WorldWideScience

Sample records for small craft detection

  1. Maritime Interdiction Operations Small Craft Detection

    International Nuclear Information System (INIS)

    Dougan, A.D.; Trombino, D.; Dunlop, W.; Bordetsky, A.

    2010-01-01

    The Naval Postgraduate School has been conducting Tactical Network Topology (TNT) Maritime Interdiction Operations (MIO) experiments with Lawrence Livermore National Laboratory (LLNL) since early in 2005. In this work, we are investigating cutting edge technology to evaluate use of networks, advanced sensors and collaborative technology for globally-supported maritime interdiction operations. Some examples of our research include communications in harsh environments, between moving ships at sea; small boat drive-by radiation detection; network-centric collaboration with global partners; situational awareness; prototype sensors and biometric instruments. Since 2006, we have studied the concept of using a small vessel with fixed radiation sensors to do initial searches for illicit radioactive materials. In our work, we continue to evaluate concepts of operation for small boat monitoring. For example, in San Francisco Bay we established a simulated choke point using two RHIBs. Each RHIB had a large sodium iodide radiation sensor on board, mounted on the side nearest to the passing potential target boats. Once detections were made, notification over the network prompted a chase RHIB also equipped with a radiation sensor to further investigate the potential target. We have also used an unmanned surface vessel (USV) carrying a radiation sensor to perform the initial discovery. The USV was controlled remotely and to drive by boats in different configurations. The potential target vessels were arranged in a line, as a choke point and randomly spaced in the water. Search plans were problematic when weather, waves and drift complicated the ability to stay in one place. A further challenge is to both detect and identify the radioactive materials during the drive-by. Our radiation detection system, ARAM, Adaptable Radiation Area Monitor, is able to detect, alarm and quickly identify plausible radionuclides in real time. We have performed a number of experiments to better

  2. CRAFT

    DEFF Research Database (Denmark)

    Gammelgaard Nielsen, Anders

    2012-01-01

    At the Aarhus School of Architecture, Associate Professor Anders Gammelgaard has erected a solid wood construction, based on traditional craftsmanship. The entire structure is made of heavy oak timber that is joined together using the old techniques of tongue and groove and dowels. The motivation......-air museums, as a performing art in front of an audience. In this article the author discusses the importance of craft and craftsmanship in contemporary architecture in relation to its users....

  3. Standardized Laboratory Test Requirements for Hardening Equipment to Withstand Wave Impact Shock in Small High Speed Craft

    Science.gov (United States)

    2017-02-06

    axes. DRAFT NSWCCD-80-TR-2017/002 8 REFERENCES 1. Du Cane, P., The Planing Performance, Pressures , and Stresses in a High -Speed...Characterization of Individual Wave Slam Acceleration Responses for High Speed Craft, Proceedings of the 29 th American Towing Tank Conference...Methodologies for Small High -Speed Craft Structure, Equipment, Shock Isolation Seats, and Human Performance At-Sea, 10 th Symposium on High

  4. A Probabilistic and Observation Based Methodology to Estimate Small Craft Harbor Vulnerability to Tsunami Events

    Science.gov (United States)

    Keen, A. S.; Lynett, P. J.; Ayca, A.

    2016-12-01

    Because of the damage resulting from the 2010 Chile and 2011 Japanese tele-tsunamis, the tsunami risk to the small craft marinas in California has become an important concern. The talk will outline an assessment tool which can be used to assess the tsunami hazard to small craft harbors. The methodology is based on the demand and structural capacity of the floating dock system, composed of floating docks/fingers and moored vessels. The structural demand is determined using a Monte Carlo methodology. Monte Carlo methodology is a probabilistic computational tool where the governing might be well known, but the independent variables of the input (demand) as well as the resisting structural components (capacity) may not be completely known. The Monte Carlo approach uses a distribution of each variable, and then uses that random variable within the described parameters, to generate a single computation. The process then repeats hundreds or thousands of times. The numerical model "Method of Splitting Tsunamis" (MOST) has been used to determine the inputs for the small craft harbors within California. Hydrodynamic model results of current speed, direction and surface elevation were incorporated via the drag equations to provide the bases of the demand term. To determine the capacities, an inspection program was developed to identify common features of structural components. A total of six harbors have been inspected ranging from Crescent City in Northern California to Oceanside Harbor in Southern California. Results from the inspection program were used to develop component capacity tables which incorporated the basic specifications of each component (e.g. bolt size and configuration) and a reduction factor (which accounts for the component reduction in capacity with age) to estimate in situ capacities. Like the demand term, these capacities are added probabilistically into the model. To date the model has been applied to Santa Cruz Harbor as well as Noyo River. Once

  5. Concerning the Charging of an Exploration Craft on and near a Small Asteroid

    Science.gov (United States)

    Jackson, T. L.; Zimmerman, M. I.; Farrell, W. M.

    2014-01-01

    Introduction: An object immersed in an airless plasma environment will experience a natural process of surface charging in order to acheieve current balance, or zero net electric current to the object. It has been shown in recent computer simulations that the small-body plasma environment is very complex [1], considering effects of photoemission, topography, and formation of a plasma wake. For this work we consider an exploration craft (or astronaut) immersed within a plasma environment near an asteroid, which exhibits widely varying solar wind and photoelectric particle fluxes and continuously evolving illumination conditions. Objective: We aim to determine how an explo-ration craft or astronaut suit accumulates charge while located in the "nightside" asteroid wake where the particle fluxes are reduced, and in the dayside near-surface photoelectron sheath, by combining an object charging model [2] with kinetic simulations of a near-asteroid plasma environment [1]. We consider an astronaut floating near the asteroid while not in contact with the surface, as well as an astronaut moving along the surface using their hands/gloves to crawl along. Results: The modeling results suggest that remediation of triboelectric charge via accumulation of plasma currents is an important factor to consider when designing future NEA mission infrastructure, especially if repeated and frequent contact with the surface is planned. In shadowed regions such as the location shown in Fig. 1a, the plasma currents are so low (and the effective charge-remediation timescale so long, e.g. minutes to hours) that repeated contact with the surface tribocharges the glove in an uncontrollable fashion, as shown for two representative electron temperatures in Fig. 2a. The resulting buildup of significant negative charge would eventually initiate some other "current of last resort" [4] such as transport of positively-charged dust, field-emission from the glove, or significant alteration of

  6. CRAFTING THE MICROWORLD: HOW ROBERT HOOKE CONSTRUCTED KNOWLEDGE ABOUT SMALL THINGS.

    Science.gov (United States)

    Lawson, Ian

    2016-03-20

    This paper investigates the way in which Robert Hooke constructed his microscopical observations. His Micrographia is justifiably famous for its detailed engravings, which communicated Hooke's observations of tiny nature to his readers, but less attention has been paid to how he went about making the observations themselves. In this paper I explore the relationship between the materiality of his instrument and the epistemic images he produced. Behind the pictures lies an array of hidden materials, and the craft knowledge it took to manipulate them. By investigating the often counter-theoretical and conflicting practices of his ingenious microscope use, I demonstrate the way in which Hooke crafted the microworld for his readers, giving insight into how early modern microscopy was understood by its practitioners and audience.

  7. Application of a Spectral Wave Model to Assess Breakwater Configurations at a Small Craft Harbour on Lake Ontario

    Directory of Open Access Journals (Sweden)

    Amelia H. Cooper

    2016-08-01

    Full Text Available A surface wave model using three nested grids is applied to the eastern end of Lake Ontario to investigate wave propagation from an open lake environment to a small craft harbour protected by a breakwater. The Simulating WAves Nearshore (SWAN spectral wave model, coupled with the Delft3D hydrodynamic model, is applied to simulate a series of storms in November, 2013. The model results are compared to observations from two pressure sensors, and used to quantify wave properties around existing and future breakwaters to evaluate the bulk changes to the harbour configuration. Overall, the results indicate that the rubblemound breakwater reduces wave heights in the existing harbour by 63% compared to no breakwater, and that the addition of a surface breakwater extension could reduce wave heights by an additional 54%. Wave height attenuation was found to be highly dependent on the incident wave direction relative to breakwater orientation. The spectral wave model is useful for simulating wave transformation for broad directional spectra in wind-sea conditions over large scales to semi-protected areas such as small craft harbours.

  8. Transformation Craft (T-Craft) Concept Study

    National Research Council Canada - National Science Library

    Marks, Cynthia; Phelps, Chance; Ryan, Justin; Sorensen, Paul

    2007-01-01

    The objective of the Transformation Craft (T-Craft) innovation team was to develop a conceptual craft that addresses the problem of transporting military vehicles at high speed from the Sea Base to troops inland...

  9. Space Craft

    Science.gov (United States)

    Demski, Jennifer

    2009-01-01

    This article discusses how craft innovative architecture is bringing form to the function of 21st-century learning. It describes the construction of New Tech High at Coppell, in Coppell, Texas, which produces an example of how workplace design principles can be coordinated with modern educational goals. The campus was built on the model of New…

  10. Contextualising Craft: Pedagogical Models for Craft Education

    Science.gov (United States)

    Pollanen, Sinikka

    2009-01-01

    Craft education in Finland is, in many aspects, in a state of change. This concerns the independent position of craft as a school subject, the content of the compulsory craft courses containing textiles and technical work, the implementation of the new concept of a holistic craft process in the National Core Curriculum and so on. This bears…

  11. Brane Craft

    Science.gov (United States)

    Janson, Siegfried

    2017-01-01

    A Brane Craft is a membrane spacecraft with solar cells, command and control electronics, communications systems, antennas, propulsion systems, attitude and proximity sensors, and shape control actuators as thin film structures manufactured on 10 micron thick plastic sheets. This revolutionary spacecraft design can have a thickness of tens of microns with a surface area of square meters to maximize area-to-mass ratios for exceptionally low-mass spacecraft. Communications satellites, solar power satellites, solar electric propulsion stages, and solar sails can benefit from Brane Craft design. It also enables new missions that require low-mass spacecraft with exceptionally high delta-V. Active removal of orbital debris from Earth orbit is the target application for this study.

  12. The Use of Shock Isolation mounts in Small High-Speed Craft to Protect Equipment from Wave Slam Effects

    Science.gov (United States)

    2017-07-01

    hardware, but caution is advised because effective solutions will likely only be achieved by experienced shock isolation designers who pursue unique...provide tractable isolation solutions for craft, but caution is advised because effective solutions will likely only be achieved by experienced...very short duration of local vibration oscillations (e.g., nominal 25 to 50 msec or less) rather than rigid body shock pulse durations (e.g., 100

  13. Relationship between human resource ability and market access capacity on business performance. (case study of wood craft micro- and small-scale industries in Gianyar Regency, Bali)

    Science.gov (United States)

    Sukartini, N. W.; Sudarmini, N. M.; Lasmini, N. K.

    2018-01-01

    The aims of this research are to: (1) analyze the influence of Human Resource Ability on market access capacity in Wood Craft Micro and Small Industry; (2) to analyze the effect of market access capacity on business performance; (3) analyze the influence of Human Resources ability on business performance. Data were collected using questionnaires, interviews, observations, and literature studies. The resulting data were analyzed using Struture Equation Modeling (SEM). The results of the analysis show that (1) there is a positive and significant influence of the ability of Human Resources on market access capacity in Wood Craft Micro-and Small-Scale Industries in Gianyar; (2) there is a positive and significant influence of market access capacity on business performance; and (3) there is a positive and significant influence of Human Resource ability on business performance. To improve the ability to access the market and business performance, it is recommended that human resource ability need to be improved through training; government and higher education institutions are expected to play a role in improving the ability of human resources (craftsmen) through provision of training programs

  14. THE INFLUENCE OF IMPLEMENTING THE STRATEGIC POLICY IN CREATING BUSINESS CLIMATE, BUSINESS ENVIRONMENT AND PROVIDING SUPPORT FACILITIES TOWARDS BUSINESS EMPOWERMENT ON SMALL MEDIUM CRAFT ENTERPRISES IN AMBON INDONESIA

    Directory of Open Access Journals (Sweden)

    Josef Papilaya

    2015-04-01

    Full Text Available This study aims at analyzing and explaining whether there was the influence of implementing the strategic policy in creating business climate, business environment and providing support facilities towards empowerment on small and medium enterprises as well as whether there is synchronously influence of implementing the strategic policy in creating business climate, business environment and providing support facilities for business empowerment on small and medium scale enterprises through a survey in the city of Ambon. The results show, that there is a positive and significant effect of implementing the strategic policy in creating business climate to empower small and medium enterprises. There is a positive and significant effect on the business environment toward the empowerment of small and medium enterprises, there is a positive and significant effect of providing support facilities toward the empowerment of small and medium enterprises, and there is a positive and significant simultaneously effect in business climate, business environment and support facilities for business towards the empowerment of small business in Ambon city. Empowerment programs are conducted to maintain a conducive business climate, including: 1. the innovation promotion, 2. enhancing human resources through training development; 3. providing financial support, 4. giving support to the marketing strategy, 5. opening the business partnership. While the supporting facilities granted to small and medium enterprises including: 1. giving the fishing boat for the Fishermen, 2. providing the workshop (machine shop service facilities to small crafts business Enterprises, 3. establish vendors for small enterprises, 4. provide the area for street vendors, 5. provide tents for merchants culinary who work at night. Providing the assistance to encourage the business climate and create conducive business environment.

  15. Small white matter lesion detection in cerebral small vessel disease

    Science.gov (United States)

    Ghafoorian, Mohsen; Karssemeijer, Nico; van Uden, Inge; de Leeuw, Frank E.; Heskes, Tom; Marchiori, Elena; Platel, Bram

    2015-03-01

    Cerebral small vessel disease (SVD) is a common finding on magnetic resonance images of elderly people. White matter lesions (WML) are important markers for not only the small vessel disease, but also neuro-degenerative diseases including multiple sclerosis, Alzheimer's disease and vascular dementia. Volumetric measurements such as the "total lesion load", have been studied and related to these diseases. With respect to SVD we conjecture that small lesions are important, as they have been observed to grow over time and they form the majority of lesions in number. To study these small lesions they need to be annotated, which is a complex and time-consuming task. Existing (semi) automatic methods have been aimed at volumetric measurements and large lesions, and are not suitable for the detection of small lesions. In this research we established a supervised voxel classification CAD system, optimized and trained to exclusively detect small WMLs. To achieve this, several preprocessing steps were taken, which included a robust standardization of subject intensities to reduce inter-subject intensity variability as much as possible. A number of features that were found to be well identifying small lesions were calculated including multimodal intensities, tissue probabilities, several features for accurate location description, a number of second order derivative features as well as multi-scale annular filter for blobness detection. Only small lesions were used to learn the target concept via Adaboost using random forests as its basic classifiers. Finally the results were evaluated using Free-response receiver operating characteristic.

  16. Computer Crafts for Kids.

    Science.gov (United States)

    Kuntz, Margy; Kuntz, Ann

    This work presents a collection of craft projects that can be created by children. Necessary for completion of each craft is an IBM-compatible computer running Windows, "Word for Windows 6.0," with a mouse, a printer, and plain white printer paper. Simple craft supplies, including glue and scissors, also are needed. In each activity the child is…

  17. Learning craft skills. Exploring preschoolers' craft making process

    Directory of Open Access Journals (Sweden)

    Virpi Yliverronen

    2016-06-01

    Full Text Available The aim of this study was to explore a preschooler craft-making process in which 18 preschool novices cut pieces for fabric bags and designed and printed patterns to decorate the bags. Through the task, children were familiarised with a small-scale holistic craft process. The intention was to determine how preschoolers perceived, verbalised and interpreted the craft-making process and how children used bodily expressions when explaining a learned craft skill. The present study relies on the videographic method: two preschool groups’ stamp printing activities were recorded, and each child was interviewed individually. Children’s embodied expressions were particularly in focus in video analysis. The results reveal that all the children were able to sufficiently explain the making phase, however, some children compensated for missing words using bodily and facial expressions and gestures when talking about making. The results showed that children worked logically, and the skill learning phases of perceiving, making, and interpretation were revealed from their learning.

  18. SWOT ANALYSIS MICRO SMALL MEDIUM ENTREPRISE (MSME GEULIS CRAFT UMBRELLA TO SUCCESS IN LOCAL ECONOMIC DEVELOPMENT RESOURCES DISTRICT TASIKMALAYA

    Directory of Open Access Journals (Sweden)

    K. Dianta A. Sebayang

    2012-03-01

    Full Text Available Development of local economic resources, a new trend in the effort to increase the income of the community and the region. Local factors that determine both in terms of natural resources (raw materials and human resources (labor. This paper attempts to present how small and medium enterprises "Kerajinan Payung Geulis" try to improve economic development based on the development of local economic resources in Tasikmalaya. This study aims to illustrate the potential of entrepreneurs that include the competence and commitment of entrepreneurs in small business business, and to illustrate the strength of business / competitive position, business profile and entrepreneur influenced by environmental condition of external and internal environment, seen from the positive and negative side. The research was conducted on umbrella industry of handicraft business in Tasikmalaya. The method used in this research is descriptive analysis by using SWOT analysis. The results show many problems encountered and very complex, such as: low quality of human resources, limited business capital, low access to markets, access to financial institutions / banks are absent, administrative procedures ignorance, sustainability and limited capacity production; Coupled with the business climate is not conducive to the development of SMEs and entrepreneurship.

  19. Small target detection using objectness and saliency

    Science.gov (United States)

    Zhang, Naiwen; Xiao, Yang; Fang, Zhiwen; Yang, Jian; Wang, Li; Li, Tao

    2017-10-01

    We are motived by the need for generic object detection algorithm which achieves high recall for small targets in complex scenes with acceptable computational efficiency. We propose a novel object detection algorithm, which has high localization quality with acceptable computational cost. Firstly, we obtain the objectness map as in BING[1] and use NMS to get the top N points. Then, k-means algorithm is used to cluster them into K classes according to their location. We set the center points of the K classes as seed points. For each seed point, an object potential region is extracted. Finally, a fast salient object detection algorithm[2] is applied to the object potential regions to highlight objectlike pixels, and a series of efficient post-processing operations are proposed to locate the targets. Our method runs at 5 FPS on 1000*1000 images, and significantly outperforms previous methods on small targets in cluttered background.

  20. In Search of Craft

    Science.gov (United States)

    Schwalbe, Michael

    2010-01-01

    In the spring of 2009, this author asked the director of North Carolina State's Crafts Center to help him find people who might be willing to participate in a project about skill. Bill Wallace, an occasional teacher at the Crafts Center, was one of the people recommended to him. Bill Wallace is a man who can look at a tree and instinctively know…

  1. A Consistent Wave Impact Load Model for Studying Structure, Equipment Ruggedness, Shock Isolation Seats, and Human Comfort in Small High Speed Craft

    Science.gov (United States)

    2016-11-01

    Carderock Division for overall management of wave slam phenomenology and craft motion mechanics investigations. During different periods of the...approach to transition this definition to an equivalent static acceleration, Riley and Coats (2012). The first assumption is that the vertical

  2. Implementing digital crafting : developing

    DEFF Research Database (Denmark)

    Tamke, Martin; Ramsgaard Thomsen, Mette

    2010 in the Danish Design Centre in Copenhagen. The exhibition presents 18 designers, architects and people from the crafts that have an innovative take on the future questions of sustainability, new materials and technology. Their products challenge traditional Danish Design and are yet interconnected...... in the countries traits and the way they design. Curated by the Danish Design Centre, The Danish Architectural Centre and the Danish Crafts Organisation groups of three from the different disciplines were identified in 6 scenarios with distinct expression....

  3. The meaning of craft: craft makers' descriptions of craft as an occupation.

    Science.gov (United States)

    Pöllänen, Sinikka

    2013-05-01

    The aim of this study is to examine how craft makers describe the meaning of craft as an activity in relation to their well-being. The study is based on an analysis of the written narratives of 92 textile craft makers aged 16 to 84. Based on the results, the well-being enhancing nature of craft as a meaningful occupation for those interested in crafting is evident. The significance of craft making as an occupation is described by the following three themes: (a) "the meaning and value of crafts", (b) "the feelings experienced during craft activity", and (c) "the holisticity and intentionality of craft-making". As an activity and a metaphor, craft making helped the participants to adjust to life situations. Elements of craft that enhance well-being can be traced to both the artefacts and the sense of achievement gained in producing them. The effects of craft include personal growth, development of physical and cognitive skills, control of one's body, thoughts, and feelings, as well as cultural and social awareness. The results indicate that the participants noticed the significance of craft as an agony- and stress-reducing and mind-calming activity. Holistic craft and ordinary craft played different roles in maintaining well-being.

  4. Automatic Construction by Contour Crafting Technology

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Khorramshahi

    2017-07-01

    Full Text Available Contour Crafting is a novel technology in construction industry based on 3D printing that uses robotics to construct free form building structures by repeatedly laying down layers of material such as concrete. It is actually an approach to scale up automatic fabrication from building small industrial parts to constructing buildings. However, there are little information about contour crafting (CC in current use; present paper aims to describe the operational steps of creating a whole building by the machine reviewing relevant literature. Furthermore, it will represent the advantages of CC usage compared to traditional construction methods, as well as its applicability in construction industry.

  5. Josiah Wedgwood, Manufacturing and Craft

    DEFF Research Database (Denmark)

    Holt, Robin; Popp, Andrew

    2016-01-01

    Craft and industrial manufacture are often seen as dichotomous, with craft being marginalized during the process of industrialization. We want to look beyond this position, searching for craft in places where it has gone unnoticed and where it might have bloomed anew in the interstices created...

  6. The craft of screenwriting

    NARCIS (Netherlands)

    Weijers, G.W.M.

    2014-01-01

    Isn't it ironic? Screenwriting is not something you learn from a book, or a talent that just falls into your lap. Nevertheless, without talent you will never become a great scriptwriter. Above all scriptwriting is a craft that you learn to master by writing, reflecting, and rewriting time after

  7. Computerized flow monitors detect small kicks

    Energy Technology Data Exchange (ETDEWEB)

    McCann, D.; White, D. (Sedco Forex, Paris (FR))

    1992-02-24

    This paper reports on a smart alarm system installed on a number of offshore rigs and one land rig which can detect kicks more quickly than conventional systems. This rapid kick detection improves rig safety because the smaller the detected influx, the easier it is to control the well. The extensive computerized monitoring system helps drilling personnel detect fluid influxes and fluid losses before the changes in flow would normally be apparent.

  8. Integrated Design of Semi-Displacement Patrol Crafts

    National Research Council Canada - National Science Library

    Gillespy, Andrew J

    2008-01-01

    ... of any one change on the entire system. The initial design of smaller patrol craft is especially difficult due to the lack of design tools able to deal with ships of small size operating in the semi-planing region...

  9. Arteriovenous Malformation Detected by Small Bowel Endoscopy

    Directory of Open Access Journals (Sweden)

    Takaaki Fujii

    2014-10-01

    Full Text Available Gastrointestinal bleeding that originates in the small intestine is often difficult to diagnose. When successful diagnosis reveals a lesion that can be localized preoperatively, the laparoscopic approach is an appropriate and beneficial treatment modality for small bowel resection. A 69-year-old man presented with a 6-month history of gastrointestinal bleeding and symptomatic transfusion-dependent anemia. Upper and lower endoscopy were normal. Double-balloon endoscopy established the source of the bleeding as a 0.5-cm polypoid mass appearing as a submucosal tumor with redness and pulsation in the lower ileum, suggesting a vascular lesion. Laparoscopic small bowel resection was successful in removing the mass in the ileum. Histological evaluation of the mass revealed an arteriovenous malformation. Preoperative small bowel endoscopy can be useful for diagnosing the cause and localization of arteriovenous malformation in the small intestine.

  10. Small Surface Target Detection with EO/IR Sensors

    NARCIS (Netherlands)

    Jong, A.N. de; Kemp, R.A.W.

    1998-01-01

    The detection of small surface targets at sea is an increasing requirement for warships. The present sensors on board do not provide the required detection probabilities for these low observable targets like small rubber boats, floating mines, periscopes, people etc. The reason for the low

  11. Craft qualities translated from traditional crafts to smart textile services

    NARCIS (Netherlands)

    Kuusk, K.; Wensveen, S.A.G.; Tomico Plasencia, O.

    2016-01-01

    In this article we suggest craft and craftsmanship as an inspiration to design more sustainable smart textile services. We look into the opportunities that interactive properties and services bring into the textile and garment life cycle. We use traditional crafts as a source of inspiration for the

  12. Crafting digital media

    CERN Document Server

    James, Daniel

    2010-01-01

    Open source software, also known as free software, now offers a creative platform with world-class programs. Just ask the people who have completed high-quality projects or developed popular web 2.0 sites using open source desktop applications. This phenomenon is no longer underground or restricted to techies - there have been more than 61 million downloads of the Audacity audio editor and more than 60 million downloads of the GIMP for Windows photographic tool from SourceForge.net alone. Crafting Digital Media is your foundation course in photographic manipulation, illustration, animation, 3D

  13. A crafting of potentials

    DEFF Research Database (Denmark)

    Kilbourn, Kyle

    In the movement from understanding the past towards creating the future design anthropology, as a discipline, will turn from one with archival qualities to one endowed with potentials for change. One challenge facing design anthropology is how to show relevance for theory generation while also in......-as is complemented by designing for as design anthropologists stage design workshops, span knowledge traditions, and make design moves. Reflecting on my own research process, I trace a few research tools that underline the craft of design anthropology....

  14. Small leak detection requirements for SNR-300 steam generator operation

    International Nuclear Information System (INIS)

    Dumm, K.

    1975-01-01

    The leak detection philosophy of the SNR-300 steam generators is described. Due to operational demands small leaks have already to be detectable at a stage where secondary tube damage has not yet occurred. The requirements on a leak detection instrument are developed and the instrument itself is described. (author)

  15. Small leak detection requirements for SNR-300 steam generator operation

    Energy Technology Data Exchange (ETDEWEB)

    Dumm, K

    1975-07-01

    The leak detection philosophy of the SNR-300 steam generators is described. Due to operational demands small leaks have already to be detectable at a stage where secondary tube damage has not yet occurred. The requirements on a leak detection instrument are developed and the instrument itself is described. (author)

  16. Self-crafting vegetable snacks

    NARCIS (Netherlands)

    Raghoebar, Sanne; Kleef, van Ellen; Vet, de Emely

    2017-01-01

    Purpose: The purpose of this paper is to test whether the IKEA-effect (Norton et al., 2012) – better liking for self-crafted products than for identical products crafted by others – can be exploited to increase liking and consumption of vegetable snacks in children. Design/methodology/approach: A

  17. Small target pre-detection with an attention mechanism

    Science.gov (United States)

    Wang, Yuehuan; Zhang, Tianxu; Wang, Guoyou

    2002-04-01

    We introduce the concept of predetection based on an attention mechanism to improve the efficiency of small-target detection by limiting the image region of detection. According to the characteristics of small-target detection, local contrast is taken as the only feature in predetection and a nonlinear sampling model is adopted to make the predetection adaptive to detect small targets with different area sizes. To simplify the predetection itself and decrease the false alarm probability, neighboring nodes in the sampling grid are used to generate a saliency map, and a short-term memory is adopted to accelerate the `pop-out' of targets. We discuss the fact that the proposed approach is simple enough in computational complexity. In addition, even in a cluttered background, attention can be led to targets in a satisfying few iterations, which ensures that the detection efficiency will not be decreased due to false alarms. Experimental results are presented to demonstrate the applicability of the approach.

  18. 46 CFR 199.201 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft. 199.201 Section 199.201 Shipping COAST... craft. (a) Each survival craft must be approved and equipped as follows: (1) Each lifeboat must be... addition to the survival craft required in paragraph (b)(1) of this section, additional liferafts must be...

  19. Infrared small target detection with kernel Fukunaga Koontz transform

    Science.gov (United States)

    Liu, Rui-ming; Liu, Er-qi; Yang, Jie; Zhang, Tian-hao; Wang, Fang-lin

    2007-09-01

    The Fukunaga-Koontz transform (FKT) has been proposed for many years. It can be used to solve two-pattern classification problems successfully. However, there are few researchers who have definitely extended FKT to kernel FKT (KFKT). In this paper, we first complete this task. Then a method based on KFKT is developed to detect infrared small targets. KFKT is a supervised learning algorithm. How to construct training sets is very important. For automatically detecting targets, the synthetic target images and real background images are used to train KFKT. Because KFKT can represent the higher order statistical properties of images, we expect better detection performance of KFKT than that of FKT. The well-devised experiments verify that KFKT outperforms FKT in detecting infrared small targets.

  20. To craft or not to craft : The relationships between regulatory focus, job crafting and work outcomes

    NARCIS (Netherlands)

    Brenninkmeijer, Veerle; Hekkert-Koning, Marleen

    2015-01-01

    Purpose – The purpose of this paper is to examine relationships between regulatory focus, job crafting, work engagement and perceived employability. Regulatory focus theory distinguishes between promotion-focused individuals, who strive for growth and development, and preventionfocussed individuals,

  1. 32 CFR 700.406 - Naval Vessel Register, classification of naval craft, and status of ships and service craft.

    Science.gov (United States)

    2010-07-01

    ... craft, and status of ships and service craft. 700.406 Section 700.406 National Defense Department of... Register, classification of naval craft, and status of ships and service craft. (a) The Chief of Naval... craft and the designation of status for each ship and service craft. (b) Commissioned vessels and craft...

  2. SQUID sensor application for small metallic particle detection

    International Nuclear Information System (INIS)

    Tanaka, Saburo; Hatsukade, Yoshimi; Ohtani, Takeyoshi; Suzuki, Shuichi

    2009-01-01

    High-Tc superconducting quantum interference device (SQUID) is an ultra-sensitive magnetic sensor. Since the performance of the SQUID is improved and stabilized, now it is ready for application. One strong candidate for application is a detection system of magnetic foreign matters in industrial products or beverages. There is a possibility that ultra-small metallic foreign matter has been accidentally mixed with industrial products such as lithium ion batteries. If this happens, the manufacturer of the product suffers a great loss recalling products. The outer dimension of metallic particles less than 100 μm cannot be detected by an X-ray imaging, which is commonly used for the inspection. Ionization of the material is also a big issue for beverages in the case of the X-ray imaging. Therefore a highly sensitive and safety detection system for small foreign matters is required. We developed detection systems based on high-Tc SQUID with a high-performance magnetic shield. We could successfully measure small iron particles of 100 μm on a belt conveyer and stainless steel balls of 300 μm in water. These detection levels were hard to be achieved by a conventional X-ray detection or other methods

  3. Rapid detection of small oscillation faults via deterministic learning.

    Science.gov (United States)

    Wang, Cong; Chen, Tianrui

    2011-08-01

    Detection of small faults is one of the most important and challenging tasks in the area of fault diagnosis. In this paper, we present an approach for the rapid detection of small oscillation faults based on a recently proposed deterministic learning (DL) theory. The approach consists of two phases: the training phase and the test phase. In the training phase, the system dynamics underlying normal and fault oscillations are locally accurately approximated through DL. The obtained knowledge of system dynamics is stored in constant radial basis function (RBF) networks. In the diagnosis phase, rapid detection is implemented. Specially, a bank of estimators are constructed using the constant RBF neural networks to represent the training normal and fault modes. By comparing the set of estimators with the test monitored system, a set of residuals are generated, and the average L(1) norms of the residuals are taken as the measure of the differences between the dynamics of the monitored system and the dynamics of the training normal mode and oscillation faults. The occurrence of a test oscillation fault can be rapidly detected according to the smallest residual principle. A rigorous analysis of the performance of the detection scheme is also given. The novelty of the paper lies in that the modeling uncertainty and nonlinear fault functions are accurately approximated and then the knowledge is utilized to achieve rapid detection of small oscillation faults. Simulation studies are included to demonstrate the effectiveness of the approach.

  4. 46 CFR 180.204 - Survival craft-vessels operating on coastwise routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on coastwise routes. 180.204 Section 180.204 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL... Craft § 180.204 Survival craft—vessels operating on coastwise routes. (a) Except as allowed by paragraph...

  5. Positron emission tomography of incidentally detected small pulmonary nodules

    DEFF Research Database (Denmark)

    Fischer, B M; Mortensen, J; Dirksen, A

    2004-01-01

    The aim of this study was to assess the value of fluorodeoxyglucose positron emission tomography (FDG PET) imaging of small pulmonary nodules incidentally detected by spiral computed tomography (CT) in a high-risk population. Ten patients (five females, five males, aged 54-72 years) were recruited...

  6. Small hepatocellular carcinomas in chronic liver disease: Detection with SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Kudo, M.; Hirasa, M.; Takakuwa, H.; Ibuki, Y.; Fujimi, K.; Miyamura, M.; Tomita, S.; Komori, H.; Todo, A.; Kitaura, Y.

    1986-06-01

    Single-photon emission computed tomography (SPECT) performed using a rotating gamma camera was compared with ..cap alpha../sub 1/-fetoprotein (AFP) assay, conventional liver scintigraphy, ultrasound (US) imaging, computed tomography (CT), and selective celiac angiography in 40 patients with a total of 50 small hepatocellular carcinomas (HCCs;<5 cm). The detection rates of US and CT were determined on an initial screening study and on a second, more precisely focused study. The detection rate of small HCCs by the various modalities was as follows: AFP, 13%; liver scintigraphy, 36%; SPECT, 72%; initial screening US, 80%; second, more precise US studies, 94%; initial screening CT, 64%; second, more precise CT study, 82%; angiography, 88%. Although SPECT was inferior to the initial screening US examination in detecting HCCs less than 2 cm in size, its sensitivity was identical to that of the initial screening US study for detecting HCCs of 2-5 cm. The combination of SPECT and US was an excellent method for the early detection of HCCs, yielding a detection rate of 94%.

  7. Various imaging methods in the detection of small hepatomas

    International Nuclear Information System (INIS)

    Nakatsuka, Haruki; Kaminou, Toshio; Takemoto, Kazumasa; Takashima, Sumio; Kobayashi, Nobuyuki; Nakamura, Kenji; Onoyama, Yasuto; Kurioka, Naruto

    1985-01-01

    Fifty-one patients with small hepatomas under 5 cm in diameter were studied to compare the detectability of various imaging methods. Positive finding was obtained in 50 % of the patients by scintigraphy, in 74 % by ultrasonography and in 79 % by CT during screening tests. Rate of detection in retrospective analysis, after the site of the tumor had been known, were 73 %, 93 % and 87 % respectively. Rate of detection was 92 % by celiac arteriography and 98 % by selective hepatic arteriography. In 21 patients, who had the tumor under 3 cm, the rate was 32 % for scintigraphy, 74 % for ultrasonography and 65 % for CT during screening, whereas it was 58 %, 84 % and 75 % retrospectively. By celiac arteriography, it was 85 %, and by hepatic arteriography, 95 %. Rate of detection of small hepatomas in screening tests differed remarkably from that in retrospective analysis. No single method of imaging can disclose reliably the presense of small hepatoma, therefore more than one method should be used in screening. (author)

  8. Fungal decay of traditional fishing craft

    Digital Repository Service at National Institute of Oceanography (India)

    Gupta, R.

    The artisanal fishermen land major portion of fish caught in India, employing traditional fishing craft and methods. These craft are built of indigenous wood and undergo rapid biodeterioration causing great economic loss. Soft-rot fungi...

  9. When Does Job Crafting Generalize To Home Crafting

    DEFF Research Database (Denmark)

    Demerouti, Evangelina; De Gieter, Sara; Haun, Verena

    Purpose: Job crafting represents attempts to expand (seeking resources or challenges) or reduce (reducing demands) the scope of the job such that it fits better to one’s preferences. The spillover hypothesis suggests that individuals generalize behaviors at work also to the non-work domain...

  10. Conceptualizing responsible innovation in craft villages in Vietnam

    NARCIS (Netherlands)

    Voeten, J.; de Haan, J.A.C.; Roome, N.; de Groot, G.A.; Nguyen Thi, Huong; van den Hoven, J.; Doorn, N.; Swierstra, T.; Koops, B.-J.; Romijn, H.

    2014-01-01

    Previous research by the authors has explored small-scale innovations in poor craft producers’ clusters in villages in the Red River Delta in northern Vietnam. Although these innovations resulted in value creation and increased incomes, they also often gave rise to negative environmental or social

  11. Optical aptasensors for quantitative detection of small biomolecules: a review.

    Science.gov (United States)

    Feng, Chunjing; Dai, Shuang; Wang, Lei

    2014-09-15

    Aptasensors are aptamer-based biosensors with excellent recognition capability towards a wide range of targets. Specially, there have been ever-growing interests in the development of aptasensors for the detection of small molecules. This phenomenon is contributed to two reasons. On one hand, small biomolecules play an important role in living organisms with many kinds of biological function, such as antiarrhythmic effect and vasodilator activity of adenosine. On the other hand, the concentration of small molecules can be an indicator for disease diagnosis, for example, the concentration of ATP is closely associated with cell injury and cell viability. As a potential analysis tool in the construction of aptasensors, optical analysis has attracted much more interest of researchers due to its high sensitivity, quick response and simple operation. Besides, it promises the promotion of aptasensors in performance toward a new level. Review the development of optical aptasensors for small biomolecules will give readers an overall understanding of its progress and provide some theoretical guidelines for its future development. Hence, we give a mini-review on the advance of optical aptasensors for small biomolecules. This review focuses on recent achievements in the design of various optical aptasensors for small biomolecules, containing fluorescence aptasensors, colorimetric aptasensors, chemiluminescence aptasensors and other optical aptasensors. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. The SNR-300 steam generator small leak detection system

    International Nuclear Information System (INIS)

    Dumm, K.

    1984-01-01

    Small leak detection in the SNR-300 steam generator moduls is achieved by hydrogen meters. Development and design of the Nickel membrane - ion getter pump combination are described and sensitivity requests derived. Results of calibration tests by water/steam injections in a sodium loop are presented. The arrangement and interconnection of signals in SNR-300 are given and possibilities for inservice calibrations are discussed, supported by long time operation tests in the KNK-reactor plant. (author)

  13. Small Craft Facility Areas - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  14. Small Craft Facility Locations - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  15. Feature-fused SSD: fast detection for small objects

    Science.gov (United States)

    Cao, Guimei; Xie, Xuemei; Yang, Wenzhe; Liao, Quan; Shi, Guangming; Wu, Jinjian

    2018-04-01

    Small objects detection is a challenging task in computer vision due to its limited resolution and information. In order to solve this problem, the majority of existing methods sacrifice speed for improvement in accuracy. In this paper, we aim to detect small objects at a fast speed, using the best object detector Single Shot Multibox Detector (SSD) with respect to accuracy-vs-speed trade-off as base architecture. We propose a multi-level feature fusion method for introducing contextual information in SSD, in order to improve the accuracy for small objects. In detailed fusion operation, we design two feature fusion modules, concatenation module and element-sum module, different in the way of adding contextual information. Experimental results show that these two fusion modules obtain higher mAP on PASCAL VOC2007 than baseline SSD by 1.6 and 1.7 points respectively, especially with 2-3 points improvement on some small objects categories. The testing speed of them is 43 and 40 FPS respectively, superior to the state of the art Deconvolutional single shot detector (DSSD) by 29.4 and 26.4 FPS.

  16. 46 CFR 199.261 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft. 199.261 Section 199.261 Shipping COAST... SYSTEMS FOR CERTAIN INSPECTED VESSELS Additional Requirements for Cargo Vessels § 199.261 Survival craft. (a) Each survival craft must be approved and equipped as follows: (1) Each lifeboat must be a totally...

  17. 46 CFR 28.120 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Survival craft. 28.120 Section 28.120 Shipping COAST... VESSELS Requirements for All Vessels § 28.120 Survival craft. (a) Except as provided in paragraphs (b) through (h) of this section and 28.305, each vessel must carry the survival craft specified in Table 28...

  18. 46 CFR 133.105 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft. 133.105 Section 133.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.105 Survival craft. (a) Each survival craft must be approved and equipped as...

  19. Secondary School Design: Workshop Crafts.

    Science.gov (United States)

    Department of Education and Science, London (England).

    Design features are described for school shop facilities. Some general requirements common to most workshops are discussed; and specific design information is provided for general woodwork, general metalwork, and combined wood and metalwork facilities. The grouping of the workshop crafts and their relation to other parts of the school are also…

  20. Large Scale Community Detection Using a Small World Model

    Directory of Open Access Journals (Sweden)

    Ranjan Kumar Behera

    2017-11-01

    Full Text Available In a social network, small or large communities within the network play a major role in deciding the functionalities of the network. Despite of diverse definitions, communities in the network may be defined as the group of nodes that are more densely connected as compared to nodes outside the group. Revealing such hidden communities is one of the challenging research problems. A real world social network follows small world phenomena, which indicates that any two social entities can be reachable in a small number of steps. In this paper, nodes are mapped into communities based on the random walk in the network. However, uncovering communities in large-scale networks is a challenging task due to its unprecedented growth in the size of social networks. A good number of community detection algorithms based on random walk exist in literature. In addition, when large-scale social networks are being considered, these algorithms are observed to take considerably longer time. In this work, with an objective to improve the efficiency of algorithms, parallel programming framework like Map-Reduce has been considered for uncovering the hidden communities in social network. The proposed approach has been compared with some standard existing community detection algorithms for both synthetic and real-world datasets in order to examine its performance, and it is observed that the proposed algorithm is more efficient than the existing ones.

  1. Acoustic detection for small-leak sodium-water reaction

    International Nuclear Information System (INIS)

    Nei, Hiromichi; Ohshima, Iwao; Ujihara, Kozaburo; Hori, Masao

    1977-01-01

    Characteristics of acoustic signal produced by sodium-water reaction due to steam injection and by Ar gas injection into sodium were experimentally investigated. Acoustic signal was measured by using Kistler 808A and 815A5 accelerometers. Root mean square (RMS) measurements and frequency analysis of the signal were conducted. The RMS measurements could detect a small water leakage into sodium, as small as 0.07g/sec, in the present loop. The peaks in a frequency spectrum were caused by the natural vibration of a rod on which the acoustic transducer was mounted. The RMS was approximately proportional to the one-third power of the steam leak rate and increased to some extent with the ambient sodium temperature. RMS values, both for sodium-water reaction and Ar gas injection, were about the same order of magnitude, when the data were plotted against the volumetric flow rates of steam and Argas. (auth.)

  2. Detecting and identifying small molecules in a nanopore flux capacitor

    International Nuclear Information System (INIS)

    Bearden, Samuel; Zhang, Guigen; McClure, Ethan

    2016-01-01

    A new method of molecular detection in a metallic-semiconductor nanopore was developed and evaluated with experimental and computational methods. Measurements were made of the charging potential of the electrical double layer (EDL) capacitance as charge-carrying small molecules translocated the nanopore. Signals in the charging potential were found to be correlated to the physical properties of analyte molecules. From the measured signals, we were able to distinguish molecules with different valence charge or similar valence charge but different size. The relative magnitude of the signals from different analytes was consistent over a wide range of experimental conditions, suggesting that the detected signals are likely due to single molecules. Computational modeling of the nanopore system indicated that the double layer potential signal may be described in terms of disruption of the EDL structure due to the size and charge of the analyte molecule, in agreement with Huckel and Debye’s analysis of the electrical atmosphere of electrolyte solutions. (paper)

  3. Digital tripwire: a small automated human detection system

    Science.gov (United States)

    Fischer, Amber D.; Redd, Emmett; Younger, A. Steven

    2009-05-01

    A low cost, lightweight, easily deployable imaging sensor that can dependably discriminate threats from other activities within its field of view and, only then, alert the distant duty officer by transmitting a visual confirmation of the threat would provide a valuable asset to modern defense. At present, current solutions suffer from a multitude of deficiencies - size, cost, power endurance, but most notably, an inability to assess an image and conclude that it contains a threat. The human attention span cannot maintain critical surveillance over banks of displays constantly conveying such images from the field. DigitalTripwire is a small, self-contained, automated human-detection system capable of running for 1-5 days on two AA batteries. To achieve such long endurance, the DigitalTripwire system utilizes an FPGA designed with sleep functionality. The system uses robust vision algorithms, such as a partially unsupervised innovative backgroundmodeling algorithm, which employ several data reduction strategies to operate in real-time, and achieve high detection rates. When it detects human activity, either mounted or dismounted, it sends an alert including images to notify the command center. In this paper, we describe the hardware and software design of the DigitalTripwire system. In addition, we provide detection and false alarm rates across several challenging data sets demonstrating the performance of the vision algorithms in autonomously analyzing the video stream and classifying moving objects into four primary categories - dismounted human, vehicle, non-human, or unknown. Performance results across several challenging data sets are provided.

  4. Automated Detection of Small Bodies by Space Based Observation

    Science.gov (United States)

    Bidstrup, P. R.; Grillmayer, G.; Andersen, A. C.; Haack, H.; Jorgensen, J. L.

    The number of known comets and asteroids is increasing every year. Up till now this number is including approximately 250,000 of the largest minor planets, as they are usually referred. These discoveries are due to the Earth-based observation which has intensified over the previous decades. Additionally larger telescopes and arrays of telescopes are being used for exploring our Solar System. It is believed that all near- Earth and Main-Belt asteroids of diameters above 10 to 30 km have been discovered, leaving these groups of objects as observationally complete. However, the cataloguing of smaller bodies is incomplete as only a very small fraction of the expected number has been discovered. It is estimated that approximately 1010 main belt asteroids in the size range 1 m to 1 km are too faint to be observed using Earth-based telescopes. In order to observe these small bodies, space-based search must be initiated to remove atmospheric disturbances and to minimize the distance to the asteroids and thereby minimising the requirement for long camera integration times. A new method of space-based detection of moving non-stellar objects is currently being developed utilising the Advanced Stellar Compass (ASC) built for spacecraft attitude determination by Ørsted, Danish Technical University. The ASC serves as a backbone technology in the project as it is capable of fully automated distinction of known and unknown celestial objects. By only processing objects of particular interest, i.e. moving objects, it will be possible to discover small bodies with a minimum of ground control, with the ultimate ambition of a fully automated space search probe. Currently, the ASC is being mounted on the Flying Laptop satellite of the Institute of Space Systems, Universität Stuttgart. It will, after a launch into a low Earth polar orbit in 2008, test the detection method with the ASC equipment that already had significant in-flight experience. A future use of the ASC based automated

  5. Small Vocabulary with Saliency Matching for Video Copy Detection

    DEFF Research Database (Denmark)

    Ren, Huamin; Moeslund, Thomas B.; Tang, Sheng

    2013-01-01

    The importance of copy detection has led to a substantial amount of research in recent years, among which Bag of visual Words (BoW) plays an important role due to its ability to effectively handling occlusion and some minor transformations. One crucial issue in BoW approaches is the size of vocab......The importance of copy detection has led to a substantial amount of research in recent years, among which Bag of visual Words (BoW) plays an important role due to its ability to effectively handling occlusion and some minor transformations. One crucial issue in BoW approaches is the size...... matching algorithm based on salient visual words selection. More specifically, the variation of visual words across a given video are represented as trajectories and those containing locally asymptotically stable points are selected as salient visual words. Then we attempt to measure the similarity of two...... videos through saliency matching merely based on the selected salient visual words to remove false positives. Our experiments show that a small codebook with saliency matching is quite competitive in video copy detection. With the incorporation of the proposed saliency matching, the precision can...

  6. Detection of small conformational changes of proteins by small-angle scattering

    International Nuclear Information System (INIS)

    Durchschlag, H.; Purr, G.; Zipper, P.; Wilfing, R.

    1991-01-01

    In the past the technique of small-angle scattering has been a powerful tool for studying conformational changes of protein which occur, for example, upon binding with ligands. Results obtained by different authors from X-ray and neutron experiments on a variety of proteins and under various conditions have been compiled. This offers the possibility of comparing the extent of changes in the molecular parameters investigated (e.g. change of the radius of gyration). Problems encountered with the detection of small changes are discussed. As an example, conformational changes of the enzyme citrate synthase upon substrate binding (oxaloacetate) are presented. X-ray crystallography had already found distinct changes between open and closed forms of the enzyme. Small-angle X-ray scattering studies registered slight changes of some parameters in solution. These changes could be paralleled with the results of other solution techniques (UV absorption, fluorescence and circular dichroism spectroscopy, analytical ultracentrifugation). The results found for citrate synthase are also compared with previous findings for malate synthase, an enzyme of similar enzymatic function. Above all, this study shows that care has to be taken when studying small conformational changes. It is absolutely necessary to use different methods and conditions and to study the problem from different points of view to avoid pitfalls. (orig.)

  7. 46 CFR 117.200 - Survival craft-general.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-general. 117.200 Section 117.200 Shipping... Number and Type of Survival Craft § 117.200 Survival craft—general. (a) Each survival craft required on a... craft they replace. (c) A summary of survival craft requirements is provided in Table 117.200(c). Table...

  8. Supporting Craft Sense in Early Education

    Directory of Open Access Journals (Sweden)

    Kalle Virta

    2013-10-01

    Full Text Available The research task was to describe and construct theoretical background for Craft Sense in early education. Craft Sense represents a learner’s skill for obtaining Sloyd (Craft, Design & Technology related knowledge, skills and understanding. The development of Craft Sense is based on producing artefacts and evaluating the production process. In this research, the concept of Craft Sense is based on the integration of Sloyd and meta-cognitive regulation of learning activities. Based on theoretical information, an empirical research question was formulated: “What kind of Craft Sense do children have in early education Sloyd?” The method of study was assessing picture supported learning on a Sloyd course for young children. The data was analyzed by qualitative content analysis and Child Behaviour Rating Scale (CBRS. Findings indicate that the development of children’s Craft Sense can be supported with pictures. Furthermore, the CBRS can be used to evaluate and understand children’s Craft Sense. Keywords: Craft Sense, Sloyd, Sloyd Education, Meta-cognition

  9. Research 2009-2011 - Digital Crafting

    DEFF Research Database (Denmark)

    Ramsgaard Thomsen, Mette; Tamke, Martin; Peder Pedersen, Claus

    2012-01-01

    The publication reports on the international research network 'Digital Crafting' organised in the period 2009-2011. The research network investigated profound changes in the design and building of architecture. Developing the term Digital Crafting, the network examined how the maturing of interfa......The publication reports on the international research network 'Digital Crafting' organised in the period 2009-2011. The research network investigated profound changes in the design and building of architecture. Developing the term Digital Crafting, the network examined how the maturing...

  10. Crafting our energy future

    International Nuclear Information System (INIS)

    van Schagen, Frank

    2005-01-01

    The new Asia-Pacific Greenhouse Agreement offers Australia a great opportunity to take full advantage of both its brains and its energy resources. The energy debate is often, simplistically, characterised as coal versus nuclear, or non-renewables versus renewables. In reality we will need a mix of energy sources to power our economy, cleanly, into the future. The issues are cost, environmental protection, national security, skills and security of energy supply. If we wish our economy to continue growing at present rates, we will need 50 per cent more energy in 2030 than we use today - and it is not too soon to start planning how we will produce it. We have around 500 years' supply of coal resources at present rates of usage. Power generation from coal is capable of achieving zero, or near zero, carbon emissions using technologies such as oxy-fuel combustion or IGCC (integrated gasification combined cycle). In both, C0 2 can be captured and stored underground. The greenhouse debate has revived interest in nuclear power generation. The cost of generating electricity with nuclear is similar to clean coal. However, we would have to start a nuclear power industry from a very small base, buying costly generation plant and training or importing an entire, highly-skilled workforce, in competition with other countries. Waste disposal is an issue for both coal and nuclear. For coal, the main option is carbon capture and its storage in deep saline aquifers. This technology is well understood and widely used by the oil and gas industry but we have to determine the most suitable places and techniques, and we have to build the infrastructure. Nuclear waste storage is also well-understood. Which technology we choose depends on an evaluation of both short and long term risks for the community and environment. One thing that Australia must get right is the economics. The wrong decision will cost us jobs, if not entire industries and regions. While renewables like solar and wind are

  11. The craft of scientific writing

    CERN Document Server

    Alley, Michael

    2019-01-01

    The Craft of Scientific Writing uses scores of examples to show the differences between scientific writing that informs and persuades and scientific writing that does not. Focusing on technical papers, dissertations, and reports, this text shows engineers, scientists, and technical professionals the five keys of style that distinguish the best scientific documents: (1) having the details presented in a methodical fashion, (2) having the important details emphasized, (3) having ideas cast into clear and precise sentences, (4) having clear connections between those ideas, and (5) having illustrations that persuade.

  12. Crafting in context: Exploring when job crafting is dysfunctional for performance effectiveness.

    Science.gov (United States)

    Dierdorff, Erich C; Jensen, Jaclyn M

    2018-05-01

    Job crafting theory purports that the consequences of revising one's work role can be simultaneously beneficial and detrimental. Previous research, however, has almost exclusively emphasized the beneficial outcomes of job crafting. In the current study, we proposed dysfunctional consequences of crafting for performance-related outcomes in the form of a U-shaped relationship between job crafting and performance effectiveness (managerial ratings of job proficiency and peer ratings of citizenship behavior). We further predicted that elements of the task context (autonomy and ambiguity) and the social context (interdependence and social support) moderate these curvilinear relationships. Consistent with previous research, job crafting displayed positive and linear effects on work-related attitudes (job satisfaction and affective commitment). Consistent with our predictions, moderate levels of crafting were associated with dysfunctional performance-related outcomes and features of work context either exacerbated or dissipated these dysfunctional consequences of job crafting for individuals. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  13. Crafting forgiveness accounts after war

    DEFF Research Database (Denmark)

    Meinert, Lotte; Obika, Julaina; Whyte, Susan Reynolds

    2014-01-01

    artist, the authors collected personal voice accounts of these ‘social repair’ processes and audio edited them in order to share them with a local public. The editing process raised critical issues regarding ‘editing for effect’, which are of wider relevance for discussions of ethnographic representation...... and social processes of editing past experience. As a way of crafting and controlling material, editing is always ‘for effect’. But the authors were struck by the powerful potentials of this artistic editing and by the difficulty in foreseeing or controlling its consequences among listeners. They suggest...... that personal processes of forgiveness resemble processes of editing, in the sense that past experience is revised and given narrative form, with an effect on the present and future of social relationships. When we edit, we foreground and background segments of data and experience, and cut parts of our...

  14. 46 CFR 117.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 117.130 Section 117.130... AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 117.130 Stowage of survival craft. (a) Each survival craft must be: (1) Secured to the vessel by a painter with a float-free link permanently...

  15. 46 CFR 133.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 133.130 Section 133.130... SYSTEMS Requirements for All OSVs § 133.130 Stowage of survival craft. (a) General. Each survival craft must be stowed as follows: (1) Each survival craft must be as close to the accommodation and service...

  16. 46 CFR 180.175 - Survival craft equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft equipment. 180.175 Section 180.175... TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 180.175 Survival craft equipment. (a) General. Each item of survival craft equipment must be of good quality, and...

  17. 46 CFR 199.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 199.130 Section 199.130... craft. (a) General. Each survival craft must be stowed— (1) As close to the accommodation and service spaces as possible; (2) So that neither the survival craft nor its stowage arrangements will interfere...

  18. 46 CFR 117.175 - Survival craft equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft equipment. 117.175 Section 117.175... AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 117.175 Survival craft equipment. (a) General. Each item of survival craft equipment must be of good quality, and efficient for the purpose it...

  19. 46 CFR 117.150 - Survival craft embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft embarkation arrangements. 117.150 Section... EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 117.150 Survival craft embarkation... apparatus when either— (1) The embarkation station for the survival craft is on a deck more than 4.5 meters...

  20. 46 CFR 180.130 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 180.130 Section 180.130... TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 180.130 Stowage of survival craft. (a) Each survival craft must be: (1) Secured to the vessel by a painter with a...

  1. 46 CFR 28.310 - Launching of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Launching of survival craft. 28.310 Section 28.310... Operate With More Than 16 Individuals on Board § 28.310 Launching of survival craft. A gate or other... each survival craft which weighs more than 110 pounds (489 Newtons), to allow the survival craft to be...

  2. Detection algorithm of infrared small target based on improved SUSAN operator

    Science.gov (United States)

    Liu, Xingmiao; Wang, Shicheng; Zhao, Jing

    2010-10-01

    The methods of detecting small moving targets in infrared image sequences that contain moving nuisance objects and background noise is analyzed in this paper. A novel infrared small target detection algorithm based on improved SUSAN operator is put forward. The algorithm selects double templates for the infrared small target detection: one size is greater than the small target point size and another size is equal to the small target point size. First, the algorithm uses the big template to calculate the USAN of each pixel in the image and detect the small target, the edge of the image and isolated noise pixels; Then the algorithm uses the another template to calculate the USAN of pixels detected in the first step and improves the principles of SUSAN algorithm based on the characteristics of the small target so that the algorithm can only detect small targets and don't sensitive to the edge pixels of the image and isolated noise pixels. So the interference of the edge of the image and isolate noise points are removed and the candidate target points can be identified; At last, the target is detected by utilizing the continuity and consistency of target movement. The experimental results indicate that the improved SUSAN detection algorithm can quickly and effectively detect the infrared small targets.

  3. Small-size pedestrian detection in large scene based on fast R-CNN

    Science.gov (United States)

    Wang, Shengke; Yang, Na; Duan, Lianghua; Liu, Lu; Dong, Junyu

    2018-04-01

    Pedestrian detection is a canonical sub-problem of object detection with high demand during recent years. Although recent deep learning object detectors such as Fast/Faster R-CNN have shown excellent performance for general object detection, they have limited success for small size pedestrian detection in large-view scene. We study that the insufficient resolution of feature maps lead to the unsatisfactory accuracy when handling small instances. In this paper, we investigate issues involving Fast R-CNN for pedestrian detection. Driven by the observations, we propose a very simple but effective baseline for pedestrian detection based on Fast R-CNN, employing the DPM detector to generate proposals for accuracy, and training a fast R-CNN style network to jointly optimize small size pedestrian detection with skip connection concatenating feature from different layers to solving coarseness of feature maps. And the accuracy is improved in our research for small size pedestrian detection in the real large scene.

  4. DEVELOPMENT OF INTERACTIVE MULTIMEDIA COURSEWARE (E-CRAFT FOR CRAFT EDUCATION

    Directory of Open Access Journals (Sweden)

    Salyani OSMAN,

    2012-08-01

    Full Text Available The way of teaching and learning traditional crafts have always used traditional apprenticeship learning methods where the expert facilitates transfer of practice skill sets to novices. As a craft has been taught in conventional approach, the students and experts have been facing several problems especially when expert needs to teach a group of students. An appropriate mapping of craft education and Information and Communication Technologies using Multimedia technology for instance, has the potential in transforming traditional craft learning into more flexible environment. This paper reports on a research project on development of an interactive multimedia courseware package for teaching and learning traditional craft called e-CRAFT. The e-CRAFT is specially designed for songket weaving course taught to certificate and diploma students from Fakulti Seni Kraf Tenunan in their first year study at Institut Kraf Negara, Malaysia (National Craft Institute. The courseware was developed in a web-based environment and overall development process was based on the Dick and Carey's process model and conceptual Instructional Design framework. It is made up of eight learning modules: Introduction, Materials & Tools, Knowing Motifs, Learn How to Weave, Quizzes & Test, Online Discussion, Glossary and Help module. In order to test whether the courseware is suitable in terms of usability, pilot testing was done to a sample of 10 students. The results from pilot test received positive feedback which signifies the courseware is considered acceptable for effectiveness study and help for further improve of the e-CRAFT courseware.

  5. Infrared small target detection technology based on OpenCV

    Science.gov (United States)

    Liu, Lei; Huang, Zhijian

    2013-09-01

    Accurate and fast detection of infrared (IR) dim target has very important meaning for infrared precise guidance, early warning, video surveillance, etc. In this paper, some basic principles and the implementing flow charts of a series of algorithms for target detection are described. These algorithms are traditional two-frame difference method, improved three-frame difference method, background estimate and frame difference fusion method, and building background with neighborhood mean method. On the foundation of above works, an infrared target detection software platform which is developed by OpenCV and MFC is introduced. Three kinds of tracking algorithms are integrated in this software. In order to explain the software clearly, the framework and the function are described in this paper. At last, the experiments are performed for some real-life IR images. The whole algorithm implementing processes and results are analyzed, and those algorithms for detection targets are evaluated from the two aspects of subjective and objective. The results prove that the proposed method has satisfying detection effectiveness and robustness. Meanwhile, it has high detection efficiency and can be used for real-time detection.

  6. Modern electrical installation for craft students

    CERN Document Server

    Scaddan, Brian

    2013-01-01

    Modern Electrical Installation for Craft Students, Volume 2, Third Edition discusses several topics concerning electrical installations. The book is comprised of eight chapters that deal with craft theory, associated subjects, and electrical industries. Chapter 1 covers inductors and inductance, while Chapter 2 tackles capacitors and capacitance. Chapter 3 deals with inductance and capacitance in installation work. The book also discusses cells, batteries, and transformers. The electrical industries, control and earthing, and testing are also dealt with. The last chapter discusses the basic el

  7. Employees’ Perceived Opportunities to Craft and In-Role Performance: The Mediating Role of Job Crafting and Work Engagement

    Science.gov (United States)

    van Wingerden, Jessica; Poell, Rob F.

    2017-01-01

    The present study was designed to gain knowledge of the relationship between employees’ perceived opportunities to craft, their actual job crafting behavior and, in line with JD-R theory, subsequently their work engagement and performance. Although scholars have suggested that employees’ perceived opportunities to craft their job may predict their actual job crafting behavior, which may have consequences for their well-being and performance, no study has examined the relationships between these variables. We collected data among a heterogeneous group of Dutch employees (N = 2090). Participants of the study reported their perceived opportunities to craft, job crafting behavior, work engagement and performance. Results indicated that individuals who experience a high level of opportunities to craft reported higher levels of job crafting behavior. In turn, perceived opportunities to craft and job crafting behavior related to higher levels of work engagement and subsequently performance. We discuss the implications of these findings for theory and practice. PMID:29118729

  8. Employees' Perceived Opportunities to Craft and In-Role Performance: The Mediating Role of Job Crafting and Work Engagement.

    Science.gov (United States)

    van Wingerden, Jessica; Poell, Rob F

    2017-01-01

    The present study was designed to gain knowledge of the relationship between employees' perceived opportunities to craft, their actual job crafting behavior and, in line with JD-R theory, subsequently their work engagement and performance. Although scholars have suggested that employees' perceived opportunities to craft their job may predict their actual job crafting behavior, which may have consequences for their well-being and performance, no study has examined the relationships between these variables. We collected data among a heterogeneous group of Dutch employees ( N = 2090). Participants of the study reported their perceived opportunities to craft, job crafting behavior, work engagement and performance. Results indicated that individuals who experience a high level of opportunities to craft reported higher levels of job crafting behavior. In turn, perceived opportunities to craft and job crafting behavior related to higher levels of work engagement and subsequently performance. We discuss the implications of these findings for theory and practice.

  9. Eddy Current Testing for Detecting Small Defects in Thin Films

    Science.gov (United States)

    Obeid, Simon; Tranjan, Farid M.; Dogaru, Teodor

    2007-03-01

    Presented here is a technique of using Eddy Current based Giant Magneto-Resistance sensor (GMR) to detect surface and sub-layered minute defects in thin films. For surface crack detection, a measurement was performed on a copper metallization of 5-10 microns thick. It was done by scanning the GMR sensor on the surface of the wafer that had two scratches of 0.2 mm, and 2.5 mm in length respectively. In another experiment, metal coatings were deposited over the layers containing five defects with known lengths such that the defects were invisible from the surface. The limit of detection (resolution), in terms of defect size, of the GMR high-resolution Eddy Current probe was studied using this sample. Applications of Eddy Current testing include detecting defects in thin film metallic layers, and quality control of metallization layers on silicon wafers for integrated circuits manufacturing.

  10. A new detection system for extremely small vertically mounted cantilevers

    International Nuclear Information System (INIS)

    Antognozzi, M; Ulcinas, A; Picco, L; Simpson, S H; Miles, M J; Heard, P J; Szczelkun, M D; Brenner, B

    2008-01-01

    Detection techniques currently used in scanning force microscopy impose limitations on the geometrical dimensions of the probes and, as a consequence, on their force sensitivity and temporal response. A new technique, based on scattered evanescent electromagnetic waves (SEW), is presented here that can detect the displacement of the extreme end of a vertically mounted cantilever. The resolution of this method is tested using different cantilever sizes and a theoretical model is developed to maximize the detection sensitivity. The applications presented here clearly show that the SEW detection system enables the use of force sensors with sub-micron size, opening new possibilities in the investigation of biomolecular systems and high speed imaging. Two types of cantilevers were successfully tested: a high force sensitivity lever with a spring constant of 0.17 pN nm -1 and a resonant frequency of 32 kHz; and a high speed lever with a spring constant of 50 pN nm -1 and a resonant frequency of 1.8 MHz. Both these force sensors were fabricated by modifying commercial microcantilevers in a focused ion beam system. It is important to emphasize that these modified cantilevers could not be detected by the conventional optical detection system used in commercial atomic force microscopes

  11. Toxic metal levels in children residing in a smelting craft village in Vietnam: a pilot biomonitoring study.

    Science.gov (United States)

    Sanders, Alison P; Miller, Sloane K; Nguyen, Viet; Kotch, Jonathan B; Fry, Rebecca C

    2014-02-04

    In Vietnam, environmental pollution caused by small-scale domestic smelting of automobile batteries into lead ingot is a growing concern. The village of Nghia Lo is a smelting craft village located roughly 25 km southeast of Hanoi in the Red River Delta. Despite the concern of toxic metal exposure in the village, biomonitoring among susceptible populations, such as children, has not been previously conducted. The aim of this study was to determine the body burden of toxic metals in children residing in a smelting craft village. Twenty children from Nghia Lo, Vietnam, ages 18 months to four years were selected for capillary whole blood and toenail biomonitoring. Whole blood lead levels (BLLs) were measured using a portable lead analyzer, and toenail levels of arsenic, cadmium, chromium, lead, manganese, and mercury were analyzed with inductively coupled plasma-mass spectrometry. The findings show that all of the 20 children had detectable BLLs, and every child had levels that exceeded the Centers for Disease Control and Prevention guideline level of 5 μg/dL. Eighty percent of tested subjects had BLLs higher than 10 μg/dL. Five children (25%) had BLLs greater than 45 μg/dL, the level of recommended medical intervention. In addition to blood lead, all of the children had detectable levels of arsenic, cadmium, chromium, lead, manganese, and mercury in toenail samples. Notably, average toenail lead, manganese, and mercury levels were 157 μg/g, 7.41 μg/g, and 2.63 μg/g respectively, well above levels previously reported in children. Significant Spearman's rank correlations showed that there were relationships between blood and toenail lead levels (r = 0.65, p craft villages in Vietnam are co-exposed to toxic metals. There is an urgent need for mitigation to control metal exposure related to domestic smelting.

  12. Detection of cytoskeletal proteins in small cell lung carcinoma

    Czech Academy of Sciences Publication Activity Database

    Hložánková, M.; Lukáš, Z.; Viklický, Vladimír

    1999-01-01

    Roč. 18, - (1999), s. 47-49 ISSN 0231-5882 Grant - others:MŠk1(CZ) OE10a/EU1450 Keywords : cytoskeletal proteins * small cell lung carcinoma Subject RIV: EI - Biotechnology ; Bionics Impact factor: 0.400, year: 1999

  13. Development of Interactive Multimedia Courseware (e-CRAFT) for Craft Education

    Science.gov (United States)

    Osman, Salyani; Sahari, Noraidah; Zin, Nor Azan Mat

    2012-01-01

    The way of teaching and learning traditional crafts have always used traditional apprenticeship learning methods where the expert facilitates transfer of practice skill sets to novices. As a craft has been taught in conventional approach, the students and experts have been facing several problems especially when expert needs to teach a group of…

  14. Low tube voltage CT for improved detection of pancreatic cancer: detection threshold for small, simulated lesions

    International Nuclear Information System (INIS)

    Holm, Jon; Loizou, Louiza; Albiin, Nils; Kartalis, Nikolaos; Leidner, Bertil; Sundin, Anders

    2012-01-01

    Pancreatic ductal adenocarcinoma is associated with dismal prognosis. The detection of small pancreatic tumors which are still resectable is still a challenging problem. The aim of this study was to investigate the effect of decreasing the tube voltage from 120 to 80 kV on the detection of pancreatic tumors. Three scanning protocols was used; one using the standard tube voltage (120 kV) and current (160 mA) and two using 80 kV but with different tube currents (500 and 675 mA) to achieve equivalent dose (15 mGy) and noise (15 HU) as that of the standard protocol. Tumors were simulated into collected CT phantom images. The attenuation in normal parenchyma at 120 kV was set at 130 HU, as measured previously in clinical examinations, and the tumor attenuation was assumed to differ 20 HU and was set at 110HU. By scanning and measuring of iodine solution with different concentrations the corresponding tumor and parenchyma attenuation at 80 kV was found to be 185 and 219 HU, respectively. To objectively evaluate the differences between the three protocols, a multi-reader multi-case receiver operating characteristic study was conducted, using three readers and 100 cases, each containing 0–3 lesions. The highest reader averaged figure-of-merit (FOM) was achieved for 80 kV and 675 mA (FOM = 0,850), and the lowest for 120 kV (FOM = 0,709). There was a significant difference between the three protocols (p < 0,0001), when making an analysis of variance (ANOVA). Post-hoc analysis (students t-test) shows that there was a significant difference between 120 and 80 kV, but not between the two levels of tube currents at 80 kV. We conclude that when decreasing the tube voltage there is a significant improvement in tumor conspicuity

  15. Detection of small size hepatic hemangioma with SPECT

    International Nuclear Information System (INIS)

    Mana, O.; Zatta, G.; Boccolari, S.; Gallazzi, M.; Tarolo, G.L.; Pisani, A.

    1985-01-01

    A case of a patient with hepatic hemangioma was studied by non-invasive methods. Ultrasonography (US) and computed tomography (CT) studies were able to detect some lesions, but not ascertain the diagnosis. Planar scintigraphy both with 99m Tc-sulfur colloid and with in vivo labelled RBC's did not show the lesions, while single-photon emission tomography (blood pool and sulfur colloid) pointed out their presence and allowed to achieve a correct diagnosis for the biggest lesion (2.5 cm in diameter)

  16. The craft of intensive care medicine.

    Science.gov (United States)

    Carmel, Simon

    2013-06-01

    The practice of medicine is often represented as a dualism: is medicine a 'science' or an 'art'? This dualism has been long-lasting, with evident appeal for the medical profession. It also appears to have been rhetorically powerful, for example in enabling clinicians to resist the encroachment of 'scientific' evidence-based medicine into core areas of medical work such as individual clinical judgement. In this article I want to make the case for a more valid conceptualisation of medical practice: that it is a 'craft' activity. The case I make is founded on a theoretical synthesis of the concept of craft, combined with an analysis of ethnographic observations of routine medical practice in intensive care. For this context the craft aspects of medical work can be seen in how biomedical and other types of knowledge are used in practice, the embodied skills and practical judgement of practitioners and the technological and material environment. These aspects are brought together in two conceptual dimensions for 'craft': first, the application of knowledge; second, interaction with the material world. Some practical and political implications of a 'craft' metaphor for medical practice are noted. © 2013 The Author. Sociology of Health & Illness © 2013 Foundation for the Sociology of Health & Illness/John Wiley & Sons Ltd.

  17. An infrared small target detection method based on multiscale local homogeneity measure

    Science.gov (United States)

    Nie, Jinyan; Qu, Shaocheng; Wei, Yantao; Zhang, Liming; Deng, Lizhen

    2018-05-01

    Infrared (IR) small target detection plays an important role in the field of image detection area owing to its intrinsic characteristics. This paper presents a multiscale local homogeneity measure (MLHM) for infrared small target detection, which can enhance the performance of IR small target detection system. Firstly, intra-patch homogeneity of the target itself and the inter-patch heterogeneity between target and the local background regions are integrated to enhance the significant of small target. Secondly, a multiscale measure based on local regions is proposed to obtain the most appropriate response. Finally, an adaptive threshold method is applied to small target segmentation. Experimental results on three different scenarios indicate that the MLHM has good performance under the interference of strong noise.

  18. Ergonomic Analysis of the Work Condition in Aluminum Crafts Industry

    Science.gov (United States)

    Soewardi, H.; Taufiq, A.; Pradipta, T.

    2017-12-01

    Indonesia has plenty of abundant natural wealth. This natural wealth produces natural materials that can be utilized as a craft product. The craft workers generally still work manually and the work is done repeatedly in one cycle so it is very susceptible to musculoskeletal disorders. Musculoskeletal disorders will cause decrease of worker’s effectiveness and efficiency in completing the task. Thus, this fact has some adverse impact for the company. The purpose of this study is to analyze some task in manufacturing a traditional cooking tool (griddle) which encompasses mold of the griddle, refine of the griddle and the finishing touch by using the Occupational Repetitive Action Index (OCRA index) method. This method consists of high frequency movements, large forces, awkward postures, insufficient resting time and other factor such as vibration. Result of this study shows that in the molding operation, the worker has uncertain and medium risk on right hand in manufacturing small and large size of griddle with OCRA index is 2.5 and 5.3 respectively. In the refining operation the worker has light and medium risk on left hand in manufacturing small and large size with OCRA index is 3.6 and 5.8 using grinding machine and 5.8, 5.2, 6.3 and 5.0 using miser tool. In finishing operation, the worker has high risk on right hand in numbering of code griddle and has medium risk on right hand and medium on left hand in labeling with OCRA index is 9, 6.1 and 6.8 While in assembling operation the worker has no risk. Score that it indicates the risk level of the task in such job. Thus the following actions are to improve the work condition ergonomicly in all operation in alumunium craft.

  19. From Gender-segregated Subjects to Multi-material Craft: Craft Student Teachers’Views on the Future of the Craft Subject

    Directory of Open Access Journals (Sweden)

    Jaana Lepistö

    2015-12-01

    Full Text Available This paper describes the views of student teachers of craft about the future of craft as a school subject. The study was conducted at the University of Turku, Department of Teacher Education, in Rauma in 2014. The literature review revealed that the subject of craft in Finnish basic education is understood as a dialog between the maker and the materials. However, teaching and learning craft in schools and in teacher education has a strong gender-based tradition. The aim of this study is to investigate student teachers’ understanding of craft as a school subject in the future and their solutions to teaching craft in basic education. The data were collected from essays (N = 20 written by student teachers of craft. The essays were analyzed qualitatively using content analysis. The results showed that the student teachers of craft viewed holistic craft, reflective action readiness, entrepreneurial behaviour, multiple skills, the use of versatile materials, and craft as sources of pleasure and the main solutions for the future of craft as a subject.

  20. Doppler method leak detection for LMFBR steam generators. Pt. 1. Experimental results of bubble detection using small models

    International Nuclear Information System (INIS)

    Kumagai, Hiromichi

    1999-01-01

    To prevent the expansion of the tube damage and to maintain structural integrity in the steam generators (SGs) of fast breeder reactors (FBRs), it is necessary to detect precisely and immediately the leakage of water from heat transfer tubes. Therefore, an active acoustic method was developed. Previous studies have revealed that in practical steam generators the active acoustic method can detect bubbles of 10 l/s within 10 seconds. To prevent the expansion of damage to neighboring tubes, it is necessary to detect smaller leakages of water from the heat transfer tubes. The Doppler method is designed to detect small leakages and to find the source of the leak before damage spreads to neighboring tubes. To evaluate the relationship between the detection sensitivity of the Doppler method and the bubble volume and bubble size, the structural shapes and bubble flow conditions were investigated experimentally, using a small structural model. The results show that the Doppler method can detect the bubbles under bubble flow conditions, and it is sensitive enough to detect small leakages within a short time. The doppler method thus has strong potential for the detection of water leakage in SGs. (author)

  1. Nb nanoSQUIDs for detection of small spin systems

    Energy Technology Data Exchange (ETDEWEB)

    Woelbing, R.; Nagel, J.; Kemmler, M.; Kleiner, R.; Koelle, D. [Physikalisches Institut, Universitaet Tuebingen (Germany); Kieler, O.; Weimann, T.; Kohlmann, J.; Zorin, A. [Fachbereich 2.4 ' ' Quantenelektronik' ' , PTB Braunschweig (Germany); Buchter, A.; Xue, F.; Poggio, M. [Department of Physics, University of Basel (Switzerland); Rueffer, D.; Russo-Averchi, E.; Fontcuberta i Morral, A. [Laboratoire des Materiaux Semiconducteurs, EPF Lausanne (Switzerland); Huber, R.; Berberich, P. [Physik-Department E10, Technische Universitaet Muenchen (Germany); Grundler, D. [Laboratoire des Materiaux Semiconducteurs, EPF Lausanne (Switzerland); Physik-Department E10, Technische Universitaet Muenchen (Germany)

    2013-07-01

    We report on the realization of highly sensitive dc nanoSQUIDs for the investigation of small spin systems in moderate magnetic fields. The Nb SQUIDs are based on normal metal Josephson junctions made of HfTi and patterned by e-beam lithography. We demonstrate stable operation up to B = ± 50 mT without degradation of rms flux noise (S{sub Φ}{sup 1/2} ≤ 280 nΦ{sub 0}/√(Hz)). We also present a multifunctional system combining a Nb nanoSQUID and a low-temperature magnetic force microscope (LTMFM) with a Ni nanotube as a scanning tip. This system allows for magnetization measurements of the Ni tube by using both, LTMFM and SQUID readout. Furthermore, the measurement of magnetic flux Φ vs. position of the particle provides an experimental determination of the coupling factor φ{sub μ} = Φ/μ between SQUID and Ni tube with magnetic moment μ. The results confirm our predictions from numerical simulations, taking into account the SQUID geometry.

  2. Overview of craft brewing specificities and potentially associated microbiota.

    Science.gov (United States)

    Rodhouse, Lindsey; Carbonero, Franck

    2017-09-14

    The brewing process differs slightly in craft breweries as compared to industrial breweries, as there are fewer control points. This affects the microbiota of the final product. Beer contains several antimicrobial properties that protect it from pathogens, such as low pH, low oxygen and high carbon dioxide content, and the addition of hops. However, these hurdles have limited power controlling spoilage organisms. Contamination by these organisms can originate in the raw materials, persist in the environment, and be introduced by using flavoring ingredients later in the process. Spoilage is a prominent issue in brewing, and can cause quality degradation resulting in consumer rejection and product waste. For example, lactic acid bacteria are predominately associated with producing a ropy texture and haze, along with producing diacetyl which gives the beer butter flavor notes. Other microorganisms may not affect flavor or aroma, but can retard fermentation by consuming nutrients needed by fermentation yeast. Quality control in craft breweries today relies on culturing methods to detect specific spoilage organisms. Using media can be beneficial for detecting the most common beer spoilers, such as Lactobacillus and Pediococci. However, these methods are time consuming with long incubation periods. Molecular methods such as community profiling or high throughput sequencing are better used for identifying entire populations of beer. These methods allow for detection, differentiation, and identification of taxa.

  3. Crafting by concepts fiber arts and mathematics

    CERN Document Server

    Belcastro, Sarah-Marie

    2016-01-01

    From the editors of the popular Making Mathematics with Needlework, this book presents projects that highlight the relationship between types of needlework and mathematics. Chapters start with accessible overviews presenting the interplay between mathematical concepts and craft expressions. Following sections explain the mathematics in more detail, and provide suggestions for classroom activities. Each chapter ends with specific crafting instructions. Types of needlework included are knitting, crochet, needlepoint, cross-stitch, quilting, temari balls, beading, tatting, and string art. Instructions are written as ordinary patterns, so the formatting and language will be familiar to crafters.

  4. Friedel-Crafts Acylation with Amides

    Science.gov (United States)

    Raja, Erum K.; DeSchepper, Daniel J.; Nilsson Lill, Sten O.; Klumpp, Douglas A.

    2012-01-01

    Friedel-Crafts acylation has been known since the 1870s and it is an important organic synthetic reaction leading to aromatic ketone products. Friedel-Crafts acylation is usually done with carboxylic acid chlorides or anhydrides while amides are generally not useful substrates in these reactions. Despite being the least reactive carboxylic acid derivative, we have found a series of amides capable of providing aromatic ketones in good yields (55–96%, 17 examples). We propose a mechanism involving diminished C-N resonance through superelectrophilic activation and subsequent cleavage to acyl cations. PMID:22690740

  5. DETECTION OF BACTERIAL SMALL TRANSCRIPTS FROM RNA-SEQ DATA: A COMPARATIVE ASSESSMENT.

    Science.gov (United States)

    Peña-Castillo, Lourdes; Grüell, Marc; Mulligan, Martin E; Lang, Andrew S

    2016-01-01

    Small non-coding RNAs (sRNAs) are regulatory RNA molecules that have been identified in a multitude of bacterial species and shown to control numerous cellular processes through various regulatory mechanisms. In the last decade, next generation RNA sequencing (RNA-seq) has been used for the genome-wide detection of bacterial sRNAs. Here we describe sRNA-Detect, a novel approach to identify expressed small transcripts from prokaryotic RNA-seq data. Using RNA-seq data from three bacterial species and two sequencing platforms, we performed a comparative assessment of five computational approaches for the detection of small transcripts. We demonstrate that sRNA-Detect improves upon current standalone computational approaches for identifying novel small transcripts in bacteria.

  6. 46 CFR 199.230 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 199.230 Section 199.230... Stowage of survival craft. (a) To meet the requirements of § 199.130(b)(1), each lifeboat on a passenger... height of a survival craft must take into account the vessel's escape provisions, the vessel's size, and...

  7. 46 CFR 180.200 - Survival craft-general.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-general. 180.200 Section 180.200 Shipping...) LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 180.200 Survival craft—general. (a) Each survival craft required on a vessel by this part must meet one of the following: (1) For an...

  8. 46 CFR 180.150 - Survival craft embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation arrangements. 180.150 Section... (UNDER 100 GROSS TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 180.150 Survival craft embarkation arrangements. (a) A launching appliance approved under approval...

  9. 47 CFR 97.215 - Telecommand of model craft.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Telecommand of model craft. 97.215 Section 97... AMATEUR RADIO SERVICE Special Operations § 97.215 Telecommand of model craft. An amateur station transmitting signals to control a model craft may be operated as follows: (a) The station identification...

  10. 75 FR 50773 - Invocation of Sunken Military Craft Act

    Science.gov (United States)

    2010-08-17

    ... Military Craft Act AGENCY: Coast Guard, DHS. ACTION: Notice. SUMMARY: The Coast Guard is announcing that a C-130 aircraft which crashed off the coast of California is a sunken military craft. It is therefore... is announcing that the wreckage of CG 1705 is a sunken military craft, and is therefore protected...

  11. 46 CFR 108.530 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 108.530 Section 108.530... AND EQUIPMENT Lifesaving Equipment § 108.530 Stowage of survival craft. (a) General. Each survival craft required to be served by a launching appliance or marine evacuation system must be stowed as...

  12. 46 CFR 199.290 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Stowage of survival craft. 199.290 Section 199.290... of survival craft. (a) To meet the requirements of § 199.130(b)(1), each lifeboat— (1) On a cargo... required under § 199.261(e), no stowage position or muster and embarkation station for a survival craft on...

  13. 46 CFR 122.518 - Inflatable survival craft placards.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Inflatable survival craft placards. 122.518 Section 122... Preparations for Emergencies § 122.518 Inflatable survival craft placards. (a) Every vessel equipped with an inflatable survival craft must have approved placards or other cards containing instructions for launching...

  14. 32 CFR 700.872 - Ships and craft in drydock.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Ships and craft in drydock. 700.872 Section 700... Special Circumstances/ships in Naval Stations and Shipyards § 700.872 Ships and craft in drydock. (a) The... ship or craft, not in commission, is in a naval drydock, the provisions of this article shall apply...

  15. 33 CFR 401.58 - Pleasure craft scheduling.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pleasure craft scheduling. 401.58... OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.58 Pleasure craft scheduling. (a) The transit of pleasure craft shall be scheduled by the traffic controller or the officer in...

  16. 29 CFR 1202.8 - Hearings on craft or class.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Hearings on craft or class. 1202.8 Section 1202.8 Labor... craft or class. In the event the contesting parties or organizations are unable to agree on the..., specifying the craft or class of employees eligible to participate in the designation of representatives. ...

  17. 46 CFR 108.525 - Survival craft number and arrangement.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft number and arrangement. 108.525 Section... UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.525 Survival craft number and arrangement. (a... arrangement of survival craft: (1) Lifeboats with an aggregate capacity to accommodate the total number of...

  18. 46 CFR 185.518 - Inflatable survival craft placards.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Inflatable survival craft placards. 185.518 Section 185... 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.518 Inflatable survival craft placards. (a) Every vessel equipped with an inflatable survival craft must have approved placards or other...

  19. 46 CFR 28.125 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Stowage of survival craft. 28.125 Section 28.125... FISHING INDUSTRY VESSELS Requirements for All Vessels § 28.125 Stowage of survival craft. (a) Each..., inflatable buoyant apparatus, and any auxiliary craft used in their place, must be kept readily accessible...

  20. 46 CFR 28.130 - Survival craft equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Survival craft equipment. 28.130 Section 28.130 Shipping... INDUSTRY VESSELS Requirements for All Vessels § 28.130 Survival craft equipment. (a) General. Each item of survival craft equipment must be of good quality, effective for the purpose it is intended to serve, and...

  1. 47 CFR 80.1095 - Survival craft equipment.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Survival craft equipment. 80.1095 Section 80... for Ship Stations § 80.1095 Survival craft equipment. (a) At least three two-way VHF radiotelephone... they can be rapidly placed in any survival craft other than life rafts required by Regulation III/26.1...

  2. 46 CFR 28.805 - Launching of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Launching of survival craft. 28.805 Section 28.805... FISHING INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.805 Launching of survival craft. In addition to the survival craft requirements in subpart B, each vessel must have a gate or other opening in the...

  3. The alignment of product strategy to supply chain practices of craft businesses in Gauteng Province, South Africa

    Directory of Open Access Journals (Sweden)

    Craig Voortman

    2014-11-01

    Full Text Available External factors such as blurring market boundaries, escalating customer diversity and increasing global competitive threats have forced businesses to build strategies around key products and formulate market-driven strategies that are integrated with relationship and supply chain strategies to deliver superior customer value. Indeed, in the modern era of supply chain management, organisations are getting more integrated with their suppliers and customers as a way to manage the total supply chain. The purpose of this research was to determine if product strategies and supply chain practices of small craft business are aligned. Personal in-depth interviews were conducted with nine craft businesses operating in Gauteng Province, South Africa. The findings revealed that craft businesses struggle to match their product strategies with their supply chain strategies. Craft businesses also exhibited some inbound supply chain weaknesses.

  4. Detection of small targets in a marine environment using laser radar

    NARCIS (Netherlands)

    Kunz, G.J.; Bekman, H.H.P.T.; Benoist, K.W.; Cohen, L.H.; Heuvel, J.C. van den; Putten, F.J.M.

    2005-01-01

    Small maritime targets, e.g., periscope tubes, jet skies, swimmers and small boats, are potential threats for naval ships under many conditions, but are difficult to detect with current radar systems due to their limited radar cross section and the presence of sea clutter. On the other hand,

  5. The Art and Craft of Science

    Science.gov (United States)

    Root-Bernstein, Robert; Root-Bernstein, Michele

    2013-01-01

    Walter Alvarez, a doctor and physiologist of some renown, decided to send his scientifically talented son, Luis, to an arts and crafts school where Luis took industrial drawing and woodworking instead of calculus. Luis Alvarez won the Nobel Prize in physics in 1968. Einstein was certainly not a standout in his mathematics and physics classes. Yet…

  6. Craft Knowledge: Of Disciplinarity in Writing Studies

    Science.gov (United States)

    Johnson, Robert R.

    2010-01-01

    This article argues that craft knowledge can provide a disciplinary rationale for writing studies. It draws from the ancient concepts of teche, phronesis, and the four causes of making and makes the case for a definition of disciplinary knowledge fitting for writing studies. The article concludes with a conceptual framework that can serve as a…

  7. Rationalizing Cooperation: Moroccan Craft, Politics, and Education

    Science.gov (United States)

    Nicholas, Claire

    2018-01-01

    State attempts to rationalize Moroccan craft education reflect the ambivalent status of traditional knowledge in a modern economy. Female artisans, recently organized as a cooperative, navigate this ambivalence in a weaving "theory" class and in their "occupation" of the cooperative structure itself. During performances of…

  8. The nature of creativity in craft

    DEFF Research Database (Denmark)

    Glaveanu, Vlad Petre

    2012-01-01

    The present article explores the nature of creativity in craft and does so with the help of a case study of traditional Easter egg decoration. It starts by positioning the domain of folk art in relation to fine art and within a larger category of everyday life forms of creative expression...

  9. Antecedents of daily team job crafting

    NARCIS (Netherlands)

    Mäkikangas, Anne; Bakker, Arnold B.; Schaufeli, Wilmar B.

    2017-01-01

    This study investigated potential antecedents of team job crafting defined as the extent to which team members engage together in increasing (social and structural) job resources and challenges, and decreasing hindering job demands. Mindful of the teamwork literature, we hypothesized that individual

  10. TEM10 homodyne detection as an optimal small-displacement and tilt-measurement scheme

    DEFF Research Database (Denmark)

    Delaubert, Vincent; Treps, Nikolas; Lassen, Mikael Østergaard

    2006-01-01

    We report an experimental demonstration of optimal measurements of small displacement and tilt of a Gaussian beam - two conjugate variables - involving a homodyne detection with a TEM10 local oscillator. We verify that the standard split detection is only 64% efficient. We also show a displacement...

  11. Meaningful work and work engagement : The mediating role of perceived opportunity to craft and job crafting behavior

    NARCIS (Netherlands)

    Van Wingerden, Jessica; van der Stoep, Joost; Poell, R.F.

    2018-01-01

    This study examines the impact of meaningful work on employees’ level of work engagement as mediated by perceived opportunities to craft and job crafting. Based on the literature on meaningful work and job crafting, we hypothesize that meaningful work has a positive relationship with an employee’s

  12. Small Displacement Detection of Biological Signals Using the Cyclic Frequency Method

    Directory of Open Access Journals (Sweden)

    Dan Zhang

    2015-01-01

    Full Text Available A new signal processing method called the Cyclic Frequency method is proposed for small displacement detection of vital signals such as heart rate and respiration using the CW radar method. We have presented experimental results of small displacement detection to confirm the validity of the method. The displacement amplitude 2.5 mm can be detected with a propagation frequency of 24.15 GHz. We may increase the propagation frequency for smaller displacement amplitude or target velocity.

  13. Active acoustic leak detection for LMFBR steam generators. Pt. 7. Potential for small leak detection

    International Nuclear Information System (INIS)

    Kumagai, Hiromichi; Yoshida, Kazuo

    1998-01-01

    In order to prevent the expansion of tube damage and to maintain structural integrity in the steam generators (SGs) of fast breeder reactors (FBR), it is necessary to detect precisely and immediately the leakage of water from heat transfer tubes. Therefore, an active acoustic method, which detects the sound attenuation due to bubbles generated in the sodium-water reactions, is being developed. Previous studies have revealed that the active acoustic method can detect bubbles of 10 l/s (equivalence water leak rate about 10 g/s) within 10 seconds in practical steam generators. In order to prevent the expansion of damage to neighboring tubes, however, it is necessary to detect smaller leakage of water from heat transfer tubes. In this study, in order to evaluate the detection sensitivity of the active method, the signal processing methods for emitter and receiver sound and the detection method for leakage within 1 g/s are investigated experimentally, using an SG full-sector model that simulates the actual SGs. A typical result shows that detection of 0.4 l/s air bubbles (equivalent water leak rate about 0.4 g/s) takes about 80 seconds, which is shorter than the propagation time of damage to neighboring tubes. (author)

  14. Detection of small surface defects using DCT based enhancement approach in machine vision systems

    Science.gov (United States)

    He, Fuqiang; Wang, Wen; Chen, Zichen

    2005-12-01

    Utilizing DCT based enhancement approach, an improved small defect detection algorithm for real-time leather surface inspection was developed. A two-stage decomposition procedure was proposed to extract an odd-odd frequency matrix after a digital image has been transformed to DCT domain. Then, the reverse cumulative sum algorithm was proposed to detect the transition points of the gentle curves plotted from the odd-odd frequency matrix. The best radius of the cutting sector was computed in terms of the transition points and the high-pass filtering operation was implemented. The filtered image was then inversed and transformed back to the spatial domain. Finally, the restored image was segmented by an entropy method and some defect features are calculated. Experimental results show the proposed small defect detection method can reach the small defect detection rate by 94%.

  15. Automatically detect and track infrared small targets with kernel Fukunaga-Koontz transform and Kalman prediction

    Science.gov (United States)

    Liu, Ruiming; Liu, Erqi; Yang, Jie; Zeng, Yong; Wang, Fanglin; Cao, Yuan

    2007-11-01

    Fukunaga-Koontz transform (FKT), stemming from principal component analysis (PCA), is used in many pattern recognition and image-processing fields. It cannot capture the higher-order statistical property of natural images, so its detection performance is not satisfying. PCA has been extended into kernel PCA in order to capture the higher-order statistics. However, thus far there have been no researchers who have definitely proposed kernel FKT (KFKT) and researched its detection performance. For accurately detecting potential small targets from infrared images, we first extend FKT into KFKT to capture the higher-order statistical properties of images. Then a framework based on Kalman prediction and KFKT, which can automatically detect and track small targets, is developed. Results of experiments show that KFKT outperforms FKT and the proposed framework is competent to automatically detect and track infrared point targets.

  16. From Gender-segregated Subjects to Multi-material Craft: Craft Student Teachers’Views on the Future of the Craft Subject

    OpenAIRE

    Jaana Lepistö; Eila Lindfors

    2015-01-01

    This paper describes the views of student teachers of craft about the future of craft as a school subject. The study was conducted at the University of Turku, Department of Teacher Education, in Rauma in 2014. The literature review revealed that the subject of craft in Finnish basic education is understood as a dialog between the maker and the materials. However, teaching and learning craft in schools and in teacher education has a strong gender-based tradition. The aim of this study is to in...

  17. High-resolution remotely sensed small target detection by imitating fly visual perception mechanism.

    Science.gov (United States)

    Huang, Fengchen; Xu, Lizhong; Li, Min; Tang, Min

    2012-01-01

    The difficulty and limitation of small target detection methods for high-resolution remote sensing data have been a recent research hot spot. Inspired by the information capture and processing theory of fly visual system, this paper endeavors to construct a characterized model of information perception and make use of the advantages of fast and accurate small target detection under complex varied nature environment. The proposed model forms a theoretical basis of small target detection for high-resolution remote sensing data. After the comparison of prevailing simulation mechanism behind fly visual systems, we propose a fly-imitated visual system method of information processing for high-resolution remote sensing data. A small target detector and corresponding detection algorithm are designed by simulating the mechanism of information acquisition, compression, and fusion of fly visual system and the function of pool cell and the character of nonlinear self-adaption. Experiments verify the feasibility and rationality of the proposed small target detection model and fly-imitated visual perception method.

  18. High-Resolution Remotely Sensed Small Target Detection by Imitating Fly Visual Perception Mechanism

    Directory of Open Access Journals (Sweden)

    Fengchen Huang

    2012-01-01

    Full Text Available The difficulty and limitation of small target detection methods for high-resolution remote sensing data have been a recent research hot spot. Inspired by the information capture and processing theory of fly visual system, this paper endeavors to construct a characterized model of information perception and make use of the advantages of fast and accurate small target detection under complex varied nature environment. The proposed model forms a theoretical basis of small target detection for high-resolution remote sensing data. After the comparison of prevailing simulation mechanism behind fly visual systems, we propose a fly-imitated visual system method of information processing for high-resolution remote sensing data. A small target detector and corresponding detection algorithm are designed by simulating the mechanism of information acquisition, compression, and fusion of fly visual system and the function of pool cell and the character of nonlinear self-adaption. Experiments verify the feasibility and rationality of the proposed small target detection model and fly-imitated visual perception method.

  19. An improved approach to exchange non-rectangular departments in CRAFT algorithm

    OpenAIRE

    Esmaeili Aliabadi, Danial; Pourghannad, Behrooz

    2012-01-01

    In this Paper, an algorithm which improves CRAFT algorithm’s efficacy is developed. CRAFT is an algorithm widely used to solve facility layout problems. Our proposed method, named Plasma, can be used to improve CRAFT results. In this note, Plasma algorithm is tested in several sample problems. The comparison between Plasma and classic CRAFT and also Micro-CRAFT indicates that Plasma is successful in cost reduction in comparison with CRAFT and Micro-CRAFT.

  20. Sustainable Innovation of Glass Design and Craft

    DEFF Research Database (Denmark)

    Sparre-Petersen, Maria

    2014-01-01

    Barely any research has been made into the implementation of sustainable principles in glass design and craft. A common tendency among students and practitioners is to consider it problematic if not impossible to develop a “truly sustainable practice”. Generally glass crafts people and glass...... designers aim to explore new aesthetic possibilities for the material and see sustainability as a hindrance for aesthetic freedom. On the contrary the field of design has strong and growing emphasis on sustainable development. Fry (2009) argues that what he defines as sustain-ability is not an end goal...... but an ongoing process of re-directing the way we design our world and thereby our future. This approach along with further research into sustainable development within the field of design and combined with material specific methodologies may reveal new possibilities for sustainable as well as aesthetic...

  1. Application of CRAFT (complete reduction to amplitude frequency table) in nonuniformly sampled (NUS) 2D NMR data processing.

    Science.gov (United States)

    Krishnamurthy, Krish; Hari, Natarajan

    2017-09-15

    The recently published CRAFT (complete reduction to amplitude frequency table) technique converts the raw FID data (i.e., time domain data) into a table of frequencies, amplitudes, decay rate constants, and phases. It offers an alternate approach to decimate time-domain data, with minimal preprocessing step. It has been shown that application of CRAFT technique to process the t 1 dimension of the 2D data significantly improved the detectable resolution by its ability to analyze without the use of ubiquitous apodization of extensively zero-filled data. It was noted earlier that CRAFT did not resolve sinusoids that were not already resolvable in time-domain (i.e., t 1 max dependent resolution). We present a combined NUS-IST-CRAFT approach wherein the NUS acquisition technique (sparse sampling technique) increases the intrinsic resolution in time-domain (by increasing t 1 max), IST fills the gap in the sparse sampling, and CRAFT processing extracts the information without loss due to any severe apodization. NUS and CRAFT are thus complementary techniques to improve intrinsic and usable resolution. We show that significant improvement can be achieved with this combination over conventional NUS-IST processing. With reasonable sensitivity, the models can be extended to significantly higher t 1 max to generate an indirect-DEPT spectrum that rivals the direct observe counterpart. Copyright © 2017 John Wiley & Sons, Ltd.

  2. Concept annotation in the CRAFT corpus.

    Science.gov (United States)

    Bada, Michael; Eckert, Miriam; Evans, Donald; Garcia, Kristin; Shipley, Krista; Sitnikov, Dmitry; Baumgartner, William A; Cohen, K Bretonnel; Verspoor, Karin; Blake, Judith A; Hunter, Lawrence E

    2012-07-09

    Manually annotated corpora are critical for the training and evaluation of automated methods to identify concepts in biomedical text. This paper presents the concept annotations of the Colorado Richly Annotated Full-Text (CRAFT) Corpus, a collection of 97 full-length, open-access biomedical journal articles that have been annotated both semantically and syntactically to serve as a research resource for the biomedical natural-language-processing (NLP) community. CRAFT identifies all mentions of nearly all concepts from nine prominent biomedical ontologies and terminologies: the Cell Type Ontology, the Chemical Entities of Biological Interest ontology, the NCBI Taxonomy, the Protein Ontology, the Sequence Ontology, the entries of the Entrez Gene database, and the three subontologies of the Gene Ontology. The first public release includes the annotations for 67 of the 97 articles, reserving two sets of 15 articles for future text-mining competitions (after which these too will be released). Concept annotations were created based on a single set of guidelines, which has enabled us to achieve consistently high interannotator agreement. As the initial 67-article release contains more than 560,000 tokens (and the full set more than 790,000 tokens), our corpus is among the largest gold-standard annotated biomedical corpora. Unlike most others, the journal articles that comprise the corpus are drawn from diverse biomedical disciplines and are marked up in their entirety. Additionally, with a concept-annotation count of nearly 100,000 in the 67-article subset (and more than 140,000 in the full collection), the scale of conceptual markup is also among the largest of comparable corpora. The concept annotations of the CRAFT Corpus have the potential to significantly advance biomedical text mining by providing a high-quality gold standard for NLP systems. The corpus, annotation guidelines, and other associated resources are freely available at http://bionlp-corpora.sourceforge.net/CRAFT/index.shtml.

  3. Crafted - meisterdatud / Mihkel Tüür

    Index Scriptorium Estoniae

    Tüür, Mihkel, 1976-

    2012-01-01

    12. Alvar Aalto sümpoosion Jyväskyläs 10.-12. augustil 2012 teemal "Crafted". Kuraator Pekka Heikkinen. Pikemalt Mohsen Mostafavi ettekandest "Arhitektuur on materiaalne" ja Jürg Conzetti ettekandest "Strukturaalse tava jätkamine". Autori sõnul jäi kõlama mõte, et meisterlikult ehitatud maja saab olla ainus arhitektuuri tegelik mõõde

  4. Blu-ray based optomagnetic aptasensor for detection of small molecules

    DEFF Research Database (Denmark)

    Yang, Jaeyoung; Donolato, Marco; Pinto, Alessandro

    2016-01-01

    This paper describes an aptamer-based optomagnetic biosensor for detection of a small molecule based on target binding-induced inhibition of magnetic nanoparticle (MNP) clustering. For the detection of a target small molecule, two mutually exclusive binding reactions (aptamer-target binding...... the hydrodynamic size distribution of MNPs and their clusters. A commercial Blu-ray optical pickup unit is used for optical signal acquisition, which enables the establishment of a low-cost and miniaturized biosensing platform. Experimental results show that the degree of MNP clustering correlates well...

  5. A small-angle large-acceptance detection system for hadrons

    Science.gov (United States)

    Kalantar-Nayestanaki, N.; Bacelar, J. C. S.; Brandenburg, S.; Huisman, H.; Messchendorp, J. G.; Mul, F. A.; Schadmand, S.; van der Schaaf, K.; Schippers, J. M.; Volkerts, M.

    2000-04-01

    The performance of a segmented large-acceptance detector, capable of measuring particles at small forward angles, is presented. The Small-Angle Large-Acceptance Detector (SALAD), was built to handle very high rates of particles impinging on the detector. Particles down to a few MeV can be detected with it. The position of charged particles is measured by two Multi-Wire Proportional Chambers while scintillator blocks are used to measure the energy of the detected particle. A stack of thin scintillators placed behind the energy detectors allows for a hardware rejection (veto) of high-energy particles going through the scintillator blocks.

  6. A small-angle large-acceptance detection system for hadrons

    CERN Document Server

    Kalantar-Nayestanaki, N; Brandenburg, S; Huisman, H; Messchendorp, J G; Mul, F A; Schadmand, S; Schaaf, K V D; Schippers, J M; Volkerts, M

    2000-01-01

    The performance of a segmented large-acceptance detector, capable of measuring particles at small forward angles, is presented. The Small-Angle Large-Acceptance Detector (SALAD), was built to handle very high rates of particles impinging on the detector. Particles down to a few MeV can be detected with it. The position of charged particles is measured by two Multi-Wire Proportional Chambers while scintillator blocks are used to measure the energy of the detected particle. A stack of thin scintillators placed behind the energy detectors allows for a hardware rejection (veto) of high-energy particles going through the scintillator blocks.

  7. A small-angle large-acceptance detection system for hadrons

    International Nuclear Information System (INIS)

    Kalantar-Nayestanaki, N.; Bacelar, J.C.S.; Brandenburg, S.; Huisman, H.; Messchendorp, J.G.; Mul, F.A.; Schadmand, S.; Schaaf, K. van der; Schippers, J.M.; Volkerts, M.

    2000-01-01

    The performance of a segmented large-acceptance detector, capable of measuring particles at small forward angles, is presented. The Small-Angle Large-Acceptance Detector (SALAD), was built to handle very high rates of particles impinging on the detector. Particles down to a few MeV can be detected with it. The position of charged particles is measured by two Multi-Wire Proportional Chambers while scintillator blocks are used to measure the energy of the detected particle. A stack of thin scintillators placed behind the energy detectors allows for a hardware rejection (veto) of high-energy particles going through the scintillator blocks

  8. The meanings of craft to an occupational therapist.

    Science.gov (United States)

    Harris, Emma

    2008-06-01

    Craft was the first therapeutic occupation of occupational therapy. Since the early days of the profession, the value of craft in practice is a topic that has been discussed with fluctuating interest. Recent discussions by occupational therapists have reinforced that although craft is relevant to occupational therapy, there are uncertainties about its place in contemporary practice. Presently, scholars have identified that occupation is both the center of human experience and the core of our profession. Therefore, this study aimed to begin to clarify the meaning of craft to practice today by gaining a deep understanding of the meanings that one occupational therapist attributes to craft. Using narrative inquiry, data were gathered through a conversation held between the research participant and myself. A reflexive journal was also kept to support this data gathering process. Narrative analysis enabled intimate engagement with the data and the emergence of themes and sub-themes. The findings, in the form of an interpretive story, suggest first, that craft-making has therapeutic value; second, that reasoning about the therapeutic use of craft is similar to reasoning about other therapeutic activities; and third, that personal experience with craft-making can influence the selection of craft as therapeutic media. From this study, further research into the impact personal and professional experiences can have on choice of therapeutic media and an analysis of the sociopolitical context of the meanings that occupational therapists attribute to craft-making is suggested.

  9. Detection of structural defects in lecithin membranes by the small-angle neutron scattering method

    International Nuclear Information System (INIS)

    Bezzabotnov, V.Yu.; Gordelij, V.I.; Ostanevich, Yu.M.; Yaguzhinskij, L.S.

    1989-01-01

    Irregularities interpreted as interdomain defects have been detected in model lipid membranes of dipalmitoil lecithin in liquid L α -phase by the method of small-angle scattering (lateral diffraction). The dimensions and concentrations of the defects were about those supposed within the dynamic cluster model of bilayer (Ivkov, 1984). No irregularities were detected in the solid Lβ ' -phase (the diffusion scattering intensity was at least ten times less)

  10. An alkaline separation method for detection of small amount of DNA damage

    International Nuclear Information System (INIS)

    Sakai, Kazuo; Okada, Shigefumi

    1981-01-01

    An alkaline separation technique originally established by Ahnstroem is modified to detect small amount of DNA damage in X-irradiated mouse leukemic L5178Y cells. It is made quantitative by calibration with an alkaline sucrose gradient centrifugation. The present method would make it possible to study DNA damage and its repair within a dose range of X-rays where cell survival and mutation are usually investigated. It is also useful for detecting DNA damage caused by chemicals. (author)

  11. Technique for detecting a small magnitude loss of special nuclear material

    International Nuclear Information System (INIS)

    Pike, D.H.; Chernick, M.R.; Downing, D.J.

    The detection of losses of special nuclear materials has been the subject of much research in recent years. The standard industry practice using ID/LEID will detect large magnitude losses. Time series techniques such as the Kalman Filter or CUSUM methods will detect small magnitude losses if they occur regularly over a sustained period of time. To date no technique has been proposed which adequately addresses the problem of detecting a small magnitude loss occurring in a single period. This paper proposes a method for detecting a small magnitude loss. The approach makes use of the influence function of Hempel. The influence function measures the effect of a single inventory difference on a group of statistics. An inventory difference for a period in which a loss occurs can be expected to produce an abnormality in the calculated statistics. This abnormality is measurable by the influence function. It is shown that a one period loss smaller in magnitude than the LEID can be detected using this approach

  12. Leading to Crafting: The Relation Between Leadership Perception and Nurses' Job Crafting.

    Science.gov (United States)

    Esteves, Tiago; Pereira Lopes, Miguel

    2017-06-01

    Whenever individuals adapt their jobs to make them closer of their personal preferences, they are performing job crafting. This study aims to investigate if the way nurses perceive their leaders' behaviors is related with job crafting development. To do so, a quantitative analysis was conducted among a group of 325 Portuguese nurses. Results indicate that the perception of an empowering leader was found to be strongly related with the increase of challenges in the work environment, and with the development of stronger relations with direct managers and co-workers, which are two job crafting dimensions. The perception of a directive leader was found to be positively related with the avoidance of performing hindering tasks. Strengthening relations with direct managers and co-workers was found to be particularly related to leadership perception. Theoretical and practical implications are discussed.

  13. Detection of small-size planetary candidates with CoRoT data

    Directory of Open Access Journals (Sweden)

    Moutou C.

    2011-02-01

    Full Text Available With the discovery of CoRoT-7b, the first transiting super-Earth, the CoRoT space mission has shown the capability to detect short-period rocky planets around solar-like stars. By performing a blind test with real CoRoT light curves, we want to establish the detection threshold of small-size planets in CoRoT data. We investigate the main obstacles to the detection of transiting super-Earths in CoRoT data, notably the presence of short-time scale variability and hot pixels.

  14. Visual SLAM and Moving-object Detection for a Small-size Humanoid Robot

    Directory of Open Access Journals (Sweden)

    Yin-Tien Wang

    2010-09-01

    Full Text Available In the paper, a novel moving object detection (MOD algorithm is developed and integrated with robot visual Simultaneous Localization and Mapping (vSLAM. The moving object is assumed to be a rigid body and its coordinate system in space is represented by a position vector and a rotation matrix. The MOD algorithm is composed of detection of image features, initialization of image features, and calculation of object coordinates. Experimentation is implemented on a small-size humanoid robot and the results show that the performance of the proposed algorithm is efficient for robot visual SLAM and moving object detection.

  15. Job Crafting, Employee Well-being, and Quality of Care.

    Science.gov (United States)

    Yepes-Baldó, Montserrat; Romeo, Marina; Westerberg, Kristina; Nordin, Maria

    2018-01-01

    The main objective is to study the effects of job crafting activities of elder care and nursing home employees on their perceived well-being and quality of care in two European countries, Spain and Sweden. The Job Crafting, the General Health, and the Quality of Care questionnaires were administered to 530 employees. Correlations and hierarchical regression analyses were performed. Results confirm the effects of job crafting on quality of care ( r = .291, p employees' well-being ( r = .201, p well-being in Spain and Sweden and with quality of care in Spain. On the contrary, in Sweden, the relationship between job crafting and well-being was not linear. Job crafting contributes significantly to employees' and residents' well-being. Management should promote job crafting to co-create meaningful and productive work. Cultural effects are proposed to explain the differences found.

  16. Results from the search-lidar demonstrator project for detection of small Sea-Surface targets

    NARCIS (Netherlands)

    Heuvel, J.C. van den; Putten, F.J.M. van; Cohen, L.H.; Kemp, R.A.W.; Franssen, G.C.

    2009-01-01

    Coastal surveillance and naval operations in the littoral both have to deal with the threat of small sea-surface targets. These targets have a low radar cross-section and a low velocity that makes them hard to detect by radar. Typical threats include jet skis, FIAC's, and speedboats. Previous lidar

  17. Search-Lidar Demonstrator for Detection of Small Sea-Surface Targets

    NARCIS (Netherlands)

    Heuvel, J.C. van den; Bekman, H.H.P.T.; Putten, F.J.M. van; Cohen, L.H.; Schleijpen, H.M.A.

    2008-01-01

    Coastal surveillance and naval operations in the littoral both have to deal with the threat of small sea-surface targets. These targets have a low radar cross-section and a low velocity that makes them hard to detect by radar. Typical threats include jet skis, FIAC’s, and speedboats. Lidar

  18. Detection of Small Sea-Surface Targets with a Search Lidar

    NARCIS (Netherlands)

    Heuvel, J.C. van den; Bekman, H.H.P.T.; Putten, F.J.M.; Cohen, L.A.

    2007-01-01

    Naval operations in the littoral have to deal with the threat of small sea-surface targets. These targets have a low radar cross-section and low velocity, which makes them hard to detect by radar in the presence of sea clutter. Typical threats include periscopes, jet skies, FIAC’s, and speedboats.

  19. Robust Small Target Co-Detection from Airborne Infrared Image Sequences.

    Science.gov (United States)

    Gao, Jingli; Wen, Chenglin; Liu, Meiqin

    2017-09-29

    In this paper, a novel infrared target co-detection model combining the self-correlation features of backgrounds and the commonality features of targets in the spatio-temporal domain is proposed to detect small targets in a sequence of infrared images with complex backgrounds. Firstly, a dense target extraction model based on nonlinear weights is proposed, which can better suppress background of images and enhance small targets than weights of singular values. Secondly, a sparse target extraction model based on entry-wise weighted robust principal component analysis is proposed. The entry-wise weight adaptively incorporates structural prior in terms of local weighted entropy, thus, it can extract real targets accurately and suppress background clutters efficiently. Finally, the commonality of targets in the spatio-temporal domain are used to construct target refinement model for false alarms suppression and target confirmation. Since real targets could appear in both of the dense and sparse reconstruction maps of a single frame, and form trajectories after tracklet association of consecutive frames, the location correlation of the dense and sparse reconstruction maps for a single frame and tracklet association of the location correlation maps for successive frames have strong ability to discriminate between small targets and background clutters. Experimental results demonstrate that the proposed small target co-detection method can not only suppress background clutters effectively, but also detect targets accurately even if with target-like interference.

  20. FMCW radar system for detection and classification of small vessels in high sea state conditions

    NARCIS (Netherlands)

    Wasselin, J.-P.; Mazuel, S.; Itcia, E.; Huizing, A.G.; Theil, A.

    2012-01-01

    The ROCKWELL COLLINS France radar department is currently developing a FMCW radar system for the detection and the classification of small maritime targets in the frame of the SISMARIS, SARGOS & I2C projects. Several test campaigns have been conducted since 2009 to develop a sensor as well as an

  1. Chaos characteristics and least squares support vector machines based online pipeline small leakages detection

    International Nuclear Information System (INIS)

    Liu, Jinhai; Su, Hanguang; Ma, Yanjuan; Wang, Gang; Wang, Yuan; Zhang, Kun

    2016-01-01

    Small leakages are severe threats to the long distance pipeline transportation. An online small leakage detection method based on chaos characteristics and Least Squares Support Vector Machines (LS-SVMs) is proposed in this paper. For the first time, the relationship between the chaos characteristics of pipeline inner pressures and the small leakages is investigated and applied in the pipeline detection method. Firstly, chaos in the pipeline inner pressure is found. Relevant chaos characteristics are estimated by the nonlinear time series analysis package (TISEAN). Then LS-SVM with a hybrid kernel is built and named as hybrid kernel LS-SVM (HKLS-SVM). It is applied to analyze the chaos characteristics and distinguish the negative pressure waves (NPWs) caused by small leaks. A new leak location method is also expounded. Finally, data of the chaotic Logistic-Map system is used in the simulation. A comparison between HKLS-SVM and other methods, in terms of the identification accuracy and computing efficiency, is made. The simulation result shows that HKLS-SVM gets the best performance and is effective in error analysis of chaotic systems. When real pipeline data is used in the test, the ultimate identification accuracy of HKLS-SVM reaches 97.38% and the position accuracy is 99.28%, indicating that the method proposed in this paper has good performance in detecting and locating small pipeline leaks.

  2. Development of a heterodyne laser interferometer for very small high frequency displacements detection

    International Nuclear Information System (INIS)

    Baarmann, P.

    1992-10-01

    A heterodyne laser interferometer with detection electronics has been developed for measuring very small amplitude high frequency vibrations. A laser beam from HeNe-laser is focused and reflected in the vibrating surface and the generated phase shifts are after interference with a reference beam detected with a photo detector and evaluated in a demodulation system. The set-up is a prototype and techniques to improve the accuracy and sensitivity of the system are presented. The present system can detect vibration amplitude from around 1 Angstrom and is linear up to 250 Angstrom (±4%). Frequencies from a few tens of kHz up to tens of MHz are covered. The low frequency region can be greatly improved. The minimum detectable displacement may be improved by narrowing the bandwidth of the detection system to the region of interest

  3. Modelling job crafting behaviours: Implications for work engagement

    OpenAIRE

    Bakker, Arnold B.; Rodríguez-Muñoz, Alfredo; Sanz Vergel, Ana Isabel

    2016-01-01

    In this study among 206 employees (103 dyads), we followed the job demands–resources approach of job crafting to investigate whether proactively changing one’s work environment influences employee’s (actor’s) own and colleague s (partner’s) work engagement. Using social cognitive theory, we hypothesized that employees would imitate each other’s job crafting behaviours, and therefore influence each other’s work engagement. Results showed that the crafting of social and structural job resources...

  4. 33 CFR 84.24 - High-speed craft.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false High-speed craft. 84.24 Section... RULES ANNEX I: POSITIONING AND TECHNICAL DETAILS OF LIGHTS AND SHAPES § 84.24 High-speed craft. (a) The masthead light of high-speed craft with a length to breadth ratio of less than 3.0 may be placed at a...

  5. Preliminary study of diagnostic workstation with different matrix size for detection of small pulmonary nodules

    International Nuclear Information System (INIS)

    Wu Jie; Wang Xuejian; Wang Bo; Tong Juan; Wei Yuqing; Shen Guiquan; Wang Limei; Cao Jun; Sui He

    2004-01-01

    Objective: To assess the influence in detecting small pulmonary nodules (SPNs) on soft-copy images displayed with different matrix sizes. Methods: Seventy-six chest compute radiographs were selected for the study. Of the 76 test images, 36 pulmonary nodules smaller than 20 mm in diameter were proven by CT, which were further divided into two groups: 1.0-2.0 cm and Z values and standard error of three kinds of view system for individual observers. Results: For 1.0-2.0 cm group, the mean A Z values were 0.7936 for DRCS with 2-fold magnification and window technique, 0.8225 for 1 K monitor with 2-fold magnification and window technique, and 0.8367 for 2 K monitor without magnification; for Z values increased slightly as the display matrix size improved, but there were no significant differences among the three sets in the detection of SPNs in the ROC analyses. Conclusion: It is acceptable to detect small pulmonary nodules of 1.0-2.0 cm in diameter on 1 K monitor and DRCS with magnification. High resolution diagnostic workstation is recommended for detecting small pulmonary nodules <1.0 cm in diameter. Reasonable equipment for the detection of subtle abnormality may result in better cost-efficacy and diagnostic accuracy

  6. Detection of small traumatic hemorrhages using a computer-generated average human brain CT.

    Science.gov (United States)

    Afzali-Hashemi, Liza; Hazewinkel, Marieke; Tjepkema-Cloostermans, Marleen C; van Putten, Michel J A M; Slump, Cornelis H

    2018-04-01

    Computed tomography is a standard diagnostic imaging technique for patients with traumatic brain injury (TBI). A limitation is the poor-to-moderate sensitivity for small traumatic hemorrhages. A pilot study using an automatic method to detect hemorrhages [Formula: see text] in diameter in patients with TBI is presented. We have created an average image from 30 normal noncontrast CT scans that were automatically aligned using deformable image registration as implemented in Elastix software. Subsequently, the average image was aligned to the scans of TBI patients, and the hemorrhages were detected by a voxelwise subtraction of the average image from the CT scans of nine TBI patients. An experienced neuroradiologist and a radiologist in training assessed the presence of hemorrhages in the final images and determined the false positives and false negatives. The 9 CT scans contained 67 small haemorrhages, of which 97% was correctly detected by our system. The neuroradiologist detected three false positives, and the radiologist in training found two false positives. For one patient, our method showed a hemorrhagic contusion that was originally missed. Comparing individual CT scans with a computed average may assist the physicians in detecting small traumatic hemorrhages in patients with TBI.

  7. Small-scale anomaly detection in panoramic imaging using neural models of low-level vision

    Science.gov (United States)

    Casey, Matthew C.; Hickman, Duncan L.; Pavlou, Athanasios; Sadler, James R. E.

    2011-06-01

    Our understanding of sensory processing in animals has reached the stage where we can exploit neurobiological principles in commercial systems. In human vision, one brain structure that offers insight into how we might detect anomalies in real-time imaging is the superior colliculus (SC). The SC is a small structure that rapidly orients our eyes to a movement, sound or touch that it detects, even when the stimulus may be on a small-scale; think of a camouflaged movement or the rustle of leaves. This automatic orientation allows us to prioritize the use of our eyes to raise awareness of a potential threat, such as a predator approaching stealthily. In this paper we describe the application of a neural network model of the SC to the detection of anomalies in panoramic imaging. The neural approach consists of a mosaic of topographic maps that are each trained using competitive Hebbian learning to rapidly detect image features of a pre-defined shape and scale. What makes this approach interesting is the ability of the competition between neurons to automatically filter noise, yet with the capability of generalizing the desired shape and scale. We will present the results of this technique applied to the real-time detection of obscured targets in visible-band panoramic CCTV images. Using background subtraction to highlight potential movement, the technique is able to correctly identify targets which span as little as 3 pixels wide while filtering small-scale noise.

  8. Design and implement of infrared small target real-time detection system based on pipeline technology

    Science.gov (United States)

    Sun, Lihui; Wang, Yongzhong; He, Yongqiang

    2007-01-01

    The detection for motive small target in infrared image sequence has become a hot topic nowadays. Background suppress algorithm based on minim gradient median filter and temporal recursion target detection algorithm are introduced. On the basis of contents previously mentioned, a four stages pipeline structure infrared small target detection process system, which aims at characters of algorithm complexity, large amounts of data to process, high frame frequency and exigent real-time character in this kind of application, is designed and implemented. The logical structure of the system was introduced and the function and signals flows are programmed. The system is composed of two FPGA chips and two DSP chips of TI. According to the function of each part, the system is divided into image preprocess stage, target detection stage, track relation stage and image output stage. The experiment of running algorithms on the system presented in this paper proved that the system could meet acquisition and process of 50Hz 240x320 digital image and the system could real time detect small target with a signal-noise ratio more than 3 reliably. The system achieves the characters of large amount of memory, high real-time processing, excellent extension and favorable interactive interface.

  9. Detection of protein-small molecule binding using a self-referencing external cavity laser biosensor.

    Science.gov (United States)

    Meng Zhang; Peh, Jessie; Hergenrother, Paul J; Cunningham, Brian T

    2014-01-01

    High throughput screening of protein-small molecule binding interactions using label-free optical biosensors is challenging, as the detected signals are often similar in magnitude to experimental noise. Here, we describe a novel self-referencing external cavity laser (ECL) biosensor approach that achieves high resolution and high sensitivity, while eliminating thermal noise with sub-picometer wavelength accuracy. Using the self-referencing ECL biosensor, we demonstrate detection of binding between small molecules and a variety of immobilized protein targets with binding affinities or inhibition constants in the sub-nanomolar to low micromolar range. The demonstrated ability to perform detection in the presence of several interfering compounds opens the potential for increasing the throughput of the approach. As an example application, we performed a "needle-in-the-haystack" screen for inhibitors against carbonic anhydrase isozyme II (CA II), in which known inhibitors are clearly differentiated from inactive molecules within a compound library.

  10. Diverse orientations in craft education: Student teachers’ conceptions and perceptions

    Directory of Open Access Journals (Sweden)

    Tarja Kröger

    2016-03-01

    Full Text Available Craft education in Finland has been in a state of change. The concept of a holistic craft process was implemented in the National Core Curriculum in 2004 and the new Curriculum from 2014 strengthened it. Craft and holistic craft is not one unity but includes several orientations. This study aims to research student teachers’ conceptions and perceptions about diverse orientations and the necessity of craft education before they begin their studies in craft pedagogy. Given that the beliefs that student teachers bring to professional learning play a pivotal role in influencing what they can learn from teacher education, they are a subject worthy of investigation. The data consists of on‐line questionnaire answers by student teachers (N=113 at the University of Finland in teacher education in 2014. The on-line questionnaire was answered at the beginning of a basic course in textile craft education at an early stage of their teacher studies. Findings suggest that student teachers conceive of craft education primarily as model-oriented and skill-oriented rather than design-oriented and expression-oriented. Student teachers think that craft education is needed at school, but explanations are not very diverse. The findings of this study can be useful in the process of developing teacher education programmes.

  11. Which employees craft their jobs and how? Basic dimensions of personality and employees' job crafting behaviour

    NARCIS (Netherlands)

    Bipp, T.; Demerouti, E.

    2015-01-01

    The aim of the current research was to examine to what degree basic personality dimensions serve as determinants of job crafting behaviour and to investigate how this behaviour can be influenced via behavioural intentions. In Study 1, we investigated the relationship of approach and avoidance

  12. Sustainable Innovation of Glass Design and Craft

    DEFF Research Database (Denmark)

    Sparre-Petersen, Maria

    2014-01-01

    , reduction of production and transportation of new glass is desirable (Environmental Protection Agency, 2012), and can be realized by recycling glass, that has already been manufactured, used and collected for recycling, but has ended up in landfills due to the market mechanisms that allow manufacturing...... and deposition of glass is reduced Today glass production predominantly consists of window glass, glass wool for insulation and containers such as bottles and jelly jars. Glass craft and design hold only a fraction of the market. Still there is reason to believe that generation and implementation of new...

  13. Sensitive Detection of Small Particles in Fluids Using Optical Fiber Tip with Dielectrophoresis

    Directory of Open Access Journals (Sweden)

    Yi-Hsin Tai

    2016-02-01

    Full Text Available This work presents using a tapered fiber tip coated with thin metallic film to detect small particles in water with high sensitivity. When an AC voltage applied to the Ti/Al coated fiber tip and indium tin oxide (ITO substrate, a gradient electric field at the fiber tip induced attractive/repulsive force to suspended small particles due to the frequency-dependent dielectrophoresis (DEP effect. Such DEP force greatly enhanced the concentration of the small particles near the tip. The increase of the local concentration also increased the scattering of surface plasmon wave near the fiber tip. Combined both DEP effect and scattering optical near-field, we show the detection limit of the concentration for 1.36 μm polystyrene beads can be down to 1 particle/mL. The detection limit of the Escherichia coli (E. coli bacteria was 20 CFU/mL. The fiber tip sensor takes advantages of ultrasmall volume, label-free and simple detection system.

  14. Crafts and Craft Education as Expressions of Cultural Heritage: Individual Experiences and Collective Values among an International Group of Women University Students

    Science.gov (United States)

    Kokko, Sirpa; Dillon, Patrick

    2011-01-01

    This paper explores relationships between crafts, craft education and cultural heritage as reflected in the individual experiences and collective values of fifteen female university students of different nationalities. The students (all trainee teachers) were following a course in crafts and craft education as part of an International Study…

  15. Mass amplifying probe for sensitive fluorescence anisotropy detection of small molecules in complex biological samples.

    Science.gov (United States)

    Cui, Liang; Zou, Yuan; Lin, Ninghang; Zhu, Zhi; Jenkins, Gareth; Yang, Chaoyong James

    2012-07-03

    Fluorescence anisotropy (FA) is a reliable and excellent choice for fluorescence sensing. One of the key factors influencing the FA value for any molecule is the molar mass of the molecule being measured. As a result, the FA method with functional nucleic acid aptamers has been limited to macromolecules such as proteins and is generally not applicable for the analysis of small molecules because their molecular masses are relatively too small to produce observable FA value changes. We report here a molecular mass amplifying strategy to construct anisotropy aptamer probes for small molecules. The probe is designed in such a way that only when a target molecule binds to the probe does it activate its binding ability to an anisotropy amplifier (a high molecular mass molecule such as protein), thus significantly increasing the molecular mass and FA value of the probe/target complex. Specifically, a mass amplifying probe (MAP) consists of a targeting aptamer domain against a target molecule and molecular mass amplifying aptamer domain for the amplifier protein. The probe is initially rendered inactive by a small blocking strand partially complementary to both target aptamer and amplifier protein aptamer so that the mass amplifying aptamer domain would not bind to the amplifier protein unless the probe has been activated by the target. In this way, we prepared two probes that constitute a target (ATP and cocaine respectively) aptamer, a thrombin (as the mass amplifier) aptamer, and a fluorophore. Both probes worked well against their corresponding small molecule targets, and the detection limits for ATP and cocaine were 0.5 μM and 0.8 μM, respectively. More importantly, because FA is less affected by environmental interferences, ATP in cell media and cocaine in urine were directly detected without any tedious sample pretreatment. Our results established that our molecular mass amplifying strategy can be used to design aptamer probes for rapid, sensitive, and selective

  16. Flying control of small-type helicopter by detecting its in-air natural features

    Directory of Open Access Journals (Sweden)

    Chinthaka Premachandra

    2015-05-01

    Full Text Available Control of a small type helicopter is an interesting research area in unmanned aerial vehicle development. This study aims to detect a more typical helicopter unequipped with markers as a means by which to resolve the various issues of the prior studies. Accordingly, we propose a method of detecting the helicopter location and pose through using an infrastructure camera to recognize its in-air natural features such as ellipse traced by the rotation of the helicopter's propellers. A single-rotor system helicopter was used as the controlled airframe in our experiments. Here, helicopter location is measured by detecting the main rotor ellipse center and pose is measured following relationship between the main rotor ellipse and the tail rotor ellipse. Following these detection results we confirmed the hovering control possibility of the helicopter through experiments.

  17. Design of an Acoustic Target Intrusion Detection System Based on Small-Aperture Microphone Array

    Science.gov (United States)

    Zu, Xingshui; Guo, Feng; Huang, Jingchang; Zhao, Qin; Liu, Huawei; Li, Baoqing; Yuan, Xiaobing

    2017-01-01

    Automated surveillance of remote locations in a wireless sensor network is dominated by the detection algorithm because actual intrusions in such locations are a rare event. Therefore, a detection method with low power consumption is crucial for persistent surveillance to ensure longevity of the sensor networks. A simple and effective two-stage algorithm composed of energy detector (ED) and delay detector (DD) with all its operations in time-domain using small-aperture microphone array (SAMA) is proposed. The algorithm analyzes the quite different velocities between wind noise and sound waves to improve the detection capability of ED in the surveillance area. Experiments in four different fields with three types of vehicles show that the algorithm is robust to wind noise and the probability of detection and false alarm are 96.67% and 2.857%, respectively. PMID:28273838

  18. Small Craft Transportability Design and Certification Process Guidance. Revision B

    Science.gov (United States)

    2010-11-08

    114 114 inches to bottom monorail train LHA 1 2nd Deck 168/109.5 109.5 inches to bottom monorail train LHD 1 2nd Deck 168/109.5 109.5 inches to...bottom monorail train LPD 17 1st Platform (Main-V) 191 150 inches in forward vehicle area 2nd Deck (Upper-V) 133 143.5 inches ramp to flight deck...and crushing. This protection may be as simple as a piece of fire hose that fits over the webbing. Whenever this is necessary, it is preferable

  19. Effects of a job crafting intervention program on work engagement among Japanese employees: a pretest-posttest study.

    Science.gov (United States)

    Sakuraya, Asuka; Shimazu, Akihito; Imamura, Kotaro; Namba, Katsuyuki; Kawakami, Norito

    2016-10-24

    Job crafting, an employee-initiated job design/redesign, has become important for employees' well-being such as work engagement. This study examined the effectiveness of a newly developed job crafting intervention program on work engagement (as primary outcome), as well as job crafting and psychological distress (as secondary outcomes), using a pretest-posttest study design among Japanese employees. Participants were managers of a private company and a private psychiatric hospital in Japan. The job crafting intervention program consisted of two 120-min sessions with a two-week interval between them. Outcomes were assessed at baseline (Time 1), post-intervention (Time 2), and a one-month follow-up (Time 3). The mixed growth model analyses were conducted using time (Time 1, Time 2, and Time 3) as an indicator of intervention effect. Effect sizes were calculated using Cohen's d. The program showed a significant positive effect on work engagement (t = 2.20, p = 0.03) in the mixed growth model analyses, but with only small effect sizes (Cohen's d = 0.33 at Time 2 and 0.26 at Time 3). The program also significantly improved job crafting (t = 2.36, p = 0.02: Cohen's d = 0.36 at Time 2 and 0.47 at Time 3) and reduced psychological distress (t = -2.06, p = 0.04: Cohen's d = -0.15 at Time 2 and -0.31 at Time 3). The study indicated that the newly developed job crafting intervention program was effective in increasing work engagement, as well as in improving job crafting and decreasing psychological distress, among Japanese managers. UMIN Clinical Trials Registry UMIN000024062 . Retrospectively registered 15 September 2016.

  20. Effects of a job crafting intervention program on work engagement among Japanese employees: a pretest-posttest study

    Directory of Open Access Journals (Sweden)

    Asuka Sakuraya

    2016-10-01

    Full Text Available Abstract Background Job crafting, an employee-initiated job design/redesign, has become important for employees’ well-being such as work engagement. This study examined the effectiveness of a newly developed job crafting intervention program on work engagement (as primary outcome, as well as job crafting and psychological distress (as secondary outcomes, using a pretest-posttest study design among Japanese employees. Methods Participants were managers of a private company and a private psychiatric hospital in Japan. The job crafting intervention program consisted of two 120-min sessions with a two-week interval between them. Outcomes were assessed at baseline (Time 1, post-intervention (Time 2, and a one-month follow-up (Time 3. The mixed growth model analyses were conducted using time (Time 1, Time 2, and Time 3 as an indicator of intervention effect. Effect sizes were calculated using Cohen’s d. Results The program showed a significant positive effect on work engagement (t = 2.20, p = 0.03 in the mixed growth model analyses, but with only small effect sizes (Cohen’s d = 0.33 at Time 2 and 0.26 at Time 3. The program also significantly improved job crafting (t = 2.36, p = 0.02: Cohen’s d = 0.36 at Time 2 and 0.47 at Time 3 and reduced psychological distress (t = −2.06, p = 0.04: Cohen’s d = −0.15 at Time 2 and −0.31 at Time 3. Conclusions The study indicated that the newly developed job crafting intervention program was effective in increasing work engagement, as well as in improving job crafting and decreasing psychological distress, among Japanese managers. Trial registration UMIN Clinical Trials Registry UMIN000024062 . Retrospectively registered 15 September 2016.

  1. 33 CFR 149.310 - What are the muster and embarkation requirements for survival craft?

    Science.gov (United States)

    2010-07-01

    ... embarkation requirements for survival craft? 149.310 Section 149.310 Navigation and Navigable Waters COAST... and embarkation requirements for survival craft? Muster and embarkation arrangements for survival craft must comply with 46 CFR 108.540. ...

  2. NATURAL BASES AND ARTISTIC MEANS OF MODERN ARTS AND CRAFTS OF DAGESTAN

    Directory of Open Access Journals (Sweden)

    G. G. Gazimagomedov

    2015-01-01

    Full Text Available The aim is to carry out a generalized analysis of the history of formation of a new artistic language in contemporary arts and crafts of Dagestan. An innovative search for applied artist has gained further development in a series of works of the leading masters of folk arts and crafts of Dagestan. Discussion. For millennia, arts and crafts of Dagestan have been organically linked with the life of people and their everyday way of life and daily activities, with their worldview and understanding of beauty. In the middle of the 1st millennium BC in the mountainous Dagestan, art of bronze casting has reached a high degree of perfection, most vividly represented by statues of different wild and domestic animals. Images of animals are interpreted generically, without study of small details, but with the characteristic features of the exterior. Paired images of birds are often found in the arts and crafts of the medieval Dagestan. This heraldic composition, two-part or in conjunction with the sacred tree - a three-part, presented in metal-plastic and carved stone and wood, was one of the most popular and enduring decorative items that was common during the Middle Ages and has survived to the present day. This also has been further developed and improved and inherited by craftsmen of Dagestan.Conclusion. When creating works of arts and crafts craftsmen use diverse traditional arts and engineering techniques, the ancient but substantially revised and reinterpreted iconic scenes and ornamental motifs. In art, folk craftsmen emphasize the unity of man and nature. Most ornamental motifs common in Dagestan, go back to the very specific nature prototypes. Compositional structure, as the artistic analysis shows, is often borrowed from nature. This feeling becomes a condition for cultural and biological development, acting as a factor of co-evolution of man and nature.

  3. Sensitive detection of a small parathyroid adenoma using fluorocholine PET/CT: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Padinhare-Keloth, Thanseer N. T. K.; Bhadada, Sanjay K.; Sood, Ashwani; Kumar, Rajender; Behera, Arunanshu; Radotra, Bishan D.; Mittal, Bhagwant R. [PGIMER, Chandigarh (India)

    2017-06-15

    Primary hyperparathyroidism is caused by parathyroid adenoma in the majority of cases and diagnosis is usually made biochemically. Pre-surgical localization of parathyroid adenoma is essential to limit the extent of surgery and avoid missing them at ectopic sites. Anatomical and functional imaging are used for the localization, but may fail to identify the small and ectopic parathyroid adenoma. We present a case of small sized ectopic parathyroid adenoma at unusual location detected by F-18 fluorocholine (FCH) PET/CT, where other imaging modalities failed. The post-operative histopathology confirmed the diagnosis of ectopic parathyroid adenoma.

  4. A new method of small target detection based on neural network

    Science.gov (United States)

    Hu, Jing; Hu, Yongli; Lu, Xinxin

    2018-02-01

    The detection and tracking of moving dim target in infrared image have been an research hotspot for many years. The target in each frame of images only occupies several pixels without any shape and structure information. Moreover, infrared small target is often submerged in complicated background with low signal-to-clutter ratio, making the detection very difficult. Different backgrounds exhibit different statistical properties, making it becomes extremely complex to detect the target. If the threshold segmentation is not reasonable, there may be more noise points in the final detection, which is unfavorable for the detection of the trajectory of the target. Single-frame target detection may not be able to obtain the desired target and cause high false alarm rate. We believe the combination of suspicious target detection spatially in each frame and temporal association for target tracking will increase reliability of tracking dim target. The detection of dim target is mainly divided into two parts, In the first part, we adopt bilateral filtering method in background suppression, after the threshold segmentation, the suspicious target in each frame are extracted, then we use LSTM(long short term memory) neural network to predict coordinates of target of the next frame. It is a brand-new method base on the movement characteristic of the target in sequence images which could respond to the changes in the relationship between past and future values of the values. Simulation results demonstrate proposed algorithm can effectively predict the trajectory of the moving small target and work efficiently and robustly with low false alarm.

  5. Detection of Heterogeneous Small Inclusions by a Multi-Step MUSIC Method

    Science.gov (United States)

    Solimene, Raffaele; Dell'Aversano, Angela; Leone, Giovanni

    2014-05-01

    In this contribution the problem of detecting and localizing scatterers with small (in terms of wavelength) cross sections by collecting their scattered field is addressed. The problem is dealt with for a two-dimensional and scalar configuration where the background is given as a two-layered cylindrical medium. More in detail, while scattered field data are taken in the outermost layer, inclusions are embedded within the inner layer. Moreover, the case of heterogeneous inclusions (i.e., having different scattering coefficients) is addressed. As a pertinent applicative context we identify the problem of diagnose concrete pillars in order to detect and locate rebars, ducts and other small in-homogeneities that can populate the interior of the pillar. The nature of inclusions influences the scattering coefficients. For example, the field scattered by rebars is stronger than the one due to ducts. Accordingly, it is expected that the more weakly scattering inclusions can be difficult to be detected as their scattered fields tend to be overwhelmed by those of strong scatterers. In order to circumvent this problem, in this contribution a multi-step MUltiple SIgnal Classification (MUSIC) detection algorithm is adopted [1]. In particular, the first stage aims at detecting rebars. Once rebars have been detected, their positions are exploited to update the Green's function and to subtract the scattered field due to their presence. The procedure is repeated until all the inclusions are detected. The analysis is conducted by numerical experiments for a multi-view/multi-static single-frequency configuration and the synthetic data are generated by a FDTD forward solver. Acknowledgement This work benefited from networking activities carried out within the EU funded COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar." [1] R. Solimene, A. Dell'Aversano and G. Leone, "MUSIC algorithms for rebar detection," J. of Geophysics and Engineering, vol. 10, pp. 1

  6. Mycotoxin profiling of 1000 beer samples with a special focus on craft beer.

    Science.gov (United States)

    Peters, Jeroen; van Dam, Ruud; van Doorn, Ronald; Katerere, David; Berthiller, Franz; Haasnoot, Willem; Nielen, Michel W F

    2017-01-01

    Currently beer is booming, mainly due to the steady rise of craft breweries worldwide. Previous surveys for occurrence of mycotoxins in beer, were mainly focussed on industrial produced beer. The present survey reports the presence of mycotoxins in craft beer and how this compares to industrial produced beer. More than 1000 beers were collected from 47 countries, of which 60% were craft beers. A selection of 1000 samples were screened for the presence of aflatoxin B1, ochratoxin A (OTA), zearalenone (ZEN), fumonisins (FBs), T-2 and HT-2 toxins (T-2 and HT-2) and deoxynivalenol (DON) using a mycotoxin 6-plex immunoassay. For confirmatory analysis, a liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed and applied. The 6-plex screening showed discrepancies with the LC-MS/MS analysis, possibly due to matrix interference and/or the presence of unknown mycotoxin metabolites. The major mycotoxins detected were DON and its plant metabolite deoxynivalenol-3-β-D-glucopyranoside (D3G). The 6-plex immunoassay reported the sum of DON and D3G (DON+D3G) contaminations ranging from 10 to 475 μg/L in 406 beers, of which 73% were craft beers. The popular craft beer style imperial stout, had the highest percentage of samples suspected positive (83%) with 29% of all imperial stout beers having DON+D3G contaminations above 100 μg/L. LC-MS/MS analysis showed that industrial pale lagers from Italy and Spain, predominantly contained FBs (3-69 μg/L). Besides FBs, African traditional beers also contained aflatoxins (0.1-1.2 μg/L). The presence of OTA, T-2, HT-2, ZEN, β-zearalenol, 3/15-acetyl-DON, nivalenol and the conjugated mycotoxin zearalenone 14-sulfate were confirmed in some beers. This study shows that in 27 craft beers, DON+D3G concentrations occurred above (or at) the Tolerable Daily Intake (TDI). Exceeding the TDI, may have a health impact. A better control of brewing malts for craft beer, should be put in place to circumvent this potential problem.

  7. Mycotoxin profiling of 1000 beer samples with a special focus on craft beer.

    Directory of Open Access Journals (Sweden)

    Jeroen Peters

    Full Text Available Currently beer is booming, mainly due to the steady rise of craft breweries worldwide. Previous surveys for occurrence of mycotoxins in beer, were mainly focussed on industrial produced beer. The present survey reports the presence of mycotoxins in craft beer and how this compares to industrial produced beer. More than 1000 beers were collected from 47 countries, of which 60% were craft beers. A selection of 1000 samples were screened for the presence of aflatoxin B1, ochratoxin A (OTA, zearalenone (ZEN, fumonisins (FBs, T-2 and HT-2 toxins (T-2 and HT-2 and deoxynivalenol (DON using a mycotoxin 6-plex immunoassay. For confirmatory analysis, a liquid chromatography tandem mass spectrometry (LC-MS/MS method was developed and applied. The 6-plex screening showed discrepancies with the LC-MS/MS analysis, possibly due to matrix interference and/or the presence of unknown mycotoxin metabolites. The major mycotoxins detected were DON and its plant metabolite deoxynivalenol-3-β-D-glucopyranoside (D3G. The 6-plex immunoassay reported the sum of DON and D3G (DON+D3G contaminations ranging from 10 to 475 μg/L in 406 beers, of which 73% were craft beers. The popular craft beer style imperial stout, had the highest percentage of samples suspected positive (83% with 29% of all imperial stout beers having DON+D3G contaminations above 100 μg/L. LC-MS/MS analysis showed that industrial pale lagers from Italy and Spain, predominantly contained FBs (3-69 μg/L. Besides FBs, African traditional beers also contained aflatoxins (0.1-1.2 μg/L. The presence of OTA, T-2, HT-2, ZEN, β-zearalenol, 3/15-acetyl-DON, nivalenol and the conjugated mycotoxin zearalenone 14-sulfate were confirmed in some beers. This study shows that in 27 craft beers, DON+D3G concentrations occurred above (or at the Tolerable Daily Intake (TDI. Exceeding the TDI, may have a health impact. A better control of brewing malts for craft beer, should be put in place to circumvent this potential

  8. An object-based approach for detecting small brain lesions: application to Virchow-Robin spaces.

    Science.gov (United States)

    Descombes, Xavier; Kruggel, Frithjof; Wollny, Gert; Gertz, Hermann Josef

    2004-02-01

    This paper is concerned with the detection of multiple small brain lesions from magnetic resonance imaging (MRI) data. A model based on the marked point process framework is designed to detect Virchow-Robin spaces (VRSs). These tubular shaped spaces are due to retraction of the brain parenchyma from its supplying arteries. VRS are described by simple geometrical objects that are introduced as small tubular structures. Their radiometric properties are embedded in a data term. A prior model includes interactions describing the clustering property of VRS. A Reversible Jump Markov Chain Monte Carlo algorithm (RJMCMC) optimizes the proposed model, obtained by multiplying the prior and the data model. Example results are shown on T1-weighted MRI datasets of elderly subjects.

  9. Sarawak Bamboo Craft: Symbolism and Phenomenon

    Directory of Open Access Journals (Sweden)

    Arshad Mohd Zaihidee

    2014-04-01

    Full Text Available The relationship between human beings and their environment has stirred reactions between nature and the development of mind and actions that can be discussed using interdisciplinary approaches such as psychology, sociology, anthropology and history, in understanding human thinking and behavior. A psychological approach is intended to evaluate the individual choices and needs in society. A sociological approach details the various patterns in the social organization. An anthropological approach is tied with culture and belief to fulfil human needs which are based on their habitat, while a historical approach looks at the development which is related to the past. Dimensions of experiences, order and logic, selective elaboration and expressions are used to analyze the bamboo craft of Iban, Melanau and Bidayuh societies in Sarawak long-houses. The existence of constitutive, moral, expressive and cognitive symbols has been interpreted based on a theoretical framework that has been developed by Langer Art Theory, Parsons Social Theory and Kaplan Culture Theory. The values and meaning formed are interpreted to understand matters related to the lives of villagers and the finding suggests that bamboo craft expresses the multi-ethnic mind and character in the socio-culture of long- houses in Sarawak.

  10. Detection of high-grade small bowel obstruction on conventional radiography with convolutional neural networks.

    Science.gov (United States)

    Cheng, Phillip M; Tejura, Tapas K; Tran, Khoa N; Whang, Gilbert

    2018-05-01

    The purpose of this pilot study is to determine whether a deep convolutional neural network can be trained with limited image data to detect high-grade small bowel obstruction patterns on supine abdominal radiographs. Grayscale images from 3663 clinical supine abdominal radiographs were categorized into obstructive and non-obstructive categories independently by three abdominal radiologists, and the majority classification was used as ground truth; 74 images were found to be consistent with small bowel obstruction. Images were rescaled and randomized, with 2210 images constituting the training set (39 with small bowel obstruction) and 1453 images constituting the test set (35 with small bowel obstruction). Weight parameters for the final classification layer of the Inception v3 convolutional neural network, previously trained on the 2014 Large Scale Visual Recognition Challenge dataset, were retrained on the training set. After training, the neural network achieved an AUC of 0.84 on the test set (95% CI 0.78-0.89). At the maximum Youden index (sensitivity + specificity-1), the sensitivity of the system for small bowel obstruction is 83.8%, with a specificity of 68.1%. The results demonstrate that transfer learning with convolutional neural networks, even with limited training data, may be used to train a detector for high-grade small bowel obstruction gas patterns on supine radiographs.

  11. Searching the Soul: Veterans and Their Arts and Crafts

    Science.gov (United States)

    Hasio, Cindy

    2011-01-01

    For military veterans suffering from the long-term trauma of warfare, arts and crafts become much more than the fabrication of relics; they can literally save the spirit. Dialogue and interaction between the veterans, volunteers, and staff are crucial to the success of veterans' arts and crafts program. The purpose of this research was threefold.…

  12. Formation control of marine surface craft: a Lagrangian approach

    DEFF Research Database (Denmark)

    Ihle, Ivar-Andre F.; Jouffroy, Jerome; Fossen, Thor I.

    2006-01-01

    This paper presents a method for formation control of marine surface craft inspired by Lagrangian mechanics. The desired formation configuration and response of the marine surface craft are given as a set of constraints in analytical mechanics. Thus, constraints forces arise and feedback from...

  13. Creating Chicago History: Making Outreach Craft Activities Meaningful

    Science.gov (United States)

    Karp, Madeline

    2012-01-01

    When it comes to having a traveling outreach activity for a museum, a craft can seem like the perfect solution. It can seemingly be all things at once--educational, quick and fun. But, if poorly constructed, crafts can also have serious fallbacks. Using the Chicago History Museum and the Millennium Park Family Fun Festival as a case study, this…

  14. Craft Lessons: Teaching Writing K-8. Second Edition

    Science.gov (United States)

    Fletcher, Ralph; Portalupi, JoAnn

    2007-01-01

    Since its publication in 1998 Craft Lessons has become a mainstay of writing teachers, both new and experienced. Practical lessons--each printed on one page--and the instructional language geared to three grade-level groupings: K-2, 3-4, and 5-8 are contained in this book. In the decade since Craft Lessons' publication the world has changed in…

  15. Learning Practices of Femininity through Gendered Craft Education in Finland

    Science.gov (United States)

    Kokko, Sirpa

    2009-01-01

    This paper discusses the processes and practices that link crafts and gender in the upbringing and education of girls. The paper is based on a study conducted among female primary school trainee teachers in Finland. The data are comprised of their experiences with crafts as schoolgirls. The methods of the study were memory work and writing of…

  16. 33 CFR 146.120 - Manning of survival craft.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Manning of survival craft. 146.120 Section 146.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... craft. The owner, the owner's agent, or the person in charge shall assign a person to each life float...

  17. Students' Attitudes towards Craft and Technology in Iceland and Finland

    Science.gov (United States)

    Thorsteinsson, Gísli; Ólafsson, Brynjar; Autio, Ossi

    2012-01-01

    Craft education in both Finland and Iceland originated over 140 years ago and was influenced by the Scandinavian Sloyd pedagogy. Since then, the subject has moved away from craft and towards technology, with the aim being to increase students' technological abilities. In the beginning, the subject largely focused on the students copying artefacts,…

  18. 46 CFR 108.520 - Type of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Type of survival craft. 108.520 Section 108.520 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.520 Type of survival craft. (a) Each lifeboat must be a fire-protected...

  19. Craft-Art as a Basis for Human Activity

    Science.gov (United States)

    Karppinen, Seija

    2008-01-01

    This article based on my doctoral thesis examines the Basic Arts Education system in Finland, focusing on Basic Crafts Education and its description through action concepts. The main task of the study was to create a concept model. In the first part of the study a concept map was created from the practice of Basic Crafts Education. The aim of the…

  20. The comparative risk assessment framework and tools (CRAFT)

    Science.gov (United States)

    Southern Research Station. USDA Forest Service

    2010-01-01

    To help address these challenges, the USDA Forest Service’s Eastern Forest Environmental Threat Assessment Center (EFETAC) and the University of North Carolina Asheville’s National Environmental Modeling and Analysis Center (NEMAC) designed a planning framework, called the Comparative Risk Assessment Framework and Tools (CRAFT). CRAFT is...

  1. Craft Training in Russia: Theory and Practice of Development

    Science.gov (United States)

    Romantsev, Gennadij M.; Efanov, Andrei V.; Moiseev, Andrei V.; Bychkova, Ekaterina Yu.; Karpova, Natalia P.; Tidemann, Bruno

    2016-01-01

    The relevance of the research topic is substantiated by the social commitment to the establishment of a system of craft training focused on training personnel for craft enterprises. The purpose of the article is to provide theoretical and methodological substantiation of the necessity to provide organizational and pedagogical foundations for the…

  2. The detection, causes and repair of the small steam leaks in the PFR evaporator units

    International Nuclear Information System (INIS)

    Smedley, J.A.; Broomfield, A.M.; Anderson, R.

    1984-01-01

    The occurrence of a number of small steam leaks into the gas space above the sodium in the evaporator units of the UKAEA's Prototype Fast Reactor at Dounreay has had a significant impact on plant availability. The paper describes experience with the leak detection system and the phenomena which have caused the leaks and an outline is given of the measures which have been introduced to remedy the problem. (author)

  3. A small azide-modified thiazole-based reporter molecule for fluorescence and mass spectrometric detection

    Directory of Open Access Journals (Sweden)

    Stefanie Wolfram

    2014-10-01

    Full Text Available Molecular probes are widely used tools in chemical biology that allow tracing of bioactive metabolites and selective labeling of proteins and other biomacromolecules. A common structural motif for such probes consists of a reporter that can be attached by copper(I-catalyzed 1,2,3-triazole formation between terminal alkynes and azides to a reactive headgroup. Here we introduce the synthesis and application of the new thiazole-based, azide-tagged reporter 4-(3-azidopropoxy-5-(4-bromophenyl-2-(pyridin-2-ylthiazole for fluorescence, UV and mass spectrometry (MS detection. This small fluorescent reporter bears a bromine functionalization facilitating the automated data mining of electrospray ionization MS runs by monitoring for its characteristic isotope signature. We demonstrate the universal utility of the reporter for the detection of an alkyne-modified small molecule by LC–MS and for the visualization of a model protein by in-gel fluorescence. The novel probe advantageously compares with commercially available azide-modified fluorophores and a brominated one. The ease of synthesis, small size, stability, and the universal detection possibilities make it an ideal reporter for activity-based protein profiling and functional metabolic profiling.

  4. Carbon nanotubes-based chemiresistive immunosensor for small molecules: detection of nitroaromatic explosives.

    Science.gov (United States)

    Park, Miso; Cella, Lakshmi N; Chen, Wilfred; Myung, Nosang V; Mulchandani, Ashok

    2010-12-15

    In recent years, there has been a growing focus on use of one-dimensional (1-D) nanostructures, such as carbon nanotubes and nanowires, as transducer elements for label-free chemiresistive/field-effect transistor biosensors as they provide label-free and high sensitivity detection. While research to-date has elucidated the power of carbon nanotubes- and other 1-D nanostructure-based field effect transistors immunosensors for large charged macromolecules such as proteins and viruses, their application to small uncharged or charged molecules has not been demonstrated. In this paper we report a single-walled carbon nanotubes (SWNTs)-based chemiresistive immunosensor for label-free, rapid, sensitive and selective detection of 2,4,6-trinitrotoluene (TNT), a small molecule. The newly developed immunosensor employed a displacement mode/format in which SWNTs network forming conduction channel of the sensor was first modified with trinitrophenyl (TNP), an analog of TNT, and then ligated with the anti-TNP single chain antibody. Upon exposure to TNT or its derivatives the bound antibodies were displaced producing a large change, several folds higher than the noise, in the resistance/conductance of SWNTs giving excellent limit of detection, sensitivity and selectivity. The sensor detected between 0.5 ppb and 5000 ppb TNT with good selectivity to other nitroaromatic explosives and demonstrated good accuracy for monitoring TNT in untreated environmental water matrix. We believe this new displacement format can be easily generalized to other one-dimensional nanostructure-based chemiresistive immuno/affinity-sensors for detecting small and/or uncharged molecules of interest in environmental monitoring and health care. Copyright © 2010 Elsevier B.V. All rights reserved.

  5. Small sodium-to-gas leak behavior in relation to LMFBR leak detection system design

    International Nuclear Information System (INIS)

    Hopenfeld, J.; Taylor, G.R.; James, L.A.

    1976-01-01

    Various aspects of sodium-to-gas leaks which must be considered in the design of leak detection systems for LMFBR's are discussed. Attention is focused primarily on small, weeping type leaks. Corrosion rates of steels in fused sodium hydroxide and corrosion damage observed at the site of small leaks lead to the conclusion that the sodium-gas reaction products could attack the primary hot leg piping at rates up to 0.08 mils per hour. Based on theoretical considerations of the corrosion mechanism and on visual observations of pipe topography following small sodium leak tests, it is concluded that pipe damage will be manifested by the formation of small detectable leaks prior to the appearance of larger leaks. The case for uniform pipe corrosion along the pipe circumference or along a vertical section of the pipe is also examined. Using a theoretical model for the gravity flow of sodium and reaction products along the pipe surface and a mass transport controlled corrosion process, it is shown that below sodium leak rates of about 30 g/hr for the primary piping corrosion damage will not extend beyond one radius distance from the leak site. A method of estimating the time delay between the initiation of such leaks and the development of a larger leak due to increased pipe stresses resulting from corrosion is presented

  6. Empowering leadership and job crafting: The role of employee optimism.

    Science.gov (United States)

    Thun, Sylvi; Bakker, Arnold B

    2018-06-08

    The objective of this study was to test the relationship between empowering leadership and job crafting and to examine the moderating role of optimism as a personal resource. We hypothesized that the association between empowering leadership and job crafting would be stronger for employees with high (vs. low) levels of optimism. A total of 331 Norwegian workers from a variety of occupations participated in our study. Results of structural equation modelling analysis generally supported our hypotheses. Empowering leadership was positively related to 3 of the 4 job crafting strategies investigated (increasing structural job resources, increasing social job resources, and increasing challenging job demands; but not reducing hindrance job demands). Moreover, as hypothesized, optimism strengthened the empowering leadership-job crafting relationship for increasing structural resources and increasing challenging demands. The results suggest that empowering leadership is an important antecedent of job crafting strategies, except for reducing hindrance demands. The implications of these findings are discussed. Copyright © 2018 John Wiley & Sons, Ltd.

  7. Tensor Fukunaga-Koontz transform for small target detection in infrared images

    Science.gov (United States)

    Liu, Ruiming; Wang, Jingzhuo; Yang, Huizhen; Gong, Chenglong; Zhou, Yuanshen; Liu, Lipeng; Zhang, Zhen; Shen, Shuli

    2016-09-01

    Infrared small targets detection plays a crucial role in warning and tracking systems. Some novel methods based on pattern recognition technology catch much attention from researchers. However, those classic methods must reshape images into vectors with the high dimensionality. Moreover, vectorizing breaks the natural structure and correlations in the image data. Image representation based on tensor treats images as matrices and can hold the natural structure and correlation information. So tensor algorithms have better classification performance than vector algorithms. Fukunaga-Koontz transform is one of classification algorithms and it is a vector version method with the disadvantage of all vector algorithms. In this paper, we first extended the Fukunaga-Koontz transform into its tensor version, tensor Fukunaga-Koontz transform. Then we designed a method based on tensor Fukunaga-Koontz transform for detecting targets and used it to detect small targets in infrared images. The experimental results, comparison through signal-to-clutter, signal-to-clutter gain and background suppression factor, have validated the advantage of the target detection based on the tensor Fukunaga-Koontz transform over that based on the Fukunaga-Koontz transform.

  8. A novel platform based on defect-rich knotted graphene nanotubes for detection of small biomolecules

    International Nuclear Information System (INIS)

    Lan, Shumin; Song, Yingpan; Chen, Qidi; Guo, Zhiyong; Zhan, Hongbing

    2016-01-01

    Highlights: • Curvature of the SC-CNTs’ cavities had more local pressure, leading to form k-GNTs. • k-GNTs are divided into sections by knots with abundant edge-plane sites/defects. • k-GNTs exhibited excellent catalytic activity, sensitivity and reproducibility. - Abstract: Detection of disease-related small biomolecules was of great significance for clinical diagnostics and treatment. In this work, we synthesized defect-rich knotted graphene nanotubes (k-GNTs) via chemical oxidative etching of stacked-up carbon nanotubes (SC-CNTs) followed by chemical reduction, to detect disease-related small biomolecules. We further studied the electrochemical properties using three representative redox probes and analyzed their biosensitivity using five biomolecules. The k-GNT-modified electrodes exhibited excellent electrochemical response, with the lowest ΔE p and the highest k 0 . Besides, the modified electrodes could simultaneously detect and discriminate between dopamine (DA), ascorbic acid and uric acid (UA), as well as differentiate phenethylamine (PEA) and epinephrine (EP) existed in newborn rat serum, providing the wide linear detection ranges with high sensitivities for DA, UA, PEA, and EP. These excellent electrocatalytic properties could be ascribe to the unique knotted graphene nanotube structure with high proportion of defect/edge sites, large, accessible, three-dimensional, accessible surface area, fewer oxygen-containing groups and doped N atoms. Our work reveals defect-rich k-GNTs as a promising platform for further applications in electrochemical biosensing and electrocatalysis.

  9. Small-scale heat detection using catalytic microengines irradiated by laser

    Science.gov (United States)

    Liu, Zhaoqian; Li, Jinxing; Wang, Jiao; Huang, Gaoshan; Liu, Ran; Mei, Yongfeng

    2013-01-01

    We demonstrate a novel approach to modulating the motion speed of catalytic microtubular engines via laser irradiation/heating with regard to small-scale heat detection. Laser irradiation on the engines leads to a thermal heating effect and thus enhances the engine speed. During a laser on/off period, the motion behaviour of a microengine can be repeatable and reversible, demonstrating a regulation of motion speeds triggered by laser illumination. Also, the engine velocity exhibits a linear dependence on laser power in various fuel concentrations, which implies an application potential as local heat sensors. Our work may hold great promise in applications such as lab on a chip, micro/nano factories, and environmental detection.We demonstrate a novel approach to modulating the motion speed of catalytic microtubular engines via laser irradiation/heating with regard to small-scale heat detection. Laser irradiation on the engines leads to a thermal heating effect and thus enhances the engine speed. During a laser on/off period, the motion behaviour of a microengine can be repeatable and reversible, demonstrating a regulation of motion speeds triggered by laser illumination. Also, the engine velocity exhibits a linear dependence on laser power in various fuel concentrations, which implies an application potential as local heat sensors. Our work may hold great promise in applications such as lab on a chip, micro/nano factories, and environmental detection. Electronic supplementary information (ESI) available. See DOI: 10.1039/c2nr32494f

  10. Dim small targets detection based on self-adaptive caliber temporal-spatial filtering

    Science.gov (United States)

    Fan, Xiangsuo; Xu, Zhiyong; Zhang, Jianlin; Huang, Yongmei; Peng, Zhenming

    2017-09-01

    To boost the detect ability of dim small targets, this paper began by using improved anisotropy for background prediction (IABP), followed by target enhancement by improved high-order cumulates (HQS). Finally, on the basis of image pre-processing, to address the problem of missed and wrong detection caused by fixed caliber of traditional pipeline filtering, this paper used targets' multi-frame movement correlation in the time-space domain, combined with the scale-space theory, to propose a temporal-spatial filtering algorithm which allows the caliber to make self-adaptive changes according to the changes of the targets' scale, effectively solving the detection-related issues brought by unchanged caliber and decreased/increased size of the targets. Experiments showed that the improved anisotropic background predication could be loyal to the true background of the original image to the maximum extent, presenting a superior overall performance to other background prediction methods; the improved HQS significantly increased the signal-noise ratio of images; when the signal-noise ratio was lower than 2.6 dB, this detection algorithm could effectively eliminate noise and detect targets. For the algorithm, the lowest signal-to-noise ratio of the detectable target is 0.37.

  11. Low-Altitude and Slow-Speed Small Target Detection Based on Spectrum Zoom Processing

    Directory of Open Access Journals (Sweden)

    Xuwang Zhang

    2018-01-01

    Full Text Available This paper proposes a spectrum zoom processing based target detection algorithm for detecting the weak echo of low-altitude and slow-speed small (LSS targets in heavy ground clutter environments, which can be used to retrofit the existing radar systems. With the existing range-Doppler frequency images, the proposed method firstly concatenates the data from the same Doppler frequency slot of different images and then applies the spectrum zoom processing. After performing the clutter suppression, the target detection can be finally implemented. Through the theoretical analysis and real data verification, it is shown that the proposed algorithm can obtain a preferable spectrum zoom result and improve the signal-to-clutter ratio (SCR with a very low computational load.

  12. Employees’ perceived opportunities to craft and in-role performance : The mediating role of job crafting and work engagement

    NARCIS (Netherlands)

    Van Wingerden, Jessica; Poell, R.F.

    2017-01-01

    The present study was designed to gain knowledge of the relationship between employees' perceived opportunities to craft, their actual job crafting behavior and, in line with JD-R theory, subsequently their work engagement and performance. Although scholars have suggested that employees' perceived

  13. Seismic detection method for small-scale discontinuities based on dictionary learning and sparse representation

    Science.gov (United States)

    Yu, Caixia; Zhao, Jingtao; Wang, Yanfei

    2017-02-01

    Studying small-scale geologic discontinuities, such as faults, cavities and fractures, plays a vital role in analyzing the inner conditions of reservoirs, as these geologic structures and elements can provide storage spaces and migration pathways for petroleum. However, these geologic discontinuities have weak energy and are easily contaminated with noises, and therefore effectively extracting them from seismic data becomes a challenging problem. In this paper, a method for detecting small-scale discontinuities using dictionary learning and sparse representation is proposed that can dig up high-resolution information by sparse coding. A K-SVD (K-means clustering via Singular Value Decomposition) sparse representation model that contains two stage of iteration procedure: sparse coding and dictionary updating, is suggested for mathematically expressing these seismic small-scale discontinuities. Generally, the orthogonal matching pursuit (OMP) algorithm is employed for sparse coding. However, the method can only update one dictionary atom at one time. In order to improve calculation efficiency, a regularized version of OMP algorithm is presented for simultaneously updating a number of atoms at one time. Two numerical experiments demonstrate the validity of the developed method for clarifying and enhancing small-scale discontinuities. The field example of carbonate reservoirs further demonstrates its effectiveness in revealing masked tiny faults and small-scale cavities.

  14. Comparison of hand-craft feature based SVM and CNN based deep learning framework for automatic polyp classification.

    Science.gov (United States)

    Younghak Shin; Balasingham, Ilangko

    2017-07-01

    Colonoscopy is a standard method for screening polyps by highly trained physicians. Miss-detected polyps in colonoscopy are potential risk factor for colorectal cancer. In this study, we investigate an automatic polyp classification framework. We aim to compare two different approaches named hand-craft feature method and convolutional neural network (CNN) based deep learning method. Combined shape and color features are used for hand craft feature extraction and support vector machine (SVM) method is adopted for classification. For CNN approach, three convolution and pooling based deep learning framework is used for classification purpose. The proposed framework is evaluated using three public polyp databases. From the experimental results, we have shown that the CNN based deep learning framework shows better classification performance than the hand-craft feature based methods. It achieves over 90% of classification accuracy, sensitivity, specificity and precision.

  15. Size ratio performance in detecting cerebral aneurysm rupture status is insensitive to small vessel removal.

    Science.gov (United States)

    Lauric, Alexandra; Baharoglu, Merih I; Malek, Adel M

    2013-04-01

    The variable definition of size ratio (SR) for sidewall (SW) vs bifurcation (BIF) aneurysms raises confusion for lesions harboring small branches, such as carotid ophthalmic or posterior communicating locations. These aneurysms are considered SW by many clinicians, but SR methodology classifies them as BIF. To evaluate the effect of ignoring small vessels and SW vs stringent BIF labeling on SR ruptured aneurysm detection performance in borderline aneurysms with small branches, and to reconcile SR-based labeling with clinical SW/BIF classification. Catheter rotational angiographic datasets of 134 consecutive aneurysms (60 ruptured) were automatically measured in 3-dimensional. Stringent BIF labeling was applied to clinically labeled aneurysms, with 21 aneurysms switching label from SW to BIF. Parent vessel size was evaluated both taking into account, and ignoring, small vessels. SR was defined accordingly as the ratio between aneurysm and parent vessel sizes. Univariate and multivariate statistics identified significant features. The square of the correlation coefficient (R(2)) was reported for bivariate analysis of alternative SR calculations. Regardless of SW/BIF labeling method, SR was equally significant in discriminating aneurysm ruptured status (P analysis of alternative SR had a high correlation of R(2) = 0.94 on the whole dataset, and R = 0.98 on the 21 borderline aneurysms. Ignoring small branches from SR calculation maintains rupture status detection performance, while reducing postprocessing complexity and removing labeling ambiguity. Aneurysms adjacent to these vessels can be considered SW for morphometric analysis. It is reasonable to use the clinical SW/BIF labeling when using SR for rupture risk evaluation.

  16. Development of an acoustic wave based biosensor for vapor phase detection of small molecules

    Science.gov (United States)

    Stubbs, Desmond

    For centuries scientific ingenuity and innovation have been influenced by Mother Nature's perfect design. One of her more elusive designs is that of the sensory olfactory system, an array of highly sensitive receptors responsible for chemical vapor recognition. In the animal kingdom this ability is magnified among canines where ppt (parts per trillion) sensitivity values have been reported. Today, detection dogs are considered an essential part of the US drug and explosives detection schemes. However, growing concerns about their susceptibility to extraneous odors have inspired the development of highly sensitive analytical detection tools or biosensors known as "electronic noses". In general, biosensors are distinguished from chemical sensors in that they use an entity of biological origin (e.g. antibody, cell, enzyme) immobilized onto a surface as the chemically-sensitive film on the device. The colloquial view is that the term "biosensors" refers to devices which detect the presence of entities of biological origin, such as proteins or single-stranded DNA and that this detection must take place in a liquid. Our biosensor utilizes biomolecules, specifically IgG monoclonal antibodies, to achieve molecular recognition of relatively small molecules in the vapor phase.

  17. Workflow for the Targeted and Untargeted Detection of Small Metabolites in Fish Skin Mucus

    Directory of Open Access Journals (Sweden)

    Lada Ivanova

    2018-06-01

    Full Text Available The skin mucus of fish is in permanent contact with the aquatic environment. Data from the analysis of the chemical composition of skin mucus could potentially be used for monitoring the health status of the fish. Knowledge about mucus composition or change in composition over time could also contribute to understanding the aetiology of certain diseases. The objective of the present study was the development of a workflow for non-invasive sampling of skin mucus from farmed salmon (Salmo salar for the targeted and untargeted detection of small metabolites. Skin mucus was either scraped off, wiped off using medical wipes, or the mucus’ water phase was absorbed using the same type of medical wipes that was used for the wiping method. Following a simple filtration step, the obtained mucus samples were subjected to hydrophilic interaction chromatography coupled to high-resolution mass spectrometry. Post-acquisition processing included the targeted analysis of 86 small metabolites, of which up to 60 were detected in absorbed mucus. Untargeted analysis of the mucus samples from equally treated salmon revealed that the total variation of the metabolome was lowest in absorbed mucus and highest in the scraped mucus. Thus, future studies including small-molecule metabolomics of skin mucus in fish would benefit from a sampling regime employing absorption of the water phase in order to minimize the bias related to the sampling step. Furthermore, the absorption method is also a less invasive approach allowing for repetitive sampling within short time intervals.

  18. Detected peritoneal fluid in small bowel obstruction is associated with the need for surgical intervention.

    LENUS (Irish Health Repository)

    O'Daly, Brendan J

    2009-06-01

    BACKGROUND: Predicting the clinical course in adhesional small bowel obstruction is difficult. There are no validated clinical or radiologic features that allow early identification of patients likely to require surgical intervention. METHODS: We conducted a retrospective review of 100 patients consecutively admitted to a tertiary level teaching hospital over a 3-year period (2002-2004) who had acute adhesional small bowel obstruction and underwent computed tomography (CT). The primary outcomes that we assessed were conservative management or the need for surgical intervention. We investigated time to physiologic gastrointestinal function recovery as a secondary outcome. We examined independent predictors of surgical intervention in a bivariate analysis using a stepwise logistic regression analysis. RESULTS: Of the 100 patients investigated, we excluded 12. Of the 88 remaining patients, 58 (66%) were managed conservatively and 30 (34%) underwent surgery. Peritoneal fluid detected on a CT scan (n = 37) was associated more frequently with surgery than conservative management (46% v. 29%, p = 0.046, chi(2)). Logistical regression identified peritoneal fluid detected on a CT scan as an independent predictor of surgical intervention (odds ratio 3.0, 95% confidence interval 1.15-7.84). CONCLUSION: The presence of peritoneal fluid on a CT scan in patients with adhesional small bowel obstruction is an independent predictor of surgical intervention and should alert the clinician that the patient is 3 times more likely to require surgery.

  19. Multi-slice spiral CT detects spread of small laryngeal tumors

    International Nuclear Information System (INIS)

    Bruening, R.; Schoepf, U.; Becker, C.; Reiser, M.; Hong, C.; Sturm, C.; Wollenberg, B.

    1999-01-01

    The purpose of the study was to preoperatively investigate small laryngeal carcinomas using multi-slice spiral CT (MSCT) and subsequent multiplanar reconstructions (MPR) and to compare the results to the detailed spread found a surgery and histology. Nine patients with small (T1, T2) laryngeal cancer were investigated on a MSCT scanner (Siemens plus 4 Volume Zoom, Siemens). A 4x1 mm collimation, 120 kV, 200 mAs and a 0.5 seconds rotation time were used, allowing a coverage of the entire larynx in approximately 10 seconds within a single breathhold. Multiplanar reconstruction's (MPR) in sagittal and coronal plane were reconstructed in all patients and rated in consensus reading. In 8 of nine patients, the glottic spread was detected by MSCT, in one case of a supraglottic tumor a glottic invasion was excluded. The infiltration of the anterior commissure, the infiltration into the subglottic space and the extension into the hypo-pharynx was correctly assessed in all patients. MSCT was not able to predict infiltration of the arythnoids in two patients. The use of multi-slice CT for the preoperative assessment of small laryngeal tumors shows great promise. The detection or exclusion of subtle spread of these tumors into the supra- or subglottic space and along the glottic level was possible with high accuracy. As the examination time is short, artifacts are rare and multiplanar reconstructions gain in clinical importance. (orig.) [de

  20. Detection of Sensor Faults in Small Helicopter UAVs Using Observer/Kalman Filter Identification

    Directory of Open Access Journals (Sweden)

    Guillermo Heredia

    2011-01-01

    Full Text Available Reliability is a critical issue in navigation of unmanned aerial vehicles (UAVs since there is no human pilot that can react to any abnormal situation. Due to size and cost limitations, redundant sensor schemes and aeronautical-grade navigation sensors used in large aircrafts cannot be installed in small UAVs. Therefore, other approaches like analytical redundancy should be used to detect faults in navigation sensors and increase reliability. This paper presents a sensor fault detection and diagnosis system for small autonomous helicopters based on analytical redundancy. Fault detection is accomplished by evaluating any significant change in the behaviour of the vehicle with respect to the fault-free behaviour, which is estimated by using an observer. The observer is obtained from input-output experimental data with the Observer/Kalman Filter Identification (OKID method. The OKID method is able to identify the system and an observer with properties similar to a Kalman filter, directly from input-output experimental data. Results are similar to the Kalman filter, but, with the proposed method, there is no need to estimate neither system matrices nor sensor and process noise covariance matrices. The system has been tested with real helicopter flight data, and the results compared with other methods.

  1. Directional support value of Gaussian transformation for infrared small target detection.

    Science.gov (United States)

    Yang, Changcai; Ma, Jiayi; Qi, Shengxiang; Tian, Jinwen; Zheng, Sheng; Tian, Xin

    2015-03-20

    Robust small target detection is one of the key techniques in IR search and tracking systems for self-defense or attacks. In this paper we present a robust solution for small target detection in a single IR image. The key ideas of the proposed method are to use the directional support value of Gaussian transform (DSVoGT) to enhance the targets, and use the multiscale representation provided by DSVoGT to reduce the false alarm rate. The original image is decomposed into sub-bands in different orientations by convolving the image with the directional support value filters, which are deduced from the weighted mapped least-squares-support vector machines (LS-SVMs). Based on the sub-band images, a support value of Gaussian matrix is constructed, and the trace of this matrix is then defined as the target measure. The corresponding multiscale correlations of the target measures are computed for enhancing target signal while suppressing the background clutter. We demonstrate the advantages of the proposed method on real IR images and compare the results against those obtained from standard detection approaches, including the top-hat filter, max-mean filter, max-median filter, min-local-Laplacian of Gaussian (LoG) filter, as well as LS-SVM. The experimental results on various cluttered background images show that the proposed method outperforms other detectors.

  2. The method for detecting small lesions in medical image based on sliding window

    Science.gov (United States)

    Han, Guilai; Jiao, Yuan

    2016-10-01

    At present, the research on computer-aided diagnosis includes the sample image segmentation, extracting visual features, generating the classification model by learning, and according to the model generated to classify and judge the inspected images. However, this method has a large scale of calculation and speed is slow. And because medical images are usually low contrast, when the traditional image segmentation method is applied to the medical image, there is a complete failure. As soon as possible to find the region of interest, improve detection speed, this topic attempts to introduce the current popular visual attention model into small lesions detection. However, Itti model is mainly for natural images. But the effect is not ideal when it is used to medical images which usually are gray images. Especially in the early stages of some cancers, the focus of a disease in the whole image is not the most significant region and sometimes is very difficult to be found. But these lesions are prominent in the local areas. This paper proposes a visual attention mechanism based on sliding window, and use sliding window to calculate the significance of a local area. Combined with the characteristics of the lesion, select the features of gray, entropy, corner and edge to generate a saliency map. Then the significant region is segmented and distinguished. This method reduces the difficulty of image segmentation, and improves the detection accuracy of small lesions, and it has great significance to early discovery, early diagnosis and treatment of cancers.

  3. Ultra-small particles of iron oxide as peroxidase for immunohistochemical detection

    International Nuclear Information System (INIS)

    Wu Yihang; Song Mengjie; Zhang Xiaoqing; Zhang Yu; Wang Chunyu; Gu Ning; Xin Zhuang; Li Suyi

    2011-01-01

    Dimercaptosuccinic acid (DMSA) modified ultra-small particles of iron oxide (USPIO) were synthesized through a two-step process. The first step: oleic acid (OA) capped Fe 3 O 4 (OA-USPIO) were synthesized by a novel oxidation coprecipitation method in H 2 O/DMSO mixing system, where DMSO acts as an oxidant simultaneously. The second step: OA was replaced by DMSA to obtain water-soluble nanoparticles. The as-synthesized nanoparticles were characterized by TEM, FTIR, TGA, VSM, DLS, EDS and UV-vis. Hydrodynamic sizes and Peroxidase-like catalytic activity of the nanoparticles were investigated. The hydrodynamic sizes of the nanoparticles (around 24.4 nm) were well suited to developing stable nanoprobes for bio-detection. The kinetic studies were performed to quantitatively evaluate the catalytic ability of the peroxidase-like nanoparticles. The calculated kinetic parameters indicated that the DMSA-USPIO possesses high catalytic activity. Based on the high activity, immunohistochemical experiments were established: using low-cost nanoparticles as the enzyme instead of expensive HRP, Nimotuzumab was conjugated onto the surface of the nanoparticles to construct a kind of ultra-small nanoprobe which was employed to detect epidermal growth factor receptor (EGFR) over-expressed on the membrane of esophageal cancer cell. The proper sizes of the probes and the result of membranous immunohistochemical staining suggest that the probes can be served as a useful diagnostic reagent for bio-detection.

  4. Aptamer/quantum dot-based simultaneous electrochemical detection of multiple small molecules

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Haixia [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715 (China); Jiang Bingying [School of Chemistry and Chemical Engineering, Chongqing University of Technology, Chongqing 400040 (China); Xiang Yun, E-mail: yunatswu@swu.edu.cn [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715 (China); Zhang Yuyong; Chai Yaqin [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715 (China); Yuan Ruo, E-mail: yuanruo@swu.edu.cn [Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715 (China)

    2011-03-04

    A novel strategy for 'signal on' and sensitive one-spot simultaneous detection of multiple small molecular analytes based on electrochemically encoded barcode quantum dot (QD) tags is described. The target analytes, adenosine triphosphate (ATP) and cocaine, respectively, are sandwiched between the corresponding set of surface-immobilized primary binding aptamers and the secondary binding aptamer/QD bioconjugates. The captured QDs yield distinct electrochemical signatures after acid dissolution, whose position and size reflect the identity and level, respectively, of the corresponding target analytes. Due to the inherent amplification feature of the QD labels and the 'signal on' detection scheme, as well as the sensitive monitoring of the metal ions released upon acid dissolution of the QD labels, low detection limits of 30 nM and 50 nM were obtained for ATP and cocaine, respectively, in our assays. Our multi-analyte sensing system also shows high specificity to target analytes and promising applicability to complex sample matrix, which makes the proposed assay protocol an attractive route for screening of small molecules in clinical diagnosis.

  5. Job crafting: Towards a new model of individual job redesign

    Directory of Open Access Journals (Sweden)

    Maria Tims

    2010-12-01

    Research purpose: The purpose of the study was to fit job crafting in job design theory. Motivation for the study: The study was an attempt to shed more light on the types of proactive behaviours of individual employees at work. Moreover, we explored the concept of job crafting and its antecedents and consequences. Research design, approach and method: A literature study was conducted in which the focus was first on proactive behaviour of the employee and then on job crafting. Main findings: Job crafting can be seen as a specific form of proactive behaviour in which the employee initiates changes in the level of job demands and job resources. Job crafting may be facilitated by job and individual characteristics and may enable employees to fit their jobs to their personal knowledge, skills and abilities on the one hand and to their preferences and needs on the other hand. Practical/managerial implications: Job crafting may be a good way for employees to improve their work motivation and other positive work outcomes. Employees could be encouraged to exert more influence on their job characteristics. Contribution/value-add: This article describes a relatively new perspective on active job redesign by the individual, called job crafting, which has important implications for job design theories.

  6. A novel diagnostic tool for detecting functional patency of the small bowel: the Given patency capsule.

    Science.gov (United States)

    Spada, C; Spera, G; Riccioni, M; Biancone, L; Petruzziello, L; Tringali, A; Familiari, P; Marchese, M; Onder, G; Mutignani, M; Perri, V; Petruzziello, C; Pallone, F; Costamagna, G

    2005-09-01

    The current visualization of small-bowel strictures using traditional radiological methods is associated with high radiation doses and false-negative results. These methods do not always reveal small-bowel patency for solids. The aim is to assess the safety of the Given patency system and its ability to detect intestinal strictures in patients with strictures that are known or suspected radiologically. The Given patency capsule is composed of lactose, remains intact in the gastrointestinal tract for 40-100 hours post ingestion, and disintegrates thereafter. A total of 34 patients with small-bowel stricture were prospectively enrolled; 30 had a previous diagnosis of Crohn's disease, three had adhesion syndrome and in one ischemic enteritis was suspected. Of the patients, 15 (44.1 %) had previously undergone surgery. Following ingestion, the capsule was monitored for integrity and transit time, using a specially designed Given scanner and also radiologically. Seventeen patients had been enrolled with the intent of using the patency capsule as a preliminary test in patients with small-bowel strictures before undergoing video capsule endoscopy. 30 patients (88.2 %) retrieved the capsule in the stool; it was intact in 20 (median transit time 22 hours), and disintegrated in 10 patients (median transit time 53 hours). Six patients complained of abdominal pain which disappeared within 24 hours. The scanner successfully indicated the presence of the capsule in 94 % of cases. Ten patients underwent video capsule endoscopy following the patency capsule examination; in all of these the video capsule passed through the small-bowel stricture. This feasibility study has shown that the Given patency capsule is a safe, effective, and convenient tool for assessment of functional patency of the small bowel. It can indicate functional patency even in cases where traditional radiology indicates stricture.

  7. Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles

    International Nuclear Information System (INIS)

    Bian, Tengfei; Autry, Joseph M.; Casemore, Denise; Li, Ji; Thomas, David D.; He, Gaohong; Xing, Chengguo

    2016-01-01

    We have developed a charge-mediated fusion method to reconstitute the sarco/endoplasmic reticulum Ca 2+ -ATPase (SERCA) in giant unilamellar vesicles (GUV). Intracellular Ca 2+ transport by SERCA controls key processes in human cells such as proliferation, signaling, and contraction. Small-molecule effectors of SERCA are urgently needed as therapeutics for Ca 2+ dysregulation in human diseases including cancer, diabetes, and heart failure. Here we report the development of a method for efficiently reconstituting SERCA in GUV, and we describe a streamlined protocol based on optimized parameters (e.g., lipid components, SERCA preparation, and activity assay requirements). ATP-dependent Ca 2+ transport by SERCA in single GUV was detected directly using confocal fluorescence microscopy with the Ca 2+ indicator Fluo-5F. The GUV reconstitution system was validated for functional screening of Ca 2+ transport using thapsigargin (TG), a small-molecule inhibitor of SERCA currently in clinical trials as a prostate cancer prodrug. The GUV system overcomes the problem of inhibitory Ca 2+ accumulation for SERCA in native and reconstituted small unilamellar vesicles (SUV). We propose that charge-mediated fusion provides a widely-applicable method for GUV reconstitution of clinically-important membrane transport proteins. We conclude that GUV reconstitution is a technological advancement for evaluating small-molecule effectors of SERCA.

  8. Detection of Intermediate-Period Transiting Planets with a Network of Small Telescopes: transitsearch.org

    Science.gov (United States)

    Seagroves, Scott; Harker, Justin; Laughlin, Gregory; Lacy, Justin; Castellano, Tim

    2003-12-01

    We describe a project (transitsearch.org) currently attempting to discover transiting intermediate-period planets orbiting bright parent stars, and we simulate that project's performance. The discovery of such a transit would be an important astronomical advance, bridging the critical gap in understanding between HD 209458b and Jupiter. However, the task is made difficult by intrinsically low transit probabilities and small transit duty cycles. This project's efficient and economical strategy is to photometrically monitor stars that are known (from radial velocity surveys) to bear planets, using a network of widely spaced observers with small telescopes. These observers, each individually capable of precision (1%) differential photometry, monitor candidates during the time windows in which the radial velocity solution predicts a transit if the orbital inclination is close to 90°. We use Monte Carlo techniques to simulate the performance of this network, performing simulations with different configurations of observers in order to optimize coordination of an actual campaign. Our results indicate that transitsearch.org can reliably rule out or detect planetary transits within the current catalog of known planet-bearing stars. A distributed network of skilled amateur astronomers and small college observatories is a cost-effective method for discovering the small number of transiting planets with periods in the range 10 days

  9. Transient small-bowel intussusceptions in adults: significance of ultrasonographic detection

    International Nuclear Information System (INIS)

    Maconi, G.; Radice, E.; Greco, S.; Bezzio, C.; Bianchi Porro, G.

    2007-01-01

    Aim: To investigate the frequency, clinical significance, and outcome of small-bowel intussusceptions in adults detected using ultrasound in an outpatient setting. Patients and methods: In two different retrospective (January 2001 to April 2003) and prospective (May 2003 to June 2005) periods, 33 small-bowel intussusceptions were found in 32 patients (13 females; mean age: 38.1 years) with known or suspected intestinal disease. Patients underwent diagnostic work-up to assess any organic disease. Patients with self-limiting intussusception were submitted to clinical and ultrasonographic follow-up. Results: Of the 32 patients with small-bowel intussusception, 25 were identified in the prospective series of 4487 examinations (0.53%) and seven in the retrospective series of 5342 examinations (0.15%; p = 0.002). Four patients had persistent and 28 self-limiting intussusceptions. Self-limiting intussusceptions were idiopathic in 11 patients (39%) or associated with organic diseases in 17 (Crohn's disease in 11 patients, celiac disease in three, ulcerative colitis in one patient, and previous surgery for cancer in two). Self-limiting intussusceptions were asymptomatic in 25% of patients. Conclusion: Small-bowel intussusceptions in adults are not rare and are frequently self-limiting, idiopathic, or related to organic diseases, mainly Crohn's disease and coeliac disease

  10. Transient small-bowel intussusceptions in adults: significance of ultrasonographic detection

    Energy Technology Data Exchange (ETDEWEB)

    Maconi, G. [Chair of Gastroenterology, Department of Clinical Sciences, L. Sacco University Hospital, Milan (Italy)]. E-mail: giovanni.maconi@unimi.it; Radice, E. [Chair of Gastroenterology, Department of Clinical Sciences, L. Sacco University Hospital, Milan (Italy); Greco, S. [Chair of Gastroenterology, Department of Clinical Sciences, L. Sacco University Hospital, Milan (Italy); Bezzio, C. [Chair of Gastroenterology, Department of Clinical Sciences, L. Sacco University Hospital, Milan (Italy); Bianchi Porro, G. [Chair of Gastroenterology, Department of Clinical Sciences, L. Sacco University Hospital, Milan (Italy)

    2007-08-15

    Aim: To investigate the frequency, clinical significance, and outcome of small-bowel intussusceptions in adults detected using ultrasound in an outpatient setting. Patients and methods: In two different retrospective (January 2001 to April 2003) and prospective (May 2003 to June 2005) periods, 33 small-bowel intussusceptions were found in 32 patients (13 females; mean age: 38.1 years) with known or suspected intestinal disease. Patients underwent diagnostic work-up to assess any organic disease. Patients with self-limiting intussusception were submitted to clinical and ultrasonographic follow-up. Results: Of the 32 patients with small-bowel intussusception, 25 were identified in the prospective series of 4487 examinations (0.53%) and seven in the retrospective series of 5342 examinations (0.15%; p = 0.002). Four patients had persistent and 28 self-limiting intussusceptions. Self-limiting intussusceptions were idiopathic in 11 patients (39%) or associated with organic diseases in 17 (Crohn's disease in 11 patients, celiac disease in three, ulcerative colitis in one patient, and previous surgery for cancer in two). Self-limiting intussusceptions were asymptomatic in 25% of patients. Conclusion: Small-bowel intussusceptions in adults are not rare and are frequently self-limiting, idiopathic, or related to organic diseases, mainly Crohn's disease and coeliac disease.

  11. Incidentally detected small intestine intussusception caused by primary small intenstine carcinoma on {sup 18}F-FDG PET/CT

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyun Jong; Oh, So Won; Kim, Yu Kyeong [Dept. of Nuclear MedicineSeoul Metropolitan Government - Seoul National University Boramae Medical Center, Seoul (Korea, Republic of)

    2017-09-15

    Small intestine intussusception in adults is a rare condition mainly caused by primary or metastatic small intestine malignancy. Here, we present a 72-year-old male patient who was diagnosed with small intestine cancer that was presented as small intestine intussusception on hybrid {sup 18}F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). The patient was initially referred for an abnormality on a chest radiography and severe anemia. FDG PET/CT showed the lung lesion in the right upper lobe of lung as a high FDG uptake mass. Accidentally, FDG PET demonstrated another intense hypermetabolic intraluminal lesion in the small intestine accompanied with intussusception shown as a circumferential hypermetabolic wall. By pathologic examination, the patient was diagnosed as primary small intestine cancer with lung metastasis. This case highlights usefulness of hybrid FDG PET/CT to identify unexpected malignancy.

  12. The methods for detecting multiple small nodules from 3D chest X-ray CT images

    International Nuclear Information System (INIS)

    Hayase, Yosuke; Mekada, Yoshito; Mori, Kensaku; Toriwaki, Jun-ichiro; Natori, Hiroshi

    2004-01-01

    This paper describes a method for detecting small nodules, whose CT values and diameters are more than -600 Hounsfield unit (H.U.) and 2 mm, from three-dimensional chest X-ray CT images. The proposed method roughly consists of two submodules: initial detection of nodule candidates by discriminating between nodule regions and other regions such as blood vessels or bronchi using a shape feature computed from distance values inside the regions and reduction of false positive (FP) regions by using a minimum directional difference filter called minimum directional difference filter (Min-DD) changing its radius suit to the size of the initial candidates. The performance of the proposed method was evaluated by using seven cases of chest X-ray CT images including six abnormal cases where multiple lung cancers are observed. The experimental results for nodules (361 regions in total) showed that sensitivity and FP regions are 71% and 7.4 regions in average per case. (author)

  13. Biochip-Based Detection of KRAS Mutation in Non-Small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Barbara Ziegler

    2011-11-01

    Full Text Available This study is aimed at evaluating the potential of a biochip assay to sensitively detect KRAS mutation in DNA from non-small cell lung cancer (NSCLC tissue samples. The assay covers 10 mutations in codons 12 and 13 of the KRAS gene, and is based on mutant-enriched PCR followed by reverse-hybridization of biotinylated amplification products to an array of sequence-specific probes immobilized on the tip of a rectangular plastic stick (biochip. Biochip hybridization identified 17 (21% samples to carry a KRAS mutation of which 16 (33% were adenocarcinomas and 1 (3% was a squamous cell carcinoma. All mutations were confirmed by DNA sequencing. Using 10 ng of starting DNA, the biochip assay demonstrated a detection limit of 1% mutant sequence in a background of wild-type DNA. Our results suggest that the biochip assay is a sensitive alternative to protocols currently in use for KRAS mutation testing on limited quantity samples.

  14. Detection of small leakage combining dedicated Kalman filters and an extended version of the binary SPRT

    International Nuclear Information System (INIS)

    Racz, A.

    1991-12-01

    A new method is outlined for detection of soft reactor failures. The procedure is applicable when the failure can be described by an additive term (failure vector) in the measurement process of an observable dynamic system. A dedicated Kalman filter generates the innovation process for further testing. The innovation is investigated by a sequential hypothesis testing method. In order to avoid the computational difficulties related to sophisticated multiple hypothesis testing methods, an extended version of Walds's classical binary Sequential Probability Ratio Testing (SPRT) has been developed. The procedure is applied for the problem of (small) leakage detection in the feedwater system of nuclear power plants. Computer simulation results show that the method can recognize less than 1% relative water loss reliably. (author) 10 refs.; 5 figs.; 5 tabs

  15. Guides crafting meaning and identity in a flexible working life

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt

    2017-01-01

    and adding a critical perspective, we understand the guides’ agency, and how they craft scope, tasks and relations in order to sustain a positive self-image and a meaningful working life. Comparing certified guides’ job-crafting practices, we learn that guides are alike across the three countries......Certified guides are exemplary, well-educated, self-employed, casual labourers in a liberal and competitive job market. Applying grounded theory, this exploratory study builds on in-depth qualitative interviews with Danish, Italian and French certified guides. Informed by the theory of job crafting...

  16. On-Chip Spyhole Nanoelectrospray Ionization Mass Spectrometry for Sensitive Biomarker Detection in Small Volumes

    Science.gov (United States)

    Zhong, Xiaoqin; Qiao, Liang; Stauffer, Géraldine; Liu, Baohong; Girault, Hubert H.

    2018-03-01

    A polyimide microfluidic chip with a microhole emitter (Ø 10-12 μm) created on top of a microchannel by scanning laser ablation has been designed for nanoelectrospray ionization (spyhole-nanoESI) to couple microfluidics with mass spectrometry. The spyhole-nanoESI showed higher sensitivity compared to standard ESI and microESI from the end of the microchannel. The limits of detection (LOD) for peptide with the spyhole-nanoESI MS reached 50 pM, which was 600 times lower than that with standard ESI. The present microchip emitter allows the analysis of small volumes of samples. As an example, a small cell lung cancer biomarker, neuron-specific enolase (NSE), was detected by monitoring the transition of its unique peptide with the spyhole-nanoESI MS/MS. NSE at 0.2 nM could be well identified with a signal to noise ratio (S/N) of 50, and thereby its LOD was estimated to be 12 pM. The potential application of the spyhole-nanoESI MS/MS in cancer diagnosis was further demonstrated with the successful detection of 2 nM NSE from 1 μL of human serum. Before the detection, the serum sample spiked with NSE was first depleted with immune spin column, then desalted by centrifugal filter device, and finally digested by trypsin, without any other complicated preparation steps. The concentration matched the real condition of clinical samples. In addition, the microchips can be disposable to avoid any cross contamination. The present technique provides a highly efficient way to couple microfluidics with MS, which brings additional values to various microfluidics and MS-based analysis.

  17. Detection and Segmentation of Small Trees in the Forest-Tundra Ecotone Using Airborne Laser Scanning

    Directory of Open Access Journals (Sweden)

    Marius Hauglin

    2016-05-01

    Full Text Available Due to expected climate change and increased focus on forests as a potential carbon sink, it is of interest to map and monitor even marginal forests where trees exist close to their tolerance limits, such as small pioneer trees in the forest-tundra ecotone. Such small trees might indicate tree line migrations and expansion of the forests into treeless areas. Airborne laser scanning (ALS has been suggested and tested as a tool for this purpose and in the present study a novel procedure for identification and segmentation of small trees is proposed. The study was carried out in the Rollag municipality in southeastern Norway, where ALS data and field measurements of individual trees were acquired. The point density of the ALS data was eight points per m2, and the field tree heights ranged from 0.04 to 6.3 m, with a mean of 1.4 m. The proposed method is based on an allometric model relating field-measured tree height to crown diameter, and another model relating field-measured tree height to ALS-derived height. These models are calibrated with local field data. Using these simple models, every positive above-ground height derived from the ALS data can be related to a crown diameter, and by assuming a circular crown shape, this crown diameter can be extended to a crown segment. Applying this model to all ALS echoes with a positive above-ground height value yields an initial map of possible circular crown segments. The final crown segments were then derived by applying a set of simple rules to this initial “map” of segments. The resulting segments were validated by comparison with field-measured crown segments. Overall, 46% of the field-measured trees were successfully detected. The detection rate increased with tree size. For trees with height >3 m the detection rate was 80%. The relatively large detection errors were partly due to the inherent limitations in the ALS data; a substantial fraction of the smaller trees was hit by no or just a few

  18. A speeded-up saliency region-based contrast detection method for small targets

    Science.gov (United States)

    Li, Zhengjie; Zhang, Haiying; Bai, Jiaojiao; Zhou, Zhongjun; Zheng, Huihuang

    2018-04-01

    To cope with the rapid development of the real applications for infrared small targets, the researchers have tried their best to pursue more robust detection methods. At present, the contrast measure-based method has become a promising research branch. Following the framework, in this paper, a speeded-up contrast measure scheme is proposed based on the saliency detection and density clustering. First, the saliency region is segmented by saliency detection method, and then, the Multi-scale contrast calculation is carried out on it instead of traversing the whole image. Second, the target with a certain "integrity" property in spatial is exploited to distinguish the target from the isolated noises by density clustering. Finally, the targets are detected by a self-adaptation threshold. Compared with time-consuming MPCM (Multiscale Patch Contrast Map), the time cost of the speeded-up version is within a few seconds. Additional, due to the use of "clustering segmentation", the false alarm caused by heavy noises can be restrained to a lower level. The experiments show that our method has a satisfied FASR (False alarm suppression ratio) and real-time performance compared with the state-of-art algorithms no matter in cloudy sky or sea-sky background.

  19. Infrared Small Moving Target Detection via Saliency Histogram and Geometrical Invariability

    Directory of Open Access Journals (Sweden)

    Minjie Wan

    2017-06-01

    Full Text Available In order to detect both bright and dark small moving targets effectively in infrared (IR video sequences, a saliency histogram and geometrical invariability based method is presented in this paper. First, a saliency map that roughly highlights the salient regions of the original image is obtained by tuning its amplitude spectrum in the frequency domain. Then, a saliency histogram is constructed by means of averaging the accumulated saliency value of each gray level in the map, through which bins corresponding to bright target and dark target are assigned with large values in the histogram. Next, single-frame detection of candidate targets is accomplished by a binarized segmentation using an adaptive threshold, and their centroid coordinates with sub-pixel accuracy are calculated through a connected components labeling method as well as a gray-weighted criterion. Finally, considering the motion characteristics in consecutive frames, an inter-frame false alarm suppression method based on geometrical invariability is developed to improve the precision rate further. Quantitative analyses demonstrate the detecting precision of this proposed approach can be up to 97% and Receiver Operating Characteristic (ROC curves further verify our method outperforms other state-of-the-arts methods in both detection rate and false alarm rate.

  20. 47 CFR 80.223 - Special requirements for survival craft stations.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Special requirements for survival craft... requirements for survival craft stations. (a) Survival craft stations capable of transmitting on: (1) 2182 kHz... operate with A3E or A3N emission. (b) Survival craft stations must be able to receive the frequency and...

  1. 46 CFR 117.205 - Survival craft-vessels operating on limited coastwise routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-vessels operating on limited coastwise... PASSENGERS LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 117.205 Survival craft... the survival craft required by §§ 117.204 (a) through (d) of this part, as applicable. (b) Each vessel...

  2. 46 CFR 111.75-16 - Lighting of survival craft and rescue boats.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Lighting of survival craft and rescue boats. 111.75-16... craft and rescue boats. (a) During preparation, launching, and recovery, each survival craft and rescue... of circuits must be such that the lighting for adjacent launching stations for survival craft or...

  3. 46 CFR 108.540 - Survival craft muster and embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 108... OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.540 Survival craft muster and... craft muster station and embarkation station for a survival craft which is boarded before it is launched...

  4. 46 CFR 117.204 - Survival craft-vessels operating on coastwise routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-vessels operating on coastwise routes... PASSENGERS LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 117.204 Survival craft... allowed, the following survival craft requirements apply when not engaged in an overnight voyage: (1...

  5. 46 CFR 117.206 - Survival craft-vessels operating on Great Lakes routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-vessels operating on Great Lakes routes... PASSENGERS LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 117.206 Survival craft... vessel certificated to operate on a Great Lakes route must be provided with the survival craft required...

  6. Detection of Small Colony Variants Among Methicillin-Resistant Staphylococcus aureus Blood Isolates.

    Science.gov (United States)

    Yagci, Server; Sancak, Banu; Hascelik, Gulsen

    2016-12-01

    Staphylococcus aureus small colony variants (SCVs) are associated with chronic and persistent infections. Methicillin-resistant S. aureus (MRSA) SCVs cause more severe infections and mortality rates are higher in comparison with infections caused by MRSA. Our objective was to document the prevalence and phenotypical characteristics of SCVs among MRSA blood isolates. MRSA strains isolated from blood during 1999-2009 were evaluated retrospectively. Among 299 MRSA isolates, suspected colonies were inoculated onto Columbia blood agar and Schaedler agar. Columbia blood agar was incubated in normal atmosphere and Schaedler agar in 5-10% CO 2 , both at 35°C. If the small, nonpigmented, nonhemolytic colonies on Columbia blood agar were seen as normal-sized, hemolytic, and pigmented colonies on Schaedler agar, they were considered as MRSA SCVs. Six MRSA SCVs were detected. When subcultures were made, four of them reversed to phenotypically normal S. aureus, but two isolates were stable as SCV phenotype. The prevalence of SCVs among MRSA blood isolates was found as 6/299 (2%) with 2 (0.67%) stable. The detection of SCVs among MRSA blood isolates was reported from Turkey for the first time in this study. As the clinical significance of MRSA infections is well documented, evaluation of MRSA SCVs in clinical samples, especially from intensive care patients and those who have chronic and persistent infections are important to consider.

  7. Major factors influencing craft productivity in nuclear power plant construction

    International Nuclear Information System (INIS)

    Borcherding, J.D.; Sebastian, S.J.

    1980-01-01

    This paper reports on a research study whose objective was to determine the most influential factors adversely affecting craft productivity in nuclear power plant construction from the perspective of the tradesmen employed at the sites. Data were collected through the use of a questionnaire survey and group interview sessions, predominantly with workmen, at six nuclear power plant construction projects. Craftsmen were chosen as the major data base because of their awareness of how their time would actually be spent on the project. Topics considered include the factors influencing craft productivity, material availability, redoing work, crew interfacing, overcrowded work areas, instruction time, inspection delays, craft turnover, craft absenteeism, foreman changes, foreman incompetence, engineering design lead time, comprehensive scheduling of the design function, the responsibility of the utility, value engineering, plant standardization, the effective utilization of the planning and scheduling system, and the labor-management committee

  8. Construction and Validation of the Perceived Opportunity to Craft Scale.

    Science.gov (United States)

    van Wingerden, Jessica; Niks, Irene M W

    2017-01-01

    We developed and validated a scale to measure employees' perceived opportunity to craft (POC) in two separate studies conducted in the Netherlands (total N = 2329). POC is defined as employees' perception of their opportunity to craft their job. In Study 1, the perceived opportunity to craft scale (POCS) was developed and tested for its factor structure and reliability in an explorative way. Study 2 consisted of confirmatory analyses of the factor structure and reliability of the scale as well as examination of the discriminant and criterion-related validity of the POCS. The results indicated that the scale consists of one dimension and could be reliably measured with five items. Evidence was found for the discriminant validity of the POCS. The scale also showed criterion-related validity when correlated with job crafting (+), job resources (autonomy +; opportunities for professional development +), work engagement (+), and the inactive construct cynicism (-). We discuss the implications of these findings for theory and practice.

  9. The Computer and the Writer's Craft: Implications for Teachers.

    Science.gov (United States)

    Brockmann, R. John; McCauley, Rebecca J.

    1984-01-01

    Examines how computers as a medium for communication affect the craft of writing, and subsequently affect teaching approaches. Discusses the need for teaching online document design and problem-solving processes as they relate to the communication process. (HTH)

  10. 77 FR 22497 - Approval and Promulgation of Air Quality Implementation Plans; Illinois; Small Container...

    Science.gov (United States)

    2012-04-16

    ... Promulgation of Air Quality Implementation Plans; Illinois; Small Container Exemption From VOC Coating Rules... Illinois Administrative Code (Ill. Adm. Code) by adding a ``small container exemption'' for pleasure craft... ``small container exemption'' for pleasure craft surface coating operations. EPA previously approved...

  11. Constructing knowledge through perceptual processes in making craft-art

    Directory of Open Access Journals (Sweden)

    Milla Ojala

    2013-10-01

    Full Text Available The focus of the study is on the knowledge that is constructed through perceptual processes during craft making in the context of the Finnish Basic Education in the Arts (BEA system. Craft studies in the BEA are defined as craft-art. The research method used is the grounded theory. The data consists of seven interviews and participant observations. Participants in the study are adolescents who study craft-art in the BEA system in Visual Art School, Aimo in Hämeenlinna. The aim of the article is to present, define and reflect on the concepts, properties and dimensions concerning perceptual processes that are discovered in this stage of the study following grounded theory procedures. The perceptual processes are an essential means of constructing knowledge in craft-art. Consequently, one aim of the study is to discuss how these processes are connected to various types of knowledge. The perceptual processes are described by seven concepts: imitative, anticipative, evaluative, experimental, emotional, temporal and bodily perceptions. They indicate on a conceptual level the characteristic of knowledge constructed through perceptual processes in craft-art. Further, theconcepts have several properties that can vary dimensionally between two qualities. The properties are activity, function and position. The dimensions of the properties vary from active to passive, formal to informal and internal to external. In conclusion, the concepts can describe a large range of incidents in different situations. They also seem to describe well the practice of  craft-art and there are several connections with pre-existing concepts of knowledge.Keywords: Craft, Knowledge, Perceptual process, Basic Education in the Arts, Grounded Theory 

  12. Craft's brand equity in CZ, focusing on canoeing

    OpenAIRE

    Šťastný, Šimon

    2013-01-01

    Title: Craft's brand equity in CZ, focusing on flat water canoeing. Objectives: The objective of this dissertation is to find out what is the Craft's brand equity and to suggest how to improve it on the Czech market. That would be based on marketing research and supplementary interview. I will be using marketing research and supplementary interview. Methods: In this dissertation the method of electronic questioning was used. The questionnaires were sent by email address after first contact on...

  13. Minimum Plate Thickness in High-Speed Craft

    DEFF Research Database (Denmark)

    Pedersen, Preben Terndrup; Zhang, Shengming

    1998-01-01

    The minimum plate thickness requirements specified by the classification societies for high-speed craft are supposed to ensure adequate resistance to impact loads such as collision with floating objects and objects falling on the deck. The paper presents analytical methods of describing such impact...... phenomena and proposes performance requirements instead of thickness requirements for hull panels in high-speed craft made of different building materials....

  14. Airborne Collision Detection and Avoidance for Small UAS Sense and Avoid Systems

    Science.gov (United States)

    Sahawneh, Laith Rasmi

    The increasing demand to integrate unmanned aircraft systems (UAS) into the national airspace is motivated by the rapid growth of the UAS industry, especially small UAS weighing less than 55 pounds. Their use however has been limited by the Federal Aviation Administration regulations due to collision risk they pose, safety and regulatory concerns. Therefore, before civil aviation authorities can approve routine UAS flight operations, UAS must be equipped with sense-and-avoid technology comparable to the see-and-avoid requirements for manned aircraft. The sense-and-avoid problem includes several important aspects including regulatory and system-level requirements, design specifications and performance standards, intruder detecting and tracking, collision risk assessment, and finally path planning and collision avoidance. In this dissertation, our primary focus is on developing an collision detection, risk assessment and avoidance framework that is computationally affordable and suitable to run on-board small UAS. To begin with, we address the minimum sensing range for the sense-and-avoid (SAA) system. We present an approximate close form analytical solution to compute the minimum sensing range to safely avoid an imminent collision. The approach is then demonstrated using a radar sensor prototype that achieves the required minimum sensing range. In the area of collision risk assessment and collision prediction, we present two approaches to estimate the collision risk of an encounter scenario. The first is a deterministic approach similar to those been developed for Traffic Alert and Collision Avoidance (TCAS) in manned aviation. We extend the approach to account for uncertainties of state estimates by deriving an analytic expression to propagate the error variance using Taylor series approximation. To address unanticipated intruders maneuvers, we propose an innovative probabilistic approach to quantify likely intruder trajectories and estimate the probability of

  15. Automated High-Speed Video Detection of Small-Scale Explosives Testing

    Science.gov (United States)

    Ford, Robert; Guymon, Clint

    2013-06-01

    Small-scale explosives sensitivity test data is used to evaluate hazards of processing, handling, transportation, and storage of energetic materials. Accurate test data is critical to implementation of engineering and administrative controls for personnel safety and asset protection. Operator mischaracterization of reactions during testing contributes to either excessive or inadequate safety protocols. Use of equipment and associated algorithms to aid the operator in reaction determination can significantly reduce operator error. Safety Management Services, Inc. has developed an algorithm to evaluate high-speed video images of sparks from an ESD (Electrostatic Discharge) machine to automatically determine whether or not a reaction has taken place. The algorithm with the high-speed camera is termed GoDetect (patent pending). An operator assisted version for friction and impact testing has also been developed where software is used to quickly process and store video of sensitivity testing. We have used this method for sensitivity testing with multiple pieces of equipment. We present the fundamentals of GoDetect and compare it to other methods used for reaction detection.

  16. On-line detection of small radioactive ions by capillary electrophoresis

    International Nuclear Information System (INIS)

    Klunder, G.L.; Andrews, J.E. Jr.; Russo, R.E.

    1994-01-01

    Worldwide environmental interests have placed a great demand on developing techniques for rapid characterization of contaminated soil and groundwater. Detection of radioactive contaminants is necessary for monitoring effluents from nuclear processes or to assure proper long term storage of radioactive waste. The authors have been investigating the chemistry required to separate representative radioactive small cations and anions by capillary electrophoresis. In order to evaluate the separation chemistry, detection of stable isotopes of the representative ions was achieved by indirect absorption for cations and direct absorption for anions. Several buffer systems which have been considered in the optimization of the separations will be discussed. The authors have designed and tested two on-line radioactivity detectors for capillary electrophoresis. An on-line solid state CdTe detector was constructed for this study and a scintillation detector has been designed using a high gain photodiode light sensor. Different scintillation materials have been tested. Comparison of the detectors, design considerations, efficiency and limits of detection will be presented

  17. Detection of small number of Giardia in biological materials prepared from stray dogs.

    Science.gov (United States)

    Esmailikia, Leila; Ebrahimzade, Elahe; Shayan, Parviz; Amininia, Narges

    2017-12-20

    Giardia lamblia is an intestinal protozoa with intermittent and low shedding especially in dogs, and the detection of Giardia is accompanied with problems such as sampling and diagnostic method. The objective of this study was to detection of Giardia in biological materials with low number of parasite using parasitological and molecular methods, and also to determine whether the examined stray dogs harbor known zoonotic genotype of Giardia. For this aim 85 fecal and duodenal samples were studied from which 1 was positive by Trichrome staining of stool, 4 were positive by staining of duodenal samples. The nested PCR analysis with primers derived from 18 SrRNA showed that the specific PCR product could be amplified in 4 stool and 4 duodenal samples. All positive samples in staining analysis were also positive in nested PCR. No amplification could be observed by nested PCR with primers derived from β giardin gene due to the single copy of gene. Interestingly, the extracted DNA from old fixed stained Giardia positive smears could be also amplified with primers derived from 18SrRNA gene. The sequence analysis of nested PCR products showed that they belong to the genotype D. In conclusion, it is to denote that the Trichrome or Giemsa methods were not suitable for the detection of small number of this parasite in stool and the nested PCR with primers derived from 18S rRNA gene can replace the traditional methods successfully. For detection of Giardia in stool, primers derived from β giardin will not be recommended.

  18. Radiation damage of variscite in historic crafts: Solarization, decolouration, structural changes and spectra from ionoluminescence

    International Nuclear Information System (INIS)

    Garcia-Guinea, J.; Correcher, V.; Sanchez-Munoz, L.; Lopez-Arce, P.; Townsend, P.D.; Hole, D.E.

    2008-01-01

    X-ray diffraction measurements, during halogen lamp illumination to simulate sunlight, (TXRD) show a phase transition from variscite (AlPO 4 .H 2 O) Messbach to variscite Lucin and a loss of the dark green colour. The differential-thermal and thermo-gravimetric (DTA-TG) analyses and thermoluminescence (TL) peaks all depict this first-order phase transition which takes place under sunlight. From the water vaporization temperature up to circa 650 deg. C, a second-order phase transition progressively occurs from variscite to berlinite (AlPO 4 ) by loss of a second unit of water with hydrogen bonded to the lattice. The ion beam luminescence (IBL) spectra of the Zamora variscite display a spectral band from 500 to 570 nm attributed to [UO 2 ] 2+ in phosphates, and another spectral band from 670 to 740 nm is linked with Cr(VI) 3+ defects situated in octahedral Al(VI) 3+ positions. In the hydrous variscite lattice, the Al-O and P-O chemical bonds are mainly covalent; with the degree of covalency of the P-O chemical bond significantly larger than of Al-O. This open structure of variscite, which has a crystal field of reduced strength, involves small shifts of the absorption bands which intensify the blue-green transmission producing the characteristic emerald colour of the dark green variscite of Zamora. These data provide a valuable basis for detection of solarization damage in historic crafts with inlaid variscite in the Museo del Prado (Madrid, Spain)

  19. Postural Stability of Special Warfare Combatant-Craft Crewmen With Tactical Gear.

    Science.gov (United States)

    Morgan, Paul M; Williams, Valerie J; Sell, Timothy C

    The US Naval Special Warfare's Special Warfare Combatant-Craft Crewmen (SWCC) operate on small, high-speed boats while wearing tactical gear (TG). The TG increases mission safety and success but may affect postural stability, potentially increasing risk for musculoskeletal injury. Therefore, the purpose of this study was to examine the effects of TG on postural stability during the Sensory Organization Test (SOT). Eight SWCC performed the SOT on NeuroCom's Balance Manager with TG and with no tactical gear (NTG). The status of gear was performed in randomized order. The SOT consisted of six different conditions that challenge sensory systems responsible for postural stability. Each condition was performed for three trials, resulting in a total of 18 trials. Overall performance, each individual condition, and sensory system analysis (somatosensory, visual, vestibular, preference) were scored. Data were not normally distributed therefore Wilcoxon signed-rank tests were used to compare each variable (ρ = .05). No significant differences were found between NTG and TG tests. No statistically significant differences were detected under the two TG conditions. This may be due to low statistical power, or potentially insensitivity of the assessment. Also, the amount and distribution of weight worn during the TG conditions, and the SWCC's unstable occupational platform, may have contributed to the findings. The data from this sample will be used in future research to better understand how TG affects SWCC. The data show that the addition of TG used in our study did not affect postural stability of SWCC during the SOT. Although no statistically significant differences were observed, there are clinical reasons for continued study of the effect of increased load on postural stability, using more challenging conditions, greater surface perturbations, dynamic tasks, and heavier loads. 2016.

  20. Comparison between air CT and MRI in the detection of small acoustic neurinomas

    Energy Technology Data Exchange (ETDEWEB)

    Kamei, Tetsuya; Nakashima, Aiko; Seto, Hikaru; Kakishita, Masao

    1989-02-01

    Air CT proved useful in yielding images of acoustic tumors as an air filling defect in 11 (24%) of 46 patients. Six of the 11 tumors were small ones of less than 1 cm in diameter. Air CT was also able to exclude an intracanalicular tumor in 29 patients (63%). MRI was performed for comparison in eight patients (nine tumors) already diagnosed by air CT as having an acoustic tumor. MRI detected eight (89%) of nine tumors. A false negative result on MRI was obtained only in one intracanalicular tumor (4.3 mm in size). This was considered to be attributable to limitations of spatial resolution including the wide slice thickness. A protocol for radiological investigation and management of patients whose clinical symptoms and/or audiovestibular examination are highly indicative of acoustic tumor is proposed and discussed. (author).

  1. Comparison between air CT and MRI in the detection of small acoustic neurinomas

    International Nuclear Information System (INIS)

    Kamei, Tetsuya; Nakashima, Aiko; Seto, Hikaru; Kakishita, Masao

    1989-01-01

    Air CT proved useful in yielding images of acoustic tumors as an air filling defect in 11 (24%) of 46 patients. Six of the 11 tumors were small ones of less than 1 cm in diameter. Air CT was also able to exclude an intracanalicular tumor in 29 patients (63%). MRI was performed for comparison in eight patients (nine tumors) already diagnosed by air CT as having an acoustic tumor. MRI detected eight (89%) of nine tumors. A false negative result on MRI was obtained only in one intracanalicular tumor (4.3 mm in size). This was considered to be attributable to limitations of spatial resolution including the wide slice thickness. A protocol for radiological investigation and management of patients whose clinical symptoms and/or audiovestibular examination are highly indicative of acoustic tumor is proposed and discussed. (author)

  2. Studies of Ink Trapping III Direct Detection of Small Air Bubbles in Ink Layer

    Directory of Open Access Journals (Sweden)

    Ikuo Naito

    2006-12-01

    Full Text Available Ink trappings were studied by using polyethylene terephthalate (PET film with black inks for offset proofing and synthetic paper. By observing printed matter from reverse side through the PET film, we detected many air bubbles in the ink layer and between the ink layer and the PET film. They are classified roughly to two groups, small number of large ones (φ = 2 - 5 μm and many small ones (φ = 0.5 - 1.0 μm. The former ones were fixed air bubbles during the trapping. The latter ones decreased according to increase the amount of ink trapped (y. Because number of the air bubbles (Nair bubble increased with increasing the ink distribution time, they seemed to be yielded by suspension of air into the ink layer during ink distribution. By observing printed surface, we also detected many ink peaks (immediately after the trapping and pinholes (at 24 h. The numbers of the ink peaks and pinholes (Nink peak and Npinhole, respectively decreased also with increasing the y value and increased with increasing the ink distribution time. We studied effects of nip width on these values (distribution time = 2 min.; nip width = 2, 3 and 4 mm. The Nair bubble value decreased with increasing nip width contrary to increase the Nink peak and Npinhole values. The effects can be represented by differences in the values of 2 and 4 mm nip widths. At y = 2 gm-2, the difference in the Nair bubble value is about one third (synthetic paper ink or a half (offset proofing ink of the difference in the Nink peak values.

  3. Near-infrared imaging system for detecting small organic foreign substances in foods

    Science.gov (United States)

    Tashima, Hiroto; Genta, Tsuneaki; Ishii, Yuya; Ishiyama, Takeshi; Arai, Shinichi; Fukuda, Mitsuo

    2013-09-01

    Contamination of foodstuffs with foreign substances is a serious problem because it often has negative effects on consumer health. However, detection of small organic substances in foods can be difficult because they are undetectable with traditional inspection apparatus. In this work, we developed new equipment that can detect small organic contaminant substances in food at high speed using a near-infrared (NIR) imaging technique. The absorption spectra of various foods were measured, and the spectra showed low absorbance at wavelengths from 600 nm to 1150 nm. Based on the observable wavelength range of a CMOS camera, which has a high dynamic range, superluminescent diodes (SLDs) with a wavelength of 830 nm were selected as light sources. We arranged 40 SLDs on a flat panel and placed a diffusion panel over them. As a result, uniformly distributed light with an intensity of 0.26 mW/cm2 illuminated an area of 6.0 cm × 6.0 cm. Insects (3 mm wide) and hairs (0.1 mm in diameter) were embedded in stacked ham slices and in chocolate, with a total thickness of 5 mm in each case, and the transmission images were observed. Both insects and hairs were clearly observed as dark shadows with high contrast. We also compensated the images by using software developed in this study to eliminate low spatial frequency components in the images and improve the sharpness and contrast. As a result, the foreign substances were more clearly distinguished in the 5-mm-thick ham.

  4. AN AUTOMATIC DETECTION METHOD FOR EXTREME-ULTRAVIOLET DIMMINGS ASSOCIATED WITH SMALL-SCALE ERUPTION

    Energy Technology Data Exchange (ETDEWEB)

    Alipour, N.; Safari, H. [Department of Physics, University of Zanjan, P.O. Box 45195-313, Zanjan (Iran, Islamic Republic of); Innes, D. E. [Max-Planck Institut fuer Sonnensystemforschung, 37191 Katlenburg-Lindau (Germany)

    2012-02-10

    Small-scale extreme-ultraviolet (EUV) dimming often surrounds sites of energy release in the quiet Sun. This paper describes a method for the automatic detection of these small-scale EUV dimmings using a feature-based classifier. The method is demonstrated using sequences of 171 Angstrom-Sign images taken by the STEREO/Extreme UltraViolet Imager (EUVI) on 2007 June 13 and by Solar Dynamics Observatory/Atmospheric Imaging Assembly on 2010 August 27. The feature identification relies on recognizing structure in sequences of space-time 171 Angstrom-Sign images using the Zernike moments of the images. The Zernike moments space-time slices with events and non-events are distinctive enough to be separated using a support vector machine (SVM) classifier. The SVM is trained using 150 events and 700 non-event space-time slices. We find a total of 1217 events in the EUVI images and 2064 events in the AIA images on the days studied. Most of the events are found between latitudes -35 Degree-Sign and +35 Degree-Sign . The sizes and expansion speeds of central dimming regions are extracted using a region grow algorithm. The histograms of the sizes in both EUVI and AIA follow a steep power law with slope of about -5. The AIA slope extends to smaller sizes before turning over. The mean velocity of 1325 dimming regions seen by AIA is found to be about 14 km s{sup -1}.

  5. CARS detection of liquid-like phase appearance in small mesopores

    Science.gov (United States)

    Arakcheev, Vladimir G.; Bekin, Alexey N.; Morozov, Viacheslav B.

    2017-11-01

    Nonlinear-optical spectroscopic techniques that employ signals from the molecules located inside nanopores have promising potential for investigations of fluid behavior under nanoconfinement. Here, we apply coherent anti-Stokes spectroscopy to investigate the appearance of a liquid-like phase of carbon dioxide in mesoporous Vycor glass under isothermal compression. The spectra of the Q-branch (1388 cm-1) are registered at  -11 °C in a wide pressure range, starting from submonolayer coverage of the pore wall up to the bulk saturation pressure. Results show that a spectral contribution, similar to that of the bulk liquid, appears at relatively low pressure that is several times lower than the capillary-condensation pressure. The Raman shift of the peak is equal to that of the bulk liquid, although the linewidth is somewhat increased. The peak is attributed to the layers adsorbed beyond the monolayer or to small liquid-like clusters appearing in specific areas of the porous network. The spectroscopic approach presented here demonstrates the ability to detect and estimate small amounts of the liquid-like phase and to distinguish it from the layers strongly interacting with the pore surface.

  6. Comparison of monomeric and polymeric horseradish peroxidase as labels in competitive ELISA for small molecule detection

    International Nuclear Information System (INIS)

    Li, Dongyang; Ying, Yibin; Wu, Jian; Niessner, Reinhard; Knopp, Dietmar

    2013-01-01

    We have developed a simple and sensitive competitive enzyme-linked immunosorbent assay (ELISA) to determine aflatoxin B1 (as a model small analyte) and using streptavidin-polymeric horseradish peroxidase complex (SApolyHRP) as a label for signal amplification. The performance of the assay was evaluated by comparing it with the classical indirect competitive ELISA using HRP labeled anti-mouse IgG as the tracer antibody. The results indicate that the SApolyHRP-based competitive ELISA exhibits a typically 2.4-fold steeper slope of the linear working range of the calibration curve compared to the monomeric HRP based classical ELISA, i.e., the sensitivity was increased. The SApolyHRP conjugate causes a typically 19-fold stronger signal generation in comparison to the traditional HRP labeled anti-mouse IgG at the same concentration (25 ng mL −1 ). Moreover, the SApolyHRP-based assay has a much wider linear range and a 3.8-fold better signal-to-noise ratio. Considering its simplicity, sensitivity and ease of operation, this competitive ELISA is considered to be a promising tool for small molecule immuno detection. (author)

  7. Faradaic Impedance Spectroscopy for Detection of Small Molecules Binding using the Avidin-Biotin Model

    International Nuclear Information System (INIS)

    Yoetz-Kopelman, Tal; Ram, Yaron; Freeman, Amihay; Shacham-Diamand, Yosi

    2015-01-01

    The changes in the Faradaic impedance of gold/biomolecules system due to specific binding of small molecule to a significantly larger binding protein molecule were investigated. The biotin (244.31 Da) - avidin (66000 Da) couple was used as a model for small ligand - binding protein biorecognition. The study was carried out under open circuit potential in the presence of [Fe(CN) 6 ] −3/−4 redox couple. An equivalent electrical circuit was proposed and used for the interpretation of the recorded impedance spectra. Adsorption of thiolated avidin increased the electron transfer resistance, R ct , by a factor of about 7.5 while subsequent addition of biotin within the concentration range of 4.1-40.9 nM reduced the value of R ct by amount proportional to the biotin concentration. The addition of biotin did not affect, however, the equivalent double layer capacitance or other equivalent circuit parameters. A simple model based on effective surface coverage by the avidin molecules and the effect of the added biotin on electron transfer through the coated surface is proposed. A model for the minimum detection limit based on the random distribution of the binding protein and its dimensions is proposed

  8. Preliminary Study of Feasibility of Acoustic Detection of Small Sodium-Water Reactions in Lmfbr Steam Generators.

    Energy Technology Data Exchange (ETDEWEB)

    Chamberlain, H. V.

    1970-06-01

    An evaluation of acoustic techniques for the detection of sound resulting from water leaks into liquid sodium was conducted. Acoustic spectra over the range of 100Hz to 80kHz were detected. A leak as small as 0.00008 lb/ sec was detected by the acoustic instrumentation. The indicated leak rate was the smallest that was injected into the liquid sodium, and is not to be interpreted as the smallest leak rate that might be detected by the acoustic method. Detection time was found to be essentially instantaneous.

  9. Detection and genotyping of Chlamydia species responsible for reproductive disorders in Algerian small ruminants.

    Science.gov (United States)

    Merdja, Salah-Eddine; Khaled, Hamza; Aaziz, Rachid; Vorimore, Fabien; Bertin, Claire; Dahmani, Ali; Bouyoucef, Abdallah; Laroucau, Karine

    2015-02-01

    Chlamydiosis in small ruminants is a zoonotic disease mainly related to Chlamydia abortus. This bacterium is responsible for abortions and reproductive disorders in sheep and goats. Stillbirth and infertility, leading to important economic losses, are also associated with this pathology. In Algeria, abortion cases are frequently reported by veterinarians but, except for brucellosis which is a notifiable disease in this country, abortive diseases are in general poorly studied. In order to detect and genotype Chlamydia species in small ruminants in different areas of Algeria, a study was conducted on samples collected from females (164 blood samples and 199 vaginal swabs) between October 2011 and March 2013. Serum samples were tested with a C. abortus-specific indirect ELISA test. Fourteen samples (8.5 %), from six farms (6/20, 30 %) were tested positive. Vaginal swabs were analysed with a real-time PCR targeting all Chlamydiaceae spp. Thirty samples (15 %) were diagnosed positive in 16 farms (16/25, 64 %). Positive samples were all re-tested with a C. abortus- and a C. pecorum-specific real-time PCR. Finally, 13/30 (43.3 %) and 6/30 (20 %) were identified as C. abortus and C. pecorum, respectively. Enough concentrated C. abortus samples were genotyped by multi-loci variable number of tandem repeat (VNTR) analysis (MLVA), and all were related to the genotype [2] group which mainly includes French C. abortus isolates. C. pecorum-positive samples were genotyped by multi-locus sequence typing (MLST). Interestingly, two of them were successfully genotyped and showed identical MLST sequences to VB2, AB10, E58 and SBE, a group which includes C. pecorum isolates considered as highly pathogenic. These findings suggest a possible role of C. abortus and C. pecorum strains in the aetiology of abortion in Algerian small ruminants.

  10. Small, smooth, nonmobile cardiac myxoma detected by transesophageal echocardiography following recurrent cerebral infarction: a case report.

    Science.gov (United States)

    Saito, Yuki; Aizawa, Yoshihiro; Monno, Koyuru; Nagashima, Koichi; Kurokawa, Sayaka; Osaka, Shunji; Akimoto, Takayoshi; Kamei, Satoshi; Tanaka, Masashi; Hirayama, Atsushi

    2017-05-10

    Cardiac myxoma is known to cause repeated events of cerebral embolism. Soft and irregularly shaped myxomas with high mobility are associated with a higher occurrence of cerebral embolism. In contrast, nonmobile cardiac myxomas with a round regular shape are rarely considered to be a cause of cerebral embolism. In this case, we present a patient with recurrent cerebral embolism associated with a small and nonmobile cardiac myxoma of round regular shape. A 76-year-old Japanese man presented to our hospital with weakness in his right upper extremity. He had a history of right frontal lobe infarction in the previous month. T2-weighted magnetic resonance imaging revealed an area of hyperintensity in the left precentral gyrus, indicating acute cerebral infarction. Transthoracic echocardiography revealed normal left ventricular function and no abnormalities. However, transesophageal echocardiography showed a small and nonmobile left atrial tumor with round regular shape attached to the ostium secundum of the atrial septum. Based on these findings, we diagnosed recurrent cerebral infarction due to embolization caused by left atrial myxoma, and cardiac tumor extraction was performed on hospitalization day 36. The excised tumor measured 0.6 × 0.6 × 0.5 cm and was diagnosed as cardiac myxoma by histologic examination. Even small and nonmobile cardiac myxomas with a round regular shape may cause recurrent cerebral infarction. The diagnosis of this type of atrial myxoma is elusive and transesophageal echocardiography was an effective method of detection. In a clinical situation, this type of cardiac myxoma may be overlooked as a cause of cerebral infarction.

  11. Computed tomography to detect body packing: an unusual cause of small bowel obstruction

    International Nuclear Information System (INIS)

    Brown, J.A.; Phang, T.; Enns, R.; Butchart, M.K.; Filipenko, J.D.; Mason, A.C.; Cooperberg, P.I.

    2002-01-01

    Concealment of illicit drugs within the alimentary tract is now an established method used by both smugglers and traffickers to evade detection by authorities. Those who ingest wrapped packets of drugs to transport them across international borders are known as 'body packers,' whereas those who ingest packages of drugs upon an unexpected encounter with law enforcement agents are known as 'body stuffers' or 'quick swallowers. Although most of these individuals require no medical care, acute drug toxicity (from inadvertent leaking of contents or rupture of the drug packet) and bowel obstruction are recognized hazards of drug packet ingestion. The detection of these packets is a challenge to custom officials and police interested in preventing the import and trafficking of illegal drugs, as well as to physicians who have to treat individuals who have ingested them. We report a case of a 38-year-old intravenous drug abuser who presented with an acute small bowel obstruction secondary to an impacted intraluminal heroin balloon in the mid jejunum. The value of computed tomography (CT) in the patient's diagnostic evaluation is highlighted. (author)

  12. Computed tomography to detect body packing: an unusual cause of small bowel obstruction

    Energy Technology Data Exchange (ETDEWEB)

    Brown, J.A. [St. Paul' s Hospital, Dept. of Radiology, Vancouver, British Columbia (Canada); Phang, T. [St. Paul' s Hospital, Dept. of Surgery, Vancouver, British Columbia (Canada); Enns, R. [St. Paul' s Hospital, Div. of Gastroenterology, Dept. of Internal Medicine, Vancouver, British Columbia (Canada); Butchart, M.K. [St. Paul' s Hospital, Dept. of Radiology, Vancouver, British Columbia (Canada); Filipenko, J.D. [St. Paul' s Hospital, Dept. of Pathology, Vancouver, British Columbia (Canada); Mason, A.C.; Cooperberg, P.I. [St. Paul' s Hospital, Dept. of Radiology, Vancouver, British Columbia (Canada)

    2002-04-01

    Concealment of illicit drugs within the alimentary tract is now an established method used by both smugglers and traffickers to evade detection by authorities. Those who ingest wrapped packets of drugs to transport them across international borders are known as 'body packers,' whereas those who ingest packages of drugs upon an unexpected encounter with law enforcement agents are known as 'body stuffers' or 'quick swallowers. Although most of these individuals require no medical care, acute drug toxicity (from inadvertent leaking of contents or rupture of the drug packet) and bowel obstruction are recognized hazards of drug packet ingestion. The detection of these packets is a challenge to custom officials and police interested in preventing the import and trafficking of illegal drugs, as well as to physicians who have to treat individuals who have ingested them. We report a case of a 38-year-old intravenous drug abuser who presented with an acute small bowel obstruction secondary to an impacted intraluminal heroin balloon in the mid jejunum. The value of computed tomography (CT) in the patient's diagnostic evaluation is highlighted. (author)

  13. Insect detection and nitrogen management for irrigated potatoes using remote sensing from small unmanned aircraft systems

    Science.gov (United States)

    Hunt, E. Raymond; Rondon, Silvia I.; Hamm, Philip B.; Turner, Robert W.; Bruce, Alan E.; Brungardt, Josh J.

    2016-05-01

    Remote sensing with small unmanned aircraft systems (sUAS) has potential applications in agriculture because low flight altitudes allow image acquisition at very high spatial resolution. We set up experiments at the Oregon State University Hermiston Agricultural Research and Extension Center with different platforms and sensors to assess advantages and disadvantages of sUAS for precision farming. In 2013, we conducted an experiment with 4 levels of N fertilizer, and followed the changes in the normalized difference vegetation index (NDVI) over time. In late June, there were no differences in chlorophyll content or leaf area index (LAI) among the 3 higher application rates. Consistent with the field data, only plots with the lowest rate of applied N were distinguished by low NDVI. In early August, N deficiency was determined by NDVI, but it was too late to mitigate losses in potato yield and quality. Populations of the Colorado potato beetle (CPB) may rapidly increase, devouring the shoots, thus early detection and treatment could prevent yield losses. In 2014, we conducted an experiment with 4 levels of CPB infestation. Over one day, damage from CPB in some plots increased from 0 to 19%. A visual ranking of damage was not correlated with the total number of CPB or treatment. Plot-scale vegetation indices were not correlated with damage, although the damaged area determined by object-based feature extraction was highly correlated. Methods based on object-based image analysis of sUAS data have potential for early detection and reduced cost.

  14. DETECTION OF AN ULTRA-BRIGHT SUBMILLIMETER GALAXY BEHIND THE SMALL MAGELLANIC CLOUD

    Energy Technology Data Exchange (ETDEWEB)

    Takekoshi, Tatsuya; Minamidani, Tetsuhiro; Sorai, Kazuo; Habe, Asao [Department of Cosmosciences, Graduate School of Science, Hokkaido University, Sapporo 060-0810 (Japan); Tamura, Yoichi; Kohno, Kotaro [Institute of Astronomy, University of Tokyo, Osawa, Mitaka, Tokyo 181-0015 (Japan); Oogi, Taira [Department of Physics, Faculty of Science, Hokkaido University, Sapporo 060-0810 (Japan); Ezawa, Hajime; Komugi, Shinya; Mizuno, Norikazu; Muller, Erik; Kawamura, Akiko [Chile Observatory, National Astronomical Observatory, Mitaka, Tokyo 181-8588 (Japan); Oshima, Tai [Nobeyama Radio Observatory, National Astronomical Observatory of Japan, Minamimaki, Minamisaku, Nagano 384-1305 (Japan); Scott, Kimberly S. [North American ALMA Science Center, National Radio Astronomy Observatory, Charlottesville, VA 22903 (United States); Austermann, Jason E. [Center for Astrophysics and Space Astronomy, University of Colorado, Boulder, CO 80309 (United States); Tosaki, Tomoka [Joetsu University of Education, Joetsu, Niigata 943-8512 (Japan); Onishi, Toshikazu [Department of Physical Science, Osaka Prefecture University, Gakuen 1-1, Sakai, 599-8531 Osaka (Japan); Fukui, Yasuo [Department of Astrophysics, Nagoya University, Chikusa-ku, Nagoya 464-8602 (Japan); Matsuo, Hiroshi [Advanced Technology Center, National Astronomical Observatory of Japan, Mitaka, Tokyo 181-8588 (Japan); Aretxaga, Itziar [Instituto Nacional de Astrofisica, Optica y Electronica (INAOE), 72000 Puebla (Mexico); and others

    2013-09-10

    We report the discovery of a new ultra-bright submillimeter galaxy (SMG) behind the Small Magellanic Cloud (SMC). This SMG is detected as a 43.3 {+-} 8.4 mJy point source (MM J01071-7302, hereafter MMJ0107) in the 1.1 mm continuum survey of the SMC by AzTEC on the ASTE telescope. MMJ0107 is also detected in the radio (843 MHz), Herschel/SPIRE, Spitzer MIPS 24 {mu}m, all IRAC bands, Wide-field Infrared Survey Explorer, and near-infrared (J, H, K{sub S} ). We find an optical (U, B, V) source, which might be the lensing object, at a distance of 1.''4 from near-infrared and IRAC sources. Photometric redshift estimates for the SMG using representative spectral energy distribution templates show the redshifts of 1.4-3.9. We estimate total far-infrared luminosity of (0.3-2.2) Multiplication-Sign 10{sup 14} {mu}{sup -1} L{sub Sun} and a star formation rate of 5600-39, 000 {mu}{sup -1} M{sub Sun} yr{sup -1}, where {mu} is the gravitational magnification factor. This apparent extreme star formation activity is likely explained by a highly magnified gravitational lens system.

  15. Micrometastasis in non-small-cell lung cancer: Detection and staging

    Directory of Open Access Journals (Sweden)

    Gholamreza Mohajeri

    2012-01-01

    Full Text Available Background: The clinical relevance of bone marrow micrometastasis (BMM in non-small-cell lung cancer is undetermined, and the value of such analyses in advanced stage patients has not been clearly assessed previously. This study was conducted to estimate the accuracy of both polymerase chain reaction (PCR and immunohistochemistry (IHC in micrometastases detection and determine the best site for bone marrow biopsy in order to find micrometastasis. Methods: This prospective cross-sectional study was performed in the Department of Thoracic Surgery, Alzahra University Hospital from September 2008 to June 2009. To evaluate the bone marrow, a 3-cm rib segment and an aspirated specimen from the iliac bone prior to tumor resection were taken. PCR and IHC were performed for each specimen to find micrometastasis. Results: Of 41 patients, 14 (34% were positive for BMM by PCR compared with two positive IHC (4.8%. All BMMs were diagnosed in rib segments, and iliac specimens were all free from metastatic lesion. Our data showed no significant association between variables such as age, sex, histology, tumor location, side of tumor, involved lobe, smoking, or weight loss and presence of BMM. Conclusion: PCR could use as a promising method for BMM detection. BMM in a sanctuary site (rib is not associated with advanced stages of lung cancer. In addition, when predictor variables such as age, sex, histology, tumor location, smoking, or weight loss are analyzed, no correlation can be found between micrometastasis prevalence and any of those variables.

  16. Detecting surface runoff location in a small catchment using distributed and simple observation method

    Science.gov (United States)

    Dehotin, Judicaël; Breil, Pascal; Braud, Isabelle; de Lavenne, Alban; Lagouy, Mickaël; Sarrazin, Benoît

    2015-06-01

    Surface runoff is one of the hydrological processes involved in floods, pollution transfer, soil erosion and mudslide. Many models allow the simulation and the mapping of surface runoff and erosion hazards. Field observations of this hydrological process are not common although they are crucial to evaluate surface runoff models and to investigate or assess different kinds of hazards linked to this process. In this study, a simple field monitoring network is implemented to assess the relevance of a surface runoff susceptibility mapping method. The network is based on spatially distributed observations (nine different locations in the catchment) of soil water content and rainfall events. These data are analyzed to determine if surface runoff occurs. Two surface runoff mechanisms are considered: surface runoff by saturation of the soil surface horizon and surface runoff by infiltration excess (also called hortonian runoff). The monitoring strategy includes continuous records of soil surface water content and rainfall with a 5 min time step. Soil infiltration capacity time series are calculated using field soil water content and in situ measurements of soil hydraulic conductivity. Comparison of soil infiltration capacity and rainfall intensity time series allows detecting the occurrence of surface runoff by infiltration-excess. Comparison of surface soil water content with saturated water content values allows detecting the occurrence of surface runoff by saturation of the soil surface horizon. Automatic records were complemented with direct field observations of surface runoff in the experimental catchment after each significant rainfall event. The presented observation method allows the identification of fast and short-lived surface runoff processes at a small spatial and temporal resolution in natural conditions. The results also highlight the relationship between surface runoff and factors usually integrated in surface runoff mapping such as topography, rainfall

  17. A competitive immunoassay for sensitive detection of small molecules chloramphenicol based on luminol functionalized silver nanoprobe.

    Science.gov (United States)

    Yu, Xiuxia; He, Yi; Jiang, Jie; Cui, Hua

    2014-02-17

    Chloramphenicol (CHL) as a broad-spectrum antibiotic has a broad action spectrum against Gram-positive and Gram-negative bacteria, as well as anaerobes. The use of CHL is strictly restricted in poultry because of its toxic effect. However, CHL is still illegally used in animal farming because of its accessibility and low cost. Therefore, sensitive methods are highly desired for the determination of CHL in foodstuffs. The immunoassays based on labeling as an important tool have been reported for the detection of CHL residues in food-producing animals. However, most of the labeling procedures require multi-step reactions and purifications and thus they are complicated and time-consuming. Recently, in our previous work, luminol functionalized silver nanoparticles have been successfully synthesized, which exhibits higher CL efficiency than luminol functionalized gold nanoparticles. In this work, the new luminol functionalized silver nanoparticles have been used for the labeling of small molecules CHL for the first time and a competitive chemiluminescent immunoassay has been developed for the detection of CHL. Owing to the amplification of silver nanoparticles, high sensitivity for CHL could be achieved with a low detection limit of 7.6×10(-9) g mL(-1) and a wide linear dynamic range of 1.0×10(-8)-1.0×10(-6) g mL(-1). This method has also been successfully applied to determine CHL in milk and honey samples with a good recoveries (92% and 102%, 99% and 107% respectively), indicating that the method is feasible for the determination of CHL in real milk and honey samples. The labeling procedure is simple, convenient and fast, superior to previously reported labeling procedures. The immunoassay is also simple, fast, sensitive and selective. It is of application potential for the determination of CHL in foodstuffs. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Scale invariant SURF detector and automatic clustering segmentation for infrared small targets detection

    Science.gov (United States)

    Zhang, Haiying; Bai, Jiaojiao; Li, Zhengjie; Liu, Yan; Liu, Kunhong

    2017-06-01

    The detection and discrimination of infrared small dim targets is a challenge in automatic target recognition (ATR), because there is no salient information of size, shape and texture. Many researchers focus on mining more discriminative information of targets in temporal-spatial. However, such information may not be available with the change of imaging environments, and the targets size and intensity keep changing in different imaging distance. So in this paper, we propose a novel research scheme using density-based clustering and backtracking strategy. In this scheme, the speeded up robust feature (SURF) detector is applied to capture candidate targets in single frame at first. And then, these points are mapped into one frame, so that target traces form a local aggregation pattern. In order to isolate the targets from noises, a newly proposed density-based clustering algorithm, fast search and find of density peak (FSFDP for short), is employed to cluster targets by the spatial intensive distribution. Two important factors of the algorithm, percent and γ , are exploited fully to determine the clustering scale automatically, so as to extract the trace with highest clutter suppression ratio. And at the final step, a backtracking algorithm is designed to detect and discriminate target trace as well as to eliminate clutter. The consistence and continuity of the short-time target trajectory in temporal-spatial is incorporated into the bounding function to speed up the pruning. Compared with several state-of-arts methods, our algorithm is more effective for the dim targets with lower signal-to clutter ratio (SCR). Furthermore, it avoids constructing the candidate target trajectory searching space, so its time complexity is limited to a polynomial level. The extensive experimental results show that it has superior performance in probability of detection (Pd) and false alarm suppressing rate aiming at variety of complex backgrounds.

  19. Detection of small interfering RNA (siRNA) by mass spectrometry procedures in doping controls.

    Science.gov (United States)

    Thomas, Andreas; Walpurgis, Katja; Delahaut, Philippe; Kohler, Maxie; Schänzer, Wilhelm; Thevis, Mario

    2013-01-01

    Uncovering manipulation of athletic performance via small interfering (si)RNA is an emerging field in sports drug testing. Due to the potential to principally knock down every target gene in the organism by means of the RNA interference pathway, this facet of gene doping has become a realistic scenario. In the present study, two distinct model siRNAs comprising 21 nucleotides were designed as double strands which were perfect counterparts to a sequence of the respective messenger RNA coding the muscle regulator myostatin of Rattus norvegicus. Several modified nucleotides were introduced in both the sense and the antisense strand comprising phosphothioates, 2'-O-methylation, 2'-fluoro-nucleotides, locked nucleic acids and a cholesterol tag at the 3'-end. The model siRNAs were applied to rats at 1 mg/kg (i.v.) and blood as well as urine samples were collected. After isolation of the RNA by means of a RNA purification kit, the target analytes were detected by liquid chromatography - high resolution/high accuracy mass spectrometry (LC-HRMS). Analytes were detected as modified nucleotides after alkaline hydrolysis, as intact oligonucleotide strands (top-down) and by means of denaturing SDS-PAGE analysis. The gel-separated siRNA was further subjected to in-gel hydrolysis with different RNases and subsequent identification of the fragments by untargeted LC-HRMS analysis (bottom-up, 'experimental RNomics'). Combining the results of all approaches, the identification of several 3'-truncated urinary metabolites was accomplished and target analytes were detected up to 24 h after a single administration. Simultaneously collected blood samples yielded no promising results. The methods were validated and found fit-for-purpose for doping controls. Copyright © 2013 John Wiley & Sons, Ltd.

  20. Teaching Quantum Mechanics with qCraft: Outreach and Video Games

    Science.gov (United States)

    Kubica, Aleksander; Chatwin-Davies, Aidan; Michalakis, Spyridon

    Why is quantum mechanics considered a hard and inaccessible subject? Part of the difficulty is due to the nature of the subject itself. However, no small part of the difficulty is its pedagogy, which often relies on out-of-date historical motivation and experimental evidence that is disconnected from day-to-day experiences. In this first talk, we explore ways in which video games are well-suited to teaching quantum mechanics, in particular with regards to building intuition, as well as some of their limitations. We then illustrate these considerations through qCraft, an extension for Minecraft that incorporates aspects of quantum mechanics into the game.

  1. Small nodule detectability evaluation using a generalized scan-statistic model

    International Nuclear Information System (INIS)

    Popescu, Lucretiu M; Lewitt, Robert M

    2006-01-01

    In this paper is investigated the use of the scan statistic for evaluating the detectability of small nodules in medical images. The scan-statistic method is often used in applications in which random fields must be searched for abnormal local features. Several results of the detection with localization theory are reviewed and a generalization is presented using the noise nodule distribution obtained by scanning arbitrary areas. One benefit of the noise nodule model is that it enables determination of the scan-statistic distribution by using only a few image samples in a way suitable both for simulation and experimental setups. Also, based on the noise nodule model, the case of multiple targets per image is addressed and an image abnormality test using the likelihood ratio and an alternative test using multiple decision thresholds are derived. The results obtained reveal that in the case of low contrast nodules or multiple nodules the usual test strategy based on a single decision threshold underperforms compared with the alternative tests. That is a consequence of the fact that not only the contrast or the size, but also the number of suspicious nodules is a clue indicating the image abnormality. In the case of the likelihood ratio test, the multiple clues are unified in a single decision variable. Other tests that process multiple clues differently do not necessarily produce a unique ROC curve, as shown in examples using a test involving two decision thresholds. We present examples with two-dimensional time-of-flight (TOF) and non-TOF PET image sets analysed using the scan statistic for different search areas, as well as the fixed position observer

  2. Small-scale Scheimpflug lidar for aerosol extinction coefficient and vertical atmospheric transmittance detection.

    Science.gov (United States)

    Sun, Guodong; Qin, Laian; Hou, Zaihong; Jing, Xu; He, Feng; Tan, Fengfu; Zhang, Silong

    2018-03-19

    In this paper, a new prototypical Scheimpflug lidar capable of detecting the aerosol extinction coefficient and vertical atmospheric transmittance at 1 km above the ground is described. The lidar system operates at 532 nm and can be used to detect aerosol extinction coefficients throughout an entire day. Then, the vertical atmospheric transmittance can be determined from the extinction coefficients with the equation of numerical integration in this area. CCD flat fielding of the image data is used to mitigate the effects of pixel sensitivity variation. An efficient method of two-dimensional wavelet transform according to a local threshold value has been proposed to reduce the Gaussian white noise in the lidar signal. Furthermore, a new iteration method of backscattering ratio based on genetic algorithm is presented to calculate the aerosol extinction coefficient and vertical atmospheric transmittance. Some simulations are performed to reduce the different levels of noise in the simulated signal in order to test the precision of the de-noising method and inversion algorithm. The simulation result shows that the root-mean-square errors of extinction coefficients are all less than 0.02 km -1 , and that the relative errors of the atmospheric transmittance between the model and inversion data are below 0.56% for all cases. The feasibility of the instrument and the inversion algorithm have also been verified by an optical experiment. The average relative errors of aerosol extinction coefficients between the Scheimpflug lidar and the conventional backscattering elastic lidar are 3.54% and 2.79% in the full overlap heights of two time points, respectively. This work opens up new possibilities of using a small-scale Scheimpflug lidar system for the remote sensing of atmospheric aerosols.

  3. Detail in architecture: Between arts & crafts

    Science.gov (United States)

    Dulencin, Juraj

    2016-06-01

    Architectural detail represents an important part of architecture. Not only can it be used as an identifier of a specific building but at the same time enhances the experience of the realized project. Within it lie the signs of a great architect and clues to understanding his or her way of thinking. It is therefore the central topic of a seminar offered to architecture students at the Brno University of Technology. During the course of the semester-long class the students acquaint themselves with atypical architectural details of domestic and international architects by learning to read them, understand them and subsequently draw them by creating architectural blueprints. In other words, by general analysis of a detail the students learn theoretical thinking of its architect who, depending on the nature of the design, had to incorporate a variety of techniques and crafts. Students apply this analytical part to their own architectural detail design. The methodology of the seminar consists of experiential learning by project management and is complemented by a series of lectures discussing a diversity of details as well as materials and technologies required to implement it. The architectural detail design is also part of students' bachelors thesis, therefore, the realistic nature of their blueprints can be verified in the production process of its physical counterpart. Based on their own documentation the students choose the most suitable manufacturing process whether it is supplied by a specific technology or a craftsman. Students actively participate in the production and correct their design proposals in real scale with the actual material. A student, as a future architect, stands somewhere between a client and an artisan, materializes his or her idea and adjusts the manufacturing process so that the final detail fulfills aesthetic consistency and is in harmony with its initial concept. One of the very important aspects of the design is its economic cost, an

  4. Experimental Investigation of a Wing-in-Ground Effect Craft

    Directory of Open Access Journals (Sweden)

    M. Mobassher Tofa

    2014-01-01

    Full Text Available The aerodynamic characteristics of the wing-in-ground effect (WIG craft model that has a noble configuration of a compound wing was experimentally investigated and Universiti Teknologi Malaysia (UTM wind tunnel with and without endplates. Lift and drag forces, pitching moment coefficients, and the centre of pressure were measured with respect to the ground clearance and the wing angle of attack. The ground effect and the existence of the endplates increase the wing lift-to-drag ratio at low ground clearance. The results of this research work show new proposed design of the WIG craft with compound wing and endplates, which can clearly increase the aerodynamic efficiency without compromising the longitudinal stability. The use of WIG craft is representing an ambitious technology that will help in reducing time, effort, and money of the conventional marine transportation in the future.

  5. Experimental investigation of a wing-in-ground effect craft.

    Science.gov (United States)

    Tofa, M Mobassher; Maimun, Adi; Ahmed, Yasser M; Jamei, Saeed; Priyanto, Agoes; Rahimuddin

    2014-01-01

    The aerodynamic characteristics of the wing-in-ground effect (WIG) craft model that has a noble configuration of a compound wing was experimentally investigated and Universiti Teknologi Malaysia (UTM) wind tunnel with and without endplates. Lift and drag forces, pitching moment coefficients, and the centre of pressure were measured with respect to the ground clearance and the wing angle of attack. The ground effect and the existence of the endplates increase the wing lift-to-drag ratio at low ground clearance. The results of this research work show new proposed design of the WIG craft with compound wing and endplates, which can clearly increase the aerodynamic efficiency without compromising the longitudinal stability. The use of WIG craft is representing an ambitious technology that will help in reducing time, effort, and money of the conventional marine transportation in the future.

  6. Reaction-based small-molecule fluorescent probes for dynamic detection of ROS and transient redox changes in living cells and small animals.

    Science.gov (United States)

    Lü, Rui

    2017-09-01

    Dynamic detection of transient redox changes in living cells and animals has broad implications for human health and disease diagnosis, because intracellular redox homeostasis regulated by reactive oxygen species (ROS) plays important role in cell functions, normal physiological functions and some serious human diseases (e.g., cancer, Alzheimer's disease, diabetes, etc.) usually have close relationship with the intracellular redox status. Small-molecule ROS-responsive fluorescent probes can act as powerful tools for dynamic detection of ROS and redox changes in living cells and animals through fluorescence imaging techniques; and great advances have been achieved recently in the design and synthesis of small-molecule ROS-responsive fluorescent probes. This article highlights up-to-date achievements in designing and using the reaction-based small-molecule fluorescent probes (with high sensitivity and selectivity to ROS and redox cycles) in the dynamic detection of ROS and transient redox changes in living cells and animals through fluorescence imaging. Copyright © 2017. Published by Elsevier Ltd.

  7. Innovative Design of a Laparoscopic Probe for Non-Invasive Intraoperative Detection of Small Endoluminal Digestive Tumours

    Directory of Open Access Journals (Sweden)

    Bogdan Mocan

    2015-12-01

    Full Text Available The present paper highlights the design methodology, the prototype development and the ex-vivo testing of a sensing laparoscopic probe that could be used by surgeons and by surgeon’s assistive robotic systems for detection of small endoluminal digestive tumours. The proposed design framework guides the decision-makers towards a superior balance between quality, efficiency and surgical procedure issues in medical instruments development. A prototype of the sensitive laparoscopic probe for non-invasive intraoperative detection of small endoluminal digestive tumours was developed. The prototype was tested in ex-vivo experimental conditions – open and laparoscopic surgery. The results reveals that the developed prototype is easy to use, adequate and efficient in precise detection of small endoluminal digestive tumours in-between 60÷85% of cases.

  8. DEWS (DEep White matter hyperintensity Segmentation framework): A fully automated pipeline for detecting small deep white matter hyperintensities in migraineurs.

    Science.gov (United States)

    Park, Bo-Yong; Lee, Mi Ji; Lee, Seung-Hak; Cha, Jihoon; Chung, Chin-Sang; Kim, Sung Tae; Park, Hyunjin

    2018-01-01

    Migraineurs show an increased load of white matter hyperintensities (WMHs) and more rapid deep WMH progression. Previous methods for WMH segmentation have limited efficacy to detect small deep WMHs. We developed a new fully automated detection pipeline, DEWS (DEep White matter hyperintensity Segmentation framework), for small and superficially-located deep WMHs. A total of 148 non-elderly subjects with migraine were included in this study. The pipeline consists of three components: 1) white matter (WM) extraction, 2) WMH detection, and 3) false positive reduction. In WM extraction, we adjusted the WM mask to re-assign misclassified WMHs back to WM using many sequential low-level image processing steps. In WMH detection, the potential WMH clusters were detected using an intensity based threshold and region growing approach. For false positive reduction, the detected WMH clusters were classified into final WMHs and non-WMHs using the random forest (RF) classifier. Size, texture, and multi-scale deep features were used to train the RF classifier. DEWS successfully detected small deep WMHs with a high positive predictive value (PPV) of 0.98 and true positive rate (TPR) of 0.70 in the training and test sets. Similar performance of PPV (0.96) and TPR (0.68) was attained in the validation set. DEWS showed a superior performance in comparison with other methods. Our proposed pipeline is freely available online to help the research community in quantifying deep WMHs in non-elderly adults.

  9. Detection of lymphangiogenesis in non-small cell lung cancer and its prognostic value

    Directory of Open Access Journals (Sweden)

    Liao Rong-xia

    2009-02-01

    Full Text Available Abstract Background Our aim was to detect lymphatic endothelial marker podoplanin, lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1 and vascular endothelial growth factor receptor-3 (VEGFR-3 and study the prognostic relevance of lymphangiogenesis in non-small cell lung cancer (NSCLC. Materials 82 paraffin-embedded tissues and 40 fresh frozen tissues from patients with NSCLC were studied. Tumor samples were immunostained for the lymphatic endothelial markers. Lymphangiogenesis was assessed by immunohistochemical double stains for Podoplanin and Ki-67. The prognostic relevance of lymphangiogenesis-related clinicopathological parameters in NSCLC was evaluated. Results We found that the number of podoplanin positive vessels was correlated positively with the number of LYVE-1 positive vessels. Most of VEGFR-3 positive, few of LYVE-1 positive and none of podoplanin positive vessels were blood vessels. Peritumoral lymphatic vessel density (ptLVD, pathologic stage, lymph node status, lymphatic vessel invasion (LVI, vascular endothelial growth factor-C (VEGF-C expression and Ki-67 index of the endothelium cells of the micro lymphatic vessels (Ki67% were associated significantly with a higher risk of tumor progress. ptLVD, pathologic stage, lymph-node metastasis and Ki67% were independent prognostic parameters for overall survival. Conclusion Podoplanin positive ptLVD might play important roles in the lymphangiogenesis and progression of NSCLC. Patients with high podoplanin+ ptLVD have a poor prognosis.

  10. Selection of optimal multispectral imaging system parameters for small joint arthritis detection

    Science.gov (United States)

    Dolenec, Rok; Laistler, Elmar; Stergar, Jost; Milanic, Matija

    2018-02-01

    Early detection and treatment of arthritis is essential for a successful outcome of the treatment, but it has proven to be very challenging with existing diagnostic methods. Novel methods based on the optical imaging of the affected joints are becoming an attractive alternative. A non-contact multispectral imaging (MSI) system for imaging of small joints of human hands and feet is being developed. In this work, a numerical simulation of the MSI system is presented. The purpose of the simulation is to determine the optimal design parameters. Inflamed and unaffected human joint models were constructed with a realistic geometry and tissue distributions, based on a MRI scan of a human finger with a spatial resolution of 0.2 mm. The light transport simulation is based on a weighted-photon 3D Monte Carlo method utilizing CUDA GPU acceleration. An uniform illumination of the finger within the 400-1100 nm spectral range was simulated and the photons exiting the joint were recorded using different acceptance angles. From the obtained reflectance and transmittance images the spectral and spatial features most indicative of inflammation were identified. Optimal acceptance angle and spectral bands were determined. This study demonstrates that proper selection of MSI system parameters critically affects ability of a MSI system to discriminate the unaffected and inflamed joints. The presented system design optimization approach could be applied to other pathologies.

  11. Using ground penetrating radar in levee assessment to detect small scale animal burrows

    Science.gov (United States)

    Chlaib, Hussein K.; Mahdi, Hanan; Al-Shukri, Haydar; Su, Mehmet M.; Catakli, Aycan; Abd, Najah

    2014-04-01

    Levees are civil engineering structures built to protect human lives, property, and agricultural lands during flood events. To keep these important structures in a safe condition, continuous monitoring must be performed regularly and thoroughly. Small rodent burrows are one of the major defects within levees; however, their early detection and repair helps in protecting levees during flooding events. A set of laboratory experiments was conducted to analyze the polarity change in GPR signals in the presence of subsurface voids and water-filled cavities. Ground Penetrating Radar (GPR) surveys using multi frequency antennas (400 MHz and 900 MHz) were conducted along an 875 meter section of the Lollie Levee near Conway, Arkansas, USA, to assess the levee's structural integrity. Many subsurface animal burrows, water-filled cavities, clay clasts, and metallic objects were investigated and identified. These anomalies were located at different depths and have different sizes. To ground truth the observations, hand dug trenches were excavated to confirm several anomalies. Results show an excellent match between GPR interpreted anomalies and the observed features. In-situ dielectric constant measurements were used to calculate the feature depths. The results of this research show that the 900 MHz antenna has more advantages over the 400 MHz antenna.

  12. Detecting small attractors of large Boolean networks by function-reduction-based strategy.

    Science.gov (United States)

    Zheng, Qiben; Shen, Liangzhong; Shang, Xuequn; Liu, Wenbin

    2016-04-01

    Boolean networks (BNs) are widely used to model gene regulatory networks and to design therapeutic intervention strategies to affect the long-term behaviour of systems. A central aim of Boolean-network analysis is to find attractors that correspond to various cellular states, such as cell types or the stage of cell differentiation. This problem is NP-hard and various algorithms have been used to tackle it with considerable success. The idea is that a singleton attractor corresponds to n consistent subsequences in the truth table. To find these subsequences, the authors gradually reduce the entire truth table of Boolean functions by extending a partial gene activity profile (GAP). Not only does this process delete inconsistent subsequences in truth tables, it also directly determines values for some nodes not extended, which means it can abandon the partial GAPs that cannot lead to an attractor as early as possible. The results of simulation show that the proposed algorithm can detect small attractors with length p = 4 in BNs of up to 200 nodes with average indegree K = 2.

  13. Quantification, improvement, and harmonization of small lesion detection with state-of-the-art PET

    Energy Technology Data Exchange (ETDEWEB)

    Vos, Charlotte S. van der [Radboud University Medical Centre, Department of Radiology and Nuclear Medicine, Nijmegen (Netherlands); University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Enschede (Netherlands); Koopman, Danielle [University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Enschede (Netherlands); Isala Hospital, Department of Nuclear Medicine, Zwolle (Netherlands); Rijnsdorp, Sjoerd; Arends, Albert J. [Catharina Hospital, Department of Medical Physics, Eindhoven (Netherlands); Boellaard, Ronald [University of Groningen, University Medical Centre Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); VU University Medical Center, Department of Radiology and Nuclear Medicine, Amsterdam (Netherlands); Dalen, Jorn A. van [Isala Hospital, Department of Nuclear Medicine, Zwolle (Netherlands); Isala, Department of Medical Physics, Zwolle (Netherlands); Lubberink, Mark [Uppsala University, Department of Surgical Sciences, Uppsala (Sweden); Uppsala University Hospital, Department of Medical Physics, Uppsala (Sweden); Willemsen, Antoon T.M. [University of Groningen, University Medical Centre Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); Visser, Eric P. [Radboud University Medical Centre, Department of Radiology and Nuclear Medicine, Nijmegen (Netherlands)

    2017-08-15

    In recent years, there have been multiple advances in positron emission tomography/computed tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT scanners introduces new hardware, software, and acquisition methods. This review describes these new developments, which include time-of-flight (TOF), point-spread-function (PSF), maximum-a-posteriori (MAP) based reconstruction, smaller voxels, respiratory gating, metal artefact reduction, and administration of quadratic weight-dependent {sup 18}F-fluorodeoxyglucose (FDG) activity. Also, hardware developments such as continuous bed motion (CBM), (digital) solid-state photodetectors and combined PET and magnetic resonance (MR) systems are explained. These novel techniques have a significant impact on cancer imaging, as they result in better image quality, improved small lesion detectability, and more accurate quantification of radiopharmaceutical uptake. This influences cancer diagnosis and staging, as well as therapy response monitoring and radiotherapy planning. Finally, the possible impact of these developments on the European Association of Nuclear Medicine (EANM) guidelines and EANM Research Ltd. (EARL) accreditation for FDG-PET/CT tumor imaging is discussed. (orig.)

  14. Quantification, improvement, and harmonization of small lesion detection with state-of-the-art PET

    International Nuclear Information System (INIS)

    Vos, Charlotte S. van der; Koopman, Danielle; Rijnsdorp, Sjoerd; Arends, Albert J.; Boellaard, Ronald; Dalen, Jorn A. van; Lubberink, Mark; Willemsen, Antoon T.M.; Visser, Eric P.

    2017-01-01

    In recent years, there have been multiple advances in positron emission tomography/computed tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT scanners introduces new hardware, software, and acquisition methods. This review describes these new developments, which include time-of-flight (TOF), point-spread-function (PSF), maximum-a-posteriori (MAP) based reconstruction, smaller voxels, respiratory gating, metal artefact reduction, and administration of quadratic weight-dependent 18 F-fluorodeoxyglucose (FDG) activity. Also, hardware developments such as continuous bed motion (CBM), (digital) solid-state photodetectors and combined PET and magnetic resonance (MR) systems are explained. These novel techniques have a significant impact on cancer imaging, as they result in better image quality, improved small lesion detectability, and more accurate quantification of radiopharmaceutical uptake. This influences cancer diagnosis and staging, as well as therapy response monitoring and radiotherapy planning. Finally, the possible impact of these developments on the European Association of Nuclear Medicine (EANM) guidelines and EANM Research Ltd. (EARL) accreditation for FDG-PET/CT tumor imaging is discussed. (orig.)

  15. Small leak detection by measuring surface oscillation during sodium-water reaction in steam generator

    International Nuclear Information System (INIS)

    Nei, Hiromichi; Hori, Masao

    1977-01-01

    Small leak sodium-water reaction tests were conducted to develop various kinds of leak detectors for the sodium-heated steam generator in FBR. The super-heated steam was injected into sodium in a reaction vessel having a sodium free surface, simulating the steam generator. The level gauge in the reaction vessel generated the most reliable signal among detectors, as long as the leak rates were relatively high. The level gauge signal was estimated to be the sodium surface oscillation caused by hydrogen bubbles produced in sodium-water reaction. Experimental correlation was derived, predicting the amplitude as a function of leak rate, hydrogen dissolution ratio, bubble rise velocity and other parameters concerned, assuming that the surface oscillation is in proportion to the gas hold-up. The noise amplitude under normal operation without water leak was increased with sodium flow rate and found to be well correlated with Froud number. These two correlations predict that a water leak in a ''MONJU'' class (300 MWe) steam generator could possibly be detected by level gauges at a leak rate above 2 g/sec. (auth.)

  16. Ultrasonic Detection of Small Crack in Studs[Bolts] by Time Difference of Thread Signals(TDTS)

    International Nuclear Information System (INIS)

    Suh, D. M.; Park, D. Y.; Kim, C. K.

    1990-01-01

    It is difficult to detect such flaws as stress - corrosion cracking or corrosion wastage(loss of bolt diameter) in the threads. In many cases the critical size of a flaw is very small(1-2 mm order). This paper describes how it is possible to discriminate small flaw indications in threads using the time difference or thread signals(TDTS) by a signal-conditioning technique

  17. Classification of Intact Stability Standards for Dynamically Supported Craft.

    Science.gov (United States)

    1979-10-01

    introduced (by the U.S. Navy) in the late 1950’s. Both military and commercial applications of this type have since proved very successful . From the... successful and safe planing craft have been built for military, commercial and private use. The stability of planing craft, however, is an extremely...forlces. Broaching- [ n I, 111, I ikeA LL) tOCCUr in suvvre following seas, when the Cr aft runs do L tht ! act of ort wav docd slope- ts bovw Ma’ thes

  18. Formation control of surface marine craft using Lagrange multipliers

    DEFF Research Database (Denmark)

    Ihle, Ivar-Andre F.; Jouffroy, Jerome; Fossen, Thor I.

    We propose a method for constructing control laws for formation control of marine craft using classical tools from analytical mechanics. The control law is based on applying inter-vessel constraint functions which again impose forces on the individual vessels that maintain the given constraints...... on the total system. In this way, a formation can be assembled and stay together when exposed to external forces. A brief comparison with other control designs for a group of marine craft is done. Further, control laws for formation assembling (with dynamic positioning), and formation keeping during...

  19. Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa.

    Science.gov (United States)

    Cronjé, Nadine; Schwartz, Ilan S; Retief, Liezl; Bastos, Armanda D S; Matthee, Sonja; Preiser, Wolfgang; Bennett, Nigel C; Maphanga, Tsidiso; Govender, Nelesh P; Colebunders, Robert; Kenyon, Chris

    2018-06-01

    The ecological niche of Emergomyces africanus (formerly Emmonsia species), a dimorphic fungus that causes an AIDS-related mycosis in South Africa, is unknown. We hypothesized that natural infection with E. africanus occurs in wild small mammals. Using molecular detection with primers specific for E. africanus, we examined 1402 DNA samples from 26 species of mole-rats, rodents, and insectivores trapped in South Africa that included 1324 lung, 37 kidney, and 41 liver specimens. DNA of E. africanus was not detected in any animals. We conclude that natural infection of wild small mammals in South Africa with E. africanus has not been proven.

  20. Transformational leadership, adaptability, and job crafting : the moderating role of organizational identification.

    NARCIS (Netherlands)

    Wang, H.; Demerouti, E.; Le Blanc, P.M.

    In this study, we aim to explore the link between transformational leadership and job crafting. We predict that transformational leadership will stimulate employee job crafting (seeking resources, seeking challenges, and reducing demands) by increasing their adaptability; but that transformational

  1. Marian Roberts, Developing the Craft of Mediation: Reflections on Theory and Practice

    Directory of Open Access Journals (Sweden)

    Ghislaine M. Lanteigne

    2008-10-01

    Full Text Available In Developing the Craft of Mediation, Marian Roberts proposes that mediation is akin to a craft with its focus on learning from experience and from others working in the field to develop and master knowledge and skills.

  2. A computer-aided detection (CAD) system with a 3D algorithm for small acute intracranial hemorrhage

    Science.gov (United States)

    Wang, Ximing; Fernandez, James; Deshpande, Ruchi; Lee, Joon K.; Chan, Tao; Liu, Brent

    2012-02-01

    Acute Intracranial hemorrhage (AIH) requires urgent diagnosis in the emergency setting to mitigate eventual sequelae. However, experienced radiologists may not always be available to make a timely diagnosis. This is especially true for small AIH, defined as lesion smaller than 10 mm in size. A computer-aided detection (CAD) system for the detection of small AIH would facilitate timely diagnosis. A previously developed 2D algorithm shows high false positive rates in the evaluation based on LAC/USC cases, due to the limitation of setting up correct coordinate system for the knowledge-based classification system. To achieve a higher sensitivity and specificity, a new 3D algorithm is developed. The algorithm utilizes a top-hat transformation and dynamic threshold map to detect small AIH lesions. Several key structures of brain are detected and are used to set up a 3D anatomical coordinate system. A rule-based classification of the lesion detected is applied based on the anatomical coordinate system. For convenient evaluation in clinical environment, the CAD module is integrated with a stand-alone system. The CAD is evaluated by small AIH cases and matched normal collected in LAC/USC. The result of 3D CAD and the previous 2D CAD has been compared.

  3. Bringing Strategic Clarity to Your Grantmaking: Crafting and Using a Theory of Change. GFE Annual Conference (10th, San Francisco, California, November 6-8, 2006)

    Science.gov (United States)

    Grantmakers for Education, 2006

    2006-01-01

    To provide an even more intensive learning experience at Grantmakers for Education's 2006 conference, the program featured a conference "study group." This special small-group program track focused on foundation strategy and the value of a well-crafted theory of change for increasing strategic clarity and impact. This report is intended to make…

  4. Job crafting, work engagement, and psychological distress among Japanese employees: a cross-sectional study

    OpenAIRE

    Sakuraya, Asuka; Shimazu, Akihito; Eguchi, Hisashi; Kamiyama, Kimika; Hara, Yujiro; Namba, Katsuyuki; Kawakami, Norito

    2017-01-01

    Background Job crafting, an employee-initiated job design/redesign, has become important for employees? well-being. However, most studies on the relationship between job crafting and employees? well-being have been conducted in western countries; thus, it is unclear whether job crafting can be effectively applied to Asian cultures, such as Japan, which emphasizes group harmony. The aim of this study was to examine the cross-sectional associations of self-reported job crafting with work engage...

  5. Malleable Thought: The Role of Craft Thinking in Practice-Led Graphic Design

    Science.gov (United States)

    Ings, Welby

    2015-01-01

    This article considers the potential of craft processes as creative engagements in graphic design research. It initially discusses the uneasy history of craft within the discipline, then draws upon case studies undertaken by three established designers who, in their postgraduate theses, engaged with craft as a process of thinking. In doing so, the…

  6. 46 CFR 199.220 - Survival craft and rescue boat embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft and rescue boat embarkation arrangements... APPLIANCES AND ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.220 Survival craft and rescue boat embarkation arrangements. (a) Survival craft...

  7. 46 CFR 199.175 - Survival craft and rescue boat equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft and rescue boat equipment. 199.175....175 Survival craft and rescue boat equipment. (a) All lifeboat and rescue boat equipment— (1) Must be... craft or rescue boat; or (iii) Overload the launching appliance. (b) Each lifeboat, rigid liferaft, and...

  8. 47 CFR 80.271 - Technical requirements for portable survival craft radiotelephone transceivers.

    Science.gov (United States)

    2010-10-01

    ... craft radiotelephone transceivers. 80.271 Section 80.271 Telecommunication FEDERAL COMMUNICATIONS... Authorization for Compulsory Ships § 80.271 Technical requirements for portable survival craft radiotelephone transceivers. (a) Portable survival craft radiotelephone transceivers must comply with the following: (1) The...

  9. 46 CFR 199.110 - Survival craft muster and embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 199... § 199.110 Survival craft muster and embarkation arrangements. (a) Each muster station must have... emergency source of electrical power. (e) Each davit-launched and free-fall survival craft muster station...

  10. 33 CFR 149.313 - How must survival craft be arranged?

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false How must survival craft be... Equipment Manned Deepwater Port Requirements § 149.313 How must survival craft be arranged? The operator must arrange survival craft so that they meet the requirements of 46 CFR 108.525 (a) and § 108.530 and...

  11. 46 CFR 108.550 - Survival craft launching and recovery arrangements: General.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements...-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.550 Survival craft.... (c) Each survival craft must be arranged to clear each leg, column, footing, brace, mat, and each...

  12. 46 CFR 180.206 - Survival craft-vessels operating on Great Lakes routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on Great Lakes routes... Craft § 180.206 Survival craft—vessels operating on Great Lakes routes. (a) Except as allowed by... with the survival craft required by § 180.205 (a) through (e), as appropriate. (b) Each vessel...

  13. 46 CFR 199.150 - Survival craft launching and recovery arrangements; general.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements... Vessels § 199.150 Survival craft launching and recovery arrangements; general. (a)(1) Each launching...) Unless expressly provided otherwise in this part, each survival craft must be provided with a launching...

  14. 26 CFR 1.861-16 - Income from certain craft first leased after December 28, 1980.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Income from certain craft first leased after... the United States § 1.861-16 Income from certain craft first leased after December 28, 1980. (a) General rule. If a taxpayer— (1) Owns a qualified craft (as defined in paragraph (b) of this section). (2...

  15. 76 FR 38153 - California State Nonroad Engine Pollution Control Standards; Commercial Harbor Craft Regulations...

    Science.gov (United States)

    2011-06-29

    ... Standards; Commercial Harbor Craft Regulations; Opportunity for Public Hearing and Comment AGENCY... engines on commercial harbor craft. CARB has requested that EPA issue a new authorization under [email protected] . SUPPLEMENTARY INFORMATION: I. California's Commercial Harbor Craft Regulations In a...

  16. 46 CFR 133.110 - Survival craft muster and embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 133... VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.110 Survival craft muster and embarkation... lighting supplied from the emergency source of electrical power. (e) Each davit-launched survival craft...

  17. 46 CFR 109.323 - Manning of survival craft and supervision.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Manning of survival craft and supervision. 109.323... DRILLING UNITS OPERATIONS Operation and Stowage of Safety Equipment § 109.323 Manning of survival craft and supervision. (a) There must be a sufficient number of trained persons on board the survival craft for...

  18. 46 CFR 180.205 - Survival craft-vessels operating on limited coastwise routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on limited coastwise... Craft § 180.205 Survival craft—vessels operating on limited coastwise routes. (a) Except as allowed by... survival craft required by § 180.204(d). (e) Each vessel certificated to operate on a limited coastwise...

  19. 33 CFR 149.305 - What are the survival craft requirements for temporary personnel?

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What are the survival craft... EQUIPMENT Lifesaving Equipment Manned Deepwater Port Requirements § 149.305 What are the survival craft... complement exceeds the capacity of the survival craft required under § 149.304 of this subpart, the port must...

  20. 46 CFR 199.100 - Manning of survival craft and supervision.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Manning of survival craft and supervision. 199.100....100 Manning of survival craft and supervision. (a) There must be a sufficient number of trained... craft and launching arrangements required for abandonment by the total number of persons on board. (c...

  1. 46 CFR 199.245 - Survival craft embarkation and launching arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation and launching arrangements... Passenger Vessels § 199.245 Survival craft embarkation and launching arrangements. (a) Each davit-launched liferaft must be arranged to be rapidly boarded by its full complement of persons. (b) All survival craft...

  2. 46 CFR 199.280 - Survival craft embarkation and launching arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation and launching arrangements... Cargo Vessels § 199.280 Survival craft embarkation and launching arrangements. (a) Each lifeboat must be.... (d) All survival craft required for abandonment by the total number of persons on board must be...

  3. 46 CFR 133.150 - Survival craft launching and recovery arrangements: General.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements...) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.150 Survival craft launching and recovery arrangements: General. (a) All survival craft required for abandonment by the total number of...

  4. 46 CFR 180.207 - Survival craft-vessels operating on lakes, bays, and sounds routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on lakes, bays, and... Survival Craft § 180.207 Survival craft—vessels operating on lakes, bays, and sounds routes. (a) Except as... warm water is not required to carry survival craft. (d) A vessel certificated to operate on lakes, bays...

  5. 46 CFR 117.202 - Survival craft-vessels operating on oceans routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-vessels operating on oceans routes. 117... LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 117.202 Survival craft—vessels... number of overnight persons allowed, the survival craft requirements contained in paragraph (e) of this...

  6. 46 CFR 117.208 - Survival craft-vessels operating on rivers routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-vessels operating on rivers routes. 117... LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 117.208 Survival craft—vessels... vessel certificated to operate on a rivers route in warm water is not required to carry survival craft...

  7. Valuing Craftsmanship: In particular the crafting of Chinese porcelain and Dutch Delft Blue

    NARCIS (Netherlands)

    L. Jiang (Lili)

    2018-01-01

    markdownabstract“How important are crafts for a society?” When a conventional economist gets the question, the answer is most likely about the prices of craft products, the income of craftspeople, and the contribution that the crafts sector makes to GDP. This thesis gives another answer. Applying

  8. Application of photostable quantum dots for indirect immunofluorescent detection of specific bacterial serotypes on small marine animals

    International Nuclear Information System (INIS)

    Decho, Alan W; Beckman, Erin M; Chandler, G Thomas; Kawaguchi, Tomohiro

    2008-01-01

    An indirect immunofluorescence approach was developed using semiconductor quantum dot nanocrystals to label and detect a specific bacterial serotype of the bacterial human pathogen Vibrio parahaemolyticus, attached to small marine animals (i.e. benthic harpacticoid copepods), which are suspected pathogen carriers. This photostable labeling method using nanotechnology will potentially allow specific serotypes of other bacterial pathogens to be detected with high sensitivity in a range of systems, and can be easily applied for sensitive detection to other Vibrio species such as Vibrio cholerae

  9. Fully automated microchip system for the detection of quantal exocytosis from single and small ensembles of cells

    DEFF Research Database (Denmark)

    Spégel, Christer; Heiskanen, Arto; Pedersen, Simon

    2008-01-01

    A lab-on-a-chip device that enables positioning of single or small ensembles of cells on an aperture in close proximity to a mercaptopropionic acid (MPA) modified sensing electrode has been developed and characterized. The microchip was used for the detection of Ca2+-dependent quantal catecholamine...

  10. D Digital Simulation of Minnan Temple Architecture CAISSON'S Craft Techniques

    Science.gov (United States)

    Lin, Y. C.; Wu, T. C.; Hsu, M. F.

    2013-07-01

    Caisson is one of the important representations of the Minnan (southern Fujian) temple architecture craft techniques and decorative aesthetics. The special component design and group building method present the architectural thinking and personal characteristics of great carpenters of Minnan temple architecture. In late Qing Dynasty, the appearance and style of caissons of famous temples in Taiwan apparently presented the building techniques of the great carpenters. However, as the years went by, the caisson design and craft techniques were not fully inherited, which has been a great loss of cultural assets. Accordingly, with the caisson of Fulong temple, a work by the well-known great carpenter in Tainan as an example, this study obtained the thinking principles of the original design and the design method at initial period of construction through interview records and the step of redrawing the "Tng-Ko" (traditional design, stakeout and construction tool). We obtained the 3D point cloud model of the caisson of Fulong temple using 3D laser scanning technology, and established the 3D digital model of each component of the caisson. Based on the caisson component procedure obtained from interview records, this study conducted the digital simulation of the caisson component to completely recode and present the caisson design, construction and completion procedure. This model of preserving the craft techniques for Minnan temple caisson by using digital technology makes specific contribution to the heritage of the craft techniques while providing an important reference for the digital preservation of human cultural assets.

  11. Productive and counterproductive job crafting: A daily diary study.

    Science.gov (United States)

    Demerouti, Evangelia; Bakker, Arnold B; Halbesleben, Jonathon R B

    2015-10-01

    The present study aims to uncover the way daily job crafting influences daily job performance (i.e., task performance, altruism, and counterproductive work behavior). Job crafting was conceptualized as "seeking resources," "seeking challenges," and "reducing demands" and viewed as strategies individuals use to optimize their job characteristics. We hypothesized that daily job crafting relates to daily job demands and resources (work pressure and autonomy), which consequently relate to daily work engagement and exhaustion and ultimately to job performance. A sample of 95 employees filled in a quantitative diary for 5 consecutive working days (n occasions = 475). We predicted and found that daily seeking resources was positively associated with daily task performance because daily autonomy and work engagement increased. In contrast, daily reducing demands was detrimental for daily task performance and altruism, because employees lower their daily workload and consequently their engagement and exhaustion, respectively. Only daily seeking challenges was positively (rather than negatively) associated with daily counterproductive behavior. We conclude that employee job crafting can have both beneficial and detrimental effects on job performance. (c) 2015 APA, all rights reserved).

  12. Ghanaian Craft Exporters in the Global Market: Binding and Missing ...

    African Journals Online (AJOL)

    Agribotix GCS 068

    The paper explored the benefits that accrue to Ghanaian craft exporters from subcontracting ties .... viewed as important channels for providing effective and cheaper bases for economic development ... member negatively affect the reputation and cohesion of the group and therefore ...... Unpublished PhD Thesis, University.

  13. Effectiveness of a Volunteer-Led Crafts Group Intervention amongst ...

    African Journals Online (AJOL)

    The purpose of this study was to determine the effectiveness of a volunteer led crafts group intervention (VLCG) as an adjunct to antidepressant medication on mild to moderately depressed women. A quasi-experimental, non-equivalent, control group study was conducted in an urban, psychiatric clinic. Depression was ...

  14. Artisans, Architects, and Apprentices: Valuing the Craft of Teacher Education

    Science.gov (United States)

    Boyd Potter, Rachel

    2016-01-01

    In this article, Boyd Potter describes teacher education faculty as both artisans and architects. As artisans, it is not only their products that enrich us; it is the art of the craft itself that shapes their work. An artisan is valued for the creative endeavor, and not solely the masterpiece. Preparing a quality teacher is not easy work, while…

  15. Bottom Raking Damage to High-Speed Craft

    DEFF Research Database (Denmark)

    Simonsen, Bo Cerup

    1998-01-01

    This paper presents a comparative study of the raking damage to high speed craft (HSC) and conventional ships. The analysis is based on a detailed theoretical model for the raking resistance of an assembled ship bottom structure and on the idea that the impact conditions for various ship types have...

  16. Classroom Teachers' Craft Knowledge of Their Inclusive Practice

    Science.gov (United States)

    Black-Hawkins, Kristine; Florian, Lani

    2012-01-01

    Whilst recent decades have seen significant progress in research on inclusive education, many teachers still feel that the research literature does not fully address their professional concerns about how to enact a policy of inclusion in their classrooms. To help to bridge this gap, we drew on the concept of craft knowledge to undertake a detailed…

  17. Arts, Crafts and Indigenous Industries in Nigeria | Yakubu | Journal ...

    African Journals Online (AJOL)

    The paper is illustrative of the cultural wealth of Nigeria in terms of arts and crafts. It provides a descriptive picture of the various characteristics of the genres in the past and present and in traditional as well as modern Nigerian communities. It functions within religious, intellectual, and socio-economic contexts. Hence ...

  18. Ghanaian Craft Exporters in the Global Market: Binding and Missing ...

    African Journals Online (AJOL)

    The strong positions of buyers and export agents in the craft value chain enable them to apply sanctions to extract compliance from the exporters whereas the weak position of the export vendors implies the lack of sanctioning authority over the rogue artisan subcontractors. The government's promotion programmes could ...

  19. Transferring PSM craft skills in a 2 hour session

    NARCIS (Netherlands)

    Zijderveld, E.J.A. van; Morill, N.; Shaw, D.; Belton, V.; Harvey, P.; Rouwette, E.

    2007-01-01

    Many of those involved in the Problem Structuring Methods (PSM) community have commented on the struggle that novices face in building the craft skills associated with conducting a PSM intervention. As part of this year's Operational Research Society Conference, we have three 2-hour practical

  20. Beyond Talent: John Irving and the Passionate Craft of Creativity.

    Science.gov (United States)

    Amabile, Teresa M.

    2001-01-01

    Uses the thoughts and work of novelist John Irving to illustrate the prominence of non-talent components in the componential model of creativity, explaining that raw talent, clever imagination, and a creative personality are insufficient to ensure creative success and that hard work and love of a craft (intrinsic motivation) are at least as…

  1. Reading the Writer's Craft: The Hemingway Short Stories

    Science.gov (United States)

    Garrigues, Lisa

    2004-01-01

    The high school students who spent five weeks studying the style and craft of Ernest Hemingway experienced the power and plus points of apprenticeships. Several assignments that helped the high school juniors to analyze Hemingway's work on short stories and learn from this master craftsman are presented.

  2. Robust formation control of marine surface craft using Lagrange multipliers

    DEFF Research Database (Denmark)

    Ihle, Ivar-Andre F.; Jouffroy, Jerome; Fossen, Thor I.

    2006-01-01

    This paper presents a formation modelling scheme based on a set of inter-body constraint functions and Lagrangian multipliers. Formation control for a °eet of marine craft is achieved by stabilizing the auxiliary constraints such that the desired formation con¯guration appears. In the proposed fr...

  3. The Validity of the School Assessment in the Craft Subject

    Directory of Open Access Journals (Sweden)

    Antti Hilmola

    2016-06-01

    Full Text Available In this research project, the validity of the school assessment is examined in the craft subject in Finland’s basic education. The criteria for the school assessment are based on the Finnish Na-tional Core Curriculum (FNCC in which the idea of the Entire Craft (EC is highlighted. How-ever, the discussion as to whether or not the school practice is based on the idea of EC, or whether the teachers are still focused on the technical details of products in reflecting on the pupils’ tool-handling skills, is still an ongoing debate. Learner-centred learning is implicated in EC since the pupils are expected to set goals for the implementation of their own ideating, plan-ning and constructing. And, finally, in such a process, the self-reflection of the implemented out-comes against the goals will take place.  Altogether 73 craft teachers from 59 upper level schools participated in this research project. The pupils’ (N = 982 success was assessed during an EC period using the indicator validated by the previous nation-wide evaluation by the Finn-ish National Board of Education (FNBE. Since the valid school assessment was expected to reflect the success in the Entire Craft Assessment Period (ECAP, the outcomes were assessed against the criteria of the FNCC and compared to the pupils’ school scores. The data was ana-lysed using the Linear Regression Analysis (Enter Method. The central observation was that the pupils’ success in the criteria of the EC do not reflect the 7th grade school scores, in all re-spects. Moreover, the pupils’ success does not reflect the 6th grade school scores. The instruc-tions and supplementary education of the FNCC criteria are needed for craft teachers, especial-ly for class teachers at the lower level. In Finland, also the craft subject is taught by the class teachers at the lower level while, at the upper level, the subject teachers take their place. Ac-cording to the new FNCC, the number of class lessons will be

  4. Job crafting in schools for special education: A qualitative analysis [Job crafting in het speciaal onderwijs: Een kwalitatieve analyse

    NARCIS (Netherlands)

    Wingerden, J. van; Derks, D.; Bakker, A.B.; Dorenbosch, L.

    2013-01-01

    In this article we discuss the design and qualitative (process) evaluation of a job crafting intervention among employees at three Dutch schools for special education. In a period of 1.5 months, fifty employees participated in a group-based training intervention that addressed individual's job

  5. High sensitivity of quick view capsule endoscopy for detection of small bowel Crohn's disease

    DEFF Research Database (Denmark)

    Halling, Morten Lee; Nathan, Torben; Kjeldsen, Jens

    2014-01-01

    Capsule endoscopy (CE) has a high sensitivity for diagnosing small bowel Crohn's disease, but video analysis is time consuming. The quick view (qv) function is an effective tool to reduce time consumption. The aim of this study was to determine the rate of missed small bowel ulcerations with qv-C...

  6. Recursive estimation techniques for detection of small objects in infrared image data

    Science.gov (United States)

    Zeidler, J. R.; Soni, T.; Ku, W. H.

    1992-04-01

    This paper describes a recursive detection scheme for point targets in infrared (IR) images. Estimation of the background noise is done using a weighted autocorrelation matrix update method and the detection statistic is calculated using a recursive technique. A weighting factor allows the algorithm to have finite memory and deal with nonstationary noise characteristics. The detection statistic is created by using a matched filter for colored noise, using the estimated noise autocorrelation matrix. The relationship between the weighting factor, the nonstationarity of the noise and the probability of detection is described. Some results on one- and two-dimensional infrared images are presented.

  7. Real-Time Fabric Defect Detection Using Accelerated Small-Scale Over-Completed Dictionary of Sparse Coding

    Directory of Open Access Journals (Sweden)

    Tianpeng Feng

    2016-01-01

    Full Text Available An auto fabric defect detection system via computer vision is used to replace manual inspection. In this paper, we propose a hardware accelerated algorithm based on a small-scale over-completed dictionary (SSOCD via sparse coding (SC method, which is realized on a parallel hardware platform (TMS320C6678. In order to reduce computation, the image patches projections in the training SSOCD are taken as features and the proposed features are more robust, and exhibit obvious advantages in detection results and computational cost. Furthermore, we introduce detection ratio and false ratio in order to measure the performance and reliability of the hardware accelerated algorithm. The experiments show that the proposed algorithm can run with high parallel efficiency and that the detection speed meets the real-time requirements of industrial inspection.

  8. Methodological considerations for detection of terrestrial small-body salamander eDNA and implications for biodiversity conservation

    Science.gov (United States)

    Walker, Donald M.; Leys, Jacob E.; Dunham, Kelly E.; Oliver, Joshua C.; Schiller, Emily E.; Stephenson, Kelsey S.; Kimrey, John T.; Wooten, Jessica; Rogers, Mark W.

    2017-01-01

    Environmental DNA (eDNA) can be used as an assessment tool to detect populations of threatened species and provide fine-scale data required to make management decisions. The objectives of this project were to use quantitative PCR (qPCR) to: (i) detect spiked salamander DNA in soil, (ii) quantify eDNA degradation over time, (iii) determine detectability of salamander eDNA in a terrestrial environment using soil, faeces, and skin swabs, (iv) detect salamander eDNA in a mesocosm experiment. Salamander eDNA was positively detected in 100% of skin swabs and 66% of faecal samples and concentrations did not differ between the two sources. However, eDNA was not detected in soil samples collected from directly underneath wild-caught living salamanders. Salamander genomic DNA (gDNA) was detected in all qPCR reactions when spiked into soil at 10.0, 5.0, and 1.0 ng/g soil and spike concentration had a significant effect on detected concentrations. Only 33% of samples showed recoverable eDNA when spiked with 0.25 ng/g soil, which was the low end of eDNA detection. To determine the rate of eDNA degradation, gDNA (1 ng/g soil) was spiked into soil and quantified over seven days. Salamander eDNA concentrations decreased across days, but eDNA was still amplifiable at day 7. Salamander eDNA was detected in two of 182 mesocosm soil samples over 12 weeks (n = 52 control samples; n = 65 presence samples; n = 65 eviction samples). The discrepancy in detection success between experiments indicates the potential challenges for this method to be used as a monitoring technique for small-bodied wild terrestrial salamander populations.

  9. Real Time Corner Detection for Miniaturized Electro-Optical Sensors Onboard Small Unmanned Aerial Systems

    Directory of Open Access Journals (Sweden)

    Antonio Moccia

    2012-01-01

    Full Text Available This paper describes the target detection algorithm for the image processor of a vision-based system that is installed onboard an unmanned helicopter. It has been developed in the framework of a project of the French national aerospace research center Office National d’Etudes et de Recherches Aérospatiales (ONERA which aims at developing an air-to-ground target tracking mission in an unknown urban environment. In particular, the image processor must detect targets and estimate ground motion in proximity of the detected target position. Concerning the target detection function, the analysis has dealt with realizing a corner detection algorithm and selecting the best choices in terms of edge detection methods, filtering size and type and the more suitable criterion of detection of the points of interest in order to obtain a very fast algorithm which fulfills the computation load requirements. The compared criteria are the Harris-Stephen and the Shi-Tomasi, ones, which are the most widely used in literature among those based on intensity. Experimental results which illustrate the performance of the developed algorithm and demonstrate that the detection time is fully compliant with the requirements of the real-time system are discussed.

  10. Investigation on location-dependent detectability of a small mass for digital breast tomosynthesis evaluation

    Science.gov (United States)

    Lee, Changwoo; Baek, Jongduk; Park, Subok

    2016-03-01

    Digital breast tomosynthesis (DBT) is an emerging imaging modality for improved breast cancer detection and diagnosis [1-5]. Numerous efforts have been made to find quantitative metrics associated with mammographic image quality assessment, such as the exponent β of anatomical noise power spectrum, glandularity, contrast noise ratio, etc. [6-8]. In addition, with the use of Fourier-domain detectability for a task-based assessment of DBT, a stationarity assumption on reconstructed image statistics was often made [9-11], resulting in the use of multiple regions-of-interest (ROIs) from different locations in order to increase sample size. While all these metrics provide some information on mammographic image characteristics and signal detection, the relationship between these metrics and detectability in DBT evaluation has not been fully understood. In this work, we investigated spatial-domain detectability trends and levels as a function of the number of slices Ns at three different ROI locations on the same image slice, where background statistics differ in terms of the aforementioned metrics. Detectabilities for the three ROI locations were calculated using multi-slice channelized Hotelling observers with 2D/3D Laguerre-Gauss channels. Our simulation results show that detectability levels and trends as a function of Ns vary across these three ROI locations. They also show that the exponent β, mean glandularity, and mean attenuation coefficient vary across the three ROI locations but they do not necessarily predict the ranking of detectability levels and trends across these ROI locations.

  11. The Occurrence of Beer Spoilage Lactic Acid Bacteria in Craft Beer Production.

    Science.gov (United States)

    Garofalo, Cristiana; Osimani, Andrea; Milanović, Vesna; Taccari, Manuela; Aquilanti, Lucia; Clementi, Francesca

    2015-12-01

    Beer is one of the world's most ancient and widely consumed fermented alcoholic beverages produced with water, malted cereal grains (generally barley and wheat), hops, and yeast. Beer is considered an unfavorable substrate of growth for many microorganisms, however, there are a limited number of bacteria and yeasts, which are capable of growth and may spoil beer especially if it is not pasteurized or sterile-filtered as craft beer. The aim of this research study was to track beer spoilage lactic acid bacteria (LAB) inside a brewery and during the craft beer production process. To that end, indoor air and work surface samples, collected in the brewery under study, together with commercial active dry yeasts, exhausted yeasts, yeast pellet (obtained after mature beer centrifugation), and spoiled beers were analyzed through culture-dependent methods and PCR-DGGE in order to identify the contaminant LAB species and the source of contamination. Lactobacillus brevis was detected in a spoiled beer and in a commercial active dry yeast. Other LAB species and bacteria ascribed to Staphylococcus sp., Enterobaceriaceae, and Acetobacter sp. were found in the brewery. In conclusion, the PCR-DGGE technique coupled with the culture-dependent method was found to be a useful tool for identifying the beer spoilage bacteria and the source of contamination. The analyses carried out on raw materials, by-products, final products, and the brewery were useful for implementing a sanitization plan to be adopted in the production plant. © 2015 Institute of Food Technologists®

  12. O activismo estético feminista de Nikki Craft Nikki Craft's aesthetic feminist activism

    Directory of Open Access Journals (Sweden)

    Rui Pedro Fonseca

    2010-12-01

    Full Text Available Uma das condições para que na sociedade sejam alicerçados valores de género misóginos consiste na existência de uma estrutura de produção cultural heterossexual compulsiva, dominante e universalista que estabeleça princípios de representação dos sexos claramente diferenciados, que tendam a favorecer mais o homem em detrimento da mulher. Partimos de um princípio de que a produção da cultura origina processos de reprodução, o que significa, em termos práticos, que a representação de signos, códigos, valores e comportamentos associados aos sexos é potencialmente materializada nas sociedades, por homens e por mulheres. Essa tem sido uma batalha levada a cabo por muitas mulheres a partir da segunda vaga do movimento feminista, nomeadamente pela ala mais radical, que tem procurado reivindicar novos paradigmas no que diz respeito às convenções culturais de género. O que propomos neste estudo é analisar algumas das campanhas levadas a cabo por Nikki Craft, uma feminista radical norte-americana que viria a organizar e/ou a protagonizar nos anos 1970 e 1980 vários protestos em espaços públicos de algumas cidades dos Estados Unidos. Neste estudo procuramos clarificar as motivações e as estratégias levadas a cabo por essa feminista, cujos activismos incidiram contra algumas das estruturas culturais (campo da arte, instituições da beleza e indústria pornográfica legitimadoras de representações desencadeadoras de prejuízos para a mulherOne of the conditions for misogynic genders to be settled in society consists on the existence of a compulsive dominant and universal heterosexual cultural production, which establishes clearly differentiated representation principles of both sexes. These representation principles tend to favour more the man, disregarding the woman. We consider that culture production gives origin to reproduction processes, which means that, in practical terms, the representation of signs, codes, values

  13. FDG small animal PET permits early detection of malignant cells in a xenograft murine model

    International Nuclear Information System (INIS)

    Nanni, Cristina; Spinelli, Antonello; Trespidi, Silvia; Ambrosini, Valentina; Castellucci, Paolo; Farsad, Mohsen; Franchi, Roberto; Fanti, Stefano; Leo, Korinne di; Tonelli, Roberto; Pession, Andrea; Pettinato, Cinzia; Rubello, Domenico

    2007-01-01

    The administration of new anticancer drugs in animal models is the first step from in vitro to in vivo pre-clinical protocols. At this stage it is crucial to ensure that cells are in the logarithmic phase of growth and to avoid vascular impairment, which can cause inhomogeneous distribution of the drug within the tumour and thus lead to bias in the final analysis of efficacy. In subcutaneous xenograft murine models, positivity for cancer is visually recognisable 2-3 weeks after inoculation, when a certain amount of necrosis is usually already present. The aim of this study was to evaluate the accuracy of FDG small animal PET for the early detection of malignant masses in a xenograft murine model of human rhabdomyosarcoma. A second goal was to analyse the metabolic behaviour of this xenograft tumour over time. We studied 23 nude mice, in which 7 x 10 6 rhabdomyosarcoma cells (RH-30 cell line) were injected in the dorsal subcutaneous tissues. Each animal underwent four FDG PET scans (GE, eXplore Vista DR) under gas anaesthesia. The animals were studied 2, 5, 14 and 20 days after inoculation. We administered 20 MBq of FDG via the tail vein. Uptake time was 60 min, and acquisition time, 20 min. Images were reconstructed with OSEM 2D iterative reconstruction and the target to background ratio (TBR) was calculated for each tumour. Normal subcutaneous tissue had a TBR of 0.3. Necrosis was diagnosed when one or more cold areas were present within the mass. All the animals were sacrificed and histology was available to verify PET results. PET results were concordant with the findings of necropsy and histology in all cases. The incidence of the tumour was 69.6% (16/23 animals); seven animals did not develop a malignant mass. Ten of the 23 animals had a positive PET scan 2 days after inoculation. Nine of these ten animals developed a tumour; the remaining animal became negative, at the third scan. The positive predictive value of the early PET scan was 90% (9/10 animals

  14. Weak wide-band signal detection method based on small-scale periodic state of Duffing oscillator

    Science.gov (United States)

    Hou, Jian; Yan, Xiao-peng; Li, Ping; Hao, Xin-hong

    2018-03-01

    The conventional Duffing oscillator weak signal detection method, which is based on a strong reference signal, has inherent deficiencies. To address these issues, the characteristics of the Duffing oscillatorʼs phase trajectory in a small-scale periodic state are analyzed by introducing the theory of stopping oscillation system. Based on this approach, a novel Duffing oscillator weak wide-band signal detection method is proposed. In this novel method, the reference signal is discarded, and the to-be-detected signal is directly used as a driving force. By calculating the cosine function of a phase space angle, a single Duffing oscillator can be used for weak wide-band signal detection instead of an array of uncoupled Duffing oscillators. Simulation results indicate that, compared with the conventional Duffing oscillator detection method, this approach performs better in frequency detection intervals, and reduces the signal-to-noise ratio detection threshold, while improving the real-time performance of the system. Project supported by the National Natural Science Foundation of China (Grant No. 61673066).

  15. Small Submersible Robust Microflow Cytometer for Quantitative Detection of Phytoplankton, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Translume will develop an extremely robust, inexpensive micro flow cytometer (mFCM) for quantitative detection of phytoplankton. This device will be designed to be...

  16. Flipping the switch: Tools for detecting small molecule inhibitors of staphylococcal virulence

    Directory of Open Access Journals (Sweden)

    Cassandra L. Quave

    2014-12-01

    Full Text Available Through the expression of the accessory gene regulator (agr quorum sensing cascade, S. aureus is able to produce an extensive array of enzymes, hemolysins and immunomodulators essential to its ability to spread through the host tissues and cause disease. Many have argued for the discovery and development of quorum sensing inhibitors (QSIs to augment existing antibiotics as adjuvant therapies. Here, we discuss the state-of-the-art tools that can be used to conduct screens for the identification of such QSIs. Examples include fluorescent reporters, MS-detection of autoinducing peptide (AIP production, agar plate methods for detection of hemolysins and lipase, HPLC-detection of hemolysins from supernatants, and cell-toxicity assays for detecting damage (or relief thereof against human keratinocyte (HaCat cells. In addition to providing a description of these various approaches, we also discuss their amenability to low-, medium- and high-throughput screening efforts for the identification of novel QSIs.

  17. Leak Detection in Water-Filled Small-Diameter Polyethylene Pipes by Means of Acoustic Emission Measurements

    OpenAIRE

    Alberto Martini; Marco Troncossi; Alessandro Rivola

    2016-01-01

    The implementation of effective strategies to manage leaks represents an essential goal for all utilities involved with drinking water supply in order to reduce water losses affecting urban distribution networks. This study concerns the early detection of leaks occurring in small-diameter customers’ connections to water supply networks. An experimental campaign was carried out in a test bed to investigate the sensitivity of Acoustic Emission (AE) monitoring to water leaks. Damages were artifi...

  18. Evidence of Validity of the Job Crafting Behaviors Scale

    Directory of Open Access Journals (Sweden)

    Renata Silva de Carvalho Chinelato

    2015-12-01

    Full Text Available AbstractJob crafting behavior refers to the changes made by workers in their job context for adjusting their activities to their preferences. We sought to adapt and collect validity evidences of the Job Crafting Behaviors Scale for the Brazilian context, in a sample of 491 workers, with a mean age of 26.7 years. Factor analysis revealed that the final instrument consisted of three dimensions (increasing structural job resources, increasing social job resources, increasing challenging job demands, which showed good internal consistency indexes. These dimensions showed low or moderate correlations with work engagement, positive psychological capital, positive job affect, and in-role performance. The scale showed evidence of validity, the use of which is recommended for future research on the changes that people make in their jobs.

  19. Hypnobirth within the NHS: time to ditch the parent craft?

    Science.gov (United States)

    Gavin-Jones, Teri

    2016-05-01

    Antenatal education within the National Health Service (NHS) is a service in decline within some hospital trusts. Classes on offer are being moved into online formats or discontinued completely. Whilst research into antenatal education remains limited, what is known is that good birth preparation is of value. "Participative preparation for childbirth can enhance women's overall satisfaction with the childbirth experience" (Schrader McMillan et al 2009: 49). There are pockets of excellent antenatal education within the NHS, but no system for regulating the quality and content. Traditional 'parent craft' classes can be oversubscribed, turning what should be a participative group into an audience. Offering good quality antenatal education has the potential to increase normality, improve the birth outcome and the experience of both woman and her birth partner. Is it time to ditch the parent craft and implement dynamic woman-focused education?

  20. Higher-Order Statistics for the Detection of Small Objects in a Noisy Background Application on Sonar Imaging

    Directory of Open Access Journals (Sweden)

    M. Amate

    2007-01-01

    Full Text Available An original algorithm for the detection of small objects in a noisy background is proposed. Its application to underwater objects detection by sonar imaging is addressed. This new method is based on the use of higher-order statistics (HOS that are locally estimated on the images. The proposed algorithm is divided into two steps. In a first step, HOS (skewness and kurtosis are estimated locally using a square sliding computation window. Small deterministic objects have different statistical properties from the background they are thus highlighted. The influence of the signal-to-noise ratio (SNR on the results is studied in the case of Gaussian noise. Mathematical expressions of the estimators and of the expected performances are derived and are experimentally confirmed. In a second step, the results are focused by a matched filter using a theoretical model. This enables the precise localization of the regions of interest. The proposed method generalizes to other statistical distributions and we derive the theoretical expressions of the HOS estimators in the case of a Weibull distribution (both when only noise is present or when a small deterministic object is present within the filtering window. This enables the application of the proposed technique to the processing of synthetic aperture sonar data containing underwater mines whose echoes have to be detected and located. Results on real data sets are presented and quantitatively evaluated using receiver operating characteristic (ROC curves.

  1. Comparative study of diffusion weighted imaging and dynamic contrast enhanced MRI for the detection of small breast cancers

    International Nuclear Information System (INIS)

    Tang Jianhua; Yan Fuhua; Zhou Meiling; Ye Fang; Xu Pengju

    2008-01-01

    Objective: To compare the sensitivity of diffusion weighted imaging (DWI) with dynamic contrast enhanced (DCE) MRI for the detection of small breast cancers and to evaluate the clinical value of DWI. Methods: Forty-eight patients with benign (n=25) and malignant (n=45) small breast lesions (≤2 cm) proved by pathology underwent DWI and DCE MRI. The DCE MRI was performed using FLASH sequence and the time-signal intensity curve was drawn. The DWI was performed using GRAPPA- EPI sequence with different b values (800, 1000 s/mm 2 ) and the ADC values of lesions were measured. The sensitivity and specificity of DWI for the detection of small breast cancers were compared with DCE MRI. Results: Forty of 45 small breast cancers and 19 of 25 small benign breast lesions were correctly diagnosed using DCE MRI. The sensitivity and positive predictive value of TIC were 88.9% (40/45) and 87.0% (40/46). With b values of 800 s/mm 2 and 1000 s/mm 2 , the average ADC values of small breast cancers were (1.153±0.192) x 10 -3 and (1.079±0.186) x 10 -3 mm 2 /s, while those of benign ones were (1.473±0.252) x 10 -3 and (1.419 ± 0.255) x 10 -3 mm 2 /s, respectively. There was no significant difference for the ADC values with different b values in the same group (P>0.05), while there was a significant difference between the malignant and the benign lesions (P 2 . Both the sensitivity and positive predictive value of diagnosis were 86.7% (39/45). The abilities of DWI and DCE MRI for the diagnosis of small breast cancers were the same. The sensitivity (93.3%) and positive predictive value (91.3%) were improved with the combination of DCE MRI and DWI. Conclusion: DWI has a high sensitivity for the detection of small breast cancers, the ADC value can provide valuable information in the differential diagnosis. (authors)

  2. COMPARISON OF THORACIC ULTRASONOGRAPHY AND RADIOGRAPHY FOR THE DETECTION OF INDUCED SMALL VOLUME PNEUMOTHORAX IN THE HORSE.

    Science.gov (United States)

    Partlow, Jessica; David, Florent; Hunt, Luanne Michelle; Relave, Fabien; Blond, Laurent; Pinilla, Manuel; Lavoie, Jean-Pierre

    2017-05-01

    Small volume pneumothorax can be challenging to diagnose in horses. The current standard method for diagnosis is standing thoracic radiography. We hypothesized that thoracic ultrasonography would be more sensitive. Objectives of this prospective, experimental study were to describe a thoracic ultrasound method for detection of small volume pneumothorax in horses and to compare results of radiography and ultrasound in a sample of horses with induced small volume pneumothorax. Six mature healthy horses were recruited for this study. For each horse, five 50 ml air boluses were sequentially introduced via a teat cannula into the pleural space. Lateral thoracic radiographs and standardized ultrasound (2D and M-mode) examinations of both hemithoraces were performed following administration of each 50 ml air bolus. Radiographs and ultrasound images/videos were analyzed for detection of pneumothorax by four independent investigators who were unaware of treatment status. Sensitivity, specificity, positive predictive values, negative predictive values, and agreement among investigators (Kappa test, κ) were calculated for radiography, 2D and M-mode ultrasound. Comparisons were made using a chi-squared exact test with significance set at P pneumothorax detection (P = 0.02 and P = 0.04, respectively). Specificity and positive predictive values were similar for all three imaging modalities (P = 1). Agreement between investigators for pneumothorax detection was excellent for 2D ultrasound (κ = 1), very good for M-mode ultrasound (κ = 0.87), and good for radiography (κ = 0.79). Findings from this experimental study supported the use of thoracic ultrasonography as a diagnostic method for detecting pneumothorax in horses. © 2017 American College of Veterinary Radiology.

  3. Is the presence of mammographic comedo calcification really a prognostic factor for small screen-detected invasive breast cancers?

    International Nuclear Information System (INIS)

    James, J.J.; Evans, A.J.; Pinder, S.E.; Macmillan, R.D.; Wilson, A.R.M.; Ellis, I.O.

    2003-01-01

    AIM: It has been suggested that the use of traditional prognostic factors such as histological grade and lymph node stage are not reliable predictors of outcome for small ( 2 = 9.68,P = 0.008). No significant association was demonstrated between the presence of comedo calcification and survival. Multivariate analysis confirmed lymph node stage as the only independent prognostic factor for these small screen-detected breast cancers (χ 2 = 7.18,P = 0.007). There were significant associations between the presence of comedo calcification on the screening mammogram and high histological grade and small tumour size. CONCLUSION: Although the overall outcome for small screen-detected breast cancers (<15 mm diameter) is excellent, the presence of lymph node metastases is associated with a significant reduction in long-term survival. The presence of mammographic comedo calcification is not an independent prognostic factor, but is closely related to histological grade. James, J. J. et al. (2003). Clinical Radiology, 58, 54-62

  4. Craft and Conservation: Features of Danish Journalism Culture

    DEFF Research Database (Denmark)

    Schultz, Ida

    This paper presents the field theory of Pierre Bourdieu, discusses how the framework can be used for studying journalism culture, and illustrates the use in a case study of journalism education in Denmark. The first section makes a first attempt to define Journalism Culture as a logic of practice...... of field, capital and habitus to identity craft as a strong capital in the field and conservation as a dominant logic....

  5. Application of CRAFT in two-dimensional NMR data processing.

    Science.gov (United States)

    Krishnamurthy, Krish; Sefler, Andrea M; Russell, David J

    2017-03-01

    Two-dimensional (2D) data are typically truncated in both dimensions, but invariably and severely so in the indirect dimension. These truncated FIDs and/or interferograms are extensively zero filled, and Fourier transformation of such zero-filled data is always preceded by a rapidly decaying apodization function. Hence, the frequency line width in the spectrum (at least parallel to the evolution dimension) is almost always dominated by the apodization function. Such apodization-driven line broadening in the indirect (t 1 ) dimension leads to the lack of clear resolution of cross peaks in the 2D spectrum. Time-domain analysis (i.e. extraction of frequency, amplitudes, line width, and phase parameters directly from the FID, in this case via Bayesian modeling into a tabular format) of NMR data is another approach for spectral resonance characterization and quantification. The recently published complete reduction to amplitude frequency table (CRAFT) technique converts the raw FID data (i.e. time-domain data) into a table of frequencies, amplitudes, decay rate constants, and phases. CRAFT analyses of time-domain data require minimal or no apodization prior to extraction of the four parameters. We used the CRAFT processing approach for the decimation of the interferograms and compared the results from a variety of 2D spectra against conventional processing with and without linear prediction. The results show that use of the CRAFT technique to decimate the t 1 interferograms yields much narrower spectral line width of the resonances, circumventing the loss of resolution due to apodization. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  6. A false-alarm aware methodology to develop robust and efficient multi-scale infrared small target detection algorithm

    Science.gov (United States)

    Moradi, Saed; Moallem, Payman; Sabahi, Mohamad Farzan

    2018-03-01

    False alarm rate and detection rate are still two contradictory metrics for infrared small target detection in an infrared search and track system (IRST), despite the development of new detection algorithms. In certain circumstances, not detecting true targets is more tolerable than detecting false items as true targets. Hence, considering background clutter and detector noise as the sources of the false alarm in an IRST system, in this paper, a false alarm aware methodology is presented to reduce false alarm rate while the detection rate remains undegraded. To this end, advantages and disadvantages of each detection algorithm are investigated and the sources of the false alarms are determined. Two target detection algorithms having independent false alarm sources are chosen in a way that the disadvantages of the one algorithm can be compensated by the advantages of the other one. In this work, multi-scale average absolute gray difference (AAGD) and Laplacian of point spread function (LoPSF) are utilized as the cornerstones of the desired algorithm of the proposed methodology. After presenting a conceptual model for the desired algorithm, it is implemented through the most straightforward mechanism. The desired algorithm effectively suppresses background clutter and eliminates detector noise. Also, since the input images are processed through just four different scales, the desired algorithm has good capability for real-time implementation. Simulation results in term of signal to clutter ratio and background suppression factor on real and simulated images prove the effectiveness and the performance of the proposed methodology. Since the desired algorithm was developed based on independent false alarm sources, our proposed methodology is expandable to any pair of detection algorithms which have different false alarm sources.

  7. Tracking Porters: Learning the Craft of Techno-Anthropology.

    Science.gov (United States)

    Bruun, Maja Hojer; Krause-Jensen, Jakob; Saltofte, Margit

    2015-01-01

    Anthropology attempts to gain insight into people's experiential life-worlds through long-term fieldwork. The quality of anthropological knowledge production, however, does not depend solely on the duration of the stay in the field, but also on a particular way of seeing social situations. The anthropological perspective is grounded in socio-cultural theory and forged by a distinct relativist or contextualist epistemological stance. The point is to understand events, concepts and phenomena from the insiders' point of view and to show how this view relates to the particular social and cultural context. In this chapter, we argue that although anthropology has its specific methodology - including a myriad of ethnographic data-gathering tools, techniques, analytical approaches and theories - it must first and foremost be understood as a craft. Anthropology as craft requires a specific 'anthropological sensibility' that differs from the standardized procedures of normal science. To establish our points we use an example of problem-based project work conducted by a group of Techno-Anthropology students at Aalborg University, we focus on key aspects of this craft and how the students began to learn it: For two weeks the students followed the work of a group of porters. Drawing on anthropological concepts and research strategies the students gained crucial insights about the potential effects of using tracking technologies in the hospital.

  8. Note: surface acoustic wave resonators for detecting of small changes of temperature: a thermometric "magnifying glass".

    Science.gov (United States)

    Kryshtal, R G; Medved, A V

    2014-02-01

    Application of surface acoustic wave resonators with a phase format of an output signal as the thermometric "magnifying glass" is suggested. Possibilities of monitoring and measuring of small changes of temperature from 0.001 K to 0.3 K of objects having thermal contact with the resonator's substrate are shown experimentally.

  9. Onboard Flow Sensing For Downwash Detection and Avoidance On Small Quadrotor Helicopters

    Science.gov (United States)

    2015-01-01

    onboard computers, one for flight stabilization and a Linux computer for sensor integration and control calculations . The Linux computer runs Robot...Hirokawa, D. Kubo , S. Suzuki, J. Meguro, and T. Suzuki. Small uav for immediate hazard map generation. In AIAA Infotech@Aerospace Conf, May 2007. 8F

  10. Detecting small lung tumors in mouse models by refractive-index microradiology

    Energy Technology Data Exchange (ETDEWEB)

    Chien, Chia-Chi; Hwu, Y. [Academia Sinica, Institute of Physics, Taipei (China); National Tsing Hua University, Department of Engineering and System Science, Hsinchu (China); Zhang, Guilin; Yue, Weisheng; Li, Yan; Xue, Hongjie [Chinese Academy of Sciences, Shanghai Institute of Applied Physics, Shanghai (China); Liu, Ping; Sun, Jianqi; Xu, Lisa X. [Shanghai Jiao Tong University, Shanghai (China); Wang, Chang Hai; Chen, Nanyow; Lu, Chien Hung; Lee, Ting-Kuo [Academia Sinica, Institute of Physics, Taipei (China); Yang, Yuh-Cheng; Lu, Yen-Ta [Mackay Memorial Hospital, Taipei City (China); Ching, Yu-Tai [National Chiao Tung University, Department of Computer Science, Hsinchu (China); Shih, T.F.; Yang, P.C. [National Taiwan University, College of Medicine, Taipei (China); Je, J.H. [Pohang University of Science and Technology Pohang, X-ray Imaging Center, Pohang CT, Kyungbuk (Korea, Republic of); Margaritondo, G. [Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne (Switzerland)

    2011-08-15

    Refractive-index (phase-contrast) radiology was able to detect lung tumors less than 1 mm in live mice. Significant micromorphology differences were observed in the microradiographs between normal, inflamed, and lung cancer tissues. This was made possible by the high phase contrast and by the fast image taking that reduces the motion blur. The detection of cancer and inflammation areas by phase contrast microradiology and microtomography was validated by bioluminescence and histopathological analysis. The smallest tumor detected is less than 1 mm{sup 3} with accuracy better than 1 x 10{sup -3} mm{sup 3}. This level of performance is currently suitable for animal studies, while further developments are required for clinical application. (orig.)

  11. Detecting small lung tumors in mouse models by refractive-index microradiology

    International Nuclear Information System (INIS)

    Chien, Chia-Chi; Hwu, Y.; Zhang, Guilin; Yue, Weisheng; Li, Yan; Xue, Hongjie; Liu, Ping; Sun, Jianqi; Xu, Lisa X.; Wang, Chang Hai; Chen, Nanyow; Lu, Chien Hung; Lee, Ting-Kuo; Yang, Yuh-Cheng; Lu, Yen-Ta; Ching, Yu-Tai; Shih, T.F.; Yang, P.C.; Je, J.H.; Margaritondo, G.

    2011-01-01

    Refractive-index (phase-contrast) radiology was able to detect lung tumors less than 1 mm in live mice. Significant micromorphology differences were observed in the microradiographs between normal, inflamed, and lung cancer tissues. This was made possible by the high phase contrast and by the fast image taking that reduces the motion blur. The detection of cancer and inflammation areas by phase contrast microradiology and microtomography was validated by bioluminescence and histopathological analysis. The smallest tumor detected is less than 1 mm 3 with accuracy better than 1 x 10 -3 mm 3 . This level of performance is currently suitable for animal studies, while further developments are required for clinical application. (orig.)

  12. Diagnosis of Wing Icing Through Lift and Drag Coefficient Change Detection for Small Unmanned Aircraft

    DEFF Research Database (Denmark)

    Sørensen, Kim Lynge; Blanke, Mogens; Johansen, Tor Arne

    2015-01-01

    This paper address the issue of structural change, caused by ice accretion, on UAVs by utilising a Neyman Pearson (NP) based statistical change detection approach, for the identification of structural changes of fixed wing UAV airfoils. A structural analysis is performed on the nonlinear aircraft...

  13. Detection and analysis of accident black spots with even small accident figures.

    NARCIS (Netherlands)

    Oppe, S.

    1982-01-01

    Accident black spots are usually defined as road locations with high accident potentials. In order to detect such hazardous locations we have to know the probability of an accident for a traffic situation of some kind, or the mean number of accidents for some unit of time. In almost all procedures

  14. Detection of small surface vessels in near, medium, and far infrared spectral bands

    Science.gov (United States)

    Dulski, R.; Milewski, S.; Kastek, M.; Trzaskawka, P.; Szustakowski, M.; Ciurapinski, W.; Zyczkowski, M.

    2011-11-01

    Protection of naval bases and harbors requires close co-operation between security and access control systems covering land areas and those monitoring sea approach routes. The typical location of naval bases and harbors - usually next to a large city - makes it difficult to detect and identify a threat in the dense regular traffic of various sea vessels (i.e. merchant ships, fishing boats, tourist ships). Due to the properties of vessel control systems, such as AIS (Automatic Identification System), and the effectiveness of radar and optoelectronic systems against different targets it seems that fast motor boats called RIB (Rigid Inflatable Boat) could be the most serious threat to ships and harbor infrastructure. In the paper the process and conditions for the detection and identification of high-speed boats in the areas of ports and naval bases in the near, medium and far infrared is presented. Based on the results of measurements and recorded thermal images the actual temperature contrast delta T (RIB / sea) will be determined, which will further allow to specify the theoretical ranges of detection and identification of the RIB-type targets for an operating security system. The data will also help to determine the possible advantages of image fusion where the component images are taken in different spectral ranges. This will increase the probability of identifying the object by the multi-sensor security system equipped additionally with the appropriate algorithms for detecting, tracking and performing the fusion of images from the visible and infrared cameras.

  15. Spatial filtering velocimetry revisited: exact short-time detecting schemes from arbitrarily small-size reticles

    International Nuclear Information System (INIS)

    Ando, S; Nara, T; Kurihara, T

    2014-01-01

    Spatial filtering velocimetry was proposed in 1963 by Ator as a velocity-sensing technique for aerial camera-control systems. The total intensity of a moving surface is observed through a set of parallel-slit reticles, resulting in a narrow-band temporal signal whose frequency is directly proportional to the image velocity. However, even despite its historical importance and inherent technical advantages, the mathematical formulation of this technique is only valid when infinite-length observation in both space and time is possible, which causes significant errors in most applications where a small receptive window and high resolution in both axes are desired. In this study, we apply a novel mathematical technique, the weighted integral method, to solve this problem, and obtain exact sensing schemes and algorithms for finite (arbitrarily small but non-zero) size reticles and short-time estimation. Practical considerations for utilizing these schemes are also explored both theoretically and experimentally. (paper)

  16. The Accuracy of Point-of-Care Ultrasound in Detecting Small Bowel Obstruction in Emergency Department

    Directory of Open Access Journals (Sweden)

    A. Pourmand

    2018-01-01

    Full Text Available Radiological imaging plays an essential role in the evaluation of a patient with suspected small bowel obstruction (SBO. In a few studies, point-of-care ultrasound (POCUS has been utilized as a primary imaging modality in patients with suspected SBO. POCUS has been shown to be an accurate tool in the diagnosis of SBO with multiple research studies noting a consistent high sensitivity with a range of 94–100% and specificity of 81–100%. Specific sonographic findings that increase the likelihood of SBO include dilatation of small bowel loops > 25 mm, altered intestinal peristalsis, increased thickness of the bowel wall, and intraperitoneal fluid accumulation. Studies also reported that emergency physicians could apply this technique with limited and short-term ultrasound training. In this article, we aim to review the sensitivity and specificity of ultrasound examinations performed by emergency physicians in patients with suspected SBO.

  17. Detection of unsuspected colonic abnormalities using the pneumocolon technique during small bowel meal examination

    International Nuclear Information System (INIS)

    Chou, S.; Skehan, S.J.; Brown, A.L.; Rawlinson, J.; Somers, S.

    2000-01-01

    AIMS: The pneumocolon technique in small bowel meal examination is used to obtain double-contrast views of the distal ileum. The purpose of this study was to determine the proportion of cases in which an overhead pneumocolon radiograph demonstrated clinically relevant findings in the colon. METHODS: The overhead pneumocolon radiographs in 151 patients who underwent small bowel meals were evaluated retrospectively. A chart review was performed on those patients with positive colonic findings to determine if the suspected abnormalities affected patient management. RESULTS: Colonic abnormalities were identified in 34 of the 151 patients. One patient had a previously undiagnosed ascending colonic cancer; 17 had evidence of acute or chronic colitis; 13 had diverticulosis; one had a caecal polyp; one had an ileosigmoid fistula; one had a filling defect in the ascending colon. In 25 cases the colonic abnormality was visible only on the pneumocolon radiograph and not on the preceding single-contrast images. Management was altered by the colonic findings in seven cases. False-positive findings occurred in two cases. CONCLUSIONS: A routine overhead radiograph following use of the pneumocolon technique is a useful adjunct to small bowel meal examination as it can yield unsuspected and clinically significant colonic findings. Chou, S. (2000)

  18. Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering.

    Directory of Open Access Journals (Sweden)

    Bo Zhang-Haagen

    Full Text Available Small proteins like amyloid beta (Aβ monomers are related to neurodegenerative disorders by aggregation to insoluble fibrils. Small angle neutron scattering (SANS is a nondestructive method to observe the aggregation process in solution. We show that SANS is able to resolve monomers of small molecular weight like Aβ for aggregation studies. We examine Aβ monomers after prolonged storing in d-hexafluoroisopropanol (dHFIP by using SANS and dynamic light scattering (DLS. We determined the radius of gyration from SANS as 1.0±0.1 nm for Aβ1-40 and 1.6±0.1 nm for Aβ1-42 in agreement with 3D NMR structures in similar solvents suggesting a solvent surface layer with 5% increased density. After initial dissolution in dHFIP Aβ aggregates sediment with a major component of pure monomers showing a hydrodynamic radius of 1.8±0.3 nm for Aβ1-40 and 3.2±0.4 nm for Aβ1-42 including a surface layer of dHFIP solvent molecules.

  19. Computer-aided detection of small pulmonary nodules in multidetector spiral computed tomography (MSCT) in children

    International Nuclear Information System (INIS)

    Honnef, D.; Behrendt, F.F.; Hohl, C.; Mahnken, A.H.; Guenther, R.W.; Das, M.; Mertens, R.; Stanzel, S.

    2008-01-01

    Purpose: Retrospective evaluation of computer-aided detection software (CAD) for automated detection (LungCAD, Siemens Medical solutions, Forchheim, Germany) and volumetry (LungCARE) of pulmonary nodules in dose-reduced pediatric MDCT. Materials and Methods: 30 scans of 24 children (10.4±5.9 years, 13 girls, 11 boys, 39.7±29.3 kg body weight) were performed on a 16-MDCT for tumor staging (n=18), inflammation (n=9), other indications (n=3). Tube voltage 120 kVp and effective mAs were adapted to body weight. Slice thickness 2 mm, increment 1 mm. A pediatric radiologist (U1), a CAD expert (U2) and an inexperienced radiologist (U3) independently analyzed the lung window images without and with the CAD as a second reader. In a consensus decision U1 and U2 were the reference standard. Results: Five examinations had to be excluded from the study due to other underlying lung disease. A total of 24 pulmonary nodules were found in all data sets with a minimal diameter of 0.35 mm to 3.81 mm (mean 1.7±0.85 mm). The sensitivities were as follows: U1 95.8% and 100% with CAD; U2 91.7% U3 66.7%. U2 and U3 did not detect further nodules with CAD. The sensitivity of CAD alone was 41.7% with 0.32 false-positive findings per examination. Interobserver agreement between U1/U2 regarding nodule detection with CAD was good (k=0.6500) and without CAD very good (k=0.8727). For the rest (U1/U3; U2/U3 with and without CAD), it was weak (k=0.0667-0.1884). Depending on the measured value (axial measurement, volume), there is a significant correlation (p=0.0026-0.0432) between nodule size and CAD detection. Undetected pulmonary nodules (mean 1.35 mm; range 0.35-2.61 mm) were smaller than the detected ones (mean 2.19 mm; range 1.35-3.81 mm). No significant correlation was found between CAD findings and patient age (p=0.9263) and body weight (p=0.9271) as well as nodule location (subpleural, intraparenchymal; p=1.0) and noise/SNR. (orig.)

  20. Development and Positioning of the Collective Product of Slovenian Craft Trademark

    Directory of Open Access Journals (Sweden)

    Adrijana Poljanšek

    2017-09-01

    Full Text Available The new collective trademark Izdelek slovenske obrti (hereinafter: PSC; English: Product of Slovenian Craft was launched on the market in 2014. The initiative for the trademark was provided by the Textile Section at the Chamber of Craft and Small Business of Slovenia (hereinafter: the OZS, which also registered the trademark. Members of the OZS have the right to obtain and use the trademark, and to use it to promote their products or services. After two years, only a small number of section members use the trademark. Because the section would like to see an increased number of members use the trademark, research regarding the latter was carried out. The results are presented in this article. The descriptive course of development and registration of the collective trademark PSC is presented in the first part of our research. In the second part, questionnaires were drafted for collective trademark PSC users, potential users and consumers. The results obtained using three questionnaires were analysed using a SWOT analysis. Based on the results, it was determined that the trademark has not yet been properly positioned on the Slovenian market. Advantages include the familiarity of Textile Section members with the trademark, and their eagerness to use it. One disadvantage is the trademark’s current lack of recognition among consumers. For this reason, section members who are also potential users of the trademark do not give it priority and therefore do not opt to use it. The following will impact the trademark’s recognition among consumers: innovative marketing campaigns, the inclusion of the media and social networks, the improved recognition and visibility of the logotype, and an effective and pervasive slogan, as was determined in our research.

  1. The additional value of the lateral chest radiograph for the detection of small pulmonary nodules-a ROC analysis.

    Science.gov (United States)

    Kluthke, Robin Alexander; Kickuth, Ralph; Bansmann, Paul Martin; Tüshaus, Carolin; Adams, Stephan; Liermann, Dieter; Kirchner, Johannes

    2016-11-01

    For the past 30 years, many authors have described different advantages of the use of the additional lateral chest radiograph. However, some radiologic departments gave up performing the lateral view recently. A potential reason for this might be a lack of evidence for any diagnostic benefit of the additional lateral view of the thorax in recent studies. The objective of this study was to evaluate the diagnostic benefit of the additional lateral view for the detection of small pulmonary nodules compared with CT examinations as a gold standard. The patient population consisted of 45 patients with SPN and 45 patients without SPN. Four radiologists with varying experience in the assessment of thoracic imaging first examined the sole posteroanterior (PA) projection. After a few days, they were instructed to examine the PA and the additional lateral view. A receiver-operating characteristic analysis was accomplished to compare the documented results. The mean Az value of the sole PA view was 0.75 and 0.77 by the combination of PA and additional lateral view. So, there was no significant difference between the detectable Az values (Δ = 0.02; p = 0.384). With a cut-off value of >3, the additional view even reduced the sensitivity by averaging to 5.6%. The decrease of sensitivity by using the additional view was most detectable within the group of more experienced radiologists. The additional lateral view of the chest provides no diagnostic benefit in the detection of small pulmonary nodules in comparison with the sole PA projection. Nevertheless, the results of the present study must not be understood as a general evaluation of the benefits of the lateral radiograph per se, because we did not examine other relevant issues (i.e. cardiac failure, lung parenchyma diseases or abnormalities in hilar anatomy). Advances in knowledge: Our study demonstrates a lack of evidence for any diagnostic benefit of the additional lateral view of the thorax in detecting SPN.

  2. SMC SMP 24: A newly radio-detected planetary nebula in the small Magellanic cloud

    Directory of Open Access Journals (Sweden)

    Bojičić I.S.

    2010-01-01

    Full Text Available In this paper we report a new radio-continuum detection of an extragalactic planetary nebula (PN: SMC SMP 24. We show the radio-continuum image of this PN and present the measured radio data. The newly reduced radio observations are consistent with the multi-wavelength data and derived parameters found in the literature. SMC SMP 24 appears to be a young and compact PN, optically thick at frequencies below 2 GHz.

  3. SMC SMP 24: A Newly Radio-Detected Planetary Nebula in the Small Magellanic Cloud

    Directory of Open Access Journals (Sweden)

    Bojicic, I. S.

    2010-12-01

    Full Text Available In this paper we report a new radio-continuum detection of an extragalactic planetary nebula (PN: SMC~SMP~24. We show the radio-continuum image of this PN and present the measured radio data. The newly reduced radio observations are consistent with the multi-wavelength data and derived parameters found in the literature. SMC~SMP~24 appears to be a young and compact PN, optically thick at frequencies below 2~GHz.

  4. Generation of Small Single Domain Nanobody Binders for Sensitive Detection of Testosterone by Electrochemical Impedance Spectroscopy.

    Science.gov (United States)

    Li, Guanghui; Zhu, Min; Ma, Lu; Yan, Junrong; Lu, Xiaoling; Shen, Yanfei; Wan, Yakun

    2016-06-08

    A phage display library of variable domain of the heavy chain only antibody or nanobody (Nb) was constructed after immunizing a bactrian camel with testosterone. With the smaller molecular size (15 kDa), improved solubility, good stability, high affinity, specificity, and lower immunogenicity, Nbs are a promising tool in the next generation of diagnosis and medical applications. Testosterone is a reproductive hormone, playing an important role in normal cardiac function and being the highly predictive marker for many diseases. Herein, a simple and sensitive immunosensor based on electrochemical impedance spectroscopy (EIS) and Nbs was successfully developed for the determination of testosterone. We successfully isolated the antitestosterone Nbs from an immune phage display library. Moreover, one of the Nbs was biotinylated according to in vivo BirA system, which showed the highest production yield and the most stable case. Further, the EIS immunosensor was set up for testosterone detection by applying the biotinylated antitestosterone Nb. As a result, the biosensor exhibited a linear working range from 0.05 to 5 ng mL(-1) with a detection limit of 0.045 ng mL(-1). In addition, the proposed immunosensor was successfully applied in determining testosterone in serum samples. In conclusion, the proposed immunosensor revealed high specificity of testosterone detection and showed as a potential approach for sensitive and accurate diagnosis of testosterone.

  5. Economic Analysis of Alternative Strategies for Detection of ALK Rearrangements in Non Small Cell Lung Cancer.

    Science.gov (United States)

    Doshi, Shivang; Ray, David; Stein, Karen; Zhang, Jie; Koduru, Prasad; Fogt, Franz; Wellman, Axel; Wat, Ricky; Mathews, Charles

    2016-01-06

    Identification of alterations in ALK gene and development of ALK-directed therapies have increased the need for accurate and efficient detection methodologies. To date, research has focused on the concordance between the two most commonly used technologies, fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC). However, inter-test concordance reflects only one, albeit important, aspect of the diagnostic process; laboratories, hospitals, and payors must understand the cost and workflow of ALK rearrangement detection strategies. Through literature review combined with interviews of pathologists and laboratory directors in the U.S. and Europe, a cost-impact model was developed that compared four alternative testing strategies-IHC only, FISH only, IHC pre-screen followed by FISH confirmation, and parallel testing by both IHC and FISH. Interviews were focused on costs of reagents, consumables, equipment, and personnel. The resulting model showed that testing by IHC alone cost less ($90.07 in the U.S., $68.69 in Europe) than either independent or parallel testing by both FISH and IHC ($441.85 in the U.S. and $279.46 in Europe). The strategies differed in cost of execution, turnaround time, reimbursement, and number of positive results detected, suggesting that laboratories must weigh the costs and the clinical benefit of available ALK testing strategies.

  6. Economic Analysis of Alternative Strategies for Detection of ALK Rearrangements in Non Small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Shivang Doshi

    2016-01-01

    Full Text Available Identification of alterations in ALK gene and development of ALK-directed therapies have increased the need for accurate and efficient detection methodologies. To date, research has focused on the concordance between the two most commonly used technologies, fluorescent in situ hybridization (FISH and immunohistochemistry (IHC. However, inter-test concordance reflects only one, albeit important, aspect of the diagnostic process; laboratories, hospitals, and payors must understand the cost and workflow of ALK rearrangement detection strategies. Through literature review combined with interviews of pathologists and laboratory directors in the U.S. and Europe, a cost-impact model was developed that compared four alternative testing strategies—IHC only, FISH only, IHC pre-screen followed by FISH confirmation, and parallel testing by both IHC and FISH. Interviews were focused on costs of reagents, consumables, equipment, and personnel. The resulting model showed that testing by IHC alone cost less ($90.07 in the U.S., $68.69 in Europe than either independent or parallel testing by both FISH and IHC ($441.85 in the U.S. and $279.46 in Europe. The strategies differed in cost of execution, turnaround time, reimbursement, and number of positive results detected, suggesting that laboratories must weigh the costs and the clinical benefit of available ALK testing strategies.

  7. Detection of small human cerebral cortical lesions with MRI under different levels of Gaussian smoothing: applications in epilepsy

    Science.gov (United States)

    Cantor-Rivera, Diego; Goubran, Maged; Kraguljac, Alan; Bartha, Robert; Peters, Terry

    2010-03-01

    The main objective of this study was to assess the effect of smoothing filter selection in Voxel-Based Morphometry studies on structural T1-weighted magnetic resonance images. Gaussian filters of 4 mm, 8 mm or 10 mm Full Width at High Maximum are commonly used, based on the assumption that the filter size should be at least twice the voxel size to obtain robust statistical results. The hypothesis of the presented work was that the selection of the smoothing filter influenced the detectability of small lesions in the brain. Mesial Temporal Sclerosis associated to Epilepsy was used as the case to demonstrate this effect. Twenty T1-weighted MRIs from the BrainWeb database were selected. A small phantom lesion was placed in the amygdala, hippocampus, or parahippocampal gyrus of ten of the images. Subsequently the images were registered to the ICBM/MNI space. After grey matter segmentation, a T-test was carried out to compare each image containing a phantom lesion with the rest of the images in the set. For each lesion the T-test was repeated with different Gaussian filter sizes. Voxel-Based Morphometry detected some of the phantom lesions. Of the three parameters considered: location,size, and intensity; it was shown that location is the dominant factor for the detection of the lesions.

  8. Energy spectrum of iron nuclei measured inside the MIR space craft using CR-39 track detectors

    International Nuclear Information System (INIS)

    Guenther, W.; Leugner, D.; Becker, E.; Flesch, F.; Heinrich, W.; Huentrup, G.; Reitz, G.; Roecher, H.; Streibel, T.

    1999-01-01

    We have exposed stacks of CR-39 plastic nuclear track detectors inside the MIR space craft during the EUROMIR95 space mission for almost 6 months. Over this long period a large number of tracks of high LET events was accumulated in the detector foils. The etching and measuring conditions for this experiment were optimized to detect tracks of stopping iron nuclei. We found 185 stopping iron nuclei inside the stack and identified their trajectories through the material of the experiment. Based on the energy-range relation the energy at the surface of the stack was determined. These particles allow the determination of the low energy part of the spectrum of iron nuclei behind shielding material inside the MIR station

  9. Accuracy of the double contrast technique in the detection of small lesions of the colon

    Energy Technology Data Exchange (ETDEWEB)

    Muzzio, P C; Pomerri, F; Feltrin, G P; Biondetti, P R; Di Maggio, C [Padua Univ. (Italy). Istituto di Radiologia e Fisioterapia

    1979-02-01

    Double contrast enema has become an indispensible aid in early lesions of the colon, in particular for small lesions. According to the authors' opinion, the method provides so much additional information that it ought to be applied at all rates in such cases. It is neither expensive nor time-consuming and can easily be carried out in any X-ray department, especially where a fibroscope is not available. The results are reliable if the technique is applied correctly, if the patient is well-prepared, and if the radiologist has enough technical and semiological experience.

  10. Detection and control of potential core damage during a small-break LOCA

    International Nuclear Information System (INIS)

    Thomas, G.R.; Zebroski, E.L.

    1981-01-01

    A refreshing development in small-break LOCA analysis and testing is the recognition that this work can be of real value to a plant operator. Event-trees, or safety sequence diagrams, are being made increasingly realistic and are being used to develop and to test the abnormal transient operating guidelines (ATOGs) which provide a basis for operator response, training, and simulator work now under way. Perhaps the most monumental lesson of the TMI-2 accident is that the tradition of extreme worst-case analysis and data gathering can provide a directly negative contribution to safety if it is used as the basis for designing procedures and training of operator response. The event-trees for guiding operator response to abnormal conditions, ATOGs, must be based on physically realistic, best-estimate models. Possibly, the most dramatic risk reduction achieved will be attained through the use of realistic accident analysis, which leads to realistic operator guidelines and training, improved display of the critical information to the operator, and improved management structure. Given the dominant contribution of small-break LOCAs to the overall public risk envelope, realism should be the primary banner for future work in this field

  11. Detection of quantitative trait loci causing abnormal spermatogenesis and reduced testis weight in the small testis (Smt) mutant mouse.

    Science.gov (United States)

    Bolor, Hasbaira; Wakasugi, Noboru; Zhao, Wei Dong; Ishikawa, Akira

    2006-04-01

    The small testis (Smt) mutant mouse is characterized by a small testis of one third to one half the size of a normal testis, and its spermatogenesis is mostly arrested at early stages of meiosis, although a small number of spermatocytes at the late prophase of meiosis and a few spermatids can sometimes be seen. We performed quantitative trait locus (QTL) analysis of these spermatogenic traits and testis weight using 221 F2 males obtained from a cross between Smt and MOM (Mus musculus molossinus) mice. At the genome-wide 5% level, we detected two QTLs affecting meiosis on chromosomes 4 and 13, and two QTLs for paired testis weight as a percentage of body weight on chromosomes 4 and X. In addition, we found several QTLs for degenerated germ cells and multinuclear giant cells on chromosomes 4, 7 and 13. Interestingly, for cell degeneration, the QTL on chromosome 13 interacted epistatically with the QTL on chromosome 4. These results reveal polygenic participation in the abnormal spermatogenesis and small testis size in the Smt mutant.

  12. SEARCH FOR MICROORGANISMS IN UTENSILS, MILK AND CHEESE OF THE CRAFT PRODUCTION IN SMALL UNITS OF PRODUCTION IN SEROPÉDICA, RIO DE JANEIRO PESQUISA DE MICRORGANISMOS EM UTENSÍLIOS, LEITE E QUEIJOS DE PRODUÇÃO ARTESANAL EM UNIDADES DE PRODUÇÃO FAMILIAR NO MUNICÍPIO DE SEROPÉDICA, RIO DE JANEIRO.

    Directory of Open Access Journals (Sweden)

    Paulo de Tarso Landgraf Botteon

    2009-04-01

    Full Text Available This work was performed in order to evaluate the hygienical and sanitary features of homemade production of “Minas Frescal” cheese in small units of production in Seropédica, RJ. Samples of subclinical and clinical mastitic cows milk, production stuffs and cheese were analyzed. Several microorganisms were detected in 100% of the samples, including Salmonella spp. in a sample of cheese. The main isolated agents were Escherichia coli, Staphylococcus aureus, Staphylococcus schleiferi coagulans, Staphylococcus spp., Enterobacter spp., Enterobacter aerogenes, Bacillus spp., Klebsiella pneumoniae, Streptococcus uberis, Streptococcus spp. and Micrococcus spp. Microorganisms were isolated from the milk of clinical and subclinical mastitis cows, the production stuffs and storage and also from the cheese, confirming the inadequate thermic treatment and hygienic procedures of the utensils. The inadequate hygienic quality of the homemade cheese evaluated is of concern once the isolated microorganisms represent potential hazards to health and the product sale is direct to the consumers.

    KEY WORDS: Food safety, homemade cheese, hygienic quality.
    Este trabalho foi desenvolvido para avaliar aspectos higiênico-sanitários da produção artesanal de queijo minas frescal em pequenas unidades de produção em um assentamento de reforma agrária em Seropédica, RJ. Analisaram-se amostras de leite, queijo e utensílios utilizados em diferentes etapas da linha de produção. Verificou-se a presença de microrganismos diversos, incluindo-se Salmonella spp. em uma amostra de queijo. Os principais agentes isolados foram Escherichia coli, Staphylococcus aureus, Staphylococcus schleiferi coagulans, Staphylococcus spp., Enterobacter spp., Enterobacter aerogenes, Bacillus spp, Klebsiella pneumoniae, Streptococcus uberis, Streptococcus spp. e Micrococcus spp. Isolaram-se microrganismos de quartos mamários de vacas com mastite clínica ou subcl

  13. Targeted histology sampling from atypical small acinar proliferation area detected by repeat transrectal prostate biopsy

    Directory of Open Access Journals (Sweden)

    A. V. Karman

    2017-01-01

    Full Text Available Оbjective: to define the approach to the management of patients with the detected ASAP area.Materials and methods. In the time period from 2012 through 2015, 494 patients with previously negative biopsy and remaining suspicion of prostate cancer (PCa were examined. The patients underwent repeat 24-core multifocal prostate biopsy with taking additional tissue samples from suspicious areas detected by multiparametric magnetic resonance imaging and transrectal ultrasound. An isolated ASAP area was found in 127 (25. 7 % of the 494 examined men. All of them were offered to perform repeat target transrectal biopsy of this area. Targeted transrectal ultrasound guided biopsy of the ASAP area was performed in 56 (44.1 % of the 127 patients, 53 of them being included in the final analysis.Results. PCa was diagnosed in 14 (26.4 % of the 53 patients, their mean age being 64.4 ± 6.9 years. The average level of prostate-specific antigen (PSA in PCa patients was 6.8 ± 3.0 ng/ml, in those with benign lesions – 9.3 ± 6.5 ng/ml; the percentage ratio of free/total PSA with PCa was 16.2 ± 7,8 %, with benign lesions – 23.3 ± 7.7 %; PSA density in PCa patients was 0.14 ± 0.07 ng/ml/cm3, in those with benign lesions – 0.15 ± 0.12 ng/ml/cm3. Therefore, with ASAP area being detected in repeat prostate biopsy samples, it is advisable that targeted extended biopsy of this area be performed. 

  14. Environmental Support to Amphibious Craft, Patrol Boats, and Coastal Ships: An Annotated Bibliography

    National Research Council Canada - National Science Library

    Bachmann, Charles M; Fusina, Robert A; Nichols, C. R; McDermid, Jack

    2008-01-01

    This annotated bibliography is a selection of citations to books, articles, documents, and data bases highlighting environmental conditions that impact the safety and performance of amphibious craft...

  15. Can we use PCA to detect small signals in noisy data?

    Science.gov (United States)

    Spiegelberg, Jakob; Rusz, Ján

    2017-01-01

    Principal component analysis (PCA) is among the most commonly applied dimension reduction techniques suitable to denoise data. Focusing on its limitations to detect low variance signals in noisy data, we discuss how statistical and systematical errors occur in PCA reconstructed data as a function of the size of the data set, which extends the work of Lichtert and Verbeeck, (2013) [16]. Particular attention is directed towards the estimation of bias introduced by PCA and its influence on experiment design. Aiming at the denoising of large matrices, nullspace based denoising (NBD) is introduced. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Computer-aided detection (CAD) of lung nodules and small tumours on chest radiographs

    International Nuclear Information System (INIS)

    De Boo, D.W.; Prokop, M.; Uffmann, M.; Ginneken, B. van; Schaefer-Prokop, C.M.

    2009-01-01

    Detection of focal pulmonary lesions is limited by quantum and anatomic noise and highly influenced by variable perception capacity of the reader. Multiple studies have proven that lesions - missed at time of primary interpretation - were visible on the chest radiographs in retrospect. Computer-aided diagnosis (CAD) schemes do not alter the anatomic noise but aim at decreasing the intrinsic limitations and variations of human perception by alerting the reader to suspicious areas in a chest radiograph when used as a 'second reader'. Multiple studies have shown that the detection performance can be improved using CAD especially for less experienced readers at a variable amount of decreased specificity. There seem to be a substantial learning process for both, experienced and inexperienced readers, to be able to optimally differentiate between false positive and true positive lesions and to build up sufficient trust in the capabilities of these systems to be able to use them at their full advantage. Studies so far focussed on stand-alone performance of the CAD schemes to reveal the magnitude of potential impact or on retrospective evaluation of CAD as a second reader for selected study groups. Further research is needed to assess the performance of these systems in clinical routine and to determine the trade-off between performance increase in terms of increased sensitivity and decreased inter-reader variability and loss of specificity and secondary indicated follow-up examinations for further diagnostic workup.

  17. Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

    Science.gov (United States)

    Best, Myron G; Sol, Nik; In 't Veld, Sjors G J G; Vancura, Adrienne; Muller, Mirte; Niemeijer, Anna-Larissa N; Fejes, Aniko V; Tjon Kon Fat, Lee-Ann; Huis In 't Veld, Anna E; Leurs, Cyra; Le Large, Tessa Y; Meijer, Laura L; Kooi, Irsan E; Rustenburg, François; Schellen, Pepijn; Verschueren, Heleen; Post, Edward; Wedekind, Laurine E; Bracht, Jillian; Esenkbrink, Michelle; Wils, Leon; Favaro, Francesca; Schoonhoven, Jilian D; Tannous, Jihane; Meijers-Heijboer, Hanne; Kazemier, Geert; Giovannetti, Elisa; Reijneveld, Jaap C; Idema, Sander; Killestein, Joep; Heger, Michal; de Jager, Saskia C; Urbanus, Rolf T; Hoefer, Imo E; Pasterkamp, Gerard; Mannhalter, Christine; Gomez-Arroyo, Jose; Bogaard, Harm-Jan; Noske, David P; Vandertop, W Peter; van den Broek, Daan; Ylstra, Bauke; Nilsson, R Jonas A; Wesseling, Pieter; Karachaliou, Niki; Rosell, Rafael; Lee-Lewandrowski, Elizabeth; Lewandrowski, Kent B; Tannous, Bakhos A; de Langen, Adrianus J; Smit, Egbert F; van den Heuvel, Michel M; Wurdinger, Thomas

    2017-08-14

    Blood-based liquid biopsies, including tumor-educated blood platelets (TEPs), have emerged as promising biomarker sources for non-invasive detection of cancer. Here we demonstrate that particle-swarm optimization (PSO)-enhanced algorithms enable efficient selection of RNA biomarker panels from platelet RNA-sequencing libraries (n = 779). This resulted in accurate TEP-based detection of early- and late-stage non-small-cell lung cancer (n = 518 late-stage validation cohort, accuracy, 88%; AUC, 0.94; 95% CI, 0.92-0.96; p swarm intelligence may also benefit the optimization of diagnostics readout of other liquid biopsy biosources. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Chromogenic in situ hybridisation (CISH) is a powerful method to detect ALK-positive non-small cell lung carcinomas.

    Science.gov (United States)

    Wagner, F; Streubel, A; Roth, A; Stephan-Falkenau, S; Mairinger, T

    2014-05-01

    We assessed the potential of a chromogenic in situ hybridisation (CISH) assay in comparison with quantitative reverse transcription (RT)-PCR (qPCR) to detect anaplastic lymphoma kinase (ALK) break apart-positive lung carcinomas. Dual-colour CISH using a break apart probe for the ALK gene on 2p23 was performed with 181 formalin-fixed, paraffin-embedded tissue and agar block sections from 175 cases of non-small cell lung carcinomas (NSCLC). Stained slides were analysed with a standard bright-field microscope at 1000× magnification by counting signals from 60 non-overlapping nuclei from three different tumour areas. Samples with ≥15% of positive nuclei were judged as ALK break apart-positive. All samples were simultaneously analysed by qPCR for EML4-ALK to validate CISH results, and positive samples were subject to Sanger sequencing. CISH was successful with 173 of 181 hybridised samples (96%), and seven ALK break apart-positive cases were detected. CISH signals were specific and distinct for both colours. All positive cases were confirmed by qPCR and Sanger sequencing, and concordance between CISH and qPCR was 100%. Nearly all samples (9/10) which failed by qPCR were accessible to CISH analysis. CISH is a very reliable, convenient and inexpensive method to detect ALK-positive NSCLC. CISH success rate is comparably high as with qPCR, and it detects all ALK break apart events in a single assay. It is of special value when RNA quality is poor, or when small biopsies with a very limited amount of tumour cells have to be analysed.

  19. DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data.

    Science.gov (United States)

    Zhang, Yuanwei; Zang, Qiguang; Zhang, Huan; Ban, Rongjun; Yang, Yifan; Iqbal, Furhan; Li, Ao; Shi, Qinghua

    2016-07-08

    Small RNA (sRNA) Sequencing technology has revealed that microRNAs (miRNAs) are capable of exhibiting frequent variations from their canonical sequences, generating multiple variants: the isoforms of miRNAs (isomiRs). However, integrated tool to precisely detect and systematically annotate isomiRs from sRNA sequencing data is still in great demand. Here, we present an online tool, DeAnnIso (Detection and Annotation of IsomiRs from sRNA sequencing data). DeAnnIso can detect all the isomiRs in an uploaded sample, and can extract the differentially expressing isomiRs from paired or multiple samples. Once the isomiRs detection is accomplished, detailed annotation information, including isomiRs expression, isomiRs classification, SNPs in miRNAs and tissue specific isomiR expression are provided to users. Furthermore, DeAnnIso provides a comprehensive module of target analysis and enrichment analysis for the selected isomiRs. Taken together, DeAnnIso is convenient for users to screen for isomiRs of their interest and useful for further functional studies. The server is implemented in PHP + Perl + R and available to all users for free at: http://mcg.ustc.edu.cn/bsc/deanniso/ and http://mcg2.ustc.edu.cn/bsc/deanniso/. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  20. Prospective comparison of MR imaging (1.5 T) and CT detection of small intracranial metastases

    International Nuclear Information System (INIS)

    Dowd, C.F.; Dillon, W.P.; Laxer, K.; Norman, D.; Newton, T.H.

    1987-01-01

    Prior studies indicate lack of MR imaging sensitivity in the evaluation of intractable seizure patients. The authors reviewed MR imaging studies of 15 patients with intractable seizures. High-quality thin-section multiplanar images were obtained with electrocardiographic gating and/or flow compensation techniques and a 1.5-T General Electric Signa unit. Correlation with intracranial electro-encephalography (EEG), CT, and pathology was obtained in all patients. Abnormalities on MR imaging were detected in all but one patient. Pathology revealed MTS in 12 of 15 patients. Other entities included heterotopias and cavernous angiomas. The authors' study indicates that high-resolution, flow-compensated MR imaging is quite sensitive for localization of eleptogenic structural abnormalities and complements EEG

  1. Small-target leak detection for a closed vessel via infrared image sequences

    Science.gov (United States)

    Zhao, Ling; Yang, Hongjiu

    2017-03-01

    This paper focus on a leak diagnosis and localization method based on infrared image sequences. Some problems on high probability of false warning and negative affect for marginal information are solved by leak detection. An experimental model is established for leak diagnosis and localization on infrared image sequences. The differential background prediction is presented to eliminate the negative affect of marginal information on test vessel based on a kernel regression method. A pipeline filter based on layering voting is designed to reduce probability of leak point false warning. A synthesize leak diagnosis and localization algorithm is proposed based on infrared image sequences. The effectiveness and potential are shown for developed techniques through experimental results.

  2. Event detection and localization for small mobile robots using reservoir computing.

    Science.gov (United States)

    Antonelo, E A; Schrauwen, B; Stroobandt, D

    2008-08-01

    Reservoir Computing (RC) techniques use a fixed (usually randomly created) recurrent neural network, or more generally any dynamic system, which operates at the edge of stability, where only a linear static readout output layer is trained by standard linear regression methods. In this work, RC is used for detecting complex events in autonomous robot navigation. This can be extended to robot localization tasks which are solely based on a few low-range, high-noise sensory data. The robot thus builds an implicit map of the environment (after learning) that is used for efficient localization by simply processing the input stream of distance sensors. These techniques are demonstrated in both a simple simulation environment and in the physically realistic Webots simulation of the commercially available e-puck robot, using several complex and even dynamic environments.

  3. Penguin head movement detected using small accelerometers: a proxy of prey encounter rate.

    Science.gov (United States)

    Kokubun, Nobuo; Kim, Jeong-Hoon; Shin, Hyoung-Chul; Naito, Yasuhiko; Takahashi, Akinori

    2011-11-15

    Determining temporal and spatial variation in feeding rates is essential for understanding the relationship between habitat features and the foraging behavior of top predators. In this study we examined the utility of head movement as a proxy of prey encounter rates in medium-sized Antarctic penguins, under the presumption that the birds should move their heads actively when they encounter and peck prey. A field study of free-ranging chinstrap and gentoo penguins was conducted at King George Island, Antarctica. Head movement was recorded using small accelerometers attached to the head, with simultaneous monitoring for prey encounter or body angle. The main prey was Antarctic krill (>99% in wet mass) for both species. Penguin head movement coincided with a slow change in body angle during dives. Active head movements were extracted using a high-pass filter (5 Hz acceleration signals) and the remaining acceleration peaks (higher than a threshold acceleration of 1.0 g) were counted. The timing of head movements coincided well with images of prey taken from the back-mounted cameras: head movement was recorded within ±2.5 s of a prey image on 89.1±16.1% (N=7 trips) of images. The number of head movements varied largely among dive bouts, suggesting large temporal variations in prey encounter rates. Our results show that head movement is an effective proxy of prey encounter, and we suggest that the method will be widely applicable for a variety of predators.

  4. [Detection of small for gestational age fetuses during third trimester ultrasound. A monocentric observational study].

    Science.gov (United States)

    Peyronnet, V; Kayem, G; Mandelbrot, L; Sibiude, J

    2016-09-01

    Fetus small for gestational age (SGA) screening rate is evaluated around 21,7 % in France. Recommendations were developed to improve the efficiency of ultrasound conducted in the third trimester (T3), because neonatal consequences can be significant. This study aims to evaluate screening of SGA during T3 ultrasound and to describe causes for failure and differences with the recommendations of CNGOF. All children born between 2011 and 2012 with a birth weight below the 3rd percentile were included in this observational, retrospective, monocentric study. We noted that the diagnosis of SGA was placed on file. Then, as recommended by the CNGOF, we calculated estimated fetal weight (EFW) with Hadlock 3 and Hadlock 4, and the corresponding percentiles, using the biometrics from the ultrasound report. We thus could evaluate a new screening rate with SGA fetus identified through this technique. A total of 142 patients were included. By calculating correctly all EFW and checking abdominal circumference percentiles, the screening rate of SGA fetuses with T3 ultrasound increased from 40 % to 50 % and the overall screening rate (clinical and ultrasound) from 54 % to 66 %. By following the recommendations we found a real improvement in fetal SGA screening rates to T3 ultrasound with a potential benefit for their care. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  5. A random variance model for detection of differential gene expression in small microarray experiments.

    Science.gov (United States)

    Wright, George W; Simon, Richard M

    2003-12-12

    Microarray techniques provide a valuable way of characterizing the molecular nature of disease. Unfortunately expense and limited specimen availability often lead to studies with small sample sizes. This makes accurate estimation of variability difficult, since variance estimates made on a gene by gene basis will have few degrees of freedom, and the assumption that all genes share equal variance is unlikely to be true. We propose a model by which the within gene variances are drawn from an inverse gamma distribution, whose parameters are estimated across all genes. This results in a test statistic that is a minor variation of those used in standard linear models. We demonstrate that the model assumptions are valid on experimental data, and that the model has more power than standard tests to pick up large changes in expression, while not increasing the rate of false positives. This method is incorporated into BRB-ArrayTools version 3.0 (http://linus.nci.nih.gov/BRB-ArrayTools.html). ftp://linus.nci.nih.gov/pub/techreport/RVM_supplement.pdf

  6. Small Microbial Three-Electrode Cell Based Biosensor for Online Detection of Acute Water Toxicity.

    Science.gov (United States)

    Yu, Dengbin; Zhai, Junfeng; Liu, Changyu; Zhang, Xueping; Bai, Lu; Wang, Yizhe; Dong, Shaojun

    2017-11-22

    The monitoring of toxicity of water is very important to estimate the safety of drinking water and the level of water pollution. Herein, a small microbial three-electrode cell (M3C) biosensor filled with polystyrene particles was proposed for online monitoring of the acute water toxicity. The peak current of the biosensor related with the performance of the bioanode was regarded as the toxicity indicator, and thus the acute water toxicity could be determined in terms of inhibition ratio by comparing the peak current obtained with water sample to that obtained with nontoxic standard water. The incorporation of polystyrene particles in the electrochemical cell not only reduced the volume of the samples used, but also improved the sensitivity of the biosensor. Experimental conditions including washing time with PBS and the concentration of sodium acetate solution were optimized. The stability of the M3C biosensor under optimal conditions was also investigated. The M3C biosensor was further examined by formaldehyde at the concentration of 0.01%, 0.03%, and 0.05% (v/v), and the corresponding inhibition ratios were 14.6%, 21.6%, and 36.4%, respectively. This work provides a new insight into the development of an online toxicity detector based on M3C biosensor.

  7. Size Exclusion HPLC Detection of Small-Size Impurities as a Complementary Means for Quality Analysis of Extracellular Vesicles

    Directory of Open Access Journals (Sweden)

    Tao Huang

    2015-07-01

    Full Text Available For extracellular vesicle research, whether for biomarker discoveries or therapeutic applications, it is critical to have high-quality samples. Both microscopy and NanoSight Tracking Analysis (NTA for size distribution have been used to detect large vesicles. However, there is currently no well-established method that is convenient for routine quality analysis of small-size impurities in vesicle samples. In this paper we report a convenient method, called ‘size-exclusion high-performance liquid chromatography’ (SE-HPLC, alongside NTA and Microscopy analysis to guide and qualify the isolation and processing of vesicles. First, the SE-HPLC analysis was used to detect impurities of small-size proteins during the ultra-centrifugation process of vesicle isolation; it was then employed to test the changes of vesicles under different pH conditions or integrity after storage. As SE-HPLC is generally accessible in most institutions, it could be used as a routine means to assist researchers in examining the integrity and quality of extracellular vesicles along with other techniques either during isolation/preparation or for further engineering and storage.

  8. Comparison of gadolinium-EOB-DTPA-enhanced and diffusion-weighted liver MRI for detection of small hepatic metastases.

    Science.gov (United States)

    Shimada, Kotaro; Isoda, Hiroyoshi; Hirokawa, Yuusuke; Arizono, Shigeki; Shibata, Toshiya; Togashi, Kaori

    2010-11-01

    To compare the accuracy of gadolinium ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI with that of diffusion-weighted MRI (DWI) in the detection of small hepatic metastases (2 cm or smaller). Forty-five patients underwent abdominal MRI at 3 T, including T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), heavily T2WI (HASTE), DWI with a b-value of 500 s/mm(2) and contrast-enhanced MRI with Gd-EOB-DTPA. Two groups were assigned and compared: group A (T1WI, T2WI, HASTE and contrast-enhanced study with Gd-EOB-DTPA), and group B (T1WI, T2WI, HASTE and DWI). Two observers independently interpreted the images obtained in a random order. For all hepatic metastases, the diagnostic performance using each imaging set was evaluated by receiver-operating characteristic (ROC) curve analysis. A total of 51 hepatic metastases were confirmed. The area under the ROC curve (Az) of group A was larger than that of group B, and the difference in the mean Az values between the two image sets was statistically significant, whereas, there were three metastases that lay near thin vessels or among multiple cysts and were better visualised in group B than in group A. Gd-EOB-DTPA-enhanced MRI showed higher accuracy in the detection of small metastases than DWI.

  9. Craft vs. industrial: Habits, attitudes and motivations towards beer consumption in Mexico.

    Science.gov (United States)

    Gómez-Corona, Carlos; Escalona-Buendía, Héctor B; García, Mauricio; Chollet, Sylvie; Valentin, Dominique

    2016-01-01

    Food choices tend to be stable over time; they do not change fast, since consumers tend to act like creatures of habits. However, food habits can evolve, like currently the craft beer category. A change of habits involves a change of perception towards a product. Therefore, what is changing in the perception of beer? Two studies were conducted to address this question. First study was preliminary and aimed at exploring beer consumption habits in Mexico and a better understanding of craft beer representation among beer users. A questionnaire was administrated to 207 consumers in Mexico City during a beer festival. Results showed that respondents could be classified in: industrial beer (41.1%), occasional industrial (24.1%), and craft beer (34.8%) consumers. Craft cluster included mostly 25-35 years old men with high-income level. Among the craft beers cited by respondents from this cluster some are industrial, suggesting that the concept of craft beer might not be well defined, or defined in ideological terms. The second and main study was conducted using consumer ethnographies to understand the motivations and benefits of craft beer consumption. Opposite to industrial, craft beer emerges as an experience-based and symbolic product rather than a utilitarian one. The main motivation for drinking craft beer seems to be the quest of authenticity. Respondents' motivations to drink craft beer are generated by three important factors: desire for more knowledge, new taste experiences, and move away from the mainstream beer consumption. Craft consumers do not drink the product for its functional attributes, they consume it for what it means and as a consequence they build an identity, perceived as more authentic and unique, in comparison to the mainstream industrial beer consumption in Mexico. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Simulating high frequency water quality monitoring data using a catchment runoff attenuation flux tool (CRAFT).

    Science.gov (United States)

    Adams, Russell; Quinn, Paul F; Perks, Matthew; Barber, Nicholas J; Jonczyk, Jennine; Owen, Gareth J

    2016-12-01

    High resolution water quality data has recently become widely available from numerous catchment based monitoring schemes. However, the models that can reproduce time series of concentrations or fluxes have not kept pace with the advances in monitoring data. Model performance at predicting phosphorus (P) and sediment concentrations has frequently been poor with models not fit for purpose except for predicting annual losses. Here, the data from the Eden Demonstration Test Catchments (DTC) project have been used to calibrate the Catchment Runoff Attenuation Flux Tool (CRAFT), a new, parsimonious model developed with the aim of modelling both the generation and attenuation of nutrients and sediments in small to medium sized catchments. The CRAFT has the ability to run on an hourly timestep and can calculate the mass of sediments and nutrients transported by three flow pathways representing rapid surface runoff, fast subsurface drainage and slow groundwater flow (baseflow). The attenuation feature of the model is introduced here; this enables surface runoff and contaminants transported via this pathway to be delayed in reaching the catchment outlet. It was used to investigate some hypotheses of nutrient and sediment transport in the Newby Beck Catchment (NBC) Model performance was assessed using a suite of metrics including visual best fit and the Nash-Sutcliffe efficiency. It was found that this approach for water quality models may be the best assessment method as opposed to using a single metric. Furthermore, it was found that, when the aim of the simulations was to reproduce the time series of total P (TP) or total reactive P (TRP) to get the best visual fit, that attenuation was required. The model will be used in the future to explore the impacts on water quality of different mitigation options in the catchment; these will include attenuation of surface runoff. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Developing works to detect fatigue cracks (small sodium leak detector and acoustic emission

    International Nuclear Information System (INIS)

    Kikuchi, M.; Sakakibara, Y.; Nagata, T.

    1980-01-01

    Continuous monitoring of fatigue cracks was performed (using both sodium leak detector and AE measuring system) through the creep-fatigue test of 304 stainless steel long elbow as part of the test series to establish the structural reliability of the Prototype FBR primary heat transport piping system. The sodium leak detector was a system composed mainly of SID (Sodium Ionization Detector) and DPD (Deferential Pressure Detector), that was developed by HITACHI Ltd. under a contract with PNC. The AE system was Synthetic AE Measuring and Analyzing system that was developed at FBR Safety Section to measure and analyze AE at various piping component tests. The test was continued until a sodium leakage was detected by the contact-type sodium leak detector attached to the test assembly, after about 4 weeks operation under cyclic loading at 600 deg. C. The following conclusions were obtained: (1) The sodium leak detector, both SID and DPD, indicated sodium leakage clearly, some hours before the contact-type detector did, even under an environment of air that contains ordinary humidity (Leaked sodium was estimated to be less than 15 grams after completion of the test); (2) The AE method indicated location and seriousness of the fatigue cracks, apparently before the crack penetration occurred. (author)

  12. Detection of seizures from small samples using nonlinear dynamic system theory.

    Science.gov (United States)

    Yaylali, I; Koçak, H; Jayakar, P

    1996-07-01

    The electroencephalogram (EEG), like many other biological phenomena, is quite likely governed by nonlinear dynamics. Certain characteristics of the underlying dynamics have recently been quantified by computing the correlation dimensions (D2) of EEG time series data. In this paper, D2 of the unbiased autocovariance function of the scalp EEG data was used to detect electrographic seizure activity. Digital EEG data were acquired at a sampling rate of 200 Hz per channel and organized in continuous frames (duration 2.56 s, 512 data points). To increase the reliability of D2 computations with short duration data, raw EEG data were initially simplified using unbiased autocovariance analysis to highlight the periodic activity that is present during seizures. The D2 computation was then performed from the unbiased autocovariance function of each channel using the Grassberger-Procaccia method with Theiler's box-assisted correlation algorithm. Even with short duration data, this preprocessing proved to be computationally robust and displayed no significant sensitivity to implementation details such as the choices of embedding dimension and box size. The system successfully identified various types of seizures in clinical studies.

  13. Detection of wood cell wall porosity using small carbohydrate molecules and confocal fluorescence microscopy.

    Science.gov (United States)

    Donaldson, L A; Kroese, H W; Hill, S J; Franich, R A

    2015-09-01

    A novel approach to nanoscale detection of cell wall porosity using confocal fluorescence microscopy is described. Infiltration of cell walls with a range of nitrophenyl-substituted carbohydrates of different molecular weights was assessed by measuring changes in the intensity of lignin fluorescence, in response to the quenching effect of the 4-nitrophenyl group. The following carbohydrates were used in order of increasing molecular weight; 4-nitrophenyl β-D-glucopyrano-side (monosaccharide), 4-nitrophenyl β-D-lactopyranoside (disaccharide), 2-chloro-4-nitrophenyl β-D-maltotrioside (trisaccharide), and 4-nitrophenyl α-D-maltopentaoside (pentasaccharide). This technique was used to compare cell wall porosity in wood which had been dewatered to 40% moisture content using supercritical CO2, where cell walls remain fully hydrated, with kiln dried wood equilibrated to 12% moisture content. Infiltration of cell walls as measured by fluorescence quenching, was found to decrease with increasing molecular weight, with the pentasaccharide being significantly excluded compared to the monosaccharide. Porosity experiments were performed on blocks and sections to assess differences in cell wall accessibility. Dewatered and kiln dried wood infiltrated as blocks showed similar results, but greater infiltration was achieved by using sections, indicating that not all pores were easily accessible by infiltration from the lumen surface. In wood blocks infiltrated with 4-nitrophenyl α-D-maltopentaoside, quenching of the secondary wall was quite variable, especially in kiln dried wood, indicating limited connectivity of pores accessible from the lumen surface. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.

  14. Quantitative investigation of a novel small field of view hybrid gamma camera (HGC) capability for sentinel lymph node detection

    Science.gov (United States)

    Lees, John E; Bugby, Sarah L; Jambi, Layal K; Perkins, Alan C

    2016-01-01

    Objective: The hybrid gamma camera (HGC) has been developed to enhance the localization of radiopharmaceutical uptake in targeted tissues during surgical procedures such as sentinel lymph node (SLN) biopsy. To assess the capability of the HGC, a lymph node contrast (LNC) phantom was constructed to simulate medical scenarios of varying radioactivity concentrations and SLN size. Methods: The phantom was constructed using two clear acrylic glass plates. The SLNs were simulated by circular wells of diameters ranging from 10 to 2.5 mm (16 wells in total) in 1 plate. The second plate contains four larger rectangular wells to simulate tissue background activity surrounding the SLNs. The activity used to simulate each SLN ranged between 4 and 0.025 MBq. The activity concentration ratio between the background and the activity injected in the SLNs was 1 : 10. The LNC phantom was placed at different depths of scattering material ranging between 5 and 40 mm. The collimator-to-source distance was 120 mm. Image acquisition times ranged from 60 to 240 s. Results: Contrast-to-noise ratio analysis and full-width-at-half-maximum (FWHM) measurements of the simulated SLNs were carried out for the images obtained. Over the range of activities used, the HGC detected between 87.5 and 100% of the SLNs through 20 mm of scattering material and 75–93.75% of the SLNs through 40 mm of scattering material. The FWHM of the detected SLNs ranged between 11.93 and 14.70 mm. Conclusion: The HGC is capable of detecting low accumulation of activity in small SLNs, indicating its usefulness as an intraoperative imaging system during surgical SLN procedures. Advances in knowledge: This study investigates the capability of a novel small-field-of-view (SFOV) HGC to detect low activity uptake in small SLNs. The phantom and procedure described are inexpensive and could be easily replicated and applied to any SFOV camera, to provide a comparison between systems with clinically relevant

  15. Experimental high-frequency ultrasound can detect graft rejection after small bowel transplantation.

    Science.gov (United States)

    Yang, R; Liu, Q; Wu, E X; Pescovitz, M D; Collins, M H; Kopecky, K K; Grosfeld, J L

    1994-02-01

    Early diagnosis of graft rejection after small bowel transplantation (SBT) can allow prompt institution of vigorous immunosuppressive therapy, with resultant reversal of the rejection process. The current method for graft monitoring is random mucosal biopsy from a stomal site or through an endoscope. However, because early rejection often has a patchy distribution, it could be missed by random biopsy. We hypothesized that the pathological process of rejection would alter acoustic impedance of the tissue and thus change the ultrasonic patterns of the graft intestinal wall. If this hypothesis is correct, then high-frequency endoscopic ultrasound (US) could be used to monitor the entire transplanted bowel and guide the biopsy, with improved yields. This hypothesis was tested in a rat orthotopic SBT model. Sixty-two intestinal specimens (9 isografts, 12 allografts treated with cyclosporine A [CsA], 22 untreated allografts, and 19 intestines from normal rats) were collected for in vitro transluminal US imaging (30 MHz) and histopathologic study. The echo pattern of normal rat intestinal wall consisted of five echo layers that correlated spatially with the histological layers: the innermost hyperechoic layer 1, plus hypoechoic layer 2, corresponded to the mucosa; hyperechoic layer 3, the submucosa; anechoic layer 4, the muscularis propria; and hyperechoic layer 5, the serosa. The isografts and CsA-treated allografts were identical histologically and ultrasonically to normal intestine. However, the echo patterns of the untreated allografts had progressive loss of architectural stratification, with worsening rejection. The change began with patchy indistinctness and disruption of hyperechoic layers 1, 3 and 5, and progressed to total obliteration of the layers, with the intestinal wall becoming a nonstratified hypoechoic structure.(ABSTRACT TRUNCATED AT 250 WORDS)

  16. A study on the performance evaluation of small gamma camera collimators using detective quantun efficiency

    International Nuclear Information System (INIS)

    Jeon, Ho Sang

    2008-02-01

    The anger-type gamma camera and novel marker compound using Tc-99m were firstly introduced in 1963. The gamma camera systems have being improved and applied to various fields, for example, medical, industrial, and environmental fields. Gamma camera is mainly composed of collimator, detector, and signal processor. And the radiative source is namely the imaging object. The collimator is essential component of gamma camera system because the imaging performance of system is mainly dependent on the collimator. The performance evaluation of collimators can be done by using evaluating factors. In this study, the novel factors for gamma camera evaluation are suggested. The established evaluating factors by NEMA are FWHM, sensitivity, and uniformity. They have some limitations in spite of their usefulness. Firstly, performance evaluation by those factors give insensitive and indirect results only. Secondly, the evaluation of noise property is ambiguous. Thirdly, there is no synthetic evaluation of system performance. Simulation with Monte Carlo code and experiment with a small camera camera were simultaenuously performed to verify novel evaluating factors. For the evaluation of spatial resolution, MTF was applied instead of FWHM. The MTF values presents excellent linear relationship with FWHM values. The NNPS was applied instead of uniformity and sensitivity for the evaluation of noise fluctuation. The NNPS values also presents linear relationship with sensitivity and unifomity. Moreover, these novel factors give quantities as the function of spatial frequencies. Finally, the DQE values were given by calculations with MTF, NNPS, and input SNR. DQE effectively presents the synthetic evaluation of gamma camera performance. It is the conclusion that MTF, NNPS, and DQE can be novel evaluating factors for gamma camera systems and the new factor for synthetic evaluation is derived

  17. A universal aptameric biosensor: Multiplexed detection of small analytes via aggregated perylene-based broad-spectrum quencher.

    Science.gov (United States)

    Hu, Rong; Zhang, Xi; Xu, Qiang; Lu, Dan-Qing; Yang, Yun-Hui; Xu, Quan-Qing; Ruan, Qiong; Mo, Liu-Ting; Zhang, Xiao-Bing

    2017-06-15

    A universal aptameric system based on the taking advantage of double-stranded DNA/perylene diimide (dsDNA/PDI) as the signal probe was developed for multiplexed detection of small molecules. Aptamers are single-stranded DNA or RNA oligonucleotides which are selected in vitro by a process known as systematic evolution of ligands by exponential enrichment. In this work, we synthesized a new kind of PDI and reported this aggregated PDI could quench the double-stranded DNA (dsDNA)-labeled fluorophores with a high quenching efficiency. The quenching efficiencies on the fluorescence of FAM, TAMRA and Cy5 could reach to 98.3%±0.9%, 97.2%±0.6% and 98.1%±1.1%, respectively. This broad-spectrum quencher was then adopted to construct a multicolor biosensor via a label-free approach. A structure-switching-triggered enzymatic recycling amplification was employed for signal amplification. High quenching efficiency combined with autocatalytic target recycling amplification afforded the biosensor with high sensitivity towards small analytes. For other targets, changing the corresponding aptamer can achieve the goal. The quencher did not interfere with the catalytic activity of nuclease. The biosensor could be manipulated with similar sensitivity no matter in pre-addition or post-addition manner. Moreover, simultaneous and multiplexed analysis of several small molecules in homogeneous solution was achieved, demonstrating its potential application in the rapid screening of multiple biotargets. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Mammographic casting-type calcification associated with small screen-detected invasive breast cancers: is this a reliable prognostic indicator?

    International Nuclear Information System (INIS)

    Peacock, C.; Given-Wilson, R.M.; Duffy, S.W.

    2004-01-01

    AIM: The aim of the present study was to establish whether mammographic casting-type calcification associated with small screen-detected invasive breast cancers is a reliable prognostic indicator. METHODS AND MATERIALS: We retrospectively identified 50 consecutive women diagnosed with an invasive cancer less than 15 mm who showed associated casting calcification on their screening mammograms. Controls were identified that showed no microcalcification and were matched for tumour size, histological type and lymph node status. A minimum of 5 years follow-up was obtained, noting recurrence and outcome. Conditional and unconditional logistic regression, depending on the outcome variable, were used to analyse the data, taking the matched design into account in both cases. Where small numbers prohibited the use of logistic regression, Fisher's exact test was used. RESULTS: Five deaths from breast cancer occurred out of the 50 cases, of which three were lymph node positive, two were lymph node negative and none were grade 3. None of the 78 control cases died from breast cancer. The difference in breast cancer death rates was significant by Fisher's exact test (p=0.02). Risk of recurrence was also significantly increased in the casting cases (OR=3.55, 95% CI 1.02-12.33, p=0.046). CONCLUSION: Although the overall outcome for small screen-detected breast cancers is good, our study suggests that casting calcification is a poorer prognostic factor. The advantage of a mammographic feature as an independent prognostic indicator lies in early identification of high-risk patients, allowing optimization of management

  19. Capillary gel electrophoresis-coupled aptamer enzymatic cleavage protection strategy for the simultaneous detection of multiple small analytes.

    Science.gov (United States)

    Perrier, Sandrine; Zhu, Zhenyu; Fiore, Emmanuelle; Ravelet, Corinne; Guieu, Valérie; Peyrin, Eric

    2014-05-06

    This novel, multi small-analyte sensing strategy is the result of combining the target-induced aptamer enzymatic protection approach with the CGE-LIF (capillary gel electrophoresis with laser-induced fluorescence) technique. The implemented assay principle is based on an analysis of the phosphodiesterase I (PDE I)-mediated size variation of a fluorescein-labeled aptamer (FApt), the enzyme catalyzing the removal of nucleotides from DNA in the 3' to 5' direction. In the absence of the target, the unfolded aptamer was enzymatically cleaved into short DNA fragments. Upon target binding, the DNA substrate was partially protected against enzymatic hydrolysis. The amount of bound aptamer remaining after the exonuclease reaction was proportional to the concentration of the target. The CGE technique, which was used to determine the separation of FApt species from DNA digested products, permitted the quantification of adenosine (A), ochratoxin A (O), and tyrosinamide (T) under the same optimized enzymatic conditions. This assay strategy was subsequently applied to the simultaneous detection of A, O, and T in a single capillary under buffered conditions using corresponding FApt probes of different lengths (23, 36, and 49 nucleotides, respectively). Additionally, the detection of these three small molecules was successfully achieved in a complex medium (diluted, heat-treated human serum) showing a good recovery. It is worth noting that the multiplexed analysis was accomplished for targets with different charge states by using aptamers possessing various structural features. This sensing platform constitutes a rationalized and reliable approach with an expanded potential for a high-throughput determination of small analytes in a single capillary.

  20. [Serological detection of Brucella suis, influenza virus and Aujeszky's disease virus in backyard and small swine holders in Argentina].

    Science.gov (United States)

    Dibarbora, Marina; Cappuccio, Javier A; Aznar, María N; Bessone, Fernando A; Piscitelli, Hernán; Pereda, Ariel J; Pérez, Daniel R

    Farmers raising less than 100 sows represent more than 99% of swine producers in Argentina, although little is known about their sanitary status and productive characteristics in the country. Sanitary and productive information was obtained. Furthermore, samples for serological studies were taken to detect antibodies against Brucella suis (Bs), Aujeszky's disease virus (AV) and influenza virus (IV) in 68 backyard and small producers with less than 100 sows located in the north, central and south regions of Argentina. Antibodies against H1 pandemic were detected in 80% of the farms while 11%, 11.7% and 6.0% of the producers were positive to influenza H3 cluster 2, AV and Bs, respectively. None of the producers was aware of the risk factors concerning the transmission of diseases from pigs to humans. A percentage of 47% of them buy pigs for breeding from other farmers and markets. With regard to biosecurity measures, only 16% of the farms had perimeter fences. The results of this study demonstrate that productive characterization and disease surveys are important to improve productivity and to reduce the risk of disease transmission among animals and humans. The study of sanitary status and risk factors is necessary for better control and eradication of diseases in backyard or small producers. More representative studies at country level should be carried out to detect the pathogensthat circulate and, with this knowledge, to implement prevention and control measures. Copyright © 2017 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  1. Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors.

    Science.gov (United States)

    Cui, Tao; Hurtig, Monica; Elgue, Graciela; Li, Su-Chen; Veronesi, Giulia; Essaghir, Ahmed; Demoulin, Jean-Baptiste; Pelosi, Giuseppe; Alimohammadi, Mohammad; Öberg, Kjell; Giandomenico, Valeria

    2010-12-30

    Small intestine neuroendocrine tumors (SI-NETs) belong to a rare group of cancers. Most patients have developed metastatic disease at the time of diagnosis, for which there is currently no cure. The delay in diagnosis is a major issue in the clinical management of the patients and new markers are urgently needed. We have previously identified paraneoplastic antigen Ma2 (PNMA2) as a novel SI-NET tissue biomarker. Therefore, we evaluated whether Ma2 autoantibodies detection in the blood stream is useful for the clinical diagnosis and recurrence of SI-NETs. A novel indirect ELISA was set up to detect Ma2 autoantibodies in blood samples of patients with SI-NET at different stages of disease. The analysis was extended to include typical and atypical lung carcinoids (TLC and ALC), to evaluate whether Ma2 autoantibodies in the blood stream become a general biomarker for NETs. In total, 124 blood samples of SI-NET patients at different stages of disease were included in the study. The novel Ma2 autoantibody ELISA showed high sensitivity, specificity and accuracy with ROC curve analysis underlying an area between 0.734 and 0.816. Ma2 autoantibodies in the blood from SI-NET patients were verified by western blot and sequential immunoprecipitation. Serum antibodies of patients stain Ma2 in the tumor tissue and neurons. We observed that SI-NET patients expressing Ma2 autoantibody levels below the cutoff had a longer progression and recurrence-free survival compared to those with higher titer. We also detected higher levels of Ma2 autoantibodies in blood samples from TLC and ALC patients than from healthy controls, as previously shown in small cell lung carcinoma samples. Here we show that high Ma2 autoantibody titer in the blood of SI-NET patients is a sensitive and specific biomarker, superior to chromogranin A (CgA) for the risk of recurrence after radical operation of these tumors.

  2. Very small embryonic-like stem cells (VSELs) detected in azoospermic testicular biopsies of adult survivors of childhood cancer.

    Science.gov (United States)

    Kurkure, Purna; Prasad, Maya; Dhamankar, Vandana; Bakshi, Ganesh

    2015-11-09

    Infertility is a known side-effect of oncotherapy in cancer survivors, and often compromises the quality of life. The present study was undertaken to detect very small embryonic-like stem cells (VSELs) in testicular biopsies from young adult survivors of childhood cancer who had azoospermia. VSELs have been earlier reported in human and mouse testes. They resist busulphan treatment in mice and potentially restore spermatogenesis when the somatic niche is restored by transplanting Sertoli or mesenchymal cells. VSELs also have the potential to differentiate into sperm in vitro. The study had clearance from Institutional review board (IRB). Seven azoospermic survivors of childhood cancer were included in the study after obtaining their informed consent. Semen analysis was done to confirm azoospermia prior to inclusion in the study. Testicular biopsies were performed at the Uro-oncology Unit of the hospital and then used for various studies to detect VSELs. Hematoxylin and Eosin stained tubular sections confirmed azoospermia and smears revealed the presence of very small, spherical VSELs with high nucleo-cytoplasmic ratio, in addition to the Sertoli cells. Immuno-localization studies on testicular smears showed that the VSELs were CD133+/CD45-/LIN-, expressed nuclear OCT-4, STELLA and cell surface SSEA-4. Pluripotent transcripts Oct-4A, Nanog and Sox-2 were detected in azoospermic samples whereas marked reduction was observed in germ cell markers Oct-4 and Boule. The present study demonstrates the presence of pluripotent VSELs in the testicular biopsy of azoospermic adult survivors of childhood cancer. It is likely that these persisting VSELs can restore spermatogenesis as demonstrated in mice studies. Therefore, pilot studies need to be undertaken using autologous mesenchymal cells with a hope to restore testicular function and fertility in cancer survivors. The results of this study assume a great significance in the current era, where cryopreservation of testicular

  3. Immunophenotype of leukemic blasts with small peroxidase-positive granules detected by electron microscopy.

    Science.gov (United States)

    Vainchenker, W; Villeval, J L; Tabilio, A; Matamis, H; Karianakis, G; Guichard, J; Henri, A; Vernant, J P; Rochant, H; Breton-Gorius, J

    1988-05-01

    Forty-three cases of undifferentiated leukemias by light microscopy examination were diagnosed as acute myeloblastic leukemias by ultrastructural revelation of peroxidase and were subsequently studied by immunological markers. In 41 of these cases, blasts were labeled by at least one of the antimyeloid MoAbs (My 7, My 9, and 80H5). An antimyeloperoxidase polyclonal antibody was used in 23 cases and was clearly positive in 11 of them, while cytochemistry by light microscopy was negative. These myeloblasts were frequently mixed with a minority of blasts from other lineages especially promegakaryoblasts. It is noteworthy that in 6 cases myeloid and lymphoid markers (E rosette receptor, common acute lymphoblastic leukemia antigen (cALLA), CD 9, CD 19 antigens (anti-B4 MoAb] were detected on a fraction of blast cells, suggesting a bilineage leukemia. However, in double labeling experiments, blasts with myeloperoxidase coexpressed lymphoid and myeloid markers including cALLA and CD 19 antigen. In one case, blasts had a typical non-B, non-T acute lymphoblastic leukemia phenotype (HLA-DR, CD 9, CD 19, cALLA positive) without staining by any of the antimyeloid MoAbs. However, 70% of the blasts were labeled by the antimyeloperoxidase antibody and expressed peroxidase-positive granules at ultrastructural level. In conclusion, most of the AML undiagnosed by optical cytochemistry are identified by antimyeloid antibodies. Some of these cases are also stained by some antilymphoid MoAbs. Use of antibodies against myeloperoxidase may improve the diagnosis of difficult cases of acute myeloblastic leukemia.

  4. DETECTION OF SMALL-SCALE GRANULAR STRUCTURES IN THE QUIET SUN WITH THE NEW SOLAR TELESCOPE

    International Nuclear Information System (INIS)

    Abramenko, V. I.; Yurchyshyn, V. B.; Goode, P. R.; Kitiashvili, I. N.; Kosovichev, A. G.

    2012-01-01

    Results of a statistical analysis of solar granulation are presented. A data set of 36 images of a quiet-Sun area on the solar disk center was used. The data were obtained with the 1.6 m clear aperture New Solar Telescope at Big Bear Solar Observatory and with a broadband filter centered at the TiO (705.7 nm) spectral line. The very high spatial resolution of the data (diffraction limit of 77 km and pixel scale of 0.''0375) augmented by the very high image contrast (15.5% ± 0.6%) allowed us to detect for the first time a distinct subpopulation of mini-granular structures. These structures are dominant on spatial scales below 600 km. Their size is distributed as a power law with an index of –1.8 (which is close to the Kolmogorov's –5/3 law) and no predominant scale. The regular granules display a Gaussian (normal) size distribution with a mean diameter of 1050 km. Mini-granular structures contribute significantly to the total granular area. They are predominantly confined to the wide dark lanes between regular granules and often form chains and clusters, but different from magnetic bright points. A multi-fractality test reveals that the structures smaller than 600 km represent a multi-fractal, whereas on larger scales the granulation pattern shows no multi-fractality and can be considered as a Gaussian random field. The origin, properties, and role of the population of mini-granular structures in the solar magnetoconvection are yet to be explored.

  5. Feasibility of OCT to detect radiation-induced esophageal damage in small animal models (Conference Presentation)

    Science.gov (United States)

    Jelvehgaran, Pouya; Alderliesten, Tanja; Salguero, Javier; Borst, Gerben; Song, Ji-Ying; van Leeuwen, Ton G.; de Boer, Johannes F.; de Bruin, Daniel M.; van Herk, Marcel B.

    2016-03-01

    Lung cancer survival is poor and radiotherapy patients often suffer serious treatment side effects. The esophagus is particularly sensitive leading to reduced food intake or even fistula formation. Only few direct techniques exist to measure radiation-induced esophageal damage, for which knowledge is needed to improve the balance between risk of tumor recurrence and complications. Optical coherence tomography (OCT) is a minimally-invasive imaging technique that obtains cross-sectional, high-resolution (1-10µm) images and is capable of scanning the esophageal wall up to 2-3mm depth. In this study we investigated the feasibility of OCT to detect esophageal radiation damage in mice. In total 30 mice were included in 4 study groups (1 main and 3 control groups). Mice underwent cone-beam CT imaging for initial setup assessment and dose planning followed by single-fraction dose delivery of 4, 10, 16, and 20Gy on 5mm spots, spaced 10mm apart. Mice were repeatedly imaged using OCT: pre-irradiation and up to 3 months post-irradiation. The control groups received either OCT only, irradiation only, or were sham-operated. We used histopathology as gold standard for radiation-induced damage diagnosis. The study showed edema in both the main and OCT-only groups. Furthermore, radiation-induced damage was primarily found in the highest dose region (distal esophagus). Based on the histopathology reports we were able to identify the radiation-induced damage in the OCT images as a change in tissue scattering related to the type of induced damage. This finding indicates the feasibility and thereby the potentially promising role of OCT in radiation-induced esophageal damage assessment.

  6. FEASIBILITY STUDY OF INEXPENSIVE THERMAL SENSORS AND SMALL UAS DEPLOYMENT FOR LIVING HUMAN DETECTION IN RESCUE MISSIONS APPLICATION SCENARIOS

    Directory of Open Access Journals (Sweden)

    E. Levin

    2016-06-01

    Full Text Available Significant efforts are invested by rescue agencies worldwide to save human lives during natural and man-made emergency situations including those that happen in wilderness locations. These emergency situations include but not limited to: accidents with alpinists, mountainous skiers, people hiking and lost in remote areas. Sometimes in a rescue operation hundreds of first responders are involved to save a single human life. There are two critical issues where geospatial imaging can be a very useful asset in rescue operations support: 1 human detection and 2 confirming a fact that detected a human being is alive. International group of researchers from the Unites States and Poland collaborated on a pilot research project devoted to identify a feasibility of use for the human detection and alive-human state confirmation small unmanned aerial vehicles (SUAVs and inexpensive forward looking infrared (FLIR sensors. Equipment price for both research teams was below $8,000 including 3DR quadrotor UAV and Lepton longwave infrared (LWIR imager which costs around $250 (for the US team; DJI Inspire 1 UAS with commercial Tamarisc-320 thermal camera (for the Polish team. Specifically both collaborating groups performed independent experiments in the USA and Poland and shared imaging data of on the ground and airborne electro-optical and FLIR sensor imaging collected. In these experiments dead bodies were emulated by use of medical training dummies. Real humans were placed nearby as live human subjects. Electro-optical imagery was used for the research in optimal human detection algorithms. Furthermore, given the fact that a dead human body after several hours has a temperature of the surrounding environment our experiments were challenged by the SUAS data optimization, i.e., distance from SUAV to object so that the FLIR sensor is still capable to distinguish temperature differences between a dummy and a real human. Our experiments indicated feasibility of

  7. Direct Determination of a Small-Molecule Drug, Valproic Acid, by an Electrically-Detected Microcantilever Biosensor for Personalized Diagnostics

    Directory of Open Access Journals (Sweden)

    Long-Sun Huang

    2015-01-01

    Full Text Available Direct, small-molecule determination of the antiepileptic drug, valproic acid, was investigated by a label-free, nanomechanical biosensor. Valproic acid has long been used as an antiepileptic medication, which is administered through therapeutic drug monitoring and has a narrow therapeutic dosage range of 50–100 μg·mL−1 in blood or serum. Unlike labeled and clinically-used measurement techniques, the label-free, electrical detection microcantilever biosensor can be miniaturized and simplified for use in portable or hand-held point-of-care platforms or personal diagnostic tools. A micromachined microcantilever sensor was packaged into the micro-channel of a fluidic system. The measurement of the antiepileptic drug, valproic acid, in phosphate-buffered saline and serum used a single free-standing, piezoresistive microcantilever biosensor in a thermally-controlled system. The measured surface stresses showed a profile over a concentration range of 50–500 μg·mL−1, which covered the clinically therapeutic range of 50–100 μg·mL−1. The estimated limit of detection (LOD was calculated to be 45 μg·mL−1, and the binding affinity between the drug and the antibody was measured at around 90 ± 21 μg·mL−1. Lastly, the results of the proposed device showed a similar profile in valproic acid drug detection with those of the clinically-used fluorescence polarization immunoassay.

  8. Using SPOT-5 HRG Data in Panchromatic Mode for Operational Detection of Small Ships in Tropical Area

    Directory of Open Access Journals (Sweden)

    Michel Petit

    2008-05-01

    Full Text Available Nowadays, there is a growing interest in applications of space remote sensing systems for maritime surveillance which includes among others traffic surveillance, maritime security, illegal fisheries survey, oil discharge and sea pollution monitoring. Within the framework of several French and European projects, an algorithm for automatic ship detection from SPOT-5 HRG data was developed to complement existing fishery control measures, in particular the Vessel Monitoring System. The algorithm focused on feature-based analysis of satellite imagery. Genetic algorithms and Neural Networks were used to deal with the feature-borne information. Based on the described approach, a first prototype was designed to classify small targets such as shrimp boats and tested on panchromatic SPOT-5, 5-m resolution product taking into account the environmental and fishing context. The ability to detect shrimp boats with satisfactory detection rates is an indicator of the robustness of the algorithm. Still, the benchmark revealed problems related to increased false alarm rates on particular types of images with a high percentage of cloud cover and a sea cluttered background.

  9. Detecting Rice stripe virus (RSV) in the small brown planthopper (Laodelphax striatellus) with high specificity by RT-PCR.

    Science.gov (United States)

    Lijun, Cai; Xizhi, Ma; Lin, Kang; Kejing, Deng; Shouyuan, Zhao; Changben, Li

    2003-09-01

    Rice stripe disease, caused by Rice stripe virus (RSV), may lead to severe or even crippling losses in many rice-cultured countries and regions. As the most important vector of RSV, the small brown planthopper (SBPH) (Laodelphax striatellus) is largely responsible for the epidemic phase of the disease. Therefore, a rapid identification of RSV in the SBPH is of a great need for disease forecasting. A reverse transcription polymerase chain reaction (RT-PCR) assay is described to amplify a RSV gene in individual L. striatellus. By using primers matched to the viral RNA dependent RNA polymerase gene in RNA1, a 445 bp product was detected in viruliferous SBPHs. Meanwhile, the PCR products produced by the SBPH actin primers constructed across the boundary of an intron and an exon were used as RNA specific positive control for each stage of the experiment to ensure the validity of the negative results. Duplex RT-PCR conditions were established for the simultaneous detection of RSV and actin. This approach can be used for the early detection of RSV in L. striatellus and the subsequent rice stripe disease forecasting.

  10. JEAN CLAUDE RENARD: (POETRY AS CRAFT OF TRANSPARENCY

    Directory of Open Access Journals (Sweden)

    María del Sagrario Rollán

    2015-04-01

    Full Text Available The work of Jean-Claude Renard (Toulon 1922- Paris 2002 appears from the beginning marked by the metaphor of the journey - Songs for land lost (1947, and the craft of transparency. The poet begins the journey - that originates in the experience of death and destruction of a world shaken by the war, with a word that transcends the nonsense, and calls for “the country where forgiveness is / and are childhoods “a word that is built in search of human spaces and anticipates them. The adventure through the exercise of Solitude (1951, requirement beyond itself, a kind of internal and painful split: “I am separated from my heart,” releasing it, in turn, to the knowledge of the world and the gift that transfigures. The metamorphosis of the World (1951 takes place in the act of writing itself, for in him a knowledge of the essential reality is given, from which the party of pure celebrated say, “Oh breathing started / in the center of the loaf and snow “. Poetry as craft of transparency J.C. Renard develops in Un autre parole  (1981, prose poetry admirably clarifies its internal relations with theology and mysticism. The poet moves beyond “ailleurs” to a previous or future place of reconciliation and love letters between beings: “One happy pasture / leads above child / each wisdom to your name / and every love your body.”

  11. Inshore craft traditional working vessels of the british isles

    CERN Document Server

    Greenhill, Basil

    2013-01-01

    This comprehensive reference work describes and illustrates some 200 types of inshore craft that once fished and traded, under oar and sail, around the coasts of the British Isles. The types are arranged by coastal area and each is described in terms of its shape and design, fitness for location and purpose, build, evolution and geographical distribution. Details of dimensions, rig, building materials, seamanship and the survival of examples are given where known, while hundreds of line drawings and photographs show the vessels in their original forms.A team of twelve experts describe all these boat types and, in addition, there are introductions to the main geographic areas outlining the physical environments, fisheries and other uses of the sea that have influenced boat design; maps of all the areas show ports and physical features.At the beginning of the last century sail and oar dominated fisheries and local trade: one hundred years later those craft have all but vanished. This book brings alive for marit...

  12. Surveillance of FAP: a prospective blinded comparison of capsule endoscopy and other GI imaging to detect small bowel polyps

    Directory of Open Access Journals (Sweden)

    Tescher Paul

    2010-04-01

    Full Text Available Abstract Background Familial adenomatous polyposis (FAP is a hereditary disorder characterized by polyposis along the gastrointestinal tract. Information on adenoma status below the duodenum has previously been restricted due to its inaccessibility in vivo. Capsule Endoscopy (CE may provide a useful adjunct in screening for polyposis in the small bowel in FAP patients. This study aims to evaluate the effectiveness of CE in the assessment of patients with FAP, compared to other imaging modalities for the detection of small bowel polyps. Method 20 consecutive patients with previously diagnosed FAP and duodenal polyps, presenting for routine surveillance of polyps at The Royal Melbourne Hospital were recruited. Each fasted patient initially underwent a magnetic resonance image (MRI of the abdomen, and a barium small bowel follow-through study. Capsule Endoscopy was performed four weeks later on the fasted patient. An upper gastrointestinal side-viewing endoscopy was done one (1 to two (2 weeks after this. Endoscopists and investigators were blinded to results of other investigations and patient history. Results Within the stomach, upper gastrointestinal endoscopy found more polyps than other forms of imaging. SBFT and MRI generally performed poorly, identifying fewer polyps than both upper gastrointestinal and capsule endoscopy. CE was the only form of imaging that identified polyps in all segments of the small bowel as well as the only form of imaging able to provide multiple findings outside the stomach/duodenum. Conclusion CE provides important information on possible polyp development distal to the duodenum, which may lead to surgical intervention. The place of CE as an adjunct in surveillance of FAP for a specific subset needs consideration and confirmation in replication studies. Trial Registration Australian New Zealand Clinical Trials Registry ACTRN12608000616370

  13. Job crafting and its impact on work engagement and job satisfaction in mining and manufacturing

    NARCIS (Netherlands)

    De Beer, L.T. (Leon T.); M. Tims (Maria); A.B. Bakker (Arnold)

    2016-01-01

    textabstractThe purpose of this study was to investigate job crafting and its relationship with work engagement and job satisfaction within the South African context. This research is important as job crafting has been shown to have a positive influence on employee motivation. A cross-sectional

  14. Crafting qualities in designing QR-coded embroidery and bedtime stories

    NARCIS (Netherlands)

    Kuusk, K.; Wensveen, S.A.G.; Tomico, O.

    2014-01-01

    There is a renewed interest into crafts and what it can mean when integrating new technologies into textiles. This paper proposes to embed craft qualities and sustainable values into designing smart textile projects. Our design iterations QR-Coded Embroidery and Bedtime Stories combine textiles,

  15. The Need for the United States Army to Possess a Landing Craft with Maneuver Capabilities

    Science.gov (United States)

    2015-06-12

    landing craft after the 2004 Indian Ocean tsunami and the 2009 Myanmar cyclone.9 The landing craft enabled the relief effort to bypass partially...requirements for Army aviation . The Need for America’s Amphibious Capability In his thesis, “The Need for the United States of America’s Amphibious

  16. The job crafting intervention: effects on job resources, self-efficacy, and affective well-being

    NARCIS (Netherlands)

    van den Heuvel, M.; Demerouti, E.; Peeters, M.C.W.

    2015-01-01

    This quasi-experimental field study examines the effects of an intervention designed to boost job resources, affective well-being, and self-efficacy via job crafting behaviour. Employees (n = 39) in a Dutch police district received a 1-day training, after which they worked towards self-set crafting

  17. The job crafting intervention : Effects on job resources, self-efficacy, and affective well-being

    NARCIS (Netherlands)

    van den Heuvel, Machteld; Demerouti, Evangelia; Peeters, Maria|info:eu-repo/dai/nl/07487893X

    2015-01-01

    This quasi-experimental field study examines the effects of an intervention designed to boost job resources, affective well-being, and self-efficacy via job crafting behaviour. Employees (n = 39) in a Dutch police district received a 1-day training, after which they worked towards self-set crafting

  18. Microwave-assisted facile and rapid Friedel-Crafts benzoylation of arenes catalysed by bismuth trifluoromethanesulfonate

    DEFF Research Database (Denmark)

    Tran, Phoung Hoang; Hansen, Poul Erik; Pham, Thuy Than

    2014-01-01

    The catalytic activity of metal triflates was investigated in Friedel–Crafts benzoylation under microwave irradiation. Friedel–Crafts benzoylation with benzoyl chloride of a variety of arenes containing electron-rich and electron-poor rings using bismuth triflate under microwave irradiation is de...

  19. A discussion of the necessity of craft education in the 21st century

    Directory of Open Access Journals (Sweden)

    Eva Veeber

    2015-02-01

    Full Text Available Craft education has held a permanent place in Estonian and Finnish schools, although its value and appreciation have changed over time. The aim of the article is to discuss the necessity of craft education in today’s world and its possible impact on the development of children and adolescents. The discussion seeks an interdisciplinary explanation using three perspectives that complement each other. The first describes the challenges of modern society with respect to individual development and schooling. The second deals with Aaron Antonovsky's theory of generalized resistance resources and an individual's possibility to manage in a stressful society. The third addresses the individual as a developing neurological being, along with the effect of learning and practicing motor skills on the human brain. We conclude that crafts is a multidisciplinary phenomenon, and that learning and practicing crafts promotes the comprehension of diversity and challenges in life. Additionally, educational crafts enriches the learning environment, offering opportunities to develop transferable skills that human beings constantly need in society. In addition, crafts provides a balanced way to come to understand the world and one’s role in it, by simultaneously promoting motor and cognitive development and making unique demands on one’s being.Keywords: crafts, craft education, making, sense of coherence, education, embodiment

  20. 46 CFR 180.202 - Survival craft-vessels operating on oceans routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on oceans routes. 180... VESSELS (UNDER 100 GROSS TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 180.202 Survival craft—vessels operating on oceans routes. (a) Each vessel certificated to operate on...

  1. 46 CFR 117.207 - Survival craft-vessels operating on lakes, bays, and sounds routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-vessels operating on lakes, bays, and... 49 PASSENGERS LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 117.207 Survival craft—vessels operating on lakes, bays, and sounds routes. (a) Each vessel with overnight...

  2. 33 CFR 100.916 - Chris Craft Silver Cup Races, Algonac, MI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Chris Craft Silver Cup Races, Algonac, MI. 100.916 Section 100.916 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.916 Chris Craft Silver Cup...

  3. Shifting Values: The Promotional Policies of Craft and Industrial Design in Flanders (1980-2001)

    NARCIS (Netherlands)

    Gimeno Martinez, J.C.

    2014-01-01

    This article looks at the shifts in cultural promotion of craft as a result of a particular political conjuncture in the region of Flanders (Belgium). In 1991, as a consequence of Belgian federalization, the promotion policies for craft in Flanders passed from being answerable to the Belgian state

  4. 46 CFR 180.208 - Survival craft-vessels operating on rivers routes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on rivers routes. 180... VESSELS (UNDER 100 GROSS TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 180.208 Survival craft—vessels operating on rivers routes. (a) Except as allowed by paragraphs (c), (d...

  5. Design and Craft Education in Iceland, Pedagogical Background and Development: A Literature Review

    Science.gov (United States)

    Olafsson, Brynjar; Thorsteinsson, Gisli

    2009-01-01

    Sloyd pedagogy was introduced towards the close of the 18th century to Icelandic educators. Subsequently craft was established as a specific subject aimed at general education. In the beginning craft was called "school industry," to distinguish it from "home industry" whose aim was to help homes to be self-sufficient for…

  6. "Miss! I'm Done!" Finishing Craft Assignments as a Situated Activity System in Preschool

    Science.gov (United States)

    Deunk, Marjolein; Berenst, Jan; de Glopper, Kees

    2010-01-01

    We describe the Situated Activity System of finishing craft assignments in preschool: the specific, routinized way that child and teacher jointly close the child's craft assignment, employing a specific discourse pattern. We analyzed the interactions of 14 Dutch children between 2.1 and 3.10 years old while they were finishing their craft…

  7. Cultivating Perspectival Acuity: The Value and Cost of Integrating Theory, Craft, Research, and Practice

    Directory of Open Access Journals (Sweden)

    Joe Manganelli

    2016-10-01

    Full Text Available This paper presents reflections on integrating theory, craft, research, and practice to improve the accuracy and resiliency of each. The reflections build toward a set of statements about the value and the cost of integrating theory, craft, research, and practice. Specifically, the authors offer the Privileged Work / Non-Privileged Work Framework and concept of cultivating Perspectival Acuity.

  8. Digitizing Craft: Creative Writing Studies and New Media--A Proposal

    Science.gov (United States)

    Koehler, Adam

    2013-01-01

    This article identifies and examines a digital arm of creative writing studies and organizes that proposal into four categories through which to theorize the "craft" of creative production, each borrowed from Tim Mayers's "(Re)Writing Craft: Composition, Creative Writing, and the Future of English Studies": process, genre, author, and…

  9. Cooking and Hammering: Primary School Pupils' Concepts of Their Craft Skills

    Science.gov (United States)

    Müürsepp, Mare; Kikkull, Andry

    2014-01-01

    The aim of the study is to clear the significance of craft skills for the pupils in age nine and twelve years. More than 200 pupils were asked to define, what are the most important skills for the pupils of their age. The results bring out that category of the skills related to craft subject is of the most presented categories in pupils' self…

  10. Job crafting at the team and individual level: Implications for work engagement and performance

    NARCIS (Netherlands)

    Tims, M.; Bakker, A.B.; Derks, D.; Rhenen, van W.

    2013-01-01

    Previous research suggests that employee job crafting is positively related to job performance through employee work engagement. The present study expands this individual-level perspective to the team level by hypothesizing that team job crafting relates positively to team performance through team

  11. The Influence of Future Time Perspective on Worker Outcomes: The Role of Job Crafting

    NARCIS (Netherlands)

    Kooij, T.A.M.; Tims, M.; Akkermans, J.

    2017-01-01

    This two-wave study aimed to examine future time perspective (FTP) as an antecedent of job crafting, and in turn job crafting as a mediator in associations between FTP and work outcomes. Based on the lifespan socio-emotional selectivity theory, we expected that open-ended and limited FTP would evoke

  12. Workaholism versus work engagement and job crafting : What is the role of self-management strategies?

    NARCIS (Netherlands)

    Zeijen, Marijntje E.L.; Peeters, Maria C.W.; Hakanen, Jari J.

    2018-01-01

    Job crafting refers to the proactive actions employees take to redesign their jobs in order to get a better fit with their competencies, expectations, and wishes. So far, little is known about job crafting's underlying mechanisms. In this study, we examine how two different states of affective

  13. Workaholism versus work engagement and job crafting : What is the role of self-management strategies?

    NARCIS (Netherlands)

    Zeijen, M.; Peeters, M.C.W.; Hakanen, J.

    Job crafting refers to the proactive actions employees take to redesign their jobs in order to get a better fit with their competencies, expectations, and wishes. So far, little is known about job crafting's underlying mechanisms. In this study, we examine how two different states of affective

  14. Report: The New Brunswick Indian Arts and Crafts Association Workshop for Board Members. No. 165.

    Science.gov (United States)

    Goddu, Roland; Nicholas, Darryl

    This is a report on a training session conducted for the board members of the New Brunswick Indian Arts and Crafts Association with the aim of outlining purposes of the Association, and assisting in drawing up plans for a formal administrative structure among arts and crafts organizations. An administrative manual containing terms of reference…

  15. The Development of Indian and Eskimo Art and Crafts in the Far North.

    Science.gov (United States)

    Phillips, R. A. J.; And Others

    The focus of the conference, "The Development of Indian and Eskimo Art and Crafts in the Far North," was the creation of a market for reputable Indian and Eskimo art work on an economically sound basis which would benefit both the native artists and the Canadian economy. Two governmental reports, "Northern Arts and Crafts" and…

  16. The impact of job crafting on job demands, job resources, and well-being

    NARCIS (Netherlands)

    Tims, M.; Bakker, A.B.; Derks, D.

    2013-01-01

    This longitudinal study examined whether employees can impact their own well-being by crafting their job demands and resources. Based on the Job Demands-Resources model, we hypothesized that employee job crafting would have an impact on work engagement, job satisfaction, and burnout through changes

  17. Computer Technology-Integrated Projects Should Not Supplant Craft Projects in Science Education

    Science.gov (United States)

    Klopp, Tabatha J.; Rule, Audrey C.; Schneider, Jean Suchsland; Boody, Robert M.

    2014-01-01

    The current emphasis on computer technology integration and narrowing of the curriculum has displaced arts and crafts. However, the hands-on, concrete nature of craft work in science modeling enables students to understand difficult concepts and to be engaged and motivated while learning spatial, logical, and sequential thinking skills. Analogy…

  18. When craft and science collide: Improving therapeutic practices through evidence-based innovations.

    Science.gov (United States)

    Justice, Laura M

    2010-04-01

    Evidence-based practice (EBP) is a model of clinical decision-making that is increasingly being advocated for use in the field of speech-language pathology. With the increased emphasis on scientific evidence as a form of knowledge important to EBP, clinicians may wonder whether their craft-based knowledge (i.e., knowledge derived from theory and practice), remains a legitimate form of knowledge for use in clinician decisions. This article describes forms of knowledge that may be used to address clinical questions, to include both craft and science. Additionally, the steps used when engaging in EBP are described so that clinicians understand when and how craft comes into play. The major premise addressed within this article is that craft is a legitimate form of knowledge and that engagement in EBP requires one to employ craft-based knowledge.

  19. Leak Detection in Water-Filled Small-Diameter Polyethylene Pipes by Means of Acoustic Emission Measurements

    Directory of Open Access Journals (Sweden)

    Alberto Martini

    2016-12-01

    Full Text Available The implementation of effective strategies to manage leaks represents an essential goal for all utilities involved with drinking water supply in order to reduce water losses affecting urban distribution networks. This study concerns the early detection of leaks occurring in small-diameter customers’ connections to water supply networks. An experimental campaign was carried out in a test bed to investigate the sensitivity of Acoustic Emission (AE monitoring to water leaks. Damages were artificially induced on a polyethylene pipe (length 28 m, outer diameter 32 mm at different distances from an AE transducer. Measurements were performed in both unburied and buried pipe conditions. The analysis permitted the identification of a clear correlation between three monitored parameters (namely total Hits, Cumulative Counts and Cumulative Amplitude and the characteristics of the examined leaks.

  20. 33 CFR 150.515 - What are the requirements for weight testing of newly installed or relocated craft?

    Science.gov (United States)

    2010-07-01

    ... weight testing of newly installed or relocated craft? 150.515 Section 150.515 Navigation and Navigable... testing of newly installed or relocated craft? (a) The operator must perform installation weight testing... (a) of this section, when survival crafts are relocated to another deepwater port. ...

  1. 46 CFR 24.15-5 - Canadian pleasure craft temporarily using navigable waters of the United States.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Canadian pleasure craft temporarily using navigable... SECURITY UNINSPECTED VESSELS GENERAL PROVISIONS Equivalents § 24.15-5 Canadian pleasure craft temporarily using navigable waters of the United States. Uninspected Canadian pleasure craft (uninspected vessels...

  2. 33 CFR 150.503 - What are the time interval requirements for maintenance on survival craft falls?

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What are the time interval requirements for maintenance on survival craft falls? 150.503 Section 150.503 Navigation and Navigable Waters... maintenance on survival craft falls? (a) Each fall used in a launching device for survival craft or rescue...

  3. 46 CFR 25.25-17 - Survival craft requirements for uninspected passenger vessels of at least 100 gross tons.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Survival craft requirements for uninspected passenger... Survival craft requirements for uninspected passenger vessels of at least 100 gross tons. (a) Each uninspected passenger vessel of at least 100 gross tons must have adequate survival craft with enough capacity...

  4. 33 CFR 125.15 - Access to waterfront facilities, and port and harbor areas, including vessels and harbor craft...

    Science.gov (United States)

    2010-07-01

    ..., and port and harbor areas, including vessels and harbor craft therein. 125.15 Section 125.15....15 Access to waterfront facilities, and port and harbor areas, including vessels and harbor craft....09 to those waterfront facilities, and port and harbor areas, including vessels and harbor craft...

  5. 33 CFR 149.303 - What survival craft and rescue boats may be used on a manned deepwater port?

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What survival craft and rescue boats may be used on a manned deepwater port? 149.303 Section 149.303 Navigation and Navigable Waters... craft and rescue boats may be used on a manned deepwater port? (a) Each survival craft on a manned...

  6. 25 CFR 309.24 - How will statements about Indian origin of art or craft products be interpreted?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How will statements about Indian origin of art or craft products be interpreted? 309.24 Section 309.24 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR PROTECTION OF INDIAN ARTS AND CRAFTS PRODUCTS § 309.24 How will statements about Indian origin of...

  7. 77 FR 32985 - Notice of Inventory Completion: U.S. Department of the Interior, Indian Arts and Crafts Board...

    Science.gov (United States)

    2012-06-04

    ... Inventory Completion: U.S. Department of the Interior, Indian Arts and Crafts Board, Museum of the Plains... Plains Indian, Indian Arts and Crafts Board, has completed an inventory of human remains, in consultation..., Indian Arts and Crafts Board. Disposition of the human remains to the Indian tribes stated below may...

  8. Small lung cancers: improved detection by use of bone suppression imaging--comparison with dual-energy subtraction chest radiography.

    Science.gov (United States)

    Li, Feng; Engelmann, Roger; Pesce, Lorenzo L; Doi, Kunio; Metz, Charles E; Macmahon, Heber

    2011-12-01

    To determine whether use of bone suppression (BS) imaging, used together with a standard radiograph, could improve radiologists' performance for detection of small lung cancers compared with use of standard chest radiographs alone and whether BS imaging would provide accuracy equivalent to that of dual-energy subtraction (DES) radiography. Institutional review board approval was obtained. The requirement for informed consent was waived. The study was HIPAA compliant. Standard and DES chest radiographs of 50 patients with 55 confirmed primary nodular cancers (mean diameter, 20 mm) as well as 30 patients without cancers were included in the observer study. A new BS imaging processing system that can suppress the conspicuity of bones was applied to the standard radiographs to create corresponding BS images. Ten observers, including six experienced radiologists and four radiology residents, indicated their confidence levels regarding the presence or absence of a lung cancer for each lung, first by using a standard image, then a BS image, and finally DES soft-tissue and bone images. Receiver operating characteristic (ROC) analysis was used to evaluate observer performance. The average area under the ROC curve (AUC) for all observers was significantly improved from 0.807 to 0.867 with BS imaging and to 0.916 with DES (both P chest radiographs. Further improvements can be achieved by use of DES radiography but with the requirement for special equipment and a potential small increase in radiation dose. © RSNA, 2011.

  9. Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening.

    Science.gov (United States)

    Wagner, Bridget K; Carrinski, Hyman A; Ahn, Young-Hoon; Kim, Yun Kyung; Gilbert, Tamara J; Fomina, Dina A; Schreiber, Stuart L; Chang, Young-Tae; Clemons, Paul A

    2008-04-02

    A small molecule capable of distinguishing the distinct states resulting from cellular differentiation would be of enormous value, for example, in efforts aimed at regenerative medicine. We screened a collection of fluorescent small molecules for the ability to distinguish the differentiated state of a mouse skeletal muscle cell line. High-throughput fluorescence-based screening of C2C12 myoblasts and myotubes resulted in the identification of six compounds with the desired selectivity, which was confirmed by high-content screening in the same cell states. The compound that resulted in the greatest fluorescence intensity difference between the cell states was used as the screening agent in a pilot screen of 84 kinase inhibitors, each present in four doses, for inhibition of myogenesis. Of the kinase inhibitors, 17 resulted in reduction of fluorescence at one or more concentrations; among the "hits" included known inhibitors of myogenesis, confirming that this compound is capable of detecting the differentiated myotube state. We suggest that the strategy of screening for screening agents reported here may be extended more broadly in the future.

  10. Detecting metastasis of gastric carcinoma using high-resolution micro-CT system: in vivo small animal study

    Science.gov (United States)

    Liu, Junting; Tian, Jie; Liang, Jimin; Li, Xiangsi; Yang, Xiang; Chen, Xiaofeng; Chen, Yi; Zhou, Yuanfang; Wang, Xiaorui

    2011-03-01

    Immunocytochemical and immunofluorescence staining are used for identifying the characteristics of metastasis in traditional ways. Micro-computed tomography (micro-CT) is a useful tool for monitoring and longitudinal imaging of tumor in small animal in vivo. In present study, we evaluated the feasibility of the detection for metastasis of gastric carcinoma by high-resolution micro-CT system with omnipaque accumulative enhancement method in the organs. Firstly, a high-resolution micro-CT ZKKS-MCT-sharp micro-CT was developed by our research group and Guangzhou Zhongke Kaisheng Medical Technology Co., Ltd. Secondly, several gastric carcinoma models were established through inoculating 2x106 BGC-823 gastric carcinoma cells subcutaneously. Thirdly, micro-CT scanning was performed after accumulative enhancement method of intraperitoneal injection of omnipaque contrast agent containing 360 mg iodine with a concentration of 350 mg I/ml. Finally, we obtained high-resolution anatomical information of the metastasis in vivo in a BALB/c NuNu nude mouse, the 3D tumor architecture is revealed in exquisite detail at about 35 μm spatial resolution. In addition, the accurate shape and volume of the micrometastasis as small as 0.78 mm3 can be calculated with our software. Overall, our data suggest that this imaging approach and system could be used to enhance the understanding of tumor proliferation, metastasis and could be the basis for evaluating anti-tumor therapies.

  11. [Comparison of detectability of liquid crystal displays (LCDs) and film using phantoms of small adenocarcinomas as abnormalities].

    Science.gov (United States)

    Mochizuki, Yasuo; Abe, Shinji; Monma, Masahiko; Yamaguchi, Kojirou; Adachi, Toshiki

    2011-01-01

    Following the trend of the digitalization of the modalities used for diagnostic imaging, the devices for such imaging have increasingly included monitors. The present study was undertaken to evaluate the usefulness of soft-copy (liquid crystal display; LCD) images of phantoms of small adenocarcinomas using receiver operating characteristic (ROC) analysis of two different display systems: LCD and hard copy (film). A two-tailed paired t-test and the jackknife method (parametric methods) were performed, and no significant differences were found in the area under the ROC curve (AUC) for the pulmonary fields, lungs, ribs, or mediastinum between the film and LCD display systems, and the detectability did not differ between the film and LCD monitors. A Mann-Whitney U test, which is a non-parametric method that applies to the analysis of a small sample, also showed no significant differences in the AUC. The results of this study suggest that LCDs can replace hard-copy film as a display system if the signals.

  12. 77 FR 72999 - Small Brewers Bond Reduction

    Science.gov (United States)

    2012-12-07

    ... 1986 (IRC), pertains to the taxation of distilled spirits, wines, and beer (see title 26 of the United... qualification of breweries, bonds and taxation, removals without payment of tax, and records and reporting..., including the increased number of small (``craft'') brewers. In an advance notice of proposed rulemaking...

  13. Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer

    Directory of Open Access Journals (Sweden)

    Viteri Santiago

    2010-12-01

    Full Text Available Abstract Background Immunohistochemistry (IHC with mutation-specific antibodies may be an ancillary method of detecting EGFR mutations in lung cancer patients. Methods EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non-small-cell lung cancer (NSCLC cell lines and tumor samples from 78 stage IV NSCLC patients. Results IHC correctly identified del 19 in the H1650 and PC9 cell lines, L858R in H1975, and wild-type EGFR in H460 and A549, as well as wild-type EGFR in tumor samples from 22 patients. IHC with the mAb against EGFR with del 19 was highly positive for the protein in all 17 patients with a 15-bp (ELREA deletion in exon 19, whereas in patients with other deletions, IHC was weakly positive in 3 cases and negative in 9 cases. IHC with the mAb against the L858R mutation showed high positivity for the protein in 25/27 (93% patients with exon 21 EGFR mutations (all with L858R but did not identify the L861Q mutation in the remaining two patients. Conclusions IHC with mutation-specific mAbs against EGFR is a promising method for detecting EGFR mutations in NSCLC patients. However these mAbs should be validated with additional studies to clarify their possible role in routine clinical practice for screening EGFR mutations in NSCLC patients.

  14. Study on development and actual application of scientific crime detection technique using small scale neutron radiation source

    International Nuclear Information System (INIS)

    Suzuki, Yasuhiro; Kishi, Toru; Tachikawa, Noboru; Ishikawa, Isamu.

    1997-01-01

    PGA (Prompt γ-ray Analysis) is an analytic method of γ-ray generated from atomic nuclei of elements in the specimen just after irradiation (within 10(exp-14)sec.) of neutron to it. As using neutron with excellent transmission for an exciting source, this method can be used for inspecting the matters in closed containers non-destructively, and can also detect non-destructively light elements such as boron, nitrogen and others difficult by other non-destructive analysis. Especially, it is found that this method can detect such high concentration of nitrogen, chlorine and others which are characteristic elements for the explosives. However, as there are a number of limitations at the nuclear reactor site, development of an analytical apparatus for small scale neutron radiation source was begun, at first. In this fiscal year, analysis of the light elements such as nitrogen, chlorine and others using PGA was attempted by using 252-Cf as the simplest neutron source in its operation. As the 252-Cf neutron flux was considerably lower than that of nuclear reactor, its analytical sensitivity was also investigated. (G.K.)

  15. Universal quantum dot-based sandwich-like immunoassay strategy for rapid and ultrasensitive detection of small molecules using portable and reusable optofluidic nano-biosensing platform

    International Nuclear Information System (INIS)

    Zhou, Liping; Zhu, Anna; Lou, Xuening; Song, Dan; Yang, Rong; Shi, Hanchang; Long, Feng

    2016-01-01

    A universal sandwich-like immunoassay strategy based on quantum-dots immunoprobe (QD-labeled anti-mouse IgG antibody) was developed for rapid and ultrasensitive detection of small molecules. A portable and reusable optofluidic nano-biosensing platform was applied to investigate the sandwich-like immunoassay mechanism and format of small molecules, as well as the binding kinetics between QD immunoprobe and anti-small molecule antibody. A two-step immunoassay method that involves pre-incubation mixture of different concentration of small molecule and anti-small molecule antibody, and subsequent introduction of QD immunoprobe into the optofluidic cell was conducted for small molecule determination. Compared with the one-step immunoassay method, the two-step immunoassay method can obtain higher fluorescence signal and higher sensitivity index, thus improving the nano-biosensing performance. Based on the proposed strategy, two mode targets, namely, microcystin-LR (MC-LR) and Bisphenol A (BPA) were tested with high sensitivity, rapidity, and ease of use. A higher concentration of small molecules in the sample led to less anti-small molecule antibody bound with antigen-carrier protein conjugate immobilized onto the sensor surface, and less QD immunoprobes bound with anti-small molecule antibody. This phenomenon lowered the fluorescence signal detected by nano-biosensing platform. Under optimal operating conditions, MC-LR and BPA exhibited a limit of detection of 0.003 and 0.04 μg/L, respectively. The LODs were better than those of the indirect competitive immunoassay method for small molecules via Cy5.5-labeled anti-small molecule antibody. The proposed QD-based sandwich-like immunoassay strategy was evaluated in spiked water samples, and showed good recovery, precision and accuracy without complicated sample pretreatments. All these results demonstrate that the new detection strategy could be readily applied to the other trace small molecules in real water samples

  16. Evaluation of a computer-aided detection algorithm for timely diagnosis of small acute intracranial hemorrhage on computed tomography in a critical care environment

    Science.gov (United States)

    Lee, Joon K.; Chan, Tao; Liu, Brent J.; Huang, H. K.

    2009-02-01

    Detection of acute intracranial hemorrhage (AIH) is a primary task in the interpretation of computed tomography (CT) brain scans of patients suffering from acute neurological disturbances or after head trauma. Interpretation can be difficult especially when the lesion is inconspicuous or the reader is inexperienced. We have previously developed a computeraided detection (CAD) algorithm to detect small AIH. One hundred and thirty five small AIH CT studies from the Los Angeles County (LAC) + USC Hospital were identified and matched by age and sex with one hundred and thirty five normal studies. These cases were then processed using our AIH CAD system to evaluate the efficacy and constraints of the algorithm.

  17. Universal quantum dot-based sandwich-like immunoassay strategy for rapid and ultrasensitive detection of small molecules using portable and reusable optofluidic nano-biosensing platform

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Liping; Zhu, Anna; Lou, Xuening; Song, Dan; Yang, Rong [School of Environment and Natural Resources, Renmin University of China, Beijing (China); Shi, Hanchang [School of Environment, Tsinghua University, Beijing (China); Long, Feng, E-mail: longf04@ruc.edu.cn [School of Environment and Natural Resources, Renmin University of China, Beijing (China)

    2016-01-28

    A universal sandwich-like immunoassay strategy based on quantum-dots immunoprobe (QD-labeled anti-mouse IgG antibody) was developed for rapid and ultrasensitive detection of small molecules. A portable and reusable optofluidic nano-biosensing platform was applied to investigate the sandwich-like immunoassay mechanism and format of small molecules, as well as the binding kinetics between QD immunoprobe and anti-small molecule antibody. A two-step immunoassay method that involves pre-incubation mixture of different concentration of small molecule and anti-small molecule antibody, and subsequent introduction of QD immunoprobe into the optofluidic cell was conducted for small molecule determination. Compared with the one-step immunoassay method, the two-step immunoassay method can obtain higher fluorescence signal and higher sensitivity index, thus improving the nano-biosensing performance. Based on the proposed strategy, two mode targets, namely, microcystin-LR (MC-LR) and Bisphenol A (BPA) were tested with high sensitivity, rapidity, and ease of use. A higher concentration of small molecules in the sample led to less anti-small molecule antibody bound with antigen-carrier protein conjugate immobilized onto the sensor surface, and less QD immunoprobes bound with anti-small molecule antibody. This phenomenon lowered the fluorescence signal detected by nano-biosensing platform. Under optimal operating conditions, MC-LR and BPA exhibited a limit of detection of 0.003 and 0.04 μg/L, respectively. The LODs were better than those of the indirect competitive immunoassay method for small molecules via Cy5.5-labeled anti-small molecule antibody. The proposed QD-based sandwich-like immunoassay strategy was evaluated in spiked water samples, and showed good recovery, precision and accuracy without complicated sample pretreatments. All these results demonstrate that the new detection strategy could be readily applied to the other trace small molecules in real water samples

  18. Detecting small gravity change in field measurement: simulations and experiments of the superconducting gravimeter—iGrav

    International Nuclear Information System (INIS)

    Kao, Ricky; Kabirzadeh, Hojjat; Kim, Jeong Woo; Neumeyer, Juergen; Sideris, Michael G

    2014-01-01

    In order to detect small gravity changes in field measurements, such as with CO 2  storage, we designed simulations and experiments to validate the capabilities of the iGrav superconducting gravimeter. Qualified data processing was important to obtain the residual gravity from the iGrav's raw gravity signals, without the tidal components, atmosphere, polar motion and hydrological effects. Two simulations and four designed experiments are presented in this study. The first simulation detected the gravity change during CO 2  injection. The residual gravity of CO 2  leakage was targeted with the second simulation from the main storage reservoir to secondary space underground. The designed experiments monitored the situation of gravity anomalies in the iGrav's records. These tests focused on short-term gravity anomalies, such as gravity changes, step functions, repeat observations and gradient measurements from the iGrav, rather than on long-term tidal effects. The four laboratory experiments detected a decrease in gravity of −0.56 ± 0.15 µGal (10 −8  m s −2 ) with a 92.8 kg weight on the top of the iGrav. A step function occurred in the gravity signals, when the tilt control was out of balance. We also used a professional camera dolly with a track to observe repeated horizontal movements and an electric lift table for controlled vertical movements to measure the average gradient of −2.67 ± 0.01 µGal cm −1 . (paper)

  19. High Resolution Melting Analysis for Detecting p53 Gene Mutations in Patients with Non-small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Zhihong CHEN

    2011-10-01

    Full Text Available Background and objective It has been proven that p53 gene was related to many human cancers. The mutations in p53 gene play an important role in carcinogensis and mostly happened in exon 5-8. The aim of this study is to establish a high resolution melting (HRM assay to detect p53 mutations from patients with non-small cell lung cancer (NSCLC, to investigate the characteristics of p53 gene mutations, and to analyze the relationship between p53 mutations and evolution regularity of pathogenesis. Methods p53 mutations in exon 5-8 were detected by HRM assay on DNA insolated from 264 NSCLC samples derived from tumor tissues and 54 control samples from pericancerous pulmonary tissues. The mutation samples by the HRM assay were confirmed by sequencing technique. Samples which were positive by HRM but wild type by sequencing were further confirmed by sub-clone and sequencing. Results No mutation was found in 54 pericancerous pulmonary samples by HRM assay. 104 of the 264 tumor tissues demonstrated mutation curves by HRM assay, 102 samples were confirmed by sequencing, including 95 point mutations and 7 frame shift mutations by insertion or deletion. The mutation rate of p53 gene was 39.4%. The mutation rate from exon 5-8 were 11.7%, 8%, 12.5% and 10.6%, respectively and there was no statistically significant difference between them (P=0.35. p53 mutations were significantly more frequent in males than that in females, but not related to the other clinicopathologic characteristics. Conclusion The results indicate that HRM is a sensitive in-tube methodology to detect for mutations in clinical samples. The results suggest that the arising p53 mutations in NSCLC may be due to spontaneous error in DNA synthesis and repair.

  20. Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non-small-cell lung cancer.

    Science.gov (United States)

    Pailler, Emma; Adam, Julien; Barthélémy, Amélie; Oulhen, Marianne; Auger, Nathalie; Valent, Alexander; Borget, Isabelle; Planchard, David; Taylor, Melissa; André, Fabrice; Soria, Jean Charles; Vielh, Philippe; Besse, Benjamin; Farace, Françoise

    2013-06-20

    The diagnostic test for ALK rearrangement in non-small-cell lung cancer (NSCLC) for crizotinib treatment is currently done on tumor biopsies or fine-needle aspirations. We evaluated whether ALK rearrangement diagnosis could be performed by using circulating tumor cells (CTCs). The presence of an ALK rearrangement was examined in CTCs of 18 ALK-positive and 14 ALK-negative patients by using a filtration enrichment technique and filter-adapted fluorescent in situ hybridization (FA-FISH), a FISH method optimized for filters. ALK-rearrangement patterns were determined in CTCs and compared with those present in tumor biopsies. ALK-rearranged CTCs and tumor specimens were characterized for epithelial (cytokeratins, E-cadherin) and mesenchymal (vimentin, N-cadherin) marker expression. ALK-rearranged CTCs were monitored in five patients treated with crizotinib. All ALK-positive patients had four or more ALK-rearranged CTCs per 1 mL of blood (median, nine CTCs per 1 mL; range, four to 34 CTCs per 1 mL). No or only one ALK-rearranged CTC (median, one per 1 mL; range, zero to one per 1 mL) was detected in ALK-negative patients. ALK-rearranged CTCs harbored a unique (3'5') split pattern, and heterogeneous patterns (3'5', only 3') of splits were present in tumors. ALK-rearranged CTCs expressed a mesenchymal phenotype contrasting with heterogeneous epithelial and mesenchymal marker expressions in tumors. Variations in ALK-rearranged CTC levels were detected in patients being treated with crizotinib. ALK rearrangement can be detected in CTCs of patients with ALK-positive NSCLC by using a filtration technique and FA-FISH, enabling both diagnostic testing and monitoring of crizotinib treatment. Our results suggest that CTCs harboring a unique ALK rearrangement and mesenchymal phenotype may arise from clonal selection of tumor cells that have acquired the potential to drive metastatic progression of ALK-positive NSCLC.

  1. Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors.

    Directory of Open Access Journals (Sweden)

    Tao Cui

    Full Text Available BACKGROUND: Small intestine neuroendocrine tumors (SI-NETs belong to a rare group of cancers. Most patients have developed metastatic disease at the time of diagnosis, for which there is currently no cure. The delay in diagnosis is a major issue in the clinical management of the patients and new markers are urgently needed. We have previously identified paraneoplastic antigen Ma2 (PNMA2 as a novel SI-NET tissue biomarker. Therefore, we evaluated whether Ma2 autoantibodies detection in the blood stream is useful for the clinical diagnosis and recurrence of SI-NETs. METHODOLOGY/PRINCIPAL FINDINGS: A novel indirect ELISA was set up to detect Ma2 autoantibodies in blood samples of patients with SI-NET at different stages of disease. The analysis was extended to include typical and atypical lung carcinoids (TLC and ALC, to evaluate whether Ma2 autoantibodies in the blood stream become a general biomarker for NETs. In total, 124 blood samples of SI-NET patients at different stages of disease were included in the study. The novel Ma2 autoantibody ELISA showed high sensitivity, specificity and accuracy with ROC curve analysis underlying an area between 0.734 and 0.816. Ma2 autoantibodies in the blood from SI-NET patients were verified by western blot and sequential immunoprecipitation. Serum antibodies of patients stain Ma2 in the tumor tissue and neurons. We observed that SI-NET patients expressing Ma2 autoantibody levels below the cutoff had a longer progression and recurrence-free survival compared to those with higher titer. We also detected higher levels of Ma2 autoantibodies in blood samples from TLC and ALC patients than from healthy controls, as previously shown in small cell lung carcinoma samples. CONCLUSION: Here we show that high Ma2 autoantibody titer in the blood of SI-NET patients is a sensitive and specific biomarker, superior to chromogranin A (CgA for the risk of recurrence after radical operation of these tumors.

  2. Low-cost silicon wafer dicing using a craft cutter

    KAUST Repository

    Fan, Yiqiang

    2014-05-20

    This paper reports a low-cost silicon wafer dicing technique using a commercial craft cutter. The 4-inch silicon wafers were scribed using a crafter cutter with a mounted diamond blade. The pre-programmed automated process can reach a minimum die feature of 3 mm by 3 mm. We performed this scribing process on the top polished surface of a silicon wafer; we also created a scribing method for the back-unpolished surface in order to protect the structures on the wafer during scribing. Compared with other wafer dicing methods, our proposed dicing technique is extremely low cost (lower than $1,000), and suitable for silicon wafer dicing in microelectromechanical or microfluidic fields, which usually have a relatively large die dimension. The proposed dicing technique is also usable for dicing multiple project wafers, a process where dies of different dimensions are diced on the same wafer.

  3. Professional Interventions as a State-Crafting Grammar

    DEFF Research Database (Denmark)

    Ydesen, Christian; Øland, Trine

    2015-01-01

    of reasoning. The second part titled ‘Theoretical concepts: State, Profession, Immigrant’ aims at presenting and clarifying the triad ‘state – profession – immigrant’ through the conceptual lens of state as a bureaucratic field and state-crafting. The third part designated ‘Working with historical sources......The first part under the headline ‘Theory and the construction of the research object’ will clarify our concept of theory and the Bourdieusian and Wacquantian way of working with theory and theoretical constructions when doing empirical and historical work as basis for the article’s chain......’ consists of three subsections altogether. The first addresses in brief the question of putting the theoretical model into work empirically focussing on the concept of field to avoid determinism and presentism when working with a com-prehensive theoretical framework. The second and third subsections takes...

  4. Understanding and crafting the mix the art of recording

    CERN Document Server

    Moylan, William

    2014-01-01

    Understanding and Crafting the Mix, 3rd edition provides the framework to identify, evaluate, and shape your recordings with clear and systematic methods. Featuring numerous exercises, this third edition allows you to develop critical listening and analytical skills to gain greater control over the quality of your recordings. Sample production sequences and descriptions of the recording engineer's role as composer, conductor, and performer provide you with a clear view of the entire recording process. Dr. William Moylan takes an inside look into a range of iconic popular music, thus offering insights into making meaningful sound judgments during recording. His unique focus on the aesthetic of recording and mixing will allow you to immediately and artfully apply his expertise while at the mixing desk. A companion website features recorded tracks to use in exercises, reference materials, additional examples of mixes and sound qualities, and mixed tracks.

  5. Crafting Sustainable Development Solutions: Frugal Innovations of Grassroots Entrepreneurs

    Directory of Open Access Journals (Sweden)

    Mario Pansera

    2016-01-01

    Full Text Available A shift in the entrepreneurial landscape is taking place brought about by grassroots innovators with little formal education and technological knowhow, living and working in penurious environments. This research represents an emerging third wave of literature on Bottom of the Pyramid innovation, where products are offered for and by the underserved. Using primary and secondary data derived from four cases of grassroots entrepreneurs in the Indian Subcontinent, the study explores the phenomenon where resource scarce entrepreneurs craft solutions that are environmental friendly, with low overall ownership costs, and use locally available material. We argue that the grassroots phenomenon can be fruitfully exploited to achieve the new Sustainable Development Goals proposed by the UN as a post-2015 strategy for the future of global governance. These innovations might have a tremendous impact not only in terms of serving unmet and ignored consumer needs, but also longer term impacts through enhanced productivity, sustainability, poverty reduction and inclusion promotion.

  6. Design- and Craft thinking analysed as Embodied Cognition

    Directory of Open Access Journals (Sweden)

    Camilla Groth

    2016-06-01

    Full Text Available Through the concept of design thinking the act of designing is presented as an intellectual activity, and the act of planning the design is elevated over the making process. However, the importance of materiality and the embodied sense-making that occurs in this context should not be forgotten. In this study, embodied cognition in design and craft practices was investigated through three case studies. The study takes on an enhanced tactile perspective as a methodological platform; thus, the cases involve 1 deafblind makers in ceramics, 2 a practice-led self-study report on tactile experiences while working with clay and 3 a study on design students’ use of their tactile sense during material exploration. The results show that the act of thinking design involves the body as a knowledge provider.

  7. Multipurpose stabilization of the advanced marine surface crafts

    Directory of Open Access Journals (Sweden)

    Sevostyanov Ruslan A.

    2016-01-01

    Full Text Available Advanced marine surface crafts, such as SWATHs, catamarans or hovercrafts become more and more popular for a great range of various tasks. They usually operate at much higher speed than conventional ships. Moreover, in the open sea there are a lot of requirements and restrictions concerning the quality of such crafts’ dynamics, especially in case of the wind or waves. This paper considers application of the control law with a special multipurpose structure for autopilot design for amphibious air cushion vehicles. Such control law allows to decompose the autopilot task into simpler optimization subtasks. Efficiency of this approach is shown in the task of stabilizing yaw angle of the air cushion vehicle in the different weather conditions.

  8. A Small Leak Detection Method Based on VMD Adaptive De-Noising and Ambiguity Correlation Classification Intended for Natural Gas Pipelines.

    Science.gov (United States)

    Xiao, Qiyang; Li, Jian; Bai, Zhiliang; Sun, Jiedi; Zhou, Nan; Zeng, Zhoumo

    2016-12-13

    In this study, a small leak detection method based on variational mode decomposition (VMD) and ambiguity correlation classification (ACC) is proposed. The signals acquired from sensors were decomposed using the VMD, and numerous components were obtained. According to the probability density function (PDF), an adaptive de-noising algorithm based on VMD is proposed for noise component processing and de-noised components reconstruction. Furthermore, the ambiguity function image was employed for analysis of the reconstructed signals. Based on the correlation coefficient, ACC is proposed to detect the small leak of pipeline. The analysis of pipeline leakage signals, using 1 mm and 2 mm leaks, has shown that proposed detection method can detect a small leak accurately and effectively. Moreover, the experimental results have shown that the proposed method achieved better performances than support vector machine (SVM) and back propagation neural network (BP) methods.

  9. A Small Leak Detection Method Based on VMD Adaptive De-Noising and Ambiguity Correlation Classification Intended for Natural Gas Pipelines

    Directory of Open Access Journals (Sweden)

    Qiyang Xiao

    2016-12-01

    Full Text Available In this study, a small leak detection method based on variational mode decomposition (VMD and ambiguity correlation classification (ACC is proposed. The signals acquired from sensors were decomposed using the VMD, and numerous components were obtained. According to the probability density function (PDF, an adaptive de-noising algorithm based on VMD is proposed for noise component processing and de-noised components reconstruction. Furthermore, the ambiguity function image was employed for analysis of the reconstructed signals. Based on the correlation coefficient, ACC is proposed to detect the small leak of pipeline. The analysis of pipeline leakage signals, using 1 mm and 2 mm leaks, has shown that proposed detection method can detect a small leak accurately and effectively. Moreover, the experimental results have shown that the proposed method achieved better performances than support vector machine (SVM and back propagation neural network (BP methods.

  10. Striving towards improved Friedel-Crafts acylation catalysts

    International Nuclear Information System (INIS)

    Scott, N.M.; Deacon, G.B.

    1998-01-01

    Full text: Lanthanum, ytterbium and scandium salts of trifluoromethanesulfonic acid have been shown to act as promising Lewis acid catalysts for the Friedel-Craft acylation reactions. In our study catalytic acylation of anisole by acetic anhydride in nitroethane was investigated. Yields were determined after extraction of para-methoxyacetophenone from the reaction mixture by G.L.C using the external standardisation method. Anhydrous lanthanoid tris-triflate salts [Ln(O 3 SCF 3 ) 3 , Ln La, Y, Nd, Eu and Yb] were initially investigated as catalysts. Ytterbium tris-triflate was found to be the most effective giving ∼90% of the acylation product. The hydrated lanthanide tris-nitrate salts [Ln(NO 3 ) 3 .nH 2 O, Ln = La, Nd, Eu and Yb] were also investigated using in situ dehydration with acetic anhydride. These were found to have low solubility in the reaction mixture and gave poor yields of para-methoxyacetophenone. The formation of side products was suggested by the low total recovery of anisole and para-methoxyacetophenone. The blocking of coordination sites of these catalysts by tetraglyme resulted in a 50% reduction in acylation activity compared with the simple salt. Addition of Li(O 3 SCF 3 ) to Ln(O 3 SCF 3 ) 3 catalysts (ratio of 4:1)had only a slight accelerating effect on the Friedel-Crafts acylation reaction and the yield was only marginally greater than that in the absence of the added salt. In contrast Li(ClO 4 ) dramatically decreased reaction times and improved the yield of para-methoxyace-tophenone, as recently reported

  11. The impact of job crafting on job demands, job resources, and well-being.

    Science.gov (United States)

    Tims, Maria; Bakker, Arnold B; Derks, Daantje

    2013-04-01

    This longitudinal study examined whether employees can impact their own well-being by crafting their job demands and resources. Based on the job demands-resources model, we hypothesized that employee job crafting would have an impact on work engagement, job satisfaction, and burnout through changes in job demands and job resources. Data was collected in a chemical plant at three time points with one month in between the measurement waves (N = 288). The results of structural equation modeling showed that employees who crafted their job resources in the first month of the study showed an increase in their structural and social resources over the course of the study (2 months). This increase in job resources was positively related to employee well-being (increased engagement and job satisfaction, and decreased burnout). Crafting job demands did not result in a change in job demands, but results revealed direct effects of crafting challenging demands on increases in well-being. We conclude that employee job crafting has a positive impact on well-being and that employees therefore should be offered opportunities to craft their own jobs.

  12. Legal and economic implications of the German Craft Code Amendment 2004

    Directory of Open Access Journals (Sweden)

    Wolfgang Benzel

    2012-01-01

    Full Text Available As the main reason for initiating an amendment of the Trade and Crafts Code in 2004 was the decrease in the number of companies in general and the number of skilled crafts enterprises in particular and was also due to the fact that the number of employees in the skilled crafts sector had constantly fallen and many companies were not able to find a successor, it was the declared aim of the amendment to counter this structural crisis as well as reducing illegal employment and removing native discrimination. This would then ensure a higher level of employment especially through new company formations and takeovers of existing companies.In addition to providing an important contribution towards the assessment of the basic success of the 2004 Trade and Crafts Code amendment, the results can therefore be used at an international level for discussions on skilled crafts legislation outside Germany. As German skilled crafts legislation developed in a completely different manner from skilled crafts legislation in most other European countries, this aspect is particularly significant and it is conceivable that the results will be useful beyond the borders of the Federal Republic of Germany. The research findings will also be important in determining the limits of deregulation and when it can be considered counterproductive from an economic point of view.

  13. Analyzing components of Community Reinforcement and Family Training (CRAFT): Is treatment entry training sufficient?

    Science.gov (United States)

    Kirby, Kimberly C; Benishek, Lois A; Kerwin, MaryLouise E; Dugosh, Karen L; Carpenedo, Carolyn M; Bresani, Elena; Haugh, James A; Washio, Yukiko; Meyers, Robert J

    2017-11-01

    Community Reinforcement and Family Training (CRAFT) assists family members with a treatment-resistant loved one. The most consistent outcome of CRAFT is increased treatment entry of the identified treatment-resistant person (IP). This led us to question whether all 6 components of CRAFT are necessary. In a randomized clinical trial, 115 concerned significant others (CSOs) of an IP received 12-14 sessions of the full CRAFT intervention, 4-6 sessions focused on Treatment Entry Training (TEnT), or 12-14 sessions of Al-Anon/Nar-Anon Facilitation (ANF). We monitored treatment entry, attendance, and substance use of the IP and the CSO's mood and functioning. Data were collected at baseline and 4, 6, and 9 months after the baseline. We found significant reductions in time to treatment entry (χ(2)2 = 8.89, p = .01) and greater treatment entry rates for CRAFT (62%; odds ratio [OR] = 2.7, 95% confidence interval [CI] = 1.1-6.9) and TEnT (63%; OR = 2.9, 95% CI = 1.2-7.5) compared with ANF (37%), but CRAFT and TEnT did not differ significantly from each other (OR = 1.1, 95% CI = 0.4-2.7). No between-group differences in IP drug use were reported by CSOs, but days of drug use decreased over time for all groups (F(3, 277) = 13.47, p CRAFT produces greater treatment entry rates than ANF and found similar treatment entry rates for CRAFT and TEnT. This suggests that treatment entry training is sufficient for producing the best established outcome of CRAFT. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  14. Self-crafting vegetable snacks: testing the IKEA-effect in children.

    Science.gov (United States)

    Raghoebar, Sanne; van Kleef, Ellen; de Vet, Emely

    2017-01-01

    The purpose of this paper is to test whether the IKEA-effect (Norton et al. , 2012) - better liking for self-crafted products than for identical products crafted by others - can be exploited to increase liking and consumption of vegetable snacks in children. A between-subjects experiment was conducted at an after school care facility. In total, 86 children aged four to six either crafted a peacock with vegetables or with non-food objects following an example. After the task, children ate snack vegetables ad libitum, and rated their liking for the vegetables and pride in crafting the peacock. No significant main effect of the vegetable snack creation on consumption and liking was observed. Also, perceived pride did not mediate the effect of self-crafting vegetable snacks on consumption of and liking for vegetables. Vegetable consumption did not differ between children who were either simply exposed to vegetable snacks while crafting or those who were crafting the vegetable snacks themselves. The equal consumption might suggest that this is caused by simple exposure, but more research is needed comparing self-crafting and exposure to a condition where there is no initial exposure to vegetables. Although the IKEA-effect has been demonstrated in adults, this is one of the first studies evaluating the IKEA-effect in children and as a means to increase liking for a generally disliked product in this target group, i.e. vegetables. The IKEA-effect could not be replicated under these more stringent conditions, where the experimental set-up enabled disentangling exposure and crafting effects.

  15. High Job Demands, Still Engaged and Not Burned Out? The Role of Job Crafting.

    Science.gov (United States)

    Hakanen, Jari J; Seppälä, Piia; Peeters, Maria C W

    2017-08-01

    Traditionally, employee well-being has been considered as resulting from decent working conditions arranged by the organization. Much less is known about whether employees themselves can make self-initiated changes to their work, i.e., craft their jobs, in order to stay well, even in highly demanding work situations. The aim of this study was to use the job demands-resources (JD-R model) to investigate whether job crafting buffers the negative impacts of four types of job demands (workload, emotional dissonance, work contents, and physical demands) on burnout and work engagement. A questionnaire study was designed to examine the buffering role of job crafting among 470 Finnish dentists. All in all, 11 out of 16 possible interaction effects of job demands and job crafting on employee well-being were significant. Job crafting particularly buffered the negative effects of job demands on burnout (7/8 significant interactions) and to a somewhat lesser extent also on work engagement (4/8 significant interactions). Applying job crafting techniques appeared to be particularly effective in mitigating the negative effects of quantitative workload (4/4 significant interactions). By demonstrating that job crafting can also buffer the negative impacts of high job demands on employee well-being, this study contributed to the JD-R model as it suggests that job crafting may even be possible under high work demands, and not only in resourceful jobs, as most previous studies have indicated. In addition to the top-down initiatives for improving employee well-being, bottom-up approaches such as job crafting may also be efficient in preventing burnout and enhancing work engagement.

  16. Arts and Crafts Classes in Years I–III, Based on Methods Featuring Pupils’ Practical Activities

    OpenAIRE

    Piwowarska, Ewa

    2016-01-01

    The issue to be analysed here concerns teachers’ planning of arts and crafts classes in Years I–III, with specific reference to methods featuring pupils’ practical activities. A theoretical part briefly presents the concepts involved in teaching a subject that was initially defined as drawing, then as arts and crafts education, and finally as arts and crafts classes. It points out the factors that influence the process of stimulating pupils’ artistic activities. The technique used in the cour...

  17. Use your eyes - metallographic versus superficial traces of the crafting of Bronze Age ornaments

    DEFF Research Database (Denmark)

    Nørgaard, Heide Wrobel

    and superficial archaeological examinations can be used to understand prehistoric craft. Furthermore, it will show that with an intensive knowledge about previous scientific investigations the superficial traces preserved can reveal a great amount of information and could talk for themselves. Taking as an example...... the early and middle Bronze Age bronze ornaments from North Germany, superficial traces of the metal crafting process, visible with the naked eye, will be compared with metallographic images. The aim of this presentation is to give an overview over the crafting traces everybody could see (with a bit...

  18. The effects of job crafting on subjective well-being amongst South African high school teachers

    Directory of Open Access Journals (Sweden)

    Sergio Peral

    2016-09-01

    Full Text Available Orientation: Job crafting can result in a number of positive outcomes for teachers, such as increased meaningfulness and engagement at work. Increased work engagement and psychological meaningfulness may yield positive benefits for the practice of teaching, thus highlighting the pivotal role of job crafting. Research purpose: The study’s aim was to investigate the relationship between job crafting and subjective well-being amongst South African high school teachers. Subjective well-being comprises psychological meaningfulness and work engagement. The potential mediating effect that psychological meaningfulness had on this relationship was further explored. Motivation for the study: Being in a highly stressful occupation, teachers need to continuously find ways to craft their working practices in order to deal effectively with their job demands and to capitalise on their available job resources. Furthermore, South Africa’s current education system calls for serious proactive measures to be taken to improve and rectify the current status, such as job crafting. Research approach, design and method: A quantitative, cross-sectional survey design was used and administered to a sample of South African high school teachers situated in Gauteng, South Africa (N = 251. Main findings: A positive relationship was found between job crafting (increasing structural resources and challenging job demands and work engagement. Furthermore, psychological meaningfulness mediated the relationship between job crafting and work engagement amongst the sampled high school teachers. Practical/managerial implications: Teachers who craft their work to better suit their preferences and needs will obtain greater meaning in their work and experience increased levels of work engagement. Training programmes and/or group-based interventions targeted around job crafting techniques may be particularly useful in the South African teaching context. Contribution/value-add: This

  19. Taking control: Is job crafting related to the intention to leave surgical training?

    Science.gov (United States)

    Dominguez, Luis Carlos; Stassen, Laurents; de Grave, Willem; Sanabria, Alvaro; Alfonso, Edgar; Dolmans, Diana

    2018-01-01

    The intention to leave surgical training, hereinafter referred as proxy of "attrition," is associated with poor well-being in the workplace. Attrition is suggested to diminish when residents possess job-crafting skills, that is, the ability to redefine their job in meaningful ways and maximize well-being at work by increasing structural and social resources and challenges and decreasing hindering demands. However, the evidence supporting this relationship is scant. This study sought to: 1) investigate to what extent residents possess job-crafting skills and compare residents' levels of job-crafting skills across years of residency training; 2) investigate the relationship between job crafting, well-being as measured by burnout and work-engagement rates, and the intention to leave; and 3) compare the levels of job-crafting skills and well-being between residents with and without serious intentions to leave. This cross sectional study was conducted in fifteen residency programs in Colombia. Surgical residents completed different questionnaires including the Dutch Job Crafting Scale (DJCS), MBI-Human Services Survey (MBI-HSS), Utrecht Work Engagement Scale (UWES-17) and an adapted version of the Nurse Turnover Intention Scale (NTIS). The objectives were addressed by independent analyses of variance (ANOVA), structural equation modeling techniques (SEM) and independent t-tests, respectively. A total of 202 residents participated. Residents generally scored high on their job-crafting skills to increase structural and social resources as well as challenging demands, but were less positive about their skills to reduce hindering demands. No differences across years of training were found. Job crafting correlated positively with work-engagement, which was inversely related to the intention to leave. Conversely, job crafting correlated negatively with burnout, which bore a positive relationship to the intention to leave. Residents with serious intentions to leave exhibited

  20. The capsule endoscopy "suspected blood indicator" (SBI) for detection of active small bowel bleeding: no active bleeding in case of negative SBI.

    Science.gov (United States)

    Tal, Andrea Oliver; Filmann, Natalie; Makhlin, Konstantin; Hausmann, Johannes; Friedrich-Rust, Mireen; Herrmann, Eva; Zeuzem, Stefan; Albert, Jörg G

    2014-09-01

    Capsule endoscopy (CE) is the gold standard to diagnose small bowel bleeding. The "suspected blood indicator" (SBI) offers an automated detection of active small bowel bleeding but validity of this technique is unknown. The objective was to analyze specificity and sensitivity of the SBI using the second small bowel capsule generation for the detection of active bleeding. This is a retrospective analysis of all patients (199) who attended our clinic for CE from June 2008 through March 2013. The second-generation PillCam SB 2 capsule was used for detection of (1) luminal blood content and (2) potentially responsible small bowel lesions. The findings of an independent investigator were correlated to SBI findings and a number of SBI markings were analyzed by a receiver operating characteristic (ROC). In 157/199 cases, no sign of active bleeding or altered blood was detected. One hundred and thirty-seven of these 157 cases provided at least one SBI marking and a mean of 18.4 positive SBI markings per record were found. In 20 cases, neither SBI nor the human investigator detected abnormalities. Thirteen patients showed investigator-detected minor bleeding with mean SBI findings of 36 positive screenshots per record. When major bleeding was diagnosed by the investigator (n = 29), SBI detected a mean of 46.6 SBI-positive markings. SBI turned positive in 179 patients, whereas the investigator detected active bleeding in 42 cases. All patients with active bleeding were detected by SBI (sensitivity 100%, specificity 13%). ROC analysis revealed 51.0 SBI markings being the optimal cutoff for active versus no bleeding (sensitivity 79.1%, specificity 90.4%, misclassification of 15.3%). The new SBI software is a reliable tool to exclude active bleeding and/or major lesions but analysis of the CE video by a trained investigator is still important for the detection of lesions responsible for past bleeding.