyperPET): phantom-based evaluation of PET quantification

    Hansen, Adam E.; Andersen, Flemming L.; Henriksen, Sarah T.

    2016-01-01

    Background: Integrated PET/MRI with hyperpolarized 13C magnetic resonance spectroscopic imaging (13C-MRSI) offers simultaneous, dual-modality metabolic imaging. A prerequisite for the use of simultaneous imaging is the absence of interference between the two modalities. This has been documented...... for a clinical whole-body system using simultaneous 1 H-MRI and PET but never for 13C-MRSI and PET. Here, the feasibility of simultaneous PET and 13C-MRSI as well as hyperpolarized 13C-MRSI in an integrated whole-body PET/MRI hybrid scanner is evaluated using phantom experiments. Methods: Combined PET and 13C......-MRSI phantoms including a NEMA [18F]-FDG phantom, 13C-acetate and 13C-urea sources, and hyperpolarized 13C-pyruvate were imaged repeatedly with PET and/or 13C-MRSI. Measurements evaluated for interference effects included PET activity values in the largest sphere and a background region; total number of PET...

  4. Initial results of 3-dimensional 1H-magnetic resonance spectroscopic imaging in the localization of prostate cancer at 3 Tesla: should we use an endorectal coil?

    Yakar, Derya; Heijmink, Stijn W T P J; Hulsbergen-van de Kaa, Christina A; Huisman, Henkjan; Barentsz, Jelle O; Fütterer, Jurgen J; Scheenen, Tom W J

    2011-05-01

    The purpose of this study was to compare the diagnostic performance of 3 Tesla, 3-dimensional (3D) magnetic resonance spectroscopic imaging (MRSI) in the localization of prostate cancer (PCa) with and without the use of an endorectal coil (ERC). Our prospective study was approved by the institutional review board, and written informed consent was obtained from all patients. Between October 2004 and January 2006, 18 patients with histologically proven PCa on biopsy and scheduled for radical prostatectomy were included and underwent 3D-MRSI with and without an ERC. The prostate was divided into 14 regions of interest (ROIs). Four readers independently rated (on a 5-point scale) their confidence that cancer was present in each of these ROIs. These findings were correlated with whole-mount prostatectomy specimens. Areas under the receiver-operating characteristic curve were determined. A difference with a P Tesla slightly but significantly increased the localization performance compared with not using an ERC.

  5. Proton Magnetic Resonance Spectroscopic Imaging in Newly Diagnosed Glioblastoma: Predictive Value for the Site of Postradiotherapy Relapse in a Prospective Longitudinal Study

    Laprie, Anne; Catalaa, Isabelle; Cassol, Emmanuelle; McKnight, Tracy R.; Berchery, Delphine; Marre, Delphine; Bachaud, Jean-Marc; Berry, Isabelle; Moyal, Elizabeth Cohen-Jonathan

    2008-01-01

    Purpose: To investigate the association between magnetic resonance spectroscopic imaging (MRSI)-defined, metabolically abnormal tumor regions and subsequent sites of relapse in data from patients treated with radiotherapy (RT) in a prospective clinical trial. Methods and Materials: Twenty-three examinations were performed prospectively for 9 patients with newly diagnosed glioblastoma multiforme studied in a Phase I trial combining Tipifarnib and RT. The patients underwent magnetic resonance imaging (MRI) and MRSI before treatment and every 2 months until relapse. The MRSI data were categorized by the choline (Cho)/N-acetyl-aspartate (NAA) ratio (CNR) as a measure of spectroscopic abnormality. CNRs corresponding to T1 and T2 MRI for 1,207 voxels were evaluated before RT and at recurrence. Results: Before treatment, areas of CNR2 (CNR ≥2) represented 25% of the contrast-enhancing (T1CE) regions and 10% of abnormal T2 regions outside T1CE (HyperT2). The presence of CNR2 was often an early indicator of the site of relapse after therapy. In fact, 75% of the voxels within the T1CE+CNR2 before therapy continued to exhibit CNR2 at relapse, compared with 22% of the voxels within the T1CE with normal CNR (p < 0.05). The location of new contrast enhancement with CNR2 corresponded in 80% of the initial HyperT2+CNR2 vs. 20.7% of the HyperT2 voxels with normal CNR (p < 0.05). Conclusion: Metabolically active regions represented a small percentage of pretreatment MRI abnormalities and were predictive for the site of post-RT relapse. The incorporation of MRSI data in the definition of RT target volumes for selective boosting may be a promising avenue leading to increased local control of glioblastomas

  6. Viewing and imaging the solar system a guide for amateur astronomers

    Clark, Jane

    2015-01-01

    Viewing and Imaging the Solar System: A Guide for Amateur Astronomers is for those who want to develop their ability to observe and image Solar System objects, including the planets and moons, the Sun, and comets and asteroids. They might be beginners, or they may have already owned and used an astronomical telescope for a year or more. Newcomers are almost always wowed by sights such as the rings of Saturn and the moons of Jupiter, but have little idea how to find these objects for themselves (with the obvious exceptions of the Sun and Moon). They also need guidance about what equipment to use, besides a telescope. This book is written by an expert on the Solar System, who has had a lot of experience with outreach programs, which teach others how to make the most of relatively simple and low-cost equipment. That does not mean that this book is not for serious amateurs. On the contrary, it is designed to show amateur astronomers, in a relatively light-hearted—and math-free way—how to become serious.

  7. Evaluating the spatio-temporal performance of sky-imager-based solar irradiance analysis and forecasts

    Schmidt, Thomas; Kalisch, John; Lorenz, Elke; Heinemann, Detlev

    2016-03-01

    Clouds are the dominant source of small-scale variability in surface solar radiation and uncertainty in its prediction. However, the increasing share of solar energy in the worldwide electric power supply increases the need for accurate solar radiation forecasts. In this work, we present results of a very short term global horizontal irradiance (GHI) forecast experiment based on hemispheric sky images. A 2-month data set with images from one sky imager and high-resolution GHI measurements from 99 pyranometers distributed over 10 km by 12 km is used for validation. We developed a multi-step model and processed GHI forecasts up to 25 min with an update interval of 15 s. A cloud type classification is used to separate the time series into different cloud scenarios. Overall, the sky-imager-based forecasts do not outperform the reference persistence forecasts. Nevertheless, we find that analysis and forecast performance depends strongly on the predominant cloud conditions. Especially convective type clouds lead to high temporal and spatial GHI variability. For cumulus cloud conditions, the analysis error is found to be lower than that introduced by a single pyranometer if it is used representatively for the whole area in distances from the camera larger than 1-2 km. Moreover, forecast skill is much higher for these conditions compared to overcast or clear sky situations causing low GHI variability, which is easier to predict by persistence. In order to generalize the cloud-induced forecast error, we identify a variability threshold indicating conditions with positive forecast skill.

  8. Evaluating the spatio-temporal performance of sky-imager-based solar irradiance analysis and forecasts

    T. Schmidt

    2016-03-01

    Full Text Available Clouds are the dominant source of small-scale variability in surface solar radiation and uncertainty in its prediction. However, the increasing share of solar energy in the worldwide electric power supply increases the need for accurate solar radiation forecasts. In this work, we present results of a very short term global horizontal irradiance (GHI forecast experiment based on hemispheric sky images. A 2-month data set with images from one sky imager and high-resolution GHI measurements from 99 pyranometers distributed over 10 km by 12 km is used for validation. We developed a multi-step model and processed GHI forecasts up to 25 min with an update interval of 15 s. A cloud type classification is used to separate the time series into different cloud scenarios. Overall, the sky-imager-based forecasts do not outperform the reference persistence forecasts. Nevertheless, we find that analysis and forecast performance depends strongly on the predominant cloud conditions. Especially convective type clouds lead to high temporal and spatial GHI variability. For cumulus cloud conditions, the analysis error is found to be lower than that introduced by a single pyranometer if it is used representatively for the whole area in distances from the camera larger than 1–2 km. Moreover, forecast skill is much higher for these conditions compared to overcast or clear sky situations causing low GHI variability, which is easier to predict by persistence. In order to generalize the cloud-induced forecast error, we identify a variability threshold indicating conditions with positive forecast skill.

  9. DEEP HST /STIS VISIBLE-LIGHT IMAGING OF DEBRIS SYSTEMS AROUND SOLAR ANALOG HOSTS

    Schneider, Glenn; Gaspar, Andras [Steward Observatory and the Department of Astronomy, The University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States); Grady, Carol A. [Eureka Scientific, 2452 Delmer, Suite 100, Oakland, CA 96002 (United States); Stark, Christopher C.; Kuchner, Marc J. [NASA/Goddard Space Flight Center, Exoplanets and Stellar Astrophysics Laboratory, Code 667, Greenbelt, MD 20771 (United States); Carson, Joseph [Department of Physics and Astronomy, College of Charleston, 66 George Street, Charleston, SC 29424 (United States); Debes, John H.; Hines, Dean C.; Perrin, Marshall [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Henning, Thomas [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117, Heidelberg (Germany); Jang-Condell, Hannah [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82071 (United States); Rodigas, Timothy J. [Department of Terrestrial Magnetism, Carnegie Institute of Washington, 5241 Branch Road, NW, Washington, DC 20015 (United States); Tamura, Motohide [The University of Tokyo, National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan); Wisniewski, John P., E-mail: gschneider@as.arizona.edu [H. L. Dodge Department of Physics and Astronomy, University of Oklahoma, 440 West Brooks Street, Norman, OK 73019 (United States)

    2016-09-01

    We present new Hubble Space Telescope observations of three a priori known starlight-scattering circumstellar debris systems (CDSs) viewed at intermediate inclinations around nearby close-solar analog stars: HD 207129, HD 202628, and HD 202917. Each of these CDSs possesses ring-like components that are more massive analogs of our solar system's Edgeworth–Kuiper Belt. These systems were chosen for follow-up observations to provide imaging with higher fidelity and better sensitivity for the sparse sample of solar-analog CDSs that range over two decades in systemic ages, with HD 202628 and HD 207129 (both ∼2.3 Gyr) currently the oldest CDSs imaged in visible or near-IR light. These deep (10–14 ks) observations, made with six-roll point-spread-function template visible-light coronagraphy using the Space Telescope Imaging Spectrograph, were designed to better reveal their angularly large debris rings of diffuse/low surface brightness, and for all targets probe their exo-ring environments for starlight-scattering materials that present observational challenges for current ground-based facilities and instruments. Contemporaneously also observing with a narrower occulter position, these observations additionally probe the CDS endo-ring environments that are seen to be relatively devoid of scatterers. We discuss the morphological, geometrical, and photometric properties of these CDSs also in the context of other CDSs hosted by FGK stars that we have previously imaged as a homogeneously observed ensemble. From this combined sample we report a general decay in quiescent-disk F {sub disk}/ F {sub star} optical brightness ∼ t {sup −0.8}, similar to what is seen at thermal IR wavelengths, and CDSs with a significant diversity in scattering phase asymmetries, and spatial distributions of their starlight-scattering grains.

  10. In vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI) : [3,4-(CH2)-C-13] glutamate/glutamine tomography in rat brain

    Hyder, F; Renken, R; Rothman, DL

    1999-01-01

    A method for in vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI) is described. This method is composed of an echo-planar based acquisition implemented with C-13-H-1 J editing spectroscopy and is intended for high temporal and spatial resolution in vivo

  11. Extreme Ultraviolet Solar Images Televised In-Flight with a Rocket-Borne SEC Vidicon System.

    Tousey, R; Limansky, I

    1972-05-01

    A TV image of the entire sun while an importance 2N solar flare was in progress was recorded in the extreme ultraviolet (XUV) radiation band 171-630 A and transmitted to ground from an Aerobee-150 rocket on 4 November 1969 using S-band telemetry. The camera tube was a Westinghouse Electric Corporation SEC vidicon, with its fiber optic faceplate coated with an XUV to visible conversion layer of p-quaterphenyl. The XUV passband was produced by three 1000-A thick aluminum filters in series together with the platinized reflecting surface of the off-axis paraboloid that imaged the sun. A number of images were recorded with integration times between 1/30 see and 2 sec. Reconstruction of pictures was enhanced by combining several to reduce the noise.

  12. Imaging of the CO snow line in a solar nebula analog.

    Qi, Chunhua; Öberg, Karin I; Wilner, David J; D'Alessio, Paola; Bergin, Edwin; Andrews, Sean M; Blake, Geoffrey A; Hogerheijde, Michiel R; van Dishoeck, Ewine F

    2013-08-09

    Planets form in the disks around young stars. Their formation efficiency and composition are intimately linked to the protoplanetary disk locations of "snow lines" of abundant volatiles. We present chemical imaging of the carbon monoxide (CO) snow line in the disk around TW Hya, an analog of the solar nebula, using high spatial and spectral resolution Atacama Large Millimeter/Submillimeter Array observations of diazenylium (N2H(+)), a reactive ion present in large abundance only where CO is frozen out. The N2H(+) emission is distributed in a large ring, with an inner radius that matches CO snow line model predictions. The extracted CO snow line radius of ~30 astronomical units helps to assess models of the formation dynamics of the solar system, when combined with measurements of the bulk composition of planets and comets.

  13. High resolution laser beam induced current images under trichromatic laser radiation: approximation to the solar irradiation.

    Navas, F J; Alcántara, R; Fernández-Lorenzo, C; Martín-Calleja, J

    2010-03-01

    A laser beam induced current (LBIC) map of a photoactive surface is a very useful tool when it is necessary to study the spatial variability of properties such as photoconverter efficiency or factors connected with the recombination of carriers. Obtaining high spatial resolution LBIC maps involves irradiating the photoactive surface with a photonic beam with Gaussian power distribution and with a low dispersion coefficient. Laser emission fulfils these characteristics, but against it is the fact that it is highly monochromatic and therefore has a spectral distribution different to solar emissions. This work presents an instrumental system and procedure to obtain high spatial resolution LBIC maps in conditions approximating solar irradiation. The methodology developed consists of a trichromatic irradiation system based on three sources of laser excitation with emission in the red, green, and blue zones of the electromagnetic spectrum. The relative irradiation powers are determined by either solar spectrum distribution or Planck's emission formula which provides information approximate to the behavior of the system if it were under solar irradiation. In turn, an algorithm and a procedure have been developed to be able to form images based on the scans performed by the three lasers, providing information about the photoconverter efficiency of photovoltaic devices under the irradiation conditions used. This system has been checked with three photosensitive devices based on three different technologies: a commercial silicon photodiode, a commercial photoresistor, and a dye-sensitized solar cell. These devices make it possible to check how the superficial quantum efficiency has areas dependent upon the excitation wavelength while it has been possible to measure global incident photon-to-current efficiency values approximating those that would be obtained under irradiation conditions with sunlight.

  14. Spectroscopic data

    Melzer, J

    1976-01-01

    During the preparation of this compilation, many people contributed; the compilers wish to thank all of them. In particular they appreciate the efforts of V. Gilbertson, the manuscript typist, and those of K. C. Bregand, J. A. Kiley, and W. H. McPherson, who gave editorial assistance. They would like to thank Dr. J. R. Schwartz for his cooperation and encouragement. In addition, they extend their grati­ tude to Dr. L. Wilson of the Air Force Weapons Laboratory, who gave the initial impetus to this project. v Contents I. I ntroduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 . . . . . . . . . . . . . . . . 11. Organization ofthe Spectroscopic Table. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Methods of Production and Experimental Technique . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Band Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2...

  15. Spectroscopic enhancement in nanoparticles embedded glasses

    Sahar, M. R., E-mail: mrahim057@gmail.com; Ghoshal, S. K., E-mail: mrahim057@gmail.com [Advanced Optical Material Research Group, Department of Physics, Faculty of Science, Universiti Teknologi Malaysia, 81310, Skudai, Johor Bahru, Johor (Malaysia)

    2014-09-25

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  16. Characterisation of a smartphone image sensor response to direct solar 305nm irradiation at high air masses.

    Igoe, D P; Amar, A; Parisi, A V; Turner, J

    2017-06-01

    This research reports the first time the sensitivity, properties and response of a smartphone image sensor that has been used to characterise the photobiologically important direct UVB solar irradiances at 305nm in clear sky conditions at high air masses. Solar images taken from Autumn to Spring were analysed using a custom Python script, written to develop and apply an adaptive threshold to mitigate the effects of both noise and hot-pixel aberrations in the images. The images were taken in an unobstructed area, observing from a solar zenith angle as high as 84° (air mass=9.6) to local solar maximum (up to a solar zenith angle of 23°) to fully develop the calibration model in temperatures that varied from 2°C to 24°C. The mean ozone thickness throughout all observations was 281±18 DU (to 2 standard deviations). A Langley Plot was used to confirm that there were constant atmospheric conditions throughout the observations. The quadratic calibration model developed has a strong correlation between the red colour channel from the smartphone with the Microtops measurements of the direct sun 305nm UV, with a coefficient of determination of 0.998 and very low standard errors. Validation of the model verified the robustness of the method and the model, with an average discrepancy of only 5% between smartphone derived and Microtops observed direct solar irradiances at 305nm. The results demonstrate the effectiveness of using the smartphone image sensor as a means to measure photobiologically important solar UVB radiation. The use of ubiquitous portable technologies, such as smartphones and laptop computers to perform data collection and analysis of solar UVB observations is an example of how scientific investigations can be performed by citizen science based individuals and groups, communities and schools. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Solar Coronal Plumes

    Giannina Poletto

    2015-12-01

    Full Text Available Polar plumes are thin long ray-like structures that project beyond the limb of the Sun polar regions, maintaining their identity over distances of several solar radii. Plumes have been first observed in white-light (WL images of the Sun, but, with the advent of the space era, they have been identified also in X-ray and UV wavelengths (XUV and, possibly, even in in situ data. This review traces the history of plumes, from the time they have been first imaged, to the complex means by which nowadays we attempt to reconstruct their 3-D structure. Spectroscopic techniques allowed us also to infer the physical parameters of plumes and estimate their electron and kinetic temperatures and their densities. However, perhaps the most interesting problem we need to solve is the role they cover in the solar wind origin and acceleration: Does the solar wind emanate from plumes or from the ambient coronal hole wherein they are embedded? Do plumes have a role in solar wind acceleration and mass loading? Answers to these questions are still somewhat ambiguous and theoretical modeling does not provide definite answers either. Recent data, with an unprecedented high spatial and temporal resolution, provide new information on the fine structure of plumes, their temporal evolution and relationship with other transient phenomena that may shed further light on these elusive features.

  18. Solar monochromatic images in magneto-sensitive spectral lines and maps of vector magnetic fields

    Shihui, Y.; Jiehai, J.; Minhan, J.

    1985-01-01

    A new method which allows by use of the monochromatic images in some magneto-sensitive spectra line to derive both the magnetic field strength as well as the angle between magnetic field lines and line of sight for various places in solar active regions is described. In this way two dimensional maps of vector magnetic fields may be constructed. This method was applied to some observational material and reasonable results were obtained. In addition, a project for constructing the three dimensional maps of vector magnetic fields was worked out.

  19. High-resolution studies of the structure of the solar atmosphere using a new imaging algorithm

    Karovska, Margarita; Habbal, Shadia Rifai

    1991-01-01

    The results of the application of a new image restoration algorithm developed by Ayers and Dainty (1988) to the multiwavelength EUV/Skylab observations of the solar atmosphere are presented. The application of the algorithm makes it possible to reach a resolution better than 5 arcsec, and thus study the structure of the quiet sun on that spatial scale. The results show evidence for discrete looplike structures in the network boundary, 5-10 arcsec in size, at temperatures of 100,000 K.

  20. High-energy solar flare observations at the Y2K maximum

    Emslie, A. Gordon

    2000-04-01

    Solar flares afford an opportunity to observe processes associated with the acceleration and propagation of high-energy particles at a level of detail not accessible in any other astrophysical source. I will review some key results from previous high-energy solar flare observations, including those from the Compton Gamma-Ray Observatory, and the problems that they pose for our understanding of energy release and particle acceleration processes in the astrophysical environment. I will then discuss a program of high-energy observations to be carried out during the upcoming 2000-2001 solar maximum that is aimed at addressing and resolving these issues. A key element in this observational program is the High Energy Solar Spectroscopic Imager (HESSI) spacecraft, which will provide imaging spectroscopic observations with spatial, temporal, and energy resolutions commensurate with the physical processes believed to be operating, and will in addition provide the first true gamma-ray spectroscopy of an astrophysical source. .

  1. Cost-effective solar furnace system using fixed geometry Non-Imaging Focusing Heliostat and secondary parabolic concentrator

    Chong, K.K.; Lim, C.Y.; Hiew, C.W. [Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Off Jalan Genting Kelang, Setapak, Kuala Lumpur 53300 (Malaysia)

    2011-05-15

    A novel cost-effective solar furnace system is proposed to be consisted of a Non-Imaging Focusing Heliostat (NIFH) and a much smaller parabolic concentrator. In order to simplify the design and hence leading to the cost reduction, a fixed geometry of the NIFH heliostat is adopted in the novel solar furnace system by omitting the requirement of continuous astigmatic correction throughout the year with the use of local controllers. The performance of this novel solar furnace configuration can be optimized when the heliostat's spinning-axis is orientated in such a way that the annual variations of incident angle and therefore the annual variations of aberrant image size are the least. To verify the new configuration, a prototype solar furnace has been constructed at Universiti Tunku Abdul Rahman. (author)

  2. THE PLERIONIC SUPERNOVA REMNANT G21.5-0.9 POWERED BY PSR J1833-1034: NEW SPECTROSCOPIC AND IMAGING RESULTS REVEALED WITH THE CHANDRA X-RAY OBSERVATORY

    Matheson, Heather; Safi-Harb, Samar

    2010-01-01

    In 1999, the Chandra X-ray Observatory revealed a 150'' radius halo surrounding the 40'' radius pulsar wind nebula (PWN) G21.5-0.9. A 2005 imaging study of G21.5-0.9 showed that the halo is limb-brightened and suggested that this feature is a candidate for the long-sought supernova remnant (SNR) shell. We present a spectral analysis of SNR G21.5-0.9, using the longest effective observation to date (578.6 ks with the Advanced CCD Imaging Spectrometer (ACIS) and 278.4 ks with the High-Resolution Camera (HRC)) to study unresolved questions about the spectral nature of remnant features, such as the limb brightening of the X-ray halo and the bright knot in the northern part of the halo. The Chandra analysis favors the non-thermal interpretation of the limb. Its spectrum is fit well with a power-law model with a photon index Γ = 2.13 (1.94-2.33) and a luminosity of L x (0.5-8 keV) = (2.3 ± 0.6) x 10 33 erg s -1 (at an assumed distance of 5.0 kpc). An srcut model was also used to fit the spectrum between the radio and X-ray energies. While the absence of a shell in the radio still prohibits constraining the spectrum at radio wavelengths, we assume a range of spectral indices to infer the 1 GHz flux density and the rolloff frequency of the synchrotron spectrum in X-rays and find that the maximum energy to which electrons are accelerated at the shock ranges from ∼60 to 130 TeV (B/10 μG) -1/2 , where B is the magnetic field in units of μG. For the northern knot, we constrain previous models and find that a two-component power-law (or srcut) + pshock model provides an adequate fit, with the pshock model requiring a very low ionization timescale and solar abundances for Mg and Si. Our spectroscopic study of PSR J1833-1034, the highly energetic pulsar powering G21.5-0.9, shows that its spectrum is dominated by hard non-thermal X-ray emission with some evidence of a thermal component that represents ∼9% of the observed non-thermal emission and that suggests non

  3. Development of quality control and instrumentation performance metrics for diffuse optical spectroscopic imaging instruments in the multi-center clinical environment

    Keene, Samuel T.; Cerussi, Albert E.; Warren, Robert V.; Hill, Brian; Roblyer, Darren; Leproux, AnaÑ--s.; Durkin, Amanda F.; O'Sullivan, Thomas D.; Haghany, Hosain; Mantulin, William W.; Tromberg, Bruce J.

    2013-03-01

    Instrument equivalence and quality control are critical elements of multi-center clinical trials. We currently have five identical Diffuse Optical Spectroscopic Imaging (DOSI) instruments enrolled in the American College of Radiology Imaging Network (ACRIN, #6691) trial located at five academic clinical research sites in the US. The goal of the study is to predict the response of breast tumors to neoadjuvant chemotherapy in 60 patients. In order to reliably compare DOSI measurements across different instruments, operators and sites, we must be confident that the data quality is comparable. We require objective and reliable methods for identifying, correcting, and rejecting low quality data. To achieve this goal, we developed and tested an automated quality control algorithm that rejects data points below the instrument noise floor, improves tissue optical property recovery, and outputs a detailed data quality report. Using a new protocol for obtaining dark-noise data, we applied the algorithm to ACRIN patient data and successfully improved the quality of recovered physiological data in some cases.

  4. Comparison of structure and organization of cutaneous lipids in a reconstructed skin model and human skin: spectroscopic imaging and chromatographic profiling.

    Tfayli, Ali; Bonnier, Franck; Farhane, Zeineb; Libong, Danielle; Byrne, Hugh J; Baillet-Guffroy, Arlette

    2014-06-01

    The use of animals for scientific research is increasingly restricted by legislation, increasing the demand for human skin models. These constructs present comparable bulk lipid content to human skin. However, their permeability is significantly higher, limiting their applicability as models of barrier function, although the molecular origins of this reduced barrier function remain unclear. This study analyses the stratum corneum (SC) of one such commercially available reconstructed skin model (RSM) compared with human SC by spectroscopic imaging and chromatographic profiling. Total lipid composition was compared by chromatographic analysis (HPLC). Raman spectroscopy was used to evaluate the conformational order, lateral packing and distribution of lipids in the surface and skin/RSM sections. Although HPLC indicates that all SC lipid classes are present, significant differences are observed in ceramide profiles. Raman imaging demonstrated that the RSM lipids are distributed in a non-continuous matrix, providing a better understanding of the limited barrier function. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. A MULTISCALE APPROACH TO THE REPRESENTATION OF 3D IMAGES, WITH APPLICATION TO POLYMER SOLAR CELLS

    Ralf Thiedmann

    2011-03-01

    Full Text Available A multiscale approach to the description of geometrically complex 3D image data is proposed which distinguishes between morphological features on a ‘macro-scale’ and a ‘micro-scale’. Since our method is mainly tailored to nanostructures observed in composite materials consisting of two different phases, an appropriate binarization of grayscale images is required first. Then, a morphological smoothing is applied to extract the structural information from binarized image data on the ‘macro-scale’. A stochastic algorithm is developed for the morphologically smoothed images whose goal is to find a suitable representation of the macro-scale structure by unions of overlapping spheres. Such representations can be interpreted as marked point patterns. They lead to an enormous reduction of data and allow the application of well-known tools from point-process theory for their analysis and structural modeling. All those voxels which have been ‘misspecified’ by the morphological smoothing and subsequent representation by unions of overlapping spheres are interpreted as ‘micro-scale’ structure. The exemplary data sets considered in this paper are 3D grayscale images of photoactive layers in hybrid solar cells gained by electron tomography. These composite materials consist of two phases: a polymer phase and a zinc oxide phase. The macro-scale structure of the latter is represented by unions of overlapping spheres.

  6. First analysis of solar structures in 1.21 mm full-disc ALMA image of the Sun

    Brajša, R.; Sudar, D.; Benz, A. O.; Skokić, I.; Bárta, M.; Pontieu, B. De; Kim, S.; Kobelski, A.; Kuhar, M.; Shimojo, M.; Wedemeyer, S.; White, S.; Yagoubov, P.; Yan, Y.

    2018-05-01

    Context. Various solar features can be seen in emission or absorption on maps of the Sun in the millimetre and submillimetre wavelength range. The recently installed Atacama Large Millimetre/submillimetre Array (ALMA) is capable of observing the Sun in that wavelength range with an unprecedented spatial, temporal and spectral resolution. To interpret solar observations with ALMA, the first important step is to compare solar ALMA maps with simultaneous images of the Sun recorded in other spectral ranges. Aims: The first aim of the present work is to identify different structures in the solar atmosphere seen in the optical, infrared, and EUV parts of the spectrum (quiet Sun, active regions, prominences on the disc, magnetic inversion lines, coronal holes and coronal bright points) in a full-disc solar ALMA image. The second aim is to measure the intensities (brightness temperatures) of those structures and to compare them with the corresponding quiet Sun level. Methods: A full-disc solar image at 1.21 mm obtained on December 18, 2015, during a CSV-EOC campaign with ALMA is calibrated and compared with full-disc solar images from the same day in Hα line, in He I 1083 nm line core, and with various SDO images (AIA at 170 nm, 30.4 nm, 21.1 nm, 19.3 nm, and 17.1 nm and HMI magnetogram). The brightness temperatures of various structures are determined by averaging over corresponding regions of interest in the calibrated ALMA image. Results: Positions of the quiet Sun, active regions, prominences on the disc, magnetic inversion lines, coronal holes and coronal bright points are identified in the ALMA image. At the wavelength of 1.21 mm, active regions appear as bright areas (but sunspots are dark), while prominences on the disc and coronal holes are not discernible from the quiet Sun background, despite having slightly less intensity than surrounding quiet Sun regions. Magnetic inversion lines appear as large, elongated dark structures and coronal bright points correspond

  7. Spectroscopic study

    Flores, M.; Rodriguez, R.; Arroyo, R.

    1999-01-01

    This work is focused about the spectroscopic properties of a polymer material which consists of Polyacrylic acid (Paa) doped at different concentrations of Europium ions (Eu 3+ ). They show that to stay chemically joined with the polymer by a study of Nuclear Magnetic Resonance (NMR) of 1 H, 13 C and Fourier Transform Infrared Spectroscopy (Ft-IR) they present changes in the intensity of signals, just as too when this material is irradiated at λ = 394 nm. In according with the results obtained experimentally in this type of materials it can say that is possible to unify chemically the polymer with this type of cations, as well as, varying the concentration of them, since that these are distributed homogeneously inside the matrix maintaining its optical properties. These materials can be obtained more quickly and easy in solid or liquid phase and they have the best conditions for to make a quantitative analysis. (Author)

  8. Soft X-ray images of the solar corona using normal incidence optics

    Bruner, M. E.; Haisch, B. M.; Brown, W. A.; Acton, L. W.; Underwood, J. H.

    1988-01-01

    A solar coronal loop system has been photographed in soft X-rays using a normal incidence telescope based on multilayer mirror technology. The telescope consisted of a spherical objective mirror of 4 cm aperture and 1 m focal length, a film cassette, and a focal plane shutter. A metallized thin plastic film filter was used to exclude visible light. The objective mirror was covered with a multilayer coating consisting of alternating layers of tungsten and carbon whose combined thicknesses satisfied the Bragg diffraction condition for 44 A radiation. The image was recorded during a rocket flight on October 25, 1985 and was dominated by emission lines arising from the Si XII spectrum. The rocket also carried a high resolution soft X-ray spectrograph that confirmed the presence of Si XII line radiation in the source. This image represents the first successful use of multilayer technology for astrophysical observations.

  9. Short-circuit current density imaging of crystalline silicon solar cells via lock-in thermography: Robustness and simplifications

    Fertig, Fabian; Greulich, Johannes; Rein, Stefan

    2014-01-01

    Spatially resolved determination of solar cell parameters is beneficial for loss analysis and optimization of conversion efficiency. One key parameter that has been challenging to access by an imaging technique on solar cell level is short-circuit current density. This work discusses the robustness of a recently suggested approach to determine short-circuit current density spatially resolved based on a series of lock-in thermography images and options for a simplified image acquisition procedure. For an accurate result, one or two emissivity-corrected illuminated lock-in thermography images and one dark lock-in thermography image have to be recorded. The dark lock-in thermography image can be omitted if local shunts are negligible. Furthermore, it is shown that omitting the correction of lock-in thermography images for local emissivity variations only leads to minor distortions for standard silicon solar cells. Hence, adequate acquisition of one image only is sufficient to generate a meaningful map of short-circuit current density. Beyond that, this work illustrates the underlying physics of the recently proposed method and demonstrates its robustness concerning varying excitation conditions and locally increased series resistance. Experimentally gained short-circuit current density images are validated for monochromatic illumination in comparison to the reference method of light-beam induced current

  10. The Focusing Optics X-ray Solar Imager (FOXSI) SMEX Mission

    Christe, S.; Shih, A. Y.; Krucker, S.; Glesener, L.; Saint-Hilaire, P.; Caspi, A.; Allred, J. C.; Battaglia, M.; Chen, B.; Drake, J. F.; Gary, D. E.; Goetz, K.; Gburek, S.; Grefenstette, B.; Hannah, I. G.; Holman, G.; Hudson, H. S.; Inglis, A. R.; Ireland, J.; Ishikawa, S. N.; Klimchuk, J. A.; Kontar, E.; Kowalski, A. F.; Massone, A. M.; Piana, M.; Ramsey, B.; Schwartz, R.; Steslicki, M.; Turin, P.; Ryan, D.; Warmuth, A.; Veronig, A.; Vilmer, N.; White, S. M.; Woods, T. N.

    2017-12-01

    We present FOXSI (Focusing Optics X-ray Solar Imager), a Small Explorer (SMEX) Heliophysics mission that is currently undergoing a Phase A concept study. FOXSI will provide a revolutionary new perspective on energy release and particle acceleration on the Sun. FOXSI is a direct imaging X-ray spectrometer with higher dynamic range and better than 10x the sensitivity of previous instruments. Flown on a 3-axis-stabilized spacecraft in low-Earth orbit, FOXSI uses high-angular-resolution grazing-incidence focusing optics combined with state-of-the-art pixelated solid-state detectors to provide direct imaging of solar hard X-rays for the first time. FOXSI is composed of a pair of x-ray telescopes with a 14-meter focal length enabled by a deployable boom. Making use of a filter-wheel and high-rate-capable solid-state detectors, FOXSI will be able to observe the largest flares without saturation while still maintaining the sensitivity to detect x-ray emission from weak flares, escaping electrons, and hot active regions. This mission concept is made possible by past experience with similar instruments on two FOXSI sounding rocket flights, in 2012 and 2014, and on the HEROES balloon flight in 2013. FOXSI's hard X-ray imager has a field of view of 9 arcminutes and an angular resolution of better than 8 arcsec; it will cover the energy range from 3 up to 50-70 keV with a spectral resolution of better than 1 keV; and it will have sub-second temporal resolution.

  11. New techniques for the characterisation of dynamical phenomena in solar coronal images

    Robbrecht, E.

    2007-02-01

    During a total solar eclipse, a narrow strip of the Earth's surface is shielded completely by the Moon from the disk of the Sun. In this strip, the corona appears crown-like around the shade of the Moon. It was uncertain until the middle of the 20th century whether the corona was a solar phenomenon or if it was related to the Moon or whether it represented an artifact produced by the Earth's atmosphere. The answer to this question was provided by Grotrian (1939) and Edlèn (1942). Based on studies of iron emission lines, they suggested that the surface of the Sun is surrounded by a hot tenuous gas having a temperature of million degrees Kelvin and thus in a state of high ionization. This discovery was a result from spectroscopy, a field of research which started in 1666 with Sir Isaac Newton's observations of sunlight, dispersed by a prism. It is now clear that the hot solar corona is made of a low density plasma, highly structured by the magnetic field on length scales ranging from the Sun's diameter to the limit of angular resolution (e.g. Démoulin and Klein 2000). The need to resolve and study the corona down to such scales has determined a vigorous scientific and technological impulse toward the development of solar Ultraviolet (UV) and X-ray telescopes with high spatial and temporal resolution. With the advent of the satellite SOHO (Solar and Heliospheric Observatory, see chapter 1), the picture of a quiet corona was definitely sent to the past. EUV (Extreme UV) image sequences of the lower solar corona revealed a finely structured medium constantly agitated by a wide variety of transients (e.g. Harrison 1998). Active regions consisting of large magnetic loops with enhanced temperature and density are observed, as well as "quiet" areas, coronal holes and numerous structures of different scales such as plumes, jets, spicules, X-ray bright points, blinkers, all structured by magnetic fields. Launched in 1998, the Transition Region And Coronal Explorer (TRACE

  12. Satellite image analysis and a hybrid ESSS/ANN model to forecast solar irradiance in the tropics

    Dong, Zibo; Yang, Dazhi; Reindl, Thomas; Walsh, Wilfred M.

    2014-01-01

    Highlights: • Satellite image analysis is performed and cloud cover index is classified using self-organizing maps (SOM). • The ESSS model is used to forecast cloud cover index. • Solar irradiance is estimated using multi-layer perceptron (MLP). • The proposed model shows better accuracy than other investigated models. - Abstract: We forecast hourly solar irradiance time series using satellite image analysis and a hybrid exponential smoothing state space (ESSS) model together with artificial neural networks (ANN). Since cloud cover is the major factor affecting solar irradiance, cloud detection and classification are crucial to forecast solar irradiance. Geostationary satellite images provide cloud information, allowing a cloud cover index to be derived and analysed using self-organizing maps (SOM). Owing to the stochastic nature of cloud generation in tropical regions, the ESSS model is used to forecast cloud cover index. Among different models applied in ANN, we favour the multi-layer perceptron (MLP) to derive solar irradiance based on the cloud cover index. This hybrid model has been used to forecast hourly solar irradiance in Singapore and the technique is found to outperform traditional forecasting models

  13. Image-based reconstruction of the Newtonian dynamics of solar coronal ejecta

    Uritsky, Vadim M.; Thompson, Barbara J.

    2016-10-01

    We present a new methodology for analyzing rising and falling dynamics of unstable coronal material as represented by high-cadence SDO AIA images. The technique involves an adaptive spatiotemporal tracking of propagating intensity gradients and their characterization in terms of time-evolving areas swept out by the position vector originated from the Sun disk center. The measured values of the areal velocity and acceleration are used to obtain quantitative information on the angular momentum and acceleration along the paths of the rising and falling coronal plasma. In the absence of other forces, solar gravitation results in purely ballistic motions consistent with the Kepler's second law; non-central forces such as the Lorentz force introduce non-zero torques resulting in more complex motions. The developed algorithms enable direct evaluation of the line-of-sight component of the net torque applied to a unit mass of the ejected coronal material which is proportional to the image-plane projection of the observed areal acceleration. The current implementation of the method cannot reliably distinguish torque modulations caused by the coronal force field from those imposed by abrupt changes of plasma mass density and nontrivial projection effects. However, it can provide valid observational constraints on the evolution of large-scale unstable magnetic topologies driving major solar-coronal eruptions as demonstrated in the related talk by B. Thompson et al.

  14. Spectroscopic study on the doping of polycrystalline CdTe layers for solar cells; Spektroskopische Untersuchungen zur Dotierung von polykristallinen CdTe-Schichten fuer Solarzellen

    Kraft, Christian

    2011-11-29

    First in the present thesis the fundamental properties of CdTe are described. In the following it is discussed, how a CdTe solar cell is generally constructed, which specialities are to be regarded, and how an improvement of the actually reachable data of such a solar cell in view of the efficiency can be reached fundamentally and in then practical realization. In the third chapter the physical foundations of the most important methods are discussed, which are applied in the framework of this thesis for the analysis of the CdTe layers. The fourth chapter describes the details of the experiments of this thesis. The fifth chapter deals with the analysis of the photoluminescence of CdTe layers. Special attention is put on the analysis of the excitonic luminescence. The sixth chapter treats the implantation of CdTe layers with phosphor. The influence of phosphorus as dopant on the PL spectra of CdTe and the correponding characteristics of implanted solar cells are presented. Also the influence of radiation damages as consequence of the ion implantation is studied in this chapter by means of the analysis of differently thick absorber layers. In the seventh chapter finally a new procedure for the fabrication of solar cells on the base of CdTe as absorber material is introduced, which shall make possible to change the stoichiometry of cadmium mand tellurium specifically and to present additionally a suited material, in order to form the doping of CdTE a solar-cell material variably. The fundamental properties of the new facility are experimentally determined, and first solar cells are fabricated with this facility and analyzed. Also an in-situ doping with phosphorus is thereby performed and the result studied.

  15. {sup 1}H-MR-spectroscopic imaging in patients with Alzheimer`s disease; {sup 1}H-MR-spektroskopische Bildgebung bei Patienten mit klinisch gesichertem Morbus Alzheimer

    Block, W [Radiogische Klinik der Univ. Bonn (Germany); Traeber, F [Radiogische Klinik der Univ. Bonn (Germany); Kuhl, C K [Radiogische Klinik der Univ. Bonn (Germany); Fric, M [Psychiatrische Universitaetsklinik, Bonn (Germany); Keller, E [Radiogische Klinik der Univ. Bonn (Germany); Lamerichs, R [Philips Medical Systems, Best (Netherlands); Rink, H [Radiogische Klinik der Univ. Bonn (Germany); Moeller, H J [Psychiatrische Universitaetsklinik, Bonn (Germany); Schild, H H [Radiogische Klinik der Univ. Bonn (Germany)

    1995-09-01

    To detect regional differences in accompanying metabolic changes, {sup 1}H-Magnetic Resonance Spectroscopic Imaging was performed in 16 patients with Alzheimer`s disease (AD); the clinical diagnosis was based upon DSM-III-R and NINCDS-ADRDA guidelines. In the hippocampal region metabolic maps of the local distribution of N-acetylaspartate (NAA), choline (Cho), creatine compounds (P(Cr)) and lactate were determined. Ratios of Cho/NAA, (P)Cr/NAA and Cho/(P)Cr calculated from selected hippocampal spectra were compared to those from healthy volunteers (n=17). AD patients demonstrated an increase of Cho/NAA and (P)Cr/NAA ratios caused by increased choline compounds and decreased NAA. These alterations were observed in 11/12 cases in the hippocampal and in 7/12 in the temporo-occipital region. Hippocampal Cho/NAA ratios (0.56{+-}0.19) were significantly elevated compared with controls. The observed elevation of choline compounds in the hippocampus supports the hypothesis that alterations in the cholinergic system play an important role in Alzheimer`s disease. The observed reduction of NAA is due to neuronal degeneration. (orig./MG) [Deutsch] Zur Darstellung von regionalen metabolischen Veraenderungen bei Morbus Alzheimer wurden mit dem Verfahren des {sup 1}H-Magnetic-Resonance-Spectroscopic-Imaging 16 Patienten untersucht, deren Diagnose klinisch entsprechend DSM-III-R- und NINCDS-ADRDA-Kriterien gestellt wurde. In Hoehe des Hippocampus wurden transaxiale ``Metabolitenkarten`` der regionalen Verteilung von N-Acetyl-Aspartat (NAA), cholinhaltiger Verbindungen (Cho), Gesamtkreatin (P(Cr)) und Laktat erstellt. Zur Quantifizierung der Unterschiede zum Normalkollektiv (n=17) wurden die Metabolitenquotienten Cho/NAA, (P)Cr/NAA und Cho/(P)Cr, insbesondere aus der Hippocampusregion, ermittelt. Das Krankheitsbild des M. Alzheimer stellte sich durch eine Erhoehung der Quotienten Cho/NAA und Cho/(P)Cr dar, wobei neben einer Cholinerhoehung die Reduktion des Neurotransmitters NAA

  16. Built-in hyperspectral camera for smartphone in visible, near-infrared and middle-infrared lights region (second report): sensitivity improvement of Fourier-spectroscopic imaging to detect diffuse reflection lights from internal human tissues for healthcare sensors

    Kawashima, Natsumi; Hosono, Satsuki; Ishimaru, Ichiro

    2016-05-01

    We proposed the snapshot-type Fourier spectroscopic imaging for smartphone that was mentioned in 1st. report in this conference. For spectroscopic components analysis, such as non-invasive blood glucose sensors, the diffuse reflection lights from internal human skins are very weak for conventional hyperspectral cameras, such as AOTF (Acousto-Optic Tunable Filter) type. Furthermore, it is well known that the spectral absorption of mid-infrared lights or Raman spectroscopy especially in long wavelength region is effective to distinguish specific biomedical components quantitatively, such as glucose concentration. But the main issue was that photon energies of middle infrared lights and light intensities of Raman scattering are extremely weak. For improving sensitivity of our spectroscopic imager, the wide-field-stop & beam-expansion method was proposed. Our line spectroscopic imager introduced a single slit for field stop on the conjugate objective plane. Obviously to increase detected light intensities, the wider slit width of the field stop makes light intensities higher, regardless of deterioration of spatial resolutions. Because our method is based on wavefront-division interferometry, it becomes problems that the wider width of single slit makes the diffraction angle narrower. This means that the narrower diameter of collimated objective beams deteriorates visibilities of interferograms. By installing the relative inclined phaseshifter onto optical Fourier transform plane of infinity corrected optical systems, the collimated half flux of objective beams derived from single-bright points on objective surface penetrate through the wedge prism and the cuboid glass respectively. These two beams interfere each other and form the infererogram as spatial fringe patterns. Thus, we installed concave-cylindrical lens between the wider slit and objective lens as a beam expander. We successfully obtained the spectroscopic characters of hemoglobin from reflected lights from

  17. Direct imaging of extra-solar planetary systems with the Circumstellar Imaging Telescope (CIT)

    Terrile, R.J.

    1988-01-01

    In a joint study conducted by the Jet Propulsion Laboratory and the Perkin-Elmer Corporation it was found that an earth orbital, 1.5 meter diameter low scattered light coronagraphic telescope can achieve a broad range of scientific objectives including the direct detection of Jupiter-sized planets around the nearby stars. Recent major advances in the understanding of coronagraphic performance and in the field of super smooth mirror fabrication allow such an instrument to be designed and built within current technology. Such a project, called the Circumstellar Imaging Telescope (CIT), is currently being proposed. 10 references

  18. Eclipse Megamovie: Solar Discoveries, Education, and Outreach through Crowdsourcing 2017 Eclipse Images

    Peticolas, L. M.; Hudson, H. S.; Martinez Oliveros, J. C.; Johnson, C.; Zevin, D.; Krista, L. D.; Bender, M.; Mcintosh, S. W.; Konerding, D.; Koh, J.; Pasachoff, J.; Lorimore, B.; Jiang, G.; Storksdieck, M.; Yan, D.; Shore, L.; Fraknoi, A.; Filippenko, A.

    2016-12-01

    Since 2011, a team of solar scientists, eclipse chasers, education and outreach professionals, and film makers have been working to explore the possibility of gathering images from the public during the 2017 eclipse across the United States, to be used for scientific research, education, and enhancing the public's experience of the eclipse. After years of testing the initial ideas, engaging new organizations, and exploring new technologies, our team has developed a blueprint for this project. There are three main goals for this effort: 1. to learn more about the dynamic non-equilibrium processes in the corona and lower atmosphere of the Sun, 2. to educate the public about space physics, 3. provide different levels of engagement opportunities for an interested public, and 4. to understand how these various levels of engagement with a major scientific phenomena allow people to develop deeper personal connections to Science, Technology, Engineering, and Mathematics (STEM). We will meet these goals by training 1000 volunteers to take scientifically valid images and donate the images to this project, while also allowing the general public to share their images as well. During the Aug 21, 2017 eclipse, we will analyze these images in real-time to produce public-generated movies showing the corona of the Sun during totality from thousands of people. These movies will be disseminated in near real-time (on the order of 10s of minutes) to other eclipse programs, news organizations, and to the general public. Meanwhile, images collected during and after the eclipse will be available to scientists and the public for research purposes. To further engage the public, video clips, film, and a documentary will be produced prior and after the event. A science education research team will work alongside the team to understand how the project supports deeper connections to the eclipse experience.

  19. UNDERCOVER EUV SOLAR JETS OBSERVED BY THE INTERFACE REGION IMAGING SPECTROGRAPH

    Chen, N.-H. [Korea Astronomy and Space Science Institute, Daejeon (Korea, Republic of); Innes, D. E. [Max-Planck-Institut für Sonnensystemforschung, D-37077 Göttingen (Germany)

    2016-12-10

    It is well-known that extreme ultraviolet (EUV) emission emitted at the solar surface is absorbed by overlying cool plasma. Especially in active regions, dark lanes in EUV images suggest that much of the surface activity is obscured. Simultaneous observations from the Interface Region Imaging Spectrograph, consisting of UV spectra and slit-jaw images (SJI), give vital information with sub-arcsecond spatial resolution on the dynamics of jets not seen in EUV images. We studied a series of small jets from recently formed bipole pairs beside the trailing spot of active region 11991, which occurred on 2014 March 5 from 15:02:21 UT to 17:04:07 UT. Collimated outflows with bright roots were present in SJI 1400 Å (transition region) and 2796 Å (upper chromosphere) that were mostly not seen in Atmospheric Imaging Assembly (AIA) 304 Å (transition region) and AIA 171 Å (lower corona) images. The Si iv spectra show a strong blue wing enhancement, but no red wing, in the line profiles of the ejecta for all recurrent jets, indicating outward flows without twists. We see two types of Mg ii line profiles produced by the jets spires: reversed and non-reversed. Mg ii lines remain optically thick, but turn optically thin in the highly Doppler shifted wings. The energy flux contained in each recurrent jet is estimated using a velocity differential emission measure technique that measures the emitting power of the plasma as a function of the line-of-sight velocity. We found that all the recurrent jets release similar energy (10{sup 8} erg cm{sup −2} s{sup −1}) toward the corona and the downward component is less than 3%.

  20. DYNAMICS IN SUNSPOT UMBRA AS SEEN IN NEW SOLAR TELESCOPE AND INTERFACE REGION IMAGING SPECTROGRAPH DATA

    Yurchyshyn, V.; Abramenko, V. [Big Bear Solar Observatory, New Jersey Institute of Technology, Big Bear City, CA 92314 (United States); Kilcik, A. [Department of Space Science and Technologies, Akdeniz University, 07058 Antalya (Turkey)

    2015-01-10

    We analyze sunspot oscillations using Interface Region Imaging Spectrograph (IRIS) slit-jaw and spectral data and narrow-band chromospheric images from the New Solar Telescope (NST) for the main sunspot in NOAA AR 11836. We report that the difference between the shock arrival times as measured by the Mg II k 2796.35 Å and Si IV 1393.76 Å line formation levels changes during the observed period, and peak-to-peak delays may range from 40 s to zero. The intensity of chromospheric shocks also displays long-term (about 20 min) variations. NST's high spatial resolution Hα data allowed us to conclude that, in this sunspot, umbral flashes (UFs) appeared in the form of narrow bright lanes stretched along the light bridges and around clusters of umbral bright points. The time series also suggested that UFs preferred to appear on the sunspot-center side of light bridges, which may indicate the existence of a compact sub-photospheric driver of sunspot oscillations. The sunspot's umbra as seen in the IRIS chromospheric and transition region data appears bright above the locations of light bridges and the areas where the dark umbra is dotted with clusters of umbral dots. Co-spatial and co-temporal data from the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory showed that the same locations were associated with bright footpoints of coronal loops suggesting that the light bridges may play an important role in heating the coronal sunspot loops. Finally, the power spectra analysis showed that the intensity of chromospheric and transition region oscillations significantly vary across the umbra and with height, suggesting that umbral non-uniformities and the structure of sunspot magnetic fields may play a role in wave propagation and heating of umbral loops.

  1. Solar irradiance assessment in insular areas using Himawari-8 satellite images

    Liandrat, O.; Cros, S.; Turpin, M.; Pineau, J. F.

    2016-12-01

    The high amount of surface solar irradiance (SSI) in the tropics is an advantage for a profitable PV production. It will allow many tropical islands to pursue their economic growth with a clean, affordable and locally produced energy. However, the local meteorological conditions induce a very high variability which is problematic for a safe and gainful injection into the power grid. This issue is even more critical in non-interconnected territories where network stability is an absolute necessity. Therefore, the injection of PV power is legally limited in some European oversea territories. In this context, intraday irradiance forecasting (several hours ahead) is particularly useful to mitigate the production variability by reducing the cost of power storage management. At this time scale, cloud cover evolves with a stochastic behaviour not properly represented in numerical weather prediction (NWP) models. Analysing cloud motion using images from geostationary meteorological satellites is a well-known alternative to forecasting SSI up to 6 hours ahead with a better accuracy than NWP models. In this study, we present and apply our satellite-based solar irradiance forecasting methods over two measurement sites located in the field of view of the satellite Himawari-8: Cocos (Keeling) Islands (Australia) and New Caledonia (France). In particular, we converted 4 months of images from Himawari-8 visible channel into cloud index maps. Then, we applied an algorithm computing a cloud motion vector field from a short sequence of consecutive images. Comparisons between forecasted SSI at 1 hour of time horizon and collocated pyranometric measurements show a relative RMSE between 20 and 27%. Error sources related to the tropic insular context (coastal area heterogeneity, sub-pixel scale orographic cloud appearance, convective situation…) are discussed at every implementation step for the different methods.

  2. Translational Approaches for Studying Neurodevelopmental Disorders Utilizing in Vivo Proton (+H) Magnetic Resonance Spectroscopic Imaging in Rats

    Ronca, April E.

    2014-01-01

    Intrauterine complications have been implicated in the etiology of neuripsychiatric disorders including schizophrenia, autism and ADHD. This presentation will describe new translational studies derived from in vivo magnetic resonance imaging of developing and adult brain following perinatal asphyxia (PA). Our findings reveal significant effects of PA on neurometabolic profiles at one week of age, and significant relationships between early metabolites and later life phenotypes including behavior and brain morphometry

  3. Assessment of optical performance of three non-tracking, non-imaging, external compound parabolic concentrators designed for high temperature solar thermal collector units

    Cisneros, Jesus

    2010-01-01

    The objective of this thesis is to perform a preliminary optical assessment of the external compound parabolic concentrator (XCPC) component in three concentrating solar thermal units. Each solar thermal unit consists an optical element (the non-imaging concentrating reflector) and a thermal element (the evacuated glass tube solar absorber). The three concentrating solar thermal units discussed in this work are DEWAR 58, a direct flow all-glass dewar, DEWAR 47 an indirect flow ...

  4. Single nanoparticle tracking spectroscopic microscope

    Yang, Haw [Moraga, CA; Cang, Hu [Berkeley, CA; Xu, Cangshan [Berkeley, CA; Wong, Chung M [San Gabriel, CA

    2011-07-19

    A system that can maintain and track the position of a single nanoparticle in three dimensions for a prolonged period has been disclosed. The system allows for continuously imaging the particle to observe any interactions it may have. The system also enables the acquisition of real-time sequential spectroscopic information from the particle. The apparatus holds great promise in performing single molecule spectroscopy and imaging on a non-stationary target.

  5. Acute Solar Retinopathy Imaged With Adaptive Optics, Optical Coherence Tomography Angiography, and En Face Optical Coherence Tomography.

    Wu, Chris Y; Jansen, Michael E; Andrade, Jorge; Chui, Toco Y P; Do, Anna T; Rosen, Richard B; Deobhakta, Avnish

    2018-01-01

    Solar retinopathy is a rare form of retinal injury that occurs after direct sungazing. To enhance understanding of the structural changes that occur in solar retinopathy by obtaining high-resolution in vivo en face images. Case report of a young adult woman who presented to the New York Eye and Ear Infirmary with symptoms of acute solar retinopathy after viewing the solar eclipse on August 21, 2017. Results of comprehensive ophthalmic examination and images obtained by fundus photography, microperimetry, spectral-domain optical coherence tomography (OCT), adaptive optics scanning light ophthalmoscopy, OCT angiography, and en face OCT. The patient was examined after viewing the solar eclipse. Visual acuity was 20/20 OD and 20/25 OS. The patient was left-eye dominant. Spectral-domain OCT images were consistent with mild and severe acute solar retinopathy in the right and left eye, respectively. Microperimetry was normal in the right eye but showed paracentral decreased retinal sensitivity in the left eye with a central absolute scotoma. Adaptive optics images of the right eye showed a small region of nonwaveguiding photoreceptors, while images of the left eye showed a large area of abnormal and nonwaveguiding photoreceptors. Optical coherence tomography angiography images were normal in both eyes. En face OCT images of the right eye showed a small circular hyperreflective area, with central hyporeflectivity in the outer retina of the right eye. The left eye showed a hyperreflective lesion that intensified in area from inner to middle retina and became mostly hyporeflective in the outer retina. The shape of the lesion on adaptive optics and en face OCT images of the left eye corresponded to the shape of the scotoma drawn by the patient on Amsler grid. Acute solar retinopathy can present with foveal cone photoreceptor mosaic disturbances on adaptive optics scanning light ophthalmoscopy imaging. Corresponding reflectivity changes can be seen on en face OCT, especially

  6. Reproducibility of proton MR spectroscopic imaging (PEPSI): comparison of dyslexic and normal-reading children and effects of treatment on brain lactate levels during language tasks.

    Richards, Todd L; Berninger, Virginia W; Aylward, Elizabeth H; Richards, Anne L; Thomson, Jennifer B; Nagy, William E; Carlisle, Joanne F; Dager, Stephen R; Abbott, Robert D

    2002-01-01

    We repeated a proton echo-planar spectroscopic imaging (PEPSI) study to test the hypothesis that children with dyslexia and good readers differ in brain lactate activation during a phonologic judgment task before but not after instructional treatment. We measured PEPSI brain lactate activation (TR/TE, 4000/144; 1.5 T) at two points 1-2 months apart during two language tasks (phonologic and lexical) and a control task (passive listening). Dyslexic participants (n = 10) and control participants (n = 8) (boys and girls aged 9-12 years) were matched in age, verbal intelligence quotients, and valid PEPSI voxels. In contrast to patients in past studies who received combined treatment, our patients were randomly assigned to either phonologic or morphologic (meaning-based) intervention between the scanning sessions. Before treatment, the patients showed significantly greater lactate elevation in the left frontal regions (including the inferior frontal gyrus) during the phonologic task. Both patients and control subjects differed significantly in the right parietal and occipital regions during both tasks. After treatment, the two groups did not significantly differ in any brain region during either task, but individuals given morphologic treatment were significantly more likely to have reduced left frontal lactate activation during the phonologic task. The previous finding of greater left frontal lactate elevation in children with dyslexia during a phonologic judgment task was replicated, and brain activation changed as a result of treatment. However, the treatment effect was due to the morphologic component rather than the phonologic component.

  7. Reproducibility over a 1-month period of 1H-MR spectroscopic imaging NAA/Cr ratios in clinically stable multiple sclerosis patients.

    Mostert, J P; Blaauw, Y; Koch, M W; Kuiper, A J; Hoogduin, J M; De Keyser, J

    2008-08-01

    N-acetylaspartate/creatine (NAA/Cr) ratios, assessed with proton magnetic resonance spectroscopy, are increasingly used as a surrogate marker for axonal dysfunction and degeneration in multiple sclerosis (MS). The purpose of this study was to test short-time reproducibility of NAA/Cr ratios in patients with clinically stable MS. In 35 MS patients we analysed NAA/Cr ratios obtained with (1)H-MR spectroscopic imaging at the centrum semiovale either with lateral ventricles partially included (group 1; n=15) or more cranially with no ventricles included (group 2; n=20). To test short-term reproducibility of the NAA/Cr measurements, patients were scanned twice 4 weeks apart. We determined mean NAA/Cr and Cho/Cr ratios of 12 grey matter and 24 white matter voxels. Mean NAA/Cr ratios of both the white and grey matter did not change after 4 weeks. Overall 4-week reproducibility of the NAA/Cr ratio, expressed as coefficient of variation, was 4.8% for grey matter and 3.5% for white matter. Reproducibility of cranial scanning of the ventricles was slightly better than with cerebrospinal fluid included. Our study shows good short-term reproducibility of NAA/Cr ratio measurements in the centrum semiovale, which supports the reliability of this technique for longitudinal studies.

  8. Use of spectroscopic and imaging techniques to evaluate pretreated sugarcane bagasse as a substrate for cellulase production under solid-state fermentation.

    Rodríguez-Zúñiga, Ursula Fabiola; Bertucci Neto, Victor; Couri, Sonia; Crestana, Silvio; Farinas, Cristiane Sanchez

    2014-03-01

    The enzymatic cocktail of cellulases is one of the most costly inputs affecting the economic viability of the biochemical route for biomass conversion into biofuels and other chemicals. Here, the influence of liquid hot water, dilute acid, alkali, and combined acid/alkali pretreatments on sugarcane bagasse (SCB) used for cellulase production was investigated by means of spectroscopic and imaging techniques. Chemical composition and structural characteristics, such as crystallinity (determined by X-ray diffraction), functional groups (Fourier transform infrared spectroscopy), and microstructure (scanning electron microscopy), were used to correlate SCB pretreatments with enzymatic biosynthesis by a strain of the filamentous fungus Aspergillus niger under solid-state fermentation. The combined acid/alkali pretreatment resulted in a SCB with higher cellulose content (86.7%). However, the high crystallinity (74%) of the resulting biomass was detrimental to microbial uptake and enzyme production. SCB pretreated with liquid hot water yielded the highest filter paper cellulase (FPase), carboxymethyl cellulase (CMCase), and xylanase activities (0.4, 14.9, and 26.1 U g(-1), respectively). The results showed that a suitable pretreatment for SCB to be used as a substrate for cellulase production should avoid severe conditions in order to preserve amorphous cellulose and to enhance the physical properties that assist microbial access.

  9. Localization of calcium in the cyanobiont and gonidial zone of Cycas revoluta Thunb. by microelectrodes, chlorotetracycline, electron spectroscopic imaging and electron energy loss spectroscopy

    Caiola, M.G.; Canini, A.; Brandizzi, F.

    1994-01-01

    Ionic calcium concentration was measured in the gonidial zone of fresh coralloid roots by means of calcium microelectrodes. It was 10 -6 M in the apical segments of coralloid roots and increased to 10 -5 M in the gonidial zones of median and basal segments. Loosely membrane-bound calcium was evidenced by using chloro-tetracycline (CTC) or ethylene glycol-bis-(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) and CTC, in cell walls of columnar cells of Cycas and in the cytoplasm of cyanobiont. Sub-cellular localization of calcium was obtained by electron spectroscopic imaging (ESI) and electron energy loss spectroscopy (EELS) analyses applied at transmission electron microscopy on thin, unstained sections of gonidial zone of coralloid roots. By means of these techniques, bound-calcium was detected inside the mucilage of apical and median segments whereas, in the basal segments, it was completely absent. In the heterocysts of apical segments of coralloid, calcium was localized on the envelope, cell walls, thylakoids and cyanophycin granules. In the gonidial zone of the basal segments, dead or degenerating heterocysts completely lacked calcium. Therefore, the high ionic calcium amounts detected in the gonidial zone of median and basal segments could represent a minor calcium uptake by the cells or release by lysed ones. The decreases in nitrogenase activity recorded in the median and basal segments of the coralloid roots paralleled the decrease in calcium amount in heterocyst envelope. (authors)

  10. Imaging and spectroscopic observations of a strange elliptical bubble in the northern arm of the spiral galaxy NGC 6946

    Efremov, Yuri N.; Moiseev, Alexei V.

    2016-01-01

    NGC 6946, known as the Fireworks galaxy because of its high supernova rate and high star formation, is embedded in a very extended HI halo. Its northern spiral arm is well detached from the galactic main body. We found that this arm contains a large (~300 pc in size) Red Ellipse, named according to a strong contamination of the H-alpha emission line on its optical images. The ellipse is accompanied by a short parallel arc and a few others still smaller and less regular; a bright star cluster ...

  11. Numerical and experimental analysis of a point focus solar collector using high concentration imaging PMMA Fresnel lens

    Xie, W.T.; Dai, Y.J.; Wang, R.Z.

    2011-01-01

    Research highlights: → We studied a point focus Fresnel solar collector using different cavity receivers. → The collector heat removal factors are derived to find the optimal cavity shape. → Numerical and experimental analysis shows that the conical cavity is optimum. -- Abstract: A high concentration imaging Fresnel solar collector provided with different cavity receivers was developed and its behavior was investigated. Round copper pipes winded into different spring shapes were used as receiver by placing in the cylindrical cavity to absorb concentrated solar energy and transfer it to a heat transfer fluid (HTF). The collector efficiency factor and collector heat removal factor were derived for the cavity receivers to find out heat transfer mechanism and to propose an effective way for evaluating the performance of Fresnel solar collector and determining the optimal cavity structure. The problem of Fresnel solar collector with synthetic heat transfer oil flow was simulated and analyzed to investigate heat loss from different cavity receivers. Solar irradiation as well as convection and heat transfer in the circulating fluid and between the internal surfaces of the cavity and the environment are considered in the model. The temperature distribution over its area as well as the collector thermal efficiency at nominal flow rate was used in order to validate the simulation results. It was found that the simulated temperature distribution during operation and the average collector efficiency are in good agreement with the experimental data. Finally, the optimal shape of solar cavity receiver, as well as its thermal performance, are deeply analyzed and discussed.

  12. A Raman scattering and FT-IR spectroscopic study on the effect of the solar radiation in Antarctica on bovine cornea

    Yamamoto, Tatsuyuki; Murakami, Naoki; Yoshikiyo, Keisuke; Takahashi, Tetsuya; Yamamoto, Naoyuki

    2010-01-01

    The Raman scattering and FT-IR spectra of the corneas, transported to the Syowa station in Antarctica and exposed to the solar radiation of the mid-summer for four weeks, were studied to reveal that type IV collagen involved in corneas were fragmented. The amide I and III Raman bands were observed at 1660 and 1245 cm -1, respectively, and the amide I and II infrared bands were observed at 1655 and 1545 cm -1, respectively, for original corneas before exposure. The background of Raman signals prominently increased and the ratio of amide II infrared band versus amide I decreased by the solar radiation in Antarctica. The control experiment using an artificial UV lamp was also performed in laboratory. The decline rate of the amide II/amide I was utilized for estimating the degree of fragmentation of collagen, to reveal that the addition of vitamin C suppressed the reaction while the addition of sugars promoted it. The effect of the solar radiation in Antarctica on the corneas was estimated as the same as the artificial UV lamp of four weeks (Raman) or one week (FT-IR) exposure.

  13. 1H Spectroscopic Imaging of Human Brain at 3T: Comparison of Fast 3D-MRSI Techniques

    Zierhut, Matthew L.; Ozturk-Isik, Esin; Chen, Albert P.; Park, Ilwoo; Vigneron, Daniel B.; Nelson, Sarah J.

    2011-01-01

    Purpose To investigate the signal-to-noise-ratio (SNR) and data quality of time-reduced 1H 3D-MRSI techniques in the human brain at 3T. Materials and Methods Techniques that were investigated included ellipsoidal k-space sampling, parallel imaging, and EPSI. The SNR values for NAA, Cho, Cre, and lactate or lipid peaks were compared after correcting for effective spatial resolution and acquisition time in a phantom and in the brains of human volunteers. Other factors considered were linewidths, metabolite ratios, partial volume effects, and subcutaneous lipid contamination. Results In volunteers, the median normalized SNR for parallel imaging data decreased by 34–42%, but could be significantly improved using regularization. The normalized signal to noise loss in flyback EPSI data was 11–18%. The effective spatial resolutions of the traditional, ellipsoidal, SENSE, and EPSI data were 1.02, 2.43, 1.03, and 1.01cm3, respectively. As expected, lipid contamination was variable between subjects but was highest for the SENSE data. Patient data obtained using the flyback EPSI method were of excellent quality. Conclusions Data from all 1H 3D-MRSI techniques were qualitatively acceptable, based upon SNR, linewidths, and metabolite ratios. The larger FOV obtained with the EPSI methods showed negligible lipid aliasing with acceptable SNR values in less than 9.5 minutes without compromising the PSF. PMID:19711396

  14. Regarding the Focal Treatment of Prostate Cancer: Inference of the Gleason Grade From Magnetic Resonance Spectroscopic Imaging

    Brame, Ryan S.; Zaider, Marco; Zakian, Kristen L.; Koutcher, Jason A.; Shukla-Dave, Amita; Reuter, Victor E.; Zelefsky, Michael J.; Scardino, Peter T.; Hricak, Hedvig

    2009-01-01

    Purpose: To quantify, as a function of average magnetic resonance spectroscopy (MRS) score and tumor volume, the probability that a cancer-suspected lesion has an elevated Gleason grade. Methods and Materials: The data consist of MRS imaging ratios R stratified by patient, lesion (contiguous abnormal voxels), voxels, biopsy and pathologic Gleason grade, and lesion volume. The data were analyzed using a logistic model. Results: For both low and high Gleason score biopsy lesions, the probability of pathologic Gleason score ≥4+3 increases with lesion volume. At low values of R a lesion volume of at least 15-20 voxels is needed to reach a probability of success of 80%; the biopsy result helps reduce the prediction uncertainty. At larger MRS ratios (R > 6) the biopsy result becomes essentially uninformative once the lesion volume is >12 voxels. With the exception of low values of R, for lesions with low Gleason score at biopsy, the MRS ratios serve primarily as a selection tool for assessing lesion volumes. Conclusions: In patients with biopsy Gleason score ≥4+3, high MRS imaging tumor volume and (creatine + choline)/citrate ratio may justify the initiation of voxel-specific dose escalation. This is an example of biologically motivated focal treatment for which intensity-modulated radiotherapy and especially brachytherapy are ideally suited.

  15. Development of a muon radiographic imaging electronic board system for a stable solar power operation

    Uchida, T.; Tanaka, H. K. M.; Tanaka, M.

    2010-02-01

    Cosmic-ray muon radiography is a method that is used to study the internal structure of volcanoes. We have developed a muon radiographic imaging board with a power consumption low enough to be powered by a small solar power system. The imaging board generates an angular distribution of the muons. Used for real-time reading, the method may facilitate the prediction of eruptions. For real-time observations, the Ethernet is employed, and the board works as a web server for a remote operation. The angular distribution can be obtained from a remote PC via a network using a standard web browser. We have collected and analyzed data obtained from a 3-day field study of cosmic-ray muons at a Satsuma-Iwojima volcano. The data provided a clear image of the mountain ridge as a cosmic-ray muon shadow. The measured performance of the system is sufficient for a stand-alone cosmic-ray muon radiography experiment.

  16. Built-in hyperspectral camera for smartphone in visible, near-infrared and middle-infrared lights region (third report): spectroscopic imaging for broad-area and real-time componential analysis system against local unexpected terrorism and disasters

    Hosono, Satsuki; Kawashima, Natsumi; Wollherr, Dirk; Ishimaru, Ichiro

    2016-05-01

    The distributed networks for information collection of chemical components with high-mobility objects, such as drones or smartphones, will work effectively for investigations, clarifications and predictions against unexpected local terrorisms and disasters like localized torrential downpours. We proposed and reported the proposed spectroscopic line-imager for smartphones in this conference. In this paper, we will mention the wide-area spectroscopic-image construction by estimating 6 DOF (Degrees Of Freedom: parallel movements=x,y,z and rotational movements=θx, θy, θz) from line data to observe and analyze surrounding chemical-environments. Recently, smartphone movies, what were photographed by peoples happened to be there, had worked effectively to analyze what kinds of phenomenon had happened around there. But when a gas tank suddenly blew up, we did not recognize from visible-light RGB-color cameras what kinds of chemical gas components were polluting surrounding atmospheres. Conventionally Fourier spectroscopy had been well known as chemical components analysis in laboratory usages. But volatile gases should be analyzed promptly at accident sites. And because the humidity absorption in near and middle infrared lights has very high sensitivity, we will be able to detect humidity in the sky from wide field spectroscopic image. And also recently, 6-DOF sensors are easily utilized for estimation of position and attitude for UAV (Unmanned Air Vehicle) or smartphone. But for observing long-distance views, accuracies of angle measurements were not sufficient to merge line data because of leverage theory. Thus, by searching corresponding pixels between line spectroscopic images, we are trying to estimate 6-DOF in high accuracy.

  17. Ion beam sputtered aluminum based multilayer mirrors for extreme ultraviolet solar imaging

    Ziani, A. [Laboratoire Charles Fabry, Institut d' Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 Palaiseau cedex France (France); Centre National d’Etudes Spatiales (CNES), 18 Avenue E. Belin, 31401 Toulouse (France); Delmotte, F., E-mail: Franck.Delmotte@InstitutOptique.fr [Laboratoire Charles Fabry, Institut d' Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 Palaiseau cedex France (France); Le Paven-Thivet, C. [Institut d' Electronique et de Télécommunications de Rennes (IETR) UMR-CNRS 6164, Université de Rennes 1, UEB, IUT Saint Brieuc, 18 rue Henri Wallon, 22004 Saint Brieuc cedex France (France); Meltchakov, E.; Jérome, A. [Laboratoire Charles Fabry, Institut d' Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 Palaiseau cedex France (France); Roulliay, M. [Institut des Sciences Moléculaires d’Orsay UMR 8214, Univ Paris Sud, 91405 Orsay France (France); Bridou, F. [Laboratoire Charles Fabry, Institut d' Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 Palaiseau cedex France (France); Gasc, K. [Centre National d’Etudes Spatiales (CNES), 18 Avenue E. Belin, 31401 Toulouse (France)

    2014-02-03

    In this paper, we report on the design, synthesis and characterization of extreme ultraviolet interferential mirrors for solar imaging applications in the spectral range 17 nm–34 nm. This research is carried out in the context of the preparation of the European Space Agency Solar Orbiter mission. The purpose of this study consists in optimizing the deposition of Al-based multilayers by ion beam sputtering according to several parameters such as the ion beam current and the sputtering angle. After optimization of Al thin films, several kinds of Al-based multilayer mirrors have been compared. We have deposited and characterized bi-material and also tri-material periodic multilayers: aluminum/molybdenum [Al/Mo], aluminum/molybdenum/boron carbide [Al/Mo/B{sub 4}C] and aluminum/molybdenum/silicon carbide [Al/Mo/SiC]. Best experimental results have been obtained on Al/Mo/SiC samples: we have measured reflectivity up to 48% at 17.3 nm and 27.5% at 28.2 nm on a synchrotron radiation source. - Highlights: • Design and synthesis of extreme ultraviolet interferential mirrors. • Optimization of aluminum thin films by adjusting several deposition parameters. • Comparison of results obtained with different types of Al-based multilayer mirrors. • Reflectivity up to 48% at 17.3 nm on a synchrotron radiation source.

  18. Ion beam sputtered aluminum based multilayer mirrors for extreme ultraviolet solar imaging

    Ziani, A.; Delmotte, F.; Le Paven-Thivet, C.; Meltchakov, E.; Jérome, A.; Roulliay, M.; Bridou, F.; Gasc, K.

    2014-01-01

    In this paper, we report on the design, synthesis and characterization of extreme ultraviolet interferential mirrors for solar imaging applications in the spectral range 17 nm–34 nm. This research is carried out in the context of the preparation of the European Space Agency Solar Orbiter mission. The purpose of this study consists in optimizing the deposition of Al-based multilayers by ion beam sputtering according to several parameters such as the ion beam current and the sputtering angle. After optimization of Al thin films, several kinds of Al-based multilayer mirrors have been compared. We have deposited and characterized bi-material and also tri-material periodic multilayers: aluminum/molybdenum [Al/Mo], aluminum/molybdenum/boron carbide [Al/Mo/B 4 C] and aluminum/molybdenum/silicon carbide [Al/Mo/SiC]. Best experimental results have been obtained on Al/Mo/SiC samples: we have measured reflectivity up to 48% at 17.3 nm and 27.5% at 28.2 nm on a synchrotron radiation source. - Highlights: • Design and synthesis of extreme ultraviolet interferential mirrors. • Optimization of aluminum thin films by adjusting several deposition parameters. • Comparison of results obtained with different types of Al-based multilayer mirrors. • Reflectivity up to 48% at 17.3 nm on a synchrotron radiation source

  19. An artificial neural network ensemble model for estimating global solar radiation from Meteosat satellite images

    Linares-Rodriguez, Alvaro; Ruiz-Arias, José Antonio; Pozo-Vazquez, David; Tovar-Pescador, Joaquin

    2013-01-01

    An optimized artificial neural network ensemble model is built to estimate daily global solar radiation over large areas. The model uses clear-sky estimates and satellite images as input variables. Unlike most studies using satellite imagery based on visible channels, our model also exploits all information within infrared channels of the Meteosat 9 satellite. A genetic algorithm is used to optimize selection of model inputs, for which twelve are selected – eleven 3-km Meteosat 9 channels and one clear-sky term. The model is validated in Andalusia (Spain) from January 2008 through December 2008. Measured data from 83 stations across the region are used, 65 for training and 18 independent ones for testing the model. At the latter stations, the ensemble model yields an overall root mean square error of 6.74% and correlation coefficient of 99%; the generated estimates are relatively accurate and errors spatially uniform. The model yields reliable results even on cloudy days, improving on current models based on satellite imagery. - Highlights: • Daily solar radiation data are generated using an artificial neural network ensemble. • Eleven Meteosat channels observations and a clear sky term are used as model inputs. • Model exploits all information within infrared Meteosat channels. • Measured data for a year from 83 ground stations are used. • The proposed approach has better performance than existing models on daily basis

  20. Automatic Detection and Evaluation of Solar Cell Micro-Cracks in Electroluminescence Images Using Matched Filters

    Spataru, Sergiu; Hacke, Peter; Sera, Dezso

    2016-11-21

    A method for detecting micro-cracks in solar cells using two dimensional matched filters was developed, derived from the electroluminescence intensity profile of typical micro-cracks. We describe the image processing steps to obtain a binary map with the location of the micro-cracks. Finally, we show how to automatically estimate the total length of each micro-crack from these maps, and propose a method to identify severe types of micro-cracks, such as parallel, dendritic, and cracks with multiple orientations. With an optimized threshold parameter, the technique detects over 90 % of cracks larger than 3 cm in length. The method shows great potential for quantifying micro-crack damage after manufacturing or module transportation for the determination of a module quality criterion for cell cracking in photovoltaic modules.

  1. Eddy current imaging for electrical characterization of silicon solar cells and TCO layers

    Hwang, Byungguk; Hillmann, Susanne; Schulze, Martin; Klein, Marcus; Heuer, Henning

    2015-03-01

    Eddy Current Testing has been mainly used to determine defects of conductive materials and wall thicknesses in heavy industries such as construction or aerospace. Recently, high frequency Eddy Current imaging technology was developed. This enables the acquirement of information of different depth level in conductive thin-film structures by realizing proper standard penetration depth. In this paper, we summarize the state of the art applications focusing on PV industry and extend the analysis implementing achievements by applying spatially resolved Eddy Current Testing. The specific state of frequency and complex phase angle rotation demonstrates diverse defects from front to back side of silicon solar cells and characterizes homogeneity of sheet resistance in Transparent Conductive Oxide (TCO) layers. In order to verify technical feasibility, measurement results from the Multi Parameter Eddy Current Scanner, MPECS are compared to the results from Electroluminescence.

  2. Simultaneous PET/MRI with (13)C magnetic resonance spectroscopic imaging (hyperPET): phantom-based evaluation of PET quantification.

    Hansen, Adam E; Andersen, Flemming L; Henriksen, Sarah T; Vignaud, Alexandre; Ardenkjaer-Larsen, Jan H; Højgaard, Liselotte; Kjaer, Andreas; Klausen, Thomas L

    2016-12-01

    Integrated PET/MRI with hyperpolarized (13)C magnetic resonance spectroscopic imaging ((13)C-MRSI) offers simultaneous, dual-modality metabolic imaging. A prerequisite for the use of simultaneous imaging is the absence of interference between the two modalities. This has been documented for a clinical whole-body system using simultaneous (1)H-MRI and PET but never for (13)C-MRSI and PET. Here, the feasibility of simultaneous PET and (13)C-MRSI as well as hyperpolarized (13)C-MRSI in an integrated whole-body PET/MRI hybrid scanner is evaluated using phantom experiments. Combined PET and (13)C-MRSI phantoms including a NEMA [(18)F]-FDG phantom, (13)C-acetate and (13)C-urea sources, and hyperpolarized (13)C-pyruvate were imaged repeatedly with PET and/or (13)C-MRSI. Measurements evaluated for interference effects included PET activity values in the largest sphere and a background region; total number of PET trues; and (13)C-MRSI signal-to-noise ratio (SNR) for urea and acetate phantoms. Differences between measurement conditions were evaluated using t tests. PET and (13)C-MRSI data acquisition could be performed simultaneously without any discernible artifacts. The average difference in PET activity between acquisitions with and without simultaneous (13)C-MRSI was 0.83 (largest sphere) and -0.76 % (background). The average difference in net trues was -0.01 %. The average difference in (13)C-MRSI SNR between acquisitions with and without simultaneous PET ranged from -2.28 to 1.21 % for all phantoms and measurement conditions. No differences were significant. The system was capable of (13)C-MRSI of hyperpolarized (13)C-pyruvate. Simultaneous PET and (13)C-MRSI in an integrated whole-body PET/MRI hybrid scanner is feasible. Phantom experiments showed that possible interference effects introduced by acquiring data from the two modalities simultaneously are small and non-significant. Further experiments can now investigate the benefits of simultaneous PET and

  3. MapX: An In Situ, Full-Frame X-Ray Spectroscopic Imager for the Biogenic Elements

    Blake, David; Sarrazin, Philippe; Thompson, Kathy; Bristow, Thomas

    2016-01-01

    Microbial life exploits microscale disequilibria at boundaries where valence, chemical potential, pH, Eh, etc. vary on a length scale commensurate with the organisms themselves - tens to hundreds of micrometers. These disequilibria can exist within cracks or veins in rocks and ice, at inter- or intra-crystalline boundaries, at sediment/water or sediment/atmosphere interfaces, or even within fluid inclusions trapped inside minerals. The detection of accumulations of the biogenic elements C,N,O,P,S at appropriate concentrations on or in a mineral/ice substrate would constitute permissive evidence of extant life, but context is also required. Does the putative biosignature exist in a habitable environment? Under what conditions of P, T, and chemical potential was the host mineralogy formed? MapX is an arm-deployed contact instrument that directly images the biogenic elements C, N, O, P, S, as well as the cations of the rock-forming minerals (Na, Mg, Al, Si, K, Ca, Ti, Cr, Mn, Fe) and important anions such as Cl, Fl. The instrument provides element images having =100 micron lateral spatial resolution over a 2.5 cm X 2.5 cm area, as well as quantitative XRF spectra from ground-selected or instrument-selected Regions of Interest (ROI) on the sample. Quantitative XRF spectra from ROI can be translated into mineralogies using ground- or instrument-based algorithms. Either an X-ray tube source (X-ray fluorescence) or a radioisotope source such as 244-Cm (alpha-particle and gamma-ray fluorescence) can be used, and characteristic X-rays emitted from the sample are imaged onto an X-ray sensitive CCD through an X-ray MicroPore Optic (MPO). As a fluorescent source, 244-Cm is highly desirable in a MapX instrument intended for life detection since high-energy alpha-particles are unrivaled in fluorescence yield for the low-Z elements. The MapX design as well as baseline performance requirements for a MapX instrument intended for life detection/identification of habitable

  4. Direct imaging of enhanced current collection on grain boundaries of Cu(In,Ga)Se{sub 2} solar cells

    Kim, JunHo, E-mail: jhk@incheon.ac.kr [Department of Physics, Incheon National University, Incheon 406-772 (Korea, Republic of); National Center for Photovoltaics, National Renewable Energy Laboratory (NREL), Golden, Colorado 80401 (United States); Kim, SeongYeon [Department of Physics, Incheon National University, Incheon 406-772 (Korea, Republic of); Jiang, Chun-Sheng; Ramanathan, Kannan; Al-Jassim, Mowafak M. [National Center for Photovoltaics, National Renewable Energy Laboratory (NREL), Golden, Colorado 80401 (United States)

    2014-02-10

    We report on direct imaging of current collection by performing conductive atomic force microscopy (C-AFM) measurement on a complete Cu(In,Ga)Se{sub 2} solar cell. The localized current was imaged by milling away the top conductive layer of the device by repeated C-AFM scans. The result exhibits enhanced photocurrent collection on grain boundaries (GBs) of CIGS films, consistent with the argument for electric-field-assisted carrier collection on the GBs.

  5. EUV high resolution imager on-board solar orbiter: optical design and detector performances

    Halain, J. P.; Mazzoli, A.; Rochus, P.; Renotte, E.; Stockman, Y.; Berghmans, D.; BenMoussa, A.; Auchère, F.

    2017-11-01

    The EUV high resolution imager (HRI) channel of the Extreme Ultraviolet Imager (EUI) on-board Solar Orbiter will observe the solar atmospheric layers at 17.4 nm wavelength with a 200 km resolution. The HRI channel is based on a compact two mirrors off-axis design. The spectral selection is obtained by a multilayer coating deposited on the mirrors and by redundant Aluminum filters rejecting the visible and infrared light. The detector is a 2k x 2k array back-thinned silicon CMOS-APS with 10 μm pixel pitch, sensitive in the EUV wavelength range. Due to the instrument compactness and the constraints on the optical design, the channel performance is very sensitive to the manufacturing, alignments and settling errors. A trade-off between two optical layouts was therefore performed to select the final optical design and to improve the mirror mounts. The effect of diffraction by the filter mesh support and by the mirror diffusion has been included in the overall error budget. Manufacturing of mirror and mounts has started and will result in thermo-mechanical validation on the EUI instrument structural and thermal model (STM). Because of the limited channel entrance aperture and consequently the low input flux, the channel performance also relies on the detector EUV sensitivity, readout noise and dynamic range. Based on the characterization of a CMOS-APS back-side detector prototype, showing promising results, the EUI detector has been specified and is under development. These detectors will undergo a qualification program before being tested and integrated on the EUI instrument.

  6. Modeling observations of solar coronal mass ejections with heliospheric imagers verified with the Heliophysics System Observatory.

    Möstl, C; Isavnin, A; Boakes, P D; Kilpua, E K J; Davies, J A; Harrison, R A; Barnes, D; Krupar, V; Eastwood, J P; Good, S W; Forsyth, R J; Bothmer, V; Reiss, M A; Amerstorfer, T; Winslow, R M; Anderson, B J; Philpott, L C; Rodriguez, L; Rouillard, A P; Gallagher, P; Nieves-Chinchilla, T; Zhang, T L

    2017-07-01

    We present an advance toward accurately predicting the arrivals of coronal mass ejections (CMEs) at the terrestrial planets, including Earth. For the first time, we are able to assess a CME prediction model using data over two thirds of a solar cycle of observations with the Heliophysics System Observatory. We validate modeling results of 1337 CMEs observed with the Solar Terrestrial Relations Observatory (STEREO) heliospheric imagers (HI) (science data) from 8 years of observations by five in situ observing spacecraft. We use the self-similar expansion model for CME fronts assuming 60° longitudinal width, constant speed, and constant propagation direction. With these assumptions we find that 23%-35% of all CMEs that were predicted to hit a certain spacecraft lead to clear in situ signatures, so that for one correct prediction, two to three false alarms would have been issued. In addition, we find that the prediction accuracy does not degrade with the HI longitudinal separation from Earth. Predicted arrival times are on average within 2.6 ± 16.6 h difference of the in situ arrival time, similar to analytical and numerical modeling, and a true skill statistic of 0.21. We also discuss various factors that may improve the accuracy of space weather forecasting using wide-angle heliospheric imager observations. These results form a first-order approximated baseline of the prediction accuracy that is possible with HI and other methods used for data by an operational space weather mission at the Sun-Earth L5 point.

  7. MapX An In Situ, Full-frame X-Ray Spectroscopic Imager for Planetary Science and Astrobiology

    Blake, David; Sarrazin, Philippe; Thompson, Kathleen; Bristow, Thomas

    2017-01-01

    Microbial life exploits micron-scale disequilibria at boundaries where valence, chemical potential, pH, Eh, etc. vary on a length scale commensurate with the organisms - 10's to 100's of microns. The detection of accumulations of the biogenic elements C,N,O,P,S at appropriate concentrations on or in a mineral/ice substrate would constitute permissive evidence of extant life, but context is also required. Does the putative biosignature exist under habitable conditions? Under what conditions of P, T, and chemical potential was the host mineralogy formed? MapX is an in situ robotic spacecraft instrument that images the biogenic elements C, N, O, P, S, as well as the cations of the rock-forming minerals (Na, Mg, Al, Si, K, Ca, Ti, Cr, Mn, Fe) and important anions such as Cl, Fl. MapX provides element maps with less than or equal to100 microns resolution over a 2.5 cm X 2.5 cm area, as well as quantitative XRF spectra from ground- or instrument-selected Regions of Interest (ROI). XRF spectra are converted to mineralogies using ground- or instrument-based algorithms. Either X-ray tube or radioisotope sources such as 244Cm (Alpha-particle and gamma- ray fluorescence) can be used. Fluoresced sample Xrays are imaged onto an X-ray sensitive CCD through an X-ray MicroPore Optic (MPO). The MapX design as well as baseline performance requirements for a MapX instrument intended for life detection / identification of habitable environments will be presented.

  8. Application of photoluminescence imaging and laser-beam-induced-current mapping in thin film solar cell characterization

    Liu, Geyuan [Iowa State Univ., Ames, IA (United States)

    2017-05-06

    My research projects are focused on application of photonics, optics and micro- fabrication technology in energy related fields. Photonic crystal fabrication research has the potential to help us generate and use light more efficiently. In order to fabricate active 3D woodpile photonic structure devices, a woodpile template is needed to enable the crystal growth process. We developed a silica woodpile template fabrication process based on two polymer transfer molding technique. A silica woodpile template is demonstrated to work with temperature up to 900 C. It provides a more economical way to explore making better 3D active woodpile photonic devices like 3D photonic light emitting diodes (LED). Optical research on solar cell testing has the potential to make our energy generation more e cient and greener. PL imaging and LBIC mapping are used to measure CdTe solar cells with different back contacts. A strong correlation between PL image defects and LBIC map defects is observed. This opens up potential application for PL imaging in fast solar cell inspection. 2D laser IV scan shows its usage in 2D parameter mapping. We show its ability to generate important information about solar cell performance locally around PL image defects.

  9. Imaging spectroscopy of type U and J solar radio bursts with LOFAR

    Reid, Hamish A. S.; Kontar, Eduard P.

    2017-10-01

    Context. Radio U-bursts and J-bursts are signatures of electron beams propagating along magnetic loops confined to the corona. The more commonly observed type III radio bursts are signatures of electron beams propagating along magnetic loops that extend into interplanetary space. Given the prevalence of solar magnetic flux to be closed in the corona, why type III bursts are more frequently observed than U-bursts or J-bursts is an outstanding question. Aims: We use Low-Frequency Array (LOFAR) imaging spectroscopy between 30-80 MHz of low-frequency U-bursts and J-bursts, for the first time, to understand why electron beams travelling along coronal loops produce radio emission less often. Radio burst observations provide information not only about the exciting electron beams but also about the structure of large coronal loops with densities that are too low for standard extreme ultraviolet (EUV) or X-ray analysis. Methods: We analysed LOFAR images of a sequence of two J-bursts and one U-burst. The different radio source positions were used to model the spatial structure of the guiding magnetic flux tube and then deduce the energy range of the exciting electron beams without the assumption of a standard density model. We also estimated the electron density along the magnetic flux rope and compared it to coronal models. Results: The radio sources infer a magnetic loop that is 1 solar radius in altitude with the highest frequency sources starting around 0.6 solar radii. Electron velocities were found between 0.13 c and 0.24 c with the front of the electron beam travelling faster than the back of the electron beam. The velocities correspond to energy ranges within the beam from 0.7-11 keV to 0.7-43 keV. The density along the loop is higher than typical coronal density models and the density gradient is smaller. Conclusions: We found that a more restrictive range of accelerated beam and background plasma parameters can result in U-bursts or J-bursts, causing type III

  10. Solar flares observed simultaneously with SphinX, GOES and RHESSI

    Mrozek, Tomasz; Gburek, Szymon; Siarkowski, Marek; Sylwester, Barbara; Sylwester, Janusz; Kępa, Anna; Gryciuk, Magdalena

    2013-07-01

    In February 2009, during recent deepest solar minimum, Polish Solar Photometer in X-rays (SphinX) begun observations of the Sun in the energy range of 1.2-15 keV. SphinX was almost 100 times more sensitive than GOES X-ray Sensors. The silicon PIN diode detectors used in the experiment were carefully calibrated on the ground using Synchrotron Radiation Source BESSY II. The SphinX energy range overlaps with the Ramaty High Energy Solar Spectroscopic Imager (RHESSI) energy range. The instrument provided us with observations of hundreds of very small flares and X-ray brightenings. We have chosen a group of solar flares observed simultaneously with GOES, SphinX and RHESSI and performed spectroscopic analysis of observations wherever possible. The analysis of thermal part of the spectra showed that SphinX is a very sensitive complementary observatory for RHESSI and GOES.

  11. Biomedical Applications of Mid-Infrared Spectroscopic Imaging and Multivariate Data Analysis: Contribution to the Understanding of Diabetes Pathogenesis

    Aboualizadeh, Ebrahim

    Diabetic retinopathy (DR) is a microvascular complication of diabetes and a leading cause of adult vision loss. Although a great deal of progress has been made in ophthalmological examinations and clinical approaches to detect the signs of retinopathy in patients with diabetes, there still remain outstanding questions regarding the molecular and biochemical changes involved. To discover the biochemical mechanisms underlying the development and progression of changes in the retina as a result of diabetes, a more comprehensive understanding of the bio-molecular processes, in individual retinal cells subjected to hyperglycemia, is required. Animal models provide a suitable resource for temporal detection of the underlying pathophysiological and biochemical changes associated with DR, which is not fully attainable in human studies. In the present study, I aimed to determine the nature of diabetes-induced, highly localized biochemical changes in the retinal tissue from Ins2Akita/+ (Akita/+; a model of Type I diabetes) male mice with different duration of diabetes. Employing label-free, spatially resolved Fourier transform infrared (FT-IR) imaging engaged with chemometric tools enabled me to identify temporal-dependent reproducible biomarkers of the diabetic retinal tissue from mice with 6 or 12 weeks, and 6 or 10 months of diabetes. I report, for the first time, the origin of molecular changes in the biochemistry of individual retinal layers with different duration of diabetes. A robust classification between distinctive retinal layers - namely photoreceptor layer (PRL), outer plexiform layer (OPL), inner nuclear layer (INL), and inner plexiform layer (IPL) - and associated temporal-dependent spectral biomarkers, were delineated. Spatially-resolved super resolution chemical images revealed oxidative stress-induced structural and morphological alterations within the nucleus of the photoreceptors. Comparison among the PRL, OPL, INL, and IPL suggested that the

  12. TH-AB-209-05: Validating Hemoglobin Saturation and Dissolved Oxygen in Tumors Using Photoacoustic Computed Tomographic Spectroscopic Imaging

    Burnett, J; Sick, J; Liu, B [Purdue University, West Lafayette, IN (United States); Cao, N [University of Washington Medical Center, Seattle, WA (United States); Nakshatri, H; Mendonca, M [Indiana University - Purdue University Indianapolis, Indianapolis, IN (United States); Stantz, K [Purdue University, West Lafayette, IN (United States); Indiana University - Purdue University Indianapolis, Indianapolis, IN (United States)

    2016-06-15

    Purpose: Photoacoustic computed tomographic spectroscopy (PCT-S) provides intra-tumor measurements of oxygenation with high spatial resolution (0.2mm) and temporal fidelity (1–2 minutes) without the need for exogenous agents or ionizing radiation, thus providing a unique in vivo assay to measure SaO{sub 2} and investigate acute and chronic forms of hypoxia. The goal of this study is to validate in vivo SaO{sub 2} levels within tail artery of mice and the relationship between SaO{sub 2} and pO{sub 2} within subcutaneous breast tumors using PCT-S imaging, pulse oximetry and an OxyLite probe. Methods: A closed circuit phantom was fabricated to control blood oxygenation levels, where SaO{sub 2} was measured using a co-oximeter and pO{sub 2} using an Oxylite probe. Next, SaO{sub 2} levels within the tail arteries of mice (n=3) were measured using PCT-S and pulse oximetry while breathing high-to-low oxygen levels (6-cycles). Finally, PCT-S was used to measure SaO{sub 2} levels in MCF-7, MCF-7-VEGF165, and MDA-MB-231 xenograft breast tumors and compared to Oxylite pO{sub 2} levels values. Results: SaO{sub 2} and pO{sub 2} data obtained from the calibration phantom was fit to Hill’s equation: aO{sub 2} levels between 88 and 52% demonstrated a linear relationship (r2=0.96) and a 3.2% uncertainty between PCT-S values relative to pulse oximetry. Scatter plots of localized PCT-S measured SaO2 and Oxylite pO{sub 2} levels in MCF-7/MCF-7-VEGF165 and MDA-MD-231 breast tumors were fit to Hill’s equation: P50=17.2 and 20.7mmHg, and n=1.76 and 1.63. These results are consistent with sigmoidal form of Hill’s equation, where the lower P{sub 50} value is indicative of an acidic tumor microenvironment. Conclusion: The results demonstrate photoacoustic imaging can be used to measure SaO{sub 2} cycling and intra-tumor oxygenation, and provides a powerful in vivo assay to investigate the role of hypoxia in radiation, anti-angiogenic, and immunotherapies.

  13. Photoanode Thickness Optimization and Impedance Spectroscopic Analysis of Dye-Sensitized Solar Cells based on a Carbazole-Containing Ruthenium Dye

    Choi, Jongwan; Kim, Felix Sunjoo

    2018-03-01

    We studied the influence of photoanode thickness on the photovoltaic characteristics and impedance responses of the dye-sensitized solar cells based on a ruthenium dye containing a hexyloxyl-substituted carbazole unit (Ru-HCz). As the thickness of photoanode increases from 4.2 μm to 14.8 μm, the dye-loading amount and the efficiency increase. The device with thicker photoanode shows a decrease in the efficiency due to the higher probability of recombination of electron-hole pairs before charge extraction. We also analyzed the electron-transfer and recombination characteristics as a function of photoanode thickness through detailed electrochemical impedance spectroscopy analysis.

  14. 1H MR spectroscopic imaging in patients with MRI-negative extratemporal epilepsy: correlation with ictal onset zone and histopathology

    Krsek, Pavel; Komarek, Vladimir; Hajek, Milan; Dezortova, Monika; Jiru, Filip; Skoch, Antonin; Marusic, Petr; Zamecnik, Josef; Kyncl, Martin; Tichy, Michal

    2007-01-01

    Proton magnetic resonance spectroscopy ( 1 H MRS) is beneficial in the lateralization of the epileptogenic zone in temporal lobe epilepsy; however, its role in extratemporal and, especially, MRI-negative epilepsy has not been established. This study seeks to verify how 1 H MRS could help in localizing the epileptogenic zone in patients with MRI-negative extratemporal epilepsy. Seven patients (8-23 years) with MRI-negative refractory focal epilepsy were studied using 1 H MRS on a 1.5T MR system. Chemical shift imaging sequence in the transversal plane was directed towards the suspected epileptogenic zone localized by seizure semiology, scalp video/EEG, ictal SPECT and 18 FDG-PET. Spectra were evaluated using the program CULICH, and the coefficient of asymmetry was used for quantitative lateralization. MRS detected lateralization in all patients and was able to localize pathology in five. The most frequent findings were decreased ratios of N-acetylaspartate to choline compounds characterized by increasing choline concentration. The localization of the 1 H MRS abnormality correlated well with ictal SPECT and subdural mapping. In all cases, histopathological analysis revealed MRI-undetected focal cortical dysplasias. 1 H MRS could be more sensitive for the detection of discrete malformations of cortical development than conventional MRI. It is valuable in the presurgical evaluation of patients without MRI-apparent lesions. (orig.)

  15. STAR FORMATION PROPERTIES IN BARRED GALAXIES (SFB). I. ULTRAVIOLET TO INFRARED IMAGING AND SPECTROSCOPIC STUDIES OF NGC 7479

    Zhou Zhimin; Meng Xianmin; Wu Hong; Cao Chen

    2011-01-01

    Large-scale bars and minor mergers are important drivers for the secular evolution of galaxies. Based on ground-based optical images and spectra as well as ultraviolet data from the Galaxy Evolution Explorer and infrared data from the Spitzer Space Telescope, we present a multi-wavelength study of star formation properties in the barred galaxy NGC 7479, which also has obvious features of a minor merger. Using various tracers of star formation, we find that under the effects of both a stellar bar and a minor merger, star formation activity mainly takes place along the galactic bar and arms, while the star formation rate changes from the bar to the disk. With the help of spectral synthesis, we find that strong star formation took place in the bar region about 100 Myr ago, and the stellar bar might have been ∼10 Gyr old. By comparing our results with the secular evolutionary scenario from Jogee et al., we suggest that NGC 7479 is possibly in a transitional stage of secular evolution at present, and it may eventually become an earlier type galaxy or a luminous infrared galaxy. We also note that the probable minor merger event happened recently in NGC 7479, and we find two candidates for minor merger remnants.

  16. The DEPFET detector-amplifier structure for spectroscopic imaging in astronomy and for experiments at free electron lasers

    Lutz, G., E-mail: gerhard.lutz@pnsensor.de; Aschauer, S.; Majewski, P.; Holl, P.; Strüder, L.

    2017-02-11

    The DEPFET detector-amplifier structure possesses several unique properties which make it extremely useful as readout element in semiconductor detectors and in particular as building block of semiconductor pixel detectors. Variations of DEPFETs can be tuned to specific requirements as to be sensitive only in predetermined time intervals, to measure signal charge with sub-electron precision, dead-time-free readout and with signal compression. These devices have been shown to work in simulations and in prototypes. Recently the first two fully developed detector systems have been finished and installed in the MIXS (Mercury Image X-ray Spectrometer) instrument of the Mercury Planetary Orbiter scheduled to be launched in 2017. A further DEPFET detector system under development is the DSSC (Depfet Sensor with Signal Compression) that will be installed in one of the beam-lines of XFEL. The requirements of the two projects are rather different. While the MIXS sensors are supposed to measure precisely the energy and position of single photons down to very low energies but at moderate rates, the DSSC has to measure the number of photons arriving in each pixel within a time interval of 220 ns. Here the challenge is the capability of detecting single X-ray photons in one pixel simultaneously with up to 10,000 photons in some other pixels. Device functioning has been verified with sensors produced in a research laboratory. Now process and design have been adapted to an industrial type production line, allowing additional improvements.

  17. Bio-Spectroscopic Imaging Provides Evidence of Hippocampal Zn Deficiency and Decreased Lipid Unsaturation in an Accelerated Ageing Mouse Model.

    Fimognari, Nicholas; Hollings, Ashley; Lam, Virginie; Tidy, Rebecca J; Kewish, Cameron M; Albrecht, Matthew A; Takechi, Ryu; Mamo, John C L; Hackett, Mark J

    2018-06-14

    Western society is facing a health epidemic due to the increasing incidence of dementia in ageing populations, and there are still few effective diagnostic methods, minimal treatment options, and no cure. Ageing is the greatest risk factor for memory loss that occurs during the natural ageing process, as well as being the greatest risk factor for neurodegenerative disease such as Alzheimer's disease. Therefore, greater understanding of the biochemical pathways that drive a healthy ageing brain towards dementia (pathological ageing or Alzheimer's disease), is required to accelerate the development of improved diagnostics and therapies. Unfortunately, many animal models of dementia model chronic amyloid precursor protein over-expression, which although highly relevant to mechanisms of amyloidosis and familial Alzheimer's disease, does not model well dementia during the natural ageing process. A promising animal model reported to model mechanisms of accelerated natural ageing and memory impairments, is the senescence accelerated murine prone strain 8 (SAMP8), which has been adopted by many research group to study the biochemical transitions that occur during brain ageing. A limitation to traditional methods of biochemical characterisation is that many important biochemical and elemental markers (lipid saturation, lactate, transition metals) cannot be imaged at meso- or micro-spatial resolution. Therefore, in this investigation we report the first multi-modal biospectroscopic characterisation of the SAMP8 model, and have identified important biochemical and elemental alterations, and co-localisations, between 4 month old SAMP8 mice and the relevant control (SAMR1) mice. Specifically, we demonstrate direct evidence of altered metabolism and disturbed lipid homeostasis within corpus callosum white matter, in addition to localised hippocampal metal deficiencies, in the accelerated ageing phenotype. Such findings have important implication for future research aimed at

  18. Toward 3-D E-field visualization in laser-produced plasma by polarization-spectroscopic imaging

    Kim, Yong W.

    2004-01-01

    A 3-D volume radiator such as laser-produced plasma (LPP) plumes is observed in the form of a 2-D projection of its radiative structure. The traditional approach to 3-D structure reconstruction relies on multiple projections but is not suitable as a general method for unsteady radiating objects. We have developed a general method for 3-D structure reconstruction for LPP plumes in stages of increasing complexity. We have chosen neutral gas-confined LPP plumes from an aluminum target immersed in high-density argon because the plasma experiences Rayleigh-Taylor instability. We make use of two time-resolved, mutually orthogonal side views of a LPP plume and a front-view snapshot. No symmetry assumptions are needed. Two scaling relations are invoked that connects the plasma temperature and pressure to local specific intensity at selected wavelength(s). Two mutually-orthogonal lateral luminosity views of the plume at each known distance from the target surface are compared with those computed from the trial specific intensity profiles and the scaling relations. The luminosity error signals are minimized to find the structure. The front-view snapshot is used to select the initial trial profile and as a weighting function for allocation of the error signal into corrections for specific intensities from the plasma cells along the line of sight. Full Saha equilibrium for multiple stages of ionization is treated, together with the self-absorption, in the computation of the luminosity. We show the necessary optics for determination of local electric fields through polarization-resolved imaging. (author)

  19. Imaging Flash Lidar for Safe Landing on Solar System Bodies and Spacecraft Rendezvous and Docking

    Amzajerdian, Farzin; Roback, Vincent E.; Bulyshev, Alexander E.; Brewster, Paul F.; Carrion, William A; Pierrottet, Diego F.; Hines, Glenn D.; Petway, Larry B.; Barnes, Bruce W.; Noe, Anna M.

    2015-01-01

    NASA has been pursuing flash lidar technology for autonomous, safe landing on solar system bodies and for automated rendezvous and docking. During the final stages of the landing from about 1 kilometer to 500 meters above the ground, the flash lidar can generate 3-Dimensional images of the terrain to identify hazardous features such as craters, rocks, and steep slopes. The onboard flight computer can then use the 3-D map of terrain to guide the vehicle to a safe location. As an automated rendezvous and docking sensor, the flash lidar can provide relative range, velocity, and bearing from an approaching spacecraft to another spacecraft or a space station. NASA Langley Research Center has developed and demonstrated a flash lidar sensor system capable of generating 16,000 pixels range images with 7 centimeters precision, at 20 Hertz frame rate, from a maximum slant range of 1800 m from the target area. This paper describes the lidar instrument and presents the results of recent flight tests onboard a rocket-propelled free-flyer vehicle (Morpheus) built by NASA Johnson Space Center. The flights were conducted at a simulated lunar terrain site, consisting of realistic hazard features and designated landing areas, built at NASA Kennedy Space Center specifically for this demonstration test. This paper also provides an overview of the plan for continued advancement of the flash lidar technology aimed at enhancing its performance to meet both landing and automated rendezvous and docking applications.

  20. The combined use of conventional MRI and MR spectroscopic imaging increases the diagnostic accuracy in amyotrophic lateral sclerosis

    Cervo, Amedeo [Department of Advanced Biomedical Sciences, University “Federico II”, Naples (Italy); Cocozza, Sirio, E-mail: siriococozza@hotmail.it [Department of Advanced Biomedical Sciences, University “Federico II”, Naples (Italy); Saccà, Francesco [Department of Neurosciences, Reproductive Sciences and Odontostomatology, University “Federico II”, Naples (Italy); Giorgio, Sara M.d.A. [Department of Advanced Biomedical Sciences, University “Federico II”, Naples (Italy); Morra, Vincenzo Brescia [Department of Neurosciences, Reproductive Sciences and Odontostomatology, University “Federico II”, Naples (Italy); Tedeschi, Enrico [Department of Advanced Biomedical Sciences, University “Federico II”, Naples (Italy); Marsili, Angela; Vacca, Giovanni [Department of Neurosciences, Reproductive Sciences and Odontostomatology, University “Federico II”, Naples (Italy); Palma, Vincenzo [U.O.C. Neurofisiopatologia, PO S. Gennaro ASL Napoli 1, Naples (Italy); Brunetti, Arturo [Department of Advanced Biomedical Sciences, University “Federico II”, Naples (Italy); Quarantelli, Mario [Biostructure and Bioimaging Institute, National Research Council, Naples (Italy)

    2015-01-15

    Highlights: • We assessed in ALS the diagnostic accuracy of MRI signal and MRS data used alone and in combination. • We found that T2-hypointensity and NAA decrease in motor cortex are two independent phenomena. • These two variables taken alone do not provide acceptable diagnostic accuracy in ALS. • The same variables, when used in combination, improve the diagnostic accuracy of MRI in ALS. - Abstract: Purpose: We aimed to assess, in amyotrophic lateral sclerosis (ALS), the diagnostic accuracy of the combined use of conventional MRI signal changes (namely, hypointensity of the precentral cortex and hyperintensity of the corticospinal tracts on T2-weighted images), and N-Acetyl-Aspartate (NAA) reduction in the motor cortex at Magnetic Resonance Spectroscopy (MRS), which are affected by limited diagnostic accuracy when used separately. Methods: T2-hypointensity and NAA/(Choline + Creatine) ratio of the precentral gyrus and T2-hyperintensity of the corticospinal tracts were measured in 84 ALS patients and 28 healthy controls, using a Region-of-Interest approach. Sensitivity and specificity values were calculated using Fisher stepwise discriminant analysis, and cross-validated using the leave-one-out method. Results: Precentral gyrus T2 signal intensity (p < 10{sup −4}) and NAA peak (p < 10{sup −6}) were significantly reduced in patients, and their values did not correlate significantly to each other both in patients and controls, while no significant differences were obtained in terms of T2-hyperintensity of the corticospinal tract. Sensitivity and specificity of the two discriminant variables, taken alone, were 71.4% and 75.0%, for NAA peak, and 63.1% and 71.4% for T2-hypointensity, respectively. When using these two variables in combination, a significant increase in sensitivity (78.6%) and specificity (82.1%) was achieved. Conclusions: Precentral gyrus T2-hypointensity and NAA peak are not significantly correlated in ALS patients, suggesting that they

  1. The combined use of conventional MRI and MR spectroscopic imaging increases the diagnostic accuracy in amyotrophic lateral sclerosis

    Cervo, Amedeo; Cocozza, Sirio; Saccà, Francesco; Giorgio, Sara M.d.A.; Morra, Vincenzo Brescia; Tedeschi, Enrico; Marsili, Angela; Vacca, Giovanni; Palma, Vincenzo; Brunetti, Arturo; Quarantelli, Mario

    2015-01-01

    Highlights: • We assessed in ALS the diagnostic accuracy of MRI signal and MRS data used alone and in combination. • We found that T2-hypointensity and NAA decrease in motor cortex are two independent phenomena. • These two variables taken alone do not provide acceptable diagnostic accuracy in ALS. • The same variables, when used in combination, improve the diagnostic accuracy of MRI in ALS. - Abstract: Purpose: We aimed to assess, in amyotrophic lateral sclerosis (ALS), the diagnostic accuracy of the combined use of conventional MRI signal changes (namely, hypointensity of the precentral cortex and hyperintensity of the corticospinal tracts on T2-weighted images), and N-Acetyl-Aspartate (NAA) reduction in the motor cortex at Magnetic Resonance Spectroscopy (MRS), which are affected by limited diagnostic accuracy when used separately. Methods: T2-hypointensity and NAA/(Choline + Creatine) ratio of the precentral gyrus and T2-hyperintensity of the corticospinal tracts were measured in 84 ALS patients and 28 healthy controls, using a Region-of-Interest approach. Sensitivity and specificity values were calculated using Fisher stepwise discriminant analysis, and cross-validated using the leave-one-out method. Results: Precentral gyrus T2 signal intensity (p < 10 −4 ) and NAA peak (p < 10 −6 ) were significantly reduced in patients, and their values did not correlate significantly to each other both in patients and controls, while no significant differences were obtained in terms of T2-hyperintensity of the corticospinal tract. Sensitivity and specificity of the two discriminant variables, taken alone, were 71.4% and 75.0%, for NAA peak, and 63.1% and 71.4% for T2-hypointensity, respectively. When using these two variables in combination, a significant increase in sensitivity (78.6%) and specificity (82.1%) was achieved. Conclusions: Precentral gyrus T2-hypointensity and NAA peak are not significantly correlated in ALS patients, suggesting that they reflect

  2. Imaging the Anomalous Charge Distribution Inside CsPbBr3 Perovskite Quantum Dots Sensitized Solar Cells.

    Panigrahi, Shrabani; Jana, Santanu; Calmeiro, Tomás; Nunes, Daniela; Martins, Rodrigo; Fortunato, Elvira

    2017-10-24

    Highly luminescent CsPbBr 3 perovskite quantum dots (QDs) have gained huge attention in research due to their various applications in optoelectronics, including as a light absorber in photovoltaic solar cells. To improve the performances of such devices, it requires a deeper knowledge on the charge transport dynamics inside the solar cell, which are related to its power-conversion efficiency. Here, we report the successful fabrication of an all-inorganic CsPbBr 3 perovskite QD sensitized solar cell and the imaging of anomalous electrical potential distribution across the layers of the cell under different illuminations using Kelvin probe force microscopy. Carrier generation, separation, and transport capacity inside the cells are dependent on the light illumination. Large differences in surface potential between electron and hole transport layers with unbalanced carrier separation at the junction have been observed under white light (full solar spectrum) illumination. However, under monochromatic light (single wavelength of solar spectrum) illumination, poor charge transport occurred across the junction as a consequence of less difference in surface potential between the active layers. The outcome of this study provides a clear idea on the carrier dynamic processes inside the cells and corresponding surface potential across the layers under the illumination of different wavelengths of light to understand the functioning of the solar cells and ultimately for the improvement of their photovoltaic performances.

  3. Physiological neuronal decline in healthy aging human brain - An in vivo study with MRI and short echo-time whole-brain (1)H MR spectroscopic imaging.

    Ding, Xiao-Qi; Maudsley, Andrew A; Sabati, Mohammad; Sheriff, Sulaiman; Schmitz, Birte; Schütze, Martin; Bronzlik, Paul; Kahl, Kai G; Lanfermann, Heinrich

    2016-08-15

    Knowledge of physiological aging in healthy human brain is increasingly important for neuroscientific research and clinical diagnosis. To investigate neuronal decline in normal aging brain eighty-one healthy subjects aged between 20 and 70years were studied with MRI and whole-brain (1)H MR spectroscopic imaging. Concentrations of brain metabolites N-acetyl-aspartate (NAA), choline (Cho), total creatine (tCr), myo-inositol (mI), and glutamine+glutamate (Glx) in ratios to internal water, and the fractional volumes of brain tissue were estimated simultaneously in eight cerebral lobes and in cerebellum. Results demonstrated that an age-related decrease in gray matter volume was the largest contribution to changes in brain volume. Both lobar NAA and the fractional volume of gray matter (FVGM) decreased with age in all cerebral lobes, indicating that the decreased NAA was predominantly associated with decreased gray matter volume and neuronal density or metabolic activity. In cerebral white matter Cho, tCr, and mI increased with age in association with increased fractional volume, showing altered cellular membrane turn-over, energy metabolism, and glial activity in human aging white matter. In cerebellum tCr increased while brain tissue volume decreased with age, showing difference to cerebral aging. The observed age-related metabolic and microstructural variations suggest that physiological neuronal decline in aging human brain is associated with a reduction of gray matter volume and neuronal density, in combination with cellular aging in white matter indicated by microstructural alterations and altered energy metabolism in the cerebellum. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Short-echo 3D H-1 Magnetic Resonance Spectroscopic Imaging of patients with glioma at 7T for characterization of differences in metabolite levels

    Li, Yan; Larson, Peder; Chen, Albert P.; Lupo, Janine M.; Ozhinsky, Eugene; Kelley, Douglas; Chang, Susan M.; Nelson, Sarah J.

    2014-01-01

    Purpose The purpose of this study was to evaluate the feasibility of using a short echo time, 3D H-1 magnetic resonance spectroscopic imaging (MRSI) sequence at 7T to assess the metabolic signature of lesions for patients with glioma. Materials and Methods 29 patients with glioma were studied. MRSI data were obtained using CHESS water suppression, spectrally-selective adiabatic inversion-recovery pulses and automatically prescribed outer-volume-suppression for lipid suppression, and spin echo slice selection (TE=30ms). An interleaved flyback echo-planar trajectory was applied to shorten the total acquisition time (~10min). Relative metabolite ratios were estimated in tumor and in normal-appearing white and gray matter (NAWM, GM). Results Levels of glutamine, myo-inositol, glycine and glutathione relative to total creatine (tCr) were significantly increased in the T2 lesions for all tumor grades compared to those in the NAWM (p < 0.05), while N-acetyl aspartate to tCr were significantly decreased (p < 0.05). In grade 2 gliomas, level of total choline-containing-compounds to tCr was significantly increased (p = 0.0137), while glutamate to tCr was significantly reduced (p = 0.0012). Conclusion The improved sensitivity of MRSI and the increased number of metabolites that can be evaluated using 7T MR scanners is of interest for evaluating patients with glioma. This study has successfully demonstrated the application of a short-echo spin-echo MRSI sequence to detect characteristic differences in regions of tumor versus normal appearing brain. PMID:24935758

  5. Design and Ground Calibration of the Helioseismic and Magnetic Imager (HMI) Instrument on the Solar Dynamics Observatory (SDO)

    Schou, J.; Scherrer, P. H.; Bush, R. I.; Wachter, R.; Couvidat, S.; Rabello-Soares, M. C.; Bogart, R. S.; Hoeksema, J. T.; Liu, Y.; Duvall, T. L., Jr.; hide

    2012-01-01

    The Helioseismic and Magnetic Imager (HMI) investigation will study the solar interior using helioseismic techniques as well as the magnetic field near the solar surface. The HMI instrument is part of the Solar Dynamics Observatory (SDO) that was launched on 11 February 2010. The instrument is designed to measure the Doppler shift, intensity, and vector magnetic field at the solar photosphere using the 6173 Fe I absorption line. The instrument consists of a front-window filter, a telescope, a set of wave plates for polarimetry, an image-stabilization system, a blocking filter, a five-stage Lyot filter with one tunable element, two wide-field tunable Michelson interferometers, a pair of 4096(exo 2) pixel cameras with independent shutters, and associated electronics. Each camera takes a full-disk image roughly every 3.75 seconds giving an overall cadence of 45 seconds for the Doppler, intensity, and line-of-sight magnetic-field measurements and a slower cadence for the full vector magnetic field. This article describes the design of the HMI instrument and provides an overview of the pre-launch calibration efforts. Overviews of the investigation, details of the calibrations, data handling, and the science analysis are provided in accompanying articles.

  6. Venus: cloud level circulation during 1982 as determined from Pioneer cloud photopolarimeter images. 11. Solar longitude dependent circulation

    Limaye, S.S.

    1988-01-01

    Pioneer Venus Orbiter images obtained in 1982 indicate a marked solar-locked dependence of cloud level circulation in both averaged cloud motions and cloud layer UV reflectivity. An apparent relationship is noted between horizontal divergence and UV reflectivity: the highest reflectivities are associated with regions of convergence at high latitudes, while lower values are associated with equatorial latitude regions where the motions are divergent. In solar-locked coordinates, the rms deviation of normalized UV brightness is higher at 45-deg latitudes than in equatorial regions. 37 references

  7. Monodeuterated methane in the outer solar system. I. Spectroscopic analysis of the bands at 1.55 and 1.95 microns

    Lutz, B.L.; de Bergh, C.; Maillard, J.P.

    1983-01-01

    The analysis of the near-infrared spectrum of monodeuterated methane (CH 3 D) near 6400 cm -1 and 5100 cm -1 is presented as the first of a series of papers dealing with laboratory studies of this molecule and with observational searches for it in outer solar system objects. Three new parallel bands which have locally perturbed upper states connecting with the ground state are identified, and approximate rotational constants are derived. The band centered near 6425 cm -1 and the 9613 A band previously analyzed by Lutz, Danehy, and Ramsay are found to form an apparent vibrational progression with the ν 2 fundamental at 2200 cm -1 , and vibrational assignments of 3ν 2 and 5ν 2 , respectively, are proposed. Detailed comparison of the rotational constants of the states involved is shown to support these assignments

  8. Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas

    Server, Andres; Kulle, Bettina; Gadmar, Oystein B.; Josefsen, Roger; Kumar, Theresa; Nakstad, Per H.

    2011-01-01

    Purpose: Tumor grading is very important both in treatment decision and evaluation of prognosis. While tissue samples are obtained as part of most therapeutic approaches, factors that may result in inaccurate grading due to sampling error (namely, heterogeneity in tissue sampling, as well as tumor-grade heterogeneity within the same tumor specimen), have led to a desire to use imaging better to ascertain tumor grade. The purpose in our study was to evaluate the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), area under the curve (AUC), and accuracy of diffusion-weighted MR imaging (DWI), proton MR spectroscopic imaging (MRSI) or both in grading primary cerebral gliomas. Materials and methods: We performed conventional MR imaging (MR), DWI, and MRSI in 74 patients with newly diagnosed brain gliomas: 59 patients had histologically verified high-grade gliomas: 37 glioblastomas multiform (GBM) and 22 anaplastic astrocytomas (AA), and 15 patients had low-grade gliomas. Apparent diffusion coefficient (ADC) values of tumor and peritumoral edema, and ADC ratios (ADC in tumor or peritumoral edema to ADC of contralateral white matter, as well as ADC in tumor to ADC in peritumoral edema) were determined from three regions of interest. The average of the mean, maximum, and minimum for ADC variables was calculated for each patient. The metabolite ratios of Cho/Cr and Cho/NAA at intermediate TE were assessed from spectral maps in the solid portion of tumor, peritumoral edema and contralateral normal-appearing white matter. Tumor grade determined with the two methods was then compared with that from histopathologic grading. Logistic regression and receiver operating characteristic (ROC) curve analysis were performed to determine optimum thresholds for tumor grading. Measures of diagnostic examination performance, such as sensitivity, specificity, PPV, NPV, AUC, and accuracy for identifying high-grade gliomas were also calculated

  9. Solar pulsations

    Zirker, J.B.

    1980-01-01

    Oscillations of the surface of the sun, with periods between 5 and 160 min, have been observed by several spectroscopic techniques, and preliminary interpretations have been offered. The 5-min oscillations are global, nonradial, acoustic standing waves in the subsurface zone. Internal differential rotation speeds have been deduced from the Doppler splitting of these waves. Oscillations with longer periods have been reported, but need confirmation. The longest periods offer a tool for investigating the solar interior

  10. Development of a Lyman-α Imaging Solar Telescope for the Satellite

    M. Jang

    2005-09-01

    Full Text Available Long term observations of full-disk Lyman-α irradiance have been made by the instruments on various satellites. In addition, several sounding rockets dating back to the 1950s and up through the present have measured the Lyman-α irradiance. Previous full disk Lyman-α images of the sun have been very interesting and useful scientifically, but have been only five-minute ``snapshots" obtained on sounding rocket flights. All of these observations to date have been snapshots, with no time resolution to observe changes in the chromospheric structure as a result of the evolving magnetic field, and its effect on the Lyman-α intensity. The Lyman-α Imaging Solar Telescope(LIST can provide a unique opportunity for the study of the sun in the Lyman-α region with the high time and spatial resolution for the first time. Up to the 2nd year development, the preliminary design of the optics, mechanical structure and electronics system has been completed. Also the mechanical structure analysis, thermal analysis were performed and the material for the structure was chosen as a result of these analyses. And the test plan and the verification matrix were decided. The operation systems, technical and scientific operation, were studied and finally decided. Those are the technical operation, mechanical working modes for the observation and safety, the scientific operation and the process of the acquired data. The basic techniques acquired through the development of satellite based solar telescope are essential for the construction of space environment forecast system in the future. The techniques which we developed through this study, like mechanical, optical and data processing techniques, could be applied extensively not only to the process of the future production of flight models of this kind, but also to the related industries. Also, we can utilize the scientific achievements which are obtained throughout the project. And these can be utilized to build a high

  11. Prospective Out-of-ecliptic White-light Imaging of Interplanetary Corotating Interaction Regions at Solar Maximum

    Xiong, Ming; Yang, Liping; Liu, Ying D.; Keiji, Hayashi; Li, Huichao [State Key Laboratory of Space Weather, National Space Science Center, Chinese Academy of Sciences, Beijing (China); Davies, Jackie A.; Harrison, Richard A. [RAL Space, STFC-Rutherford Appleton Laboratory, Harwell Campus, Didcot (United Kingdom); Li, Bo; Xia, Lidong, E-mail: mxiong@spacweather.ac.cn [Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment, Institute of Space Sciences, Shandong University, Weihai (China)

    2017-07-20

    Interplanetary corotating interaction regions (CIRs) can be remotely imaged in white light (WL), as demonstrated by the Solar Mass Ejection Imager (SMEI) on board the Coriolis spacecraft and Heliospheric Imagers (HIs) on board the twin Solar TErrestrial RElations Observatory ( STEREO ) spacecraft. The interplanetary WL intensity, due to Thomson scattering of incident sunlight by free electrons, is jointly determined by the 3D distribution of electron number density and line-of-sight (LOS) weighting factors of the Thomson-scattering geometry. The 2D radiance patterns of CIRs in WL sky maps look very different from different 3D viewpoints. Because of the in-ecliptic locations of both the STEREO and Coriolis spacecraft, the longitudinal dimension of interplanetary CIRs has, up to now, always been integrated in WL imagery. To synthesize the WL radiance patterns of CIRs from an out-of-ecliptic (OOE) vantage point, we perform forward magnetohydrodynamic modeling of the 3D inner heliosphere during Carrington Rotation CR1967 at solar maximum. The mixing effects associated with viewing 3D CIRs are significantly minimized from an OOE viewpoint. Our forward modeling results demonstrate that OOE WL imaging from a latitude greater than 60° can (1) enable the garden-hose spiral morphology of CIRs to be readily resolved, (2) enable multiple coexisting CIRs to be differentiated, and (3) enable the continuous tracing of any interplanetary CIR back toward its coronal source. In particular, an OOE view in WL can reveal where nascent CIRs are formed in the extended corona and how these CIRs develop in interplanetary space. Therefore, a panoramic view from a suite of wide-field WL imagers in a solar polar orbit would be invaluable in unambiguously resolving the large-scale longitudinal structure of CIRs in the 3D inner heliosphere.

  12. Gemini Spectroscopic Survey of Young Intermediate-Mass Star-Forming Regions

    Lundquist, Michael; Kobulnicky, Henry

    2018-01-01

    The majority of stars form in embedded clusters. Current research into star formation has focused on either high-mass star-forming regions or low-mass star-forming regions. We present the results from a Gemini spectroscopic survey of young intermediate-mass star-forming regions. These are star forming regions selected to produce stars up to but not exceeding 8 solar masses. We obtained spectra of these regions with GNIRS on Gemini North and Flamingos-2 on Gemini South. We also combine this with near-infrared imaging from 2MASS, UKIDSS, and VVV to study the stellar content.

  13. Spectroscopic Characterization of GEO Satellites with Gunma LOW Resolution Spectrograph

    Endo, T.; Ono, H.; Hosokawa, M.; Ando, T.; Takanezawa, T.; Hashimoto, O.

    The spectroscopic observation is potentially a powerful tool for understanding the Geostationary Earth Orbit (GEO) objects. We present here the results of an investigation of energy spectra of GEO satellites obtained from a groundbased optical telescope. The spectroscopic observations were made from April to June 2016 with the Gunma LOW resolution Spectrograph and imager (GLOWS) at the Gunma Astronomical Observatory (GAO) in JAPAN. The observation targets consist of eleven different satellites: two weather satellites, four communications satellites, and five broadcasting satellites. All the spectra of those GEO satellites are inferred to be solar-like. A number of well-known absorption features such as H-alpha, H-beta, Na-D,water vapor and oxygen molecules are clearly seen in thewavelength range of 4,000 - 8,000 Å. For comparison, we calculated the intensity ratio of the spectra of GEO satellites to that of the Moon which is the natural satellite of the earth. As a result, the following characteristics were obtained. 1) Some variations are seen in the strength of absorption features of water vapor and oxygen originated by the telluric atmosphere, but any other characteristic absorption features were not found. 2) For all observed satellites, the intensity ratio of the spectrum of GEO satellites decrease as a function of wavelength or to be flat. It means that the spectral reflectance of satellite materials is bluer than that of the Moon. 3) A characteristic dip at around 4,800 Å is found in all observed spectra of a weather satellite. Based on these observations, it is indicated that the characteristics of the spectrum are mainly derived from the solar panels because the apparent area of the solar cell is probably larger than that of the satellite body.

  14. Near Real-Time Photometric Data Processing for the Solar Mass Ejection Imager (SMEI)

    Hick, P. P.; Buffington, A.; Jackson, B. V.

    2004-12-01

    The Solar Mass Ejection Imager (SMEI) records a photometric white-light response of the interplanetary medium from Earth over most of the sky in near real time. In the first two years of operation the instrument has recorded the inner heliospheric response to several hundred CMEs, including the May 28, 2003 and the October 28, 2003 halo CMEs. In this preliminary work we present the techniques required to process the SMEI data from the time the raw CCD images become available to their final assembly in photometrically accurate maps of the sky brightness relative to a long-term time base. Processing of the SMEI data includes integration of new data into the SMEI data base; a conditioning program that removes from the raw CCD images an electronic offset ("pedestal") and a temperature-dependent dark current pattern; an "indexing" program that places these CCD images onto a high-resolution sidereal grid using known spacecraft pointing information. At this "indexing" stage further conditioning removes the bulk of the the effects of high-energy-particle hits ("cosmic rays"), space debris inside the field of view, and pixels with a sudden state change ("flipper pixels"). Once the high-resolution grid is produced, it is reformatted to a lower-resolution set of sidereal maps of sky brightness. From these sidereal maps we remove bright stars, background stars, and a zodiacal cloud model (their brightnesses are retained as additional data products). The final maps can be represented in any convenient sky coordinate system. Common formats are Sun-centered Hammer-Aitoff or "fisheye" maps. Time series at selected locations on these maps are extracted and processed further to remove aurorae, variable stars and other unwanted signals. These time series (with a long-term base removed) are used in 3D tomographic reconstructions. The data processing is distributed over multiple PCs running Linux, and, runs as much as possible automatically using recurring batch jobs ('cronjobs'). The

  15. Flare Ribbons Approach Observed by the Interface Region Imaging Spectrograph and the Solar Dynamics Observatory

    Li, Ting; Zhang, Jun; Hou, Yijun, E-mail: liting@nao.cas.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2017-10-10

    We report flare ribbons approach (FRA) during a multiple-ribbon M-class flare on 2015 November 4 in NOAA AR 12443, obtained by the Interface Region Imaging Spectrograph and the Solar Dynamics Observatory. The flare consisted of a pair of main ribbons and two pairs of secondary ribbons. The two pairs of secondary ribbons were formed later than the appearance of the main ribbons, with respective time delays of 15 and 19 minutes. The negative-polarity main ribbon spread outward faster than the first secondary ribbon with the same polarity in front of it, and thus the FRA was generated. Just before their encounter, the main ribbon was darkening drastically and its intensity decreased by about 70% in 2 minutes, implying the suppression of main-phase reconnection that produced two main ribbons. The FRA caused the deflection of the main ribbon to the direction of secondary ribbon with a deflection angle of about 60°. A post-approach arcade was formed about 2 minutes later and the downflows were detected along the new arcade with velocities of 35–40 km s{sup −1}, indicative of the magnetic restructuring during the process of FRA. We suggest that there are three topological domains with footpoints outlined by the three pairs of ribbons. Close proximity of these domains leads to deflection of the ribbons, which is in agreement with the magnetic field topology.

  16. CHROMOSPHERIC AND CORONAL OBSERVATIONS OF SOLAR FLARES WITH THE HELIOSEISMIC AND MAGNETIC IMAGER

    Martínez Oliveros, Juan-Carlos; Krucker, Säm; Hudson, Hugh S.; Saint-Hilaire, Pascal; Bain, Hazel [Space Sciences Laboratory, UC Berkeley, Berkeley, CA 94720 (United States); Lindsey, Charles [North West Research Associates, CORA Division, Boulder, CO 80301 (United States); Bogart, Rick; Couvidat, Sebastien; Scherrer, Phil [W. W. Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94305 (United States); Schou, Jesper [Max-Planck-Institut für Sonnensystemforschung, Justus-von-Liebig-Weg 3, D-37077 Göttingen (Germany)

    2014-01-10

    We report observations of white-light ejecta in the low corona, for two X-class flares on 2013 May 13, using data from the Helioseismic and Magnetic Imager (HMI) of the Solar Dynamics Observatory. At least two distinct kinds of sources appeared (chromospheric and coronal), in the early and later phases of flare development, in addition to the white-light footpoint sources commonly observed in the lower atmosphere. The gradual emissions have a clear identification with the classical loop-prominence system, but are brighter than expected and possibly seen here in the continuum rather than line emission. We find the HMI flux exceeds the radio/X-ray interpolation of the bremsstrahlung produced in the flare soft X-ray sources by at least one order of magnitude. This implies the participation of cooler sources that can produce free-bound continua and possibly line emission detectable by HMI. One of the early sources dynamically resembles {sup c}oronal rain{sup ,} appearing at a maximum apparent height and moving toward the photosphere at an apparent constant projected speed of 134 ± 8 km s{sup –1}. Not much literature exists on the detection of optical continuum sources above the limb of the Sun by non-coronagraphic instruments and these observations have potential implications for our basic understanding of flare development, since visible observations can in principle provide high spatial and temporal resolution.

  17. Glass sample preparation and performance investigations. [solar x-ray imager

    Johnson, R. Barry

    1992-01-01

    This final report details the work performed under this delivery order from April 1991 through April 1992. The currently available capabilities for integrated optical performance modeling at MSFC for large and complex systems such as AXAF were investigated. The Integrated Structural Modeling (ISM) program developed by Boeing for the U.S. Air Force was obtained and installed on two DECstations 5000 at MSFC. The structural, thermal and optical analysis programs available in ISM were evaluated. As part of the optomechanical engineering activities, technical support was provided in the design of support structure, mirror assembly, filter wheel assembly and material selection for the Solar X-ray Imager (SXI) program. As part of the fabrication activities, a large number of zerodur glass samples were prepared in different sizes and shapes for acid etching, coating and polishing experiments to characterize the subsurface damage and stresses produced by the grinding and polishing operations. Various optical components for AXAF video microscope and the x-ray test facility were also fabricated. A number of glass fabrication and test instruments such as a scatter plate interferometer, a gravity feed saw and some phenolic cutting blades were fabricated, integrated and tested.

  18. Characterization of NPP Visible/Infrared Imager Radiometer Suite (VIIRS) Reflective Solar Bands Dual Gain Anomaly

    Lee, Shihyan; McIntire, Jeff; Oudari, Hassan

    2012-01-01

    The Visible/Infrared Imager Radiometer Suite (VIIRS) contains six dual gain bands in the reflective solar spectrum. The dual gain bands are designed to switch gain mode at pre-defined thresholds to achieve high resolution at low radiances while maintaining the required dynamic range for science. During pre-launch testing, an anomaly in the electronic response before transitioning from high to low gain was discovered and characterized. On-orbit, the anomaly was confirmed using MODIS data collected during Simultaneous Nadir Overpasses (SNOs). The analysis of the Earth scene data shows that dual gain anomaly can be determined at the orbital basis. To characterize the dual gain anomaly, the anomaly region and electronic offsets were tracked per week during the first 8 month of VIIRS operation. The temporal analysis shows the anomaly region can drift 20 DN and is impacted by detectors DC Restore. The estimated anomaly flagging regions cover 2.5 % of the high gain dynamic range and are consistent with prelaunch and on-orbit LUT. The prelaunch results had a smaller anomaly range (30-50 DN) and are likely the results of more stable electronics from the shorter data collection time. Finally, this study suggests future calibration efforts to focus on the anomaly's impact on science products and possible correction method to reduce uncertainties.

  19. Spectroscopic Imaging Scanning Tunneling Microscopy Studies of Electronic Structure in the Superconducting and Pseudogap Phases of Cuprate High-Tc Superconductors

    Fujita, Kazuhiro; Schmidt, Andrew R.; Kim, Eun-Ah; Lawler, Michael J.; Lee, Dung Hai; Davis, J. C.; Eisaki, Hiroshi; Uchida, Shin-ichi

    2012-01-01

    One of the key motivations for the development of atomically resolved spectroscopic imaging scanning tunneling microscopy (SI-STM) has been to probe the electronic structure of cuprate high temperature superconductors. In both the d-wave superconducting (dSC) and the pseudogap (PG) phases of underdoped cuprates, two distinct classes of electronic states are observed using SI-STM. The first class consists of the dispersive Bogoliubov quasiparticles of a homogeneous d-wave superconductor. These are detected below a lower energy scale |E|=Δ0 and only upon a momentum space (k-space) arc which terminates near the lines connecting k=±(π/a0,0) to k=±(0,π/a0). Below optimal doping, this ``nodal'' arc shrinks continuously with decreasing hole density. In both the dSC and PG phases, the only broken symmetries detected in the |E|≤Δ0 states are those of a d-wave superconductor. The second class of states occurs at energies near the pseudogap energy scale |E|˜ Δ1 which is associated conventionally with the ``antinodal'' states near k=±(π/a0,0) and k=±(0,π/a0). We find that these states break the expected 90°-rotational (C4) symmetry of electronic structure within CuO2 unit cells, at least down to 180°-rotational (C2) symmetry (nematic) but in a spatially disordered fashion. This intra-unit-cell C4 symmetry breaking coexists at |E|˜Δ1 with incommensurate conductance modulations locally breaking both rotational and translational symmetries (smectic). The characteristic wavevector Q of the latter is determined, empirically, by the k-space points where Bogoliubov quasiparticle interference terminates, and therefore evolves continuously with doping. The properties of these two classes of |E|˜Δ1 states are indistinguishable in the dSC and PG phases. To explain this segregation of k-space into the two regimes distinguished by the symmetries of their electronic states and their energy scales |E|˜Δ1 and |E|≤Δ0, and to understand how this impacts the electronic

  20. 31P MR spectroscopic imaging in preoperative embolization therapy of meningiomas; Phosphor-31-MR-spektroskopische Bildgebung bei praeoperativer Embolisationstherapie von Meningeomen

    Blankenhorn, M. [Psychiatrische Universitaetsklinik, Ulm (Germany). Abteilung III; Bachert, P.; Kaick, G. van [Deutsches Krebsforschungszentrum Heidelberg (Germany). Forschungsschwerpunkt Radiologische Diagnostik; Semmler, W. [Freie Univ. Berlin (Germany). Inst. fuer Diagnostikforschung; Ende, G. [Zentralinstitut fuer Seelische Gesundheit, Mannheim (Germany). NMR-Forschung in der Psychiatrie; Tronnier, V. [Neurochirurgische Klinik, Klinikum der Universitaet, Heidelberg (Germany); Sartor, K. [Neurologische Klinik, Klinikum der Universitaet, Heidelberg (Germany). Abt. Neuroradiologie

    1999-06-01

    Purpose: {sup 31}P MR spectroscopic imaging ({sup 31}P SI) was evaluated in a clinical study as a method for monitoring presurgical devascularization of meningiomas. The aim was to assess noninvasively metabolic alterations in tumor and in healthy brain tissue before and after embolization. Methods: Localized {sup 31}P MR spectra of the brain were obtained by means of 2D-SI (voxel size: 36 cm{sup 3}) using a 1,5-T whole-body MR tomograph. Results: Eleven of 19 patients with intracranial meningiomas examined in this study underwent preoperative embolization therapy; eight patients were examined before and after treatment. After embolization, alterations of pH and of the concentrations of high-energy phosphates (nucleoside-5`triphosphate=NTP, phosphocreatine=PCr), inorganic phosphate (P{sub i}), and membrane constituents were observed in the tumors. A tendency of [P{sub i}] increase and decrease of [NTP], [PCr], and pH predominated, which is explained by ischemic processes after tumor devascularization. Conclusion: {sup 31}P SI is applicable in clinical studies and detects alterations of phosphate metabolism in a meningioma after embolization. (orig.) [Deutsch] Ziel: Die {sup 31}P-MR-spektroskopische Bildgebung ({sup 31}P-SI) wurde im Rahmen der praeoperativen Embolisationstherapie von Patienten mit Meningeomen als Methode zur Therapieverlaufskontrolle klinisch geprueft. Ziel der Studie war die nichtinvasive Erfassung von Veraenderungen im Metabolismus der Tumoren vor und nach Embolisation im Vergleich zum gesunden Hirngewebe. Methoden: Lokalisierte {sup 31}P-MR-Spektren des Gehirns wurden mit 2D-SI (Voxelgroesse: 36 cm{sup 3}) an einem 1,5-T-Ganzkoerper-MR-Tomographen aufgenommen. Ergebnisse: Elf von insgesamt 19 untersuchten Patienten unterzogen sich einer praeoperativen Embolisation, bei acht Patienten konnte eine Verlaufskontrolle durchgefuehrt werden. Nach Embolisation wurden Veraenderungen des pH und der Konzentrationen von energiereichen Phosphaten (Nukleosid

  1. Pilot Assessment of Brain Metabolism in Perinatally HIV-Infected Youths Using Accelerated 5D Echo Planar J-Resolved Spectroscopic Imaging.

    Iqbal, Zohaib; Wilson, Neil E; Keller, Margaret A; Michalik, David E; Church, Joseph A; Nielsen-Saines, Karin; Deville, Jaime; Souza, Raissa; Brecht, Mary-Lynn; Thomas, M Albert

    2016-01-01

    To measure cerebral metabolite levels in perinatally HIV-infected youths and healthy controls using the accelerated five dimensional (5D) echo planar J-resolved spectroscopic imaging (EP-JRESI) sequence, which is capable of obtaining two dimensional (2D) J-resolved spectra from three spatial dimensions (3D). After acquisition and reconstruction of the 5D EP-JRESI data, T1-weighted MRIs were used to classify brain regions of interest for HIV patients and healthy controls: right frontal white (FW), medial frontal gray (FG), right basal ganglia (BG), right occipital white (OW), and medial occipital gray (OG). From these locations, respective J-resolved and TE-averaged spectra were extracted and fit using two different quantitation methods. The J-resolved spectra were fit using prior knowledge fitting (ProFit) while the TE-averaged spectra were fit using the advanced method for accurate robust and efficient spectral fitting (AMARES). Quantitation of the 5D EP-JRESI data using the ProFit algorithm yielded significant metabolic differences in two spatial locations of the perinatally HIV-infected youths compared to controls: elevated NAA/(Cr+Ch) in the FW and elevated Asp/(Cr+Ch) in the BG. Using the TE-averaged data quantified by AMARES, an increase of Glu/(Cr+Ch) was shown in the FW region. A strong negative correlation (r 0.6) were shown between Asp/(Cr+Ch) and CD4 counts in the FG and BG. The complimentary results using ProFit fitting of J-resolved spectra and AMARES fitting of TE-averaged spectra, which are a subset of the 5D EP-JRESI acquisition, demonstrate an abnormal energy metabolism in the brains of perinatally HIV-infected youths. This may be a result of the HIV pathology and long-term combinational anti-retroviral therapy (cART). Further studies of larger perinatally HIV-infected cohorts are necessary to confirm these findings.

  2. Infrared Solar Spectroscopic Measurements of Free Tropospheric CO, C2H6, and HCN above Mauna Loa, Hawaii: Seasonal Variations and Evidence for Enhanced Emissions from the Southeast Asian Tropical Fires of 1997-1998

    Rinsland, C. P.; Goldman, A.; Murcray, F. J.; Stephen, T. M.; Pougatchev, N. S.; Fishman, J.; David, S. J.; Blatherwick, R. D.; Novelli, P. C.; Jones, N. B.

    1999-01-01

    High spectral resolution (0.003 per cm) infrared solar absorption measurements of CO, C2H6, and HCN have been recorded at the Network for the Detection of Stratospheric Change station on Mauna Loa, Hawaii, (19.5N, 155.6W, altitude 3.4 km). The observations were obtained on over 250 days between August 1995 and February 1998. Column measurements are reported for the 3.4-16 km altitude region, which corresponds approximately to the free troposphere above the station. Average CO mixing ratios computed for this layer have been compared with flask sampling CO measurements obtained in situ at the station during the same time period. Both show asymmetrical seasonal cycles superimposed on significant variability. The first 2 years of observations exhibit a broad January-April maximum and a sharper CO minimum during late summer. The C2H6 and CO 3.4-16 km columns were highly correlated throughout the observing period with the C2H6/CO slope intermediate between higher and lower values derived from similar infrared spectroscopic measurements at 32'N and 45'S latitude, respectively. Variable enhancements in CO, C2H6, and particularly HCN were observed beginning in about September 1997. The maximum HCN free tropospheric monthly mean column observed in November 1997 corresponds to an average 3.4-16 km mixing ratio of 0.7 ppbv (1 ppbv = 10(exp -9) per unit volume), more than a factor of 3 above the background level. The HCN enhancements continued through the end of the observational series. Back-trajectory calculations suggest that the emissions originated at low northern latitudes in southeast Asia. Surface CO mixing ratios and the C2H6 tropospheric columns measured during the same time also showed anomalous autumn 1997 maxima. The intense and widespread tropical wild fires that burned during the strong El Nino warm phase of 1997- 1998 are the likely source of the elevated emission products.

  3. Detection of Normal Aging Effects on Human Brain Metabolite Concentrations and Microstructure with Whole-Brain MR Spectroscopic Imaging and Quantitative MR Imaging.

    Eylers, V V; Maudsley, A A; Bronzlik, P; Dellani, P R; Lanfermann, H; Ding, X-Q

    2016-03-01

    Knowledge of age-related physiological changes in the human brain is a prerequisite to identify neurodegenerative diseases. Therefore, in this study whole-brain (1)H-MRS was used in combination with quantitative MR imaging to study the effects of normal aging on healthy human brain metabolites and microstructure. Sixty healthy volunteers, 21-70 years of age, were studied. Brain maps of the metabolites NAA, creatine and phosphocreatine, and Cho and the tissue irreversible and reversible transverse relaxation times T2 and T2' were derived from the datasets. The relative metabolite concentrations and the values of relaxation times were measured with ROIs placed within the frontal and parietal WM, centrum semiovale, splenium of the corpus callosum, hand motor area, occipital GM, putamen, thalamus, pons ventral/dorsal, and cerebellar white matter and posterior lobe. Linear regression analysis and Pearson correlation tests were used to analyze the data. Aging resulted in decreased NAA concentrations in the occipital GM, putamen, splenium of the corpus callosum, and pons ventral and decreased creatine and phosphocreatine concentrations in the pons dorsal and putamen. Cho concentrations did not change significantly in selected brain regions. T2 increased in the cerebellar white matter and decreased in the splenium of the corpus callosum with aging, while the T2' decreased in the occipital GM, hand motor area, and putamen, and increased in the splenium of the corpus callosum. Correlations were found between NAA concentrations and T2' in the occipital GM and putamen and between creatine and phosphocreatine concentrations and T2' in the putamen. The effects of normal aging on brain metabolites and microstructure are region-dependent. Correlations between both processes are evident in the gray matter. The obtained data could be used as references for future studies on patients. © 2016 by American Journal of Neuroradiology.

  4. Concentration of sunlight to solar-surface levels using non-imaging optics

    Gleckman, Philip; O'Gallagher, Joseph; Winston, Roland

    1989-05-01

    An account is given of the design and operational principles of a solar concentrator that employs nonimaging optics to achieve a solar flux equal to 56,000 times that of ambient sunlight, yielding temperatures comparable to, and with further development of the device, exceeding those of the solar surface. In this scheme, a parabolic mirror primary concentrator is followed by a secondary concentrator, designed according to the edge-ray method, which is filled with a transparent oil. The device may be used in materials-processing, waste-disposal, and solar-pumped laser applications.

  5. The cause of spatial structure in solar He I 1083 nm multiplet images

    Leenaarts, Jorrit; Golding, Thomas; Carlsson, Mats; Libbrecht, Tine; Joshi, Jayant

    2016-10-01

    Context. The He I 1083 nm is a powerful diagnostic for inferring properties of the upper solar chromosphere, in particular for the magnetic field. The basic formation of the line in one-dimensional models is well understood, but the influence of the complex three-dimensional structure of the chromosphere and corona has however never been investigated. This structure must play an essential role because images taken in He I 1083 nm show structures with widths down to 100 km. Aims: We aim to understand the effect of the three-dimensional temperature and density structure in the solar atmosphere on the formation of the He I 1083 nm line. Methods: We solved the non-LTE radiative transfer problem assuming statistical equilibrium for a simple nine-level helium atom that nevertheless captures all essential physics. As a model atmosphere we used a snapshot from a 3D radiation-MHD simulation computed with the Bifrost code. Ionising radiation from the corona was self-consistently taken into account. Results: The emergent intensity in the He I 1083 nm is set by the source function and the opacity in the upper chromosphere. The former is dominated by scattering of photospheric radiation and does not vary much with spatial location. The latter is determined by the photonionisation rate in the He I ground state continuum, as well as the electron density in the chromosphere. The spatial variation of the flux of ionising radiation is caused by the spatially-structured emissivity of the ionising photons from material at T ≈ 100 kK in the transition region. The hotter coronal material produces more ionising photons, but the resulting radiation field is smooth and does not lead to small-scale variation of the UV flux. The corrugation of the transition region further increases the spatial variation of the amount of UV radiation in the chromosphere. Finally we find that variations in the chromospheric electron density also cause strong variation in He I 1083 nm opacity. We compare our

  6. A Python-based interface to examine motions in time series of solar images

    Campos-Rozo, J. I.; Vargas Domínguez, S.

    2017-10-01

    Python is considered to be a mature programming language, besides of being widely accepted as an engaging option for scientific analysis in multiple areas, as will be presented in this work for the particular case of solar physics research. SunPy is an open-source library based on Python that has been recently developed to furnish software tools to solar data analysis and visualization. In this work we present a graphical user interface (GUI) based on Python and Qt to effectively compute proper motions for the analysis of time series of solar data. This user-friendly computing interface, that is intended to be incorporated to the Sunpy library, uses a local correlation tracking technique and some extra tools that allows the selection of different parameters to calculate, vizualize and analyze vector velocity fields of solar data, i.e. time series of solar filtergrams and magnetograms.

  7. HIGH SPATIAL RESOLUTION OBSERVATIONS OF LOOPS IN THE SOLAR CORONA

    Brooks, David H.; Ugarte-Urra, Ignacio [College of Science, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States); Warren, Harry P. [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States); Winebarger, Amy R. [NASA Marshall Space Flight Center, ZP 13, Huntsville, AL 35812 (United States)

    2013-08-01

    Understanding how the solar corona is structured is of fundamental importance to determine how the Sun's upper atmosphere is heated to high temperatures. Recent spectroscopic studies have suggested that an instrument with a spatial resolution of 200 km or better is necessary to resolve coronal loops. The High Resolution Coronal Imager (Hi-C) achieved this performance on a rocket flight in 2012 July. We use Hi-C data to measure the Gaussian widths of 91 loops observed in the solar corona and find a distribution that peaks at about 270 km. We also use Atmospheric Imaging Assembly data for a subset of these loops and find temperature distributions that are generally very narrow. These observations provide further evidence that loops in the solar corona are often structured at a scale of several hundred kilometers, well above the spatial scale of many proposed physical mechanisms.

  8. Exquisite Nova Light Curves from the Solar Mass Ejection Imager (SMEI)

    Hounsell, R.; Bode, M. F.; Hick, P. P.; Buffington, A.; Jackson, B. V.; Clover, J. M.; Shafter, A. W.; Darnley, M. J.; Mawson, N. R.; Steele, I. A.; Evans, A.; Eyres, S. P. S.; O'Brien, T. J.

    2010-11-01

    We present light curves of three classical novae (CNe; KT Eridani, V598 Puppis, V1280 Scorpii) and one recurrent nova (RS Ophiuchi) derived from data obtained by the Solar Mass Ejection Imager (SMEI) on board the Coriolis satellite. SMEI provides near complete skymap coverage with precision visible-light photometry at 102 minute cadence. The light curves derived from these skymaps offer unprecedented temporal resolution around, and especially before, maximum light, a phase of the eruption normally not covered by ground-based observations. They allow us to explore fundamental parameters of individual objects including the epoch of the initial explosion, the reality and duration of any pre-maximum halt (found in all three fast novae in our sample), the presence of secondary maxima, speed of decline of the initial light curve, plus precise timing of the onset of dust formation (in V1280 Sco) leading to estimation of the bolometric luminosity, white dwarf mass, and object distance. For KT Eri, Liverpool Telescope SkyCamT data confirm important features of the SMEI light curve and overall our results add weight to the proposed similarities of this object to recurrent rather than to CNe. In RS Oph, comparison with hard X-ray data from the 2006 outburst implies that the onset of the outburst coincides with extensive high-velocity mass loss. It is also noted that two of the four novae we have detected (V598 Pup and KT Eri) were only discovered by ground-based observers weeks or months after maximum light, yet these novae reached peak magnitudes of 3.46 and 5.42, respectively. This emphasizes the fact that many bright novae per year are still overlooked, particularly those of the very fast speed class. Coupled with its ability to observe novae in detail even when relatively close to the Sun in the sky, we estimate that as many as five novae per year may be detectable by SMEI.

  9. On-Orbit Performance of the Helioseismic and Magnetic Imager Instrument onboard the Solar Dynamics Observatory

    Hoeksema, J. T.; Baldner, C. S.; Bush, R. I.; Schou, J.; Scherrer, P. H.

    2018-03-01

    The Helioseismic and Magnetic Imager (HMI) instrument is a major component of NASA's Solar Dynamics Observatory (SDO) spacecraft. Since commencement of full regular science operations on 1 May 2010, HMI has operated with remarkable continuity, e.g. during the more than five years of the SDO prime mission that ended 30 September 2015, HMI collected 98.4% of all possible 45-second velocity maps; minimizing gaps in these full-disk Dopplergrams is crucial for helioseismology. HMI velocity, intensity, and magnetic-field measurements are used in numerous investigations, so understanding the quality of the data is important. This article describes the calibration measurements used to track the performance of the HMI instrument, and it details trends in important instrument parameters during the prime mission. Regular calibration sequences provide information used to improve and update the calibration of HMI data. The set-point temperature of the instrument front window and optical bench is adjusted regularly to maintain instrument focus, and changes in the temperature-control scheme have been made to improve stability in the observable quantities. The exposure time has been changed to compensate for a 20% decrease in instrument throughput. Measurements of the performance of the shutter and tuning mechanisms show that they are aging as expected and continue to perform according to specification. Parameters of the tunable optical-filter elements are regularly adjusted to account for drifts in the central wavelength. Frequent measurements of changing CCD-camera characteristics, such as gain and flat field, are used to calibrate the observations. Infrequent expected events such as eclipses, transits, and spacecraft off-points interrupt regular instrument operations and provide the opportunity to perform additional calibration. Onboard instrument anomalies are rare and seem to occur quite uniformly in time. The instrument continues to perform very well.

  10. Using frequency response functions to manage image degradation from equipment vibration in the Daniel K. Inouye Solar Telescope

    McBride, William R.; McBride, Daniel R.

    2016-08-01

    The Daniel K Inouye Solar Telescope (DKIST) will be the largest solar telescope in the world, providing a significant increase in the resolution of solar data available to the scientific community. Vibration mitigation is critical in long focal-length telescopes such as the Inouye Solar Telescope, especially when adaptive optics are employed to correct for atmospheric seeing. For this reason, a vibration error budget has been implemented. Initially, the FRFs for the various mounting points of ancillary equipment were estimated using the finite element analysis (FEA) of the telescope structures. FEA analysis is well documented and understood; the focus of this paper is on the methods involved in estimating a set of experimental (measured) transfer functions of the as-built telescope structure for the purpose of vibration management. Techniques to measure low-frequency single-input-single-output (SISO) frequency response functions (FRF) between vibration source locations and image motion on the focal plane are described. The measurement equipment includes an instrumented inertial-mass shaker capable of operation down to 4 Hz along with seismic accelerometers. The measurement of vibration at frequencies below 10 Hz with good signal-to-noise ratio (SNR) requires several noise reduction techniques including high-performance windows, noise-averaging, tracking filters, and spectral estimation. These signal-processing techniques are described in detail.

  11. Imaging Plasma Density Structures in the Soft X-Rays Generated by Solar Wind Charge Exchange with Neutrals

    Sibeck, David G.; Allen, R.; Aryan, H.; Bodewits, D.; Brandt, P.; Branduardi-Raymont, G.; Brown, G.; Carter, J. A.; Collado-Vega, Y. M.; Collier, M. R.; Connor, H. K.; Cravens, T. E.; Ezoe, Y.; Fok, M.-C.; Galeazzi, M.; Gutynska, O.; Holmström, M.; Hsieh, S.-Y.; Ishikawa, K.; Koutroumpa, D.; Kuntz, K. D.; Leutenegger, M.; Miyoshi, Y.; Porter, F. S.; Purucker, M. E.; Read, A. M.; Raeder, J.; Robertson, I. P.; Samsonov, A. A.; Sembay, S.; Snowden, S. L.; Thomas, N. E.; von Steiger, R.; Walsh, B. M.; Wing, S.

    2018-06-01

    Both heliophysics and planetary physics seek to understand the complex nature of the solar wind's interaction with solar system obstacles like Earth's magnetosphere, the ionospheres of Venus and Mars, and comets. Studies with this objective are frequently conducted with the help of single or multipoint in situ electromagnetic field and particle observations, guided by the predictions of both local and global numerical simulations, and placed in context by observations from far and extreme ultraviolet (FUV, EUV), hard X-ray, and energetic neutral atom imagers (ENA). Each proposed interaction mechanism (e.g., steady or transient magnetic reconnection, local or global magnetic reconnection, ion pick-up, or the Kelvin-Helmholtz instability) generates diagnostic plasma density structures. The significance of each mechanism to the overall interaction (as measured in terms of atmospheric/ionospheric loss at comets, Venus, and Mars or global magnetospheric/ionospheric convection at Earth) remains to be determined but can be evaluated on the basis of how often the density signatures that it generates are observed as a function of solar wind conditions. This paper reviews efforts to image the diagnostic plasma density structures in the soft (low energy, 0.1-2.0 keV) X-rays produced when high charge state solar wind ions exchange electrons with the exospheric neutrals surrounding solar system obstacles. The introduction notes that theory, local, and global simulations predict the characteristics of plasma boundaries such the bow shock and magnetopause (including location, density gradient, and motion) and regions such as the magnetosheath (including density and width) as a function of location, solar wind conditions, and the particular mechanism operating. In situ measurements confirm the existence of time- and spatial-dependent plasma density structures like the bow shock, magnetosheath, and magnetopause/ionopause at Venus, Mars, comets, and the Earth. However, in situ

  12. Massive Young Stellar Objects in the Galactic Center. 1; Spectroscopic Identification from Spitzer/IRS Observations

    An, Deokkeun; Ramirez, Solange V.; Sellgren, Kris; Arendt, Richard G.; Boogert, A. C. Adwin; Robitaille, Thomas P.; Schultheis, Mathias; Cotera, Angela S.; Smith, Howard A.; Stolovy, Susan R.

    2011-01-01

    We present results from our spectroscopic study, using the Infrared Spectrograph (IRS) onboard the Spitzer Space Telescope, designed to identify massive young stellar objects (YSOs) in the Galactic Center (GC). Our sample of 107 YSO candidates was selected based on IRAC colors from the high spatial resolution, high sensitivity Spitzer/IRAC images in the Central Molecular Zone (CMZ), which spans the central approximately 300 pc region of the Milky Way Galaxy. We obtained IRS spectra over 5 micron to 35 micron using both high- and low-resolution IRS modules. We spectroscopically identify massive YSOs by the presence of a 15.4 micron shoulder on the absorption profile of 15 micron CO2 ice, suggestive of CO2 ice mixed with CH30H ice on grains. This 15.4 micron shoulder is clearly observed in 16 sources and possibly observed in an additional 19 sources. We show that 9 massive YSOs also reveal molecular gas-phase absorption from C02, C2H2, and/or HCN, which traces warm and dense gas in YSOs. Our results provide the first spectroscopic census of the massive YSO population in the GC. We fit YSO models to the observed spectral energy distributions and find YSO masses of 8 - 23 solar Mass, which generally agree with the masses derived from observed radio continuum emission. We find that about 50% of photometrically identified YSOs are confirmed with our spectroscopic study. This implies a preliminary star formation rate of approximately 0.07 solar mass/yr at the GC.

  13. The Focusing Optics X-ray Solar Imager (FOXSI): Update & Second Launch Project

    National Aeronautics and Space Administration — Particle acceleration in solar flares and its contribution to coronal heating are among the main  unsolved problems in heliophysics. Accelerated electrons in a...

  14. Spectroscopic classification of transients

    Stritzinger, M. D.; Fraser, M.; Hummelmose, N. N.

    2017-01-01

    We report the spectroscopic classification of several transients based on observations taken with the Nordic Optical Telescope (NOT) equipped with ALFOSC, over the nights 23-25 August 2017.......We report the spectroscopic classification of several transients based on observations taken with the Nordic Optical Telescope (NOT) equipped with ALFOSC, over the nights 23-25 August 2017....

  15. Four-cell solar tracker

    Berdahl, C. M.

    1981-01-01

    Forty cm Sun tracker, consisting of optical telescope and four solar cells, stays pointed at Sun throughout day for maximum energy collection. Each solar cell generates voltage proportional to part of solar image it receives; voltages drive servomotors that keep image centered. Mirrored portion of cylinder extends acquisition angle of device by reflecting Sun image back onto solar cells.

  16. OUTBURST OF COMET 17P/HOLMES OBSERVED WITH THE SOLAR MASS EJECTION IMAGER

    Li Jing; Jewitt, David; Clover, John M.; Jackson, Bernard V.

    2011-01-01

    We present time-resolved photometric observations of the Jupiter family comet 17P/Holmes during its dramatic 2007 outburst. The observations, from the orbiting Solar Mass Ejection Imager (SMEI), provide the most complete measure of the whole-coma brightness, free from the effects of instrumental saturation and with a time resolution well matched to the rapid brightening of the comet. The light curve is divided into two distinct parts. A rapid rise between the first SMEI observation on UT 2007 October 24 06h 37m (mid-integration) and UT 2007 October 25 is followed by a slow decline until the last SMEI observation on UT 2008 April 6 22h 16m (mid-integration). We find that the rate of change of the brightness is reasonably well described by a Gaussian function having a central time of UT 2007 October 24.54 ± 0.01 and a full width at half-maximum of 0.44 ± 0.02 days. The maximum rate of brightening occurs some 1.2 days after the onset of activity. At the peak, the scattering cross-section grows at 1070 ± 40 km 2 s -1 while the (model-dependent) mass loss rates inferred from the light curve reach a maximum at 3 x 10 5 kg s -1 . The integrated mass in the coma lies in the range (2-90) x 10 10 kg, corresponding to 0.2%-10% of the nucleus mass, while the kinetic energy of the ejecta is (0.7-30) megatonnes TNT. The particulate coma mass could be contained within a shell on the nucleus of thickness 1-60 m. This is also the approximate distance traveled by conducted heat in the century since the previous outburst of 17P/Holmes. This coincidence is consistent with, but does not prove, the idea that the outburst was triggered by the action of conducted heat, possibly through the crystallization of buried amorphous ice.

  17. The Spectrometer/Telescope for Imaging X-rays on Solar Orbiter: Flight design, challenges and trade-offs

    Krucker, S.; Bednarzik, M.; Grimm, O.; Hurford, G.J.; Limousin, O.; Meuris, A.; Orleański, P.; Seweryn, K.; Skup, K.R.

    2016-01-01

    STIX is the X-ray spectral imaging instrument on-board the Solar Orbiter space mission of the European Space Agency, and together with nine other instruments will address questions of the interaction between the Sun and the heliosphere. STIX will study the properties of thermal and accelerated electrons near the Sun through their Bremsstrahlung X-ray emission, addressing in particular the emission from flaring regions on the Sun. The design phase of STIX has been concluded. This paper reports the final flight design of the instrument, focusing on design challenges that were faced recently and how they were addressed.

  18. Investigation of Energy Release in Microflares Observed by the Second Sounding Rocket Flight of the Focusing Optics X-ray Solar Imager (FOXSI-2)

    Vievering, J. T.; Glesener, L.; Panchapakesan, S. A.; Ryan, D.; Krucker, S.; Christe, S.; Buitrago-Casas, J. C.; Inglis, A. R.; Musset, S.

    2017-12-01

    Observations of the Sun in hard x-rays can provide insight into many solar phenomena which are not currently well-understood, including the mechanisms behind particle acceleration in flares. RHESSI is the only solar-dedicated imager currently operating in the hard x-ray regime. Though RHESSI has greatly added to our knowledge of flare particle acceleration, the indirect imaging method of rotating collimating optics is fundamentally limited in sensitivity and dynamic range. By instead using a direct imaging technique, the structure and evolution of even small flares and active regions can be investigated in greater depth. FOXSI (Focusing Optics X-ray Solar Imager), a hard x-ray instrument flown on two sounding rocket campaigns, seeks to achieve these improved capabilities by using focusing optics for solar observations in the 4-20 keV range. During the second of the FOXSI flights, flown on December 11, 2014, two microflares were observed, estimated as GOES class A0.5 and A2.5 (upper limits). Here we present current imaging and spectral analyses of these microflares, exploring the nature of energy release and comparing to observations from other instruments. Additionally, we feature the first analysis of data from the FOXSI-2 CdTe strip detectors, which provide improved efficiency above 10 keV. Through this analysis, we investigate the capabilities of FOXSI in enhancing our knowledge of smaller-scale solar events.

  19. Focal plane instrument for the Solar UV-Vis-IR Telescope aboard SOLAR-C

    Katsukawa, Yukio; Suematsu, Yoshinori; Shimizu, Toshifumi; Ichimoto, Kiyoshi; Takeyama, Norihide

    2011-10-01

    It is presented the conceptual design of a focal plane instrument for the Solar UV-Vis-IR Telescope (SUVIT) aboard the next Japanese solar mission SOLAR-C. A primary purpose of the telescope is to achieve precise as well as high resolution spectroscopic and polarimetric measurements of the solar chromosphere with a big aperture of 1.5 m, which is expected to make a significant progress in understanding basic MHD processes in the solar atmosphere. The focal plane instrument consists of two packages: A filtergraph package is to get not only monochromatic images but also Dopplergrams and magnetograms using a tunable narrow-band filter and interference filters. A spectrograph package is to perform accurate spectro-polarimetric observations for measuring chromospheric magnetic fields, and is employing a Littrow-type spectrograph. The most challenging aspect in the instrument design is wide wavelength coverage from 280 nm to 1.1 μm to observe multiple chromospheric lines, which is to be realized with a lens unit including fluoride glasses. A high-speed camera for correlation tracking of granular motion is also implemented in one of the packages for an image stabilization system, which is essential to achieve high spatial resolution and high polarimetric accuracy.

  20. Quantification of Solar Cell Failure Signatures Based on Statistical Analysis of Electroluminescence Images

    Spataru, Sergiu; Parikh, Harsh; Hacke, Peter

    2017-01-01

    We demonstrate a method to quantify the extent of solar cell cracks, shunting, or damaged cell interconnects, present in crystalline silicon photovoltaic (PV) modules by statistical analysis of the electroluminescence (EL) intensity distributions of individual cells within the module. From the EL...... intensity distributions (ELID) of each cell, we calculated summary statistics such as standard deviation, median, skewness and kurtosis, and analyzed how they correlate with the magnitude of the solar cell degradation. We found that the dispersion of the ELID increases with the size and severity...

  1. Quantification of solar cell failure signatures based on statistical analysis of electroluminescence images

    Spataru, Sergiu; Parikh, Harsh; Benatto, Gisele Alves dos Reis

    2017-01-01

    We propose a method to identify and quantify the extent of solar cell cracks, shunting, or damaged cell interconnects, present in crystalline silicon photovoltaic (PV) modules by statistical analysis of the electroluminescence (EL) intensity distributions of individual cells within the module. From...... the EL intensity distributions (ELID) of each cell, we calculated summary statistics such as standard deviation, median, skewness and kurtosis, and analyzed how they correlate with the type of the solar cell degradation. We found that the dispersion of the ELID increases with the size and severity...

  2. Scientific Considerations for Future Spectroscopic Measurements from Space of Activity on the Sun

    Holman, Gordon D.

    2016-01-01

    High-resolution UV and X-ray spectroscopy are important to understanding the origin and evolution of magnetic energy release in the solar atmosphere, as well as the subsequent evolution of heated plasma and accelerated particles. Electromagnetic radiation is observed from plasma heated to temperatures ranging from about 10 k K to above 10 MK, from accelerated electrons emitting photons primarily at X-ray energies, and from ions emitting in gamma rays. These observations require space-based instruments sensitive to emissions at wavelengths shorter than the near UV. This article reviews some recent observations with emphasis on solar eruptive events, the models that describe them, and the measurements they indicate are needed for substantial progress in the future. Specific examples are discussed demonstrating that imaging spectroscopy with a cadence of seconds or better is needed to follow, understand, and predict the evolution of solar activity. Critical to substantial progress is the combination of a judicious choice of UV, EUV, and soft X-ray imaging spectroscopy sensitive to the evolution of this thermal plasma combined with hard X-ray imaging spectroscopy sensitive to suprathermal electrons. The major challenge will be to conceive instruments that, within the bounds of possible technologies and funding, have the flexibility and field of view to obtain spectroscopic observations where and when events occur while providing an optimum balance of dynamic range, spectral resolution and range, and spatial resolution.

  3. Evaluation of saw damage using diamond-coated wire in crystalline silicon solar cells by photoluminescence imaging

    Kinoshita, Kosuke; Kojima, Takuto; Suzuki, Ryota; Kawatsu, Tomoyuki; Nakamura, Kyotaro; Ohshita, Yoshio; Ogura, Atsushi

    2018-05-01

    Si ingots were sliced using a diamond-coated wire, and saw damage was observed even after damage removal etching and texturization. Since invisible microscopic damage was observed only under uncontrolled slice conditions, such damage was identified as saw damage. The wafers with saw damage exhibited the degradation of solar cell conversion efficiency (approximately 1–2% absolute). The results of external quantum efficiency (EQE) measurements showed a slight deterioration of EQE in the short wavelength region. Current–voltage characteristic measurements showed similar results that agreed with the EQE measurement results. In addition, EQE mapping measurements were carried out at various irradiation wavelengths between 350 and 1150 nm. Areas with dark contrasts in EQE mapping correspond to saw damage. In the cells with a low conversion efficiency, both EQE mapping and PL images exhibited dark areas and lines. On the other hand, in the cells with a high conversion efficiency, a uniform distribution of saw damage was observed even with the saw damage in the PL images. We believe that sophisticated control to suppress saw damage during sawing is required to realize higher conversion efficiency solar cells in the future.

  4. Propagating wave in active region-loops, located over the solar disk observed by the Interface Region Imaging Spectrograph

    Zhang, B.; Hou, Y. J.; Zhang, J.

    2018-03-01

    Aims: We aim to ascertain the physical parameters of a propagating wave over the solar disk detected by the Interface Region Imaging Spectrograph (IRIS). Methods: Using imaging data from the IRIS and the Solar Dynamic Observatory (SDO), we tracked bright spots to determine the parameters of a propagating transverse wave in active region (AR) loops triggered by activation of a filament. Deriving the Doppler velocity of Si IV line from spectral observations of IRIS, we have determined the rotating directions of active region loops which are relevant to the wave. Results: On 2015 December 19, a filament was located on the polarity inversion line of the NOAA AR 12470. The filament was activated and then caused a C1.1 two-ribbon flare. Between the flare ribbons, two rotation motions of a set of bright loops were observed to appear in turn with opposite directions. Following the end of the second rotation, a propagating wave and an associated transverse oscillation were detected in these bright loops. In 1400 Å channel, there was bright material flowing along the loops in a wave-like manner, with a period of 128 s and a mean amplitude of 880 km. For the transverse oscillation, we tracked a given loop and determine the transverse positions of the tracking loop in a limited longitudinal range. In both of 1400 Å and 171 Å channels, approximately four periods are distinguished during the transverse oscillation. The mean period of the oscillation is estimated as 143 s and the displacement amplitude as between 1370 km and 690 km. We interpret these oscillations as a propagating kink wave and obtain its speed of 1400 km s-1. Conclusions: Our observations reveal that a flare associated with filament activation could trigger a kink propagating wave in active region loops over the solar disk. Movies associated to Figs. 1-4 are available at http://https://www.aanda.org

  5. Characterization of extra-solar planets with direct-imaging techniques

    Tinetti, G.; Cash, W.; Glassman, T.; Keller, C.U.; Oakley, P.; Snik, F.; Stam, D.; Turnbull, M.

    2009-01-01

    In order to characterize the physical properties of an extra-solar planet one needs to detect planetary radiation, either visible (VIS) to near-infrared (NIR) reflected starlight or infrared (IR) thermal radiation. Both the reflected and thermal flux depend on the size of the planet, the distance

  6. Force Limited Vibration Test of HESSI Imager

    Amato, Deborah; Pankow, David; Thomsen, Knud

    2000-01-01

    The High Energy Solar Spectroscopic Imager (HESSI) is a solar x-ray and gamma-ray observatory scheduled for launch in November 2000. Vibration testing of the HESSI imager flight unit was performed in August 1999. The HESSI imager consists of a composite metering tube, two aluminum trays mounted to the tube on titanium flexure mounts, and nine modulation grids mounted on each tray. The vibration tests were acceleration controlled and force limited, in order to prevent overtesting. The force limited strategy reduced the shaker force and notched the acceleration at resonances. The test set-up, test levels, and results are presented. The development of the force limits is also discussed. The imager successfully survived the vibration testing.

  7. Solar rotation measurements at Mount Wilson. Pt. 2

    Labonte, B.J.; Howard, R.; Carnegie Institution of Washington, Pasadena

    1981-01-01

    Possible sources of systematic error in solar Doppler rotational velocities are examined. Scattered light is shown to affect the Mount Wilson solar rotation results, but this effect is not enough to bring the spectroscopic results in coincidence with the sunspot rotation. Interference fringes at the spectrograph focus at Mount Wilson have in two intervals affected the rotation results. It has been possible to correlate this error with temperature and thus correct for it. A misalignment between the entrance and exit slits is a possible source of error, but for the Mount Wilson slit configuration the amplitude of this effect is negligibly small. Rapid scanning of the solar image also produces no measurable effect. (orig.)

  8. Calibration of Solar Radio Spectrometer of the Purple Mountain Observatory

    Lei, LU; Si-ming, LIU; Qi-wu, SONG; Zong-jun, NING

    2015-10-01

    Calibration is a basic and important job in solar radio spectral observations. It not only deduces the solar radio flux as an important physical quantity for solar observations, but also deducts the flat field of the radio spectrometer to display the radio spectrogram clearly. In this paper, we first introduce the basic method of calibration based on the data of the solar radio spectrometer of Purple Mountain Observatory. We then analyze the variation of the calibration coefficients, and give the calibrated results for a few flares. These results are compared with those of the Nobeyama solar radio polarimeter and the hard X-ray observations of the RHESSI (Reuven Ramaty High Energy Solar Spectroscopic Imager) satellite, it is shown that these results are consistent with the characteristics of typical solar flare light curves. In particular, the analysis on the correlation between the variation of radio flux and the variation of hard X-ray flux in the pulsing phase of a flare indicates that these observations can be used to study the relevant radiation mechanism, as well as the related energy release and particle acceleration processes.

  9. The oldest magnetic record in our solar system identified using nanometric imaging and numerical modeling.

    Shah, Jay; Williams, Wyn; Almeida, Trevor P; Nagy, Lesleis; Muxworthy, Adrian R; Kovács, András; Valdez-Grijalva, Miguel A; Fabian, Karl; Russell, Sara S; Genge, Matthew J; Dunin-Borkowski, Rafal E

    2018-03-21

    Recordings of magnetic fields, thought to be crucial to our solar system's rapid accretion, are potentially retained in unaltered nanometric low-Ni kamacite (~ metallic Fe) grains encased within dusty olivine crystals, found in the chondrules of unequilibrated chondrites. However, most of these kamacite grains are magnetically non-uniform, so their ability to retain four-billion-year-old magnetic recordings cannot be estimated by previous theories, which assume only uniform magnetization. Here, we demonstrate that non-uniformly magnetized nanometric kamacite grains are stable over solar system timescales and likely the primary carrier of remanence in dusty olivine. By performing in-situ temperature-dependent nanometric magnetic measurements using off-axis electron holography, we demonstrate the thermal stability of multi-vortex kamacite grains from the chondritic Bishunpur meteorite. Combined with numerical micromagnetic modeling, we determine the stability of the magnetization of these grains. Our study shows that dusty olivine kamacite grains are capable of retaining magnetic recordings from the accreting solar system.

  10. Common SphinX and RHESSI observations of solar flares

    Mrozek, T.; Gburek, S.; Siarkowski, M.; Sylwester, B.; Sylwester, J.; Gryciuk, M.

    The Polish X-ray spectrofotometer SphinX has observed a great number of solar flares in the year 2009 - during the most quiet solar minimum almost over the last 100 years. Hundreds of flares have been recorded due to excellent sensitivity of SphinX's detectors. The Si-PIN diodes are about 100 times more sensitive to X-rays than GOES X-ray Monitors. SphinX detectors were absolutely calibrated on Earth with a use of the BESSY synchrotron. In space observations were made in the range 1.2-15~keV with 480~eV energy resolution. SphinX data overlap with the low-energy end of the Ramaty High Energy Solar Spectroscopic Imager (RHESSI) data. RHESSI detectors are quite old (7 years in 2009), but still sensitive enough to provide us with observations of extremely weak solar flares such as those which occurred in 2009. We have selected a group of flares simultaneously observed by RHESSI and SphinX and performed a spectroscopic analysis of the data. Moreover, we compared the physical parameters of these flares plasma. Preliminary results of the comparison show very good agreement between both instruments.

  11. Solar Energy Potential Assessment on Rooftops and Facades in Large Built Environments Based on LiDAR Data, Image Processing, and Cloud Computing. Methodological Background, Application, and Validation in Geneva (Solar Cadaster

    Gilles Desthieux

    2018-03-01

    Full Text Available The paper presents the core methodology for assessing solar radiation and energy production on building rooftops and vertical facades (still rarely considered of the inner-city. This integrated tool is based on the use of LiDAR, 2D and 3D cadastral data. Together with solar radiation and astronomical models, it calculates the global irradiance for a set of points located on roofs, ground, and facades. Although the tool takes simultaneously roofs, ground, and facades, different methods of shadow casting are applied. Shadow casting on rooftops is based on image processing techniques. On the other hand, the assessment on facade involves first to create and interpolate points along the facades and then to implement a point-by-point shadow casting routine. The paper is structured in five parts: (i state of the art on the use of 3D GIS and automated processes in assessing solar radiation in the built environment, (ii overview on the methodological framework used in the paper, (iii detailed presentation of the method proposed for solar modeling and shadow casting, in particular by introducing an innovative approach for modeling the sky view factor (SVF, (iv demonstration of the solar model introduced in this paper through applications in Geneva’s building roofs (solar cadaster and facades, (v validation of the solar model in some Geneva’s spots, focusing especially on two distinct comparisons: solar model versus fisheye catchments on partially inclined surfaces (roof component; solar model versus photovoltaic simulation tool PVSyst on vertical surfaces (facades. Concerning the roof component, validation results emphasize global sensitivity related to the density of light sources on the sky vault to model the SVF. The low dense sky model with 145 light sources gives satisfying results, especially when processing solar cadasters in large urban areas, thus allowing to save computation time. In the case of building facades, introducing weighting factor

  12. Particle acceleration in solar flares: observations versus numerical simulations

    Benz, A O; Grigis, P C; Battaglia, M

    2006-01-01

    Solar flares are generally agreed to be impulsive releases of magnetic energy. Reconnection in dilute plasma is the suggested trigger for the coronal phenomenon. It releases up to 10 26 J, accelerates up to 10 38 electrons and ions and must involve a volume that greatly exceeds the current sheet dimension. The Ramaty High-Energy Solar Spectroscopic Imager satellite can image a source in the corona that appears to contain the acceleration region and can separate it from other x-ray emissions. The new observations constrain the acceleration process by a quantitative relation between spectral index and flux. We present recent observational results and compare them with theoretical modelling by a stochastic process assuming transit-time damping of fast-mode waves, escape and replenishment. The observations can only be fitted if additional assumptions on trapping by an electric potential and possibly other processes such as isotropization and magnetic trapping are made

  13. Planetcam: A Visible And Near Infrared Lucky-imaging Camera To Study Planetary Atmospheres And Solar System Objects

    Sanchez-Lavega, Agustin; Rojas, J.; Hueso, R.; Perez-Hoyos, S.; de Bilbao, L.; Murga, G.; Ariño, J.; Mendikoa, I.

    2012-10-01

    PlanetCam is a two-channel fast-acquisition and low-noise camera designed for a multispectral study of the atmospheres of the planets (Venus, Mars, Jupiter, Saturn, Uranus and Neptune) and the satellite Titan at high temporal and spatial resolutions simultaneously invisible (0.4-1 μm) and NIR (1-2.5 μm) channels. This is accomplished by means of a dichroic beam splitter that separates both beams directing them into two different detectors. Each detector has filter wheels corresponding to the characteristic absorption bands of each planetary atmosphere. Images are acquired and processed using the “lucky imaging” technique in which several thousand images of the same object are obtained in a short time interval, coregistered and ordered in terms of image quality to reconstruct a high-resolution ideally diffraction limited image of the object. Those images will be also calibrated in terms of intensity and absolute reflectivity. The camera will be tested at the 50.2 cm telescope of the Aula EspaZio Gela (Bilbao) and then commissioned at the 1.05 m at Pic-duMidi Observatory (Franca) and at the 1.23 m telescope at Calar Alto Observatory in Spain. Among the initially planned research targets are: (1) The vertical structure of the clouds and hazes in the planets and their scales of variability; (2) The meteorology, dynamics and global winds and their scales of variability in the planets. PlanetCam is also expected to perform studies of other Solar System and astrophysical objects. Acknowledgments: This work was supported by the Spanish MICIIN project AYA2009-10701 with FEDER funds, by Grupos Gobierno Vasco IT-464-07 and by Universidad País Vasco UPV/EHU through program UFI11/55.

  14. HIGH-RESOLUTION HELIOSEISMIC IMAGING OF SUBSURFACE STRUCTURES AND FLOWS OF A SOLAR ACTIVE REGION OBSERVED BY HINODE

    Zhao Junwei; Kosovichev, Alexander G.; Sekii, Takashi

    2010-01-01

    We analyze a solar active region observed by the Hinode Ca II H line using the time-distance helioseismology technique, and infer wave-speed perturbation structures and flow fields beneath the active region with a high spatial resolution. The general subsurface wave-speed structure is similar to the previous results obtained from Solar and Heliospheric Observatory/Michelson Doppler Imager observations. The general subsurface flow structure is also similar, and the downward flows beneath the sunspot and the mass circulations around the sunspot are clearly resolved. Below the sunspot, some organized divergent flow cells are observed, and these structures may indicate the existence of mesoscale convective motions. Near the light bridge inside the sunspot, hotter plasma is found beneath, and flows divergent from this area are observed. The Hinode data also allow us to investigate potential uncertainties caused by the use of phase-speed filter for short travel distances. Comparing the measurements with and without the phase-speed filtering, we find out that inside the sunspot, mean acoustic travel times are in basic agreement, but the values are underestimated by a factor of 20%-40% inside the sunspot umbra for measurements with the filtering. The initial acoustic tomography results from Hinode show a great potential of using high-resolution observations for probing the internal structure and dynamics of sunspots.

  15. Microwave imaging of a solar limb flare - Comparison of spectra and spatial geometry with hard X-rays

    Schmahl, E. J.; Kundu, M. R.; Dennis, B. R.

    1985-01-01

    A solar limb flare was mapped using the Very Large Array (VLA) together with hard X-ray (HXR) spectral and spatial observations of the Solar Maximum Mission satellite. Microwave flux records from 2.8 to 19.6 GHz were instrumental in determining the burst spectrum, which has a maximum at 10 GHz. The flux spectrum and area of the burst sources were used to determine the number of electrons producing gyrosynchrotron emission, magnetic field strength, and the energy distribution of gyrosynchrotron-emitting electrons. Applying the thick target model to the HXR spectrum, the number of high energy electrons responsible for the X-ray bursts was found to be 10 to the 36th, and the electron energy distribution was approximately E exp -5, significantly different from the parameters derived from the microwave observations. The HXR imaging observations exhibit some similiarities in size and structure o the first two burst sources mapped with the VLA. However, during the initial burst, the HXR source was single and lower in the corona than the double 6 cm source. The observations are explained in terms of a single loop with an isotropic high-energy electron distribution which produced the microwaves, and a larger beamed component which produced the HXR at the feet of the loop.

  16. Observations of Reconnection Flows in a Flare on the Solar Disk

    Wang, Juntao; Simões, P. J. A.; Jeffrey, N. L. S.; Fletcher, L.; Wright, P. J.; Hannah, I. G.

    2017-01-01

    Magnetic reconnection is a well-accepted part of the theory of solar eruptive events, though the evidence is still circumstantial. Intrinsic to the reconnection picture of a solar eruptive event, particularly in the standard model for two-ribbon flares (CSHKP model), are an advective flow of magnetized plasma into the reconnection region, expansion of field above the reconnection region as a flux rope erupts, retraction of heated post-reconnection loops, and downflows of cooling plasma along those loops. We report on a unique set of Solar Dynamics Observatory /Atmospheric Imaging Assembly imaging and Hinode /EUV Imaging Spectrometer spectroscopic observations of the disk flare SOL2016-03-23T03:54 in which all four flows are present simultaneously. This includes spectroscopic evidence for a plasma upflow in association with large-scale expanding closed inflow field. The reconnection inflows are symmetric, and consistent with fast reconnection, and the post-reconnection loops show a clear cooling and deceleration as they retract. Observations of coronal reconnection flows are still rare, and most events are observed at the solar limb, obscured by complex foregrounds, making their relationship to the flare ribbons, cusp field, and arcades formed in the lower atmosphere difficult to interpret. The disk location and favorable perspective of this event have removed these ambiguities giving a clear picture of the reconnection dynamics.

  17. Observations of Reconnection Flows in a Flare on the Solar Disk

    Wang, Juntao; Simões, P. J. A.; Jeffrey, N. L. S.; Fletcher, L.; Wright, P. J.; Hannah, I. G., E-mail: j.wang.4@research.gla.ac.uk [SUPA, School of Physics and Astronomy, University of Glasgow, Glasgow G12 8QQ (United Kingdom)

    2017-09-20

    Magnetic reconnection is a well-accepted part of the theory of solar eruptive events, though the evidence is still circumstantial. Intrinsic to the reconnection picture of a solar eruptive event, particularly in the standard model for two-ribbon flares (CSHKP model), are an advective flow of magnetized plasma into the reconnection region, expansion of field above the reconnection region as a flux rope erupts, retraction of heated post-reconnection loops, and downflows of cooling plasma along those loops. We report on a unique set of Solar Dynamics Observatory /Atmospheric Imaging Assembly imaging and Hinode /EUV Imaging Spectrometer spectroscopic observations of the disk flare SOL2016-03-23T03:54 in which all four flows are present simultaneously. This includes spectroscopic evidence for a plasma upflow in association with large-scale expanding closed inflow field. The reconnection inflows are symmetric, and consistent with fast reconnection, and the post-reconnection loops show a clear cooling and deceleration as they retract. Observations of coronal reconnection flows are still rare, and most events are observed at the solar limb, obscured by complex foregrounds, making their relationship to the flare ribbons, cusp field, and arcades formed in the lower atmosphere difficult to interpret. The disk location and favorable perspective of this event have removed these ambiguities giving a clear picture of the reconnection dynamics.

  18. Identifying fecal matter contamination in produce fields using multispectral reflectance imaging under ambient solar illumination

    Everard, Colm D.; Kim, Moon S.; Lee, Hoonsoo; O'Donnell, Colm P.

    2016-05-01

    An imaging device to detect fecal contamination in fresh produce fields could allow the producer avoid harvesting fecal contaminated produce. E.coli O157:H7 outbreaks have been associated with fecal contaminated leafy greens. In this study, in-field spectral profiles of bovine fecal matter, soil, and spinach leaves are compared. A common aperture imager designed with two identical monochromatic cameras, a beam splitter, and optical filters was used to simultaneously capture two-spectral images of leaves contaminated with both fecal matter and soil. The optical filters where 10 nm full width half maximum bandpass filters, one at 690 nm and the second at 710 nm. These were mounted in front of the object lenses. New images were created using the ratio of these two spectral images on a pixel by pixel basis. Image analysis results showed that the fecal matter contamination could be distinguished from soil and leaf on the ratio images. The use of this technology has potential to allow detection of fecal contamination in produce fields which can be a source of foodbourne illnesses. It has the added benefit of mitigating cross-contamination during harvesting and processing.

  19. Solar Tower Experiments for Radiometric Calibration and Validation of Infrared Imaging Assets and Analysis Tools for Entry Aero-Heating Measurements

    Splinter, Scott C.; Daryabeigi, Kamran; Horvath, Thomas J.; Mercer, David C.; Ghanbari, Cheryl M.; Ross, Martin N.; Tietjen, Alan; Schwartz, Richard J.

    2008-01-01

    The NASA Engineering and Safety Center sponsored Hypersonic Thermodynamic Infrared Measurements assessment team has a task to perform radiometric calibration and validation of land-based and airborne infrared imaging assets and tools for remote thermographic imaging. The IR assets and tools will be used for thermographic imaging of the Space Shuttle Orbiter during entry aero-heating to provide flight boundary layer transition thermography data that could be utilized for calibration and validation of empirical and theoretical aero-heating tools. A series of tests at the Sandia National Laboratories National Solar Thermal Test Facility were designed for this task where reflected solar radiation from a field of heliostats was used to heat a 4 foot by 4 foot test panel consisting of LI 900 ceramic tiles located on top of the 200 foot tall Solar Tower. The test panel provided an Orbiter-like entry temperature for the purposes of radiometric calibration and validation. The Solar Tower provided an ideal test bed for this series of radiometric calibration and validation tests because it had the potential to rapidly heat the large test panel to spatially uniform and non-uniform elevated temperatures. Also, the unsheltered-open-air environment of the Solar Tower was conducive to obtaining unobstructed radiometric data by land-based and airborne IR imaging assets. Various thermocouples installed on the test panel and an infrared imager located in close proximity to the test panel were used to obtain surface temperature measurements for evaluation and calibration of the radiometric data from the infrared imaging assets. The overall test environment, test article, test approach, and typical test results are discussed.

  20. Bronze age cosmology and rock art images. Solar ships, deer and charts

    Dimitriadis, G.

    Bronze Age societies were technologically complex. The impressive production of metal artefacts embodies clearly their astronomical culture and cosmological viewpoint. Same ascertainment is valid also for rock art. In fact, around the European landscape were discovered several cliffs engraved with solar ships, deer and charts. How one could be interpret them? Which is the hidden mentality? From the end of 3rd millennium-early 2nd millennium B. C. deep technological transformations are made by metals. New inventions such metal extraction for weapon production, horse pulling chariot used for war and the bull pulling one used for trade may shorten the culture and material distances between Central Europe and South Mediterranean area. Indeed, taphonomic studies indicate a specific modification of the human body mortuary traditional disposition (orientated to significant astronomical targets) below a substantial transformation of mortuary apparatus with spot evidence of weapons (halberds, swords, knifes) and ornaments (double spiral, lunar shape pectorals). The famous Trundhold Solar chart, the 2nd millennium terracotta chart form Dupljaja, the solar boats petroglyph in Bohusland and the horse rider carved on Philippi's cliffs were conceived by the same mentality: communion with the divinity. Culture expressions as communicate manifestation attested in rock art were produced by the same mentality presented in Bronze Age art-crafts such as, 1. Culture epidemiologic patterns dispersion took place through out iconographic motives, and, 2. Animals can play a double face function inside an analogical-mythological system: a. animal-reflex; b. animal-agent. The question is: Could such petroglyphs help us to "read" archaeoastronomical properly in an archaeological site?

  1. Characterization of extra-solar planets with direct-imaging techniques

    Tinetti, G.; Cash, W.; Glassman, T.; Keller, C.U.; Oakley, P.; Snik, F.; Stam, D.; Turnbull, M.

    2009-01-01

    In order to characterize the physical properties of an extra-solar planet one needs to detect planetary radiation, either visible (VIS) to near-infrared (NIR) reflected starlight or infrared (IR) thermal radiation. Both the reflected and thermal flux depend on the size of the planet, the distance between the planet and the star, the distance between the observer and the planet, and the planet’s phase angle (i.e. the angle between the star and the observer as seen from the planet). Moreover, t...

  2. Enabling Flexible Polymer Tandem Solar Cells by 3D Ptychographic Imaging

    Dam, Henrik Friis; Andersen, Thomas Rieks; Pedersen, Emil Bøje Lind

    2015-01-01

    one after the other by wet processing leaves plenty of room for error and the process development calls for an analytical technique that enables 3D reconstruction of the layer stack with the possibility to probe thickness, density, and chemistry of the individual layers in the stack. The use......The realization of a complete tandem polymer solar cell under ambient conditions using only printing and coating methods on a flexible substrate results in a fully scalable process but also requires accurate control during layer formation to succeed. The serial process where the layers are added...

  3. Characterization of Organic Solar Cell Devices and their Interfaces under Degradation: Imaging, Electrical and Mechanical Methods

    Corazza, Michael

    Renewable energies are a critical and necessary technological development deeply connected to human evolution and even survival. The extraordinary technological development of the past century brought tremendous changes to the planet which, despite the scepticism of some, are indubitably affecting...... the natural ecosystem and maybe even the destiny of Earth. Human evolution does not mean only advanced technological development, but also deeper consciousness and responsibility for the next generations to come. Everything on Earth exists because of the Sun: heat, wind, life... everything. Therefore, solar...

  4. Solar engine system

    Tan, K.K.; Bahrom Sanugi; Chen, L.C.; Chong, K.K.; Jasmy Yunus; Kannan, K.S.; Lim, B.H.; Noriah Bidin; Omar Aliman; Sahar Salehan; Sheikh Ab Rezan Sheikh A H; Tam, C.M.; Chen, Y.T.

    2001-01-01

    This paper reports the revolutionary solar engine system in Universiti Teknologi Malaysia (UTM). The solar engine is a single cylinder stirling engine driven by solar thermal energy. A first prototype solar engine has been built and demonstrated. A new-concept non-imaging focusing heliostat and a recently invented optical receiver are used in the demonstration. Second generation of prototype solar engine is described briefly. In this paper, the solar engine system development is reported. Measurement for the first prototype engine speed, temperature and specifications are presented. The benefits and potential applications for the future solar engine system, especially for the electricity generating aspect are discussed. (Author)

  5. Thin Silicon Detector Technology for Use in Imaging Solar ENAs Project

    National Aeronautics and Space Administration — Top Level Objective: To enable capabilities for imaging and spectral measurements of energetic neutral hydrogen atoms (ENAs) produced with energies ∼1MeV/nuc in...

  6. High Spectral Resolution, High Cadence, Imaging X-ray Microcalorimeters for Solar Physics - Phase 2 Project

    National Aeronautics and Space Administration — Microcalorimeter x-ray instruments are non-dispersive, high spectral resolution, broad-band, high cadence imaging spectrometers. We have been developing these...

  7. US Participation in the Solar Orbiter Multi Element Telescope for Imaging and Spectroscopy (METIS) Project

    National Aeronautics and Space Administration — The Multi Element Telescope for Imaging and Spectroscopy, METIS, investigation has been conceived to perform off-limb and near-Sun coronagraphy and is motivated by...

  8. Low-Cost Small Satellite Atmospheric Rotating Solar Occultation Imager (ROI)

    National Aeronautics and Space Administration — Utilizing a unique, new occultation technique involving imaging, the ROI concept will meet or exceed the quality of SAGE measurements at a small fraction of the...

  9. Non-parametric PSF estimation from celestial transit solar images using blind deconvolution

    González Adriana

    2016-01-01

    Full Text Available Context: Characterization of instrumental effects in astronomical imaging is important in order to extract accurate physical information from the observations. The measured image in a real optical instrument is usually represented by the convolution of an ideal image with a Point Spread Function (PSF. Additionally, the image acquisition process is also contaminated by other sources of noise (read-out, photon-counting. The problem of estimating both the PSF and a denoised image is called blind deconvolution and is ill-posed. Aims: We propose a blind deconvolution scheme that relies on image regularization. Contrarily to most methods presented in the literature, our method does not assume a parametric model of the PSF and can thus be applied to any telescope. Methods: Our scheme uses a wavelet analysis prior model on the image and weak assumptions on the PSF. We use observations from a celestial transit, where the occulting body can be assumed to be a black disk. These constraints allow us to retain meaningful solutions for the filter and the image, eliminating trivial, translated, and interchanged solutions. Under an additive Gaussian noise assumption, they also enforce noise canceling and avoid reconstruction artifacts by promoting the whiteness of the residual between the blurred observations and the cleaned data. Results: Our method is applied to synthetic and experimental data. The PSF is estimated for the SECCHI/EUVI instrument using the 2007 Lunar transit, and for SDO/AIA using the 2012 Venus transit. Results show that the proposed non-parametric blind deconvolution method is able to estimate the core of the PSF with a similar quality to parametric methods proposed in the literature. We also show that, if these parametric estimations are incorporated in the acquisition model, the resulting PSF outperforms both the parametric and non-parametric methods.

  10. Coronal mass ejection kinematics deduced from white light (Solar Mass Ejection Imager) and radio (Wind/WAVES) observations

    Reiner, M. J.; Jackson, B. V.; Webb, D. F.; Mizuno, D. R.; Kaiser, M. L.; Bougeret, J.-L.

    2005-09-01

    White-light and radio observations are combined to deduce the coronal and interplanetary kinematics of a fast coronal mass ejection (CME) that was ejected from the Sun at about 1700 UT on 2 November 2003. The CME, which was associated with an X8.3 solar flare from W56°, was observed by the Mauna Loa and Solar and Heliospheric Observatory (SOHO) Large-Angle Spectrometric Coronograph (LASCO) coronagraphs to 14 R⊙. The measured plane-of-sky speed of the LASCO CME was 2600 km s-1. To deduce the kinematics of this CME, we use the plane-of-sky white light observations from both the Solar Mass Ejection Imager (SMEI) all-sky camera on board the Coriolis spacecraft and the SOHO/LASCO coronagraph, as well as the frequency drift rate of the low-frequency radio data and the results of the radio direction-finding analysis from the WAVES experiment on the Wind spacecraft. In agreement with the in situ observations for this event, we find that both the white light and radio observations indicate that the CME must have decelerated significantly beginning near the Sun and continuing well into the interplanetary medium. More specifically, by requiring self-consistency of all the available remote and in situ data, together with a simple, but not unreasonable, assumption about the general characteristic of the CME deceleration, we were able to deduce the radial speed and distance time profiles for this CME as it propagated from the Sun to 1 AU. The technique presented here, which is applicable to mutual SMEI/WAVES CME events, is expected to provide a more complete description and better quantitative understanding of how CMEs propagate through interplanetary space, as well as how the radio emissions, generated by propagating CME/shocks, relate to the shock and CME. This understanding can potentially lead to more accurate predictions for the onset times of space weather events, such as those that were observed during this unique period of intense solar activity.

  11. Spectroscopic surveys of LAMOST

    Zhao Yongheng

    2015-01-01

    The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST), a new type of reflecting Schmidt telescope, has been designed and produced in China. It marks a breakthrough for large scale spectroscopic survey observation in that both large aperture and wide field of view have been achieved. LAMOST has the highest spectrum acquisition rate, and from October 2011 to June 2014 it has obtained 4.13 million spectra of celestial objects, of which 3.78 million are spectra of stars, with the stellar parameters of 2.20 million stars included. (author)

  12. Differences in the Pattern of Hemodynamic Response to Self-Face and Stranger-Face