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Sample records for snap amplitudes decreased

  1. Decreasing the amplitude deviation of Guassian filter in surface roughness measurements

    Science.gov (United States)

    Liu, Bo; Wang, Yu

    2008-12-01

    A new approach for decreasing the amplitude characteristic deviation of Guassian filter in surface roughness measurements is presented in this paper. According to Central Limit Theorem, many different Guassian approximation filters could be constructed. By using first-order Butterworth filter and moving average filter to approximate Guassian filter, their directions of amplitude deviation are opposite, and their locations of extreme value are close. So the linear combination of them could reduce the amplitude deviation greatly. The maximum amplitude deviation is only about 0.11% through paralleling them. The algorithm of this new method is simple and its efficiency is high.

  2. Arsenite reduces insulin secretion in rat pancreatic β-cells by decreasing the calcium-dependent calpain-10 proteolysis of SNAP-25

    International Nuclear Information System (INIS)

    Diaz-Villasenor, Andrea; Burns, Anna L.; Salazar, Ana Maria; Sordo, Monserrat; Hiriart, Marcia; Cebrian, Mariano E.; Ostrosky-Wegman, Patricia

    2008-01-01

    An increase in the prevalence of type 2 diabetes has been consistently observed among residents of high arsenic exposure areas. We have previously shown that in rat pancreatic β-cells, low arsenite doses impair the secretion of insulin without altering its synthesis. To further study the mechanism by which arsenite reduces insulin secretion, we evaluated the effects of arsenite on the calcium-calpain pathway that triggers insulin exocytosis in RINm5F cells. Cell cycle and proliferation analysis were also performed to complement the characterization. Free [Ca 2+ ]i oscillations needed for glucose-stimulated insulin secretion were abated in the presence of subchronic low arsenite doses (0.5-2 μM). The global activity of calpains increased with 2 μM arsenite. However, during the secretion of insulin stimulated with glucose (15.6 mM), 1 μM arsenite decreased the activity of calpain-10, measured as SNAP-25 proteolysis. Both proteins are needed to fuse insulin granules with the membrane to produce insulin exocytosis. Arsenite also induced a slowdown in the β cell line proliferation in a dose-dependent manner, reflected by a reduction of dividing cells and in their arrest in G2/M. Data obtained showed that one of the mechanisms by which arsenite impairs insulin secretion is by decreasing the oscillations of free [Ca 2+ ]i, thus reducing calcium-dependent calpain-10 partial proteolysis of SNAP-25. The effects in cell division and proliferation observed with arsenite exposure can be an indirect consequence of the decrease in insulin secretion

  3. Digital Snaps

    DEFF Research Database (Denmark)

    Sandbye, Mette; Larsen, Jonas

    . Distance as the New Punctum / Mikko Villi -- pt. II. FAMILY ALBUMS IN TRANSITION -- ch. 4. How Digital Technologies Do Family Snaps, Only Better / Gillian Rose -- ch. 5. Friendship Photography: Memory, Mobility and Social Networking / Joanne Garde-Hansen -- ch. 6. Play, Process and Materiality in Japanese...... -- ch. 9. Retouch Yourself: The Pleasures and Politics of Digital Cosmetic Surgery / Tanya Sheehan -- ch. 10. Virtual Selves: Art and Digital Autobiography / Louise Wolthers -- ch. 11. Mobile-Media Photography: New Modes of Engagement / Michael Shanks and Connie Svabo....

  4. Decrease of Fisher information and the information geometry of evolution equations for quantum mechanical probability amplitudes.

    Science.gov (United States)

    Cafaro, Carlo; Alsing, Paul M

    2018-04-01

    The relevance of the concept of Fisher information is increasing in both statistical physics and quantum computing. From a statistical mechanical standpoint, the application of Fisher information in the kinetic theory of gases is characterized by its decrease along the solutions of the Boltzmann equation for Maxwellian molecules in the two-dimensional case. From a quantum mechanical standpoint, the output state in Grover's quantum search algorithm follows a geodesic path obtained from the Fubini-Study metric on the manifold of Hilbert-space rays. Additionally, Grover's algorithm is specified by constant Fisher information. In this paper, we present an information geometric characterization of the oscillatory or monotonic behavior of statistically parametrized squared probability amplitudes originating from special functional forms of the Fisher information function: constant, exponential decay, and power-law decay. Furthermore, for each case, we compute both the computational speed and the availability loss of the corresponding physical processes by exploiting a convenient Riemannian geometrization of useful thermodynamical concepts. Finally, we briefly comment on the possibility of using the proposed methods of information geometry to help identify a suitable trade-off between speed and thermodynamic efficiency in quantum search algorithms.

  5. Decrease of Fisher information and the information geometry of evolution equations for quantum mechanical probability amplitudes

    Science.gov (United States)

    Cafaro, Carlo; Alsing, Paul M.

    2018-04-01

    The relevance of the concept of Fisher information is increasing in both statistical physics and quantum computing. From a statistical mechanical standpoint, the application of Fisher information in the kinetic theory of gases is characterized by its decrease along the solutions of the Boltzmann equation for Maxwellian molecules in the two-dimensional case. From a quantum mechanical standpoint, the output state in Grover's quantum search algorithm follows a geodesic path obtained from the Fubini-Study metric on the manifold of Hilbert-space rays. Additionally, Grover's algorithm is specified by constant Fisher information. In this paper, we present an information geometric characterization of the oscillatory or monotonic behavior of statistically parametrized squared probability amplitudes originating from special functional forms of the Fisher information function: constant, exponential decay, and power-law decay. Furthermore, for each case, we compute both the computational speed and the availability loss of the corresponding physical processes by exploiting a convenient Riemannian geometrization of useful thermodynamical concepts. Finally, we briefly comment on the possibility of using the proposed methods of information geometry to help identify a suitable trade-off between speed and thermodynamic efficiency in quantum search algorithms.

  6. Elementary chaotic snap flows

    International Nuclear Information System (INIS)

    Munmuangsaen, Buncha; Srisuchinwong, Banlue

    2011-01-01

    Highlights: → Five new elementary chaotic snap flows and a generalization of an existing chaotic snap flow have been presented. → Three of all are conservative systems whilst three others are dissipative systems. → Four cases need only a single control parameter and a single nonlinearity. → A cubic case in a jerk representation requires only two terms and a single nonlinearity. - Abstract: Hyperjerk systems with 4th-order derivative of the form x .... =f(x ... ,x .. ,x . ,x) have been referred to as snap systems. Five new elementary chaotic snap flows and a generalization of an existing flow are presented through an extensive numerical search. Four of these flows demonstrate elegant simplicity of a single control parameter based on a single nonlinearity of a quadratic, a piecewise-linear or an exponential type. Two others demonstrate elegant simplicity of all unity-in-magnitude parameters based on either a single cubic nonlinearity or three cubic nonlinearities. The chaotic snap flow with a single cubic nonlinearity requires only two terms and can be transformed to its equivalent dynamical form of only five terms which have a single nonlinearity. An advantage is that such a chaotic flow offers only five terms even though the (four) dimension is high. Three of the chaotic snap flows are characterized as conservative systems whilst three others are dissipative systems. Basic dynamical properties are described.

  7. SNAP operating system reference manual

    International Nuclear Information System (INIS)

    Sabuda, J.D.; Polito, J.; Walker, J.L.; Grant, F.H. III.

    1982-03-01

    The SNAP Operating System (SOS) is a FORTRAN 77 program which provides assistance to the safeguards analyst who uses the Safeguards Automated Facility Evaluation (SAFE) and the Safeguards Network Analysis Procedure (SNAP) techniques. Features offered by SOS are a data base system for storing a library of SNAP applications, computer graphics representation of SNAP models, a computer graphics editor to develop and modify SNAP models, a SAFE-to-SNAP interface, automatic generation of SNAP input data, and a computer graphic post-processor for SNAP. The SOS Reference Manual provides detailed application information concerning SOS as well as a detailed discussion of all SOS components and their associated command input formats. SOS was developed for the US Nuclear Regulatory Commission's Office of Nuclear Regulatory Research and the US Naval Surface Weapons Center by Pritsker and Associates, Inc., under contract to Sandia National Laboratories

  8. SNAP Telescope Latest Developments

    Science.gov (United States)

    Lampton, M.; SNAP Collaboration

    2004-12-01

    The coming era of precision cosmology imposes new demands on space telescopes with regard to spectrophotometric accuracy and image stability. To meet these requirements for SNAP we have developed an all reflecting two-meter-class space telescope of the three-mirror anastigmat type. Our design features a large flat annular field (1.5 degrees = 580mm diameter) and a telephoto advantage of 6, delivering a 22m focal length within an optical package length of only 3.5 meters. The use of highly stable materials (Corning ULE glass and carbon-fiber reinforced cyanate ester resin for the metering structure) combined with agressive distributed thermal control and an L2 orbit location will lead to unmatched figure stability. Owing to our choice of rigid structure with nondeployable solar panels, finite-element models show no structural resonances below 10Hz. An exhaustive stray light study has been completed. Beginning in 2005, two industry studies will develop plans for fabrication, integration and test, bringing SNAP to a highly realistic level of definition. SNAP is supported by the Office of Science, US DoE, under contract DE-AC03-76SF00098.

  9. Snap-top nanocarriers

    KAUST Repository

    Ambrogio, Michael W.

    2010-08-06

    (Equation Presented). An approach to the design and fabrication of mechanized mesoporous silica nanoparticles is demonstrated at the proof of principle level. It relies on the reductive cleavage of disulfide bonds within an integrated nanosystem, wherein surface-bound rotaxanes incorporate disulfide bonds in their stalks,-which are encircled by cucurbit[6]uril or α-cyclodextrin rings, until reductive chemistry is performed, resulting in the snapping of the stalks of the rotaxanes, leading to cargo release from the inside of the nanoparticles. © 2010 American Chemical Society.

  10. Snap-top nanocarriers

    KAUST Repository

    Ambrogio, Michael W.; Pecorelli, Travis A.; Patel, Kaushik I.; Khashab, Niveen M.; Trabolsi, Ali; Khatib, Hussam A.; Botros, Youssry Y.; Zink, Jeffrey I.; Stoddart, Fraser Fraser Raser

    2010-01-01

    (Equation Presented). An approach to the design and fabrication of mechanized mesoporous silica nanoparticles is demonstrated at the proof of principle level. It relies on the reductive cleavage of disulfide bonds within an integrated nanosystem, wherein surface-bound rotaxanes incorporate disulfide bonds in their stalks,-which are encircled by cucurbit[6]uril or α-cyclodextrin rings, until reductive chemistry is performed, resulting in the snapping of the stalks of the rotaxanes, leading to cargo release from the inside of the nanoparticles. © 2010 American Chemical Society.

  11. Neurokinin B receptor antagonism decreases luteinising hormone pulse frequency and amplitude and delays puberty onset in the female rat.

    Science.gov (United States)

    Li, S Y; Li, X F; Hu, M H; Shao, B; Poston, L; Lightman, S L; O'Byrne, K T

    2014-08-01

    The neural mechanisms controlling puberty onset remain enigmatic. Humans with loss of function mutations in TAC3 or TACR3, the genes encoding neurokinin B (NKB) or its receptor, neurokinin-3 receptor (NK3R), respectively, present with severe congenital gonadotrophin deficiency and pubertal failure. Animal studies have shown ambiguous actions of NKB-NK3R signalling with respect to controlling puberty onset. The present study aimed to determine the role of endogenous NKB-NK3R signalling in the control of pulsatile luteinising hormone (LH) secretion and the timing of puberty onset, and also whether precocious pubertal onset as a result of an obesogenic diet is similarly regulated by this neuropeptide system. Prepubertal female rats, chronically implanted with i.c.v. cannulae, were administered SB222200, a NK3R antagonist, or artificial cerebrospinal fluid via an osmotic mini-pump for 14 days. SB222200 significantly delayed the onset of vaginal opening and first oestrus (as markers of puberty) compared to controls in both normal and high-fat diet fed animals. Additionally, serial blood sampling, via chronic indwelling cardiac catheters, revealed that the increase in LH pulse frequency was delayed and that the LH pulse amplitude was reduced in response to NK3R antagonism, regardless of dietary status. These data suggest that endogenous NKB-NK3R signalling plays a role in controlling the timing of puberty and the associated acceleration of gonadotrophin-releasing hormone pulse generator frequency in the female rat. © 2014 British Society for Neuroendocrinology.

  12. Cardiac Risk and Disordered Eating: Decreased R Wave Amplitude in Women with Bulimia Nervosa and Women with Subclinical Binge/Purge Symptoms.

    Science.gov (United States)

    Green, Melinda; Rogers, Jennifer; Nguyen, Christine; Blasko, Katherine; Martin, Amanda; Hudson, Dominique; Fernandez-Kong, Kristen; Kaza-Amlak, Zauditu; Thimmesch, Brandon; Thorne, Tyler

    2016-11-01

    The purpose of the present study was threefold. First, we examined whether women with bulimia nervosa (n = 12) and women with subthreshold binge/purge symptoms (n = 20) showed decreased mean R wave amplitude, an indicator of cardiac risk, on electrocardiograph compared to asymptomatic women (n = 20). Second, we examined whether this marker was pervasive across experimental paradigms, including before and after sympathetic challenge tasks. Third, we investigated behavioural predictors of this marker, including binge frequency and purge frequency assessed by subtype (dietary restriction, excessive exercise, self-induced vomiting, and laxative abuse). Results of a 3 (ED symptom status) × 5 (experimental condition) mixed factorial ANCOVA (covariates: body mass index, age) indicated women with bulimia nervosa and women with subclinical binge/purge symptoms demonstrated significantly reduced mean R wave amplitude compared to asymptomatic women; this effect was pervasive across experimental conditions. Multiple regression analyses showed binge and purge behaviours, most notably laxative abuse as a purge method, predicted decreased R wave amplitude across all experimental conditions. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

  13. The Classroom Animal: Snapping Turtles.

    Science.gov (United States)

    Kramer, David C.

    1987-01-01

    Describes the distinctive features of the common snapping turtle. Discusses facts and misconceptions held about the turtle. Provides guidelines for proper care and treatment of a young snapper in a classroom environment. (ML)

  14. Ubuntu Core Snaps for Science

    Science.gov (United States)

    Wyngaard, J.

    2017-12-01

    A key challenge in the burgeoning sector of IoT (Internet of Things) is ensuring device and communication security. Ubuntu Core's approach to this is the use of 'snaps'. Along side this growth, scientists are increasingly utilising the many new low cost sensors now available. This work prototypes the use of snaps as a possible avenue to reducing the barrier to entry for scientific use of these low cost sensors while also ensuring proper meta-data is captured. Snaps are contained applications that have been signed. This means that a snap application is unable to read or write to any area of the system beyond its assigned reach, thereby significantly limiting the possible impact of any break in security higher up the stack. Further, application and system updates are automatically verified as authentic before being applied. Additionally, on an embedded system running Ubuntu Core the hardware interface (Gadget), kernel, and OS (Core) are all also snaps and therefore also have acquired these same gains. The result is an architecture that enables: (1) Secure, robust, remote automatic updates of both the OS and applications. (2) A user friendly deployment mechanism.(3) A easy to maintain means of supporting multiple platforms. The above is primarily targeted at non-academic domains, however, it is proposed that the Scientific community can benefit from it too. This work therefore prototypes a snap for sensors on board a small Unmanned Aircraft System (sUAS). For demonstration purposes this snap specifically targets connecting a popular low cost CO2 meter to a Raspberry Pi3 and the popular open source sUAS autopilot Arducopter.

  15. Revised SNAP III Training Manual

    Energy Technology Data Exchange (ETDEWEB)

    Moss, Calvin Elroy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gonzales, Samuel M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Myers, William L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Nelson, Mark Andrew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rothrock, Richard Brian [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Salazar, Samuel A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sorensen, Eric Byron [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sundby, Gary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-21

    The Shielded Neutron Assay Probe (SNAP) technique was developed to determine the leakage neutron source strength of a radioactive object. The original system consisted of an EberlineTM Mini-scaler and discrete neutron detector. The system was operated by obtaining the count rate with the EberlineTM instrument, determining the absolute efficiency from a graph, and calculating the neutron source strength by hand. In 2003 the SNAP III, shown in Figure 1, was designed and built. It required the operator to position the SNAP, and then measure the source-to-detector and detectorto- reflector distances. Next the operator entered the distance measurements and started the data acquisition. The SNAP acquired the required count rate and then calculated and displayed the leakage neutron source strength (NSS). The original design of the SNAP III is described in SNAP III Training Manual (ER-TRN-PLN-0258, Rev. 0, January 2004, prepared by William Baird) This report describes some changes that have been made to the SNAP III. One important change is the addition of a LEMO connector to provide neutron detection output pulses for input to the MC-15. This feature is useful in active interrogation with a neutron generator because the MC-15 has the capability to only record data when it is not gated off by a pulse from the neutron generator. This avoids recording of a lot of data during the generator pulses that are not useful. Another change was the replacement of the infrared RS-232 serial communication output by a similar output via a 4-pin LEMO connector. The current document includes a more complete explanation of how to estimate the amount of moderation around a neutron-emitting source.

  16. SNAP Operating System (SOS) user's guide

    International Nuclear Information System (INIS)

    Sabuda, J.D.; Polito, J.; Walker, J.L.; Grant, F.H. III.

    1982-03-01

    The SNAP Operating System (SOS) is a FORTRAN 77 program which provides assistance to the safeguards analyst who uses the Safeguards Automated Facility Evaluation (SAFE) and the Safeguards Network Analysis Procedure (SNAP) techniques. Features offered by SOS are a data base system for storing a library of SNAP applications, computer graphics representation of SNAP models, a computer graphics editor to develop and modify SNAP models, a SAFE-to-SNAP interface, automatic generation of SNAP input data, and a computer graphics postprocessor for SNAP. The SOS User's Guide is designed to provide the user with the information necessary to use SOS effectively. Examples are used throughout to illustrate the concepts. The format of the user's guide follows the same sequence as would be used in executing an actual application

  17. The Curious Acoustic Behavior of Estuarine Snapping Shrimp: Temporal Patterns of Snapping Shrimp Sound in Sub-Tidal Oyster Reef Habitat.

    Directory of Open Access Journals (Sweden)

    DelWayne R Bohnenstiehl

    Full Text Available Ocean soundscapes convey important sensory information to marine life. Like many mid-to-low latitude coastal areas worldwide, the high-frequency (>1.5 kHz soundscape of oyster reef habitat within the West Bay Marine Reserve (36°N, 76°W is dominated by the impulsive, short-duration signals generated by snapping shrimp. Between June 2011 and July 2012, a single hydrophone deployed within West Bay was programmed to record 60 or 30 seconds of acoustic data every 15 or 30 minutes. Envelope correlation and amplitude information were then used to count shrimp snaps within these recordings. The observed snap rates vary from 1500-2000 snaps per minute during summer to <100 snaps per minute during winter. Sound pressure levels are positively correlated with snap rate (r = 0.71-0.92 and vary seasonally by ~15 decibels in the 1.5-20 kHz range. Snap rates are positively correlated with water temperatures (r = 0.81-0.93, as well as potentially influenced by climate-driven changes in water quality. Light availability modulates snap rate on diurnal time scales, with most days exhibiting a significant preference for either nighttime or daytime snapping, and many showing additional crepuscular increases. During mid-summer, the number of snaps occurring at night is 5-10% more than predicted by a random model; however, this pattern is reversed between August and April, with an excess of up to 25% more snaps recorded during the day in the mid-winter. Diurnal variability in sound pressure levels is largest in the mid-winter, when the overall rate of snapping is at its lowest, and the percentage difference between daytime and nighttime activity is at its highest. This work highlights our lack of knowledge regarding the ecology and acoustic behavior of one of the most dominant soniforous invertebrate species in coastal systems. It also underscores the necessity of long-duration, high-temporal-resolution sampling in efforts to understand the bioacoustics of animal

  18. Snap Down Voltage of a Fast-Scanning Micromirror with Vertical Electrostatic Combdrives

    Science.gov (United States)

    Wada, Hiroyuki; Lee, Daesung; Zappe, Stefan; Krishnamoorthy, Uma; Solgaard, Olav

    2004-02-01

    The parallel transition mode of the snap down of a fast-scanning mirror with vertical combdrives was analyzed. The snap down voltage of such a mirror significantly decreased when offsets between the ideal and actual upper movable comb teeth were more than 0.1 μm. When gap between the upper and lower comb teeth was decreased to increase torque, snap down voltage significantly decreased. The largest offset is induced by the lithography step in the fabrication process of the mirror. Self-alignment is required to increase the resonant frequency of the scanning mirror.

  19. SAFE/SNAP application to shipboard security

    International Nuclear Information System (INIS)

    Grady, L.M.; Walker, J.L.; Polito, J.

    1981-11-01

    An application of the combined Safeguards Automated Facility Evaluation/Safeguards Network Analysis Procedure (SAFE/SNAP) modeling technique to a physical protection system (PPS) aboard a generic ship is described. This application was performed as an example of how the SAFE and SNAP techniques could be used. Estimates of probability of interruption and neutralization for the example shipboard PPS are provided by SAFE as well as an adversary scenario, which serves as input to SNAP. This adversary scenario is analyzed by SNAP through four cases which incorporate increasingly detailed security force tactics. Comparisons between the results of the SAFE and SNAP analyses are made and conclusions drawn on the validity of each technique. Feedback from SNAP to SAFE is described, and recommendations for upgrading the ship based on the results of the SAFE/SNAP application are also discussed

  20. Identification and Characterization of Botulinum Neurotoxin A Substrate Binding Pockets and Their Re-Engineering for Human SNAP-23.

    Science.gov (United States)

    Sikorra, Stefan; Litschko, Christa; Müller, Carina; Thiel, Nadine; Galli, Thierry; Eichner, Timo; Binz, Thomas

    2016-01-29

    Botulinum neurotoxins (BoNTs) are highly potent bacterial proteins that block neurotransmitter release at the neuromuscular junction by cleaving SNAREs (soluble N-ethyl maleimide sensitive factor attachment protein receptors). However, their serotype A (BoNT/A) that cleaves SNAP-25 (synaptosomal-associated protein of 25 kDa) has also been an established pharmaceutical for treatment of medical conditions that rely on hyperactivity of cholinergic nerve terminals for 25 years. The expansion of its use to a variety of further medical conditions associated with hypersecretion components is prevented partly because the involved SNARE isoforms are not cleaved. Therefore, we examined by mutational analyses the reason for the resistance of human SNAP-23, an isoform of SNAP-25. We show that replacement of 10 SNAP-23 residues with their SNAP-25 counterparts effects SNAP-25-like cleavability. Conversely, transfer of each of the replaced SNAP-23 residues to SNAP-25 drastically decreased the cleavability of SNAP-25. By means of the existing SNAP-25-toxin co-crystal structure, molecular dynamics simulations, and corroborative mutagenesis studies, the appropriate binding pockets for these residues in BoNT/A were characterized. Systematic mutagenesis of two major BoNT/A binding pockets was conducted in order to adapt these pockets to corresponding amino acids of human SNAP-23. Human SNAP-23 cleaving mutants were isolated using a newly established yeast-based screening system. This method may be useful for engineering novel BoNT/A pharmaceuticals for the treatment of diseases that rely on SNAP-23-mediated hypersecretion. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. A VESICLE TRAFFICKING PROTEIN αSNAP REGULATES PANETH CELL DIFFERENTIATION IN VIVO

    Science.gov (United States)

    Lechuga, Susana; Naydenov, Nayden G.; Feygin, Alex; Jimenez, Antonio J.; Ivanov, Andrei I.

    2017-01-01

    A soluble N-ethylmaleimide-sensitive factor-attachment protein alpha (αSNAP) is a multifunctional scaffolding protein that regulates intracellular vesicle trafficking and signaling. In cultured intestinal epithelial cells, αSNAP has been shown to be essential for cell survival, motility, and adhesion; however, its physiologic functions in the intestinal mucosa remain unknown. In the present study, we used a mouse with a spontaneous hydrocephalus with hop gait (hyh) mutation of αSNAP to examine the roles of this trafficking protein in regulating intestinal epithelial homeostasis in vivo. Homozygous hyh mice demonstrated decreased expression of αSNAP protein in the intestinal epithelium, but did not display gross abnormalities of epithelial architecture in the colon and ileum. Such αSNAP depletion attenuated differentiation of small intestinal epithelial enteroids ex vivo. Furthermore, αSNAP-deficient mutant animals displayed reduced formation of lysozyme granules in small intestinal crypts and decreased expression of lysozyme and defensins in the intestinal mucosa, which is indicative of defects in Paneth cell differentiation. By contrast, development of Goblet cells, enteroendocrine cells, and assembly of enterocyte apical junctions was not altered in hyh mutant mice. Our data revealed a novel role of αSNAP in the intestinal Paneth cell differentiation in vivo. PMID:28359759

  2. A vesicle trafficking protein αSNAP regulates Paneth cell differentiation in vivo.

    Science.gov (United States)

    Lechuga, Susana; Naydenov, Nayden G; Feygin, Alex; Jimenez, Antonio J; Ivanov, Andrei I

    2017-05-13

    A soluble N-ethylmaleimide-sensitive factor-attachment protein alpha (αSNAP) is a multifunctional scaffolding protein that regulates intracellular vesicle trafficking and signaling. In cultured intestinal epithelial cells, αSNAP has been shown to be essential for cell survival, motility, and adhesion; however, its physiologic functions in the intestinal mucosa remain unknown. In the present study, we used a mouse with a spontaneous hydrocephalus with hop gait (hyh) mutation of αSNAP to examine the roles of this trafficking protein in regulating intestinal epithelial homeostasis in vivo. Homozygous hyh mice demonstrated decreased expression of αSNAP protein in the intestinal epithelium, but did not display gross abnormalities of epithelial architecture in the colon and ileum. Such αSNAP depletion attenuated differentiation of small intestinal epithelial enteroids ex vivo. Furthermore, αSNAP-deficient mutant animals displayed reduced formation of lysozyme granules in small intestinal crypts and decreased expression of lysozyme and defensins in the intestinal mucosa, which is indicative of defects in Paneth cell differentiation. By contrast, development of Goblet cells, enteroendocrine cells, and assembly of enterocyte apical junctions was not altered in hyh mutant mice. Our data revealed a novel role of αSNAP in the intestinal Paneth cell differentiation in vivo. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Safeguards Network Analysis Procedure (SNAP): overview

    International Nuclear Information System (INIS)

    Chapman, L.D; Engi, D.

    1979-08-01

    Nuclear safeguards systems provide physical protection and control of nuclear materials. The Safeguards Network Analysis Procedure (SNAP) provides a convenient and standard analysis methodology for the evaluation of physical protection system effectiveness. This is achieved through a standard set of symbols which characterize the various elements of safeguards systems and an analysis program to execute simulation models built using the SNAP symbology. The outputs provided by the SNAP simulation program supplements the safeguards analyst's evaluative capabilities and supports the evaluation of existing sites as well as alternative design possibilities. This paper describes the SNAP modeling technique and provides an example illustrating its use

  4. Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells

    NARCIS (Netherlands)

    Low, SH; Roche, PA; Anderson, HA; van Ijzendoorn, SCD; Zhang, M; Mostov, KE; Weimbs, T

    1998-01-01

    SNAP-23 is the ubiquitously expressed homologue of the neuronal SNAP-25, which functions in synaptic vesicle fusion, We have investigated the subcellular localization of SNAP-23 in polarized epithelial cells, In hepatocyte-derived HepG2 cells and in Madin-Darby canine kidney (MDCK) cells, the

  5. Valor preditivo dos escores de SNAP e SNAP-PE na mortalidade neonatal Predictive value of SNAP and SNAP-PE for neonatal mortality

    Directory of Open Access Journals (Sweden)

    Rita C. Silveira

    2001-12-01

    Full Text Available OBJETIVOS: avaliar os escores SNAP e SNAP-PE como preditores de mortalidade neonatal na nossa UTI neonatal, comparando seus resultados. MÉTODOS: todos os recém-nascidos admitidos na UTI neonatal no período de março de 1997 a dezembro de 1998 foram avaliados prospectivamente quanto ao SNAP e SNAP-PE com 24 horas de vida. Foram critérios de exclusão o óbito ou alta da UTI nas primeiras 24 horas de vida, as malformações congênitas incompatíveis com a vida, e recém-nascidos transferidos de outros hospitais. RESULTADOS: 553 recém-nascidos foram incluídos, 54 faleceram. Os valores das medianas do SNAP e SNAP-PE foram mais elevados naqueles que não sobreviveram. Os recém-nascidos foram divididos em cinco faixas de gravidade crescente de SNAP e SNAP-PE. SNAP: até 6, 7-11, 12-15, 16-24, acima de 24 (mortalidade: 3%, 11%, 29%, 48%, 75%, respectivamente. SNAP-PE: até 11, 12-23, 24-32, 33-50, acima de 50 (mortalidade: 3%, 10%, 53%, 78%, 83%, respectivamente. A partir da Curva ROC, os pontos de corte foram 12 para SNAP e 24 para SNAP-PE, obtendo-se sensibilidade, especificidade, valor preditivo positivo (VPP e valor preditivo negativo (VPN para mortalidade. SNAP 12: sensibilidade 79,6%, especificidade 71,7%, VPP 23,4%, VPN 97%. SNAP-PE 24: sensibilidade 79,6%, especificidade 80%, VPP 30%, VPN 97,3%. A área abaixo da Curva ROC (Az para SNAP foi 81,4% e para SNAP-PE 85,1%, ambas estatisticamente significativas. A comparação entre as áreas das duas curvas não evidenciou diferença estatisticamente significativa. CONCLUSÕES: os escores SNAP e SNAP-PE são excelentes preditores de sobrevida neonatal, recomendamos sua utilização rotineiramente na admissão de recém-nascidos nas Unidades de Tratamento Intensivo Neonatal.OBJECTIVE: to evaluate the Score for Neonatal Acute Physiology and the Score for Neonatal Acute Physiology Perinatal Extension as neonatal mortality predictors in our neonatal intensive care unit, and to compare their

  6. SNAP Satellite Focal Plane Development

    International Nuclear Information System (INIS)

    Bebek, C.; Akerlof, C.; Aldering, G.; Amanullah, R.; Astier, P.; Baltay, C.; Barrelet, E.; Basa, S.; Bercovitz, J.; Bergstrom, L.; Berstein, G.P.; Bester, M.; Bohlin, R.; Bonissent, A.; Bower, C.; Campbell, M.; Carithers, W.; Commins, E.; Day, C.; Deustua, S.; DiGennaro, R.; Ealet, A.; Ellis, R.; Emmett, W.; Eriksson, M.; Fouchez, D.; Fruchter, A.; Genat, J-F.; Goldhaber, G.; Goobar, A.; Groom, D.; Heetderks, H.; Holland, S.; Huterer, D.; Johnson, W.; Kadel, R.; Karcher, A.; Kim, A.; Kolbe, W.; Lafever, R.; Lamoureaux, J.; Lampton, M.; Lefevre, O.; Levi, M.; Levin, D.; Linder, E.; Loken, S.; Malina, R.; Mazure, A.; McKay, T.; McKee, S.; Miquel, R.; Morgan, N.; Mortsell, E.; Mostek, N.; Mufson, S.; Musser, J.; Roe, N.; Nugent, P.; Oluseyi, H.; Pain, R.; Palaio, N.; Pankow, D.; Perlmutter, S.; Prieto, E.; Rabinowitz, D.; Refregier, A.; Rhodes, J.; Schubnell, M.; Sholl, M.; Smadja, G.; Smith, R.; Smoot, G.; Snyder, J.; Spadafora, A.; Szymkowiak, A.; Tarle, G.; Taylor, K.; Tilquin, A.; Tomasch, A.; Vincent, D.; von der Lippe, H.; Walder, J-P.; Wang, G.

    2003-01-01

    The proposed SuperNova/Acceleration Probe (SNAP) mission will have a two-meter class telescope delivering diffraction-limited images to an instrumented 0.7 square degree field in the visible and near-infrared wavelength regime. The requirements for the instrument suite and the present configuration of the focal plane concept are presented. A two year R and D phase, largely supported by the Department of Energy, is just beginning. We describe the development activities that are taking place to advance our preparedness for mission proposal in the areas of detectors and electronics

  7. Cross-modal attention influences auditory contrast sensitivity: Decreasing visual load improves auditory thresholds for amplitude- and frequency-modulated sounds.

    Science.gov (United States)

    Ciaramitaro, Vivian M; Chow, Hiu Mei; Eglington, Luke G

    2017-03-01

    We used a cross-modal dual task to examine how changing visual-task demands influenced auditory processing, namely auditory thresholds for amplitude- and frequency-modulated sounds. Observers had to attend to two consecutive intervals of sounds and report which interval contained the auditory stimulus that was modulated in amplitude (Experiment 1) or frequency (Experiment 2). During auditory-stimulus presentation, observers simultaneously attended to a rapid sequential visual presentation-two consecutive intervals of streams of visual letters-and had to report which interval contained a particular color (low load, demanding less attentional resources) or, in separate blocks of trials, which interval contained more of a target letter (high load, demanding more attentional resources). We hypothesized that if attention is a shared resource across vision and audition, an easier visual task should free up more attentional resources for auditory processing on an unrelated task, hence improving auditory thresholds. Auditory detection thresholds were lower-that is, auditory sensitivity was improved-for both amplitude- and frequency-modulated sounds when observers engaged in a less demanding (compared to a more demanding) visual task. In accord with previous work, our findings suggest that visual-task demands can influence the processing of auditory information on an unrelated concurrent task, providing support for shared attentional resources. More importantly, our results suggest that attending to information in a different modality, cross-modal attention, can influence basic auditory contrast sensitivity functions, highlighting potential similarities between basic mechanisms for visual and auditory attention.

  8. Dynamics of snapping beams and jumping poppers

    Science.gov (United States)

    Pandey, A.; Moulton, D. E.; Vella, D.; Holmes, D. P.

    2014-01-01

    We consider the dynamic snapping instability of elastic beams and shells. Using the Kirchhoff rod and Föppl-von Kármán plate equations, we study the stability, deformation modes, and snap-through dynamics of an elastic arch with clamped boundaries and subject to a concentrated load. For parameters typical of everyday and technological applications of snapping, we show that the stretchability of the arch plays a critical role in determining not only the post-buckling mode of deformation but also the timescale of snapping and the frequency of the arch's vibrations about its final equilibrium state. We show that the growth rate of the snap-through instability and its subsequent ringing frequency can both be interpreted physically as the result of a sound wave in the material propagating over a distance comparable to the length of the arch. Finally, we extend our analysis of the ringing frequency of indented arches to understand the “pop” heard when everted shell structures snap-through to their stable state. Remarkably, we find that not only are the scaling laws for the ringing frequencies in these two scenarios identical but also the respective prefactors are numerically close; this allows us to develop a master curve for the frequency of ringing in snapping beams and shells.

  9. Snapping plicae associated with radiocapitellar chondromalacia.

    Science.gov (United States)

    Antuna, S A; O'Driscoll, S W

    2001-05-01

    Painful snapping of the elbow joint is usually attributed to intra-articular loose bodies, instability, or medial dislocation of the triceps muscle over the medial epicondyle. We report our experience with 14 patients who were treated arthroscopically for snapping elbow that was found to be caused by hypertrophic synovial folds associated with radiocapitellar chondromalacia. Case series. The records of 14 patients who were treated arthroscopically for painful snapping elbows caused by intra-articular plicae were reviewed. There were 6 women and 8 men with an average age of 36 years (range, 27 to 48 years). Nine patients had had some type of trauma to the joint. Four patients had been previously diagnosed with lateral epicondylitis and 5 with intra-articular loose bodies. The average time from initial onset of symptoms to treatment was 13 months (range, 8 to 36 months). Average follow-up was 24 months (range, 6 to 66 months). All patients complained of painful snapping in the posterolateral or anterolateral aspect of the elbow. The snapping occurred between 90 degrees and 110 degrees of flexion with the forearm in pronation. In 7 patients, the snapping was reproducible by passively flexing the pronated elbow, which we refer to as the flexion-pronation test. At the time of arthroscopic surgery, all patients had a thickened synovial plica that would snap back and forward over the radial head, usually associated with a chondromalacic area on the radial head. Twelve patients had complete relief of their snapping after surgery. One patient in whom there was associated posterolateral rotatory elbow instability did not improve. One patient became asymptomatic for 4 years but then had recurrence of her symptoms, which persisted despite 2 subsequent arthroscopies. The presence of synovial plicae in the radiocapitellar joint must be considered in the differential diagnosis of painful snapping elbow. Arthroscopy confirms the diagnosis and allows excision of the plica.

  10. Snapping Knee Caused by Medial Meniscal Cyst

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Ohishi

    2014-01-01

    Full Text Available Snapping phenomenon around the medial aspect of the knee is rare. We present this case of snapping knee caused by the sartorius muscle over a large medial meniscal cyst in a 66-year-old female. Magnetic resonance images demonstrated a large medial meniscal cyst with a horizontal tear of the medial meniscus. Arthroscopic cyst decompression with limited meniscectomy resulted in the disappearance of snapping, and no recurrence of the cyst was observed during a 2-year follow-up period.

  11. Snap evaporation of droplets on smooth topographies.

    Science.gov (United States)

    Wells, Gary G; Ruiz-Gutiérrez, Élfego; Le Lirzin, Youen; Nourry, Anthony; Orme, Bethany V; Pradas, Marc; Ledesma-Aguilar, Rodrigo

    2018-04-11

    Droplet evaporation on solid surfaces is important in many applications including printing, micro-patterning and cooling. While seemingly simple, the configuration of evaporating droplets on solids is difficult to predict and control. This is because evaporation typically proceeds as a "stick-slip" sequence-a combination of pinning and de-pinning events dominated by static friction or "pinning", caused by microscopic surface roughness. Here we show how smooth, pinning-free, solid surfaces of non-planar topography promote a different process called snap evaporation. During snap evaporation a droplet follows a reproducible sequence of configurations, consisting of a quasi-static phase-change controlled by mass diffusion interrupted by out-of-equilibrium snaps. Snaps are triggered by bifurcations of the equilibrium droplet shape mediated by the underlying non-planar solid. Because the evolution of droplets during snap evaporation is controlled by a smooth topography, and not by surface roughness, our ideas can inspire programmable surfaces that manage liquids in heat- and mass-transfer applications.

  12. Comparative kinematical analyses of Venus flytrap (Dionaea muscipula snap traps

    Directory of Open Access Journals (Sweden)

    Simon Poppinga

    2016-05-01

    Full Text Available Although the Venus flytrap (Dionaea muscipula can be considered as one of the most extensively investigated carnivorous plants, knowledge is still scarce about diversity of the snap-trap motion, the functionality of snap traps under varying environmental conditions, and their opening motion. By conducting simple snap-trap closure experiments in air and under water, we present striking evidence that adult Dionaea snaps similarly fast in aerial and submersed states and, hence, is potentially able to gain nutrients from fast aquatic prey during seasonal inundation. We reveal three snapping modes of adult traps, all incorporating snap buckling, and show that millimeter-sized, much slower seedling traps do not yet incorporate such elastic instabilities. Moreover, opening kinematics of young and adult Dionaea snap traps reveal that reverse snap buckling is not performed, corroborating the assumption that growth takes place on certain trap lobe regions. Our findings are discussed in an evolutionary, biomechanical, functional–morphological and biomimetic context.

  13. SnapShot: The Bacterial Cytoskeleton.

    Science.gov (United States)

    Fink, Gero; Szewczak-Harris, Andrzej; Löwe, Jan

    2016-07-14

    Most bacteria and archaea contain filamentous proteins and filament systems that are collectively known as the bacterial cytoskeleton, though not all of them are cytoskeletal, affect cell shape, or maintain intracellular organization. To view this SnapShot, open or download the PDF. Copyright © 2016. Published by Elsevier Inc.

  14. Method for reducing snap in magnetic amplifiers

    Science.gov (United States)

    Fischer, R. L. E.; Word, J. L.

    1968-01-01

    Method of reducing snap in magnetic amplifiers uses a degenerative feedback circuit consisting of a resistor and a separate winding on a magnetic core. The feedback circuit extends amplifier range by allowing it to be used at lower values of output current.

  15. SNAP and AI Fuel Summary Report

    International Nuclear Information System (INIS)

    Lords, R.E.

    1994-08-01

    The SNAP and AI Fuel Summary Report provides a detailed overview of treatment and storage of these fuels from fabrication through current storage including design parameters and reactor history. Chemical and physical characteristics are described, and potential indicators of as-stored fuel conditions are emphasized

  16. Germination of beans and snap beans seed

    Directory of Open Access Journals (Sweden)

    Zdravković Milan

    2000-01-01

    Full Text Available The aim of this study was to investigate germination of good bean seed of the variety Galeb and the bad bean seed of the same variety. We were also interested in germination of bean and snap bean seed damaged by grain weevil, and in germination of the seed treated by freezing which was aimed at controlling grain weevil by cold. We also recorded the differences between bean and snap bean seed, which was or was not treated by freezing in laboratory conditions. This investigation was carried out by applying the two factorial block system. The obtained results were evaluated by the variance analysis and x2 test These results suggest that the bean seed of a bad fraction had low levels of germination, but still it was present. Although the seed of good appearance was carefully selected, germination was slightly lower than it should have been. The seed with the large amount of grain weevils performed a high level germination in laboratory conditions. There were no differences in germination between the seed injured by grain weevil either in beans or in snap beans. As for the seed treated or untreated by freezing, there also were no differences between beans and snap beans. .

  17. Snap: an integrated SNP annotation platform

    DEFF Research Database (Denmark)

    Li, Shengting; Ma, Lijia; Li, Heng

    2007-01-01

    Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of the platform is to facilitate the study of SNP finding and analysis within the framework of medical...

  18. Jump phenomena. [large amplitude responses of nonlinear systems

    Science.gov (United States)

    Reiss, E. L.

    1980-01-01

    The paper considers jump phenomena composed of large amplitude responses of nonlinear systems caused by small amplitude disturbances. Physical problems where large jumps in the solution amplitude are important features of the response are described, including snap buckling of elastic shells, chemical reactions leading to combustion and explosion, and long-term climatic changes of the earth's atmosphere. A new method of rational functions was then developed which consists of representing the solutions of the jump problems as rational functions of the small disturbance parameter; this method can solve jump problems explicitly.

  19. SNAP - a three dimensional neutron diffusion code

    International Nuclear Information System (INIS)

    McCallien, C.W.J.

    1993-02-01

    This report describes a one- two- three-dimensional multi-group diffusion code, SNAP, which is primarily intended for neutron diffusion calculations but can also carry out gamma calculations if the diffusion approximation is accurate enough. It is suitable for fast and thermal reactor core calculations and for shield calculations. SNAP can solve the multi-group neutron diffusion equations using finite difference methods. The one-dimensional slab, cylindrical and spherical geometries and the two-dimensional case are all treated as simple special cases of three-dimensional geometries. Numerous reflective and periodic symmetry options are available and may be used to reduce the number of mesh points necessary to represent the system. Extrapolation lengths can be specified at internal and external boundaries. (Author)

  20. Scapulothoracic Anatomy and Snapping Scapula Syndrome

    Directory of Open Access Journals (Sweden)

    Rachel M. Frank

    2013-01-01

    Full Text Available The scapulothoracic articulation is a sliding junction between the deep aspect of the scapula and thoracic rib cage at the levels of ribs 2 through 7. Motion at this articulation is dynamically stabilized by a variety of muscular attachments, allowing for controlled positioning of the glenoid to assist in glenohumeral joint function. A thorough understanding of the complex anatomic relationships, including the various muscles, and bursa, is critical to the evaluation of patients presenting with scapulothoracic disorders. The snapping scapula syndrome is caused by either osseous lesions or scapulothoracic bursitis and can be difficult to recognize and treat. The purpose of this review is to discuss the anatomy of the scapulothoracic articulation with an emphasis on the pathology associated with snapping scapula syndrome.

  1. Experimental Snap Loading of Synthetic Ropes

    Directory of Open Access Journals (Sweden)

    C.M. Hennessey

    2005-01-01

    Full Text Available Large tensile forces, known as snap loads, can occur when a slack rope becomes taut. Such forces may damage the rope or masses connected to it. Experiments are described in which one end of a rope is attached to the top of a drop tower and the bottom end is attached to a weight. The weight is raised to a certain height and then released. The force at the top of the rope and the acceleration of the weight are recorded during the first snap load that occurs. Repeated drop tests are performed on each rope. The effects of the type of rope, drop height, drop weight, whether the rope has been subjected to static precycling, and the number of previous dynamic tests are examined. A mathematical model is proposed for the rope force as a function of the displacement and velocity of the weight.

  2. Triggered Snap-Through of Bistable Shells

    Science.gov (United States)

    Cai, Yijie; Huang, Shicheng; Trase, Ian; Hu, Nan; Chen, Zi

    Elastic bistable shells are common structures in nature and engineering, such as the lobes of the Venus flytrap or the surface of a toy jumping poppers. Despite their ubiquity, the parameters that control the bistability of such structures are not well understood. In this study, we explore how the geometrical features of radially symmetric elastic shells affect the shape and potential energy of a shell's stable states, and how to tune certain parameters in order to generate a snap-through transition from a convex semi-stable state to concave stable state. We fabricated a series of elastic shells with varying geometric parameters out of silicone rubber and measured the resulting potential energy in the semi-stable state. Finite element simulations were also conducted in order to determine the deformation and stress in the shells during snap-through. It was found that the energy of the semi-stable state is controlled by only two geometric parameters and a dimensionless ratio. We also noted two distinct transitions during snap-through, one between monostability and semi-bistability (the state a popper toy is in before it snaps-through and jumps), and a second transition between semi-bistability and true bistability. This work shows that it is possible to use a set of simple parameters to tailor the energy landscape of an elastic shell in order to generate complex trigger motions for their potential use in smart applications. Z.C. acknowledge support from Society in Science-Branco Weiss Fellowship, administered by ETH Zurich.

  3. Vortex formation with a snapping shrimp claw.

    Science.gov (United States)

    Hess, David; Brücker, Christoph; Hegner, Franziska; Balmert, Alexander; Bleckmann, Horst

    2013-01-01

    Snapping shrimp use one oversized claw to generate a cavitating high speed water jet for hunting, defence and communication. This work is an experimental investigation about the jet generation. Snapping shrimp (Alpheus-bellulus) were investigated by using an enlarged transparent model reproducing the closure of the snapper claw. Flow inside the model was studied using both High-Speed Particle Image Velocimetry (HS-PIV) and flow visualization. During claw closure a channel-like cavity was formed between the plunger and the socket featuring a nozzle-type contour at the orifice. Closing the mechanism led to the formation of a leading vortex ring with a dimensionless formation number of approximate ΔT*≈4. This indicates that the claw might work at maximum efficiency, i.e. maximum vortex strength was achieved by a minimum of fluid volume ejected. The subsequent vortex cavitation with the formation of an axial reentrant jet is a reasonable explanation for the large penetration depth of the water jet. That snapping shrimp can reach with their claw-induced flow. Within such a cavitation process, an axial reentrant jet is generated in the hollow cylindrical core of the cavitated vortex that pushes the front further downstream and whose length can exceed the initial jet penetration depth by several times.

  4. Vortex formation with a snapping shrimp claw.

    Directory of Open Access Journals (Sweden)

    David Hess

    Full Text Available Snapping shrimp use one oversized claw to generate a cavitating high speed water jet for hunting, defence and communication. This work is an experimental investigation about the jet generation. Snapping shrimp (Alpheus-bellulus were investigated by using an enlarged transparent model reproducing the closure of the snapper claw. Flow inside the model was studied using both High-Speed Particle Image Velocimetry (HS-PIV and flow visualization. During claw closure a channel-like cavity was formed between the plunger and the socket featuring a nozzle-type contour at the orifice. Closing the mechanism led to the formation of a leading vortex ring with a dimensionless formation number of approximate ΔT*≈4. This indicates that the claw might work at maximum efficiency, i.e. maximum vortex strength was achieved by a minimum of fluid volume ejected. The subsequent vortex cavitation with the formation of an axial reentrant jet is a reasonable explanation for the large penetration depth of the water jet. That snapping shrimp can reach with their claw-induced flow. Within such a cavitation process, an axial reentrant jet is generated in the hollow cylindrical core of the cavitated vortex that pushes the front further downstream and whose length can exceed the initial jet penetration depth by several times.

  5. Dynamic ultrasound of the external snapping hip syndrome

    International Nuclear Information System (INIS)

    Choi, Yun Sun; Song, Baek Yong; Paik, Sang Hyun; Lee, Tae Gyu; Yoon, Yong Kyu; Lee, Sung Moon

    2002-01-01

    Snapping hip syndrome has been described as a hip pain accompanied by an audible snapping during motion of the hip or while walking. The variable causes of its external, internal, and intra-articular origins have been described. The most common extemal snapping hip has been associated with a thickened posterior border of the iliotibial band or of the anterior border of the gluteus maximus muscle slipping over the greater trochanter. The aim of this study was to evaluate the dynamic ultrasound findings of external snapping hip syndrome with review of the literature. We studied 5 patients (7 cases) with external snapping hip and pain over the greater trochanter during walking or hip motion (3 males and 2 females, age range, 14-32 years; mean, 19 years). Two patients reported bilateral snapping hips.

  6. SnapShot: Phosphoregulation of Mitosis.

    Science.gov (United States)

    Burgess, Andrew; Vuong, Jenny; Rogers, Samuel; Malumbres, Marcos; O'Donoghue, Seán I

    2017-06-15

    During mitosis, a cell divides its duplicated genome into two identical daughter cells. This process must occur without errors to prevent proliferative diseases (e.g., cancer). A key mechanism controlling mitosis is the precise timing of more than 32,000 phosphorylation and dephosphorylation events by a network of kinases and counterbalancing phosphatases. The identity, magnitude, and temporal regulation of these events have emerged recently, largely from advances in mass spectrometry. Here, we show phosphoevents currently believed to be key regulators of mitosis. For an animated version of this SnapShot, please see http://www.cell.com/cell/enhanced/odonoghue2. Copyright © 2017. Published by Elsevier Inc.

  7. A document review to characterize Atomic International SNAP fuels shipped to INEL 1966--1973

    International Nuclear Information System (INIS)

    Wahnschaffe, S.D.; Lords, R.E.; Kneff, D.W.; Nagel, W.E.; Pearlman, H.; Schaubert, V.J.

    1995-09-01

    This report provides the results of a document search and review study to obtain information on the spent fuels for the following six Nuclear Auxiliary Power (SNAP) reactor cores now stored at the Idaho National Engineering Laboratory (INEL): SNAP-2 Experimental Reactor, SNAP-2 Development Reactor, SNAP-10A Ground Test Reactor, SNAP-8 Experimental Reactor, SNAP-8 Development Reactor, and Shield Test Reactor. The report also covers documentation on SNAP fuel materials from four in-pile materials tests: NAA-82-1, NAA-115-2, NAA-117-1, and NAA-121. Pieces of these fuel materials are also stored at INEL as part of the SNAP fuel shipments

  8. Snapping turtles, a biological screen for PCB's

    Energy Technology Data Exchange (ETDEWEB)

    Olafsson, P.G.; Bryan, A.M.; Bush, B.; Stone, W.

    1983-01-01

    Snapping turtles are capable of storing extremely high concentration of organochlorine compounds in their fat without any apparent detrimental effect. This tolerance, to high bioconcentration, permits a wide gradation between the extremes in pollution levels and facilitates the detection of extremely toxic substances present in trace amounts. Consequently snapping turtles provide an excellent biological screen for these compounds.

  9. Extending the accuracy of the SNAP interatomic potential form

    Science.gov (United States)

    Wood, Mitchell A.; Thompson, Aidan P.

    2018-06-01

    The Spectral Neighbor Analysis Potential (SNAP) is a classical interatomic potential that expresses the energy of each atom as a linear function of selected bispectrum components of the neighbor atoms. An extension of the SNAP form is proposed that includes quadratic terms in the bispectrum components. The extension is shown to provide a large increase in accuracy relative to the linear form, while incurring only a modest increase in computational cost. The mathematical structure of the quadratic SNAP form is similar to the embedded atom method (EAM), with the SNAP bispectrum components serving as counterparts to the two-body density functions in EAM. The effectiveness of the new form is demonstrated using an extensive set of training data for tantalum structures. Similar to artificial neural network potentials, the quadratic SNAP form requires substantially more training data in order to prevent overfitting. The quality of this new potential form is measured through a robust cross-validation analysis.

  10. Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

    Energy Technology Data Exchange (ETDEWEB)

    Wasik, Anita A.; Dumont, Vincent [Department of Pathology, University of Helsinki, 00014 Helsinki (Finland); Tienari, Jukka [Department of Pathology, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, 05850 Hyvinkää (Finland); Nyman, Tuula A. [Institute of Biotechnology, University of Helsinki, 00014 Helsinki (Finland); Fogarty, Christopher L.; Forsblom, Carol; Lehto, Markku [Folkhälsan Institute of Genetics, Folkhälsan Research Center, 00290 Helsinki (Finland); Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, 000290 Helsinki (Finland); Diabetes& Obesity Research Program, Research Program´s Unit, 00014 University of Helsinki (Finland); Lehtonen, Eero [Department of Pathology, University of Helsinki, 00014 Helsinki (Finland); Laboratory Animal Centre, University of Helsinki, 00014 Helsinki (Finland); Groop, Per-Henrik [Folkhälsan Institute of Genetics, Folkhälsan Research Center, 00290 Helsinki (Finland); Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, 000290 Helsinki (Finland); Diabetes& Obesity Research Program, Research Program´s Unit, 00014 University of Helsinki (Finland); Baker IDI Heart & Diabetes Institute, 3004 Melbourne (Australia); Lehtonen, Sanna, E-mail: sanna.h.lehtonen@helsinki.fi [Department of Pathology, University of Helsinki, 00014 Helsinki (Finland)

    2017-01-15

    Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex. We observed that knockdown of NMHC-IIA decreases insulin-stimulated glucose uptake into podocytes. Both septin 7 and NM-IIA associate with SNAP23, a SNARE protein involved in GLUT4 storage vesicle (GSV) docking and fusion with the plasma membrane. We observed that insulin decreases the level of septin 7 and increases the activity of NM-IIA in the SNAP23 complex, as visualized by increased phosphorylation of myosin regulatory light chain. Also knockdown of septin 7 increases the activity of NM-IIA in the complex. The activity of NM-IIA is increased in diabetic rat glomeruli and cultured human podocytes exposed to macroalbuminuric sera from patients with type 1 diabetes. Collectively, the data suggest that the activity of NM-IIA in the SNAP23 complex plays a key role in insulin-stimulated glucose uptake into podocytes. Furthermore, we observed that septin 7 reduces the activity of NM-IIA in the SNAP23 complex and thereby hinders GSV docking and fusion with the plasma membrane. - Highlights: • Septin 7, nonmuscle myosin heavy chain IIA (NMHC-IIA) and SNAP23 form a complex. • Knockdown of septin 7 increases NM-IIA activity in the SNAP23 complex. • Insulin decreases septin 7 level and increases NM-IIA activity in the SNAP23 complex. • Septin 7 hinders GSV docking/fusion by reducing NM-IIA activity in the SNAP23 complex.

  11. Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

    International Nuclear Information System (INIS)

    Wasik, Anita A.; Dumont, Vincent; Tienari, Jukka; Nyman, Tuula A.; Fogarty, Christopher L.; Forsblom, Carol; Lehto, Markku; Lehtonen, Eero; Groop, Per-Henrik; Lehtonen, Sanna

    2017-01-01

    Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex. We observed that knockdown of NMHC-IIA decreases insulin-stimulated glucose uptake into podocytes. Both septin 7 and NM-IIA associate with SNAP23, a SNARE protein involved in GLUT4 storage vesicle (GSV) docking and fusion with the plasma membrane. We observed that insulin decreases the level of septin 7 and increases the activity of NM-IIA in the SNAP23 complex, as visualized by increased phosphorylation of myosin regulatory light chain. Also knockdown of septin 7 increases the activity of NM-IIA in the complex. The activity of NM-IIA is increased in diabetic rat glomeruli and cultured human podocytes exposed to macroalbuminuric sera from patients with type 1 diabetes. Collectively, the data suggest that the activity of NM-IIA in the SNAP23 complex plays a key role in insulin-stimulated glucose uptake into podocytes. Furthermore, we observed that septin 7 reduces the activity of NM-IIA in the SNAP23 complex and thereby hinders GSV docking and fusion with the plasma membrane. - Highlights: • Septin 7, nonmuscle myosin heavy chain IIA (NMHC-IIA) and SNAP23 form a complex. • Knockdown of septin 7 increases NM-IIA activity in the SNAP23 complex. • Insulin decreases septin 7 level and increases NM-IIA activity in the SNAP23 complex. • Septin 7 hinders GSV docking/fusion by reducing NM-IIA activity in the SNAP23 complex.

  12. Amplitude-integrated electroencephalographic activity is suppressed in preterm infants with high scores on illness severity

    NARCIS (Netherlands)

    ter Horst, Hendrik J.; Jongbloed-Pereboom, Marjolein; van Eykern, Leo A.; Bos, Arend F.

    Background: The neonatal acute physiology score. SNAP-II, reflects the severity of illness in newborns. In term newborns, amplitude integrated EEG (aEEG), is depressed following asphyxia. In preterm infants aEEG is discontinuous, and therefore more difficult to assess compared to term infants. Aims:

  13. Snapping turtles (Chelydra serpentina) as biomonitors of lead contamination of the Big River in Missouri`s Old Lead Belt

    Energy Technology Data Exchange (ETDEWEB)

    Overmann, S.R.; Krajicek, J.J. [Southeast Missouri State Univ., Cape Girardeau, MO (United States). Dept. of Biology

    1995-04-01

    The usefulness of common snapping turtles (Chelydra serpentina) as biomonitors of lead (Pb) contamination of aquatic ecosystems was assessed. Thirty-seven snapping turtles were collected from three sites on the Big River, an Ozarkian stream contaminated with Pb mine tailings. Morphometric measurements, tissue Pb concentrations (muscle, blood, bone, carapace, brain, and liver), {delta}-aminolevulinic acid dehydratase ({delta}-ALAD) activity, hematocrit, hemoglobin, plasma glucose, osmolality, and chloride ion content were measured. The data showed no effects of Pb contamination on capture success or morphological measurements. Tissue Pb concentrations were related to capture location. Hematocrit, plasma osmolality, plasma glucose, and plasma chloride ion content were not significantly different with respect to capture location. The {delta}-ALAD activity levels were decreased in turtles taken from contaminated sites. Lead levels in the Big River do not appear to be adversely affecting the snapping turtles of the river. Chelydra serpentina is a useful species for biomonitoring of Pb-contaminated aquatic environments.

  14. SNAP 19 Viking RTG mission performance

    International Nuclear Information System (INIS)

    Brittain, W.M.

    1976-01-01

    The Viking-75 mission utilized the August/September 1975 opportunity to launch two spacecrafts to Mars for arrival in 1976 after about a one-year transit period. On arrival, each spacecraft, consisting of an orbiter and lander, will be placed in Mars orbit, with each lander subsequently descending from orbit to a soft-landing on the Martian surface. Two SNAP 19 RTG's (radioisotope thermoelectric generators) provide the primary source of electrical power and means of thermal control for each Viking lander. The RTG's will be switched on-load just prior to separation of the lander from the orbiter for checkout of the lander, and will remain on-load during entry and the remainder of the 90-day minimum surface mission

  15. SNAP sky background at the north ecliptic pole

    International Nuclear Information System (INIS)

    Aldering, Greg

    2002-01-01

    I summarize the extant direct and indirect data on the sky background SNAP will see at the North Ecliptic Pole over the wavelength range 0.4 < λ < 1.7 (micro)m. At the spatial resolution of SNAP the sky background due to stars and galaxies is resolved, so the only source considered is zodiacal light. Several models are explored to provide interpolation in wavelength between the broadband data from HST and COBE observations. I believe the input data are now established well enough that the accuracy of the sky background presented here is sufficient for SNAP simulations, and that it will stand up to scrutiny by reviewers

  16. Cutaneous fibroma in a captive common snapping turtle (Chelydra serpentina).

    Science.gov (United States)

    Gonzales-Viera, O; Bauer, G; Bauer, A; Aguiar, L S; Brito, L T; Catão-Dias, J L

    2012-11-01

    An adult female common snapping turtle (Chelydra serpentina) had a mass on the plantar surface of the right forelimb that was removed surgically. Microscopical examination revealed many spindle cells with mild anisocytosis and anisokaryosis and a surrounding collagenous stroma. There were no mitoses. Immunohistochemistry showed that the spindle cells expressed vimentin, but not desmin. A diagnosis of cutaneous fibroma was made. Tumours are reported uncommonly in chelonian species. Cutaneous fibroma has been diagnosed in an alligator snapping turtle (Macrochelys temminckii), but not previously in a common snapping turtle. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  17. Quantitative mass spectrometry reveals changes in SNAP-25 isoforms in schizophrenia

    Science.gov (United States)

    Barakauskas, Vilte E; Moradian, Annie; Barr, Alasdair M.; Beasley, Clare L; Rosoklija, Gorazd; Mann, J John; Ilievski, Boro; Stankov, Aleksandar; Dwork, Andrew J; Falkai, Peter; Morin, Gregg B; Honer, William G

    2016-01-01

    SNAP-25 and syntaxin are presynaptic terminal SNARE proteins altered in amount and function in schizophrenia. In the ventral caudate, we observed 32% lower SNAP-25 and 26% lower syntaxin, but greater interaction between the two proteins using an in vitro assay. SNAP-25 has two isoforms, SNAP-25A and B, differing by only 9 amino acids, but with different effects on neurotransmission. A quantitative mass spectrometry assay was developed to measure total SNAP-25, and proportions of SNAP-25A and B. The assay had a good linear range (50- to 150-fold) and coefficient of variation (4.5%). We studied ventral caudate samples from patients with schizophrenia (n=15) previously reported to have lower total SNAP-25 than controls (n=13). We confirmed 27% lower total SNAP-25 in schizophrenia, and observed 31% lower SNAP-25A (P = 0.002) with 20% lower SNAP-25B amounts (P = 0.10). Lower SNAP-25A amount correlated with greater SNAP-25-syntaxin protein-protein interactions (r = -0.41, P = 0.03); the level of SNAP-25B did not. Administration of haloperidol or clozapine to rats did not mimic the changes found in schizophrenia. The findings suggest that lower levels of SNAP-25 in schizophrenia may represent a greater effect of the illness on the SNAP-25A isoform. This in turn could contribute to the greater interaction between SNAP25 and syntaxin, and possibly disturb neurotransmission in the illness. PMID:26971072

  18. The amino acid sequence of snapping turtle (Chelydra serpentina) ribonuclease

    NARCIS (Netherlands)

    Beintema, Jacob; Broos, Jaap; Meulenberg, Janneke; Schüller, Cornelis

    1985-01-01

    Snapping turtle (Chelydra serpentina) ribonuclease was isolated from pancreatic tissue. Turtle ribonuclease binds much more weakly to the affinity chromatography matrix used than mammalian ribonucleases. The amino acid sequence was determined from overlapping peptides obtained from three different

  19. SNAP-3D: a three-dimensional neutron diffusion code

    International Nuclear Information System (INIS)

    McCallien, C.W.J.

    1975-10-01

    A preliminary report is presented describing the data requirements of a one- two- or three-dimensional multi-group diffusion code, SNAP-3D. This code is primarily intended for neutron diffusion calculations but it can also carry out gamma calculations if the diffuse approximation is accurate enough. It is suitable for fast and thermal reactor core calculations and for shield calculations. It is assumed the reader is familiar with the older, two-dimensional code SNAP and can refer to the report [TRG-Report-1990], describing it. The present report concentrates on the enhancements to SNAP that have been made to produce the three-dimensional version, SNAP-3D, and is intended to act a a guide on data preparation until a single, comprehensive report can be published. (author)

  20. Combined SAFE/SNAP approach to safeguards evaluation

    International Nuclear Information System (INIS)

    Engi, D.; Chapman, L.D.; Grant, F.H.; Polito, J.

    1980-01-01

    The scope of a safeguards evaluation model can efficiently address one of two issues: (1) global safeguards effectiveness or (2) vulnerability analysis for individual scenarios. The Safeguards Automated Facility Evaluation (SAFE) focuses on the first issue, while the Safeguards Network Analysis Procedure (SNAP) is directed towards the second. A combined SAFE/SNAP approach to the problem of safeguards evaluation is described and illustrated through an example. 4 refs

  1. SNAP: A General Purpose Network Analysis and Graph Mining Library.

    Science.gov (United States)

    Leskovec, Jure; Sosič, Rok

    2016-10-01

    Large networks are becoming a widely used abstraction for studying complex systems in a broad set of disciplines, ranging from social network analysis to molecular biology and neuroscience. Despite an increasing need to analyze and manipulate large networks, only a limited number of tools are available for this task. Here, we describe Stanford Network Analysis Platform (SNAP), a general-purpose, high-performance system that provides easy to use, high-level operations for analysis and manipulation of large networks. We present SNAP functionality, describe its implementational details, and give performance benchmarks. SNAP has been developed for single big-memory machines and it balances the trade-off between maximum performance, compact in-memory graph representation, and the ability to handle dynamic graphs where nodes and edges are being added or removed over time. SNAP can process massive networks with hundreds of millions of nodes and billions of edges. SNAP offers over 140 different graph algorithms that can efficiently manipulate large graphs, calculate structural properties, generate regular and random graphs, and handle attributes and meta-data on nodes and edges. Besides being able to handle large graphs, an additional strength of SNAP is that networks and their attributes are fully dynamic, they can be modified during the computation at low cost. SNAP is provided as an open source library in C++ as well as a module in Python. We also describe the Stanford Large Network Dataset, a set of social and information real-world networks and datasets, which we make publicly available. The collection is a complementary resource to our SNAP software and is widely used for development and benchmarking of graph analytics algorithms.

  2. SNAP: a tool for nuclear physical protection system modeling

    International Nuclear Information System (INIS)

    Engi, D.; Grant, F.H. III.

    1979-10-01

    Nuclear safeguards systems are concerned, in part, with the physical protection of nuclear materials. The function of a physical protection system is to define the facility against adversary activities which could lead to theft of nuclear material or sabotage resulting in a radiological release. The Safeguards Network Analysis Procedure (SNAP) provides a convenient and standard analysis methodology for the evaluation of physical protection system analysis. This paper describes a detailed application of SNAP to a hypothetical nuclear facility

  3. On the presence of plutonium in Madagascar following the SNAP-9A satellite failure.

    Science.gov (United States)

    Rääf, C; Holm, E; Rabesiranana, N; Garcia-Tenorio, R; Chamizo, E

    2017-10-01

    This study examined the 238 Pu and 239+240 Pu activity concentration and the 240 Pu/ 239 Pu atomic ratio in peat bogs sampled in 2012 from marshlands in central Madagascar. The purpose was to investigate the presence of plutonium isotopes, 238, 239, 240 Pu, from the 1964 satellite failure carrying a SNAP-9A radiothermal generator. With an average 238 Pu/ 239+240 Pu activity ratio of 0.165 ± 0.02 (decay corrected to 1964), the peat bogs in Madagascar exhibit similar values as the ones found in the southeastern African continent, except they are one order of magnitude higher than expected (0.025) from global fallout in the Southern Hemisphere. The 240 Pu/ 239 Pu atomic ratio showed a distinct decrease for layers dating back to the mid-1960s (down to 0.069 compared with an anticipated ratio of 0.17 for global fallout), indicating that the SNAP-9A failure also resulted in an elevated deposition of 239 Pu. The obtained results demonstrate that further Pu analysis in Madagascar and in southeastern continental Africa is necessary to fully account for the regional Pu deposition from the SNAP-9A event. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. The mobility of food retailers: How proximity to SNAP authorized food retailers changed in Atlanta during the Great Recession.

    Science.gov (United States)

    Shannon, Jerry; Bagwell-Adams, Grace; Shannon, Sarah; Lee, Jung Sun; Wei, Yangjiaxin

    2018-07-01

    Retailer mobility, defined as the shifting geographic patterns of retail locations over time, is a significant but understudied factor shaping neighborhood food environments. Our research addresses this gap by analyzing changes in proximity to SNAP authorized chain retailers in the Atlanta urban area using yearly data from 2008 to 2013. We identify six demographically similar geographic clusters of census tracts in our study area based on race and economic variables. We use these clusters in exploratory data analysis to identify how proximity to the twenty largest retail food chains changed during this period. We then use fixed effects models to assess how changing store proximity is associated with race, income, participation in SNAP, and population density. Our results show clear differences in geographic distribution between store categories, but also notable variation within each category. Increasing SNAP enrollment predicted decreased distances to almost all small retailers but increased distances to many large retailers. Our chain-focused analysis underscores the responsiveness of small retailers to changes in neighborhood SNAP participation and the value of tracking chain expansion and contraction in markets across time. Better understanding of retailer mobility and the forces that drive it can be a productive avenue for future research. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Synaptosomal Protein of 25 kDa (Snap25 Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients

    Directory of Open Access Journals (Sweden)

    Nasser M. Al-Daghri

    2016-01-01

    Full Text Available A possible role of Snap25 polymorphisms in type 2 diabetes mellitus (T2DM was evaluated by analyzing three SNPs within intron 1 in a region known to affect the gene expression in vitro. Genomic DNA from 1019 Saudi individuals (489 confirmed T2DM and 530 controls was genotyped for SNPs rs363039, rs363043, and rs363050 in Snap25 using the TaqMan Genotyping Assay. Significantly higher levels of fasting glucose and HbA1c were detected in T2DM patients carrying the rs363050 (AG/GG genotypes compared to the (AA genotype (f=4.41, df=1, and p=0.03 and f=5.31, df=1, and p=0.03, resp.. In these same patients, insulin levels were significantly decreased compared to the (AA individuals (f=7.29, df=1, and p=0.009. Significant associations were detected between rs363050 (AG/GG genotypes and increasing fasting glucose levels (p=0.01 and OR: 1.05, HbA1c levels (OR: 5.06 and p=0.02, and lower insulinemia (p=0.03 and OR: 0.95 in T2DM patients. The minor Snap25 rs363050 (G allele, which results in a reduced expression of Snap25, is associated with altered glycemic parameters in T2DM possibly because of reduced functionality in the exocytotic machinery leading to suboptimal release of insulin.

  6. Diphoton generalized distribution amplitudes

    International Nuclear Information System (INIS)

    El Beiyad, M.; Pire, B.; Szymanowski, L.; Wallon, S.

    2008-01-01

    We calculate the leading order diphoton generalized distribution amplitudes by calculating the amplitude of the process γ*γ→γγ in the low energy and high photon virtuality region at the Born order and in the leading logarithmic approximation. As in the case of the anomalous photon structure functions, the γγ generalized distribution amplitudes exhibit a characteristic lnQ 2 behavior and obey inhomogeneous QCD evolution equations.

  7. External Snapping Hip Syndrome: Emphasis on the MR Imaging

    International Nuclear Information System (INIS)

    Choi, Jung Eun; Lee, Bae Young; Sung, Mi Sook; Lee, Ki Haeng; Yoo, Won Jong; Lim, Hyun Wook; Chung, Myung Hee; Park, Jeong Mi; Kim, Jee Young

    2010-01-01

    The aim of this study is to evaluate the MR imaging features of patients with external snapping hip syndrome. We retrospectively reviewed 63 hip MR images. The images were analyzed according to the thickness and contour of the iliotibial band and the gluteus maximus, the presence of bone marrow edema, bursitis, joint effusion and other associated findings. The MR imaging of 22 hips with snapping hip syndrome depicted the causes of external snapping hip syndrome in twenty cases (90%). The MR imaging features of the snapping hip included thickening of the iliotibial band in twelve cases (55%) and/or thickening of the anterior band of the gluteus maximus in nineteen (86%), and a wavy contour of the iliotibial band or the anterior band of the gluteus maximus in ten cases (45%). These findings show a significant p value (<0.01). The majority of patients with snapping hip syndrome revealed thickening of the iliotibial band, thickening of the anterior band of the gluteus maximus and wavy contour of the those structures on MR imaging

  8. External Snapping Hip Syndrome: Emphasis on the MR Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jung Eun; Lee, Bae Young [Catholic University St. Paul' s Hospital, Seoul (Korea, Republic of); Sung, Mi Sook; Lee, Ki Haeng; Yoo, Won Jong; Lim, Hyun Wook; Chung, Myung Hee [Catholic University Bucheon St. Mary' s Hospital, Bucheon (Korea, Republic of); Park, Jeong Mi [Catholic University St. Mary' s Hospital, Seoul (Korea, Republic of); Kim, Jee Young [Catholic University St. Vincent' s Hospital, Suwon (Korea, Republic of)

    2010-02-15

    The aim of this study is to evaluate the MR imaging features of patients with external snapping hip syndrome. We retrospectively reviewed 63 hip MR images. The images were analyzed according to the thickness and contour of the iliotibial band and the gluteus maximus, the presence of bone marrow edema, bursitis, joint effusion and other associated findings. The MR imaging of 22 hips with snapping hip syndrome depicted the causes of external snapping hip syndrome in twenty cases (90%). The MR imaging features of the snapping hip included thickening of the iliotibial band in twelve cases (55%) and/or thickening of the anterior band of the gluteus maximus in nineteen (86%), and a wavy contour of the iliotibial band or the anterior band of the gluteus maximus in ten cases (45%). These findings show a significant p value (<0.01). The majority of patients with snapping hip syndrome revealed thickening of the iliotibial band, thickening of the anterior band of the gluteus maximus and wavy contour of the those structures on MR imaging.

  9. Snap-Through Buckling Problem of Spherical Shell Structure

    Directory of Open Access Journals (Sweden)

    Sumirin Sumirin

    2014-12-01

    Full Text Available This paper presents results of a numerical study on the nonlinear behavior of shells undergoing snap-through instability. This research investigates the problem of snap-through buckling of spherical shells applying nonlinear finite element analysis utilizing ANSYS Program. The shell structure was modeled by axisymmetric thin shell of finite elements. Shells undergoing snap-through buckling meet with significant geometric change of their physical configuration, i.e. enduring large deflections during their deformation process. Therefore snap-through buckling of shells basically is a nonlinear problem. Nonlinear numerical operations need to be applied in their analysis. The problem was solved by a scheme of incremental iterative procedures applying Newton-Raphson method in combination with the known line search as well as the arc- length methods. The effects of thickness and depth variation of the shell is taken care of by considering their geometrical parameter l. The results of this study reveal that spherical shell structures subjected to pressure loading experience snap-through instability for values of l≥2.15. A form of ‘turn-back’ of the load-displacement curve took place at load levels prior to the achievement of the critical point. This phenomenon was observed for values of l=5.0 to l=7.0.

  10. Full amplitude models of 15 day Cepheids

    International Nuclear Information System (INIS)

    Cogan, B.C.; Cox, A.N.; King, D.S.

    1980-01-01

    Numerical models of Cepheids have been computed with a range of effective temperatures and compositions. The amplitudes increase if the helium abundance increases or if the effective temperature decreases. The latter effect is contrary to observational data. The models also exhibit velocity amplitudes which are much lower than those observed

  11. Two Photon Distribution Amplitudes

    International Nuclear Information System (INIS)

    El Beiyad, M.; Pire, B.; Szymanowski, L.; Wallon, S.

    2008-01-01

    The factorization of the amplitude of the process γ*γ→γγ in the low energy and high photon virtuality region is demonstrated at the Born order and in the leading logarithmic approximation. The leading order two photon (generalized) distribution amplitudes exhibit a characteristic ln Q 2 behaviour and obey new inhomogeneous evolution equations

  12. Combined SAFE/SNAP approach to safeguards evaluation

    International Nuclear Information System (INIS)

    Engi, D.; Chapman, L.D.; Grant, F.H.; Polito, J.

    1980-01-01

    Generally, the scope of a safeguards evaluation model can efficiently address one of two issues, (1) global safeguards effectiveness, or (2) vulnerability analysis for individual scenarios. The Safeguards Automated Facility Evaluation (SAFE) focuses on (1) while the Safeguards Network Analysis Procedure (SNAP) is directed at (2). SAFE addresses (1) in that it considers the entire facility, i.e., the composite system of hardware and human components, in one global analysis. SNAP addresses (2) by providing a safeguards modeling symbology sufficiently flexible to represent quite complex scenarios from the standpoint of hardware interfaces while also accounting for a rich variety of human decision making. A combined SAFE/SNAP approach to the problem of safeguards evaluation is described and illustrated through an example

  13. Amplitudes, acquisition and imaging

    Energy Technology Data Exchange (ETDEWEB)

    Bloor, Robert

    1998-12-31

    Accurate seismic amplitude information is important for the successful evaluation of many prospects and the importance of such amplitude information is increasing with the advent of time lapse seismic techniques. It is now widely accepted that the proper treatment of amplitudes requires seismic imaging in the form of either time or depth migration. A key factor in seismic imaging is the spatial sampling of the data and its relationship to the imaging algorithms. This presentation demonstrates that acquisition caused spatial sampling irregularity can affect the seismic imaging and perturb amplitudes. Equalization helps to balance the amplitudes, and the dealing strategy improves the imaging further when there are azimuth variations. Equalization and dealiasing can also help with the acquisition irregularities caused by shot and receiver dislocation or missing traces. 2 refs., 2 figs.

  14. Color guided amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Broedel, Johannes [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University, Stanford, CA (United States); Dixon, Lance J. [SLAC National Accelerator Laboratory, Stanford University, Stanford, CA (United States)

    2012-07-01

    Amplitudes in gauge thoeries obtain contributions from color and kinematics. While these two parts of the amplitude seem to exhibit different symmetry structures, it turns out that they can be reorganized in a way to behave equally, which leads to the so-called color-kinematic dual representations of amplitudes. Astonishingly, the existence of those representations allows squaring to related gravitational theories right away. Contrary to the Kawaii-Levellen-Tye relations, which have been used to relate gauge theories and gravity previously, this method is applicable not only to tree amplitudes but also at loop level. In this talk, the basic technique is introduced followed by a discussion of the existence of color-kinematic dual representations for amplitudes derived from gauge theory actions which are deformed by higher-operator insertions. In addition, it is commented on the implications for deformed gravitational theories.

  15. SNAP: Small Next-generation Atmospheric Probe Concept

    Science.gov (United States)

    Sayanagi, K. M.; Dillman, R. A.; Atkinson, D. H.; Li, J.; Saikia, S.; Simon, A. A.; Spilker, T. R.; Wong, M. H.; Hope, D.

    2017-12-01

    We present a concept for a small, atmospheric probe that could be flexibly added to future missions that orbit or fly-by a giant planet as a secondary payload, which we call the Small Next-generation Atmospheric Probe (SNAP). SNAP's main scientific objectives are to determine the vertical distribution of clouds and cloud-forming chemical species, thermal stratification, and wind speed as a function of depth. As a case study, we present the advantages, cost and risk of adding SNAP to the future Uranus Orbiter and Probe flagship mission; in combination with the mission's main probe, SNAP would perform atmospheric in-situ measurements at a second location, and thus enable and enhance the scientific objectives recommended by the 2013 Planetary Science Decadal Survey and the 2014 NASA Science Plan to determine atmospheric spatial variabilities. We envision that the science objectives can be achieved with a 30-kg entry probe 0.5m in diameter (less than half the size of the Galileo probe) that reaches 5-bar pressure-altitude and returns data to Earth via the carrier spacecraft. As the baseline instruments, the probe will carry an Atmospheric Structure Instrument (ASI) that measures the temperature, pressure and acceleration, a carbon nanotube-based NanoChem atmospheric composition sensor, and an Ultra-Stable Oscillator (USO) to conduct a Doppler Wind Experiment (DWE). We also catalog promising technologies currently under development that will strengthen small atmospheric entry probe missions in the future. While SNAP is applicable to multiple planets, we examine the feasibility, benefits and impacts of adding SNAP to the Uranus Orbiter and Probe flagship mission. Our project is supported by NASA PSDS3 grant NNX17AK31G.

  16. Territorial aggressiveness and predation: two possible origins of snapping in the ant Plectroctena minor.

    Science.gov (United States)

    Dejean, Alain; Suzzoni, Jean-Pierre; Schatz, Bertrand; Orivel, Jérôme

    2002-07-01

    Plectroctena minor workers have long mandibles that can snap and deliver a sharp blow to intruders or prey, stunning or killing them. Encounters between homocolonial P. minor workers separated for 24 h or 15 days never resulted in snapping, while this behaviour was always noted during encounters between heterocolonial workers on neutral arenas or on the territory of a colony. In the latter case, only the aliens, that generally tried to escape, were snapped at. Snapping also occurred during encounters with workers belonging to sympatric ponerine species. During predation, the percentages of snapping varied according to prey nature, suggesting prey discrimination. Termite soldiers were always snapped at, while other prey were more often snapped close to rather than far from the nest entrances, indicating an intermingling of territorial aggressiveness and predatory behaviour. We discuss the adaptive value of snapping for hunting in galleries.

  17. Beyond velocity and acceleration: jerk, snap and higher derivatives

    Science.gov (United States)

    Eager, David; Pendrill, Ann-Marie; Reistad, Nina

    2016-11-01

    The higher derivatives of motion are rarely discussed in the teaching of classical mechanics of rigid bodies; nevertheless, we experience the effect not only of acceleration, but also of jerk and snap. In this paper we will discuss the third and higher order derivatives of displacement with respect to time, using the trampolines and theme park roller coasters to illustrate this concept. We will also discuss the effects on the human body of different types of acceleration, jerk, snap and higher derivatives, and how they can be used in physics education to further enhance the learning and thus the understanding of classical mechanics concepts.

  18. Snapping wrist due to multiple accessory tendon of first extensor compartment

    Directory of Open Access Journals (Sweden)

    S. Dhiyaneswaran Subramaniyam

    2018-01-01

    Conclusion: There are various causes for snapping wrist syndrome. Multiple accessory tendon can also cause snapping as shown in this case report. Moreover am presenting this case to highlight the diagnostic failure with non dynamic radiological investigation and to consider multiple accessory tendon as differential diagnosis for snapping wrist syndrome. Also suggest dynamic study could be a better choice of investigation to diagnosis snapping syndrome. First compartment tunnel release with few accessory tendon slip tenotomy gives good result.

  19. 78 FR 52899 - Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility...

    Science.gov (United States)

    2013-08-27

    ... food choices, access to food, and retailer operations. Listening session attendees will be provided... food, be eligible to participate in SNAP? 10. Restaurants are generally prohibited from being SNAP... in an area where no store meets basic eligibility criteria for SNAP authorization, how should FNS...

  20. Finite Amplitude Ocean Waves

    Indian Academy of Sciences (India)

    IAS Admin

    wavelength, they are called shallow water waves. In the ... Deep and intermediate water waves are dispersive as the velocity of these depends on wavelength. This is not the ..... generation processes, the finite amplitude wave theories are very ...

  1. Real topological string amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Narain, K.S. [The Abdus Salam International Centre for Theoretical Physics (ICTP),Strada Costiera 11, Trieste, 34151 (Italy); Piazzalunga, N. [Simons Center for Geometry and Physics, State University of New York,Stony Brook, NY, 11794-3636 (United States); International School for Advanced Studies (SISSA) and INFN, Sez. di Trieste,via Bonomea 265, Trieste, 34136 (Italy); Tanzini, A. [International School for Advanced Studies (SISSA) and INFN, Sez. di Trieste,via Bonomea 265, Trieste, 34136 (Italy)

    2017-03-15

    We discuss the physical superstring correlation functions in type I theory (or equivalently type II with orientifold) that compute real topological string amplitudes. We consider the correlator corresponding to holomorphic derivative of the real topological amplitude G{sub χ}, at fixed worldsheet Euler characteristic χ. This corresponds in the low-energy effective action to N=2 Weyl multiplet, appropriately reduced to the orientifold invariant part, and raised to the power g{sup ′}=−χ+1. We show that the physical string correlator gives precisely the holomorphic derivative of topological amplitude. Finally, we apply this method to the standard closed oriented case as well, and prove a similar statement for the topological amplitude F{sub g}.

  2. Effects of strength training on mechanomyographic amplitude

    International Nuclear Information System (INIS)

    DeFreitas, Jason M; Beck, Travis W; Stock, Matt S

    2012-01-01

    The aim of the present study was to determine if the patterns of mechanomyographic (MMG) amplitude across force would change with strength training. Twenty-two healthy men completed an 8-week strength training program. During three separate testing visits (pre-test, week 4, and week 8), the MMG signal was detected from the vastus lateralis as the subjects performed isometric step muscle actions of the leg extensors from 10–100% of maximal voluntary contraction (MVC). During pre-testing, the MMG amplitude increased linearly with force to 66% MVC and then plateaued. Conversely, weeks 4 and 8 demonstrated an increase in MMG amplitude up to ∼85% of the subject's original MVC before plateauing. Furthermore, seven of the ten force levels (30–60% and 80–100%) showed a significant decrease in mean MMG amplitude values after training, which consequently led to a decrease in the slope of the MMG amplitude/force relationship. The decreases in MMG amplitude at lower force levels are indicative of hypertrophy, since fewer motor units would be required to produce the same absolute force if the motor units increased in size. However, despite the clear changes in the mean values, analyses of individual subjects revealed that only 55% of the subjects demonstrated a significant decrease in the slope of the MMG amplitude/force relationship. (paper)

  3. Snapping scapular syndrome secondary to rib intramedullary fixation device

    Directory of Open Access Journals (Sweden)

    Ezequiel E. Zaidenberg

    2015-01-01

    Conclusion: Surgeons should pay attention to any protrusion of intramedullary rib implants, especially in the evaluation of routine X-rays following surgical treatment. We should be aware of the possibility of this rare cause of snapping scapula syndrome to avoid delayed diagnosis and consider removing the implant will resolve the pain.

  4. multiple disease resistance in snap bean genotypes in kenya

    African Journals Online (AJOL)

    Prof. Adipala Ekwamu

    Department of Plant Science and Crop Protection, University of Nairobi, P. O. Box 29053- ... Agriculture (CIAT), National Agricultural Research Laboratories Institute, ... Climbing snap bean lines had thick pods that could reduce pod quality. ... MATERIALS AND METHODS ... were harvested in sterile distilled water and spore.

  5. Reconceiving SNAP: Is Nutritional Assistance Really Income Support?

    Science.gov (United States)

    Besharov, Douglas J.

    2016-01-01

    Since its creation, the Supplemental Nutrition Assistance Program (SNAP) has changed from an antihunger program to an income-supplementation program. Because the program (and its predecessor Food Stamp Program) was not designed for this purpose, the result is a program that has many unintended and, many believe, negative effects. The key challenge…

  6. The 'Snap Vote' of 462/1 BCE

    DEFF Research Database (Denmark)

    Thomsen, Christian Ammitzbøll

    2014-01-01

    still holds that the absence of 4,000 politically conservative hoplites under the leadership of Kimon paved the way for radical democratic reform - championed by Ephialtes and voted through the Athenian assembly in a ‘snap vote’ by the mass of democratic rowers who remained in the city. This note re...

  7. Intra-articular lipoma causing snapping in the patellofemoral joint

    International Nuclear Information System (INIS)

    Yilmaz, E.; Karakurt, L.; Yildirim, H.; Ozercan, R.

    2007-01-01

    Intra-articular lipoma is an exceedingly rare diagnosis. We identified a lipoma that was seated in the retropatellar are and caused snapping of the patella during flexion of the knee joint. The tumor was easily and totally excised under arthroscopic guidance after the thin pedicle was cut. (author)

  8. Directed supramolecular surface assembly of SNAP-tag fusion proteins

    NARCIS (Netherlands)

    Uhlenheuer, D.A.; Wasserberg, D.; Haase, C.; Nguyen, H.; Schenkel, J.H.; Huskens, J.; Ravoo, B.J.; Jonkheijm, P.; Brunsveld, L.

    2012-01-01

    Supramolecular assembly of proteins on surfaces and vesicles was investigated by site-selective incorporation of a supramolecular guest element on proteins. Fluorescent proteins were site-selectively labeled with bisadamantane by SNAP-tag technology. The assembly of the bisadamantane functionalized

  9. Immobilization of ferrocene-modified SNAP-fusion proteins

    NARCIS (Netherlands)

    Wasserberg, D.; Uhlenheuer, D.; Neirynck, P.; Neirynck, Pauline; Cabanas Danés, Jordi; Schenkel, J.H.; Ravoo, B.J.; An, Q.; Huskens, Jurriaan; Milroy, L.G.; Brunsveld, Luc; Jonkheijm, Pascal

    2013-01-01

    The supramolecular assembly of proteins on surfaces has been investigated via the site-selective incorporation of a supramolecular moiety on proteins. To this end, fluorescent proteins have been site-selectively labeled with ferrocenes, as supramolecular guest moieties, via SNAP-tag technology. The

  10. Directed Supramolecular Surface Assembly of SNAP-tag Fusion Proteins

    NARCIS (Netherlands)

    Uhlenheuer, D.A.; Wasserberg, D.; Haase, C.; Nguyen, Hoang D.; Schenkel, J.H.; Huskens, Jurriaan; Ravoo, B.J.; Jonkheijm, Pascal; Brunsveld, Luc

    2012-01-01

    Supramolecular assembly of proteins on surfaces and vesicles was investigated by site-selective incorporation of a supramolecular guest element on proteins. Fluorescent proteins were site-selectively labeled with bisadamantane by SNAP-tag technology. The assembly of the bisadamantane functionalized

  11. SNAP/SOS: a package for simulating and analyzing safeguards systems

    International Nuclear Information System (INIS)

    Grant, F.H. III; Polito, J.; Sabuda, J.

    1983-01-01

    The effective analysis of safeguards systems at nuclear facilities requires significant effort. The Safeguards Network Analysis Procedure (SNAP) and the SNAP Operating System (SOS) reduce that effort to a manageable level. SNAP provides a detailed analysis of site safeguards for tactical evaluation. SOS helps the analyst organize and manage the SNAP effort effectively. SOS provides a database for model storage, automatic model generation, and computer graphics. The SOS/SNAP combination is a working example of a simulation system including executive-level control, database system, and facilities for model creation, editing, and output analysis

  12. Kinesin-1 plays a role in transport of SNAP-25 to the plasma membrane

    Energy Technology Data Exchange (ETDEWEB)

    Morton, April M.; Cunningham, Anthony L. [Centre for Virus Research, Westmead Millennium Institute, The University of Sydney and Westmead Hospital, Westmead, NSW 2145 (Australia); Diefenbach, Russell J., E-mail: russell_diefenbach@wmi.usyd.edu.au [Centre for Virus Research, Westmead Millennium Institute, The University of Sydney and Westmead Hospital, Westmead, NSW 2145 (Australia)

    2010-01-01

    The cellular molecular motor kinesin-1 mediates the microtubule-dependent transport of a range of cargo. We have previously identified an interaction between the cargo-binding domain of kinesin-1 heavy chain KIF5B and the membrane-associated SNARE proteins SNAP-25 and SNAP-23. In this study we further defined the minimal SNAP-25 binding domain in KIF5B to residues 874-894. Overexpression of a fragment of KIF5B (residues 594-910) resulted in significant colocalization with SNAP-25 with resulting blockage of the trafficking of SNAP-25 to the periphery of cells. This indicates that kinesin-1 facilitates the transport of SNAP-25 containing vesicles as a prerequisite to SNAP-25 driven membrane fusion events.

  13. Amplitude and Ascoli analysis

    International Nuclear Information System (INIS)

    Hansen, J.D.

    1976-01-01

    This article discusses the partial wave analysis of two, three and four meson systems. The difference between the two approaches, referred to as amplitude and Ascoli analysis is discussed. Some of the results obtained with these methods are shown. (B.R.H.)

  14. Reinforcing Saccadic Amplitude Variability

    Science.gov (United States)

    Paeye, Celine; Madelain, Laurent

    2011-01-01

    Saccadic endpoint variability is often viewed as the outcome of neural noise occurring during sensorimotor processing. However, part of this variability might result from operant learning. We tested this hypothesis by reinforcing dispersions of saccadic amplitude distributions, while maintaining constant their medians. In a first experiment we…

  15. Wide-field surveys from the SNAP mission

    International Nuclear Information System (INIS)

    2002-01-01

    The Supernova/Acceleration Probe (SNAP) is a proposed space-borne observatory that will survey the sky with a wide-field optical/NIR imager. The images produced by SNAP will have an unprecedented combination of depth, solid-angle, angular resolution, and temporal sampling. Two 7.5 square-degree fields will be observed every four days over 16 months to a magnitude depth of AB = 27.7 in each of nine filters. Co-adding images over all epochs will give an AB = 30.3 per filter. A 300 square-degree field will be surveyed with no repeat visits to AB = 28 per filter. The nine filters span 3500-17000 (angstrom). Although the survey strategy is tailored for supernova and weak gravitational lensing observations, the resulting data supports a broad range of auxiliary science programs

  16. The destructive effect of botulinum neurotoxins on the SNARE protein: SNAP-25 and synaptic membrane fusion

    Directory of Open Access Journals (Sweden)

    Bin Lu

    2015-06-01

    Full Text Available Synaptic exocytosis requires the assembly of syntaxin 1A and SNAP-25 on the plasma membrane and synaptobrevin 2 (VAMP2 on the vesicular membrane to bridge the two opposite membranes. It is believed that the three SNARE proteins assemble in steps along the dynamic assembly pathway. The C-terminus of SNAP-25 is known to be the target of botulinum neurotoxins (BoNT/A and BoNT/E that block neurotransmitters release in vivo. In this study, we employed electron paramagnetic resonance (EPR spectroscopy to investigate the conformation of the SNAP-25 C-terminus in binary and ternary SNARE complexes. The fluorescence lipid mixing assay shows that the C-terminal of SNAP-25 is essential for membrane fusion, and that the truncated SNAP-25 mutants cleaved by BoNT/A and BoNT/E display different inhibition effects on membrane fusion: SNAP-25E (Δ26 abolishes the fusion activity of the SNARE complex, while SNAP-25A (Δ9 loses most of its function, although it can still form a SDS-resistant SNARE complex as the wild-type SNAP-25. CW-EPR spectra validate the unstable structures of the SNARE complex formed by SNAP-25 mutants. We propose that the truncated SNAP-25 mutants will disrupt the assembly of the SNARE core complex, and then inhibit the synaptic membrane fusion accordingly.

  17. Snapping shrimp sound production patterns on Caribbean coral reefs: relationships with celestial cycles and environmental variables

    Science.gov (United States)

    Lillis, Ashlee; Mooney, T. Aran

    2018-06-01

    The rich acoustic environment of coral reefs, including the sounds of a variety of fish and invertebrates, is a reflection of the structural complexity and biological diversity of these habitats. Emerging interest in applying passive acoustic monitoring and soundscape analysis to measure coral reef habitat characteristics and track ecological patterns is hindered by a poor understanding of the most common and abundant sound producers on reefs—the snapping shrimp. Here, we sought to address several basic biophysical drivers of reef sound by investigating acoustic activity patterns of snapping shrimp populations on two adjacent coral reefs using a detailed snap detection analysis routine to a high-resolution 2.5-month acoustic dataset from the US Virgin Islands. The reefs exhibited strong diel and lunar periodicity in snap rates and clear spatial differences in snapping levels. Snap rates peaked at dawn and dusk and were higher overall during daytime versus nighttime, a seldom-reported pattern in earlier descriptions of diel snapping shrimp acoustic activity. Small differences between the sites in snap rate rhythms were detected and illustrate how analyses of specific soundscape elements might reveal subtle between-reef variation. Snap rates were highly correlated with environmental variables, including water temperature and light, and were found to be sensitive to changes in oceanographic forcing. This study further establishes snapping shrimp as key players in the coral reef chorus and provides evidence that their acoustic output reflects a combination of environmental conditions, celestial influences, and spatial habitat variation. Effective application of passive acoustic monitoring in coral reef habitats using snap rates or snapping-influenced acoustic metrics will require a mechanistic understanding of the underlying spatial and temporal variation in snapping shrimp sound production across multiple scales.

  18. SnapShot: Hormones of the gastrointestinal tract.

    Science.gov (United States)

    Coate, Katie C; Kliewer, Steven A; Mangelsdorf, David J

    2014-12-04

    Specialized endocrine cells secrete a variety of peptide hormones all along the gastrointestinal (GI) tract, making it one of the largest endocrine organs in the body. Nutrients and developmental and neural cues trigger the secretion of gastrointestinal (GI) hormones from specialized endocrine cells along the GI tract. These hormones act in target tissues to facilitate digestion and regulate energy homeostasis. This SnapShot summarizes the production and functions of GI hormones. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. SnapShot: Fanconi anemia and associated proteins.

    Science.gov (United States)

    Wang, Anderson T; Smogorzewska, Agata

    2015-01-15

    Fanconi anemia is a genetic disorder resulting from biallelic mutations in one of the 17 FANC genes. It is characterized by congenital abnormalities, bone marrow failure, and cancer predisposition. The underlying cause is genomic instability resulting from the deficiency in replication-dependent DNA interstrand crosslink repair pathway commonly referred to as the Fanconi anemia-BRCA pathway. This SnapShot presents the key factors involved. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Preparing diagnostic data for the SNAP transport code

    International Nuclear Information System (INIS)

    Murphy, J.A.; Scott, S.D.; Towner, H.H.

    1992-01-01

    This paper describes the program SNAPIN which is used to prepare data for transport analysis with the SNAP code. The data input to SNAP includes diagnostic profiles [n e (R), T e (R), T i (R), v φ (R), Z eff (R), P rad (R)] and measurements such as total plasma current, R major , beam power, gas puff rate, etc. SNAPIN reads in the necessary TFTR data, allows editing of that data, including graphical editing of profile data and the selection of physics models. SNAPIN allows comparison of profile data from all diagnostics that measure a quantity, for example, electron temperature profiles from Thomson scattering and electron cyclotron emission (ECE). A powerful user interface is important to help the user prepare input data sets quickly and consistently, because hundreds of variables must be specified for each analysis. SNAPIN facilitates this by a careful organization of menus, display of all scalar data and switch settings within the menus, the graphical editing and comparison of profiles, and step-by-step checking for consistent physics controls [J. Murphy, S. Scott, and H. Towner, The SNAP User's Guide, Technical Report PPPL-TM-393, Princeton Plasma Physics Laboratory (1992)

  1. Molecular Investigation of the Stem Snap Point in Textile Hemp

    Directory of Open Access Journals (Sweden)

    Marc Behr

    2017-12-01

    Full Text Available Fibre crops are important natural resources, as they sustainably provide bast fibres, an economically-valuable raw material used in the textile and biocomposite sectors. Among fibre crops, textile hemp (Cannabis sativa L. is appreciated for its long and strong gelatinous bast fibres. The stem of fibre crops is a useful system for cell wall-oriented studies, because it shows a strong tissue polarity with a lignified inner core and a cellulosic hypolignified cortex, as well as a basipetal lignification gradient. Along the stem axis of fibre crops, a specific region, denoted snap point, marks the transition from elongation (above it to fibre thickening (below it. After empirically determining the snap point by tilting the plant, we divided the stem segment containing it into three non-overlapping consecutive regions measuring 1 cm each, and carried out targeted RT-qPCR on cell wall-related genes separately, in outer and inner tissues. Different gene clusters can be observed, two of which are the major gene groups, i.e., one group with members expressed at higher levels in the inner tissues, and one group whose genes are more expressed in the cortex. The present results provide a molecular validation that the snap point is characterised by a gradient of events associated with the shift from fibre elongation to thickening.

  2. Light Meson Distribution Amplitudes

    CERN Document Server

    Arthur, R.; Brommel, D.; Donnellan, M.A.; Flynn, J.M.; Juttner, A.; de Lima, H.Pedroso; Rae, T.D.; Sachrajda, C.T.; Samways, B.

    2010-01-01

    We calculated the first two moments of the light-cone distribution amplitudes for the pseudoscalar mesons ($\\pi$ and $K$) and the longitudinally polarised vector mesons ($\\rho$, $K^*$ and $\\phi$) as part of the UKQCD and RBC collaborations' $N_f=2+1$ domain-wall fermion phenomenology programme. These quantities were obtained with a good precision and, in particular, the expected effects of $SU(3)$-flavour symmetry breaking were observed. Operators were renormalised non-perturbatively and extrapolations to the physical point were made, guided by leading order chiral perturbation theory. The main results presented are for two volumes, $16^3\\times 32$ and $24^3\\times 64$, with a common lattice spacing. Preliminary results for a lattice with a finer lattice spacing, $32^3\\times64$, are discussed and a first look is taken at the use of twisted boundary conditions to extract distribution amplitudes.

  3. Defining SNAP by cross-sectional and longitudinal definitions of neurodegeneration

    OpenAIRE

    Wisse, L.E.M.; Das, S.R.; Davatzikos, C.; Dickerson, B.C.; Xie, S.X.; Yushkevich, P.A.; Wolk, D.A.

    2018-01-01

    Introduction: Suspected non-Alzheimer's pathophysiology (SNAP) is a biomarker driven designation that represents a heterogeneous group in terms of etiology and prognosis. SNAP has only been identified by cross-sectional neurodegeneration measures, whereas longitudinal measures might better reflect “active” neurodegeneration and might be more tightly linked to prognosis. We compare neurodegeneration defined by cross-sectional ‘hippocampal volume’ only (SNAP/L−) versus both cross-sectional and ...

  4. Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering

    DEFF Research Database (Denmark)

    Mohrmann, Ralf; de Wit, Heidi; Connell, Emma

    2013-01-01

    ramifications of proposed SNAP-25 × synaptotagmin-1 interaction in mouse chromaffin cells. We demonstrate that the postulated central binding domain surrounding layer zero covers both SNARE motifs of SNAP-25 and is essential for vesicle docking, priming, and fast fusion-triggering. Mutation of this site caused...... but is required for the full size of the readily releasable pool. Intriguingly, we also found that mutation of synaptotagmin-1 interaction sites led to more pronounced phenotypes in the context of the adult neuronal isoform SNAP-25B than in the embryonic isoform SNAP-25A. Further experiments demonstrated...

  5. Efficient radiological assessment of the internal snapping hip syndrome

    International Nuclear Information System (INIS)

    Wunderbaldinger, P.; Bremer, C.; Matuszewski, L.; Marten, K.; Turetschek, K.; Rand, T.

    2001-01-01

    The aim of this study was to evaluate the diagnostic value/significance of various imaging techniques for demonstrating the underlying causative pathology of clinically suspected internal snapping hip syndrome. We intended to define the most efficient diagnostic imaging algorithm that leads to a specific definite therapy for this rare hip disorder. The imaging studies of 54 patients (43 women, 11 men, average age 58 years) with the clinical suspicion of internal snapping hip syndrome were compared for their diagnostic value/significance for finding the underlying pathology. Radiological workup included plain radiographs of the pelvis and hip joints (n=54), ultrasound (US) of the hip joints (n=29), computed tomography (CT) of the pelvis and proximal femur (n=17), and magnetic resonance imaging (MRI) of the pelvis/hip joint (n=21). In order to establish an efficient diagnostic algorithm we compared the diagnostic value of each imaging technique alone and in combination with the other methods. The underlying causative pathology could be established in 37% of patients (n=20) by the use of conventional radiographs alone and in 46% of the patients (n=25) by US alone, and in combination in 83% of the patients (n=45). By adding CT to the radiological workup, we established final diagnosis in 88% (in combination with X-ray; n=15/17) and 94% (together with X-ray and US; n=16/17) of the patients. Whenever MR imaging was used a causative pathology was found in all patients (100%; n=21). The most efficient radiological algorithm in the assessment of patients with internal snapping hip syndrome is the combination of plain radiography and US. MR imaging can be retained for unresolved and difficult cases. (orig.)

  6. SNAP 19 Pioneer F and G. Final Report

    Science.gov (United States)

    1973-06-01

    The generator developed for the Pioneer mission evolved from the SNAP 19 RTG`s launched aboard the NIMBUS III spacecraft. In order to satisfy the power requirements and environment of earth escape trajectory, significant modifications were made to the thermoelectric converter, heat source, and structural configuration. Specifically, a TAGS 2N thermoelectric couple was designed to provide higher efficiency and improved long term power performance, and the electrical circuitry was modified to yield very low magnetic field from current flow in the RTG. A new heat source was employed to satisfy operational requirements and its integration with the generator required alteration to the method of providing support to the fuel capsule.

  7. Snaps to Connect Coaxial and Microstrip Lines in Wearable Systems

    Directory of Open Access Journals (Sweden)

    Tiiti Kellomäki

    2012-01-01

    Full Text Available Commercial snaps (clothing fasteners can be used to connect a coaxial cable to a microstrip line. This is useful in the context of wearable antennas, especially in consumer applications and disposable connections. The measured S-parameters of the transition are presented, and an equivalent circuit and approximate equations are derived for system design purposes. The proposed connection is usable up to 1.5 GHz (10 dB return loss condition, and the frequency range can be extended to 2 GHz if a thinner, more flexible coaxial cable is used.

  8. Lipid droplets interact with mitochondria using SNAP23

    DEFF Research Database (Denmark)

    Jägerström, Sara; Polesie, Sam; Wickström, Ylva

    2009-01-01

    peroxisomes and the endoplasmic reticulum. We have used electron and confocal microscopy to demonstrate that LD form complexes with mitochondria in NIH 3T3 fibroblasts. Using an in vitro system of purified LD and mitochondria, we also show the formation of the LD-mitochondria complex, in which cytosolic...... factors are involved. Moreover, the presence of LD markers in mitochondria isolated by subcellular fractionations is demonstrated. Finally, ablation of SNAP23 using siRNA reduced complex formation and beta oxidation, which suggests that the LD-mitochondria complex is functional in the cell....

  9. SNAP-25 in hippocampal CA3 region is required for long-term memory formation

    International Nuclear Information System (INIS)

    Hou Qiuling; Gao Xiang; Lu Qi; Zhang Xuehan; Tu Yanyang; Jin Meilei; Zhao Guoping; Yu Lei; Jing Naihe; Li Baoming

    2006-01-01

    SNAP-25 is a synaptosomal protein of 25 kDa, a key component of synaptic vesicle-docking/fusion machinery, and plays a critical role in exocytosis and neurotransmitter release. We previously reported that SNAP-25 in the hippocampal CA1 region is involved in consolidation of contextual fear memory and water-maze spatial memory (Hou et al. European J Neuroscience, 20: 1593-1603, 2004). SNAP-25 is expressed not only in the CA1 region, but also in the CA3 region, and the SNAP-25 mRNA level in the CA3 region is higher than in the CA1 region. Here, we provide evidence that SNAP-25 in the CA3 region is also involved in learning/memory. Intra-CA3 infusion of SNAP-25 antisense oligonucleotide impaired both long-term contextual fear memory and water-maze spatial memory, with short-term memory intact. Furthermore, the SNAP-25 antisense oligonucleotide suppressed the long-term potentiation (LTP) of field excitatory post-synaptic potential (fEPSP) in the mossy-fiber pathway (DG-CA3 pathway), with no effect on paired-pulse facilitation of the fEPSP. These results are consistent with the notion that SNAP-25 in the hippocampal CA3 region is required for long-term memory formation

  10. Effect of temporary drought at different growth stages on snap bean ...

    African Journals Online (AJOL)

    High quality snap bean (Phaseolus vulgaris L.) can be produced under rain-fed conditions, provided that adequate moisture is available. However, drought may occur at any stage of growth of snap bean. The objective of this study was to evaluate the effect of drought stress at different growth stages on pod physical quality ...

  11. 78 FR 12245 - Supplemental Nutrition Assistance Program: Suspension of SNAP Benefit Payments to Retailers

    Science.gov (United States)

    2013-02-22

    ..., national origin, gender, age, disability, marital or family status. Regulations at 7 CFR 272.6.... Discrimination in any aspect of the program administration is prohibited by these regulations, according to the... SNAP benefits at the location, store inventory, and the SNAP history of the store owners. For example...

  12. Geometrically controlled snapping transitions in shells with curved creases.

    Science.gov (United States)

    Bende, Nakul Prabhakar; Evans, Arthur A; Innes-Gold, Sarah; Marin, Luis A; Cohen, Itai; Hayward, Ryan C; Santangelo, Christian D

    2015-09-08

    Curvature and mechanics are intimately connected for thin materials, and this coupling between geometry and physical properties is readily seen in folded structures from intestinal villi and pollen grains to wrinkled membranes and programmable metamaterials. While the well-known rules and mechanisms behind folding a flat surface have been used to create deployable structures and shape transformable materials, folding of curved shells is still not fundamentally understood. Shells naturally deform by simultaneously bending and stretching, and while this coupling gives them great stability for engineering applications, it makes folding a surface of arbitrary curvature a nontrivial task. Here we discuss the geometry of folding a creased shell, and demonstrate theoretically the conditions under which it may fold smoothly. When these conditions are violated we show, using experiments and simulations, that shells undergo rapid snapping motion to fold from one stable configuration to another. Although material asymmetry is a proven mechanism for creating this bifurcation of stability, for the case of a creased shell, the inherent geometry itself serves as a barrier to folding. We discuss here how two fundamental geometric concepts, creases and curvature, combine to allow rapid transitions from one stable state to another. Independent of material system and length scale, the design rule that we introduce here explains how to generate snapping transitions in arbitrary surfaces, thus facilitating the creation of programmable multistable materials with fast actuation capabilities.

  13. Critical homoclinic orbits lead to snap-back repellers

    International Nuclear Information System (INIS)

    Gardini, Laura; Sushko, Iryna; Avrutin, Viktor; Schanz, Michael

    2011-01-01

    Highlights: → We consider critical homoclinic orbits in continuous and discontinuous maps. → Unbounded homoclinic orbits in maps on unbounded domains are considered as well. → We show that a snapback-repeller (SBR) with a non-critical homoclinic orbit implies chaos. → We show also that a SBR with a critical homoclinic orbit may or may not imply chaos. - Abstract: When nondegenerate homoclinic orbits to an expanding fixed point of a map f:X→X,X subset or equal R n , exist, the point is called a snap-back repeller. It is known that the relevance of a snap-back repeller (in its original definition) is due to the fact that it implies the existence of an invariant set on which the map is chaotic. However, when does the first homoclinic orbit appear? When can other homoclinic explosions, i.e., appearance of infinitely many new homoclinic orbits, occur? As noticed by many authors, these problems are still open. In this work we characterize these bifurcations, for any kind of map, smooth or piecewise smooth, continuous or discontinuous, defined in a bounded or unbounded closed set. We define a noncritical homoclinic orbit and a homoclinic orbit of an expanding fixed point is structurally stable iff it is noncritical. That is, only critical homoclinic orbits are responsible for the homoclinic explosions. The possible kinds of critical homoclinic orbits will be also investigated, as well as their dynamic role.

  14. Magnetoelastic bending and snapping of ferromagnetic plates in oblique magnetic fields

    International Nuclear Information System (INIS)

    Zhou Youhe

    1995-01-01

    Ferritic stainless steel has been considered for structural components such as first walls and blankets of fusion power reactors because the material shows low rates of irradiation swelling. Since it is magnetizable, the magnetoelastic interaction between magnetic field and deformation of the structures in a fusion reactor is so strong that their safety is of concern due to the magnetoelastic bending, buckling and magnetic damping, etc. Basic research of the magnetoelastic characteristics of ferromagnetic plate has been paid special attention by researchers. In this paper, the magnetoelastic bending and snapping are studied for a ferromagnetic plate in an oblique magnetic field. The theoretical model is based on the variational principle where the functional is employed as real total energy in the system including external work. The obtained expression of magnetic force on the plate is the same as that derived from the dipole model when the total magnetic field in the ferromagnetic medium is considered. In order to effectively solve the nonlinearly coupled interaction problem between magnetic field and mechanical deformation, a numerical program combining the finite element method for analyzing the magnetic field with the finite difference technique for finding out the bending deformation of the plate is employed to obtain the solution of magnetoelastic bending of a soft ferromagnetic plate. The numerical calculations are carried out for the typical example of a ferromagnetic cantilevered beam-plate in an oblique magnetic field. From the bending curves, that is the tip deflection versus applied magnetic fields, the critical magnetic field for the magnetoelastic snapping is predicted by the Southwell plot. The theoretical predictions show that the critical magnetic field decreases with the increase in incident angle of the oblique magnetic field. By the effect of incident angle on the magnetic buckling, the discrepancy between theoretical and experimental data can

  15. Defining SNAP by cross-sectional and longitudinal definitions of neurodegeneration.

    Science.gov (United States)

    Wisse, L E M; Das, S R; Davatzikos, C; Dickerson, B C; Xie, S X; Yushkevich, P A; Wolk, D A

    2018-01-01

    Suspected non-Alzheimer's pathophysiology (SNAP) is a biomarker driven designation that represents a heterogeneous group in terms of etiology and prognosis. SNAP has only been identified by cross-sectional neurodegeneration measures, whereas longitudinal measures might better reflect "active" neurodegeneration and might be more tightly linked to prognosis. We compare neurodegeneration defined by cross-sectional 'hippocampal volume' only (SNAP/L-) versus both cross-sectional and longitudinal 'hippocampal atrophy rate' (SNAP/L+) and investigate how these definitions impact prevalence and the clinical and biomarker profile of SNAP in Mild Cognitive Impairment (MCI). 276 MCI patients from ADNI-GO/2 were designated amyloid "positive" (A+) or "negative" (A-) based on their florbetapir scan and neurodegeneration 'positive' or 'negative' based on cross-sectional hippocampal volume and longitudinal hippocampal atrophy rate. 74.1% of all SNAP participants defined by the cross-sectional definition of neurodegeneration also met the longitudinal definition of neurodegeneration, whereas 25.9% did not. SNAP/L+ displayed larger white matter hyperintensity volume, a higher conversion rate to dementia over 5 years and a steeper decline on cognitive tasks compared to SNAP/L- and the A- CN group. SNAP/L- had more abnormal values on neuroimaging markers and worse performance on cognitive tasks than the A- CN group, but did not show a difference in dementia conversion rate or longitudinal cognition. Using a longitudinal definition of neurodegeneration in addition to a cross-sectional one identifies SNAP participants with significant cognitive decline and a worse clinical prognosis for which cerebrovascular disease may be an important driver.

  16. Telling our stories: heroin-assisted treatment and SNAP activism in the Downtown Eastside of Vancouver.

    Science.gov (United States)

    Boyd, Susan; Murray, Dave; MacPherson, Donald

    2017-05-18

    This article highlights the experiences of a peer-run group, SALOME/NAOMI Association of Patients (SNAP), that meets weekly in the Downtown Eastside of Vancouver, British Columbia, Canada. SNAP is a unique independent peer- run drug user group that formed in 2011 following Canada's first heroin-assisted treatment trial (HAT), North America Opiate Medication Initiative (NAOMI). SNAP's members are now made up of former research participants who participated in two heroin-assisted trials in Vancouver. This article highlights SNAP members' experiences as research subjects in Canada's second clinical trial conducted in Vancouver, Study to Assess Longer-term Opioid Medication Effectiveness (SALOME), that began recruitment of research participants in 2011. This paper draws on one brainstorming session, three focus groups, and field notes, with the SALOME/NAOMI Association of Patients (SNAP) in late 2013 about their experiences as research subjects in Canada's second clinical trial, SALOME in the DTES of Vancouver, and fieldwork from a 6-year period (March 2011 to February 2017) with SNAP members. SNAP's research draws on research principles developed by drug user groups and critical methodological frameworks on community-based research for social justice. The results illuminate how participating in the SALOME clinical trial impacted the lives of SNAP members. In addition, the findings reveal how SNAP member's advocacy for HAT impacts the group in positive ways. Seven major themes emerged from the analysis of the brainstorming and focus groups: life prior to SALOME, the clinic setting and routine, stability, 6-month transition, support, exiting the trial and ethics, and collective action, including their participation in a constitutional challenge in the Supreme Court of BC to continue receiving HAT once the SALOME trial ended. HAT benefits SNAP members. They argue that permanent HAT programs should be established in Canada because they are an effective harm reduction

  17. Unifying relations for scattering amplitudes

    Science.gov (United States)

    Cheung, Clifford; Shen, Chia-Hsien; Wen, Congkao

    2018-02-01

    We derive new amplitudes relations revealing a hidden unity among a wideranging variety of theories in arbitrary spacetime dimensions. Our results rely on a set of Lorentz invariant differential operators which transmute physical tree-level scattering amplitudes into new ones. By transmuting the amplitudes of gravity coupled to a dilaton and two-form, we generate all the amplitudes of Einstein-Yang-Mills theory, Dirac-Born-Infield theory, special Galileon, nonlinear sigma model, and biadjoint scalar theory. Transmutation also relates amplitudes in string theory and its variants. As a corollary, celebrated aspects of gluon and graviton scattering like color-kinematics duality, the KLT relations, and the CHY construction are inherited traits of the transmuted amplitudes. Transmutation recasts the Adler zero as a trivial consequence of the Weinberg soft theorem and implies new subleading soft theorems for certain scalar theories.

  18. Hidden beauty in multiloop amplitudes

    International Nuclear Information System (INIS)

    Cachazo, Freddy; Spradlin, Marcus; Volovich, Anastasia

    2006-01-01

    Planar L-loop maximally helicity violating amplitudes in N = 4 supersymmetric Yang-Mills theory are believed to possess the remarkable property of satisfying iteration relations in L. We propose a simple new method for studying iteration relations for four-particle amplitudes which involves the use of certain linear differential operators and eliminates the need to fully evaluate any loop integrals. We carry out this procedure in explicit detail for the two-loop amplitude and prove that this method can be applied to any multiloop integral, allowing a conjectured iteration relation for any given amplitude to be tested up to polynomials in logarithms

  19. Two-Loop Splitting Amplitudes

    International Nuclear Information System (INIS)

    Bern, Z.

    2004-01-01

    Splitting amplitudes govern the behavior of scattering amplitudes at the momenta of external legs become collinear. In this talk we outline the calculation of two-loop splitting amplitudes via the unitarity sewing method. This method retains the simple factorization properties of light-cone gauge, but avoids the need for prescriptions such as the principal value or Mandelstam-Leibbrandt ones. The encountered loop momentum integrals are then evaluated using integration-by-parts and Lorentz invariance identities. We outline a variety of applications for these splitting amplitudes

  20. Two-loop splitting amplitudes

    International Nuclear Information System (INIS)

    Bern, Z.; Dixon, L.J.; Kosower, D.A.

    2004-01-01

    Splitting amplitudes govern the behavior of scattering amplitudes at the momenta of external legs become collinear. In this talk we outline the calculation of two-loop splitting amplitudes via the unitarity sewing method. This method retains the simple factorization properties of light-cone gauge, but avoids the need for prescriptions such as the principal value or Mandelstam-Leibbrandt ones. The encountered loop momentum integrals are then evaluated using integration-by-parts and Lorentz invariance identities. We outline a variety of applications for these splitting amplitudes

  1. An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function.

    Directory of Open Access Journals (Sweden)

    Jenny U Johansson

    2008-11-01

    Full Text Available Alternative splicing is an evolutionary innovation to create functionally diverse proteins from a limited number of genes. SNAP-25 plays a central role in neuroexocytosis by bridging synaptic vesicles to the plasma membrane during regulated exocytosis. The SNAP-25 polypeptide is encoded by a single copy gene, but in higher vertebrates a duplication of exon 5 has resulted in two mutually exclusive splice variants, SNAP-25a and SNAP-25b. To address a potential physiological difference between the two SNAP-25 proteins, we generated gene targeted SNAP-25b deficient mouse mutants by replacing the SNAP-25b specific exon with a second SNAP-25a equivalent. Elimination of SNAP-25b expression resulted in developmental defects, spontaneous seizures, and impaired short-term synaptic plasticity. In adult mutants, morphological changes in hippocampus and drastically altered neuropeptide expression were accompanied by severe impairment of spatial learning. We conclude that the ancient exon duplication in the Snap25 gene provides additional SNAP-25-function required for complex neuronal processes in higher eukaryotes.

  2. Modulation of long-latency afferent inhibition by the amplitude of sensory afferent volley.

    Science.gov (United States)

    Turco, Claudia V; El-Sayes, Jenin; Fassett, Hunter J; Chen, Robert; Nelson, Aimee J

    2017-07-01

    Long-latency afferent inhibition (LAI) is the inhibition of the transcranial magnetic stimulation (TMS) motor-evoked potentials (MEP) by the sensory afferent volley following electrical stimulation of a peripheral nerve. It is unknown how the activation of sensory afferent fibers relates to the magnitude of LAI. This study investigated the relationship between LAI and the sensory nerve action potentials (SNAP) from the median nerve (MN) and the digital nerves (DN) of the second digit. LAI was obtained by delivering nerve stimulation 200 ms before a TMS pulse delivered over the motor cortex. Experiment 1 assessed the magnitude of LAI following stimulation of the contralateral MN or DN using nerve stimulus intensities relative to the maximum SNAP (SNAP max ) of that nerve and two TMS intensities (0.5- and 1-mV MEP). Results indicate that MN LAI is maximal at ~50% SNAP max , when presumably all sensory afferents are recruited for TMS of 0.5-mV MEP. For DN, LAI appears at ~50% SNAP max and does not increase with further recruitment of sensory afferents. Experiment 2 investigated the magnitude of LAI following ipsilateral nerve stimulation at intensities relative to SNAP max Results show minimal LAI evoked by ipsilateral MN and no LAI following ipsilateral DN stimulation. Implications for future studies investigating LAI include adjusting nerve stimulation to 50% SNAP max to obtain maximal LAI. Additionally, MN LAI can be used as a marker for neurological disease or injury by using a nerve stimulation intensity that can evoke a depth of LAI capable of increasing or decreasing. NEW & NOTEWORTHY This is the first investigation of the relationship between long-latency afferent inhibition (LAI) and the sensory afferent volley. Differences exist between median and digital nerve LAI. For the median nerve, LAI increases until all sensory fibers are presumably recruited. In contrast, digital nerve LAI does not increase with the recruitment of additional sensory fibers but

  3. An oscillating wave energy converter with nonlinear snap-through Power-Take-Off systems in regular waves

    Science.gov (United States)

    Zhang, Xian-tao; Yang, Jian-min; Xiao, Long-fei

    2016-07-01

    Floating oscillating bodies constitute a large class of wave energy converters, especially for offshore deployment. Usually the Power-Take-Off (PTO) system is a directly linear electric generator or a hydraulic motor that drives an electric generator. The PTO system is simplified as a linear spring and a linear damper. However the conversion is less powerful with wave periods off resonance. Thus, a nonlinear snap-through mechanism with two symmetrically oblique springs and a linear damper is applied in the PTO system. The nonlinear snap-through mechanism is characteristics of negative stiffness and double-well potential. An important nonlinear parameter γ is defined as the ratio of half of the horizontal distance between the two springs to the original length of both springs. Time domain method is applied to the dynamics of wave energy converter in regular waves. And the state space model is used to replace the convolution terms in the time domain equation. The results show that the energy harvested by the nonlinear PTO system is larger than that by linear system for low frequency input. While the power captured by nonlinear converters is slightly smaller than that by linear converters for high frequency input. The wave amplitude, damping coefficient of PTO systems and the nonlinear parameter γ affect power capture performance of nonlinear converters. The oscillation of nonlinear wave energy converters may be local or periodically inter well for certain values of the incident wave frequency and the nonlinear parameter γ, which is different from linear converters characteristics of sinusoidal response in regular waves.

  4. Effect of dry mycelium of Penicillium chrysogenum fertilizer on soil microbial community composition, enzyme activities and snap bean growth.

    Science.gov (United States)

    Wang, Bing; Liu, Huiling; Cai, Chen; Thabit, Mohamed; Wang, Pu; Li, Guomin; Duan, Ziheng

    2016-10-01

    The dry mycelium fertilizer (DMF) was produced from penicillin fermentation fungi mycelium (PFFM) following an acid-heating pretreatment to degrade the residual penicillin. In this study, it was applied into soil as fertilizer to investigate its effects on soil properties, phytotoxicity, microbial community composition, enzyme activities, and growth of snap bean in greenhouse. As the results show, pH, total nitrogen, total phosphorus, total potassium, and organic matter of soil with DMF treatments were generally higher than CON treatment. In addition, the applied DMF did not cause heavy metal and residual drug pollution of the modified soil. The lowest GI values (<0.3) were recorded at DMF8 (36 kg DMF/plat) on the first days after applying the fertilizer, indicating that severe phytotoxicity appeared in the DMF8-modified soil. Results of microbial population and enzyme activities illustrated that DMF was rapidly decomposed and the decomposition process significantly affected microbial growth and enzyme activities. The DMF-modified soil phytotoxicity decreased at the late fertilization time. DMF1 was considered as the optimum amount of DMF dose based on principal component analysis scores. Plant height and plant yield of snap bean were remarkably enhanced with the optimum DMF dose.

  5. Polycyclic aromatic hydrocarbons affect survival and development of common snapping turtle (Chelydra serpentina) embryos and hatchlings

    Energy Technology Data Exchange (ETDEWEB)

    Van Meter, Robin J [School of Environmental Science, Engineering, and Policy and Department of Bioscience and Biotechnology, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104 (United States); Spotila, James R [School of Environmental Science, Engineering, and Policy and Department of Bioscience and Biotechnology, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104 (United States); Avery, Harold W [School of Environmental Science, Engineering, and Policy and Department of Bioscience and Biotechnology, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104 (United States)

    2006-08-15

    Polycyclic aromatic hydrocarbons (PAHs) are toxic compounds found in the John Heinz National Wildlife Refuge in Philadelphia, Pennsylvania. We assessed the impact of PAHs and crude oil on snapping turtle development and behavior by exposing snapping turtle eggs from the Refuge and from three clean reference sites to individual PAHs or a crude oil mixture at stage 9 of embryonic development. Exposure to PAHs had a significant effect on survival rates in embryos from one clean reference site, but not in embryos from the other sites. There was a positive linear relationship between level of exposure to PAHs and severity of deformities in embryos collected from two of the clean reference sites. Neither righting response nor upper temperature tolerance (critical thermal maximum, CTM) of snapping turtle hatchlings with no or minor deformities was significantly affected by exposure to PAHs. - Exposure to polycyclic aromatic hydrocarbons on the egg reduces survival of snapping turtle embryos and causes developmental abnormalities.

  6. Polycyclic aromatic hydrocarbons affect survival and development of common snapping turtle (Chelydra serpentina) embryos and hatchlings

    International Nuclear Information System (INIS)

    Van Meter, Robin J.; Spotila, James R.; Avery, Harold W.

    2006-01-01

    Polycyclic aromatic hydrocarbons (PAHs) are toxic compounds found in the John Heinz National Wildlife Refuge in Philadelphia, Pennsylvania. We assessed the impact of PAHs and crude oil on snapping turtle development and behavior by exposing snapping turtle eggs from the Refuge and from three clean reference sites to individual PAHs or a crude oil mixture at stage 9 of embryonic development. Exposure to PAHs had a significant effect on survival rates in embryos from one clean reference site, but not in embryos from the other sites. There was a positive linear relationship between level of exposure to PAHs and severity of deformities in embryos collected from two of the clean reference sites. Neither righting response nor upper temperature tolerance (critical thermal maximum, CTM) of snapping turtle hatchlings with no or minor deformities was significantly affected by exposure to PAHs. - Exposure to polycyclic aromatic hydrocarbons on the egg reduces survival of snapping turtle embryos and causes developmental abnormalities

  7. Intra-axonal Synthesis of SNAP25 Is Required for the Formation of Presynaptic Terminals

    Directory of Open Access Journals (Sweden)

    Andreia F.R. Batista

    2017-09-01

    Full Text Available Localized protein synthesis is a mechanism for developing axons to react acutely and in a spatially restricted manner to extracellular signals. As such, it is important for many aspects of axonal development, but its role in the formation of presynapses remains poorly understood. We found that the induced assembly of presynaptic terminals required local protein synthesis. Newly synthesized proteins were detectable at nascent presynapses within 15 min of inducing synapse formation in isolated axons. The transcript for the t-SNARE protein SNAP25, which is required for the fusion of synaptic vesicles with the plasma membrane, was recruited to presynaptic sites and locally translated. Inhibition of intra-axonal SNAP25 synthesis affected the clustering of SNAP25 and other presynaptic proteins and interfered with the release of synaptic vesicles from presynaptic sites. This study reveals a critical role for the axonal synthesis of SNAP25 in the assembly of presynaptic terminals.

  8. A meniscus causing painful snapping of the elbow joint: MR imaging with arthroscopic and histologic correlation

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Guo-Shu; Chen, Cheng-Yu [National Defense Medical Center, Department of Radiology, Tri-Service General Hospital, Taipei (Taiwan); Lee, Chian-Her [National Defense Medical Center, Department of Orthopedic Surgery, Tri-Service General Hospital, Taipei (Taiwan); Lee, Herng-Sheng [National Defense Medical Center, Department of Pathology, Tri-Service General Hospital, Taipei (Taiwan)

    2005-12-01

    Snapping of the elbow joint can cause pain. We report a case of painful snapping elbow produced by an interposed meniscus in the radiohumeral joint in a 20-year-old man. The MR arthrogram demonstrated a meniscus-like tissue interposed between the radial head and humeral capitellum. The MR-arthrographic findings were well correlated with surgical findings. The location and appearance of the meniscus-like tissue was similar to that of meniscus in the knee joint. Histologic findings of the excised meniscus-like tissue showed a typical presentation of fibrocartilage. A meniscus may exist in the elbow joint and can be a rare cause of painful snapping elbow. MR arthrography is helpful for identifying the snapping tissue in the elbow joint. (orig.)

  9. α-SNAP prevents docking of the acrosome during sperm exocytosis because it sequesters monomeric syntaxin.

    Directory of Open Access Journals (Sweden)

    Facundo Rodríguez

    Full Text Available α-SNAP has an essential role in membrane fusion that consists of bridging cis SNARE complexes to NSF. α-SNAP stimulates NSF, which releases itself, α-SNAP, and individual SNAREs that subsequently re-engage in the trans arrays indispensable for fusion. α-SNAP also binds monomeric syntaxin and NSF disengages the α-SNAP/syntaxin dimer. Here, we examine why recombinant α-SNAP blocks secretion in permeabilized human sperm despite the fact that the endogenous protein is essential for membrane fusion. The only mammalian organism with a genetically modified α-SNAP is the hyh mouse strain, which bears a M105I point mutation; males are subfertile due to defective sperm exocytosis. We report here that recombinant α-SNAP-M105I has greater affinity for the cytosolic portion of immunoprecipitated syntaxin than the wild type protein and in consequence NSF is less efficient in releasing the mutant. α-SNAP-M105I is a more potent sperm exocytosis blocker than the wild type and requires higher concentrations of NSF to rescue its effect. Unlike other fusion scenarios where SNAREs are subjected to an assembly/disassembly cycle, the fusion machinery in sperm is tuned so that SNAREs progress uni-directionally from a cis configuration in resting cells to monomeric and subsequently trans arrays in cells challenged with exocytosis inducers. By means of functional and indirect immunofluorescense assays, we show that recombinant α-SNAPs--wild type and M105I--inhibit exocytosis because they bind monomeric syntaxin and prevent this SNARE from assembling with its cognates in trans. Sequestration of free syntaxin impedes docking of the acrosome to the plasma membrane assessed by transmission electron microscopy. The N-terminal deletion mutant α-SNAP-(160-295, unable to bind syntaxin, affects neither docking nor secretion. The implications of this study are twofold: our findings explain the fertility defect of hyh mice and indicate that assembly of SNAREs in trans

  10. Off-shell CHY amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Lam, C.S., E-mail: Lam@physics.mcgill.ca [Department of Physics, McGill University, Montreal, Q.C., H3A 2T8 (Canada); Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, V6T 1Z1 (Canada); Yao, York-Peng, E-mail: yyao@umich.edu [Department of Physics, The University of Michigan Ann Arbor, MI 48109 (United States)

    2016-06-15

    The Cachazo–He–Yuan (CHY) formula for on-shell scattering amplitudes is extended off-shell. The off-shell amplitudes (amputated Green's functions) are Möbius invariant, and have the same momentum poles as the on-shell amplitudes. The working principles which drive the modifications to the scattering equations are mainly Möbius covariance and energy momentum conservation in off-shell kinematics. The same technique is also used to obtain off-shell massive scalars. A simple off-shell extension of the CHY gauge formula which is Möbius invariant is proposed, but its true nature awaits further study.

  11. Measuring the Effect of Supplemental Nutrition Assistance Program (SNAP) Participation on Food Security.

    OpenAIRE

    James Mabli; Jim Ohls; Lisa Dragoset; Laura Castner; Betsy Santos

    2013-01-01

    The Supplemental Nutrition Assistance Program (SNAP) provides food assistance to more than 47 million low-income Americans every month. It aims to reduce hunger by facilitating beneficiaries’ access to enough food for a healthy, active lifestyle, otherwise known as "food security." Our study conducted for the Food and Nutrition Service of the U.S. Department of Agriculture shows that SNAP participation is associated with improved food security. The study is the largest and most rigorous one...

  12. Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23.

    Directory of Open Access Journals (Sweden)

    Jens P Weber

    Full Text Available Synchronization of neurotransmitter release with the presynaptic action potential is essential for maintaining fidelity of information transfer in the central nervous system. However, synchronous release is frequently accompanied by an asynchronous release component that builds up during repetitive stimulation, and can even play a dominant role in some synapses. Here, we show that substitution of SNAP-23 for SNAP-25 in mouse autaptic glutamatergic hippocampal neurons results in asynchronous release and a higher frequency of spontaneous release events (mEPSCs. Use of neurons from double-knock-out (SNAP-25, synaptotagmin-7 mice in combination with viral transduction showed that SNAP-23-driven release is triggered by endogenous synaptotagmin-7. In the absence of synaptotagmin-7 release became even more asynchronous, and the spontaneous release rate increased even more, indicating that synaptotagmin-7 acts to synchronize release and suppress spontaneous release. However, compared to synaptotagmin-1, synaptotagmin-7 is a both leaky and asynchronous calcium sensor. In the presence of SNAP-25, consequences of the elimination of synaptotagmin-7 were small or absent, indicating that the protein pairs SNAP-25/synaptotagmin-1 and SNAP-23/synaptotagmin-7 might act as mutually exclusive calcium sensors. Expression of fusion proteins between pHluorin (pH-sensitive GFP and synaptotagmin-1 or -7 showed that vesicles that fuse using the SNAP-23/synaptotagmin-7 combination contained synaptotagmin-1, while synaptotagmin-7 barely displayed activity-dependent trafficking between vesicle and plasma membrane, implying that it acts as a plasma membrane calcium sensor. Overall, these findings support the idea of alternative syt∶SNARE combinations driving release with different kinetics and fidelity.

  13. Diagnosing Snapping Sartorius Tendon Secondary to a Meniscal Cyst Using Dynamic Ultrasound Avoids Incorrect Surgical Procedure

    Directory of Open Access Journals (Sweden)

    Vipin Asopa

    2013-01-01

    Full Text Available We describe a case of painful snapping in the medial aspect of the knee of a 40-year-old man, following a knee hyperflexion injury. Dynamic real-time ultrasonography determined that the snapping was due to the distal tendon of sartorius passing over a medial meniscal cyst. The patient subsequently underwent arthroscopic decompression of the cyst instead of an inappropriate hamstring tendon harvest procedure, with complete resolution of symptoms.

  14. Growth In SNAP Retailers Was Associated With Increased Client Enrollment In Georgia During The Great Recession.

    Science.gov (United States)

    Shannon, Jerry; Shannon, Sarah; Adams, Grace Bagwell; Lee, Jung Sun

    2016-11-01

    Policies to improve food accessibility in underserved areas often use direct financial incentives to attract new food retailers. Our analysis of data on the Supplemental Nutrition Assistance Program (SNAP) in Georgia before and after the Great Recession suggests that increased program enrollment improves access to food for SNAP beneficiaries by acting as an indirect subsidy to retailers. We divided food stores into four categories: large, midsize, small, and specialty retailers. Between 2008 and 2011 the number of SNAP enrollees increased by 87 percent, and between 2007 and 2014 the number of SNAP retailers in Georgia increased by 82 percent, primarily because of growth in the number of authorized small retailers. Inside metropolitan Atlanta, changes in the numbers of SNAP enrollees and authorized retailers were positively and significantly associated for small retailers. For the areas outside of metropolitan Atlanta, the association between changes in numbers of enrollees and authorized retailers was strongest for small retailers; more modest associations were also seen for large and specialty retailers. Policy makers should consider how retailers' sensitivity to and reliance on SNAP funding can be leveraged to improve not only food availability, but also access to healthy foods. Project HOPE—The People-to-People Health Foundation, Inc.

  15. A single amino acid mutation in SNAP-25 induces anxiety-related behavior in mouse.

    Directory of Open Access Journals (Sweden)

    Masakazu Kataoka

    Full Text Available Synaptosomal-associated protein of 25 kDa (SNAP-25 is a presynaptic protein essential for neurotransmitter release. Previously, we demonstrate that protein kinase C (PKC phosphorylates Ser(187 of SNAP-25, and enhances neurotransmitter release by recruiting secretory vesicles near to the plasma membrane. As PKC is abundant in the brain and SNAP-25 is essential for synaptic transmission, SNAP-25 phosphorylation is likely to play a crucial role in the central nervous system. We therefore generated a mutant mouse, substituting Ser(187 of SNAP-25 with Ala using "knock-in" technology. The most striking effect of the mutation was observed in their behavior. The homozygous mutant mice froze readily in response to environmental change, and showed strong anxiety-related behavior in general activity and light and dark preference tests. In addition, the mutant mice sometimes exhibited spontaneously occurring convulsive seizures. Microdialysis measurements revealed that serotonin and dopamine release were markedly reduced in amygdala. These results clearly indicate that PKC-dependent SNAP-25 phosphorylation plays a critical role in the regulation of emotional behavior as well as the suppression of epileptic seizures, and the lack of enhancement of monoamine release is one of the possible mechanisms underlying these defects.

  16. Multiscalar production amplitudes beyond threshold

    CERN Document Server

    Argyres, E N; Kleiss, R H

    1993-01-01

    We present exact tree-order amplitudes for $H^* \\to n~H$, for final states containing one or two particles with non-zero three-momentum, for various interaction potentials. We show that there are potentials leading to tree amplitudes that satisfy unitarity, not only at threshold but also in the above kinematical configurations and probably beyond. As a by-product, we also calculate $2\\to n$ tree amplitudes at threshold and show that for the unbroken $\\phi^4$ theory they vanish for $n>4~$, for the Standard Model Higgs they vanish for $n\\ge 3~$ and for a model potential, respecting tree-order unitarity, for $n$ even and $n>4~$. Finally, we calculate the imaginary part of the one-loop $1\\to n$ amplitude in both symmetric and spontaneously broken $\\phi^4$ theory.

  17. Scattering amplitudes in gauge theories

    CERN Document Server

    Henn, Johannes M

    2014-01-01

    At the fundamental level, the interactions of elementary particles are described by quantum gauge field theory. The quantitative implications of these interactions are captured by scattering amplitudes, traditionally computed using Feynman diagrams. In the past decade tremendous progress has been made in our understanding of and computational abilities with regard to scattering amplitudes in gauge theories, going beyond the traditional textbook approach. These advances build upon on-shell methods that focus on the analytic structure of the amplitudes, as well as on their recently discovered hidden symmetries. In fact, when expressed in suitable variables the amplitudes are much simpler than anticipated and hidden patterns emerge.   These modern methods are of increasing importance in phenomenological applications arising from the need for high-precision predictions for the experiments carried out at the Large Hadron Collider, as well as in foundational mathematical physics studies on the S-matrix in quantum ...

  18. Amplitude damping of vortex modes

    CSIR Research Space (South Africa)

    Dudley, Angela L

    2010-09-01

    Full Text Available An interferometer, mimicking an amplitude damping channel for vortex modes, is presented. Experimentally the action of the channel is in good agreement with that predicted theoretically. Since we can characterize the action of the channel on orbital...

  19. Appetite - decreased

    Science.gov (United States)

    Loss of appetite; Decreased appetite; Anorexia ... Any illness can reduce appetite. If the illness is treatable, the appetite should return when the condition is cured. Loss of appetite can cause weight ...

  20. Motivic amplitudes and cluster coordinates

    International Nuclear Information System (INIS)

    Golden, J.K.; Goncharov, A.B.; Spradlin, M.; Vergu, C.; Volovich, A.

    2014-01-01

    In this paper we study motivic amplitudes — objects which contain all of the essential mathematical content of scattering amplitudes in planar SYM theory in a completely canonical way, free from the ambiguities inherent in any attempt to choose particular functional representatives. We find that the cluster structure on the kinematic configuration space Conf n (ℙ 3 ) underlies the structure of motivic amplitudes. Specifically, we compute explicitly the coproduct of the two-loop seven-particle MHV motivic amplitude A 7,2 M and find that like the previously known six-particle amplitude, it depends only on certain preferred coordinates known in the mathematics literature as cluster X-coordinates on Conf n (ℙ 3 ). We also find intriguing relations between motivic amplitudes and the geometry of generalized associahedrons, to which cluster coordinates have a natural combinatoric connection. For example, the obstruction to A 7,2 M being expressible in terms of classical polylogarithms is most naturally represented by certain quadrilateral faces of the appropriate associahedron. We also find and prove the first known functional equation for the trilogarithm in which all 40 arguments are cluster X-coordinates of a single algebra. In this respect it is similar to Abel’s 5-term dilogarithm identity

  1. SnapVideo: Personalized Video Generation for a Sightseeing Trip.

    Science.gov (United States)

    Zhang, Luming; Jing, Peiguang; Su, Yuting; Zhang, Chao; Shaoz, Ling

    2017-11-01

    Leisure tourism is an indispensable activity in urban people's life. Due to the popularity of intelligent mobile devices, a large number of photos and videos are recorded during a trip. Therefore, the ability to vividly and interestingly display these media data is a useful technique. In this paper, we propose SnapVideo, a new method that intelligently converts a personal album describing of a trip into a comprehensive, aesthetically pleasing, and coherent video clip. The proposed framework contains three main components. The scenic spot identification model first personalizes the video clips based on multiple prespecified audience classes. We then search for some auxiliary related videos from YouTube 1 according to the selected photos. To comprehensively describe a scenery, the view generation module clusters the crawled video frames into a number of views. Finally, a probabilistic model is developed to fit the frames from multiple views into an aesthetically pleasing and coherent video clip, which optimally captures the semantics of a sightseeing trip. Extensive user studies demonstrated the competitiveness of our method from an aesthetic point of view. Moreover, quantitative analysis reflects that semantically important spots are well preserved in the final video clip. 1 https://www.youtube.com/.

  2. Contactless, photoinitiated snap-through in azobenzene-functionalized polymers.

    Science.gov (United States)

    Shankar, M Ravi; Smith, Matthew L; Tondiglia, Vincent P; Lee, Kyung Min; McConney, Michael E; Wang, David H; Tan, Loon-Seng; White, Timothy J

    2013-11-19

    Photomechanical effects in polymeric materials and composites transduce light into mechanical work. The ability to control the intensity, polarization, placement, and duration of light irradiation is a distinctive and potentially useful tool to tailor the location, magnitude, and directionality of photogenerated mechanical work. Unfortunately, the work generated from photoresponsive materials is often slow and yields very small power densities, which diminish their potential use in applications. Here, we investigate photoinitiated snap-through in bistable arches formed from samples composed of azobenzene-functionalized polymers (both amorphous polyimides and liquid crystal polymer networks) and report orders-of-magnitude enhancement in actuation rates (approaching 10(2) mm/s) and powers (as much as 1 kW/m(3)). The contactless, ultra-fast actuation is observed at irradiation intensities focusing on isolating the role of sample geometry, mechanical properties of the materials, and photomechanical strain. Using light to trigger contactless, ultrafast actuation in an otherwise passive structure is a potentially versatile tool to use in mechanical design at the micro-, meso-, and millimeter scales as actuators, as well as switches that can be triggered from large standoff distances, impulse generators for microvehicles, microfluidic valves and mixers in laboratory-on-chip devices, and adaptive optical elements.

  3. The reduced serum free triiodothyronine and increased dorsal hippocampal SNAP-25 and Munc18-1 had existed in middle-aged CD-1 mice with mild spatial cognitive impairment.

    Science.gov (United States)

    Cao, Lei; Jiang, Wei; Wang, Fang; Yang, Qi-Gang; Wang, Chao; Chen, Yong-Ping; Chen, Gui-Hai

    2013-12-02

    Changes of synaptic proteins in highlighted brain regions and decreased serum thyroid hormones (THs) have been implied in age-related learning and memory decline. Previously, we showed significant pairwise correlations among markedly impaired spatial learning and memory ability, decreased serum free triiodothyronine (FT3) and increased hippocampal SNAP-25 and Munc18-1 in old Kunming mice. However, whether these changes and the correlations occur in middle-age mice remains unclear. Since this age is one of the best stages to study age-related cognitive decline, we explored the spatial learning and memory ability, serum THs, cerebral SNAP-25 and Munc18-1 levels and their relationships of middle-aged mice in this study. The learning and memory abilities of 35 CD-1 mice (19 mice aged 6 months and 16 mice aged 12 months) were measured with a radial six-arm water maze (RAWM). The SNAP-25 and Munc18-1 levels were semi-quantified by Western blotting and the serum THs were detected by radioimmunoassay. The results showed the middle-aged mice had decreased serum FT3, increased dorsal hippocampal (DH) SNAP-25 and Munc18-1, and many or long number of errors and latency in both learning and memory phases of the RAWM. The Pearson's correlation test showed that the DH SANP-25 and Munc18-1 levels were positively correlated with the number of errors and latency in learning phases of the RAWM. Meanwhile, the DH SANP-25 and Munc18-1 levels negatively correlated with the serum FT3 level. These results suggested that reduced FT3 with increased DH SNAP-25 and Munc18-1 levels might be involved in the spatial learning ability decline in the middle-aged mice. © 2013 Elsevier B.V. All rights reserved.

  4. Temperature-dependent sex determination modulates cardiovascular maturation in embryonic snapping turtles Chelydra serpentina.

    Science.gov (United States)

    Alvine, Travis; Rhen, Turk; Crossley, Dane A

    2013-03-01

    We investigated sex differences in cardiovascular maturation in embryos of the snapping turtle Chelydra serpentina, a species with temperature-dependent sex determination. One group of eggs was incubated at 26.5°C to produce males. Another group of eggs was incubated at 26.5°C until embryos reached stage 17; eggs were then shifted to 31°C for 6 days to produce females, and returned to 26.5°C for the rest of embryogenesis. Thus, males and females were at the same temperature when autonomic tone was determined and for most of development. Cholinergic blockade increased resting blood pressure (P(m)) and heart rate (f(H)) in both sexes at 75% and 90% of incubation. However, the magnitude of the f(H) response was enhanced in males compared with females at 90% of incubation. β-adrenergic blockade increased P(m) at 75% of incubation in both sexes but had no effect at 90% of incubation. β-adrenergic blockade reduced f(H) at both time points but produced a stronger response at 90% versus 75% of incubation. We found that α-adrenergic blockade decreased P(m) in both sexes at 75% and 90% of incubation and decreased f(H) at 75% of incubation in both sexes. At 90% of incubation, f(H) decreased in females but not males. Although these data clearly demonstrate sexual dimorphism in the autonomic regulation of cardiovascular physiology in embryos, further studies are needed to test whether differences are caused by endocrine signals from gonads or by a hormone-independent temperature effect.

  5. Recent Developments in the Recovery of SNAP-DYN Technical Data Base

    Science.gov (United States)

    Determan, William R.; Grimmett, David

    2007-01-01

    SNAP-DYN was a concept for a multi-kilowatt class (i.e., 10 to 50 kWe) of space nuclear electric power systems based on the SNAP reactor, shield, and liquid metal heat transfer technologies developed in the 1960s and coupled with dynamic power conversion hardware and state of the art space radiator technologies. The basic concept minimized the system's development costs by utilizing established technologies for each of the major components within the power system to reduce its overall development schedule. Three power conversion technologies were evaluated for the SNAP-DYN concept including Organic Rankine Cycle (ORC) with a peak cycle temperature of 672 K, a closed Brayton cycle (CBC) with a peak cycle temperature of 906 K, and a free piston Stirling cycle (FPSC) with a peak cycle temperature of 870 K. Net system conversion efficiencies were estimated to range from 16 to 19 % over the 10 to 50 kWe power range. Specific power levels for these systems were estimated to range from 6.4 to 13 W/kg over the same power range. SNAP-DYN reactor thermal power levels varied from 55 to 260 kWt, but a much longer lifetime (5 to 10 years vs. 1.3 years) was being evaluated for this power system application than had been demonstrated in the 1960s SNAP reactor development program. The last SNAP reactor under development at the end of the program in 1973 was designed for a 5-year mission life at a nominal thermal power level of 110 kWt with a coolant outlet temperature capability of 922 K. This reactor technology formed the basis for the SNAP-DYN reactor concept.

  6. Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration.

    Science.gov (United States)

    Hoerder-Suabedissen, Anna; Korrell, Kim V; Hayashi, Shuichi; Jeans, Alexander; Ramirez, Denise M O; Grant, Eleanor; Christian, Helen C; Kavalali, Ege T; Wilson, Michael C; Molnár, Zoltán

    2018-05-30

    Synaptosomal associated protein 25 kDa (SNAP25) is an essential component of the SNARE complex regulating synaptic vesicle fusion. SNAP25 deficiency has been implicated in a variety of cognitive disorders. We ablated SNAP25 from selected neuronal populations by generating a transgenic mouse (B6-Snap25tm3mcw (Snap25-flox)) with LoxP sites flanking exon5a/5b. In the presence of Cre-recombinase, Snap25-flox is recombined to a truncated transcript. Evoked synaptic vesicle release is severely reduced in Snap25 conditional knockout (cKO) neurons as shown by live cell imaging of synaptic vesicle fusion and whole cell patch clamp recordings in cultured hippocampal neurons. We studied Snap25 cKO in subsets of cortical projection neurons in vivo (L5-Rbp4-Cre; L6-Ntsr1-Cre; L6b-Drd1a-Cre). cKO neurons develop normal axonal projections, but axons are not maintained appropriately, showing signs of swelling, fragmentation and eventually complete absence. Onset and progression of degeneration are dependent on the neuron type, with L5 cells showing the earliest and most severe axonal loss. Ultrastructural examination revealed that cKO neurites contain autophagosome/lysosome-like structures. Markers of inflammation such as Iba1 and lipofuscin are increased only in adult cKO cortex. Snap25 cKO can provide a model to study genetic interactions with environmental influences in several disorders.

  7. Strategies to improve the dietary quality of Supplemental Nutrition Assistance Program (SNAP) beneficiaries: an assessment of stakeholder opinions.

    Science.gov (United States)

    Blumenthal, Susan J; Hoffnagle, Elena E; Leung, Cindy W; Lofink, Hayley; Jensen, Helen H; Foerster, Susan B; Cheung, Lilian Wy; Nestle, Marion; Willett, Walter C

    2014-12-01

    To examine the opinions of stakeholders on strategies to improve dietary quality of Supplemental Nutrition Assistance Program (SNAP) participants. Participants answered a thirty-eight-item web-based survey assessing opinions and perceptions of SNAP and programme policy changes. Survey of 522 individuals with stakeholder interest in SNAP, conducted in October through December 2011. The top three barriers to improving dietary quality identified were: (i) unhealthy foods marketed in low-income communities; (ii) the high cost of healthy foods; and (iii) lifestyle challenges faced by low-income individuals. Many respondents (70 %) also disagreed that current SNAP benefit levels were adequate to maintain a healthy diet. Stakeholders believed that vouchers, coupons or monetary incentives for purchasing healthful foods might have the greatest potential for improving the diets of SNAP participants. Many respondents (78 %) agreed that sodas should not be eligible for purchases with SNAP benefits. More than half (55 %) believed retailers could easily implement such restrictions. A majority of respondents (58 %) agreed that stores should stock a minimum quantity of healthful foods in order to be certified as a SNAP retailer, and most respondents (83 %) believed that the US Department of Agriculture should collect data on the foods purchased with SNAP benefits. Results suggest that there is broad stakeholder support for policies that align SNAP purchase eligibility with national public health goals of reducing food insecurity, improving nutrition and preventing obesity.

  8. Nonsinglet pentagons and NMHV amplitudes

    Directory of Open Access Journals (Sweden)

    A.V. Belitsky

    2015-07-01

    Full Text Available Scattering amplitudes in maximally supersymmetric gauge theory receive a dual description in terms of the expectation value of the super Wilson loop stretched on a null polygonal contour. This makes the analysis amenable to nonperturbative techniques. Presently, we elaborate on a refined form of the operator product expansion in terms of pentagon transitions to compute twist-two contributions to NMHV amplitudes. To start with, we provide a novel derivation of scattering matrices starting from Baxter equations for flux-tube excitations propagating on magnon background. We propose bootstrap equations obeyed by pentagon form factors with nonsinglet quantum numbers with respect to the R-symmetry group and provide solutions to them to all orders in 't Hooft coupling. These are then successfully confronted against available perturbative calculations for NMHV amplitudes to four-loop order.

  9. Nonsinglet pentagons and NMHV amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Belitsky, A.V., E-mail: andrei.belitsky@asu.edu

    2015-07-15

    Scattering amplitudes in maximally supersymmetric gauge theory receive a dual description in terms of the expectation value of the super Wilson loop stretched on a null polygonal contour. This makes the analysis amenable to nonperturbative techniques. Presently, we elaborate on a refined form of the operator product expansion in terms of pentagon transitions to compute twist-two contributions to NMHV amplitudes. To start with, we provide a novel derivation of scattering matrices starting from Baxter equations for flux-tube excitations propagating on magnon background. We propose bootstrap equations obeyed by pentagon form factors with nonsinglet quantum numbers with respect to the R-symmetry group and provide solutions to them to all orders in 't Hooft coupling. These are then successfully confronted against available perturbative calculations for NMHV amplitudes to four-loop order.

  10. Cluster polylogarithms for scattering amplitudes

    International Nuclear Information System (INIS)

    Golden, John; Paulos, Miguel F; Spradlin, Marcus; Volovich, Anastasia

    2014-01-01

    Motivated by the cluster structure of two-loop scattering amplitudes in N=4 Yang-Mills theory we define cluster polylogarithm functions. We find that all such functions of weight four are made up of a single simple building block associated with the A 2 cluster algebra. Adding the requirement of locality on generalized Stasheff polytopes, we find that these A 2 building blocks arrange themselves to form a unique function associated with the A 3 cluster algebra. This A 3 function manifests all of the cluster algebraic structure of the two-loop n-particle MHV amplitudes for all n, and we use it to provide an explicit representation for the most complicated part of the n = 7 amplitude as an example. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Cluster algebras in mathematical physics’. (paper)

  11. Topological amplitudes in string theory

    International Nuclear Information System (INIS)

    Antoniadis, I.; Taylor, T.R.

    1993-07-01

    We show that certain type II string amplitudes at genus g are given by the topological partition F g discussed recently by Bershadsky, Cecotti, Ooguri and Vafa. These amplitudes give rise to a term in the four-dimensional effective action of the form Σ g F g W 2g , where W is the chiral superfield of N = 2 supergravitational multiplet. The holomorphic anomaly of F g is related to non-localities of the effective action due to the propagation of massless states. This result generalizes the holomorphic anomaly of the one loop case which is known to lead to non-harmonic gravitational couplings. (author). 22 refs, 2 figs

  12. Accommodative Amplitude in School-Age Children

    Directory of Open Access Journals (Sweden)

    Ikaunieks Gatis

    2017-10-01

    Full Text Available In children, intensive near-work affects the accommodation system of the eye. Younger children, due to anatomical parameters, read at smaller distance than older children and we can expect that the accommodation system of younger can be affected more than that of older children. We wanted to test this hypothesis. Some authors showed that the norms of amplitude of accommodation (AA developed by Hofstetter (1950 not always could be applied for children. We also wanted to verify these results. A total of 106 (age 7-15 children participated in the study. Distance visual acuity was measured for all children and only data of children with good visual acuity 1.0 or more (dec. units were analysed (73 children. Accommodative amplitude was measured before and after lessons using subjective push-up technique (with RAF Near Point Ruler. The results showed that the amplitude of accommodation reduced significantly (p < 0.05 during the day and decrease of AA was similar in different age groups (about ~0.70 D. Additional measurements are needed to verify that the observed changes in AA were associated with fatigue effect. The results showed lower accommodation values compared to average values calculated according to the Hofstetter equation (p < 0.05.

  13. N-loop string amplitude

    International Nuclear Information System (INIS)

    Mandelstam, S.

    1986-06-01

    Work on the derivation of an explicit perturbation series for string and superstring amplitudes is reviewed. The light-cone approach is emphasized, but some work on the Polyakov approach is also mentioned, and the two methods are compared. The calculation of the measure factor is outlined in the interacting-string picture

  14. Scattering Amplitudes from Intersection Theory.

    Science.gov (United States)

    Mizera, Sebastian

    2018-04-06

    We use Picard-Lefschetz theory to prove a new formula for intersection numbers of twisted cocycles associated with a given arrangement of hyperplanes. In a special case when this arrangement produces the moduli space of punctured Riemann spheres, intersection numbers become tree-level scattering amplitudes of quantum field theories in the Cachazo-He-Yuan formulation.

  15. Positivity of spin foam amplitudes

    International Nuclear Information System (INIS)

    Baez, John C; Christensen, J Daniel

    2002-01-01

    The amplitude for a spin foam in the Barrett-Crane model of Riemannian quantum gravity is given as a product over its vertices, edges and faces, with one factor of the Riemannian 10j symbols appearing for each vertex, and simpler factors for the edges and faces. We prove that these amplitudes are always nonnegative for closed spin foams. As a corollary, all open spin foams going between a fixed pair of spin networks have real amplitudes of the same sign. This means one can use the Metropolis algorithm to compute expectation values of observables in the Riemannian Barrett-Crane model, as in statistical mechanics, even though this theory is based on a real-time (e iS ) rather than imaginary-time e -S path integral. Our proof uses the fact that when the Riemannian 10j symbols are nonzero, their sign is positive or negative depending on whether the sum of the ten spins is an integer or half-integer. For the product of 10j symbols appearing in the amplitude for a closed spin foam, these signs cancel. We conclude with some numerical evidence suggesting that the Lorentzian 10j symbols are always nonnegative, which would imply similar results for the Lorentzian Barrett-Crane model

  16. Employing Helicity Amplitudes for Resummation

    NARCIS (Netherlands)

    Moult, I.; Stewart, I.W.; Tackmann, F.J.; Waalewijn, W.J.

    2015-01-01

    Many state-of-the-art QCD calculations for multileg processes use helicity amplitudes as their fundamental ingredients. We construct a simple and easy-to-use helicity operator basis in soft-collinear effective theory (SCET), for which the hard Wilson coefficients from matching QCD onto SCET are

  17. Scattering amplitudes in gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Henn, Johannes M. [Institute for Advanced Study, Princeton, NJ (United States). School of Natural Sciences; Plefka, Jan C. [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik

    2014-03-01

    First monographical text on this fundamental topic. Course-tested, pedagogical and self-contained exposition. Includes exercises and solutions. At the fundamental level, the interactions of elementary particles are described by quantum gauge field theory. The quantitative implications of these interactions are captured by scattering amplitudes, traditionally computed using Feynman diagrams. In the past decade tremendous progress has been made in our understanding of and computational abilities with regard to scattering amplitudes in gauge theories, going beyond the traditional textbook approach. These advances build upon on-shell methods that focus on the analytic structure of the amplitudes, as well as on their recently discovered hidden symmetries. In fact, when expressed in suitable variables the amplitudes are much simpler than anticipated and hidden patterns emerge. These modern methods are of increasing importance in phenomenological applications arising from the need for high-precision predictions for the experiments carried out at the Large Hadron Collider, as well as in foundational mathematical physics studies on the S-matrix in quantum field theory. Bridging the gap between introductory courses on quantum field theory and state-of-the-art research, these concise yet self-contained and course-tested lecture notes are well-suited for a one-semester graduate level course or as a self-study guide for anyone interested in fundamental aspects of quantum field theory and its applications. The numerous exercises and solutions included will help readers to embrace and apply the material presented in the main text.

  18. Scattering amplitudes in gauge theories

    International Nuclear Information System (INIS)

    Henn, Johannes M.; Plefka, Jan C.

    2014-01-01

    First monographical text on this fundamental topic. Course-tested, pedagogical and self-contained exposition. Includes exercises and solutions. At the fundamental level, the interactions of elementary particles are described by quantum gauge field theory. The quantitative implications of these interactions are captured by scattering amplitudes, traditionally computed using Feynman diagrams. In the past decade tremendous progress has been made in our understanding of and computational abilities with regard to scattering amplitudes in gauge theories, going beyond the traditional textbook approach. These advances build upon on-shell methods that focus on the analytic structure of the amplitudes, as well as on their recently discovered hidden symmetries. In fact, when expressed in suitable variables the amplitudes are much simpler than anticipated and hidden patterns emerge. These modern methods are of increasing importance in phenomenological applications arising from the need for high-precision predictions for the experiments carried out at the Large Hadron Collider, as well as in foundational mathematical physics studies on the S-matrix in quantum field theory. Bridging the gap between introductory courses on quantum field theory and state-of-the-art research, these concise yet self-contained and course-tested lecture notes are well-suited for a one-semester graduate level course or as a self-study guide for anyone interested in fundamental aspects of quantum field theory and its applications. The numerous exercises and solutions included will help readers to embrace and apply the material presented in the main text.

  19. Employing helicity amplitudes for resummation

    International Nuclear Information System (INIS)

    Moult, Ian; Stewart, Iain W.; Tackmann, Frank J.; Waalewijn, Wouter J.; Amsterdam Univ.

    2015-08-01

    Many state-of-the-art QCD calculations for multileg processes use helicity amplitudes as their fundamental ingredients. We construct a simple and easy-to-use helicity operator basis in soft-collinear effective theory (SCET), for which the hard Wilson coefficients from matching QCD onto SCET are directly given in terms of color-ordered helicity amplitudes. Using this basis allows one to seamlessly combine fixed-order helicity amplitudes at any order they are known with a resummation of higher-order logarithmic corrections. In particular, the virtual loop amplitudes can be employed in factorization theorems to make predictions for exclusive jet cross sections without the use of numerical subtraction schemes to handle real-virtual infrared cancellations. We also discuss matching onto SCET in renormalization schemes with helicities in 4- and d-dimensions. To demonstrate that our helicity operator basis is easy to use, we provide an explicit construction of the operator basis, as well as results for the hard matching coefficients, for pp → H+0,1,2 jets, pp → W/Z/γ+0,1,2 jets, and pp → 2,3 jets. These operator bases are completely crossing symmetric, so the results can easily be applied to processes with e + e - and e - p collisions.

  20. Discontinuity formulas for multiparticle amplitudes

    International Nuclear Information System (INIS)

    Stapp, H.P.

    1976-03-01

    It is shown how discontinuity formulas for multiparticle scattering amplitudes are derived from unitarity and analyticity. The assumed analyticity property is the normal analytic structure, which was shown to be equivalent to the space-time macrocausality condition. The discontinuity formulas to be derived are the basis of multi-particle fixed-t dispersion relations

  1. Distribution amplitudes of vector mesons

    Energy Technology Data Exchange (ETDEWEB)

    Braun, V.M. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Broemmel, D. [Deutsches Elektronen-Synchrotron, Hamburg (Germany); Goeckeler, M. [Regensburg Univ. (DE). Inst. fuer Theoretische Physik] (and others)

    2007-11-15

    Results are presented for the lowest moment of the distribution amplitude for the K{sup *} vector meson. Both longitudinal and transverse moments are investigated. We use two flavours of O(a) improved Wilson fermions, together with a non-perturbative renormalisation of the matrix element. (orig.)

  2. Elementary amplitudes from full QCD and the stochastic vacuum model

    International Nuclear Information System (INIS)

    Martini, A.F.; Menon, M.J.

    2002-01-01

    In a previous work, making use of the gluon gauge-invariant two-point correlation function determined from lattice QCD in the quenched approximation and the stochastic vacuum model, we determined the elementary (parton-parton) scattering amplitude in the momentum transfer space. In this communication we compute the elementary amplitude from new lattice QCD calculations that include the effects of dynamical fermions (full QCD). The main conclusion is that the inclusion of dynamical fermions leads to a normalized elementary amplitude that decreases more quickly with the momentum transfer than that in the quenched approximation. (author)

  3. In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [11C]SNAP-7941 and [18F]FE@SNAP reveal specific uptake in the ventricular system.

    Science.gov (United States)

    Zeilinger, Markus; Dumanic, Monika; Pichler, Florian; Budinsky, Lubos; Wadsak, Wolfgang; Pallitsch, Katharina; Spreitzer, Helmut; Lanzenberger, Rupert; Hacker, Marcus; Mitterhauser, Markus; Philippe, Cécile

    2017-08-14

    The MCHR1 is involved in the regulation of energy homeostasis and changes of the expression are linked to a variety of associated diseases, such as diabetes and adiposity. The study aimed at the in vitro and in vivo evaluation of [ 11 C]SNAP-7941 and [ 18 F]FE@SNAP as potential PET-tracers for the MCHR1. Competitive binding studies with non-radioactive derivatives and small-animal PET/CT and MRI brain studies were performed under baseline conditions and tracer displacement with the unlabelled MCHR1 antagonist (±)-SNAP-7941. Binding studies evinced high binding affinity of the non-radioactive derivatives. Small-animal imaging of [ 11 C]SNAP-7941 and [ 18 F]FE@SNAP evinced high tracer uptake in MCHR1-rich regions of the ventricular system. Quantitative analysis depicted a significant tracer reduction after displacement with (±)-SNAP-7941. Due to the high binding affinity of the non-labelled derivatives and the high specific tracer uptake of [ 11 C]SNAP-7941 and [ 18 F]FE@SNAP, there is strong evidence that both radiotracers may serve as highly suitable agents for specific MCHR1 imaging.

  4. Tuning and switching of band gap of the periodically undulated beam by the snap through buckling

    Directory of Open Access Journals (Sweden)

    Y. Li

    2017-05-01

    Full Text Available We propose highly tuning and switching band gaps of phononic crystals through the snap through buckling by investigating wave propagation in a designed tractable undulated beam with single material and periodically arched shape. A series of numerical analyses are conducted to offer a thorough understanding of the evolution of the band gaps as a function of the vertical applied load. We find out that the interesting snap through buckling induced by the vertical load can alter the width of the band gap of the undulated beam dramatically, even switch them on and off. Our researches show an effective strategy to tune the band gaps of phononic crystals through the snap through buckling behavior.

  5. Polycyclic aromatic hydrocarbons affect survival and development of common snapping turtle (Chelydra serpentina) embryos and hatchlings.

    Science.gov (United States)

    Van Meter, Robin J; Spotila, James R; Avery, Harold W

    2006-08-01

    Polycyclic aromatic hydrocarbons (PAHs) are toxic compounds found in the John Heinz National Wildlife Refuge in Philadelphia, Pennsylvania. We assessed the impact of PAHs and crude oil on snapping turtle development and behavior by exposing snapping turtle eggs from the Refuge and from three clean reference sites to individual PAHs or a crude oil mixture at stage 9 of embryonic development. Exposure to PAHs had a significant effect on survival rates in embryos from one clean reference site, but not in embryos from the other sites. There was a positive linear relationship between level of exposure to PAHs and severity of deformities in embryos collected from two of the clean reference sites. Neither righting response nor upper temperature tolerance (critical thermal maximum, CTM) of snapping turtle hatchlings with no or minor deformities was significantly affected by exposure to PAHs.

  6. Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23

    DEFF Research Database (Denmark)

    Weber, Jens P; Toft-Bertelsen, Trine L; Mohrmann, Ralf

    2014-01-01

    Synchronization of neurotransmitter release with the presynaptic action potential is essential for maintaining fidelity of information transfer in the central nervous system. However, synchronous release is frequently accompanied by an asynchronous release component that builds up during repetitive...... stimulation, and can even play a dominant role in some synapses. Here, we show that substitution of SNAP-23 for SNAP-25 in mouse autaptic glutamatergic hippocampal neurons results in asynchronous release and a higher frequency of spontaneous release events (mEPSCs). Use of neurons from double-knock-out (SNAP......, while synaptotagmin-7 barely displayed activity-dependent trafficking between vesicle and plasma membrane, implying that it acts as a plasma membrane calcium sensor. Overall, these findings support the idea of alternative syt∶SNARE combinations driving release with different kinetics and fidelity....

  7. SNAP Participants' Eating Patterns over the Benefit Month: A Time Use Perspective.

    Directory of Open Access Journals (Sweden)

    Karen S Hamrick

    Full Text Available Individuals receiving monthly benefits through the U.S. Supplemental Nutrition Assistance Program (SNAP often fall short of food at the end of the month and some report feelings of hunger. To investigate this situation, we used time diaries from the 2006-08 American Time Use Survey and Eating & Health Module to identify the timing of days where respondents reported no eating occurrences. Analysis includes descriptive statistics, a logit model, and a simulated benefit month. We found that SNAP participants were increasingly more likely than nonparticipants to report a day with no eating occurrences over the benefit issuance cycle. This supports the view that there is a monthly cycle in food consumption associated with the SNAP monthly benefit issuance policy.

  8. SNAP Participants’ Eating Patterns over the Benefit Month: A Time Use Perspective

    Science.gov (United States)

    2016-01-01

    Individuals receiving monthly benefits through the U.S. Supplemental Nutrition Assistance Program (SNAP) often fall short of food at the end of the month and some report feelings of hunger. To investigate this situation, we used time diaries from the 2006–08 American Time Use Survey and Eating & Health Module to identify the timing of days where respondents reported no eating occurrences. Analysis includes descriptive statistics, a logit model, and a simulated benefit month. We found that SNAP participants were increasingly more likely than nonparticipants to report a day with no eating occurrences over the benefit issuance cycle. This supports the view that there is a monthly cycle in food consumption associated with the SNAP monthly benefit issuance policy. PMID:27410962

  9. SNAP Participants' Eating Patterns over the Benefit Month: A Time Use Perspective.

    Science.gov (United States)

    Hamrick, Karen S; Andrews, Margaret

    2016-01-01

    Individuals receiving monthly benefits through the U.S. Supplemental Nutrition Assistance Program (SNAP) often fall short of food at the end of the month and some report feelings of hunger. To investigate this situation, we used time diaries from the 2006-08 American Time Use Survey and Eating & Health Module to identify the timing of days where respondents reported no eating occurrences. Analysis includes descriptive statistics, a logit model, and a simulated benefit month. We found that SNAP participants were increasingly more likely than nonparticipants to report a day with no eating occurrences over the benefit issuance cycle. This supports the view that there is a monthly cycle in food consumption associated with the SNAP monthly benefit issuance policy.

  10. The development of Version 2 of the AN-SNAP casemix classification system.

    Science.gov (United States)

    Green, Janette; Gordon, Robert

    2007-04-01

    This paper presents the results of a recent review of the Australian National Sub-acute and Non-acute Patient (AN-SNAP) classification system. The AN-SNAP system was developed by the Centre for Health Service Development, University of Wollongong in 1997. The review was conducted between August 2005 and September 2006. Four clinical sub-committees comprising more than 50 clinicians from sub-acute services across New South Wales as well as representatives from Queensland and the Australian Capital Territory were established to develop a set of proposals to be considered for incorporation into Version 2 of the classification. It is proposed that the final AN-SNAP Version 2 classification will be available for implementation from 1 July 2007.

  11. A Brief Description of the Kokkos implementation of the SNAP potential in ExaMiniMD.

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Aidan P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Trott, Christian Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-11-01

    Within the EXAALT project, the SNAP [1] approach is being used to develop high accuracy potentials for use in large-scale long-time molecular dynamics simulations of materials behavior. In particular, we have developed a new SNAP potential that is suitable for describing the interplay between helium atoms and vacancies in high-temperature tungsten[2]. This model is now being used to study plasma-surface interactions in nuclear fusion reactors for energy production. The high-accuracy of SNAP potentials comes at the price of increased computational cost per atom and increased computational complexity. The increased cost is mitigated by improvements in strong scaling that can be achieved using advanced algorithms [3].

  12. Scapulothoracic bursitis and snapping scapula syndrome: a critical review of current evidence.

    Science.gov (United States)

    Warth, Ryan J; Spiegl, Ulrich J; Millett, Peter J

    2015-01-01

    Symptomatic scapulothoracic disorders, such as painful scapular crepitus and/or bursitis, are uncommon; however, they can produce significant pain and disability in many patients. To review the current knowledge pertaining to snapping scapula syndrome and to identify areas of further research that may be helpful to improve clinical outcomes and patient satisfaction. Systematic review. We performed a preliminary search of the PubMed and Embase databases using the search terms "snapping scapula," "scapulothoracic bursitis," "partial scapulectomy," and "superomedial angle resection" in September 2013. All nonreview articles related to the topic of snapping scapula syndrome were included. The search identified a total of 167 unique articles, 81 of which were relevant to the topic of snapping scapula syndrome. There were 36 case series of fewer than 10 patients, 16 technique papers, 11 imaging studies, 9 anatomic studies, and 9 level IV outcomes studies. The level of evidence obtained from this literature search was inadequate to perform a formal systematic review or meta-analysis. Therefore, a critical review of current evidence is presented. Snapping scapula syndrome, a likely underdiagnosed condition, can produce significant shoulder dysfunction in many patients. Because the precise origin is typically unknown, specific treatments that are effective for some patients may not be effective for others. Nevertheless, bursectomy with or without partial scapulectomy is currently the most effective primary method of treatment in patients who fail nonoperative therapy. However, many patients experience continued shoulder disability even after surgical intervention. Future studies should focus on identifying the modifiable factors associated with poor outcomes after operative and nonoperative management for snapping scapula syndrome in an effort to improve clinical outcomes and patient satisfaction. © 2014 The Author(s).

  13. SnapAnatomy, a computer-based interactive tool for independent learning of human anatomy.

    Science.gov (United States)

    Yip, George W; Rajendran, Kanagasuntheram

    2008-06-01

    Computer-aided instruction materials are becoming increasing popular in medical education and particularly in the teaching of human anatomy. This paper describes SnapAnatomy, a new interactive program that the authors designed for independent learning of anatomy. SnapAnatomy is primarily tailored for the beginner student to encourage the learning of anatomy by developing a three-dimensional visualization of human structure that is essential to applications in clinical practice and the understanding of function. The program allows the student to take apart and to accurately put together body components in an interactive, self-paced and variable manner to achieve the learning outcome.

  14. The snap-back effect of an RC-IGBT and its simulations

    International Nuclear Information System (INIS)

    Zhang Wenliang; Tian Xiaoli; Zhu Yangjun; Tan Jingfei

    2013-01-01

    The RC-IGBT (reverse conducting insulated gate bipolar transistor) is a new kind of power semiconductor device which has many advantages such as smaller chip size, higher power density, lower manufacturing cost, softer turn off behavior, and better reliability. However, its performance has a number of drawbacks, such as the snap-back effect. In this paper, an introduction about the snap-back effect of the RC-IGBT is given firstly. Then the physical explanations are presented with two simplified models. After that, some numerical simulations are carried out to verify the correctness of the models. (semiconductor devices)

  15. The sensitivity of graphene “snap-through” to substrate geometry

    KAUST Repository

    Wagner, Till J. W.

    2012-01-01

    We study theoretically the deposition of few layer graphene sheets onto a grooved substrate incorporating adhesion between substrate and sheet. We develop a model to understand the equilibrium of the sheet allowing for partial conformation of sheet to substrate. This model gives physical insight into recent observations of snap-through from flat to conforming states and emphasizes the crucial role of substrate shape in determining the nature of this transition. Our analytical results are consistent with numerical simulations using a van der Waals-like interaction. Finally, we propose a substrate shape that should exhibit a continuous, rather than snap-through, transition. © 2012 American Institute of Physics.

  16. Scruncher phase and amplitude control

    International Nuclear Information System (INIS)

    DeHaven, R.A.; Morris, C.L.; Johnson, R.; Davis, J.; O'Donnell, J.M.

    1992-01-01

    The analog controller for phase and amplitude control of a 402.5 MHz super conducting cavity is described in this paper. The cavity is a single cell with niobium explosively bonded to a copper cavity. It is used as an energy compressor for pions at the Clinton P. Anderson Meson Physics Facility (LAMPF). The controller maintains cavity frequency to within 4 degrees in phase of the LAMPF beam frequency. Field amplitude is maintained to within 2 percent. This control is accomplished at critical coupling (Q load of 1 x 10 9 ) with the use of only a 30 watt rf amplifier for accelerating fields of 6 MV/m. The design includes the use of piezoelectric crystals for fast resonance control. Three types of control, self excited, VCO, and a reference frequency driven, were tried on this cavity and we present a comparison of their performance. (Author) 4 figs., ref

  17. SCRUNCHER phase and amplitude control

    International Nuclear Information System (INIS)

    DeHaven, R.A.; Morris, C.L.; Johnson, R.; Davis, J.; O'Donnell, J.M.

    1992-01-01

    The analog controller for phase and amplitude control of a 402.5 MHz super conducting cavity is described in this paper. The cavity is a single cell with niobium explosively bonded to a copper cavity. It is used as an energy compressor for pions at the Clinton P. Anderson Meson Physics Facility (LAMPF). The controller maintains cavity frequency to within 4 degrees in phase of the LAMPF beam frequency. Field amplitude is maintained to within 2 percent. This control is accomplished at critical coupling (Q loaded of 1 x 10 9 ) with the use of only a 30 watt rf amplifier for accelerating fields of 6 MV/m. The design includes the use of piezoelectric crystals for fast resonance control. Three types of control, self excited VCO, and a reference frequency driven, were tried on this cavity and we present a comparison of their performance

  18. Periodic instantons and scattering amplitudes

    International Nuclear Information System (INIS)

    Khlebnikov, S.Yu.; Rubakov, V.A.; Tinyakov, P.G.

    1991-04-01

    We discuss the role of periodic euclidean solutions with two turning points and zero winding number (periodic instantons) in instanton induced processes below the sphaleron energy E sph . We find that the periodic instantons describe certain multiparticle scattering events leading to the transitions between topologically distinct vacua. Both the semiclassical amplitudes and inital and final states of these transitions are determined by the periodic instantons. Furthermore, the corresponding probabilities are maximal among all states of given energy. We show that at E ≤ E sph , the periodic instantons can be approximated by infinite chains of ordinary instantons and anti-instantons, and they naturally emerge as deformations of the zero energy instanton. In the framework of 2d abelian Higgs model and 4d electroweak theory we show, however, that there is not obvious relation between periodic instantons and two-particle scattering amplitudes. (orig.)

  19. Determination of the scattering amplitude

    International Nuclear Information System (INIS)

    Gangal, A.D.; Kupsch, J.

    1984-01-01

    The problem to determine the elastic scattering amplitude from the differential cross-section by the unitarity equation is reexamined. We prove that the solution is unique and can be determined by a convergent iteration if the parameter lambda=sin μ of Newton and Martin is bounded by lambda 2 approx.=0.86. The method is based on a fixed point theorem for holomorphic mappings in a complex Banach space. (orig.)

  20. Pulse amplitude modulated chlorophyll fluorometer

    Science.gov (United States)

    Greenbaum, Elias; Wu, Jie

    2015-12-29

    Chlorophyll fluorometry may be used for detecting toxins in a sample because of changes in micro algae. A portable lab on a chip ("LOAC") based chlorophyll fluorometer may be used for toxin detection and environmental monitoring. In particular, the system may include a microfluidic pulse amplitude modulated ("PAM") chlorophyll fluorometer. The LOAC PAM chlorophyll fluorometer may analyze microalgae and cyanobacteria that grow naturally in source drinking water.

  1. Semiclassical approach to fidelity amplitude

    International Nuclear Information System (INIS)

    García-Mata, Ignacio; Vallejos, Raúl O; Wisniacki, Diego A

    2011-01-01

    The fidelity amplitude (FA) is a quantity of paramount importance in echo-type experiments. We use semiclassical theory to study the average FA for quantum chaotic systems under external perturbation. We explain analytically two extreme cases: the random dynamics limit - attained approximately by strongly chaotic systems - and the random perturbation limit, which shows a Lyapunov decay. Numerical simulations help us to bridge the gap between both the extreme cases. (paper)

  2. FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.

    Directory of Open Access Journals (Sweden)

    Alexandra Rasnitsyn

    Full Text Available The neurodegenerative disease glaucoma is one of the leading causes of blindness in the world. Glaucoma is characterized by progressive visual field loss caused by retinal ganglion cell (RGC death. Both surgical glaucoma treatments and medications are available, however, they only halt glaucoma progression and are unable to reverse damage. Furthermore, many patients do not respond well to treatments. It is therefore important to better understand the mechanisms involved in glaucoma pathogenesis. Patients with Axenfeld-Rieger syndrome (ARS offer important insight into glaucoma progression. ARS patients are at 50% risk of developing early onset glaucoma and respond poorly to treatments, even when surgical treatments are combined with medications. Mutations in the transcription factor FOXC1 cause ARS. Alterations in FOXC1 levels cause ocular malformations and disrupt stress response in ocular tissues, thereby contributing to glaucoma progression. In this study, using biochemical and molecular techniques, we show that FOXC1 regulates the expression of RAB3GAP1, RAB3GAP2 and SNAP25, three genes with central roles in both exocytosis and endocytosis, responsible for extracellular trafficking. FOXC1 positively regulates RAB3GAP1 and RAB3GAP2, while either increase or decrease in FOXC1 levels beyond its normal range results in decreased SNAP25. In addition, we found that FOXC1 regulation of RAB3GAP1, RAB3GAP2 and SNAP25 affects secretion of Myocilin (MYOC, a protein associated with juvenile onset glaucoma and steroid-induced glaucoma. The present work reveals that FOXC1 is an important regulator of exocytosis and establishes a new link between FOXC1 and MYOC-associated glaucoma.

  3. Time-amplitude converter; Convertisseur temps-amplitude

    Energy Technology Data Exchange (ETDEWEB)

    Banner, M [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    It is normal in high energy physics to measure the time of flight of a particle in order to determine its mass. This can be done by the method which consists in transforming the time measurement into an analysis of amplitude, which is easier; a time-amplitude converter has therefore been built for this purpose. The apparatus here described uses a double grid control tube 6 BN 6 whose resolution time, as measured with a pulse generator, is 5 x 10{sup -11} s. The analysis of the response of a particle counter, made up of a scintillator and a photomultiplier, indicates that a time of resolution of 5 x 10{sup -10} s. can be obtained. A time of this order of magnitude is obtained experimentally with the converter. This converter has been used in the study of the time of flight of particles in a secondary beam of the accelerator Saturne. It has thus been possible to measure the energy spectrum of {pi}-mesons, of protons, and of deutons emitted from a polyethylene target bombarded by 1,4 and 2 GeV protons. (author) [French] Pour determiner la masse d'une particule, il est courant, en physique des hautes energies, de mesurer le temps de vol de cette particule. Cela peut etre fait par la methode qui consiste a transformer la mesure d'un temps en une analyse d'amplitude, plus aisee; aussi a-t-on, a cet effet, cree un convertisseur temps-amplitude. L'appareillage decrit dans cet article utilise un tube a double grille de commande 6 BN 6 dont le temps de resolution mesure avec un generateur d'impulsion est de 5.10{sup -11} s. L'analyse de la reponse d'un compteur de particules, constitue par un scintillateur et un photomultiplicateur, indique qu'un temps de resolution de 5.10{sup -10} s peut etre obtenu. Un temps de cet ordre est atteint experimentalement avec le convertisseur. Ce convertisseur a servi a l'etude du temps de vol des particules dans un faisceau secondaire de l'accelerateur Saturne. On a mesure ainsi le spectre d'energie des mesons {pi}, des protons, des deutons

  4. THE EFFECTS OF OXIDANT AIR POLLUTANTS ON SOYBEANS, SNAP BEANS AND POTATOES

    Science.gov (United States)

    During the past 5 years the impact of photochemical oxidants on soybeans and snap beans in Maryland and on potatoes in Virginia and Delaware was assessed with open-top chambers. The mean yields of four selected soybean varieties grown in open-top chambers with carbon-filtered air...

  5. Carbon dioxide (CO2) laser treatment of cutaneous papillomas in a common snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Raiti, Paul

    2008-06-01

    Carbon dioxide (CO2) laser was used to treat multiple cutaneous papillomas on an adult female common snapping turtle, Chelydra serpentina serpentina. A combination of excisional and ablative techniques provided excellent intraoperative visibility and postoperative results due to the laser's unique ability to incise and vaporize soft tissue.

  6. SNAP Participation in Preschool-Aged Children and Prevalence of Overweight and Obesity

    Science.gov (United States)

    Simmons, Shannon; Alexander, Jeffrey L.; Ewing, Helen; Whetzel, Stephanie

    2012-01-01

    Background: An increased prevalence of overweight and obesity for adults on government-funded nutrition assistance, such as the Supplemental Nutrition Assistance Program (SNAP), has been observed; however, this association among preschool-aged children is not well understood. Longitudinal research designs tracking changes in body mass…

  7. Surgical Treatment of Snapping Scapula Syndrome Due to Malunion of Rib Fractures.

    Science.gov (United States)

    Ten Duis, Kaj; IJpma, Frank F A

    2017-02-01

    This report describes a case of snapping scapula syndrome (SSS) caused by malunited rib fractures. Abrasion of the deformed ribs was performed with good results. SSS as a cause of shoulder pain after thoracic trauma has to be considered and can be treated by a surgical abrasion technique. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  8. Innovative, wearable snap connector technology for improved device networking in electronic garments

    Science.gov (United States)

    Kostrzewski, Andrew A.; Lee, Kang S.; Gans, Eric; Winterhalter, Carole A.; Jannson, Tomasz P.

    2007-04-01

    This paper discusses Physical Optics Corporation's (POC) wearable snap connector technology that provides for the transfer of data and power throughout an electronic garment (e-garment). These connectors resemble a standard garment button and can be mated blindly with only one hand. Fully compatible with military clothing, their application allows for the networking of multiple electronic devices and an intuitive method for adding/removing existing components from the system. The attached flexible cabling also permits the rugged snap connectors to be fed throughout the standard webbing found in military garments permitting placement in any location within the uniform. Variations of the snap electronics/geometry allow for integration with USB 2.0 devices, RF antennas, and are capable of transferring high bandwidth data streams such as the 221 Mbps required for VGA video. With the trend towards providing military officers with numerous electronic devices (i.e., heads up displays (HMD), GPS receiver, PDA, etc), POC's snap connector technology will greatly improve cable management resulting in a less cumbersome uniform. In addition, with electronic garments gaining widespread adoption in the commercial marketplace, POC's technology is finding applications in such areas as sporting good manufacturers and video game technology.

  9. Droplet snap-off in fluids with nematic liquid crystalline ordering

    International Nuclear Information System (INIS)

    Verhoeff, A A; Lekkerkerker, H N W

    2012-01-01

    We studied the snap-off of nematic liquid crystalline droplets originating from the Rayleigh-Taylor instability at the isotropic-nematic interface in suspensions of charged gibbsite in water and sterically stabilized gibbsite in bromotoluene. We found that droplet snap-off strongly depends on the director field structure inside the thinning neck, which is determined by the ratio of the splay elastic constant and the anchoring strength of the nematic phase to the droplet interface relative to the thickness of the thinning neck. If anchoring is weak, which is the case for aqueous gibbsite, this ratio is comparable to the thickness of the breaking thread. As a result, the thinning neck and pending drop have a uniform director field and droplet snap-off is determined by the viscous properties of the liquid crystal as well as by thermal fluctuations of the interface. On the other hand, in sterically stabilized gibbsite where anchoring is strong, this ratio is significantly smaller than the neck thickness. In this case, the neck has an escaped radial director field and the neck thinning is retarded close to snap-off due to a topological energy barrier involved in the separation of the droplet from the thread. (paper)

  10. 76 FR 35787 - Updated Trafficking Definition and Supplemental Nutrition Assistance Program (SNAP)-FDPIR Dual...

    Science.gov (United States)

    2011-06-20

    ...-Rulemaking Portal: Go to http://www.regulations.gov . Preferred method; follow the online instructions for... included in the record and will be made available to the public. Please be advised that the substance of... definition of trafficking in SNAP benefits is as follows: ``Trafficking means the buying or selling of...

  11. Amplitude modulation reflectometer for FTU

    International Nuclear Information System (INIS)

    Zerbini, M.; Buratti, P.; Centioli, C.; Amadeo, P.

    1995-06-01

    Amplitude modulation (AM) reflectometry is a modification of the classical frequency sweep technique which allows to perform unambiguous phase delay measurements. An eight-channel AM reflectometer has been realized for the measurement of density profiles on the FTU tokamak in the range. The characteristics of the instrument have been determined in extensive laboratory tests; particular attention has been devoted to the effect of interference with parasitic reflections. The reflectometer is now operating on FTU. Some examples of the first experimental data are discussed

  12. Superstring amplitudes and contact interactions

    International Nuclear Information System (INIS)

    Greensite, J.

    1987-08-01

    We show that scattering amplitudes computed from light-cone superstring field theory are divergent at tree level. The divergences can be eliminated, and supersymmetry restored, by the addition of certain counter terms to the light-cone Hamiltonian. These counter terms have the form of local contact interactions, whose existence we had previously deduced on grounds of vacuum stability, and closure of the super-Poincare algebra. The quartic contact interactions required in Type I and Type IIB superstring theories are constructed in detail. (orig.)

  13. Forward amplitude in pion deuteron

    International Nuclear Information System (INIS)

    Ferreira, E.M.; Munguia, G.A.P.; Rosa, L.P.; Thome, Z.D.

    1979-06-01

    The data on total cross section for πd scattering is analysed in terms of a single scattering calculation with Fermi motion dependence, in order to obtain a criterion to fix the value of the energy entering the two body meson nucleon amplitude. It is found that the prescription derived from the non-relativistic three body kinematics gives reasonable results. The introduction of a shift in the energy value, possibly representing nuclear binding effects, leads to a very good fitting of the data. The results are compared with those obtained in direct calculations of Faddeev equations and with the Brueckner model of fixed scatterers. (Author) [pt

  14. Examining the time dependence of DAMA's modulation amplitude

    Science.gov (United States)

    Kelso, Chris; Savage, Christopher; Sandick, Pearl; Freese, Katherine; Gondolo, Paolo

    2018-03-01

    If dark matter is composed of weakly interacting particles, Earth's orbital motion may induce a small annual variation in the rate at which these particles interact in a terrestrial detector. The DAMA collaboration has identified at a 9.3σ confidence level such an annual modulation in their event rate over two detector iterations, DAMA/NaI and DAMA/LIBRA, each with ˜ 7 years of observations. This data is well fit by a constant modulation amplitude for the two iterations of the experiment. We statistically examine the time dependence of the modulation amplitudes, which "by eye" appear to be decreasing with time in certain energy ranges. We perform a chi-squared goodness of fit test of the average modulation amplitudes measured by the two detector iterations which rejects the hypothesis of a consistent modulation amplitude at greater than 80, 96, and 99.6% for the 2-4, 2-5 and 2-6 keVee energy ranges, respectively. We also find that among the 14 annual cycles there are three ≳ 3σ departures from the average in our estimated data in the 5-6 keVee energy range. In addition, we examined several phenomenological models for the time dependence of the modulation amplitude. Using a maximum likelihood test, we find that descriptions of the modulation amplitude as decreasing with time are preferred over a constant modulation amplitude at anywhere between 1σ and 3σ , depending on the phenomenological model for the time dependence and the signal energy range considered. A time dependent modulation amplitude is not expected for a dark matter signal, at least for dark matter halo morphologies consistent with the DAMA signal. New data from DAMA/LIBRA-phase2 will certainly aid in determining whether any apparent time dependence is a real effect or a statistical fluctuation.

  15. 2-vertex Lorentzian spin foam amplitudes for dipole transitions

    Science.gov (United States)

    Sarno, Giorgio; Speziale, Simone; Stagno, Gabriele V.

    2018-04-01

    We compute transition amplitudes between two spin networks with dipole graphs, using the Lorentzian EPRL model with up to two (non-simplicial) vertices. We find power-law decreasing amplitudes in the large spin limit, decreasing faster as the complexity of the foam increases. There are no oscillations nor asymptotic Regge actions at the order considered, nonetheless the amplitudes still induce non-trivial correlations. Spin correlations between the two dipoles appear only when one internal face is present in the foam. We compute them within a mini-superspace description, finding positive correlations, decreasing in value with the Immirzi parameter. The paper also provides an explicit guide to computing Lorentzian amplitudes using the factorisation property of SL(2,C) Clebsch-Gordan coefficients in terms of SU(2) ones. We discuss some of the difficulties of non-simplicial foams, and provide a specific criterion to partially limit the proliferation of diagrams. We systematically compare the results with the simplified EPRLs model, much faster to evaluate, to learn evidence on when it provides reliable approximations of the full amplitudes. Finally, we comment on implications of our results for the physics of non-simplicial spin foams and their resummation.

  16. Concentration of Tobacco Advertisements at SNAP and WIC Stores, Philadelphia, Pennsylvania, 2012

    Science.gov (United States)

    Chilton, Mariana; Zhao, Qian-Wei; Szymkowiak, Dorota; Coffman, Ryan; Mallya, Giridhar

    2015-01-01

    Introduction Tobacco advertising is widespread in urban areas with racial/ethnic minority and low-income households that participate in nutrition assistance programs. Tobacco sales and advertising are linked to smoking behavior, which may complicate matters for low-income families struggling with disparate health risks relating to nutrition and chronic disease. We investigated the relationship between the amount and type of tobacco advertisements on tobacco outlets and the outlet type and location. Methods By using field visits and online images, we inspected all licensed tobacco retail outlets in Philadelphia (N = 4,639). Point pattern analyses were used to identify significant clustering of tobacco outlets and outlets with exterior tobacco advertisements. Logistic regression was used to analyze the relationship between the outlet’s acceptance of Supplemental Nutrition Assistance Program (SNAP) and Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and the presence of tobacco advertisements. Results Tobacco outlets with exterior tobacco advertisements were significantly clustered in several high-poverty areas. Controlling for racial/ethnic and income composition and land use, SNAP and WIC vendors were significantly more likely to have exterior (SNAP odds ratio [OR], 2.11; WIC OR, 1.59) and interior (SNAP OR, 3.43; WIC OR, 1.69) tobacco advertisements than other types of tobacco outlets. Conclusion Tobacco advertising is widespread at retail outlets, particularly in low-income and racial/ethnic minority neighborhoods. Policy makers may be able to mitigate the effects of this disparate exposure through tobacco retail licensing, local sign control rules, and SNAP and WIC authorization. PMID:25654220

  17. Reflective Polyethylene Mulch Reduces Mexican Bean Beetle (Coleoptera: Coccinellidae) Densities and Damage in Snap Beans.

    Science.gov (United States)

    Nottingham, L B; Kuhar, T P

    2016-08-01

    Mexican bean beetle, Epilachna varivestis Mulsant, is a serious pest of snap beans, Phaseolus vulgaris L., in the eastern United States. These beetles are intolerant to direct sunlight, explaining why individuals are typically found on the undersides of leaves and in the lower portion of the plant canopy. We hypothesized that snap beans grown on reflective, agricultural polyethylene (plastic mulch) would have fewer Mexican bean beetles and less injury than those grown on black plastic or bare soil. In 2014 and 2015, beans were seeded into beds of metallized, white, and black plastic, and bare soil, in field plots near Blacksburg, VA. Mexican bean beetle density, feeding injury, predatory arthropods, and snap bean yield were sampled. Reflected light intensity, temperature, and humidity were monitored using data loggers. Pyranometer readings showed that reflected light intensity was highest over metallized plastic and second highest over white plastic; black plastic and bare soil were similarly low. Temperature and humidity were unaffected by treatments. Significant reductions in Mexican bean beetle densities and feeding injury were observed in both metallized and white plastic plots compared to black plastic and bare soil, with metallized plastic having the fewest Mexican bean beetle life stages and injury. Predatory arthropod densities were not reduced by reflective plastic. Metallized plots produced the highest yields, followed by white. The results of this study suggest that growing snap beans on reflective plastic mulch can suppress the incidence and damage of Mexican bean beetle, and increase yield in snap beans. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Association of impulsivity and polymorphic microRNA-641 target sites in the SNAP-25 gene.

    Directory of Open Access Journals (Sweden)

    Nóra Németh

    Full Text Available Impulsivity is a personality trait of high impact and is connected with several types of maladaptive behavior and psychiatric diseases, such as attention deficit hyperactivity disorder, alcohol and drug abuse, as well as pathological gambling and mood disorders. Polymorphic variants of the SNAP-25 gene emerged as putative genetic components of impulsivity, as SNAP-25 protein plays an important role in the central nervous system, and its SNPs are associated with several psychiatric disorders. In this study we aimed to investigate if polymorphisms in the regulatory regions of the SNAP-25 gene are in association with normal variability of impulsivity. Genotypes and haplotypes of two polymorphisms in the promoter (rs6077690 and rs6039769 and two SNPs in the 3' UTR (rs3746544 and rs1051312 of the SNAP-25 gene were determined in a healthy Hungarian population (N = 901 using PCR-RFLP or real-time PCR in combination with sequence specific probes. Significant association was found between the T-T 3' UTR haplotype and impulsivity, whereas no association could be detected with genotypes or haplotypes of the promoter loci. According to sequence alignment, the polymorphisms in the 3' UTR of the gene alter the binding site of microRNA-641, which was analyzed by luciferase reporter system. It was observed that haplotypes altering one or two nucleotides in the binding site of the seed region of microRNA-641 significantly increased the amount of generated protein in vitro. These findings support the role of polymorphic SNAP-25 variants both at psychogenetic and molecular biological levels.

  19. Poor Dietary Guidelines Compliance among Low-Income Women Eligible for Supplemental Nutrition Assistance Program-Education (SNAP-Ed

    Directory of Open Access Journals (Sweden)

    Shinyoung Jun

    2018-03-01

    Full Text Available The Supplemental Nutrition Assistance Program-Education (SNAP-Ed program aims to improve nutritional intakes of low-income individuals (<185% poverty threshold. The objective of this study was to describe the compliance with Dietary Guidelines for Americans (DGA recommendations for fruits, vegetables, and whole grains among SNAP-Ed eligible (n = 3142 and ineligible (n = 3168 adult women (19–70 years nationwide and SNAP-Ed participating women in Indiana (n = 2623, using the NHANES 2007–2012 and Indiana SNAP-Ed survey data, respectively. Sensitivity analysis further stratified women by race/ethnicity and by current SNAP participation (<130% poverty threshold. Nationally, lower-income women were less likely to meet the fruit (21% vs. 25% and vegetable (11% vs. 19% guidelines than higher-income women, but did not differ on whole grains, which were ~5% regardless of income. The income differences in fruit and vegetable intakes were driven by non-Hispanic whites. Fewer SNAP-Ed-eligible U.S. women met fruit (21% vs. 55% and whole grain (4% vs. 18% but did not differ for vegetable recommendations (11% vs. 9% when compared to Indiana SNAP-Ed women. This same trend was observed among current SNAP participants. Different racial/ethnic group relationships with DGA compliance were found in Indiana compared to the nation. Nevertheless, most low-income women in the U.S. are at risk of not meeting DGA recommendations for fruits (79%, vegetables (89%, and whole grains (96%; SNAP-Ed participants in Indiana had higher compliance with DGA recommendations. Increased consumption of these three critical food groups would improve nutrient density, likely reduce calorie consumption by replacing high calorie choices, and improve fiber intakes.

  20. Covariant amplitudes in Polyakov string theory

    International Nuclear Information System (INIS)

    Aoyama, H.; Dhar, A.; Namazie, M.A.

    1986-01-01

    A manifestly Lorentz-covariant and reparametrization-invariant procedure for computing string amplitudes using Polyakov's formulation is described. Both bosonic and superstring theories are dealt with. The computation of string amplitudes is greatly facilitated by this formalism. (orig.)

  1. Grassmannian geometry of scattering amplitudes

    CERN Document Server

    Arkani-Hamed, Nima; Cachazo, Freddy; Goncharov, Alexander; Postnikov, Alexander; Trnka, Jaroslav

    2016-01-01

    Outlining a revolutionary reformulation of the foundations of perturbative quantum field theory, this book is a self-contained and authoritative analysis of the application of this new formulation to the case of planar, maximally supersymmetric Yang–Mills theory. The book begins by deriving connections between scattering amplitudes and Grassmannian geometry from first principles before introducing novel physical and mathematical ideas in a systematic manner accessible to both physicists and mathematicians. The principle players in this process are on-shell functions which are closely related to certain sub-strata of Grassmannian manifolds called positroids - in terms of which the classification of on-shell functions and their relations becomes combinatorially manifest. This is an essential introduction to the geometry and combinatorics of the positroid stratification of the Grassmannian and an ideal text for advanced students and researchers working in the areas of field theory, high energy physics, and the...

  2. Determination of backward pion nucleon scattering amplitudes

    International Nuclear Information System (INIS)

    Pietarinen, E.

    1978-04-01

    Backward C(sup(+-))πN amplitudes are determined from πN→Nπ and NantiN→2π differential cross sections in such a way that they are consistent with the analyticity properties and information of the unphysical ππ→NantiN amplitudes. Combining the result with forward C(sup(+-)) amplitudes positive and negative parity resonances are extracted. An error analysis of the amplitudes is performed. (author)

  3. Distal triceps injuries (including snapping triceps): A systematic review of the literature.

    Science.gov (United States)

    Shuttlewood, Kimberley; Beazley, James; Smith, Christopher D

    2017-06-18

    To review current literature on types of distal triceps injury and determine diagnosis and appropriate management. We performed a systematic review in PubMed, Cochrane and EMBASE using the terms distal triceps tears and snapping triceps on the 10 th January 2017. We excluded all animal, review, foreign language and repeat papers. We reviewed all papers for relevance and of the papers left we were able to establish the types of distal triceps injury, how these injuries are diagnosed and investigated and the types of management of these injuries including surgical. The results are then presented in a review paper format. Three hundred and seventy-nine papers were identified of which 65 were relevant to distal triceps injuries. After exclusion we had 47 appropriate papers. The papers highlighted 2 main distal triceps injuries: Distal triceps tears and snapping triceps. Triceps tear are more common in males than females occurring in the 4 th -5 th decade of life and often due to a direct trauma but are also strongly associated with weightlifting and American football. The tears are diagnosed by history and clinically with a palpable gap. Diagnosis can be confirmed with the use of ultrasound (US) and magnetic resonance imaging. Treatment depends on type of tear. Partial tears can be treated conservatively with bracing and physio whereas acute tears need repair either open or arthroscopic using suture anchor or bone tunnel techniques with similar success. Chronic tears often need augmenting with tendon allograft or autograft. Snapping triceps are also seen more in men than women but at a mean age of 32 years. They are characterized by a snapping sensation mostly medially and can be associated with ulna nerve subluxation and ulna nerve symptoms. US is the diagnostic modality of choice due to its dynamic nature and to differentiate between snapping triceps tendon or ulna nerve. Treatment is conservative initially with activity avoidance and if that fails surgical

  4. The physiology of overwintering in a turtle that occupies multiple habitats, the common snapping turtle (Chelydra serpentina).

    Science.gov (United States)

    Reese, Scott A; Jackson, Donald C; Ultsch, Gordon R

    2002-01-01

    Common snapping turtles, Chelydra serpentina (Linnaeus), were submerged in anoxic and normoxic water at 3 degrees C. Periodic blood samples were taken, and PO(2), PCO(2), pH, [Na(+)], [K(+)], [Cl(-)], total Ca, total Mg, [lactate], [glucose], hematocrit, and osmolality were measured; weight gain was determined; and plasma [HCO(3)(-)] was calculated. Submergence in normoxic water caused a decrease in PCO(2) from 10.8 to 6.9 mmHg after 125 d, partially compensating a slight increase in lactate and allowing the turtles to maintain a constant pH. Submergence in anoxic water caused a rapid increase in lactate from 1.8 to 168.1 mmol/L after 100 d. Associated with the increased lactate were decreases in pH from 8.057 to 7.132 and in [HCO(3)(-)] from 51.5 to 4.9 mmol/L and increases in total Ca from 2.0 to 36.6 mmol/L, in total Mg from 1.8 to 12.1 mmol/L, and in [K(+)] from 3.08 to 8.45 mmol/L. We suggest that C. serpentina is tolerant of anoxic submergence and therefore is able to exploit habitats unavailable to some other species in northern latitudes.

  5. Adjustments in cholinergic, adrenergic and purinergic control of cardiovascular function in snapping turtle embryos (Chelydra serpentina) incubated in chronic hypoxia.

    Science.gov (United States)

    Eme, John; Rhen, Turk; Crossley, Dane A

    2014-10-01

    Adenosine is an endogenous nucleoside that acts via G-protein coupled receptors. In vertebrates, arterial or venous adenosine injection causes a rapid and large bradycardia through atrioventricular node block, a response mediated by adenosine receptors that inhibit adenylate cyclase and decrease cyclic AMP concentration. Chronic developmental hypoxia has been shown to alter cardioregulatory mechanisms in reptile embryos, but adenosine's role in mediating these responses is not known. We incubated snapping turtle embryos under chronic normoxic (N21; 21 % O2) or chronic hypoxic conditions (H10; 10 % O2) beginning at 20 % of embryonic incubation. H10 embryos at 90 % of incubation were hypotensive relative to N21 embryos in both normoxic and hypoxic conditions. Hypoxia caused a hypotensive bradycardia in both N21 and H10 embryos during the initial 30 min of exposure; however, f H and P m both trended towards increasing during the subsequent 30 min, and H10 embryos were tachycardic relative to N21 embryos in hypoxia. Following serial ≥1 h exposure to normoxic and hypoxic conditions, a single injection of adenosine (1 mg kg(-1)) was given. N21 and H10 embryos responded to adenosine injection with a rapid and large hypotensive bradycardia in both normoxia and hypoxia. Gene expression for adenosine receptors were quantified in cardiac tissue, and Adora1 mRNA was the predominant receptor subtype with transcript levels 30-82-fold higher than Adora2A or Adora2B. At 70 % of incubation, H10 embryos had lower Adora1 and Adora2B expression compared to N21 embryos. Expression of Adora1 and Adora2B decreased in N21 embryos during development and did not differ from H10 embryos at 90 % of incubation. Similar to previous results in normoxia, H10 embryos in hypoxia were chronically tachycardic compared to N21 embryos before and after complete cholinergic and adrenergic blockade. Chronic hypoxia altered the development of normal cholinergic and adrenergic tone, as well as

  6. A Simple Snap Oscillator with Coexisting Attractors, Its Time-Delayed Form, Physical Realization, and Communication Designs

    Science.gov (United States)

    Rajagopal, Karthikeyan; Jafari, Sajad; Akgul, Akif; Karthikeyan, Anitha; Çiçek, Serdar; Shekofteh, Yasser

    2018-05-01

    In this paper, we report a novel chaotic snap oscillator with one nonlinear function. Dynamic analysis of the system shows the existence of bistability. To study the time delay effects on the proposed snap oscillator, we introduce multiple time delay in the fourth state equation. Investigation of dynamical properties of the time-delayed system shows that the snap oscillator exhibits the same multistable properties as the nondelayed system. The new multistable hyperjerk chaotic system has been tested in chaos shift keying and symmetric choc shift keying modulated communication designs for engineering applications. It has been determined that the symmetric chaos shift keying modulated communication system implemented with the new chaotic system is more successful than the chaos shift keying modulation for secure communication. Also, circuit implementation of the chaotic snap oscillator with tangent function is carried out showing its feasibility.

  7. Radial convection of finite ion temperature, high amplitude plasma blobs

    DEFF Research Database (Denmark)

    Wiesenberger, M.; Madsen, Jens; Kendl, Alexander

    2014-01-01

    We present results from simulations of seeded blob convection in the scrape-off-layer of magnetically confined fusion plasmas. We consistently incorporate high fluctuation amplitude levels and finite Larmor radius (FLR) effects using a fully nonlinear global gyrofluid model. This is in line......-field transport compared to blobs simulated with the local model. The maximal blob amplitude is significantly higher in the global simulations than in the local ones. When the ion temperature is comparable to the electron temperature, global blob simulations show a reduced blob coherence and a decreased cross...

  8. Neutron flux calculations for the Rossendorf research reactor in (hex)- and (hex,z)-geometry using SNAP-3D

    International Nuclear Information System (INIS)

    Koch, R.; Findeisen, A.

    1986-04-01

    The multigroup neutron diffusion theory code SNAP-3D has been used to perform time independent neutron flux and power calculations of the 10 MW Rossendorf research reactor of the type WWR-SM. The report describes these calculations, as well as the actual reactor configuration, some details of the code SNAP-3D, and two- and three-dimensional reactor models. For evaluating the calculations some flux values and control rod worths have been compared with those of measurements. (author)

  9. Toward the topology design of mechanisms that exhibit snap-through behavior

    DEFF Research Database (Denmark)

    Burns, T. E.; Sigmund, Ole

    2004-01-01

    Topology optimization has proven to be a powerful method for the conceptual design of structures and mechanisms. In previously published work, we concentrated on the development of numerical methods that accommodate the finite deformation and incorporated these analyses into the topology...... optimization. We demonstrated by relatively straightforward transversely loaded clamped-clamped beam examples that topology optimization can be used to design structures that experience snap-through behavior. Here, we focus our attention on the design problem formulation where the goal is to develop a general...... approach for the design of mechanisms that experience more complex snap-through behavior. A multiphase design strategy is outlined, numerous significant challenges to this complex design process are discussed, and several examples are presented that demonstrate progress toward this goal. (C) 2004 Elsevier...

  10. Development of a mercury electromagnetic centrifugal pump for the SNAP-8 refractory boiler development program

    Science.gov (United States)

    Fuller, R. A.; Schnacke, A. W.

    1974-01-01

    An electromagnetic pump, in which pressure is developed in mercury because of the interaction of the magnetic field and current which flows as a result of the voltage induced in the mercury contained in the pump duct, was developed for the SNAP-8 refractory boiler test facility. Pump performance results are presented for ten duct configurations and two stator sizes. These test results were used to design and fabricate a pump which met the SNAP-8 criteria of 530 psi developed pressure at 12,500 lb/hr. The pump operated continuously for over 13,000 hours without failure or performance degradation. Included in this report are descriptions of the experimental equipment, measurement techniques, all experimental data, and an analysis of the electrical losses in the pump.

  11. ENGAGING ELEMENTARY AND MIDDLE SCHOOL STUDENTS IN ROBOTICS THROUGH HUMMINGBIRD KIT WITH SNAP! VISUAL PROGRAMMING LANGUAGE

    OpenAIRE

    Anna Newley; Hasan Deniz; Erdogan Kaya; Ezgi Yesilyurt

    2016-01-01

    The purpose of this paper is to describe how Hummingbird robotics kit with Snap! programing language was used to introduce basics of robotics to elementary and middle school students. Each student in the robotics program built a robot. The robot building process was open ended. Any specific robotics challenge was not provided to the students. Students’ knowledge about robots and programming language were measured through pre, post, and delayed posttests. Results indicated that students improv...

  12. Niobium tunnel junction fabrication using e-gun evaporation and SNAP

    Science.gov (United States)

    Kortlandt, J.; van der Zant, H. S. J.; Schellingerhout, A. J. G.; Mooij, J. E.

    1990-11-01

    We have fabricated high quality small area Nb-Al-Al 2O 3-Nb junctions with SNAP, making use of e-beam evaporation in a 10 -5 Pa diffusion pumped vacuum system. Nominal dimensions of the junctions are 8x8, 4x4 and 2x2 μm 2. We obtain typical current densities of 5-6 × 10 +2A/cm 2 and (critical current) x (subgap resistance) products of 40 mV.

  13. SNAP Participants? Eating Patterns over the Benefit Month: A Time Use Perspective

    OpenAIRE

    Hamrick, Karen S.; Andrews, Margaret

    2016-01-01

    Individuals receiving monthly benefits through the U.S. Supplemental Nutrition Assistance Program (SNAP) often fall short of food at the end of the month and some report feelings of hunger. To investigate this situation, we used time diaries from the 2006-08 American Time Use Survey and Eating & Health Module to identify the timing of days where respondents reported no eating occurrences. Analysis includes descriptive statistics, a logit model, and a simulated benefit month. We found that SNA...

  14. SNAP dendrimers: multivalent protein display on dendrimer-like DNA for directed evolution.

    Science.gov (United States)

    Kaltenbach, Miriam; Stein, Viktor; Hollfelder, Florian

    2011-09-19

    Display systems connect a protein with the DNA encoding it. Such systems (e.g., phage or ribosome display) have found widespread application in the directed evolution of protein binders and constitute a key element of the biotechnological toolkit. In this proof-of-concept study we describe the construction of a system that allows the display of multiple copies of a protein of interest in order to take advantage of avidity effects during affinity panning. To this end, dendrimer-like DNA is used as a scaffold with docking points that can join the coding DNA with multiple protein copies. Each DNA construct is compartmentalised in water-in-oil emulsion droplets. The corresponding protein is expressed, in vitro, inside the droplets as a SNAP-tag fusion. The covalent bond between DNA and the SNAP-tag is created by reaction with dendrimer-bound benzylguanine (BG). The ability to form dendrimer-like DNA straightforwardly from oligonucleotides bearing BG allowed the comparison of a series of templates differing in size, valency and position of BG. In model selections the most efficient constructs show recoveries of up to 0.86 % and up to 400-fold enrichments. The comparison of mono- and multivalent constructs suggests that the avidity effect enhances enrichment by up to fivefold and recovery by up to 25-fold. Our data establish a multivalent format for SNAP-display based on dendrimer-like DNA as the first in vitro display system with defined tailor-made valencies and explore a new application for DNA nanostructures. These data suggest that multivalent SNAP dendrimers have the potential to facilitate the selection of protein binders especially during early rounds of directed evolution, allowing a larger diversity of candidate binders to be recovered. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. On using the dynamic snap-through motion of MEMS initially curved microbeams for filtering applications

    KAUST Repository

    Ouakad, Hassen M.; Younis, Mohammad I.

    2014-01-01

    Numerical and experimental investigations of the dynamics of micromachined shallow arches (initially curved microbeams) and the possibility of using their dynamic snap-through motion for filtering purposes are presented. The considered MEMS arches are actuated by a DC electrostatic load along with an AC harmonic load. Their dynamics is examined numerically using a Galerkin-based reduced-order model when excited near both their first and third natural frequencies. Several simulation results are presented demonstrating interesting jumps and dynamic snap-through behavior of the MEMS arches and their attractive features for uses as band-pass filters, such as their sharp roll-off from pass-bands to stop-bands and their flat response. Experimental work is conducted to test arches realized of curved polysilicon microbeams when excited by DC and AC loads. Experimental data of the micromachined curved beams are shown for the softening and hardening behavior near the first and third natural frequencies, respectively, as well as dynamic snap-through motion. © 2013 Elsevier Ltd.

  16. Morphological study on the olfactory systems of the snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Nakamuta, Nobuaki; Nakamuta, Shoko; Kato, Hideaki; Yamamoto, Yoshio

    2016-06-01

    In this study, the olfactory system of a semi-aquatic turtle, the snapping turtle, has been morphologically investigated by electron microscopy, immunohistochemistry, and lectin histochemistry. The nasal cavity of snapping turtle was divided into the upper and lower chambers, lined by the sensory epithelium containing ciliated and non-ciliated olfactory receptor neurons, respectively. Each neuron expressed both Gαolf, the α-subunit of G-proteins coupling to the odorant receptors, and Gαo, the α-subunit of G-proteins coupling to the type 2 vomeronasal receptors. The axons originating from the upper chamber epithelium projected to the ventral part of the olfactory bulb, while those from the lower chamber epithelium to the dorsal part of the olfactory bulb. Despite the identical expression of G-protein α-subunits in the olfactory receptor neurons, these two projections were clearly distinguished from each other by the differential expression of glycoconjugates. In conclusion, these data indicate the presence of two types of olfactory systems in the snapping turtle. Topographic arrangement of the upper and lower chambers and lack of the associated glands in the lower chamber epithelium suggest their possible involvement in the detection of odorants: upper chamber epithelium in the air and the lower chamber epithelium in the water. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Study of an integral field spectrograph for the SNAP satellite. Prototype, simulation and performances

    International Nuclear Information System (INIS)

    Aumeunier, Marie-Helene

    2007-01-01

    The SNAP (Supernovae/Acceleration Probe) project plans to measure very precisely the cosmological parameters and to determine the nature of dark energy by observations of type Ia supernovae and weak lensing. The SNAP instrument consists in a 2-meter telescope with a one square-degree imager and a spectrograph in the visible and infrared range. A dedicated optimized integral field spectrograph based on an imager slicer technology has been developed. To test and validate the performances, two approaches have been developed: a complete simulation of the complete instrument at the pixel level and the manufacturing and test of a spectrograph prototype operating at room temperature and in cryogenic environment. In this thesis we will test the optical and functional performances of the SNAP spectrograph: especially diffraction losses, stray-light and spectro-photometric calibration. We present an original approach for the spectro-photometric calibration adapted for the slicer and the optical performances resulting from the first measurement campaign in the visible range. (author) [fr

  18. Integrative demographic modeling reveals population level impacts of PCB toxicity to juvenile snapping turtles

    International Nuclear Information System (INIS)

    Salice, Christopher J.; Rowe, Christopher L.; Eisenreich, Karen M.

    2014-01-01

    A significant challenge in ecotoxicology and risk assessment lies in placing observed contaminant effects in a meaningful ecological context. Polychlorinated biphenyls (PCBs) have been shown to affect juvenile snapping turtle survival and growth but the ecological significance of these effects is difficult to discern without a formal, population-level assessment. We used a demographic matrix model to explore the potential population-level effects of PCBs on turtles. Our model showed that effects of PCBs on juvenile survival, growth and size at hatching could translate to negative effects at the population level despite the fact that these life cycle components do not typically contribute strongly to population level processes. This research points to the utility of using integrative demographic modeling approaches to better understand contaminant effects in wildlife. The results indicate that population-level effects are only evident after several years, suggesting that for long-lived species, detecting adverse contaminant effects could prove challenging. -- Highlights: • Previous studies have shown the PCBs can impact juvenile snapping turtles. • We used a demographic model of turtles to evaluate population-level PCB effects. • PCB effects on turtles may translate to negative population responses. • Long-term monitoring is needed to detect contaminant effects on natural turtle populations. • Demographic models can improve our understanding contaminant ecotoxicity. -- A demographic model was used to show that PCB induced effects on young snapping turtles can result in adverse effects at the population level

  19. On expansion of scattering amplitude at large momentum transfers

    International Nuclear Information System (INIS)

    Edneral, V.F.; Troshin, S.M.; Tyurin, N.E.

    1979-01-01

    The aim of the paper is to construct an iterative approximation for hadronic scattering amplitude and to search for the related small parameters. The expansion of the amplitude is obtained. A series is derived where the role of the small parameter is played by the quantity dependent on the momentum transfer. The appearance of the small parameter is directly related to the growth of total cross section. For the case g 2 not equal to 0 in the framework of the strong interaction theory model, based on the solution of three-domensional dynamical equation an expression is obtained for scattering amplitude in the form of a series over the quantity decreasing with the growth of momentum transfer

  20. On the singularities of massive superstring amplitudes

    International Nuclear Information System (INIS)

    Foda, O.

    1987-01-01

    Superstring one-loop amplitudes with massive external states are shown to be in general ill-defined due to internal on-shell propagators. However, we argue that since any massive string state (in the uncompactified theory) has a finite lifetime to decay into massless particles, such amplitudes are not terms in the perturbative expansion of physical S-matrix elements: These can be defined only with massless external states. Consistent massive amplitudes repuire an off-shell formalism. (orig.)

  1. On the singularities of massive superstring amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Foda, O.

    1987-06-04

    Superstring one-loop amplitudes with massive external states are shown to be in general ill-defined due to internal on-shell propagators. However, we argue that since any massive string state (in the uncompactified theory) has a finite lifetime to decay into massless particles, such amplitudes are not terms in the perturbative expansion of physical S-matrix elements: These can be defined only with massless external states. Consistent massive amplitudes repuire an off-shell formalism.

  2. New relations for graviton-matter amplitudes

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    I report on recent progress in finding compact expressions for scattering amplitudes involving gravitons and gluons as well as massive scalar and fermionic matter particles. At tree level the single graviton emission amplitudes may be expressed as linear combination of purely non-gravitational ones. At the one-loop level recent results on all four point Einstein-Yang-Mills amplitudes with at most one opposite helicity state using unitarity methods are reported. 

  3. Analytical properties of multiple production amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Medvedev, B V; Pavlov, V P; Polivanov, M K; Sukhanov, A D [Gosudarstvennyj Komitet po Ispol' zovaniyu Atomnoj Ehnergii SSSR, Moscow. Inst. Teoreticheskoj i Ehksperimental' noj Fiziki; AN SSSR, Moscow. Matematicheskij Inst.)

    1984-05-01

    Local analytical properties of amplitudes 2..-->..3 and 2..-->..4 are studied. The amplitudes are shown to be analytical functions of total and partial energies at fixed momentum transfers in the neighbourhood of any physical point on the energy shell 14 (for the 2..-->..3 case) and 242 (for the 2..-->..4 case) boundary values are expressed through the amplitudes of real processes.

  4. GSC4813-0981 = V921 Mon, a new low-amplitude δ Scuti star with variable amplitude

    Science.gov (United States)

    Galeev, A.; Bikmaev, I.; Shimansky, V.; Deminova, N.

    2014-11-01

    GSC 4813-0981 = V921 Mon is a low-amplitude δ Scuti-type variable with an amplitude of 0.018^m-0.027^m in different bands and a period of 48.5 minutes. The fundamental parameters of the atmosphere and physical characteristics, determined from medium-resolution spectra, are: T_{eff}=8700 K, log g=3.95 dex, [M/H]=0, M=1.7 M_{⊙}, R=2.3 R_{⊙}. We performed a long-term analysis of the variations using a ten-year data set of CCD observations (2003-2013) acquired in BVR with the 1.5-m Russian-Turkish telescope (RTT150, TUBITAK National Observatory). A preliminary result is that the amplitude of the variability changes; it was decreasing during 2003-2008, but is now increasing.

  5. DVCS amplitude with kinematical twist-3 terms

    International Nuclear Information System (INIS)

    Radyushkin, A.V.; Weiss, C.

    2000-01-01

    The authors compute the amplitude of deeply virtual Compton scattering (DVCS) using the calculus of QCD string operators in coordinate representation. To restore the electromagnetic gauge invariance (transversality) of the twist-2 amplitude they include the operators of twist-3 which appear as total derivatives of twist-2 operators. The results are equivalent to a Wandzura-Wilczek approximation for twist-3 skewed parton distributions. They find that this approximation gives a finite result for the amplitude of a longitudinally polarized virtual photon, while the amplitude for transverse polarization is divergent, i.e., factorization breaks down in this term

  6. Amplitude structure of off-shell processes

    International Nuclear Information System (INIS)

    Fearing, H.W.; Goldstein, G.R.; Moravcsik, M.J.

    1984-01-01

    The structure of M matrices, or scattering amplitudes, and of potentials for off-shell processes is discussed with the objective of determining how one can obtain information on off-shell amplitudes of a process in terms of the physical observables of a larger process in which the first process is embedded. The procedure found is inevitably model dependent, but within a particular model for embedding, a determination of the physically measurable amplitudes of the larger process is able to yield a determination of the off-shell amplitudes of the embedded process

  7. Plasticity of cardiovascular function in snapping turtle embryos (Chelydra serpentina): chronic hypoxia alters autonomic regulation and gene expression.

    Science.gov (United States)

    Eme, John; Rhen, Turk; Tate, Kevin B; Gruchalla, Kathryn; Kohl, Zachary F; Slay, Christopher E; Crossley, Dane A

    2013-06-01

    Reptile embryos tolerate large decreases in the concentration of ambient oxygen. However, we do not fully understand the mechanisms that underlie embryonic cardiovascular short- or long-term responses to hypoxia in most species. We therefore measured cardiac growth and function in snapping turtle embryos incubated under normoxic (N21; 21% O₂) or chronic hypoxic conditions (H10; 10% O₂). We determined heart rate (fH) and mean arterial pressure (Pm) in acute normoxic (21% O₂) and acute hypoxic (10% O₂) conditions, as well as embryonic responses to cholinergic, adrenergic, and ganglionic pharmacological blockade. Compared with N21 embryos, chronic H10 embryos had smaller bodies and relatively larger hearts and were hypotensive, tachycardic, and following autonomic neural blockade showed reduced intrinsic fH at 90% of incubation. Unlike other reptile embryos, cholinergic and ganglionic receptor blockade both increased fH. β-Adrenergic receptor blockade with propranolol decreased fH, and α-adrenergic blockade with phentolamine decreased Pm. We also measured cardiac mRNA expression. Cholinergic tone was reduced in H10 embryos, but cholinergic receptor (Chrm2) mRNA levels were unchanged. However, expression of adrenergic receptor mRNA (Adrb1, Adra1a, Adra2c) and growth factor mRNA (Igf1, Igf2, Igf2r, Pdgfb) was lowered in H10 embryos. Hypoxia altered the balance between cholinergic receptors, α-adrenoreceptor and β-adrenoreceptor function, which was reflected in altered intrinsic fH and adrenergic receptor mRNA levels. This is the first study to link gene expression with morphological and cardioregulatory plasticity in a developing reptile embryo.

  8. A SNAP-tagged derivative of HIV-1--a versatile tool to study virus-cell interactions.

    Directory of Open Access Journals (Sweden)

    Manon Eckhardt

    Full Text Available Fluorescently labeled human immunodeficiency virus (HIV derivatives, combined with the use of advanced fluorescence microscopy techniques, allow the direct visualization of dynamic events and individual steps in the viral life cycle. HIV proteins tagged with fluorescent proteins (FPs have been successfully used for live-cell imaging analyses of HIV-cell interactions. However, FPs display limitations with respect to their physicochemical properties, and their maturation kinetics. Furthermore, several independent FP-tagged constructs have to be cloned and characterized in order to obtain spectral variations suitable for multi-color imaging setups. In contrast, the so-called SNAP-tag represents a genetically encoded non-fluorescent tag which mediates specific covalent coupling to fluorescent substrate molecules in a self-labeling reaction. Fusion of the SNAP-tag to the protein of interest allows specific labeling of the fusion protein with a variety of synthetic dyes, thereby offering enhanced flexibility for fluorescence imaging approaches.Here we describe the construction and characterization of the HIV derivative HIV(SNAP, which carries the SNAP-tag as an additional domain within the viral structural polyprotein Gag. Introduction of the tag close to the C-terminus of the matrix domain of Gag did not interfere with particle assembly, release or proteolytic virus maturation. The modified virions were infectious and could be propagated in tissue culture, albeit with reduced replication capacity. Insertion of the SNAP domain within Gag allowed specific staining of the viral polyprotein in the context of virus producing cells using a SNAP reactive dye as well as the visualization of individual virions and viral budding sites by stochastic optical reconstruction microscopy. Thus, HIV(SNAP represents a versatile tool which expands the possibilities for the analysis of HIV-cell interactions using live cell imaging and sub-diffraction fluorescence

  9. Antioxidant and Hypolipidaemic Effect of Raw Green Snap (Phaseolus vulgaris) on Aged Male Rats Exposed to gamma Irradiation

    International Nuclear Information System (INIS)

    Abed EI-Gawad, E.I.; Aiad, S.K.

    2008-01-01

    This Study was established to assess the effect of supplemental dietary raw green snap (Phaseolus vulgaris) for three months to overcome gamma-irradiation induced alterations on some oxidant/ antioxidant parameters (Fe 3+ , Cu 2+ , total iron, ferritin, transferrin and ceruloplasmin) and the hyper lipidemic state (triglycerides, cholesterol, high- and low density lipoprotein (HDL-c and LDL-c) in aged male rats. Raw green snap is an indigenous plant used in Unani and Ayurvedic medicine in India. The study also aimed to estimate the effect of dietary raw green snap on general health through the follow up of body weight and mortality during the course of supplementation. Thirty-two aged male rats (24 months, 370-375 g) were divided equally into four groups. 1- Control group, the animals fed on a balanced diet for 3 months. 2- Supplemented group, the animals balanced diet was supplemented with raw green snap (70 g / kg body wt/ day) for 3 months. 3- Irradiated group, the animals fed on a balanced diet for 3 months were then exposed to whole body y-radiation at a dose level of 4 Gy. 4-Supplemented-irradiated group, the animals' balanced diet was supplemented with raw green snap (70 g/ kg/ day) for three months and then exposed to whole body gamma irradiation at a dose level of 4 Gy. The blood samples were taken from orbital venous plexuses after 48 h of stopping green snap supplementation (supplemented group) or after irradiation (irradiated and supplemented gamma-irradiated groups). The results obtained showed reduction in the body wt in green snap supplemented group which increased gradually concomitant with occurrence of animal mortality on week 7 reaching II) maximal values (-32.79 and 33.33 %) respectively, on week 12 of supplementation. Also, the supplemented group showed non significant changes in tested parameters although the level of total iron and triglycerides recorded noticeable changes as compared with controls

  10. Hadronic processes with large transfer momenta and quark counting rules in multiparticle dual amplitude

    International Nuclear Information System (INIS)

    Akkelin, S.V.; Kobylinskij, N.A.; Martynov, E.S.

    1989-01-01

    A dual N-particle amplitude satisfying the quark counting rules for the processes with large transfer momenta is constructed. The multiparticle channels are shown to give an essential contribution to the amplitude decreasing power in a hard kinematic limit. 19 refs.; 9 figs

  11. Automation of loop amplitudes in numerical approach

    International Nuclear Information System (INIS)

    Fujimoto, J.; Ishikawa, T.; Shimizu, Y.; Kato, K.; Nakazawa, N.; Kaneko, T.

    1997-01-01

    An automatic calculating system GRACE-L1 of one-loop Feynman amplitude is reviewed. This system can be applied to 2 to 2-body one-loop processes. A sample calculation of 2 to 3-body one-loop amplitudes is also presented. (orig.)

  12. On the singularities of massive superstring amplitudes

    NARCIS (Netherlands)

    Foda, O.

    1987-01-01

    Superstring one-loop amplitudes with massive external states are shown to be in general ill-defined due to internal on-shell propagators. However, we argue that since any massive string state (in the uncompactified theory) has a finite lifetime to decay into massless particles, such amplitudes are

  13. Scattering Amplitudes via Algebraic Geometry Methods

    DEFF Research Database (Denmark)

    Søgaard, Mads

    Feynman diagrams. The study of multiloop scattering amplitudes is crucial for the new era of precision phenomenology at the Large Hadron Collider (LHC) at CERN. Loop-level scattering amplitudes can be reduced to a basis of linearly independent integrals whose coefficients are extracted from generalized...

  14. Helicity amplitudes for matter-coupled gravity

    International Nuclear Information System (INIS)

    Aldrovandi, R.; Novaes, S.F.; Spehler, D.

    1992-07-01

    The Weyl-van der Waerden spinor formalism is applied to the evaluation of helicity invariant amplitudes in the framework of linearized gravitation. The graviton couplings to spin-0, 1 - 2 , 1, and 3 - 2 particles are given, and, to exhibit the reach of this method, the helicity amplitudes for the process electron + positron → photon + graviton are obtained. (author)

  15. New relations for gauge-theory amplitudes

    International Nuclear Information System (INIS)

    Bern, Z.; Carrasco, J. J. M.; Johansson, H.

    2008-01-01

    We present an identity satisfied by the kinematic factors of diagrams describing the tree amplitudes of massless gauge theories. This identity is a kinematic analog of the Jacobi identity for color factors. Using this we find new relations between color-ordered partial amplitudes. We discuss applications to multiloop calculations via the unitarity method. In particular, we illustrate the relations between different contributions to a two-loop four-point QCD amplitude. We also use this identity to reorganize gravity tree amplitudes diagram by diagram, offering new insight into the structure of the Kawai-Lewellen-Tye (KLT) relations between gauge and gravity tree amplitudes. This insight leads to similar but novel relations. We expect this to be helpful in higher-loop studies of the ultraviolet properties of gravity theories.

  16. Gravothermal catastrophe of finite amplitude

    Energy Technology Data Exchange (ETDEWEB)

    Hachisu, I; Sugimoto, D [Tokyo Univ. (Japan). Coll. of General Education; Nakada, Y; Nomoto, K

    1978-08-01

    Development of the gravothermal catastrophe is followed numerically for self-gravitating gas system enclosed by an adiabatic wall, which is isothermal in the initial state. It is found that the final fate of the catastrophe is in two ways depending on the initial perturbations. When the initial perturbation produces a temperature distribution decreasing outward, the contraction proceeds in the central region and the central density increases unlimitedly, as the heat flows outward. When the initial temperature distribution is increasing outward, on the other hand, the central region expands as the heat flows into the central region. Then the density contrast is reduced and finally the system reaches another isothermal configuration with the same energy but with a lower density contrast and a higher entropy. This final configuration is gravothermally stable and may be called a thermal system. In the former case of the unlimited contraction, the final density profile is determined essentially by the density and temperature dependence of the heat conductivity. In the case of a system under the force of the inverse square law, the final density distribution is well approximated by a power law so that the mass contained in the condensed core is relatively small. A possibility of formation of a black hole in stellar systems is also discussed.

  17. Gravothermal catastrophe of finite amplitude

    International Nuclear Information System (INIS)

    Hachisu, Izumi; Sugimoto, Daiichiro; Nakada, Yoshikazu; Nomoto, Ken-ichi.

    1978-01-01

    Development of the gravothermal catastrophe is followed numerically for self-gravitating gas system enclosed by an adiabatic wall, which is isothermal in the initial state. It is found that the final fate of the catastrophe is in two ways depending on the initial perturbations. When the initial perturbation produces a temperature distribution decreasing outward, the contraction proceeds in the central region and the central density increases unlimitedly, as the heat flows outward. When the initial temperature distribution is increasing outward, on the other hand, the central region expands as the heat flows into the central region. Then the density contrast is reduced and finally the system reaches another isothermal configuration with the same energy but with a lower density contrast and a higher entropy. This final configuration is gravothermally stable and may be called a thermal system. In the former case of the unlimited contraction, the final density profile is determined essentially by the density and temperature dependence of the heat conductivity. In the case of a system under the force of the inverse square law, the final density distribution is well approximated by a power law so that the mass contained in the condensed core is relatively small. A possibility of formation of a black hole in stellar systems is also discussed. (author)

  18. Mercury concentrations in snapping turtles (Chelydra serpentina) correlate with environmental and landscape characteristics.

    Science.gov (United States)

    Turnquist, Madeline A; Driscoll, Charles T; Schulz, Kimberly L; Schlaepfer, Martin A

    2011-10-01

    Mercury (Hg) deposited onto the landscape can be transformed into methylmercury (MeHg), a neurotoxin that bioaccumulates up the aquatic food chain. Here, we report on Hg concentrations in snapping turtles (Chelydra serpentina) across New York State, USA. The objectives of this study were to: (1) test which landscape, water, and biometric characteristics correlate with total Hg (THg) concentrations in snapping turtles; and (2) determine whether soft tissue THg concentrations correlate with scute (shell) concentrations. Forty-eight turtles were sampled non-lethally from ten lakes and wetlands across New York to observe patterns under a range of ecosystem variables and water chemistry conditions. THg concentrations ranged from 0.041 to 1.50 μg/g and 0.47 to 7.43 μg/g wet weight of muscle tissue and shell, respectively. The vast majority of mercury (~94%) was in the MeHg form. Sixty-one percent of turtle muscle samples exceeded U.S. Environmental Protection Agency (U.S. EPA) consumption advisory limit of 0.3 μg Hg/g for fish. Muscle THg concentrations were significantly correlated with sulfate in water and the maximum elevation of the watershed. Shell THg concentrations were significantly correlated with the acid neutralizing capacity (ANC) of water, the maximum elevation of the watershed, the percent open water in the watershed, the lake to watershed size, and various forms of atmospheric Hg deposition. Thus, our results demonstrate that THg concentrations in snapping turtles are spatially variable, frequently exceed advisory limits, and are significantly correlated with several landscape and water characteristics.

  19. Oviductal morphology in relation to hormonal levels in the snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Alkindi, A Y A; Mahmoud, I Y; Woller, M J; Plude, J L

    2006-02-01

    Microscopic and in situ visual observations were used to relate circulating hormone levels to morphological changes in the oviduct of the snapping turtle Chelydra serpentina throughout the ovarian cycle. Increase in levels of progesterone (P), estradiol (E2) and testosterone (T) levels coincide with an increase in number and growth of endometrial glands, luminal epithelial cells and secretory droplets throughout the oviduct. Testosterone and estradiol levels rose significantly (P < 0.05) after the May-June period and remained high throughout the rest of the summer. Progesterone levels remained stable throughout the summer, with a brief decline in July due to luteolysis. Hormonal values declined significantly (P < 0.001) at the end of the ovarian cycle in the fall. In situ visual observation of fresh oviducts at different stages of gravidity in recently ovulated turtles revealed that proteinaceous like components from the endometrial glands were released into the lumen to form fibers. The morphological features of the oviduct remained active throughout the summer months even though the snapping turtle is a monoclutch species which deposits all the eggs in late-May to mid-June. The high steroid levels correlate with and may be responsible for the secretory activity present throughout the summer and their decline correlates with change to low secretory activity in the fall. Calcium deposition accompanied by morphological changes in luminal cells are suggestive of secretory activity. In the egg-bearing turtles, uterine Ca2+ concentrations measured by flame atomic absorption spectrophotometry revealed significantly higher Ca2+ concentrations (P < 0.001) in eggs with soft shell than eggs without shell. There was a significant increase in calcium granules and proteinaceous fibers in luminal surface of the uterus during the period of eggshelling. This supports the fact that in the snapping turtle like in other reptiles, eggshelling process occurs in the uterus.

  20. Production components and yield of bushing snap bean in conventional and organic production systems

    Directory of Open Access Journals (Sweden)

    Guilherme Renato Gomes

    2017-10-01

    Full Text Available Production systems influence crops differently, mainly in terms of yield. However, there are few studies that have evaluated different bushing snap bean genotypes in different systems. Thus, this study aimed to evaluate the production components and yield of bushing snap beans in conventional and organic production systems. The experimental design was a randomized complete block, in a factorial 6 × 2 arrangement, corresponding to six genotypes and two production systems, with three replications. The genotypes Isla Manteiga Baixo®, Isla Macarrão Baixo®, Feltrin Vicenza Amarelo Baixo®, and Feltrin Macarrão Napoli®, UEL 1, and UEL 2 were submitted to the following determinations: days to flowering; plant height; medium number of pods per plant; average pod mass, length, and diameter; and yield of commercial pods. A joint analysis of variance was conducted by applying the F test, with mean comparison performed using the Tukey’s test (p < 0.05. Anthesis of the genotypes Feltrin Vicenza Amarelo Baixo, UEL 2, Isla Macarrão Baixo, and Feltrin Macarrão Napoli is anticipated in the conventional production system. The genotype UEL 2 shows higher precocity in anthesis within the conventional system. The genotypes Isla Manteiga Baixo and UEL 1 produce more pods per plant in the conventional system. In the organic system, the genotype Feltrin Macarrão Napoli produces double the number of pods per plant compared with Isla Manteiga Baixo. The organic system leads to greater plant height and average mass, length, and diameter of pods in relation to the conventional system. The commercial pod yield of bushing snap bean is not altered by differences in the production system or genotype.

  1. An efficacy trial of brief lifestyle intervention delivered by generalist community nurses (CN SNAP trial

    Directory of Open Access Journals (Sweden)

    Fanaian Mahnaz

    2010-02-01

    Full Text Available Abstract Background Lifestyle risk factors, in particular smoking, nutrition, alcohol consumption and physical inactivity (SNAP are the main behavioural risk factors for chronic disease. Primary health care (PHC has been shown to be an effective setting to address lifestyle risk factors at the individual level. However much of the focus of research to date has been in general practice. Relatively little attention has been paid to the role of nurses working in the PHC setting. Community health nurses are well placed to provide lifestyle intervention as they often see clients in their own homes over an extended period of time, providing the opportunity to offer intervention and enhance motivation through repeated contacts. The overall aim of this study is to evaluate the impact of a brief lifestyle intervention delivered by community nurses in routine practice on changes in clients' SNAP risk factors. Methods/Design The trial uses a quasi-experimental design involving four generalist community nursing services in NSW Australia. Services have been randomly allocated to an 'early intervention' group or 'late intervention' (comparison group. 'Early intervention' sites are provided with training and support for nurses in identifying and offering brief lifestyle intervention for clients during routine consultations. 'Late intervention site' provide usual care and will be offered the study intervention following the final data collection point. A total of 720 generalist community nursing clients will be recruited at the time of referral from participating sites. Data collection consists of 1 telephone surveys with clients at baseline, three months and six months to examine change in SNAP risk factors and readiness to change 2 nurse survey at baseline, six and 12 months to examine changes in nurse confidence, attitudes and practices in the assessment and management of SNAP risk factors 3 semi-structured interviews/focus with nurses, managers and clients

  2. Modified snap-on attachment with ′O-ring′ for two piece hollow bulb obturator

    Directory of Open Access Journals (Sweden)

    C Gunasekar

    2013-01-01

    Full Text Available Restoration of near normal functions in patients who have been treated with hemimaxillectomy is generally difficult, in view of the restriction in mouth opening following healing of large surgical wound. Further, the extent and nature of the surgical defect differ from patient to patient. Thus, design of an obturator needs to be patient oriented. In this report, we describe a novel snap-on attachment with O-ring in a conventional two piece hollow bulb obturator for a 70-year-old male treated for carcinoma of the left maxilla and sinus.

  3. Helminth infracommunities of the common snapping turtle (Chelydra serpentina serpentina) from Westhampton Lake, Virginia.

    Science.gov (United States)

    Zelmer, Derek A; Platt, Thomas R

    2009-12-01

    Patterns of infracommunity similarity were examined for 27 male and 6 female common snapping turtles, Chelydra serpentina serpentina, collected from Westhampton Lake on the campus of the University of Richmond in Richmond, Virginia, during the summer months of 1979 and 1980. Patterns of infracommunity similarity based on parasite abundance emphasized differences between years and between host sexes. Patterns of similarity based on parasite presence or absence emphasized differences among the months sampled. This suggests that there were consistent seasonal changes across both years in terms of which parasites were present, but that there were differences between years in terms of the abundances of those parasites.

  4. Comparison of CLASS and ITK-SNAP in segmentation of urinary bladder in CT urography

    Science.gov (United States)

    Cha, Kenny; Hadjiiski, Lubomir; Chan, Heang-Ping; Caoili, Elaine M.; Cohan, Richard H.; Zhou, Chuan

    2014-03-01

    We are developing a computerized method for bladder segmentation in CT urography (CTU) for computeraided diagnosis of bladder cancer. We have developed a Conjoint Level set Analysis and Segmentation System (CLASS) consisting of four stages: preprocessing and initial segmentation, 3D and 2D level set segmentation, and post-processing. In case the bladder contains regions filled with intravenous (IV) contrast and without contrast, CLASS segments the noncontrast (NC) region and the contrast (C) filled region separately and conjoins the contours. In this study, we compared the performance of CLASS to ITK-SNAP 2.4, which is a publicly available software application for segmentation of structures in 3D medical images. ITK-SNAP performs segmentation by using the edge-based level set on preprocessed images. The level set were initialized by manually placing a sphere at the boundary between the C and NC parts of the bladders with C and NC regions, and in the middle of the bladders that had only C or NC region. Level set parameters and the number of iterations were chosen after experimentation with bladder cases. Segmentation performances were compared using 30 randomly selected bladders. 3D hand-segmented contours were obtained as reference standard, and computerized segmentation accuracy was evaluated in terms of the average volume intersection %, average % volume error, average absolute % volume error, average minimum distance, and average Jaccard index. For CLASS, the values for these performance metrics were 79.0±8.2%, 16.1±16.3%, 19.9±11.1%, 3.5±1.3 mm, 75.7±8.4%, respectively. For ITK-SNAP, the corresponding values were 78.8±8.2%, 8.3±33.1%, 24.2±23.7%, 5.2±2.6 mm, 71.0±15.4%, respectively. CLASS on average performed better and exhibited less variations than ITK-SNAP for bladder segmentation.

  5. Calculation of the real part of the nuclear amplitude at high s and small t from the Coulomb amplitude

    Energy Technology Data Exchange (ETDEWEB)

    Gauron, P.; Nicolescu, B. [Universite Pierre et Marie Curie, Theory Group, Lab. de Physique Nucleaire et des Hautes Energies (LPNHE), CNRS 75 - Paris (France)

    2005-07-01

    A new method for the determination of the real part of the elastic scattering amplitude is examined for high energy proton-proton at small momentum transfer. This method allows us to decrease the number of model assumptions, to obtain the real part in a narrow region of momentum transfer and to test different models. The possible non-exponential behavior of the real part was found on the base of the analysis of the ISR experimental data. (authors)

  6. Multiparametric amplitude analysis with on-line compression using adaptive orthogonal transform

    Energy Technology Data Exchange (ETDEWEB)

    Morhac, M; Matousek, V; Turzo, I

    1996-12-31

    The new method of multiparameter amplitude analysis with on-line compression is developed. The proposed method decreases the memory needed to store multidimensional histograms. Examples of employing the algorithms for three-dimensional spectra are presented. 5 refs.

  7. Holographic corrections to meson scattering amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Armoni, Adi; Ireson, Edwin, E-mail: 746616@swansea.ac.uk

    2017-06-15

    We compute meson scattering amplitudes using the holographic duality between confining gauge theories and string theory, in order to consider holographic corrections to the Veneziano amplitude and associated higher-point functions. The generic nature of such computations is explained, thanks to the well-understood nature of confining string backgrounds, and two different examples of the calculation in given backgrounds are used to illustrate the details. The effect we discover, whilst only qualitative, is re-obtainable in many such examples, in four-point but also higher point amplitudes.

  8. Amplitude-Mode Dynamics of Polariton Condensates

    International Nuclear Information System (INIS)

    Brierley, R. T.; Littlewood, P. B.; Eastham, P. R.

    2011-01-01

    We study the stability of collective amplitude excitations in nonequilibrium polariton condensates. These excitations correspond to renormalized upper polaritons and to the collective amplitude modes of atomic gases and superconductors. They would be present following a quantum quench or could be created directly by resonant excitation. We show that uniform amplitude excitations are unstable to the production of excitations at finite wave vectors, leading to the formation of density-modulated phases. The physical processes causing the instabilities can be understood by analogy to optical parametric oscillators and the atomic Bose supernova.

  9. Hidden simplicity of gauge theory amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, J M, E-mail: drummond@lapp.in2p3.f [LAPTH, Universite de Savoie, CNRS, B.P. 110, F-74941 Annecy-le-Vieux, Cedex (France)

    2010-11-07

    These notes were given as lectures at the CERN Winter School on Supergravity, Strings and Gauge Theory 2010. We describe the structure of scattering amplitudes in gauge theories, focussing on the maximally supersymmetric theory to highlight the hidden symmetries which appear. Using the Britto, Cachzo, Feng and Witten (BCFW) recursion relations we solve the tree-level S-matrix in N=4 super Yang-Mills theory and describe how it produces a sum of invariants of a large symmetry algebra. We review amplitudes in the planar theory beyond tree level, describing the connection between amplitudes and Wilson loops, and discuss the implications of the hidden symmetries.

  10. A fluorogenic probe for SNAP-tagged plasma membrane proteins based on the solvatochromic molecule Nile Red.

    Science.gov (United States)

    Prifti, Efthymia; Reymond, Luc; Umebayashi, Miwa; Hovius, Ruud; Riezman, Howard; Johnsson, Kai

    2014-03-21

    A fluorogenic probe for plasma membrane proteins based on the dye Nile Red and SNAP-tag is introduced. It takes advantage of Nile Red, a solvatochromic molecule highly fluorescent in an apolar environment, such as cellular membranes, but almost dark in a polar aqueous environment. The probe possesses a tuned affinity for membranes allowing its Nile Red moiety to insert into the lipid bilayer of the plasma membrane, becoming fluorescent, only after its conjugation to a SNAP-tagged plasma membrane protein. The fluorogenic character of the probe was demonstrated for different SNAP-tag fusion proteins, including the human insulin receptor. This work introduces a new approach for generating a powerful turn-on probe for "no-wash" labeling of plasma membrane proteins with numerous applications in bioimaging.

  11. Synaptosomal-associated protein 25 (Snap-25) gene polymorphism frequency in fibromyalgia syndrome and relationship with clinical symptoms.

    Science.gov (United States)

    Balkarli, Ayse; Sengül, Cem; Tepeli, Emre; Balkarli, Huseyin; Cobankara, Veli

    2014-05-31

    SNAP-25 protein is contributory to plasma membrane and synaptic vesicle fusions that are critical points in neurotransmission. SNAP-25 gene is associated with behavioral symptoms, personality and psychological disorders. In addition, SNAP-25 protein can be related to different neurotransmitter functions due to its association with vesicle membrane transition and fusion. This is important because neurologic, cognitive, and psychologic disorders in fibromyalgia syndrome (FMS) can be related to this function. This relationship may be enlightening for etiopathogenesis of FMS and treatment approaches. We aimed to study a SNAP-25 gene polymorphism, which is related to many psychiatric diseases, and FMS association in this prospective study. We included 71 patients who were diagnosed according to new criteria and 57 matched healthy women in this study. Both groups were evaluated regarding age, height, weight, BMI, education level, marital and occupational status. A new diagnosis of FMS was made from criteria scoring, SF-36, Beck depression scale, and VAS that were applied to the patient group. SNAP-25 gene polymorphism and disease activity score correlations were compared. Mean age was 38±5,196 and 38.12±4.939 in patient and control groups, respectively (p=0.542). No significant difference was found between groups regarding age, height, weight, BMI, education level, marital or occupational status (p > 0.05). Ddel T/C genotype was significantly higher in the patient group (p = 0.009). MnlI gene polymorphism did not show a correlation with any score whereas a significant correlation was found between Ddel T/C genotype and Beck depression scale and VAS score (p < 0.05). FMS etiopathogenesis is not clearly known. Numerous neurologic, cognitive and psychological disorders were found during studies looking at cause. Our study showed increased SNAP-25 Ddel T/C genotype in FMS patients compared to the control group, which is related to behavioral symptoms, personality and

  12. Analytic continuation of dual Feynman amplitudes

    International Nuclear Information System (INIS)

    Bleher, P.M.

    1981-01-01

    A notion of dual Feynman amplitude is introduced and a theorem on the existence of analytic continuation of this amplitude from the convergence domain to the whole complex is proved. The case under consideration corresponds to massless power propagators and the analytic continuation is constructed on the propagators powers. Analytic continuation poles and singular set of external impulses are found explicitly. The proof of the theorem on the existence of analytic continuation is based on the introduction of α-representation for dual Feynman amplitudes. In proving, the so-called ''trees formula'' and ''trees-with-cycles formula'' are established that are dual by formulation to the trees and 2-trees formulae for usual Feynman amplitudes. (Auth.)

  13. Amplitude-Integrated EEG in the Newborn

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2008-11-01

    Full Text Available Th value of amplitude-integrated electroencephalography (aEEG in the newborn is explored by researchers at Washington University, St Louis; Wilhelmina Children’s Hospital, Utrecht, Netherlands; and Uppsala University Hospital, Sweden.

  14. Effective string theory and QCD scattering amplitudes

    International Nuclear Information System (INIS)

    Makeenko, Yuri

    2011-01-01

    QCD string is formed at distances larger than the confinement scale and can be described by the Polchinski-Strominger effective string theory with a nonpolynomial action, which has nevertheless a well-defined semiclassical expansion around a long-string ground state. We utilize modern ideas about the Wilson-loop/scattering-amplitude duality to calculate scattering amplitudes and show that the expansion parameter in the effective string theory is small in the Regge kinematical regime. For the amplitudes we obtain the Regge behavior with a linear trajectory of the intercept (d-2)/24 in d dimensions, which is computed semiclassically as a momentum-space Luescher term, and discuss an application to meson scattering amplitudes in QCD.

  15. Scattering Amplitudes via Algebraic Geometry Methods

    CERN Document Server

    Søgaard, Mads; Damgaard, Poul Henrik

    This thesis describes recent progress in the understanding of the mathematical structure of scattering amplitudes in quantum field theory. The primary purpose is to develop an enhanced analytic framework for computing multiloop scattering amplitudes in generic gauge theories including QCD without Feynman diagrams. The study of multiloop scattering amplitudes is crucial for the new era of precision phenomenology at the Large Hadron Collider (LHC) at CERN. Loop-level scattering amplitudes can be reduced to a basis of linearly independent integrals whose coefficients are extracted from generalized unitarity cuts. We take advantage of principles from algebraic geometry in order to extend the notion of maximal cuts to a large class of two- and three-loop integrals. This allows us to derive unique and surprisingly compact formulae for the coefficients of the basis integrals. Our results are expressed in terms of certain linear combinations of multivariate residues and elliptic integrals computed from products of ...

  16. Effect of surface roughness on ultrasonic echo amplitude in aluminium-copper alloy castings

    International Nuclear Information System (INIS)

    Ambardar, R.; Pathak, S.D.; Prabhakar, O.; Jayakumar, T.

    1996-01-01

    In the present investigation, the influence of test surface roughness on ultrasonic back-wall echo (BWE) amplitude in Al-4.5%Cu alloy cast specimens has been studied. The results indicate that as the value of surface roughness of the specimen increases, the value of relating BWE amplitude at a given probe frequency decreases. However, under the present set of experimental conditions, the decrease in BWE amplitude with the increase in surface roughness of the test specimen is found to be appreciable at 10 MHz probe frequency. (author)

  17. Effective gluon interactions from superstring disk amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Oprisa, D.

    2006-05-15

    In this thesis an efficient method for the calculation of the N-point tree-level string amplitudes is presented. Furthermore it is shown that the six-gluon open-superstring disk amplitude can be expressed by a basis of six triple hypergeometric functions, which encode the full {alpha}' dependence. In this connection material for obtaining the {alpha}' expansion of these functions is derived. Hereby many Euler-Zagier sums are calculated including multiple harmonic series. (HSI)

  18. Effective gluon interactions from superstring disk amplitudes

    International Nuclear Information System (INIS)

    Oprisa, D.

    2006-05-01

    In this thesis an efficient method for the calculation of the N-point tree-level string amplitudes is presented. Furthermore it is shown that the six-gluon open-superstring disk amplitude can be expressed by a basis of six triple hypergeometric functions, which encode the full α' dependence. In this connection material for obtaining the α' expansion of these functions is derived. Hereby many Euler-Zagier sums are calculated including multiple harmonic series. (HSI)

  19. Employing helicity amplitudes for resummation in SCET

    International Nuclear Information System (INIS)

    Moult, Ian; Stewart, Iain W.; Tackmann, Frank J.; Waalewijn, Wouter J.; Nikhef, Amsterdam

    2016-05-01

    Helicity amplitudes are the fundamental ingredients of many QCD calculations for multi-leg processes. We describe how these can seamlessly be combined with resummation in Soft-Collinear Effective Theory (SCET), by constructing a helicity operator basis for which the Wilson coefficients are directly given in terms of color-ordered helicity amplitudes. This basis is crossing symmetric and has simple transformation properties under discrete symmetries.

  20. The amplitude of quantum field theory

    International Nuclear Information System (INIS)

    Medvedev, B.V.; Pavlov, V.P.; Polivanov, M.K.; Sukhanov, A.D.

    1989-01-01

    General properties of the transition amplitude in axiomatic quantum field theory are discussed. Bogolyubov's axiomatic method is chosen as the variant of the theory. The axioms of this method are analyzed. In particular, the significance of the off-shell extension and of the various forms of the causality condition are examined. A complete proof is given of the existence of a single analytic function whose boundary values are the amplitudes of all channels of a process with given particle number

  1. The Cepheid bump progression and amplitude equations

    International Nuclear Information System (INIS)

    Kovacs, G.; Buchler, J.R.

    1989-01-01

    It is shown that the characteristic and systematic behavior of the low-order Fourier amplitudes and phases of hydrodynamically generated radial velocity and light curves of Cepheid model sequences is very well captured not only qualitatively but also quantitatively by the amplitude equation formalism. The 2:1 resonance between the fundamental and the second overtone plays an essential role in the behavior of the models 8 refs

  2. The Schedule for Nonadaptive and Adaptive Personality for Youth (SNAP-Y): A New Measure for Assessing Adolescent Personality and Personality Pathology

    Science.gov (United States)

    Linde, Jennifer A.; Stringer, Deborah; Simms, Leonard J.; Clark, Lee Anna

    2013-01-01

    The Schedule for Nonadaptive and Adaptive Personality-Youth Version (SNAP-Y) is a new, reliable self-report questionnaire that assesses 15 personality traits relevant to both normal-range personality and the alternative "DSM"-5 model for personality disorder. Community adolescents, 12 to 18 years old (N = 364), completed the SNAP-Y; 347…

  3. A Multilevel Functional Study of a SNAP25 At-Risk Variant for Bipolar Disorder and Schizophrenia.

    Science.gov (United States)

    Houenou, Josselin; Boisgontier, Jennifer; Henrion, Annabelle; d'Albis, Marc-Antoine; Dumaine, Anne; Linke, Julia; Wessa, Michèle; Daban, Claire; Hamdani, Nora; Delavest, Marine; Llorca, Pierre-Michel; Lançon, Christophe; Schürhoff, Franck; Szöke, Andrei; Le Corvoisier, Philippe; Barau, Caroline; Poupon, Cyril; Etain, Bruno; Leboyer, Marion; Jamain, Stéphane

    2017-10-25

    The synaptosomal-associated protein SNAP25 is a key player in synaptic vesicle docking and fusion and has been associated with multiple psychiatric conditions, including schizophrenia, bipolar disorder, and attention-deficit/hyperactivity disorder. We recently identified a promoter variant in SNAP25 , rs6039769 , that is associated with early-onset bipolar disorder and a higher gene expression level in human prefrontal cortex. In the current study, we showed that this variant was associated both in males and females with schizophrenia in two independent cohorts. We then combined in vitro and in vivo approaches in humans to understand the functional impact of the at-risk allele. Thus, we showed in vitro that the rs6039769 C allele was sufficient to increase the SNAP25 transcription level. In a postmortem expression analysis of 33 individuals affected with schizophrenia and 30 unaffected control subjects, we showed that the SNAP25b / SNAP25a ratio was increased in schizophrenic patients carrying the rs6039769 at-risk allele. Last, using genetics imaging in a cohort of 71 subjects, we showed that male risk carriers had an increased amygdala-ventromedial prefrontal cortex functional connectivity and a larger amygdala than non-risk carriers. The latter association has been replicated in an independent cohort of 121 independent subjects. Altogether, results from these multilevel functional studies are bringing strong evidence for the functional consequences of this allelic variation of SNAP25 on modulating the development and plasticity of the prefrontal-limbic network, which therefore may increase the vulnerability to both early-onset bipolar disorder and schizophrenia. SIGNIFICANCE STATEMENT Functional characterization of disease-associated variants is a key challenge in understanding neuropsychiatric disorders and will open an avenue in the development of personalized treatments. Recent studies have accumulated evidence that the SNARE complex, and more specifically

  4. Developmental and Diurnal Expression of the Synaptosomal-Associated Protein 25 (Snap25) in the Rat Pineal Gland

    DEFF Research Database (Denmark)

    Karlsen, Anna S; Rath, Martin Fredensborg; Rohde, Kristian

    2013-01-01

    pineal gland but the biological importance of this is unknown. In this study, we demonstrate a high expression of mRNA encoding Snap25 in all parts of the rat pineal complex, the superficial-, and deep-pineal gland, as well as in the pineal stalk. Snap25 showed a low pineal expression during embryonic...... stages with a strong increase in expression levels just after birth. The expression showed no day/night variations. Neither removal of the sympathetic input to the pineal gland by superior cervical ganglionectomy nor bilateral decentralization of the superior cervical ganglia significantly affected...

  5. Effects of environmental contaminants on snapping turtles of a tidal wetland

    Energy Technology Data Exchange (ETDEWEB)

    Albers, P H; Sileo, L; Mulhern, B M

    1986-01-01

    Snapping turtles (Chelydra serpentina) were collected from a brackish-water and a nearly freshwater area in the contaminated Hackensack Meadowlands of New Jersey and an uncontaminated freshwater area in Maryland to determine the effects of environmental contaminants on a resident wetland species. No turtles were observed or caught in Meadowlands at two trapping sites that were the most heavily contaminated by metals. Snapping turtles from the brackish-water area had an unusually low lipid content of body fat and reduced growth compared to turtles from the freshwater areas in New Jersey and Maryland. Despite the serious metal contamination of the Hackensack Meadowlands, the metal content of kidneys and livers from New Jersey turtles was low and not greatly different from that of the Maryland turtles. Organochlorine pesticide concentrations in body fat were generally low at all three study areas. Polychlorinated biphenyls (PCBs) concentrations in fat were highest in male turtles from the New Jersey brackish-water area. Analysis of blood for amino-levulinic acid dehydratase, albumin, glucose, hemoglobin, osmolatility, packed cell volume, total protein, triglycerides, and uric acid failed to reveal any differences among groups that would indicated physiological impairment related to contaminants.

  6. Diatoms on the carapace of common snapping turtles: Luticola spp. dominate despite spatial variation in assemblages.

    Directory of Open Access Journals (Sweden)

    Shelly C Wu

    Full Text Available Filamentous algae are often visible on the carapaces of freshwater turtles and these algae are dominated by a few species with varying geographic distributions. Compared to filamentous algae, little is known about the much more speciose microalgae on turtles. Our objectives were to compare the diatom flora on a single turtle species (the common snapping turtle, Chelydra serpentina across part of its range to examine spatial patterns and determine whether specific diatom taxa were consistently associated with turtles (as occurs in the filamentous alga Basicladia spp.. Using preserved turtle specimens from museums, we systematically sampled diatoms on the carapaces of 25 snapping turtles across five states. The diverse diatom assemblages formed two groups-the southern Oklahoma group and the northern Illinois/Wisconsin/New York group, with Arkansas not differing from either group. Of the six diatom species found in all five states, four species are widespread, whereas Luticola cf. goeppertiana and L. cf. mutica are undescribed species, known only from turtles in our study. L. cf. goeppertiana comprised 83% of the diatom abundance on Oklahoma turtles and was relatively more abundant on southern turtles (Oklahoma and Arkansas than on northern turtles (where mean abundance/state was > 10%. L. cf. mutica was the most abundant species (40% on New York turtles. Some Luticola species are apparently turtle associates and results support a pattern of spatial variation in Luticola species, similar to that in Basicladia. Using museum specimens is an efficient and effective method to study the distribution of micro-epibionts.

  7. High levels of maternally transferred mercury disrupt magnetic responses of snapping turtle hatchlings (Chelydra serpentina).

    Science.gov (United States)

    Landler, Lukas; Painter, Michael S; Coe, Brittney Hopkins; Youmans, Paul W; Hopkins, William A; Phillips, John B

    2017-09-01

    The Earth's magnetic field is involved in spatial behaviours ranging from long-distance migration to non-goal directed behaviours, such as spontaneous magnetic alignment (SMA). Mercury is a harmful pollutant most often generated from anthropogenic sources that can bio-accumulate in animal tissue over a lifetime. We compared SMA of hatchling snapping turtles from mothers captured at reference (i.e., low mercury) and mercury contaminated sites. Reference turtles showed radio frequency-dependent SMA along the north-south axis, consistent with previous studies of SMA, while turtles with high levels of maternally inherited mercury failed to show consistent magnetic alignment. In contrast, there was no difference between reference and mercury exposed turtles on standard performance measures. The magnetic field plays an important role in animal orientation behaviour and may also help to integrate spatial information from a variety of sensory modalities. As a consequence, mercury may compromise the performance of turtles in a wide variety of spatial tasks. Future research is needed to determine the threshold for mercury effects on snapping turtles, whether mercury exposure compromises spatial behaviour of adult turtles, and whether mercury has a direct effect on the magnetoreception mechanism(s) that mediate SMA or a more general effect on the nervous system. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Effects of environmental contaminants on snapping turtles of a tidal wetland

    Science.gov (United States)

    Albers, P.H.; Sileo, L.; Mulhern, B.M.

    1986-01-01

    Snapping turtles (Chelydra serpentina) were collected from a brackish-water and a nearly freshwater area in the contaminated Hackensack Meadowlands of New Jersey and an uncontaminated freshwater area in Maryland to determine the effects of environmental contaminants on a resident wetland species. No turtles were observed or caught in the Meadowlands at two trapping sites that were the most heavily contaminated by metals. Snapping turtles from the brackish-water area had an unusually low lipid content of body fat and reduced growth compared to turtles from the fresh-water areas in New Jersey and Maryland. Despite the serious metal contamination of the Hackensack Meadowlands, the metal content of kidneys and livers from New Jersey turtles was low and not greatly different from that of the Maryland turtles. Organochlorine pesticide concentrations in body fat were generally low at all three study areas. Polychlorinated biphenyls (PCBs) concentrations in fat were highest in male turtles from the New Jersey brackish-water area. Analysis of blood for amino-levulinic acid dehydratase, albumin, glucose, hemoglobin, osmolality, packed cell volume, total protein, triglycerides, and uric acid failed to reveal any differences among groups that would indicate physiological impairment related to contaminants.

  9. Temperature effects on snapping performance in the common snapper Chelydra serpentina (Reptilia, Testudines).

    Science.gov (United States)

    Vervust, Bart; Brecko, Jonathan; Herrel, Anthony

    2011-01-01

    Studies on the effect of temperature on whole-animal performance traits other than locomotion are rare. Here we investigate the effects of temperature on the performance of the turtle feeding apparatus in a defensive context. We measured bite force and the kinematics of snapping in the Common Snapping Turtle (Chelydra serpentina) over a wide range of body temperatures. Bite force performance was thermally insensitive over the broad range of temperatures typically experienced by these turtles in nature. In contrast, neck extension (velocity, acceleration, and deceleration) and jaw movements (velocity, acceleration, and deceleration) showed clear temperature dependence with peak acceleration and deceleration capacity increasing with increasing temperatures. Our results regarding the temperature dependence of defensive behavior are reflected by the ecology and overall behavior of this species. These data illustrate the necessity for carefully controlling T(b) when carrying out behavioral and functional studies on turtles as temperature affects the velocity, acceleration, and deceleration of jaw and neck extension movements. More generally, these data add to the limited but increasing number of studies showing that temperature may have important effects on feeding and defensive performance in ectotherms. © 2010 Wiley-Liss, Inc.

  10. Effects of environmentally relevant concentrations of atrazine on gonadal development of snapping turtles (Chelydra serpentina).

    Science.gov (United States)

    de Solla, Shane R; Martin, Pamela A; Fernie, Kimberly J; Park, Brad J; Mayne, Gregory

    2006-02-01

    The herbicide atrazine has been suspected of affecting sexual development by inducing aromatase, resulting in the increased conversion of androgens to estrogens. We used snapping turtles (Chelydra serpentina), a species in which sex is dependent on the production of estrogen through aromatase activity in a temperature-dependent manner, to investigate if environmentally relevant exposures to atrazine affected gonadal development. Eggs were incubated in soil to which atrazine was applied at a typical field application rate (3.1 L/ha), 10-fold this rate (31 L/ha), and a control rate (no atrazine) for the duration of embryonic development. The incubation temperature (25 degrees C) was selected to produce only males. Although some males with testicular oocytes and females were produced in the atrazine-treated groups (3.3-3.7%) but not in the control group, no statistical differences were found among treatments. Furthermore, snapping turtle eggs collected from natural nests in a corn field were incubated at the pivotal temperature (27.5 degrees C) at which both males and females normally would be produced, and some males had oocytes in the testes (15.4%). The presence of low numbers of males with oocytes may be a natural phenomenon, and we have limited evidence to suggest that the presence of normal males with oocytes may represent a feminizing effect of atrazine. Histological examination of the thyroid gland revealed no effect on thyroid morphology.

  11. Diatoms on the carapace of common snapping turtles: Luticola spp. dominate despite spatial variation in assemblages

    Science.gov (United States)

    Wu, Shelly C.; Bergey, Elizabeth A.

    2017-01-01

    Filamentous algae are often visible on the carapaces of freshwater turtles and these algae are dominated by a few species with varying geographic distributions. Compared to filamentous algae, little is known about the much more speciose microalgae on turtles. Our objectives were to compare the diatom flora on a single turtle species (the common snapping turtle, Chelydra serpentina) across part of its range to examine spatial patterns and determine whether specific diatom taxa were consistently associated with turtles (as occurs in the filamentous alga Basicladia spp.). Using preserved turtle specimens from museums, we systematically sampled diatoms on the carapaces of 25 snapping turtles across five states. The diverse diatom assemblages formed two groups–the southern Oklahoma group and the northern Illinois/Wisconsin/New York group, with Arkansas not differing from either group. Of the six diatom species found in all five states, four species are widespread, whereas Luticola cf. goeppertiana and L. cf. mutica are undescribed species, known only from turtles in our study. L. cf. goeppertiana comprised 83% of the diatom abundance on Oklahoma turtles and was relatively more abundant on southern turtles (Oklahoma and Arkansas) than on northern turtles (where mean abundance/state was > 10%). L. cf. mutica was the most abundant species (40%) on New York turtles. Some Luticola species are apparently turtle associates and results support a pattern of spatial variation in Luticola species, similar to that in Basicladia. Using museum specimens is an efficient and effective method to study the distribution of micro-epibionts. PMID:28192469

  12. Critical Windows of Cardiovascular Susceptibility to Developmental Hypoxia in Common Snapping Turtle (Chelydra serpentina) Embryos.

    Science.gov (United States)

    Tate, Kevin B; Kohl, Zachary F; Eme, John; Rhen, Turk; Crossley, Dane A

    2015-01-01

    Environmental conditions fluctuate dramatically in some reptilian nests. However, critical windows of environmental sensitivity for cardiovascular development have not been identified. Continuous developmental hypoxia has been shown to alter cardiovascular form and function in embryonic snapping turtles (Chelydra serpentina), and we used this species to identify critical periods during which hypoxia modifies the cardiovascular phenotype. We hypothesized that incubation in 10% O2 during specific developmental periods would have differential effects on the cardiovascular system versus overall somatic growth. Two critical windows were identified with 10% O2 from 50% to 70% of incubation, resulting in relative heart enlargement, either via preservation of or preferential growth of this tissue, while exposure to 10% O2 from 20% to 70% of incubation resulted in a reduction in arterial pressure. The deleterious or advantageous aspects of these embryonic phenotypes in posthatching snapping turtles have yet to be explored. However, identification of these critical windows has provided insight into how the developmental environment alters the phenotype of reptiles and will also be pivotal in understanding its impact on the fitness of egg-laying reptiles.

  13. Secretory proteins in the reproductive tract of the snapping turtle, Chelhydra serpentina.

    Science.gov (United States)

    Mahmoud, I Y; Paulson, J R; Dudley, M; Patzlaff, J S; Al-Kindi, A Y A

    2004-12-01

    SDS-polyacrylamide gel electrophoresis was used to separate the secretory proteins produced by the epithelial and endometrial glands of the uterine tube and uterus in the snapping turtle Chelydra serpentina. The proteins were analyzed throughout the phases of the reproductive cycle from May to August, including preovulatory, ovulatory, postovulatory or luteal, and vitellogenic phases. The pattern of secretory proteins is quite uniform along the length of the uterine tube, and the same is true of the uterus, but the patterns for uterine tube and uterus are clearly different. We identify 13 major proteins in C. serpentina egg albumen. Bands co-migrating with 11 of these are found in the uterine tube, but at most 4 are found in the uterus, suggesting that the majority of the albumen proteins are most likely secreted in the uterine tube, not in the uterus. Although some of the egg albumen proteins are present in the uterine tube only at the time of ovulation, most of the bands corresponding to albumen proteins are present throughout the breeding season even though the snapping turtle is a monoclutch species. These results suggest that the glandular secretory phase in the uterine tube is active and quite homogeneous in function regardless of location or phase of the reproductive cycle.

  14. Snap-lock bags with red band: A study of manufacturing characteristics, thermal and chemical properties.

    Science.gov (United States)

    Sim, Yvonne Hui Ying; Koh, Alaric C W; Lim, Shing Min; Yew, Sok Yee

    2015-10-01

    Drug packaging is commonly submitted to the Forensic Chemistry and Physics Laboratory of the Health Sciences Authority, Singapore, for examination. The drugs seized are often packaged in plastic bags. These bags are examined for linkages to provide law enforcement with useful associations between the traffickers and drug abusers. The plastic bags submitted may include snap-lock bags, some with a red band located above the snap-lock closure and some without. Current techniques for examination involve looking at the physical characteristics (dimensions, thickness and polarising patterns) and manufacturing marks of these bags. In cases where manufacturing marks on the main body of the bags are poor or absent, the manufacturing characteristics present on the red band can be examined. A study involving approximately 1000 bags was conducted to better understand the variations in the manufacturing characteristics of the red band. This understanding is crucial in helping to determine associations/eliminations between bags. Two instrumental techniques, namely differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FT-IR) were explored to evaluate the effectiveness of examining the chemical composition to discriminate the bags. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  15. Endoscopically assisted resection of a scapular osteochondroma causing snapping scapula syndrome

    Directory of Open Access Journals (Sweden)

    Futani Hiroyuki

    2007-03-01

    Full Text Available Abstract Background Osteochondroma is the most common benign bone tumor in the scapula. This condition might lead to snapping scapula syndrome, which is characterized by painful, audible, and/or palpable abnormal scapulothoracic motion. In the present case, this syndrome was successfully treated by use of endoscopically assisted resection of the osteochondroma. Case presentation A 41-year-old man had a tolerable pain in his scapular region over a 10 years' period. The pain developed gradually with shoulder motion, in particular with golf swing since he was aiming a professional golf player career. On physical examination, "clunking" was noted once from 90 degrees of abduction to 180 degrees of shoulder motion. A trans-scapular roentgenogram and computed tomography images revealed an osteochondroma located at the anterior and inferior aspect of the scapula. Removal of the tumor was performed by the use of endoscopically assisted resection. One portal was made at the lateral border of the scapula to introduce a 2.7-mm-diameter, 30 degrees Hopkins telescope. The tumor was resected in a piece-by-piece manner by the use of graspers through the same portal. Immediately after the operation pain relief was obtained, and the "clunking" disappeared. CT images showed complete tumor resection. The patient could start playing golf one week after the surgery. Conclusion Endoscopically assisted resection of osteochondroma of the scapula provides a feasible technique to treat snapping scapula syndrome and obtain early functional recovery with a short hospital stay and cosmetic advantage.

  16. Identifying mechanisms that structure ecological communities by snapping model parameters to empirically observed tradeoffs.

    Science.gov (United States)

    Thomas Clark, Adam; Lehman, Clarence; Tilman, David

    2018-04-01

    Theory predicts that interspecific tradeoffs are primary determinants of coexistence and community composition. Using information from empirically observed tradeoffs to augment the parametrisation of mechanism-based models should therefore improve model predictions, provided that tradeoffs and mechanisms are chosen correctly. We developed and tested such a model for 35 grassland plant species using monoculture measurements of three species characteristics related to nitrogen uptake and retention, which previous experiments indicate as important at our site. Matching classical theoretical expectations, these characteristics defined a distinct tradeoff surface, and models parameterised with these characteristics closely matched observations from experimental multi-species mixtures. Importantly, predictions improved significantly when we incorporated information from tradeoffs by 'snapping' characteristics to the nearest location on the tradeoff surface, suggesting that the tradeoffs and mechanisms we identify are important determinants of local community structure. This 'snapping' method could therefore constitute a broadly applicable test for identifying influential tradeoffs and mechanisms. © 2018 The Authors. Ecology Letters published by CNRS and John Wiley & Sons Ltd.

  17. Towards Lego Snapping; Integration of Carbon Nanotubes and Few-Layer Graphene

    Science.gov (United States)

    Nasseri, Mohsen; Boland, Mathias; Farrokhi, M. Javad; Strachan, Douglas

    Integration of semiconducting, conducting, and insulating nanomaterials into precisely aligned complicated systems is one of the main challenges to the ultimate size scaling of electronic devices, which is a key goal in nanoscience and nanotechnology. This integration could be made more effective through controlled alignment of the crystallographic lattices of the nanoscale components. Of the vast number of materials of atomically-thin materials, two of the sp2 bonded carbon structures, graphene and carbon nanotubes, are ideal candidates for this type of application since they are built from the same backbone carbon lattice. Here we report carbon nanotube and graphene hybrid nanostructures fabricated through their catalytic synthesis and etching. The growth formations we have investigated through various high-resolution microscopy techniques provide evidence of lego-snapped interfaces between nanotubes and graphene into device-relevant orientations. We will finish with a discussion of the various size and energy regimes relevant to these lego-snapped interfaces and their implications on developing these integrated formations.

  18. APPRAISAL OF THE SNAP MODEL FOR PREDICTING NITROGEN MINERALIZATION IN TROPICAL SOILS UNDER EUCALYPTUS

    Directory of Open Access Journals (Sweden)

    Philip James Smethurst

    2015-04-01

    Full Text Available The Soil Nitrogen Availability Predictor (SNAP model predicts daily and annual rates of net N mineralization (NNM based on daily weather measurements, daily predictions of soil water and soil temperature, and on temperature and moisture modifiers obtained during aerobic incubation (basal rate. The model was based on in situ measurements of NNM in Australian soils under temperate climate. The purpose of this study was to assess this model for use in tropical soils under eucalyptus plantations in São Paulo State, Brazil. Based on field incubations for one month in three, NNM rates were measured at 11 sites (0-20 cm layer for 21 months. The basal rate was determined in in situ incubations during moist and warm periods (January to March. Annual rates of 150-350 kg ha-1 yr-1 NNM predicted by the SNAP model were reasonably accurate (R2 = 0.84. In other periods, at lower moisture and temperature, NNM rates were overestimated. Therefore, if used carefully, the model can provide adequate predictions of annual NNM and may be useful in practical applications. For NNM predictions for shorter periods than a year or under suboptimal incubation conditions, the temperature and moisture modifiers need to be recalibrated for tropical conditions.

  19. Determinatio of Psychometrics Index of SNAP-IV Rating Scale in Parents Execution

    Directory of Open Access Journals (Sweden)

    Seyyed Jalal Sadrosadat

    2008-01-01

    Full Text Available Objective: SNAP-IV rating scale to diagnosis Attention Deficit Hyperactivity Disorder (ADHD developed by Swanson, Nolan and Pelham. The aim of this study is determination of psychometrics specifications of this scale. Materials & Methods: This Descriptive research is a methodological, applied and validity assessment study. One thousand students at 7 to 12 age of primary school in Tehran city were selected by cluster sampling. Then the students mothers was asked to complete rating scale to consider behavior of their children.30 staff members of sample group were retest after one mounts. Diagnostic interview was administered at 36 members of sample group. Data were analyzed by using pearsonian correlation coefficient, Kolmogorof – Smirnoff and Behrens – Fisher T test. Results: Criterion validity was 48%, factor analysis was detected 3 factors that explain 56% of the total variance. Reliability coefficient was 82% . internal consistency coefficient was 90% and split –half coefficient was 76%, Cut-off point in scale and subscales was 1.57,1.47 and 1.9 respectively. Conclusion: The SNAP-IV Rating scales have fit psychometrics specifications. Therefore, it is useable in various diagnostic and therapeutic conditioning.

  20. Pulsatile secretion of thyrotropin during fasting: a decrease of thyrotropin pulse amplitude

    NARCIS (Netherlands)

    Romijn, J. A.; Adriaanse, R.; Brabant, G.; Prank, K.; Endert, E.; Wiersinga, W. M.

    1990-01-01

    The effect of fasting on circadian and pulsatile TSH secretion was investigated in eight healthy subjects (four men and four women in the follicular phase). Each subject was studied twice, once during 24 h with normal food intake and once during the last 24 h of a 60-h fast. Blood was sampled every

  1. Pump pulse duration dependence of coherent phonon amplitudes in antimony

    Energy Technology Data Exchange (ETDEWEB)

    Misochko, O. V., E-mail: misochko@issp.ac.ru [Russian Academy of Sciences, Institute of Solid State Physics (Russian Federation)

    2016-08-15

    Coherent optical phonons of A{sub 1k} and E{sub k} symmetry in antimony have been studied using the femtosecond pump–probe technique. By varying the pump-pulse duration and keeping the probe duration constant, it was shown that the amplitude of coherent phonons of both symmetries exponentially decreases with increasing pulse width. It was found that the amplitude decay rate for the fully symmetric phonons with larger frequency is greater than that of the doubly degenerate phonons, whereas the frequency and lifetime for coherent phonons of both symmetries do not depend on the pump-pulse duration. Based on this data, the possibility of separation between dynamic and kinematic contributions to the generation mechanism of coherent phonons is discussed.

  2. Pulse amplitude and frequency effects in a pulsed packed column

    International Nuclear Information System (INIS)

    Russell, S.H.

    1954-04-01

    A study has been made of the effect on the efficiency and capacity of applying pulses of varying amplitude and frequency to a packed column. In the efficiency studies, the maximum efficiency was obtained with a pulse having an amplitude of 3/8'' and a frequency of 140 cycles per minute. Under these conditions, the column was about five times as efficient as a simple packed column. Two general types of results were obtained in the capacity studies. Under certain conditions, the capacity increased over that of a simple packed column, but under others, it decreased. Some of the factors causing this were investigated but the fundamental reasons were not determined due to a lack of personnel for the necessary experiments. (author)

  3. Pulse amplitude and frequency effects in a pulsed packed column

    Energy Technology Data Exchange (ETDEWEB)

    Russell, S H

    1954-04-15

    A study has been made of the effect on the efficiency and capacity of applying pulses of varying amplitude and frequency to a packed column. In the efficiency studies, the maximum efficiency was obtained with a pulse having an amplitude of 3/8'' and a frequency of 140 cycles per minute. Under these conditions, the column was about five times as efficient as a simple packed column. Two general types of results were obtained in the capacity studies. Under certain conditions, the capacity increased over that of a simple packed column, but under others, it decreased. Some of the factors causing this were investigated but the fundamental reasons were not determined due to a lack of personnel for the necessary experiments. (author)

  4. Changes in ENSO amplitude under climate warming and cooling

    Science.gov (United States)

    Wang, Yingying; Luo, Yiyong; Lu, Jian; Liu, Fukai

    2018-05-01

    The response of ENSO amplitude to climate warming and cooling is investigated using the Community Earth System Model (CESM), in which the warming and cooling scenarios are designed by adding heat fluxes of equal amplitude but opposite sign onto the ocean surface, respectively. Results show that the warming induces an increase of the ENSO amplitude but the cooling gives rise to a decrease of the ENSO amplitude, and these changes are robust in statistics. A mixed layer heat budget analysis finds that the increasing (decreasing) SST tendency under climate warming (cooling) is mainly due to an enhancement (weakening) of dynamical feedback processes over the equatorial Pacific, including zonal advective (ZA) feedback, meridional advective (MA) feedback, thermocline (TH) feedback, and Ekman (EK) feedback. As the climate warms, a wind anomaly of the same magnitude across the equatorial Pacific can induce a stronger zonal current change in the east (i.e., a stronger ZA feedback), which in turn produces a greater weakening of upwelling (i.e., a stronger EK feedback) and thus a larger thermocline change (i.e., a stronger TH feedback). In response to the climate warming, in addition, the MA feedback is also strengthened due to an enhancement of the meridional SST gradient around the equator resulting from a weakening of the subtropical cells (STCs). It should be noted that the weakened STCs itself has a negative contribution to the change of the MA feedback which, however, appears to be secondary. And vice versa for the cooling case. Bjerknes linear stability (BJ) index is also evaluated for the linear stability of ENSO, with remarkably larger (smaller) BJ index found for the warming (cooling) case.

  5. DETERMINISTIC COMPONENTS IN THE LIGHT CURVE AMPLITUDE OF Y OPH

    International Nuclear Information System (INIS)

    Pop, Alexandru; Turcu, Vlad; Vamos, Calin

    2010-01-01

    About two decades after the discovery of the amplitude decline of the light curve of the classical Cepheid Y Oph, its study is resumed using an increased amount of homogenized data and an extended time base. In our approach, the investigation of different time series concerning the light curve amplitude of Y Oph is not only the reason for the present study, but also a stimulus for developing a coherent methodology for studying long- and short-term variability phenomena in variable stars, taking into account the details of concrete observing conditions: amount of data, data sampling, time base, and individual errors of observational data. The statistical significance of this decreasing trend was estimated by assuming its linearity. We approached the decision-making process by formulating adequate null and alternative hypotheses, and testing the value of the regression line slope for different data sets via Monte Carlo simulations. A variability analysis, through various methods, of the original data and of the residuals obtained after removing the linear trend was performed. We also proposed a new statistical test, based on amplitude spectrum analysis and Monte Carlo simulations, intended to evaluate how detectible is a given (linear) trend in well-defined observing conditions: the trend detection probability. The main conclusion of our study on Y Oph is that, even if the false alarm probability is low enough to consider the decreasing trend to be statistically significant, the available data do not allow us to obtain a reasonably powerful test. We are able to confirm the light curve amplitude decline, and the order of magnitude of its slope with a better statistical substantiation. According to the obtained values of the trend detection probability, it seems that the trend we are dealing with is marked by a low detectibility. Our attempt to find signs of possible variability phenomena at shorter timescales ended by emphasizing the relative constancy of our data

  6. Scattering amplitudes in open superstring theory

    Energy Technology Data Exchange (ETDEWEB)

    Schlotterer, Oliver

    2011-07-15

    The present thesis deals with the theme field of the scattering amplitudes in theories of open superstrings. Especially two different formalisms for the handling of superstrings are introduced and applied for the calaculation of tree-level amplitudes - the Ramond- Neveu-Schwarz (RNS) and the Pure-Spinor (PS) formalism. The RNS approach is proved as flexible in order to describe compactification of the initially ten flat space-time dimensions to four dimensions. We solve the technical problems, which result from the interacting basing world-sheet theory with conformal symmetry. This is used to calculate phenomenologically relevant scattering amplitudes of gluons and quarks as well as production rates of massive harmonic vibrations, which were already identified as virtual exchange particles on the massless level. In the case of a low string mass scale in the range of some Tev the string-specific signatures in parton collisions can be observed in the near future in the LHC experiment at CERN and indicated as first experimental proof of the string theory. THose string effects occur universally for a wide class of string ground states respectively internal geometries and represent an elegant way to avoid the so-called landscape problem of the string theory. A further theme complex in this thesis is based on the PS formalism, which allows a manifestly supersymmetric treatment of scattering amplitudes in ten space-time dimension with sixteen supercharges. We introduce a family of superfields, which occur in massless amplitudes of the open string and can be naturally identified with diagrams of three-valued knots. Thereby we reach not only a compact superspace representation of the n-point field-theory amplitude but can also write the complete superstring n-point amplitude as minimal linear combination of partial amplitudes of the field theory as well as hypergeometric functions. The latter carry the string effects and are analyzed from different perspectives, above all

  7. Scattering amplitudes in open superstring theory

    International Nuclear Information System (INIS)

    Schlotterer, Oliver

    2011-01-01

    The present thesis deals with the theme field of the scattering amplitudes in theories of open superstrings. Especially two different formalisms for the handling of superstrings are introduced and applied for the calaculation of tree-level amplitudes - the Ramond- Neveu-Schwarz (RNS) and the Pure-Spinor (PS) formalism. The RNS approach is proved as flexible in order to describe compactification of the initially ten flat space-time dimensions to four dimensions. We solve the technical problems, which result from the interacting basing world-sheet theory with conformal symmetry. This is used to calculate phenomenologically relevant scattering amplitudes of gluons and quarks as well as production rates of massive harmonic vibrations, which were already identified as virtual exchange particles on the massless level. In the case of a low string mass scale in the range of some Tev the string-specific signatures in parton collisions can be observed in the near future in the LHC experiment at CERN and indicated as first experimental proof of the string theory. THose string effects occur universally for a wide class of string ground states respectively internal geometries and represent an elegant way to avoid the so-called landscape problem of the string theory. A further theme complex in this thesis is based on the PS formalism, which allows a manifestly supersymmetric treatment of scattering amplitudes in ten space-time dimension with sixteen supercharges. We introduce a family of superfields, which occur in massless amplitudes of the open string and can be naturally identified with diagrams of three-valued knots. Thereby we reach not only a compact superspace representation of the n-point field-theory amplitude but can also write the complete superstring n-point amplitude as minimal linear combination of partial amplitudes of the field theory as well as hypergeometric functions. The latter carry the string effects and are analyzed from different perspectives, above all

  8. Evaluación de déficit de atención con hiperactividad: la escala SNAP IV adaptada a la Argentina Assessment of attention deficit hyperactivity: SNAP-IV scale adapted to Argentina

    Directory of Open Access Journals (Sweden)

    Nora Grañana

    2011-05-01

    Full Text Available OBJETIVO: Valorar la utilidad de la escala SNAP IV como instrumento de detección de trastorno por déficit de atención con hiperactividad (TDAH en niños argentinos de 4 a 14 años de edad. MÉTODOS: Se adaptó y se administró la escala SNAP IV a un grupo de 1 230 escolares de la provincia de Buenos Aires, Argentina. Se determinó el diagnóstico con el control clínico de acuerdo a los criterios del Manual diagnóstico y estadístico de los trastornos mentales, 4.ª edición. Se determinaron la sensibilidad y especificidad así como los puntajes de corte para la escala SNAP IV en la población estudiada. RESULTADOS: Se estableció el puntaje en la escala SNAP IV que tuviera la mejor correlación entre sensibilidad y especificidad para determinar los casos verdaderos positivos que realmente tuvieran un diagnóstico clínico. Los puntajes de corte obtenidos fueron: un índice de 1,66 (15/27 puntos para la subescala déficit de atención y de 1,77 (16/27 puntos para hiperactividadimpulsividad en la población estudiada. CONCLUSIONES: La escala SNAP IV para detección de TDAH se considera válida en el caso de la población estudiada, siempre y cuando se modifiquen los puntajes de corte para obtener la mejor relación sensibilidad/especificidad, con base en las particularidades culturales y socioeconómicas de dicha población.OBJECTIVE: Assess the usefulness of the SNAP-IV scale as an instrument for detecting attention deficit hyperactivity disorder (ADHD in Argentine children aged 4 to 14 years. METHODS: The SNAP-IV scale was adapted and administered to a group of 1 230 schoolchildren in the province of Buenos Aires, Argentina. The diagnosis was determined with the clinical control, based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition. The sensitivity and specificity, as well as the cut-off scores for the SNAP-IV scale in the population studied, were determined. RESULTS: The score on the SNAP-IV scale

  9. Direct amplitude detuning measurement with ac dipole

    Directory of Open Access Journals (Sweden)

    S. White

    2013-07-01

    Full Text Available In circular machines, nonlinear dynamics can impact parameters such as beam lifetime and could result in limitations on the performance reach of the accelerator. Assessing and understanding these effects in experiments is essential to confirm the accuracy of the magnetic model and improve the machine performance. A direct measurement of the machine nonlinearities can be obtained by characterizing the dependency of the tune as a function of the amplitude of oscillations (usually defined as amplitude detuning. The conventional technique is to excite the beam to large amplitudes with a single kick and derive the tune from turn-by-turn data acquired with beam position monitors. Although this provides a very precise tune measurement it has the significant disadvantage of being destructive. An alternative, nondestructive way of exciting large amplitude oscillations is to use an ac dipole. The perturbation Hamiltonian in the presence of an ac dipole excitation shows a distinct behavior compared to the free oscillations which should be correctly taken into account in the interpretation of experimental data. The use of an ac dipole for direct amplitude detuning measurement requires careful data processing allowing one to observe the natural tune of the machine; the feasibility of such a measurement is demonstrated using experimental data from the Large Hadron Collider. An experimental proof of the theoretical derivations based on measurements performed at injection energy is provided as well as an application of this technique at top energy using a large number of excitations on the same beam.

  10. Color-Kinematics Duality for QCD Amplitudes

    CERN Document Server

    Johansson, Henrik

    2016-01-01

    We show that color-kinematics duality is present in tree-level amplitudes of quantum chromodynamics with massive flavored quarks. Starting with the color structure of QCD, we work out a new color decomposition for n-point tree amplitudes in a reduced basis of primitive amplitudes. These primitives, with k quark-antiquark pairs and (n-2k) gluons, are taken in the (n-2)!/k! Melia basis, and are independent under the color-algebra Kleiss-Kuijf relations. This generalizes the color decomposition of Del Duca, Dixon, and Maltoni to an arbitrary number of quarks. The color coefficients in the new decomposition are given by compact expressions valid for arbitrary gauge group and representation. Considering the kinematic structure, we show through explicit calculations that color-kinematics duality holds for amplitudes with general configurations of gluons and massive quarks. The new (massive) amplitude relations that follow from the duality can be mapped to a well-defined subset of the familiar BCJ relations for gluo...

  11. Organization of an interphase system for the coupling of WINS-D4 and SNAP-3D programs

    International Nuclear Information System (INIS)

    Frias Suarez, D.

    1989-01-01

    In this report a modular system developed for the CC-1 critical assembly's physical calculation is described. It was based upon the WINS-D4 and SNAP-3D codes, which are coupled by means of an interphase module and a groups diffusion cross sections library

  12. Reproductive physiology in eastern snapping turtles (Chelydra serpentina) exposed to runoff from a concentrated animal feeding operation

    Science.gov (United States)

    The eastern snapping turtle (Chelydra serpentina) is widely distributed throughout the eastern and central U.S. and may be a useful model organism to study land use impacts on water quality. We compared the reproductive condition of C. serpentina from a pond impacted by runoff fr...

  13. Micro-Sugar-Snap and -Wire-Cut Cookie Baking with Trans- and Zero-Trans-Fat Shortenings

    Science.gov (United States)

    The effect of trans- and zero-trans-fat shortenings on cookie-baking performance was evaluated, using the two AACC micro-cookie-baking methods. Regardless of fat type, sugar-snap cookies made with a given flour were larger in diameter, smaller in height, and greater in weight loss during baking tha...

  14. A Study of Structural Stress Technique for Fracture Prediction of an Auto-Mobile Clutch Snap-Ring

    International Nuclear Information System (INIS)

    Kim, Ju Hee; Myeong, Man Sik; Oh, Chang Sik; Kim, Yun Jae

    2016-01-01

    The endurance reliability assessment of a highly complex mechanism is generally predicted by the fatigue life based on simple stress analysis. This study discusses various fatigue life assessment techniques for an automobile clutch snap ring. Finite element analyses were conducted to determine the structural stress on the snap ring. Structural stress that is insensitive in regards to the mesh size and type definition is presented in this study. The structural stress definition is consistent with elementary structural mechanics theory and provides an effective measure of a stress state that pertains to fatigue behavior of welded joints in the form of both membrane and bending components. Numerical procedures for both solid models and shell or plate element models are presented to demonstrate the mesh-size insensitivity when extracting the structural stress parameters. Conventional finite element models can be used with the structural stress calculations as a post-processing procedure. The two major implications from this research were: (a) structural stresses pertaining to fatigue behavior can be consistently calculated in a mesh-insensitive manner regardless of the types of finite element models; and (b) by comparing with the clutch snap-ring fatigue test data, we should predict the fatigue fractures of an automobile clutch snap ring using this method

  15. User’s guide to SNAP for ArcGIS® :ArcGIS interface for scheduling and network analysis program

    Science.gov (United States)

    Woodam Chung; Dennis Dykstra; Fred Bower; Stephen O’Brien; Richard Abt; John. and Sessions

    2012-01-01

    This document introduces a computer software named SNAP for ArcGIS® , which has been developed to streamline scheduling and transportation planning for timber harvest areas. Using modern optimization techniques, it can be used to spatially schedule timber harvest with consideration of harvesting costs, multiple products, alternative...

  16. High energy hadron spin-flip amplitude

    International Nuclear Information System (INIS)

    Selyugin, O.V.

    2016-01-01

    The high-energy part of the hadron spin-flip amplitude is examined in the framework of the new high-energy general structure (HEGS) model of the elastic hadron scattering at high energies. The different forms of the hadron spin-flip amplitude are compared in the impact parameter representation. It is shown that the existing experimental data of the proton-proton and proton-antiproton elastic scattering at high energy in the region of the diffraction minimum and at large momentum transfer give support in the presence of the energy-independent part of the hadron spin-flip amplitude with the momentum dependence proposed in the works by Galynskii-Kuraev. [ru

  17. Scaling of saturation amplitudes in baroclinic instability

    International Nuclear Information System (INIS)

    Shepherd, T.G.

    1994-01-01

    By using finite-amplitude conservation laws for pseudomomentum and pseudoenergy, rigorous upper bounds have been derived on the saturation amplitudes in baroclinic instability for layered and continuously-stratified quasi-geostrophic models. Bounds have been obtained for both the eddy energy and the eddy potential enstrophy. The bounds apply to conservative (inviscid, unforced) flow, as well as to forced-dissipative flow when the dissipation is proportional to the potential vorticity. This approach provides an efficient way of extracting an analytical estimate of the dynamical scalings of the saturation amplitudes in terms of crucial non-dimensional parameters. A possible use is in constructing eddy parameterization schemes for zonally-averaged climate models. The scaling dependences are summarized, and compared with those derived from weakly-nonlinear theory and from baroclinic-adjustment estimates

  18. Analytic representations of Yang–Mills amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Bjerrum-Bohr, N.E.J. [Niels Bohr International Academy and Discovery Center, The Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark); Bourjaily, Jacob L., E-mail: bourjaily@nbi.ku.dk [Niels Bohr International Academy and Discovery Center, The Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark); Damgaard, Poul H. [Niels Bohr International Academy and Discovery Center, The Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark); Feng, Bo [Zhejiang Institute of Modern Physics, Zhejiang University, Hangzhou City, 310027 (China)

    2016-12-15

    Scattering amplitudes in Yang–Mills theory can be represented in the formalism of Cachazo, He and Yuan (CHY) as integrals over an auxiliary projective space—fully localized on the support of the scattering equations. Because solving the scattering equations is difficult and summing over the solutions algebraically complex, a method of directly integrating the terms that appear in this representation has long been sought. We solve this important open problem by first rewriting the terms in a manifestly Möbius-invariant form and then using monodromy relations (inspired by analogy to string theory) to decompose terms into those for which combinatorial rules of integration are known. The result is the foundations of a systematic procedure to obtain analytic, covariant forms of Yang–Mills tree-amplitudes for any number of external legs and in any number of dimensions. As examples, we provide compact analytic expressions for amplitudes involving up to six gluons of arbitrary helicities.

  19. Nonlinear (super)symmetries and amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Kallosh, Renata [Physics Department, Stanford University,382 Via Pueblo Mall, Stanford, CA 94305-4060 (United States)

    2017-03-07

    There is an increasing interest in nonlinear supersymmetries in cosmological model building. Independently, elegant expressions for the all-tree amplitudes in models with nonlinear symmetries, like D3 brane Dirac-Born-Infeld-Volkov-Akulov theory, were recently discovered. Using the generalized background field method we show how, in general, nonlinear symmetries of the action, bosonic and fermionic, constrain amplitudes beyond soft limits. The same identities control, for example, bosonic E{sub 7(7)} scalar sector symmetries as well as the fermionic goldstino symmetries. We present a universal derivation of the vanishing amplitudes in the single (bosonic or fermionic) soft limit. We explain why, universally, the double-soft limit probes the coset space algebra. We also provide identities describing the multiple-soft limit. We discuss loop corrections to N≥5 supergravity, to the D3 brane, and the UV completion of constrained multiplets in string theory.

  20. Scattering Amplitudes and Worldsheet Models of QFTs

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    I will describe recent progress on the study of scattering amplitudes via ambitwistor strings and the scattering equations. Ambitwistor strings are worldsheet models of quantum field theories, inspired by string theory. They naturally lead to a representation of amplitudes based on the scattering equations. While worldsheet models and related ideas have had a wide-ranging impact on the modern study of amplitudes, their direct application at loop level is a very recent success. I will show how a major difficulty in the loop-level story, the technicalities of higher-genus Riemann surfaces, can be avoided by turning the higher-genus surface into a nodal Riemann sphere, with the nodes representing the loop momenta. I will present new formulas for the one-loop integrands of gauge theory and gravity, with or without supersymmetry, and also some two-loop results.

  1. Relativistic amplitudes in terms of wave functions

    International Nuclear Information System (INIS)

    Karmanov, V.A.

    1978-01-01

    In the framework of the invariant diagram technique which arises at the formulation of the fueld theory on the light front the question about conditions at which the relativistic amplitudes may be expressed through the wave functions is investigated. The amplitudes obtained depend on four-vector ω, determining the light front surface. The way is shown to find such values of the four-vector ω, at which the contribution of diagrams not expressed through wave functions is minimal. The investigation carried out is equivalent to the study of the dependence of amplitudes of the old-fashioned perturbation theory in the in the infinite momentum frame on direction of the infinite momentum

  2. Multiphoton amplitude in a constant background field

    Science.gov (United States)

    Ahmad, Aftab; Ahmadiniaz, Naser; Corradini, Olindo; Kim, Sang Pyo; Schubert, Christian

    2018-01-01

    In this contribution, we present our recent compact master formulas for the multiphoton amplitudes of a scalar propagator in a constant background field using the worldline fomulation of quantum field theory. The constant field has been included nonperturbatively, which is crucial for strong external fields. A possible application is the scattering of photons by electrons in a strong magnetic field, a process that has been a subject of great interest since the discovery of astrophysical objects like radio pulsars, which provide evidence that magnetic fields of the order of 1012G are present in nature. The presence of a strong external field leads to a strong deviation from the classical scattering amplitudes. We explicitly work out the Compton scattering amplitude in a magnetic field, which is a process of potential relevance for astrophysics. Our final result is compact and suitable for numerical integration.

  3. Amplitude-modulated fiber-ring laser

    DEFF Research Database (Denmark)

    Caputo, J. G.; Clausen, Carl A. Balslev; Sørensen, Mads Peter

    2000-01-01

    Soliton pulses generated by a fiber-ring laser are investigated by numerical simulation and perturbation methods. The mathematical modeling is based on the nonlinear Schrödinger equation with perturbative terms. We show that active mode locking with an amplitude modulator leads to a self......-starting of stable solitonic pulses from small random noise, provided the modulation depth is small. The perturbative analysis leads to a nonlinear coupled return map for the amplitude, phase, and position of the soliton pulses circulating in the fiber-ring laser. We established the validity of this approach...

  4. Amplitude Models for Discrimination and Yield Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, William Scott [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-01

    This seminar presentation describes amplitude models and yield estimations that look at the data in order to inform legislation. The following points were brought forth in the summary: global models that will predict three-component amplitudes (R-T-Z) were produced; Q models match regional geology; corrected source spectra can be used for discrimination and yield estimation; three-component data increase coverage and reduce scatter in source spectral estimates; three-component efforts must include distance-dependent effects; a community effort on instrument calibration is needed.

  5. Singularity Structure of Maximally Supersymmetric Scattering Amplitudes

    DEFF Research Database (Denmark)

    Arkani-Hamed, Nima; Bourjaily, Jacob L.; Cachazo, Freddy

    2014-01-01

    We present evidence that loop amplitudes in maximally supersymmetric (N=4) Yang-Mills theory (SYM) beyond the planar limit share some of the remarkable structures of the planar theory. In particular, we show that through two loops, the four-particle amplitude in full N=4 SYM has only logarithmic ...... singularities and is free of any poles at infinity—properties closely related to uniform transcendentality and the UV finiteness of the theory. We also briefly comment on implications for maximal (N=8) supergravity theory (SUGRA)....

  6. Amplitude modulation detection with concurrent frequency modulation.

    Science.gov (United States)

    Nagaraj, Naveen K

    2016-09-01

    Human speech consists of concomitant temporal modulations in amplitude and frequency that are crucial for speech perception. In this study, amplitude modulation (AM) detection thresholds were measured for 550 and 5000 Hz carriers with and without concurrent frequency modulation (FM), at AM rates crucial for speech perception. Results indicate that adding 40 Hz FM interferes with AM detection, more so for 5000 Hz carrier and for frequency deviations exceeding the critical bandwidth of the carrier frequency. These findings suggest that future cochlear implant processors, encoding speech fine-structures may consider limiting the FM to narrow bandwidth and to low frequencies.

  7. Gluon amplitudes as 2 d conformal correlators

    Science.gov (United States)

    Pasterski, Sabrina; Shao, Shu-Heng; Strominger, Andrew

    2017-10-01

    Recently, spin-one wave functions in four dimensions that are conformal primaries of the Lorentz group S L (2 ,C ) were constructed. We compute low-point, tree-level gluon scattering amplitudes in the space of these conformal primary wave functions. The answers have the same conformal covariance as correlators of spin-one primaries in a 2 d CFT. The Britto-Cachazo-Feng-Witten (BCFW) recursion relation between three- and four-point gluon amplitudes is recast into this conformal basis.

  8. Precise generator of stability amplitude pulses

    International Nuclear Information System (INIS)

    Zhuk, N.A.; Zdesenko, Yu.G.; Kuts, V.N.

    1989-01-01

    A generator of stability amplitude pulses, designed for stabilization of a low-noise semiconducting spectrometer, used in investigations of 76 Ge2β-decay, is described. The generator contains a permanent-voltage source, a storage element and a switch based on a Hg relay. A thermostatic source provides a relative voltage instability less than ±5x10 -6 per 80h (standard deviation). The Hg relay is placed into a separate thermostat. The relative instability of output generator pulse amplitude does not exceed ±1.5x10 -5 per 24h

  9. High energy multi-gluon exchange amplitudes

    International Nuclear Information System (INIS)

    Jaroszewicz, T.

    1980-11-01

    We examine perturbative high energy n-gluon exchange amplitudes calculated in the Coulomb gauge. If n exceeds the minimum required by the t-channel quantum numbers, such amplitudes are non-leading in lns. We derive a closed system of coupled integral equations for the corresponding two-particle n-gluon vertices, obtained by summing the leading powers of ln(N μ psup(μ)), where psup(μ) is the incident momentum and Nsup(μ) the gauge-defining vector. Our equations are infra-red finite, provided the external particles are colour singlets. (author)

  10. Restructuring a State Nutrition Education and Obesity Prevention Program: Implications of a Local Health Department Model for SNAP-Ed.

    Science.gov (United States)

    Wu, Helen W; Backman, Desiree; Kizer, Kenneth W

    The US Department of Agriculture Supplemental Nutrition Assistance Program-Education (SNAP-Ed) funds state programs to improve nutrition and physical activity in low-income populations through its Nutrition Education and Obesity Prevention grants. States vary in how they manage and structure these programs. California substantially restructured its program in 2012 to universally position local health departments (LHDs) as the programmatic lead in all jurisdictions. This study sought to determine whether California's reorganization aligned with desirable attributes of decentralized public management. This study conducted 40 in person, semistructured interviews with 57 local, state, and federal SNAP-Ed stakeholders between October 2014 and March 2015. Local respondents represented 15 counties in all 7 of California's SNAP-Ed regions. We identified 3 common themes that outlined advantages or disadvantages of local public management, and we further defined subthemes within: (1) coordination and communication (within local jurisdictions, across regions, between local and state), (2) efficiency (administrative, fiscal, program), and (3) quality (innovation, skills). We conducted qualitative content analysis to evaluate how respondents characterized the California experience for each theme, identifying positive and negative experiences. California's LHD model offers some distinct advantages, but the model does not exhibit all the advantages of decentralized public management. Strategic planning, partnerships, subcontracting, and fiscal oversight are closer to communities than previously. However, administrative burden remains high and LHDs are limited in their ability to customize programs on the basis of community needs because of state and federal constraints. California's use of a universal LHD model for SNAP-Ed is novel. Recent federal SNAP-Ed changes present an opportunity for other states to consider this structure. Employing small-scale approaches initially (eg

  11. Amplitude ratios in ρ0 leptoproductions and GPDs

    Directory of Open Access Journals (Sweden)

    Goloskokov S.V.

    2017-01-01

    Using the model results we calculate the ratio of different helicity amplitudes for a transversely polarized proton target to the leading twist longitudinal amplitude. Our results are close to the amplitude ratios measured by HERMES.

  12. Redescription of Dracunculus globocephalus Mackin, 1927 (Nematoda: Dracunculidae), a parasite of the snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Moravec, Frantisek; Little, M D

    2004-12-01

    Dracunculus globocephalus Mackin, 1927 (Nematoda: Dracunculoidea) is redescribed from specimens collected from the mesentery of the snapping turtle, Chelydra serpentina (L.), in Louisiana, USA. The use of scanning electron microscopy, applied for the first time in this species, made it possible to study details in the structure of the cephalic end and the arrangement of male caudal papillae that are difficult to observe under the light microscope. This species markedly differs from all other species of Dracunculus in having the spicules greatly unequal in size and shape, in the absence of a gubernaculum, and in the disposition of male caudal papillae. The validity of D. globocephalus is confirmed, but the above mentioned morphological differences are not sufficient for listing it in a separate genus. This is the first record of D. globocephalus in Louisiana.

  13. Effects of Management Practices on Meloidogyne incognita and Snap Bean Yield.

    Science.gov (United States)

    Smittle, D A; Johnson, A W

    1982-01-01

    Phenamiphos applied at 6.7 kg ai/ha through a solid set or a center pivot irrigation system with 28 mm of water effectively controlled root-knot nematodes, Meloidogyne incognita, and resulted in greater snap bean growth and yields irrespective of growing season, tillage method, or cover crop system. The percentage yield increases attributed to this method of M. incognita control over nontreated controls were 45% in the spring crop, and 90% and 409% in the fall crops following winter rye and fallow, respectively. Root galling was not affected by tillage systems or cover crop, but disk tillage resulted in over 50% reduction in bean yield compared with yields from the subsoil-bed tillage system.

  14. The Schedule for Nonadaptive and Adaptive Personality for Youth (SNAP-Y): a new measure for assessing adolescent personality and personality pathology.

    Science.gov (United States)

    Linde, Jennifer A; Stringer, Deborah; Simms, Leonard J; Clark, Lee Anna

    2013-08-01

    The Schedule for Nonadaptive and Adaptive Personality-Youth Version (SNAP-Y) is a new, reliable self-report questionnaire that assesses 15 personality traits relevant to both normal-range personality and the alternative DSM-5 model for personality disorder. Community adolescents, 12 to 18 years old (N = 364), completed the SNAP-Y; 347 also completed the Big Five Inventory-Adolescent, 144 provided 2-week retest data, and 128 others completed the Minnesota Multiphasic Personality Inventory-Adolescent. Outpatient adolescents (N = 103) completed the SNAP-Y, and 97 also completed the Minnesota Multiphasic Personality Inventory-Adolescent. The SNAP-Y demonstrated strong psychometric properties, and structural, convergent, discriminant, and external validities. Consistent with the continuity of personality, results paralleled those in adult and college samples using the adult Schedule for Nonadaptive and Adaptive Personality-Second Edition (SNAP-2), from which the SNAP-Y derives and which has established validity in personality-trait assessment across the normal-abnormal continuum. The SNAP-Y thus provides a new, clinically useful instrument to assess personality traits and personality pathology in adolescents.

  15. The unhealthy food environment does not modify the association between obesity and participation in the Supplemental Nutrition Assistance Program (SNAP) in Los Angeles County.

    Science.gov (United States)

    Chaparro, M Pia; Harrison, Gail G; Wang, May C; Seto, Edmund Y W; Pebley, Anne R

    2017-01-14

    Participation in the Supplemental Nutrition Assistance Program (SNAP) has been linked to an increased risk of obesity, but not much is known about the mechanisms behind this association. The objective of this study was to determine if the neighborhood density of unhealthy food outlets modifies the association between obesity and participation in SNAP. Data comes from the first wave of the Los Angeles Family and Neighborhood Survey; included are a subsample of adults (18+ years) who were SNAP participants or eligible non-participants (N = 1,176). We carried out multilevel analyses with obesity (BMI ≥ 30 Kg/m 2 ), SNAP participation, and the neighborhood density of unhealthy food outlets as dependent, independent and modifying variables, respectively, controlling for age, gender, race/ethnicity, marital status, working status, mental health, and neighborhood poverty. SNAP participants had double the odds of obesity compared to eligible non-participants (OR = 2.02; 95%CI = 1.44-2.83). However, the neighborhood density of unhealthy food outlets did not modify this association. SNAP participation was associated with higher odds of obesity in our primarily Hispanic sample in Los Angeles County, with no effect modification found for the unhealthy portion of the food environment. More research is needed with additional food environment measures to confirm our null findings. Additional research is needed to elucidate the mechanisms linking SNAP participation and obesity as they remain unclear.

  16. Embryonic hypoxia programmes postprandial cardiovascular function in adult common snapping turtles (Chelydra serpentina).

    Science.gov (United States)

    Wearing, Oliver H; Conner, Justin; Nelson, Derek; Crossley, Janna; Crossley, Dane A

    2017-07-15

    Reduced oxygen availability (hypoxia) is a potent stressor during embryonic development, altering the trajectory of trait maturation and organismal phenotype. We previously documented that chronic embryonic hypoxia has a lasting impact on the metabolic response to feeding in juvenile snapping turtles ( Chelydra serpentina ). Turtles exposed to hypoxia as embryos [10% O 2 (H10)] exhibited an earlier and increased peak postprandial oxygen consumption rate, compared with control turtles [21% O 2 (N21)]. In the current study, we measured central blood flow patterns to determine whether the elevated postprandial metabolic response in H10 turtles is linked to lasting impacts on convective transport. Five years after hatching, turtles were instrumented to quantify systemic ([Formula: see text]) and pulmonary ([Formula: see text]) blood flows and heart rate ( f H ) before and after a ∼5% body mass meal. In adult N21 and H10 turtles, f H was increased significantly by feeding. Although total stroke volume ( V S,tot ) remained at fasted values, this tachycardia contributed to an elevation in total cardiac output ([Formula: see text]). However, there was a postprandial reduction in a net left-right (L-R) shunt in N21 snapping turtles only. Relative to N21 turtles, H10 animals exhibited higher [Formula: see text] due to increased blood flow through the right systemic outflow vessels of the heart. This effect of hypoxic embryonic development, reducing a net L-R cardiac shunt, may support the increased postprandial metabolic rate we previously reported in H10 turtles, and is further demonstration of adult reptile cardiovascular physiology being programmed by embryonic hypoxia. © 2017. Published by The Company of Biologists Ltd.

  17. The establishment of MELCOR/SNAP model of Chinshan nuclear power plant for Ultimate Response Guideline

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Wen-Sheng, E-mail: wshsu@ess.nthu.edu.tw [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Chiang, Yu, E-mail: s101013702@m101.nthu.edu.tw [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Wang, Jong-Rong, E-mail: jongrongwang@gmail.com [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Wang, Ting-Yi, E-mail: minired1119@gmail.com [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Wang, Te-Chuan, E-mail: tcwang@iner.gov.tw [Institute of Nuclear Energy Research Atomic Energy Council, R.O.C., 1000, Wenhua Road Jiaan Village, Longtan Township, Taoyuan County 32546, Taiwan (China); Teng, Jyh-Tong, E-mail: jyhtong@cycu.edu.tw [Department of Mechanical Engineering, Chung Yuan Christian University, 200, Chung Pei Rd, Chung Li 32023, Taiwan, ROC (China); Chen, Shao-Wen, E-mail: chensw@mx.nthu.edu.tw [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); and others

    2017-01-15

    Highlights: • The establishment of a MELCOR/SNAP model of Chinshan (BWR/4). • MELCOR/SNAP model was used to estimate the effectiveness of URG for Chinshan. • The MELCOR results were compared to MAAP, TRACE and PCTRAN. • URG is a new method to prevent a Fukushima-like accident. • The low raw water (150 GPM) can make the cladding temperature below 1088.7 K. - Abstract: After Fukushima Daiichi disaster, the safety analysis of severe accidents became one of the safety concerns in Taiwan. The Emergency Operating Procedure (EOP) cannot cope with a multiple system failure situation under a severe accident since it is a “Symptom-basis” procedure. To deal with that, Taiwan Power Company built up a new strategy for Fukushima-like accident called Ultimate Response Guideline (URG). It is a simple strategy with three main conditions: loss of regular motor driven injection system, loss of all AC power and tsunami/earthquake warning. If two of three happen, the operating procedure will change from EOP to URG and start the main works by following the strategy. There are three main works in URG: controlled-depressurization, line up low pressure injection water and prepare containment venting. In this study, MELCOR2.1 was used to calculate the cases of URG and checked the goal of the strategy that prevents the accident or not. There were three steps in this research. First, a model of Chinshan nuclear power plant (NPP) was built. Second, one was the case with URG and the other was not by using the above MELCOR model. The results were compared to MAAP5.0, TRACE and PCTRAN. Finally, some sensitivity studies of depressurization and water injection rate were done.

  18. Explosion Amplitude Reduction due to Fractures in Water-Saturated and Dry Granite

    Science.gov (United States)

    Stroujkova, A. F.; Leidig, M.; Bonner, J. L.

    2013-12-01

    Empirical observations made at the Semipalatinsk Test Site suggest that nuclear tests in the fracture zones left by previous explosions ('repeat shots') show reduced seismic amplitudes compared to the nuclear tests in virgin rocks. Likely mechanisms for the amplitude reduction in the repeat shots include increased porosity and reduced strength and elastic moduli, leading to pore closing and frictional sliding. Presence of pore water significantly decreases rock compressibility and strength, thus affecting seismic amplitudes. A series of explosion experiments were conducted in order to define the physical mechanism responsible for the amplitude reduction and to quantify the degree of the amplitude reduction in fracture zones of previously detonated explosions. Explosions in water-saturated granite were conducted in central New Hampshire in 2011 and 2012. Additional explosions in dry granite were detonated in Barre, VT in 2013. The amplitude reduction is different between dry and water-saturated crystalline rocks. Significant reduction in seismic amplitudes (by a factor of 2-3) in water-saturated rocks was achieved only when the repeat shot was detonated in the extensive damage zone created by a significantly larger (by a factor of 5) explosion. In case where the first and the second explosions were similar in yield, the amplitude reduction was relatively modest (5-20%). In dry rocks the amplitude reduction reached a factor of 2 even in less extensive damage zones. In addition there are differences in frequency dependence of the spectral amplitude ratios between explosions in dry and water-saturated rocks. Thus the amplitude reduction is sensitive to the extent of the damage zone as well as the pore water content.

  19. Nonlinear analysis of shock absorbers with amplitude-dependent damping

    Science.gov (United States)

    Łuczko, Jan; Ferdek, Urszula; Łatas, Waldemar

    2018-01-01

    This paper contains an analysis of a quarter-car model representing a vehicle equipped with a hydraulic damper whose characteristics are dependent on the piston stroke. The damper, compared to a classical mono-tube damper, has additional internal chambers. Oil flow in those chambers is controlled by relative piston displacement. The proposed nonlinear model of the system is aimed to test the effect of key design parameters of the damper on the quality indices representing ride comfort and driving safety. Numerical methods were used to determine the characteristic curves of the damper and responses of the system to harmonic excitations with their amplitude decreasing as the values of frequency increase.

  20. Stora's fine notion of divergent amplitudes

    Directory of Open Access Journals (Sweden)

    Joseph C. Várilly

    2016-11-01

    Full Text Available Stora and coworkers refined the notion of divergent quantum amplitude, somewhat upsetting the standard power-counting recipe. This unexpectedly clears the way to new prototypes for free and interacting field theories of bosons of any mass and spin.

  1. Connected formulas for amplitudes in standard model

    Energy Technology Data Exchange (ETDEWEB)

    He, Song [CAS Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100190 (China); School of Physical Sciences, University of Chinese Academy of Sciences,No. 19A Yuquan Road, Beijing 100049 (China); Zhang, Yong [Department of Physics, Beijing Normal University,Beijing 100875 (China); CAS Key Laboratory of Theoretical Physics,Institute of Theoretical Physics, Chinese Academy of Sciences,Beijing 100190 (China)

    2017-03-17

    Witten’s twistor string theory has led to new representations of S-matrix in massless QFT as a single object, including Cachazo-He-Yuan formulas in general and connected formulas in four dimensions. As a first step towards more realistic processes of the standard model, we extend the construction to QCD tree amplitudes with massless quarks and those with a Higgs boson. For both cases, we find connected formulas in four dimensions for all multiplicities which are very similar to the one for Yang-Mills amplitudes. The formula for quark-gluon color-ordered amplitudes differs from the pure-gluon case only by a Jacobian factor that depends on flavors and orderings of the quarks. In the formula for Higgs plus multi-parton amplitudes, the massive Higgs boson is effectively described by two additional massless legs which do not appear in the Parke-Taylor factor. The latter also represents the first twistor-string/connected formula for form factors.

  2. Fatigue Reliability under Multiple-Amplitude Loads

    DEFF Research Database (Denmark)

    Talreja, R.

    1979-01-01

    for the initial tensile strength and the fatigue life, the probability distributions for the residual tensile strength in both the crack initiation and the crack propagation stages of fatigue are determined. The method is illustrated for two-amplitude loads by means of experimental results obtained by testing...

  3. Ward identities for amplitudes with reggeized gluons

    International Nuclear Information System (INIS)

    Bartles, J.; Vacca, G.P.

    2012-05-01

    Starting from the effective action of high energy QCD we derive Ward identities for Green's functions of reggeized gluons. They follow from the gauge invariance of the effective action, and allow to derive new representations of amplitudes containing physical particles as well as reggeized gluons. We explicitly demonstrate their validity for the BFKL kernel, and we present a new derivation of the kernel.

  4. Scattering amplitudes in super-renormalizable gravity

    International Nuclear Information System (INIS)

    Donà, Pietro; Giaccari, Stefano; Modesto, Leonardo; Rachwał, Lesław; Zhu, Yiwei

    2015-01-01

    We explicitly compute the tree-level on-shell four-graviton amplitudes in four, five and six dimensions for local and weakly nonlocal gravitational theories that are quadratic in both, the Ricci and scalar curvature with form factors of the d’Alembertian operator inserted between. More specifically we are interested in renormalizable, super-renormalizable or finite theories. The scattering amplitudes for these theories turn out to be the same as the ones of Einstein gravity regardless of the explicit form of the form factors. As a special case the four-graviton scattering amplitudes in Weyl conformal gravity are identically zero. Using a field redefinition, we prove that the outcome is correct for any number of external gravitons (on-shell n−point functions) and in any dimension for a large class of theories. However, when an operator quadratic in the Riemann tensor is added in any dimension (with the exception of the Gauss-Bonnet term in four dimensions) the result is completely altered, and the scattering amplitudes depend on all the form factors introduced in the action.

  5. Particle Distribution Modification by Low Amplitude Modes

    International Nuclear Information System (INIS)

    White, R.B.; Gorelenkov, N.; Heidbrink, W.W.; Van Zeeland, M.A.

    2009-01-01

    Modification of a high energy particle distribution by a spectrum of low amplitude modes is investigated using a guiding center code. Only through resonance are modes effective in modifying the distribution. Diagnostics are used to illustrate the mode-particle interaction and to find which effects are relevant in producing significant resonance, including kinetic Poincare plots and plots showing those orbits with time averaged mode-particle energy transfer. Effects of pitch angle scattering and drag are studied, as well as plasma rotation and time dependence of the equilibrium and mode frequencies. A specific example of changes observed in a DIII-D deuterium beam distribution in the presence of low amplitude experimentally validated Toroidal Alfven (TAE) eigenmodes and Reversed Shear Alfven (RSAE) eigenmodes is examined in detail. Comparison with experimental data shows that multiple low amplitude modes can account for significant modification of high energy beam particle distributions. It is found that there is a stochastic threshold for beam profile modification, and that the experimental amplitudes are only slightly above this threshold.

  6. Kaon decay amplitudes using staggered fermions

    International Nuclear Information System (INIS)

    Sharpe, S.R.

    1986-12-01

    A status report is given of an attempt, using staggered fermions to calculate the real and imaginary parts of the amplitudes for K → ππ,. Semi-quantitative results are found for the imaginary parts, and these suggest that ε' might be smaller than previously expected in the standard model

  7. Constraints on low energy Compton scattering amplitudes

    International Nuclear Information System (INIS)

    Raszillier, I.

    1979-04-01

    We derive the constraints and correlations of fairly general type for Compton scattering amplitudes at energies below photoproduction threshold and fixed momentum transfer, following from (an upper bound on) the corresponding differential cross section above photoproduction threshold. The derivation involves the solution of an extremal problem in a certain space of vector - valued analytic functions. (author)

  8. Analytic properties of many-particle amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Medvedev, B V; Pavlov, V P; Polivanov, M K; Sukhanov, A D [Gosudarstvennyj Komitet po Ispol' zovaniyu Atomnoj Ehnergii SSSR, Moscow. Inst. Teoreticheskoj i Ehksperimental' noj Fiziki; AN SSSR, Moscow. Matematicheskij Inst.)

    1982-08-01

    In the framework of N. N. Bogolyubov axiomatic approach the complete proof of the existence of an analytic function the boundary values of which are the amplitudes of any channel of n-particle process is given. The one-particle structure of this function is described.

  9. Vlasov simulation of the relativistic effect on the breaking of large amplitude plasma waves

    International Nuclear Information System (INIS)

    Xu Hui; Sheng Zhengming; Zhang Jie

    2007-01-01

    The influence of relativistic and thermal effects on plasma wave breaking has been studied by solving the coupled Vlasov-Poisson equations. When the relativistic effect is not considered, the wave breaking will not occur, provided the initial perturbation is less than certain value as predicted previously, and the largest amplitude of the plasma wave will decrease with the increase of the initial temperature. When the relativistic effect is considered, wave breaking always occurs during the time evolution, irrespective of the initial perturbation amplitude. Yet the smaller the initial perturbation amplitude is, the longer is the time for wave breaking to occur. With large initial perturbations, wave breaking can always occur with the without the relativistic effect. However, the results are significantly different in the two cases. The thermal effects of electrons decrease the threshold value to initial amplitude for wave breaking and large phase velocity makes the nonlinear phenomenon occur more easily. (authors)

  10. Coupling dynamics in speech gestures: amplitude and rate influences.

    Science.gov (United States)

    van Lieshout, Pascal H H M

    2017-08-01

    Speech is a complex oral motor function that involves multiple articulators that need to be coordinated in space and time at relatively high movement speeds. How this is accomplished remains an important and largely unresolved empirical question. From a coordination dynamics perspective, coordination involves the assembly of coordinative units that are characterized by inherently stable coupling patterns that act as attractor states for task-specific actions. In the motor control literature, one particular model formulated by Haken et al. (Biol Cybern 51(5):347-356, 1985) or HKB has received considerable attention in the way it can account for changes in the nature and stability of specific coordination patterns between limbs or between limbs and external stimuli. In this model (and related versions), movement amplitude is considered a critical factor in the formation of these patterns. Several studies have demonstrated its role for bimanual coordination and similar types of tasks, but for speech motor control such studies are lacking. The current study describes a systematic approach to evaluate the impact of movement amplitude and movement duration on coordination stability in the production of bilabial and tongue body gestures for specific vowel-consonant-vowel strings. The vowel combinations that were used induced a natural contrast in movement amplitude at three speaking rate conditions (slow, habitual, fast). Data were collected on ten young adults using electromagnetic articulography, recording movement data from lips and tongue with high temporal and spatial precision. The results showed that with small movement amplitudes there is a decrease in coordination stability, independent from movement duration. These findings were found to be robust across all individuals and are interpreted as further evidence that principles of coupling dynamics operate in the oral motor control system similar to other motor systems and can be explained in terms of coupling

  11. Cascaded Amplitude Modulations in Sound Texture Perception

    DEFF Research Database (Denmark)

    McWalter, Richard Ian; Dau, Torsten

    2017-01-01

    . In this study, we investigated the perception of sound textures that contain rhythmic structure, specifically second-order amplitude modulations that arise from the interaction of different modulation rates, previously described as "beating" in the envelope-frequency domain. We developed an auditory texture...... model that utilizes a cascade of modulation filterbanks that capture the structure of simple rhythmic patterns. The model was examined in a series of psychophysical listening experiments using synthetic sound textures-stimuli generated using time-averaged statistics measured from real-world textures....... In a texture identification task, our results indicated that second-order amplitude modulation sensitivity enhanced recognition. Next, we examined the contribution of the second-order modulation analysis in a preference task, where the proposed auditory texture model was preferred over a range of model...

  12. Source amplitudes for active exterior cloaking

    International Nuclear Information System (INIS)

    Norris, Andrew N; Amirkulova, Feruza A; Parnell, William J

    2012-01-01

    The active cloak comprises a discrete set of multipole sources that destructively interfere with an incident time harmonic scalar wave to produce zero total field over a finite spatial region. For a given number of sources and their positions in two dimensions it is shown that the multipole amplitudes can be expressed as infinite sums of the coefficients of the incident wave decomposed into regular Bessel functions. The field generated by the active sources vanishes in the infinite region exterior to a set of circles defined by the relative positions of the sources. The results provide a direct solution to the inverse problem of determining the source amplitudes. They also define a broad class of non-radiating discrete sources. (paper)

  13. Constructing QCD one-loop amplitudes

    International Nuclear Information System (INIS)

    Forde, D

    2008-01-01

    In the context of constructing one-loop amplitudes using a unitarity bootstrap approach we discuss a general systematic procedure for obtaining the coefficients of the scalar bubble and triangle integral functions of one-loop amplitudes. Coefficients are extracted after examining the behavior of the cut integrand as the unconstrained parameters of a specifically chosen parameterization of the cut loop momentum approach infinity. Measurements of new physics at the forthcoming experimental program at CERN's Large Hadron Collider (LHC) will require a precise understanding of processes at next-to-leading order (NLO). This places increased demands for the computation of new one-loop amplitudes. This in turn has spurred recent developments towards improved calculational techniques. Direct calculations using Feynman diagrams are in general inefficient. Developments of more efficient techniques have usually centered around unitarity techniques [1], where tree amplitudes are effectively 'glued' together to form loops. The most straightforward application of this method, in which the cut loop momentum is in D = 4, allows for the computation of 'cut-constructible' terms only, i.e. (poly)logarithmic containing terms and any related constants. QCD amplitudes contain, in addition to such terms, rational pieces which cannot be derived using such cuts. These 'missing' rational parts can be extracted using cut loop momenta in D = 4-2 (var e psilon). The greater difficulty of such calculations has restricted the application of this approach, although recent developments [3, 4] have provided new promise for this technique. Recently the application of on-shell recursion relations [5] to obtaining the 'missing' rational parts of one-loop processes [6] has provided an alternative very promising solution to this problem. In combination with unitarity methods an 'on-shell bootstrap' approach provides an efficient technique for computing complete one-loop QCD amplitudes [7]. Additionally

  14. Differential equations, associators, and recurrences for amplitudes

    Directory of Open Access Journals (Sweden)

    Georg Puhlfürst

    2016-01-01

    Full Text Available We provide new methods to straightforwardly obtain compact and analytic expressions for ϵ-expansions of functions appearing in both field and string theory amplitudes. An algebraic method is presented to explicitly solve for recurrence relations connecting different ϵ-orders of a power series solution in ϵ of a differential equation. This strategy generalizes the usual iteration by Picard's method. Our tools are demonstrated for generalized hypergeometric functions. Furthermore, we match the ϵ-expansion of specific generalized hypergeometric functions with the underlying Drinfeld associator with proper Lie algebra and monodromy representations. We also apply our tools for computing ϵ-expansions for solutions to generic first-order Fuchsian equations (Schlesinger system. Finally, we set up our methods to systematically get compact and explicit α′-expansions of tree-level superstring amplitudes to any order in α′.

  15. Unitarity and amplitudes for high energies

    International Nuclear Information System (INIS)

    Efimov, G.V.

    1997-01-01

    It is shown that in the quantum field theory of scalar particles with mass m the following inequalities for the upper bound for the amplitude of elastic scattering Μ(s,t) |Μ(s,t)| 0 )s, (|t|≥|t 0 |>0) and for the total cross section of scalar particles σ tot (s)≤C|d/dt ln Im Μ(s,t)| t=0 , (s → ∞) are valid. This result is based on the unitarity of the S-matrix on the mass shell and on a natural assumption that the imaginary part of the elastic scattering Im Μ(s,t) is a differentiable and convex down function in some vicinity of t=0. The locality of the theory and the analyticity of the elastic amplitude in the Martin-Lehmann ellipse are not used in proving these inequalities

  16. Large amplitude waves and fields in plasmas

    International Nuclear Information System (INIS)

    Angelis, U. de; Naples Univ.

    1990-02-01

    In this review, based mostly on the results of the recent workshop on ''Large Amplitude Waves and Fields in Plasmas'' held at ICTP (Trieste, Italy) in May 1989 during the Spring College on Plasma Physics, I will mostly concentrate on underdense, cold, homogeneous plasmas, discussing some of the alternative (to fusion) uses of laser-plasma interaction. In Part I an outline of some basic non-linear processes is given, together with some recent experimental results. The processes are chosen because of their relevance to the applications or because new interesting developments have been reported at the ICTP workshop (or both). In Part II the excitation mechanisms and uses of large amplitude plasma waves are presented: these include phase-conjugation in plasmas, plasma based accelerators (beat-wave, plasma wake-field and laser wake-field), plasma lenses and plasma wigglers for Free Electron Lasers. (author)

  17. Integrable spin chains and scattering amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Bartels, J.; Prygarin, A. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Lipatov, L.N. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Petersburg Nuclear Physics Institute (Russian Federation); Sankt-Peterburgskij Univ., St. Petersburg (Russian Federation)

    2011-04-15

    In this review we show that the multi-particle scattering amplitudes in N=4 SYM at large N{sub c} and in the multi-Regge kinematics for some physical regions have the high energy behavior appearing from the contribution of the Mandelstam cuts in the complex angular momentum plane of the corresponding t-channel partial waves. These Mandelstam cuts or Regge cuts are resulting from gluon composite states in the adjoint representation of the gauge group SU(N{sub c}). In the leading logarithmic approximation (LLA) their contribution to the six point amplitude is in full agreement with the known two-loop result. The Hamiltonian for the Mandelstam states constructed from n gluons in LLA coincides with the local Hamiltonian of an integrable open spin chain. We construct the corresponding wave functions using the integrals of motion and the Baxter-Sklyanin approach. (orig.)

  18. Understanding the amplitudes of noise correlation measurements

    Science.gov (United States)

    Tsai, Victor C.

    2011-01-01

    Cross correlation of ambient seismic noise is known to result in time series from which station-station travel-time measurements can be made. Part of the reason that these cross-correlation travel-time measurements are reliable is that there exists a theoretical framework that quantifies how these travel times depend on the features of the ambient noise. However, corresponding theoretical results do not currently exist to describe how the amplitudes of the cross correlation depend on such features. For example, currently it is not possible to take a given distribution of noise sources and calculate the cross correlation amplitudes one would expect from such a distribution. Here, we provide a ray-theoretical framework for calculating cross correlations. This framework differs from previous work in that it explicitly accounts for attenuation as well as the spatial distribution of sources and therefore can address the issue of quantifying amplitudes in noise correlation measurements. After introducing the general framework, we apply it to two specific problems. First, we show that we can quantify the amplitudes of coherency measurements, and find that the decay of coherency with station-station spacing depends crucially on the distribution of noise sources. We suggest that researchers interested in performing attenuation measurements from noise coherency should first determine how the dominant sources of noise are distributed. Second, we show that we can quantify the signal-to-noise ratio of noise correlations more precisely than previous work, and that these signal-to-noise ratios can be estimated for given situations prior to the deployment of seismometers. It is expected that there are applications of the theoretical framework beyond the two specific cases considered, but these applications await future work.

  19. On the infinities of closed superstring amplitudes

    International Nuclear Information System (INIS)

    Restuccia, A.; Taylor, J.G.

    1988-01-01

    The authors present an analysis of possible infinities that may be present in uncompactified multi-loop heterotic and type II superstring amplitudes constructed, without use of the short-string limit, in the light-cone gauge, and with use of a closed [10]-SUSY field theory algebra. Various types of degenerations of the integrand are discussed on the string worldsheet. No infinities are found, modulo (for type II) a particular identity for Green's functions

  20. Deep Inelastic Scattering at the Amplitude Level

    International Nuclear Information System (INIS)

    Brodsky, Stanley J.

    2005-01-01

    The deep inelastic lepton scattering and deeply virtual Compton scattering cross sections can be interpreted in terms of the fundamental wavefunctions defined by the light-front Fock expansion, thus allowing tests of QCD at the amplitude level. The AdS/CFT correspondence between gauge theory and string theory provides remarkable new insights into QCD, including a model for hadronic wavefunctions which display conformal scaling at short distances and color confinement at large distances

  1. Multichannel conformal blocks for scattering amplitudes

    Science.gov (United States)

    Belitsky, A. V.

    2018-05-01

    By performing resummation of small fermion-antifermion pairs within the pentagon form factor program to scattering amplitudes in planar N = 4 superYang-Mills theory, we construct multichannel conformal blocks within the flux-tube picture for N-sided NMHV polygons. This procedure is equivalent to summation of descendants of conformal primaries in the OPE framework. The resulting conformal partial waves are determined by multivariable hypergeometric series of Lauricella-Saran type.

  2. How to calculate the Coulomb scattering amplitude

    International Nuclear Information System (INIS)

    Grosse, H.; Narnhofer, H.; Thirring, W.

    1974-01-01

    The derivation of scattering amplitudes for Coulomb scattering is discussed. A derivation of the S-matrix elements for a dense set of states in momentum space is given in the framework of time dependent scattering theory. The convergence of the S-matrix is studied. A purely algebraic derivation of the S-matrix elements and phase shifts is also presented. (HFdV)

  3. Scattering amplitudes from multivariate polynomial division

    Energy Technology Data Exchange (ETDEWEB)

    Mastrolia, Pierpaolo, E-mail: pierpaolo.mastrolia@cern.ch [Max-Planck-Institut fuer Physik, Foehringer Ring 6, 80805 Muenchen (Germany); Dipartimento di Fisica e Astronomia, Universita di Padova, Padova (Italy); INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Mirabella, Edoardo, E-mail: mirabell@mppmu.mpg.de [Max-Planck-Institut fuer Physik, Foehringer Ring 6, 80805 Muenchen (Germany); Ossola, Giovanni, E-mail: GOssola@citytech.cuny.edu [New York City College of Technology, City University of New York, 300 Jay Street, Brooklyn, NY 11201 (United States); Graduate School and University Center, City University of New York, 365 Fifth Avenue, New York, NY 10016 (United States); Peraro, Tiziano, E-mail: peraro@mppmu.mpg.de [Max-Planck-Institut fuer Physik, Foehringer Ring 6, 80805 Muenchen (Germany)

    2012-11-15

    We show that the evaluation of scattering amplitudes can be formulated as a problem of multivariate polynomial division, with the components of the integration-momenta as indeterminates. We present a recurrence relation which, independently of the number of loops, leads to the multi-particle pole decomposition of the integrands of the scattering amplitudes. The recursive algorithm is based on the weak Nullstellensatz theorem and on the division modulo the Groebner basis associated to all possible multi-particle cuts. We apply it to dimensionally regulated one-loop amplitudes, recovering the well-known integrand-decomposition formula. Finally, we focus on the maximum-cut, defined as a system of on-shell conditions constraining the components of all the integration-momenta. By means of the Finiteness Theorem and of the Shape Lemma, we prove that the residue at the maximum-cut is parametrized by a number of coefficients equal to the number of solutions of the cut itself.

  4. Cascaded Amplitude Modulations in Sound Texture Perception

    Directory of Open Access Journals (Sweden)

    Richard McWalter

    2017-09-01

    Full Text Available Sound textures, such as crackling fire or chirping crickets, represent a broad class of sounds defined by their homogeneous temporal structure. It has been suggested that the perception of texture is mediated by time-averaged summary statistics measured from early auditory representations. In this study, we investigated the perception of sound textures that contain rhythmic structure, specifically second-order amplitude modulations that arise from the interaction of different modulation rates, previously described as “beating” in the envelope-frequency domain. We developed an auditory texture model that utilizes a cascade of modulation filterbanks that capture the structure of simple rhythmic patterns. The model was examined in a series of psychophysical listening experiments using synthetic sound textures—stimuli generated using time-averaged statistics measured from real-world textures. In a texture identification task, our results indicated that second-order amplitude modulation sensitivity enhanced recognition. Next, we examined the contribution of the second-order modulation analysis in a preference task, where the proposed auditory texture model was preferred over a range of model deviants that lacked second-order modulation rate sensitivity. Lastly, the discriminability of textures that included second-order amplitude modulations appeared to be perceived using a time-averaging process. Overall, our results demonstrate that the inclusion of second-order modulation analysis generates improvements in the perceived quality of synthetic textures compared to the first-order modulation analysis considered in previous approaches.

  5. Transversity Amplitudes in Hypercharge Exchange Processes

    International Nuclear Information System (INIS)

    Aguilar Benitez de Lugo, M.

    1979-01-01

    ' In this work we present several techniques developed for the extraction of the. Transversity amplitudes governing quasi two-body meson baryon reactions with hypercharge exchange. We review the methods used in processes having a pure spin configuration, as well as the more relevant results obtained with data from K p and Tp interactions at intermediate energies. The predictions of the additive quark model and the ones following from exchange degeneracy and etoxicity are discussed. We present a formalism for amplitude analysis developed for reactions with mixed spin configurations and discuss the methods of parametric estimation of the moduli and phases of the amplitudes, as well as the various tests employed to check the goodness of the fits. The calculation of the generalized joint density matrices is given and we propose a method based on the generalization of the idea of multipole moments, which allows to investigate the structure of the decay angular correlations and establishes the quality of the fits and the validity of the simplifying assumptions currently used in this type of studies. (Author) 43 refs

  6. The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes

    DEFF Research Database (Denmark)

    Boström, Pontus; Andersson, Linda; Vind, Birgitte

    2010-01-01

    /cytosolic compartment in the patients with the type 2 diabetes. Expression of the SNARE-interacting protein Munc18c was higher in skeletal muscle from patients with type 2 diabetes. Studies in L6 cells showed that Munc18c promoted the expression of SNAP23. CONCLUSIONS: We have translated our previous in vitro results......OBJECTIVE: Our previous studies suggest that the SNARE protein synaptosomal-associated protein of 23 kDa (SNAP23) is involved in the link between increased lipid levels and insulin resistance in cardiomyocytes. The objective was to determine whether SNAP23 may also be involved in the known...... association between lipid accumulation in skeletal muscle and insulin resistance/type 2 diabetes in humans, as well as to identify a potential regulator of SNAP23. RESEARCH DESIGN AND METHODS: We analyzed skeletal muscle biopsies from patients with type 2 diabetes and healthy, insulin-sensitive control...

  7. Touching lips and hearing fingers: effector-specific congruency between tactile and auditory stimulation modulates N1 amplitude and alpha desynchronization.

    Science.gov (United States)

    Shen, Guannan; Meltzoff, Andrew N; Marshall, Peter J

    2018-01-01

    Understanding the interactions between audition and sensorimotor processes is of theoretical importance, particularly in relation to speech processing. Although one current focus in this area is on interactions between auditory perception and the motor system, there has been less research on connections between the auditory and somatosensory modalities. The current study takes a novel approach to this omission by examining specific auditory-tactile interactions in the context of speech and non-speech sound production. Electroencephalography was used to examine brain responses when participants were presented with speech syllables (a bilabial sound /pa/ and a non-labial sound /ka/) or finger-snapping sounds that were simultaneously paired with tactile stimulation of either the lower lip or the right middle finger. Analyses focused on the sensory-evoked N1 in the event-related potential and the extent of alpha band desynchronization elicited by the stimuli. N1 amplitude over fronto-central sites was significantly enhanced when the bilabial /pa/ sound was paired with tactile lip stimulation and when the finger-snapping sound was paired with tactile stimulation of the finger. Post-stimulus alpha desynchronization at central sites was also enhanced when the /pa/ sound was accompanied by tactile stimulation of the lip. These novel findings indicate that neural aspects of somatosensory-auditory interactions are influenced by the congruency between the location of the bodily touch and the bodily origin of a perceived sound.

  8. Investigating the amplitude of interactive footstep sounds and soundscape reproduction

    DEFF Research Database (Denmark)

    Turchet, Luca; Serafin, Stefania

    2013-01-01

    In this paper, we study the perception of amplitude of soundscapes and interactively generated footstep sounds provided both through headphones and a surround sound system. In particular, we investigate whether there exists a value for the amplitude of soundscapes and footstep sounds which...... of soundscapes does not significantly affect the selected amplitude of footstep sounds. Similarly, the perception of the soundscapes amplitude is not significantly affected by the selected amplitude of footstep sounds....

  9. One-loop triple collinear splitting amplitudes in QCD

    Energy Technology Data Exchange (ETDEWEB)

    Badger, Simon; Buciuni, Francesco; Peraro, Tiziano [Higgs Centre for Theoretical Physics, School of Physics and Astronomy, University of Edinburgh,Edinburgh EH9 3JZ, Scotland (United Kingdom)

    2015-09-28

    We study the factorisation properties of one-loop scattering amplitudes in the triple collinear limit and extract the universal splitting amplitudes for processes initiated by a gluon. The splitting amplitudes are derived from the analytic Higgs plus four partons amplitudes. We present compact results for primitive helicity splitting amplitudes making use of super-symmetric decompositions. The universality of the collinear factorisation is checked numerically against the full colour six parton squared matrix elements.

  10. Creating a business toolbox for a start-up : a case study of SnapSwap International

    OpenAIRE

    Kovshikov, Iaroslav

    2017-01-01

    This thesis was implemented at SnapSwap International in spring and summer 2017. The case company is a fin-tech start-up established in 2015 and located in Luxembourg. The company aims to develop a new payment solution (money messenger) for the European market. The purpose of the thesis is to observe commonly used business techniques (SWOT, Business Model Canvas (BMC), Persona, and Empathy Map) and analyze current business activities of the company employing these tools. The theoretic...

  11. Insecticide Efficacy and Timing for Control of Western Bean Cutworm (Lepidoptera: Noctuidae) in Dry and Snap Beans.

    Science.gov (United States)

    Goudis, L A; Trueman, C L; Baute, T S; Hallett, R H; Gillard, C L

    2016-02-01

    The western bean cutworm, Striacosta albicosta (Smith) (Lepidoptera: Noctuidae), is a recent pest of corn, dry,and snap beans, in the Great Lakes region, and best practices for its management in beans need to be established.Insecticide efficacy and application timing field studies, conducted in 2011–2013, determined that lambda-cyhalothrin and chlorantraniliprole were capable of reducing western bean cutworm feeding damage in dry beans from 2.3 to 0.4% in preharvest samples, and in snap beans from 4.8 to 0.1% of marketable pods, respectively. The best application timing in dry beans was determined to be 4–18 d after 50% egg hatch. No economic benefit was found when products were applied to dry beans, and despite high artificial inoculation rates, damage to marketable yield was relatively low. Thiamethoxam, methoxyfenozide, and spinetoram were also found to be effective at reducing western bean cutworm damage in dry bean to as low as 0.3% compared to an untreated control with 2.5% damaged pods. In snap beans, increased return on investment between CAD$400 and CAD$600 was seen with multiple applications of lambda-cyhalothrin, and with chlorantraniliprole applied 4 d after egg mass infestation.

  12. Experimental investigation of snap-through motion of in-plane MEMS shallow arches under electrostatic excitation

    KAUST Repository

    Ramini, Abdallah

    2015-12-11

    We present an experimental investigation for the nonlinear dynamic behaviors of clamped–clamped in-plane MEMS shallow arches when excited by harmonic electrostatic forces. Frequency sweeps are conducted to study the dynamic behaviors in the neighborhoods of the first and third resonance frequencies as well as the super-harmonic resonances. Experimental results show local softening behavior of small oscillations around the first resonance frequency and hardening behavior at the third resonance frequency for small dc and ac loads. Interesting dynamic snap-through cross-well motions are observed experimentally at high voltages for the first time in the micro-scale world. In addition to the dynamic snap-through motion, the MEMS arch exhibits large oscillations of a continuous band of snap-through motion between the super-harmonic resonance regime and the first primary resonance regime. This continuous band is unprecedented experimentally in the micro/macro world, and is promising for a variety of sensing, actuation and communications applications.

  13. Experimental investigation of snap-through motion of in-plane MEMS shallow arches under electrostatic excitation

    KAUST Repository

    Ramini, Abdallah; Bellaredj, Mohammed L F; Al Hafiz, Md Abdullah; Younis, Mohammad I.

    2015-01-01

    We present an experimental investigation for the nonlinear dynamic behaviors of clamped–clamped in-plane MEMS shallow arches when excited by harmonic electrostatic forces. Frequency sweeps are conducted to study the dynamic behaviors in the neighborhoods of the first and third resonance frequencies as well as the super-harmonic resonances. Experimental results show local softening behavior of small oscillations around the first resonance frequency and hardening behavior at the third resonance frequency for small dc and ac loads. Interesting dynamic snap-through cross-well motions are observed experimentally at high voltages for the first time in the micro-scale world. In addition to the dynamic snap-through motion, the MEMS arch exhibits large oscillations of a continuous band of snap-through motion between the super-harmonic resonance regime and the first primary resonance regime. This continuous band is unprecedented experimentally in the micro/macro world, and is promising for a variety of sensing, actuation and communications applications.

  14. Research to Understand Milk Consumption Behaviors in a Food-Insecure Low-Income SNAP Population in the US

    Directory of Open Access Journals (Sweden)

    Karla Jaye Finnell

    2017-09-01

    Full Text Available Milk, due to its affordability and nutritional value, can fortify the diets of families that experience food insecurity or find a high-quality diet cost-prohibitive. However, it can also be a leading source of excess calories and saturated fat. Yet, little is known about what influences consumer behavior of Supplemental Nutrition Assistance Program (SNAP recipients toward the type of milk used or the prevalence of low-fat milk use among this population. This cross-sectional telephone survey of SNAP recipients (n = 520 documented that 7.5% of this population usually consumes low-fat milk, a prevalence that lags behind national figures (34.4% for the same time-period. There was a weak association between sociodemographic characteristics of SNAP recipients and low-fat milk use. Instead, less low-fat milk consumption was associated with a knowledge gap and misperceptions of the nutritional properties of the different types of milk. Promoting low-fat milk use by correcting these misperceptions can improve the diet of America’s low-income population and reduce food insecurity by maximizing the nutritional value of the foods consumed.

  15. Dynamics of snap-off and pore-filling events during two-phase fluid flow in permeable media.

    Science.gov (United States)

    Singh, Kamaljit; Menke, Hannah; Andrew, Matthew; Lin, Qingyang; Rau, Christoph; Blunt, Martin J; Bijeljic, Branko

    2017-07-12

    Understanding the pore-scale dynamics of two-phase fluid flow in permeable media is important in many processes such as water infiltration in soils, oil recovery, and geo-sequestration of CO 2 . The two most important processes that compete during the displacement of a non-wetting fluid by a wetting fluid are pore-filling or piston-like displacement and snap-off; this latter process can lead to trapping of the non-wetting phase. We present a three-dimensional dynamic visualization study using fast synchrotron X-ray micro-tomography to provide new insights into these processes by conducting a time-resolved pore-by-pore analysis of the local curvature and capillary pressure. We show that the time-scales of interface movement and brine layer swelling leading to snap-off are several minutes, orders of magnitude slower than observed for Haines jumps in drainage. The local capillary pressure increases rapidly after snap-off as the trapped phase finds a position that is a new local energy minimum. However, the pressure change is less dramatic than that observed during drainage. We also show that the brine-oil interface jumps from pore-to-pore during imbibition at an approximately constant local capillary pressure, with an event size of the order of an average pore size, again much smaller than the large bursts seen during drainage.

  16. Subacute casemix classification for stroke rehabilitation in Australia. How well does AN-SNAP v2 explain variance in outcomes?

    Science.gov (United States)

    Kohler, Friedbert; Renton, Roger; Dickson, Hugh G; Estell, John; Connolly, Carol E

    2011-02-01

    We sought the best predictors for length of stay, discharge destination and functional improvement for inpatients undergoing rehabilitation following a stroke and compared these predictors against AN-SNAP v2. The Oxfordshire classification subgroup, sociodemographic data and functional data were collected for patients admitted between 1997 and 2007, with a diagnosis of recent stroke. The data were factor analysed using Principal Components Analysis for categorical data (CATPCA). Categorical regression analyses was performed to determine the best predictors of length of stay, discharge destination, and functional improvement. A total of 1154 patients were included in the study. Principal components analysis indicated that the data were effectively unidimensional, with length of stay being the most important component. Regression analysis demonstrated that the best predictor was the admission motor FIM score, explaining 38.9% of variance for length of stay, 37.4%.of variance for functional improvement and 16% of variance for discharge destination. The best explanatory variable in our inpatient rehabilitation service is the admission motor FIM. AN- SNAP v2 classification is a less effective explanatory variable. This needs to be taken into account when using AN-SNAP v2 classification for clinical or funding purposes.

  17. Modelling and mitigation of wheel squeal noise amplitude

    Science.gov (United States)

    Meehan, Paul A.; Liu, Xiaogang

    2018-01-01

    The prediction of vibration amplitude and sound pressure level of wheel squeal noise is investigated using a concise mathematical model that is verified with measurements from both a rolling contact two disk test rig and a field case study. The model is used to perform an energy-based analysis to determine a closed form solution to the steady state limit cycle amplitude of creep and vibration oscillations during squealing. The analytical solution compares well with a numerical solution using an experimentally tuned creep curve with full nonlinear shape. The predicted squeal sound level trend also compares well with that recorded at various crabbing velocities (proportional to angle of attack) for the test rig at different rolling speeds. In addition, further verification is performed against many field recordings of wheel squeal on a sharp curve of 300 m. A comparison with a simplified modified result from Rudd [1] is also provided and highlights the accuracy and advantages of the present efficient model. The analytical solution provides insight into why the sound pressure level of squeal noise increases with crabbing velocity (or angle of attack) as well as how the amplitude is affected by the critical squeal parameters including a detailed investigation of modal damping. Finally, the efficient model is used to perform a parametric investigation into means of achieving a 6 dB decrease in squeal noise. The results highlight the primary importance of crabbing velocity (and angle of attack) as well as the creep curve parameters that may be controlled using third body control (ie friction modifiers). The results concur with experimental and field observations and provide important theoretical insight into the useful mechanisms of mitigating wheel squeal and quantifying their relative merits.

  18. Ethnic differences in electrocardiographic amplitude measurements

    International Nuclear Information System (INIS)

    Mansi, Ishak A.; Nash, Ira S.

    2004-01-01

    There is a controversy regarding ethnic differences in electrocardiographic (ECG) patterns because of the potentially confounding socioeconomic, nutritional, environmental and occupational factors. We reviewed the first 1000 medical files of a multiethnic community, where all individuals shared similar living conditions. Only healthy adults age 15 to 60 years were included. Wave amplitudes were measured manually from the standard 12lead ECG. Minnesota coding was used. ECG from 597 subjects were included in the study: 350 Saudi Arabians, 95 Indians, 17 Sri-Lankans, 39 Filipinos, and 57 Caucasians; 349 were men. the mean +-SD of Sokolow-Lyon voltage (SLV) in men was signifcantly different among ethnic groups (2.9+-0.86, 2.64+-0.79, 2.73+-0.72, 3.23+-0.61, 2.94+-0.6, 2.58+-0.79 mV, P=0.0006, for Saudi's, Indians, Jordanians, Filipinos, Sri-Lankans, and Caucasians, respectively). SLV was similar among ethnic groups in women. The prevalence of early transition pattern was also different among ethnic groups in men but not women (15.8%, 34.6%, 17.9%, 21.7%, 35.3%, 26.8% in Suadi, Indian, Jordanian, Filipino, Sri-Lankan, and Caucasian, respectively, P=0.037). T wave amplitude was significantly different among ethnic groups in selected lead. ECG wave amplitude differs with ethnic region even when other factors are similar. Using SLV of 3.5 mV as a criterion may overestimate the incidence of left ventricular hypertrophy in some ethnic groups. The pattern of high R wave in lead V1is common in healthy adults in certain ethnic groups. T wave height differs with ethnic origin and sex. (author)

  19. Loop amplitudes in an extended gravity theory

    Science.gov (United States)

    Dunbar, David C.; Godwin, John H.; Jehu, Guy R.; Perkins, Warren B.

    2018-05-01

    We extend the S-matrix of gravity by the addition of the minimal three-point amplitude or equivalently adding R3 terms to the Lagrangian. We demonstrate how Unitarity can be used to simply examine the renormalisability of this theory and determine the R4 counter-terms that arise at one-loop. We find that the combination of R4 terms that arise in the extended theory is complementary to the R4 counter-term associated with supersymmetric Lagrangians.

  20. Loop-quantum-gravity vertex amplitude.

    Science.gov (United States)

    Engle, Jonathan; Pereira, Roberto; Rovelli, Carlo

    2007-10-19

    Spin foam models are hoped to provide the dynamics of loop-quantum gravity. However, the most popular of these, the Barrett-Crane model, does not have the good boundary state space and there are indications that it fails to yield good low-energy n-point functions. We present an alternative dynamics that can be derived as a quantization of a Regge discretization of Euclidean general relativity, where second class constraints are imposed weakly. Its state space matches the SO(3) loop gravity one and it yields an SO(4)-covariant vertex amplitude for Euclidean loop gravity.

  1. Speech production in amplitude-modulated noise

    DEFF Research Database (Denmark)

    Macdonald, Ewen N; Raufer, Stefan

    2013-01-01

    The Lombard effect refers to the phenomenon where talkers automatically increase their level of speech in a noisy environment. While many studies have characterized how the Lombard effect influences different measures of speech production (e.g., F0, spectral tilt, etc.), few have investigated...... the consequences of temporally fluctuating noise. In the present study, 20 talkers produced speech in a variety of noise conditions, including both steady-state and amplitude-modulated white noise. While listening to noise over headphones, talkers produced randomly generated five word sentences. Similar...... of noisy environments and will alter their speech accordingly....

  2. Optical twists in phase and amplitude

    DEFF Research Database (Denmark)

    Daria, Vincent R.; Palima, Darwin; Glückstad, Jesper

    2011-01-01

    where both phase and amplitude express a helical profile as the beam propagates in free space. Such a beam can be accurately referred to as an optical twister. We characterize optical twisters and demonstrate their capacity to induce spiral motion on particles trapped along the twisters’ path. Unlike LG...... beams, the far field projection of the twisted optical beam maintains a high photon concentration even at higher values of topological charge. Optical twisters have therefore profound applications to fundamental studies of light and atoms such as in quantum entanglement of the OAM, toroidal traps...

  3. First order correction to quasiclassical scattering amplitude

    International Nuclear Information System (INIS)

    Kuz'menko, A.V.

    1978-01-01

    First order (with respect to h) correction to quasiclassical with the aid of scattering amplitude in nonrelativistic quantum mechanics is considered. This correction is represented by two-loop diagrams and includes the double integrals. With the aid of classical equations of motion, the sum of the contributions of the two-loop diagrams is transformed into the expression which includes one-dimensional integrals only. The specific property of the expression obtained is that the integrand does not possess any singularities in the focal points of the classical trajectory. The general formula takes much simpler form in the case of one-dimensional systems

  4. Tomography for amplitudes of hard exclusive processes

    International Nuclear Information System (INIS)

    Polyakov, M.V.

    2008-01-01

    We discuss which part of information about hadron structure encoded in the Generalized Parton Distributions (GPDs) [part of total GPD image] can be restored from the known amplitude of a hard exclusive process. The physics content of this partial image is analyzed. Among other things, we show that this partial image contains direct information about how the target hadron responses to the (string) quark-antiquark operator of arbitrary spin J. Explicit equations relating physics content of the partial image of GPDs directly to the data are derived. Also some new results concerning the dual parametrization of GPDs are presented

  5. Inverse amplitude method and Adler zeros

    International Nuclear Information System (INIS)

    Gomez Nicola, A.; Pelaez, J. R.; Rios, G.

    2008-01-01

    The inverse amplitude method is a powerful unitarization technique to enlarge the energy applicability region of effective Lagrangians. It has been widely used to describe resonances in hadronic physics, combined with chiral perturbation theory, as well as in the strongly interacting symmetry breaking sector. In this work we show how it can be slightly modified to also account for the subthreshold region, incorporating correctly the Adler zeros required by chiral symmetry and eliminating spurious poles. These improvements produce negligible effects on the physical region.

  6. Survey of vibration amplitudes throughout the linac

    International Nuclear Information System (INIS)

    Werner, K.L.

    1984-01-01

    The magnitude of vibrations of the Linac structure due to on site disturbances, such as cooling towers, pumps, generators, Highway 280 overpass traffic, is of interest. CN-263, for example, discusses tolerances of random (i.e., uncorrelated) quad jitter and suggests that amplitudes should not exceed 0.7 microns rms. This note describes the results of a series of measurements carried out in the summer of 1983. In general, the tolerance is not exceeded, but there appears not to be a good safety factor at low frequencies

  7. Lipid metabolism during embryonic development of the common snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Lawniczak, Cynthia J; Teece, Mark A

    2009-05-01

    The metabolism of lipids and fatty acids during embryonic development of Chelydra serpentina (common snapping turtle) was investigated. Substantial changes in lipid class and fatty acid composition occurred as lipids were transferred from the yolk to the yolk sac membrane (YSM) and then to the brain, eyes, heart, and lungs of the hatchling. Lipids were hydrolyzed in the yolk prior to transport to the YSM, shown by a large increase in free fatty acids (FFAs) during the second half of development. Triglyceride-derived docosahexaenoic acid (DHA) was utilized preferentially to phospholipid-derived DHA. In the YSM, arachidonic acid (ARA) was selectively incorporated into phospholipids while DHA was preferentially incorporated into triglycerides. Selective incorporation of DHA and ARA into the brain and eyes, and ARA into the heart was observed, indicating the importance of these PUFAs for organ development and function. The amount of DHA and ARA in each organ was less than 1% of that measured in the yolk of the freshly laid egg, indicating that only a small portion of yolk PUFAs were incorporated into the hatchling organs studied. We discuss the differences in the mechanisms and utilization of yolk lipids in turtles compared with lipid uptake during embryonic development in birds.

  8. Toxicity of nitrogenous fertilizers to eggs of snapping turtles (Chelydra serpentina) in field and laboratory exposures.

    Science.gov (United States)

    de Solla, Shane Raymond; Martin, Pamela Anne

    2007-09-01

    Many reptiles oviposit in soil of agricultural landscapes. We evaluated the toxicity of two commonly used nitrogenous fertilizers, urea and ammonium nitrate, on the survivorship of exposed snapping turtle (Chelydra serpentina) eggs. Eggs were incubated in a community garden plot in which urea was applied to the soil at realistic rates of up to 200 kg/ha in 2004, and ammonium nitrate was applied at rates of up to 2,000 kg/ha in 2005. Otherwise, the eggs were unmanipulated and were subject to ambient temperature and weather conditions. Eggs were also exposed in the laboratory in covered bins so as to minimize loss of nitrogenous compounds through volatilization or leaching from the soil. Neither urea nor ammonium nitrate had any impact on hatching success or development when exposed in the garden plot, despite overt toxicity of ammonium nitrate to endogenous plants. Both laboratory exposures resulted in reduced hatching success, lower body mass at hatching, and reduced posthatching survival compared to controls. The lack of toxicity of these fertilizers in the field was probably due to leaching in the soil and through atmospheric loss. In general, we conclude that nitrogenous fertilizers probably have little direct impacts on turtle eggs deposited in agricultural landscapes.

  9. Toxicity of pesticides associated with potato production, including soil fumigants, to snapping turtle eggs (Chelydra serpentina).

    Science.gov (United States)

    de Solla, Shane Raymond; Palonen, Kimberley Elizabeth; Martin, Pamela Anne

    2014-01-01

    Turtles frequently oviposit in soils associated with agriculture and, thus, may be exposed to pesticides or fertilizers. The toxicity of a pesticide regime that is used for potato production in Ontario on the survivorship of snapping turtle (Chelydra serpentina) eggs was evaluated. The following treatments were applied to clean soil: 1) a mixture of the pesticides chlorothalonil, S-metolachlor, metribuzin, and chlorpyrifos, and 2) the soil fumigant metam sodium. Turtle eggs were incubated in soil in outdoor plots in which these mixtures were applied at typical and higher field application rates, where the eggs were subject to ambient temperature and weather conditions. The pesticide mixture consisting of chlorothalonil, S-metolachlor, metribuzin, and chlorpyrifos did not affect survivorship, deformities, or body size at applications up to 10 times the typical field application rates. Hatching success ranged between 87% and 100% for these treatments. Metam sodium was applied at 0.1¯ times, 0.3¯ times, 1 times, and 3 times field application rates. Eggs exposed to any application of metam sodium had 100% mortality. At typical field application rates, the chemical regime associated with potato production does not appear to have any detrimental impacts on turtle egg development, except for the use of the soil fumigant metam sodium, which is highly toxic to turtle eggs at the lowest recommended application rate. © 2013 SETAC.

  10. THE DEPENDENCE OF HEAT CONSUMPTION ON THE DYNAMICS OF EXTERNAL AIR TEMPERATURE DURING COLD SNAP PERIODS

    Directory of Open Access Journals (Sweden)

    Rymarov Andrey Georgievich

    2014-09-01

    Full Text Available The dynamics of outdoor temperature variations during the cold period of the year influences the operation of the systems providing the required microclimate in the premises, which may be subject to automation systems that affects the IQ of a building, it is important to note that in the last decade there has been a growth in the participation of intelligent technologies in the formation of a microclimate of buildings. Studying the microclimate quality in terms of energy consumption of the premises and the building considers climate variability and outdoor air pollution, which is connected with the economic aspects of energy efficiency and productivity, and health of workers, as a short-term temperature fall in the premises has harmful consequences. Low outdoor temperatures dry the air in the premises that requires accounting for climate control equipment and, if necessary, the personal account of its work. Excess heat in the premises, including office equipment, corrects the temperature conditions, which reduces the adverse effect of cold snap.

  11. Safety Test Program Summary SNAP 19 Pioneer Heat Source Safety Program

    Energy Technology Data Exchange (ETDEWEB)

    None,

    1971-07-01

    Sixteen heat source assemblies have been tested in support of the SNAP 19 Pioneer Safety Test Program. Seven were subjected to simulated reentry heating in various plasma arc facilities followed by impact on earth or granite. Six assemblies were tested under abort accident conditions of overpressure, shrapnel impact, and solid and liquid propellant fires. Three capsules were hot impacted under Transit capsule impact conditions to verify comparability of test results between the two similar capsule designs, thus utilizing both Pioneer and Transit Safety Test results to support the Safety Analysis Report for Pioneer. The tests have shown the fuel is contained under all nominal accident environments with the exception of minor capsule cracks under severe impact and solid fire environments. No catastrophic capsule failures occurred in this test which would release large quantities of fuel. In no test was fuel visible to the eye following impact or fire. Breached capsules were defined as those which exhibit thoria contamination on its surface following a test, or one which exhibited visible cracks in the post test metallographic analyses.

  12. Multichannel amplitude analyser for nuclear spectrometry

    International Nuclear Information System (INIS)

    Jankovic, S.; Milovanovic, B.

    2003-01-01

    A multichannel amplitude analyser with 4096 channels was designed. It is based on a fast 12-bit analog-to-digital converter. The intended purpose of the instrument is recording nuclear spectra by means of scintillation detectors. The computer link is established through an opto-isolated serial connection cable, thus reducing instrument sensitivity to disturbances originating from digital circuitry. Refreshing of the data displayed on the screen occurs on every 2.5 seconds. The impulse peak detection is implemented through the differentiation of the amplified input signal, while the synchronization with the data coming from the converter output is established by taking advantage of the internal 'pipeline' structure of the converter itself. The mode of operation of the built-in microcontroller provides that there are no missed impulses, and the simple logic network prevents the initiation of the amplitude reading sequence for the next impulse in case it appears shortly after its precedent. The solution proposed here demonstrated a good performance at a comparatively low manufacturing cost, and is thus suitable for educational purposes (author)

  13. Getting superstring amplitudes by degenerating Riemann surfaces

    International Nuclear Information System (INIS)

    Matone, Marco; Volpato, Roberto

    2010-01-01

    We explicitly show how the chiral superstring amplitudes can be obtained through factorisation of the higher genus chiral measure induced by suitable degenerations of Riemann surfaces. This powerful tool also allows to derive, at any genera, consistency relations involving the amplitudes and the measure. A key point concerns the choice of the local coordinate at the node on degenerate Riemann surfaces that greatly simplifies the computations. As a first application, starting from recent ansaetze for the chiral measure up to genus five, we compute the chiral two-point function for massless Neveu-Schwarz states at genus two, three and four. For genus higher than three, these computations include some new corrections to the conjectural formulae appeared so far in the literature. After GSO projection, the two-point function vanishes at genus two and three, as expected from space-time supersymmetry arguments, but not at genus four. This suggests that the ansatz for the superstring measure should be corrected for genus higher than four.

  14. The Construction of Spin Foam Vertex Amplitudes

    Directory of Open Access Journals (Sweden)

    Eugenio Bianchi

    2013-01-01

    Full Text Available Spin foam vertex amplitudes are the key ingredient of spin foam models for quantum gravity. These fall into the realm of discretized path integral, and can be seen as generalized lattice gauge theories. They can be seen as an attempt at a 4-dimensional generalization of the Ponzano-Regge model for 3d quantum gravity. We motivate and review the construction of the vertex amplitudes of recent spin foam models, giving two different and complementary perspectives of this construction. The first proceeds by extracting geometric configurations from a topological theory of the BF type, and can be seen to be in the tradition of the work of Barrett, Crane, Freidel and Krasnov. The second keeps closer contact to the structure of Loop Quantum Gravity and tries to identify an appropriate set of constraints to define a Lorentz-invariant interaction of its quanta of space. This approach is in the tradition of the work of Smolin, Markopoulous, Engle, Pereira, Rovelli and Livine.

  15. Fatigue life prediction of rotor blade composites: Validation of constant amplitude formulations with variable amplitude experiments

    International Nuclear Information System (INIS)

    Westphal, T; Nijssen, R P L

    2014-01-01

    The effect of Constant Life Diagram (CLD) formulation on the fatigue life prediction under variable amplitude (VA) loading was investigated based on variable amplitude tests using three different load spectra representative for wind turbine loading. Next to the Wisper and WisperX spectra, the recently developed NewWisper2 spectrum was used. Based on these variable amplitude fatigue results the prediction accuracy of 4 CLD formulations is investigated. In the study a piecewise linear CLD based on the S-N curves for 9 load ratios compares favourably in terms of prediction accuracy and conservativeness. For the specific laminate used in this study Boerstra's Multislope model provides a good alternative at reduced test effort

  16. Fatigue life prediction of rotor blade composites: Validation of constant amplitude formulations with variable amplitude experiments

    Science.gov (United States)

    Westphal, T.; Nijssen, R. P. L.

    2014-12-01

    The effect of Constant Life Diagram (CLD) formulation on the fatigue life prediction under variable amplitude (VA) loading was investigated based on variable amplitude tests using three different load spectra representative for wind turbine loading. Next to the Wisper and WisperX spectra, the recently developed NewWisper2 spectrum was used. Based on these variable amplitude fatigue results the prediction accuracy of 4 CLD formulations is investigated. In the study a piecewise linear CLD based on the S-N curves for 9 load ratios compares favourably in terms of prediction accuracy and conservativeness. For the specific laminate used in this study Boerstra's Multislope model provides a good alternative at reduced test effort.

  17. Amplitude mediated chimera states with active and inactive oscillators

    Science.gov (United States)

    Mukherjee, Rupak; Sen, Abhijit

    2018-05-01

    The emergence and nature of amplitude mediated chimera states, spatio-temporal patterns of co-existing coherent and incoherent regions, are investigated for a globally coupled system of active and inactive Ginzburg-Landau oscillators. The existence domain of such states is found to shrink and shift in parametric space with the increase in the fraction of inactive oscillators. The role of inactive oscillators is found to be twofold—they get activated to form a separate region of coherent oscillations and, in addition, decrease the common collective frequency of the coherent regions by their presence. The dynamical origin of these effects is delineated through a bifurcation analysis of a reduced model system that is based on a mean field approximation. Our results may have practical implications for the robustness of such states in biological or physical systems where age related deterioration in the functionality of components can occur.

  18. Does Fundus Fluorescein Angiography Procedure Affect Ocular Pulse Amplitude?

    Directory of Open Access Journals (Sweden)

    Gökhan Pekel

    2013-01-01

    Full Text Available Purpose. This study examines the effects of fundus fluorescein angiography (FFA procedure on ocular pulse amplitude (OPA and intraocular pressure (IOP. Materials and Methods. Sixty eyes of 30 nonproliferative diabetic retinopathy patients (15 males, 15 females were included in this cross-sectional case series. IOP and OPA were measured with the Pascal dynamic contour tonometer before and after 5 minutes of intravenous fluorescein dye injection. Results. Pre-FFA mean OPA value was  mmHg and post-FFA mean OPA value was  mmHg (. Pre-FFA mean IOP value was  mmHg and post-FFA mean IOP value was  mmHg (. Conclusion. Although both mean OPA and IOP values were decreased after FFA procedure, the difference was not statistically significant. This clinical trial is registered with Australian New Zealand Clinical Trials Registry number ACTRN12613000433707.

  19. Decreasing Relative Risk Premium

    DEFF Research Database (Denmark)

    Hansen, Frank

    relative risk premium in the small implies decreasing relative risk premium in the large, and decreasing relative risk premium everywhere implies risk aversion. We finally show that preferences with decreasing relative risk premium may be equivalently expressed in terms of certain preferences on risky......We consider the risk premium demanded by a decision maker with wealth x in order to be indifferent between obtaining a new level of wealth y1 with certainty, or to participate in a lottery which either results in unchanged present wealth or a level of wealth y2 > y1. We define the relative risk...... premium as the quotient between the risk premium and the increase in wealth y1–x which the decision maker puts on the line by choosing the lottery in place of receiving y1 with certainty. We study preferences such that the relative risk premium is a decreasing function of present wealth, and we determine...

  20. Thrombelastography Early Amplitudes in bleeding and coagulopathic trauma patients

    DEFF Research Database (Denmark)

    Laursen, Thomas Holst; Meyer, Martin A S; Meyer, Anna Sina P

    2018-01-01

    BACKGROUND: Early amplitudes in the viscoelastic hemostatic assays Thrombelastography (TEG) and Rotation Thromboelastometry (ROTEM) provide fast results, which is critical in resuscitation of bleeding patients. This study investigated associations between TEG early amplitudes and standard TEG var...

  1. Decreasing Serial Cost Sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter

    The increasing serial cost sharing rule of Moulin and Shenker [Econometrica 60 (1992) 1009] and the decreasing serial rule of de Frutos [Journal of Economic Theory 79 (1998) 245] have attracted attention due to their intuitive appeal and striking incentive properties. An axiomatic characterization...... of the increasing serial rule was provided by Moulin and Shenker [Journal of Economic Theory 64 (1994) 178]. This paper gives an axiomatic characterization of the decreasing serial rule...

  2. Decreasing serial cost sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter Raahave

    2009-01-01

    The increasing serial cost sharing rule of Moulin and Shenker (Econometrica 60:1009-1037, 1992) and the decreasing serial rule of de Frutos (J Econ Theory 79:245-275, 1998) are known by their intuitive appeal and striking incentive properties. An axiomatic characterization of the increasing serial...... rule was provided by Moulin and Shenker (J Econ Theory 64:178-201, 1994). This paper gives an axiomatic characterization of the decreasing serial rule....

  3. Variational principles for the projected breakup amplitude

    International Nuclear Information System (INIS)

    Hahn, Y.

    1976-01-01

    Two alternate forms of variational principles for the breakup amplitude describing the two- to three-cluster transition are derived such that all the integrals involved in the intermediate stages are well defined. The first form contains a trial Green's function with which both the initial and final state trial wave functions are constructed. The earlier form of the Kohn-type variational principle derived by Lieber, Rosenberg, and Spruch is recovered, however, when this connection between the trial functions is removed. The second form of the variational principle is derived by projecting out from the trial functions all the open channel components which correspond to the two-cluster structures including the rearrangement channels. The remaining part of the wave functions describes the channels with three-cluster structures, and the integrals involving this part are then mathematically well defined

  4. Single isospin decay amplitude and CP violation

    Energy Technology Data Exchange (ETDEWEB)

    Deshpande, N.G. [Oregon Univ., Eugene, OR (United States). Inst. of Theoretical Science; He, Xiaogang [Melbourne Univ., Parkville, VIC (Australia). School of Physics; Pakvasa, S. [Hawaii Univ., Honolulu, HI (United States). Dept. of Physics and Astronomy

    1996-06-01

    While for K meson or hyperon decays, the partial rate asymmetries are always zero if the final states are single isospin states, in B decays the situation is dramatically different and partial rate asymmetries can be non-zero if the final states are single isospin states. Partial rate asymmetries were calculated for several B decays with single isospin amplitude in the finale states using factorization approximation. It was found that more intermediate on-shell states with different Cabbibbo-Kobayashi-Maskawa factors are allowed in B decay and CP violating partial rate asymmetries need not to be zero even if the final state contains only a single isospin state. 17 refs., 4 figs.

  5. Large amplitude parallel propagating electromagnetic oscillitons

    International Nuclear Information System (INIS)

    Cattaert, Tom; Verheest, Frank

    2005-01-01

    Earlier systematic nonlinear treatments of parallel propagating electromagnetic waves have been given within a fluid dynamic approach, in a frame where the nonlinear structures are stationary and various constraining first integrals can be obtained. This has lead to the concept of oscillitons that has found application in various space plasmas. The present paper differs in three main aspects from the previous studies: first, the invariants are derived in the plasma frame, as customary in the Sagdeev method, thus retaining in Maxwell's equations all possible effects. Second, a single differential equation is obtained for the parallel fluid velocity, in a form reminiscent of the Sagdeev integrals, hence allowing a fully nonlinear discussion of the oscilliton properties, at such amplitudes as the underlying Mach number restrictions allow. Third, the transition to weakly nonlinear whistler oscillitons is done in an analytical rather than a numerical fashion

  6. Amplitude and phase modulation with waveguide optics

    International Nuclear Information System (INIS)

    Burkhart, S.C.; Wilcox, R.B.; Browning, D.; Penko, F.A.

    1996-01-01

    We have developed amplitude and phase modulation systems for glass lasers using integrated electro-optic modulators and solid state high-speed electronics. The present and future generation of lasers for Inertial Confinement Fusion require laser beams with complex temporal and phase shaping to compensate for laser gain saturation, mitigate parametric processes such as transverse stimulated Brillouin scattering in optics, and to provide specialized drive to the fusion targets. These functions can be performed using bulk optoelectronic modulators, however using high-speed electronics to drive low voltage integrated optical modulators has many practical advantages. In particular, we utilize microwave GaAs transistors to perform precision, 250 ps resolution temporal shaping. Optical bandwidth is generated using a microwave oscillator at 3 GHz amplified by a solid state amplifier. This drives an integrated electrooptic modulator to achieve laser bandwidths exceeding 30 GHz

  7. Topological amplitudes in heterotic superstring theory

    International Nuclear Information System (INIS)

    Antoniadis, I.; Taylor, T.R.

    1996-06-01

    We show that certain heterotic string amplitudes are given in terms of correlators of the twisted topological (2,0) SCFT, corresponding to the internal sector of the N = 1 spacetime supersymmetric background. The genus g topological partition function F g corresponds to a term in the effective action of the form W 2g , where W is the gauge or gravitational superfield. We study also recursion relations related to holomorphic anomalies, showing that, contrary to the type II case, they involve correlators of anti-chiral superfields. The corresponding terms in the effective action are of the form W 2g II n , where II is a chiral superfield obtained by chiral projection of a general superfield. We observe that the structure of the recursion relations is that of N = 1 spacetime supersymmetry Ward identity. We give also a solution of the tree level recursion relations and discuss orbifold examples. (author). 23 refs, 2 figs

  8. Polynomial structures in one-loop amplitudes

    International Nuclear Information System (INIS)

    Britto, Ruth; Feng Bo; Yang Gang

    2008-01-01

    A general one-loop scattering amplitude may be expanded in terms of master integrals. The coefficients of the master integrals can be obtained from tree-level input in a two-step process. First, use known formulas to write the coefficients of (4-2ε)-dimensional master integrals; these formulas depend on an additional variable, u, which encodes the dimensional shift. Second, convert the u-dependent coefficients of (4-2ε)-dimensional master integrals to explicit coefficients of dimensionally shifted master integrals. This procedure requires the initial formulas for coefficients to have polynomial dependence on u. Here, we give a proof of this property in the case of massless propagators. The proof is constructive. Thus, as a byproduct, we produce different algebraic expressions for the scalar integral coefficients, in which the polynomial property is apparent. In these formulas, the box and pentagon contributions are separated explicitly.

  9. Amplitude correlations for inelastic proton scattering from 48Ti

    International Nuclear Information System (INIS)

    Chou, B.H.; Mitchell, G.E.; Bilpuch, E.G.; Westerfeldt, C.R.

    1981-01-01

    The magnitudes and relative signs of inelastic proton channel amplitudes were determined for three decay channels for 45 5/2 + resonances in 49 V. The reduced widths in each channel follow a Porter-Thomas distribution, but extremely large amplitude correlations are observed - for one pair of channel amplitudes the relative sign is positive for 43 of 45 resonances. These results provide the first direct test of the Krieger-Porter reduced width amplitude distribution. (orig.)

  10. Tree-level gluon amplitudes on the celestial sphere

    Science.gov (United States)

    Schreiber, Anders Ø.; Volovich, Anastasia; Zlotnikov, Michael

    2018-06-01

    Pasterski, Shao and Strominger have recently proposed that massless scattering amplitudes can be mapped to correlators on the celestial sphere at infinity via a Mellin transform. We apply this prescription to arbitrary n-point tree-level gluon amplitudes. The Mellin transforms of MHV amplitudes are given by generalized hypergeometric functions on the Grassmannian Gr (4 , n), while generic non-MHV amplitudes are given by more complicated Gelfand A-hypergeometric functions.

  11. Correlations for reduced-width amplitudes in 49V

    International Nuclear Information System (INIS)

    Chou, B.H.; Mitchell, G.E.; Bilpuch, E.G.; Westerfeldt, C.R.

    1980-01-01

    Measurement of the relative sign of inelastic proton-channel amplitudes permits the determination of amplitude correlations. Data were obtained for 45 5/2 + resonances in 49 V. Although the reduced widths in each channel followed a Porter-Thomas distribution, large amplitude correlations were observed. The results are compared with the reduced-width--amplitude distribution of Krieger and Porter. This is the first direct test of the Krieger-Porter distribution

  12. Ozone tolerance in snap bean is associated with elevated ascorbic acid in the leaf apoplast

    Energy Technology Data Exchange (ETDEWEB)

    Burkey, K.O. [North Carolina State Univ., United States Dept. of Agriculture-Agricultural Research Service, and Dept. of Crop Science, Raleigh, NC (United States); Eason, G. [North Carolina, State Univ., United States Dept. of Plant Pathology, Raleigh, NC (United States)

    2002-03-01

    Ascorbic acid (AA) in the leaf apoplast has the potential to limit ozone injury by participating in reactions that detoxify ozone and reactive oxygen intermediates and thus prevent plasma membrane damage. Genotypes of snap bean (Phaseolus vulgaris L) were compared in controlled environments and in open-top field chambers to assess the relationship between extracellular AA content and ozone tolerance. Vacuum infiltration methods were employed to separate leaf AA into extracellular and intracellular fractions. For plants grown in controlled environments at low ozone concentration (4 nmol mol{sup -1} ozone), leaf apoplast AA was significantly higher in tolerant genotypes (300-400 nmol g{sup -1} FW) compared with sensitive genotypes (approximately 50 nmol g{sup -1} FW), evidence that ozone tolerance is associated with elevated extracellular AA. For the open top chamber study, plants were grown in pots under charcoal-filtered air (CF) conditions and then either maintained under CF conditions (29 nmol mol{sup -1} ozone) or exposed to elevated ozone (67 nmol mol{sup -1} ozone). Following an 8-day treatment period, leaf apoplast AA was in the range of 100-190 nmol g{sup -1} FW for all genotypes, but no relationship was observed between apoplast AA content and ozone tolerance. The contrasting results in the two studies demonstrated a potential limitation in the interpretation of extracellular AA data. Apoplast AA levels presumably reflect the steady-state condition between supply from the cytoplasm and utilization within the cell wall. The capacity to detoxify ozone in the extracellular space may be underestimated under elevated ozone conditions where the dynamics of AA supply and utilization are not adequately represented by a steady-state measurement. (au)

  13. A Novel Candidate Gene for Temperature-Dependent Sex Determination in the Common Snapping Turtle

    Science.gov (United States)

    Schroeder, Anthony L.; Metzger, Kelsey J.; Miller, Alexandra; Rhen, Turk

    2016-01-01

    Temperature-dependent sex determination (TSD) was described nearly 50 years ago. Researchers have since identified many genes that display differential expression at male- vs. female-producing temperatures. Yet, it is unclear whether these genes (1) are involved in sex determination per se, (2) are downstream effectors involved in differentiation of ovaries and testes, or (3) are thermo-sensitive but unrelated to gonad development. Here we present multiple lines of evidence linking CIRBP to sex determination in the snapping turtle, Chelydra serpentina. We demonstrate significant associations between a single nucleotide polymorphism (SNP) (c63A > C) in CIRBP, transcript levels in embryonic gonads during specification of gonad fate, and sex in hatchlings from a thermal regime that produces mixed sex ratios. The A allele was induced in embryos exposed to a female-producing temperature, while expression of the C allele did not differ between female- and male-producing temperatures. In accord with this pattern of temperature-dependent, allele-specific expression, AA homozygotes were more likely to develop ovaries than AC heterozygotes, which, in turn, were more likely to develop ovaries than CC homozygotes. Multiple regression using SNPs in CIRBP and adjacent loci suggests that c63A > C may be the causal variant or closely linked to it. Differences in CIRBP allele frequencies among turtles from northern Minnesota, southern Minnesota, and Texas reflect small and large-scale latitudinal differences in TSD pattern. Finally, analysis of CIRBP protein localization reveals that CIRBP is in a position to mediate temperature effects on the developing gonads. Together, these studies strongly suggest that CIRBP is involved in determining the fate of the bipotential gonad. PMID:26936926

  14. Heritable Variation for Sex Ratio under Environmental Sex Determination in the Common Snapping Turtle (Chelydra Serpentina)

    Science.gov (United States)

    Janzen, F. J.

    1992-01-01

    The magnitude of quantitative genetic variation for primary sex ratio was measured in families extracted from a natural population of the common snapping turtle (Chelydra serpentina), which possesses temperature-dependent sex determination (TSD). Eggs were incubated at three temperatures that produced mixed sex ratios. This experimental design provided estimates of the heritability of sex ratio in multiple environments and a test of the hypothesis that genotype X environment (G X E) interactions may be maintaining genetic variation for sex ratio in this population of C. serpentina. Substantial quantitative genetic variation for primary sex ratio was detected in all experimental treatments. These results in conjunction with the occurrence of TSD in this species provide support for three critical assumptions of Fisher's theory for the microevolution of sex ratio. There were statistically significant effects of family and incubation temperature on sex ratio, but no significant interaction was observed. Estimates of the genetic correlations of sex ratio across environments were highly positive and essentially indistinguishable from +1. These latter two findings suggest that G X E interaction is not the mechanism maintaining genetic variation for sex ratio in this system. Finally, although substantial heritable variation exists for primary sex ratio of C. serpentina under constant temperatures, estimates of the effective heritability of primary sex ratio in nature are approximately an order of magnitude smaller. Small effective heritability and a long generation time in C. serpentina imply that evolution of sex ratios would be slow even in response to strong selection by, among other potential agents, any rapid and/or substantial shifts in local temperatures, including those produced by changes in the global climate. PMID:1592234

  15. Corrections to the box diagram amplitude due to kaon mass

    International Nuclear Information System (INIS)

    Datta, A.; Kumbhakar, D.

    1985-08-01

    The K 0 -anti-K 0 mixing amplitude is calculated without using the standard zero external momentum approximation. The resulting corrections are numerically significant for the real part of the amplitude. In the imaginary part of the amplitude the effects of similar corrections are less important. Implications for Δmsub(k) and epsilon are discussed. (author)

  16. MHV Vertices And Tree Amplitudes In Gauge Theory

    International Nuclear Information System (INIS)

    Cachazo, Freddy; Svrcek, Peter; Witten, Edward

    2004-01-01

    As an alternative to the usual Feynman graphs, tree amplitudes in Yang-Mills theory can be constructed from tree graphs in which the vertices are tree level MHV scattering amplitudes, continued off shell in a particular fashion. The formalism leads to new and relatively simple formulas for many amplitudes, and can be heuristically derived from twistor space. (author)

  17. An improved method to prepare an injectable microemulsion of the galanin-receptor 3 selective antagonist, SNAP 37889, using Kolliphor® HS 15

    Science.gov (United States)

    Scheller, Karlene J.; Williams, Spencer J.; Lawrence, Andrew J.; Jarrott, Bevyn; Djouma, Elvan

    2014-01-01

    Research into the galanin-3 (GAL3) receptor has many challenges, including the lack of commercially available selective ligands. While the identification of non-peptidergic GAL3 receptor-selective antagonists, 1-phenyl-3-[3-(trifluoromethyl)phenyl]iminoindol-2-one (SNAP 37889) and 1-[3-(2-pyrrolidin-1-ylethoxy)phenyl]-3-[3-(trifluoromethyl)phenyl]iminoindol-2-one (SNAP 398299) have implicated a role for GAL3 receptors in anxiety, depression and drug-seeking behaviour, a major limitation of their use is poor aqueous solubility. Previously we have used 5% dimethylsulfoxide (DMSO) with 1% hydroxypropylmethyl cellulose in saline to dissolve SNAP 37889 for intraperitoneal (i.p.) injections of rats; however this produced a micro-suspension that was not ideal. The injectable formulation of SNAP 37889 was improved as follows:•30% (w/v) Kolliphor® HS 15 (Solutol HS® 15) and sodium phosphate buffer (0.01 M, pH 7.4) were used as vehicles.•A smooth glass mortar and pestle was used to triturate the Kolliphor® HS 15 and SNAP 37889 into a paste before addition to the sodium phosphate buffer at room temperature (RT).•The resulting mixture was vortexed until the paste was fully dissolved and the microemulsion was allowed to sit for 20 min to allow air bubbles to coalesce. PMID:26150955

  18. Non-supersymmetric loop amplitudes and MHV vertices

    International Nuclear Information System (INIS)

    Bedford, James; Brandhuber, Andreas; Spence, Bill; Travaglini, Gabriele

    2005-01-01

    We show how the MHV diagram description of Yang-Mills theories can be used to study non-supersymmetric loop amplitudes. In particular, we derive a compact expression for the cut-constructible part of the general one-loop MHV multi-gluon scattering amplitude in pure Yang-Mills theory. We show that in special cases this expression reduces to known amplitudes-the amplitude with adjacent negative-helicity gluons, and the five gluon non-adjacent amplitude. Finally, we briefly discuss the twistor space interpretation of our result

  19. Phase and amplitude detection system for the Stanford Linear Accelerator

    International Nuclear Information System (INIS)

    Fox, J.D.; Schwarz, H.D.

    1983-01-01

    A computer controlled phase and amplitude detection system to measure and stabilize the rf power sources in the Stanford Linear Accelerator is described. This system measures the instantaneous phase and amplitude of a 1 microsecond 2856 MHz rf pulse and will be used for phase feedback control and for amplitude and phase jitter detection. This paper discusses the measurement system performance requirements for the operation of the Stanford Linear Collider, and the design and implementation of the phase and amplitude detection system. The fundamental software algorithms used in the measurement are described, as is the performance of the prototype phase and amplitude detector system

  20. Extra-articular subcutaneous "inverted king post-truss" ligament reconstruction for severe swan neck deformity (snapping finger).

    Science.gov (United States)

    de Soras, X; de Mourgues, P; Pradel, P; Urien, J-P; Beaudoin, E

    2017-02-01

    A swan neck deformity (SND) can be well tolerated for a long time, until the appearance of a disabling "snapping finger". In its most advanced condition, the other hand is needed to initiate finger flexion. We propose a technique of extra-articular, subcutaneous ligament reconstruction with an "inverted king post-truss" configuration use in roofs and to reinforce railway bridges. An artificial ligament (MaxBraid™ polyethylene surgical suture, 5 metric, Biomet) makes a figure of eight between transosseous tunnels in the proximal and middle phalanges, crossing over top of the A3 pulley. We limited our series to severe SND cases with "snapping finger". We excluded isolated SNDs without functional disability. Eleven patients were followed for 3.4 years on average. The cause was an acute injury 8 times (7 balloon accidents), rheumatoid arthritis 2 times and overuse once (saxophone). Only one case was a poor outcome of mallet finger. The 11 patients were reassessed by a telephone survey. Two patients underwent reoperation: one for a ligament rupture, the other one for a knot that became untied. One patient had a suspected late rupture but without recurrence of the disabling snapping finger. The 11 patients considered themselves improved by the intervention. Nine patients did not notice any difference between their operated finger and the contralateral side. Return to manual activity was possible once the skin had healed. The technique is simpler than the spiral oblique retinacular ligament (SORL) reconstruction technique described by Thomson-Littler and also less demanding because it does not involve the distal interphalangeal joint. It requires only a short incision in the volar crease of the proximal interphalangeal joint. No tendon or ligament is sacrificed. Neither postoperative immobilization nor lengthy physical therapy is needed. Complications can be avoided by selecting the appropriate artificial ligament material and careful knot tying. Copyright © 2016 SFCM

  1. Decreasing relative risk premium

    DEFF Research Database (Denmark)

    Hansen, Frank

    2007-01-01

    such that the corresponding relative risk premium is a decreasing function of present wealth, and we determine the set of associated utility functions. We find a new characterization of risk vulnerability and determine a large set of utility functions, closed under summation and composition, which are both risk vulnerable...

  2. Decreasing asthma morbidity

    African Journals Online (AJOL)

    1994-12-12

    Dec 12, 1994 ... Apart from the optimal use of drugs, various supplementary methods have been tested to decrease asthma morbidity, usually in patients from reiatively affluent socio-economic backgrounds. A study of additional measures taken in a group of moderate to severe adult asthmatics from very poor socio- ...

  3. Leading Wave Amplitude of a Tsunami

    Science.gov (United States)

    Kanoglu, U.

    2015-12-01

    Okal and Synolakis (EGU General Assembly 2015, Geophysical Research Abstracts-Vol. 17-7622) recently discussed that why the maximum amplitude of a tsunami might not occur for the first wave. Okal and Synolakis list observations from 2011 Japan tsunami, which reached to Papeete, Tahiti with a fourth wave being largest and 72 min later after the first wave; 1960 Chilean tsunami reached Hilo, Hawaii with a maximum wave arriving 1 hour later with a height of 5m, first wave being only 1.2m. Largest later waves is a problem not only for local authorities both in terms of warning to the public and rescue efforts but also mislead the public thinking that it is safe to return shoreline or evacuated site after arrival of the first wave. Okal and Synolakis considered Hammack's (1972, Ph.D. Dissertation, Calif. Inst. Tech., 261 pp., Pasadena) linear dispersive analytical solution with a tsunami generation through an uplifting of a circular plug on the ocean floor. They performed parametric study for the radius of the plug and the depth of the ocean since these are the independent scaling lengths in the problem. They identified transition distance, as the second wave being larger, regarding the parameters of the problem. Here, we extend their analysis to an initial wave field with a finite crest length and, in addition, to a most common tsunami initial wave form of N-wave as presented by Tadepalli and Synolakis (1994, Proc. R. Soc. A: Math. Phys. Eng. Sci., 445, 99-112). We compare our results with non-dispersive linear shallow water wave results as presented by Kanoglu et al. (2013, Proc. R. Soc. A: Math. Phys. Eng. Sci., 469, 20130015), investigating focusing feature. We discuss the results both in terms of leading wave amplitude and tsunami focusing. Acknowledgment: The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 603839 (Project ASTARTE - Assessment, Strategy and Risk

  4. Effects of amplitude modulation on perception of wind turbine noise

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Ki Seop; Lee, Soo Gab; Gwak, Doo Young [Dept. of Mechanical and Aerospace Engineering, Seoul National University, Seoul (Korea, Republic of); Seong, Yeol Wan [Ammunition Engineering Team, Defense Agency for Technology and Quality, Daejeon (Korea, Republic of); Lee, Seung Hoon [Aerodynamics Research Team, Korea Aerospace Research Institute, Daejeon (Korea, Republic of); Hong, Ji Young [Transportation Environmental Research Team, Green Transport and Logistics Institute, Korea Railroad Research Institute, Uiwang (Korea, Republic of)

    2016-10-15

    Wind turbine noise is considered to be easily detectable and highly annoying at relatively lower sound levels than other noise sources. Many previous studies attributed this characteristic to amplitude modulation. However, it is unclear whether amplitude modulation is the main cause of these properties of wind turbine noise. Therefore, the aim of the current study is to identify the relationship between amplitude modulation and these two properties of wind turbine noise. For this investigation, two experiments were conducted. In the first experiment, 12 participants determined the detection thresholds of six target sounds in the presence of background noise. In the second experiment, 12 participants matched the loudness of modified sounds without amplitude modulation to that of target sounds with amplitude modulation. The results showed that the detection threshold was lowered as the modulation depth increased; additionally, sounds with amplitude modulation had higher subjective loudness than those without amplitude modulation.

  5. Effects of amplitude modulation on perception of wind turbine noise

    International Nuclear Information System (INIS)

    Yoon, Ki Seop; Lee, Soo Gab; Gwak, Doo Young; Seong, Yeol Wan; Lee, Seung Hoon; Hong, Ji Young

    2016-01-01

    Wind turbine noise is considered to be easily detectable and highly annoying at relatively lower sound levels than other noise sources. Many previous studies attributed this characteristic to amplitude modulation. However, it is unclear whether amplitude modulation is the main cause of these properties of wind turbine noise. Therefore, the aim of the current study is to identify the relationship between amplitude modulation and these two properties of wind turbine noise. For this investigation, two experiments were conducted. In the first experiment, 12 participants determined the detection thresholds of six target sounds in the presence of background noise. In the second experiment, 12 participants matched the loudness of modified sounds without amplitude modulation to that of target sounds with amplitude modulation. The results showed that the detection threshold was lowered as the modulation depth increased; additionally, sounds with amplitude modulation had higher subjective loudness than those without amplitude modulation

  6. The Snapping Elbow Syndrome as a Reason for Chronic Elbow Neuralgia in a Tennis Player - MR, US and Sonoelastography Evaluation.

    Science.gov (United States)

    Łasecki, Mateusz; Olchowy, Cyprian; Pawluś, Aleksander; Zaleska-Dorobisz, Urszula

    2014-01-01

    Ulnar neuropathy is the second most common peripheral nerve neuropathy after median neuropathy, with an incidence of 25 cases per 100 000 men and 19 cases per 100 000 women each year. Skipping (snapping) elbow syndrome is an uncommon cause of pain in the posterior-medial elbow area, sometimes complicated by injury of the ulnar nerve. One of the reason is the dislocation of the abnormal insertion of the medial triceps head over the medial epicondyle during flexion and extension movements. Others are: lack of the Osboune fascia leading to ulnar nerve instability and focal soft tissue tumors (fibromas, lipomas, etc). Recurrent subluxation of the nerve at the elbow results in a tractional and frictional neuritis with classical symptoms of peripheral neuralgia. As far as we know snapping triceps syndrome had never been evaluated in sonoelastography. A 28yo semi-professional left handed tennis player was complaining about pain in posterior-medial elbow area. Initial US examination suggest golfers elbow syndrome which occurs quite commonly and has a prevalence of 0.3-0.6% in males and 0-3-1.1% in women and may be associated (approx. 50% of cases) with ulnar neuropathy. However subsequently made MRI revealed unusual distal triceps anatomy, moderate ulnar nerve swelling and lack of medial epicondylitis symptoms. Followed (second) US examination and sonoelastography have detected slipping of the both ulnar nerve and the additional band of the medial triceps head. Snapping elbow syndrome is a poorly known medical condition, sometimes misdiagnosed as the medial epicondylitis. It describes a broad range of pathologies and anatomical abnormalities. One of the most often reasons is the slipping of the ulnar nerve as the result of the Osborne fascia/anconeus epitrochlearis muscle absence. Simultaneously presence of two or more "snapping reasons" is rare but should be always taken under consideration. There are no sonoelastography studies describing golfers elbow syndrome

  7. Proteome stability analysis of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human colon mucosal biopsies

    DEFF Research Database (Denmark)

    Bjerg Bennike, Tue; Kastaniegaard, Kenneth; Padurariu, Simona

    2016-01-01

    Large repositories of well characterized RNAlater preserved samples and formalin-fixed, paraffin-embedded samples have been generated worldwide. However, the impact on the proteome of the preservation methods remain poorly described. Therefore, we analyzed the impact on the proteome of preserving...... samples in RNAlater, and by formalin-fixation, paraffin-embedding on human soft tissue, using directly frozen samples as a control ("Comparing the proteome of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human tissue samples" [1]). We here report the data from the analysis...

  8. The pulsed amplitude unit for the SLC

    International Nuclear Information System (INIS)

    Rolfe, J.; Browne, M.J.; Jobe, R.K.

    1987-02-01

    There is a recurring requirement in the SLC for the control of devices such as magnets, phase shifters, and attenuators on a beam-by-beam basis. The Pulsed Amplitude Unit (PAU) is a single width CAMAC module developed for this purpose. It provides digitally programmed analog output voltages on a beam-by-beam basis. Up to 32 preprogrammed values of output voltage are available from the single analog output of the module, and any of these values can be associated with any of the 256 possible SLC beam definitions. A 12-bit Analog-to-Digital Converter (ADC) digitizes an analog input signal at the appropriate beam time and stores it in a buffer memory. This feature is normally used to monitor the response of the device being controlled by the PAU at each beam time. Initial application of the PAU is a part of the system that controls the output of Klystrons in the SLC. The PAU combines several different functions in a single module. In order to accommodate these functions in a single width CAMAC module, field programmed logic is used extensively. Field Programmable Logic Arrays, Programmed Array Logic, and a Field Programmable Logic Sequencer are employed

  9. Gearbox Vibration Signal Amplitude and Frequency Modulation

    Directory of Open Access Journals (Sweden)

    Fakher Chaari

    2012-01-01

    Full Text Available Gearboxes usually run under fluctuating load conditions during service, however most of papers available in the literature describe models of gearboxes under stationary load conditions. Main task of published papers is fault modeling for their detection. Considering real situation from industry, the assumption of stationarity of load conditions cannot be longer kept. Vibration signals issued from monitoring in maintenance operations differ from mentioned models (due to load non-stationarity and may be difficult to analyze which lead to erroneous diagnosis of the system. The objective of this paper is to study the influence of time varying load conditions on a gearbox dynamic behavior. To investigate this, a simple spur gear system without defects is modeled. It is subjected to a time varying load. The speed-torque characteristic of the driving motor is considered. The load variation induces speed variation, which causes a variation in the gearmesh stiffness period. Computer simulation shows deep amplitude modulations with sidebands that don't differ from those obtained when there is a defective tooth. In order to put in evidence the time varying load effects, Short Time Fourier Transform and then Smoothed Wigner-Ville distribution are used. Results show that the last one is well suited for the studied case.

  10. Electroweak amplitudes in chiral quark models

    International Nuclear Information System (INIS)

    Fiolhais, Manuel

    2004-01-01

    After referring to some basic features of chiral models for baryons, with quarks and mesons, we describe how to construct model states representing physical baryons. We consider soliton models such as the Linear Sigma Model or the Chromodielectric Model, and bag models such as the Cloudy Bag Model. These models are solved approximately using variational approaches whose starting point is a mean-field description. We go beyond the mean-field description by introducing quantum fluctuations in the mesonic degrees of freedom. This is achieved, in a first step, by using a quantum state to represent meson clouds and, secondly, by performing an angular momentum and isospin projection from the mean-field state (actually a coherent state). Model states for baryons (nucleon, Delta, Roper) constructed in this way are used to determine several physical properties. I this seminar we paid a particular attention to the nucleon-delta electromagnetic and weak transition, presenting the model predictions for the electromagnetic and axial amplitudes

  11. Nonlinear amplitude dynamics in flagellar beating.

    Science.gov (United States)

    Oriola, David; Gadêlha, Hermes; Casademunt, Jaume

    2017-03-01

    The physical basis of flagellar and ciliary beating is a major problem in biology which is still far from completely understood. The fundamental cytoskeleton structure of cilia and flagella is the axoneme, a cylindrical array of microtubule doublets connected by passive cross-linkers and dynein motor proteins. The complex interplay of these elements leads to the generation of self-organized bending waves. Although many mathematical models have been proposed to understand this process, few attempts have been made to assess the role of dyneins on the nonlinear nature of the axoneme. Here, we investigate the nonlinear dynamics of flagella by considering an axonemal sliding control mechanism for dynein activity. This approach unveils the nonlinear selection of the oscillation amplitudes, which are typically either missed or prescribed in mathematical models. The explicit set of nonlinear equations are derived and solved numerically. Our analysis reveals the spatio-temporal dynamics of dynein populations and flagellum shape for different regimes of motor activity, medium viscosity and flagellum elasticity. Unstable modes saturate via the coupling of dynein kinetics and flagellum shape without the need of invoking a nonlinear axonemal response. Hence, our work reveals a novel mechanism for the saturation of unstable modes in axonemal beating.

  12. An amplitude modulated radio frequency plasma generator

    Science.gov (United States)

    Lei, Fan; Li, Xiaoping; Liu, Yanming; Liu, Donglin; Yang, Min; Xie, Kai; Yao, Bo

    2017-04-01

    A glow discharge plasma generator and diagnostic system has been developed to study the effects of rapidly variable plasmas on electromagnetic wave propagation, mimicking the plasma sheath conditions encountered in space vehicle reentry. The plasma chamber is 400 mm in diameter and 240 mm in length, with a 300-mm-diameter unobstructed clear aperture. Electron densities produced are in the mid 1010 electrons/cm3. An 800 W radio frequency (RF) generator is capacitively coupled through an RF matcher to an internally cooled stainless steel electrode to form the plasma. The RF power is amplitude modulated by a waveform generator that operates at different frequencies. The resulting plasma contains electron density modulations caused by the varying power levels. A 10 GHz microwave horn antenna pair situated on opposite sides of the chamber serves as the source and detector of probe radiation. The microwave power feed to the source horn is split and one portion is sent directly to a high-speed recording oscilloscope. On mixing this with the signal from the pickup horn antenna, the plasma-induced phase shift between the two signals gives the path-integrated electron density with its complete time dependent variation. Care is taken to avoid microwave reflections and extensive shielding is in place to minimize electronic pickup. Data clearly show the low frequency modulation of the electron density as well as higher harmonics and plasma fluctuations.

  13. Open string topological amplitudes and gaugino masses

    International Nuclear Information System (INIS)

    Antoniadis, I.; Narain, K.S.; Taylor, T.R.

    2005-09-01

    We discuss the moduli-dependent couplings of the higher derivative F-terms (TrW 2 ) h-1 , where W is the gauge N =1 chiral superfield. They are determined by the genus zero topological partition function F (0,h) , on a world-sheet with h boundaries. By string duality, these terms are also related to heterotic topological amplitudes studied in the past, with the topological twist applied only in the left-moving supersymmetric sector of the internal N =(2,0) superconformal field theory. The holomorphic anomaly of these couplings relates them to terms of the form Π n (TrW 2 ) h-2 , where Π's represent chiral projections of non-holomorphic functions of chiral superfields. An important property of these couplings is that they violate R-symmetry for h ≥ 3. As a result, once supersymmetry is broken by D-term expectation values, (TrW 2 ) 2 generates gaugino masses that can be hierarchically smaller than the scalar masses, behaving as m 1/2 ∼ m 0 4 in string units. Similarly, ΠTrW 2 generates Dirac masses for non-chiral brane fermions, of the same order of magnitude. This mechanism can be used for instance to obtain fermion masses at the TeV scale for scalar masses as high as m 0 ∼ O (10 13 ) GeV. We present explicit examples in toroidal string compactifications with intersecting D-branes. (author)

  14. Casimir amplitudes in topological quantum phase transitions.

    Science.gov (United States)

    Griffith, M A; Continentino, M A

    2018-01-01

    Topological phase transitions constitute a new class of quantum critical phenomena. They cannot be described within the usual framework of the Landau theory since, in general, the different phases cannot be distinguished by an order parameter, neither can they be related to different symmetries. In most cases, however, one can identify a diverging length at these topological transitions. This allows us to describe them using a scaling approach and to introduce a set of critical exponents that characterize their universality class. Here we consider some relevant models of quantum topological transitions associated with well-defined critical exponents that are related by a quantum hyperscaling relation. We extend to these models a finite-size scaling approach based on techniques for calculating the Casimir force in electromagnetism. This procedure allows us to obtain universal Casimir amplitudes at their quantum critical points. Our results verify the validity of finite-size scaling in these systems and confirm the values of the critical exponents obtained previously.

  15. Effective anisotropy through traveltime and amplitude matching

    KAUST Repository

    Wang, Hui

    2014-08-05

    Introducing anisotropy to seismic wave propagation reveals more realistic physics of our Earth\\'s subsurface as compared to the isotropic assumption. However wavefield modeling, the engine of seismic inverse problems, in anisotropic media still suffers from computational burdens, in particular with complex anisotropy such as transversely isotropic (TI) and Orthorhombic anisotropy. We develop effective isotropic velocity and density models to package the effects of anisotropy such that the wave propagation behavior using these effective models approximate those of the original anisotropic model. We build these effective models through the high frequency asymptotic approximation based on the eikonal and transport equations. We match the geometrical behavior of the wave-fields, given by traveltimes, from the anisotropic and isotropic eikonal equations. This matching yields the effective isotropic velocity that approximates the kinematics of the anisotropic wavefield. Equivalently, we calculate the effective densities by equating the anisotropic and isotropic transport equations. The effective velocities and densities are then fed into the isotropic acoustic variable density wave equation to obtain cheaper anisotropic wavefields. We justify our approach by testing it on an elliptical anisotropic model. The numerical results demonstrate a good matching of both traveltime and amplitude between anisotropic and effective isotropic wavefields.

  16. The pulsed amplitude unit for the SLC

    International Nuclear Information System (INIS)

    Rolfe, J.; Browne, M.J.; Jobe, R.K.

    1987-01-01

    There is a recurring requirement in the SLC for the control of devices such as magnets, phase shifters, and attenuators on a beam-by-beam basis. The Pulsed Amplitude Unit (PAU) is a single width CAMAC module developed for this purpose. It provides digitally programmed analog output voltages on a beam-by-beam basis. Up to 32 preprogrammed values of output voltage are available from the single analog output of the module, and any of these values can be associated with any of the 256 possible SLC beam definitions. A 12-bit Analog-to-Digital converter (ADC) digitizes an analog input signal at the appropriate beam time and stores it in a buffer memory. This feature is normally used to monitor the response of the device being controlled by the PAU at each beam time. Initial application of the PAU at is as part of the system that controls the output of Klystorns in the SLC. The PAU combines several different functions in a single module. In order to accommodate these functions in a single width CAMAC module, field programmed logic is used extensively. Field Programmable Logic Arrays, Programmed Array Logic, and a Field Programmable Logic Sequencer are employed

  17. Complex amplitude reconstruction by iterative amplitude-phase retrieval algorithm with reference

    Science.gov (United States)

    Shen, Cheng; Guo, Cheng; Tan, Jiubin; Liu, Shutian; Liu, Zhengjun

    2018-06-01

    Multi-image iterative phase retrieval methods have been successfully applied in plenty of research fields due to their simple but efficient implementation. However, there is a mismatch between the measurement of the first long imaging distance and the sequential interval. In this paper, an amplitude-phase retrieval algorithm with reference is put forward without additional measurements or priori knowledge. It gets rid of measuring the first imaging distance. With a designed update formula, it significantly raises the convergence speed and the reconstruction fidelity, especially in phase retrieval. Its superiority over the original amplitude-phase retrieval (APR) method is validated by numerical analysis and experiments. Furthermore, it provides a conceptual design of a compact holographic image sensor, which can achieve numerical refocusing easily.

  18. Transversity Amplitudes in Hypercharge Exchange Processes; Amplitudes de transversidad en procesos de intercambio de hipercarga

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar Benitez de Lugo, M.

    1979-07-01

    In this work we present several techniques developed for the extraction of the. Transversity amplitudes governing quasi two-body meson baryon reactions with hypercharge exchange. We review the methods used In processes having a pure spin configuration, as well as the more relevant results obtained with data from K{sup p} and Tp interactions at intermediate energies. The predictions of the additive quark model and the ones following from exchange degeneracy and etoxicity are discussed. We present a formalism for amplitude analysis developed for reactions with mixed spin configurations and discuss the methods of parametric estimation of the moduli and phases of.the amplitudes, as well as the various tests employed to check the goodness of the fits. The calculation of the generalized joint density matrices is given and we propose a method based on the generalization of the idea of multipole moments, which allows to investigate the structure of the decay angular correlations and establishes the quality of the fits and the validity of the simplifying assumptions currently used in this type of studies. (Author) 43 refs.

  19. SNAP-Ed (Supplemental Nutrition Assistance Program-Education) Increases Long-Term Food Security among Indiana Households with Children in a Randomized Controlled Study.

    Science.gov (United States)

    Rivera, Rebecca L; Maulding, Melissa K; Abbott, Angela R; Craig, Bruce A; Eicher-Miller, Heather A

    2016-11-01

    Food insecurity is negatively associated with US children's dietary intake and health. The Supplemental Nutrition Assistance Program-Education (SNAP-Ed) aims to alleviate food insecurity by offering nutrition, budgeting, and healthy lifestyle education to low-income individuals and families. The objective of this study was to evaluate the long-term impact of the Indiana SNAP-Ed on food security among households with children. A randomized, controlled, parallel study design with SNAP-Ed as an intervention was carried out during a 4- to 10-wk intervention period. Intervention group participants received the first 4 Indiana SNAP-Ed curriculum lessons. Study participants (n = 575) were adults aged ≥18 y from low-income Indiana households with ≥1 child living in the household. Both treatment groups completed an assessment before and after the intervention period and 1 y after recruitment. The 18-item US Household Food Security Survey Module was used to classify the primary outcomes of food security for the household and adults and children in the household. A linear mixed model was used to compare intervention with control group effects over time on food security. Mean ± SEM changes in household food security score and food security score among household adults from baseline to 1-y follow-up were 1.2 ± 0.4 and 0.9 ± 0.3 units lower, respectively, in the intervention group than in the control group (P security score from baseline to 1-y follow-up among household children was not significantly different in the intervention group compared with the control group. SNAP-Ed improved food security over a longitudinal time frame among low-income Indiana households with children in this study. SNAP-Ed may be a successful intervention to improve food security. © 2016 American Society for Nutrition.

  20. The Australian National Sub-acute and Non-acute Patient Casemix Classification (AN-SNAP): its application and value in a stroke rehabilitation programme.

    Science.gov (United States)

    Lowthian, P; Disler, P; Ma, S; Eagar, K; Green, J; de Graaff, S

    2000-10-01

    To investigate whether the Australian National Sub-acute and Non-acute Patient Casemix Classification (SNAP) and Functional Independence Measure and Functional Related Group (Version 2) (FIM-FRG2) casemix systems can be used to predict functional outcome, and reduce the variance of length of stay (LOS) of patients undergoing rehabilitation after strokes. The study comprised a retrospective analysis of the records of patients admitted to the Cedar Court Healthsouth Rehabilitation Hospital for rehabilitation after stroke. The sample included 547 patients (83.3% of those admitted with stroke during this period). Patient data were stratified for analysis into the five SNAP or nine FIM-FRG2 groups, on the basis of the admission FIM scores and age. The AN-SNAP classification accounted for a 30.7% reduction of the variance of LOS, and 44.2% of motor FIM, and the FIM-FRG2 accounts for 33.5% and 56.4% reduction respectively. Comparison of the Cedar Court with the national AN-SNAP data showed differences in the LOS and functional outcomes of older, severely disabled patients. Intensive rehabilitation in selected patients of this type appears to have positive effects, albeit with a slightly longer period of inpatient rehabilitation. Casemix classifications can be powerful management tools. Although FIM-FRG2 accounts for more reduction in variance than SNAP, division into nine groups meant that some contained few subjects. This paper supports the introduction of AN-SNAP as the standard casemix tool for rehabilitation in Australia, which will hopefully lead to rational, adequate funding of the rehabilitation phase of care.

  1. Scattering amplitudes in four- and six-dimensional gauge theories

    International Nuclear Information System (INIS)

    Schuster, Theodor

    2014-01-01

    We study scattering amplitudes in quantum chromodynamics (QCD), N=4 super Yang-Mills (SYM) theory and the six-dimensional N=(1,1) SYM theory, focusing on the symmetries of and relations between the tree-level scattering amplitudes in these three gauge theories. We derive the tree level and one-loop color decomposition of an arbitrary QCD amplitude into primitive amplitudes. Furthermore, we derive identities spanning the null space among the primitive amplitudes. We prove that every color ordered tree amplitude of massless QCD can be obtained from gluon-gluino amplitudes of N=4 SYM theory. Furthermore, we derive analytical formulae for all gluon-gluino amplitudes relevant for QCD. We compare the numerical efficiency and accuracy of evaluating these closed analytic formulae for color ordered QCD tree amplitudes to a numerically efficient implementation of the Berends-Giele recursion. We derive the symmetries of massive tree amplitudes on the coulomb branch of N=4 SYM theory, which in turn can be obtained from N=(1,1) SYM theory by dimensional reduction. Furthermore, we investigate the tree amplitudes of N=(1, 1) SYM theory and explain how analytical formulae can be obtained from a numerical implementation of the supersymmetric BCFW recursion relation and investigate a potential uplift of the massless tree amplitudes of N=4 SYM theory. Finally we study an alternative to dimensional regularization of N=4 SYM theory. The infrared divergences are regulated by masses obtained from a Higgs mechanism. The corresponding string theory set-up suggests that the amplitudes have an exact dual conformal symmetry. We confirm this expectation and illustrate the calculational advantages of the massive regulator by explicit calculations.

  2. Ocular pulse amplitude after panretinal photocoagulation in normotensive eyes with proliferative diabetic retinopathy.

    Science.gov (United States)

    Bozic, Marija M; Karadzic, Jelena B; Kovacevic, Igor M; Marjanovic, Ivan S

    2017-06-26

    To assess the effect of panretinal laser photocoagulation on ocular pulse amplitude (OPA) in normotensive eyes with proliferative diabetic retinopathy. Prospectively, we performed unilateral argon laser panretinal photocoagulation (PRP) in 30 patients with diabetes mellitus type II and previously untreated bilateral proliferative diabetic retinopathy. Before and 7 and 30 days after the treatment, OPA was measured using dynamic contour tonometer. Compared with the untreated contralateral eyes, laser photocoagulation led to a reduction of OPA. Ocular pulse amplitude did not significantly differ in photocoagulated eyes 7 days after the treatment, but there was a significant difference in OPA 30 days after the treatment. The decrease in OPA values was 15% 7 days after PRP and 40% 30 days after PRP. Ocular pulse amplitude reduction after PRP indirectly informs us about choriocapillary closure, already reported in previous studies.

  3. Responses to amplitude modulated infrared stimuli in the guinea pig inferior colliculus

    Science.gov (United States)

    Richter, Claus-Peter; Young, Hunter

    2013-03-01

    Responses of units in the central nucleus of the inferior colliculus of the guinea pig were recorded with tungsten electrodes. The set of data presented here is limited to high stimulus levels. The effect of changing the modulation frequency and the modulation depth was explored for acoustic and laser stimuli. The selected units responded to sinusoidal amplitude modulated (AM) tones, AM trains of clicks, and AM trains of laser pulses with a modulation of their spike discharge. At modulation frequencies of 20 Hz, some units tended to respond with 40 Hz to the acoustic stimuli, but only at 20 Hz for the trains of laser pulses. For all modes of stimulation the responses revealed a dominant response to the first cycle of the modulation, with decreasing number of action potential during successive cycles. While amplitude modulated tone bursts and amplitude modulated trains of acoustic clicks showed similar patterns, the response to trains of laser pulses was different.

  4. Amplitude growth due to random, correlated kicks

    International Nuclear Information System (INIS)

    Michelotti, L.; Mills, F.

    1989-03-01

    Historically, stochastic processes, such as gas scattering or stochastic cooling, have been treated by the Fokker-Planck equation. In this approach, usually considered for one dimension only, the equation can be considered as a continuity equation for a variable which would be a constant of the motion in the absence of the stochastic process, for example, the action variable, I = ε/2π for betatron oscillations, where ε is the area of the Courant-Snyder ellipse, or energy in the case of unbunched beams, or the action variable for phase oscillations in case the beam is bunched. A flux, /Phi/, including diffusive terms can be defined, usually to second order. /Phi/ = M 1 F(I) + M 2 ∂F/∂I + /hor ellipsis/. M 1 and M 2 are the expectation values of δI and (δI) 2 due to the individual stochastic kicks over some period of time, long enough that the variance of these quantities is sufficiently small. Then the Fokker-Planck equation is just ∂F/∂I + ∂/Phi//∂I = 0. In many cases those where the beam distribution has already achieved its final shape, it is sufficient to find the rate of increase of by taking simple averages over the Fokker-Planck equation. At the time this work was begun, there was good knowledge of the second moment for general stochastic processes due to stochastic cooling theory, but the form of the first moment was known only for extremely wideband processes. The purposes of this note are to derive an expression relating the expected single particle amplitude growth to the noise autocorrelation function and to obtain, thereby, the form of M 1 for narrow band processes. 4 refs

  5. When is respiratory management necessary for partial breast intensity modulated radiotherapy: A respiratory amplitude escalation treatment planning study

    International Nuclear Information System (INIS)

    Quirk, Sarah; Conroy, Leigh; Smith, Wendy L.

    2014-01-01

    Purpose: The impact of typical respiratory motion amplitudes (∼2 mm) on partial breast irradiation (PBI) is minimal; however, some patients have larger respiratory amplitudes that may negatively affect dose homogeneity. Here we determine at what amplitude respiratory management may be required to maintain plan quality. Methods and Materials: Ten patients were planned with PBI IMRT. Respiratory motion (2–20 mm amplitude) probability density functions were convolved with static plan fluence to estimate the delivered dose. Evaluation metrics included target coverage, ipsilateral breast hotspot, homogeneity, and uniformity indices. Results: Degradation of dose homogeneity was the limiting factor in reduction of plan quality due to respiratory motion, not loss of coverage. Hotspot increases were observed even at typical motion amplitudes. At 2 and 5 mm, 2/10 plans had a hotspot greater than 107% and at 10 mm this increased to 5/10 plans. Target coverage was only compromised at larger amplitudes: 5/10 plans did not meet coverage criteria at 15 mm amplitude and no plans met minimum coverage at 20 mm. Conclusions: We recommend that if respiratory amplitude is greater than 10 mm, respiratory management or alternative radiotherapy should be considered due to an increase in the hotspot in the ipsilateral breast and a decrease in dose homogeneity

  6. Effects of Administration of Perinatal Bupropion on the Population Spike Amplitude in Neonatal Rat Hippocampal Slice

    Directory of Open Access Journals (Sweden)

    Soomaayeh Heysieat-talab

    2010-09-01

    Full Text Available Objective(sBupropion is an atypical antidepressant that is widely used in smoke cessation under FDA approval. The study of synaptic effects of bupropion can help to finding out its mechanism(s for stopping nicotine dependence. In this study the effects of perinatal bupropion on the population spike (PS amplitude of neonates were investigated. Materials and Methods Hippocampal slices were prepared from 18-25 days old rat pups. The experimental groups included control and bupropion-treated. Bupropion (40 mg/Kg, i.p. was applied daily in perinatal period as pre-treatment. Due to the studying acute effects, bupropion was also added to the perfusion medium (10, 50, 200 μM for 30 min. The evoked PS was recorded from pyramidal layer of CA1 area, following stimulation of Schaffer collaterals. ResultsA concentration of 10 μM bupropion had no significant effects on the PS amplitude. The 50 μM concentration of bupropion reduced the amplitude of responses in 50% of the studied cases. At a concentration of 200 μM, the recorded PS amplitudes were reduced in all slices (n= 22. Amplitude was completely abolished in 8 out of the 22 slices. The decrease of the PS amplitude was found to be more in the non-pre-treated slices than in the pre-treated slices when both were perfused with 200 μM bupropion.Conclusion The results showed the perinatal exposure to bupropion and its acute effects while indicating that at concentrations of 50 and 200 μM bupropion reduced the PS amplitude. It was also found that there was evidence of synaptic adaptation in comparison of bupropion-treated and non-treated slices whereas they were both perfused with 200 µM.

  7. Atrazine alters expression of reproductive and stress genes in the developing hypothalamus of the snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Russart, Kathryn L G; Rhen, Turk

    2016-07-29

    Atrazine is an herbicide used to control broadleaf grasses and a suspected endocrine disrupting chemical. Snapping turtles lay eggs between late May and early June, which could lead to atrazine exposure via field runoff. Our goal was to determine whether a single exposure to 2ppb or 40ppb atrazine during embryogenesis could induce short- and long-term changes in gene expression within the hypothalamus of snapping turtles. We treated eggs with atrazine following sex determination and measured gene expression within the hypothalamus. We selected genes a priori for their role in the hypothalamus-pituitary-gonad or the hypothalamus-pituitary-adrenal axes of the endocrine system. We did not identify any changes in gene expression 24-h after treatment. However, at hatching AR, Kiss1R, and POMC expression was upregulated in both sexes, while expression of CYP19A1 and PDYN was increased in females. Six months after hatching, CYP19A1 and PRLH expression was increased in animals treated with 2ppb atrazine. Our study shows persistent changes in hypothalamic gene expression due to low-dose embryonic exposure to the herbicide atrazine with significant effects in both the HPG and HPA axes. Effects reported here appear to be conserved among vertebrates. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  8. Proteome stability analysis of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human colon mucosal biopsies

    Directory of Open Access Journals (Sweden)

    Tue Bjerg Bennike

    2016-03-01

    Full Text Available Large repositories of well characterized RNAlater preserved samples and formalin-fixed, paraffin-embedded samples have been generated worldwide. However, the impact on the proteome of the preservation methods remain poorly described. Therefore, we analyzed the impact on the proteome of preserving samples in RNAlater, and by formalin-fixation, paraffin-embedding on human soft tissue, using directly frozen samples as a control (“Comparing the proteome of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human tissue samples” [1]. We here report the data from the analysis. The comparative analysis was performed on 24 colon mucosa biopsies, extracted from the sigmoideum of two gastroenterologically healthy participants for the purpose of this study. A set of biopsies were additionally stored for 30 min at room temperature prior to formalin-fixation. The samples were analyzed by high throughput gel free quantitative proteomics. The MS proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PRIDE: http://www.ebi.ac.uk/pride/archive/projects/PXD002029. Keywords: Human, Colon, Mucosa, RNAlater, FFPE, Snap-frozen, Stability, LC–MS, Proteomics

  9. Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.

    Directory of Open Access Journals (Sweden)

    Rahman M Mizanur

    Full Text Available Various substrates, catalysts, and assay methods are currently used to screen inhibitors for their effect on the proteolytic activity of botulinum neurotoxin. As a result, significant variation exists in the reported results. Recently, we found that one source of variation was the use of various catalysts, and have therefore evaluated its three forms. In this paper, we characterize three substrates under near uniform reaction conditions using the most active catalytic form of the toxin. Bovine serum albumin at varying optimum concentrations stimulated enzymatic activity with all three substrates. Sodium chloride had a stimulating effect on the full length synaptosomal-associated protein of 25 kDa (SNAP25 and its 66-mer substrates but had an inhibitory effect on the 17-mer substrate. We found that under optimum conditions, full length SNAP25 was a better substrate than its shorter 66-mer or 17-mer forms both in terms of kcat, Km, and catalytic efficiency kcat/Km. Assay times greater than 15 min introduced large variations and significantly reduced the catalytic efficiency. In addition to characterizing the three substrates, our results identify potential sources of variations in previous published results, and underscore the importance of using well-defined reaction components and assay conditions.

  10. Relative amplitude preservation processing utilizing surface consistent amplitude correction. Part 4; Surface consistent amplitude correction wo mochiita sotai shinpuku hozon shori. 4

    Energy Technology Data Exchange (ETDEWEB)

    Saeki, T [Japan National Oil Corp., Tokyo (Japan). Technology Research Center

    1997-10-22

    Discussions were given on seismic exploration from the ground surface using the reflection method, for surface consistent amplitude correction from among effects imposed from the ground surface and a surface layer. Amplitude distribution on the reflection wave zone is complex. Therefore, items to be considered in making an analysis are multiple, such as estimation of spherical surface divergence effect and exponential attenuation effect, not only amplitude change through the surface layer. If all of these items are taken into consideration, burden of the work becomes excessive. As a method to solve this problem, utilization of amplitude in initial movement of a diffraction wave may be conceived. Distribution of the amplitude in initial movement of the diffraction wave shows a value relatively close to distribution of the vibration transmitting and receiving points. The reason for this is thought because characteristics of the vibration transmitting and receiving points related with waveline paths in the vicinity of the ground surface have no great difference both on the diffraction waves and on the reflection waves. The lecture described in this paper introduces an attempt of improving the efficiency of the surface consistent amplitude correction by utilizing the analysis of amplitude in initial movement of the diffraction wave. 4 refs., 2 figs.

  11. Analyticity properties of two-body helicity amplitudes; Proprietes d'analyticite des amplitudes d'helicite a deux corps

    Energy Technology Data Exchange (ETDEWEB)

    Navelet-Noualhier, H [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-06-15

    Helicity amplitudes are expressed via the spinor amplitudes in terms of the Joos invariant which have been shown by Williams to be free from kinematical singularities. This procedure allows to analyze the kinematical singularities of helicity amplitudes and separate them out, which results into the definition of regularized helicity amplitudes. A crossing matrix for helicity amplitudes, is written down, corresponding to the continuation path used to cross spinor amplitudes. We verify explicitly that the corresponding crossing matrix for regularized helicity amplitudes is uniform as it should be. Kinematical constraints which generalize, to the case of arbitrary spins and masses, relations which must hold between helicity amplitudes at some values of the energy variable in {pi}N {yields} {pi}N, {pi}{pi} {yields} NN-bar and NN-bar {yields} NN-bar reactions, appear as a consequence of the existence of poles in the crossing matrix between regularized helicity amplitudes. An english version of this work has been written with G. Cohen-Tannoudji and A. Morel and submitted for publication to Annals of Physics. (author) [French] Les amplitudes d'helicite pour une reaction a deux corps sont exprimees, par l'intermediaire des amplitudes spinorielles, en fonction d'amplitudes invariantes de Joos qui sont, comme l'a montre Williams, sans singularites cinematiques. Ce procede nous permet d'analyser puis d'eliminer les singularites cinematiques des amplitudes d'helicite. Ceci nous conduit a la definition d'amplitudes d'helicite 'regularisees'. Une relation de 'croisement' entre amplitudes d'helicite est ecrite; elle realise leur prolongement analytique le long du chemin utilise pour 'croiser' les amplitudes spinorielles. Nous verifions que les elements de la matrice de croisement entre amplitudes d'helicite 'regularisees' sont bien uniformes. Les contraintes cinematiques qui generalisent, au cas de masses et de spins arbitraires, les relations obtenues dans les reactions {pi

  12. Adjusting Pulse Amplitude During Transcutaneous Electrical Nerve Stimulation Does Not Provide Greater Hypoalgesia.

    Science.gov (United States)

    Bergeron-Vézina, Kayla; Filion, Camille; Couture, Chantal; Vallée, Élisabeth; Laroche, Sarah; Léonard, Guillaume

    2018-03-01

    Transcutaneous electrical nerve stimulation (TENS) is an electrotherapeutic modality commonly used in rehabilitation to relieve pain. Adjusting pulse amplitude (intensity) during TENS treatment has been suggested to overcome nerve habituation. However, it is still unclear if this procedure leads to greater hypoalgesia. The aim of this study was to determine if the hypoalgesic effect of TENS is greater when pulse amplitude is adjusted throughout the TENS treatment session in chronic low-back pain patients. Randomized double-blind crossover study. Recruitment and assessment were conducted at the Clinique universitaire de réadaptation de l'Estrie (CURE) of the Faculty of Medicine and Health Sciences of the Université de Sherbrooke. Twenty-one volunteers with chronic low-back pain were enrolled and completed this investigation. Each patient received two high-frequency TENS treatments on two separate sessions: (1) with adjustment of pulse amplitude and (2) without pulse amplitude adjustment. Pain intensity and unpleasantness were assessed before, during, and after TENS application with a 10 cm visual analog scale. Both TENS conditions (with and without adjustment of intensity) decreased pain intensity and unpleasantness when compared with baseline. No difference was observed between the two stimulation conditions for both pain intensity and unpleasantness. The current results suggest that adjustment of pulse amplitude during TENS application does not provide greater hypoalgesia in individuals with chronic low-back pain. Future studies are needed to confirm these findings in other pain populations.

  13. Eikonal representation of N-body Coulomb scattering amplitudes

    International Nuclear Information System (INIS)

    Fried, H.M.; Kang, K.; McKellar, B.H.J.

    1983-01-01

    A new technique for the construction of N-body Coulomb scattering amplitudes is proposed, suggested by the simplest case of N = 2: Calculate the scattering amplitude in eikonal approximation, discard the infinite phase factors which appear upon taking the limit of a Coulomb potential, and treat the remainder as an amplitude whose absolute value squared produces the exact, Coulomb differential cross section. The method easily generalizes to the N-body Coulomb problem for elastic scattering, and for inelastic rearrangement scattering of Coulomb bound states. We give explicit results for N = 3 and 4; in the N = 3 case we extract amplitudes for the processes (12)+3->1+2+3 (breakup), (12)+3->1+(23) (rearrangement), and (12)+3→(12)'+3 (inelastic scattering) as residues at the appropriate poles in the free-free amplitude. The method produces scattering amplitudes f/sub N/ given in terms of explicit quadratures over (N-2) 2 distinct integrands

  14. Expansion of all multitrace tree level EYM amplitudes

    Science.gov (United States)

    Du, Yi-Jian; Feng, Bo; Teng, Fei

    2017-12-01

    In this paper, we investigate the expansion of tree level multitrace Einstein-Yang-Mills (EYM) amplitudes. First, we propose two types of recursive expansions of tree level EYM amplitudes with an arbitrary number of gluons, gravitons and traces by those amplitudes with fewer traces or/and gravitons. Then we give many support evidence, including proofs using the Cachazo-He-Yuan (CHY) formula and Britto-Cachazo-Feng-Witten (BCFW) recursive relation. As a byproduct, two types of generalized BCJ relations for multitrace EYM are further proposed, which will be useful in the BCFW proof. After one applies the recursive expansions repeatedly, any multitrace EYM amplitudes can be given in the Kleiss-Kuijf (KK) basis of tree level color ordered Yang-Mills (YM) amplitudes. Thus the Bern-Carrasco-Johansson (BCJ) numerators, as the expansion coefficients, for all multitrace EYM amplitudes are naturally constructed.

  15. Tensor exchange amplitudes in K +- N charge exchange reactions

    International Nuclear Information System (INIS)

    Svec, M.

    1979-01-01

    Tensor (A 2 ) exchange amplitudes in K +- N charge exchange (CEX) are constructed from the K +- N CEX data supplemented by information on the vector (rho) exchange amplitudes from πN sca tering. We observed new features in the t-structure of A 2 exchange amplitudes which contradict the t-de pendence anticipated by most of the Regge models. The results also provide evidence for violation of weak exchange degeneracy

  16. Loop Amplitudes in Pure Yang-Mills from Generalised Unitarity

    OpenAIRE

    Brandhuber, Andreas; McNamara, Simon; Spence, Bill; Travaglini, Gabriele

    2005-01-01

    We show how generalised unitarity cuts in D = 4 - 2 epsilon dimensions can be used to calculate efficiently complete one-loop scattering amplitudes in non-supersymmetric Yang-Mills theory. This approach naturally generates the rational terms in the amplitudes, as well as the cut-constructible parts. We test the validity of our method by re-deriving the one-loop ++++, -+++, --++, -+-+ and +++++ gluon scattering amplitudes using generalised quadruple cuts and triple cuts in D dimensions.

  17. Loop amplitudes in pure Yang-Mills from generalised unitarity

    International Nuclear Information System (INIS)

    Brandhuber, Andreas; McNamara, Simon; Spence, Bill; Travaglini, Gabriele

    2005-01-01

    We show how generalised unitarity cuts in D = 4-2ε dimensions can be used to calculate efficiently complete one-loop scattering amplitudes in non-supersymmetric Yang-Mills theory. This approach naturally generates the rational terms in the amplitudes, as well as the cut-constructible parts. We test the validity of our method by re-deriving the one-loop ++++, -+++, --++, -+-+ and +++++ gluon scattering amplitudes using generalised quadruple cuts and triple cuts in D dimensions

  18. Loop amplitudes in pure Yang-Mills from generalised unitarity

    Energy Technology Data Exchange (ETDEWEB)

    Brandhuber, Andreas [Department of Physics, Queen Mary, University of London, Mile End Road, London, E1 4NS (United Kingdom); McNamara, Simon [Department of Physics, Queen Mary, University of London, Mile End Road, London, E1 4NS (United Kingdom); Spence, Bill [Department of Physics, Queen Mary, University of London, Mile End Road, London, E1 4NS (United Kingdom); Travaglini, Gabriele [Department of Physics, Queen Mary, University of London, Mile End Road, London, E1 4NS (United Kingdom)

    2005-10-15

    We show how generalised unitarity cuts in D = 4-2{epsilon} dimensions can be used to calculate efficiently complete one-loop scattering amplitudes in non-supersymmetric Yang-Mills theory. This approach naturally generates the rational terms in the amplitudes, as well as the cut-constructible parts. We test the validity of our method by re-deriving the one-loop ++++, -+++, --++, -+-+ and +++++ gluon scattering amplitudes using generalised quadruple cuts and triple cuts in D dimensions.

  19. Calculation and modular properties of multiloop superstring amplitudes

    International Nuclear Information System (INIS)

    Danilov, G. S.

    2013-01-01

    Multiloop superstring amplitudes are calculated within an extensively used gauge where the two-dimensional gravitino field carries Grassmann moduli. In general, the amplitudes possess, instead of modular symmetry, symmetry with respect to modular transformation supplemented with appropriate transformations of two-dimensional local supersymmetry. If the number of loops is larger than three, the integrationmeasures are notmodular forms, while the expression for the amplitude contains integrals along the boundary of the fundamental region of the modular group.

  20. Efficient analytic computation of higher-order QCD amplitudes

    International Nuclear Information System (INIS)

    Bern, Z.; Chalmers, G.; Dunbar, D.C.; Kosower, D.A.

    1995-01-01

    The authors review techniques simplifying the analytic calculation of one-loop QCD amplitudes with many external legs, for use in next-to-leading-order corrections to multi-jet processes. Particularly useful are the constraints imposed by perturbative unitarity, collinear singularities and a supersymmetry-inspired organization of helicity amplitudes. Certain sequences of one-loop helicity amplitudes with an arbitrary number of external gluons have been obtained using these constraints

  1. Improved pion pion scattering amplitude from dispersion relation formalism

    International Nuclear Information System (INIS)

    Cavalcante, I.P.; Coutinho, Y.A.; Borges, J. Sa

    2005-01-01

    Pion-pion scattering amplitude is obtained from Chiral Perturbation Theory at one- and two-loop approximations. Dispersion relation formalism provides a more economic method, which was proved to reproduce the analytical structure of that amplitude at both approximation levels. This work extends the use of the formalism in order to compute further unitarity corrections to partial waves, including the D-wave amplitude. (author)

  2. Ambitwistor strings and reggeon amplitudes in N=4 SYM

    Directory of Open Access Journals (Sweden)

    L.V. Bork

    2017-11-01

    Full Text Available We consider the description of reggeon amplitudes (Wilson lines form factors in N=4 SYM within the framework of four dimensional ambitwistor string theory. The latter is used to derive scattering equations representation for reggeon amplitudes with multiple reggeized gluons present. It is shown, that corresponding tree-level string correlation function correctly reproduces previously obtained Grassmannian integral representation of reggeon amplitudes in N=4 SYM.

  3. The five-gluon amplitude and one-loop integrals

    International Nuclear Information System (INIS)

    Bern, Z.; Dixon, L.; Kosower, D.A.

    1992-12-01

    We review the conventional field theory description of the string motivated technique. This technique is applied to the one-loop five-gluon amplitude. To evaluate the amplitude a general method for computing dimensionally regulated one-loop integrals is outlined including results for one-loop integrals required for the pentagon diagram and beyond. Finally, two five-gluon helicity amplitudes are given

  4. Renormalization in the complete Mellin representation of Feynman amplitudes

    International Nuclear Information System (INIS)

    Calan, C. de; David, F.; Rivasseau, V.

    1981-01-01

    The Feynmann amplitudes are renormalized in the formalism of the CM representation. This Mellin-Barnes type integral representation, previously introduced for the study of asymptotic behaviours, is shown to have the following interesting property: in contrast with the usual subtraction procedures, the renormalization leaves the CM intergrand unchanged, and only results into translations of the integration path. The explicit CM representation of the renormalized amplitudes is given. In addition, the dimensional regularization and the extension to spinor amplitudes are sketched. (orig.)

  5. Algebraic evaluation of rational polynomials in one-loop amplitudes

    International Nuclear Information System (INIS)

    Binoth, Thomas; Guillet, Jean-Philippe; Heinrich, Gudrun

    2007-01-01

    One-loop amplitudes are to a large extent determined by their unitarity cuts in four dimensions. We show that the remaining rational terms can be obtained from the ultraviolet behaviour of the amplitude, and determine universal form factors for these rational parts by applying reduction techniques to the Feynman diagrammatic representation of the amplitude. The method is valid for massless and massive internal particles. We illustrate this method by evaluating the rational terms of the one-loop amplitudes for gg→H, γγ→γγ, gg→gg,γγ→ggg and γγ→γγγγ

  6. Phase and amplitude control system for Stanford Linear Accelerator

    International Nuclear Information System (INIS)

    Yoo, S.J.

    1983-01-01

    The computer controlled phase and amplitude detection system measures the instantaneous phase and amplitude of a 1 micro-second 2856 MHz rf pulse at a 180 Hz rate. This will be used for phase feedback control, and also for phase and amplitude jitter measurement. The program, which was originally written by John Fox and Keith Jobe, has been modified to improve the function of the system. The software algorithms used in the measurement are described, as is the performance of the prototype phase and amplitude detector system

  7. New rigorous asymptotic theorems for inverse scattering amplitudes

    International Nuclear Information System (INIS)

    Lomsadze, Sh.Yu.; Lomsadze, Yu.M.

    1984-01-01

    The rigorous asymptotic theorems both of integral and local types obtained earlier and establishing logarithmic and in some cases even power correlations aetdeen the real and imaginary parts of scattering amplitudes Fsub(+-) are extended to the inverse amplitudes 1/Fsub(+-). One also succeeds in establishing power correlations of a new type between the real and imaginary parts, both for the amplitudes themselves and for the inverse ones. All the obtained assertions are convenient to be tested in high energy experiments when the amplitudes show asymptotic behaviour

  8. Proof of the fundamental BCJ relations for QCD amplitudes

    International Nuclear Information System (INIS)

    Cruz, Leonardo de la; Kniss, Alexander; Weinzierl, Stefan

    2015-01-01

    The fundamental BCJ-relation is a linear relation between primitive tree amplitudes with different cyclic orderings. The cyclic orderings differ by the insertion place of one gluon. The coefficients of the fundamental BCJ-relation are linear in the Lorentz invariants 2p_ip_j. The BCJ-relations are well established for pure gluonic amplitudes as well as for amplitudes in N=4 super-Yang-Mills theory. Recently, it has been conjectured that the BCJ-relations hold also for QCD amplitudes. In this paper we give a proof of this conjecture. The proof is valid for massless and massive quarks.

  9. Amplitude dependent damping in single crystalline high purity molybdenum

    International Nuclear Information System (INIS)

    Zelada-Lambri, G.I; Lambri, O.A; Garcia, J.A; Lomer, J.N

    2004-01-01

    Amplitude dependent damping measurements were performed on high purity single crystalline molybdenum at several different constant temperatures between room temperature and 1273K. The employed samples were single crystals with the orientation, having a residual resistivity ratio of about 8000. Previously to the amplitude dependent damping tests, the samples were subjected to different thermomechanical histories. Amplitude dependent damping effects appear only during the first heating run in temperature where the samples have the thermomechanical state of the deformation process at room temperature. In the subsequent run-ups in temperature, i.e, after subsequent annealings, amplitude dependent damping effects were not detected (au)

  10. Analytical structure of the 3. -->. 3 forward scattering amplitude

    Energy Technology Data Exchange (ETDEWEB)

    Logunov, A A; Medvedev, B V; Muzafarov, L M; Pavlov, V P; Polivanov, M K; Sukhanov, A D [AN SSSR, Moscow. Matematicheskij Inst.

    1979-08-01

    Analytical properties of the amplitude of 3..-->..3 forward scattering established in the framework of the Bogolyubov axiomatic approach are described. The amplitudes of the different channels of the process are boundary values of a unique analytical function of invariant variables. Crossing-symmetry property of the amplitude is proved. Analysis of the absorptive part of the amplitude is performed and the generalized optical theorem is proved which connects one of the contributions into the absorptive part with the distribution function of the inclusive process.

  11. Generalized unitarity for N=4 super-amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, J.M.; Henn, J. [LAPTH, Université de Savoie, CNRS B.P. 110, F-74941 Annecy-le-Vieux Cedex (France); Korchemsky, G.P., E-mail: Gregory.Korchemsky@cea.fr [Institut de Physique Théorique, CEA Saclay, 91191 Gif-sur-Yvette Cedex (France); Sokatchev, E. [LAPTH, Université de Savoie, CNRS B.P. 110, F-74941 Annecy-le-Vieux Cedex (France)

    2013-04-21

    We develop a manifestly supersymmetric version of the generalized unitarity cut method for calculating scattering amplitudes in N=4 SYM theory. We illustrate the power of this method by computing the one-loop n-point NMHV super-amplitudes. The result confirms two conjectures which we made in Drummond, et al., [1]. Firstly, we derive the compact, manifestly dual superconformally covariant form of the NMHV tree amplitudes for arbitrary number and types of external particles. Secondly, we show that the ratio of the one-loop NMHV to the MHV amplitude is dual conformal invariant.

  12. Tree-level amplitudes and dual superconformal symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, J M, E-mail: drummond@lapp.in2p3.fr [PH-TH Division, CERN, CH-1211, Geneva 23 (Switzerland); LAPTH, Universite de Savoie, CNRS, B.P. 110, F-74941 Annecy-le-Vieux Cedex (France)

    2011-11-11

    We review the structure of gauge theory scattering amplitudes at tree level and describe how a compact expression can be found which encodes all the tree-level amplitudes in the maximally supersymmetric N=4 theory. The expressions for the amplitudes reveal a dual superconformal symmetry. We describe how these ideas can be extended to leading singularities and the loop integrand in the planar theory and discuss the appearance of dual conformal symmetry in higher-dimensional gauge theories. This paper is an invited review for a special issue of Journal of Physics A: Mathematical and Theoretical devoted to 'Scattering amplitudes in gauge theories'. (review)

  13. New relations for Einstein–Yang–Mills amplitudes

    International Nuclear Information System (INIS)

    Stieberger, Stephan; Taylor, Tomasz R.

    2016-01-01

    We obtain new relations between Einstein–Yang–Mills (EYM) amplitudes involving N gauge bosons plus a single graviton and pure Yang–Mills amplitudes involving N gauge bosons plus one additional vector boson inserted in a way typical for a gauge boson of a “spectator” group commuting with the group associated to original N gauge bosons. We show that such EYM amplitudes satisfy U(1) decoupling relations similar to Kleiss–Kuijf relations for Yang–Mills amplitudes. We consider a D-brane embedding of EYM amplitudes in the framework of disk amplitudes involving open and closed strings. A new set of monodromy relations is derived for mixed open–closed amplitudes with one closed string inserted on the disk world-sheet and a number of open strings at the boundary. These relations allow expressing the latter in terms of pure open string amplitudes and, in the field-theory limit, they yield the U(1) decoupling relations for EYM amplitudes.

  14. Smooth Pursuit Saccade Amplitude Modulation During Exposure to Microgravity

    Science.gov (United States)

    Reschke, M. F.; Kozlovskaya, I. B.; Sayenko, D. G.; Sayenko, I.; Somers, J. T.; Paloski, W. H.

    2002-01-01

    Russian investigators have reported changes in pursuit tracking of a vertically moving point stimulus during space flight. Early in microgravity, changes were manifested by decreased eye movement amplitude (undershooting) and the appearance of correction saccades. As the flight progressed, pursuit of the moving point stimulus deteriorated while associated saccadic movements were unchanged. Immediately postflight there was an improved execution of active head movements indicating that the deficiencies in pursuit function noted in microgravity may be of central origin. In contrast, tests of two cosmonauts showed that horizontal and vertical smooth pursuit were unchanged inflight. However, results of corresponding saccadic tasks showed a tendency toward the overshooting of a horizontal target early inflight with high accuracy developing later inflight, accompanied by an increased saccade velocity and a trend toward decreased saccade latency. Based on these equivocal results, we have further investigated the effects of space flight on the smooth pursuit mechanism during and after short duration flight, and postflight on returning MIR crewmembers. Sinusoidal target movement was presented horizontally at frequencies of 0.33 and 1.0 Hz. Subjects were asked to perform two trials for each stimulus combination: (1) moving eyes-only (EO) and (2) moving eyes and head (EH) with the target motion. Peak amplitude was 30 deg for 0.33 Hz trials and 15 deg for the 1.0 Hz trials. The relationship between saccade amplitude and peak velocity were plotted as a main sequence for each phase of flight, and linear regression analysis allowed us to determine the slope of each main sequence plot. The linear slopes were then combined for each flight phase for each individual subject. The main sequence for both EO and EH trials at both the 0.33 and 1.0 Hz frequencies during flight for the short duration flyers showed a reduction in saccade velocity and amplitude when compared to the preflight

  15. Source-Space Cross-Frequency Amplitude-Amplitude Coupling in Tinnitus

    Directory of Open Access Journals (Sweden)

    Oliver Zobay

    2015-01-01

    Full Text Available The thalamocortical dysrhythmia (TCD model has been influential in the development of theoretical explanations for the neurological mechanisms of tinnitus. It asserts that thalamocortical oscillations lock a region in the auditory cortex into an ectopic slow-wave theta rhythm (4–8 Hz. The cortical area surrounding this region is hypothesized to generate abnormal gamma (>30 Hz oscillations (“edge effect” giving rise to the tinnitus percept. Consequently, the model predicts enhanced cross-frequency coherence in a broad range between theta and gamma. In this magnetoencephalography study involving tinnitus and control cohorts, we investigated this prediction. Using beamforming, cross-frequency amplitude-amplitude coupling (AAC was computed within the auditory cortices for frequencies (f1,f2 between 2 and 80 Hz. We find the AAC signal to decompose into two distinct components at low (f1,f230 Hz frequencies, respectively. Studying the correlation of AAC with several key covariates (age, hearing level (HL, tinnitus handicap and duration, and HL at tinnitus frequency, we observe a statistically significant association between age and low-frequency AAC. Contrary to the TCD predictions, however, we do not find any indication of statistical differences in AAC between tinnitus and controls and thus no evidence for the predicted enhancement of cross-frequency coupling in tinnitus.

  16. True amplitude wave equation migration arising from true amplitude one-way wave equations

    Science.gov (United States)

    Zhang, Yu; Zhang, Guanquan; Bleistein, Norman

    2003-10-01

    One-way wave operators are powerful tools for use in forward modelling and inversion. Their implementation, however, involves introduction of the square root of an operator as a pseudo-differential operator. Furthermore, a simple factoring of the wave operator produces one-way wave equations that yield the same travel times as the full wave equation, but do not yield accurate amplitudes except for homogeneous media and for almost all points in heterogeneous media. Here, we present augmented one-way wave equations. We show that these equations yield solutions for which the leading order asymptotic amplitude as well as the travel time satisfy the same differential equations as the corresponding functions for the full wave equation. Exact representations of the square-root operator appearing in these differential equations are elusive, except in cases in which the heterogeneity of the medium is independent of the transverse spatial variables. Here, we address the fully heterogeneous case. Singling out depth as the preferred direction of propagation, we introduce a representation of the square-root operator as an integral in which a rational function of the transverse Laplacian appears in the integrand. This allows us to carry out explicit asymptotic analysis of the resulting one-way wave equations. To do this, we introduce an auxiliary function that satisfies a lower dimensional wave equation in transverse spatial variables only. We prove that ray theory for these one-way wave equations leads to one-way eikonal equations and the correct leading order transport equation for the full wave equation. We then introduce appropriate boundary conditions at z = 0 to generate waves at depth whose quotient leads to a reflector map and an estimate of the ray theoretical reflection coefficient on the reflector. Thus, these true amplitude one-way wave equations lead to a 'true amplitude wave equation migration' (WEM) method. In fact, we prove that applying the WEM imaging condition

  17. Temporal-spatial characteristics of phase-amplitude coupling in electrocorticogram for human temporal lobe epilepsy.

    Science.gov (United States)

    Zhang, Ruihua; Ren, Ye; Liu, Chunyan; Xu, Na; Li, Xiaoli; Cong, Fengyu; Ristaniemi, Tapani; Wang, YuPing

    2017-09-01

    Neural activity of the epileptic human brain contains low- and high-frequency oscillations in different frequency bands, some of which have been used as reliable biomarkers of the epileptogenic brain areas. However, the relationship between the low- and high-frequency oscillations in different cortical areas during the period from pre-seizure to post-seizure has not been completely clarified. We recorded electrocorticogram data from the temporal lobe and hippocampus of seven patients with temporal lobe epilepsy. The modulation index based on the Kullback-Leibler distance and the phase-amplitude coupling co-modulogram were adopted to quantify the coupling strength between the phase of low-frequency oscillations (0.2-10Hz) and the amplitude of high-frequency oscillations (11-400Hz) in different seizure epochs. The time-varying phase-amplitude modulogram was used to analyze the phase-amplitude coupling pattern during the entire period from pre-seizure to post-seizure in both the left and right temporal lobe and hippocampus. Channels with strong modulation index were compared with the seizure onset channels identified by the neurosurgeons and the resection channels in the clinical surgery. The phase-amplitude coupling strength (modulation index) increased significantly in the mid-seizure epoch and decrease significantly in seizure termination and post-seizure epochs (ptemporal cortex and hippocampus. The "fall-max" phase-amplitude modulation pattern, i.e., high-frequency amplitudes were largest in the low-frequency phase range [-π, 0], which corresponded to the falling edges of low-frequency oscillations, appeared in the middle period of the seizures at epileptic focus channels. Channels with strong modulation index appeared on the corresponding left or right temporal cortex of surgical resection and overlapped with the clinical resection zones in all patients. The "fall-max" pattern between the phase of low-frequency oscillation and amplitude of high

  18. Flour mill stream blending affects sugar snap cookie and Japanese sponge cake quality and oxidative cross-linking potential of soft white wheat.

    Science.gov (United States)

    The purpose of this research was to study the functional differences between straight grade (75% extraction rate) and patent (60% extraction rate) flour blends from 28 genetically pure soft white and club wheat grain lots, as evidenced by variation in sugar snap cookie and Japanese sponge cake quali...

  19. 75 FR 21050 - V-GPO, Inc., Valesc Holdings, Inc., Venture Stores, Inc., Vertigo Theme Parks, Inc. (f/k/a Snap2...

    Science.gov (United States)

    2010-04-22

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] V-GPO, Inc., Valesc Holdings, Inc., Venture Stores, Inc., Vertigo Theme Parks, Inc. (f/k/a Snap2 Corp.), Videolan Technologies, Inc., VisionGateway... Commission that there is a lack of current and accurate information concerning the securities of Vertigo...

  20. Evaluation of diamide insecticides co-applied with other agrochemicals at various times to manage Ostrinia nubilalis in processing snap bean.

    Science.gov (United States)

    Huseth, Anders S; Groves, Russell L; Chapman, Scott A; Nault, Brian A

    2015-12-01

    Multiple applications of pyrethroid insecticides are used to manage European corn borer, Ostrinia nubilalis Hübner, in snap bean, but new diamide insecticides may reduce application frequency. In a 2 year small-plot study, O. nubilalis control was evaluated by applying cyantraniliprole (diamide) and bifenthrin (pyrethroid) insecticides at one of three phenological stages (bud, bloom and pod formation) of snap bean development. Co-application of these insecticides with either herbicides or fungicides was also examined as a way to reduce the total number of sprays during a season. Cyantraniliprole applications timed either during bloom or during pod formation controlled O. nubilalis better than similar timings of bifenthrin. Co-applications of insecticides with fungicides controlled O. nubilalis as well as insecticide applications alone. Insecticides applied either alone or with herbicides during bud stage did not control this pest. Diamides are an alternative to pyrethroids for the management of O. nubilalis in snap bean. Adoption of diamides by snap bean growers could improve the efficiency of production by reducing the number of sprays required each season. © 2015 Society of Chemical Industry.

  1. Increases in snap bean and soybean seedling diseases associated with a chloride salt and changes in the micro-partitioning of tap root calcium

    Science.gov (United States)

    In a series of field experiments from 1995 through 2010, the incidence of seedling diseases of snap bean and soybean caused by Rhizoctonia solani, Macrophomina phaseolina, Pythium spp., and Fusarium spp. was greater with an application of KCl than with K2SO4 applied at 93 kg K/ha. To determine if th...

  2. EBT Payment for Online Grocery Orders: a Mixed-Methods Study to Understand Its Uptake among SNAP Recipients and the Barriers to and Motivators for Its Use.

    Science.gov (United States)

    Martinez, Olivia; Tagliaferro, Barbara; Rodriguez, Noemi; Athens, Jessica; Abrams, Courtney; Elbel, Brian

    2018-04-01

    To examine Supplemental Nutrition Assistance Program (SNAP) recipients' use of the first online supermarket accepting Electronic Benefit Transfer (EBT) payment. In this mixed-methods study, the authors collected EBT purchase data from an online grocer and attempted a randomized controlled trial in the South Bronx, New York City, followed by focus groups with SNAP beneficiaries aged ≥18 years. Participants were randomized to shop at their usual grocery store or an online supermarket for 3 months. Focus groups explored barriers and motivators to online EBT redemption. Few participants made online purchases, even when incentivized in the randomized controlled trial. Qualitative findings highlighted a lack of perceived control over the online food selection process as a key barrier to purchasing food online. Motivators included fast, free shipping and discounts. Electronic Benefit Transfer for online grocery purchases has the potential to increase food access among SNAP beneficiaries, but challenges exist to this new food buying option. Understanding online food shopping barriers and motivators is critical to the success of policies targeting the online expansion of SNAP benefits. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  3. Examining Internet Access and Social Media Application Use for Online Nutrition Education in SNAP-Ed Participants in Rural Illinois.

    Science.gov (United States)

    Loehmer, Emily; Smith, Sylvia; McCaffrey, Jennifer; Davis, Jeremy

    2018-01-01

    To examine Internet access and interest in receiving nutrition education via social media applications among low-income adults participating in the Supplemental Nutrition Assistance Program Education (SNAP-Ed). A cross-sectional survey was distributed during 25 SNAP-Ed classes throughout the 16 southernmost counties of Illinois. From 188 responses, the majority of participants had Internet access (76%). Among participants aged 18-32 years (n = 51), 92% owned a smartphone with Internet access and 57% indicated that they would use online nutrition education, with most interest in e-mail (41%), Facebook (40%), and text messaging (35%). There was little interest in using blogs, Vine, Twitter, Tumblr, and Pinterest. Overall, 49% of middle-aged adults aged 33-64 years and 87% of seniors aged ≥65 years reported they would not use online nutrition education. Results indicated similar Internet accessibility in southern Illinois among low-income populations compared with national rural rates. Interest in using online nutrition education varied among SNAP-Ed participants according to age. Young adults appeared to be the most captive audience regarding online nutrition education. Results may be useful to agencies implementing SNAP-Ed to supplement current curriculum with online nutrition education for audiences aged ≤32 years. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  4. Preclinical in vitro and in vivo evaluation of [11C]SNAP-7941 – the first PET tracer for the melanin concentrating hormone receptor 1

    International Nuclear Information System (INIS)

    Philippe, Cécile; Nics, Lukas; Zeilinger, Markus; Kuntner, Claudia; Wanek, Thomas; Mairinger, Severin; Shanab, Karem; Spreitzer, Helmut; Viernstein, Helmut; Wadsak, Wolfgang; Mitterhauser, Markus

    2013-01-01

    Introduction: Due to its involvement in a variety of pathologies (obesity, diabetes, gut inflammation and depression), the melanin concentrating hormone receptor 1 (MCHR1) is a new target for the treatment of these lifestyle diseases. We previously presented the radiosynthesis of [ 11 C]SNAP-7941, the first potential PET tracer for the MCHR1. Methods: We herein present its in vitro and in vivo evaluation, including binding affinity, plasma stability, stability against liver mircrosomes and carboxylesterase, lipohilicity, biodistribution, in vivo metabolism and small-animal PET. Results: [ 11 C]SNAP-7941 evinced high stability against liver microsomes, carboxylesterase and in human plasma. The first small-animal PET experiments revealed a 5 fold increased brain uptake after Pgp/BCRP inhibition. Therefore, it can be assumed that [ 11 C]SNAP-7941 is a Pgp/BCRP substrate. No metabolites were found in brain. Conclusion: On the basis of these experiments with healthy rats, the suitability of [ 11 C]SNAP-7941 for the visualisation of central and peripheral MCHR1 remains speculative

  5. The SNAP-25 gene is associated with cognitive ability: evidence from a family-based study in two independent Dutch cohorts

    NARCIS (Netherlands)

    Gosso, M.F.; de Geus, E.J.C.; van Belzen, MJ; Polderman, T.J.C.; Heutink, P.; Boomsma, D.I.; Posthuma, D.

    2006-01-01

    The synaptosomal-associated protein of 25 kDa (SNAP-25) gene plays an integral role in synaptic transmission, and is differentially expressed in the mammalian brain in the neocortex, hippocampus, anterior thalamic nuclei, substantia nigra and cerebellar granular cells. Recent studies have suggested

  6. Double logarithmic asymptotics of quark amplitudes with flavour exchange

    International Nuclear Information System (INIS)

    Kirschner, R.

    1982-01-01

    Results on the quark scattering and annihilation amplitudes in the Regge region are presented. The perturbative contribution to those amplitudes in the double logarithmic approximation are calculated. In the calculations a method based on dispersion relations and gauge invariance is used. (M.F.W.)

  7. Multi-loop string amplitudes and Riemann surfaces

    International Nuclear Information System (INIS)

    Taylor, J.G.

    1986-01-01

    The paper was presented at the workshop on 'Supersymmetry and its applications', Cambridge, United Kingdom, 1985. Super-string theory is discussed under the following topic headings: the functional approach to the string amplitude, Rieman surfaces, the determinants Δsub(epsilon)(1) and Δsub(epsilon)(2), Green's functions, total amplitude, and divergence analysis. (U.K.)

  8. Damping and Frequency Shift of Large Amplitude Electron Plasma Waves

    DEFF Research Database (Denmark)

    Thomsen, Kenneth; Juul Rasmussen, Jens

    1983-01-01

    The initial evolution of large-amplitude one-dimensional electron waves is investigated by applying a numerical simulation. The initial wave damping is found to be strongly enhanced relative to the linear damping and it increases with increasing amplitude. The temporal evolution of the nonlinear...

  9. Singularities of elastic scattering amplitude by long-range potentials

    International Nuclear Information System (INIS)

    Kvitsinsky, A.A.; Komarov, I.V.; Merkuriev, S.P.

    1982-01-01

    The angular peculiarities and the zero energy singularities of the elastic scattering amplitude by a long-range potential are described. The singularities of the elastic (2 → 2) scattering amplitude for a system of three Coulomb particles are considered [ru

  10. Properties of the scattering amplitude for electron-atom collisions

    International Nuclear Information System (INIS)

    Combes, J.M.; Tip, A.

    1983-02-01

    For the scattering of an electron by an atom finiteness of the amplitude at non threshold energies is proved in the framework of the N-body Schroedinger equation. It is also shown that both the direct and exchange amplitudes have analytic continuations for complex values of incident momentum, with pole or cut singularities on the imaginary axis

  11. Miracles in Scattering Amplitudes: from QCD to Gravity

    Energy Technology Data Exchange (ETDEWEB)

    Volovich, Anastasia [Brown Univ., Providence, RI (United States)

    2016-10-09

    The goal of my research project "Miracles in Scattering Amplitudes: from QCD to Gravity" involves deepening our understanding of gauge and gravity theories by exploring hidden structures in scattering amplitudes and using these rich structures as much as possible to aid practical calculations.

  12. Weak decay amplitudes in large N/sub c/ QCD

    International Nuclear Information System (INIS)

    Bardeen, W.A.

    1988-10-01

    A systematic analysis of nonleptonic decay amplitudes is presented using the large N/sub c/ expansion of quantum chromodynamics. In the K-meson system, this analysis is applied to the calculation of the weak decay amplitudes, weak mixing and CP violation. 10 refs., 5 figs., 2 tabs

  13. Abnormal Selective Attention Normalizes P3 Amplitudes in PDD

    Science.gov (United States)

    Hoeksma, Marco R.; Kemner, Chantal; Kenemans, J. Leon; van Engeland, Herman

    2006-01-01

    This paper studied whether abnormal P3 amplitudes in PDD are a corollary of abnormalities in ERP components related to selective attention in visual and auditory tasks. Furthermore, this study sought to clarify possible age differences in such abnormalities. Children with PDD showed smaller P3 amplitudes than controls, but no abnormalities in…

  14. Multiphoton states and amplitude k-th power squeezing

    International Nuclear Information System (INIS)

    Buzek, V.; Jex, I.

    1991-01-01

    On the basis of the work of d'Ariano and coworkers a new type of multiphoton states is introduced. Amplitude k-th power squeezing of the multiphoton states are analysed. In particular, it is shown that even if the multiphoton states do not exhibit ordinary squeezing they can be amplitude k-th power squeezed

  15. Automated force controller for amplitude modulation atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Miyagi, Atsushi, E-mail: atsushi.miyagi@inserm.fr, E-mail: simon.scheuring@inserm.fr; Scheuring, Simon, E-mail: atsushi.miyagi@inserm.fr, E-mail: simon.scheuring@inserm.fr [U1006 INSERM, Université Aix-Marseille, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, 13009 Marseille (France)

    2016-05-15

    Atomic Force Microscopy (AFM) is widely used in physics, chemistry, and biology to analyze the topography of a sample at nanometer resolution. Controlling precisely the force applied by the AFM tip to the sample is a prerequisite for faithful and reproducible imaging. In amplitude modulation (oscillating) mode AFM, the applied force depends on the free and the setpoint amplitudes of the cantilever oscillation. Therefore, for keeping the applied force constant, not only the setpoint amplitude but also the free amplitude must be kept constant. While the AFM user defines the setpoint amplitude, the free amplitude is typically subject to uncontrollable drift, and hence, unfortunately, the real applied force is permanently drifting during an experiment. This is particularly harmful in biological sciences where increased force destroys the soft biological matter. Here, we have developed a strategy and an electronic circuit that analyzes permanently the free amplitude of oscillation and readjusts the excitation to maintain the free amplitude constant. As a consequence, the real applied force is permanently and automatically controlled with picoNewton precision. With this circuit associated to a high-speed AFM, we illustrate the power of the development through imaging over long-duration and at various forces. The development is applicable for all AFMs and will widen the applicability of AFM to a larger range of samples and to a larger range of (non-specialist) users. Furthermore, from controlled force imaging experiments, the interaction strength between biomolecules can be analyzed.

  16. Numerical evaluation of one-loop QCD amplitudes

    DEFF Research Database (Denmark)

    Badger, Simon David; Biedermann, Benedikt; Uwer, Peter

    2012-01-01

    We present the publicly available program NGluon allowing the numerical evaluation of primitive amplitudes at one-loop order in massless QCD. The program allows the computation of one-loop amplitudes for an arbitrary number of gluons. The focus of the present article is the extension to one-loop ...

  17. Conformal higher spin scattering amplitudes from twistor space

    Energy Technology Data Exchange (ETDEWEB)

    Adamo, Tim [Blackett Laboratory, Imperial College, London, SW7 2AZ (United Kingdom); Hähnel, Philipp; McLoughlin, Tristan [School of Mathematics, Trinity College Dublin, College Green, Dublin 2 (Ireland)

    2017-04-04

    We use the formulation of conformal higher spin (CHS) theories in twistor space to study their tree-level scattering amplitudes, finding expressions for all three-point (MHV)-bar amplitudes and all MHV amplitudes involving positive helicity conformal gravity particles and two negative helicity higher spins. This provides the on-shell analogue for the covariant coupling of CHS fields to a conformal gravity background. We discuss the restriction of the theory to a ghost-free unitary subsector, analogous to restricting conformal gravity to general relativity with a cosmological constant. We study the flat-space limit and show that the restricted amplitudes vanish, supporting the conjecture that in the unitary sector the S-matrix of CHS theories is trivial. However, by appropriately rescaling the amplitudes we find non-vanishing results which we compare with chiral flat-space higher spin theories.

  18. Simplicity in the structure of QED and gravity amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Badger, Simon [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Bjerrum-Bohr, N.E.J. [Institute for Advanced Study, Princeton, NJ (United States). School of Natural Sciences; Vanhove, Pierre [Institut des Hautes Etudes Scientifiques IHES, Bures sur Yvette (France); CEA, IPhT, CNRS, URA, Gif-sur-Yvette, (France). Inst. de Physique Theorique

    2008-11-15

    We investigate generic properties of one-loop amplitudes in unordered gauge theories in four dimensions. For such theories the organisation of amplitudes in manifestly crossing symmetric expressions poses restrictions on their structure and results in remarkable cancellations. We show that one-loop multi-photon amplitudes in QED with at least eight external photons are given only by scalar box integral functions. This QED 'no-triangle' property is true for all helicity configurations and has similarities to the 'notriangle' property found in the case of maximal N=8 supergravity. Results are derived both via a world-line formalism as well as using on-shell unitarity methods. We show that the simple structure of the loop amplitude originates from the extremely good BCFW scaling behaviour of the QED tree-amplitude. (orig.)

  19. Simplicity in the structure of QED and gravity amplitudes

    International Nuclear Information System (INIS)

    Badger, Simon; Bjerrum-Bohr, N.E.J.; Vanhove, Pierre; CEA, IPhT, CNRS, URA, Gif-sur-Yvette,

    2008-11-01

    We investigate generic properties of one-loop amplitudes in unordered gauge theories in four dimensions. For such theories the organisation of amplitudes in manifestly crossing symmetric expressions poses restrictions on their structure and results in remarkable cancellations. We show that one-loop multi-photon amplitudes in QED with at least eight external photons are given only by scalar box integral functions. This QED 'no-triangle' property is true for all helicity configurations and has similarities to the 'notriangle' property found in the case of maximal N=8 supergravity. Results are derived both via a world-line formalism as well as using on-shell unitarity methods. We show that the simple structure of the loop amplitude originates from the extremely good BCFW scaling behaviour of the QED tree-amplitude. (orig.)

  20. High Frequency Amplitude Detector for GMI Magnetic Sensors

    Directory of Open Access Journals (Sweden)

    Aktham Asfour

    2014-12-01

    Full Text Available A new concept of a high-frequency amplitude detector and demodulator for Giant-Magneto-Impedance (GMI sensors is presented. This concept combines a half wave rectifier, with outstanding capabilities and high speed, and a feedback approach that ensures the amplitude detection with easily adjustable gain. The developed detector is capable of measuring high-frequency and very low amplitude signals without the use of diode-based active rectifiers or analog multipliers. The performances of this detector are addressed throughout the paper. The full circuitry of the design is given, together with a comprehensive theoretical study of the concept and experimental validation. The detector has been used for the amplitude measurement of both single frequency and pulsed signals and for the demodulation of amplitude-modulated signals. It has also been successfully integrated in a GMI sensor prototype. Magnetic field and electrical current measurements in open- and closed-loop of this sensor have also been conducted.

  1. Conformal higher spin scattering amplitudes from twistor space

    International Nuclear Information System (INIS)

    Adamo, Tim; Hähnel, Philipp; McLoughlin, Tristan

    2017-01-01

    We use the formulation of conformal higher spin (CHS) theories in twistor space to study their tree-level scattering amplitudes, finding expressions for all three-point (MHV)-bar amplitudes and all MHV amplitudes involving positive helicity conformal gravity particles and two negative helicity higher spins. This provides the on-shell analogue for the covariant coupling of CHS fields to a conformal gravity background. We discuss the restriction of the theory to a ghost-free unitary subsector, analogous to restricting conformal gravity to general relativity with a cosmological constant. We study the flat-space limit and show that the restricted amplitudes vanish, supporting the conjecture that in the unitary sector the S-matrix of CHS theories is trivial. However, by appropriately rescaling the amplitudes we find non-vanishing results which we compare with chiral flat-space higher spin theories.

  2. Effects of Thiamethoxam-Treated Seed on Mexican Bean Beetle (Coleoptera: Coccinellidae), Nontarget Arthropods, and Crop Performance in Southwestern Virginia Snap Beans.

    Science.gov (United States)

    Nottingham, L; Kuhar, T P; Kring, T; Herbert, D A; Arancibia, R; Schultz, P

    2017-12-08

    Thiamethoxam is a neonicotinoid insecticide commonly applied directly to the seeds (seed-treatment) of commercial snap beans, Phaseolus vulgaris L. While previous studies have examined target and nontarget effects of thiamethoxam seed-treatments in snap beans and other crops, to our knowledge, none have been conducted in agroecosystems predominated by the pest Mexican bean beetle, Epilachna varivestis Mulsant (Coleoptera: Coccinellidae). This study examined the effects of thiamethoxam-treated snap beans on E. varivestis, other arthropods, and crop performance in southwestern Virginia. Greenhouse experiments were conducted to evaluate residual toxicity of treated snap beans to E. varivestis and a key predator, Podisus maculiventris (Say) (Hemiptera: Pentatomidae). Treated plants were highly toxic to E. varivestis at 13 d, moderately toxic from 16 to 20 d, and minimally toxic at 24 d. P. maculiventris was unaffected by exposure to treated plants or by feeding on E. varivestis that consumed treated plants. Small plot field experiments in 2014 and 2015 showed no significant effects of thiamethoxam seed-treatments on E. varivestis densities, other arthropods, crop injury, or yield. In 2016, planting was delayed by persistent rain, resulting in early E. varivestis colonization. In this year, thiamethoxam-treated plants had significantly lower densities and feeding injury from E. varivestis, followed by significantly higher yields. Natural enemies were unaffected by seed-treatments in all field experiments. These experiments demonstrated that thiamethoxam seed-treatments provide control of E. varivestis when beetles infest fields within 2 to 3 wk after planting; but otherwise provide negligible advantages. Negative effects from thiamethoxam seed-treatments on nontarget arthropods appear minimal for snap beans in this region. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please

  3. Interactions Between SNAP-25 and Synaptotagmin-1 Are Involved in Vesicle Priming, Clamping Spontaneous and Stimulating Evoked Neurotransmission

    DEFF Research Database (Denmark)

    Schupp, Melanie; Malsam, Jörg; Ruiter, Marvin

    2016-01-01

    between region I (vesicle priming) and region II (evoked release). Spontaneous release was disinhibited by region I mutations and found to correlate with defective complexin (Cpx) clamping in an in vitro fusion assay, pointing to an interdependent role of synaptotagmin and Cpx in release clamping...... triggering, depend on direct SNARE complex interaction. SIGNIFICANCE STATEMENT: The function of synaptotagmin-1 (syt-1):soluble NSF attachment protein receptor (SNARE) interactions during neurotransmission remains unclear. We mutated SNAP-25 within the recently identified region I and region II...... was disinhibited by region I mutation and found to correlate with defective complexin (Cpx) clamping in vitro, pointing to an interdependent role of synaptotagmin and Cpx in release clamping. Therefore, vesicle priming, clamping spontaneous release, and eliciting evoked release are three different functions of syt...

  4. Subcellular localization of proteins in the anaerobic sulfate reducer Desulfovibrio vulgaris via SNAP-tag labeling and photoconversion

    Energy Technology Data Exchange (ETDEWEB)

    Gorur, A.; Leung, C. M.; Jorgens, D.; Tauscher, A.; Remis, J. P.; Ball, D. A.; Chhabra, S.; Fok, V.; Geller, J. T.; Singer, M.; Hazen, T. C.; Juba, T.; Elias, D.; Wall, J.; Biggin, M.; Downing, K. H.; Auer, M.

    2010-06-01

    Systems Biology studies the temporal and spatial 3D distribution of macromolecular complexes with the aim that such knowledge will allow more accurate modeling of biological function and will allow mathematical prediction of cellular behavior. However, in order to accomplish accurate modeling precise knowledge of spatial 3D organization and distribution inside cells is necessary. And while a number of macromolecular complexes may be identified by its 3D structure and molecular characteristics alone, the overwhelming number of proteins will need to be localized using a reporter tag. GFP and its derivatives (XFPs) have been traditionally employed for subcelllar localization using photoconversion approaches, but this approach cannot be taken for obligate anaerobic bacteria, where the intolerance towards oxygen prevents XFP approaches. As part of the GTL-funded PCAP project (now ENIGMA) genetic tools have been developed for the anaerobe sulfate reducer Desulfovibrio vulgaris that allow the high-throughput generation of tagged-protein mutant strains, with a focus on the commercially available SNAP-tag cell system (New England Biolabs, Ipswich, MA), which is based on a modified O6-alkylguanine-DNA alkyltransferase (AGT) tag, that has a dead-end reaction with a modified O6-benzylguanine (BG) derivative and has been shown to function under anaerobic conditions. After initial challenges with respect to variability, robustness and specificity of the labeling signal we have optimized the labeling. Over the last year, as a result of the optimized labeling protocol, we now obtain robust labeling of 20 out of 31 SNAP strains. Labeling for 13 strains were confirmed at least five times. We have also successfully performed photoconversion on 5 of these 13 strains, with distinct labeling patterns for different strains. For example, DsrC robustly localizes to the periplasmic portion of the inner membrane, where as a DNA-binding protein localizes to the center of the cell, where the

  5. Nuclear-Mechanical Coupling: Small Amplitude Mechanical Vibrations and High Amplitude Power Oscillations in Nuclear Reactors

    International Nuclear Information System (INIS)

    Suarez Antola, R.

    2008-11-01

    The cores of nuclear reactors, including its structural parts and cooling fluids, are complex mechanical systems able to vibrate in a set of normal modes and frequencies, if suitable perturbed. The cyclic variations in the strain state of the core materials may produce changes in density. Changes in density modify the reactivity. Changes in reactivity modify thermal power. Modifications in thermal power produce variations in temperature fields. Variations in temperature produce variations in strain due to thermal-elastic effects. If the variation of the temperature field is fast enough and if the Doppler Effect and other stabilizing prompt effects in the fuel are weak enough, a fast oscillatory instability could be produced, coupled with mechanical vibrations of small amplitude. A recently constructed, simple mathematical model of nuclear reactor kinetics, that improves the one due to A.S. Thompson, is reviewed. It was constructed in order to study, in a first approximation, the stability of the reactor: a nonlinear nuclear-thermal oscillator (that corresponds to reactor point kinetics with thermal-elastic feedback and with frozen delayed neutron effects) is coupled nonlinearly with a linear mechanical-thermal oscillator (that corresponds to the first normal mode of mechanical vibrations excited by thermo-elastic effects). This mathematical model is studied here from the standpoint of mechanical vibrations. It is shown how, under certain conditions, a suitable mechanical perturbation could elicit fast and growing oscillatory instabilities in the reactor power. Applying the asymptotic method due to Krylov, Bogoliubov and Mitropolsky, analytical formulae that may be used in the calculation of the time varying amplitude and phase of the mechanical oscillations are given, as functions of the mechanical, thermal and nuclear parameters of the reactor. The consequences for the mechanical integrity of the reactor are assessed. Some conditions, mainly, but not exclusively

  6. Embryonic common snapping turtles (Chelydra serpentina) preferentially regulate intracellular tissue pH during acid-base challenges.

    Science.gov (United States)

    Shartau, Ryan B; Crossley, Dane A; Kohl, Zachary F; Brauner, Colin J

    2016-07-01

    The nests of embryonic turtles naturally experience elevated CO2 (hypercarbia), which leads to increased blood PCO2  and a respiratory acidosis, resulting in reduced blood pH [extracellular pH (pHe)]. Some fishes preferentially regulate tissue pH [intracellular pH (pHi)] against changes in pHe; this has been proposed to be associated with exceptional CO2 tolerance and has never been identified in amniotes. As embryonic turtles may be CO2 tolerant based on nesting strategy, we hypothesized that they preferentially regulate pHi, conferring tolerance to severe acute acid-base challenges. This hypothesis was tested by investigating pH regulation in common snapping turtles (Chelydra serpentina) reared in normoxia then exposed to hypercarbia (13 kPa PCO2 ) for 1 h at three developmental ages: 70% and 90% of incubation, and yearlings. Hypercarbia reduced pHe but not pHi, at all developmental ages. At 70% of incubation, pHe was depressed by 0.324 pH units while pHi of brain, white muscle and lung increased; heart, liver and kidney pHi remained unchanged. At 90% of incubation, pHe was depressed by 0.352 pH units but heart pHi increased with no change in pHi of other tissues. Yearlings exhibited a pHe reduction of 0.235 pH units but had no changes in pHi of any tissues. The results indicate common snapping turtles preferentially regulate pHi during development, but the degree of response is reduced throughout development. This is the first time preferential pHi regulation has been identified in an amniote. These findings may provide insight into the evolution of acid-base homeostasis during development of amniotes, and vertebrates in general. © 2016. Published by The Company of Biologists Ltd.

  7. Expression of putative sex-determining genes during the thermosensitive period of gonad development in the snapping turtle, Chelydra serpentina.

    Science.gov (United States)

    Rhen, T; Metzger, K; Schroeder, A; Woodward, R

    2007-01-01

    Modes of sex determination are quite variable in vertebrates. The developmental decision to form a testis or an ovary can be influenced by one gene, several genes, environmental variables, or a combination of these factors. Nevertheless, certain morphogenetic aspects of sex determination appear to be conserved in amniotes. Here we clone fragments of nine candidate sex-determining genes from the snapping turtle Chelydra serpentina, a species with temperature-dependent sex determination (TSD). We then analyze expression of these genes during the thermosensitive period of gonad development. In particular, we compare gene expression profiles in gonads from embryos incubated at a male-producing temperature to those from embryos at a female-producing temperature. Expression of Dmrt1 and Sox9 mRNA increased gradually at the male-producing temperature, but was suppressed at the female-producing temperature. This finding suggests that Dmrt1 and Sox9 play a role in testis development. In contrast, expression of aromatase, androgen receptor (Ar), and Foxl2 mRNA was constant at the male-producing temperature, but increased several-fold in embryos at the female-producing temperature. Aromatase, Ar, and Foxl2 may therefore play a role in ovary development. In addition, there was a small temperature effect on ER alpha expression with lower mRNA levels found in embryos at the female-producing temperature. Finally, Dax1, Fgf9, and SF-1 were not differentially expressed during the sex-determining period, suggesting these genes are not involved in sex determination in the snapping turtle. Comparison of gene expression profiles among amniotes indicates that Dmrt1 and Sox9 are part of a core testis-determining pathway and that Ar, aromatase, ER alpha, and Foxl2 are part of a core ovary-determining pathway. 2007 S. Karger AG, Basel

  8. Phenotypic plasticity in the common snapping turtle (Chelydra serpentina): long-term physiological effects of chronic hypoxia during embryonic development.

    Science.gov (United States)

    Wearing, Oliver H; Eme, John; Rhen, Turk; Crossley, Dane A

    2016-01-15

    Studies of embryonic and hatchling reptiles have revealed marked plasticity in morphology, metabolism, and cardiovascular function following chronic hypoxic incubation. However, the long-term effects of chronic hypoxia have not yet been investigated in these animals. The aim of this study was to determine growth and postprandial O2 consumption (V̇o2), heart rate (fH), and mean arterial pressure (Pm, in kPa) of common snapping turtles (Chelydra serpentina) that were incubated as embryos in chronic hypoxia (10% O2, H10) or normoxia (21% O2, N21). We hypothesized that hypoxic development would modify posthatching body mass, metabolic rate, and cardiovascular physiology in juvenile snapping turtles. Yearling H10 turtles were significantly smaller than yearling N21 turtles, both of which were raised posthatching in normoxic, common garden conditions. Measurement of postprandial cardiovascular parameters and O2 consumption were conducted in size-matched three-year-old H10 and N21 turtles. Both before and 12 h after feeding, H10 turtles had a significantly lower fH compared with N21 turtles. In addition, V̇o2 was significantly elevated in H10 animals compared with N21 animals 12 h after feeding, and peak postprandial V̇o2 occurred earlier in H10 animals. Pm of three-year-old turtles was not affected by feeding or hypoxic embryonic incubation. Our findings demonstrate that physiological impacts of developmental hypoxia on embryonic reptiles continue into juvenile life. Copyright © 2016 the American Physiological Society.

  9. EPINEPHRINE OR GV-26 ELECTRICAL STIMULATION REDUCES INHALANT ANESTHESTIC RECOVERY TIME IN COMMON SNAPPING TURTLES (CHELYDRA SERPENTINA).

    Science.gov (United States)

    Goe, Alexandra; Shmalberg, Justin; Gatson, Bonnie; Bartolini, Pia; Curtiss, Jeff; Wellehan, James F X

    2016-06-01

    Prolonged anesthetic recovery times are a common clinical problem in reptiles following inhalant anesthesia. Diving reptiles have numerous adaptations that allow them to submerge and remain apneic for extended periods. An ability to shunt blood away from pulmonary circulation, possibly due to changes in adrenergic tone, may contribute to their unpredictable inhalant anesthetic recovery times. Therefore, the use of epinephrine could antagonize this response and reduce recovery time. GV-26, an acupuncture point with reported β-adrenergic and respiratory effects, has reduced anesthetic recovery times in other species. In this prospective randomized crossover study, six common snapping turtles (Chelydra serpentina) were anesthetized with inhalant isoflurane for 90 min. Turtles were assigned one of three treatments, given immediately following discontinuation of isoflurane: a control treatment (0.9% saline, at 0.1 ml/kg i.m.), epinephrine (0.1 mg/kg i.m.), or acupuncture with electrical stimulation at GV-26. Each turtle received all treatments, and treatments were separated by 48 hr. Return of spontaneous ventilation was 55% faster in turtles given epinephrine and 58% faster in the GV-26 group versus saline (P < 0.001). The times to movement and to complete recovery were also significantly faster for both treatments than for saline (P < 0.02). Treated turtles displayed increases in temperature not documented in the control (P < 0.001). Turtles administered epinephrine showed significantly increased heart rates and end-tidal CO(2) (P < 0.001). No adverse effects were noted in the study animals. The mechanisms of action were not elucidated in the present investigation. Nevertheless, the use of parenteral epinephrine or GV-26 stimulation in the immediate postanesthetic period produces clinically relevant reductions in anesthetic recovery time in common snapping turtle. Further research is necessary to evaluate the effects of concurrent GV-26 and epinephrine administration

  10. Large amplitude ion-acoustic solitons in dusty plasmas

    International Nuclear Information System (INIS)

    Tiwari, R. S.; Jain, S. L.; Mishra, M. K.

    2011-01-01

    Characteristics of ion-acoustic soliton in dusty plasma, including the dynamics of heavily charged massive dust grains, are investigated following the Sagdeev Potential formalism. Retaining fourth order nonlinearities of electric potential in the expansion of the Sagdeev Potential in the energy equation for a pseudo particle and integrating the resulting energy equation, large amplitude soliton solution is determined. Variation of amplitude (A), half width (W) at half maxima and the product P = AW 2 of the Korteweg-deVries (KdV), dressed and large amplitude soliton as a function of wide range of dust concentration are numerically studied for recently observed parameters of dusty plasmas. We have also presented the region of existence of large amplitude ion-acoustic soliton in the dusty plasma by analyzing the structure of the pseudo potential. It is found that in the presence of positively charged dust grains, system supports only compressive solitons, on the other hand, in the presence of negatively charged dust grains, the system supports compressive solitons up to certain critical concentration of dust grains and above this critical concentration, the system can support rarefactive solitons also. The effects of dust concentration, charge, and mass of the dust grains, on the characteristics of KdV, dressed and large amplitude the soliton, i.e., amplitude (A), half width at half maxima (W), and product of amplitude (A) and half width at half maxima (P = AW 2 ), are discussed in detail

  11. Fringe image analysis based on the amplitude modulation method.

    Science.gov (United States)

    Gai, Shaoyan; Da, Feipeng

    2010-05-10

    A novel phase-analysis method is proposed. To get the fringe order of a fringe image, the amplitude-modulation fringe pattern is carried out, which is combined with the phase-shift method. The primary phase value is obtained by a phase-shift algorithm, and the fringe-order information is encoded in the amplitude-modulation fringe pattern. Different from other methods, the amplitude-modulation fringe identifies the fringe order by the amplitude of the fringe pattern. In an amplitude-modulation fringe pattern, each fringe has its own amplitude; thus, the order information is integrated in one fringe pattern, and the absolute fringe phase can be calculated correctly and quickly with the amplitude-modulation fringe image. The detailed algorithm is given, and the error analysis of this method is also discussed. Experimental results are presented by a full-field shape measurement system where the data has been processed using the proposed algorithm. (c) 2010 Optical Society of America.

  12. Broadband metasurface holograms: toward complete phase and amplitude engineering.

    Science.gov (United States)

    Wang, Qiu; Zhang, Xueqian; Xu, Yuehong; Gu, Jianqiang; Li, Yanfeng; Tian, Zhen; Singh, Ranjan; Zhang, Shuang; Han, Jiaguang; Zhang, Weili

    2016-09-12

    As a revolutionary three-dimensional imaging technique, holography has attracted wide attention for its ability to photographically record a light field. However, traditional phase-only or amplitude-only modulation holograms have limited image quality and resolution to reappear both amplitude and phase information required of the objects. Recent advances in metasurfaces have shown tremendous opportunities for using a planar design of artificial meta-atoms to shape the wave front of light by optimal control of both its phase and amplitude. Inspired by the concept of designer metasurfaces, we demonstrate a novel amplitude-phase modulation hologram with simultaneous five-level amplitude modulation and eight-level phase modulation. Such a design approach seeks to turn the perceived disadvantages of the traditional phase or amplitude holograms, and thus enable enhanced performance in resolution, homogeneity of amplitude distribution, precision, and signal-to-noise ratio. In particular, the unique holographic approach exhibits broadband characteristics. The method introduced here delivers more degrees of freedom, and allows for encoding highly complex information into designer metasurfaces, thus having the potential to drive next-generation technological breakthroughs in holography.

  13. Renormalization Scale-Fixing for Complex Scattering Amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, Stanley J.; /SLAC; Llanes-Estrada, Felipe J.; /Madrid U.

    2005-12-21

    We show how to fix the renormalization scale for hard-scattering exclusive processes such as deeply virtual meson electroproduction by applying the BLM prescription to the imaginary part of the scattering amplitude and employing a fixed-t dispersion relation to obtain the scale-fixed real part. In this way we resolve the ambiguity in BLM renormalization scale-setting for complex scattering amplitudes. We illustrate this by computing the H generalized parton distribution at leading twist in an analytic quark-diquark model for the parton-proton scattering amplitude which can incorporate Regge exchange contributions characteristic of the deep inelastic structure functions.

  14. Calculation and modular properties of multi-loop superstring amplitudes

    International Nuclear Information System (INIS)

    Danilov, G S

    2012-01-01

    Multi-loop superstring amplitude is calculated in the conventional gauge where Grassmann moduli are carried by the 2D gravitino field. Generally, instead of the modular symmetry, the amplitudes hold the symmetry under modular transformations added by relevant transformations of the 2D local supersymmetry. If a number of loops are larger than 3, the integration measures are not modular forms. In this case the expression for the amplitude contains an integral over the bound of the fundamental region of the modular group. (paper)

  15. Amplitude Modulation in the δ Sct star KIC 7106205

    Directory of Open Access Journals (Sweden)

    Bowman Dominic. M.

    2015-01-01

    Full Text Available The δ Sct star KIC 7106205 showed amplitude modulation in a single p mode, whilst all other p and g modes remained stable in amplitude and phase over 1470 d of the Kepler dataset. The data were divided into 30 time bins of equal length and a series of consecutive Fourier transforms was calculated. A fixed frequency, calculated from a least-squares fit of all data, allowed amplitude and phase for every mode in each time bin to be tracked. The missing p mode energy was not transferred to any other visible modes.

  16. Corrections to the large-angle scattering amplitude

    International Nuclear Information System (INIS)

    Goloskokov, S.V.; Kudinov, A.V.; Kuleshov, S.P.

    1979-01-01

    High-energy behaviour of scattering amplitudes is considered within the frames of Logunov-Tavchelidze quasipotential approach. The representation of scattering amplitude of two scalar particles, convenient for the study of its asymptotic properties is given. Obtained are corrections of the main value of scattering amplitude of the first and the second orders in 1/p, where p is the pulse of colliding particles in the system of the inertia centre. An example of the obtained formulas use for a concrete quasipotential is given

  17. Direct Calculation of the Scattering Amplitude Without Partial Wave Analysis

    Science.gov (United States)

    Shertzer, J.; Temkin, A.; Fisher, Richard R. (Technical Monitor)

    2001-01-01

    Two new developments in scattering theory are reported. We show, in a practical way, how one can calculate the full scattering amplitude without invoking a partial wave expansion. First, the integral expression for the scattering amplitude f(theta) is simplified by an analytic integration over the azimuthal angle. Second, the full scattering wavefunction which appears in the integral expression for f(theta) is obtained by solving the Schrodinger equation with the finite element method (FEM). As an example, we calculate electron scattering from the Hartree potential. With minimal computational effort, we obtain accurate and stable results for the scattering amplitude.

  18. Amplitude-to-frequency converter of radioisotope instruments

    International Nuclear Information System (INIS)

    Demchenkov, V.P.; Korobkov, I.N.

    1988-01-01

    An amplitude-to-frequency converter designed for signal processing of radioisotope relay devices is descibed. The basic elements of the converter are a scaling amplifier, an analog-to-digital converter, a code-to-frequency converter, a null-organ, a delay unit and a clock-pulse generator. The designed amplitude-to-frequency converter takes into account a prior information about the signal shape of the energy spectrum. The converter processes input pulses of 0.10 V amplitude and duration more than 2μs. The energy channel number is 64

  19. Gluon cascades and amplitudes in light-front perturbation theory

    International Nuclear Information System (INIS)

    Cruz-Santiago, C.A.; Staśto, A.M.

    2013-01-01

    We construct the gluon wave functions, fragmentation functions and scattering amplitudes within the light-front perturbation theory. Recursion relations on the light-front are constructed for the wave functions and fragmentation functions, which in the latter case are the light-front analogs of the Berends–Giele recursion relations. Using general relations between wave functions and scattering amplitudes it is demonstrated how to obtain the maximally-helicity violating amplitudes, and explicit verification of the results is based on simple examples.

  20. Quantum correlation versus Bell-inequality violation under the amplitude damping channel

    Energy Technology Data Exchange (ETDEWEB)

    Ma, WenChao; Xu, Shuai; Shi, Jiadong; Ye, Liu, E-mail: yeliu@ahu.edu.cn

    2015-11-06

    We investigate the quantum correlations including quantum discord and entanglement under the amplitude damping channel. Our analysis results indicate that although the entanglement of initial state is degraded due to decoherence, the distribution trend of entanglement is not to be affected. Moreover, we find that the survival time for entanglement is much longer than for the Bell inequality violation, i.e., as time goes on the Bell inequality violation of final state may be not satisfied while the final state still remains entangled. Especially, although quantum entanglement and quantum discord all decrease under the amplitude damping channel, quantum discord (QD) is reduced significantly slower than entanglement. Therefore, the quantum discord is more robust against amplitude damping in comparison to entanglement measures. Furthermore, we also find that there are mixed states having quantum discord higher than that for pure states for a given degree of Bell's inequality violation. This means that the manipulation of nonclassical correlations via a pure state can result in a larger loss of quantum discord than that via a mixed state. - Highlights: • Entanglement distribution trend is not be affected by the decoherent. • The survival time for entanglement is much longer than for the Bell inequality violation. • The quantum discord is more robust against amplitude damping in comparison entanglement measures.