Dynamics study of free volume properties of SMA/SMMA blends by PAL method

International Nuclear Information System (INIS)

Jiang, Z.Y.; Jiang, X.Q.; Huang, Y.J.; Lin, J.; Li, S.M.; Li, S.Z.; Hsia, Y.F.

2006-01-01

Miscibility of poly(styrene-co-maleic anhydride) (containing 7 wt% maleic anhydride)/poly(styrene-co-methyl methacrylate) (containing 40 wt% styrene) blends were previously studied. It was obtained that SMA70 (containing 70 wt% of SMA in SMA/SMMA blends) is miscible in molecular level but SMA20 is not. In this paper, the two blends selected were used to investigate the temperature dependence of free volume parameters. It showed there are different deviations of free volume parameters in SMA20 and SMA70, and it was interesting that temperature dependence of ortho-positronium lifetime τ 3 of the SMA20 mixture exhibits two breaks in the range temperature from 90 deg. C to 120 deg. C, which revealed that the mixture has two glass transition ranges. Also, ortho-positronium lifetime τ 3 of the SMA20 mixture is nearly constant in the temperature range from 130 deg. C to 160 deg. C. These indicated that SMA20 blend is phase-separated in room temperature and become miscible above 130 deg. C, which may be due to steric hindrance effect of phenyl rings of SMMA and SMA. From the deviation of o-Ps lifetimes of SMA70, the single glass transition temperature of SMA70 blend was shown. Combining the previous study, it was further concluded that PAL method seems to be a powerful method to detect in situ phase behavior of immiscible polymer blends and glass transition of miscible polymer blends

Adaptive and energy efficient SMA-based handling systems

Science.gov (United States)

Motzki, P.; Kunze, J.; Holz, B.; York, A.; Seelecke, S.

2015-04-01

Shape Memory Alloys (SMA's) are known as actuators with very high energy density. This fact allows for the construction of very light weight and energy-efficient systems. In the field of material handling and automated assembly process, the avoidance of big moments of inertia in robots and kinematic units is essential. High inertial forces require bigger and stronger robot actuators and thus higher energy consumption and costs. For material handling in assembly processes, many different individual grippers for various work piece geometries are used. If one robot has to handle different work pieces, the gripper has to be exchanged and the assembly process is interrupted, which results in higher costs. In this paper, the advantages of using high energy density Shape Memory Alloy actuators in applications of material-handling and gripping-technology are explored. In particular, light-weight SMA actuated prototypes of an adaptive end-effector and a vacuum-gripper are constructed via rapid-prototyping and evaluated. The adaptive end-effector can change its configuration according to the work piece geometry and allows the handling of multiple different shaped objects without exchanging gripper tooling. SMA wires are used to move four independent arms, each arm adds one degree of freedom to the kinematic unit. At the tips of these end-effector arms, SMA-activated suction cups can be installed. The suction cup prototypes are developed separately. The flexible membranes of these suction cups are pulled up by SMA wires and thus a vacuum is created between the membrane and the work piece surface. The self-sensing ability of the SMA wires are used in both prototypes for monitoring their actuation.

Energy-dissipating and self-repairing SMA-ECC composite material system

International Nuclear Information System (INIS)

Li, Xiaopeng; Li, Mo; Song, Gangbing

2015-01-01

Structural component ductility and energy dissipation capacity are crucial factors for achieving reinforced concrete structures more resistant to dynamic loading such as earthquakes. Furthermore, limiting post-event residual damage and deformation allows for immediate re-operation or minimal repairs. These desirable characteristics for structural ‘resilience’, however, present significant challenges due to the brittle nature of concrete, its deformation incompatibility with ductile steel, and the plastic yielding of steel reinforcement. Here, we developed a new composite material system that integrates the unique ductile feature of engineered cementitious composites (ECC) with superelastic shape memory alloy (SMA). In contrast to steel reinforced concrete (RC) and SMA reinforced concrete (SMA-RC), the SMA-ECC beams studied in this research exhibited extraordinary energy dissipation capacity, minimal residual deformation, and full self-recovery of damage under cyclic flexural loading. We found that the tensile strain capacity of ECC, tailored up to 5.5% in this study, allows it to work compatibly with superelastic SMA. Furthermore, the distributed microcracking damage mechanism in ECC is critical for sufficient and reliable recovery of damage upon unloading. This research demonstrates the potential of SMA-ECC for improving resilience of concrete structures under extreme hazard events. (paper)

Numerical tool for SMA material simulation: application to composite structure design

International Nuclear Information System (INIS)

Chemisky, Yves; Tahiri, Vanessa; Duval, Arnaud; Piotrowski, Boris; Ben Zineb, Tarak; Patoor, Etienne

2009-01-01

Composite materials based on shape memory alloys (SMA) have received growing attention over these last few years. In this paper, two particular morphologies of composites are studied. The first one is an SMA/elastomer composite in which a snake-like wire NiTi SMA is embedded into an elastomer ribbon. The second one is a commercial Ni 47 Ti 44 Nb 9 which presents elastic–plastic inclusions in an NiTi SMA matrix. In both cases, the design of such composites required the development of an SMA design tool, based on a macroscopic 3D constitutive law for NiTi alloys. Two different strategies are then applied to compute these composite behaviors. For the SMA/elastomer composite, the macroscopic behavior law is implemented in commercial FEM software, and for the Ni 47 Ti 44 Nb 9 a scale transition approach based on the Mori–Tanaka scheme is developed. In both cases, simulations are compared to experimental data

MODEL EVALUASI INTERNAL KOMPETENSI GURU BAHASA INGGRIS (MODEL_EIKGBI) SMA

OpenAIRE

Sahraini Sahraini; Suwarsih Madya

2015-01-01

Studi ini bertujuan untuk: (1) mengembangkan model evaluasi kompetensi guru bahasa Inggris SMA yang dapat digunakan untuk mengidentifikasi kelebihan dan kekurangan guru dalam proses pemelajaran dan (2) mengetahui efektivitas implementasi evaluasi internal kompetensi guru bahasa Inggris SMA. Studi ini menggunakan metode penelitian dan pengembangan yang dikembangkan oleh Borg & Gall (1983, p.775). Subjek penelitian berjumlah 17 guru yang berasal dari 7 SMA di Sulawesi Selatan. Konstruk instrume...

Fabricating Composite-Material Structures Containing SMA Ribbons

Science.gov (United States)

Turner, Travis L.; Cano, Roberto J.; Lach, Cynthia L.

2003-01-01

An improved method of designing and fabricating laminated composite-material (matrix/fiber) structures containing embedded shape-memory-alloy (SMA) actuators has been devised. Structures made by this method have repeatable, predictable properties, and fabrication processes can readily be automated. Such structures, denoted as shape-memory-alloy hybrid composite (SMAHC) structures, have been investigated for their potential to satisfy requirements to control the shapes or thermoelastic responses of themselves or of other structures into which they might be incorporated, or to control noise and vibrations. Much of the prior work on SMAHC structures has involved the use SMA wires embedded within matrices or within sleeves through parent structures. The disadvantages of using SMA wires as the embedded actuators include (1) complexity of fabrication procedures because of the relatively large numbers of actuators usually needed; (2) sensitivity to actuator/ matrix interface flaws because voids can be of significant size, relative to wires; (3) relatively high rates of breakage of actuators during curing of matrix materials because of sensitivity to stress concentrations at mechanical restraints; and (4) difficulty of achieving desirable overall volume fractions of SMA wires when trying to optimize the integration of the wires by placing them in selected layers only.

KESULITAN PEMECAHAN MASALAH FISIKA PADA SISWA SMA

Directory of Open Access Journals (Sweden)

Rismatul Azizah

2015-12-01

Full Text Available Telah dilakukan penelitian untuk mengidentifikasi kesulitan pemecahan masalah fisika pada siswa SMA. Penelitian ini menggunakan metode survey dengan menyebarkan angket. Responden terdiri dari 120 siswa yang berasal dari 3 sekolah yaitu, SMA Negeri 1 Bangil, SMA Negeri 8 Malang, dan SMA YADIKA Bangil. Dilakukan pula wawancara pada beberapa guru dan siswa. Berdasarkan hasil penyebaran angket, diperoleh 26% siswa mengalami kesulitan pada materi Suhu dan Kalor, 25% Optik, 21% Fluida Statik, 17% Elastisitas dan Hukum Hooke, dan 11% Kinematika. Kesulitan tersebut salah satunya disebabkan pembelajaran bagi siswa yang kurang maksimal dalam bentuk hands on activity. Sebanyak 88% siswa mengatakan bahwa pembelajaran fisika yang sering dialami adalah dengan metode ceramah. Siswa mengalami kesulitan belajar fisika dalam menyelesaikan permasalahan pada soal sebesar 32%, kesulitan memahami konsep dan rumus 26%, kesulitan menggunakan persamaan atau rumus dalam soal 18%, kesulitan menganalisis grafik dan gambar 17%, dan kesulitan menyimpulkan materi yang telah dipelajari 7%. Kesulitan tersebut terlihat ketika siswa memecahkan permasalahan pada soal kinematika serta suhu dan kalor. Diperoleh dari hasil angket, bahwa 76% siswa mengalami kesulitan dalam memecahkan permasalahan pada soal dengan alasan lupa atau tidak paham, sebesar 19% siswa kurang memahami solusi pemecahan masalah pada soal, dan hanya sebesar 5% siswa mampu memecahkan permasalahan pada soal.

The cld mutation: narrowing the critical chromosomal region and selecting candidate genes.

Science.gov (United States)

Péterfy, Miklós; Mao, Hui Z; Doolittle, Mark H

2006-10-01

Combined lipase deficiency (cld) is a recessive, lethal mutation specific to the tw73 haplotype on mouse Chromosome 17. While the cld mutation results in lipase proteins that are inactive, aggregated, and retained in the endoplasmic reticulum (ER), it maps separately from the lipase structural genes. We have narrowed the gene critical region by about 50% using the tw18 haplotype for deletion mapping and a recombinant chromosome used originally to map cld with respect to the phenotypic marker tf. The region now extends from 22 to 25.6 Mbp on the wild-type chromosome, currently containing 149 genes and 50 expressed sequence tags (ESTs). To identify the affected gene, we have selected candidates based on their known role in associated biological processes, cellular components, and molecular functions that best fit with the predicted function of the cld gene. A secondary approach was based on differences in mRNA levels between mutant (cld/cld) and unaffected (+/cld) cells. Using both approaches, we have identified seven functional candidates with an ER localization and/or an involvement in protein maturation and folding that could explain the lipase deficiency, and six expression candidates that exhibit large differences in mRNA levels between mutant and unaffected cells. Significantly, two genes were found to be candidates with regard to both function and expression, thus emerging as the strongest candidates for cld. We discuss the implications of our mapping results and our selection of candidates with respect to other genes, deletions, and mutations occurring in the cld critical region.

Feasibility study of an active soft catheter actuated by SMA wires

Science.gov (United States)

Konh, Bardia; Karimi, Saeed; Miller, Scott

2018-03-01

This study aims to assess the feasibility of using a combination of thin elastomer tubes and SMA wires to develop an active catheter. Cardiac catheters have been widely used in investigational and interventional procedures such as angiography, angioplasty, electro- physiology, and endocardial ablation. The commercial models manually steer inside the patient's body via internally installed pull wires. Active catheters, on the other hand, have the potential to revolutionize surgical procedures because of their computer-controlled and enhanced motion. Shape memory alloys have been used for almost a decade as a trustworthy actuator for biomedical applications. In this work, SMA wires were attached to a small pressurized elastomer tube to realize deflection. The tube was pressurized to maintain a constant stress on the SMA wires. The tip motion via actuation of SMA wires was then measured and reported. The results of this study showed that by adopting an appropriate training process for the SMA wires prior to performing the experiments and adopting an appropriate internal pressure for the elastomer tube, less external loads on SMA wires would be needed for a consistent actuation.

Pemanfaatan Informasi Olahraga di Media Massa Cetak oleh Guru Pendidikan Jasmani dan Kesehatan dalam Pembelajaran Pendidikan Jasmani dan Kesehatan di SMA 5, SMA 6, SMA 11 Semarang

Directory of Open Access Journals (Sweden)

Muhaimin Muhaimin

2011-01-01

Full Text Available Utilization of information in mass media print by master of physical education and health in physical education and health in SMA 5, SMA 6, SMA 11 Semarang. The presence of print media is now a community needs. That's because, the print media presents a variety of information including information of actual politics, culture, economy, crime, entertainment, and sports. Basically, sports information in the print media have educational value and can add insight to a reading of new knowledge. The study produced these findings: (1 third physical education and health teacher at school who becomes the object research have made use of sports information in the print media to support the success of teaching and learning process, (2 the type of information they use to support the success of learning teaching is a form of news, articles about health, (3 form of utilization is appropriate to set clipping and through direct delivery of the material in the field while providing practice in the field. This method is considered more effective because all students can immediately practice, (4 sports information in the print media meets the needs of teachers and physical health education in supporting the learning process.

Faktor Penghambat Operasionalisasi Kunjungan Rumah di SMA Negeri se-Kota Semarang

Directory of Open Access Journals (Sweden)

Juwita Nasruddin

2015-09-01

Full Text Available Penelitian dilaksanakan berdasarkan fenomena di lapangan pada saat penulis melaksanakan Praktik Pengalaman Lapangan (PPL di SMP Negeri 8 Semarang dan observasi awal di SMA Negeri 8 Semarang. Tujuan dari penelitian ini untuk mengetahui apa faktor penghambat operasionalisasi Home Visit di SMA Negeri se-kota Semarang tahun ajaran 2014/2015. Jenis penelitian yang digunakan oleh penulis dalam penelitian ini yaitu jenis penelitian survei. Untuk populasi pada penelitian ini adalah semua guru BK di SMA se-kota Semarang yaitu sejumlah 59 guru BK. Sampel yang digunakan adalah sejumlah populasi yang ada. Sedangkan instrumen yang digunakan dalam penelitian ini merupakan angket. Analisis data yang digunakan dalam penelitian ini adalah deskriptif persentase. Hasil yang ditemukan bahwa faktor penghambat operasionalisasi Home Visit di SMA Negeri se-kota Semarang mengalami hambatan cukup tinggi dengan presentase sebesar 65,03%. Simpulan yang didapatkan adalah Faktor Penghambat Operasionalisasi Kunjungan Rumah (Home visit di SMA Negeri se-kota Semarang adalah kurangnya pemahaman dari guru BK berkaitan dengan Home Visit. Adapun saran yang diberikan kepada guru BK SMA Negeri se-kota Semarang adalah untuk mempelajari hakikat Home Visit dan melaksanakan prosedur operasionalisasi Home Visit dengan baik dan benar dari perencanaan, pelaksanaan, evaluasi, analisis evaluasi, tindak lanjut hingga laporan. The research was conducted based on the phenomenon on the ground when implementing writer Practice Field Experience (PPL in SMPN 8 Semarang and preliminary observations in SMAN 8 Semarang. The purpose of this study to determine what factors inhibiting the operation of the Home Visit at all SMA Negeri in Semarang throughout the academic year 2014/2015. The type research used by the writer in this study is a survey research. The population in this study were all counselors at SMA in Semarang city. There were 59 counselors. The sample used were as many as the population

Superelastic SMA U-shaped dampers with self-centering functions

Science.gov (United States)

Wang, Bin; Zhu, Songye

2018-05-01

As high-performance metallic materials, shape memory alloys (SMAs) have been investigated increasingly by the earthquake engineering community in recent years, because of their remarkable self-centering (SC) and energy-dissipating capabilities. This paper systematically presents an experimental study on a novel superelastic SMA U-shaped damper (SMA-UD) with SC function under cyclic loading. The mechanical properties, including strength, SC ability, and energy-dissipating capability with varying loading amplitudes and strain rates are evaluated. Test results show that excellent and stable flag-shaped hysteresis loops are exhibited in multiple loading cycles. Strain rate has a negligible effect on the cyclic behavior of the SMA-UD within the dynamic frequency range of typical interest in earthquake engineering. Furthermore, a numerical investigation is performed to understand the mechanical behavior of the SMA-UD. The numerical model is calibrated against the experimental results with reasonable accuracy. Then, the stress–strain states with different phase transformations are also discussed.

Confinement of NORMAL- AND HIGH-STRENGTH CONCRETE by Shape Memory Alloy (SMA) Spirals

Science.gov (United States)

Gholampour, A.; Ozbakkaloglu, T.

2018-01-01

This paper presents the results of an experimental study on the axial compressive behaviour of normal- and high-strength concrete (NSC and HSC) confined by shape memory alloy (SMA) spirals. A spiral pitch space of 36 and 20 mm was used for SMA confinement of NSC and HSC columns, respectively. The confining pressure was applied on the concrete cylinders by SMA spirals that were prestrained at 0, 5.5, and 9.5%. The compression test results on the SMA-confined specimens indicate that the prestrain level of SMA significantly affects the axial compressive behaviour of both NSC and HSC. An increase in the level of prestrain leads to an increase in the peak axial stress and corresponding strain of SMA-confined concrete.

Experimental characterization of self-sensing SMA actuators under controlled convective cooling

International Nuclear Information System (INIS)

Lewis, N; York, A; Seelecke, S

2013-01-01

Shape memory alloy (SMA) wires are attractive for actuation systems due to their high energy density, light weight and silent operation. In addition, they feature self-sensing capabilities by relating electrical resistance measurements to strain changes. In real world applications SMAs typically operate in non-ambient air and it is imperative to understand an actuator’s behavior under varying convective cooling conditions, especially for smaller diameter wires, where convective effects are amplified. This paper shows that the multi-functionality of SMA actuators can be further extended by related heating power to convective air speed. It investigates the relationship between the normalized excess power needed and corresponding airspeed under controlled, laminar airflow patterns in a small-scale wind tunnel. For each experiment, airflow through the wind tunnel, strain in the SMA wire, and power supplied to the SMA wire were controlled, while the stress and resistance of the wire were measured. The ability to understand and predict an SMA wire’s behavior under various external airflows will aid in the design and understanding of future SMA actuated structures, such as micro-air vehicles, and shows that SMAs can function as self-sensing actuators and airspeed sensors. (paper)

Computerized detection of multiple sclerosis candidate regions based on a level set method using an artificial neural network

International Nuclear Information System (INIS)

Kuwazuru, Junpei; Magome, Taiki; Arimura, Hidetaka; Yamashita, Yasuo; Oki, Masafumi; Toyofuku, Fukai; Kakeda, Shingo; Yamamoto, Daisuke

2010-01-01

Yamamoto et al. developed the system for computer-aided detection of multiple sclerosis (MS) candidate regions. In a level set method in their proposed method, they employed the constant threshold value for the edge indicator function related to a speed function of the level set method. However, it would be appropriate to adjust the threshold value to each MS candidate region, because the edge magnitudes in MS candidates differ from each other. Our purpose of this study was to develop a computerized detection of MS candidate regions in MR images based on a level set method using an artificial neural network (ANN). To adjust the threshold value for the edge indicator function in the level set method to each true positive (TP) and false positive (FP) region, we constructed the ANN. The ANN could provide the suitable threshold value for each candidate region in the proposed level set method so that TP regions can be segmented and FP regions can be removed. Our proposed method detected MS regions at a sensitivity of 82.1% with 0.204 FPs per slice and similarity index of MS candidate regions was 0.717 on average. (author)

SMA Foils for MEMS: From Material Properties to the Engineering of Microdevices

Science.gov (United States)

Kohl, Manfred; Ossmer, Hinnerk; Gueltig, Marcel; Megnin, Christof

2018-03-01

In the early nineties, microelectromechanical systems (MEMS) technology has been still in its infancy. As silicon (Si) is not a transducer material, it was clear at the very beginning that mechanically active materials had to be introduced to MEMS in order to enable functional microdevices with actuation capability beyond electrostatics. At that time, shape memory alloys (SMAs) have been available in bulk form, mainly as SMA wires and SMA plates. On the macro scale, these materials show highest work densities compared to other actuation principles in the order of 107 J/m3, which stimulated research on the integration of SMA to MEMS. Subsequently, two approaches for producing planar materials have been initiated (1) magnetron sputtering of SMA thin films and (2) the integration of rolled SMA foils, which both turned out to be very successful creating a paradigm change in microactuation technology. The following review covers important milestones of the research and development of SMA foil-based microactuators including materials characterization, design engineering, technology, and demonstrator development as well as first commercial products.

SMA Foils for MEMS: From Material Properties to the Engineering of Microdevices

Science.gov (United States)

Kohl, Manfred; Ossmer, Hinnerk; Gueltig, Marcel; Megnin, Christof

2017-12-01

In the early nineties, microelectromechanical systems (MEMS) technology has been still in its infancy. As silicon (Si) is not a transducer material, it was clear at the very beginning that mechanically active materials had to be introduced to MEMS in order to enable functional microdevices with actuation capability beyond electrostatics. At that time, shape memory alloys (SMAs) have been available in bulk form, mainly as SMA wires and SMA plates. On the macro scale, these materials show highest work densities compared to other actuation principles in the order of 107 J/m3, which stimulated research on the integration of SMA to MEMS. Subsequently, two approaches for producing planar materials have been initiated (1) magnetron sputtering of SMA thin films and (2) the integration of rolled SMA foils, which both turned out to be very successful creating a paradigm change in microactuation technology. The following review covers important milestones of the research and development of SMA foil-based microactuators including materials characterization, design engineering, technology, and demonstrator development as well as first commercial products.

Investigations on Vibration Characteristics of Sma Embedded Horizontal Axis Wind Turbine Blade

Science.gov (United States)

Jagadeesh, V.; Yuvaraja, M.; Chandhru, A.; Viswanathan, P.; Senthil kumar, M.

2018-02-01

Vibration induced in wind turbine blade is a solemn problem as it reduces the life of the blade and also it can create critical vibration onto the tower, which may cause serious damage to the tower. The aim of this paper is to investigate the vibration characteristics of the prototype horizontal axis wind turbine blade. Shape memory alloys (SMA), with its variable physical properties, provides an alternative actuating mechanism. Heating an SMA causes a change in the elastic modulus of the material and hence SMAs are used as a damping material. A prototype blade with S1223 profile has been manufactured and the natural frequency is found. The natural frequency is found by incorporating the single SMA wire of 0.5mm diameter over the surface of the blade for a length of 240 mm. Similarly, number of SMA wires over the blade is increased up to 3 and the natural frequency is found. Frequency responses showed that the embedment of SMA over the blade’s surface will increase the natural frequency and reduce the amplitude of vibration. This is because of super elastic nature of SMA. In this paper, when SMA wire of 0.5 mm diameter and of length of 720 mm is embedded on the blade, an increase in the natural frequency by 6.3% and reducing the amplitude by 64.8%. Results of the experimental modal and harmonic indicates the effectiveness of SMA as a passive vibration absorber and that it has potential as a modest and high-performance method for controlling vibration of the blade.

SMA bellows as reversible thermal sensors/actuators

International Nuclear Information System (INIS)

Damanpack, A R; Bodaghi, M; Liao, W H

2015-01-01

In this paper, the feasibility of reversible bellows made of shape memory alloys (SMAs) in sensory and actuated applications to transfer pressure and/or temperature into a linear motion is investigated. An analytical three-dimensional model is developed to simulate key features of SMAs including martensitic transformation, reorientation of martensite variants, the shape memory effect, and pseudo-elasticity. Axisymmetric two-dimensional theory of thermo-inelasticity based on the non-linear Green–Lagrange strain tensor is employed to derive the equilibrium equations. A finite element method along with an iterative incremental elastic-predictor–inelastic-corrector procedure is developed to solve the governing equations with both material and geometrical non-linearities. The feasibility of reversible SMA bellows in transferring pressure and/or temperature into a linear motion is numerically demonstrated. In this respect, the effects of geometric parameters, magnitude of thermo-mechanical loadings and end conditions on the performances of SMA bellows are evaluated and discussed in depth. This study provides pertinent results toward an efficient and reliable design of reversible thermally-driven SMA bellows. (paper)

Persepsi Siswa Terhadap Pembelajaran Guru Pendidikan Jasmani Di SMA Muhammadiyah Kediri

Directory of Open Access Journals (Sweden)

Hendra Mashuri

2017-05-01

Full Text Available Tujuan yang ingin dicapai dalam penelitian ini adalah untuk memperoleh informasi tentang persepsi siswa terhadap pembelajaran guru pendidikan jasmani di SMA Muhammadiyah Kediri. Rumusan masalah dalam penelitian ini adalah bagaimana persepsi siswa terhadap pembelajaran guru pendidikan jasmani di SMA Muhammadiyah Kediri? Jenis penelitian ini adalah penelitian survei. Populasi yang digunakan adalah seluruh siswa SMA Muhammadiyah Kediri, sampel yang diambil berjumlah 60 siswa yang terdiri dari 20 siswa dari masing-masing kelas. Instrumen yang digunakan adalah angket dan dokumentasi. Teknik analisis data menggunakan persentase. Hasil penelitian menunjukkan bahwa persepsi siswa terhadap proses pembelajaran SMA Muhammadiyah Kediri mendapatkan skor 3115 atau rata-rata jawaban siswa 51,917 dengan persentase sebesar 74% dan masuk dalam kategori “Baik”. Dengan demikian dapat dikatakan bahwa persepsi siswa terhadap pembelajaran guru pendidikan jasmani adalah baik.

Sistem Informasi Akademik pada SMA Swasta Hang Tuah Belawan

OpenAIRE

Syarifuddin, Ruisya

2015-01-01

Perancangan Sistem Informasi Akademik pada SMA Swasta Hang Tuah Belawan ini bertujuan untuk mempermudah proses pencarian atau searching data dan informasi untuk seluruh Siswa SMA Swasta Hang Tuah Belawan yang mengalami kesulitan dalam memperoleh data mengenai masalah Akademik tersebut. Faasilitas yang terdapat dalam aplikasi ini berupa penyediaan data dan informasi mengenai beritaberita terbaru, profil agenda kegiatan, dan data-data yang berguna untuk kelangsungan belajar si...

Manajemen kelas dalam pembelajaran matematika di SMA Negeri Yogyakarta

OpenAIRE

Nisak Ruwah Ibnatur Husnul; Heri Retnawati

2017-01-01

Penelitian ini bertujuan untuk mengetahui manajemen kelas yang berupa perencanaan, pengorganisasian, penggerakan/kepemimpinan dan pengevaluasian dari pembelajaran matematika yang dilakukan oleh guru matematika di SMA Negeri Yogyakarta. Dengan menggunakan penelitian kualitatif jenis studi kasus ini dilakukan di SMA Negeri 5, 8 dan 9 Yogyakarta dengan subjek data adalah kepala sekolah, guru kurikulum, guru matematika dan siswa. Untuk teknik pengumpulan datanya dengan pedoman observasi dan pedom...

PreSMA stimulation changes task-free functional connectivity in the fronto-basal-ganglia that correlates with response inhibition efficiency.

Science.gov (United States)

Xu, Benjamin; Sandrini, Marco; Wang, Wen-Tung; Smith, Jason F; Sarlls, Joelle E; Awosika, Oluwole; Butman, John A; Horwitz, Barry; Cohen, Leonardo G

2016-09-01

Previous work using transcranial magnetic stimulation (TMS) demonstrated that the right presupplementary motor area (preSMA), a node in the fronto-basal-ganglia network, is critical for response inhibition. However, TMS influences interconnected regions, raising the possibility of a link between the preSMA activity and the functional connectivity within the network. To understand this relationship, we applied single-pulse TMS to the right preSMA during functional magnetic resonance imaging when the subjects were at rest to examine changes in neural activity and functional connectivity within the network in relation to the efficiency of response inhibition evaluated with a stop-signal task. The results showed that preSMA-TMS increased activation in the right inferior-frontal cortex (rIFC) and basal ganglia and modulated their task-free functional connectivity. Both the TMS-induced changes in the basal-ganglia activation and the functional connectivity between rIFC and left striatum, and of the overall network correlated with the efficiency of response inhibition and with the white-matter microstructure along the preSMA-rIFC pathway. These results suggest that the task-free functional and structural connectivity between the rIFCop and basal ganglia are critical to the efficiency of response inhibition. Hum Brain Mapp 37:3236-3249, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Optimal design of damping layers in SMA/GFRP laminated hybrid composites

Science.gov (United States)

Haghdoust, P.; Cinquemani, S.; Lo Conte, A.; Lecis, N.

2017-10-01

This work describes the optimization of the shape profiles for shape memory alloys (SMA) sheets in hybrid layered composite structures, i.e. slender beams or thinner plates, designed for the passive attenuation of flexural vibrations. The paper starts with the description of the material and architecture of the investigated hybrid layered composite. An analytical method, for evaluating the energy dissipation inside a vibrating cantilever beam is developed. The analytical solution is then followed by a shape profile optimization of the inserts, using a genetic algorithm to minimize the SMA material layer usage, while maintaining target level of structural damping. Delamination problem at SMA/glass fiber reinforced polymer interface is discussed. At the end, the proposed methodology has been applied to study the hybridization of a wind turbine layered structure blade with SMA material, in order to increase its passive damping.

Behavior of NiTiNb SMA wires under recovery stress or prestressing.

Science.gov (United States)

Choi, Eunsoo; Nam, Tae-Hyun; Chung, Young-Soo; Kim, Yeon-Wook; Lee, Seung-Yong

2012-01-05

The recovery stress of martensitic shape-memory alloy [SMA] wires can be used to confine concrete, and the confining effectiveness of the SMA wires was previously proved through experimental tests. However, the behavior of SMA wires under recovery stress has not been seriously investigated. Thus, this study conducted a series of tests of NiTiNb martensitic SMA wires under recovery stress with varying degrees of prestrain on the wires and compared the behavior under recovery stress with that under prestressing of the wires. The remaining stress was reduced by the procedure of additional strain loading and unloading. More additional strains reduced more remaining stresses. When the SMA wires were heated up to the transformation temperature under prestress, the stress on the wires increased due to the state transformation. Furthermore, the stress decreased with a decreasing temperature of the wires down to room temperature. The stress of the NiTiNb wires was higher than the prestress, and the developed stress seemed to depend on the composition of the SMAs. When an additional strain was subsequently loaded and unloaded on the prestressed SMA wires, the remaining stress decreased. Finally, the remaining stress becomes zero when loading and unloading a specific large strain.

PERANGKAT PENGEMBANGAN DIRI UNTUK MENINGKATKAN KOMPETENSI GURU DAN PENGEMBANGAN KEPRIBADIAN SISWA SMA

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Wenny Hulukati

2014-06-01

Abstrak: Perangkat Pengembangan Diri untuk Meningkatkan Kompetensi Guru dan Pengembangan Kepribadian Siswa SMA. Penelitian ini bertujuan mengembangkan perangkat pengembangan diri untuk meningkatkan kompetensi guru dan pengembangan kepribadian siswa SMA. Kegiatan penelitian ini diawali dengan studi pendahuluan yang berkaitan dengan kompentensi guru pembimbing dalam melaksanakan pelayanan bimbingan dan konseling dan kecenderungan kepribadian siswa SMA. Langkah berikutnya adalah mendesain dan mengembangkan draf, dan diakhiri dengan kegiatan uji keefektifan produk. Dari kegiatan penelitian pengembangan ini telah dihasilkan produk pengembangan yang valid dan handal yang meliputi panduan guru, panduan siswa, dan panduan penilaian. Berdasarkan hasil uji keefektifan terhadap produk pengembangan diperoleh informasi bahwa perangkat panduan pengembangan diri efektif diguna­kan untuk meningkatkan kompetensi guru pembimbing dalam melaksanakan pelayanan bimbingan dan konseling dan pengembangan kepribadian siswa SMA.

Monotonic and cyclic bond behavior of confined concrete using NiTiNb SMA wires

International Nuclear Information System (INIS)

Choi, Eunsoo; Chung, Young-Soo; Kim, Yeon-Wook; Kim, Joo-Woo

2011-01-01

This study conducts bond tests of reinforced concrete confined by shape memory alloy (SMA) wires which provide active and passive confinement of concrete. This study uses NiTiNb SMA which usually shows wide temperature hysteresis; this is a good advantage for the application of shape memory effects. The aims of this study are to investigate the behavior of SMA wire under residual stress and the performance of SMA wire jackets in improving bond behavior through monotonic-loading tests. This study also conducts cyclic bond tests and analyzes cyclic bond behavior. The use of SMA wire jackets transfers the bond failure from splitting to pull-out mode and satisfactorily increases bond strength and ductile behavior. The active confinement provided by the SMA plays a major role in providing external pressure on the concrete because the developed passive confinement is much smaller than the active confinement. For cyclic behavior, slip and circumferential strain are recovered more with larger bond stress. This recovery of slip and circumferential strain are mainly due to the external pressure of the SMA wires since cracked concrete cannot provide any elastic recovery

Contribution of the pre-SMA to the production of words and non-speech oral motor gestures, as revealed by repetitive transcranial magnetic stimulation (rTMS).

Science.gov (United States)

Tremblay, Pascale; Gracco, Vincent L

2009-05-01

An emerging theoretical perspective, largely based on neuroimaging studies, suggests that the pre-SMA is involved in planning cognitive aspects of motor behavior and language, such as linguistic and non-linguistic response selection. Neuroimaging studies, however, cannot indicate whether a brain region is equally important to all tasks in which it is activated. In the present study, we tested the hypothesis that the pre-SMA is an important component of response selection, using an interference technique. High frequency repetitive TMS (10 Hz) was used to interfere with the functioning of the pre-SMA during tasks requiring selection of words and oral gestures under different selection modes (forced, volitional) and attention levels (high attention, low attention). Results show that TMS applied to the pre-SMA interferes selectively with the volitional selection condition, resulting in longer RTs. The low- and high-attention forced selection conditions were unaffected by TMS, demonstrating that the pre-SMA is sensitive to selection mode but not attentional demands. TMS similarly affected the volitional selection of words and oral gestures, reflecting the response-independent nature of the pre-SMA contribution to response selection. The implications of these results are discussed.

Miskonsepsi Buku Ajar Fisika SMA Kelas X Pada Pokok Bahasan Dinamika Gerak

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Fachmi Nurdiansyah

2018-03-01

Full Text Available Penelitian ini bertujuan untuk memaparkan bentuk-bentuk miskonsepsi pada pokok bahasan dinamika gerak dalam buku ajar fisika SMA kelas X. Adapun buku ajar yang digunakan dalam penelitian ini, yaitu: (1 Fisika untuk SMA/MA Kelas X Semester I karangan RA dan SI yang diterbitkan tahun 2012 oleh penerbit IP, (2 Fisika untuk SMA/MA Kelas X Semester I karangan TPM yang diterbitkan tahun 2013 oleh penerbit VP, dan (3 Fisika Peminatan untuk SMA/MA Kelas X karangan SN dan SZ yang diterbitkan tahun 2013 oleh penerbit YW. Penelitian ini merupakan penelitian kualitatif deskriptif. Objek dalam penelitian ini adalah data berupa aspek penjelasan konsep, penulisan rumus, penulisan simbol, penulisan satuan, dan penyajian gambar pada pokok bahasan dinamika gerak dalam buku ajar fisika SMA. Penelitian dilakukan dengan cara menganalisis data dalam buku ajar fisika SMA yang dibandingkan dengan buku teks fisika universitas. Berdasarkan analisis data yang telah dilakukan, dapat disimpulkan bahwa miskonsepsi pada pokok bahasan dinamika gerak terdapat dalam buku ajar fisika SMA. Buku ajar IP mengalami miskonsepsi pada aspek penjelasan konsep dengan persentase 10%, penulisan rumus dengan persentase 57,14%, penulisan simbol dengan persentase 46,15%, dan penyajian gambar dengan persentase 20%. Buku ajar VP mengalami miskonsepsi pada aspek penjelasan konsep dengan persentase 10%, penulisan rumus dengan persentase 85,71%, penulisan simbol dengan persentase 79,62%, dan penyajian gambar dengan persentase 80%. Buku ajar YW mengalami miskonsepsi pada aspek penjelasan konsep dengan persentase 10%, penulisan rumus dengan persentase 85,71%, penulisan simbol dengan persentase 69,23, dan penyajian gambar dengan persentase 20%. Pada aspek penulisan satuan, tidak terdapat miskonsepsi dalam buku ajar IP, VP, dan YW.

Fatigue crack behavior on a Cu-Zn-Al SMA

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V. Di Cocco

2014-10-01

Full Text Available In recent years, mechanical property of many SMA has improved in order to introduce these alloys in specific field of industry. Main examples of these alloys are the NiTi, Cu-Zn-Al and Cu-Al-Ni which are used in many fields of engineering such as aerospace or mechanical systems. Cu-Zn-Al alloys are characterized by good shape memory properties due to a bcc disordered structure stable at high temperature called β-phase, which is able to change by means of a reversible transition to a B2 structure after appropriate cooling, and reversible transition from B2 secondary to DO3 order, under other types of cooling. In β-Cu-Zn-Al shape memory alloys, the martensitic transformation is not in equilibrium at room temperature. It is therefore often necessary to obtain the martensitic structure, using a thermal treatment at high temperature followed by quenching. The martensitic phases can be either thermally-induced spontaneous transformation, or stressinduced, or cooling, or stressing the β- phase. Direct quenching from high temperatures to the martensite phase is the most effective because of the non-diffusive character of the transformation. The martensite inherits the atomic order from the β-phase. Precipitation of many kinds of intermetallic phases is the main problem of treatment on cu-based shape memory alloy. For instance, a precipitation of α-phase occurs in many low aluminum copper based SMA alloy and presence of α-phase implies a strong degradation of shape recovery. However, Cu-Zn-Al SMA alloys characterized by aluminum contents less than 5% cover a good cold machining and cost is lower than traditional NiTi SMA alloys. In order to improve the SMA performance, it is always necessary to identify the microstructural changing in mechanical and thermal conditions, using X-Ray analyses. In this work a Cu-Zn-Al SMA alloy obtained in laboratory has been microstructurally and metallographically characterized by means of X-Ray diffraction and Light

Crack-closing of cement mortar beams using NiTi cold-drawn SMA short fibers

Science.gov (United States)

Choi, Eunsoo; Kim, Dong Joo; Chung, Young-Soo; Kim, Hee Sun; Jung, Chungsung

2015-01-01

In this study, crack-closing tests of mortar beams reinforced by shape memory alloy (SMA) short fibers were performed. For this purpose, NiTi SMA fibers with a diameter of 0.965 mm and a length of 30 mm were made from SMA wires of 1.0 mm diameter by cold drawing. Four types of SMA fibers were prepared, namely, straight and dog-bone-shaped fiber and the two types of fibers with paper wrapping in the middle of the fibers. The paper provides an unbonded length of 15 mm. For bending tests, six types of mortar beams with the dimensions of 40 mm × 40 mm × 160 mm (B×H×L) were prepared. The SMA fibers were placed at the bottom center of the beams along with an artificial crack of 10 mm depth and 1 mm thickness. This study investigated the influence of SMA fibers on the flexural strength of the beams from the measured force- deflection curves. After cracking, the beams were heated at the bottom by fire to activate the SMA fibers. Then, the beams recovered the deflection, and the cracks were closed. This study evaluated crack-closing capacity using the degree of crack recovery and deflection-recovery factor. The first factor is estimated from the crack-width before and after crack-closing, and the second one is obtained from the downward deflection due to loading and the upward deflection due to the closing force of the SMA fibers.

PENGEMBANGAN MODEL PEMBELAJARAN KIMIA UNTUK MENINGKATKAN KETERAMPILAN PROSES DAN KETERAMPILAN BERPIKIR SISWA SMA

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Siti Darsati

2015-01-01

Full Text Available Tujuan penyusunan model pembelajaran kimia ini untuk meningkatkan keterampilan proses dan keterampilan berpikir siswa SMA. Model Pembelajaran Laju Reaksi untuk SMA mengandung 17 konsep, meliputi konsep abstrak, konsep yang berdasarkan prinsip dan konsep yang menyatakan simbol. Keterampilan Berpikir Kritis dan Keterampilan Proses Sains yang dikembangkan lebih banyak pada keterampilan menyimpulkan. Model ini telah di implementasikan pada 2 SMA di Kodya/Kabupaten Bandung. Kata kunci: Model pembelajaran, keterampilan proses, keterampilan berpikir

Acquisition through Horizontal Gene Transfer of Plasmid pSMA198 by Streptococcus macedonicus ACA-DC 198 Points towards the Dairy Origin of the Species

Science.gov (United States)

Papadimitriou, Konstantinos; Anastasiou, Rania; Maistrou, Eleni; Plakas, Thomas; Papandreou, Nikos C.; Hamodrakas, Stavros J.; Ferreira, Stéphanie; Supply, Philip; Renault, Pierre; Pot, Bruno; Tsakalidou, Effie

2015-01-01

Background Streptococcus macedonicus is an intriguing streptococcal species whose most frequent source of isolation is fermented foods similarly to Streptococcus thermophilus. However, S. macedonicus is closely related to commensal opportunistic pathogens of the Streptococcus bovis/Streptococcus equinus complex. Methodology/Principal Findings We analyzed the pSMA198 plasmid isolated from the dairy strain Streptococcus macedonicus ACA-DC 198 in order to provide novel clues about the main ecological niche of this bacterium. pSMA198 belongs to the narrow host range pCI305/pWV02 family found primarily in lactococci and to the best of our knowledge it is the first such plasmid to be reported in streptococci. Comparative analysis of the pSMA198 sequence revealed a high degree of similarity with plasmids isolated from Lactococcus lactis strains deriving from milk or its products. Phylogenetic analysis of the pSMA198 Rep showed that the vast majority of closely related proteins derive from lactococcal dairy isolates. Additionally, cloning of the pSMA198 ori in L. lactis revealed a 100% stability of replication over 100 generations. Both pSMA198 and the chromosome of S. macedonicus exhibit a high percentage of potential pseudogenes, indicating that they have co-evolved under the same gene decay processes. We identified chromosomal regions in S. macedonicus that may have originated from pSMA198, also supporting a long co-existence of the two replicons. pSMA198 was also found in divergent biotypes of S. macedonicus and in strains isolated from dispersed geographic locations (e.g. Greece and Switzerland) showing that pSMA198’s acquisition is not a recent event. Conclusions/Significance Here we propose that S. macedonicus acquired plasmid pSMA198 from L. lactis via an ancestral genetic exchange event that took place most probably in milk or dairy products. We provide important evidence that point towards the dairy origin of this species. PMID:25584532

PENGEMBANGAN PERANGKAT PEMBELAJARAN KOMPETENSI SULIT MATEMATIKA SMA DI RIAU

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Ummi Aisyah

2014-05-01

Full Text Available Tujuan penelitian ini adalah untuk menghasilkan perangkat pembelajaran kompetensi sulit matematika SMA di Provinsi Riau yang berkualitas baik/layak yaitu valid, praktis, dan efektif. Penelitian ini merupakan penelitian pengembangan yang mengembangkan perangkat pembelajaran kompetensi sulit matematika SMA dengan menggunakan model pengembangan 4-D yang dikembangkan oleh Thiagarajan, Semmel & Semmel yang telah dimodifikasi sehingga hanya memuat tahap pen-definisian, perancangan, dan pengembangan. Penelitian ini menghasilkan perangkat pembelajaran kompetensi sulit matematika SMA yang meliputi silabus, rencana pelaksanaan pembelajaran (RPP, lembar kegiatan siswa (LKS, dan instrumen tes. Hasil validasi menunjukkan bahwa silabus, RPP, LKS yang dikembangkan memiliki kategori sangat valid untuk masing-masing silabus, RPP, LKS, dan test instrument. Hasil uji coba lapangan menunjukkan bahwa perangkat yang dikembangkan praktis dan efektif. Kepraktisan mencapai hasil sangat baik ditinjau dari penilaian guru dan siswa. Keefektifan ditinjau dari ketuntasan belajar siswa dan hasil observasi keterlaksanaan pembelajaran. Secara klasikal ketuntasan belajar mencapai 84,38%. Secara keseluruhan, hasil penelitian menunjukkan bahwa perangkat pembelajaran yang dikembangkan adalah layak untuk digunakan. Kata Kunci: pengembangan, perangkat pembelajaran, kompetensi sulit matematika

PEMBELAJARAN THINK-PAIR-SHARE, KETERAMPILAN METAKOGNITIF, DAN HASIL BELAJAR KOGNITIF SISWA SMA

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Sri Amnah S.

2012-05-01

Full Text Available Abstract: Think-Pair-Share Learning, Meta-cognitive Skills and Cognitive Learning Outcomes. The study investigates the effects of meta-cognitive skills based Think-Pair-Share cooperative learning on meta-cognitive skills and cognitive learning outcomes of 11th grade students of Senior High Schools in Pekanbaru. The sample consists of 11th grade students of SMA 9 as an experiment group and 11th grade students SMA 10 as a control group. Based on analyzing the data using ANCOVA, the results show that there is a signifi­cant difference in meta-cognitive skills and cognitive learning outcomes of the students in the experimental and the control groups, and there is no significant difference between students who have high and low academic levels in their meta-cognitive skills and cognitive learning outcomes. Abstrak: Pembelajaran Think-Pair-Share, Keterampilan Metakognitif, dan Hasil Belajar Kognitif Siswa SMA. Penelitian ini bertujuan mengukur pengaruh pembela­jaran koperatif Think-Pair-Share terha­dap keterampilan metakognitif dan hasil belajar kognitif siswa SMA. Sampel dipilih secara acak dari popu­lasi 13 SMA di Pekanbaru. Dengan menggunakan ANAKOVA, hasilnya menunjukkan bahwa terdapat per­bedaan yang nyata keterampilan metakognitif dan hasil belajar kognitif siswa di kelompok eksperimental dan kelompok control, dan tidak ada perbedaan yang nyata antara siswa berkemampuan akademik tinggi dan akademik rendah pada keterampilan metakognitif dan hasil belajar kognitifnya.

Full-scale flight tests of aircraft morphing structures using SMA actuators

Science.gov (United States)

Mabe, James H.; Calkins, Frederick T.; Ruggeri, Robert T.

2007-04-01

In August of 2005 The Boeing Company conducted a full-scale flight test utilizing Shape Memory Alloy (SMA) actuators to morph an engine's fan exhaust to correlate exhaust geometry with jet noise reduction. The test was conducted on a 777-300ER with GE-115B engines. The presence of chevrons, serrated aerodynamic surfaces mounted at the trailing edge of the thrust reverser, have been shown to greatly reduce jet noise by encouraging advantageous mixing of the free, and fan streams. The morphing, or Variable Geometry Chevrons (VGC), utilized compact, light weight, and robust SMA actuators to morph the chevron shape to optimize the noise reduction or meet acoustic test objectives. The VGC system was designed for two modes of operation. The entirely autonomous operation utilized changes in the ambient temperature from take-off to cruise to activate the chevron shape change. It required no internal heaters, wiring, control system, or sensing. By design this provided one tip immersion at the warmer take-off temperatures to reduce community noise and another during the cooler cruise state for more efficient engine operation, i.e. reduced specific fuel consumption. For the flight tests a powered mode was added where internal heaters were used to individually control the VGC temperatures. This enabled us to vary the immersions and test a variety of chevron configurations. The flight test demonstrated the value of SMA actuators to solve a real world aerospace problem, validated that the technology could be safely integrated into the airplane's structure and flight system, and represented a large step forward in the realization of SMA actuators for production applications. In this paper the authors describe the development of the actuator system, the steps required to integrate the morphing structure into the thrust reverser, and the analysis and testing that was required to gain approval for flight. Issues related to material strength, thermal environment, vibration

SMA spring-based artificial muscle actuated by hot and cool water using faucet-like valve

Science.gov (United States)

Park, Cheol Hoon; Son, Young Su

2017-04-01

An artificial muscle for a human arm-like manipulator with high strain and high power density are under development, and an SMA(Shape memory alloy) spring is a good actuator for this application. In this study, an artificial muscle composed of a silicon tube and a bundle of SMA(Shape memory alloy) springs is evaluated. A bundle of SMA springs consists of five SMA springs which are fabricated by using SMA wires with a diameter of 0.5 mm, and hot and cool water actuates it by heating and cooling SMA springs. A faucet-like valve was also developed to mix hot water and cool water and control the water temperature. The mass of silicon tube and a bundle of SMA springs is only 3.3 g and 2.25 g, respectively, and the total mass of artificial muscle is 5.55 g. It showed good actuating performance for a load with a mass of 2.3 kg and the power density was more than 800 W/kg for continuous valve switching with a cycle of 0.6 s. The faucet-like valve can switch a water output from hot water to cold water within 0.3s, and the artificial muscle is actuated well in response to the valve position and speed. It is also presented that the temperature of the mixed water can be controlled depending on the valve position, and the displacement of the artificial muscle can be controlled well by the mixed water. Based on these results, SMA spring-based artificial muscle actuated by hot and cool water could be applicable to the human arm-like robot manipulators.

PENERAPAN TEKNOLOGI WEB SEKOLAH BAGI SMP DAN SMA MUHAMMADIYAH KARTASURA

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Heru Supriyono

2016-03-01

Full Text Available Observation and interview with headmasters, teachers and administrative employees results showed that one of main problems faced by SMP Muhammadiyah 1 Kartasura and SMA Muhammadiyah 4 Kartasura is the do not have a representative school website. Based on this observation, after making discussion with headmasters, the community services team proposed an implementation of school website and train one of chosen teacher to manage implemented website. The outcomes of the community service activities are involving a school website for SMP Muhammadiyah 1 Kartasura and SMA Muhammadiyah 4 Kartasura and scientific publication draft. The contribution of each school is including providing information which will be uploaded to the website, providing fee for domain and hosting cost, and providing facilities for administrator training. The duration of this commuity services is three months. The results of the community services is both SMP Muhammadiyah 1 Kartasura dan SMA Muhammadiyah 4 Kartasura are now have representative website for their promotion and administative activities.

PENGEMBANGAN KINERJA GURU MELALUI PENELITIAN TINDAKAN KELAS PADA SMA NEGERI DI KOTA PALOPO

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Hilal Muhammad

2015-12-01

Tujuan penelitian ini adalah untuk mengungkap: (1 pelaksanaan pengembangan kinerja guru melalui PTK pada SMA Negeri di Kota Palopo; dan (2 hambatan da-lam pelaksanaan pengembangan kinerja guru melalui PTK pada SMA Negeri di Kota Palopo. Jenis penelitian adalah penelitian lapangan yang kajiannya bersifat kualitatif-verifikatif. Pendekatan yang digunakan adalah pendekatan fenomeno-logi. Metode pengumpulan data yang digunakan dalam penelitian ini adalah wawancara, observasi, dan dokumentasi. Hasil penelitian ini menunjukkan dua hal. Pertama, pengembangan kinerja guru melalui PTK pada SMA Negeri di Kota Palopo belum berjalan optimal dan baru sebatas memenuhi kebutuhan persyarat-an kenaikan pangkat. Potensi guru belum dimanfaatkan melalui pemberdayaan, khususnya penelitian tindakan kelas. Kedua, hambatan dalam pelaksanaan pe-ngembangan kinerja guru melalui PTK pada SMA Negeri di Kota Palopo adalah keterbatasan waktu, dana, sumber referensi kurang, lingkungan tidak kondusif, dan motivasi kurang. Selain itu, sebagian guru juga masih mengalami kesulitan dalam melakukan dan menyusun laporan hasil PTK.

Constitutive modeling of SMA SMP multifunctional high performance smart adaptive shape memory composite

International Nuclear Information System (INIS)

Jarali, Chetan S; Raja, S; Upadhya, A R

2010-01-01

Materials design involving the thermomechanical constitutive modeling of shape memory alloy (SMA) and shape memory polymer (SMP) composites is a key topic in the development of smart adaptive shape memory composites (SASMC). In this work, a constitutive model for SASMC is developed. First, a one-dimensional SMA model, which can simulate the pseudoelastic (PE) and shape memory effects (SME) is presented. Subsequently, a one-dimensional SMP model able to reproduce the SME is addressed. Both SMA and SMP models are based on a single internal state variable, namely the martensite fraction and the frozen fraction, which can be expressed as a function of temperature. A consistent form of the analytical solution for the SMP model is obtained using the fourth-order Runge–Kutta method. Finally, the SASMC constitutive model is proposed, following two analytical homogenization approaches. One approach is based on an equivalent inclusion method and the other approach is the rule of mixtures. The SMA and SMP constitutive models are validated independently with experimental results. However, the validation of the composite model is performed using the two homogenization approaches and a close agreement in results is observed. Results regarding the isothermal and thermomechanical stress–strain responses are analyzed as a function of SMA volume fraction. Further, it is concluded that the proposed composite model is able to reproduce consistently the overall composite response by taking into consideration not only the phase transformations, variable modulus and transformation stresses in SMA but also the variable modulus, the evolution of stored strain and thermal strain in the SMP

Fabrication and characterization of a dual-joint smart inhaler nozzle actuated by embedded SMA wires

International Nuclear Information System (INIS)

Furst, Stephen J; Seelecke, Stefan

2014-01-01

Shape memory alloy (SMA) wires offer a novel solution for many embedded actuator and sensor applications. Small SMA wires in particular can be heated with a relatively low electric current, cool rapidly, and serve as a sensor thanks to a measurable resistance change. However, the challenges of fabrication with SMA actuator wires as well as their hysteretic nature have prevented them from finding mainstream application. This work focuses on the process used to control the fabrication of an SMA-actuated adaptive nozzle for the previously presented Smart Inhaler application. The elements of nozzle design that facilitate fabrication are summarized and an assembly setup and procedure is presented for controlling the stress and strain in the SMA wires while they are attached to the nozzle structure via temperature-resistant adhesives. Finally, the performance of the nozzle is characterized by measuring the changes in nozzle deflection and SMA wire strain and resistance in response to a controlled Joule heating power input. Results show controlling pre-stress in the wires during assembly can lead to reproducible behavior, an input heating power serves to control nozzle deflection, and a measured resistance can provide a useful sensor of SMA wire strain and nozzle joint deflection. (paper)

YOUNG STELLAR POPULATIONS IN MYStIX STAR-FORMING REGIONS: CANDIDATE PROTOSTARS

Energy Technology Data Exchange (ETDEWEB)

Romine, Gregory; Feigelson, Eric D.; Getman, Konstantin V. [Department of Astronomy and Astrophysics, Pennsylvania State University, 525 Davey Lab, University Park, PA 16802 (United States); Kuhn, Michael A. [Millennium Institute of Astrophysics, Camino El Observatorio 1515, Las Condes, Santiago (Chile); Povich, Matthew S., E-mail: edf@astro.psu.edu [Department of Physics and Astronomy, California State Polytechnic University, 3801 West Temple Ave., Pomona, CA 91768 (United States)

2016-12-20

The Massive Young Star-Forming Complex in Infrared and X-ray (MYStIX) project provides a new census on stellar members of massive star-forming regions within 4 kpc. Here the MYStIX Infrared Excess catalog and Chandra -based X-ray photometric catalogs are mined to obtain high-quality samples of Class I protostars using criteria designed to reduce extragalactic and Galactic field star contamination. A total of 1109 MYStIX Candidate Protostars (MCPs) are found in 14 star-forming regions. Most are selected from protoplanetary disk infrared excess emission, but 20% are found from their ultrahard X-ray spectra from heavily absorbed magnetospheric flare emission. Two-thirds of the MCP sample is newly reported here. The resulting samples are strongly spatially associated with molecular cores and filaments on Herschel far-infrared maps. This spatial agreement and other evidence indicate that the MCP sample has high reliability with relatively few “false positives” from contaminating populations. But the limited sensitivity and sparse overlap among the infrared and X-ray subsamples indicate that the sample is very incomplete with many “false negatives.” Maps, tables, and source descriptions are provided to guide further study of star formation in these regions. In particular, the nature of ultrahard X-ray protostellar candidates without known infrared counterparts needs to be elucidated.

YOUNG STELLAR POPULATIONS IN MYStIX STAR-FORMING REGIONS: CANDIDATE PROTOSTARS

International Nuclear Information System (INIS)

Romine, Gregory; Feigelson, Eric D.; Getman, Konstantin V.; Kuhn, Michael A.; Povich, Matthew S.

2016-01-01

The Massive Young Star-Forming Complex in Infrared and X-ray (MYStIX) project provides a new census on stellar members of massive star-forming regions within 4 kpc. Here the MYStIX Infrared Excess catalog and Chandra -based X-ray photometric catalogs are mined to obtain high-quality samples of Class I protostars using criteria designed to reduce extragalactic and Galactic field star contamination. A total of 1109 MYStIX Candidate Protostars (MCPs) are found in 14 star-forming regions. Most are selected from protoplanetary disk infrared excess emission, but 20% are found from their ultrahard X-ray spectra from heavily absorbed magnetospheric flare emission. Two-thirds of the MCP sample is newly reported here. The resulting samples are strongly spatially associated with molecular cores and filaments on Herschel far-infrared maps. This spatial agreement and other evidence indicate that the MCP sample has high reliability with relatively few “false positives” from contaminating populations. But the limited sensitivity and sparse overlap among the infrared and X-ray subsamples indicate that the sample is very incomplete with many “false negatives.” Maps, tables, and source descriptions are provided to guide further study of star formation in these regions. In particular, the nature of ultrahard X-ray protostellar candidates without known infrared counterparts needs to be elucidated.

Specific methanogenic activity (SMA of industrial sludge from the aerobic and anaerobic biological treatment

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Danieli Schneiders

2013-08-01

Full Text Available In this study, specific methanogenic activity (SMA tests were performed on textile sludge and food industry sludge. The textile sludge from an activated sludge was collected at the entrance of the secondary biologic clarifier and the food sludge was collected in a UASB reactor. Once collected, the sludges were characterized and tested for SMA. It was found that the microrganisms present in the food sludge had SMA of 0.17 gCOD-CH4 gSSV.d-1 and 337.05 mL of methane production, while the microrganisms of the textile sludge presented 0.10 gCOD-CH4 gSSV.d-1 of SMA and 3.04 mL of methane production. Therefore, the food sludge was more suitable to be used as a starting inoculum in UASB.

Percutaneous Thrombin Injection to Complete SMA Pseudoaneurysm Exclusion After Failing of Endograft Placement

International Nuclear Information System (INIS)

Szopinski, Piotr; Ciostek, Piotr; Pleban, Eliza; Iwanowski, Jaroslaw; Krol, Malgorzata Serafin-; Marianowska, Agnieszka; Noszczyk, Wojciech

2005-01-01

Visceral aneurysms are potentially life-threatening vascular lesions. Superior mesenteric artery (SMA) pseudoaneurysms are a rare but well-recognized complication of chronic pancreatitis. Open surgical repair of such an aneurysm, especially in patients after previous surgical treatment, might be dangerous and risky. Stent graft implantation makes SMA pseudoaneurysm exclusion possible and therefore avoids a major abdominal operation. Percutaneous direct thrombin injection is also one of the methods of treating aneurysms in this area. We report a first case of percutaneous ultrasound-guided thrombin injection to complete SMA pseudoaneurysm exclusion after an unsuccessful endograft placement. Six-month follow-up did not demonstrate any signs of aneurysm recurrence

Recovery and residual stress of SMA wires and applications for concrete structures

International Nuclear Information System (INIS)

Choi, Eunsoo; Cho, Sung-Chul; Park, Taehyo; Hu, Jong Wan; Chung, Young-Soo

2010-01-01

In general, NiTi shape memory alloys are used for applications in civil structures. NiTi SMAs show good superelasticity and shape memory effect properties. However, for application of the shape memory effect, it is desirable for SMAs to show a wide temperature hysteresis, especially for civil structures which are exposed to severe environmental conditions. NiTiNb SMAs, in general, show a wider temperature hysteresis than NiTi SMAs and are more applicable for civil structures. This study examines the temperature hysteresis of NiTiNb and NiTi SMAs, and their recovery and residual stress are investigated. In addition, the tensile behaviors of SMA wires under residual stress are evaluated. This study explains the possible applications for concrete structures with the shape memory effect and illustrates two experimental results of concrete cylinders and reinforced concrete columns. For both tests, SMA wires of NiTiNb and NiTi are used to confine concrete using residual stress. The SMA wire jackets on the concrete cylinders increase the peak strength and the ductility compared to the plain concrete cylinders. In addition, the SMA wire jackets on reinforced concrete columns increase the ductility greatly without flexural strength degradation

Submillimeter Array (SMA) Newsletter August 2011

OpenAIRE

Blundell, Raymond

2011-01-01

Submillimeter Array (SMA) Newsletter August 2011 Blundell, Raymond Submillimeter Array Newsletter | Number 12 | August 2011 CONTENTS 1 From the Director SCIENCE HIGHLIGHTS: 2 Faint Submillimeter Sources behind Massive Lensing Clusters 5 Millimeter Imaging of the β Pictoris Debris Disk: Evidence for a Planetesimal Belt 7 Physical Properties of the Circumnuclear Starburst Ring in the Barred Galaxy NGC1097 TECHNICAL HIGHLIGHTS: 9 ...

Sistem Informasi Akademik pada SMA Hang Tuah Belawan

OpenAIRE

Tanjung, Dini Syahroni

2015-01-01

Informasi yang disampaikan oleh SMA HANG TUAH BELAWAN selama ini disebarkan melalui brosur dan cara yang seperti itu kurang efektif. Oleh karena itu dibuatlah sistem informasi akademik ini agar penyampaian informasinya lebih efektif dan efisien. 092406181

Phenotypic and genotypic studies of ALS cases in ALS-SMA families.

Science.gov (United States)

Corcia, Philippe; Vourc'h, Patrick; Blasco, Helene; Couratier, Philippe; Dangoumau, Audrey; Bellance, Remi; Desnuelle, Claude; Viader, Fausto; Pautot, Vivien; Millecamps, Stephanie; Bakkouche, Salah; Salachas, FranÇois; Andres, Christian R; Meininger, Vincent; Camu, William

2018-03-01

Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most frequent motor neuron disorders in adulthood and infancy, respectively. There is a growing literature supporting common pathophysiological patterns between those disorders. One important clinical issue for that is the co-occurrence of both diseases within a family. To collect families in which ALS and SMA patients co-exist and describe the phenotype and the genotype of ALS patients. Nine families with co-occurrence of SMA and ALS have been gathered over the last 15 years. Epidemiological, phenotype and genetic status were collected. Out of the nine families, six corresponded to the criteria of familial ALS (FALS). Clinical data were available for 11 patients out of the 15 ALS cases. Mean age of onset was 58.5 years, site of onset was lower limbs in nine cases (81.8%), median duration was 22 months. Four ALS patients carried a mutation: three mutations in SOD1 gene (G147N in two cases and one with E121G) and one repeat expansion in the C9ORF72 gene. Three patients had abnormal SMN1 copy numbers. While the high proportion of familial history of ALS cases in these ALS-SMA pedigrees could have suggested that these familial clusters of the two most frequent MND rely on a genetic background, we failed to exclude that this occurred by chance.

PENGEMBANGAN MEDIA PEMBELAJARAN PENDIDIKAN JASMANI OLAHRAGA DAN KESEHATAN BERBASIS KOMPUTER UNTUK SMA

Directory of Open Access Journals (Sweden)

Suci Cahyati

2014-04-01

Full Text Available Penelitian ini bertujuan untuk menghasilkan produk berupa CD pembelajaran pendidikan jasmani olahraga dan kesehatan berbasis komputer untuk SMA yang valid dan efektif. Penelitian ini menggunakan metode Research and Development (R&D. Media yang dikembangkan memuat materi tentang HIV/AIDS. Pengembangan media pembelajaran ini menggunakan software Adobe Flash Cs3 Professional. Media yang telah dikembangkan melalui dua tahap penelitiannya itu validasi ahli dan uji coba lapangan. Berdasarkan validasi ahli dan uji coba lapangan hasil penelitian menunjukkan produk termasuk kriteria “Sangat baik” dengan rerata skor 4,25. Hasil tes siswa mengalami peningkatan dari rerata skor pretest 5,53 dan rerata skor posttest 7,56. Berdasarkan hasil tes tersebut dapat disimpulkan bahwa media pembelajaran pendidikan jasmani olahraga dan kesehatan efektif digunakan dalam pembelajaran di SMA. Kata kunci: Pengembangan media, penjasorkes, SMA

Klasifikasi Kecamatan Berdasarkan Nilai Akhir SMA/MA di Kabupaten Aceh Selatan Menggunakan Analisis Diskriminan

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Fitriana A.R.

2015-11-01

Full Text Available Analisis diskriminan merupakan bagian dari analisis peubah ganda. Analisis diskriminan digunakan untuk memodelkan variabel tak bebas yang bersifat kualitatif dengan variabel bebas yang bersifat kuantitatif. Pada penelitian ini, analisis diskriminan lebih dari dua kelompok diterapkan pada data nilai akhir SMA/MA di Kabupaten Aceh Selatan yang bertujuan untuk mendapatkan model untuk pengklasifikasian kecamatan. Pengklasifikasian ini bertujuan untuk melihat perbedaan kualitas siswa SMA/MA yang berada di masing-masing kecamatan Kabupaten Aceh Selatan berdasarkan data nilai akhir. Variabel tak bebas yang digunakan berupa klasifikasi kecamatan berdasarkan rata-rata jumlah nilai akhir SMA/MA yang berada di masing-masing kecamatan yang dibentuk dengan K-Means Cluster. Sedangkan variabel bebas yang digunakan adalah data rata-rata nilai akhir SMA/MA untuk setiap mata pelajaran yang diujiankan pada masing-masing jurusan setiap kecamatan. Model yang didapatkan adalah dua model diskriminan untuk jurusan IPA dan IPS.

Development of SMA Actuated Morphing Airfoil for Wind Turbine Load Alleviation

Science.gov (United States)

Karakalas, A.; Machairas, T.; Solomou, A.; Riziotis, V.; Saravanos, D.

Wind turbine rotor upscaling has entered a range of rotor diameters where the blade structure cannot sustain the increased aerodynamic loads without novel load alleviation concepts. Research on load alleviation using morphing blade sections is presented. Antagonistic shape memory alloy (SMA) actuators are implemented to deflect the section trailing edge (TE) to target shapes and target time-series relating TE movement with changes in lift coefficient. Challenges encountered by the complex thermomechanical response of morphing section and the enhancement of SMA transient response to achieve frequencies meaningful for aerodynamic load alleviation are addressed. Using a recently developed finite element for SMA actuators [1], actuator configurations are considered for fast cooling and heating cycles. Numerical results quantify the attained ranges of TE angle movement, the moving time period and the developed stresses. Estimations of the attained variations of lift coefficient vs. time are also presented to assess the performance of the morphing section.

Protective effects of long-term lithium administration in a slowly progressive SMA mouse model.

Science.gov (United States)

Biagioni, Francesca; Ferrucci, Michela; Ryskalin, Larisa; Fulceri, Federica; Lazzeri, Gloria; Calierno, Maria Teresa; Busceti, Carla L; Ruffoli, Riccardo; Fornai, Francesco

2017-12-01

In the present study we evaluated the long-term effects of lithium administration to a knock-out double transgenic mouse model (Smn-/-; SMN1A2G+/-; SMN2+/+) of Spinal Muscle Atrophy type III (SMA-III). This model is characterized by very low levels of the survival motor neuron protein, slow disease progression and motor neuron loss, which enables to detect disease-modifying effects at delayed time intervals. Lithium administration attenuates the decrease in motor activity and provides full protection from motor neuron loss occurring in SMA-III mice, throughout the disease course. In addition, lithium prevents motor neuron enlargement and motor neuron heterotopy and suppresses the occurrence of radial-like glial fibrillary acidic protein immunostaining in the ventral white matter of SMA-III mice. In SMA-III mice long-term lithium administration determines a dramatic increase of survival motor neuron protein levels in the spinal cord. These data demonstrate that long-term lithium administration during a long-lasting motor neuron disorder attenuates behavioural deficit and neuropathology. Since low level of survival motor neuron protein is bound to disease severity in SMA, the robust increase in protein level produced by lithium provides solid evidence which calls for further investigations considering lithium in the long-term treatment of spinal muscle atrophy.

An improved tuned mass damper (SMA-TMD) assisted by a shape memory alloy spring

International Nuclear Information System (INIS)

Mishra, Sudib K; Gur, Sourav; Chakraborty, Subrata

2013-01-01

The tuned mass damper (TMD) is a well acclaimed passive control device for vibration control of structures. However, the requirement of a higher mass ratio restricts its applicability for seismic vibration control of civil engineering structures. Improving the performance of TMDs has been attempted by supplementing them with nonlinear restoring devices. In this regard, the ability of shape memory alloy (SMA) in dissipating energy through a hysteretic phase transformation of its microstructure triggered by cyclic loading is notable. An improved version of TMD assisted by a nonlinear shape memory alloy (SMA) spring, referred as SMA-TMD, is studied here for seismic vibration mitigation. Extensive numerical simulations are conducted based on nonlinear random vibration analysis via stochastic linearization of the nonlinear force–deformation hysteresis of the SMA. A design optimization based on minimizing the root mean square displacement of the main structure is also carried out to postulate the optimal design parameters for the proposed system. The viability of the optimal design is verified with respect to its performance under recorded earthquake motions. Significant improvements of the control efficiency and a reduction of the TMD displacement at a much reduced mass ratio are shown to be achieved in the proposed SMA-TMD over those in the linear TMD. (paper)

Imputation-based analysis of association studies: candidate regions and quantitative traits.

Directory of Open Access Journals (Sweden)

Bertrand Servin

2007-07-01

Full Text Available We introduce a new framework for the analysis of association studies, designed to allow untyped variants to be more effectively and directly tested for association with a phenotype. The idea is to combine knowledge on patterns of correlation among SNPs (e.g., from the International HapMap project or resequencing data in a candidate region of interest with genotype data at tag SNPs collected on a phenotyped study sample, to estimate ("impute" unmeasured genotypes, and then assess association between the phenotype and these estimated genotypes. Compared with standard single-SNP tests, this approach results in increased power to detect association, even in cases in which the causal variant is typed, with the greatest gain occurring when multiple causal variants are present. It also provides more interpretable explanations for observed associations, including assessing, for each SNP, the strength of the evidence that it (rather than another correlated SNP is causal. Although we focus on association studies with quantitative phenotype and a relatively restricted region (e.g., a candidate gene, the framework is applicable and computationally practical for whole genome association studies. Methods described here are implemented in a software package, Bim-Bam, available from the Stephens Lab website http://stephenslab.uchicago.edu/software.html.

Metal muscles and nerves—a self-sensing SMA-actuated hand concept

Science.gov (United States)

Simone, F.; Rizzello, G.; Seelecke, S.

2017-09-01

Bio-inspired hand-like grippers actuated by Shape Memory Alloy (SMA) wires represent an emerging new technology with potential applications in many different fields, ranging from industrial assembly processes to biomedical systems. The inherently high energy density makes SMAs a natural choice for compact, lightweight, and silent actuator systems capable of producing a high amount of work, such as hand prostheses or robotic systems in industrial human/machine environments. In this work, a concept for a compact and versatile gripping system is developed, in which SMA wires are implemented as antagonistic muscles actuating an artificial hand with three fingers. In order to combine high gripping force with sufficient actuation speed, the muscle implementation pursues a multi-wire concept with several 0.1 mm diameter NiTi wires connected in parallel, in order to increase the surface-to-volume ratio for accelerated cooling. The paper starts with an illustration of the design concept of an individual 3-phalanx-finger, along with kinematic considerations for optimal placement of SMA wires. Three identical fingers are subsequently fabricated via 3D printing and assembled into a hand-like gripper. The maximum displacement of each finger phalanx is measured, and an average phalanxes dynamic responsiveness is evaluated. SMA self-sensing is documented by experiments relating the wires change in resistance to the finger motion. Several finger force measurements are also performed. The versatility of the gripper is finally documented by displaying a variety of achievable grasping configurations.

Optimization of SMA layers in composite structures to enhance damping

Science.gov (United States)

Haghdoust, P.; Cinquemani, S.; Lecis, N.; Bassani, P.

2016-04-01

The performance of lightweight structures can be severely affected by vibration. New design concepts leading to lightweight, slender structural components can increase the vulnerability of the components to failure due to excessive vibration. The intelligent approach to address the problem would be the use of materials which are more capable in dissipating the energy due to their high value of loss factor. Among the different materials available to achieve damping, much attention has been attached to the use of shape memory alloys (SMAs) because of their unique microstructure, leading to good damping capacity. This work describes the design and optimization of a hybrid layered composite structure for the passive suppression of flexural vibrations in slender and light structures. Embedding the SMA layers in composite structure allows to combine different properties: the lightness of the base composite (e.g. fiber glass), the mechanical strength of the insert of metallic material and the relevant damping properties of SMA, in the martensitic phase. In particular, we put our attention on embedding the CuZnAl in the form of thin sheet in a layered composite made by glass fiber reinforced epoxy. By appropriately positioning of the SMA sheets so that they are subjected to the maximum curvature, the damping of the hybrid system can be considerably enhanced. Accordingly analytical method for evaluating the energy dissipation of the thin sheets with different shapes and patterns is developed and is followed by a shape optimization based on genetic algorithm. Eventually different configurations of the hybrid beam structure with different patterns of SMA layer are proposed and compared in the term of damping capacity.

Pengembangan Program Macromedia Flash 8 untuk Pembelajaran Fisika di SMA

Directory of Open Access Journals (Sweden)

Wiji Susilowati

2007-12-01

Full Text Available Tujuan penelitian adalah membuat dan mengevaluasi media pembelajaran fisika SMA menggunakan program Macromedia Flash 8. Subjek coba pada penelitian ini berjumlah 40 orang yang terdiri dari 10 siswa untuk uji coba instrumen penelitian, 10 siswa untuk ujicoba kelompok kecdl, dan 20 siswa untuk uji coba lapangan. Pengumpulan data dilakukan dengan mengguna­kan kuesioner dan tes fisika (pre-test dan post-test. Evaluasi terhadap program ditinjau dari aspek pembelajaran dan aspek media. Kritik dan saran digunakan untuk memperbaiki program. Hasil penelitian menunjukkan bahwa program Macromedia Flash 8 untuk pembelajaran fisika di SMA: (1 dirancang sesuai dengan prinsip-prinsip desain pembelajaran, (2 terbukti mampu menaikkan skor rerata tes fisika siswa sebesar 55,42%, (3 memiliki efisiensi waktu yang tinggi, (4 ditinjau dari aspek media Hinilai cukup bagus/menarik (dinilai/dikategorikan sedang oleh siswa, (5 ditinjau dari aspek pembelajaran secara keseluruhan program ini dinilai tinggi/jelas dimengerti oleh siswa, (6 ditinjau dari aspek media dinilai menarik (bagus/kategori tinggi oleh guru fisika, dan (7 ditinjau dari aspek pembelajaran juga dinilai menarik (bagus/kategori tinggi oleh guru fisika. Kata kunci: media pembelajaran fisika diSMA.

Shape Memory Alloy (SMA)-Based Launch Lock

Science.gov (United States)

Badescu, Mircea; Bao, Xiaoqi; Bar-Cohen, Yoseph

2014-01-01

Most NASA missions require the use of a launch lock for securing moving components during the launch or securing the payload before release. A launch lock is a device used to prevent unwanted motion and secure the controlled components. The current launch locks are based on pyrotechnic, electro mechanically or NiTi driven pin pullers and they are mostly one time use mechanisms that are usually bulky and involve a relatively high mass. Generally, the use of piezoelectric actuation provides high precession nanometer accuracy but it relies on friction to generate displacement. During launch, the generated vibrations can release the normal force between the actuator components allowing shaft's free motion which could result in damage to the actuated structures or instruments. This problem is common to other linear actuators that consist of a ball screw mechanism. The authors are exploring the development of a novel launch lock mechanism that is activated by a shape memory alloy (SMA) material ring, a rigid element and an SMA ring holding flexure. The proposed design and analytical model will be described and discussed in this paper.

A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA

Directory of Open Access Journals (Sweden)

Andrea Luchetti

2015-08-01

Full Text Available Spinal muscular atrophy (SMA is an inherited neuromuscular disorder and the leading genetic cause of death in infants. Despite the disease-causing gene, survival motor neuron (SMN1, encodes a ubiquitous protein, SMN1 deficiency preferentially affects spinal motor neurons (MNs, leaving the basis of this selective cell damage still unexplained. As neural stem cells (NSCs are multipotent self-renewing cells that can differentiate into neurons, they represent an in vitro model for elucidating the pathogenetic mechanism of neurodegenerative diseases such as SMA. Here we characterize for the first time neural stem cells (NSCs derived from embryonic spinal cords of a severe SMNΔ7 SMA mouse model. SMNΔ7 NSCs behave as their wild type (WT counterparts, when we consider neurosphere formation ability and the expression levels of specific regional and self-renewal markers. However, they show a perturbed cell cycle phase distribution and an increased proliferation rate compared to wild type cells. Moreover, SMNΔ7 NSCs are characterized by the differential expression of a limited number of miRNAs, among which miR-335-5p and miR-100-5p, reduced in SMNΔ7 NSCs compared to WT cells. We suggest that such miRNAs may be related to the proliferation differences characterizing SMNΔ7 NSCs, and may be potentially involved in the molecular mechanisms of SMA.

A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).

Science.gov (United States)

Luchetti, Andrea; Ciafrè, Silvia Anna; Murdocca, Michela; Malgieri, Arianna; Masotti, Andrea; Sanchez, Massimo; Farace, Maria Giulia; Novelli, Giuseppe; Sangiuolo, Federica

2015-08-06

Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder and the leading genetic cause of death in infants. Despite the disease-causing gene, survival motor neuron (SMN1), encodes a ubiquitous protein, SMN1 deficiency preferentially affects spinal motor neurons (MNs), leaving the basis of this selective cell damage still unexplained. As neural stem cells (NSCs) are multipotent self-renewing cells that can differentiate into neurons, they represent an in vitro model for elucidating the pathogenetic mechanism of neurodegenerative diseases such as SMA. Here we characterize for the first time neural stem cells (NSCs) derived from embryonic spinal cords of a severe SMNΔ7 SMA mouse model. SMNΔ7 NSCs behave as their wild type (WT) counterparts, when we consider neurosphere formation ability and the expression levels of specific regional and self-renewal markers. However, they show a perturbed cell cycle phase distribution and an increased proliferation rate compared to wild type cells. Moreover, SMNΔ7 NSCs are characterized by the differential expression of a limited number of miRNAs, among which miR-335-5p and miR-100-5p, reduced in SMNΔ7 NSCs compared to WT cells. We suggest that such miRNAs may be related to the proliferation differences characterizing SMNΔ7 NSCs, and may be potentially involved in the molecular mechanisms of SMA.

Low power consumption mini rotary actuator with SMA wires

Science.gov (United States)

Manfredi, Luigi; Huan, Yu; Cuschieri, Alfred

2017-11-01

Shape memory alloys (SMAs) are smart materials widely used as actuators for their high power to weight ratio despite their well-known low energy efficiency and limited mechanical bandwidth. For robotic applications, SMAs exhibit limitations due to high power consumption and limited stroke, varying from 4% to 7% of the total length. Hysteresis, during the contraction and extension cycle, requires a complex control algorithm. On the positive side, the small size and low weight are eminently suited for the design of mini actuators for robotic platforms. This paper describes the design and construction of a light weight and low power consuming mini rotary actuator with on-board contact-less position and force sensors. The design is specifically intended to reduce (i) energy consumption, (ii) dimensions of the sensory system, and (iii) provide a simple control without any need for SMA characterisation. The torque produced is controlled by on-board force sensors. Experiments were performed to investigate the energy consumption and performance (step and sinusoidal angle profiles with a frequency varying from 0.5 to 10 Hz and maximal amplitude of {15}\\circ ). We describe a transient capacitor effect related to the SMA wires during the sinusoidal profile when the active SMA wire is powered and the antagonist one switched-off, resulting in a transient current time varying from 300 to 400 ms.

Passive base isolation with superelastic nitinol SMA helical springs

International Nuclear Information System (INIS)

Huang, Bin; Zhang, Haiyang; Wang, Han; Song, Gangbing

2014-01-01

Seismic isolation of structures such as multi-story buildings, nuclear reactors, bridges, and liquid storage tanks should be designed to preserve structural integrity. By implementing seismic isolation technology, the deformation of superstructures can be dramatically reduced, consequently helping to protect their safety as well. In this paper, an innovative type of passive base isolation system, which is mainly composed of superelastic nitinol SMA helical springs, is developed. In order to verify the effectiveness of the proposed system, a two-story experimental steel frame model is constructed, and two superelastic SMA helical springs are thermo-mechanically built in the laboratory. To describe the nonlinear mechanical properties of the superelastic SMA helical springs under reciprocating load, a phenomenological model is presented in terms of a series of tensile tests. Afterwards, a numerical model of the two-story frame with the suggested isolation system is set up to simulate the response of the isolated frame subjected to an earthquake. Both the experimental and the numerical simulation results indicate that the proposed base isolation system can remarkably suppress structural vibrations and has improved isolation effects when compared with a steel spring isolation system. Due to the capabilities of energy dissipation as well as fully re-centering, it is very applicable to utilize the suggested isolation system in base isolated structures to resist earthquakes. (paper)

SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy.

Directory of Open Access Journals (Sweden)

Kathryn J Swoboda

2010-08-01

Full Text Available Valproic acid (VPA has demonstrated potential as a therapeutic candidate for spinal muscular atrophy (SMA in vitro and in vivo.Two cohorts of subjects were enrolled in the SMA CARNIVAL TRIAL, a non-ambulatory group of "sitters" (cohort 1 and an ambulatory group of "walkers" (cohort 2. Here, we present results for cohort 1: a multicenter phase II randomized double-blind intention-to-treat protocol in non-ambulatory SMA subjects 2-8 years of age. Sixty-one subjects were randomized 1:1 to placebo or treatment for the first six months; all received active treatment the subsequent six months. The primary outcome was change in the modified Hammersmith Functional Motor Scale (MHFMS score following six months of treatment. Secondary outcomes included safety and adverse event data, and change in MHFMS score for twelve versus six months of active treatment, body composition, quantitative SMN mRNA levels, maximum ulnar CMAP amplitudes, myometry and PFT measures.At 6 months, there was no difference in change from the baseline MHFMS score between treatment and placebo groups (difference = 0.643, 95% CI = -1.22-2.51. Adverse events occurred in >80% of subjects and were more common in the treatment group. Excessive weight gain was the most frequent drug-related adverse event, and increased fat mass was negatively related to change in MHFMS values (p = 0.0409. Post-hoc analysis found that children ages two to three years that received 12 months treatment, when adjusted for baseline weight, had significantly improved MHFMS scores (p = 0.03 compared to those who received placebo the first six months. A linear regression analysis limited to the influence of age demonstrates young age as a significant factor in improved MHFMS scores (p = 0.007.This study demonstrated no benefit from six months treatment with VPA and L-carnitine in a young non-ambulatory cohort of subjects with SMA. Weight gain, age and treatment duration were significant confounding variables that

Design and fabrication of a three-finger prosthetic hand using SMA muscle wires

Science.gov (United States)

Simone, Filomena; York, Alexander; Seelecke, Stefan

2015-03-01

Bio-inspired hand-like gripper systems based on shape memory alloy (SMA) wire actuation have the potential to enable a number of useful applications in, e.g., the biomedical field or industrial assembly systems. The inherent high energy density makes SMA solutions a natural choice for systems with lightweight, low noise and high force requirements, such as hand prostheses or robotic systems in a human/machine environment. The focus of this research is the development, design and realization of a SMA-actuated prosthetic hand prototype with three fingers. The use of thin wires (100 μm diameter) allows for high cooling rates and therefore fast movement of each finger. Grouping several small wires mechanically in parallel allows for high force actuation. To save space and to allow for a direct transmission of the motion to each finger, the SMA wires are attached directly within each finger, across each phalanx. In this way, the contraction of the wires will allow the movement of the fingers without the use of any additional gears. Within each finger, two different bundles of wires are mounted: protagonist ones that create bending movement and the antagonist ones that enable stretching of each phalanx. The resistance change in the SMA wires is measured during actuation, which allows for monitoring of the wire stroke and potentially the gripping force without the use of additional sensors. The hand is built with modern 3D-printing technologies and its performance while grasping objects of different size and shape is experimentally investigated illustrating the usefulness of the actuator concept.

An experimental and analytical study on the feasibility of SMA spring driven actuation of an iris mechanism

International Nuclear Information System (INIS)

Rajan, Aravindh; Abouseada, Mostafa; Manghaipathy, Pavithra; Ozalp, Nesrin; Majid, Feras Abdul; Salem, Ayman; Srinivasa, Arun

2016-01-01

Highlights: • An iris mechanism proposed in response to fluctuations in solar energy. • Iris motion controlled with the use of Nickel–Titanium Shape Memory Alloy springs. • Variation of the force exerted by SMA spring w.r.t. temperature tested experimentally. • An analytical expression that relates the aperture area and crank rotation is given. • SMA springs showed promising actuation mechanism as a replacement to motor. - Abstract: Variation in incoming solar energy adversely affects the temperature inside a solar reactor and lowers its efficiency. Therefore, it is important to develop a mechanism that can maintain semi-constant temperatures inside the reactor from sunrise to sunset. In this paper, we present an iris mechanism that reduces or enlarges its circular opening with the use of Nickel–Titanium Shape Memory Alloy (SMA) springs. SMA springs possess memory of their shapes at certain temperatures. Hence, by controlling the temperature of the spring, it is possible to exert different forces that may then be transferred to the variable aperture mechanism. In this study, variation of the force exerted by an SMA spring with respect to temperature was experimentally tested and the viability of an SMA spring’s use in actuating an iris mechanism aperture was examined. In order to simulate conditions under fluctuating solar radiation, a 7 kW solar simulator was used in experiments at varying power levels. It was observed that SMA springs are promising as a replacement of the actuation mechanism driven by a motor.

MODEL PENGEMBANGAN PERANGKAT PEMBELAJARAN SEJARAH BERORIENTASI METAKOGNITIF JENJANG SMA

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Cahyo Budi Utomo

2015-01-01

Full Text Available The importance of metacognitive based history learning in the high school level as requested in the “curriculum 2013” is the main background of this research. The research is focused to find the model of development of metacognitive based learning through research and development (R&D type research. The results showed an essential component in achieving successful management of metacognitive based history learning in high school education which the curriculum as a core competency analysis and basic competencies, lesson plan development, and the development of assessment tools. Development model of metacognitive based learning at high school education have main characteristic of the inclusion of explicit metacognitive learning goals and assignments and devices equipped with a rubric and assessment questionnaire. Metacognitive based history learning instructional tools that are developed in senior high school level has been carried out as optimally as possible by involving history teachers in the process of development and testing through focus group discussions and questionnaire.Keywords: Model, Instructional tool, Metacognitive, senior high school levelPentingnya orientasi metakognitif dalam perangkat pembelajaran sejarah jenjang SMA sebagaimana yang dikehendaki dalam implementasi kurikulum 2013 merupakan latar belakang utama penelitian ini. Penelitian difokuskan untuk menemukan model pengembangan perangkat pembelajaran berorientasi metakognitif melalui penelitian berjenis riset dan pengembangan (R&D. Metode penelitian R&D dilaksanakan melalui tiga tahap utama yaitu: tahap studi pendahuluan, tahap pengembangan, dan tahap uji publik. Hasil penelitian menunjukkan komponen esensial dalam mewujudkan keberhasilan penge-lolaan pembelajaran sejarah berorientasi metakognitif pada jenjang pendidikan SMA adalah kurikulum sebagai bahan analisis kompetensi inti dan kompetensi dasar, pengembangan RPP, dan pengembangan perangkat assesmen. Model

KREATIVITAS GURU BIOLOGI DALAM MEMETAKAN KOMODITAS HAYATI UNGGULAN LOKAL KE DALAM PEMBELAJARAN BIOLOGI SMA

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Asep Agus Sulaeman

2015-03-01

Full Text Available Tujuan penelitian ini adalah untuk mengetahui kreativitas guru Biologi SMA dalam memetakan topik-topik dari berbagai aspek komoditas hayati unggulan lokal melalui penggunaan metode mind map dan mengetahui kemampuan guru dalam memetakan topik-topik komoditas hayati unggulan lokal ke dalam pembelajaran Biologi di SMA. Analisis data kreativitas guru Biologi SMA dilakukan secara deskriptif kuantitatif terhadap mind map dengan menggunakan kriteria sesuai instrumen yang dikembangkan. Adapun analisis data tentang jumlah topik-topik Biologi dan jenis kegiatan pembelajaran berbasis komoditas hayati unggulan lokal dilakukan secara deskriptif kuantatif dan kualitatif. Hasil kajian ini menunjukkan nilai aspek-aspek kreativitas guru Biologi yang tinggi, yaitu kemampuan berpikir asli (91,67, peka terhadap masalah (91,67, kemampuan berpikir lancar (90, kemampuan berpikir luwes (88,33, dan kemampuan berpikir terperinci (86,67. Berdasarkan hasil pemetaan yang dilakukan guru, dapat diidentifikasi 15 topik Biologi SMA yang berkaitan dengan komoditas hayati unggulan lokal di Kabupaten Majalengka. Adapun kegiatan pembelajaran berbasis komoditas hayati unggulan yang diusulkan oleh guru tersebar di masing-masing tingkatan kelas dan semesternya dengan jumlah yang berbeda-beda.

ANALISIS KESULITAN KOGNITIF DAN MASALAH AFEKTIF SISWA SMA DALAM BELAJAR MATEMATIKA MENGHADAPI UJIAN NASIONAL

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Azis Azis

2015-11-01

Full Text Available Penelitian untuk mendeskripsikan tingkat dan letak kesulitan belajar matematika siswa pada aspek kognitif dan kategorisasi masalah belajar matematika siswa pada aspek afektif dalam menghadapi Ujian Nasional tahun pelajaran 2013/2014 SMA di Kota Baubau. Penelitian ini menggunakan penelitian dengan metode survei. Pengumpulan data yang digunakan adalah teknik pengukuran (tes diagnostik, kuisioner, dan wawancara. Hasil penelitian menunjukkan bahwa tingkat kesulitan belajar matematika yang dialami oleh siswa untuk menyelesaikan soal-soal Ujian Nasional berada pada kategori sedang; letak kesulitan belajar matematika siswa pada aspek kognitif dalam menyelesaikan soal-soal Ujian Nasional dilihat dari segi pengetahuan faktual dengan persentase interval kesulitan sebesar, segi pengetahuan konseptual dengan persentase interval kesulitan sebesar, dan segi pengetahuan prosedural dengan persentase interval kesulitan sebesar; dan kategorisasi masalah belajar matematika siswa pada kategori aspek afektif dalam menghadapi Ujian Nasional tahun pelajaran 2013/2014 SMA di Kota Baubau secara umum berada pada kategori rendah. Kata kunci: kesulitan belajar matematika, kognitif, afektif, ujian nasional SMA   AN ANALYSIS OF DIFFICULTY ON COGNITIVE AND PROBLEM ON AFFECTIVE OF SMA STUDENTS IN MATHEMATICS LEARNING FACING NATIONAL EXAMINATION Abstract This study aims to describe the degree of student’s learning difficulty of mathematics on cognitive and categorization of student’s learning problem on affective aspect in accomplishing mathematic items in facing national final exam of SMA Baubau municipality in 2013/2014 academic year. The research type uses survey method. The technique of data collecting made use of diagnostic test that is National final exam items in 2012/2013 academic year which was modified by the researcher, questionnaires, and interviews. The research result indicates that the degree of students’ learning difficulty of mathematics to accomplish

Group-SMA Algorithm Based Joint Estimation of Train Parameter and State

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Wei Zheng

2015-03-01

Full Text Available The braking rate and train arresting operation is important in the train braking performance. It is difficult to obtain the states of the train on time because of the measurement noise and a long calculation time. A type of Group Stochastic M-algorithm (GSMA based on Rao-Blackwellization Particle Filter (RBPF algorithm and Stochastic M-algorithm (SMA is proposed in this paper. Compared with RBPF, GSMA based estimation precisions for the train braking rate and the control accelerations were improved by 78% and 62%, respectively. The calculation time of the GSMA was decreased by 70% compared with SMA.

SMA-Based System for Environmental Sensors Released from an Unmanned Aerial Vehicle

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Lorenzo Pellone

2017-01-01

Full Text Available In the work at hand, a shape memory alloy (SMA-based system is presented. The system, conceived for releasing environmental sensors from ground or small unmanned aerial vehicles, UAV (often named UAS, unmanned aerial system, is made of a door, integrated into the bottom of the fuselage, a device distributor, operated by a couple of antagonistic SMA springs, and a kinematic chain, to synchronize the deployment operation with the system movement. On the basis of the specifications (weight, available space, energy supply, sensors size, etc., the system design was addressed. After having identified the main system characteristics, a representative mock-up was manufactured, featuring the bottom part of the reference fuselage. Functionality tests were performed to prove the system capability to release the sensors; a detailed characterization was finally carried out, mainly finalized at correlating the kinematic chain displacement with the SMA spring temperature and the supplied electrical power. A comparison between theoretical predictions and experimental outcomes showed good agreement.

Kajian Fisis Energi Terbarukan Panel Surya Melalui Eksperimen Sederhana untuk Siswa SMA

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Sunaryo Sunaryo

2015-12-01

Full Text Available Abstract Has conducted research on the effects of light intensity on the output voltage, current, and power. Research conducted generate data in the form of quantitative and graphs that show a link between the intensity of light, the output voltage, current, and power. The data obtained were used as sources of learning in senior high school (SMA. The implication is capable of enhancing creativity, motivation and learning outcomes of Physics subject of high school students in future studies. Keywords: light intensity, current, voltage, solar panel Abstrak Telah dilakukan penelitian tentang pengaruh intensitas cahaya terhadap tegangan output, arus, dan daya listrik. Penelitian yang dilakukan menghasilkan data dalam bentuk kuantitatif dan grafik yang menunjukkan adanya kaitan antara intensitas cahaya, tegangan output, arus, dan daya listrik. Data yang diperoleh dijadikan sebagai sumber informasi dalam pembelajaran di Sekolah Menengah Atas (SMA. Implikasinya adalah mampu meningkatkan kreativitas, motivasi, dan hasil belajar Fisika siswa SMA pada penelitian selanjutnya. Kata-kata kunci: intensitas cahaya, arus, tegangan, panel surya

Simulación basada en SMA de sistemas originalmente representados con EDO

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Ekaitz Zulueta Guerrero

2011-10-01

Full Text Available Resumen: En el presente trabajo se expone una metodología para modelar mediante un Sistema Multi-Agente (SMA sistemas biológicos y fisiológicos dinámicos con variables cuantificadas discretas, como el crecimiento y decrecimiento de poblaciones o el modelado epidemiológico de enfermedades. Se muestra un procedimiento para transformar un sistema de Ecuaciones Diferenciales Ordinarias (EDO (que modela un entorno de forma correcta en un SMA equivalente mediante un esquema basado en el método de Monte Carlo. Se utiliza un caso práctico fundamentado en un modelo matemático de Leucemia Mieloide Crónica (LMC para comparar la metodología basada en agentes con el modelado tradicional basado en un sistema de EDO. Se realiza una simulación con cada modelo (SMA y EDO y se compara los resultados obtenidos con ambas metodologías. Palabras clave: Ecuaciones diferenciales, modelo basado en agentes, Monte Carlo

PROFIL KESULITAN BELAJAR FISIKA POKOK BAHASAN KELISTRIKAN SISWA SMA DI KOTA SEMARANG

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Ani Rusilowati

2012-01-01

Full Text Available Tujuan penelitian ini adalah menentukan profil kesulitan belajar Fisika, khususnya pokok bahasan Kelistrikan yang dialami oleh siswa SMA di kota Semarang. Sampel penelitian adalah siswa SMA kelas X di kota Semarang, diambil secara cluster, dari SMA negeri dan swasta peringkat I, II, dan III, sebanyak 214 siswa. Kesulitan belajar didiagnosis dengan lima pendekatan, yaitu tujuan pembelajaran, pengetahuan prasyarat, profil materi, miskonsepsi, dan pengetahuan terstruktur. Kesulitan belajar Kelistrikan antara lain disebabkan oleh rendahnya penguasaan konsep, lemahnya kemampuan matematis, dan kekurangmampuan mengkonversi satuan. Penyebab kesulitan belajar dalam pengetahuan terstruktur adalah rendahnya kemampuan: verbal, menggunakan skema, membuat strategi pemecahan masalah, dan membuat algoritma. Hasil penelitian menunjukkan bahwa kesulitan belajar Kelistrikan rata-rata terjadi pada sub pokok bahasan: Kuat Arus Listrik, Hukum Ohm, Hambatan Penghantar, Hukum Kirchof II, Energi & Daya Listrik, dan Transformator. Sebagian siswa masih mengalami miskonsepsi terhadap konsep Hukum Ohm dan Hambatan Penghantar. Bagi siswa  sekolah peringkat III mengalami kesulitan belajar di semua aspek dan materi Kelistrikan Kata kunci : profil, kesulitan belajar, kelistrikan

Seismic fragility analysis of lap-spliced reinforced concrete columns retrofitted by SMA wire jackets

International Nuclear Information System (INIS)

Choi, Eunsoo; Park, Sun-Hee; Chung, Young-Soo; Kim, Hee Sun

2013-01-01

The aim of this study is to provide seismic fragility curves of reinforced concrete columns retrofitted by shape memory alloy wire jackets and thus assess the seismic performance of the columns against earthquakes, comparing them with reinforced concrete columns with lap-spliced and continuous reinforcement. For that purpose, this study first developed analytical models of the experimental results of the three types of columns, (1) lap-spliced reinforcement, (2) continuous reinforcement and (3) lap-spliced reinforcement and retrofitted by SMA wire jackets, using the OpenSEES program, which is oriented to nonlinear dynamic analysis. Then, a suite of ten recorded ground motions was used to conduct dynamic analyses of the analytical models with scaling of the peak ground acceleration from 0.1g to 1.0g in steps of 0.1g. From the static experimental tests, the column retrofitted with SMA wire jackets had a larger displacement ductility by a factor of 2.3 times that of the lap-spliced column, which was 6% larger compared with the ductility of the continuous reinforcement column. From the fragility analyses, the SMA wire jacketed column had median values of 0.162g and 0.567g for yield and collapse, respectively. For the yield damage state, the SMA wire jacketed column had a median value similar to the continuous reinforcement column. However, for the complete damage state, the SMA wire jacketed column showed a 1.33 times larger median value than the continuously reinforcement column. (paper)

PELAKSANAAN PROGRAM BOARDING SCHOOL DALAM PEMBINAAN MORAL SISWA DI SMA TARUNA INDONESIA PALEMBANG

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Hendriyenti H

2014-12-01

Full Text Available AbstractIndonesia nowadays faces some moral issues in teenagers scope or adult scope such as the use of drugs, violence, rascality, abortion, persecution, gambling, prostitution, and so on. Those problems are very danger for the country. Therefore, moral education is very important in this situation. The study was done at SMA Taruna Indonesia Palembang by the tittle: “the Implementation of boarding School Program for Students Moral education at SMA Taruna Indonesia Palembang”.Based on the result of the stuy, it was found that the implementation of boarding school program to educate students’moral at SMA Taruna Indonesia Palembang was applied throug dicipline implementation program and religion education program. Those two programs were applied by preventive and currative treatment. Moreover, there were some factors which support students’ moral education at SMA Taruna Indonesia Palembang such as students motivation, advisors dedication, 24 hours education and guidance, good coordination between advisors, teachers, securities, and other staff, and far location of boarding school from city center. As long as the teenager is an unstable period, there weremany difficulties in educate them. Finally,it is hoped that school stakeholders could improve the school management so that those difficulties could be solved and moral education could be applied.  Keywords: boarding school, morality building

KEEFEKTIFAN TEKNIK RELAKSASI UNTUK MENURUNKAN STRES AKADEMIK SISWA SMA

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Suyono Suyono

2016-08-01

Full Text Available Abstract: This study aims at examining the effectiveness of relaxation techniques to release students’stress and tension regarding academic within Senior High School Assádah in Gresik City. This study employed quasi-experiment design using one group pretest-posttest model. The data of this study were obtained through academic stress inventory to attain a depiction of stress level encountered by the subject. The subjects of this study were seven students of Tenth Graders in SMA Assaadah Bungah Gresik who experienced low to average stress regarding exam preparation. The data were, then, analyzed by using Wilcoxon Statistic Analysis. The result of the study indicated that relaxation technique could lower and release the level of students stress in exam preparation. Key Words: relaxation technique, student academic stress   Abstrak: Penelitian ini bertujuan untuk  menguji keefektifan teknik relaksasi untuk menurunkan stres akademik siswa SMA Ass’adah di Kota Gresik dengan menggunakan rancangan kuasi eksperimen dengan model “one group pretest posttest design. Pengumpulan data dengan menggunakan inventori stres akademik tujuannya untuk memperoleh gambaran tingkat stres akademik pada subjek penelitian. Subjek penelitian adalah siswa yang mengalami stres akademik sedang dan rendah  dalam menghadapi ujian berjumlah 7 orang siswa pada kelas X SMA Assaadah Bungah Gresik. Teknik analisis data dengan menggunakanan analisis statistic Wilcoxon. Hasil penelitian menunjukkan adanya penurunan tingkat stres akademik menjelang ujian sesudah subjek mendapatkan layanan dengan teknik  relaksasi. Kata kunci: Teknik relaksasi, stres akademik siswa

Leadership potential analysis of elementary school headmaster candidates in trenggalek region, east java Indonesia

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Widodo, BS; Sulistinah

2018-01-01

Leadership is the important component that should be possessed by headmaster candidates. Headmaster with a strong leadership potential can make a better development for school so there are many people say that “school is headmaster itself”. This study was aimed to analyze leadership potential of elementary school headmaster candidates in Trenggalek region. The samples of this study were 46 teachers who followed headmaster selection. The measurement was conducted through Leadership Potential Assessment (LPA) and interview. The result showed that there were 24 of 46 teachers who followed the test and interview had a good leadership potential to lead the elementary school. Of 24 candidates who passed the test had a good result on leadership skill, as follows: 1) quick and urgent decision making, 2) critical decision making, 3) creative decision making, and decision making based on evident that implements the four leadership skill (influence, move, develop and empower).

Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA clinical study.

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Thomas O Crawford

Full Text Available The universal presence of a gene (SMN2 nearly identical to the mutated SMN1 gene responsible for Spinal Muscular Atrophy (SMA has proved an enticing incentive to therapeutics development. Early disappointments from putative SMN-enhancing agent clinical trials have increased interest in improving the assessment of SMN expression in blood as an early "biomarker" of treatment effect.A cross-sectional, single visit, multi-center design assessed SMN transcript and protein in 108 SMA and 22 age and gender-matched healthy control subjects, while motor function was assessed by the Modified Hammersmith Functional Motor Scale (MHFMS. Enrollment selectively targeted a broad range of SMA subjects that would permit maximum power to distinguish the relative influence of SMN2 copy number, SMA type, present motor function, and age.SMN2 copy number and levels of full-length SMN2 transcripts correlated with SMA type, and like SMN protein levels, were lower in SMA subjects compared to controls. No measure of SMN expression correlated strongly with MHFMS. A key finding is that SMN2 copy number, levels of transcript and protein showed no correlation with each other.This is a prospective study that uses the most advanced techniques of SMN transcript and protein measurement in a large selectively-recruited cohort of individuals with SMA. There is a relationship between measures of SMN expression in blood and SMA type, but not a strong correlation to motor function as measured by the MHFMS. Low SMN transcript and protein levels in the SMA subjects relative to controls suggest that these measures of SMN in accessible tissues may be amenable to an "early look" for target engagement in clinical trials of putative SMN-enhancing agents. Full length SMN transcript abundance may provide insight into the molecular mechanism of phenotypic variation as a function of SMN2 copy number.Clinicaltrials.gov NCT00756821.

Superior mesenteric artery (SMA) resection during pancreatectomy for malignant disease of the pancreas: a systematic review.

Science.gov (United States)

Jegatheeswaran, Santhalingam; Baltatzis, Minas; Jamdar, Saurabh; Siriwardena, Ajith K

2017-06-01

Resection of the superior mesenteric artery (SMA) during pancreatectomy is performed infrequently and is undertaken with the aim of removing non-metastatic locally advanced pancreatic tumours. SMA resection reports also encompass resection of other visceral vessels. The consequences of resection of these different arteries are not necessarily equivalent. This is a focused systematic review of the outcome of SMA resection during pancreatectomy for cancer. A computerized search of the English language literature was undertaken for the period 1st January 2000 through 30th April 2016. The keywords "Pancreatic surgery" and "Vascular resections" were used. Thirteen studies reported 70 patients undergoing pancreatectomy with SMA resection from 10,726 undergoing pancreatectomy. Individual patient-level outcome data were available for 25. Median (range) accrual period was 132 (48-372) months. Reported peri-operative morbidity ranged from 39% to 91%. There were 5 peri-operative deaths in the 25 patients with individual-outcome data. Median survival was 11 months (95% Confidence interval 9.5-12.5 months; standard error 0.8 months). SMA resection during pancreatectomy is undertaken infrequently incurring high peri-operative morbidity and mortality. Median survival is 11 (95% CI 9.5-12.5) months. In contemporary practice there is no evidence to support SMA resection during pancreatectomy. Copyright © 2017 International Hepato-Pancreato-Biliary Association Inc. All rights reserved.

Analysis of SMA Hybrid Composite Structures in MSC.Nastran and ABAQUS

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Turner, Travis L.; Patel, Hemant D.

2005-01-01

A thermoelastic constitutive model for shape memory alloy (SMA) actuators and SMA hybrid composite (SMAHC) structures was recently implemented in the commercial finite element codes MSC.Nastran and ABAQUS. The model may be easily implemented in any code that has the capability for analysis of laminated composite structures with temperature dependent material properties. The model is also relatively easy to use and requires input of only fundamental engineering properties. A brief description of the model is presented, followed by discussion of implementation and usage in the commercial codes. Results are presented from static and dynamic analysis of SMAHC beams of two types; a beam clamped at each end and a cantilever beam. Nonlinear static (post-buckling) and random response analyses are demonstrated for the first specimen. Static deflection (shape) control is demonstrated for the cantilever beam. Approaches for modeling SMAHC material systems with embedded SMA in ribbon and small round wire product forms are demonstrated and compared. The results from the commercial codes are compared to those from a research code as validation of the commercial implementations; excellent correlation is achieved in all cases.

Force-Deformation Response of a SMA-Based Actuator Considering the Electric Current Intensity as Step-Input

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Ion-Cornel Mituletu

2015-06-01

Full Text Available The goal of the paper is to accomplish the response regarding the force-displacement characteristic evolution, of a Shape Memory Alloy (SMA actuator element. This reveals the first research stage in controlling the SMA behavior, providing important information about the heating-cooling time intervals. Step excitation of the SMA is performed by few values of electric current intensity, which produces the heating of SMA element up to 90-95 oC. To meet the testing requirements, an adequate test stand has been set up, consisting of sensors for force, displacement and temperature. The analog values provided by sensors were acquired and afterwards analyzed. The values of temperature, displacement and force were achieved, and their characteristic evolution has been performed. Thus, the time intervals are resulted and some other important aspects have been observed, regarding the delay between parameters and the temperature overshoot

Candidate region for Coffin-Siris syndrome at 7q32-->34.

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McGhee, E M; Klump, C J; Bitts, S M; Cotter, P D; Lammer, E J

2000-07-31

Coffin-Siris syndrome is characterized by intrauterine growth retardation, mental deficiency, coarse face, hypoplastic fifth fingers and nails, hirsutism, and initial difficulties with feeding. The etiology of this syndrome is unknown. We report on an 11-year-old girl with Coffin-Siris syndrome and a de novo, apparently balanced reciprocal translocation between chromosomes 7 and 22 [t(7;22)(q32;q11.2)]. The 7q breakpoint in our patient is very similar to the breakpoint reported in a previous case [McPherson et al., 1997: Am J Med Genet 71:430-433] with a balanced t(1;7)(q21.3;q34). Together, these patients provide evidence that the region 7q32-->34 is a candidate region for the gene responsible for Coffin-Siris syndrome.

Numerical and Experimental Investigation on Aerodynamic Characteristics of SMA Actuated Smart Wing Model

OpenAIRE

Iyyappan Balaguru; Sathiavelu Sendhilkumar

2013-01-01

Due to the advancements in smart actuators, morphing (changing) of aircraft wings has been investigated by increasing number of researchers in recent years. In this research article, the concept of morphing is introduced to the conventional aircraft wing model with the utilization of Shape memory alloys (SMAs). An actuating mechanism is developed and built inside the aircraft wing model along with the SMA actuators which is used to morph its shape. The aircraft wing model with the SMA actuati...

Note: A component-level frequency tunable isolator for vibration-sensitive chips using SMA beams

Energy Technology Data Exchange (ETDEWEB)

Zhang, Xiaoyong, E-mail: zhangxy@buaa.edu.cn, E-mail: yanxiaojun@buaa.edu.cn; Yan, Xiaojun, E-mail: zhangxy@buaa.edu.cn, E-mail: yanxiaojun@buaa.edu.cn [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China); Collaborative Innovation Center of Advanced Aero-Engine, Beijing 100191 (China); National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics, Beijing 100191 (China); Beijing Key Laboratory of Aero-Engine Structure and Strength, Beijing 100191 (China); Ding, Xin; Wu, Di; Qi, Junlei; Wang, Ruixin; Lu, Siwei [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China)

2016-06-15

This note presents a component-level frequency tunable isolator for vibration-sensitive chips. The isolator employed 8 U-shaped shape memory alloy (SMA) beams to support an isolation island (used for mounting chips). Due to the temperature-induced Young’s modulus variation of SMA, the system stiffness of the isolator can be controlled through heating the SMA beams. In such a way, the natural frequency of the isolator can be tuned. A prototype was fabricated to evaluate the concept. The test results show that the natural frequency of the isolator can be tuned in the range of 64 Hz–97 Hz by applying different heating strategies. Moreover, resonant vibration can be suppressed significantly (the transmissibility decreases about 65% near the resonant frequency) using a real-time tuning method.

Note: A component-level frequency tunable isolator for vibration-sensitive chips using SMA beams

International Nuclear Information System (INIS)

Zhang, Xiaoyong; Yan, Xiaojun; Ding, Xin; Wu, Di; Qi, Junlei; Wang, Ruixin; Lu, Siwei

2016-01-01

This note presents a component-level frequency tunable isolator for vibration-sensitive chips. The isolator employed 8 U-shaped shape memory alloy (SMA) beams to support an isolation island (used for mounting chips). Due to the temperature-induced Young’s modulus variation of SMA, the system stiffness of the isolator can be controlled through heating the SMA beams. In such a way, the natural frequency of the isolator can be tuned. A prototype was fabricated to evaluate the concept. The test results show that the natural frequency of the isolator can be tuned in the range of 64 Hz–97 Hz by applying different heating strategies. Moreover, resonant vibration can be suppressed significantly (the transmissibility decreases about 65% near the resonant frequency) using a real-time tuning method.

Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

Science.gov (United States)

Tsuiji, Hitomi; Iguchi, Yohei; Furuya, Asako; Kataoka, Ayane; Hatsuta, Hiroyuki; Atsuta, Naoki; Tanaka, Fumiaki; Hashizume, Yoshio; Akatsu, Hiroyasu; Murayama, Shigeo; Sobue, Gen; Yamanaka, Koji

2013-01-01

Two motor neuron diseases, amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), are caused by distinct genes involved in RNA metabolism, TDP-43 and FUS/TLS, and SMN, respectively. However, whether there is a shared defective mechanism in RNA metabolism common to these two diseases remains unclear. Here, we show that TDP-43 and FUS/TLS localize in nuclear Gems through an association with SMN, and that all three proteins function in spliceosome maintenance. We also show that in ALS, Gems are lost, U snRNA levels are up-regulated and spliceosomal U snRNPs abnormally and extensively accumulate in motor neuron nuclei, but not in the temporal lobe of FTLD with TDP-43 pathology. This aberrant accumulation of U snRNAs in ALS motor neurons is in direct contrast to SMA motor neurons, which show reduced amounts of U snRNAs, while both have defects in the spliceosome. These findings indicate that a profound loss of spliceosome integrity is a critical mechanism common to neurodegeneration in ALS and SMA, and may explain cell-type specific vulnerability of motor neurons. PMID:23255347

REKAYASA PERANGKAT LUNAK MEDIA INFORMASI SMA QURANIAH PALEMBANG

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Herlinda Kusmiati

2017-08-01

Full Text Available Seiring dengan semakin berkembangnya teknologi informasi dan meningkatnya penggunaan internet sebagai media informasi dikalangan masyarakat Indonesia. Hal ini mendorong SMA Quraniah Palembang untuk membenahi media informasi yang ada saat ini untuk meningkatkan jumlah siswa.  Media informasi yang dibuat berbasis website menggantikan Media  informasi saat ini yang masih menggunakan media brosur dan banner, dimana informasi yang diberikan masih sebatas informasi mengenai visi misi, profile, dan syarat pendaftaran siswa baru yang tidak dapat diakses dengan mudah oleh masyarakat. Dengan media informasi berbasis website dapat memberikan kemudahan kepada masyarakat dalam mendapatkan informasi mengenai profil sekolah, persyaratan pendafataran siswa baru. Selain itu, media informasi ini menyediakan informasi mengenai kegiatan-kegiatan yang ada di sekolah, ektrakulikuler siswa, serta fasilitas yang ada di sekolah. Media informasi ini dikelola oleh admin tata usaha, sehingga kesalahan-kesalahan dalam penyampaian informasi akan lebih mudah diperbaiki. Informasi-informasi mengenai SMA Quraniah Palembang dapat diakses kapanpun dan dimanapu, tidak terbatas pada salah satu wilayah saja. Media informasi ini dibuat dengan menggunakan Php & Mysql dan Waterfall sebagai metode pengembangan sistem.

Buckling analysis of SMA bonded sandwich structure – using FEM

Science.gov (United States)

Katariya, Pankaj V.; Das, Arijit; Panda, Subrata K.

2018-03-01

Thermal buckling strength of smart sandwich composite structure (bonded with shape memory alloy; SMA) examined numerically via a higher-order finite element model in association with marching technique. The excess geometrical distortion of the structure under the elevated environment modeled through Green’s strain function whereas the material nonlinearity counted with the help of marching method. The system responses are computed numerically by solving the generalized eigenvalue equations via a customized MATLAB code. The comprehensive behaviour of the current finite element solutions (minimum buckling load parameter) is established by solving the adequate number of numerical examples including the given input parameter. The current numerical model is extended further to check the influence of various structural parameter of the sandwich panel on the buckling temperature including the SMA effect and reported in details.

Stress Relaxation Effects in TiNi SMA During Superelastic Deformation: Experiment and Constitutive Model

Science.gov (United States)

Pieczyska, Elżbieta A.; Kowalewski, Zbigniew L.; Dunić, Vladimir Lj.

2017-12-01

This paper presents an investigation of thermomechanical effects related to the phenomena of stress relaxation occurring in TiNi SMA subjected to modified program of displacement-controlled tension. The deformation data were taken from testing machine, whereas the temperature changes accompanying the exothermic/endothermic martensite forward/reverse transformation were measured by infrared camera. At the advanced stages of the transformations, the strain was kept constant for a few minutes and the SMA load and temperature were recorded continuously. As a consequence, the stress and temperature changed significantly during the loading stops. A large stress drop, caused by the transformation, was observed during the relaxation stage in both courses of the SMA loading and unloading. Moreover, the non-uniform temperature distribution, reflecting macroscopically inhomogeneous transformation, lapsed while the strain was kept constant, yet restarted at the end of the relaxation stop and developed at the reloading stage. Along with the experimental results, the mechanical and thermal responses induced by the transformation were obtained by 3D coupled thermomechanical numerical analysis, realized in partitioned approach. Latent heat production was correlated with an amount of the martensitic volume fraction. The stress and temperature drops recorded during the experiment were satisfactorily reproduced by the model proposed for the SMA thermomechanical coupling.

A fuzzy PID-controlled SMA actuator for a two-DOF joint

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Shi Zhenyun

2014-04-01

Full Text Available Shape memory alloy (SMA actuator is a potential advanced component for servo-systems of aerospace vehicles and aircraft. This paper presents a joint with two degrees of freedom (DOF and a mobility range close to ±60° when driven by SMA triple wires. The fuzzy proportional-integral-derivative (PID-controlled actuator drive was designed using antagonistic SMA triple wires, and the resistance feedback signal made a closed loop. Experiments showed that, with the driving responding frequency increasing, the overstress became harder to be avoided at the position under the maximum friction force. Furthermore, the hysteresis gap between the heating and cooling paths of the strain-to-resistance curve expanded under this condition. A fuzzy logic control was considered as a solution, and the curves of the wires were then modeled by fitting polynomials so that the measured resistance was used directly to determine the control signal. Accurate control was demonstrated through the step response, and the experimental results showed that under the fuzzy PID-control program, the mean absolute error (MAE of the rotation angle was about 3.147°. In addition, the investigation of the external interference to the system proved the controllable maximum output.

Perancangan Sistem Informasi SMA Negeri 1 Babalan Dengan Menggunakan Pemrograman PHP Dan MySQL

OpenAIRE

Yulita, Devi

2014-01-01

Tulisan ini bertujuan untuk membangun suatu sistem informasi pada SMA Negeri 1 Babalan. Sistem ini dikembangkan dengan menggunakan perangkat lunak PHP, MySQL, Apache, dan Mozilla Firefox juga software pembantu lainnya seperti Adobe Dreamweaver CS5. Tujuan dari sistem informasi ini adalah untuk menyajikan informasi profil sekolah, visi, misi dan tujuan, daftar siswa, daftar guru. Merancang sebuah website untuk membantu siswa dalam memperoleh informasi SMA Negeri 1 Babalan dan website ini dapat...

FRECUENCIAS NATURALES EN VIGAS ACTIVAMENTE TORSIONADAS USANDO ALAMBRES DE ALEACIÓN CON MEMORIA DE FORMA (SMA | NATURAL FREQUENCIES IN ACTVELY TWISTED BEAMS USING SHAPE MEMORY ALLOY (SMA WIRES

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Gaetano Starlacci

2016-08-01

Full Text Available Changes in the geometry and stiffness of structural members can be obtained using Shape Memory Alloys (SMA wires, previously stretched, and externally attached to the member in a helical pattern. The wire was modeled assuming transformation from a pure martensitic phase to a pure austenitic phase. Natural frequency values before and after the SMA wire activation attached to the beam were calculated using the finite element method and these values were compared with those obtained from a model developed for pre-twisted stress-free cantilever members. The results obtained showed the active torsion influence over the structural element in the values of natural frequencies calculated.

Self-repairing performance of concrete beams strengthened using superelastic SMA wires in combination with adhesives released from hollow fibers

International Nuclear Information System (INIS)

Kuang Yachuan; Ou Jinping

2008-01-01

By taking advantage of the superelastic effect of shape memory alloy (SMA) and the cohering characteristic of repairing adhesive, a smart self-repairing concrete beam with damage self-repairing performance has been developed. In order to verify the potential self-repairing capacity of smart concrete beams reinforced with SMA wires and brittle fibers containing adhesives, static loading tests were conducted. Experimental results show that the superelastic SMA wires added self-restoration capacity to concrete beams, the deflection of the beams reversed and the crack closed almost completely after unloading. After the release of adhesive from the broken-open fibers into the cracks from the first loading, stress was redistributed to the uncracked section where a new crack was formed, while the sealed crack remained closed during reloading for the smart concrete beams reinforced with SMA wires and brittle fibers containing adhesives. While the original cracks experienced reopening, the load was carried directly by the wires during reloading for concrete beams reinforced with SMA wires

EFEKTIVITAS FOCUS GROUP DISCUSSION UNTUK MENGURANGI STRES PADA SISWA SMA YANG AKAN MENGHADAPI UJIAN AKHIR NASIONAL

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Dina Aprilia

2016-10-01

Full Text Available This research is aimed to find the effectivity of Focus Group Discussion (FGD to decrease the feeling stress for senior high school students (SMA who will face the national final examination (UAN. Stress on SMA students is a circumstance which gets negative assessment. It intimidates and pushes the students, in this case is UAN would appear a reaction such as emotional disorder, cognition, physiology and behavior disorder of SMA students. This research concerned 21 SMA students in grade XII, who had high stress level in facing UAN. The subjects were divided into two groups. First group was the experiment group (include 11 students and it was the group who got the FGD treatment. The second group was control group (include 10 students and this group didn’t get the FGD treatment. Collecting data was done by using Stress Scale in facing UAN. It was given (a before FGD (pre-test and (b after FGD (post-test. The hypothesis is examined by using difference examination (t-test by comparing mean pre-test and post-test. The result showed that there was a significant influence to decrease the stress in SMA students who were in experiment group (t = 6,540, p < 0,01 after they got FGD treatment. Experiment group had decreased the stress score to face UAN (Mean=7,476.

Faktor Penghambat Proses Layanan Konseling Individual di SMA se-Kota Cilacap

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Fenti Nurindahsari

2015-12-01

Full Text Available Berdasarkan penuturan guru BK di salah satu SMA di kota Cilacap yang pernah menjadi tempat observasi oleh peneliti, ditemukan fenomena terkait dengan layanan konseling individual di sekolah tersebut yang tidak sesuai dengan teori-teori mengenai konseling individual yang ada dalam bimbingan konseling. Contoh yang tidak sesuai dengan teori  ketika proses konseling berakhir guru BK di sekolah tersebut tidak ada upaya tindak lanjut. Tujuan penelitian ini untuk mengetahui faktor penghambat proses layanan konseling individual di SMA sekota Cilacap. Jenis penelitian deskriptif kuantitatif. Populasi dalam penelitian ini adalah konselor yang ada di SMA sekota Cilacap. Teknik sampel untuk konselor yang dipilih praktikan adalah sampling jenuh. Instrumen yang digunakan adalah angket. Validitas menggunakan rumus Product Moment. Uji reliabitilitas menggunakan rumus Alpha. Metode analisis data menggunakan deskriptif persentase. Hasil penelitian menunjukan faktor internal penghambat berasal dari konselor dalam kriteria tinggi (71,74% faktor eksternal penghambat termasuk kriteria tinggi yaitu norma (71,59%, sarpras (71,38% dan lingkungan fisik (72,39%. Dapat disimpulkan hambatan yang ada dalam proses layanan konseling individual di SMA sekota Cilacap berasal dari faktor internal dan eksternal yang memiliki kriteria yang sama yaitu dalam kategori tinggi. Based the narrative counseling teacher in one high school in Cilacap town that  once a place observation, discovered the phenomenon associated with individual counseling services in the school is not in accordance with the theories about the existing individual counseling in counseling. Examples that don’t fit with theory when the counseling process ends counseling teacher the school is’n follow-up effort. The purpose of this study to determine inhibiting factors individual counseling service process In senior high school Cilacap derby. Pupolasi in research is senior high school counselors. Technical

PENGARUH LINGKUNGAN KELUARGA, LINGKUNGAN SEKOLAH, DISIPLIN BELAJAR DAN MOTIVASI BELAJAR TERHADAP PRESTASI BELAJAR EKONOMI SISWA SMA KELAS XI IPS SMA PGRI 1 TAMAN PEMALANG

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Iyut Sustiasih Sudikno

2014-02-01

Full Text Available Penelitian ini bertujuan untuk mengetahui pengaruh lingkungan keluarga, lingkungan sekolah dan disiplin belajar terhadap prestasi belajar melalui motivasi belajar siswa kelas XI IPS SMA PGRI 1 Taman Pemalang. Subyek penelitian ini adalah siswa kelas XI IPS SMA PGRI 1 Taman Pemalang. Latar belakang penelitian ini adalah prestasi belajar siswa kelas XI IPS yang kurang optimal. Penelitian ini merupakan penelitian kuantitatif. Variabel bebas yang dikaji dalam penelitian ini adalah Lingkungan Keluarga (X1, Lingkungan Sekolah (X2, Disiplin Belajar (X3. Variabel terikat adalah Prestasi Belajar (Y2 dan Variabel intervening adalah Motivasi Belajar (Y1. Metode pengumpulan data yang digunakan adalah dokumentasi dan angket. Metode analisis data yaitu analisis deskriptif persentase dan analisis uji jalur (path analysis. Hasil analisis regresi linier berganda diperoleh persamaan regresi Y1 = 10,011 + 0,233X1 + 0,391X 2+ 0,522X3 +e1, dan Y2 = 71,062 + 0,227X1 + 0,704Y1 + 0,349X3 + e2. Hasil analisi jalur menunjukkan bahwa pengaruh secara tidak langsung (LK-PB sebesar 22,7%, (LS-PB sebesar 10,5%, (DB-PB sebesar 34,9%, (MB-PB sebesar 70,4% dan pengaruh secara tidak langsung (LK-MB-PB sebesar 16,4%, (LS-MB-PB sebesar 27,5%, (DP-MB-PB sebesar 36,7%. This research aims to determine the effect of on family environment, school environment, learning discipline on students’ achievements through student motivation SMA PGRI 1 Taman Pemalang. The subjects were students of class XI IPS Students of SMA PGRI 1 Taman Pemalang. The background of this research is the student’ achievements XI IPS Stuents of SMA PGRI 1 Taman Pemalang. This research is a quantitative study. The independent variables were examined in this study is family environment (X1, school environment (X2, learning discipline (X3. The dependent variable is the students, achievements (Y2 and the intervening variable is learning motivation (Y1. Data collection methods used are documentation and

Studi Kasus Pengembangan Program Bimbingan dan Konseling di SMA Negeri Kota Surakarta

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Anna Annisa

2015-12-01

Full Text Available Penelitian berdasarkan fenomena program bimbingan dan konseling di sekolah belum berjalan dengan baik terutama pada bagian perencanaan dan pelaksanaan program BK. Tujuan penelitian ini untuk mengetahui pengembangan program di SMA Negeri 7 Surakarta dan SMA N 8 Surakarta mulai dari (1 pelaksanaan asesmen kebutuhan melalui pengumpulan data, (2 interpretasi data asesmen kebutuhan, (3 penetapan prioritas kebutuhan, (4 penetapan tujuan program, (5 penetapan prosedur program, dan (6 perencanaan bagi perbaikan peningkatan penyempurnaan program. Jenis penelitian ini adalah deskriptif kualitatif dengan pendekatan studi kasus. Penelitian ini melibatkan guru BK di SMA Negeri Kota Surakarta. Metode pengumpulan data yang digunakan adalah menggunakan wawancara, observasi dan dokumentasi. Teknik analisis data menggunakan pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Simpulan dari penelitian ini adalah pada SMA N 7 Surakarta pengembangan program fokus pada penggunaan instrumen dalam asesmen, sasaran asesmen, kesesuaian asesmen dengan kebutuhan siswa, layann klasikal dan layanan kelompok. Sedangkan SMA N 8 Surakarta  difokuskan pada penentuan prioritas kebutuhan dan analisis data kebutuhan siswa. This research of program guidance and counselling in schools has not fully well especially at the planning and execution of counseling and guidance program. The purpose to know the development program at senior high school 7 Surakarta and senior high school 8 Surakarta ranging from (1 the implementation of needs assessment through data collection, data interpretation (2 the assessment of needs, (3 the determination of priority needs, (4 The goal setting program, (5 the determination of the procedures of the program, and (6 The planning for improvements to increase refinement program. Type of this research is descriptive qualitative approach to case studies. This research involves guidance and counseling teachers in senior high school of

Pemodelan Enterprise Architecture Sistem Informasi Akademik SMA PL Don Bosko Semarang Dengan Framework Zachman

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Maria Alfonsa Chintia Dea Prananingrum

2017-05-01

Full Text Available Abstrak SMA PL Don Bosko Semarang belum dapat memanfaatkan teknologi komputer secara optimal karena masih menggunakan cara manual dalam pengelolaan berbagai macam data akademik sehingga memberikan masalah seperti lambatnya dalam pembuatan laporan yang menyulitkan kepala sekolah dalam pengambilan keputusan. Oleh sebab itu, SMA PL Don Bosko Semarang membutuhkan Sistem Informasi Akademik untuk memberikan kemudahan dalam mengelola berbagai macam data akademik secara terintegrasi serta memberikan layanan yang lebih baik kepada siswanya. Sebuah model architecture enterprise Sistem Informasi Akademik dibutuhkan agar meminimalisir kegagalan ketika menerapkan sistem tersebut sekaligus dapat berjalan sesuai kebutuhan di SMA PL Don Bosko Semarang. Metode analisis dalam penelitian ini menggunakan Framework Zachman yang memberikan pondasi dalam membantu menyediakan struktur dasar organisasi sehingga dapat mendukung perancangan dan pengembangan sistem informasi suatu organisasi. Hasil dari penelitian ini berupa blueprint (cetak biru pemodelan Sistem Informasi Akademik. Kata kunci— sistem informasi akademik, architecture enterprise, framework zachman, bluprint

Design and demonstration of a fish robot actuated by a SMA-driven actuation system

Science.gov (United States)

Le, Chan H.; Nguyen, Quang S.; Park, Hoon C.

2010-04-01

This paper presents a concept of a fish robot actuated by an SMA-based actuator. The bending-type actuator system is composed of a 0.1mm diameter SMA wire and a 0.5mm thick glass/epoxy strip. The SMA wire is installed to the bent composite strip. The actuator can produce about 200gf of blocking force and 3.5mm displacement at the center of the glass/epoxy strip. The bending motion of the actuator is converted into the tail-beat motion of a fish robot through a linkage system. The fish robot is evaluated by measuring the tail-beat angle, swimming speed and thrust produced by the fish robot. The tail-beat angle is about 20° and the maximum swimming speed is about 1.6cm/s. The measured thrust is about 0.4gf when the fish robot is operated at 0.9Hz.

Construction of a yeast artifical chromosome contig spanning the spinal muscular atrophy disease gene region

Energy Technology Data Exchange (ETDEWEB)

Kleyn, P.W.; Wang, C.H.; Vitale, E.; Pan, J.; Ross, B.M.; Grunn, A.; Palmer, D.A.; Warburton, D.; Brzustowicz, L.M.; Gilliam, T.G. (New York State Psychiatric Institute, NY (United States)); Lien, L.L.; Kunkel, L.M. (Howard Hughes Medical Institute, Boston, MA (United States))

1993-07-15

The childhood spinal muscular atrophies (SMAs) are the most common, serious neuromuscular disorders of childhood second to Duchenne muscular dystrophy. A single locus for these disorders has been mapped by recombination events to a region of 0.7 centimorgan (range, 0.1-2.1 centimorgans) between loci D5S435 and MAP1B on chromosome 5q11.2-13.3. By using PCR amplification to screen yeast artificial chromosome (YAC) DNA pools and the PCR-vectorette method to amplify YAC ends, a YAC contig was constructed across the disease gene region. Nine walk steps identified 32 YACs, including a minimum of seven overlapping YAC clones (average size, 460 kb) that span the SMA region. The contig is characterized by a collection of 30 YAC-end sequence tag sites together with seven genetic markers. The entire YAC contig spans a minimum of 3.2 Mb; the SMA locus is confined to roughly half of this region. Microsatellite markers generated along the YAC contig segregate with the SMA locus in all families where the flanking markers (D5S435 and MAP1B) recombine. Construction of a YAC contig across the disease gene region is an essential step in isolation of the SMA-encoding gene. 26 refs., 3 figs., 1 tab.

iSmaRT: a toolkit for a comprehensive analysis of small RNA-Seq data.

Science.gov (United States)

Panero, Riccardo; Rinaldi, Antonio; Memoli, Domenico; Nassa, Giovanni; Ravo, Maria; Rizzo, Francesca; Tarallo, Roberta; Milanesi, Luciano; Weisz, Alessandro; Giurato, Giorgio

2017-03-15

The interest in investigating the biological roles of small non-coding RNAs (sncRNAs) is increasing, due to the pleiotropic effects of these molecules exert in many biological contexts. While several methods and tools are available to study microRNAs (miRNAs), only few focus on novel classes of sncRNAs, in particular PIWI-interacting RNAs (piRNAs). To overcome these limitations, we implemented iSmaRT ( i ntegrative Sm all R NA T ool-kit), an automated pipeline to analyze smallRNA-Seq data. iSmaRT is a collection of bioinformatics tools and own algorithms, interconnected through a Graphical User Interface (GUI). In addition to performing comprehensive analyses on miRNAs, it implements specific computational modules to analyze piRNAs, predicting novel ones and identifying their RNA targets. A smallRNA-Seq dataset generated from brain samples of Huntington's Disease patients was used here to illustrate iSmaRT performances, demonstrating how the pipeline can provide, in a rapid and user friendly way, a comprehensive analysis of different classes of sncRNAs. iSmaRT is freely available on the web at ftp://labmedmolge-1.unisa.it (User: iSmart - Password: password). aweisz@unisa.it or ggiurato@unisa.it. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

Peningkatan Mutu Pendidikan SMA Muhammadiyah 2 Sidoarjo sebagai Sekolah Berkategori The Outstanding School of Muhammadiyah

OpenAIRE

Hidayatulloh Hidayatulloh

2016-01-01

This article examines about improving the education quality of SMA Muhammadiyah 2 Sidoarjo as the Outstanding School of Muhammadiyah. This article reveals that the quality improvement of SMA Muhammadiyah 2 Sidoarjo was conducted through: the arrangement of school program and self evaluation, the reinforcement of vision, mission and education objective, the reinforcement of leadership and teamwork, the improvement of teachers and educators competence, the improvement learners quality input, th...

PKCδ as a regulator for TGFβ1-induced α-SMA production in a murine nonalcoholic steatohepatitis model.

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Su Jin Lee

Full Text Available The precise mechanism of TGFβ1 signaling in the progression of non-alcoholic steatohepatitis (NASH has remained unclear. In particular, a potential regulatory mechanism by which PKCδ affects profibrogenic gene expression had never been explored. In this study, therefore, the role of PKCδ in TGFβ1 mediated α-SMA expression was investigated using NASH model mice. In preparation of the NASH model, male C57BL6/J mice were fed a methionine-choline-deficient (MCD diet for 3 weeks, after which time they were intraperitoneally injected with lipopolysaccharide (LPS. In addition, Tlr4(Lps-d (CH3/HeJ mice were used to demonstrate the TGFβ1 signaling's dependency on TLR4 induction. Liver histology and hepatic hepatitis markers were investigated, and hepatic gene expression levels were determined by real-time PCR. Acute liver injury by LPS injection specifically elevated not only α-SMA expression but also phospho-PKCδ in this model. In contrast, Tlr4(Lps-d (CH3/HeJ and blockade of TGFβ1 receptor by SB431542 resulted in a significant reduction of PKCδ activation and α-SMA expression. Moreover, the TGFβ1-induced α-SMA production was significantly reduced by a specific PKCδ inhibitor. These findings suggested that PKCδ plays a critical role in TGFβ1-induced α-SMA production in a NASH model. Thus, this was the first demonstration of the involvement of PKCδ in the regulation of α-SMA expression in NASH liver tissues, and the impaired induction of PKCδ phosphorylation by LPS in a steatohepatitis condition. Interestingly, treatment by PKCδ inhibitor caused dramatic reduction of myofibroblast activation, indicating that PKCδ represents a promising target for treating NASH.

Mechanical behavior and fatigue performance of SMA short fiber reinforced MMC

Science.gov (United States)

Al-Matar, Basem Jawad

The mechanical behavior and performance of Shape Memory Alloy (SMA) short fiber NiTi reinforced Al was experimentally investigated for monotonic and fatigue test Al 6061 NiTi-SiC T6 was superior to unreinforced materials as well as to the reinforced Al T4. Taya three-dimensional model was performed on the monotonic tensile test at room temperature. It showed good agreement with experimental results. In order to utilize the compressive criterion for SMA, the NiTi reinforced Al composite was cooled at -10°C and prestrained at 1.2%. Beyond this limit composite suffered from damage. The net enhancement of SMA effect was around 10 MPa on composite yield stress. Results showed that the elastic constant for the composite did not change with loading and unloading suggesting that the inelastic behavior is plasticity. Further investigation on the inelastic behavior model as damage and/or plasticity by evaluating Poisson's ratio during loading was carried out by Adaptive Image Correlation Technique for Full-Field Strain Measurement. Poisson's ratio increased from around 0.33 to 0.5 demonstrating that it is plasticity that is responsible for the inelastic behavior. Scanning electron microscopy was also used and confirmed model results. The overall damage-behavior was quantified in terms of the post fatigue failure strength for low-cycle fatigue tests. Power law model was best to fit experimental findings.

Minimizing the Moisture Damage and Drain down of Iraqi SMA Mixtures Using Waste Additives

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Ali Al-Hadidy

2013-04-01

Full Text Available This research deals with the viability of using polyester fiber (PF, crumb rubber tire (CRT and cellulose fiber (CF as stabilizing waste additives in producing Iraqi SMA mixtures that sustain drain down phenomenon and moisture damage sensitivity. Different ratios of these additives (0.1, 0.2, and 0.3% by weight of aggregate and filler were mixed with 40/50 paving asphalt by means of dry process. Unmodified and modified SMA mixtures were subjected to drain down, Marshall, static indirect tensile strength, tensile stiffness modulus, static compressive strength, tensile strength ratio and index of retained strength tests. A set of regression equations between these tests were established. In addition, an optimization table based on these tests, which can be used to select the type or amount of additive for any field applications has been determined and reported. The results indicated that the inclusion of these additives in SMA mixtures can satisfy the performance requirement of high temperature and much rain zone.

Free vibration response of a multilayer smart hybrid composite plate with embedded SMA wires

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K. Malekzadeh

Full Text Available In this paper, free vibration response of a hybrid composite plate was studied. Effects of some geometrical, physical and material parameters on response of the composite plates embedded with shape memory alloy (SMA wires were investigated, which have not been reported in the literature thus far. Some of these parameters included important factors affecting free vibration response of the smart hybrid composite plates. The SMA wires were embedded within the layers of the composite laminate. First-order shear deformation theory (FSDT was utilized to obtain the governing equations of hybrid composite plates. Transverse shear and rotary inertia effects of the plate were taken into consideration. For simply-supported boundary conditions, systematic closed form solutions were obtained by Navier's technique. It was established that dynamic behavior of the smart hybrid composite plate depended on various parameters such as volume fraction, temperature dependent recovery stress and tensile pre-strain of SMA wires and aspect ratio of the laminated hybrid plate.

RTC simulations on large branched sewer systems with SmaRTControl.

Science.gov (United States)

de Korte, Kees; van Beest, Dick; van der Plaat, Marcel; de Graaf, Erno; Schaart, Niels

2009-01-01

In The Netherlands many large branched sewer systems exist. RTC can improve the performance of these systems. The objective of the universal algorithm of SmaRTControl is to improve the performance of the sewer system and the WWTP. The effect of RTC under rain weather flow conditions is simulated using a hydrological model with 19 drainage districts. The system related inefficiency coefficient (SIC) is introduced for assessment of the performance of sewer systems. The performance can be improved by RTC in combination with increased pumping capacities in the drainage districts, but without increasing the flow to the WWTP. Under dry weather flow conditions the flow to the WWTP can be equalized by storage of wastewater in the sewer system. It is concluded that SmaRTControl can improve the performance, that simulations are necessary and that SIC is an excellent parameter for assessment of the performance.

GENÇ PARTİ'Yİ ANLAMAK (Parti, Lider ve Kitle Üzerine Bir Çalısma)

OpenAIRE

TÜRK, Hasan Bahadır

2007-01-01

Türk, Hasan Bahadır, Genç Parti’yi Anlamak: Parti, Lider ve Kitle Üzerine BirÇalısma, Doktora Tezi, Danısman: Doç.Dr. Aykut Çelebi, 399 s.ÖZETBu çalısmanın amacı; Genç Parti’nin temel yapısal özelliklerine ısık tutmaktır. Çalısma;Genç Parti’yi lider, kadro, parti tipolojisi, ideoloji ve söylem gibi parçalarındanhareketle analiz etmeye ve kitleyle kurdugu iliskiyi tartısmaya odaklanacaktır. Çalısma,üç ana bölümden olusmaktadır. lk iki bölümde Uzanlar’ın genel yapısı, yükselis veçöküs süreci Ge...

PELATIHAN PENULISAN KARYA ILMIAH BIDANG SOSIAL ( HUKUM DI SMA NEGERI 3 DENPASAR

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I KETUT SUDIARTA

2012-09-01

Full Text Available ABSRACT Training of Constructing Scientific Report on Social Major (Law has done on SMA Negeri 3 Denpasar, by the Guiding Team of the Lecturers of Law Faculty of Udayana University through a practice of constructing a report in a class through a workshop. Aproximately, 40% are for meanwhile, 60% are by practice of composing and providing some reference which is related to the constructing of a social-scientific report, and there all are done well so far. This fact was indicated by the responds which were given by the students of SMA Negeri 3 Denpasar, especially for those who join the KIR group.This activity has been done once a week.

A Novel SMA-based Concept for Airfoil Structural Morphing

Science.gov (United States)

Barbarino, S.; Pecora, R.; Lecce, L.; Concilio, A.; Ameduri, S.; Calvi, E.

2009-08-01

The adaptive structures concept is of great interest in the aerospace field because of the several benefits which can be accomplished in the fields including noise reduction, load alleviation, weight reduction, etc., at a level in which they can be considered as compulsory in the design of future aircraft. Improvements in terms of the aerodynamic efficiency, aeroelastic behavior, stability, and manoeuvrability performance have already been proved through many international studies in the past. In the family of the Smart Materials, Shape Memory Alloys (SMA) seem to be a suitable solution for many static applications. Their high structural integrability in conjunction with actuation capabilities and a favorable performance per weight ratio, allows the development of original architectures. In this study, a morphing wing trailing edge concept is presented; morphing ability was introduced with the aim of replacing a conventional flap device. A compliant rib structure was designed, based on SMA actuators exhibiting structural potential (bearing external aerodynamic loads). Numerical results, achieved through a FE approach, are presented in terms of trailing edge induced displacement and morphed shape.

S&MA Internship to Support Orion and the European Service Module

Science.gov (United States)

Hutcheson, Connor

2016-01-01

As a University Space Research Association (USRA) intern for NASA Johnson Space Center (JSC) during the summer 2016 work term, I worked on three main projects for the Space Exploration Division (NC) of the Safety and Mission Assurance (S&MA) Directorate. I worked on all three projects concurrently. One of the projects involved facilitating the status and closure of technical actions that were created during European Service Module (ESM) safety reviews by the MPCV Safety & Engineering Review Panel (MSERP). The two main duties included accurately collecting and summarizing qualitative data, and communicating that information to the European Space Agency (ESA) and Airbus (ESA's prime contractor) in a clear, succinct and precise manner. This project also required that I create a report on the challenges and opportunities of international S&MA. With its heavy emphasis on soft skills, this project taught me how to communicate better, by showing me how to present and share information in an easy-to-read and understandable format, and by showing me how to cooperate with and culturally respect international partners on a technical project. The second project involved working with the Orion Thermal Protection System (TPS) Process Failure Modes and Effects Analysis (PFMEA) Working Group to create the first full version of the Orion TPS PFMEA. The Orion TPS PFMEA Working Group met twice a week to analyze the Avcoat block installation process for failure modes, the failure modes effects, and how such failure modes could be controlled. I was in charge of implementing changes that were discussed in meeting, but were not implemented real time. Another major task included creating a significant portion of the content alongside another team member outside the two weekly meetings. This project caused me to become knowledgeable about TPS, heatshields, space-rated manufacturing, and non-destructive evaluation (NDE). The project also helped me to become better at working with a small

Transcranial direct current stimulation (tDCS) to the supplementary motor area (SMA) influences performance on motor tasks.

Science.gov (United States)

Hupfeld, K E; Ketcham, C J; Schneider, H D

2017-03-01

The supplementary motor area (SMA) is believed to be highly involved in the planning and execution of both simple and complex motor tasks. This study aimed to examine the role of the SMA in planning the movements required to complete reaction time, balance, and pegboard tasks using anodal transcranial direct current stimulation (tDCS), which passes a weak electrical current between two electrodes, in order to modulate neuronal activity. Twenty healthy adults were counterbalanced to receive either tDCS (experimental condition) or no tDCS (control condition) for 3 days. During administration of tDCS, participants performed a balance task significantly faster than controls. After tDCS, subjects significantly improved their simple and choice reaction time. These results demonstrate that the SMA is highly involved in planning and executing fine and gross motor skill tasks and that tDCS is an effective modality for increasing SMA-related performance on these tasks. The findings may be generalizable and therefore indicate implications for future interventions using tDCS as a therapeutic tool.

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

International Nuclear Information System (INIS)

Michels, Evi; Speleman, Frank; Hoebeeck, Jasmien; De Preter, Katleen; Schramm, Alexander; Brichard, Bénédicte; De Paepe, Anne; Eggert, Angelika; Laureys, Geneviève; Vandesompele, Jo

2008-01-01

Recurrent loss of part of the long arm of chromosome 11 is a well established hallmark of a subtype of aggressive neuroblastomas. Despite intensive mapping efforts to localize the culprit 11q tumour suppressor gene, this search has been unsuccessful thus far as no sufficiently small critical region could be delineated for selection of candidate genes. To refine the critical region of 11q loss, the chromosome 11 status of 100 primary neuroblastoma tumours and 29 cell lines was analyzed using a BAC array containing a chromosome 11 tiling path. For the genes mapping within our refined region of loss, meta-analysis on published neuroblastoma mRNA gene expression datasets was performed for candidate gene selection. The DNA methylation status of the resulting candidate gene was determined using re-expression experiments by treatment of neuroblastoma cells with the demethylating agent 5-aza-2'-deoxycytidine and bisulphite sequencing. Two small critical regions of loss within 11q23 at chromosomal band 11q23.1-q23.2 (1.79 Mb) and 11q23.2-q23.3 (3.72 Mb) were identified. In a first step towards further selection of candidate neuroblastoma tumour suppressor genes, we performed a meta-analysis on published expression profiles of 692 neuroblastoma tumours. Integration of the resulting candidate gene list with expression data of neuroblastoma progenitor cells pinpointed CADM1 as a compelling candidate gene. Meta-analysis indicated that CADM1 expression has prognostic significance and differential expression for the gene was noted in unfavourable neuroblastoma versus normal neuroblasts. Methylation analysis provided no evidence for a two-hit mechanism in 11q deleted cell lines. Our study puts CADM1 forward as a strong candidate neuroblastoma suppressor gene. Further functional studies are warranted to elucidate the role of CADM1 in neuroblastoma development and to investigate the possibility of CADM1 haploinsufficiency in neuroblastoma

Hubungan antara Aktivitas Fisik Terhadap Memori Kerja Murid SMA Don Bosco III Bekasi

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Michelle Clarissa Junaidi

2017-03-01

Full Text Available Latar belakang. Memori kerja merupakan bagian dari memori jangka pendek yang berperan penting dalam membantu proses pembelajaran dan dipengaruhi oleh aktivitas fisik, memori kerja yang rendah akan menimbulkan kesulitan untuk menerima informasi baru serta penurunan prestasi belajar. Tujuan. Mengetahui pengaruh aktivitas fisik terhadap kapasitas memori kerja murid SMA Don Bosco III. Metode. Penelitian metode analitik dengan pendekatan potong lintang pada 113 murid SMA Don Bosco III, Bekasi, pada 18 – 20 Juli 2016. Penelitian dilakukan dengan menggunakan kuesioner demografi, kuesioner skrining gangguan mental dan penyakit kronis, Physical Acitivity Questionnaire of Adolescent (PAQ-A dan Operation Span (O-SPAN. Analisis data dengan univariat dan bivariat menggunakan uji korelasi Spearman. Hasil. Terdapat 113 murid SMA Don Bosco III dengan kisaran usia 14 – 17 tahun, usia terbanyak 15 tahun (47.8%, laki-laki 61,1%, murid kelas X 44.2%. Mayoritas responden memiliki aktivitas fisik “kurang baik” dan rerata memori kerja 6,16. Analisis Spearman menunjukkan terdapat hubungan bermakna (p<0,05 antara aktivitas fisik terhadap memori kerja dengan korelasi positif lemah (r=0,384. Kesimpulan. Terdapat korelasi positif antara aktivitas fisik dan memori kerja, aktivitas fisik yang semakin tinggi cenderung akan meningkatkan memori kerja.

Preparation, characterization and thermal properties of styrene maleic anhydride copolymer (SMA)/fatty acid composites as form stable phase change materials

International Nuclear Information System (INIS)

Sari, Ahmet; Alkan, Cemil; Karaipekli, Ali; Onal, Adem

2008-01-01

Fatty acids such as stearic acid (SA), palmitic acid (PA), myristic acid (MA) and lauric acid (LA) are promising phase change materials (PCMs) for latent heat thermal energy storage (LHTES) applications, but high cost is the major drawback of them, limiting their utility area in thermal energy storage. The use of fatty acids as form stable PCMs will increase their feasibilities in practical applications due to the reduced cost of the LHTES system. In this regard, a series of styrene maleic anhydride copolymer (SMA)/fatty acid composites, SMA/SA, SMA/PA, SMA/MA, and SMA/LA, were prepared as form stable PCMs by encapsulation of fatty acids into the SMA, which acts as a supporting material. The encapsulation ratio of fatty acids was as much as 85 wt.% and no leakage of fatty acid was observed even when the temperature of the form stable PCM was over the melting point of the fatty acid in the composite. The prepared form stable composite PCMs were characterized using optic microscopy (OM), viscosimetry and Fourier transform infrared (FT-IR) spectroscopy methods, and the results showed that the SMA was physically and chemically compatible with the fatty acids. In addition, the thermal characteristics such as melting and freezing temperatures and latent heats of the form stable composite PCMs were measured by using the differential scanning calorimetry (DSC) technique, which indicated they had good thermal properties. On the basis of all the results, it was concluded that form stable SMA/fatty acid composite PCMs had important potential for practical LHTES applications such as under floor space heating of buildings and passive solar space heating of buildings by using wallboard, plasterboard or floors impregnated with a form stable PCM due to their satisfying thermal properties, easy preparation in desired dimensions, direct usability without needing additional encapsulation thereby eliminating the thermal resistance caused by the shell and, thus, reducing the cost of

Pengembangan Instrumen Ranah Kognitif pada Pokok Bahasan Fluida Statis SMA/MA

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Mukarramah Mustari

2016-04-01

Full Text Available This study aims to: 1 Develop Instrument Domains Cognitive at Static Fluid material in SMA / MA, 2 determine the validity of the instrument of cognitive tests on the static fluid material, 3 determine the reliability of cognitive principal static fluid discussion, 4 determine the level of difficulty of the cognitive tests on the static fluid material, 5 determine distinguishing cognitive test on static fluid material. The result products include cognitive aspects such instruments multiple choice tests and essay tests. Instrument developed on cognitive aspects in the form of multiple choice tests and a description to the extent of competence Bloom C1 to C6 on the material of Static Fluid. The Design of this study is used the development procedure Reasearch and Depelopment (R & D from Borg and Gall adopted by Sugiono ie; up to the stage seven form consisting of: the potential and problems, data collection, product design, design validation, design revisions, product trials, product revision. The data collecting is obtained from the results of expert validation instrument, the response of teachers, and product trials, and then analyzed by quantitative descriptive. The results of the analysis of the development of the instrument can be concluded that the cognitive instruments on the material of static fluid SMA / MA is excellent to be used by teachers in the assessment of competence of learners. Penelitian Pengembangan Instrumen Ranah Kognitif pada Pokok Bahasan Fluida Statis SMA/MA Ini dilakukan bertujuan;1 mengembangkan Instrumen Ranah Kognitif pada Pokok Bahasan Fluida Statis SMA/MA, 2 mengetahui validitas instrumen tes kognitif pokok bahasan fluida statis, 3 mengetahui reliabilitas kognitif pokok bahasan fluida statis, 4 mengetahui tingkat kesukaran tes kognitif pokok bahasan fluida statis, 5 mengetahui daya pembeda tes kognitif pada pokok bahasan fluida statis. Produk yang dihasilkan meliputi instrumen aspek kognitif berupa

TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.

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Shijing Luo

2009-12-01

Full Text Available Female reproductive cessation is one of the earliest age-related declines humans experience, occurring in mid-adulthood. Similarly, Caenorhabditis elegans' reproductive span is short relative to its total life span, with reproduction ceasing about a third into its 15-20 day adulthood. All of the known mutations and treatments that extend C. elegans' reproductive period also regulate longevity, suggesting that reproductive span is normally linked to life span. C. elegans has two canonical TGF-beta signaling pathways. We recently found that the TGF-beta Dauer pathway regulates longevity through the Insulin/IGF-1 Signaling (IIS pathway; here we show that this pathway has a moderate effect on reproductive span. By contrast, TGF-beta Sma/Mab signaling mutants exhibit a substantially extended reproductive period, more than doubling reproductive span in some cases. Sma/Mab mutations extend reproductive span disproportionately to life span and act independently of known regulators of somatic aging, such as Insulin/IGF-1 Signaling and Dietary Restriction. This is the first discovery of a pathway that regulates reproductive span independently of longevity and the first identification of the TGF-beta Sma/Mab pathway as a regulator of reproductive aging. Our results suggest that longevity and reproductive span regulation can be uncoupled, although they appear to normally be linked through regulatory pathways.

Experimental multiphysical characterization of an SMA driven, camber morphing owl wing section

Science.gov (United States)

Stroud, Hannah R.; Leal, Pedro B. C.; Hartl, Darren J.

2018-03-01

In the context of aerospace engineering, morphing structures are useful in their ability to change the outer mold line (OML) while improving or maintaining certain aerodynamic performance metrics. Skin-based morphing is of particular interest in that it minimizes installation volume. Shape memory alloys (SMAs) have a high force to volume ratio that makes them a suitable choice for skin-based morphing. Because the thermomechanical properties of SMAs are coupled, strain can be generated via a temperature variation; this phenomenon is used as the actuation method. Therefore, it is necessary to determine the interaction of the system not only with aerodynamic loads, but with thermal loads as well. This paper describes the wind tunnel testing and in situ thermomechanical analysis of an SMA actuated, avian inspired morphing wing. The morphing wing is embedded with two SMA composite actuators and consists of a foam core enveloped in a fiberglass-epoxy composite. As the SMA wire is heated, the actuator contracts, morphing the wing from the original owl OML to a highly cambered, high lift OML. Configuration characteristics are analyzed in situ using simultaneous three dimensional digital image correlation (DIC) and infrared thermography, thereby coupling strain and thermal measurements. This method of testing allows for the nonintrusive, multiphysical data acquisition of each actuator separately and the system as a whole.

Implementasi Sistem Informasi Akademik Menggunakan Aplikasi Jibas pada SMA Negeri 9 Padang

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Ricky Akbar

2015-10-01

Full Text Available SMA Negeri 9 Padang is one of the institutions engaged in the field of education, which requires the design of software to manage and run all school activities, one of which is the Academic Information System (SIA. SIA currently in SMA 9 Padang yet well integrated, so it still has many shortcomings in meeting the needs of the school or institution, in particular to deal with academic problems. Therefore, it needs to be implemented Academic Information System that can overcome the various shortcomings earlier. Implementation of this application starts with a preliminary study. Activities, the introduction of the school as a whole with interviews and observations, identify business processes academically at school is running and then make the proposed system as terkomputerisasinya, which is described by using the tools of Business Process Model Notation (BPMN, as well as the depiction of a working model of the system to be applied using use case diagram. The next stage is to study the literature of various books and journals to find the theoretical basis and related research. Then selecting software for SIA School, after the configuration and customization of the software modules, and the latter carry out the implementation and testing. These results indicate that the software SIA Schools that have been selected and applied that JIBAS applications, which can solve the problems on SMA Negeri 9 Padang

Identification of candidate regions for a novel Usher syndrome type II locus.

Science.gov (United States)

Ben Rebeh, Imen; Benzina, Zeineb; Dhouib, Houria; Hadjamor, Imen; Amyere, Mustapha; Ayadi, Leila; Turki, Khalil; Hammami, Bouthaina; Kmiha, Noureddine; Kammoun, Hassen; Hakim, Bochra; Charfedine, Ilhem; Vikkula, Miikka; Ghorbel, Abdelmonem; Ayadi, Hammadi; Masmoudi, Saber

2008-09-19

Chronic diseases affecting the inner ear and the retina cause severe impairments to our communication systems. In more than half of the cases, Usher syndrome (USH) is the origin of these double defects. Patients with USH type II (USH2) have retinitis pigmentosa (RP) that develops during puberty, moderate to severe hearing impairment with downsloping pure-tone audiogram, and normal vestibular function. Four loci and three genes are known for USH2. In this study, we proposed to localize the gene responsible for USH2 in a consanguineous family of Tunisian origin. Affected members underwent detailed ocular and audiologic characterization. One Tunisian family with USH2 and 45 healthy controls unrelated to the family were recruited. Two affected and six unaffected family members attended our study. DNA samples of eight family members were genotyped with polymorphic markers. Two-point and multipoint LOD scores were calculated using Genehunter software v2.1. Sequencing was used to investigate candidate genes. Haplotype analysis showed no significant linkage to any known USH gene or locus. A genome-wide screen, using microsatellite markers, was performed, allowing the identification of three homozygous regions in chromosomes 2, 4, and 15. We further confirmed and refined these three regions using microsatellite and single-nucleotide polymorphisms. With recessive mode of inheritance, the highest multipoint LOD score of 1.765 was identified for the candidate regions on chromosomes 4 and 15. The chromosome 15 locus is large (55 Mb), underscoring the limited number of meioses in the consanguineous pedigree. Moreover, the linked, homozygous chromosome 15q alleles, unlike those of the chromosome 2 and 4 loci, are infrequent in the local population. Thus, the data strongly suggest that the novel locus for USH2 is likely to reside on 15q. Our data provide a basis for the localization and the identification of a novel gene implicated in USH2, most likely localized on 15q.

NEW YOUNG STAR CANDIDATES IN THE TAURUS-AURIGA REGION AS SELECTED FROM THE WIDE-FIELD INFRARED SURVEY EXPLORER

International Nuclear Information System (INIS)

Rebull, L. M.; Padgett, D. L.; Noriega-Crespo, A.

2011-01-01

The Taurus Molecular Cloud subtends a large solid angle on the sky, in excess of 250 deg 2 . The search for legitimate Taurus members to date has been limited by sky coverage as well as the challenge of distinguishing members from field interlopers. The Wide-field Infrared Survey Explorer has recently observed the entire sky, and we take advantage of the opportunity to search for young stellar object (YSO) candidate Taurus members from a ∼260 deg 2 region designed to encompass previously identified Taurus members. We use near- and mid-infrared colors to select objects with apparent infrared excesses and incorporate other catalogs of ancillary data to present a list of rediscovered Taurus YSOs with infrared excesses (taken to be due to circumstellar disks), a list of rejected YSO candidates (largely galaxies), and a list of 94 surviving candidate new YSO-like Taurus members. There is likely to be contamination lingering in this candidate list, and follow-up spectra are warranted.

MEDIA FOTO UNTUK MENINGKATKAN KETERAMPILAN MENULIS DESKRIPSI SISWA SMA NEGERI 2 KEBUMEN

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Rina Tri Indrianingrum

2015-05-01

Full Text Available Penelitian ini bertujuan untuk menjelaskan meningkatnya keterampilan menulis deskripsi berbahasa Jawa siswa kelas X SMA N 2 Kebumen dengan menggunakan pendekatan proses dan media foto. Penelitian ini merupakan penelitian tindakan kelas atau classroom action research. Desain yang digunakan dalam penelitian ini adalah desain penelitian tindakan Kemmis dan Taggart. Penelitian ini dilaksanakan dua siklus. Subjek penelitian ini adalah siswa kelas X2 SMA Negeri 2 Kebumen tahun pelajaran 2011/2012 yang berjumlah 32 siswa. Pengumpulan data dilakukan dengan menggunakan observasi, catatan lapangan dan tes. Validitas yang digunakan adalah validitas demo-krasi, validitas proses dan validitas dialogis. Teknik yang digunakan untuk menganalisis data dalam penelitian tindakan ini adalah deskriptif. Hasil penelitian menunjukkan (1 siswa dapat menemukan ide lebih cepat, (2 siswa dapat membuat kerangka karangan, (3 siswa dapat mengembangkan kerang-ka karangan, (4 siswa dapat berpikir sistematis, (5 siswa semakin antusiasnya dalam mengikuti pembelajaran menulis karangan, (6 siswa paham melakukan proses mengarang. _________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________ PHOTOGRAPH MEDIA TO IMPROVE THE DESCRIPTION WRITING SKILL OF THE STUDENTS AT SMA NEGERI 2 KEBUMEN   Abstract This research is aimed to describe and to explain the improvement in the description writing skill of the tenth grade students at SMA N 2 Kebumen by using  approach process and photography media. This research is classroom action research or classroom action research. The design used in this research was action research design by Kemmis and Taggart. The subject of the research was X2 class students at SMA Negeri 2 Kebumen in the academic year of 2011/2012, consisted of 32

Experimental study on tunnel lining joints temporarily strengthened by SMA bolts

International Nuclear Information System (INIS)

Wu, Bo; Ou, Yunlong

2014-01-01

Shield tunnels have been widely used in city metros all over the world. During the long-term period of the metro operation, the joints of shield tunnel’s neighboring segments may degrade due to some environmental factors, leading to the increasing of the joint opening and some resulting adverse consequences. In this paper, a temporary strengthening method by using shape memory alloy (SMA) bolts is proposed and experimentally studied for the joints of neighboring segments, and a revised electric heating method which suits with the strengthening method is presented and experimentally validated for the SMA bolts. The purpose of the proposed temporary strengthening method is to create favorable conditions for the following permanent strengthening. Test results show that: (a) for the joints of shield tunnel’s neighboring segments, the strengthening method can effectively reduce the joint opening, joint deflection, concrete strain in joint’s compression zone, and strain of joint’s steel bolts; (b) the revised electric heating method can be used to heat the SMA rod to a temperature higher than the SMA’s austenite finish temperature quickly, and the average heating rate related to Type 2 inner resistance element is larger than that related to Type 1 inner resistance element; and (c) the reduction percentages of the joint opening increment, joint deflection, concrete strain in joint’s compression zone, and strain of joint’s steel bolts for Specimen I are all larger than those for Specimen II, implying that the less the joint opening is, the more significant the strengthening effect is. (paper)

PENGARUH PENDEKATAN KONTEKSTUAL TERHADAP HASIL BELAJAR BIOLOGI SISWA SMA

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Irwandi -

2013-05-01

Full Text Available Abstract: Contextual Teaching and Learning and Biology Learning Achievement among Senior High School Students. This quasi experimental study was designed to explain the effects of inquiry learning of Contextual Teaching and Learning (CTL, learning community of CTL, and entry behavior on Biology learning achievement of senior high school students of Bengkulu. The subjects were randomly selected from year-10 classes of eight schools and assigned to eight experimental classes. The study shows that: (1 the inquiry learning of CTL has no effect on the students’ cognitive learning achievement; (2 the learning community, particularly the extended one, of CTL  contributes to the students’ cognitive learning achievement; and (3 the students’ entry behavior did not affect their cognitive learning achievement when the students learned through inquiry process of CTL. Abstrak: Pengaruh Pendekatan Kontekstual terhadap Hasil Belajar Biologi Siswa SMA. Penelitian ini bertujuan untuk mengetahui: 1 pengaruh pendekatan kontekstual melalui strategi inkuiri terhadap hasil belajar kognitif siswa; 2 pengaruh pendekatan kontekstual melalui masyarakat belajar terhadap hasil belajar kognitif siswa; dan 3 pengaruh kemampuan awal siswa terhadap hasil belajar kognitifnya, pada pembela­jaran kontekstual melalui strategi inkuiri tingkat 1 dan 2. Penelitian dilakukan terhadap siswa-siswa pada pembelajaran biologi di 8 buah kelas X, masing-masing dari salah satu SMAN Bengkulu yang dipilih secara random. Penelitian ini menggunakan rancangan kuasi eksperimen Pretest-posttest Nonequivalent Control Group Design dengan rancangan penelitian faktorial 2 x 2 x 2. Hasil penelitian menunjukkan bahwa 1 pendekatan kontekstual melalui strategi inkuiri, tidak berpengaruh terhadap hasil belajar kognitif siswa di SMA 2 pendekatan kontekstual melalui masyarakat belajar berpengaruh terhadap hasil belajar kognitif siswa di SMA di mana hasil belajar kognitif melalui masyarakat belajar

PENGARUH MODEL EXPERIENTIAL LEARNING TERHADAP KEMAMPUAN BERPIKIR SISWA SMA

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Mar’atus Sholihah

2016-11-01

Full Text Available The purpose of this study was to determine the effect of Experiential Learning models developed by Kolb's theory of the critical thinking skills of high school students. This study uses a quasi experiment conducted in SMA Assa'adah Gresik. The population of students of class X IS second semester of academic year 2015/2016. Samples are 2 classes that are homogeneous. Methods of data collection using test questions and the ability to think critically using observation sheet. Data were analyzed by comparing the average acquisition value of critical thinking skills with experimental class control class. Average value of the critical thinking skills using model Experiential Learning higher at 80.9 while the control class is 71.2. Based on the average it can be concluded that the learning model of Experiential Learning can improve students' critical thinking skills. This study is expected to provide information on the application and benefits of the model Experiential Learning in teaching geography and make it more meaningful for students. Tujuan dari penelitian ini adalah mengetahui pengaruh model Experiential Learning yang dikembangkan oleh teori Kolb terhadap kemampuan berpikir kritis siswa SMA. Penelitian ini menggunakan metode quasi experimen yang dilakukan di SMA Assa’adah Gresik. Populasi siswa kelas X IS semester genap tahun pelajaran 2015/2016. Sampel yang digunakan sebanyak 2 kelas yang bersifat homogen. Metode pengumpulan data menggunakan soal tes kemampuan berpikir kritis serta menggunakan lembar observasi. Data yang diperoleh kemudian dianalisis dengan membandingkan rata-rata perolehan nilai kemampuan berpikir kritis kelas kontrol dengan kelas eksperimen. Nilai rata rata kemampuan berpikir kritis yang menggunakan model pembelajaran Experiential Learning lebih tinggi, yaitu sebesar 80,9, sedangkan kelas kontrol sebesar 71,2. Berdasarkan nilai rata-rata tersebut dapat disimpulkan bahwa model pembelajaran Experiential Learning dapat

Evaluation of Fatigue Life of CRM-Reinforced SMA and Its Relationship to Dynamic Stiffness

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Nuha Salim Mashaan

2014-01-01

Full Text Available Fatigue cracking is an essential problem of asphalt concrete that contributes to pavement damage. Although stone matrix asphalt (SMA has significantly provided resistance to rutting failure, its resistance to fatigue failure is yet to be fully addressed. The aim of this study is to evaluate the effect of crumb rubber modifier (CRM on stiffness and fatigue properties of SMA mixtures at optimum binder content, using four different modification levels, namely, 6%, 8%, 10%, and 12% CRM by weight of the bitumen. The testing undertaken on the asphalt mix comprises the dynamic stiffness (indirect tensile test, dynamic creep (repeated load creep, and fatigue test (indirect tensile fatigue test at temperature of 25°C. The indirect tensile fatigue test was conducted at three different stress levels (200, 300, and 400 kPa. Experimental results indicate that CRM-reinforced SMA mixtures exhibit significantly higher fatigue life compared to the mixtures without CRM. Further, higher correlation coefficient was obtained between the fatigue life and resilient modulus as compared to permanent strain; thus resilient modulus might be a more reliable indicator in evaluating the fatigue life of asphalt mixture.

Evaluation of fatigue life of CRM-reinforced SMA and its relationship to dynamic stiffness.

Science.gov (United States)

Mashaan, Nuha Salim; Karim, Mohamed Rehan; Abdel Aziz, Mahrez; Ibrahim, Mohd Rasdan; Katman, Herda Yati; Koting, Suhana

2014-01-01

Fatigue cracking is an essential problem of asphalt concrete that contributes to pavement damage. Although stone matrix asphalt (SMA) has significantly provided resistance to rutting failure, its resistance to fatigue failure is yet to be fully addressed. The aim of this study is to evaluate the effect of crumb rubber modifier (CRM) on stiffness and fatigue properties of SMA mixtures at optimum binder content, using four different modification levels, namely, 6%, 8%, 10%, and 12% CRM by weight of the bitumen. The testing undertaken on the asphalt mix comprises the dynamic stiffness (indirect tensile test), dynamic creep (repeated load creep), and fatigue test (indirect tensile fatigue test) at temperature of 25°C. The indirect tensile fatigue test was conducted at three different stress levels (200, 300, and 400 kPa). Experimental results indicate that CRM-reinforced SMA mixtures exhibit significantly higher fatigue life compared to the mixtures without CRM. Further, higher correlation coefficient was obtained between the fatigue life and resilient modulus as compared to permanent strain; thus resilient modulus might be a more reliable indicator in evaluating the fatigue life of asphalt mixture.

PENGARUH KOMPETENSI SUMBER DAYA MANUSIA TERHADAP KINERJA PEGAWAI DAN GURU PADA SMA SARIBUANA MAKASSAR

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Novita _

2017-08-01

Full Text Available NOVITA. 2017.Essay . The Influence of Human Resource Competency on Employee and Teacher Performance at SMA SARIBUANA Makassar South Sulawesi Province.Guided by Indrayani Nur, S. Pd SE., M.Si. An employee is an individual who works for an employer, by contract or agreement whether in writing or in writing, to carry out a job or occupation in a particular activity by obtaining compensation paid under a specified period. This study aims to analyze the influence of human resource competencies on the performance of employees and teachers in SMA SARIBUANA Makassar. Analyzer used is multiple linear regression. Respondents of this research are employees and teachers of SMA Saribuana Makassar. The results of the analysis show that knowledge, mastery of science of technology and motivation affect the improvement of employee and teacher performance From the ANOVA or F test, the significant number (Sig (0,000 is below 0.05 and the Fcount is 19.614 where the Fcount is greater than the Ftable of 3.35. Thus, Fcount > Ftable then this result indicates that the independent variable (knowledge, mastery of technology science, motivation influence together to the dependent variable (employee and teacher performance.

MENINGKATKAN KEMAMPUAN BERPIKIR KREATIF MATEMATIS SISWA SMA MELALUI PEMBELAJARAN OPEN ENDED PADA MATERI SPLDV

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Firdaus Firdaus

2016-02-01

Penelitian ini bertujuan untuk mendeskripsikan kemampuan berpikir kreatif matematis siswa SMA melalui pembelajaran open ended problem materi SPLDV. Jenis penelitian ini, yaitu deskriptif kualitatif. Subjeknya adalah siswa kelas X.2 SMA Negeri 1 Woja Dompu. Tahap pembelajaran dalam penelitian ini adalah (1 Orientasi, (2 pembekalan materi, (3 penyajian dan pengerjaan soal open ended, (4 presentasi, (5 kesimpulan. Kemampuan berpikir kreatif matematis siswa meliputi: (a fluency, kemampuan siswa lancar dalam memberikan jawaban benar, (b flexibility, kemampuan siswa dalam menggunakan berbagai cara penyelesaian masalah, (c novelty, kemampuan siswa dalam memberikan jawaban yang baru dan berbeda dengan siswa lain. Penelitian ini hasilnya, bahwa siswa mempunyai kemampuan berpikir kreatif matematis.

Analysis of the modifying influence of Plastin 3 (PLS3) on Spinal Muscular Atrophy (SMA) by generation of transgenic mouse models

OpenAIRE

Ackermann, Bastian

2011-01-01

Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by the loss of α-motor neurons in the ventral horn of the spinal cord. Depending on the severity, the clinical spectrum of SMA ranges from early infant death to normal adult life with only mild muscle weakness. To date, no cure is available. SMA is caused by the homozygous loss of the survival motor neuron gene 1 (SMN1). Besides SMN1, another nearly identical copy of the gene is present in the human genome, thus called...

Dynamical analysis and development of a biologically inspired SMA caterpillar robot.

Science.gov (United States)

Daily-Diamond, Christopher A; Novelia, Alyssa; O'Reilly, Oliver M

2017-09-26

With the goal of robustly designing and fabricating a soft robot based on a caterpillar featuring shape memory alloy (SMA) actuators, analytical and numerical models for a soft robot were created based on the forward crawling motion of the Manduca sexta caterpillar. The analytical model features a rod theory and the mechanics of undulation were analyzed using a motion pattern based on the 'Witch of Agnesi' curve. Complementing these models, experiments on a SMA actuator sample were performed in order to determine its flexural rigidity and curvature as a function of the actuation voltage. A series of these actuators can be modeled as a system of rigid bodies connected by torsional springs. As these bodies are actuated according to the motion pattern based on the individual caterpillar segments, ground contact forces are calculated and analyzed to determine the requirements of successful forward locomotion. The energetics of the analytical and numerical models are then compared and discussed.

Organization and annotation of the Xcat critical region: elimination of seven positional candidate genes.

Science.gov (United States)

Huang, Kristen M; Geunes-Boyer, Scarlett; Wu, Sufen; Dutra, Amalia; Favor, Jack; Stambolian, Dwight

2004-05-01

Xcat mice display X-linked congenital cataracts and are a mouse model for the human X-linked cataract disease Nance Horan syndrome (NHS). The genetic defect in Xcat mice and NHS patients is not known. We isolated and sequenced a BAC contig representing a portion of the Xcat critical region. We combined our sequencing data with the most recent mouse sequence assemblies from both Celera and public databases. The sequence of the 2.2-Mb Xcat critical region was then analyzed for potential Xcat candidate genes. The coding regions of the seven known genes within this area (Rai2, Rbbp7, Ctps2, Calb3, Grpr, Reps2, and Syap1) were sequenced in Xcat mice and no mutations were detected. The expression of Rai2 was quantitatively identical in wild-type and Xcat mutant eyes. These results indicate that the Xcat mutation is within a novel, undiscovered gene.

MODEL EVALUASI INTERNAL KOMPETENSI GURU BAHASA INGGRIS (MODEL_EIKGBI SMA

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Sahraini Sahraini

2015-10-01

Full Text Available Studi ini bertujuan untuk: (1 mengembangkan model evaluasi kompetensi guru bahasa Inggris SMA yang dapat digunakan untuk mengidentifikasi kelebihan dan kekurangan guru dalam proses pemelajaran dan (2 mengetahui efektivitas implementasi evaluasi internal kompetensi guru bahasa Inggris SMA. Studi ini menggunakan metode penelitian dan pengembangan yang dikembangkan oleh Borg & Gall (1983, p.775. Subjek penelitian berjumlah 17 guru yang berasal dari 7 SMA di Sulawesi Selatan. Konstruk instrumen terdiri atas instrumen untuk mengevaluasi kompetensi guru bahasa Inggris dalam merencanakan pemelajaran, instrumen untuk mengevaluasi kompetensi guru dalam melaksanaan proses pemelajaran, dan instrumen untuk mengevaluai kompetensi guru dalam mengevaluasi hasil proses pemelajaran. Hasil penelitian menunjukkan bahwa instrumen yang dikembangkan dapat digunakan untuk mengevaluasi kompetensi guru bahasa Inggris. Untuk mengetahui sejauh mana tingkat efektivitas Model Evaluasi Internal Kompetensi Guru Bahasa Inggris SMA, model ini kemudian dievaluasi oleh teman sejawat guru bahasa Inggris dan guru bahasa Inggris itu sendiri. Mereka menyimpulkan bahwa komponen dari model tersebut adalah komprehensip, praktis, ekonomis, dan telah didukung oleh instrumen yang valid dan reliabel. Kata kunci: evaluasi internal, model evaluasi, kompetensi guru   INTERNAL EVALUATION MODEL OF ENGLISH TEACHERS’ COMPETENCY (IEMET FOR SENIOR HIGH SCHOOL Abstract High School that can be used to identify the teacher’s strengths and weaknesses in learning and teaching processes and (2 find out the implementation effectiveness of the Internal Evaluation Model of English Teachers’ Competency for Senior High School. This study used research & development methods by following the pattern of phases developed by Borg & Gall (1983, p.775.  The subjects of this study were seventeen English teachers from seven Senior High Schools in South Sulawesi. The constructs of instruments consist of the

Pengembangan Modul Fisika Pokok Bahasan Hukum Newton bagi Anak Berkebutuhan Khusus (Tunanetra Di Kelas Inklusi SMA/MA Kelas X

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Fitriany Yudistia R

2014-04-01

Full Text Available Siswa tunanetra SMA Muhammadiyah 4 Yogyakarta, MAN Maguwoharjo dan SMAN 1 Sewon belum memiliki sumber belajar mandiri berupa modul Braille khususnya pada materi Hukum Newton. Berdasarkan kenyataan ini maka dibutuhkan sebuah sumber belajar yang didesain khusus bagi siswa tunanetra di kelas Inklusi yakni modul Braille pada pokok bahasan Hukum Newton.Telah dilakukan penelitian yang bertujuan untuk: (1 mengembangkan modul fisika pokok bahasan Hukum Newton untuk siswa tunanetra SMA/MA kelas X sebagai sumber belajar mandiri, (2 mengetahui kualitas modul fisika Braille materi Hukum Newton untuk siswa tunanetra SMA/MA kelas X, (3 mengetahui respon siswa terhadap modul fisika Braille yang telah dikembangkan.Penelitian ini merupakan penelitian R & D dengan model prosedural yang mengadaptasi dari pengembangan perangkat model 4-D, yakni Define, Design, Develop, and Disseminate. Instrumen penelitian berupa angket kualitas modul yaitu menggunakan skala Likert yang dibuat dalam bentuk checklist. Instrumen untuk siswa berupa angket respon siswa yaitu menggunakan skala Guttman yang dibuat dalam bentuk checklist. Modul dinilai kualitasnya oleh 3 ahli materi, 1 ahli media, dan 2 guru fisika SMA/MA. Kelayakan modul berdasarkan respon siswa pada uji coba terbatas sebanyak 2 siswa dan uji coba luas sebanyak 8 siswa.Hasil penelitian berdasarkan penilaian dari ahli materi, ahli media dan guru fisika SMA/MA modul memiliki kategori sangat baik (SB. Persentase keidealan menurut ahli materi adalah 87,88%; persentase keidealan menurut ahli media adalah 90,00% dan persentase keidealan menurut guru Fisika SMA/MA adalah 75,00%. Respon siswa terhadap modul fisika Braille pada uji coba terbatas diperoleh persentase 97,22%; sedangkan pada uji coba luas diperoleh persentase 89,58%. Hasil penelitian ini menunjukkan bahwa modul layak dijadikan sebagai salah satu sumber belajar mandiri bagi siswa tunanetra.

PENGARUH DARI NEPTUNE KRILL OIL PADA MANAJEMEN DISMINOREA PADA REMAJA PUTRI KELAS X DI SMA NEGERI 1 PRINGSEWU

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Indri Retno Palupi

2016-12-01

Full Text Available Hasil survei Perkumpulan Keluarga Berencana Indonesia (PKBI cabang Bandar Lampung tahun 2014, dismenorhea  menempati urutan pertama keluhan yang sering dialami wanita, sebesar 65,3% selain siklus menstruasi yang tidak teratur. Prevalensi dismenorhea  lebih tinggi pada kelompok usia remaja 10-20 tahun sebesar 71,4%. Tujuan penelitian ini diketahui pengaruh dari neptune krill oil  pada manajemen disminorea pada remaja putri kelas X di SMA Negeri 1 Pringsewu tahun 2016. Jenis penelitian ini adalah kuantitatif dengan menggunakan rancangan desain  eksperimen dengan menggunakan pendekatan one group pre and post test. Populasi dalam penelitian ini adalah seluruh remaja putri kelas X di SMA Negeri 1 Pringsewu yang berjumlah 193 orang, sampel dalam penelitian ini berjumlah 30 orang. Teknik sampling dalam penelitian ini menggunakan teknik accidental. Analisis data yang digunakan dalam penelitian ini univariat dan bivariat dengan uji t-test.Tingkat nyeri dismenorhea  sebelum diberi Neptune krill oil  pada siswi kelas X SMA Negeri 1 Pringsewu memiliki rata-rata tingkatan nyeri yaitu 8,190 (pada skala 1-15, Tingkat nyeri dismenorhea  setelah diberi Neptune krill oil  pada siswi kelas X SMA Negeri 1 Pringsewu memiliki Rata-rata tingkat nyeri yaitu 4,747 (pada skala 1-15. Ada pengaruh pemberian Neptune krill oil  terhadap intensitas nyeri dismenorhea  pada siswi kelas X SMA Negeri 1 Pringsewu Tahun 2016 (p-value=0,000. Diharapkan remaja putri dapat mengetahui bahwa salah satu cara untuk mengurangi nyeri dismenorhea  adalah dengan mengkonsumsi Neptune krill oil. Sehingga remaja putri dapat menerapkannya dirumah saat mengalami dismenorhea.

KESANTUNAN TUTURAN DIREKTIF DALAM INTERAKSI PEMBELAJARAN DI SMA

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Mardiyah Putri Astuti

2017-03-01

Full Text Available Politeness speech in learning interactions in the classroom tend to be effected through a directive speech. Assessment of form directive speech made by using a guide to the theory and analysis based on speech act theory directive Bach and Harnish. This study aims to determine the form of politeness directive in an interaction study in SMA 1 Batu. Forms directive speech in learning interactions are marked with (1 directive requests, (2 directive question, (3 directive command, (4 The prohibition directive, (5 directive licensing, and (6 the directive advice. The results of the analysis of the forms of speech directive shows that teachers do politeness predominantly through commands, prohibitions, permissions, and advice, while the shape of the directive utterances made by teachers and students to consider cultural aspects. Kesantunan tuturan dalam interaksi pembelajaran di dalam kelas cenderung dilakukan melalui bentuk tuturan direktif. Pengkajian terhadap bentuk tuturan direktif dilakukan dengan mengggunakan teori dan panduan analisis berdasarkan teori tindak tutur direktif Bach dan Harnish. Penelitian ini bertujuan untuk mengetahui bentuk kesantunan direktif dalam interaksi pembelajaran di SMA 1 Batu. Bentuk tuturan direktif dalam interaksi pembelajaran ditandai dengan (1 direktif permintaan, (2 direktif pertanyaan, (3 direktif perintah, (4 direktif larangan, (5 direktif pemberian izin, dan (6 direktif nasihat. Hasil analisis mengenai bentuk tuturan direktif menunjukkan bahwa guru melakukan kesantunan secara dominan melalui perintah, larangan, izin, dan nasihat, sedangkan bentuk tuturan direktif dilakukan oleh guru dan siswa dengan mempertimbangkan aspek budaya.

Scaling structure loads for SMA

Energy Technology Data Exchange (ETDEWEB)

Lee, Dong Won; Song, Jeong Guk; Jeon, Sang Ho; Lim, Hak Kyu; Lee, Kwang Nam [KEPCO ENC, Yongin (Korea, Republic of)

2012-10-15

When the Seismic Margin Analysis(SMA) is conducted, the new structural load generation with Seismic Margin Earthquake(SME) is the time consuming work. For the convenience, EPRI NP 6041 suggests the scaling of the structure load. The report recommend that the fixed base(rock foundation) structure designed using either constant modal damping or modal damping ratios developed for a single material damping. For these cases, the SME loads can easily and accurately be calculated by scaling the spectral accelerations of the individual modes for the new SME response spectra. EPRI NP 6041 provides two simple methodologies for the scaling structure seismic loads which are the dominant frequency scaling methodology and the mode by mode scaling methodology. Scaling of the existing analysis to develop SME loads is much easier and more efficient than performing a new analysis. This paper is intended to compare the calculating results of two different methodologies.

Scaling structure loads for SMA

International Nuclear Information System (INIS)

Lee, Dong Won; Song, Jeong Guk; Jeon, Sang Ho; Lim, Hak Kyu; Lee, Kwang Nam

2012-01-01

When the Seismic Margin Analysis(SMA) is conducted, the new structural load generation with Seismic Margin Earthquake(SME) is the time consuming work. For the convenience, EPRI NP 6041 suggests the scaling of the structure load. The report recommend that the fixed base(rock foundation) structure designed using either constant modal damping or modal damping ratios developed for a single material damping. For these cases, the SME loads can easily and accurately be calculated by scaling the spectral accelerations of the individual modes for the new SME response spectra. EPRI NP 6041 provides two simple methodologies for the scaling structure seismic loads which are the dominant frequency scaling methodology and the mode by mode scaling methodology. Scaling of the existing analysis to develop SME loads is much easier and more efficient than performing a new analysis. This paper is intended to compare the calculating results of two different methodologies

Potentiation of motor sub-networks for motor control but not working memory: Interaction of dACC and SMA revealed by resting-state directed functional connectivity

Science.gov (United States)

Diwadkar, Vaibhav A.; Asemi, Avisa; Burgess, Ashley; Chowdury, Asadur; Bressler, Steven L.

2017-01-01

The dorsal Anterior Cingulate Cortex (dACC) and the Supplementary Motor Area (SMA) are known to interact during motor coordination behavior. We previously discovered that the directional influences underlying this interaction in a visuo-motor coordination task are asymmetric, with the dACC→SMA influence being significantly greater than that in the reverse direction. To assess the specificity of this effect, here we undertook an analysis of the interaction between dACC and SMA in two distinct contexts. In addition to the motor coordination task, we also assessed these effects during a (n-back) working memory task. We applied directed functional connectivity analysis to these two task paradigms, and also to the rest condition of each paradigm, in which rest blocks were interspersed with task blocks. We report here that the previously known asymmetric interaction between dACC and SMA, with dACC→SMA dominating, was significantly larger in the motor coordination task than the memory task. Moreover the asymmetry between dACC and SMA was reversed during the rest condition of the motor coordination task, but not of the working memory task. In sum, the dACC→SMA influence was significantly greater in the motor task than the memory task condition, and the SMA→dACC influence was significantly greater in the motor rest than the memory rest condition. We interpret these results as suggesting that the potentiation of motor sub-networks during the motor rest condition supports the motor control of SMA by dACC during the active motor task condition. PMID:28278267

Advanced methods for the analysis, design, and optimization of SMA-based aerostructures

International Nuclear Information System (INIS)

Hartl, D J; Lagoudas, D C; Calkins, F T

2011-01-01

Engineers continue to apply shape memory alloys to aerospace actuation applications due to their high energy density, robust solid-state actuation, and silent and shock-free operation. Past design and development of such actuators relied on experimental trial and error and empirically derived graphical methods. Over the last two decades, however, it has been repeatedly demonstrated that existing SMA constitutive models can capture stabilized SMA transformation behaviors with sufficient accuracy. This work builds upon past successes and suggests a general framework by which predictive tools can be used to assess the responses of many possible design configurations in an automated fashion. By applying methods of design optimization, it is shown that the integrated implementation of appropriate analysis tools can guide engineers and designers to the best design configurations. A general design optimization framework is proposed for the consideration of any SMA component or assembly of such components that applies when the set of design variables includes many members. This is accomplished by relying on commercially available software and utilizing tools already well established in the design optimization community. Such tools are combined with finite element analysis (FEA) packages that consider a multitude of structural effects. The foundation of this work is a three-dimensional thermomechanical constitutive model for SMAs applicable for arbitrarily shaped bodies. A reduced-order implementation also allows computationally efficient analysis of structural components such as wires, rods, beams and shells. The use of multiple optimization schemes, the consideration of assembled components, and the accuracy of the implemented constitutive model in full and reduced-order forms are all demonstrated

Studi Kasus Tentang Siswi yang Memiliki Konsep Diri Negatif pada Kelas X SMA Mujahidin Pontianak Tahun 2017

OpenAIRE

Ningsih, Dwi Purwanti

2017-01-01

This research entitled case study about student who have negative self concept in class X SMA Mujahidin Pontianak. Common problem in this research is how effort to help student having negatif self concept in class X SMA Mujahidin Pontianak? As for the sub-problems: 1) How are the characteristics of student who have negative self concept?, 2) What psychological factors that cause student to have negative self concept?, 3) What physiological factors that cause student to have a negative self co...

Peningkatan Mutu Pendidikan SMA Muhammadiyah 2 Sidoarjo sebagai Sekolah Berkategori The Outstanding School of Muhammadiyah

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Hidayatulloh Hidayatulloh

2016-09-01

Full Text Available This article examines about improving the education quality of SMA Muhammadiyah 2 Sidoarjo as the Outstanding School of Muhammadiyah. This article reveals that the quality improvement of SMA Muhammadiyah 2 Sidoarjo was conducted through: the arrangement of school program and self evaluation, the reinforcement of vision, mission and education objective, the reinforcement of leadership and teamwork, the improvement of teachers and educators competence, the improvement learners quality input, the development of curriculum and learning, the development of school culture, the development of facilities and infrastructure, the development of community service, the cooperation of education and student exchange, the mobilization of education funding resources, the develop-ment of SIM, monitoring and evaluation, and education quality system. The management quality of SMA Muhammadiyah 2 Sidoarjo was run through input-process-output formula. The process of quality containes the process of quality planning, main process, supporting process, dan quality improvement process. Factors supporting the quality improvement are: Muhammadiyah’s popular name, the doctrine of education quality improvement, the leadership of TORSIE paradigm, the school academicians’ spirit of gaining achievement, the synergy of school academicians, the appropriate facilities, and the supports of all stakeholders.

Kondisi Stres Akademik Siswa SMA Negeri di Kota Padang

OpenAIRE

Taufik Taufik; Ifdil Ifdil

2014-01-01

This research conduct base from increasing the National Examination standards from recent years, and overload student’s learning activity in Senior High School (SMA). These conditions as triggers stress students, from a long time, its influence on their learning. Based that, the research is to identify level of student academic stress, and differences base gender, and school location. This research use Cluster Random Sampling. Samples are grouped into 3 (three), that’s school is located in do...

SMA foil-based elastocaloric cooling: from material behavior to device engineering

Science.gov (United States)

Bruederlin, F.; Ossmer, H.; Wendler, F.; Miyazaki, S.; Kohl, M.

2017-10-01

The elastocaloric effect associated with the stress-induced first order phase transformation in pseudoelastic shape memory alloy (SMA) films and foils is of special interest for cooling applications on a miniature scale enabling fast heat transfer and high cycling frequencies as well as tunable transformation temperatures. The focus is on TiNi-based materials having the potential to meet the various challenges associated with elastocaloric cooling including large adiabatic temperature change and ultra-low fatigue. The evolution of strain and temperature bands during tensile load cycling is investigated with respect to strain and strain-rate by in situ digital image correlation and infrared thermography with a spatial resolution in the order of 25 µm. Major design issues and challenges in fabrication of SMA film-based elastocaloric cooling devices are discussed including the efficiency of heat transfer as well as force recovery to enhance the coefficient of performance (COP) on the system level. Advanced demonstrators show a temperature span of 13 °C after 30 s, while the COP of the overall device reaches almost 10% of Carnot efficiency.

THE SPITZER SURVEY OF INTERSTELLAR CLOUDS IN THE GOULD BELT. III. A MULTI-WAVELENGTH VIEW OF CORONA AUSTRALIS

International Nuclear Information System (INIS)

Peterson, Dawn E.; Bourke, Tyler L.; Forbrich, Jan; Patten, Brian M.; Caratti o Garatti, Alessio; Gutermuth, Robert A.; Joergensen, Jes K.; Allen, Lori E.; Dunham, Michael M.; Harvey, Paul M.; Evans, Neal J.; MerIn, Bruno; Chapman, Nicholas L.; Cieza, Lucas A.; Huard, Tracy L.; Knez, Claudia; Prager, Brian

2011-01-01

We present Spitzer Space Telescope IRAC and MIPS observations of a 0.85 deg 2 field including the Corona Australis (CrA) star-forming region. At a distance of 130 pc, CrA is one of the closest regions known to be actively forming stars, particularly within its embedded association, the Coronet. Using the Spitzer data, we identify 51 young stellar objects (YSOs) in CrA which include sources in the well-studied Coronet cluster as well as sources distributed throughout the molecular cloud. Twelve of the YSOs discussed are new candidates, one of which is located in the Coronet. Known YSOs retrieved from the literature are also added to the list, and a total of 116 candidate YSOs in CrA are compiled. Based on these YSO candidates, the star formation rate is computed to be 12 M sun Myr -1 , similar to that of the Lupus clouds. A clustering analysis was also performed, finding that the main cluster core, consisting of 68 members, is elongated (having an aspect ratio of 2.36), with a circular radius of 0.59 pc and mean surface density of 150 pc -2 . In addition, we analyze outflows and jets in CrA by means of new CO and H 2 data. We present 1.3 mm interferometric continuum observations made with the Submillimeter Array (SMA) covering R CrA, IRS 5, IRS 7, and IRAS 18595-3712 (IRAS 32). We also present multi-epoch H 2 maps and detect jets and outflows, study their proper motions, and identify exciting sources. The Spitzer and ISAAC/VLT observations of IRAS 32 show a bipolar precessing jet, which drives a CO(2-1) outflow detected in the SMA observations. There is also clear evidence for a parsec-scale precessing outflow, which is east-west oriented and originates in the SMA 2 region and likely driven by SMA 2 or IRS 7A.

Novel candidate genes and regions for childhood apraxia of speech identified by array comparative genomic hybridization.

Science.gov (United States)

Laffin, Jennifer J S; Raca, Gordana; Jackson, Craig A; Strand, Edythe A; Jakielski, Kathy J; Shriberg, Lawrence D

2012-11-01

The goal of this study was to identify new candidate genes and genomic copy-number variations associated with a rare, severe, and persistent speech disorder termed childhood apraxia of speech. Childhood apraxia of speech is the speech disorder segregating with a mutation in FOXP2 in a multigenerational London pedigree widely studied for its role in the development of speech-language in humans. A total of 24 participants who were suspected to have childhood apraxia of speech were assessed using a comprehensive protocol that samples speech in challenging contexts. All participants met clinical-research criteria for childhood apraxia of speech. Array comparative genomic hybridization analyses were completed using a customized 385K Nimblegen array (Roche Nimblegen, Madison, WI) with increased coverage of genes and regions previously associated with childhood apraxia of speech. A total of 16 copy-number variations with potential consequences for speech-language development were detected in 12 or half of the 24 participants. The copy-number variations occurred on 10 chromosomes, 3 of which had two to four candidate regions. Several participants were identified with copy-number variations in two to three regions. In addition, one participant had a heterozygous FOXP2 mutation and a copy-number variation on chromosome 2, and one participant had a 16p11.2 microdeletion and copy-number variations on chromosomes 13 and 14. Findings support the likelihood of heterogeneous genomic pathways associated with childhood apraxia of speech.

Design optimization and uncertainty analysis of SMA morphing structures

International Nuclear Information System (INIS)

Oehler, S D; Hartl, D J; Lopez, R; Malak, R J; Lagoudas, D C

2012-01-01

The continuing implementation of shape memory alloys (SMAs) as lightweight solid-state actuators in morphing structures has now motivated research into finding optimized designs for use in aerospace control systems. This work proposes methods that use iterative analysis techniques to determine optimized designs for morphing aerostructures and consider the impact of uncertainty in model variables on the solution. A combination of commercially available and custom coded tools is utilized. ModelCenter, a suite of optimization algorithms and simulation process management tools, is coupled with the Abaqus finite element analysis suite and a custom SMA constitutive model to assess morphing structure designs in an automated fashion. The chosen case study involves determining the optimized configuration of a morphing aerostructure assembly that includes SMA flexures. This is accomplished by altering design inputs representing the placement of active components to minimize a specified cost function. An uncertainty analysis is also conducted using design of experiment methods to determine the sensitivity of the solution to a set of uncertainty variables. This second study demonstrates the effective use of Monte Carlo techniques to simulate the variance of model variables representing the inherent uncertainty in component fabrication processes. This paper outlines the modeling tools used to execute each case study, details the procedures for constructing the optimization problem and uncertainty analysis, and highlights the results from both studies. (paper)

Experiment feedbacks in micromechanics modeling of thermomechanical behaviour of SMA polycrystals

Czech Academy of Sciences Publication Activity Database

Šittner, Petr; Novák, Václav

2004-01-01

Roč. 51, - (2004), s. 321-326 ISSN 1359-6462 R&D Projects: GA AV ČR IAA1048107; GA ČR GA202/04/2016 Institutional research plan: CEZ:AV0Z1010914 Keywords : shape memory alloys (SMA) * martensitic phase transformation * micromechanical modeling * neutron diffraction Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.112, year: 2004

EVALUASI STRATEGI BERSAING SMA KRISTEN 1 SALATIGA

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Eclesia Tehupeiory

2015-06-01

Full Text Available This study aims to evaluate the competitive strategies of SMA Kristen 1 Salatiga. The type of this study was a qualitative evaluation, through data collection by means of interviews, questionnaires, observation and documentation study. Data obtained and analyzed by an evaluation component based on Rumelt (2000 were consistency, consonance, advantage and feasibility. The results showed that: (1 Consistency evaluation of competitive strategy applied by SMA Kristen 1 Salatiga has shown consistency with the goals, values and policies of the school. (2 Consonance evaluation of competitive strategy has demonstrated suitability with the needs of society, while for competition with other schools, the school programs such as Peduli Kasih program, Sekolah Lima Hari, moving class, SMUQI Radio and multimedia extracurricular namely cinematography and photography are not appropriate. (3 Advantage evaluation of competitive strategy in the school programs such as Peduli Kasih, moving class, and Sekolah Lima Hari do not excel the resources, skills and superior positions. Other programs such as multimedia Extracurricular namely photography and cinematography is not superior to the superior position. Meanwhile, special programs such as the education expo, parenting day, career day and the Field Trip program through Live In and outdoor study do not excel in superior skills. (4 Feasibility evaluation shows that multimedia extracurricular programs have not showed the feasibility of the physical resources which involves computer supporting facilities and Wi-Fi. Suggestion to school in order to maintain the consistency that was owned, suitability to the needs of society as well as pay attention to competition with other schools also enhance the achievement of advantage and checking of IT facilities.

Design and control of a linearity-enhanced SMA actuator

International Nuclear Information System (INIS)

Son, Hyung-Min; Tak, Chul-Gon; Lee, Yun-Jung; Kang, Seok-Won; Nam, Tae-Hyun; Kim, Jae-Il

2010-01-01

For the accurate and dexterous operation of mechanical systems, continuous-type actuation, rather than on/off-type actuation, is an indispensable function. However, conventional Ti-Ni alloys present difficulties for continuous positioning control, due to their hysteretic and abruptly changing relationship between strain and temperature. Therefore, this paper proposes a new linearity-enhanced SMA actuator using a temperature-gradient annealed alloy and an inverse hysteresis controller. In comparative experiments, the proposed controller and alloy exhibit superior performance for continuous actuation.

Social/economic costs and health-related quality of life in patients with spinal muscular atrophy (SMA) in Spain.

Science.gov (United States)

López-Bastida, Julio; Peña-Longobardo, Luz María; Aranda-Reneo, Isaac; Tizzano, Eduardo; Sefton, Mark; Oliva-Moreno, Juan

2017-08-18

The aim of this study was to determine the economic burden and health-related quality of life (HRQOL) of patients with Spinal Muscular Atrophy (SMA) and their caregivers in Spain. This was a cross-sectional and retrospective study of patients diagnosed with SMA in Spain. We adopted a bottom up, prevalence approach design to study patients with SMA. The patient's caregivers completed an anonymous questionnaire regarding their socio-demographic characteristics, use of healthcare services and non-healthcare services. Costs were estimated from a societal perspective (including healthcare costs and non-healthcare costs), and health-related quality of life (HRQOL) was assessed using the EQ-5D questionnaire. The main caregivers also answered a questionnaire on their characteristics and on their HRQOL. A total of 81 caregivers of patients with different subtypes of SMA completed the questionnaire. Based on the reference unitary prices for 2014, the average annual costs per patient were € 33,721. Direct healthcare costs were € 10,882 (representing around 32.3% of the total cost) and the direct non-healthcare costs were € 22,839 (67.7% of the total cost). The mean EQ-5D social tariff score for patients was 0.16, and the mean score of the EQ-5D visual analogue scale was 54. The mean EQ-5D social tariff score for caregivers was 0.49 and their mean score on the EQ-5D visual analogue scale was 69. The results highlight the burden that SMA has in terms of costs and decreased HRQOL, not only for patients but also for their caregivers. In particular, the substantial social/economic burden is mostly attributable to the high direct non-healthcare costs.

Systematic characterisation of disease associated balanced chromosome rearrangements by FISH: cytogenetically and genetically anchored YACs identify microdeletions and candidate regions for mental retardation genes

DEFF Research Database (Denmark)

Wirth, J; Nothwang, H G; van der Maarel, S

1999-01-01

the Mendelian Cytogenetics Network (MCN), a collaborative effort of, at present, 270 cytogenetic laboratories throughout the world. In this pilot study, we have characterised 10 different MR associated chromosome regions delineating candidate regions for MR. Five of these regions are narrowed to breakpoint...

PENGARUH MODEL PEMBELAJARAN KONSTRUKTIVIS 5E TERHADAP HASIL BELAJAR DI SMA LAKSAMANA MARTADINATA

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Nazila Ramadhani

2012-06-01

sehingga thitung > ttabel. Ini berarti Ha diterima, sehingga dapat disimpulkan ada pengaruh yang signifikan penerapan model pembelajaran konstruktivis 5E terhadap hasil belajar siswa pada materi pokok Medan Magnet di kelas XII semester ganjil SMA Laksamana Martadinata T.P 2011/2012.

SMA CARNIVAL TRIAL PART II: a prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy.

Directory of Open Access Journals (Sweden)

John T Kissel

Full Text Available BACKGROUND: Multiple lines of evidence have suggested that valproic acid (VPA might benefit patients with spinal muscular atrophy (SMA. The SMA CARNIVAL TRIAL was a two part prospective trial to evaluate oral VPA and L-carnitine in SMA children. Part 1 targeted non-ambulatory children ages 2-8 in a 12 month cross over design. We report here Part 2, a twelve month prospective, open-label trial of VPA and L-carnitine in ambulatory SMA children. METHODS: This study involved 33 genetically proven type 3 SMA subjects ages 3-17 years. Subjects underwent two baseline assessments over 4-6 weeks and then were placed on VPA and L-carnitine for 12 months. Assessments were performed at baseline, 3, 6 and 12 months. Primary outcomes included safety, adverse events and the change at 6 and 12 months in motor function assessed using the Modified Hammersmith Functional Motor Scale Extend (MHFMS-Extend, timed motor tests and fine motor modules. Secondary outcomes included changes in ulnar compound muscle action potential amplitudes (CMAP, handheld dynamometry, pulmonary function, and Pediatric Quality of Life Inventory scores. RESULTS: Twenty-eight subjects completed the study. VPA and carnitine were generally well tolerated. Although adverse events occurred in 85% of subjects, they were usually mild and transient. Weight gain of 20% above body weight occurred in 17% of subjects. There was no significant change in any primary outcome at six or 12 months. Some pulmonary function measures showed improvement at one year as expected with normal growth. CMAP significantly improved suggesting a modest biologic effect not clinically meaningful. CONCLUSIONS: This study, coupled with the CARNIVAL Part 1 study, indicate that VPA is not effective in improving strength or function in SMA children. The outcomes used in this study are feasible and reliable, and can be employed in future trials in SMA. TRIAL REGSITRATION: Clinicaltrials.gov NCT00227266.

[Observation on alpha-SMA during Erigeron Breviscapus (Vant) Hand-Mazz obstructs the evolution of carcinogenesis of golden hamster cheek pouch].

Science.gov (United States)

Zhou, C T; Zhang, S L; Ding, R Y; Hua, L; Zhong, W J

2000-06-01

To observe dynamically that Erigeron Breviscapus (Vant) Hand-Mazz (HEr) affects the expression of alpha-smooth muscle actin (alpha-SMA). To discuss the probable mechanism of obstructing leukoplakia carcinogenesis of this medicine. 120 golden hamsters were randomly divided into model group (48), HEr group (48) and control group (6). HEr was applied to obstruct the evolution of carcinogenesis of golden hamster cheek pouch. Immunohistochemistry was used to detect the expression level of alpha-SMA with cheek pouch specimen that besmears DMBA in 4-9 weeks. Results were compared with model group. Vessel density dyed with alpha-SMA continuously of HEr group was 65.76 significantly higher than that of model group 42.12 (P<0.001). High classification cases in HEr group were much more than model group when cases were divided into five groups as follow: 100%, 50%, 20%, 10%, 3% (P<0.01). HEr can raise the expression level of alpha-SMA exactly during the evolution of leukoplakia carcinogenesis of golden hamster, which shows that this medicine obstructs carcinogenesis by keeping the normal physiological function of vascular myoepithelial cell and integrity of vascular basement membrane.

The complete genome of Zunongwangia profunda SM-A87 reveals its adaptation to the deep-sea environment and ecological role in sedimentary organic nitrogen degradation

Directory of Open Access Journals (Sweden)

Zhou Bai-Cheng

2010-04-01

Full Text Available Abstract Background Zunongwangia profunda SM-A87, which was isolated from deep-sea sediment, is an aerobic, gram-negative bacterium that represents a new genus of Flavobacteriaceae. This is the first sequenced genome of a deep-sea bacterium from the phylum Bacteroidetes. Results The Z. profunda SM-A87 genome has a single 5 128 187-bp circular chromosome with no extrachromosomal elements and harbors 4 653 predicted protein-coding genes. SM-A87 produces a large amount of capsular polysaccharides and possesses two polysaccharide biosynthesis gene clusters. It has a total of 130 peptidases, 61 of which have signal peptides. In addition to extracellular peptidases, SM-A87 also has various extracellular enzymes for carbohydrate, lipid and DNA degradation. These extracellular enzymes suggest that the bacterium is able to hydrolyze organic materials in the sediment, especially carbohydrates and proteinaceous organic nitrogen. There are two clustered regularly interspaced short palindromic repeats in the genome, but their spacers do not match any sequences in the public sequence databases. SM-A87 is a moderate halophile. Our protein isoelectric point analysis indicates that extracellular proteins have lower predicted isoelectric points than intracellular proteins. SM-A87 accumulates organic osmolytes in the cell, so its extracelluar proteins are more halophilic than its intracellular proteins. Conclusion Here, we present the first complete genome of a deep-sea sedimentary bacterium from the phylum Bacteroidetes. The genome analysis shows that SM-A87 has some common features of deep-sea bacteria, as well as an important capacity to hydrolyze sedimentary organic nitrogen.

Lithomorphological aspects of northern Muria region for location candidate of the NPP radioactive wastes repository

International Nuclear Information System (INIS)

Sucipta

1995-01-01

As a part of planning and construction of NPP in the northern Muria region, a location candidate of the NPP radioactive waste repository needs to be prepared. The objective of this studywas to investigate the suitability of the geomorphologic condition of the northern Muria region for the location. The geomorphologic elements were evaluated based on the geomorphologic criteria specified by the IAEA. This study was conducted through descriptive and scoring methods for the geomorphologic elements, especially the landform and the geomorphologic processes. Based on the results of the study, the study area could be classified into three classes of suitability for the location. These are three geomorphologic units of high suitability, three units of moderate suitability and four units of low suitability. By considering the total value of the geomorphologic condition suitability and the inhibiting factors of geomorphology, three high suitability units were selected, particularly in the region of Lemahabang and Genggrengan. (author). 6 refs, 7 figs

Oriented regions grouping based candidate proposal for infrared pedestrian detection

Science.gov (United States)

Wang, Jiangtao; Zhang, Jingai; Li, Huaijiang

2018-04-01

Effectively and accurately locating the positions of pedestrian candidates in image is a key task for the infrared pedestrian detection system. In this work, a novel similarity measuring metric is designed. Based on the selective search scheme, the developed similarity measuring metric is utilized to yield the possible locations for pedestrian candidate. Besides this, corresponding diversification strategies are also provided according to the characteristics of the infrared thermal imaging system. Experimental results indicate that the presented scheme can achieve more efficient outputs than the traditional selective search methodology for the infrared pedestrian detection task.

Profil Problem Emosi/ Perilaku Pada Remaja Pelajar SMP-SMA Di Kota Semarang

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Annastasia Ediati

2015-10-01

Full Text Available The aims of this study is to identify the profile of emotional/behavioral problems on adolescents students of junior and senior high school (SMP-SMA in Semarang, Central Java. The subjects comprised 568 students (grade VII and X; males and females, aged between 13-17 years. Data were collected using the Indonesian translation of the Youth Self Report (YSR. The results of data analysis showed that adolescents in the junior high school/SMP reported emotional/behavioral problems more frequently than the adolescents in the senior high school/SMA (t (566 = 2.08, p = .038, especially in terms of social relations (t (566 = 2.92, p = .004, thought problems (t (566 = 2.47, p = .014, somatic complaints (t(566 = 2.98, p = .002, rule-breaking behavior (t (566 = 6.63, p < .001, and externalizing problems (t(566 = 3,37; p = .001. Gender differences was found in the adolescents’ emotional/behavioral problems. In group of junior high school students (SMP, girls reported more emotional problems than boys (t(335 = -3.55; p < .001, particularly in anxiety/depression (t(335 = -6.51; p < .001; withdrawal (t(335 = -4.26; p < .001, somatic complaints (t(335 = -2.86; p = .004; social problems (t(335 = -3.30; p = .001, attention problems (t(335 = -2.39; p = .017; and internalizing problem (t(335 = -5.76; p < .001. In group of senior high school students (SMA, boys reported more externalizing problems (t(229 = 2.10; p = .037 and rule-breaking behavior (t(229 = 4.44; p < .001 than girls. In contrasts, girls reported more somatic complaints than boys (t(229 = -3.09; p = .001. Adolescents’ emotional/behavioral problems should gained more attention. Preventive as well as curative intervention is needed, particularly intervention that sensitive to gender and age, which also involve significant figures for adolescents (parents, school teachers, and peers.

KONTRIBUSI KONSELOR DALAM MEMBENTUK KARAKTER PESERTA DIDIK SMA

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Agung Slamet Kusmanto

2015-11-01

Full Text Available Pengembangan model Pendidikan Holistik Berbasis Karakter, yang memfokuskan pada pembentukan seluruh aspek dimensi manusia, sehingga dapat menjadi manusia yang berkarakter. Kurikulum Holistik Berbasis Karakter ini disusun berdasarkan Kurikulum Berbasis Kompetensi (KBK dan diterapkan dengan menggunakan pendekatan Student Active Learning, Integrated Learning, Developmentally Appropriate Practices, Contextual Learning, Collaborative Learning, dan Multiple Intelligences yang semuanya dapat menciptakan suasana belajar yang efektif dan menyenangkan, serta dapat mengembangkan seluruh aspek dimensi manusia secara holistik. Maka diperlukan peran yang sangat besar dari guru pembimbing (konselor SMA dalam mengembangkan potensi peserta didiknya dalam mengembangkan potensinya dan membentuk karakter individu itu sendiri dan memberikan warna positif dalam suasana pembelajaran.

Assessing upper limb function in nonambulant SMA patients: development of a new module.

Science.gov (United States)

Mazzone, Elena; Bianco, Flaviana; Martinelli, Diego; Glanzman, Allan M; Messina, Sonia; De Sanctis, Roberto; Main, Marion; Eagle, Michelle; Florence, Julaine; Krosschell, Kristin; Vasco, Gessica; Pelliccioni, Marco; Lombardo, Marilena; Pane, Marika; Finkel, Richard; Muntoni, Francesco; Bertini, Enrico; Mercuri, Eugenio

2011-06-01

We report the development of a module specifically designed for assessing upper limb function in nonambulant SMA patients, including young children and those with severe contractures. The application of the module to a preschool cohort of 40 children (age 30-48 months) showed that all the items could be completed by 30 months. The module was also used in 45 nonambulant SMA patients (age 30 months to 27 years). Their scores were more variable than in the preschool cohort, ranging from 0 to 18. The magnitude of scores was not related to age (r=-0.19). The upper limb scores had a good correlation with the Hammersmith Functional Motor Scale, r=0.75, but the upper limb function did not always strictly follow the overall gross motor function. These findings suggest that even some of the very weak nonambulant children possess upper limb skills that can be measured. Copyright © 2011 Elsevier B.V. All rights reserved.

Refined candidate region specified by haplotype sharing for Escherichia coli F4ab/F4ac susceptibility alleles in pigs

DEFF Research Database (Denmark)

Jacobsen, Mette Juul; Kracht, Steffen Skaarup; Esteso, G.

2009-01-01

Infection of the small intestine by enterotoxigenic Escherichia coli F4ab/ac is a major welfare problem and financial burden for the pig industry. Natural resistance to this infection is inherited as a Mendelian recessive trait, and a polymorphism in the MUC4 gene segregating for susceptibility....../resistance is presently used in a selection programme by the Danish pig breeding industry. To elucidate the genetic background involved in E. coli F4ab/ac susceptibility in pigs, a detailed haplotype map of the porcine candidate region was established. This region covers approximately 3.7 Mb. The material used...... for the study is a three generation family, where the founders are two Wild boars and eight Large White sows. All pigs have been phenotyped for susceptibility to F4ab/ac using an adhesion assay. Their haplotypes are known from segregation analysis using flanking markes. By a targeted approach, the candidate...

Mapping of the bovine spinal muscular atrophy locus to Chromosome 24.

Science.gov (United States)

Medugorac, Ivica; Kemter, Juliane; Russ, Ingolf; Pietrowski, Detlef; Nüske, Stefan; Reichenbach, Horst-Dieter; Schmahl, Wolfgang; Förster, Martin

2003-06-01

A hereditary form of spinal muscular atrophy (SMA) caused by an autosomal recessive gene has been reported for American Brown-Swiss cattle and in advanced backcrosses between American Brown-Swiss and many European brown cattle breeds. Bovine SMA (bovSMA) bears remarkable resemblance to the human SMA (SMA1). Affected homozygous calves also show progressive symmetric weakness and neurogenic atrophy of proximal muscles. The condition is characterized by severe muscle atrophy, quadriparesis, and sternal recumbency as result of neurogenic atrophy. We report on the localization of the gene causing bovSMA within a genomic interval between the microsatellite marker URB031 and the telomeric end of bovine Chromosome (Chr) 24 (BTA24). Linkage analysis of a complex pedigree of German Braunvieh cattle revealed a recombination fraction of 0.06 and a three-point lod score of 11.82. The results of linkage and haplotyping analysis enable a marker-assisted selection against bovSMA based on four microsatellite markers most telomeric on BTA24 to a moderate accuracy of 89-94%. So far, this region is not orthologous to any human chromosome segments responsible for twelve distinct disease phenotypes of autosomal neuropathies. Our results indicate the apoptosis-inhibiting protein BCL2 as the most promising positional candidate gene causing bovSMA. Our findings offer an attractive animal model for a better understanding of human forms of SMA and for a probable anti-apoptotic synergy of SMN-BCL2 aggregates in mammals.

Kinematics of the inner thousand AU region around the young massive star AFGL 2591-VLA3: a massive disk candidate?

NARCIS (Netherlands)

Wang, K. -S.; van der Tak, F. F. S.; Hogerheijde, M. R.

Context. Recent detections of disks around young high-mass stars support the idea of massive star formation through accretion rather than coalescence, but the detailed kinematics in the equatorial region of the disk candidates is not well known, which limits our understanding of the accretion

PENGEMBANGAN MODUL LATIHAN FORGIVENESS UNTUK SISWA SMA DI KOTA MALANG

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Ari Dwi Yudhianto

2016-12-01

Full Text Available This research aims to develop a training modules forgiveness based on the appraisement of experts (reviewers and high school student's response to the training modules forgiveness that have been developed. This study adapting the model development of Borg and Gall (1983, while the structure of the writing module refers to the guide preparation of module which prepared by the Director General module PMPTK (2008. The results of this study are drafting a training module forgiveness for senior high school students in Malang. Based appraisement materials experts, media specialists, and linguists classified as good, according to school counselors classified very good and yield response of students classified as good. So, that these modules worthy be used in the awarding of guidance services in schools. Penelitian ini bertujuan untuk mengembangkan modul latihan forgiveness  berdasarkan penilaian para ahli (reviewer dan respon siswa SMA terhadap Modul latihan forgiveness yang telah dikembangkan. Penelitian ini mengadaptasi model pengembangan Borg and gall (1983, sedangkan struktur penulisan modul mengacu pada panduan penyusunan modul yang disusun oleh dirjen PMPTK (2008. Hasil penelitian ini adalah tersusunnya modul latihan forgiveness untuk siswa SMA di Kota Malang yang berdasarkan penilaian ahli materi, ahli media, dan ahli bahasa tergolong baik, menurut konselor sekolah tergolong sangat baik dan hasil respon siswa tergolong baik. sehingga modul ini layak digunakan dalam pemberian layanan bimbingan di sekolah.

Pola Pembinaan Kompetensi Kepribadian dan Kompetensi Sosial Guru di SMA Muhammadiyah 1 Ponorogo

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Bambang Wahrudin

2017-11-01

Full Text Available This research is motivated by the importance of personal competence and social competence teacher as the spirit of education. The focus of reasearch is know the program fostering personal competence and social competence teacherin SMA Muhammadiyah 1 Ponorogo . Deep observation and interview used in this research by qualitative aproach. The result shows that personality competence development programs conducted in six (6 forms include: 1 Dhuhr and Asr prayers in congregation, 2 Baitul Arqom for teachers and employees, 3 Course / tahsin read the Koran for teachers and employees, 4 Pray tahajud ahad congregation every morning, and 5 Training Motivation and 6 Counseling, whereas social competence training program conducted by three (3 forms, namely: 1 Piket Sympathetic, 2 MGMPs and 3 Sinergy Building. These patern have made theacher have stong  professionaly and  authority Abstrak Penelitian ini dilatarbelakangi oleh pentingnya kompetensi kepribadian dan kompetensi sosial bagi guru sebagai ruh pendidikan. Penelitian ini bertujuan untuk mengetahui program pembinaan kompetensi kepribadian dan kompetensi sosial guru di SMA Muhammadiyah 1 Ponorogo. Reset mendalam dilakukan secara kualitatif. Hasil penelitian menunjukkaan bahwa Program pembinaan kompetensi kepribadian dan kompetensi sosial sumber daya manusia di SMA Muhammadiyah 1 Ponorogo menggunakan 6 (enam bentuk meliputi: 1. sholat Dhuhur dan Ashar berjamaah, 2. baitul Arqom untuk guru dan karyawan, 3. kursus/tahsin baca al-Qur’an untuk guru dan karyawan, 4. sholat tahajud berjamaah setiap ahad dini hari, dan 5. training motivasi dan 6. konseling, sedangkan program pembinaan kompetensi sosial dilakukan dengan 3 (tiga bentuk, yaitu: 1. paket Simpatik, 2.  MGMP dan 3. sinergy Building. Pola ini telah berhasil menghantarkan guru sebagai guru yang profesional yang kuat dan berwibawa.

EVALUASI DAN STRATEGI PENGEMBANGAN SMA INDONESISCH NERDERLANDSCHE SCHOOL (INS KAYUTANAM

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David David

2016-06-01

Full Text Available Penelitian ini bertujuan untuk: (1 mengevaluasi SMA INS Kayutanam dan (2 menyusuan strategi pengembangan SMA INS Kayutanam berdasarkan hasil evaluasi tersebut. Pendekatan yang digunakan dalam penelitian ini adalah kuantitatif dan kualitatif. Sumber data dalam penelitian ini adalah 50 siswa kelas X dan XI, satu kepala sekolah, empat wakil kepala sekolah, 30 guru, dua pembina asrama dan dua orang dari pemerintahan. Hasil penelitian dibagi dalam dua kelompok yaitu hasil evaluasi dan strategi pengembangan. Berdasarkan hasil evaluasi ditemukan bahwa ada beberapa komponen yang perlu perbaikan yaitu kurikulum, kompetensi pendidik dan tenaga kependidikan, fasilitas, peran serta masyarakat, dana dan organisasi. Strategi pengembangan terdiri dari: (1 perumusan kurikulum terintegrasi yang memuat tujuan dan sasaran pendidikan yang diprakarsai oleh Sjafei; (2 perumusan metode mengajar yang sesuai dengan tujuan dan sasaran pendidikan yang diprakasai Sjafei; (3 pengelolaan aset produktif dengan pemanfaatan modal sosial; (4 pemanfaatan basis alumni; (5 membangun kerja sama dengan instansi terkait seperti sekolah lain, pemerintah daerah, dan pihak swasta. Kata kunci: evaluasi, strategi pengembangan   THE EVALUATION AND THE STRATEGY FOR DEVELOPING INDONESISCH NEDERLANDSCHE SCHOOL (INS KAYUTANAM SENIOR HIGH SCHOOL Abstract The study was to: (1 evaluate the development of INS Kayutanam Senior High School; and (2 design the strategy to develop INS Kayutanam Senior High School based on the results of the evaluation. The approach used of in the study was quantitative and qualitative. The data source in the study was 50 students from the X grade and the XI grade, one principal, four vice principals, 30 teachers, two dormitory advisors and two government representatives. The results of the study were divided into two groups namely the evaluation results and the development strategies. Based on the results of the study, the researcher found that there were several

Evaluasi Kenyamanan Termal Ruang Sekolah SMA Negeri di Kota Padang

OpenAIRE

Lusi Susanti; Nike Aulia

2016-01-01

This research aims to determine thermal conditions and sensation of thermal comfort in classrooms of high schools in Padang. This study was conducted in 11 State Senior High School (SMA) represented 11 districts in Padang. About 10% of total student body in each schools were participated in this study to vote thermal comfort questioners. To determine thermal comfort level in this study, PMV (Predicted mean Vote) and PPD (Predicted Percentage of dissatisfied) method were used according to stan...

Development of a Simple Structured Artificial Muscle Using SMA Wire

International Nuclear Information System (INIS)

Ibuki, Ryuta; Maruyama, Shigenao; Komiya, Atsuki

2006-01-01

Artificial heart muscle using SMA wire is developed to assist weaken heartbeat. Simple structure design was adopted for large output force, large displacement and rapid cyclic motion of the actuator. The actuator was designed and fabricated from the viewpoint of heat transfer. Moving performance of the actuator was experimentally measured under 10N of loading condition. Under the maximum efficiency condition, the actuator shows cyclic motion with 1mm of displacement and time period of about 2 seconds in one cycle

Development of a self-stressing NiTiNb shape memory alloy (SMA)/fiber reinforced polymer (FRP) patch

International Nuclear Information System (INIS)

El-Tahan, M; Dawood, M; Song, G

2015-01-01

The objective of this research is to develop a self-stressing patch using a combination of shape memory alloys (SMAs) and fiber reinforced polymer (FRP) composites. Prestressed carbon FRP patches are emerging as a promising alternative to traditional methods to repair cracked steel structures and civil infrastructure. However, prestressing these patches typically requires heavy and complex fixtures, which is impractical in many applications. This paper presents a new approach in which the prestressing force is applied by restraining the shape memory effect of NiTiNb SMA wires. The wires are subsequently embedded in an FRP overlay patch. This method overcomes the practical challenges associated with conventional prestressing. This paper presents the conceptual development of the self-stressing patch with the support of experimental observations. The bond between the SMA wires and the FRP is evaluated using pull-out tests. The paper concludes with an experimental study that evaluates the patch response during activation subsequent monotonic tensile loading. The results demonstrate that the self-stressing patch with NiTiNb SMA is capable of generating a significant prestressing force with minimal tool and labor requirements. (paper)

CHARACTER EDUCATION IN ISLAMIC BOARDING SCHOOL- BASED SMA AMANAH

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Nana Herdiana Abdurrahman

2016-06-01

Full Text Available This paper aims to describe findings of the study in pesantren-based SMA Amanah covering: 1 the principal policy in developing character education, 2 the methods used in developing character education, 3 students’ characteristics as the result of the character education process, 4 the problems encountered in the implementation of character education and the efforts made in addressing the implementation of character education at the school. This study applied qualitative method using descriptive technique. The data were collected through observation, interviews, and documentation. The findings of study showed that: 1 the principal’s policy in developing character education was carried out by implementing government policies in line with the school’s vision, mission, and programs; 2 the methods used in the process of character education were through role-modelling, assignments and nurturing, habituation, training programs, and  students’ participation in various types of activities, as well as the application of rewards and punishments; 3 the student's characteristics resulted from the character  education process were piousness and devotion as well as being able to apply their knowledge and piety in everyday life; 4 problems encountered in the implementation of character education  were different values and norms students brought from home; imbalance of facilities compared to the number of students; as well as teachers’ readiness to actually implement the new program, which  was character education. Meanwhile the efforts made to overcome those problems were namely developing personal, family, neighborhood or community characters, and making commitment of all related parties/stakeholdres of SMA Amanah.

KONSUMSI SUPLEMEN ATLET REMAJA DI SMA RAGUNAN JAKARTA

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Muhammad Q Aliyyan Wijaya

2015-05-01

Full Text Available ABSTRACTThe objective of this study was to investigate consumption of supplement among Ragunan High School Jakarta athletes. The cross sectional study was done with total subjects were 79 students of Ragunan high school who were willing to join the study and they were at school when the study was conducted. There was 92.4% athletes consumed supplement in last one year. All athletes from light and heavy sport category were found consumed supplement. The most popular supplement were vitamin, mineral, and phytonutrition in tablet form. There was 89.0% athletes consumed supplement everyday. Moreover, the main reason for supplementation was to meet a nutrition requirement. The source of information about food supplement was mostly from coach advisor. More than half of athletes got supplement for free from any sources. There was a significant correlation between category of sport and number of supplement used (p<0.05.Keywords: adolescent, athlete, high school, supplementABSTRAKTujuan penelitian adalah menggambarkan konsumsi suplemen pada atlet remaja di SMA Ragunan Jakarta. Desain penelitian ini menggunakan cross sectional dengan total subjek sebanyak 79 siswa SMA Ragunan yang bersedia mengikuti penelitian dan berada di sekolah saat penelitian dilakukan. Sebanyak 92,4% atlet mengaku mengonsumsi suplemen dalam satu tahun terakhir. Atlet dari kategori olahraga ringan dan berat sekali semuanya mengonsumsi suplemen. Suplemen vitamin, mineral, dan fitonutrisi dalam bentuk tablet merupakan jenis dan bentuk suplemen yang paling banyak dikonsumsi. Sebanyak 89,0% dari atlet mengonsumsi suplemen setiap hari. Alasan utama atlet mengonsumsi suplemen adalah untuk memenuhi kebutuhan gizi. Pelatih merupakan sumber infomasi tentang suplemen yang paling banyak dipilih oleh atlet. Lebih dari 50,0% atlet mendapatkan suplemen dengan cara diberi. Kategori olahraga dan jumlah suplemen yang dikonsumsi menunjukkan hubungan positif signifikan (p<0,05.Kata kunci: atlet, remaja

Kelompok Sebaya dan Perilaku Makan Menyimpang Remaja SMA di Jakarta

Directory of Open Access Journals (Sweden)

Rizky Ibrahim Isra

2017-02-01

Full Text Available                                                                          AbstrakTulisan ini membahas hubungan tekanan kelompok sebaya (peer group terhadap gejala perilaku makan menyimpang pada remaja SMA di Jakarta. Banyak studi lain yang mengkaji hal serupa, namun kajian yang membahas permasalahan perilaku makan menyimpang secara sosiologis masih sangat minim. Ketika studi lain hanya memfokuskan pada jenis kelamin perempuan saja, dalam tulisan ini jenis kelamin (laki-laki dan perempuan digunakan sebagai variabel kontrol. Studi sebelumnya yang hanya berfokus pada perempuan memiliki kelemahan karena kelompok sebaya tidak hanya memengaruhi perilaku remaja perempuan, tetapi juga memengaruhi laki-laki. Oleh karena itu, penulis berargumen bahwa kelompok sebaya dapat memengaruhi munculnya gejala perilaku makan menyimpang pada remaja SMA di Jakarta, baik pada laki-laki maupun perempuan. Tulisan ini merupakan hasil studi yang menggunakan metode kuantitatif dengan teknik pengambilan sampel secara acak bertingkat (stratified random sampling sebanyak 235 siswa salah satu SMA negeri di Jakarta. Tulisan ini mengungkapkan bahwa terdapat hubungan antara tekanan kelompok sebaya terhadap gejala perilaku makan menyimpang pada remaja SMA di Jakarta, di mana laki-laki lebih terpengaruh oleh pesan (message dari kelompok sebayanya, sedangkan perempuan lebih kuat terpengaruh oleh interaksi dan likeability.                                                                      AbstractThis article discusses the correlation between peer group pressure and eating disorder behavior symptoms in Jakarta Senior High School students. Many of studies talk about it, but the discussion about eating disorder behavior on sociology was rarely found. In this article, gender was used as a control variable while many of studies only focused on the

Sistem Informasi Data Kepegawaian Dan Kesiswaan SMA Negeri 1 P. Brandan

OpenAIRE

Ramadhani, Tiara

2015-01-01

Tulisan ini bertujuan untuk membangun suatu sistem informasi pada SMA Negeri 1 Babalan P.Brandan. Sistem informasi ini dikembangkan dengan menggunakan perangkat lunak PHP, MySQL, Apache, dan Mozilla Firefox juga software pembantu lainnya seperti Adobe Dreamweaver CS5. Tujuan dari sistem informasi ini adalah untuk menyajikan informasi data kepegawaian, guru, serta kesiswaan kepada user/pengguna dengan baik dan dapat meng-update isi dari informasi yang terdapat pada web tersebut dengan mudah pa...

Biomechanics of smart wings in a bat robot: morphing wings using SMA actuators

International Nuclear Information System (INIS)

Colorado, J; Barrientos, A; Rossi, C; Breuer, K S

2012-01-01

This paper presents the design of a bat-like micro aerial vehicle with actuated morphing wings. NiTi shape memory alloys (SMAs) acting as artificial biceps and triceps muscles are used for mimicking the morphing wing mechanism of the bat flight apparatus. Our objective is twofold. Firstly, we have implemented a control architecture that allows an accurate and fast SMA actuation. This control makes use of the electrical resistance measurements of SMAs to adjust morphing wing motions. Secondly, the feasibility of using SMA actuation technology is evaluated for the application at hand. To this purpose, experiments are conducted to analyze the control performance in terms of nominal and overloaded operation modes of the SMAs. This analysis includes: (i) inertial forces regarding the stretchable wing membrane and aerodynamic loads, and (ii) uncertainties due to impact of airflow conditions over the resistance–motion relationship of SMAs. With the proposed control, morphing actuation speed can be increased up to 2.5 Hz, being sufficient to generate lift forces at a cruising speed of 5 m s −1 . (paper)

Fabrication of wrist-like SMA-based actuator by double smart soft composite casting

Science.gov (United States)

Rodrigue, Hugo; Wei, Wang; Bhandari, Binayak; Ahn, Sung-Hoon

2015-12-01

A new manufacturing method for smart soft composite (SSC) actuators that consists of double casting a SSC actuator to produce an actuator with non-linear shape memory alloy (SMA) wire positioning is proposed. This method is used to manufacture a tube-shaped SSC actuator in which the SMA wires follow the curvature of the tube and is capable of pure-twisting deformations while sustaining a cantilever load. The concept is tested by measuring the maximum twisting angle and a simple control method is proposed to control the twisting angle of the actuator. Then, a soft robotic wrist with a length of 18 cm is built, its load-carrying capability is tested by measuring the cantilever force required for deforming the actuator, and its load-carrying capability during actuation is tested by loading one end with different objects and actuating the actuator. This wrist actuator shows good repeatability, is capable of twisting deformations up to 25° while holding objects weighing 100 g, and can sustain loads above 2 N without undergoing buckling.

Fabrication of wrist-like SMA-based actuator by double smart soft composite casting

International Nuclear Information System (INIS)

Rodrigue, Hugo; Wei, Wang; Bhandari, Binayak; Ahn, Sung-Hoon

2015-01-01

A new manufacturing method for smart soft composite (SSC) actuators that consists of double casting a SSC actuator to produce an actuator with non-linear shape memory alloy (SMA) wire positioning is proposed. This method is used to manufacture a tube-shaped SSC actuator in which the SMA wires follow the curvature of the tube and is capable of pure-twisting deformations while sustaining a cantilever load. The concept is tested by measuring the maximum twisting angle and a simple control method is proposed to control the twisting angle of the actuator. Then, a soft robotic wrist with a length of 18 cm is built, its load-carrying capability is tested by measuring the cantilever force required for deforming the actuator, and its load-carrying capability during actuation is tested by loading one end with different objects and actuating the actuator. This wrist actuator shows good repeatability, is capable of twisting deformations up to 25° while holding objects weighing 100 g, and can sustain loads above 2 N without undergoing buckling. (paper)

Biomechanics of smart wings in a bat robot: morphing wings using SMA actuators.

Science.gov (United States)

Colorado, J; Barrientos, A; Rossi, C; Bahlman, J W; Breuer, K S

2012-09-01

This paper presents the design of a bat-like micro aerial vehicle with actuated morphing wings. NiTi shape memory alloys (SMAs) acting as artificial biceps and triceps muscles are used for mimicking the morphing wing mechanism of the bat flight apparatus. Our objective is twofold. Firstly, we have implemented a control architecture that allows an accurate and fast SMA actuation. This control makes use of the electrical resistance measurements of SMAs to adjust morphing wing motions. Secondly, the feasibility of using SMA actuation technology is evaluated for the application at hand. To this purpose, experiments are conducted to analyze the control performance in terms of nominal and overloaded operation modes of the SMAs. This analysis includes: (i) inertial forces regarding the stretchable wing membrane and aerodynamic loads, and (ii) uncertainties due to impact of airflow conditions over the resistance-motion relationship of SMAs. With the proposed control, morphing actuation speed can be increased up to 2.5 Hz, being sufficient to generate lift forces at a cruising speed of 5 m s(-1).

PENGEMBANGAN MODEL PANDUAN PEMBELAJARAN KETERAMPILAN PROSES SAINS BIOLOGI SMA/MA

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triana asih

2015-10-01

Full Text Available Abstract: Science learning in senior high school was designed with the goal of achieving the competencies of graduates that includes aspects of attitudes, skills, and knowledge competency. Skill aspect refers to the Scientific Approach. Skills such as observing the process are observing, trying, processing, serving, and reasoning. All of these skills, leading to the aspects that exist within SPS. Learning needs analysis conducted by researchers at the SMA/ MA class XI IPA that is in the Purbolinggo district of East Lampung SPS shows a lack of provision in the learning process. Supposedly, learning based  on SPS is further enhanced, the researchers created a learning guide model based on SPS. The objectives of the reasearch: 1 produce a learning guide model based on SPS class XI, 2 improve outcomes (process and output (learning cutcomes biology learning class XI. Type of the research is Research and Development (R&D. The research was conducted in SMA N 1 Purbolinggo in class XI Science. Procedures R&D is adapted from Borg and Gall consisting of five steps: 1 literature review and the results of relevant research, 2 Design and carry out preliminary study, 3 the development/conceptualization models, 4 test the model through experimentation, 5 revision of the model. conclusion; 1 learning guide SPS models has been validated by the user and learning experts, instrument validation, model validation, and it is suitable.

Pengaruh Sistem Manajemen Mutu ISO 9001:2008 dan Kompensasi Terhadap Kinerja Guru di SMA Darul Ulum 2 Unggulan BPPT Jombang

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Mochamad Yusuf

2017-12-01

Full Text Available This article discusses the influence of the ISO 9001:2008 quality management system and compensation for teacher performance in SMA Darul Ulum 2 Unggulan BPPT Jombang. The purpose of this research is: to know the influence of SMM 9001:2008 implementation to the teacher performance; to know the influence of the compensation for teacher performance; to find out the influence of the SMM ISO 9001:2008 implementation and the compensation simultaneously on the teacher performance. This is a correlational research with an expost facto approach. The population of this study are all teachers in SMA Darul Ulum 2 Unggulan BPPT Jombang that amounted to 92 people. The methods of data collection in this study using questionnaires. Based on the research conducted, it was concluded that the implementation of ISO 9001:2008 quality management system and the the compensation either apart or together are very closely related to the teacher performance in Darul Ulum 2 SMA Unggulan BPPT Jombang.

Embedded SMA wire actuated biomimetic fin: a module for biomimetic underwater propulsion

International Nuclear Information System (INIS)

Wang Zhenlong; Hang Guanrong; Wang Yangwei; Li Jian; Du Wei

2008-01-01

An embedded shape memory alloy (SMA) wire actuated biomimetic fin is presented, and based on this module for biomimetic underwater propulsion, a micro robot fish (146 mm in length, 30 g in weight) and a robot squid (242 mm in length, 360 g in weight) were developed. Fish swim by undulating their body and/or fins. Squid and cuttlefish can also swim by undulating their fins. To simplify engineering modeling, the undulating swimming movement is assumed to be the integration of the movements of many flexible bending segments connected in parallel or in series. According to this idea, a biomimetic fin which can bend flexibly was developed. The musculature of a cuttlefish fin was investigated to aid the design of the biomimetic fin. SMA wires act as 'muscle fibers' to drive the biomimetic fin just like the transverse muscles of the cuttlefish fin. During the bending phase, elastic energy is stored in the elastic substrate and skin, and during the return phase, elastic energy is released to power the return movement. Theorem analysis of the bending angle was performed to estimate the bending performance of the biomimetic fin. Experiments were carried out on single-face fins with latex rubber skin and silicone skin (SF-L and SF-S) to compare the bending angle, return time, elastic energy storage and reliability. Silicone was found to be the better skin. A dual-face fin with silicone skin (DF-S) was tested in water to evaluate the actuating performance and to validate the reliability. Thermal analysis of the SMA temperature was performed to aid the control strategy. The micro robot fish and robot squid employ one and ten DF-S, respectively. Swimming experiments with different actuation frequencies were carried out. The speed and steering radius of the micro robot fish reached 112 mm s −1 and 136 mm, respectively, and the speed and rotary speed of the robot squid reached 40 mm s −1 and 22° s −1 , respectively

EVALUASI KINERJA GURU FISIKA, BIOLOGI DAN KIMIA SMA YANG SUDAH LULUS SERTIFIKASI

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Yusrizal Yusrizal

2013-01-01

Full Text Available Penelitian ini bertujuan (1 mengembangkan instrumen evaluasi kinerja guru yang valid dan reliabel, (2 mengevaluasi kinerja guru Fisika, Biologi, dan Kimia SMA yang sudah terser-tifikasi/menerima tunjangan profesi. Populasi penelitian yaitu seluruh guru Fisika, Biologi dan Kimia SMA tersertifikasi/pene-rima tunjangan profesi yang berada di Kota Banda Aceh, Kabupaten Aceh Besar dan Kabupaten Pidie. Validitas konstruk instrumen yang dikembangkan dibuktikan melalui analisis fak-tor, dan reliabilitasnya diestimasi dengan rumus alpha Cron-bach. Analisis tingkat kinerja ditentukan dengan persentase. Hasil penelitian menunjukkan: (1 instrumen yang dikembang-kan terdiri atas 33 butir pernyataan, dan memiliki koefisien reliabilitas konsistensi internal sebesar 0,953; (2 kinerja guru Fisika, Biologi, dan Kimia SMA yang sudah lulus sertifikasi dan sudah menerima tunjangan belum seluruhnya berkinerja tinggi; (3 kinerja guru Kimia relatif lebih baik dari pada kinerja guru Biologi dan guru Fisika. Kata kunci: evaluasi, kinerja guru, validitas, reliabilitas ______________________________________________________________ AN EVALUATION OF THE PERFORMANCE OF CERTIFIED SCIENCE TEACHERS (PHYSICS, CHEMISTRY AND BIOLOGY OF SENIOR HIGH SCHOOLS Abstract This study was aimed at (1 developing a valid and reliable performance evaluation instruments for teachers, and (2 evaluating the level of Physics, Biology and Chemistry teachers of senior high schools who have been certified and received theprofession allowance. The population of this study included all certified Physics, Biology and Chemistry teachers of senior high schools who have received profession allowance in Banda Aceh, Aceh Besar, and Pidie. The construct validity of the instrument developed was assessed through factor analysis, and the reliability was estimated by using Cronbach’s Alpha formula. The level of teachers’performance was analyzed by the percentage. The result of the research shows that (1 the

RELEVANSI KURIKULUM PRODI PENDIDIKAN SOSIOLOGI ANTROPOLOGI DENGAN KEBUTUHAN MENGAJAR GURU SMA

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Totok Rochana

2013-04-01

Full Text Available Materi pembelajaran  Sosiologi dan Antropologi yang diajarkan di SMA senantiasa mengalami perubahan. Sementara  kurikulum Program Studi Pendidikan Sosiologi dan Antropologi FIS UNNES tidak banyak mengalami perubahan. Dalam penelitian ini, penulis membahas bagaimana relevansi antara Kurikulum Prodi Pendidikan Sosiologi dan Antropologi FIS UNNES dengan kebutuhan mengajar bagi guru Sosiologi dan Antropologi SMA Negeri di Jawa Tengah. Penelitian ini menggunakan pendekatan kualitatif dan  bersifat kasus, pengumpulan data menggunakan metode wawancara tertutup dan terbuka, dan analisis data  menggunakan metode deskriptif kualitatif. Berdasarkan hasil penelitian  disimpulkan bahwa kurikulum  Program Studi Pendidikan Sosiologi dan Antropologi FIS UNNES, masih relevan dengan materi pembelajaran Sosiologi dan Antropologi yang diajarakan di SMA. Saran yang diajukan adalah: perlu diselenggarakan penataran-penataran/diklat-diklat peningkatan penguasaan materi pembelajaran Sosiologi dan Antropologi bagi guru-guru Sosiologi dan Antropologi yang bukan berlatar belakang Pendidikan Sosiologi dan Antropologi. Pengangkatan CPNS Guru Sosiologi dan Antropologi perlu diprioritaskan dari lulusan Prodi Pendidikan Sosiologi dan Antropologi. Pengembangan kurikulum Program Studi Pendidikan Sosiologi dan Antropologi tetap mengacu pada relevansinya dengan kebutuhan di lapangan.Sociology and Anthropology instructional materials taught in high school are constantly changing, though the curriculum of Sociology and Anthropology FIS Unnes does not change much. In this study, the author discusses the relevance of the curriculum of Sociology and Anthropology of Education Unnes FIS to the needs of teaching for teachers of Sociology and Anthropology Senior high school in Central Java. The method used in this study is a qualitative approach using descriptive methods. Based on the results of the study it is concluded that the curriculum of Sociology and Anthropology

Development of transformation bands in TiNi SMA for various stress and strain rates studied by a fast and sensitive infrared camera

International Nuclear Information System (INIS)

Pieczyska, E A; Kulasinski, K; Tobushi, H

2013-01-01

TiNi shape memory alloy (SMA) was subjected to tension at various strain rates for stress- and strain-controlled tests. The nucleation, development and saturation of the stress-induced martensitic transformation were investigated, based on the specimen temperature changes, measured by a fast and sensitive infrared camera. It was found that the initial, macroscopically homogeneous phase transformation occurs at the same stress level for all strain rates applied, regardless of the loading manner, while the stress of the localized transformation increases with the strain rate. At higher strain rate, a more dynamic course of the transformation process was observed, revealed in the creation of numerous fine transformation bands. An inflection point was noticed on the stress–strain curve, dividing the transformation range into two stages: the first heterogeneous, where transformation bands nucleate and evolve throughout the sample; the second, where the bands overlap, related to significant temperature increase and an upswing region of the curve. In the final part of the SMA loading a decrease of the average sample temperature revealed the saturation stage of the transformation. It was also observed that nucleation of the localized martensitic forward transformation takes place in the weakest area of the sample in both approaches, whereas the reverse transformation always initiates in its central part. (paper)

Identification of chromosome 7 inversion breakpoints in an autistic family narrows candidate region for autism susceptibility.

Science.gov (United States)

Cukier, Holly N; Skaar, David A; Rayner-Evans, Melissa Y; Konidari, Ioanna; Whitehead, Patrice L; Jaworski, James M; Cuccaro, Michael L; Pericak-Vance, Margaret A; Gilbert, John R

2009-10-01

Chromosomal breaks and rearrangements have been observed in conjunction with autism and autistic spectrum disorders. A chromosomal inversion has been previously reported in autistic siblings, spanning the region from approximately 7q22.1 to 7q31. This family is distinguished by having multiple individuals with autism and associated disabilities. The region containing the inversion has been strongly implicated in autism by multiple linkage studies, and has been particularly associated with language defects in autism as well as in other disorders with language components. Mapping of the inversion breakpoints by FISH has localized the inversion to the region spanning approximately 99-108.75 Mb of chromosome 7. The proximal breakpoint has the potential to disrupt either the coding sequence or regulatory regions of a number of cytochrome P450 genes while the distal region falls in a relative gene desert. Copy number variant analysis of the breakpoint regions detected no duplication or deletion that could clearly be associated with disease status. Association analysis in our autism data set using single nucleotide polymorphisms located near the breakpoints showed no significant association with proximal breakpoint markers, but has identified markers near the distal breakpoint ( approximately 108-110 Mb) with significant associations to autism. The chromosomal abnormality in this family strengthens the case for an autism susceptibility gene in the chromosome 7q22-31 region and targets a candidate region for further investigation.

STUDI KASUS PENERAPAN PENDEKATAN SAINTIFIK PADA GURU-GURU DI SMA N 1 BAWANG (STUDI PADA TAHUN AJARAN 2013/2014

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Mei Fita Aryani

2014-11-01

Full Text Available Pendekatan saintifik adalah pendekatan yang digunakan dalam kurikulum 2013. Sebagian besar guru di SMA N 1 Bawang belum menerapkan pendekatan saintifik. Penelitian ini dilakukan di SMA N 1 Bawang Kabupaten Batang dengan menggunakan pendekatan kualitatif studi kasus. Sumber data yang digunakan dalam penelitian ini yaitu sumber data manusia dan benda. Teknik pengumpulan data observasi, wawancara semiterstruktur dan dokumentasi. Keabsahan data diuji melalui triangulasi sumber. Hasil penelitian menunjukan bahwa sebagian guru belum menerapkan pendekatan saintifik dalam pembelajaran. Beberapa guru yang mengajar masih mengalami hambatan dalam penerapan pendekatan saintifik. Dalam perencanaan hambatan yang dialami guru yaitu: (1 hambatan dalam penyusunan RPP 2013, (2 pengembangan RPP, (3 kesulitan dalam menyiapkan media pembelajaran. Dalam pelaksanaan pembelajaran, hambatan yang dialami guru yaitu: (1 sulitnya menarik minat siswa untuk bertanya, (2 kurangnya waktu, (3 rumitnya persiapan, (4 guru kurang mampu mengelola kelas, (5 siswa banyak yang terlambat mengumpulkan tugas. Dalam kegiatan penilaian hambatannya yaitu (1 guru masih kesulitan dalam melakukan penilaian kepada siswa secara bersamaan, (2 guru masih bingung membuat instrument penilaian. Faktor pendukung penerapan pendekatan saintifik di SMA N 1 Bawang sangat di dukung oleh kemampuan guru dan sarana prasarana yang sudah cukup lengkap. Scientific approach is the approach used in the curriculum 2013. Most of the teachers SMA N 1 Bawang not apply scientific approach. This research was conducted in SMA N 1 Bawang in the Batang Regency using a qualitative case study approach. Sources of data used in this research that the human data sources and object. Data collection techniques of observation, semistructured interviews and documentation. The validity is tested through triangulation of data sources. The results showed that the majority of teachers have not applied a scientific approach to learning

A 1.3 mm SMA survey of 29 variable young stellar objects

Science.gov (United States)

Liu, Hauyu Baobab; Dunham, Michael M.; Pascucci, Ilaria; Bourke, Tyler L.; Hirano, Naomi; Longmore, Steven; Andrews, Sean; Carrasco-González, Carlos; Forbrich, Jan; Galván-Madrid, Roberto; Girart, Josep M.; Green, Joel D.; Juárez, Carmen; Kóspál, Ágnes; Manara, Carlo F.; Palau, Aina; Takami, Michihiro; Testi, Leonardo; Vorobyov, Eduard I.

2018-04-01

Context. Young stellar objects (YSOs) may undergo periods of active accretion (outbursts), during which the protostellar accretion rate is temporarily enhanced by a few orders of magnitude. Whether or not these accretion outburst YSOs possess similar dust and gas reservoirs to each other, and whether or not their dust and gas reservoirs are similar as quiescent YSOs, are issues yet to be clarified. Aims: The aim of this work is to characterize the millimeter thermal dust emission properties of a statistically significant sample of long and short duration accretion outburst YSOs (i.e., FUors and EXors) and the spectroscopically identified candidates of accretion outbursting YSOs (i.e., FUor-like objects). Methods: We have carried out extensive Submillimeter Array (SMA) observations mostly at 225 GHz (1.33 mm) and 272 GHz (1.10 mm), from 2008 to 2017. We covered accretion outburst YSOs located at database of 29 objects. We obtained 21 detections at >3σ significance. Detected sources except for the two cases of V883 Ori and NGC 2071 MM3 were observed with 1″ angular resolution. Overall our observed targets show a systematically higher millimeter luminosity distribution than those of the M* > 0.3 M⊙ Class II YSOs in the nearby (≲400 pc) low-mass star-forming molecular clouds (e.g., Taurus, Lupus, Upp Scorpio, and Chameleon I). In addition, at 1 mm our observed confirmed binaries or triple-system sources are systematically fainter than the rest of the sources even though their 1 mm fluxes are broadly distributed. We may have detected 30-60% millimeter flux variability from V2494 Cyg and V2495 Cyg, from the observations separated by approximately one year.

A self-driven temperature and flow rate co-adjustment mechanism based on Shape-Memory-Alloy (SMA) assembly for an adaptive thermal control coldplate module with on-orbit service characteristics

International Nuclear Information System (INIS)

Guo, Wei; Li, Yunhua; Li, Yun-Ze; Zhong, Ming-Liang; Wang, Sheng-Nan; Wang, Ji-Xiang; Zhang, Jia-Xun

2017-01-01

Highlights: • A self-driven temperature and flow rate co-adjustment mechanism based on SMA assembly is proposed. • An adaptive thermal control coldplate module (TCCM) is introduced. • A testbed is set up to investigate the TCCM adaptive thermal management performances. • The TCCM has the potential for spacecrafts on-orbit services. - Abstract: An adaptive thermal control coldplate module (TCCM) was proposed in this paper to fulfill the requirements of modular thermal control systems for spacecrafts on-orbit services. The TCCM could provide flow rate and temperature co-adjustment by using Shape-Memory-Alloy (SMA) assembly which possesses self-driven abilities. In this paper, the adaptive thermal management mechanism of the TCCM integrated with a single phase mechanically pumped fluid loop (SPMPFL) is described in detail, a verification testbed was established to examine the TCCM dynamic characteristics. Various working conditions such as inlet temperature, flow rate and thermal load disturbances were imposed on the TCCM to inspect its startup and transient performance. It was observed that the TCCM may present robust temperature control results with low overshoot (maximum 16.8%) and small temperature control error (minimum 0.18%), fast time response (minimum 600 s) was also revealed. The results demonstrated that the well-designed TCCM provided effective autonomous flow-rate and temperature co-adjustment operations, which may be a promising candidate for realizing modular level adaptive thermal management for spacecrafts on-orbit services.

Star Formation Activity Beyond the Outer Arm. I. WISE -selected Candidate Star-forming Regions

Energy Technology Data Exchange (ETDEWEB)

Izumi, Natsuko; Yasui, Chikako; Saito, Masao [National Astronomical Observatory of Japan, 2-21-1, Osawa, Mitaka, Tokyo 181-8588 (Japan); Kobayashi, Naoto; Hamano, Satoshi, E-mail: natsuko.izumi@nao.ac.jp [Laboratory of Infrared High-resolution spectroscopy (LIH), Koyama Astronomical Observatory, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555 (Japan)

2017-10-01

The outer Galaxy beyond the Outer Arm provides a good opportunity to study star formation in an environment significantly different from that in the solar neighborhood. However, star-forming regions in the outer Galaxy have never been comprehensively studied or cataloged because of the difficulties in detecting them at such large distances. We studied 33 known young star-forming regions associated with 13 molecular clouds at R {sub G} ≥ 13.5 kpc in the outer Galaxy with data from the Wide-field Infrared Survey Explorer ( WISE ) mid-infrared all-sky survey. From their color distribution, we developed a simple identification criterion of star-forming regions in the outer Galaxy with the WISE color. We applied the criterion to all the WISE sources in the molecular clouds in the outer Galaxy at R {sub G} ≥ 13.5 kpc detected with the Five College Radio Astronomy Observatory (FCRAO) {sup 12}CO survey of the outer Galaxy, of which the survey region is 102.°49 ≤  l  ≤ 141.°54, −3.°03 ≤  b  ≤ 5.°41, and successfully identified 711 new candidate star-forming regions in 240 molecular clouds. The large number of samples enables us to perform the statistical study of star formation properties in the outer Galaxy for the first time. This study is crucial to investigate the fundamental star formation properties, including star formation rate, star formation efficiency, and initial mass function, in a primordial environment such as the early phase of the Galaxy formation.

UPAYA MENGEMBANGKAN LEARNING COMMUNITY SISWA KELAS X SMA MELALUI PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPE STAD BERBASIS CTL PADA PEMBELAJARAN FISIKA

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Wahyudi -

2012-04-01

Full Text Available Penelitian ini bertujuan untuk mendeskripsikan penerapan model pembelajaran kooperatif tipe STAD berbasis CTL pada pembelajaran fisika dalam mengembangkan learning community dan meningkatkan hasil belajar siswa serta mengetahui dampak penerapannya terhadap learning community dan hasil belajar siswa kelas X-7 SMA N 1 Tahunan Jepara. Hasil penelitian menunjukkan meningkatnya hasil belajar serta berkembangnya learning community siswa kelas X-7 SMA N 1 Tahunan Jepara setelah penerapan model pembelajaran kooperatif tipe STAD berbasis CTL pada pokok bahasan listrik dinamis.This research is describe the implementation of cooperative learning model STAD CTL-based for Physics learning subject to develop learning community, improve students learning and also find out the outcome of its implementation  to the learning community and learning result of SMA N 1 Tahunan Jepara Students class of X-7. The research result shows that there is an improvement of students’ learning result and also a development of learning community of N 1 Tahunan Jepara Students class of X-7 after implementing cooperative learning model STAD CTL-based for Dynamic Electricity topic.

PERAN GURU BIMBINGAN DAN KONSELING DALAM MENINGKATKAN KESUKSESAN BELAJAR SISWA DI SMA NEGERI 1 DEPOK SLEMAN YOGYAKARTA

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Mahdi Mahdi

2017-05-01

Full Text Available This study was to determine the role of guidance and counseling teachers in improving student learning success at SMA Negeri 1 Depok Sleman, Yogyakarta. The method used in this research is descriptive qualitative manifold generate descriptive data to describe the behavior of the subject under study. Then the presence of investigators in this study serves as primary research tool. Sources of data in this study are primary data obtained through observation and interview respondents. And secondary data documentation Master's programs of guidance and counseling. Data collection techniques in this study using the method of observation, interviews, and documentation. Selanjtnya data analysis in this study using qualitative data analysis. The results showed that the models of guidance and counseling program in SMA Negeri 1 Depok form their Intensification Program for class XII, intensification program contains material National Examinations and Pathways to college, learning programs in addition to class 10 and 11 to face the Final Exams Semester in order to satisfy student achievement, educational exhibits, and extracurricular programs in SMA Negeri 1 Depok. Then the data findings in the form of involvement or role of teacher guidance and counseling in improving students' success in school is through a program of classical guidance, counseling and personal counseling, tutoring and social counseling, guidance and counseling to learn, and guidance and career counseling.

PENGARUH MODEL PEMBELAJARAN DAN KESADARAN METAKOGNITIF TERHADAP HASIL BELAJAR PESERTA DIDIK SMA DALAM MATERI POKOK ASAM BASA

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Wiwiek Tamsyani

2016-06-01

Full Text Available Penelitian ini bertujuan untuk mengkaji hasil belajar penyebaran dengan model pembelajaran penemuan dan inkuiri terbimbing menggunakan rancangan quasi eksperimen dengan desain faktorial 2 × 2. Penelitian dilaksanakan di SMA Negeri 2 Takalar. Sampel penelitian dipilih dengan random sampling teknik acak kelas yang terdiri atas 2 kelas. Kelas XI IPA 1 (34 peserta didik sebagai kelas eksperimen 1 dibelajarkan dengan model pembelajaran penemuan dan kelas XI IPA 2 (33 peserta didik sebagai kelas eksperimen 2 dibelajarkan dengan model pembelajaran inkuiri terbimbing. Instrumen penelitian menggunakan yaitu, angket Inventori Kesadaran Meta kognitif dan tes hasil belajar. Penggunaan program SPSS versi 20.0 menunjukkan bahwa 5 soal essay valid dengan reliabilitas sebesar instrumen sebesar 0.699. Data penelitian dianalisis pada taraf signifikan α = 0.05 dengan uji anova dua jalur. Hasil penelitian menunjukkan bahwa (1 Rata-rata nilai hasil belajar peserta didik yang menggunakan model pembelajaran penemuan, hasilnya lebih tinggi dibandingkan dengan model pembelajaran inkuiri terbimbing. (2 Rata-rata nilai hasil belajar peserta didik dengan kesadaran metakognitif tinggi, hasil belajar peserta didik lebih tinggi dibandingkan dengan rata-rata nilai hasil belajar dengan kesadaran metakognitif rendah. (3 Terjadi interaksi antara model pembelajaran dan kesadaran metakognitif dalam mempengaruhi hasil belajar SMA Negeri 2 Takalar. Jadi, ada pengaruh antara model pembelajaran dan kesadaran metakognitif terhadap hasil belajar peserta didik SMA Negeri 2 Takalar dalam materi pokok asam basa.

Pengaruh Penerapan Model Pembelajaran Berbasis Masalah Terhadap Kemampuan Menulis Teks Eksposisi Oleh Siswa Kelas X SMA Negeri 1 Babalan Tahun Pembelajaran 2013/2014

OpenAIRE

ulfa, warni atul

2013-01-01

Penelitian ini bertujuan untuk mengetahui pengaruh penerapan Model Pembelajaran Berbasis Masalah terhadap kemampuan menulis teks eksposisi oleh siswa kelas X SMA Negeri 1 Babalan tahun pembelajaran 2013/2014. Populasi penelitian ini adalah seluruh siswa kelas X SMA Negeri 1 Babalan, yang berjumlah 200 orang dan yang menjadi sampel penelitian sebanyak 40 orang. Pengambilan sampel dilakukan dengan cara menentukan satu kelas yang dijadikan wakil populasi dengan menggunakan teknik Random Sampling...

MwoI and SmaI RFLPs polymorphisms of porcine obese gene and their association with carcass and meat characteristics of heavy pigs

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Giorgio Graziosi

2010-01-01

Full Text Available The obese gene encodes leptin, a 16-kDa protein involved in the regulation of fat deposition and energy consumption.Backfat is one of the peculiar characteristics of Italian ham, and represents a fundamental quality factor. Therefore, theobese gene can be considered as a candidate marker for determining economically important production traits such asbackfat thickness, feed intake, and growth rate in swine. The aim was to investigate the relationship between obese genepolymorphisms and carcass and meat characteristics of pigs reared for ham production. In the present research, the analysesof three new RFLPs are reported. An MwoI polymorphism occurs at nucleotide 1792, within the intron. Pigs heterozygousat this position have heavier thighs with a thinner layer of fat. Two SmaI polymorphisms occur at nucleotides5018 and 5410 within the 3’ UTR of the obese gene. Animals heterozygous at position 5410 have characteristics suitablefor the production of San Daniele ham: lower backfat thickness and heavier thighs with a thinner fat layer, relative toother genotypes.

Analisis pengelolaan peralatan praktikum fisika kelas XI SMA Muhammadiyah 1 Yogyakarta menggunakan model countenance stake

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Hanin Fathan Nurfina Istiqomah

2016-11-01

Full Text Available Penelitian ini bertujuan untuk mengetahui ketersediaan dan pengelolaan peralatan praktikum serta mengetahui hasil dari pengelolaan dan penggunaan peralatan praktikum fisika kelas XI di laboratorium fisika SMA Muhammadiyah 1 Yogyakarta. Penelitian ini merupakan penelitian evalusi model countenance stake. Subjek penelitian meliputi penanggungjawab laboratorium fisika, guru, laboran, dan siswa kelas XI MIA SMA Muhammadiyah 1 Yogyakarta. Penelitian dilakukan pada akhir pelaksanaan praktikum pada semester genap tahun pelajaran 2015-2016. Data dikumpulkan dengan wawancara terstruktur, pengamatan (observasi, angket, dokumentasi. Hasil penelitian menunjukkan bahwa ketersediaan peralatan praktikum (masukan [antecedents] yang terdiri dari sarana, prasarana dan alat praktikum tersedia sangat baik dengan persentase sebesar 78,16%. Pengelolaan laboratorium fisika (proses [transaction] yang terdiri dari persiapan pelaksanaan praktikum; kesiapan siswa, guru, laboran; dan pelaksanaan praktikum mendapatkan hasil sangat baik dengan persentase sebesar 81,78%. Hasil yang diperoleh (outcomes dari ketersediaan dan pengelolaan peralatan praktikum di laboratorium fisika termasuk kategori baik (B+ dengan pencapaian Kriteria Ketuntasan Minimal (KKM 100% dari total 233 siswa kelas XI MIA (Matematika dan Ilmu Alam dan beberapa siswa berhasil meraih juara 1 Olimpiade Fisika. This research is aimed to know the availability, management of the laboratory equipment’s and also the result of maintaining and using physics laboratory equipment’s in 11th class of MIA SMA 1 Muhammadiyah Yogyakarta. And this evaluation research used “countenance stake” approach, hence, such as the objects of it is the physics laboratory care taker, teachers, laboratory assistant, and the students. This research was conducted in the last meeting of practicum on last semester 2015-2016 periods. The data was assembled by interview, observation, questionnaire and documentation. The result of this

Membrane protein extraction and purification using styrene-maleic acid (SMA) copolymer: effect of variations in polymer structure.

Science.gov (United States)

Morrison, Kerrie A; Akram, Aneel; Mathews, Ashlyn; Khan, Zoeya A; Patel, Jaimin H; Zhou, Chumin; Hardy, David J; Moore-Kelly, Charles; Patel, Roshani; Odiba, Victor; Knowles, Tim J; Javed, Masood-Ul-Hassan; Chmel, Nikola P; Dafforn, Timothy R; Rothnie, Alice J

2016-12-01

The use of styrene-maleic acid (SMA) copolymers to extract and purify transmembrane proteins, while retaining their native bilayer environment, overcomes many of the disadvantages associated with conventional detergent-based procedures. This approach has huge potential for the future of membrane protein structural and functional studies. In this investigation, we have systematically tested a range of commercially available SMA polymers, varying in both the ratio of styrene and maleic acid and in total size, for the ability to extract, purify and stabilise transmembrane proteins. Three different membrane proteins (BmrA, LeuT and ZipA), which vary in size and shape, were used. Our results show that several polymers, can be used to extract membrane proteins, comparably to conventional detergents. A styrene:maleic acid ratio of either 2:1 or 3:1, combined with a relatively small average molecular mass (7.5-10 kDa), is optimal for membrane extraction, and this appears to be independent of the protein size, shape or expression system. A subset of polymers were taken forward for purification, functional and stability tests. Following a one-step affinity purification, SMA 2000 was found to be the best choice for yield, purity and function. However, the other polymers offer subtle differences in size and sensitivity to divalent cations that may be useful for a variety of downstream applications. © 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.

MODEL PERMAINAN AKTIVITAS LUAR KELAS UNTUK MENGEMBANGKAN RANAH KOGNITIF, AFEKTIF, DAN PSIKOMOTORIK SISWA SMA

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Hendra Setyawan

2015-10-01

Full Text Available Penelitian ini bertujuan menghasilkan model-model permainan Aktivitas Luar kelas (ALK yang layak digunakan sebagai materi pembelajaran penjas, serta efektif untuk mengembangkan ranah kognitif, afektif, dan psikomotorik siswa SMA. Penelitian ini dilakukan dengan langkah-langkah sebagai berikut: (1 pengumpulan informasi di lapangan, (2 menganalisis informasi yang telah dikumpulkan, (3 mengembangkan produk awal, (4 validasi ahli dan revisi, (5 uji coba skala kecil dan  revisi, (6 uji coba skala besar dan revisi, dan (7 pembuatan produk final. Uji coba skala kecil dilakukan terhadap siswa kelas X-D dan XI-IPA 4 dari SMA N I Prambanan berjumlah 66 orang. Uji coba skala besar dilakukan terhadap siswa kelas X-G, X-H, XI-IPS 3, dan XI-BHS dari SMA N I Prambanan berjumlah 132 orang. Instrumen pengumpulan data yang digunakan yaitu; (1 pedoman wawancara, (2 skala nilai, (3 pedoman observasi permainan, (4 pedoman observasi keefektifan permainan, (5 pedoman observasi terhadap guru pelaku uji coba, dan (6 rubrik penilaian siswa. Teknik analisis data dengan analisis deskriptif kuantitatif dan kualitatif. Hasil penelitian berupa tujuh model permainan yang layak dan efektif digunakan dalam pembelajaran penjas, hal ini dibuktikan dengan perolehan persentase sebesar 100% dari data hasil kuesioner skala nilai, observasi model permainan, observasi keefektifan permainan, dan observasi guru pelaku uji coba. Model permainan juga efektif untuk mengembangkan ranah kognitif, afektif, dan psikomotorik, yang dibuktikan dengan terjadinya peningkatan persentase nilai rata-rata siswa sebesar 21%. Kata kunci: model, permainan, aktivitas luar kelas, kognitif, afektif, psikomotorik THE OUTDOOR ACTIVITY GAME MODEL TO DEVELOP THE ASPECT OF COGNITIVE, AFFECTIVE, AND PSYCHOMOTOR OF THE SENIOR HIGH SCHOOL STUDENTS Abstract This study aims at producing outdoor activity game models which are proper to be used for physicall education learning and developing cognitive, affective, and

Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model.

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Ando, Shiori; Funato, Michinori; Ohuchi, Kazuki; Kameyama, Tsubasa; Inagaki, Satoshi; Seki, Junko; Kawase, Chizuru; Tsuruma, Kazuhiro; Shimazawa, Masamitsu; Kaneko, Hideo; Hara, Hideaki

2017-11-05

Spinal muscular atrophy (SMA) is an intractable disease characterized by a progressive loss of spinal motor neurons, which leads to skeletal muscle weakness and atrophy. Currently, there are no curative agents for SMA, although it is understood to be caused by reduced levels of survival motor neuron (SMN) protein. Additionally, why reduced SMN protein level results in selective apoptosis in spinal motor neurons is still not understood. Our purpose in this study was to evaluate the therapeutic potential of edaravone, a free radical scavenger, by using induced pluripotent stem cells from an SMA patient (SMA-iPSCs) and to address oxidative stress-induced apoptosis in spinal motor neurons. We first found that edaravone could improve impaired neural development of SMA-iPSCs-derived spinal motor neurons with limited effect on nuclear SMN protein expression. Furthermore, edaravone inhibited the generation of reactive oxygen species and mitochondrial reactive oxygen species upregulated in SMA-iPSCs-derived spinal motor neurons, and reversed oxidative-stress induced apoptosis. In this study, we suggest that oxidative stress might be partly the reason for selective apoptosis in spinal motor neurons in SMA pathology, and that oxidative stress-induced apoptosis might be the therapeutic target of SMA. Copyright © 2017 Elsevier B.V. All rights reserved.

PENGEMBANGAN BUKU PEDOMAN GURU PADA PEMBELAJARAN FISIKA SMA MENGGUNAKAN MODEL PROBLEM SOLVING LEVEL INKUIRI

OpenAIRE

Susi Fatikhah Setiyawati; Heru Kuswanto

2015-01-01

Penelitian ini bertujuan: (1) menghasilkan buku pedoman guru untuk pembelajaran fisika SMA menggunakan model problem solving sesuai level inkuiri yang layak digunakan; (2) mendeskripsikan keberhasilan pembelajaran fisika menggunakan model problem solving (MPS) sesuai dengan level inkuiri sesuai dengan buku pedoman terhadap peningkatan aktivitas peserta didik dan kemampuan berpikir kritis peserta didik. Penelitian ini merupakan penelitian pengembangan, sesuai langkah yang dikembangkan oleh Bor...

Artificial heart for humanoid robot using coiled SMA actuators

Science.gov (United States)

Potnuru, Akshay; Tadesse, Yonas

2015-03-01

Previously, we have presented the design and characterization of artificial heart using cylindrical shape memory alloy (SMA) actuators for humanoids [1]. The robotic heart was primarily designed to pump a blood-like fluid to parts of the robot such as the face to simulate blushing or anger by the use of elastomeric substrates for the transport of fluids. It can also be used for other applications. In this paper, we present an improved design by using high strain coiled SMAs and a novel pumping mechanism that uses sequential actuation to create peristalsis-like motions, and hence pump the fluid. Various placements of actuators will be investigated with respect to the silicone elastomeric body. This new approach provides a better performance in terms of the fluid volume pumped.

RhoA, Rac1 and Cdc42 differentially regulate aSMA and collagen I expression in mesenchymal stem cells.

Science.gov (United States)

Ge, Jianfeng; Burnier, Laurent; Adamopoulou, Maria; Kwa, Mei Qi; Schaks, Matthias; Rottner, Klemens; Brakebusch, Cord

2018-04-26

Mesenchymal stem cells (MSC) are suggested to be important progenitors of myofibroblasts in fibrosis. To understand the role of Rho GTPase signaling in TGFβ-induced myofibroblast differentiation of MSC, we generated a novel MSC line and descendants of it lacking functional Rho GTPases and Rho GTPase signaling components. Unexpectedly, our data revealed that Rho GTPase signaling is required for TGFβ-induced expression of αSMA, but not of collagen I α1 (col1a1). While loss of RhoA and Cdc42 reduced αSMA expression, ablation of the Rac1 gene had the opposite effect. Although actin polymerization and MRTFa were crucial for TGFβ-induced αSMA expression, neither Arp2/3 dependent actin polymerization nor cofilin dependent severing and depolymerization of F-actin were required. Instead, F-actin levels were dependent on cell contraction and TGFβ-induced actin polymerisation correlated with increased cell contraction mediated by RhoA and Cdc42. Finally, we observed impaired collagen I secretion in MSC lacking RhoA or Cdc42. These data give novel molecular insights into the role of Rho GTPases in TGFβ signaling and have implications for our understanding of MSC function in fibrosis. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

Nonlinear Analysis for the Crack Control of SMA Smart Concrete Beam Based on a Bidirectional B-Spline QR Method

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Yan Li

2018-01-01

Full Text Available A bidirectional B-spline QR method (BB-sQRM for the study on the crack control of the reinforced concrete (RC beam embedded with shape memory alloy (SMA wires is presented. In the proposed method, the discretization is performed with a set of spline nodes in two directions of the plane model, and structural displacement fields are constructed by the linear combination of the products of cubic B-spline interpolation functions. To derive the elastoplastic stiffness equation of the RC beam, an explicit form is utilized to express the elastoplastic constitutive law of concrete materials. The proposed model is compared with the ANSYS model in several numerical examples. The results not only show that the solutions given by the BB-sQRM are very close to those given by the finite element method (FEM but also prove the high efficiency and low computational cost of the BB-sQRM. Meanwhile, the five parameters, such as depth-span ratio, thickness of concrete cover, reinforcement ratio, prestrain, and eccentricity of SMA wires, are investigated to learn their effects on the crack control. The results show that depth-span ratio of RC beams and prestrain and eccentricity of SMA wires have a significant influence on the control performance of beam cracks.

PENGARUH SUPERVISI AKADEMIK, KOMPETENSI GURU DAN KEDISIPLINAN TERHADAP KINERJA GURU SMA NEGERI 3 SLAWI KABUPATEN TEGAL

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Sussono Hadi

2009-09-01

Full Text Available This research is aimed at finding out the impact of academic supervision, teacher’s competence, and discipline towards the performance of teachers of SMA Negeri 3 Slawi, Tegal. This research used survey method. The data was collected using questionnaire and observation. There were 52 teachers as respondents. The data analysis used was percentage, multiple linear regression, F test and t test. The finding was : 1 academic supervision, teacher’s competence and discipline of SMA 3 Slawi teachers were very good, 2 academic supervision, teacher’s competence, and discipline together had impact towards teachers’ performance, 3 academic supervision, teacher’s competence, and discipline separately had impact on teachers’ performance, and 4 discipline had the strongest impact towards teachers’ performance. With this result it is suggested that the Diknas (the regential ministry of education intensify the academic supervision, continually developing teacher’s competence, and enforcing discipline on teachers and schools. Key words: academic supervision, competence, discipline, teacher’s performance

A 3D Printed Implantable Device for Voiding the Bladder Using Shape Memory Alloy (SMA) Actuators.

Science.gov (United States)

Hassani, Faezeh Arab; Peh, Wendy Yen Xian; Gammad, Gil Gerald Lasam; Mogan, Roshini Priya; Ng, Tze Kiat; Kuo, Tricia Li Chuen; Ng, Lay Guat; Luu, Percy; Yen, Shih-Cheng; Lee, Chengkuo

2017-11-01

Underactive bladder or detrusor underactivity (DU) is defined as a reduction of contraction strength or duration of the bladder wall. Despite the serious healthcare implications of DU, there are limited solutions for affected individuals. A flexible 3D printed implantable device driven by shape memory alloys (SMA) actuators is presented here for the first time to physically contract the bladder to restore voluntary control of the bladder for individuals suffering from DU. This approach is used initially in benchtop experiments with a rubber balloon acting as a model for the rat bladder to verify its potential for voiding, and that the operating temperatures are safe for the eventual implantation of the device in a rat. The device is then implanted and tested on an anesthetized rat, and a voiding volume of more than 8% is successfully achieved for the SMA-based device without any surgical intervention or drug injection to relax the external sphincter.

Usefulness of multidetector-row CT (MDCT) for the diagnosis of non-occlusive mesenteric ischemia (NOMI): Assessment of morphology and diameter of the superior mesenteric artery (SMA) on multi-planar reconstructed (MPR) images

International Nuclear Information System (INIS)

Woodhams, Reiko; Nishimaki, Hiroshi; Fujii, Kaoru; Kakita, Satoko; Hayakawa, Kazushige

2010-01-01

Objective: The purpose of this study was to assess the efficacy of multidetector-row CT (MDCT) for the diagnosis of non-occlusive mesenteric ischemia (NOMI) by analyzing morphology and diameter of superior mesenteric artery (SMA). We assessed whether MDCT was as useful as angiography for the diagnosis of NOMI. Materials and methods: Four patients who were diagnosed with NOMI were retrospectively analyzed. All patients had 8-row MDCT followed by laparotomy. Two of them underwent angiography after MDCT. The morphology and diameter of SMA of these cases was analyzed on multi-planar reconstructed (MPR) images. The mean diameter of SMA of NOMI cases was compared to that of 13 control cases. Results: MPR images of all NOMI cases showed irregular narrowing of the SMA, spasm of the arcades of SMA, and poor demonstration of intramural vessels. MPR images of two patients who had angiography were concordant with their angiograms. The mean diameter of SMA of NOMI patients was 3.4 ± 1.1 mm, which was statistically smaller than that of 13 control patients, 6.0 ± 1.5 mm (P < 0.05, Wilcoxon rank sum tests). Conclusion: Angiography has been recognized essential for the diagnosis of NOMI. This study shows the possibility of MDCT to be an equivalently useful modality compared to angiography for the diagnosis of NOMI by interpreting morphologic appearance and diameter of SMA. Introduction of MDCT in the decision tree of NOMI treatment may bring the benefit of prompt diagnosis and subsequent early and efficient initiation of therapy, which may improve the mortality.

Recent developments on SMA actuators: predicting the actuation fatigue life for variable loading schemes

Science.gov (United States)

Wheeler, Robert W.; Lagoudas, Dimitris C.

2017-04-01

Shape memory alloys (SMAs), due to their ability to repeatably recover substantial deformations under applied mechanical loading, have the potential to impact the aerospace, automotive, biomedical, and energy industries as weight and volume saving replacements for conventional actuators. While numerous applications of SMA actuators have been flight tested and can be found in industrial applications, these actuators are generally limited to non-critical components, are not widely implemented and frequently one-off designs, and are generally overdesigned due to a lack of understanding of the effect of the loading path on the fatigue life and the lack of an accurate method for predicting actuator lifetimes. In recent years, multiple research efforts have increased our understanding of the actuation fatigue process of SMAs. These advances can be utilized to predict the fatigue lives and failure loads in SMA actuators. Additionally, these prediction methods can be implemented in order to intelligently design actuators in accordance with their fatigue and failure limits. In the following paper, both simple and complex thermomechanical loading paths have been considered. Experimental data was utilized from two material systems: equiatomic Nickel-Titanium and Nickelrich Nickel-Titanium.

Representasi Matematis Siswa SMA dalam Memecahkan Masalah Persamaan Kuadrat Ditinjau dari Perbedaan Gender

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Moh. Nasrul Fuad

2016-12-01

Full Text Available Penelitian ini merupakan penelitian deskriptif kualitatif yang bertujuan untuk mendeskripsikan secara lengkap representasi matematis siswa SMA dalam memecahkan masalah persamaan kuadrat ditinjau dari perbedaan gender. Subjek penelitian terdiri dari dua siswa SMA Negeri 3 Kediri kelas 10 pada tahun pelajaran 2015/2016, yaitu satu siswa laki-laki dan satu siswa perempuan. Tahap penelitian dimulai dengan pemilihan subjek penelitian yang ditentukan berdasarkan gender dan hasil tes kemampuan matematika yang setara. Setelah terpilih subjek kemudian dilanjutkan dengan pemberian tugas pemecahan masalah persamaan kuadrat dan wawancara. Keabsahan data dilakukan dengan menggunakan triangulasi waktu yaitu pemberian tugas pemecahan masalah persamaan kuadrat yang setara pada waktu yang berbeda. Hasil penelitian ini berupa deskripsi matematis dari siswa SMA laki-laki dan perempuan dalam memecahkan masalah persamaan kuadrat untuk setiap tahap pemecahan masalah menurut tahapan Polya. Representasi matematis dari siswa SMA laki-laki yaitu : Pada tahap memahami masalah, dari apa yang diketahui representasi matematis yang dihasilkan siswa berupa kombinasi antara teks tertulis dan simbol. Sedangkan dari apa yang ditanyakan, representasi matematis yang dihasilkan siswa yaitu berupa simbol dan juga teks tertulis. Pada tahap menyusun rencana pemecahan masalah, representasi matematis yang dihasilkan siswa berupa persamaan matematik dan juga kata-kata secara lisan. Pada tahap melaksanakan rencana pemecahan masalah, langkah – langkah pemecahan masalah direpresentasikan oleh siswa kedalam bentuk persamaan matematik dan simbol aljabar. Siswa menginterpretasi hasil penyelesaian masalah dengan menggunakan representasi berupa teks tertulis. Pada tahap memeriksa kembali penyelesaian masalah siswa tidak memiliki representasi.  Sedangkan representasi matematis dari siswa SMA perempuan yaitu : Pada tahap memahami masalah dari apa yang diketahui representasi matematis yang

Hubungan Facebook Addiction Disorder (Fad) dengan Perilaku Asertif Remaja di SMA Kristen 1 Tomohon

OpenAIRE

Polii, Gloria Gratia; Bidjuni, Hendro; Wowiling, Ferdinand

2014-01-01

: Facebook addiction berarti menghabiskan jumlah waktu yang berlebihan di facebook. Facebook merupakan situs jejaring sosial yang mudah digunakan, dan yang paling penting adalah mempunyai efek mencandu. Secara psikologis, dampak negatif kecanduan facebook dapat dibagi atas: Pribadi yang anti sosial dan Dualisme kepribadian. Tujuan penelitian ini untuk mengetahui hubungan Facebook Addiction Disorder (FAD) dengan Perilaku Asertif Remaja di SMA Kristen 1 Tomohon. Desain penelitian ini dilaksanak...

Multifractional microablative laser combined with spacially modulated ablative (SMA) technology for facial skin rejuvenation.

Science.gov (United States)

Hersant, Barbara; SidAhmed-Mezi, Mounia; Chossat, Adrien; Meningaud, Jean Paul

2017-01-01

Due to the increasing demand for aesthetic procedures, especially facial aesthetic surgery, a new laser technology has been developed for facial skin rejuvenation and wrinkle treatment. The aim of this study was to objectively and subjectively assess the clinical efficacy and safety of Erbium:YAG laser combined with Spatially Modulated Ablation (Er:YAG + SMA) on facial skin rejuvenation. Patients with Fitzpatrick skin type's I-IV were prospectively included. Inclusion criteria consisted of having wrinkles and irregular skin texture. All patients underwent two Er:YAG + SMA sessions (1 month apart) to stimulate tissue regeneration. Er:YAG laser emits wavelength at 2,940 nm and when combined with SMA, a resonance effect is produced in the dermis to promote tissue regeneration. Facial skin elasticity and firmness were objectively assessed by Cutometer at baseline and month 6 (M6). Aesthetic improvement was qualitatively assessed using digital photographs. Patient satisfaction with regard to their facial appearance was self-assessed using the validated FACE-Q scale and the patient-perceived age VAS scale at baseline, M1, and M6. Side effects were investigated after each session. Thirty-four patients were included, 50% (18 patients) had Fitzpatrick skin type III and 41% (14 patients) were smokers. Skin elasticity indices were significantly improved: from 0.335 ± 0.015 at baseline to 0.387 ± 0.021 at M6 (P = 0.05*) for R5 (net elasticity). Skin firmness was assessed through R7 (biological elasticity) and R6 (viscoelastic ratio) at baseline and M6: a significant increase from 0.235 ± 0.01 to 0.2709 ± 0.009 (P technology offers an effective and safe treatment alternative for facial skin rejuvenation. It reduces the recovery time compared to conventional lasers such as carbon dioxide laser. Lasers Surg. Med. 49:78-83, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

KEMAMPUAN PROFESIONAL GURU BIOLOGI DALAM MEMAHAMI DAN MERANCANG MODEL PEMBELAJARAN KONSERVASI BIODIVERSITAS DI SMA

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Suroso Mukti Leksono

2013-11-01

Full Text Available Abstrak: Tujuan penelitian ini adalah untuk mengetahui penguasaan konsep konservasi biodiversitas guru biologi dan cara mengajarkannya. Penelitian ini menggunakan metode deskriptif dengan menggunakan angket pada 31 guru SMA/MA di Kota/Kab Serang. Hasil penelitian menunjukkan bahwa 52% guru telah memahami konsep biodiversitas, namun hanya 3% yang memahami konsep konservasi. Model yang digunakan guru dalam mengajarkan konservasi biodiversitas, 58% menggunakan observasi, 45% diskusi, 23% ceramah dan 16% tanya jawab. Untuk tingkat kesukaran, 87% guru beranggapan mudah memahami materi konservasi biodiversitas dan 81% beranggapan mudah mengajarkannya dibandingkan dengan materi IPA lainnya. Guru-guru selama ini hanya 6% saja yang memperoleh pengetahuan tentang konservasi biodiversitas pada saat pelatihan. Oleh sebab itu diperlukan pelatihan-pelatihan melalui Continuing Professional Development (CPD. Kata Kunci: guru profesional, konservasi biodiversitas, continuing professional development (CPD BIOLOGY TEACHERS’ PROFESSIONAL ABILITY IN UNDERSTANDING AND DESIGNING INSTRUCTION ON BIODIVERSITY CONSERVATION IN SMA Abstract: The purpose of this study was to gain the knowledge about biology teachers’ concept mastery on biodiversity conservation as well as how to teach it. This study used descriptive methods with the questionnaires to 31 respondents of SMA/MA in Kota/KabSerang. The research result showed that 52% respondents had mastered the biodiversity concept. However, only 3% of respondents had fully mastered biodiversity conservation. In addition, for the teaching methods 58% respondents used observation, 45% respondents used discussion, 23% respondents used lecturing and 16% respondents used an interactive method. Moreover, for the difficulty level, 87% of respondents argued that it was easy to master the biodiversity conservation materials and 81% said that it was easier to teach the concept than other concepts. Only 6% of the teachers had gained

FAKTOR-FAKTOR YANG MEMPENGARUHI DERAJAT MIOPIA PADA REMAJA (STUDI DI SMA NEGERI 2 TEMANGGUNG KABUPATEN TEMANGGUNG

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Anisa Sofiani

2016-04-01

Full Text Available Miopia sebagai kelainan refraksi menjadi penyebab terbanyak gangguan penglihatan di dunia hingga diestimasikan separuh dari penduduk dunia menderita miopia pada tahun 2020. Segala golongan usia dapat mengalami miopia, terutama pada remaja. Jawa tengah menduduki peringkat ke 6 untuk masalah miopia, dan remaja yang menderita miopia di kabupaten Temanggung khususnya SMA N 2 Temanggung diperkirakan meningkat tiap tahunnya. Penelitian ini termasuk dalam penelitian explanatory research dengan pendekatan cross sectional. Populasi berjumlah 720 siswa, sampel 92 siswa SMA N 2 Temanggung. Hasil penelitian ini adalah terdapat hubungan antara jarak baca (p=0,042, intensitas gadget (p=0,049, intensitas jalan kaki outdoor (0,004, dan intensitas olahraga outdoor (p=0,017 dengan derajat miopia remaja. Dan tidak ada hubungan dengan jenis kelamin, asupan vitamin A, lama membaca, penerangan, posisi membaca, penggunaan gadget /hari, pekerjaan, pendapatan orang tua, keturunan, intensitas rekreasi dan hobi. Faktor terkuat adalah olahraga outdoor (p=0,005 dan OR=17,468. Anjuran untuk penelitian selanjutnya adalah dalam penghitungan asupan Vitamin A apakah mempengaruhi peningkatan dioptri miopia agar memperhatikan cara pengolahan makanan. Kategori untuk variabel penggunaan gadget juga perlu ditambahkan. Myopia as refractive error will be the most common cause of visual impairment over the world until half of the world's populations are suffer from myopia in 2020. All of age groups can get it, especially in adolescents. Central Java’s ranked is sixth for the problems of myopia, and adolescents who suffer the myopia in Temanggung regency in particular SMA N 2 Temanggung is expected to increase each year. This study was explanatory research with cross sectional approach. The population were 720 students, with 92 samples students of SMA N 2 Temanggung. The Results, there were a relationship between reading distance (p=0.042, the intensity of the gadget (p=0.049, the

The Development of Learning Model Based on Problem Solving to Construct High-Order Thinking Skill on the Learning Mathematics of 11th Grade in SMA/MA

Science.gov (United States)

Syahputra, Edi; Surya, Edy

2017-01-01

This paper is a summary study of team Postgraduate on 11th grade. The objective of this study is to develop a learning model based on problem solving which can construct high-order thinking on the learning mathematics in SMA/MA. The subject of dissemination consists of Students of 11th grade in SMA/MA in 3 kabupaten/kota in North Sumatera, namely:…

SU-F-J-10: Sliding Mode Control of a SMA Actuated Active Flexible Needle for Medical Procedures

International Nuclear Information System (INIS)

Podder, T

2016-01-01

Purpose: In medical interventional procedures such as brachytherapy, ablative therapies and biopsy precise steering and accurate placement of needles are very important for anatomical obstacle avoidance and accurate targeting. This study presents the efficacy of a sliding mode controller for Shape Memory Alloy (SMA) actuated flexible needle for medical procedures. Methods: Second order system dynamics of the SMA actuated active flexible needle was used for deriving the sliding mode control equations. Both proportional-integral-derivative (PID) and adaptive PID sliding mode control (APIDSMC) algorithms were developed and implemented. The flexible needle was attached at the end of a 6 DOF robotic system. Through LabView programming environment, the control commands were generated using the PID and APIDSMC algorithms. Experiments with artificial tissue mimicking phantom were performed to evaluate the performance of the controller. The actual needle tip position was obtained using an electromagnetic (EM) tracking sensor (Aurora, NDI, waterloo, Canada) at a sampling period of 1ms. During experiment, external disturbances were created applying force and thermal shock to investigate the robustness of the controllers. Results: The root mean square error (RMSE) values for APIDSMC and PID controllers were 0.75 mm and 0.92 mm, respectively, for sinusoidal reference input. In the presence of external disturbances, the APIDSMC controller showed much smoother and less overshooting response compared to that of the PID controller. Conclusion: Performance of the APIDSMC was superior to the PID controller. The APIDSMC was proved to be more effective controller in compensating the SMA uncertainties and external disturbances with clinically acceptable thresholds.

SU-F-J-10: Sliding Mode Control of a SMA Actuated Active Flexible Needle for Medical Procedures

Energy Technology Data Exchange (ETDEWEB)

Podder, T [University Hospitals Case Medical Center, Cleveland, OH (United States)

2016-06-15

Purpose: In medical interventional procedures such as brachytherapy, ablative therapies and biopsy precise steering and accurate placement of needles are very important for anatomical obstacle avoidance and accurate targeting. This study presents the efficacy of a sliding mode controller for Shape Memory Alloy (SMA) actuated flexible needle for medical procedures. Methods: Second order system dynamics of the SMA actuated active flexible needle was used for deriving the sliding mode control equations. Both proportional-integral-derivative (PID) and adaptive PID sliding mode control (APIDSMC) algorithms were developed and implemented. The flexible needle was attached at the end of a 6 DOF robotic system. Through LabView programming environment, the control commands were generated using the PID and APIDSMC algorithms. Experiments with artificial tissue mimicking phantom were performed to evaluate the performance of the controller. The actual needle tip position was obtained using an electromagnetic (EM) tracking sensor (Aurora, NDI, waterloo, Canada) at a sampling period of 1ms. During experiment, external disturbances were created applying force and thermal shock to investigate the robustness of the controllers. Results: The root mean square error (RMSE) values for APIDSMC and PID controllers were 0.75 mm and 0.92 mm, respectively, for sinusoidal reference input. In the presence of external disturbances, the APIDSMC controller showed much smoother and less overshooting response compared to that of the PID controller. Conclusion: Performance of the APIDSMC was superior to the PID controller. The APIDSMC was proved to be more effective controller in compensating the SMA uncertainties and external disturbances with clinically acceptable thresholds.

Analisis Kemampuan Berpikir Matematis Siswa SMA kota Sorong terhadap Butir Soal dengan Graded Response Model

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Muhammad Syahrul Kahar

2017-06-01

Full Text Available This research aims to know the level of mathematical thinking ability of students by using scored model Graded Response Model (GRM. The subject here is the students of Class XI IPA 1 SMA Negeri 3 Sorong the 2016/2017 academic year, which amounted to 38 students with 22 students are male and 16 female students. This research is a descriptive research experiment. The results of this study indicate that the scored model GRM is effective in analyzing the ability of mathematical thinking of students. The effectiveness is shown an increase in student learning outcomes grade XI IPA 1 SMA Negeri 3 Kota Sorong, where the average grade results visible increase of 56.7 until 78, and the value of the completeness students improved significantly, and student learning outcomes were shown in graded contents relevance criteria students with score 4 there are 18 students (47.37%, while the relevance of the contents with a score of 1 there are 4 students (10.53%. From the criteria of completeness students who achieve complete answers by a score of 4, there are 1 students (2.64%, and the answers are far from finished with a score of 1 there were 7 students (19.52%. Then to organizing criteria, students are working on a very systematic, there are 8 students (21.05%, and organizing with not systematically there are 10 students (26.32%. Penelitian ini bertujuan untuk mengetahui tingkat kemampuan berpikir matematis siswa dengan menggunakan model penyekoran Graded Response Model (GRM. Subjek penelitian disini adalah siswa kelas XI IPA 1 SMA Negeri 3 Kota Sorong tahun ajaran 2016/2017, yang berjumlah 38 siswa dengan 22 siswa laki-laki dan 16 siswa perempuan. Penelitian ini adalah penelitian eksperimen yang bersifat Deskriptif. Hasil penelitian ini menunjukkan bahwa model penyekoran GRM ini efektif dalam menganalisis kemampuan berpikir matematis siswa. Keefektifan tersebut terlihat adanya peningkatan hasil belajar siswa kelas XI IPA 1 SMA Negeri 3 Kota Sorong, dimana

Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.

Science.gov (United States)

Iyer, Chitra C; McGovern, Vicki L; Murray, Jason D; Gombash, Sara E; Zaworski, Phillip G; Foust, Kevin D; Janssen, Paul M L; Burghes, Arthur H M

2015-11-01

Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder characterized by loss of lower motor neurons. SMA is caused by deletion or mutation of the Survival Motor Neuron 1 (SMN1) gene and retention of the SMN2 gene. The loss of SMN1 results in reduced levels of the SMN protein. SMN levels appear to be particularly important in motor neurons; however SMN levels above that produced by two copies of SMN2 have been suggested to be important in muscle. Studying the spatial requirement of SMN is important in both understanding how SMN deficiency causes SMA and in the development of effective therapies. Using Myf5-Cre, a muscle-specific Cre driver, and the Cre-loxP recombination system, we deleted mouse Smn in the muscle of mice with SMN2 and SMNΔ7 transgenes in the background, thus providing low level of SMN in the muscle. As a reciprocal experiment, we restored normal levels of SMN in the muscle with low SMN levels in all other tissues. We observed that decreasing SMN in the muscle has no phenotypic effect. This was corroborated by muscle physiology studies with twitch force, tetanic and eccentric contraction all being normal. In addition, electrocardiogram and muscle fiber size distribution were also normal. Replacement of Smn in muscle did not rescue SMA mice. Thus the muscle does not appear to require high levels of SMN above what is produced by two copies of SMN2 (and SMNΔ7). © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Design, fabrication, and testing of a SMA hybrid composite jet engine chevron

Science.gov (United States)

Turner, Travis L.; Cabell, Randolph H.; Cano, Roberto J.; Fleming, Gary A.

2006-01-01

Control of jet noise continues to be an important research topic. Exhaust nozzle chevrons have been shown to reduce jet noise, but parametric effects are not well understood. Additionally, thrust loss due to chevrons at cruise suggests significant benefit from deployable chevrons. The focus of this study is development of an active chevron concept for the primary purpose of parametric studies for jet noise reduction in the laboratory and technology development to leverage for full scale systems. The active chevron concept employed in this work consists of a laminated composite structure with embedded shape memory alloy (SMA) actuators, termed a SMA hybrid composite (SMAHC). The actuators are embedded on one side of the middle surface such that thermal excitation generates a moment and deflects the structure. A brief description of the chevron design is given followed by details of the fabrication approach. Results from bench top tests are presented and correlated with numerical predictions from a model for such structures that was recently implemented in MSC.Nastran and ABAQUS. Excellent performance and agreement with predictions is demonstrated. Results from tests in a representative flow environment are also presented. Excellent performance is again achieved for both open- and closed-loop tests, the latter demonstrating control to a specified immersion into the flow. The actuation authority and immersion performance is shown to be relatively insensitive to nozzle pressure ratio (NPR). Very repeatable immersion control with modest power requirements is demonstrated.

Investigation on the Cyclic Response of Superelastic Shape Memory Alloy (SMA Slit Damper Devices Simulated by Quasi-Static Finite Element (FE Analyses

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Jong Wan Hu

2014-02-01

Full Text Available In this paper, the superelastic shape memory alloy (SMA slit damper system as an alternative design approach for steel structures is intended to be evaluated with respect to inelastic behavior simulated by refined finite element (FE analyses. Although the steel slit dampers conventionally used for aseismic design are able to dissipate a considerable amount of energy generated by the plastic yielding of the base materials, large permanent deformation may occur in the entire structure. After strong seismic events, extra damage repair costs are required to restore the original configuration and to replace defective devices with new ones. Innovative slit dampers fabricated by superelastic SMAs that automatically recover their initial conditions only by the removal of stresses without heat treatment are introduced with a view toward mitigating the problem of permanent deformation. The cyclically tested FE models are calibrated to experimental results for the purpose of predicting accurate behavior. This study also focuses on the material constitutive model that is able to reproduce the inherent behavior of superelastic SMA materials by taking phase transformation between austenite and martensite into consideration. The responses of SMA slit dampers are compared to those of steel slit dampers. Axial stress and strain components are also investigated on the FE models under cyclic loading in an effort to validate the adequacy of FE modeling and then to compare between two slit damper systems. It can be shown that SMA slit dampers exhibit many structural advantages in terms of ultimate strength, moderate energy dissipation and recentering capability.

NRC Information No. 89-43: Permanent deformation of torque switch helical springs in Limitorque SMA-type motor operators

International Nuclear Information System (INIS)

Rossi, C.E.

1992-01-01

Problems with the helical springs were discovered during a series of dynamic tests that were conducted with a motor-operated wedge-gate valve from the decommissioned Shippingport Atomic Power Station (Shippingport). The valve was installed in a portion of the piping system that had been modified to simulate the stiffness of a typical US piping system. The valve was 30 years old and had its original Limitorque SMA-type motor operator. One of the main objectives of these tests was to determine the operating capability of the valve when subjected to simultaneous internal hydraulic and seismic loadings. This was typically accomplished by operating the valve to achieve maximum hydraulic loading during maximum seismic loading. During testing, an operability problem with the valve motor operator occurred. The design of the SMA-type motor operator is such that the torque switch helical spring is in its most compressed condition when the valve is closed. Thus, a normally closed valve is more likely to experience permanent deformation of the helical torque spring. A review of the Shippingport records indicated that both of these valves had been used as normally closed valves at Shippingport. Thus, normally closed, safety-related valves with Limitorque SMA-type motor operators may not accomplish their intended safety-related function because the original torque switch setting may result in lower output torque caused by the permanent deformation of their torque switch helical springs

New open cluster candidates discovered in the XSTPS-GAC survey

Science.gov (United States)

Guo, Jin-Cheng; Zhang, Hua-Wei; Zhang, Hui-Hua; Liu, Xiao-Wei; Yuan, Hai-Bo; Huang, Yang; Wang, Song; Chen, Li; Zhao, Hai-Bin; Liu, Ji-Feng; Chen, Bing-Qiu; Xiang, Mao-Sheng; Tian, Zhi-Jia; Huo, Zhi-Ying; Wang, Chun

2018-03-01

The Xuyi Schmidt Telescope Photometric Survey of the Galactic Anti-center (XSTPS-GAC) is a photometric sky survey that covers nearly 6000 deg2 towards the Galactic Anti-center (GAC) in the g, r, i bands. Half of its survey field is located on the Galactic Anti-center disk, which makes XSTPS-GAC highly suitable to search for new open clusters in the GAC region. In this paper, we report new open cluster candidates discovered in this survey, as well as properties of these open cluster candidates, such as age, distance and reddening, derived by isochrone fitting in the color-magnitude diagram (CMD). These open cluster candidates are stellar density peaks detected in the star density maps by applying the method from Koposov et al. Each candidate is inspected in terms of its true color image composed from three XSTPS-GAC band images. Then its CMD is checked, in order to identify whether the central region stars have a clear isochrone-like trend differing from background stars. The parameters derived from isochrone fitting for these candidates are mainly based on three band photometry of XSTPS-GAC. Moreover, when these new candidates are able to be seen clearly in 2MASS data, their parameters are also derived based on the 2MASS (J – H, J) CMD. There are a total of 320 known open clusters rediscovered and 24 new open cluster candidates discovered in this work. Furthermore, the parameters of these new candidates, as well as another 11 previously known open clusters, are properly determined for the first time.

Pose de la première pierre du bâtiment SMA18 du Cern

CERN Multimedia

CERN Press Office. Geneva

1999-01-01

On 30 April 1999, Jean Pépin, Sénateur for the Department of the Ain and President of the Conseil Général, and Professor Luciano Maiani the Director-General of CERN will lay the foundation stone of Building SMA18, financed by the Department of the Ain in the framework of France's special contribution to CERN's Large Hadron Collider (LHC) project.

A phenomenological SMA model for combined axial–torsional proportional/non-proportional loading conditions

International Nuclear Information System (INIS)

Bodaghi, M.; Damanpack, A.R.; Aghdam, M.M.; Shakeri, M.

2013-01-01

In this paper, a simple and robust phenomenological model for shape memory alloys (SMAs) is proposed to simulate main features of SMAs under uniaxial as well as biaxial combined axial–torsional proportional/non-proportional loadings. The constitutive model for polycrystalline SMAs is developed within the framework of continuum thermodynamics of irreversible processes. The model nominates the volume fractions of self-accommodated and oriented martensite as scalar internal variables and the preferred direction of oriented martensitic variants as directional internal variable. An algorithm is introduced to develop explicit relationships for the thermo-mechanical behavior of SMAs under uniaxial and biaxial combined axial–torsional proportional/non-proportional loading conditions and also thermal loading. It is shown that the model is able to simulate main aspects of SMAs including self-accommodation, martensitic transformation, orientation and reorientation of martensite, shape memory effect, ferro-elasticity and pseudo-elasticity. A description of the time-discrete counterpart of the proposed SMA model is presented. Experimental results of uniaxial tension and biaxial combined tension–torsion non-proportional tests are simulated and a good qualitative correlation between numerical and experimental responses is achieved. Due to simplicity and accuracy, the model is expected to be used in the future studies dealing with the analysis of SMA devices in which two stress components including one normal and one shear stress are dominant

Comparative Transcriptome Analysis Reveals That Lactose Acts as an Inducer and Provides Proper Carbon Sources for Enhancing Exopolysaccharide Yield in the Deep-Sea Bacterium Zunongwangia profunda SM-A87

Science.gov (United States)

Qin, Qi-Long; Li, Yi; Sun, Mei-Ling; Rong, Jin-Cheng; Liu, Sheng-Bo; Chen, Xiu-Lan; Su, Hai-Nan; Zhou, Bai-Cheng; Xie, Bin-Bin; Zhang, Yu-Zhong; Zhang, Xi-Ying

2015-01-01

Many marine bacteria secrete exopolysaccharides (EPSs) that have important ecological and physiological functions. Numerous nutritional and environmental factors influence bacterial EPS production. However, the regulatory mechanisms of EPS production are poorly understood. The deep-sea Bacteroidetes bacterium Zunongwangia profunda SM-A87 can produce high quantities of EPS, and its EPS production is enhanced significantly by lactose. Here, we studied the reasons behind the significant advantage that lactose has over other carbon sources in EPS production in SM-A87. RNA-seq technologies were used to study lactose-regulated genes in SM-A87. The expression level of genes within the EPS gene cluster was up-regulated when lactose was added. Supplement of lactose also influenced the expression of genes located outside the EPS gene cluster that are also involved in EPS biosynthesis. The major glycosyl components of SM-A87 EPS are mannose, glucose and galactose. Genomic metabolic pathway analyses showed that the EPS precursor GDP-mannose can be synthesized from glucose, while the precursor UDP-glucose must be synthesized from galactose. Lactose can provide glucose and galactose simultaneously and prevent glucose inhibition. Lactose can also greatly stimulate the growth of SM-A87. Taken together, lactose acts not only as an inducer but also as a carbohydrate source for EPS production. This research broadens our knowledge of the regulation of EPS production in marine bacteria. PMID:25679965

HUBUNGAN PENGETAHUAN REMAJA TENTANG KESEHATAN REPRODUKSIDENGAN SIKAP TERHADAP SEKS BEBAS DI SMA NEGERI 1 SEDAYU BANTUL YOGYAKARTA

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Umi Latifah

2015-08-01

Full Text Available Background:Adolescence isa periodof transition fromchildhood toadulthood.Adolescence tendtowantto learnnew thingssotheyappear towant to be doublebehavior, one of which is illicit sex. Based onpreliminary studiesconducted inSMAN1Sedayuobtained informationsome students donot understandthe impact of freesex.Theyalso lackknowledgeabout reproductive health. Objectives:Thepurposeof thisstudi todeterminetherelationshipbetween the level of knowledgeaboutadolescent reproductivehealthattitudes towardsex inSMA N 1SedayuBantul Yogyakarta.Methods : The method in this research is descriptive analytic with cross sectional approach.Sampleswere takenwithquotasampling technique in which168 students aged16-18years inSMAN1Sedayu.The research instrument was a questionnaireand the results wereanalyzedby Kendall Taucorrelation formula. Results : The level of knowledge about adolescent reproductive health inSMAN1SedayuBantulmostlywellas78students(46.4%.Attitudes towardsex inSMA 1SedayuBantul Yogyakarta Sedayumostlypositiveasmanyas133 students(79.2%. Theresultsof thecorrelation test of Kendall Tauobtained p-valueof 0,000<(0,05.Conclusion : There is a significant relationship between the level of knowledge about adolescentreproductivehealthattitudes toward sex inSMAN1SedayuBantul, Yogyakarta.

Efektifitas Layanan Bimbingan dan Konseling Untuk Mengatasi Masalah Menyontek dan Pengaruhnya terhadap Prestasi Belajar Siswa SMA Negeri 11 Ambon

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Purwatib

2018-01-01

Full Text Available The problem of cheating for learners is not something new in the world of school. When school programs begin to enter the stage of assessment, then there are also various behavior patterns of learners to prepare themselves to face a test or test. In fact, in schools such as SMA Negeri 11 Ambon there are some students of class X IPS do cheat behavior at the time of replication take place. The research was conducted in SMA Negeri 11 Ambon, the result of the research showed that there were differences of learners behavior, before and after the students got guidance and counseling service. Of the 40 respondents who originally cheated, after being given guidance almost all declared no and have abandoned the attitude of cheating.

Teka-teki Unsur Kimia sebagai Media Pembelajaran Kimia Interaktif bagi siswa SMA Kelas X Berbasis Android

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Isvandiari Fitri Utami

2016-01-01

Full Text Available Unsur kimia yang terdiri dari banyak unsur sering membuat siswa malas dengan mata pelajaran kimia khususnya dalam hal menghafal sistem periodik unsur kimia. Terkait dengan masalah ini, salah satu solusi yang ditawarkan adalah melalui media pembelajaran. Salah satu cara untuk membantu siswa melalui media pembelajaran dapat dilakukan dengan memanfaaatkan teknologi smartphone yang telah banyak dimiliki. Melihat banyaknya siswa yang telah menggunakan smartphone setiap harinya memungkinkan untuk memadukan kedua hal tersebut, sehingga siswa tidak hanya menggunakan smartphone sebagai sarana komunikasi, sosial media dan bermain game, tetapi dapat dialihkan menjadi sebuah inovasi positif dalam hal edukasi untuk menunjang sistem belajar yang interaktif. Tujuan dari penelitian ini adalah membuat aplikasi teka-teki unsur kimia sebagai media pembelajaran kimia interaktif bagi siswa SMA kelas X berbasis android. Salah satu manfaat dari penelitian ini adalah hasil penelitian dapat dijadikan rujukan bagi perkembangan dunia teknologi dan berguna juga untuk menjadi referensi bagi mahasiswa yang melakukan pengembangan produk teknologi khususnya mengenai media pembelajaran berbasis android. Dalam melakukan penelitian ini, aplikasi dibangun dengan menggunakan metode pengembangan multimedia development life cycle, data dan informasi mengenai unsur- unsur kimia dalam sistem periodik unsur diperoleh dari buku materi kimia SMA kelas X berdasarkan kurikulum 2006, beberapa jurnal, dan dari pengajar kimia untuk materi SMA kelas X secara langsung. Pada tahapan implementasi, program dibuat dengan drag and drop serta menggunakan bahasa pemrograman Javascript. Pengujian yang dilakukan pada aplikasi adalah dengan menggunakan metode whitebox. Berdasarkan hasil pengujian yang dilakukan pada aplikasi teka-teki unsur kimia sebagai media pembelajaran kimia interaktif berbasis aplikasi android, aplikasi sudah mampu berjalan cukup maksimal. Hasil pengujian mampu menampilkan

COMPARING THE USE OF FIVE-PACKAGE OF MATH IN THE 2011 NATIONAL EXAMINATION BETWEEN SMA AND MADRASAH ALIYAH: A CASE STUDY IN JAKARTA

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Wardani Rahayu

2014-03-01

Full Text Available This study aims to compare five question packages used in the 2011 National Examination, specifically for Maths for Social Studies subject between public senior high school (SMA and Islamic senior high school (MA in Jakarta. It employed simple random sampling as its data collection technique. The independent variables used were the category of high schools and the Five Question Packages used in the National Examination. The schools were divided into two: regular senior high school (SMA and Islamic senior high school or Madrasah Aliyah (MA. The packages chosen to be analyzed were package number: 12, 25, 39, 46 and 54. The data was analyzed by two-factor ANOVA for its 11 Differential Item Function (DIF and 29 non Differential Item Function (non-DIF items. The items used for this study are the items that fit the three-parameter logistic model. This study found that no difference between the scores on both the DIF and non-DIF items in either for SMA or Ma is found.

SMA Diagnosis: Detection of SMN1 Deletion with Real-Time mCOP-PCR System Using Fresh Blood DNA.

Science.gov (United States)

Niba, Emma Tabe Eko; Ar Rochmah, Mawaddah; Harahap, Nur Imma Fatimah; Awano, Hiroyuki; Morioka, Ichiro; Iijima, Kazumoto; Saito, Toshio; Saito, Kayoko; Takeuchi, Atsuko; Lai, Poh San; Bouike, Yoshihiro; Nishio, Hisahide; Shinohara, Masakazu

2017-12-18

Spinal muscular atrophy (SMA) is one of the most common autosomal recessive disorders. The symptoms are caused by defects of lower motor neurons in the spinal cord. More than 95% of SMA patients are homozygous for survival motor neuron 1 (SMN1) deletion. We previously developed a screening system for SMN1 deletion based on a modified competitive oligonucleotide priming-PCR (mCOP-PCR) technique using dried blood spot (DBS) on filter paper. This system is convenient for mass screening in the large population and/or first-tier diagnostic method of the patients in the remote areas. However, this system was still time-consuming and effort-taking, because it required pre-amplification procedure to avoid non-specific amplification and gel-electrophoresis to detect the presence or absence of SMN1 deletion. When the fresh blood samples are used instead of DBS, or when the gel-electrophoresis is replaced by real-time PCR, we may have a simpler and more rapid diagnostic method for SMA. To establish a simpler and more rapid diagnostic method of SMN1 deletion using fresh blood DNA. DNA samples extracted from fresh blood and stored at 4 ℃ for 1 month. The samples were assayed using a real-time mCOP-PCR system without pre-amplification procedures. DNA samples had already been genotyped by PCR-restriction fragment length polymorphism (PCR-RFLP), showing the presence or absence of SMN1 exon 7. The DNA samples were directly subjected to the mCOP-PCR step. The amplification of mCOP-PCR was monitored in a real-time PCR apparatus. The genotyping results of the real-time mCOP-PCR system using fresh blood DNA were completely matched with those of PCR-RFLP. In this real-time mCOP-PCR system using fresh blood-DNA, it took only four hours from extraction of DNA to detection of the presence or absence of SMN1 deletion, while it took more than 12 hours in PCR-RFLP. Our real-time mCOP-PCR system using fresh blood DNA was rapid and accurate, suggesting it may be useful for the first

UV durable colour pigment doped SmA liquid crystal composites for outdoor trans-reflective bi-stable displays

Science.gov (United States)

Xu, H.; Davey, A. B.; Crossland, W. A.; Chu, D. P.

2012-10-01

High brightness trans-reflective bi-stable displays based on smectic A (SmA) liquid crystals (LCs) can have nearly perfect transparency in the clear state and very high reflection in the scattered state. Because the LC material in use is stable under UV radiation, this kind of displays can stand for strong day-light and therefore be ideal for outdoor applications from e-books to public signage and advertisement. However, the colour application has been limited because the traditional colourants in use are conventional dyes which are lack of UV stability and that their colours are easily photo bleached. Here we present a colour SmA display demonstrator using pigments as colourant. Mixing pigments with SmA LCs and maintain the desirable optical switching performance is not straightforward. We show here how it can be done, including how to obtain fine sized pigment nano-particles, the effects of particle size and size distribution on the display performance. Our optimized pigments/SmA compositions can be driven by a low frequency waveform (~101Hz) to a scattered state to exhibit colour while by a high frequency waveform (~103Hz) to a cleared state showing no colour. Finally, we will present its excellent UV life-time (at least <7.2 years) in comparison with that of dye composition (~2.4 years). The complex interaction of pigment nano-particles with LC molecules and the resulting effects on the LC electro-optical performances are still to be fully understood. We hope this work will not only demonstrate a new and practical approach for outdoor reflective colour displays but also provide a new material system for fundamental liquid crystal colloid research work.

Magnetized Converging Flows toward the Hot Core in the Intermediate/High-mass Star-forming Region NGC 6334 V

International Nuclear Information System (INIS)

Juárez, Carmen; Girart, Josep M.; Zamora-Avilés, Manuel; Palau, Aina; Ballesteros-Paredes, Javier; Tang, Ya-Wen; Koch, Patrick M.; Liu, Hauyu Baobab; Zhang, Qizhou; Qiu, Keping

2017-01-01

We present Submillimeter Array (SMA) observations at 345 GHz toward the intermediate/high-mass cluster-forming region NGC 6334 V. From the dust emission we spatially resolve three dense condensations, the brightest one presenting the typical chemistry of a hot core. The magnetic field (derived from the dust polarized emission) shows a bimodal converging pattern toward the hot core. The molecular emission traces two filamentary structures at two different velocities, separated by 2 km s −1 , converging to the hot core and following the magnetic field distribution. We compare the velocity field and the magnetic field derived from the SMA observations with magnetohydrodynamic simulations of star-forming regions dominated by gravity. This comparison allows us to show how the gas falls in from the larger-scale extended dense core (∼0.1 pc) of NGC 6334 V toward the higher-density hot core region (∼0.02 pc) through two distinctive converging flows dragging the magnetic field, whose strength seems to have been overcome by gravity.

Sense of agency is related to gamma band coupling in an inferior parietal-preSMA circuitry

DEFF Research Database (Denmark)

Ritterband-Rosenbaum, Anina; Nielsen, Jens Bo; Christensen, Mark Schram

2014-01-01

with no SoA in the late task phase, but the test of the early task phase did not reveal any differences between presence and absence of SoA. We show that SoA is associated with a directionally specific between frequencies coupling from IPC to preSMA in the higher gamma (ɣ) band in the late task phase...

High-resolution SMA imaging of bright submillimetre sources from the SCUBA-2 Cosmology Legacy Survey

Science.gov (United States)

Hill, Ryley; Chapman, Scott C.; Scott, Douglas; Petitpas, Glen; Smail, Ian; Chapin, Edward L.; Gurwell, Mark A.; Perry, Ryan; Blain, Andrew W.; Bremer, Malcolm N.; Chen, Chian-Chou; Dunlop, James S.; Farrah, Duncan; Fazio, Giovanni G.; Geach, James E.; Howson, Paul; Ivison, R. J.; Lacaille, Kevin; Michałowski, Michał J.; Simpson, James M.; Swinbank, A. M.; van der Werf, Paul P.; Wilner, David J.

2018-06-01

We have used the Submillimeter Array (SMA) at 860 μm to observe the brightest sources in the Submillimeter Common User Bolometer Array-2 (SCUBA-2) Cosmology Legacy Survey (S2CLS). The goal of this survey is to exploit the large field of the S2CLS along with the resolution and sensitivity of the SMA to construct a large sample of these rare sources and to study their statistical properties. We have targeted 70 of the brightest single-dish SCUBA-2 850 μm sources down to S850 ≈ 8 mJy, achieving an average synthesized beam of 2.4 arcsec and an average rms of σ860 = 1.5 mJy beam-1 in our primary beam-corrected maps. We searched our SMA maps for 4σ peaks, corresponding to S860 ≳ 6 mJy sources, and detected 62, galaxies, including three pairs. We include in our study 35 archival observations, bringing our sample size to 105 bright single-dish submillimetre sources with interferometric follow-up. We compute the cumulative and differential number counts, finding them to overlap with previous single-dish survey number counts within the uncertainties, although our cumulative number count is systematically lower than the parent S2CLS cumulative number count by 14 ± 6 per cent between 11 and 15 mJy. We estimate the probability that a ≳10 mJy single-dish submillimetre source resolves into two or more galaxies with similar flux densities to be less than 15 per cent. Assuming the remaining 85 per cent of the targets are ultraluminous starburst galaxies between z = 2 and 3, we find a likely volume density of ≳400 M⊙ yr-1 sources to be {˜ } 3^{+0.7}_{-0.6} {× } 10^{-7} Mpc-3. We show that the descendants of these galaxies could be ≳4 × 1011 M⊙ local quiescent galaxies, and that about 10 per cent of their total stellar mass would have formed during these short bursts of star formation.

THE EFFECTIVENESS OF USING SCRABBLE AND BINGO GAME TECHNIQUE TOWARD STUDENTS’ VOCABULARY MASTERY AT THE TENTH GRADE OF SMA N 2 METRO ACADEMIC YEAR 2013/2014

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Ahmad Rosidi -

2017-02-01

Full Text Available Abstract: Vocabulary mastery is the activity to enrich the vocabulary, they master the vocabulary in order to be able to master four language skills. The problem formulation of this research are; (1  Is there any difference influence of using Scrabble and Bingo Game Technique toward Students’ Vocabulary Mastery at The Tenth Grade of SMA N 2 Metro Academic Year 2013/3014? (2 Which one is more effective between Scrabble and Bingo Game Technique toward Students’ Vocabulary Mastery at The Tenth Grade of SMA N 2 Metro Academic Year 2013/3014 ?, The object of this research are; (1 To know whether there is any difference Influence of using Scrabble and Bingo Game Technique toward Students’ Vocabulary Mastery at The Tenth Grade of SMA N 2 Metro Academic Year 2013/3014, (2 To know which one is more effective between Scrabble and Bingo Game Technique toward Students’ Vocabulary Mastery at The Tenth Grade of SMA N 2 Metro Academic Year 2013/3014. This research is Quantitative research. Research design that will be used in this research is true experimental design (pretest posttest control group design.. The population of this research is the students’ of SMA N 2 Metro Academic Year 2013/2014 that consist of 660 students. The sample is 60 students. As the sample, 30 as experimental class and 30 as  control class. In taking sample, the researcher used the cluster stratified random sampling. The data collecting tehniques the researcher used try-out, pre-test, treatment and post-test. The data analyzing tehniques, the researcher used normality test, homogenity test and hypothesis test. The differences of both the tehnique are Scrabble Game can make the students feel enjoy, creative and have a challenge and Bingo Game gives the students opportunity to identify the word interestingly. Based on the data analysis, the researcher uses t-test formula. The researcher got the result of tobserved = 3,69 and ttable is 2.00. it means that tobserved > ttable

PENGEMBANGAN BUDAYA SEKOLAH BERPRESTASI: STUDI TENTANG PENANAMAN NILAI DAN ETOS BERPRESTASI DI SMA KARANGTURI

Directory of Open Access Journals (Sweden)

Agus Yuliono

2013-04-01

Full Text Available Tujuan penelitian ini adalah untuk mendeskripsikan bentuk budaya sekolah berprestasi, proses penanaman nilai dan etos berprestasi kepada peserta didik dan mengetahui implikasi dari pengembangan budaya sekolah berprestasi di SMA Karangturi. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Pengumpulan data menggunakan teknik observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa bentuk budaya sekolah berprestasi di SMA Karangturi mencakup empat poin yaitu: keseimbangan antara pembinaan akademik dan nonakademik, penanaman karakter melalui pelajaran, budaya mencintai almamater dan pentingnya nilai kerokhanian. Penanaman nilai dan etos berprestasi pada peserta didik dilakukan melalui kegiatan orientasi sekolah, proses pembelajaran, evaluasi belajar, ekstrakurikuler, penghargaan prestasi, kecintaan terhadap almamater, keteladanan guru, kerjasama dengan orangtua peserta didik dan seragam patriot sebagai media penanaman budaya berprestasi. Implikasi penanaman pengembangan budaya sekolah berprestasi di SMA Karangturi terdapat dalam input (penerimaan siswa baru dan pencarian siswa berpotensi, proses (pengembangan program sekolah serta pengembangan kerjasama dan output (prestasi akademik dan nonakademik serta jumlah alumni yang melanjutkan ke perguruan tinggi. The objective of this study is to describe a model of school achievement culture, the cultivation of values ​​and ethos of achievement to students and know the implications of the development of school culture on students’ achievement in Karangturi high school. This study used a qualitative descriptive approach. Techniques of collecting data were observation, interviews and documentation. This study uses sources and methods triangulation for data validation. The results show that the  school achievement culture in Karangturi high school contains four pillars, namely: a balance between academic and non-academic achievement, building character

Styrene-maleic acid-copolymer conjugated zinc protoporphyrin as a candidate drug for tumor-targeted therapy and imaging.

Science.gov (United States)

Fang, Jun; Tsukigawa, Kenji; Liao, Long; Yin, Hongzhuan; Eguchi, Kanami; Maeda, Hiroshi

2016-01-01

Previous studies indicated the potential of zinc protoporphyrin (ZnPP) as an antitumor agent targeting to the tumor survival factor heme oxygenase-1, and/or for photodynamic therapy (PDT). In this study, to achieve tumor-targeted delivery, styrene-maleic acid-copolymer conjugated ZnPP (SMA-ZnPP) was synthesized via amide bond, which showed good water solubility, having ZnPP loading of 15%. More importantly, it forms micelles in aqueous solution with a mean particle size of 111.6 nm, whereas it has an apparent Mw of 65 kDa. This micelle formation was not detracted by serum albumin, suggesting it is stable in circulation. Further SMA-ZnPP conjugate will behave as an albumin complex in blood with much larger size (235 kDa) by virtue of the albumin binding property of SMA. Consequently, SMA-ZnPP conjugate exhibited prolonged circulating retention and preferential tumor accumulation by taking advantage of enhanced permeability and retention (EPR) effect. Clear tumor imaging was thus achieved by detecting the fluorescence of ZnPP. In addition, the cytotoxicity and PDT effect of SMA-ZnPP conjugate was confirmed in human cervical cancer HeLa cells. Light irradiation remarkably increased the cytotoxicity (IC50, from 33 to 5 μM). These findings may provide new options and knowledge for developing ZnPP based anticancer theranostic drugs.

PENGARUH LINGKUNGAN KERJA, KOMPENSASI KERJA, DAN MOTIVASI KERJA TERHADAP KINERJA GURU EKONOMI/ AKUNTANSI DI SMA NEGERI SE-KABUPATEN WONOSOBO

Directory of Open Access Journals (Sweden)

Siti Imroatun

2016-02-01

Full Text Available Kinerja guru sangat menentukan keberhasilan proses belajar yang efektif dan efisien. Dengan kinerja yang baik maka tujuan pendidikan dapat tercapai. Penelitian ini dilakukan di SMA Negeri se-Kabupaten wonosobo yang berjumlah sembilan sekolah yang dilatar belakangi bahwa kinerja guru di SMA Negeri se-Kabupaten Wonosobo belum optimal. Hal ini dilihat dari hasil observasi awal yang menunjukkan kurangnya persiapan sebelum mengajar, penggunaan metode pembelajaran yang kurang inovatif, dan pembelajaran berbasis teknologi kurang dapat dimanfaatkan secara optimal. Populasi dalam penelitian ini berjumlah 30 orang guru ekonomi yang tersebar di sembilan SMA Negeri se-Kabupaten Wonosobo. Sampel yang digunakan adalah semua guru ekonomi yang ada di SMA Negeri se-Kabupaten Wonosobo. Variabel yang diteliti dalam penelitian ini adalah lingkungan kerja, kompensasi kerja, dan motivasi kerja sebagai variabel bebas, serta kinerja guru sebagai variabel terikat. Metode pengumpulan data yang digunakan adalah angket atau kuesioner. Analisis data menggunakan analisis statistik deskriptif dan statistik inferensial.Hasil analisis deskriptif masing-masing variabel menunjukkan bahwa lingkungan kerja, kompensasi kerja, motivasi kerja dan kinerja guru termasuk kriteria baik. Lingkungan kerja berpengaruh positif terhadap kinerja guru sebesar 16,65%; kompensasi kerja berpengaruh positif terhadap kinerja guru sebesar 21,25%; dan motivasi kerja berpengaruh positif terhadap kinerja guru sebesar 31,92%.Penelitian ini terdapat pengaruh positif antara lingkungan kerja, kompensasi kerja dan motivasi kerja terhadap kinerja guru, baik secara simultan maupun parsial. Saran yang dapat diberikan adalah agar guru ekonomi terus meningkatkan kompetensi professional dengan menyesuaikan kemampuan peserta didik. Selain itu juga perlu ditingkatkan fasilitas yang mendukung kinerja guru, memberikan kompensasi sesuai dengan beban kerja guru dan selalu memberikan motivasi kepada guru ekonomi. Teacher

Dynamic expression of desmin, α-SMA and TGF-β1 during hepatic fibrogenesis induced by selective bile duct ligation in young rats

Energy Technology Data Exchange (ETDEWEB)

Gonçalves, J.O.; Tannuri, A.C.A.; Coelho, M.C.M.; Bendit, I.; Tannuri, U. [Laboratório de Pesquisa em Cirurgia Pediátrica (LIM-30), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil)

2014-08-15

We previously described a selective bile duct ligation model to elucidate the process of hepatic fibrogenesis in children with biliary atresia or intrahepatic biliary stenosis. Using this model, we identified changes in the expression of alpha smooth muscle actin (α-SMA) both in the obstructed parenchyma and in the hepatic parenchyma adjacent to the obstruction. However, the expression profiles of desmin and TGF-β1, molecules known to be involved in hepatic fibrogenesis, were unchanged when analyzed by semiquantitative polymerase chain reaction (RT-PCR). Thus, the molecular mechanisms involved in the modulation of liver fibrosis in this experimental model are not fully understood. This study aimed to evaluate the molecular changes in an experimental model of selective bile duct ligation and to compare the gene expression changes observed in RT-PCR and in real-time quantitative PCR (qRT‐PCR). Twenty-eight Wistar rats of both sexes and weaning age (21-23 days old) were used. The rats were separated into groups that were assessed 7 or 60 days after selective biliary duct ligation. The expression of desmin, α-SMA and TGF-β1 was examined in tissue from hepatic parenchyma with biliary obstruction (BO) and in hepatic parenchyma without biliary obstruction (WBO), using RT-PCR and qRT‐PCR. The results obtained in this study using these two methods were significantly different. The BO parenchyma had a more severe fibrogenic reaction, with increased α-SMA and TGF-β1 expression after 7 days. The WBO parenchyma presented a later, fibrotic response, with increased desmin expression 7 days after surgery and increased α-SMA 60 days after surgery. The qRT‐PCR technique was more sensitive to expression changes than the semiquantitative method.

Dynamic expression of desmin, α-SMA and TGF-β1 during hepatic fibrogenesis induced by selective bile duct ligation in young rats

International Nuclear Information System (INIS)

Gonçalves, J.O.; Tannuri, A.C.A.; Coelho, M.C.M.; Bendit, I.; Tannuri, U.

2014-01-01

We previously described a selective bile duct ligation model to elucidate the process of hepatic fibrogenesis in children with biliary atresia or intrahepatic biliary stenosis. Using this model, we identified changes in the expression of alpha smooth muscle actin (α-SMA) both in the obstructed parenchyma and in the hepatic parenchyma adjacent to the obstruction. However, the expression profiles of desmin and TGF-β1, molecules known to be involved in hepatic fibrogenesis, were unchanged when analyzed by semiquantitative polymerase chain reaction (RT-PCR). Thus, the molecular mechanisms involved in the modulation of liver fibrosis in this experimental model are not fully understood. This study aimed to evaluate the molecular changes in an experimental model of selective bile duct ligation and to compare the gene expression changes observed in RT-PCR and in real-time quantitative PCR (qRT‐PCR). Twenty-eight Wistar rats of both sexes and weaning age (21-23 days old) were used. The rats were separated into groups that were assessed 7 or 60 days after selective biliary duct ligation. The expression of desmin, α-SMA and TGF-β1 was examined in tissue from hepatic parenchyma with biliary obstruction (BO) and in hepatic parenchyma without biliary obstruction (WBO), using RT-PCR and qRT‐PCR. The results obtained in this study using these two methods were significantly different. The BO parenchyma had a more severe fibrogenic reaction, with increased α-SMA and TGF-β1 expression after 7 days. The WBO parenchyma presented a later, fibrotic response, with increased desmin expression 7 days after surgery and increased α-SMA 60 days after surgery. The qRT‐PCR technique was more sensitive to expression changes than the semiquantitative method

PERAN GURU PENJASORKES DALAM MENGATASI KENAKALAN SISWA (STUDI KASUS DI SMA NEGERI SE-KABUPATEN KENDAL TAHUN 2013

Directory of Open Access Journals (Sweden)

Irkham Kharisma

2015-06-01

Full Text Available The purpose of this study to determine, describe, and analyze the role of teachers in addressing student misbehavior penjasorkes Public High School students in Kendal. This study used qualitative methods, the location of the research conducted in SMA se-Kendal. Research subjects in this study were penjasorkes teacher, principal, BK teachers and students. Data collected by using observation, interviews and documentation. The validity of using triangulation source. Data analysis using descriptive analysis model according to Miles and Huberman. Based on the results of research conducted and has been linked with the theory Suparwoto, et al. It can be concluded that the role of teachers penjasorkes (1 in terms of preventive prevent student misbehavior is good. (2 is good in terms of repression. (3 in terms of curative and rehabilitation are good. The conclusions that can be drawn from this research is the teacher's role in addressing delinquency penjasorkes students in SMA se-Kendal has been running both in terms of preventive, repressive and curative or rehabilitation.

IGF-1 delivery to CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice.

Science.gov (United States)

Tsai, Li-Kai; Chen, Yi-Chun; Cheng, Wei-Cheng; Ting, Chen-Hung; Dodge, James C; Hwu, Wuh-Liang; Cheng, Seng H; Passini, Marco A

2012-01-01

The efficacy of administering a recombinant adeno-associated virus (AAV) vector encoding human IGF-1 (AAV2/1-hIGF-1) into the deep cerebellar nucleus (DCN) of a type III SMA mouse model was evaluated. High levels of IGF-1 transcripts and protein were detected in the spinal cord at 2 months post-injection demonstrating that axonal connections between the cerebellum and spinal cord were able to act as conduits for the viral vector and protein to the spinal cord. Mice treated with AAV2/1-hIGF-1 and analyzed 8 months later showed changes in endogenous Bax and Bcl-xl levels in spinal cord motor neurons that were consistent with IGF-1-mediated anti-apoptotic effects on motor neurons. However, although AAV2/1-hIGF-1 treatment reduced the extent of motor neuron cell death, the majority of rescued motor neurons were non-functional, as they lacked axons that innervated the muscles. Furthermore, treated SMA mice exhibited abnormal muscle fibers, aberrant neuromuscular junction structure, and impaired performance on motor function tests. These data indicate that although CNS-directed expression of IGF-1 could reduce motor neuron cell death, this did not translate to improvements in motor function in an adult mouse model of type III SMA. Copyright © 2011 Elsevier Inc. All rights reserved.

Analisis Dampak Negatif Facebook pada Remaja Kelas X IPS SMA Kemala Bhayangkari Kubu Raya

OpenAIRE

Malindo, Hari

2017-01-01

The negative impact of the use of facebook is a result caused the use of facebook excessively that can give rise to abuse and diversion to brpengaruh directly to the consumer, and often waste time just to tamper with his facebook account, if not used wisely facebook will have a negative impact to pengggunanya it sendiri..Oleh because the researchers wanted to know more profound analysis of the negative impact on teenagers facebook IPS class X SMA Kemala Bhayangkari Kubu Raya.A common problem ...

Hubungan Merokok Dengan Kejadian Insomnia Pada Remaja Di SMA Negeri 1 Remboken Kabupaten Minahasa

OpenAIRE

Kairupan, Juwinda Meini Ayu; Rottie, Julia; Malara, Reginus

2016-01-01

: Insomnia is difficulty initiating and maintaining sleep so can not meet the need for adequate sleep , both quantity and quality. Smoking is one of the causes of insomnia. Smoking is an act of burning a tabacco which inhaled the smoke from the burning process in a form of cigarette or a pipe. The purpose of this study was to analyze the relationship of smoking with the incidence of insomnia in adolescents at SMA N 1 Remboken Minahasa District. The research method is used observational analy...

Penerapan Pembelajaran Model Kooperatif Tipe Think-Pair-Share Dalam Materi Usaha Dan Energi Ditinjau Dari Gender Siswa Kelas Xi Ipa Sma Negeri 1 Sungai Ambawang

Directory of Open Access Journals (Sweden)

Ira Nofita Sari

2016-09-01

Full Text Available Penelitian ini bertujuan untuk mengetahui penerapan pembelajaran model kooperatif tipe think-pair-share dalam materi usaha dan energi ditinjau dari gender siswa kelas XI IPA SMA Negeri 1 Sungai Ambawang. Adapun variabel dalam penelitian ini adalah hasil belajar siswa laki-laki dan hasil belajar siswa perempuan. Metode yang digunakan dalam peneltian ini adalah metode eksperimen dan bentuk penelitian eksperimen yang digunakan adalah Pre-Eksperimental Designs dengan rancangan penelitian The One-Shot Case Study.Sampel yang digunakan ialah kelas XI IPA 1 yang diambil secara purposive sampling.. Teknik pengumpul data yang digunakan dalam penelitian ini adalah teknik pengukuran dengan alat pengumpul data berupa tes yang berbentuk essay. Berdasarkan hasil analisis data penelitian diperoleh kesimpulan: (1 Rata-rata hasil belajar siswa laki-laki yang diajarkan model pembelajaran kooperatif tipe think-pair-share dalam materi usaha dan energi siswa kelas XI IPA SMA Negeri 1 Sungai Ambawang mencapai KKM (72 dengan nilai signifikansi lebih besar dari taraf signifikansi 5% (0,715 > 0,05. (2 Rata-rata hasil belajar siswa perempuan yang diajarkan model pembelajaran kooperatif tipe think-pair-share dalam materi usaha dan energi siswa kelas XI IPA SMA Negeri 1 Sungai Ambawang mencapai KKM (72 dengan nilai signifikansi lebih besar dari taraf signifikansi 5% (0,185 > 0,05. (3 Terdapat perbedaan antara rata-rata hasil belajar siswa laki-laki dengan rata-rata hasil belajar siswa perempuan yang diajarkan model pembelajaran kooperatif tipe Think-Pair-Share dalam materi usaha dan energi siswa kelas XI IPA SMA Negeri 1 Sungai Ambawang dengan nilai signifikansi lebih besar dari taraf signifikansi 5% (0,101 > 0,05.

Many-Objective Distinct Candidates Optimization using Differential Evolution

DEFF Research Database (Denmark)

Justesen, Peter; Ursem, Rasmus Kjær

2010-01-01

for each objective. The Many-Objective Distinct Candidates Optimization using Differential Evolution (MODCODE) algorithm takes a novel approach by focusing search using a user-defined number of subpopulations each returning a distinct optimal solution within the preferred region of interest. In this paper......, we present the novel MODCODE algorithm incorporating the ROD measure to measure and control candidate distinctiveness. MODCODE is tested against GDE3 on three real world centrifugal pump design problems supplied by Grundfos. Our algorithm outperforms GDE3 on all problems with respect to all...

Physical mapping of a commonly deleted region, the site of a candidate tumor suppressor gene, at 12q22 in human male germ cell tumors

Energy Technology Data Exchange (ETDEWEB)

Murty, V.V.V.S.; Bosl, G.J.; Chaganti, R.S.K. [Memorial Sloan-Kettering Cancer Center, New York, NY (United States)] [and others

1996-08-01

A candidate tumor suppressor gene (TSG) site at 12q22 characterized by a high frequency of loss of heterozygosity (LOH) and a homozygous deletion has previously (LOH) and a homozygous deletion has previously been reported in human male germ cell tumors (GCTs). In a detailed deletion mapping analysis of 67 normal-tumor DNAs utilizing 20 polymorphic markers mapped to 12q22-q24, we identified the limits of the minimal region of deletion at 12q22 between D12S377 (priximal) and D12S296 (distal). We have constructed a YAC contig map of a 3-cM region of this band between the proximal marker D12S101 and the distal marker D12S346, which contained the minimal region of deletion in GCTs. The map is composed of 53 overlapping YACs and 3 cosmids onto which 25 polymorphic and nonpolymorphic sequence-tagged sites (STSs) were placed in a unique order. The size of the minimal region of deletion was approximately 2 Mb from overlapping, nonchimeric YACs that spanned the region. We also developed a radiation hybrid (RH) map of the region between D12S101 and D12S346 containing 17 loci. The consensus order developed by RH mapping is in good agreement with the YAC STS-content map order. The RH map estimated the distance between D12S101 and D12S346 to be 246 cR{sub 8000} and the minimal region of deletion to be 141 cR{sub 8000}. In addition, four genes that were previously mapped to 12q22 have been excluded as candidate genes. The leads gained from the deletion mapping and physical maps should expedite the isolation and characterization of the TSG at 12q22. 35 refs., 4 figs., 2 tabs.

Magnetized Converging Flows toward the Hot Core in the Intermediate/High-mass Star-forming Region NGC 6334 V

Energy Technology Data Exchange (ETDEWEB)

Juárez, Carmen; Girart, Josep M. [Institut de Ciències de l’Espai, (CSIC-IEEC), Campus UAB, Carrer de Can Magrans, S/N, E-08193 Cerdanyola del Vallès, Catalonia (Spain); Zamora-Avilés, Manuel; Palau, Aina; Ballesteros-Paredes, Javier [Instituto de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, P.O. Box 3-72, 58090, Morelia, Michoacán (Mexico); Tang, Ya-Wen; Koch, Patrick M.; Liu, Hauyu Baobab [Academia Sinica Institute of Astronomy and Astrophysics, P.O. Box 23-141, Taipei, 10617, Taiwan (China); Zhang, Qizhou [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Qiu, Keping, E-mail: juarez@ice.cat [School of Astronomy and Space Science, Nanjing University, 163 Xianlin Avenue, Nanjing 210023 (China)

2017-07-20

We present Submillimeter Array (SMA) observations at 345 GHz toward the intermediate/high-mass cluster-forming region NGC 6334 V. From the dust emission we spatially resolve three dense condensations, the brightest one presenting the typical chemistry of a hot core. The magnetic field (derived from the dust polarized emission) shows a bimodal converging pattern toward the hot core. The molecular emission traces two filamentary structures at two different velocities, separated by 2 km s{sup −1}, converging to the hot core and following the magnetic field distribution. We compare the velocity field and the magnetic field derived from the SMA observations with magnetohydrodynamic simulations of star-forming regions dominated by gravity. This comparison allows us to show how the gas falls in from the larger-scale extended dense core (∼0.1 pc) of NGC 6334 V toward the higher-density hot core region (∼0.02 pc) through two distinctive converging flows dragging the magnetic field, whose strength seems to have been overcome by gravity.

Genetic basis of qualitative and quantitative resistance to powdery mildew in wheat: from consensus regions to candidate genes.

Science.gov (United States)

Marone, Daniela; Russo, Maria A; Laidò, Giovanni; De Vita, Pasquale; Papa, Roberto; Blanco, Antonio; Gadaleta, Agata; Rubiales, Diego; Mastrangelo, Anna M

2013-08-19

Powdery mildew (Blumeria graminis f. sp. tritici) is one of the most damaging diseases of wheat. The objective of this study was to identify the wheat genomic regions that are involved in the control of powdery mildew resistance through a quantitative trait loci (QTL) meta-analysis approach. This meta-analysis allows the use of collected QTL data from different published studies to obtain consensus QTL across different genetic backgrounds, thus providing a better definition of the regions responsible for the trait, and the possibility to obtain molecular markers that will be suitable for marker-assisted selection. Five QTL for resistance to powdery mildew were identified under field conditions in the durum-wheat segregating population Creso × Pedroso. An integrated map was developed for the projection of resistance genes/ alleles and the QTL from the present study and the literature, and to investigate their distribution in the wheat genome. Molecular markers that correspond to candidate genes for plant responses to pathogens were also projected onto the map, particularly considering NBS-LRR and receptor-like protein kinases. More than 80 independent QTL and 51 resistance genes from 62 different mapping populations were projected onto the consensus map using the Biomercator statistical software. Twenty-four MQTL that comprised 2-6 initial QTL that had widely varying confidence intervals were found on 15 chromosomes. The co-location of the resistance QTL and genes was investigated. Moreover, from analysis of the sequences of DArT markers, 28 DArT clones mapped on wheat chromosomes have been shown to be associated with the NBS-LRR genes and positioned in the same regions as the MQTL for powdery mildew resistance. The results from the present study provide a detailed analysis of the genetic basis of resistance to powdery mildew in wheat. The study of the Creso × Pedroso durum-wheat population has revealed some QTL that had not been previously identified. Furthermore

Hubungan Bermain Video Game Terhadap Kejadian Insomnia Pada Kalangan Remaja Di Sma Negeri 12 Medan

OpenAIRE

Pangaribuan, Hotman Parasian

2015-01-01

The number of adolescent who played video game was increased now days. This can cause many problems in social relationship, behavioral, and their sleep pattern like insomnia. This cross sectional study aimed to evaluate the relationship between playing video game with insomnia among the adolescent. Our total sample was 100 students in SMA Negeri 12 Medan. The sample was chosen by consequtive sampling. The data was taken by interview using questionnaire. From our result, the major...

Pembanguna Sistem Informasi Manajemen Keluhan Siswa Berbasi Web pada SMA PGRI 6 Malang Menggunakan Metode Waterfall

OpenAIRE

Wiwin Kuswinardi, Marissa Renny Leon/

2014-01-01

Leon, Marissa Renny. 2014. Development of web based Management Information System of Student Complaints In SMA PGRI 6 Malang Using Waterfall Method. 109Thesis, information systems Study Program, Faculty of Information Technology, kanjuruhan Universitas of Malang. Supervisor: Wiwin Kuswinardi,Kom., M.KomDelivering complaint of students is still less effective Students write complaints on paper, but there are some constraints faced by the homeroom teacher, if the paper of ...

Pre-SMA gray-matter density predicts individual differences in action selection in the face of conscious and unconscious response conflict

NARCIS (Netherlands)

van Gaal, S.; Scholte, H.S.; Lamme, V.A.F.; Fahrenfort, J.J.; Ridderinkhof, K.R.

2011-01-01

The presupplementary motor area (pre-SMA) is considered key in contributing to voluntary action selection during response conflict. Here we test whether individual differences in the ability to select appropriate actions in the face of strong (conscious) and weak (virtually unconscious) distracting

Integrative taxonomy supports new candidate fish species in a poorly studied neotropical region: the Jequitinhonha River Basin.

Science.gov (United States)

Pugedo, Marina Lages; de Andrade Neto, Francisco Ricardo; Pessali, Tiago Casarim; Birindelli, José Luís Olivan; Carvalho, Daniel Cardoso

2016-06-01

Molecular identification through DNA barcoding has been proposed as a way to standardize a global biodiversity identification system using a partial sequence of the mitochondrial COI gene. We applied an integrative approach using DNA barcoding and traditional morphology-based bioassessment to identify fish from a neotropical region possessing low taxonomic knowledge: the Jequitinhonha River Basin (Southeastern Brazil). The Jequitinhonha River Basin (JRB) has a high rate of endemism and is considered an area of high priority for fish conservation, with estimates indicating the presence of around 110 native and non-indigenous species. DNA barcodes were obtained from 260 individuals belonging to 52 species distributed among 35 genera, 21 families and 6 orders, including threatened and rare species such as Rhamdia jequitinhonha and Steindachneridion amblyurum. The mean Kimura two-parameter genetic distances within species, genera and families were: 0.44, 12.16 and 20.58 %, respectively. Mean intraspecific genetic variation ranged from 0 to 11.43 %, and high values (>2 %) were recovered for five species. Species with a deep intraspecific distance, possibly flagging overlooked taxa, were detected within the genus Pimelodella. Fifteen species, only identified to the genus level, had unique BINs, with a nearest neighbor distance over 2 % and therefore, potential new candidate species supported by DNA barcoding. The integrative taxonomy approach using DNA barcoding and traditional taxonomy may be a remedy to taxonomy impediment, accelerating species identification by flagging potential new candidate species and to adequately conserve the megadiverse neotropical ichthyofauna.

PENGARUH PROJECT BASED LEARNING TERHADAP KETERAMPILAN PROSES SAINS SISWA KELAS X SMA NEGERI SIDOARJO

Directory of Open Access Journals (Sweden)

Nuril Maghfiroh

2016-08-01

Tujuan penelitian ini adalah untuk mengetahui pengaruh pembelajaran Project Based Learning terhadap keterampilan proses sains siswa kelas X SMA Negeri 4 Sidoarjo. Penelitian ini menggunakan metode Quasi Eksperimen dengan rancangan pretest postest non-equivalent control group design. Penentuan sampel mempertimbangkan kemampuan kognitif yang setara antara dua kelas yang menjadi kelompok kontrol dan kelompok eksperimen. Keterampilan proses sains diukur melalui tes tulis yang kemudian dianalisis dengan rubrik penilaian yang sudah disesuaikan untuk setiap aspek keterampilan proses sains. Hasil penelitian menunjukkan bahwa ada pengaruh pembelajaran Project Based Learning terhadap keterampilan proses sains siswa.

Soft and smart modular structures actuated by shape memory alloy (SMA) wires as tentacles of soft robots

Science.gov (United States)

Jin, Hu; Dong, Erbao; Xu, Min; Liu, Chunshan; Alici, Gursel; Jie, Yang

2016-08-01

This paper introduces the design and fabrication of a multi-layered smart modular structure (SMS) that has been inspired by the muscular organs and modularity in soft animals. The SMS is capable of planar reciprocal motion of bending in heating process and recovering in cooling process when SMA wires carry out phase transformation. An adaptive regulation heating strategy is applied to avoid overheating and achieve bending range control of the SMS based on the resistance feedback of the SMA wires which as actuator of the SMS. The SMS can modular assemble soft robots with multiple morphologies such as lateral robots, bilateral robots and actinomorphic robots. A five-armed actinomorphic soft robot is conducted to crawling in terrestrial ground (max speed: 140 mm s-1, 0.7 body s-1), swimming in underwater environment (max speed: 67 mm s-1, 2.5 height s-1) and griping fragile objects (max object weight: 0.91 kg, 15 times the weight of itself). Those demonstrate that the performance of the SMS is good enough to be modular units to establish soft robots which possess a high speed of response, good adaptability and a safe interaction with their environments.

Pendekatan Pengajaran Reciprocal Teaching Berpotensi Meningkatkan Ketuntasan Hasil Belajar Biologi Siswa SMA

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Nur Efendi

2013-02-01

Full Text Available Mutu pembelajaran Biologi masih rendah. Rendahnya mutu pembelajaran ini disebabkan oleh faktor pembelajaran yang masih berpusat pada guru (teacher centered tanpa melibatkan siswa untuk berpatisipasi pada proses untuk mendapatkan informasi dari kegiatan pembelajaran tersebut. Pengajaran Resiprok (Reciprocal Teaching merupakan salah satu strategi pendekatan pembelajaran yang dapat diterapkan untuk meningkatkan ketuntasan belajar siswa pada mata pelajaran biologi SMA, sehingga mutu pembelajaran mengalami ketercapaian ketuntasan hasil belajar yang ditetapkan. Tahapan Pengajajaran Resiprok adalah: (1 membaca  dan mencari ide pokok bacaan berdasarkan teks bacaan yang disediakan, (2 membuat pertanyaan, (3 menjawab pertanyaan, (4 merangkum informasi yang penting, (5 memprediksi, (6 mengidentifikasi hal-hal yang tidak jelas dari teks bacaan, (7 mengklarifikasi hal-hal yang tidak jelas tersebut.

Hubungan Penggunaan Media Sosial Dengan Kemampuan Interaksi Sosial Remaja di SMA Negeri 1 Kota Medan

OpenAIRE

Nugraheni, Auliya Tunnisaa

2016-01-01

Social media today is considered as an important daily need. The intensity of using it by adolescents is influenced by their need for information, either academic or non-academic information. The inclination of using it as a communication facility can directly effects one of the social interactions aspect among individual. The objective of this research was to find out the correlation of using social media with the capacity of social interaction in adolescents at SMA Negeri 1, Medan, using co...

PENGEMBANGAN MODEL COMPUTER-BASED E-LEARNING UNTUK MENINGKATKAN KEMAMPUAN HIGH ORDER MATHEMATICAL THINKING SISWA SMA

OpenAIRE

Jarnawi Afgani Dahlan; Yaya Sukjaya Kusumah; Mr Heri Sutarno

2011-01-01

The focus of this research is on the development of mathematics teaching and learning activity which is based on the application of computer software. The aim of research is as follows : 1) to identify some mathematics topics which feasible to be presented by computer-based e-learning, 2) design, develop, and implement computer-based e-learning on mathematics, and 3) analyze the impact of computer-based e-learning in the enhancement of SMA students’ high order mathematical thinking. All activ...

Planet Candidate Validation in K2 Crowded Fields

Science.gov (United States)

Rampalli, Rayna; Vanderburg, Andrew; Latham, David; Quinn, Samuel

2018-01-01

In just three years, the K2 mission has yielded some remarkable outcomes with the discovery of over 100 confirmed planets and 500 reported planet candidates to be validated. One challenge with this mission is the search for planets located in star-crowded regions. Campaign 13 is one such example, located towards the galactic plane in the constellation of Taurus. We subject the potential planetary candidates to a validation process involving spectroscopy to derive certain stellar parameters. Seeing-limited on/off imaging follow-up is also utilized in order to rule out false positives due to nearby eclipsing binaries. Using Markov chain Monte Carlo analysis, the best-fit parameters for each candidate are generated. These will be suitable for finding a candidate’s false positive probability through methods including feeding such parameters into the Validation of Exoplanet Signals using a Probabilistic Algorithm (VESPA). These techniques and results serve as important tools for conducting candidate validation and follow-up observations for space-based missions such as the upcoming TESS mission since TESS’s large camera pixels resemble K2’s star-crowded fields.

[Eng] Voting for Parties or for Candidates? The Trade-Off Between Party and Personal Representation in Spanish Regional and Local Elections

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Pablo Barberá

2010-01-01

Full Text Available When voters cast their ballot, are they choosing a candidate or a party? Electoral systems have a significant impact on how this question is answered in each country. As previous literature has shown, some electoral rules foster a more personal representation, while others strengthen the intermediary role of parties. In this paper I maintain that there exists a trade-off between these two types of representation. To empirically verify its existence and how it works, I have chosen local and regional elections in Spain as a case study. Given that they take place simultaneously under similar electoral systems, they can be considered a natural experiment for the study of this trade-off, which allows me to overcome the potential problems of endogeneity present in previous studies. By measuring the significance of ideological closeness and candidate evaluations in voters? decisions at each level, it is shown that the importance of personal representation increases in local elections at the expense of a less frequent use of ideological proximity as an informational shortcut, thus confirming the existence of the trade-off.

May functional imaging be helpful for behavioral assessment in children? Regions of motor and associative cortico-subcortical circuits can be differentiated by laterality and rostrality

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Julia M. August

2015-06-01

Full Text Available Background: Cortico-subcortical circuits are organized into the sensorimotor, associative and limbic loop. These neuronal preconditions play an important role regarding the understanding and treatment of behavioral problems in children. Differencing evidence argues for a lateralized organization of the sensorimotor loop and a bilateral (i.e. non-lateralized organization of the associative loop. However, a firm behavioral-neurobiological distinction of these circuits has been difficult, specifically in children. Objectives: Thus, the aim was a comprehensive functional visualization and differentiation of the sensorimotor and the associative circuit during childhood. As a new approach, laterality and rostrality features were used to distinguish between the two circuits within one single motor task. Methods: 24 healthy boys performed self-paced index finger tapping with each hand separately during functional magnetic resonance imaging at 3 Tesla. Results: A contrast analysis for left against right hand movement revealed lateralized activation in typical sensorimotor regions such as primary sensorimotor cortex, caudal supplementary motor area (SMA, caudal putamen and thalamus. A conjunction analysis confirmed bilateral involvement of known associative regions including pre-SMA, rostral SMA and rostral putamen. Conclusion: A functional visualization of two distinct corticostriatal circuits is provided in childhood. Both, the sensorimotor and associative circuit may be discriminated by their laterality characteristics already in minors. Additionally, the results support the concept of a modified functional subdivision of the SMA in a rostral (associative and caudal (motor part. A further development of this approach might help to nurture behavioral assessment and neurofeedback training in child mental health.

ANALISIS KELAYAKAN ISI BUKU TEKS MATA PELAJARAN EKONOMI SMA KELAS X BERDASARKAN KURIKULUM TINGKAT SATAUAN PENDIDIKAN ( KTSP DI KABUPATEN SEMARANG

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Koeri Ulinuha

2016-02-01

Full Text Available Tujuan penelitian ini adalah untuk mengetahui apakah buku teks ekonomi SMA kelas X yang digunakan di Kabupaten Semarang sudah memenuhi standar kelayakan isi buku teks ekonomi menurut BSNP. Dan manfaat penelitian ini dapat memilih dan mempertimbankan dalam memilih buku teks pelajaran untuk refrensi belajar baik pihak siswa, guru dan pihak sekolahPenelitian ini dilakuakan terhadap isi buku teks pelajaran yang dianalisis secara kualitatif. Sehingga penelitian ini disebut penelitian deskriptif kualitatif. Teknik penelitian yang di gunakan adalah adalah teknik triangulasi. Analisis buku teks ekonomi untuk SMA kelas X melibatkan 5 orang penilai, yaitu 5 guru ekonomi. Dari 5 SMAN yang mengunakan buku teks pelajaran ekonomi dengan pengarang Alam S. dan penerbit Esis. Teknik pengumpulan data dengan lembar penilaian buku teks ekonomi dari BSNP dan menggunakan teknik wawancara terhadap dua guru ekonomi untuk memperkuat hasil dari penilaian dari buku teks ekonomi kelas X.Data yang diperoleh dalam penelitian ini berupa hasil penilaian yang berupa skor penilian dan hasil wawancara. Berdasarkan hasil analisis dapat disimpulkan bahwa buku ekonomi SMA Kelas X karangan Alam S. yang digunakan di Kabupaten Semarang sudah memenuhi standar kelayakan isi menurut BSNP. Buku teks ekonomi untuk SMA Kelas X karangan Alam S. dapat digunakan sebagai sumber belajar dalam pembelajaran ekonomi di SMA kelas X. Selain itu, perlu diadakan penelitian lebih lanjut untuk menganalisis buku teks ekonomi lain yang digunakan di Kabupaten Semarang.. The purpose of this research was to know whether textbooks high school economics class X used in Semarang Regancy already meet the standards of eligibility of the contents of the textbook economics according to BSNP. Analysis of economic text books for high school classes X involves 5 persons appraisers, i.e. 5 economics teacher. From 5 SMAN using textbook economics lessons with author and Publisher Alam S. Esis.. Data collection techniques

Kondisi Stres Akademik Siswa SMA Negeri di Kota Padang

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Taufik Taufik

2014-01-01

Full Text Available This research conduct base from increasing the National Examination standards from recent years, and overload student’s learning activity in Senior High School (SMA. These conditions as triggers stress students, from a long time, its influence on their learning. Based that, the research is to identify level of student academic stress, and differences base gender, and school location. This research use Cluster Random Sampling. Samples are grouped into 3 (three, that’s school is located in downtown, midtown and the Suburbs. Research findings show that there are 15% of student’s stress academic at low levels of, 71,8% experiencing stress academic at medium level, and 13.2% of students experiencing stress academic at high level. There was no significant difference between the academic stress Student SMAN in Padang by location and gender. These research findings can then be an important basic need for guidance and counseling services in order to decrease the level of stress of academic students in Padang city, so that they can learn by making every effort that is optimal.

Shape memory alloy wires turn composites into smart structures: I. Material requirements

Science.gov (United States)

Schrooten, Jan; Michaud, Veronique J.; Zheng, Yanjun; Balta-Neumann, J. Antonio; Manson, Jan-Anders E.

2002-07-01

Composites containing thin Shape Memory Alloy (SMA) wires show great potential as materials able to adapt their shape, thermal behavior or vibrational properties to external stimuli. The functional properties of SMA-composites are directly related to the constraining effect of the matrix on the reversible martensitic transformation of the embedded pre-strained SMA wires. The present work reports results of a concerted European effort towards a fundamental understanding of the manufacturing and design of SMA composites. This first part investigates the transformational behavior of constrained SMA wires and its translation into functional properties of SMA composites. Thermodynamic and thermomechanical experiments were performed on SMA wires. A model was developed to simulate the thermomechanical behavior of the wires. From the screening of potential wires it was concluded that NiTiCu, as well as R-phase NiTi appeared as best candidates. Requirements for the host composite materials were surveyed. A Kevlar-epoxy system was chosen. Finally, the quality of the SMA wire-resin interface was assessed by two different techniques. These indicated that a thin oxide layer seems to provide the best interfacial strength. A temperature window in which SMA composites can be safely used was also defined. The manufacturing and properties of the SMA composites will be discussed in Part II.

HUBUNGAN KETERPAPARAN MEDIA MASSA, PERAN TEMAN SEBAYA TERHADAP TINDAKAN SEKSUAL DI SMA AN-NAAS

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rika istawati

2017-06-01

Full Text Available Masa remaja merupakan masa peralihan antara tahap anak dan dewasa dimana pada masa ini mereka sangat rentan terpapar informasi dari media massa dan teman sebaya terutama seks bebas. Data SKRRI mempunyai teman yang pernah berhubungan seksual pada usia 14-19 tahun dengan persentasi perempuan 37,7% dan laki-laki 30,9% dan Kementerian Komunikasi dan Informasi menyebut 62,1% siswa mengaku penah melakukan hubungan seks. Observasi yang di lakukan oleh peneliti di SMA AN-NAAS Pekanbaru diketahui adanya 2 siswa  yang tertangkap menyimpan dan menonton video porno di handphone dan melalui wawancara peneliti dengan 8 siswi mereka mengatakan adanya 1 siswi yang hamil diluar nikah dan 2 siswi diantaranya mengaku sering datang ketempat yang berisiko terhadap tindakan seksual. Tujuan Penelitian ini untuk mengetahui hubungan keterpaparan media massa dan peran teman sebaya terhadap tindakan seksual. Desain penelitian yang digunakan adalah cross sectional, populasi penelitian adalah seluruh siswa kelas SMA AN-NAAS Pekanbaru yaitu 123 responden. Sampel penelitian 94 orang dengan teknik stratified random sampling. Alat ukur yang digunakan adalah angket, data diolah menggunakan komputer. Analisa data secara univariat dan bivariat dengan uji chi square dengan ketentuan α (0,5. Hasil penelitian didapatkan uji statistik menunjukkan adanya hubungan keterpaparan media massa dengan tindakan seksual dimana nilai p value 0,000 < 0,05, terdapat hubungan yang bermakna antara peran teman sebaya dengan tindakan seksual, dimana p value  0,001 < 0,05. Bagi pihak sekolah diharapkan untuk meningkatkan kegiatan di sekolah seperti ekstrakurikuler dan guru membimbing serta memberi pengawasan yang ketat terhadap siswanya.   

Genome scans on experimentally evolved populations reveal candidate regions for adaptation to plant resistance in the potato cyst nematode Globodera pallida.

Science.gov (United States)

Eoche-Bosy, D; Gautier, M; Esquibet, M; Legeai, F; Bretaudeau, A; Bouchez, O; Fournet, S; Grenier, E; Montarry, J

2017-09-01

Improving resistance durability involves to be able to predict the adaptation speed of pathogen populations. Identifying the genetic bases of pathogen adaptation to plant resistances is a useful step to better understand and anticipate this phenomenon. Globodera pallida is a major pest of potato crop for which a resistance QTL, GpaV vrn , has been identified in Solanum vernei. However, its durability is threatened as G. pallida populations are able to adapt to the resistance in few generations. The aim of this study was to investigate the genomic regions involved in the resistance breakdown by coupling experimental evolution and high-density genome scan. We performed a whole-genome resequencing of pools of individuals (Pool-Seq) belonging to G. pallida lineages derived from two independent populations having experimentally evolved on susceptible and resistant potato cultivars. About 1.6 million SNPs were used to perform the genome scan using a recent model testing for adaptive differentiation and association to population-specific covariables. We identified 275 outliers and 31 of them, which also showed a significant reduction in diversity in adapted lineages, were investigated for their genic environment. Some candidate genomic regions contained genes putatively encoding effectors and were enriched in SPRYSECs, known in cyst nematodes to be involved in pathogenicity and in (a)virulence. Validated candidate SNPs will provide a useful molecular tool to follow frequencies of virulence alleles in natural G. pallida populations and define efficient strategies of use of potato resistances maximizing their durability. © 2017 John Wiley & Sons Ltd.

Association of candidate genes with drought tolerance traits in diverse perennial ryegrass accessions

Science.gov (United States)

Xiaoqing Yu; Guihua Bai; Shuwei Liu; Na Luo; Ying Wang; Douglas S. Richmond; Paula M. Pijut; Scott A. Jackson; Jianming Yu; Yiwei. Jiang

2013-01-01

Drought is a major environmental stress limiting growth of perennial grasses in temperate regions. Plant drought tolerance is a complex trait that is controlled by multiple genes. Candidate gene association mapping provides a powerful tool for dissection of complex traits. Candidate gene association mapping of drought tolerance traits was conducted in 192 diverse...

Evaluation of permanent deformation of CRM-reinforced SMA and its correlation with dynamic stiffness and dynamic creep.

Science.gov (United States)

Mashaan, Nuha Salim; Karim, Mohamed Rehan

2013-01-01

Today, rapid economic and industrial growth generates increasing amounts of waste materials such as waste tyre rubber. Attempts to inspire a green technology which is more environmentally friendly that can produce economic value are a major consideration in the utilization of waste materials. The aim of this study is to evaluate the effect of waste tyre rubber (crumb rubber modifier (CRM)), in stone mastic asphalt (SMA 20) performance. The virgin bitumen (80/100) penetration grade was used, modified with crumb rubber at four different modification levels, namely, 6%, 12%, 16%, and 20% by weight of the bitumen. The testing undertaken on the asphalt mix comprises the indirect tensile (dynamic stiffness), dynamic creep, and wheel tracking tests. By the experimentation, the appropriate amount of CRM was found to be 16% by weight of bitumen. The results show that the addition of CRM into the mixture has an obvious significant effect on the performance properties of SMA which could improve the mixture's resistance against permanent deformation. Further, higher correlation coefficient was obtained between the rut depth and permanent strain as compared to resilient modulus; thus dynamic creep test might be a more reliable test in evaluating the rut resistance of asphalt mixture.

Evaluation of Permanent Deformation of CRM-Reinforced SMA and Its Correlation with Dynamic Stiffness and Dynamic Creep

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Nuha Salim Mashaan

2013-01-01

Full Text Available Today, rapid economic and industrial growth generates increasing amounts of waste materials such as waste tyre rubber. Attempts to inspire a green technology which is more environmentally friendly that can produce economic value are a major consideration in the utilization of waste materials. The aim of this study is to evaluate the effect of waste tyre rubber (crumb rubber modifier (CRM, in stone mastic asphalt (SMA 20 performance. The virgin bitumen (80/100 penetration grade was used, modified with crumb rubber at four different modification levels, namely, 6%, 12%, 16%, and 20% by weight of the bitumen. The testing undertaken on the asphalt mix comprises the indirect tensile (dynamic stiffness, dynamic creep, and wheel tracking tests. By the experimentation, the appropriate amount of CRM was found to be 16% by weight of bitumen. The results show that the addition of CRM into the mixture has an obvious significant effect on the performance properties of SMA which could improve the mixture's resistance against permanent deformation. Further, higher correlation coefficient was obtained between the rut depth and permanent strain as compared to resilient modulus; thus dynamic creep test might be a more reliable test in evaluating the rut resistance of asphalt mixture.

Selection in the dopamine receptor 2 gene: a candidate SNP study

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Tobias Göllner

2015-08-01

Full Text Available Dopamine is a major neurotransmitter in the human brain and is associated with various diseases. Schizophrenia, for example, is treated by blocking the dopamine receptors type 2. Shaner, Miller & Mintz (2004 stated that schizophrenia was the low fitness variant of a highly variable mental trait. We therefore explore whether the dopamine receptor 2 gene (DRD2 underwent any selection processes. We acquired genotype data of the 1,000 Genomes project (phase I, which contains 1,093 individuals from 14 populations. We included single nucleotide polymorphisms (SNPs with two minor allele frequencies (MAFs in the analysis: MAF over 0.05 and over 0.01. This is equivalent to 151 SNPs (MAF > 0.05 and 246 SNPs (MAF > 0.01 for DRD2. We used two different approaches (an outlier approach and a Bayesian approach to detect loci under selection. The combined results of both approaches yielded nine (MAF > 0.05 and two candidate SNPs (MAF > 0.01, under balancing selection. We also found weak signs for directional selection on DRD2, but in our opinion these were too weak to draw any final conclusions on directional selection in DRD2. All candidates for balancing selection are in the intronic region of the gene and only one (rs12574471 has been mentioned in the literature. Two of our candidate SNPs are located in specific regions of the gene: rs80215768 lies within a promoter flanking region and rs74751335 lies within a transcription factor binding site. We strongly encourage research on our candidate SNPs and their possible effects.

Rancang Bangun Aplikasi Pembayaran Sekolah Menggunakan Java Dan MySQL Berbasis Client Server Di SMA Yos Sudarso Cilacap

OpenAIRE

Usada, Elisa; Isnawati, Anggun Fitrian; Fatimah, Dewi

2010-01-01

SMA Yos Sudarso merupakan salah satu sekolah yang sudah memanfaatkan komputer  untuk menyelesaikan berbagai macam tugas, tetapi pemanfaatannya masih belum maksimal karena ada bagian administrasi yang masih menggunakan metode manual, yaitu pada administrasi pembayaran. Penelitian ini  berusaha membuat sebuah aplikasi client server berteknologi JAVA dan MySQL untuk mengelola data pembayaran sekolah meliputi pembayaran SPP, pembayaran uang gedung serta pembayaran ujian. Metode waterfal...

PEMBELAJARAN MENULIS TEKS PIDATO DAN BERPIDATO KELAS X DI SMA NEGERI 3 SUKOHARJO

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Jaka Santosa

2016-02-01

Full Text Available This study has four aims, (1 the procedure of learning to write text to speech and speech in the classroom, (2 learning strategies and what the media writes text to speech and speech in the classroom, (3 student activity in learning to write text to speech and speech in the classroom, and (4 learning outcomes writing text to speech and speech. This includes descriptive qualitative research which took place in SMA Negeri 3 Sukoharjo. Data in the form of words and actions. Sources of data obtained from sources, events, and documents. Informant is Indonesian teachers and students. Events are learning activities Indonesian X1 class 2nd semester of academic year 2012/2013. The document in question is a document relating to the teaching of writing. Data collection techniques were interviews, observation, and documentary. Research findings in the field, among others, (1 the learning procedure by submitting a text to speech material on speech. Then compose the theme is developed into a framework and final drafting speeches, (2 application of learning strategies to write text to speech and speech with the approach that has been programmed patterns , the approach of process skills and communicative approach, (3 students activate in learning writing text to speech and speech have been carried out by providing learning facilities and trust management using effective learning infrastructure, (4 learning to write text to speech and speech by using the approach of process skills and communicative approaches undertaken by teachers Indonesian subjects in SMA Negeri 3 Sukoharjo obtain following result, students who earn good grades for writing text to speech 80 % and 88 % speech practice, then students who received grades enough to write the speech 20 % and 3 % speech practice, and students who obtain less value to the writing of the speech is not there, to practice speech while there were 9 % .

Mesoscale simulation of elastocaloric cooling in SMA films

International Nuclear Information System (INIS)

Wendler, Frank; Ossmer, Hinnerk; Chluba, Christoph; Quandt, Eckhard; Kohl, Manfred

2017-01-01

A model for the evolution of the mechanical and thermal properties of shape memory alloy (SMA) films during elastocaloric cycling is developed and compared with experiments. The focus is on Ti-Ni-Cu-Co films of 20 μm thickness showing ultra-low fatigue properties. The films undergo a highly localized pseudoelastic transformation under tensile load cycling featuring strain and temperature band patterns that depend on the loading conditions. The corresponding temperature change is of special interest for film-based elastocaloric cooling applications. Starting from a thermodynamics-based Gibbs free energy model comprising mechanical and chemical contributions, we include a martensite-austenite interface free energy term, for which formulations from a phase-field model are adapted. A 3D continuum mechanics description is modified to treat plane stress conditions appropriate for polycrystalline thin films. The nucleation mechanism of strain bands under dynamic loading is described by introducing a spatial random distribution of the transformation stress barriers reflecting the degree of material inhomogeneity. Heat transfer due to conduction and convection is taken into account. The simulations predict the correlated mechanical and thermal local response of the films including band formation and evolution, tilt angle as well as strain-rate dependence. Macroscopic stress-strain characteristics and thermal evolution curves well represent the experimental results.

OPTIMALISASI PENERAPAN METODE DISKUSI KELOMPOK UNTUK MENINGKATKAN HASIL BELAJAR EKONOMI DENGAN MATERI POKOK EKONOMI DAN SISTEM EKONOMI PADA SISWA KELAS X.3 SEMESTER SATU SMA NEGERI 3 SUKOHARJO TAHUN PELAJARAN 2014/2015

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Rochmiatun Rochmiatun

2017-02-01

Full Text Available The research aim was to describe the improvement of grade X.3 SMA N 3 (State Senior High School student’s economic learning outcome through group discussion method. The respondents of this research were 32 Grade X.3 students of SMA N 3 Sukoharjo. The research was conducted in two cycles, every cycle had four steps. The steps were (1 planning, (2 acting, (3 observing, (4 reflecting. The results of this action research were divided in two cycles.  In the first, cycle students average score was 70,31 higher than before. In the second cycle, students average score was 79,59. Based on those results, the implementation of group discussion method improved the learning outcome of grade X.3 students of SMA N 3 Sukoharjo in the economic subject. Keywords : Group Discussion Method, Learning Outcome, Economic

Dysfunction of the neuromuscular junction in spinal muscular atrophy types 2 and 3.

Science.gov (United States)

Wadman, Renske I; Vrancken, Alexander F J E; van den Berg, Leonard H; van der Pol, W Ludo

2012-11-13

Spinal muscular atrophy (SMA) is pathologically characterized by degeneration of anterior horn cells. Recent observations in animal models of SMA and muscle tissue from patients with SMA suggest additional abnormalities in the development and maturation of the neuromuscular junction. We therefore evaluated neuromuscular junction function in SMA with repetitive nerve stimulation. In this case-control study, repetitive nerve stimulation was performed in 35 patients with SMA types 2, 3, and 4, 20 healthy controls, and 5 controls with motor neuron disease. Pathologic decremental responses (>10%) during 3-Hz repetitive nerve stimulation were observed in 17 of 35 patients (49%) with SMA types 2 and 3, but not in healthy controls or controls with motor neuron disease. None of the patients or controls had an abnormal incremental response of >60%. The presence of an abnormal decremental response was not specific for the type of SMA, nor was it associated with compound muscle action potential amplitude, clinical scores, or disease duration. Two of 4 patients with SMA type 3 who tried pyridostigmine reported increased stamina. These data suggest dysfunction of the neuromuscular junction in patients with SMA types 2 and 3. Therefore, drugs that facilitate neuromuscular transmission are candidate drugs for evaluation in carefully designed, placebo-controlled, clinical trials.

Pilot Study for Investigating the Cyclic Behavior of Slit Damper Systems with Recentering Shape Memory Alloy (SMA Bending Bars Used for Seismic Restrainers

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Junwon Seo

2015-07-01

Full Text Available Although the steel slit dampers commonly utilized for aseismic design approach can dissipate considerable energy created by the yielding of base materials, large residual deformation may happen in the entire frame structure. After strong external excitation, repair costs will be incurred in restoring a structure to its original condition and to replace broken components. For this reason, alternative recentering devices characterized by smart structures, which mitigate the damage for such steel energy dissipation slit dampers, are developed in this study. These devices, feasibly functioning as seismic restrainers, can be improved by implementing superelastic shape memory alloy (SMA bending bars in a parallel motion with the steel energy-dissipating damper. The bending bars fabricated with superelastic SMAs provide self-centering forces upon unloading, and accordingly contribute to reducing permanent deformation in the integrated slit damper system. The steel slit dampers combined with the superelastic SMA bending bars are evaluated with respect to inelastic behavior as simulated by refined finite element (FE analyses. The FE slit damper models subjected to cyclic loads are calibrated to existing test results in an effort to predict behavior accurately. The responses of the proposed slit damper systems are compared to those of the conventionally used slit damper systems. From the analysis results, it is concluded that innovative steel slit dampers combined with superelastic SMA bending bars generate remarkable performance improvements in terms of post-yield strength, energy dissipation, and recentering capability.

Kurikulum Tersembunyi Lingkungan di dalam Materi Energi Terbarukan untuk Fisika SMA

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Desnita Desnita

2015-12-01

Full Text Available Abstract Renewable energy resources education, in essence, is the treatment of various topics and issues related to enewable energy resources and technologies as an environmental hidden curriculum in physics education at Senior High School. Based on the statement, environmental Hidden Curriculum in teaching physics concept, especially renewable energy resource was developed. Used research and development method, with step: need assessment, development theoretic models, validation, trial, and revision. The development result is a curriculum with contain: concept of green energy renewal resource and waste cooking oil as a kind of the resources, producing process, and learning strategies to implementation the curriculum. Implementation as trial this curriculum was conducted at a senior high school in South of Jakarta. Didactic exploration improves the learning process, link or integration in physics concept, when worksheets were used in the physics lab and multimedia system. The worksheet content are picture, video, and text or article about green renewable energy resources. Used project based learning and cooperative learning, using the worksheet was improve not only cognitive aspect of the student, but also their skill and attitude to save environmental. Kata-kata Kunci: environmental hidden curricullum, green renewable energy resources, learning strategies. Abstrak Inti dari pendidikan tentang sumber energi terbarukan adalah ujicoba terhadap sejumlah topik dan isu yang terkait dengan sumber energi terbarukan ramah lingkungan dan teknologinya sebagai sebuah kurikulum tersembunyi dalam pendidikan fisika pada tingkat SMA. Berdasarkan alasan tersebut, telah dikembangkan kurikulum lingkungan yang tersembunyi di dalam mengajar konsep fisika, khususnya sumber energi ramah lingkungan. Hasil pengembangan adalah kurikulum yang berisi konsep sumber energi terbarukan ramah lingkungan dan minyak jelanta sebagai salah satu jenisnya, proses produksi, dan

The Stanford Microsurgery and Resident Training (SMaRT) Scale: validation of an on-line global rating scale for technical assessment.

Science.gov (United States)

Satterwhite, Thomas; Son, Ji; Carey, Joseph; Echo, Anthony; Spurling, Terry; Paro, John; Gurtner, Geoffrey; Chang, James; Lee, Gordon K

2014-05-01

We previously reported results of our on-line microsurgery training program, showing that residents who had access to our website significantly improved their cognitive and technical skills. In this study, we report an objective means for expert evaluators to reliably rate trainees' technical skills under the microscope, with the use of our novel global rating scale. "Microsurgery Essentials" (http://smartmicrosurgery.com) is our on-line training curriculum. Residents were randomly divided into 2 groups: 1 group reviewed this online resource and the other did not. Pre- and post-tests consisted of videotaped microsurgical sessions in which the trainee performed "microsurgery" on 3 different models: latex glove, penrose drain, and the dorsal vessel of a chicken foot. The SMaRT (Stanford Microsurgery and Resident Training) scale, consisting of 9 categories graded on a 5-point Likert scale, was used to assess the trainees. Results were analyzed with ANOVA and Student t test, with P less than 0.05 indicating statistical significance. Seventeen residents participated in the study. The SMaRT scale adequately differentiated the performance of more experienced senior residents (PGY-4 to PGY-6, total average score=3.43) from less experienced junior residents (PGY-1 to PGY-3, total average score=2.10, P0.05). Additionally, junior residents who had access to our website showed a significant increase in their graded technical performance by 0.7 points when compared to residents who did not have access to the website who showed an improvement of only 0.2 points (P=0.01). Our SMaRT scale is valid and reliable in assessing the microsurgical skills of residents and other trainees. Current trainees are more likely to use self-directed on-line education because of its easy accessibility and interactive format. Our global rating scale can help ensure residents are achieving appropriate technical milestones.

Liver transplantation nearly normalizes brain spontaneous activity and cognitive function at 1 month: a resting-state functional MRI study.

Science.gov (United States)

Cheng, Yue; Huang, Lixiang; Zhang, Xiaodong; Zhong, Jianhui; Ji, Qian; Xie, Shuangshuang; Chen, Lihua; Zuo, Panli; Zhang, Long Jiang; Shen, Wen

2015-08-01

To investigate the short-term brain activity changes in cirrhotic patients with Liver transplantation (LT) using resting-state functional MRI (fMRI) with regional homogeneity (ReHo) method. Twenty-six cirrhotic patients as transplant candidates and 26 healthy controls were included in this study. The assessment was repeated for a sub-group of 12 patients 1 month after LT. ReHo values were calculated to evaluate spontaneous brain activity and whole brain voxel-wise analysis was carried to detect differences between groups. Correlation analyses were performed to explore the relationship between the change of ReHo with the change of clinical indexes pre- and post-LT. Compared to pre-LT, ReHo values increased in the bilateral inferior frontal gyrus (IFG), right inferior parietal lobule (IPL), right supplementary motor area (SMA), right STG and left middle frontal gyrus (MFG) in patients post-LT. Compared to controls, ReHo values of post-LT patients decreased in the right precuneus, right SMA and increased in bilateral temporal pole, left caudate, left MFG, and right STG. The changes of ReHo in the right SMA, STG and IFG were correlated with change of digit symbol test (DST) scores (P brain activity of most brain regions with decreased ReHo in pre-LT was substantially improved and nearly normalized, while spontaneous brain activity of some brain regions with increased ReHo in pre-LT continuously increased. ReHo may provide information on the neural mechanisms of LT' effects on brain function.

Estimation of reservoir inflow in data scarce region by using Sacramento rainfall runoff model - A case study for Sittaung River Basin, Myanmar

Science.gov (United States)

Myo Lin, Nay; Rutten, Martine

2017-04-01

The Sittaung River is one of four major rivers in Myanmar. This river basin is developing fast and facing problems with flood, sedimentation, river bank erosion and salt intrusion. At present, more than 20 numbers of reservoirs have already been constructed for multiple purposes such as irrigation, domestic water supply, hydro-power generation, and flood control. The rainfall runoff models are required for the operational management of this reservoir system. In this study, the river basin is divided into (64) sub-catchments and the Sacramento Soil Moisture Accounting (SAC-SMA) models are developed by using satellite rainfall and Geographic Information System (GIS) data. The SAC-SMA model has sixteen calibration parameters, and also uses a unit hydrograph for surface flow routing. The Sobek software package is used for SAC-SMA modelling and simulation of river system. The models are calibrated and tested by using observed discharge and water level data. The statistical results show that the model is applicable to use for data scarce region. Keywords: Sacramento, Sobek, rainfall runoff, reservoir

Gambaran Perilaku Remaja Terhadap Penggunaan Earphone Pada Siswa SMA Negeri Kota Padang

Directory of Open Access Journals (Sweden)

Tiara Rahma Zain

2016-09-01

Full Text Available AbstrakEarphone adalah alat yang digunakan untukmendengarkan musik dari telepon genggam dan perangkat audio lainnya.Sebuah survey yang dilakukan oleh American Speech Languageand Hearing Association (2006 menemukan bahwa remaja lebih banyak menggunakan perangkat dengar pribadidengan volume keras dan dalam waktu yang lama. Penelitian ini bertujuan untuk mengetahui gambaran perilaku remaja terhadap pengunaan earphone pada siswa SMA Negeri Kota PadangPenelitian ini dilakukan dengan metode deskriptif pada siswa SMAN Negeri Kota Padang yang berjumlah 13.105 orang.Didapatkan sampel berjumlah 427 orang, pengambilan sampel dilakukan dengan teknik Cluster Sampling.Data diambil dengan menggunakan kuesioner.Analisis data menggunakan analisis univarat dengan menggunakan program SPSS (Statistical Product and Service Solution 21.00 for Windows.                Hasil didapatkan proporsi pengguna earphone pada siswa SMA Negeri Kota Padangberjumlah 83,6%. Perilaku siswa dibagi menjadi 3 kategori yaitu pengetahuan, sikap dan tindakan. Hasilnya didapatkan siswa tersebut memiliki pengetahuan dan sikap yang baik terhadap penggunaan earphone dengan persentase 93,4% dan 80,9%. Tindakan siswa ketika menggunakan earphone cukup baik dengan persentasi 66,3%.                Kesimpulan penelitian ini adalah sebagian besar siswa SMA Negeri Kota Padang menggunakan earphone.Siswa tersebut memiliki pengetahuan yang baik mengenai dampak penggunaan earphone dan cara pencegahannya. Siswa juga memiliki sikap yang baik terhadap penggunaan earphone dan bertindak cukup baik ketika menggunakan earphone.Kata Kunci :Earphone, remaja, perilaku AbstractEarphone is a device that used for listening music from their mobile phone and other devices. A survey conducted by American Speech Languageand Hearing Association (2006 found that many teenagers use their personal audio device with maximum volume within a long time. This research aims to describe the teenager

Warm Debris Disk Candidates from WISE

Science.gov (United States)

Padgett, Deborah; Stapelfeldt, Karl; Liu, Wilson; Leisawitz, David

2011-01-01

The Wide Field Infrared Survey Explorer (WISE) has just completed a sensitive all-sky survey in photometric bands at 3.4, 4.6, 12, and 22 microns. We report on a preliminary investigation of main sequence Hipparcos and Tycho catalog stars with 22 micron emission in excess of photospheric levels. This warm excess emission traces material in the circumstellar region likely to host terrestrial planets and is preferentially found in young systems with ages warm debris disk candidates are detected among FGK stars and 150 A stars within 120 pc. We are in the process of obtaining spectra to determine spectral types and activity level of these stars and are using HST, Herschel and Keck to characterize the dust, multiplicity, and substellar companions of these systems. In this contribution, we will discuss source selection methods and individual examples from among the WISE debris disk candidates.

Achieving dynamic switchable filter based on a transmutable metasurface using SMA

Science.gov (United States)

Chen, Xin; Gao, Jinsong; Kang, Bonan

2017-09-01

We propose a switchable filter composed of transmutable array using shape memory alloys (SMA). It could exhibit a temperature induced morphology change spontaneously like the biological excitability, acting as a shutter that allows the incident energy to be selectively transmitted or reflected with in excess of 12dB isolation at the certain frequencies for both polarizations. Equivalent circuit models describe the operational principle qualitatively and the switching effect is underpinned by the full-wave analysis. A further physical mechanism is shown by contrasting the distributions of electric field and surface current on the surface at the same frequency for the two working modes. The experimental results consist with the theoretical simulations, indicating that the metasurface could serve as one innovative solution for manipulating the electromagnetic waves and enlighten the next generation of advanced electromagnetic materials with more freedom in the processes of design and manufacturing.

Achieving dynamic switchable filter based on a transmutable metasurface using SMA

Directory of Open Access Journals (Sweden)

Xin Chen

2017-09-01

Full Text Available We propose a switchable filter composed of transmutable array using shape memory alloys (SMA. It could exhibit a temperature induced morphology change spontaneously like the biological excitability, acting as a shutter that allows the incident energy to be selectively transmitted or reflected with in excess of 12dB isolation at the certain frequencies for both polarizations. Equivalent circuit models describe the operational principle qualitatively and the switching effect is underpinned by the full-wave analysis. A further physical mechanism is shown by contrasting the distributions of electric field and surface current on the surface at the same frequency for the two working modes. The experimental results consist with the theoretical simulations, indicating that the metasurface could serve as one innovative solution for manipulating the electromagnetic waves and enlighten the next generation of advanced electromagnetic materials with more freedom in the processes of design and manufacturing.

The Usher syndrome in the Lebanese population and further refinement of the USH2A candidate region.

Science.gov (United States)

Saouda, M; Mansour, A; Bou Moglabey, Y; El Zir, E; Mustapha, M; Chaib, H; Nehmé, A; Mégarbané, A; Loiselet, J; Petit, C; Slim, R

1998-08-01

Usher syndrome (USH) is an autosomal-recessive disease characterized by neurosensory deafness and progressive retinitis pigmentosa. So far, three clinical types of Usher syndrome have been defined, and are caused by defects at more than eight loci. We report the linkage analysis of seven Lebanese families with Usher syndrome, two with type I (USH1) and five with type II (USH2). We demonstrate that one family is linked to the USH1C locus, a rare form of USH1 only reported in the French Acadian population. Linkage analysis of the five USH2 families with recently mapped loci allowed us to reduce the USH2A candidate region to a very small interval flanked by D1S2646/D1S2629 and D1S2827. Furthermore, haplotype comparison between the different families suggests a founder effect for the USH2A mutation among the different Lebanese ethnic groups, while a genetic heterogeneity is noted for Usher syndrome type I.

New VVV Survey Globular Cluster Candidates in the Milky Way Bulge

Energy Technology Data Exchange (ETDEWEB)

Minniti, Dante; Gómez, Matías [Departamento de Física, Facultad de Ciencias Exactas, Universidad Andrés Bello, Av. Fernandez Concha 700, Las Condes, Santiago (Chile); Geisler, Douglas; Fernández-Trincado, Jose G. [Departamento de Astronomía, Casilla 160-C, Universidad de Concepción, Casilla 160-C, Concepción (Chile); Alonso-García, Javier; Beamín, Juan Carlos; Borissova, Jura; Catelan, Marcio; Ramos, Rodrigo Contreras; Kurtev, Radostin; Pullen, Joyce [Instituto Milenio de Astrofísica, Santiago (Chile); Palma, Tali; Clariá, Juan J. [Observatorio Astronómico, Universidad Nacional de Córdoba, Laprida 854, Córdoba (Argentina); Cohen, Roger E. [Space Telescope Science Institute, 2700 San Martin Drive, Baltimore (United States); Dias, Bruno [European Southern Observatory, Alonso de Cordova 3107, Vitacura, Santiago (Chile); Hempel, Maren [Pontificia Universidad Católica de Chile, Instituto de Astrofísica, Av. Vicuña Mackenna 4860, Santiago (Chile); Ivanov, Valentin D. [European Southern Observatory, Karl-Schwarszchild-Str. 2, D-85748 Garching bei Muenchen (Germany); Lucas, Phillip W. [Dept. of Astronomy, University of Hertfordshire, Hertfordshire (United Kingdom); Moni-Bidin, Christian; Alegría, Sebastian Ramírez [Instituto de Astronomía, Universidad Católica del Norte, Antofagasta (Chile); and others

2017-11-10

It is likely that a number of Galactic globular clusters remain to be discovered, especially toward the Galactic bulge. High stellar density combined with high and differential interstellar reddening are the two major problems for finding globular clusters located toward the bulge. We use the deep near-IR photometry of the VISTA Variables in the Vía Láctea (VVV) Survey to search for globular clusters projected toward the Galactic bulge, and hereby report the discovery of 22 new candidate globular clusters. These objects, detected as high density regions in our maps of bulge red giants, are confirmed as globular cluster candidates by their color–magnitude diagrams. We provide their coordinates as well as their near-IR color–magnitude diagrams, from which some basic parameters are derived, such as reddenings and heliocentric distances. The color–magnitude diagrams reveal well defined red giant branches in all cases, often including a prominent red clump. The new globular cluster candidates exhibit a variety of extinctions (0.06 < A {sub Ks} < 2.77) and distances (5.3 < D < 9.5 kpc). We also classify the globular cluster candidates into 10 metal-poor and 12 metal-rich clusters, based on the comparison of their color–magnitude diagrams with those of known globular clusters also observed by the VVV Survey. Finally, we argue that the census for Galactic globular clusters still remains incomplete, and that many more candidate globular clusters (particularly the low luminosity ones) await to be found and studied in detail in the central regions of the Milky Way.

Exclusion of candidate genes from the chromosome 1q juvenile glaucoma region and mapping of the peripheral cannabis receptor gene (CNR2) to chromosome 1

Energy Technology Data Exchange (ETDEWEB)

Sunden, S.L.F.; Nichols, B.E.; Alward, W.L.M. [Univ. of Iowa, Iowa City, IA (United States)] [and others

1994-09-01

Juvenile onset primary open angle glaucoma has been mapped by linkage to 1q21-q31. Several candidate genes were evaluated in the same family used to identify the primary linkage. Atrionatriuretic peptide receptor A (NPR1) and laminin C1 (LAMC1) have been previously mapped to this region and could putatively play a role in the pathogenesis of glaucoma. A third gene, the peripheral cannabis receptor (CNR2) was not initially mapped in humans but was a candidate because of the relief that cannabis affords some patients with primary open angle glaucoma. Microsatellites associated with NPR1 and LAMC1 revealed multiple recombinations in affected members of this pedigree. CNR2 was shown to be on chromosome 1 by PCR amplification of a 150 bp fragment of the 3{prime} untranslated region in monochromosomal somatic cell hybrids (NIGMS panel No. 2). These primers also revealed a two allele single strand conformation polymorphism which showed multiple recombinants with juvenile onset primary open angle glaucoma in large pedigrees, segregating this disorder. The marker was then mapped to 1p34-p36 by linkage, with the most likely location between liver alkaline phosphatase (ALPL) and alpha-L-1 fucosidase (FUCA1).

EnviroAtlas - Candidate Areas for Ecological Restoration for the Conterminous United States

Data.gov (United States)

U.S. Environmental Protection Agency — This EnviroAtlas dataset shows the candidate areas for ecological restoration, identified as close but geographically disjunct vegetated regions. Ecological...

ENU Mutagenesis in Mice Identifies Candidate Genes For Hypogonadism

Science.gov (United States)

Weiss, Jeffrey; Hurley, Lisa A.; Harris, Rebecca M.; Finlayson, Courtney; Tong, Minghan; Fisher, Lisa A.; Moran, Jennifer L.; Beier, David R.; Mason, Christopher; Jameson, J. Larry

2012-01-01

Genome-wide mutagenesis was performed in mice to identify candidate genes for male infertility, for which the predominant causes remain idiopathic. Mice were mutagenized using N-ethyl-N-nitrosourea (ENU), bred, and screened for phenotypes associated with the male urogenital system. Fifteen heritable lines were isolated and chromosomal loci were assigned using low density genome-wide SNP arrays. Ten of the fifteen lines were pursued further using higher resolution SNP analysis to narrow the candidate gene regions. Exon sequencing of candidate genes identified mutations in mice with cystic kidneys (Bicc1), cryptorchidism (Rxfp2), restricted germ cell deficiency (Plk4), and severe germ cell deficiency (Prdm9). In two other lines with severe hypogonadism candidate sequencing failed to identify mutations, suggesting defects in genes with previously undocumented roles in gonadal function. These genomic intervals were sequenced in their entirety and a candidate mutation was identified in SnrpE in one of the two lines. The line harboring the SnrpE variant retains substantial spermatogenesis despite small testis size, an unusual phenotype. In addition to the reproductive defects, heritable phenotypes were observed in mice with ataxia (Myo5a), tremors (Pmp22), growth retardation (unknown gene), and hydrocephalus (unknown gene). These results demonstrate that the ENU screen is an effective tool for identifying potential causes of male infertility. PMID:22258617

SUBMILLIMETER ARRAY AND SPITZER OBSERVATIONS OF BOK GLOBULE CB 17: A CANDIDATE FIRST HYDROSTATIC CORE?

Energy Technology Data Exchange (ETDEWEB)

Chen Xuepeng; Arce, Hector G.; Dunham, Michael M. [Department of Astronomy, Yale University, Box 208101, New Haven, CT 06520-8101 (United States); Zhang Qizhou; Bourke, Tyler L. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Launhardt, Ralf; Schmalzl, Markus; Henning, Thomas, E-mail: xuepeng.chen@yale.edu [Max Planck Institute for Astronomy, Koenigstuhl 17, D-69117 Heidelberg (Germany)

2012-06-01

We present high angular resolution Submillimeter Array (SMA) and Spitzer observations toward the Bok globule CB 17. SMA 1.3 mm dust continuum images reveal within CB 17 two sources with an angular separation of {approx}21'' ({approx}5250 AU at a distance of {approx}250 pc). The northwestern continuum source, referred to as CB 17 IRS, dominates the infrared emission in the Spitzer images, drives a bipolar outflow extending in the northwest-southeast direction, and is classified as a low-luminosity Class 0/I transition object (L{sub bol} {approx} 0.5 L{sub Sun }). The southeastern continuum source, referred to as CB 17 MMS, has faint dust continuum emission in the SMA 1.3 mm observations ({approx}6{sigma} detection; {approx}3.8 mJy), but is not detected in the deep Spitzer infrared images at wavelengths from 3.6 to 70 {mu}m. Its bolometric luminosity and temperature, estimated from its spectral energy distribution, are {<=}0.04 L{sub Sun} and {<=}16 K, respectively. The SMA CO (2-1) observations suggest that CB 17 MMS may drive a low-velocity molecular outflow ({approx}2.5 km s{sup -1}), extending in the east-west direction. Comparisons with prestellar cores and Class 0 protostars suggest that CB 17 MMS is more evolved than prestellar cores but less evolved than Class 0 protostars. The observed characteristics of CB 17 MMS are consistent with the theoretical predictions from radiative/magnetohydrodynamical simulations of a first hydrostatic core, but there is also the possibility that CB 17 MMS is an extremely low luminosity protostar deeply embedded in an edge-on circumstellar disk. Further observations are needed to study the properties of CB 17 MMS and to address more precisely its evolutionary stage.

THE EFFORT TO IMPROVE TEACHERS’PERFORMANCE OF SMA TMI ROUDLATUL QUR’AN IN COMPOSING LESSON PLAN AND EVALUATION INSTRUMENT OF CHARACTER EDUCATION THROUGH WORKSHOP ACADEMIC YEAR 2015/2016

Directory of Open Access Journals (Sweden)

Budi Raharjo

2015-10-01

Full Text Available Abstract: Difficulties found in Senior High School (SMA TMI Roudlatul Qur’an, teachers were not able to integrate character value into their lesson plan and to identify which behaviour must be success indicators of character education. Out of 18 Character value existed, the measurement of students’success as the better change of their behaviour, some only covering observation and lack of triangulation consideration to more accountable result. Worskhop potentially becomes one of the ways to up grade teachers’performance in determining the instrument of character value education, at the same time, train them the way composing lesson plan which integrates character education. This school action research was aimed to carry out workshop at SMA TMI Roudlatul Qur’an of Metro Municipal City, to improve teachers’performance in composing evaluation instrumen of value character education, to improve teachers’performance in composing integrated character value education.The research took place at SMA TMI Roudlatul Qur’an, located at Mulyojati, Metro Barat, Metro Municipal City. It was done in odd semester, continually to one month. Started in early Academic Year 2015/2016, July to August.The researcher concluded that teachers of SMA TMI Roudlatul Qur’an improved their performance well in composing evaluation instrument of value character education and integrated value character lesson plan through workshop. Facts: Workshop process was considered fair 11 teachers, good by 16 teachers, and very good by 12 teachers. At cycle II, the performance of composing evaluation instrument of character education showed 11 teachers were less sufficient performance, 16 teachers were good performance, and 12 teachers were very good. And the performance of composing integrated character value at cycle II showed 8 moderate teachers, 19 good teachers, and 12 excellent teachers. Key words: Workshop, Lesson Plan, Character Education Evaluation

Citizen Candidates Under Uncertainty

OpenAIRE

Eguia, Jon X.

2005-01-01

In this paper we make two contributions to the growing literature on "citizen-candidate" models of representative democracy. First, we add uncertainty about the total vote count. We show that in a society with a large electorate, where the outcome of the election is uncertain and where winning candidates receive a large reward from holding office, there will be a two-candidate equilibrium and no equilibria with a single candidate. Second, we introduce a new concept of equilibrium, which we te...

ECONOMIC GROWTH IN SOUTH EASTERN EUROPE: AN INVESTIGATION FOR SIX EU CANDIDATE AND POTENTIAL CANDIDATE COUNTRIES

Directory of Open Access Journals (Sweden)

Ileana Tache

2017-08-01

Full Text Available The South Eastern European region (SEE has seen major beneficial transformation in the recent years. Romania and Bulgaria in 2007 and Croatia in 2013 became members of the European Union and registered significant economic growth rates. This paper investigates some important factors that influence economic growth in 6 EU candidate and potential candidate countries (Albania, Bosnia and Herzegovina, Kosovo, Former Yugoslav Republic of Macedonia, Montenegro and Serbia and offers to policy makers in those countries key insights for stimulating the economy. The paper proposes a dynamic growth model which will be developed using the Quasi-maximum likelihood (QML estimation. This model is suited for this type of analysis because of the small T sample and also to cope with missingness. The results indicate that nine out of the fourteen variables were statistically significant. The number of non-resident tourists, the number of passenger cars, the number of children in pre-primary and primary-education are positive factors for economic growth. In contrast, government debt, inflation, all energy imports, railway transportation and primary production of coal and lignite are hindering development.

Shape memory alloy wire-based smart natural rubber bearing

International Nuclear Information System (INIS)

Hedayati Dezfuli, F; Shahria Alam, M

2013-01-01

In this study, two types of smart elastomeric bearings are presented using shape memory alloy (SMA) wires. Due to the unique characteristics of SMAs, such as the superelastic effect and the recentering capability, the residual deformation in SMA-based natural rubber bearings (SMA-NRBs) is significantly reduced whereas the energy dissipation capacity is increased. Two different configurations of SMA wires incorporated in elastomeric bearings are considered. The effect of several parameters, including the shear strain amplitude, the type of SMA, the aspect ratio of the base isolator, the thickness of SMA wire, and the amount of pre-strain in the wires on the performance of SMA-NRBs is investigated. Rubber bearings are composed of natural rubber layers bonded to steel shims as reinforcement. Results show that ferrous SMA wire, FeNiCuAlTaB, with 13.5% superelastic strain and a very low austenite finish temperature (−62 °C), is the best candidate to be used in SMA-NRBs subjected to high shear strain amplitudes. In terms of the lateral flexibility and wire strain level, the smart rubber bearing with a cross configuration of SMA wires is more efficient. Moreover, the cross configuration can be implemented in high-aspect-ratio elastomeric bearings since the strain induced in the wire does not exceed the superelastic range. When cross SMA wires with 2% pre-strain are used in a smart NRB, the dissipated energy is increased by 74% and the residual deformation is decreased by 15%. (paper)

Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation.

Science.gov (United States)

Kuony, Alison; Michon, Frederic

2017-01-01

As an element of the lacrimal apparatus, the lacrimal gland (LG) produces the aqueous part of the tear film, which protects the eye surface. Therefore, a defective LG can lead to serious eyesight impairment. Up to now, little is known about LG morphogenesis and subsequent maturation. In this study, we delineated elements of the cellular and molecular events involved in LG formation by using three epithelial markers, namely aSMA, Krt14, and Krt19. While aSMA marked a restricted epithelial population of the terminal end buds (TEBs) in the forming LG, Krt14 was found in the whole embryonic LG epithelial basal cell layer. Interestingly, Krt19 specifically labeled the presumptive ductal domain and subsequently, the luminal cell layer. By combining these markers, the Fucci reporter mouse strain and genetic fate mapping of the Krt14 + population, we demonstrated that LG epithelium expansion is fuelled by a patterned cell proliferation, and to a lesser extent by epithelial reorganization and possible mesenchymal-to-epithelial transition. We pointed out that this epithelial reorganization, which is associated with apoptosis, regulated the lumen formation. Finally, we showed that the inhibition of Notch signaling prevented the ductal identity from setting, and led to a LG covered by ectopic TEBs. Taken together our results bring a deeper understanding on LG morphogenesis, epithelial domain identity, and organ expansion.

Candidate Gense of Juvenile Hypertension in the Region of the Major Histo-Compatibility System

Czech Academy of Sciences Publication Activity Database

Mazura, I.; Nutsu-Mazura, F.; Bláha, P.; Bendlová, B.; Včelák, J.; Palyzová, D.; Zvárová, Jana

2002-01-01

Roč. 26, suppl. 1 (2002), s. 84 ISSN 0307-0565. [International Congress on Obesity /9./. 24.08.2002-29.08.2002, Sao Paulo] R&D Projects: GA MZd NB6635; GA MŠk LN00B107 Keywords : juvenile hypertension * candidate genes * statistics Subject RIV: BB - Applied Statistics, Operational Research

Construção de um trecho experimental em SMA usando bagaço de cana-de-açúcar como aditivo

Directory of Open Access Journals (Sweden)

Cláudio Luiz Dias Leal

2013-05-01

Full Text Available Pesquisadores da área de pavimentação têm buscado soluções apropriadas para melhoria do desempenho de nossos pavimentos frente às modificações dos veículos comerciais. O Stone Matrix Asphalt (SMA é uma excelente alternativa para elevar o desempenho dos pavimentos brasileiros. Essa mistura asfáltica, com granulometria descontínua e cerca de 70% de agregado graúdo, otimiza o contato grão a grão, aumentando consideravelmente o desempenho estrutural da camada de rolamento, principalmente quanto às deformações permanentes. Misturas do tipo SMA, em função do alto teor de ligante asfáltico, necessitam de fibras como aditivo estabilizante para que não haja segregação ou exsudação durante o processo de mistura e espalhamento. A produção de açúcar e álcool gera cerca de 270 quilogramas de bagaço por tonelada de cana-de-açúcar moída. A maior parte do bagaço é queimada nas caldeiras das usinas para produção de energia térmica ou elétrica. Estima-se que aproximadamente 20% do bagaço não é queimado. Esta pesquisa tem como objetivo principal estudar o aproveitamento do bagaço de cana-de-açúcar como aditivo estabilizante, nas misturas asfálticas do tipo SMA, produzida com asfalto modificado por borracha moída de pneus, em substituição à fibra de celulose. Para verificação dessa hipótese foi feito um estudo laboratorial e um trecho experimental foi construído para avaliação da mistura em serviço.

The Effect of Buzz Group Technique and Clustering Technique in Teaching Writing at the First Class of SMA HKBP I Tarutung

Science.gov (United States)

Pangaribuan, Tagor; Manik, Sondang

2018-01-01

This research held at SMA HKBP 1 Tarutung North Sumatra on the research result of test XI[superscript 2] and XI[superscript 2] students, after they got treatment in teaching writing in recount text by using buzz group and clustering technique. The average score (X) was 67.7 and the total score buzz group the average score (X) was 77.2 and in…

Time evolution in static β-phase dynamic β-martensite coexistence (Cu-Zn-Al SMA)

International Nuclear Information System (INIS)

Isalgue, A.; Lovey, F.C.

1995-01-01

The application of a SMA implies an accurate knowledge about the eventual time - behavior of the alloys. The effects of quenching and micro-heatings were studied by calorimetric and resistance measurements and the β-martensite coexistence by stress - strain - temperature - time observations. Experimental analysis was performed using copper based single crystals (Cu-Zn-Al, e/a ∼1.48 e/a with Ms below room temperature). The phenomenological behavior establishes several time constants for each evolution. A change ΔT of temperature of the parent phase near 300 K induces an asymptotic time evolution on M S near 11 per cent. The parent to martensite coexistence produces an evolution of the equilibrium temperature (near 0.5 K) linked to the existence of an interface. (orig.)

Physical mapping of the major early-onset familial Alzheimer`s disease locus on chromosome 14 and analysis of candidate gene sequences

Energy Technology Data Exchange (ETDEWEB)

Tanzi, R.E.; Romano, D.M.; Crowley, A.C. [Harvard Medical School, Charlestown, MA (United States)] [and others

1994-09-01

Genetic studies of kindreds displaying evidence for familial AD (FAD) have led to the localization of gene defects responsible for this disorder on chromosomes 14, 19, and 21. A minor early-onset FAD gene on chromosome 21 has been identified to enode the amyloid precursor protein (APP), and the late-onset FAD susceptibility locus on chromosome 19 has been shown to be in linkage disequilibrium with the E4 allele of the APOE gene. Meanwhile, the locus responsible for the major form of early-onset FAD on chromosome 14q24 has not yet been identified. By recombinational analysis, we have refined the minimal candidate region containing the gene defect to approximately 3 megabases in 14q24. We will describe our laboratory`s progress on attempts to finely localize this locus, as well as test known candidate genes from this region for either inclusion in the minimal candidate region or the presence of pathogenic mutations. Candidate genes that have been tested so far include cFOS, heat shock protein 70 member (HSF2A), transforming growth factor beta (TGFB3), the trifunctional protein C1-THF synthase (MTHFD), bradykinin receptor (BR), and the E2k component of a-ketoglutarate dehydrogenase. HSP2A, E2k, MTHFD, and BR do not map to the current defined minimal candidate region; however, sequence analysis must be performed to confirm exclusion of these genes as true candidates. Meanwhile, no pathogenic mutations have yet been found in cFOS or TGFB3. We have also isolated a large number of novel transcribed sequences from the minimal candidate region in the form of {open_quotes}trapped exons{close_quotes} from cosmids identified by hybridization to select YAC clones; we are currently in the process of searching for pathogenic mutations in these exons in affected individuals from FAD families.

An innovative ultra-capacitor driven shape memory alloy actuator with an embedded control system

International Nuclear Information System (INIS)

Li, Peng; Song, Gangbing

2014-01-01

In this paper, an innovative ultra-capacitor driven shape memory alloy (SMA) actuator with an embedded control system is proposed targeting high power high-duty cycle SMA applications. The ultra-capacitor, which is capable of delivering massive amounts of instantaneous current in a compact dimension for high power applications, is chosen as the main component of the power supply. A specialized embedded system is designed from the ground up to control the ultra-capacitor driven SMA system. The control of the ultra-capacitor driven SMA is different from that of a regular constant voltage powered SMA system in that the energy and the voltage of the ultra-capacitor decrease as the system load increases. The embedded control system is also different from a computer-based control system in that it has limited computational power, and the control algorithm has to be designed to be simple while effective so that it can fit into the embedded system environment. The problem of a variable voltage power source induced by the use of the ultra-capacitor is solved by using a fuzzy PID (proportional integral and derivative) control. The method of using an ultra-capacitor to drive SMA actuators enabled SMA as a good candidate for high power high-duty cycle applications. The proposed embedded control system provides a good and ready-to-use solution for SMA high power applications. (paper)

Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies

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Gonzalez-Neira Anna

2007-08-01

Full Text Available Abstract Background The recent development of new high-throughput technologies for SNP genotyping has opened the possibility of taking a genome-wide linkage approach to the search for new candidate genes involved in heredity diseases. The two major breast cancer susceptibility genes BRCA1 and BRCA2 are involved in 30% of hereditary breast cancer cases, but the discovery of additional breast cancer predisposition genes for the non-BRCA1/2 breast cancer families has so far been unsuccessful. Results In order to evaluate the power improvement provided by using SNP markers in a real situation, we have performed a whole genome screen of 19 non-BRCA1/2 breast cancer families using 4720 genomewide SNPs with Illumina technology (Illumina's Linkage III Panel, with an average distance of 615 Kb/SNP. We identified six regions on chromosomes 2, 3, 4, 7, 11 and 14 as candidates to contain genes involved in breast cancer susceptibility, and additional fine mapping genotyping using microsatellite markers around linkage peaks confirmed five of them, excluding the region on chromosome 3. These results were consistent in analyses that excluded SNPs in high linkage disequilibrium. The results were compared with those obtained previously using a 10 cM microsatellite scan (STR-GWS and we found lower or not significant linkage signals with STR-GWS data compared to SNP data in all cases. Conclusion Our results show the power increase that SNPs can supply in linkage studies.

A novel live-attenuated vaccine candidate for mayaro Fever.

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William J Weise

2014-08-01

Full Text Available Mayaro virus (MAYV is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we capitalized on an IRES-based approach to develop a live-attenuated MAYV vaccine candidate. Testing in infant, immunocompetent as well as interferon receptor-deficient mice demonstrated a high degree of attenuation, strong induction of neutralizing antibodies, and efficacy against lethal challenge. This vaccine strain was also unable to infect mosquito cells, a major safety feature for a live vaccine derived from a mosquito-borne virus. Further preclinical development of this vaccine candidate is warranted to protect against this important emerging disease.

Defining the Sequence Elements and Candidate Genes for the Coloboma Mutation.

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Elizabeth A. Robb

Full Text Available The chicken coloboma mutation exhibits features similar to human congenital developmental malformations such as ocular coloboma, cleft-palate, dwarfism, and polydactyly. The coloboma-associated region and encoded genes were investigated using advanced genomic, genetic, and gene expression technologies. Initially, the mutation was linked to a 990 kb region encoding 11 genes; the application of the genetic and genomic tools led to a reduction of the linked region to 176 kb and the elimination of 7 genes. Furthermore, bioinformatics analyses of capture array-next generation sequence data identified genetic elements including SNPs, insertions, deletions, gaps, chromosomal rearrangements, and miRNA binding sites within the introgressed causative region relative to the reference genome sequence. Coloboma-specific variants within exons, UTRs, and splice sites were studied for their contribution to the mutant phenotype. Our compiled results suggest three genes for future studies. The three candidate genes, SLC30A5 (a zinc transporter, CENPH (a centromere protein, and CDK7 (a cyclin-dependent kinase, are differentially expressed (compared to normal embryos at stages and in tissues affected by the coloboma mutation. Of these genes, two (SLC30A5 and CENPH are considered high-priority candidate based upon studies in other vertebrate model systems.

Defining the Human Macula Transcriptome and Candidate Retinal Disease Genes UsingEyeSAGE

Science.gov (United States)

Rickman, Catherine Bowes; Ebright, Jessica N.; Zavodni, Zachary J.; Yu, Ling; Wang, Tianyuan; Daiger, Stephen P.; Wistow, Graeme; Boon, Kathy; Hauser, Michael A.

2009-01-01

Purpose To develop large-scale, high-throughput annotation of the human macula transcriptome and to identify and prioritize candidate genes for inherited retinal dystrophies, based on ocular-expression profiles using serial analysis of gene expression (SAGE). Methods Two human retina and two retinal pigment epithelium (RPE)/choroid SAGE libraries made from matched macula or midperipheral retina and adjacent RPE/choroid of morphologically normal 28- to 66-year-old donors and a human central retina longSAGE library made from 41- to 66-year-old donors were generated. Their transcription profiles were entered into a relational database, EyeSAGE, including microarray expression profiles of retina and publicly available normal human tissue SAGE libraries. EyeSAGE was used to identify retina- and RPE-specific and -associated genes, and candidate genes for retina and RPE disease loci. Differential and/or cell-type specific expression was validated by quantitative and single-cell RT-PCR. Results Cone photoreceptor-associated gene expression was elevated in the macula transcription profiles. Analysis of the longSAGE retina tags enhanced tag-to-gene mapping and revealed alternatively spliced genes. Analysis of candidate gene expression tables for the identified Bardet-Biedl syndrome disease gene (BBS5) in the BBS5 disease region table yielded BBS5 as the top candidate. Compelling candidates for inherited retina diseases were identified. Conclusions The EyeSAGE database, combining three different gene-profiling platforms including the authors’ multidonor-derived retina/RPE SAGE libraries and existing single-donor retina/RPE libraries, is a powerful resource for definition of the retina and RPE transcriptomes. It can be used to identify retina-specific genes, including alternatively spliced transcripts and to prioritize candidate genes within mapped retinal disease regions. PMID:16723438

The Southern HII Region Discovery Survey: The Bright Catalog

Science.gov (United States)

Wenger, Trey V.; Dickey, John M.; Jordan, Christopher H.; Balser, Dana; Armentrout, William Paul; Anderson, Loren; Bania, Thomas; Dawson, Joanne; McClure-Griffiths, Naomi M.; Shea, Jeanine

2018-01-01

HII regions, the zones of ionized gas surrounding recently formed high-mass stars, are the archetypical tracers of Galactic structure. The census of Galactic HII regions in the Southern sky is vastly incomplete due to a lack of sensitive radio recombination line (RRL) surveys. The Southern HII Region Discovery Survey (SHRDS) is a 900-hour Australia Telescope Compact Array cm-wavelength RRL and continuum emission survey of hundreds of third and fourth quadrant Galactic HII region candidates. These candidates are identified in the Widefield Infrared Survey Explorer (WISE) Catalog of Galactic HII Regions based on coincident 10 micron (WISE) and 20 cm (Southern Galactic Plane Survey) emission. The SHRDS is an extension of HII Region Discovery Surveys in the Northern sky with the Green Bank Telescope and Arecibo Telescope which discovered ~800 new HII regions. In the first 500 hours of the SHRDS, we targeted the 249 brightest HII region candidates and 33 previously known HII regions. We discuss the data reduction, analysis, and preliminary results from this first stage of the survey.

Analytical Investigation of the Cyclic Behavior of Smart Recentering T-Stub Components with Superelastic SMA Bolts

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Junwon Seo

2017-09-01

Full Text Available Partially restrained (PR bolted T-stub connections have been widely used in replacement of established fully restrained (FR welded connections, which are susceptible to sudden brittle failure. These bolted T-stub connections can permit deformation, easily exceeding the allowable limit without any fracture because they are constructed with a design philosophy whereby the plastic deformation concentrates on bolt fasteners made of ductile steel materials. Thus, the PR bolted connections take advantage of excellent energy dissipation capacity in their moment and rotation behavior. However, a considerable amount of residual deformation may occur at the bolted connection subjected to excessive plastic deformation, thereby requiring additional costs to recover the original configuration. In this study, superelastic shape memory alloy (SMA bolts, which have a recentering capability upon unloading, are fabricated so as to solve these drawbacks, and utilized by replacing conventional steel bolts in the PR bolted T-stub connection. Instead of the full-scale T-stub connection, simplified T-stub components subjected to axial force are designed on the basis of a basic equilibrium theory that transfers the bending moment from the beam to the column and can be converted into equivalent couple forces acting on the beam flange. The feasible failure modes followed by corresponding response mechanisms are taken into consideration for component design with superelastic SMA bolts. The inelastic behaviors of such T-stub components under cyclic loading are simulated by advanced three-dimensional (3D finite element (FE analysis. Finally, this study suggests an optimal design for smart recentering T-stub components with respect to recentering and energy dissipation after observing the FE analysis results.

PENGGUNAAN BAHAN AJAR DENGAN PENDEKATAN ANDRAGOGI SEBAGAI UPAYA MENINGKATKAN KREATIVITAS DAN HASIL BELAJAR SISWA SMA RSBI

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M. Umriyah

2012-01-01

Full Text Available Andragogi merupakan teori pembelajaran orang dewasa. Konsep pembelajaran orang dewasa merupakan pembelajaran yang berpola non otoriter. Berdasarkan ciri-ciri biologis maupun psikologis sebagian besar siswa SMA telah memasuki usia dewasa, sehingga pendekatan andragogi agaknya lebih sesuai. Penelitian ini merupakan penelitian pengembangan yaitu mengembangkan bahan ajar dengan pendekatan andragogi, bertujuan untuk memperoleh bahan ajar yang dapat meningkatkan kreativitas dan hasil belajar siswa. Subyek penelitian adalah siswa  kelas X-2 SMA Islam Sudirman Ambarawa tahun pelajaran 2010/2011. Pengambilan data dilakukan dengan metode dokumentasi, observasi dan  test hasil belajar.  Hasil penelitian menunjukkan bahwa dengan digunakannya bahan ajar dengan pendekatan andragogi, skor kreativitas  dan hasil test kognitif siswa rata-rata meningkat.Andragogy is adult learning theory. Adult learning concept is learning activity that gets to pattern non authoritarian. Based on biological characteristics and also psychological a large part Senior High School students  have entered adult age, so pedagogy approach (education for children was not suitable anymore for them, it seems that andragogy (education for adult is more suitable. This research is development research which develop learning material in andragogy approach, has an aim to get a learning material that can develop creativity and studying result. The research is executed in X2 class at Sudirman Islamic Senior High School of Ambarawa, academic year 2010 / 2011 which is chosen bases random sampling. Data taking is done by documentation method, observation and learning result test.  Data analysis  indicate   an  improving  of average  value  in creativity and learning result.

PENGARUH PENERAPAN BELAJAR MANDIRI PADA MATERI EKOSISTEM TERHADAP KETERAMPILAN BERPIKIR KRITIS DAN KEMAMPUAN MEMECAHKAN MASALAH SISWA SMA DI KOTA METRO

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Anak Agung Oka

2010-11-01

Full Text Available The objective of this research was to know the effect of  alone learning to the critical thinking skill and problem solving ability in SMA Teladan 1 Metro. This research applied quasy experimental with non-equvalent control group design. The population of this research is allow students of class X SMA Teladan 1 Metro on academic year 2009/2010. The samples of this research were class XA as experimental (alone learning and class XB as control (conventional. The instrument of this research namely critical thinking and problem solving test. This research data are quantitative data consisted by score capacity critical thinking and problem solving ability to river ecosystem, collected on 15 january until 12 Juni 2010. Data were analysed by bilinear covariant statistical analysis (Ancova, continued with LSD test. The result of this research indicated that there were an effect of alone learning strategy toward the critical thinking skill and problem solving ability. Student with alone learning strategy having critical thinking higher 80,111% than conventional learning. Beside, student with alone learning strategy having 11,124% higher than convensional learning. Based on this research, the researcher suggest to the teacher that this strategy can implemented in biology learning.   Kata Kunci: Belajar Mandiri, Keterampilan Berpikir Kritis, Kemampuan Memecahkan Masalah.

Force Spectroscopy of the Plasmodium falciparum Vaccine Candidate Circumsporozoite Protein Suggests a Mechanically Pliable Repeat Region.

Science.gov (United States)

Patra, Aditya Prasad; Sharma, Shobhona; Ainavarapu, Sri Rama Koti

2017-02-10

The most effective vaccine candidate of malaria is based on the Plasmodium falciparum circumsporozoite protein (CSP), a major surface protein implicated in the structural strength, motility, and immune evasion properties of the infective sporozoites. It is suspected that reversible conformational changes of CSP are required for infection of the mammalian host, but the detailed structure and dynamic properties of CSP remain incompletely understood, limiting our understanding of its function in the infection. Here, we report the structural and mechanical properties of the CSP studied using single-molecule force spectroscopy on several constructs, one including the central region of CSP, which is rich in NANP amino acid repeats (CSP rep ), and a second consisting of a near full-length sequence without the signal and anchor hydrophobic domains (CSP ΔHP ). Our results show that the CSP rep is heterogeneous, with 40% of molecules requiring virtually no mechanical force to unfold (<10 piconewtons (pN)), suggesting that these molecules are mechanically compliant and perhaps act as entropic springs, whereas the remaining 60% are partially structured with low mechanical resistance (∼70 pN). CSP ΔHP having multiple force peaks suggests specifically folded domains, with two major populations possibly indicating the open and collapsed forms. Our findings suggest that the overall low mechanical resistance of the repeat region, exposed on the outer surface of the sporozoites, combined with the flexible full-length conformations of CSP, may provide the sporozoites not only with immune evasion properties, but also with lubricating capacity required during its navigation through the mosquito and vertebrate host tissues. We anticipate that these findings would further assist in the design and development of future malarial vaccines. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

The Southern H ii Region Discovery Survey (SHRDS): Pilot Survey

Energy Technology Data Exchange (ETDEWEB)

Brown, C.; Dickey, John M. [School of Physical Sciences, Private Bag 37, University of Tasmania, Hobart, TAS, 7001 (Australia); Jordan, C. [International Centre for Radio Astronomy Research, Curtin University, Perth, WA, 6845 (Australia); Anderson, L. D.; Armentrout, W. P. [Department of Physics and Astronomy, West Virginia University, P.O. Box 6315, Morgantown, WV 26506 (United States); Balser, Dana S.; Wenger, Trey V. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22904 (United States); Bania, T. M. [Institute for Astrophysical Research, Department of Astronomy, Boston University, 725 Commonwealth Avenue, Boston, MA 02215 (United States); Dawson, J. R. [Department of Physics and Astronomy and MQ Research Centre in Astronomy, Astrophysics and Astrophotonics, Macquarie University, NSW, 2109 (Australia); Mc Clure-Griffiths, N. M. [Research School of Astronomy and Astrophysics, The Australian National University, Canberra ACT 2611 (Australia)

2017-07-01

The Southern H ii Region Discovery Survey is a survey of the third and fourth quadrants of the Galactic plane that will detect radio recombination line (RRL) and continuum emission at cm-wavelengths from several hundred H ii region candidates using the Australia Telescope Compact Array. The targets for this survey come from the WISE Catalog of Galactic H ii Regions and were identified based on mid-infrared and radio continuum emission. In this pilot project, two different configurations of the Compact Array Broad Band receiver and spectrometer system were used for short test observations. The pilot surveys detected RRL emission from 36 of 53 H ii region candidates, as well as seven known H ii regions that were included for calibration. These 36 recombination line detections confirm that the candidates are true H ii regions and allow us to estimate their distances.

The Southern H ii Region Discovery Survey (SHRDS): Pilot Survey

International Nuclear Information System (INIS)

Brown, C.; Dickey, John M.; Jordan, C.; Anderson, L. D.; Armentrout, W. P.; Balser, Dana S.; Wenger, Trey V.; Bania, T. M.; Dawson, J. R.; Mc Clure-Griffiths, N. M.

2017-01-01

The Southern H ii Region Discovery Survey is a survey of the third and fourth quadrants of the Galactic plane that will detect radio recombination line (RRL) and continuum emission at cm-wavelengths from several hundred H ii region candidates using the Australia Telescope Compact Array. The targets for this survey come from the WISE Catalog of Galactic H ii Regions and were identified based on mid-infrared and radio continuum emission. In this pilot project, two different configurations of the Compact Array Broad Band receiver and spectrometer system were used for short test observations. The pilot surveys detected RRL emission from 36 of 53 H ii region candidates, as well as seven known H ii regions that were included for calibration. These 36 recombination line detections confirm that the candidates are true H ii regions and allow us to estimate their distances.

PENGARUH LINGKUNGAN KERJA DAN KOMPENSASI KERJA MELALUI MOTIVASI KERJA SEBAGAI VARIABEL INTERVENING TERHADAP KINERJA GURU DI SMA NEGERI 7 SEMARANG PADA TAHUN 2013/2014

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Rahmawati Setia Utami

2014-04-01

Full Text Available Penelitian ini bertujuan untuk mengetahui adanya pengaruh lingkungan kerja dan kompensasi kerja melalui motivasi kerja terhadap kinerja guru di SMA Negeri 7 Semarang pada tahun 2013/2014 secara simultan maupun parsial. Populas penelitian ini adalah seluruh guru di SMA Negeri 7 Semarang, kemudian diambil sampel sejumlah 60 orang guru dengan teknik proposional random sample. Metode pengumpulan data menggunakan dokumentasi dan angket. Metode analisis data menggunakan analisis deskriptif, analisis regresi berganda, dan analisis jalur. Hasil penelitian menunjukan bahwa Hasil uji simultan ( uji F diperoleh F hitung sebesar 5,174 dengan nilai signifikansi 0,003, karena nilai signifikansi jauh lebih kecil dari 0,05 maka Ho ditolak, hal ini menunjukkan bahwa hipotesis yang berbunyi ada pengaruh yang signifikan mengenai lingkungan kerja dan kompensasi kerja melalui motivasi kerja terhadap kinerja guru diterima. Uji parsial ( uji t berdasarkan pengujian diperoleh koefisien untuk variabel lingkungan kerja (X1 diperoleh t hitung = 1,622 dengan signifikansi 0,011 < 0,05, maka Ho ditolak. Hasil pengujian untuk variabel kompensasi kerja (X2 diperoleh t hitung = 2,641 dengan signifikansi 0,021 < 0,005, maka Ho ditolak. Sedangkan untuk variabel motivasi kerja (Y1 diperoleh t hitung = 1,940 dengan signifikansi =0,050. This study aims to investigate the work environment and the work compensation thourgh motivation to the teacher’s performance at SMA Negeri 7 in the academic year 2013/2014 Semarang with work motivation as intervening variabels there any simultaneous and partial. The population in the reasearch is all the teachers at SMA Negeri 7 Semarang amounting to 60 teachers and then samples of the variables use all the teachers with a proportional random sample technique. Methods of data collection using the documentation and questionnaires. Methods of data analysis using descriptive analysis , regression analysis, and path analysis. The results obtained F

[Obesity studies in candidate genes].

Science.gov (United States)

Ochoa, María del Carmen; Martí, Amelia; Martínez, J Alfredo

2004-04-17

There are more than 430 chromosomic regions with gene variants involved in body weight regulation and obesity development. Polymorphisms in genes related to energy expenditure--uncoupling proteins (UCPs), related to adipogenesis and insulin resistance--hormone-sensitive lipase (HLS), peroxisome proliferator-activated receptor gamma (PPAR gamma), beta adrenergic receptors (ADRB2,3), and alfa tumor necrosis factor (TNF-alpha), and related to food intake--ghrelin (GHRL)--appear to be associated with obesity phenotypes. Obesity risk depends on two factors: a) genetic variants in candidate genes, and b) biographical exposure to environmental risk factors. It is necessary to perform new studies, with appropriate control groups and designs, in order to reach relevant conclusions with regard to gene/environmental (diet, lifestyle) interactions.

Epidermal growth factor gene is a newly identified candidate gene for gout

OpenAIRE

Lin Han; Chunwei Cao; Zhaotong Jia; Shiguo Liu; Zhen Liu; Ruosai Xin; Can Wang; Xinde Li; Wei Ren; Xuefeng Wang; Changgui Li

2016-01-01

Chromosome 4q25 has been identified as a genomic region associated with gout. However, the associations of gout with the genes in this region have not yet been confirmed. Here, we performed two-stage analysis to determine whether variations in candidate genes in the 4q25 region are associated with gout in a male Chinese Han population. We first evaluated 96 tag single nucleotide polymorphisms (SNPs) in eight inflammatory/immune pathway- or glucose/lipid metabolism-related genes in the 4q25 re...

EFEKTIVITAS METODE DRILL BERBANTUAN MODUL PEMBELAJARAN DALAM UPAYA MENINGKATKAN HASIL BELAJAR SISWA KOMPETENSI DASAR JURNAL KHUSUS PERUSAHAAN DAGANG PADA SISWA KELAS XII IPS SMA NEGERI 10 SEMARANG TAHUN AJARAN 2013/2014

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Meta Aditya Handayani

2013-11-01

Full Text Available Tujuan penelitian untuk mengetahui penerapan metode drill berbantuan modul dapat meningkatkan hasil belajar akuntansi kompetensi dasar Jurnal Khusus kelas XII IPS SMA Negeri 10 Semarang tahun ajaran 2013/2014 . Penelitian ini menggunakan metode quasi eksperimen. Populasi dalam penelitian ini adalah seluruh kelas XII IPS SMA Negeri 10 Semarang Tahun Ajaran 2013/2014. Metode pengumpulan data yaitu dengan menggunakan tes dan observasi. Pengujian hipotesis menggunakan uji paired sample t-tets dan independent sample t-test. Hasil penelitian menunjukkan peningkatan hasil belajar pada kelas eksperimen dilihat dari 61,16 meningkat mencapai 80,89. Selain itu menunjukkan hasil rata-rata nilai post-test sebesar 80,89 pada kelas eksperimen lebih tinggi dibandingkan nilai post-test sebesar 77,29 pada kelas kontrol. Berdasarkan hasil penelitian dapat disimpulkan bahwa pembelajaran dengan menggunakan metode pembelajaran drill berbantuan modul dapat meningkatkan hasil belajar serta efektif dalam meningkatkan hasil belajar siswa k ompetensi dasar jurnal khusus. Research purposes to determine the application of assisted modules drill method to improve learning outcomes of accounting competence base class XII IPS Special Journal SMA Negeri 10 Semarang school year 2013/2014. This study uses a quasi-experimental methods. The population in this study were all class XII IPS SMA Negeri 10 Semarang Academic Year 2013/2014. Data collection method is by using tests and observation. Hypothesis testing using paired sample t-tets and independent sample t-test. Results showed improved learning outcomes seen in the experimental classes increased to 80.89 from 61.16. In addition it shows the results of the average post-test score of 80.89 in the experimental class higher than the post -test score of 77.29 in the control class. Based on the results of this study concluded that learning by using drill -assisted learning modules to improve learning outcomes and effective in imp

Investigation of candidate regions influencing litter size in Danish Landrace sows

DEFF Research Database (Denmark)

Bjerre, Ditte; Mark, Thomas; Sørensen, P.

2010-01-01

allele effect of microsatellite alleles in the region. In spite of the apparent increased historical selection pressure on chromosome 13, fairly large variation in allele effects was observed, indicating that the markers within the region may be used for marker-assisted selection. However, substantial...... and low EBV for litter size were genotyped. An assignment test showed that 91 and 90% of the sows could be assigned correctly to the group of sows representing high and low EBV, respectively, based on genotype information. Allele effects were estimated separately for each marker by using deregressed EBV...... and a linear model that include both a polygenic and an allele effect. The investigated region on chromosome 13 was found to have a greater average identity by state relationship compared with the other regions, indicating that selection has taken place in this region. This is supported by an increased average...

Optimized candidal biofilm microtiter assay

NARCIS (Netherlands)

Krom, Bastiaan P.; Cohen, Jesse B.; Feser, Gail E. McElhaney; Cihlar, Ronald L.

Microtiter based candidal biofilm formation is commonly being used. Here we describe the analysis of factors influencing the development of candidal biofilms such as the coating with serum, growth medium and pH. The data reported here show that optimal candidal biofilm formation is obtained when

Regional frontal gray matter volume associated with executive function capacity as a risk factor for vehicle crashes in normal aging adults.

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Hiroyuki Sakai

Full Text Available Although low executive functioning is a risk factor for vehicle crashes among elderly drivers, the neural basis of individual differences in this cognitive ability remains largely unknown. Here we aimed to examine regional frontal gray matter volume associated with executive functioning in normal aging individuals, using voxel-based morphometry (VBM. To this end, 39 community-dwelling elderly volunteers who drove a car on a daily basis participated in structural magnetic resonance imaging, and completed two questionnaires concerning executive functioning and risky driving tendencies in daily living. Consequently, we found that participants with low executive function capacity were prone to risky driving. Furthermore, VBM analysis revealed that lower executive function capacity was associated with smaller gray matter volume in the supplementary motor area (SMA. Thus, the current data suggest that SMA volume is a reliable predictor of individual differences in executive function capacity as a risk factor for vehicle crashes among elderly persons. The implication of our results is that regional frontal gray matter volume might underlie the variation in driving tendencies among elderly drivers. Therefore, detailed driving behavior assessments might be able to detect early neurodegenerative changes in the frontal lobe in normal aging adults.

Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

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Hinds David A

2004-11-01

Full Text Available Abstract Association studies are used to identify genetic determinants of complex human traits of medical interest. With the large number of validated single nucleotide polymorphisms (SNPs currently available, two limiting factors in association studies are genotyping capability and costs. Pooled DNA genotyping has been proposed as an efficient means of screening SNPs for allele frequency differences in case-control studies and for prioritising them for subsequent individual genotyping analysis. Here, we apply quantitative pooled genotyping followed by individual genotyping and replication to identify associations with human serum high-density lipoprotein (HDL cholesterol levels. The DNA from individuals with low and high HDL cholesterol levels was pooled separately, each pool was amplified by polymerase chain reaction in triplicate and each amplified product was separately hybridised to a high-density oligonucleotide array. Allele frequency differences between case and control groups with low and high HDL cholesterol levels were estimated for 7,283 SNPs distributed across 71 candidate gene regions spanning a total of 17.1 megabases. A novel method was developed to take advantage of independently derived haplotype map information to improve the pooled estimates of allele frequency differences. A subset of SNPs with the largest estimated allele frequency differences between low and high HDL cholesterol groups was chosen for individual genotyping in the study population, as well as in a separate replication population. Four SNPs in a single haplotype block within the cholesteryl ester transfer protein (CETP gene interval were significantly associated with HDL cholesterol levels in both populations. Our study is among the first to demonstrate the application of pooled genotyping followed by confirmation with individual genotyping to identify genetic determinants of a complex trait.

Storm intensity and old-growth forest disturbances in the Amazon region

Science.gov (United States)

F.D.B. Espírito-Santo; M. Keller; B. Braswell; B.W. Nelson; S. Frolking; G. Vicente

2010-01-01

We analyzed the pattern of large forest disturbances or blow‐downs apparently caused by severe storms in a mostly unmanaged portion of the Brazilian Amazon using 27 Landsat images and daily precipitation estimates from NOAA satellite data. For each Landsat a spectral mixture analysis (SMA) was applied. Based on SMA, we detected and mapped 279 patches (from 5 ha to 2,...

Improved selection criteria for H II regions, based on IRAS sources

Science.gov (United States)

Yan, Qing-Zeng; Xu, Ye; Walsh, A. J.; Macquart, J. P.; MacLeod, G. C.; Zhang, Bo; Hancock, P. J.; Chen, Xi; Tang, Zheng-Hong

2018-05-01

We present new criteria for selecting H II regions from the Infrared Astronomical Satellite (IRAS) Point Source Catalogue (PSC), based on an H II region catalogue derived manually from the all-sky Wide-field Infrared Survey Explorer (WISE). The criteria are used to augment the number of H II region candidates in the Milky Way. The criteria are defined by the linear decision boundary of two samples: IRAS point sources associated with known H II regions, which serve as the H II region sample, and IRAS point sources at high Galactic latitudes, which serve as the non-H II region sample. A machine learning classifier, specifically a support vector machine, is used to determine the decision boundary. We investigate all combinations of four IRAS bands and suggest that the optimal criterion is log(F_{60}/F_{12})≥ ( -0.19 × log(F_{100}/F_{25})+ 1.52), with detections at 60 and 100 {μ}m. This selects 3041 H II region candidates from the IRAS PSC. We find that IRAS H II region candidates show evidence of evolution on the two-colour diagram. Merging the WISE H II catalogue with IRAS H II region candidates, we estimate a lower limit of approximately 10 200 for the number of H II regions in the Milky Way.

Pengaruh Layanan Penguasaan Konten Teknik Sosiodrama Terhadap Perilaku Asertif Siswa dengan Guru SMA Negeri 3 Magelang Tahun Ajaran 2015/2016

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Aji Taufiq Pambudi

2017-03-01

Full Text Available This study was conducted based on the phenomenon in SMA 3 Magelang which indicate that there are students who have a low assertive behavior. The research was conducted on July 28 to September 2, 2015. This study aims to determine students' assertive behavior before and after the service, and to know the influence of the control service content sociodramas techniques in improving assertive behavior class XI MIA 1. The type of research is experimental research. Methods of data collection using the instrument scale psychological scale assertive capability. Methods of data analysis using descriptive percentages and t-test. The results showed that the percentage of early before getting services at 55.99% and after getting treatment showed a percentage of 83.54% is thus increased by 27.55%. Results of t-test showed that the values ​​obtained tcalculated = 17.00> ttable = 2.00 at the 5% significance level, the calculation of the t-test showed that tcalculated> t ttable, so that Ho refused and Ha accepted. Based on the results of this study concluded that the assertive behavior class XI MIA 1 at SMA 3 Magelang before getting services with lower category, after getting the service with high category, so that assertive behavior through mastery of content services sociodrama technique can be improved.

KEADILAN ORGANISASIONAL DAN KONSEKUENSINYA TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR GURU SMA DAN SMK KOTA MADIUN*

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Veronika Agustini Srimulyani

2017-11-01

Full Text Available Keadilan organisasional memiliki potensi untuk menciptakan manfaat besar bagi organisasi dan karyawan, dan salah satu manfaatnya adalah menumbuhkan extra-role behavior (ERB atau organizational citizenship behavior (OCB. Tujuan dari penelitian ini untuk menganalisis konsekuensi keadilan organisasional (keadilan distributif, keadilan prosedural, dan keadilan interaksional pada organizational citizenship behavior guru SMA dan guru SMK di Kota Madiun. OCB dibagi menjadi dua jenis yaitu citizenship behaviors directed toward individuals (OCB-I dan citizenship behaviors directed towards the organisation (OCB-O. Penelitian ini menggunakan pendekatan kuantitatif dengan metode survei. Sampel penelitian ini adalah 409 guru, yang dipilih secara non-acak. Data diperoleh dengan menyebarkan kuesioner. Analisis data menggunakan analisis regresi. Hasil penelitian disimpulkan: keadilan distributif dan keadilan interaksional berpengaruh positif signifikan terhadap OCB-I dan OCB-O; keadilan prosedural tidak berpengaruh signifikan terhadap OCB-I tetapi keadilan prosedural berpengaruh positif signifikan terhadap OCB-O.

PENINGKATAN KEMAMPUAN BERPIKIR KRITIS DAN KETERAMPILAN PROSES SAINS SISWA SMA MELALUI IMPLEMENTASI PROBLEM BASED LEARNING DIPADU THINK PAIR SHARE

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Abu Husen

2017-06-01

Full Text Available This study aims to implement of Problem Based Learning combined Think Pair Share in order to improve critical thinking and science process skills of students at XI IPA SMA. This research was classroom action research. The subjects were 28 students of classroom XI IPA 1 SMAN 1 Kasiman Bojonegoro 2016/2017. This research was conducted in two cycles. The research data consists of the learning realized by observation, the results of the critical thinking paper and pencil tests, and the science process skills by observation. Data were analyzed by descriptive qualitative technique. The results showed that the combined PBL and TPS learning model can improve the ability of critical thinking, and science process skills students of classroom XI IPA 1 SMAN 1 Kasiman Bojonegoro. Penelitian ini bertujuan untuk menerapkan Problem Based Learning dipadu Think Pair Share dalam rangka meningkatkan kemampuan berpikir kritis dan keterampilan proses sains siswa kelas XI IPA SMA. Penelitian ini merupakan penelitian tindakan kelas. Subjek penelitian adalah siswa kelas XI IPA 1 SMAN 1 Kasiman Bojonegoro tahun pelajaran 2016/2017 dengan jumlah 28 siswa. Penelitian dilaksanakan selama dua siklus. Data penelitian terdiri atas hasil observasi keterlaksanaan pembelajaran, hasil tes tulis kemampuan berpikir kritis, dan hasil observasi keterampilan proses sains. Data dianalisis secara deskriptif kualitatif. Hasil penelitian menunjukkan bahwa model pembelajaran PBL dipadu TPS dapat meningkatkan kemampuan berpikir kritis dan keterampilan proses sains siswa kelas XI IPA 1 SMAN 1 Kasiman Bojonegoro.

Issue-Advocacy versus Candidate Advertising: Effects on Candidate Preferences and Democratic Process.

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Pfau, Michael; Holbert, R. Lance; Szabo, Erin Alison; Kaminski, Kelly

2002-01-01

Examines the influence of soft-money-sponsored issue-advocacy advertising in U.S. House and Senate campaigns, comparing its effects against candidate-sponsored positive advertising and contrast advertising on viewers' candidate preferences and on their attitude that reflect democratic values. Reveals no main effects for advertising approach on…

Next-generation sequencing to identify candidate genes and develop diagnostic markers for a novel Phytophthora resistance gene, RpsHC18, in soybean.

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Zhong, Chao; Sun, Suli; Li, Yinping; Duan, Canxing; Zhu, Zhendong

2018-03-01

A novel Phytophthora sojae resistance gene RpsHC18 was identified and finely mapped on soybean chromosome 3. Two NBS-LRR candidate genes were identified and two diagnostic markers of RpsHC18 were developed. Phytophthora root rot caused by Phytophthora sojae is a destructive disease of soybean. The most effective disease-control strategy is to deploy resistant cultivars carrying Phytophthora-resistant Rps genes. The soybean cultivar Huachun 18 has a broad and distinct resistance spectrum to 12 P. sojae isolates. Quantitative trait loci sequencing (QTL-seq), based on the whole-genome resequencing (WGRS) of two extreme resistant and susceptible phenotype bulks from an F 2:3 population, was performed, and one 767-kb genomic region with ΔSNP-index ≥ 0.9 on chromosome 3 was identified as the RpsHC18 candidate region in Huachun 18. The candidate region was reduced to a 146-kb region by fine mapping. Nonsynonymous SNP and haplotype analyses were carried out in the 146-kb region among ten soybean genotypes using WGRS. Four specific nonsynonymous SNPs were identified in two nucleotide-binding sites-leucine-rich repeat (NBS-LRR) genes, RpsHC18-NBL1 and RpsHC18-NBL2, which were considered to be the candidate genes. Finally, one specific SNP marker in each candidate gene was successfully developed using a tetra-primer ARMS-PCR assay, and the two markers were verified to be specific for RpsHC18 and to effectively distinguish other known Rps genes. In this study, we applied an integrated genomic-based strategy combining WGRS with traditional genetic mapping to identify RpsHC18 candidate genes and develop diagnostic markers. These results suggest that next-generation sequencing is a precise, rapid and cost-effective way to identify candidate genes and develop diagnostic markers, and it can accelerate Rps gene cloning and marker-assisted selection for breeding of P. sojae-resistant soybean cultivars.

SMA and CARMA observations of young brown dwarfs in ρ Ophiuchi and Taurus

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Lee C.-F.

2011-07-01

Full Text Available Molecular outflows provide vital information about the earliest stages in the birth of stars, studying the molecular outflow properties is therefore crucial for understanding how stars form. Brown dwarfs with masses between that of stars and planets are not massive enough to maintain stable hydrogen-burning fusion reactions during most of their lifetime. Their origins are subject to much debate in recent literature because their masses are far below the typical mass where core collapse is expected to occur. Based on Submillimeter Array (SMA and Combined Array for Research in Millimeter-wave Astronomy (CARMA observations, we present the first detections of bipolar molecular outflows from young brown dwarfs in ρ Ophiuchi and Taurus. Our results demonstrate that the bipolar molecular outflow operates down to brown dwarf masses, occurring in brown dwarfs as a scaled-down version of the universal process seen in young low-mass stars. This demonstrates that brown dwarfs and low-mass stars likely share the same formation mechanism.

The Southern HII Region Discovery Survey

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Wenger, Trey; Miller Dickey, John; Jordan, Christopher; Bania, Thomas M.; Balser, Dana S.; Dawson, Joanne; Anderson, Loren D.; Armentrout, William P.; McClure-Griffiths, Naomi

2016-01-01

HII regions are zones of ionized gas surrounding recently formed high-mass (OB-type) stars. They are among the brightest objects in the sky at radio wavelengths. HII regions provide a useful tool in constraining the Galactic morphological structure, chemical structure, and star formation rate. We describe the Southern HII Region Discovery Survey (SHRDS), an Australia Telescope Compact Array (ATCA) survey that discovered ~80 new HII regions (so far) in the Galactic longitude range 230 degrees to 360 degrees. This project is an extension of the Green Bank Telescope HII Region Discovery Survey (GBT HRDS), Arecibo HRDS, and GBT Widefield Infrared Survey Explorer (WISE) HRDS, which together discovered ~800 new HII regions in the Galactic longitude range -20 degrees to 270 degrees. Similar to those surveys, candidate HII regions were chosen from 20 micron emission (from WISE) coincident with 10 micron (WISE) and 20 cm (SGPS) emission. By using the ATCA to detect radio continuum and radio recombination line emission from a subset of these candidates, we have added to the population of known Galactic HII regions.

Hereditary motor and autonomic neuronopathy 1 maps to chromosome 20q13.2-13.3

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W. Marques Jr.

2004-11-01

Full Text Available The spinal muscular atrophies (SMA or hereditary motor neuronopathies result from the continuous degeneration and death of spinal cord lower motor neurons, leading to progressive muscular weakness and atrophy. We describe a large Brazilian family exhibiting an extremely rare, late-onset, dominant, proximal, and progressive SMA accompanied by very unusual manifestations, such as an abnormal sweating pattern, and gastrointestinal and sexual dysfunctions, suggesting concomitant involvement of the autonomic nervous system. We propose a new disease category for this disorder, `hereditary motor and autonomic neuronopathy', and attribute the term, `survival of motor and autonomic neurons 1' (SMAN1 to the respective locus that was mapped to a 14.5 cM region on chromosome 20q13.2-13.3 by genetic linkage analysis and haplotype studies using microsatellite polymorphic markers. This locus lies between markers D20S120 and D20S173 showing a maximum LOD score of 4.6 at D20S171, defining a region with 33 known genes, including several potential candidates. Identifying the SMAN1 gene should not only improve our understanding of the molecular mechanisms underlying lower motor neuron diseases but also help to clarify the relationship between motor and autonomic neurons.

Quantitative expression profile of distinct functional regions in the adult mouse brain.

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Takeya Kasukawa

Full Text Available The adult mammalian brain is composed of distinct regions with specialized roles including regulation of circadian clocks, feeding, sleep/awake, and seasonal rhythms. To find quantitative differences of expression among such various brain regions, we conducted the BrainStars (B* project, in which we profiled the genome-wide expression of ∼50 small brain regions, including sensory centers, and centers for motion, time, memory, fear, and feeding. To avoid confounds from temporal differences in gene expression, we sampled each region every 4 hours for 24 hours, and pooled the samples for DNA-microarray assays. Therefore, we focused on spatial differences in gene expression. We used informatics to identify candidate genes with expression changes showing high or low expression in specific regions. We also identified candidate genes with stable expression across brain regions that can be used as new internal control genes, and ligand-receptor interactions of neurohormones and neurotransmitters. Through these analyses, we found 8,159 multi-state genes, 2,212 regional marker gene candidates for 44 small brain regions, 915 internal control gene candidates, and 23,864 inferred ligand-receptor interactions. We also found that these sets include well-known genes as well as novel candidate genes that might be related to specific functions in brain regions. We used our findings to develop an integrated database (http://brainstars.org/ for exploring genome-wide expression in the adult mouse brain, and have made this database openly accessible. These new resources will help accelerate the functional analysis of the mammalian brain and the elucidation of its regulatory network systems.

Regional contributions to particulate matter concentration in the Seoul metropolitan area, South Korea: seasonal variation and sensitivity to meteorology and emissions inventory

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Kim, Hyun Cheol; Kim, Eunhye; Bae, Changhan; Cho, Jeong Hoon; Kim, Byeong-Uk; Kim, Soontae

2017-09-01

The impact of regional emissions (e.g., domestic and international) on surface particulate matter (PM) concentrations in the Seoul metropolitan area (SMA), South Korea, and its sensitivities to meteorology and emissions inventories are quantitatively estimated for 2014 using regional air quality modeling systems. Located on the downwind side of strong sources of anthropogenic emissions, South Korea bears the full impact of the regional transport of pollutants and their precursors. However, the impact of foreign emissions sources has not yet been fully documented. We utilized two regional air quality simulation systems: (1) a Weather Research and Forecasting and Community Multi-Scale Air Quality (CMAQ) system and (2) a United Kingdom Met Office Unified Model and CMAQ system. The following combinations of emissions inventories are used: the Intercontinental Chemical Transport Experiment-Phase B, the Inter-comparison Study for Asia 2010, and the National Institute of Environment Research Clean Air Policy Support System. Partial contributions of domestic and foreign emissions are estimated using a brute force approach, adjusting South Korean emissions to 50 %. Results show that foreign emissions contributed ˜ 60 % of SMA surface PM concentration in 2014. Estimated contributions display clear seasonal variation, with foreign emissions having a higher impact during the cold season (fall to spring), reaching ˜ 70 % in March, and making lower contributions in the summer, ˜ 45 % in September. We also found that simulated surface PM concentration is sensitive to meteorology, but estimated contributions are mostly consistent. Regional contributions are also found to be sensitive to the choice of emissions inventories.

PENINGKATAN AKTIVITAS DAN HASIL BELAJAR SISWA PADA KOMPETENSI DASAR MENJELASKAN MANFAAT PERHITUNGAN PENDAPATAN NASIONAL DENGAN MODEL PEMBELAJARAN DRILL AND PRACTICE KELAS X SMA N 1 BAWANG

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Ristia Arif

2015-06-01

Full Text Available Permasalahan yang dikaji dalam penelitian ini adalah apakah penerapan model pembelajaran drill (latihan and practice pada standar kompetensi menjelaskan manfaat perhitungan pendapatan nasional pada siswa kelas X SMA 1 Bawang dapat meningkatkan aktivitas belajar dan hasil belajar siswa ? Subyek penelitian ini adalah siswa kelas X.F SMA 1 Bawang yang berjumlah 27 orang. Penelitian ini menggunakan Penelitian Tindakan Kelas yang terdiri dari dua siklus. Tiap siklusnya merupakan rangkaian kegiatan yang terdiri dari 1 perencanaan untuk membuat instrumen penelitian lainnya, 2 Pelaksanaan, melaksanakan pembelajaran kearsipan pokok sistem kartu kendali, 3 Observasi / pengamatan, 4 refleksi, menganalisis data hasil pengamatan. Hasil penelitian menunjukkan bahwa dengan menerapkan model drill (latihan and practice hasil belajar siswa mengalami peningkatan pada masing-masing siklus, hal ini terlihat dari adanya peningkatan pada masing-masing siklus yaitu hasil tes siklus I nilai rata-rata 72 dan siklus II rata-rata 78.Dari lembar observasi siswa dari siklus I aktivitas siswa sebanyak 64,28% dan pada siklus II meningkat menjadi 92,85%.Hasil pengamatan pada guru siklus I sebesar 72,5% dan pada siklus II sebesar 92,5%. The problems examined in this study is whether the application of learning models drill and practice the standard of competence to explain the benefits of the national income accounts in class X SMA 1 Bawang can enhance learning activities and student learning outcomes? The subjects of this study were high school students XF SMA 1 Bawang, amounting to 27 people. This study uses a Class Action Research consisting of two cycles. Each cycle is a series of activities consisting of 1 planning to make other research instruments, 2 Implementation, implementing learning basic filing system controller card, 3 Observation / observation, 4 reflection, analyzing the observed data. The results show that by applying the model drill and practice learning

Faktor – Faktor Penyebab Prokrastinasi Akademik pada Siswa Kelas XI SMA Negeri Kabupaten Temanggung

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Ujang Candra

2014-10-01

Full Text Available Prokrastinasi akademik adalah jenis penundaan yang dilakukan pada jenis tugas formal yang berhubungan dengan tugas akademik. Salah satunya yang sering menjadi prokrastinator adalah siswa. Jika prokrastinasi ini tidak segera dibenahi, akan merugikan siswa itu sendiri. Perkembangan siswa dalam meraih prestasi akademik menjadi terganggu. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor penyebab prokrastinasi akademik pada siswa kelas XI SMA Negeri Kabupaten Temanggung. Angket diberikan kepada 221 siswa SMA Negeri Kabupaten Temanggung, serta 6 orang responden untuk diwawancara. Analisis data menggunakan analisis kuantitatif yang mencakup deskriptif presentase, dan analisis kulitatif hasil wawancara. Hasil penelitian menemukan bahwa faktor internal penyebab prokrastinasi akademik dilihat dari kondisi fisik (69%, kondisi psikologis (73%. Kemudian faktor eksternal penyebab prokrastinasi akademik dilihat dari kondisi keluarga (75%, lingkungan sekolah (67%, lingkungan masyarakat (66%. Simpulan penelitian ini bahwa faktor internal utama penyebab prokrastinasi akademik pada siswa adalah kondisi fisik dan faktor eksternal yang paling utama penyebab prokrastinasi akademik pada siswa adalah lingkungan sekolah. Bagi konselor sekolah, dapat memberikan layanan prnguasaan konten mengenai manajemen waktu sebagai upaya mencegah munculnya perilaku prokrastinasi akademik. Academic procrastination is the kind of delay that made the tasks associated with the assignment of formal academic. One of them is that often a student prokrastinator. If procrastination is not immediately addressed, it would be detrimental to the students themselves. The development of students academic achievement become impaired. The purpose of this study is to determine the internal factors and external factors that cause students academic procrastination.. Questionnaire given to 221 students of High School in Temanggung, and 6 respondents to be interviewed. Data analysis using

IMPROVING LEARNING PROCESS AND STUDENT RESULTS LEARNING TO TUNE-UPMOTORCYCLE USING DEMONSTRATION METHODOF CLASS XI SMA N 1 PLAYEN YEAR STUDY2013/2014

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Haryono Haryono

2014-12-01

Full Text Available This research is to improve the learning process and results in learning a tune-up motorcycle  using the demonstrationmethod of class XI SMA 1 Playen.              This research is a classroom action research (PTK, using the demonstration method.Subyek this study were students of class XI SMA Negeri 1 Playen.Theimplementationofthisstudyusing3cycles,there is a (planning, implementation (actuating, observation (observing, and reflection (reflecting. Collecting data in this study are observations of student learning process and student learning outcomes test data pre-test, postesI, II, III and documentation as a support to the two data. Further observation data based on the observation of student learning just learning the positive process of learning student and test data were analyzed for comparison. Indicators of success in this classroom action research that student learning increases towards positive along with the use of methods of demonstration, is to see an increase from the pre-cycle to end the first cycle, the first cycle to the second cycle and the secondcyclebycycle III.             From the results of this study concluded that the method could improve the demonstration of positive student learning, from the first cycle of 30%, 50% second cycle and third cycle of 80%. Learning is also more effective with students indicated more quickly adapt as a positive activity, especially in terms of increased student asked, noting the test and work on the problems. Demonstration method can improve the learning outcomes  students of class XI SMA 1 Playen as evidenced by an increase in the average yield final test first cycle of 64.09; second cycle of 77.82 and 78.86 for the third cycle. So it proved with the increasing positive student learning canalso improve student learning outcomes.

KEBIJAKAN KEPALA SEKOLAH TERHADAP PELAYANAN BIMBINGAN KONSELING DI SMA NEGERI SE-KABUPATEN PURBALINGGA

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Dinka Rizki Apriliana Mahanggi

2014-06-01

Full Text Available Tujuan penelitian ini untuk mengetahui bagaimana pelaksanaan kebijakan kepala sekolah terhadap pelayanan BK di SMA Negeri se-Kabupaten Purbalingga. Penelitian ini adalah penelitian kualitatifdengan pendekatan penelitian kebijakan, sumber dataprimer dan sekunder. Subyek penelitian yaitu seluruh kepala SMA Negeri se-Kabupaten Purbalingga. Instrumen yang digunakan adalah observasi, wawancara dan dokumentasi.Hasil penelitian menunjukkan bahwa kebijakan sarpras untuk BK sudah cukup lengkap walaupun belum maksimal karena minimnya anggaran dana. Kebijakan alokasi jam BK, prosentasenya 20% sama sekali tidak ada jam BK, 40% semua kelas ada jam BK, sedangkan 40% lainnya hanya sebagian kelas yang ada. Kebijakan mengenai kualifikasi akademik konselor, 50% dari jumlah seluruh guru BK yang berlatarbelakang pendidikan BK, dan 50% lainnya non BK. Hampir semua guru BK sudah memenuhi kriteria beban kerja guru BK yaitu minimal mengampu 150 siswa.Supervisi BK oleh kepala sekolah masih belum optimal. Anggapan BK sebagai polisi sekolah sudah mulai hilang karena kebijakan kepala sekolah yang menetapkan guru BK tidak boleh menghukum siswa. Simpulan penelitiannya yaitu secara umum kepala sekolah sudah mengetahui peran serta tanggungjawab kepala sekolah terhadap pelayanan BK, tetapi dalam pelaksanaannya kepala sekolah kurang menerapkan pemahamannya serta kurang melihat kebutuhan dari guru BK dan siswa. The purpose of this study is to find out how the application of headmaster’ policytowards guidance and counseling service in state high schools. It used qualitative research with policy research analysis approach, primary and secondary data sources. The subjects of this research are all headmasters of state high schools throughout Purbalingga district. Observation, interview, documentation are the instruments used in this research. Result of this study shows that in providing the infrastructureis generally appropriate. There are 20% of which haven’t any time allocation

Kebijakan Kepala Sekolah Terhadap Pelayanan Bimbingan Konseling di SMA Negeri Se-Kabupaten Purbalingga

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Dinka Rizki Apriliana Mahanggi

2014-06-01

Full Text Available Tujuan penelitian ini untuk mengetahui bagaimana pelaksanaan kebijakan kepala sekolah terhadap pelayanan BK di SMA Negeri se-Kabupaten Purbalingga. Penelitian ini adalah penelitian kualitatifdengan pendekatan penelitian kebijakan, sumber dataprimer dan sekunder. Subyek penelitian yaitu seluruh kepala SMA Negeri se-Kabupaten Purbalingga. Instrumen yang digunakan adalah observasi, wawancara dan dokumentasi.Hasil penelitian menunjukkan bahwa kebijakan sarpras untuk BK sudah cukup lengkap walaupun belum maksimal karena minimnya anggaran dana. Kebijakan alokasi jam BK, prosentasenya 20% sama sekali tidak ada jam BK, 40% semua kelas ada jam BK, sedangkan 40% lainnya hanya sebagian kelas yang ada. Kebijakan mengenai kualifikasi akademik konselor, 50% dari jumlah seluruh guru BK yang berlatarbelakang pendidikan BK, dan 50% lainnya non BK. Hampir semua guru BK sudah memenuhi kriteria beban kerja guru BK yaitu minimal mengampu 150 siswa.Supervisi BK oleh kepala sekolah masih belum optimal. Anggapan BK sebagai polisi sekolah sudah mulai hilang karena kebijakan kepala sekolah yang menetapkan guru BK tidak boleh menghukum siswa. Simpulan penelitiannya yaitu secara umum kepala sekolah sudah mengetahui peran serta tanggungjawab kepala sekolah terhadap pelayanan BK, tetapi dalam pelaksanaannya kepala sekolah kurang menerapkan pemahamannya serta kurang melihat kebutuhan dari guru BK dan siswa. The purpose of this study is to find out how the application of headmaster’ policytowards guidance and counseling service in state high schools. It used qualitative research with policy research analysis approach, primary and secondary data sources. The subjects of this research are all headmasters of state high schools throughout Purbalingga district. Observation, interview, documentation are the instruments used in this research. Result of this study shows that in providing the infrastructureis generally appropriate. There are 20% of which haven’t any time allocation

BEEF CATTLE MUSCULARITY CANDIDATE GENES

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Irida Novianti

2010-04-01

Full Text Available Muscularity is a potential indicator for the selection of more productive cattle. Mapping quantitative trait loci (QTL for traits related to muscularity is useful to identify the genomic regions where the genes affecting muscularity reside. QTL analysis from a Limousin-Jersey double backcross herd was conducted using QTL Express software with cohort and breed as the fixed effects. Nine QTL suggested to have an association with muscularity were identified on cattle chromosomes BTA 1, 2, 3, 4, 5, 8, 12, 14 and 17. The myostatin gene is located at the centromeric end of chromosome 2 and not surprisingly, the Limousin myostatin F94L variant accounted for the QTL on BTA2. However, when the myostatin F94L genotype was included as an additional fixed effect, the QTL on BTA17 was also no longer significant. This result suggests that there may be gene(s that have epistatic effects with myostatin located on cattle chromosome 17. Based on the position of the QTL in base pairs, all the genes that reside in the region were determined using the Ensembl data base (www.ensembl.org. There were two potential candidate genes residing within these QTL regions were selected. They were Smad nuclear interacting protein 1 (SNIP1 and similar to follistatin-like 5 (FSTL5. (JIIPB 2010 Vol 20 No 1: 1-10

Identification of Candidate Genes Responsible for Stem Pith Production Using Expression Analysis in Solid-Stemmed Wheat.

Science.gov (United States)

Oiestad, A J; Martin, J M; Cook, J; Varella, A C; Giroux, M J

2017-07-01

The wheat stem sawfly (WSS) is an economically important pest of wheat in the Northern Great Plains. The primary means of WSS control is resistance associated with the single quantitative trait locus (QTL) , which controls most stem solidness variation. The goal of this study was to identify stem solidness candidate genes via RNA-seq. This study made use of 28 single nucleotide polymorphism (SNP) makers derived from expressed sequence tags (ESTs) linked to contained within a 5.13 cM region. Allele specific expression of EST markers was examined in stem tissue for solid and hollow-stemmed pairs of two spring wheat near isogenic lines (NILs) differing for the QTL. Of the 28 ESTs, 13 were located within annotated genes and 10 had detectable stem expression. Annotated genes corresponding to four of the ESTs were differentially expressed between solid and hollow-stemmed NILs and represent possible stem solidness gene candidates. Further examination of the 5.13 cM region containing the 28 EST markers identified 260 annotated genes. Twenty of the 260 linked genes were up-regulated in hollow NIL stems, while only seven genes were up-regulated in solid NIL stems. An -methyltransferase within the region of interest was identified as a candidate based on differential expression between solid and hollow-stemmed NILs and putative function. Further study of these candidate genes may lead to the identification of the gene(s) controlling stem solidness and an increased ability to select for wheat stem solidness and manage WSS. Copyright © 2017 Crop Science Society of America.

THE RELEVANCY OF ENGLISH IN CONTEXT FOR SMA/MA STUDENT YEAR ONE TEXTBOOK TO THE CURRICULUM USED

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Qudwatin Nisak

2013-11-01

Full Text Available To improve the quality of English education in Nanggroe Aceh Darussalam (NAD, the Department of Education of NAD as policymaker has made some efforts, among others, sending some teachers for overseas training and also conducting in-service training in designing English teaching material. One of the results of the projects done by the Department of Education of NAD is an English textbook entitled “English in Context for SMA/MA student year 1”, was distributed to some senior high schools in Banda Aceh in 2005. Lately, the textbook hasn’t been used effectively. Based on that fact, it is considered necessary to evaluate the textbook in order to know its relevant to curriculum used. The data of this study are the contents of English in Context for SMA/MA students year 1, consist of objectives of the textbook, themes chosen, skills presented, task designed, types of the text, language focus provided, vocabulary, and just for fun sections as well as the physical condition of textbook. After the data were put based on their classifications, they were analyzed qualitatively by finding its relevancy to CBC. The relevant elements of textbook to CBC and the deficient element of the textbook were explained descriptively. The result shows that only small portions of suggested material in CBC are provided in the textbook. The types of listening texts which are relevant to CBC are only recount and report. The genre of the reading texts which are relevant to CBC are recount, report, and news items. Meanwhile, the speaking task types provided in the textbook are dialogue, talks/speeches, plays/role play, discussion, and report. The deficient elements found in the textbook are lack of clarity of the authors’ objective, repetition of the tasks designed, lack of variation in some skill’s presentation and some irrelevant materials to CBC.

Analysis of a positional candidate gene for inflammatory bowel disease: NRAMP2

NARCIS (Netherlands)

Stokkers, P. C.; Huibregtse, K.; Leegwater, A. C.; Reitsma, P. H.; Tytgat, G. N.; van Deventer, S. J.

2000-01-01

Genome scans have identified a region spanning 40 cM on the long arm of chromosome 12 as a susceptibility locus for inflammatory bowel disease (IBD). This locus contains several candidate genes for IBD, one of which is the gene for the natural resistance associated macrophage protein 2 (NRAMP2).

Profil Antisipasi Siswa SMA Dalam Memecahkan Masalah Integral

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Erfan Yudianto

2015-06-01

Full Text Available Penelitian ini dilatarbelakangi oleh sulitnya siswa dalam menyelesaikan masalah integral khusunya luas daerah. Banyak siswa hanya menyelesaikan masalah integral hanya berdasarkan rumus yang sudah disediakan. Siswa jarang mengaitkan konsep-konsep yang saling terkait, dalam hal ini konsep integral subpokokbahasan luas daerah.Tujuan penelitian ini untuk mendeskripsikan Profil antisipasi siswa SMA dalam memecahkan masalah integral. Hasil penelitian ini dapat dimanfaatkan oleh guru untuk membantu siswa mengaitkan konsep-konsep yang belum terkait.  Penelitian ini menggunakan metode tes dan wawancara. Tes berupa  tes kemampuan matematika yang diberikan kepada siswa, sehingga diperoleh siswa berkemampuan tinggi dan wawancara diberikan kepada siswa yang bersangkutan untuk menggali dan melihat jaringan konsep yang dimiliki siswa dalam menyelesaikan masalah integral. Subjek dalam penelitian ini termasuk dalam antisipasi terinternasilsasi dikarenakan siswa secara spontan menerapkan rumus integral tanpa menganalisis soal yang diberikan.This research is motivated by the difficulty of students in solving integral problems especially the area. Many students just completed the integral problems just based on a formula that has been provided. Students rarely associate the concepts are interrelated, in this case the integral concept of the area. The purpose of this study was to describe the profile anticipation of high school students in problem solving integrals. The results could be used by teachers to help students link the concepts are not related. This study uses tests and interviews. The tests such as math skills test given to students, in order to obtain a high ability students and interviews given to the student to explore and see the network concept of the students in problem solving integrals. Subjects in this study are included in anticipation terinternasilsasi because students spontaneously apply the integral formula without analyzing the questions

A Complete Census of the ~7000 Milky Way HII Regions

Science.gov (United States)

Armentrout, William Paul; Anderson, Loren Dean; Wenger, Trey; Bania, Thomas; Balser, Dana; Dame, Thomas; Dickey, John M.; Dawson, Joanne; Jordan, Christopher H.; McClure-Griffiths, Naomi M.; Andersen, Morten

2018-01-01

HII regions are the archetypical tracers of high-mass star formation. Because of their high luminosities, they can be seen across the entire Galactic disk from mid-infrared to radio wavelengths. A uniformly sensitive survey of Galactic HII regions would allow us to constrain the properties of Galactic structure and star formation. We have cataloged over 8000 HII regions and candidates in the WISE Catalog of Galactic HII Regions (astro.phys.wvu.edu/wise), but only 2000 of these are confirmed HII regions to date.To bring us closer to a complete census of high-mass star formation regions in the Milky Way, we have several ongoing observational campaigns. These efforts include (1) Green Bank Telescope radio recombination line (RRL) observations as part of the HII Region Discovery Survey (HRDS); (2) Australia Telescope Compact Array observations of southern HII region candidates in the Southern HII Region Discovery Survey (SHRDS); (3) Green Bank and Gemini North Telescope observations of star formation regions thought to reside at the edge of the star forming disk in the Outer Scutum-Centaurus Arm (OSC); and (4) Very Large Array continuum observations of the faintest HII region candidates in the second and third Galactic quadrants.Together, these observations will detect the RRL emission from all Galactic HII regions with peak cm-wavelength flux densities > 60mJy, establish the outer edge of Galactic high-mass star formation, and determine the number of HII regions in the Galaxy. The HRDS and SHRDS surveys have more than doubled the known population of Galactic HII regions. We use the OSC observations to determine the properties of high-mass star formation in the extreme outer Galaxy and our VLA observations to determine how many of our faint candidates are indeed HII regions. We combine the completeness limits we obtain through these HII region surveys with an HII region population synthesis model to estimate the total number of Galactic HII regions. From this, we

PENGARUH METODE PEMBELAJARAN BERBASIS MASALAH TERHADAP SELF-EFFICACY DAN KEMAMPUAN PEMECAHAN MASALAH MATEMATIS DITINJAU DARI KEMAMPUAN AWAL MATEMATIKA SISWA SMA

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Muhammad Faruq Masri

2018-02-01

Full Text Available ABSTRACTThis study aims to investigate the ability of self-efficacy and improvement of students' mathematical problem-solving ability through learning by using Problem Based Learning (PBL methods. This study uses quasi experimental methods with final test control design for mathematical self-efficacy and pre-test post-test for mathematical problem-solving ability in terms of students' early math skills. The sample of this research is the students of class X IPA in SMA 3 and SMA 4 Kabupaten Tanggerang in odd semester of academic year 2017/2018 as many as 96 students. The result of this researh are (1 There is an improvement of mathematical problem-solving ability of students who are treated with PBL methods is better than students who get conventional learning; (2 There is an interaction between learning method and early math ability (KAM to improving students mathematical problem-solving ability; (3 There is an improvement of mathematical problem-solving ability in students with high KAM; (4 There is no improvement of mathematical problem-solving ability in students with low KAM; (5 Self-efficacy of students who are treated with PBL methods is better than students who get conventional learning; (6 There is an interaction between learning method and early math ability (KAM to self-efficacy of students; (7 There is different self-efficacy in students with high KAM; (8 There is no different of self-efficacy in students with low KAM.Keywords: Problem Based Learning, Problem-Solving Ability, Self-Efficacy

The Effectiveness of KNOS-KGS Learning Model to Improve Generic Science Skill and Biology Student Learning Outcomes SMA PGRI 1 Banjarmasin

OpenAIRE

Nefianthi, Rezky

2015-01-01

This study aims to determine the effectiveness of the model KNOS-KGS, to improve the learning outcomes of Biology at the ecosystem material in class X SMA PGRI 1 Banjarmasin. This research is a classroom action research, conducted in two cycles. Each cycle is done with two meetings. This study was conducted on 25 students in class X1. The research data is the result of student learning that consists of cognitive learning outcomes such as pretest and posttest. Affective learning outcomes such ...

UNIFORM INFALL TOWARD THE COMETARY H II REGION IN THE G34.26+0.15 COMPLEX?

Energy Technology Data Exchange (ETDEWEB)

Liu, Tie; Wu, Yuefang; Zhang, Huawei, E-mail: liutiepku@gmail.com, E-mail: ywu@pku.edu.cn [Department of Astronomy, Peking University, 100871 Beijing (China)

2013-10-10

Gas accretion is a key process in star formation. However, gas infall detections in high-mass, star-forming regions with high spatial resolution observations are rare. Here, we report the detection of gas infall toward a cometary ultracompact H II region ({sup C)} in the G34.26+0.15 complex. The observations were made with the IRAM 30 m, the James Clerk Maxwell Telescope 15 m telescope, and the Submillimeter Array (SMA). The hot core associated with 'C' has a mass of ∼76 ± 11 M{sub ☉} and a volume density of (1.1 ± 0.2) × 10{sup 8} cm{sup –3}. The HCN (3-2) and HCO{sup +} (1-0) lines observed by single dishes and the CN (2-1) lines observed by the SMA show redshifted absorption features, indicating gas infall. We found a linear relationship between the line width and optical depth of the CN (2-1) lines. Those transitions with larger optical depths and line widths have larger absorption areas. However, the infall velocities measured from different lines seem to be constant, indicating that the gas infall is uniform. We also investigated the evolution of gas infall in high-mass, star-forming regions. A tight relationship was found between the infall velocity and the total dust/gas mass. At stages prior to the hot core phase, the typical infall velocity and mass infall rate are ∼1 km s{sup –1} and ∼10{sup –4} M{sub ☉} yr{sup –1}, respectively. While in more evolved regions, the infall velocity and mass infall rates can reach as high as several km s{sup –1} and ∼10{sup –3}-10{sup –2} M{sub ☉} yr{sup –1}, respectively. Accelerated infall has been detected toward some hypercompact H II and ultracompact H II regions. However, the acceleration phenomenon is not seen in more evolved ultracompact H II regions (e.g., G34.26+0.15)

UNIFORM INFALL TOWARD THE COMETARY H II REGION IN THE G34.26+0.15 COMPLEX?

International Nuclear Information System (INIS)

Liu, Tie; Wu, Yuefang; Zhang, Huawei

2013-01-01

Gas accretion is a key process in star formation. However, gas infall detections in high-mass, star-forming regions with high spatial resolution observations are rare. Here, we report the detection of gas infall toward a cometary ultracompact H II region ( C) in the G34.26+0.15 complex. The observations were made with the IRAM 30 m, the James Clerk Maxwell Telescope 15 m telescope, and the Submillimeter Array (SMA). The hot core associated with 'C' has a mass of ∼76 ± 11 M ☉ and a volume density of (1.1 ± 0.2) × 10 8 cm –3 . The HCN (3-2) and HCO + (1-0) lines observed by single dishes and the CN (2-1) lines observed by the SMA show redshifted absorption features, indicating gas infall. We found a linear relationship between the line width and optical depth of the CN (2-1) lines. Those transitions with larger optical depths and line widths have larger absorption areas. However, the infall velocities measured from different lines seem to be constant, indicating that the gas infall is uniform. We also investigated the evolution of gas infall in high-mass, star-forming regions. A tight relationship was found between the infall velocity and the total dust/gas mass. At stages prior to the hot core phase, the typical infall velocity and mass infall rate are ∼1 km s –1 and ∼10 –4 M ☉ yr –1 , respectively. While in more evolved regions, the infall velocity and mass infall rates can reach as high as several km s –1 and ∼10 –3 -10 –2 M ☉ yr –1 , respectively. Accelerated infall has been detected toward some hypercompact H II and ultracompact H II regions. However, the acceleration phenomenon is not seen in more evolved ultracompact H II regions (e.g., G34.26+0.15)

Perbedaan hasil belajar fisika siswa antara model pembelajaran Problem Based Learning (PBL dengan model pembelajaran Prediction, Observation, and Explanation (POE di kelas X SMA Negeri 5 Lubuklinggau

Directory of Open Access Journals (Sweden)

Tri Ariani

2016-11-01

Full Text Available Penelitian ini bertujuan untuk mengetahui Perbedaan Hasil Belajar Fisika Siswa antara Model Pembelajaran Problem Based Learning (PBL dengan Model Pembelajaran Prediction, Observation, And Explanation (POE di Kelas X SMA Negeri 5 Lubuklinggau Tahun Pelajaran 2015/2016. Jenis penelitian ini adalah penelitian kuantitatif dengan metode penelitian eksperimen semu yang dilaksanakan dengan membandingkan kelompok eksperimen I dan kelompok eksperimen II desain penelitian  ini pre-test post-test group design. Populasi penelitian ini adalah seluruh siswa kelas X SMA Negeri 5 Lubuklinggau Tahun Pelajaran 2015/2016, yang terdiri dari 314 siswa dari 9 kelas. Pengambilan sampel dilakukan secara acak (Simple Random Sampling dengan cara pengundian nomor kelas populasi. Pengumpulan data berupa tes, data tes yang sudah dianalisis dengan uji-t, pada taraf  a= 0,05, diperoleh thitung > ttabel (2,17 > 2,00. Rata-rata akhir hasil belajar fisika kelas eksperimen I sebesar 73,4 sedangkan pada kelas kelas eksperimen II  sebesar 69,14. Sehingga dapat disimpulkan ada Perbedaan Hasil Belajar Fisika Siswa antara Model Pembelajaran Problem Based Learning (PBL Dengan Model Pembelajaran Prediction, Observation, And Explanation (POE Di Kelas X SMA Negeri 5 Lubuklinggau Tahun Pelajaran 2015/2016. The aim of this research was to find out the Comparative Results Between Students Studying Physics Learning Model Problem Based Learning (PBL with Learning Model Prediction, Observation, And Explanation (POE in the Class X SMAN 5 Lubuklinggau 2015/2016 Academic Year . This research was a quantitative research methods of experimental research conducted by comparing the experimental group I and group II experimental research design was a pre-test post-test group design. As the population in this research were all students of class X SMA Negeri 5 Lubuklinggau Academic Year 2015/2016, consisting of 314 students from the ninth grade. Sampling is done randomly (Simple Random Sampling by

CHANDRA IDENTIFICATION OF 26 NEW BLACK HOLE CANDIDATES IN THE CENTRAL REGION OF M31

Energy Technology Data Exchange (ETDEWEB)

Barnard, R.; Garcia, M. R.; Murray, S. S. [Harvard-Smithsonian Center for Astrophysics (CFA), Cambridge, MA 02138 (United States)

2013-06-20

We have previously identified 10 M31 black hole candidates (BHCs) in M31 from their X-ray properties alone. They exhibit ''hard state'' emission spectra that are seen at luminosities {approx}<10% Eddington in X-ray binaries (XBs) containing a neutron star (NS) or black hole, at luminosities that significantly exceed the NS threshold. Nine of these are associated with globular clusters (GCs); hence, these are most likely low mass X-ray binaries; eight are included in this survey. We have recently discovered that analysis of the long term 0.5-4.5 keV variability of XBs via structure functions allows us to separate XBs from active galactic nuclei, even though the emission spectra are often similar; this has enabled us to search for BHCs outside of GCs. We have identified 26 new BHCs (12 strong, 14 plausible) within 20' of the M31 nucleus (M31*), using 152 Chandra observations spaced over {approx}13 yr; some of our classifications were enhanced with XMM-Newton observations. Of these, seven appear within 100'' of M31*; this supports the theory suggesting that this region experiences enhanced XB production via dynamical processes similar to those seen in GCs. We have found a parameter space where our BHCs are separated from Galactic NS binaries: we show that modeling a simulated hard state spectrum with a disk blackbody + blackbody model yields parameters that lie outside the space occupied by NS binaries that are modeled this way. The probability that our BHCs all lie within the NS parameter space is {approx}3 Multiplication-Sign 10{sup -29}.

PENGEMBANGAN PROTOTIPE EGG BOILER SEBAGAI MEDIA PEMBELAJARAN PRAKARYA DAN KEWIRAUSAHAAN UNTUK MATERI TEKNOLOGI TEPAT GUNA KELAS XI MIA SMA NEGERI 4 SINGARAJA TAHUN AJARAN 2016/2017

Directory of Open Access Journals (Sweden)

Indra Kusuma Harta

2017-07-01

Full Text Available Penelitian ini bertujuan untuk mengembangkan Prototipe Egg Boiler (Pengkukus Telur Otomatis sebagai media pembelajaran untuk mata pelajaran Prakarya dan Kewirausahaan pada materi Teknologi Tepat Guna di Kelas XI MIA SMA Negeri 4 Singaraja. Penelitian ini dilakukan dengan menggunakan metode Penelitian dan Pengembangan dalam bidang pendidikan. Hasil uji validasi ahli media memperoleh skor sebesar 0,75 dalam kategori tinggi. Uji validasi isi dengan nilai sebesar 0,81 dalam kategori sangat tinggi.  Sedangkan hasil uji coba perorangan dengan nilai sebesar 0.93, uji coba kelompok kecil dengan nilai sebesar 0.71, dan uji coba lapangan dengan nilai sebesar 0.82. Pada uji coba lapangan juga dilakukan dengan menganalisis nilai dari kegiatan praktikum, nilai yang diperoleh 87.4 dikategorikan dengan hasil belajar tinggi. Dari hasil nilai pre-test dan post-test tersebut secara keseluruhan mengalami peningkatan. Sehingga Pototipe Egg Boiler yang telah dikembangkan sangat membantu siswa dalam memahami materi dan praktikum mata pelajaran Prakarya dan Kewirausahaan untuk materi Teknologi Tepat Guna di Kelas XI MIA SMA Negeri 4 Singaraja.

Speeding disease gene discovery by sequence based candidate prioritization

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Porteous David J

2005-03-01

Full Text Available Abstract Background Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is reduced by matching functional annotation to knowledge of the disease or phenotype in question. However, here we show that disease genes share patterns of sequence-based features that can provide a good basis for automatic prioritization of candidates by machine learning. Results We examined a variety of sequence-based features and found that for many of them there are significant differences between the sets of genes known to be involved in human hereditary disease and those not known to be involved in disease. We have created an automatic classifier called PROSPECTR based on those features using the alternating decision tree algorithm which ranks genes in the order of likelihood of involvement in disease. On average, PROSPECTR enriches lists for disease genes two-fold 77% of the time, five-fold 37% of the time and twenty-fold 11% of the time. Conclusion PROSPECTR is a simple and effective way to identify genes involved in Mendelian and oligogenic disorders. It performs markedly better than the single existing sequence-based classifier on novel data. PROSPECTR could save investigators looking at large regions of interest time and effort by prioritizing positional candidate genes for mutation detection and case-control association studies.

PENGARUH MODEL PEMBELAJARAN ASSURANCE, RELEVANCE, INTEREST, ASSESSMENT, SATISFACTION DENGAN STRATEGI ACTIVE LEARNING TIPE INDEX CARD MATCH TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIK SISWA SMA

Directory of Open Access Journals (Sweden)

Frasticha Frasticha

2016-08-01

Full Text Available Pemecahan masalah merupakan kegiatan matematika yang sulit baik dalam mempelajari maupun mengajarkannya, sehingga diperlukan adanya suatu model pembelajaran yang dapat memberikan pengaruh positif terhadap kemampuan pemecahan masalah siswa. Salah satu model pembelajaran yang dapat digunakan yaitu model pembelajaran ARIAS dengan strategi active learning tipe ICM. Penelitian ini bertujuan untuk mengetahui: (1 model pembelajaran ARIAS dengan strategi active learning tipe ICM berpengaruh terhadap kemampuan pemecahan masalah matematik siswa SMA; (2 Sikap siswa terhadap pembelajaran matematika menggunakan model pembelajaran ARIAS dengan strategi active learning tipe ICM. Subjek penelitian ini adalah siswa kelas XI IPA 1 dengan jumlah 38 siswa sebagai kelas kontrol dan XI IPA 2 dengan jumlah 39 siswa sebagai kelas eksperimen di SMAN 19 Kabupaten Tangerang pada tahun ajaran 2015-2016. Metode penelitian yang digunakan adalah metode penelitian eksperimen dengan adalah desain kuasi eksperimen dengan bentuk Nonequivalent Control Group serta Cluster Sampling sebagai teknik pengambilan sampel. Analisis data dalam penelitian ini menggunakan SPSS Statistics Version 22. Hasil penelitian :(1 model pembelajaran ARIAS dengan strategi active learning tipe ICM berpengaruh terhadap kemampuan pemecahan masalah matematik siswa SMA dan memberikan pengaruh yang positif; (2 sikap siswa positif terhadap model pembelajaran ARIAS dengan strategi active learning tipe ICM. Kata Kunci: Assurance Relevance Interest Assessment Satisfaction, Index Card Match, Kemampuan Pemecahan Masalah

A SYSTEMATIC SEARCH FOR MOLECULAR OUTFLOWS TOWARD CANDIDATE LOW-LUMINOSITY PROTOSTARS AND VERY LOW LUMINOSITY OBJECTS

Energy Technology Data Exchange (ETDEWEB)

Schwarz, Kamber R.; Shirley, Yancy L. [Steward Observatory, 933 N. Cherry Ave., Tucson, AZ 85721 (United States); Dunham, Michael M. [Department of Astronomy, Yale University, P.O. Box 208101, New Haven, CT 06520 (United States)

2012-10-01

We present a systematic single-dish search for molecular outflows toward a sample of nine candidate low-luminosity protostars and 30 candidate very low luminosity objects (VeLLOs; L{sub int} {<=} 0.1 L{sub Sun }). The sources are identified using data from the Spitzer Space Telescope cataloged by Dunham et al. toward nearby (D < 400 pc) star-forming regions. Each object was observed in {sup 12}CO and {sup 13}CO J = 2 {yields} 1 simultaneously using the sideband separating ALMA Band-6 prototype receiver on the Heinrich Hertz Telescope at 30'' resolution. Using five-point grid maps, we identify five new potential outflow candidates and make on-the-fly maps of the regions surrounding sources in the dense cores B59, L1148, L1228, and L1165. Of these new outflow candidates, only the map of B59 shows a candidate blue outflow lobe associated with a source in our survey. We also present larger and more sensitive maps of the previously detected L673-7 and the L1251-A-IRS4 outflows and analyze their properties in comparison to other outflows from VeLLOs. The accretion luminosities derived from the outflow properties of the VeLLOs with detected CO outflows are higher than the observed internal luminosity of the protostars, indicating that these sources likely had higher accretion rates in the past. The known L1251-A-IRS3 outflow is detected but not re-mapped. We do not detect clear, unconfused signatures of red and blue molecular wings toward the other 31 sources in the survey indicating that large-scale, distinct outflows are rare toward this sample of candidate protostars. Several potential outflows are confused with the kinematic structure in the surrounding core and cloud. Interferometric imaging is needed to disentangle large-scale molecular cloud kinematics from these potentially weak protostellar outflows.

ANALISIS SOAL JENJANG KOGNITIF TAKSONOMI BLOOM REVISI PADA BUKU SEKOLAH ELEKTRONIK (BSE BIOLOGI SMA

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Aa Juhanda

2016-11-01

Penelitian ini bertujuan untuk menganalisis kemunculan soal jenjang kognitif Bloom Revisi pada Buku Sekolah Elektronik (BSE Biologi SMA. Subjek penelitian adalah 1.650 soal yang terdapat pada BSE Edisi 2009. Instrumen yang digunakan adalah lembar analisis dokumen yang di dalamnya memuat informasi seperti kode soal, soal, dan jenis tingkatan kognitif taksonomi Bloom Revisi. Analisis data dilakukan secara kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa rerata persentase kemunculan cukup tinggi diperoleh pada soal yang mengembangkan keterampilan berpikir tingkat rendah (Lower-Order Thinking Skills yaitu soal C1 (mengingat sebesar 46,60% dan C2 (memahami sebesar 47,99%, meskipun untuk C3 (menerapkan persentasenya masih rendah (0,28%. Rerata persentase kemunculan soal yang mengembangkan keterampilan tingkat tinggi (Higher-Order Thinking Skills mulai dari soal C4 (menganalisis sampai dengan C6 (mencipta memiliki rerata persentase yang rendah. Oleh karena itu, kemunculan soal jenjang kognitif Bloom Revisi pada BSE khususnya yang mengembangkan Higher-Order Thinking Skills masih perlu untuk ditingkatkan.

A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder

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David G Ashbrook

2015-07-01

Full Text Available Bipolar disorder (BD is a significant neuropsychiatric disorder with a lifetime prevalence of ~1%. To identify genetic variants underlying BD genome-wide association studies (GWAS have been carried out. While many variants of small effect associated with BD have been identified few have yet been confirmed, partly because of the low power of GWAS due to multiple comparisons being made. Complementary mapping studies using murine models have identified genetic variants for behavioral traits linked to BD, often with high power, but these identified regions often contain too many genes for clear identification of candidate genes. In the current study we have aligned human BD GWAS results and mouse linkage studies to help define and evaluate candidate genes linked to BD, seeking to use the power of the mouse mapping with the precision of GWAS. We use quantitative trait mapping for open field test and elevated zero maze data in the largest mammalian model system, the BXD recombinant inbred mouse population, to identify genomic regions associated with these BD-like phenotypes. We then investigate these regions in whole genome data from the Psychiatric Genomics Consortium’s bipolar disorder GWAS to identify candidate genes associated with BD. Finally we establish the biological relevance and pathways of these genes in a comprehensive systems genetics analysis.We identify four genes associated with both mouse anxiety and human BD. While TNR is a novel candidate for BD, we can confirm previously suggested associations with CMYA5, MCTP1 and RXRG. A cross-species, systems genetics analysis shows that MCTP1, RXRG and TNR coexpress with genes linked to psychiatric disorders and identify the striatum as a potential site of action. CMYA5, MCTP1, RXRG and TNR are associated with mouse anxiety and human BD. We hypothesize that MCTP1, RXRG and TNR influence intercellular signaling in the striatum.

Infrared study of new star cluster candidates associated to dusty globules

Science.gov (United States)

Soto King, P.; Barbá, R.; Roman-Lopes, A.; Jaque, M.; Firpo, V.; Nilo, J. L.; Soto, M.; Minniti, D.

2014-10-01

We present results from a study of a sample of small star clusters associated to dusty globules and bright-rimmed clouds that have been observed under ESO/Chile public infrared survey Vista Variables in the Vía Láctea (VVV). In this short communication, we analyse the near-infrared properties of a set of four small clusters candidates associated to dark clouds. This sample of clusters associated to dusty globules are selected from the new VVV stellar cluster candidates developed by members of La Serena VVV Group (Barbá et al. 2014). Firstly, we are producing color-color and color-magnitude diagrams for both, cluster candidates and surrounding areas for comparison through PSF photometry. The cluster positions are determined from the morphology on the images and also from the comparison of the observed luminosity function for the cluster candidates and the surrounding star fields. Now, we are working in the procedures to establish the full sample of clusters to be analyzed and methods for subtraction of the star field contamination. These clusters associated to dusty globules are simple laboratories to study the star formation relatively free of the influence of large star-forming regions and populous clusters, and they will be compared with those clusters associated to bright-rimmed globules, which are influenced by the energetic action of nearby O and B massive stars.

11 CFR 100.154 - Candidate debates.

Science.gov (United States)

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Candidate debates. 100.154 Section 100.154 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) Exceptions to Expenditures § 100.154 Candidate debates. Funds used to defray costs incurred in staging candidate debates in...

11 CFR 100.92 - Candidate debates.

Science.gov (United States)

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Candidate debates. 100.92 Section 100.92 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) Exceptions to Contributions § 100.92 Candidate debates. Funds provided to defray costs incurred in staging candidate debates...

Molecular Gas toward the Gemini OB1 Molecular Cloud Complex. II. CO Outflow Candidates with Possible WISE Associations

Science.gov (United States)

Li, Yingjie; Li, Fa-Cheng; Xu, Ye; Wang, Chen; Du, Xin-Yu; Yang, Wenjin; Yang, Ji

2018-03-01

We present a large-scale survey of CO outflows in the Gem OB1 molecular cloud complex and its surroundings, using the Purple Mountain Observatory Delingha 13.7 m telescope. A total of 198 outflow candidates were identified over a large area (∼58.5 square degrees), of which 193 are newly detected. Approximately 68% (134/198) are associated with the Gem OB1 molecular cloud complex, including clouds GGMC 1, GGMC 2, BFS 52, GGMC 3, and GGMC 4. Other regions studied are: the Local arm (Local Lynds, West Front), Swallow, Horn, and Remote cloud. Outflow candidates in GGMC 1, BFS 52, and Swallow are mainly located at ring-like or filamentary structures. To avoid excessive uncertainty in distant regions (≳3.8 kpc), we only estimated the physical parameters for clouds in the Gem OB1 molecular cloud complex and in the Local arm. In those clouds, the total kinetic energy and the energy injection rate of the identified outflow candidates are ≲1% and ≲3% of the turbulent energy and the turbulent dissipation rate of each cloud, indicating that the identified outflow candidates cannot provide enough energy to balance turbulence of their host cloud at the scale of the entire cloud (several to dozens of parsecs). The gravitational binding energy of each cloud is ≳135 times the total kinetic energy of the identified outflow candidates within the corresponding cloud, indicating that the identified outflow candidates cannot cause major disruptions to the integrity of their host cloud at the scale of the entire cloud.

CHEMICAL SEGREGATION TOWARD MASSIVE HOT CORES: THE AFGL2591 STAR-FORMING REGION

Energy Technology Data Exchange (ETDEWEB)

Jimenez-Serra, I.; Zhang, Q. [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States); Viti, S. [Department of Physics and Astronomy, University College London, Gower Place, London WC1E 6BT (United Kingdom); Martin-Pintado, J. [Centro de Astrobiologia (CSIC/INTA), Ctra. de Torrejon a Ajalvir km 4, E-28850 Torrejon de Ardoz, Madrid (Spain); De Wit, W.-J., E-mail: ijimenez-serra@cfa.harvard.edu, E-mail: qzhang@cfa.harvard.edu, E-mail: sv@star.ucl.ac.uk, E-mail: jmartin@cab.inta-csic.es, E-mail: wdewit@eso.org [European Southern Observatory, Alonso de Cordova 3107, Vitacura, Santiago (Chile)

2012-07-01

We present high angular resolution observations (0.''5 Multiplication-Sign 0.''3) carried out with the Submillimeter Array (SMA) toward the AFGL2591 high-mass star-forming region. Our SMA images reveal a clear chemical segregation within the AFGL2591 VLA 3 hot core, where different molecular species (Types I, II, and III) appear distributed in three concentric shells. This is the first time that such a chemical segregation is ever reported at linear scales {<=}3000 AU within a hot core. While Type I species (H{sub 2}S and {sup 13}CS) peak at the AFGL2591 VLA 3 protostar, Type II molecules (HC{sub 3}N, OCS, SO, and SO{sub 2}) show a double-peaked structure circumventing the continuum peak. Type III species, represented by CH{sub 3}OH, form a ring-like structure surrounding the continuum emission. The excitation temperatures of SO{sub 2}, HC{sub 3}N, and CH{sub 3}OH (185 {+-} 11 K, 150 {+-} 20 K, and 124 {+-} 12 K, respectively) show a temperature gradient within the AFGL2591 VLA 3 envelope, consistent with previous observations and modeling of the source. By combining the H{sub 2}S, SO{sub 2}, and CH{sub 3}OH images, representative of the three concentric shells, we find that the global kinematics of the molecular gas follow Keplerian-like rotation around a 40 M{sub Sun} star. The chemical segregation observed toward AFGL2591 VLA 3 is explained by the combination of molecular UV photodissociation and a high-temperature ({approx}1000 K) gas-phase chemistry within the low extinction innermost region in the AFGL2591 VLA 3 hot core.

On the physical nature of globular cluster candidates in the Milky Way bulge

Science.gov (United States)

Piatti, Andrés E.

2018-06-01

We present results from 2MASS JKs photometry on the physical reality of recently reported globular cluster (GC) candidates in the Milky Way (MW) bulge. We relied our analysis on photometric membership probabilities that allowed us to distinguish real stellar aggregates from the composite field star population. When building colour-magnitude diagrams and stellar density maps for stars at different membership probability levels, the genuine GC candidate populations are clearly highlighted. We then used the tip of the red giant branch (RGB) as distance estimator, resulting in heliocentric distances that place many of the objects in regions near the MW bulge, where no GC had been previously recognized. Some few GC candidates resulted to be MW halo/disc objects. Metallicities estimated from the standard RGB method are in agreement with the values expected according to the position of the GC candidates in the Galaxy. Finally, we derived, for the first time, their structural parameters. We found that the studied objects have core, half-light, and tidal radii in the ranges spanned by the population of known MW GCs. Their internal dynamical evolutionary stages will be described properly when their masses are estimated.

Near-Earth Asteroid 2005 CR37: Radar Images and Photometry of a Candidate Contact Binary

Science.gov (United States)

Benner, Lance A. M.; Nolan, Michael C.; Ostro, Steven J.; Giorgini, Jon D.; Pray, Donald P.; Harris, Alan W.; Magri, Christopher; Margot, Jean-Luc

2006-01-01

Arecibo (2380 MHz, 13 cm) radar observations of 2005 CR37 provide detailed images of a candidate contact binary: a 1.8-km-long, extremely bifurcated object. Although the asteroid's two lobes are round, there are regions of modest topographic relief, such as an elevated, 200-m-wide facet, that suggest that the lobes are geologically more complex than either coherent fragments or homogeneous rubble piles. Since January 1999, about 9% of NEAs larger than approx.200 m imaged by radar can be described as candidate contact binaries.

Computed tomographic findings in acute superior mesenteric arterial occlusion

International Nuclear Information System (INIS)

Kuwabara, Yoshiyuki; Kataoka, Makoto; Kureyama, Yasuyuki; Iwata, Hiroshi; Kashima, Taketoshi; Sinoda, Noriyuki; Sato, Atsushi; Hattori, Kohji; Masaoka, Akira

1993-01-01

In this study computed tomography (CT) findings were examined in 6 cases of acute superior mesenteric arterial (SMA) occlusion. With simple CT, occluded site of SMA revealed a slightly high density in 2 cases, while no findings were noted in other cases. Slightly dilated multiple loops of the intestine were confirmed in 3 cases, but no particular changes in the intestinal wall were found. As other findings, ascites and air in the portal vein were found in each one case. Contrast enhanced CT was conducted in 2 out of the 6 cases, and occluded site was visualized as spots in one case but no findings were noted in the other. The contrast enhancement effect in vessels in SMA region was examined from its root to the peripheral in this order, and the 2 cases showed common findings that the contrast enhancement effect abruptly disappeared at a point in vessels in SMA region (discontinuance). The point was consistent with the occluded site on angiography. These findings indicate that simple CT alone is difficult to offer correct diagnosis of SMA occlusion, but contrast enhanced CT is able to visualize the SMA occlusion as a discontinuance picture. It is thought that contrast enhanced CT can be a useful procedure for early diagnosis of SMA occlusion. (author)

Identification of candidate genes for dyslexia susceptibility on chromosome 18.

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Thomas S Scerri

2010-10-01

Full Text Available Six independent studies have identified linkage to chromosome 18 for developmental dyslexia or general reading ability. Until now, no candidate genes have been identified to explain this linkage. Here, we set out to identify the gene(s conferring susceptibility by a two stage strategy of linkage and association analysis.Linkage analysis: 264 UK families and 155 US families each containing at least one child diagnosed with dyslexia were genotyped with a dense set of microsatellite markers on chromosome 18. Association analysis: Using a discovery sample of 187 UK families, nearly 3000 SNPs were genotyped across the chromosome 18 dyslexia susceptibility candidate region. Following association analysis, the top ranking SNPs were then genotyped in the remaining samples. The linkage analysis revealed a broad signal that spans approximately 40 Mb from 18p11.2 to 18q12.2. Following the association analysis and subsequent replication attempts, we observed consistent association with the same SNPs in three genes; melanocortin 5 receptor (MC5R, dymeclin (DYM and neural precursor cell expressed, developmentally down-regulated 4-like (NEDD4L.Along with already published biological evidence, MC5R, DYM and NEDD4L make attractive candidates for dyslexia susceptibility genes. However, further replication and functional studies are still required.

A candidate syntenic genetic locus is associated with voluntary exercise levels in mice and humans

NARCIS (Netherlands)

Kostrzewa, E.; Brandys, M. K.; van Lith, H. A.; Kas, M. J H

2015-01-01

Individual levels of physical activity, and especially of voluntary physical exercise, highly contribute to the susceptibility for developing metabolic, cardiovascular diseases, and potentially to psychiatric disorders. Here, we applied a cross-species approach to explore a candidate genetic region

HIGH ANGULAR RESOLUTION OBSERVATIONS OF FOUR CANDIDATE BLAST HIGH-MASS STARLESS CORES

International Nuclear Information System (INIS)

Olmi, Luca; Poventud, Carlos M.; Araya, Esteban D.; Chapin, Edward L.; Gibb, Andrew; Hofner, Peter; Martin, Peter G.

2010-01-01

We discuss high angular resolution observations of ammonia toward four candidate high-mass starless cores (HMSCs). The cores were identified by the Balloon-borne Large Aperture Submillimeter Telescope (BLAST) during its 2005 survey of the Vulpecula region where 60 compact sources were detected simultaneously at 250, 350, and 500 μm. Four of these cores, with no IRAS-PSC or MSX counterparts, were mapped with the NRAO Very Large Array and observed with the Effelsberg 100 m telescope in the NH 3 (1,1) and (2,2) spectral lines. Our observations indicate that the four cores are cold (T k -1 . The four BLAST cores appear to be colder and more quiescent than other previously observed HMSC candidates, suggesting an earlier stage of evolution.

Genome-Wide Association Study with Sequence Variants Identifies Candidate Genes for Mastitis Resistance in Dairy Cattle

DEFF Research Database (Denmark)

Sahana, Goutam; Guldbrandtsen, Bernt; Bendixen, Christian

Six genomic regions affecting clinical mastitis were identified through a GWAS study with imputed BovineHD chip genotype data in the Nordic Holstein cattle population. The association analyses were carried out using a SNP-by-SNP analysis by fitting the regression of allele dosage and a polygenic...... Effect Predictor (VEP) vers. 2.6 using ENSEMBL vers. 67 databases. Candidate polymorphisms affecting clinical mastitis were selected based on their association with the traits and functional annotations. A strong positional candidate gene for mastitis resistance on chromosome-6 is the NPFFR2 which...... Factor Receptor Alpha (LIFR) emerged as a strong candidate gene for mastitis resistance. The LIFR gene is involved in acute phase response and is expressed in saliva and mammary gland....

Multiscale Modeling of Polycrystalline NiTi Shape Memory Alloy under Various Plastic Deformation Conditions by Coupling Microstructure Evolution and Macroscopic Mechanical Response.

Science.gov (United States)

Hu, Li; Jiang, Shuyong; Zhou, Tao; Tu, Jian; Shi, Laixin; Chen, Qiang; Yang, Mingbo

2017-10-13

Numerical modeling of microstructure evolution in various regions during uniaxial compression and canning compression of NiTi shape memory alloy (SMA) are studied through combined macroscopic and microscopic finite element simulation in order to investigate plastic deformation of NiTi SMA at 400 °C. In this approach, the macroscale material behavior is modeled with a relatively coarse finite element mesh, and then the corresponding deformation history in some selected regions in this mesh is extracted by the sub-model technique of finite element code ABAQUS and subsequently used as boundary conditions for the microscale simulation by means of crystal plasticity finite element method (CPFEM). Simulation results show that NiTi SMA exhibits an inhomogeneous plastic deformation at the microscale. Moreover, regions that suffered canning compression sustain more homogeneous plastic deformation by comparison with the corresponding regions subjected to uniaxial compression. The mitigation of inhomogeneous plastic deformation contributes to reducing the statistically stored dislocation (SSD) density in polycrystalline aggregation and also to reducing the difference of stress level in various regions of deformed NiTi SMA sample, and therefore sustaining large plastic deformation in the canning compression process.

Multiscale Modeling of Polycrystalline NiTi Shape Memory Alloy under Various Plastic Deformation Conditions by Coupling Microstructure Evolution and Macroscopic Mechanical Response

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Li Hu

2017-10-01

Full Text Available Numerical modeling of microstructure evolution in various regions during uniaxial compression and canning compression of NiTi shape memory alloy (SMA are studied through combined macroscopic and microscopic finite element simulation in order to investigate plastic deformation of NiTi SMA at 400 °C. In this approach, the macroscale material behavior is modeled with a relatively coarse finite element mesh, and then the corresponding deformation history in some selected regions in this mesh is extracted by the sub-model technique of finite element code ABAQUS and subsequently used as boundary conditions for the microscale simulation by means of crystal plasticity finite element method (CPFEM. Simulation results show that NiTi SMA exhibits an inhomogeneous plastic deformation at the microscale. Moreover, regions that suffered canning compression sustain more homogeneous plastic deformation by comparison with the corresponding regions subjected to uniaxial compression. The mitigation of inhomogeneous plastic deformation contributes to reducing the statistically stored dislocation (SSD density in polycrystalline aggregation and also to reducing the difference of stress level in various regions of deformed NiTi SMA sample, and therefore sustaining large plastic deformation in the canning compression process.

Input Files and Procedures for Analysis of SMA Hybrid Composite Beams in MSC.Nastran and ABAQUS

Science.gov (United States)

Turner, Travis L.; Patel, Hemant D.

2005-01-01

A thermoelastic constitutive model for shape memory alloys (SMAs) and SMA hybrid composites (SMAHCs) was recently implemented in the commercial codes MSC.Nastran and ABAQUS. The model is implemented and supported within the core of the commercial codes, so no user subroutines or external calculations are necessary. The model and resulting structural analysis has been previously demonstrated and experimentally verified for thermoelastic, vibration and acoustic, and structural shape control applications. The commercial implementations are described in related documents cited in the references, where various results are also shown that validate the commercial implementations relative to a research code. This paper is a companion to those documents in that it provides additional detail on the actual input files and solution procedures and serves as a repository for ASCII text versions of the input files necessary for duplication of the available results.

Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study

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Close Eimear

2010-05-01

Full Text Available Abstract Background Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance. The majority of newly associated regions encode candidate genes with a clear functional role in T-cell regulation. Furthermore, the newly discovered risk loci, together with the well established HLA locus, account for less than 50% of the heritability of CD, suggesting that numerous additional loci remain undiscovered. Linkage studies have identified some well-replicated risk regions, most notably chromosome 5q31 and 11q23. Methods We have evaluated six candidate genes in one of these regions (11q23, namely CD3E, CD3D, CD3G, IL10RA, THY1 and IL18, as risk factors for CD using a 2-phase candidate gene approach directed at chromosome 11q. 377 CD cases and 349 ethnically matched controls were used in the initial screening, followed by an extended sample of 171 additional coeliac cases and 536 additional controls. Results Promotor SNPs (-607, -137 in the IL18 gene, which has shown association with several autoimmune diseases, initially suggested association with CD (P IL18-137/-607 also supported this effect, primarily due to one relatively rare haplotype IL18-607C/-137C (P Conclusion Haplotypes of the IL18 promotor region may contribute to CD risk, consistent with this cytokine's role in maintaining inflammation in active CD.

Influence on SME and microstructure in FeMnSiCrNi SMA for strengthening of austenite matrix

International Nuclear Information System (INIS)

Gu, N.; Lin, C.; Song, X.; Peng, H.; Yin, F.

2000-01-01

Influences of solution- and deformation-strengthening on SME and the microstructures of FeMnSiCrNi SMA were researched. SME and the training effect were both obviously improved when 0.3%C added into the alloy. It was observed that some thermo-induced martensites, distributing disorderly in the matrix, formed in the alloy without carbon, while in the alloy with carbon, more stress-induced martensites, distributing orderly in the matrix, were found, thus resulting in the better SME. As far as the treatment methods were concerned, one time deformation-strengthening could be better than training many times. The ε-martensites in the strengthened alloy appeared larger in amount, short plate in shape and distributed with nearly the same orientation, which is closely related to the better SME. (orig.)

Sequence-Based Introgression Mapping Identifies Candidate White Mold Tolerance Genes in Common Bean

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Sujan Mamidi

2016-07-01

Full Text Available White mold, caused by the necrotrophic fungus (Lib. de Bary, is a major disease of common bean ( L.. WM7.1 and WM8.3 are two quantitative trait loci (QTL with major effects on tolerance to the pathogen. Advanced backcross populations segregating individually for either of the two QTL, and a recombinant inbred (RI population segregating for both QTL were used to fine map and confirm the genetic location of the QTL. The QTL intervals were physically mapped using the reference common bean genome sequence, and the physical intervals for each QTL were further confirmed by sequence-based introgression mapping. Using whole-genome sequence data from susceptible and tolerant DNA pools, introgressed regions were identified as those with significantly higher numbers of single-nucleotide polymorphisms (SNPs relative to the whole genome. By combining the QTL and SNP data, WM7.1 was located to a 660-kb region that contained 41 gene models on the proximal end of chromosome Pv07, while the WM8.3 introgression was narrowed to a 1.36-Mb region containing 70 gene models. The most polymorphic candidate gene in the WM7.1 region encodes a BEACH-domain protein associated with apoptosis. Within the WM8.3 interval, a receptor-like protein with the potential to recognize pathogen effectors was the most polymorphic gene. The use of gene and sequence-based mapping identified two candidate genes whose putative functions are consistent with the current model of pathogenicity.

PENGEMBANGAN PERANGKAT PEMBELAJARAN BIOLOGI BERORIENTASI PENGEMBANGAN KECERDASAN MAJEMUK SISWA PADA KONSEP SEL KELAS XI SMA

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Vidya Chaerunnisa

2017-01-01

Full Text Available This study aimed to determine the feasibility of the development of student’s multiple intelligence-oriented learning instrument on the cells concept in grade XI senior high school. Research and Development (R & D method was conducted in this research. This research was developed four components in the cell concept learning instrument that included syllabus, lesson plan, student’s worksheet, and assessment instrument. From the four components were obtained an average score of 93.76% with a decent category. The time limited test was conducted in July-August 2016, at SMAN 4 Kota Serang and SMA Prisma Sanjaya Kota Serang. Based on students' responses as a user, it was obtained the value of 79.78% with a fair category. Based on the results of expert test and limited test scale, the learning instrument development of multiple intelligences learning-oriented can be applied for the learning process in the cell concept for grade XI in senior high school.

Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate

DEFF Research Database (Denmark)

Esen, Meral; Kremsner, Peter G; Schleucher, Regina

2009-01-01

Malaria is a major public health problem in Sub-Saharan Africa. In highly endemic regions infants, children and pregnant women are mostly affected. An effective malaria vaccine would complement existing malaria control strategies because it can be integrated in existing immunization programs easily....... Here we present the results of the first phase Ia clinical trial of GMZ2 adjuvanted in aluminium hydroxide. GMZ2 is a malaria vaccine candidate, designed upon the rationale to induce immune responses against asexual blood stages of Plasmodium falciparum similar to those encountered in semi...... is a safe and immunogenic malaria vaccine candidate suitable for further clinical development....

The role of the core in degeneracy of chiral candidate band doubling

International Nuclear Information System (INIS)

Timar, J.; Sohler, D.; Vaman, C.; SUNY, Stony Brook, NY; Starosta, K.; Fossan, D.B.; Koike, T.; Tohoku Univ., Sendai; Lee, I.Y.; Macchiavelli, A.O.

2005-01-01

Complete text of publication follows. Nearly degenerate ΔI=1 rotational bands have been observed recently in several odd-odd nuclei in the A ∼ 130 and A ∼ 100 mass regions. The properties of these doublet bands have been found to agree with the scenario of spontaneous formation of chirality and disagree with other possible scenarios. However, the most recent results obtained from life-time experiments for some chiral candidate nuclei in the A ∼ 130 mass region seem to contradict the chiral interpretation of the doublet bands in these nuclei based on the observed differences in the absolute electromagnetic transition rates; the transition rates expected for chiral doublets are predicted to be very similar. Therefore it is interesting to search for new types of experimental data that may provide further possibilities to distinguish between alternative interpretations, and may uncover new properties of the mechanism that is responsible for the band doubling in these nuclei. Such a new type of experimental data was found by studying the chiral candidate bands in neighboring Rh nuclei. High-spin states of 103 Rh were studied using the 96 Zr( 11 B,4n) reaction at 40 MeV beam energy and chiral partner candidate bands have been found in it. As a result of this observation a special quartet of neighboring chiral candidate nuclei can be investigated for the first time. With this quartet identified a comparison between the behavior of the nearly degenerate doublet bands belonging to the same core but to different valence quasiparticle configurations, as well as belonging to different cores but to the same valence quasiparticle configuration, becomes possible. The comparison shows that the energy separation of these doublet band structures depends mainly on the core properties and only at less extent on the valence quasiparticle coupling. This observation sets up new criteria for the explanations of the band doublings, restricting the possible scenarios and providing

A genome-wide association study for body weight in Japanese Thoroughbred racehorses clarifies candidate regions on chromosomes 3, 9, 15, and 18

Science.gov (United States)

TOZAKI, Teruaki; KIKUCHI, Mio; KAKOI, Hironaga; HIROTA, Kei-ichi; NAGATA, Shun-ichi

2017-01-01

ABSTRACT Body weight is an important trait to confirm growth and development in humans and animals. In Thoroughbred racehorses, it is measured in the postnatal, training, and racing periods to evaluate growth and training degrees. The body weight of mature Thoroughbred racehorses generally ranges from 400 to 600 kg, and this broad range is likely influenced by environmental and genetic factors. Therefore, a genome-wide association study (GWAS) using the Equine SNP70 BeadChip was performed to identify the genomic regions associated with body weight in Japanese Thoroughbred racehorses using 851 individuals. The average body weight of these horses was 473.9 kg (standard deviation: 28.0) at the age of 3, and GWAS identified statistically significant SNPs on chromosomes 3 (BIEC2_808466, P=2.32E-14), 9 (BIEC2_1105503, P=1.03E-7), 15 (BIEC2_322669, P=9.50E-6), and 18 (BIEC2_417274, P=1.44E-14), which were associated with body weight as a quantitative trait. The genomic regions on chromosomes 3, 9, 15, and 18 included ligand-dependent nuclear receptor compressor-like protein (LCORL), zinc finger and AT hook domain containing (ZFAT), tribbles pseudokinase 2 (TRIB2), and myostatin (MSTN), respectively, as candidate genes. LCORL and ZFAT are associated with withers height in horses, whereas MSTN affects muscle mass. Thus, the genomic regions identified in this study seem to affect the body weight of Thoroughbred racehorses. Although this information is useful for breeding and growth management of the horses, the production of genetically modified animals and gene doping (abuse/misuse of gene therapy) should be prohibited to maintain horse racing integrity. PMID:29270069

PENDIDIKAN KARAKTER POLA MUHAMMADIYAH (Studi Kasus SMA Muhammadiyah 1 dan MA Muallimin Yogyakarta

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Kuswono Kuswono

2013-09-01

Full Text Available This research aims to find out the sources of character education at Islamic schools, character- building values application and actualization. This research was conducted in SMA Mubammadiyah I Yogyakarta and MA Muallimin Muhammadiyah Yogyakarta.The result of research showed that teacher's perception on character education relied on Islamic precepts to create akhakul karimah-human beings. The sources of character education included Quran and as=Sunnah/Hadist as well as Ijtihad. The character value implantation was carried out through learning in the classroom, precedents from figures, teachers and peers, well-behaving familiarization in the presence of rule and order, personality report, and extracurricular activities in knowledge, skill, sport, art, and organization fields. The form of character-building values actualization emphasized more on the Islamic activities such as collectively shalat, reading and reciting Quran, social service, participating actively in IPM, hizbul wathan, and tapak suci organizational activities. In addition, there were kader inti/an, mubalig jumat, mubalig hijarah, fasting, Friday sermon, becoming the orator in pengajian, and flag ceremony. Such these activities reflected on religious, cooperative, leadership, loving-to-homeland, social care, environmental care, and creative values.Keywords: Education, Character, Muhammadiyah.

Dark matter candidates

International Nuclear Information System (INIS)

Turner, M.S.

1989-01-01

One of the simplest, yet most profound, questions we can ask about the Universe is, how much stuff is in it, and further what is that stuff composed of? Needless to say, the answer to this question has very important implications for the evolution of the Universe, determining both the ultimate fate and the course of structure formation. Remarkably, at this late date in the history of the Universe we still do not have a definitive answer to this simplest of questions---although we have some very intriguing clues. It is known with certainty that most of the material in the Universe is dark, and we have the strong suspicion that the dominant component of material in the Cosmos is not baryons, but rather is exotic relic elementary particles left over from the earliest, very hot epoch of the Universe. If true, the Dark Matter question is a most fundamental one facing both particle physics and cosmology. The leading particle dark matter candidates are: the axion, the neutralino, and a light neutrino species. All three candidates are accessible to experimental tests, and experiments are now in progress. In addition, there are several dark horse, long shot, candidates, including the superheavy magnetic monopole and soliton stars. 13 refs

Association study of candidate genes for susceptibility to schizophrenia and bipolar disorder on chromosome 22Q13

DEFF Research Database (Denmark)

Severinsen, Jacob; Binderup, Helle; Mors, Ole

Chromosome 22q is suspected to harbor risk genes for schizophrenia as well as bipolar affective disorder. This is evidenced through genetic mapping studies, investigations of cytogenetic abnormalities, and direct examination of candidate genes. In a recent study of distantly related patients from...... the Faroe Islands we have obtained evidence suggesting two regions on chromosome 22q13 to potentially harbor susceptibility genes for both schizophrenia and bipolar affective disorder. We have selected a number of candidate genes from these two regions for further analysis, including the neuro-gene WKL1...... and unrelated controls, and in a Scottish case-control sample comprising 200 schizophrenics, 200 bipolar patients and 200 controls. None of the investigated SNPs have so far showed strong evidence of association to either bipolar disorder or schizophrenia....

Toward a regional power plant siting method: AEC-Maryland regional siting factors study, FY 1974 progress report

International Nuclear Information System (INIS)

Yaffee, S.L.; Miller, C.A.

1974-11-01

The ''AEC-Maryland Regional Siting Factors Study'' examines the process of siting in a regional context. It is developing an analysis method to delineate candidate areas for siting of several power plant technology packages, including both fossil-fueled and nuclear options. Tools that are being used include simulation modeling, economic and demographic forecasting, spatial analysis, and computer graphics and numerical manipulation. The approach will describe the trade-offs incurred if a power plant is located in one candidate area rather than in another. In FY 1974, a suitability analysis method was developed which uses engineering and environmental parameters to define a level of environmental cost incurred if a segment of land is used to site a specific technology package. (U.S.)

Parkinson-related changes of activation in visuomotor brain regions during perceived forward self-motion.

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Anouk van der Hoorn

Full Text Available Radial expanding optic flow is a visual consequence of forward locomotion. Presented on screen, it generates illusionary forward self-motion, pointing at a close vision-gait interrelation. As particularly parkinsonian gait is vulnerable to external stimuli, effects of optic flow on motor-related cerebral circuitry were explored with functional magnetic resonance imaging in healthy controls (HC and patients with Parkinson's disease (PD. Fifteen HC and 22 PD patients, of which 7 experienced freezing of gait (FOG, watched wide-field flow, interruptions by narrowing or deceleration and equivalent control conditions with static dots. Statistical parametric mapping revealed that wide-field flow interruption evoked activation of the (pre-supplementary motor area (SMA in HC, which was decreased in PD. During wide-field flow, dorsal occipito-parietal activations were reduced in PD relative to HC, with stronger functional connectivity between right visual motion area V5, pre-SMA and cerebellum (in PD without FOG. Non-specific 'changes' in stimulus patterns activated dorsolateral fronto-parietal regions and the fusiform gyrus. This attention-associated network was stronger activated in HC than in PD. PD patients thus appeared compromised in recruiting medial frontal regions facilitating internally generated virtual locomotion when visual motion support falls away. Reduced dorsal visual and parietal activations during wide-field optic flow in PD were explained by impaired feedforward visual and visuomotor processing within a magnocellular (visual motion functional chain. Compensation of impaired feedforward processing by distant fronto-cerebellar circuitry in PD is consistent with motor responses to visual motion stimuli being either too strong or too weak. The 'change'-related activations pointed at covert (stimulus-driven attention.

Academic Dishonesty Tendencies and Values of Teacher Candidates

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Ayşegül KADI

2016-12-01

Full Text Available The purpose of this study was to examine the values and academic dishonesty tendencies of teacher candidates. The population of this study included teacher candidates who received pedagogic formation education during 2013-2014 academic semester at the Faculty of Education at Ege University. The study was conducted with 244 teacher candidates, who were chosen through convenient sampling method. Academic Dishonesty Tendency Scale and Portrait Values Questionnaire were used to collect data. It was a correlational study due to the investigation of the relationship between values and academic dishonesty tendencies of teacher candidates. It was also a survey study since the academic dishonesty tendencies and values of teacher candidates were examined in relation to demographic variables. The results suggested that there wass a significant difference between the values and academic dishonesty tendencies of teacher candidates for gender variable. The values and academic dishonesty tendencies of teacher candidates did not differ for different fields of study. There was not a significant relationship between the academic dishonesty tendencies and values of teacher candidates.

Spectral mixture analysis (SMA and change vector analysis (CVA methods for monitoring and mapping land degradation/desertification in arid and semiarid areas (Sudan, using Landsat imagery

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Abdelrahim A.M. Salih

2017-04-01

Full Text Available The severe Sahel catastrophe in 1968–1974 as well as repeated famines and food shortage that have hit many African countries during the 1970s have highlighted the need for further research concerning land degradation and environmental monitoring in arid and semi-arid areas. Land degradation, and desertification processes in arid and semi-arid environment were increased in the last four decades, especially in the developing countries like Sudan. To test to what extent remote sensing and geographical information science (GIS methodologies and techniques could be used for monitoring changes in arid and semi-arid regions and environment, these methodologies have long been suggested as a time and cost-efficient method. In this frame, spectral Mixture Analysis (SMA, Object-based oriented classification (Segmentation, and Change Vector Analysis are recently much recommended as a most suitable method for monitoring and mapping land cover changes in arid and semi-arid environment. Therefor the aim of this study is to use these methods and techniques for environmental monitoring with emphasis on desertification and to find model that can describe and map the status and rate of desertification processes and land cover changes in semi-arid areas in White Nile State (Sudan by using multi-temporal imagery of the Landsat satellite TM (1987, TM (2000, and ETM+ (2014 respectively. The paper also discusses and evaluates the efficiency of the adapted methodologies in monitoring the land degradation processes and changes in the arid and semi-arid regions.

DIGGING INTO NGC 6334 I(N): MULTIWAVELENGTH IMAGING OF A MASSIVE PROTOSTELLAR CLUSTER

International Nuclear Information System (INIS)

Brogan, C. L.; Hunter, T. R.; Indebetouw, R.; Cyganowski, C. J.; Beuther, H.; Menten, K. M.; Thorwirth, S.

2009-01-01

We present a high-resolution, multi-wavelength study of the massive protostellar cluster NGC 6334 I(N) that combines new spectral line data from the Submillimeter Array (SMA) and VLA with a re-analysis of archival VLA continuum data, Two Micron All Sky Survey and Spitzer images. As shown previously, the brightest 1.3 mm source SMA1 contains substructure at subarcsecond resolution, and we report the first detection of SMA1b at 3.6 cm along with a new spatial component at 7 mm (SMA1d). We find SMA1 (aggregate of sources a, b, c, and d) and SMA4 to be comprised of free-free and dust components, while SMA6 shows only dust emission. Our 1.''5 resolution 1.3 mm molecular line images reveal substantial hot-core line emission toward SMA1 and to a lesser degree SMA2. We find CH 3 OH rotation temperatures of 165 ± 9 K and 145 ± 12 K for SMA1 and SMA2, respectively. We estimate a diameter of 1400 AU for the SMA1 hot-core emission, encompassing both SMA1b and SMA1d, and speculate that these sources comprise a ∼>800 AU separation binary that may explain the previously suggested precession of the outflow emanating from the SMA1 region. Compact line emission from SMA4 is weak, and none is seen toward SMA6. The LSR velocities of SMA1, SMA2, and SMA4 all differ by 1-2 km s -1 . Outflow activity from SMA1, SMA2, SMA4, and SMA6 is observed in several molecules including SiO(5-4) and IRAC 4.5 μm emission; 24 μm emission from SMA4 is also detected. Eleven water maser groups are detected, eight of which coincide with SMA1, SMA2, SMA4, and SMA6, while two others are associated with the Sandell source SM2. We also detect a total of 83 Class I CH 3 OH 44 GHz maser spots which likely result from the combined activity of many outflows. Our observations paint the portrait of multiple young hot cores in a protocluster prior to the stage where its members become visible in the near-infrared.

Penggunaan Media Sosial Sesuai Nilai Luhur Budaya di Kalangan Siswa SMA

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Roswita Oktavianti

2017-12-01

Full Text Available The youth as a generation of social media users holds great control over the dissemination of information in groups and families. Social media like Facebook, Twitter, Instagram, Path, becomes a medium of expression and self-existence, and the spread of news and information. In this case, social media becomes a means of spreading the noble values of the culture that is acculturated in one's self and their surrounding environment. However, the younger generation is less aware of the role of social media as a means of spreading the noble values of culture. Information and news in social media are accepted immediately without verifying the truth. Social media is more dominantly used as a means of self-expression, without a positive contribution to other social media users, or, in this case, followers. Therefore, the younger generation needs to be briefed on the use of social media as well as the importance of using social media as a medium that communicates the noble values of culture. The briefing was conducted at SMA Santo Kristoforus 1, West Jakarta. By using survey method to know the effectiveness of the briefing, the younger generation' understanding of the use of social media before and after the briefing. The outcome of this activity, all students are able to show which information that should or should not be disseminated, able to recognize or identify false news (hoaxes, false news information, and the steps taken when receiving the false news.

FAKTOR DETERMINAN KEMAMPUAN PERENCANAAN KARIER SISWA SMA NEGERI SE-KABUPATEN TEGAL

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Lu'luatun Miskiya

2014-06-01

Full Text Available Tujuan penelitian ini untuk mengetahui faktor determinan kemampuan perencanaan karier siswa. Jenis penelitian adalah penelitian survey. Populasi penelitian ini yaitu siswa kelas XI SMA Negeri se-Kabupaten Tegal. Teknik sampling yang digunakan Cluster Sampling Proporsional. Metode pengumpulan data menggunakan angket tertutup. Analisis datanya menggunakan deskriptif persentase. Hasil penelitian menunjukkan faktor keluarga menjadi faktor determinan terhadap kemampuan perencanaan karier siswa dengan perolehan persentase sebesar 80% yang berada dalam kategori tinggi. Sedangkan faktor belajar menjadi faktor yang kurang determinan terhadap kemampuan perencanaan karier siswa dengan perolehan persentase sebesar 67% yang berada dalam kategori sedang. Simpulan dari penelitian ini, faktor keluarga menjadi faktor determinan terhadap kemampuan perencanaan karier siswa. The purpose of the study was to find out the determinant  factor of students career planning ability. This research was using survey research with XI grades students of State Senior High Schools in Tegal regency as the population. Proportionate cluster sampling technique was used  in this study. Method for collecting data was used close questionnaire. The data analysis used descriptive percentages.The results showed family factor become the determinant factor of students career planning ability with the percentage of 80 % which is in the high category while learning factor become less determinant factor of the ability of students career planning with a percentage of 67%  in the medium category . It can concluded that family factor become  determinant factor in the ability of students career planning.

Pengembangan Lembar Aktivitas Siswa (LAS Matematika Kelas X SMA Dengan Penerapan Variasi Model Pembelajaran Kooperatif

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Tetty Natalia Sipayung

2018-03-01

Full Text Available Abstrak. Tujuan dari penelitian ini adalah untuk mengetahui: (1 validitas Lembar Aktivitas Siswa (LAS matematika kelas X SMA yang dikembangkan dengan penerapan variasi model pembelajaran kooperatif; (2 efektivitas pembelajaran dengan menggunakan Lembar Aktivitas Siswa  matematika dengan menerapkan variasi model pembelajaran kooperatif. Adapun jenis penelitian ini adalah penelitian dan pengembangan (Research and Development yang mengembangkan bahan ajar berupa Lembar Aktivitas Siswa. Hasil dari penelitian ini adalah: (1 Lembar Aktivitas Siswa matematika kelas X SMA yang dikembangkan adalah valid dengan skor rata-rata dari validator adalah 4,56 atau 91,2%. Dikatakan valid artinya layak digunakan atau dipakai dalam pembelajaran matematika; (2 Pembelajaran dengan menggunakan Lembar Aktivitas Siswa matematika dengan menerapkan variasi model pembelajaran kooperatif adalah efektif. Hal tersebut dianalisis berdasarkan observasi aktivitas siswa, kemampuan guru dalam mengelola pembelajaran, dan hasil belajar siswa di kelas eksperimen dan di kelas kontrol. Siswa pada kelas eksperimen dibelajarkan dengan menggunakan Lembar Aktivitas Siswa (LAS dan menerapkan variasi model pembelajaran kooperatif yaitu tipe Student Teams Achievement Division (STAD, Numbered Head Together (NHT, Think Pair Share (TPS, dan Jigsaw pada kelas eksperimen. Sementara siswa pada kelas kontrol dibelajarkan tanpa menggunakan Lembar Aktivitas Siswa (LAS dan menerapkan pembelajaran konvensional. Kata Kunci: Lembar Aktivitas Siswa, Model Pembelajaran Kooperatif    Abstract. The objectives of the research are: (1 The validity of student’s Mathematic worksheet for tenth grade of senior high school using various cooperative leaning models; (2 The learning effectiveness of student’s Mathematic worksheet sheet using various cooperative learning. The method used is research and development that develops students’ Mathematic worksheet as teaching media. The research findings are as

Young Stellar Objects in the Massive Star-forming Regions W51 and W43

Energy Technology Data Exchange (ETDEWEB)

Saral, G.; Audard, M. [Department of Astronomy, University of Geneva, Ch. d’Ecogia 16, 1290 Versoix (Switzerland); Hora, J. L.; Martínez-Galarza, J. R.; Smith, H. A. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Koenig, X. P. [Yale University, Department of Astronomy, 208101, New Haven, CT 06520-8101 (United States); Motte, F. [Institut de Plantologie et d’Astrophysique de Grenoble, Univ. Grenoble Alpes—CNRS-INSU, BP 53, F-38041 Grenoble Cedex 9 (France); Nguyen-Luong, Q. [National Astronomical Observatory of Japan, Chile Observatory, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Saygac, A. T. [Istanbul University, Faculty of Science, Astronomy and Space Sciences Department, Istanbul-Turkey (Turkey)

2017-04-20

We present the results of our investigation of the star-forming complexes W51 and W43, two of the brightest in the first Galactic quadrant. In order to determine the young stellar object (YSO) populations in W51 and W43 we used color–magnitude relations based on Spitzer mid-infrared and 2MASS/UKIDSS near-infrared data. We identified 302 Class I YSOs and 1178 Class II/transition disk candidates in W51, and 917 Class I YSOs and 5187 Class II/transition disk candidates in W43. We also identified tens of groups of YSOs in both regions using the Minimal Spanning Tree (MST) method. We found similar cluster densities in both regions, even though Spitzer was not able to probe the densest part of W43. By using the Class II/I ratios, we traced the relative ages within the regions and, based on the morphology of the clusters, we argue that several sites of star formation are independent of one another in terms of their ages and physical conditions. We used spectral energy distribution-fitting to identify the massive YSO (MYSO) candidates since they play a vital role in the star formation process, and then examined them to see if they are related to any massive star formation tracers such as UCH ii regions, masers, or dense fragments. We identified 17 MYSO candidates in W51, and 14 in W43, respectively, and found that groups of YSOs hosting MYSO candidates are positionally associated with H ii regions in W51, though we do not see any MYSO candidates associated with previously identified massive dense fragments in W43.

Regional hydrogeological conceptual model of candidate Beishan area for high level radioactive waste disposal repository

International Nuclear Information System (INIS)

Wang Hailong; Guo Yonghai

2014-01-01

The numerical modeling of groundwater flow is an important aspect of hydrogeological assessment in siting of a high level radioactive waste disposal repository. Hydrogeological conceptual model is the basic and premise of numerical modeling of groundwater flow. Based on the hydrogeological analysis of candidate Beishan area, surface water system was created by using DEM data and the modeling area is determined. Three-dimensional hydrogeological structure model was created through GMS software. On the basis of analysis and description of boundary condition, flow field, groundwater budget and hydrogeological parameters, hydrogeological conceptual model was set up for the Beishan area. (authors)

Altered regional homogeneity in the development of minimal hepatic encephalopathy: a resting-state functional MRI study.

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Ling Ni

Full Text Available BACKGROUND: Little is known about how spontaneous brain activity progresses from non-hepatic encephalopathy (non-HE to minimal HE (MHE. The purpose of this study was to evaluate the evolution pattern of spontaneous brain activities in cirrhotic patients using resting-state fMRI with a regional homogeneity (ReHo method. METHODOLOGY/PRINCIPAL FINDINGS: Resting-state fMRI data were acquired in 47 cirrhotic patients (minimal HE [MHE], n = 20, and non-HE, n = 27 and 25 age-and sex-matched healthy controls. The Kendall's coefficient of concordance (KCC was used to measure the regional homogeneity. The regional homogeneity maps were compared with ANOVA tests among MHE, non-HE, and healthy control groups and t-tests between each pair in a voxel-wise way. Correlation analyses were performed to explore the relationships between regional ReHo values and Child-Pugh scores, number connection test type A (NCT-A, digit symbol test (DST scores, venous blood ammonia levels. Compared with healthy controls, both MHE and non-HE patients showed decreased ReHo in the bilateral frontal, parietal and temporal lobes and increased ReHo in the bilateral caudate. Compared with the non-HE, MHE patients showed decreased ReHo in the bilateral precuneus, cuneus and supplementary motor area (SMA. The NCT-A of cirrhotic patients negatively correlated with ReHo values in the precuneus, cuneus and lingual gyrus. DST scores positively correlated with ReHo values in the cuneus, precuneus and lingual gyrus, and negatively correlated with ReHo values in the bilateral caudate (P<0.05, AlphaSim corrected. CONCLUSIONS/SIGNIFICANCE: Diffused abnormal homogeneity of baseline brain activity was nonspecific for MHE, and only the progressively decreased ReHo in the SMA and the cuneus, especially for the latter, might be associated with the development of MHE. The ReHo analysis may be potentially valuable for detecting the development from non-HE to MHE.

Tumor location and IDH1 mutation may predict intraoperative seizures during awake craniotomy.

Science.gov (United States)

Gonen, Tal; Grossman, Rachel; Sitt, Razi; Nossek, Erez; Yanaki, Raneen; Cagnano, Emanuela; Korn, Akiva; Hayat, Daniel; Ram, Zvi

2014-11-01

Intraoperative seizures during awake craniotomy may interfere with patients' ability to cooperate throughout the procedure, and it may affect their outcome. The authors have assessed the occurrence of intraoperative seizures during awake craniotomy in regard to tumor location and the isocitrate dehydrogenase 1 (IDH1) status of the tumor. Data were collected in 137 consecutive patients who underwent awake craniotomy for removal of a brain tumor. The authors performed a retrospective analysis of the incidence of seizures based on the tumor location and its IDH1 mutation status, and then compared the groups for clinical variables and surgical outcome parameters. Tumor location was strongly associated with the occurrence of intraoperative seizures. Eleven patients (73%) with tumor located in the supplementary motor area (SMA) experienced intraoperative seizures, compared with 17 (13.9%) with tumors in the other three non-SMA brain regions (p awake craniotomy compared with patients who have a tumor in non-SMA frontal areas and other brain regions. The IDH1 mutation was more common in SMA region tumors compared with other brain regions, and may be an additional risk factor for the occurrence of intraoperative seizures.

JELLYFISH GALAXY CANDIDATES AT LOW REDSHIFT

Energy Technology Data Exchange (ETDEWEB)

Poggianti, B. M.; Fasano, G.; Omizzolo, A.; Gullieuszik, M.; Bettoni, D.; Paccagnella, A. [INAF-Astronomical Observatory of Padova (Italy); Moretti, A.; D’Onofrio, M. [Physics and Astronomy Department, University of Padova (Italy); Jaffé, Y. L. [Department of Astronomy, Universidad de Concepción, Concepción (Chile); Vulcani, B. [Kavli Institute for the Physics and Mathematics of the universe (WPI), The University of Tokyo Institutes for Advanced Study (UTIAS), the University of Tokyo, Kashiwa, 277-8582 (Japan); Fritz, J. [Centro de Radioastronomía y Astrofísica, CRyA, UNAM, Michoacán (Mexico); Couch, W. [Australian Astronomical Observatory, North Ryde, NSW 1670 (Australia)

2016-03-15

Galaxies that are being stripped of their gas can sometimes be recognized from their optical appearance. Extreme examples of stripped galaxies are the so-called “jellyfish galaxies” that exhibit tentacles of debris material with a characteristic jellyfish morphology. We have conducted the first systematic search for galaxies that are being stripped of their gas at low-z (z = 0.04−0.07) in different environments, selecting galaxies with varying degrees of morphological evidence for stripping. We have visually inspected B- and V-band images and identified 344 candidates in 71 galaxy clusters of the OMEGAWINGS+WINGS sample and 75 candidates in groups and lower mass structures in the PM2GC sample. We present the atlas of stripping candidates and a first analysis of their environment and their basic properties, such as morphologies, star formation rates and galaxy stellar masses. Candidates are found in all clusters and at all clustercentric radii, and their number does not correlate with the cluster velocity dispersion σ or X-ray luminosity L{sub X}. Interestingly, convincing cases of candidates are also found in groups and lower mass halos (10{sup 11}−10{sup 14}M{sub ⊙}), although the physical mechanism at work needs to be securely identified. All the candidates are disky, have stellar masses ranging from log M/M{sub ⊙} < 9 to > 11.5 and the majority of them form stars at a rate that is on average a factor of 2 higher (2.5σ) compared to non-stripped galaxies of similar mass. The few post-starburst and passive candidates have weak stripping evidence. We conclude that disturbed morphologies suggestive of stripping phenomena are ubiquitous in clusters and could be present even in groups and low mass halos. Further studies will reveal the physics of the gas stripping and clarify the mechanisms at work.

Scalar tetraquark candidates on the lattice

International Nuclear Information System (INIS)

Berlin, Joshua

2017-01-01

The topic of this thesis is the investigation of scalar tetraquark candidates from lattice QCD. It is motivated by a previous study originating in the twisted mass collaboration. The initial tetraquark candidate of choice is the a 0 (980), an isovector in the nonet of light scalars (J P =0 + ). This channel is still poorly understood. It displays an inverted mass hierarchy to what is expected from the conventional quark model and the a 0 (980) and f 0 (980) feature a surprising mass degeneracy. For this reasons the a 0 (980) is a long assumed tetraquark candidate in the literature. We follow a methodological approach by studying the sensitivity of the scalar spectrum with fully dynamical quarks to a large basis of two-quark and four-quark creation operators. Ultimately, the candidate has to be identified in the direct vicinity of two two-particles states, which is understandably inevitable for a tetraquark candidate. To succeed in this difficult task two-meson creation operators are essential to employ in this channel. By localized four-quark operators we intend to probe the Hamiltonian on eigenstates with a closely bound four-quark structure.

Scalar tetraquark candidates on the lattice

Energy Technology Data Exchange (ETDEWEB)

Berlin, Joshua

2017-07-01

The topic of this thesis is the investigation of scalar tetraquark candidates from lattice QCD. It is motivated by a previous study originating in the twisted mass collaboration. The initial tetraquark candidate of choice is the a{sub 0}(980), an isovector in the nonet of light scalars (J{sup P}=0{sup +}). This channel is still poorly understood. It displays an inverted mass hierarchy to what is expected from the conventional quark model and the a{sub 0}(980) and f{sub 0}(980) feature a surprising mass degeneracy. For this reasons the a{sub 0}(980) is a long assumed tetraquark candidate in the literature. We follow a methodological approach by studying the sensitivity of the scalar spectrum with fully dynamical quarks to a large basis of two-quark and four-quark creation operators. Ultimately, the candidate has to be identified in the direct vicinity of two two-particles states, which is understandably inevitable for a tetraquark candidate. To succeed in this difficult task two-meson creation operators are essential to employ in this channel. By localized four-quark operators we intend to probe the Hamiltonian on eigenstates with a closely bound four-quark structure.

Carrier screening for spinal muscular atrophy in Italian population

Indian Academy of Sciences (India)

SMA is necessary for effective clinical/prenatal diagnosis ... of SMA critical region in the group of 450 normal controls. ... izing and quality test are as described in Calì et al. .... nosis for spinal muscular atrophy: clinical laboratory analysis of.

Candidate cave entrances on Mars

Science.gov (United States)

Cushing, Glen E.

2012-01-01

This paper presents newly discovered candidate cave entrances into Martian near-surface lava tubes, volcano-tectonic fracture systems, and pit craters and describes their characteristics and exploration possibilities. These candidates are all collapse features that occur either intermittently along laterally continuous trench-like depressions or in the floors of sheer-walled atypical pit craters. As viewed from orbit, locations of most candidates are visibly consistent with known terrestrial features such as tube-fed lava flows, volcano-tectonic fractures, and pit craters, each of which forms by mechanisms that can produce caves. Although we cannot determine subsurface extents of the Martian features discussed here, some may continue unimpeded for many kilometers if terrestrial examples are indeed analogous. The features presented here were identified in images acquired by the Mars Odyssey's Thermal Emission Imaging System visible-wavelength camera, and by the Mars Reconnaissance Orbiter's Context Camera. Select candidates have since been targeted by the High-Resolution Imaging Science Experiment. Martian caves are promising potential sites for future human habitation and astrobiology investigations; understanding their characteristics is critical for long-term mission planning and for developing the necessary exploration technologies.

THE COMPARISON OF STUDENTS’ READING COMPREHENSION IN RECOUNT TEXT INSTRUCTION BETWEEN USING STAD AND JIGSAW TECHNIQUE AT DIFFERENT READING FREQUENCY AT THE FIRST GRADE OF SMA N 1 RUMBIA ACADEMIC YEAR 2012/2013

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Didik Firnadi -

2014-04-01

Full Text Available Reading as one of the four skills has always been as a part of the syllabus in English instruction. Based on the Pra survey, reading comprehension of the students of the first grade of SMA N 1 Rumbia is still low, most of them still lack structure knowledge and vocabulary, and their reading frequency in reading is still low. There are two techniques presented as a solution in this research. They are STAD Technique and Jigsaw technique. The objective of this research is to find out the difference result of using STAD and Jigsaw technique toward students’ reading comprehension in recount text at different high and low reading frequency and to find out there is significant interaction and comparison of reading comprehension in recount text, learning technique, and different reading frequency at the first grade students of SMA N 1 Rumbia academic year 2012/2013. The method of investigation is held through quantitative research. The researcher uses true experimental research. In this experiment, the the researcher applies factorials design. The research is conducted at the first grade of SMA N 1 Rumbia in academic year 2012/2013. The population in this research is 180 students. It consisted 6 classes and each class consist 30 students. The researcher takes 52 students from total population as the sample, 26 students as experiment class and 26 as control class that match based on classification of student level. The researcher uses cluster random sampling as technique sampling. To analyze data, the researcher uses ANOVA TWO WAYS formula. The researcher got the result of Fhit is 18, 2 and Ftable  is 7, 14. It means that Fhit > Ftable. And the criterion of Ftest is Ha accepted if Fhit  > Ftable. So, there is any difference result of students’ Reading comprehension in recount text using STAD and Jigsaw, and STAD technique is more effective technique than Jigsaw technique toward students Reading comprehension at different reading frequency at the

Event display of a H -> 4mu candidate event

CERN Multimedia

ATLAS, Collaboration

2012-01-01

Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Muon tracks are colored red. The inset on the right-hand side shows a zoom into the tracking detector. The inset on top shows a zoom into the vertex region, indicating that the 4 muons originate from the same primary vertex.

PENGARUH MODEL PEMBELAJARAN ADVANCE ORGANIZER BERBASIS MIND MAP TERHADAP HASIL BELAJAR FISIKA SISWA PADA MATERI POKOK BESARAN DAN SATUAN DI KELAS X SMA

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Karya Sinulingga

2012-12-01

Full Text Available Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran advance organizer berbasis mind map terhadap hasil belajar Fisika siswa. Populasi dalam penelitian ini adalah seluruh siswa kelas X SMA Negeri 5 Pematangsiantar semester I Tahun Pembelajaran 2012/2013 berjumlah 8 kelas. Pengambilan sampel dilakukan secara cluster random sampling, diambil 2 kelas yaitu kelas eksperimen diterapkan model pembelajaran advance organizer dan kelas kontrol diterapkan model pembelajaran konvensional. Berdasarkan hasil analisis data pretes diperoleh nilai rata-rata kelas eksperimen 37,25 dan kelas kontrol 36,63. Hasil uji beda nilai kedua kelas pada taraf signifikan á = 0,05 diperoleh thitung = 0,369 dan ttabel = 1,991. Dapat disimpulkan tidak terdapat perbedaan yang signifikan nilai pretes kedua kelas, artinya kedua kelas memiliki kemampuan awal yang sama. Selanjutnya dilakukan pembelajaran dengan model pembelajaran advance organizer berbasis mind map pada kelas eksperimen dan pembelajaran konvensional pada kelas kontrol. Setelah pembelajaran diberikan kemudian pada kedua kelas dilakukan postes. Untuk kelas eksperimen diperoleh nilai rata-rata 72,50 dan untuk kelas kontrol diperoleh 60,63. Hasil pengujian hipotesis dengan taraf signifikan 0,05 diperoleh hitung t = 4,479 dan tabel t = 1,666. Karena hitung t > tabel t maka hipotesis (Ha diterima, sehingga dapat disimpulkan terdapat pengaruh model pembelajaran advance organizer berbasis mind map terhadap hasil belajar siswa pada materi pokok besaran Fisika dan satuannya di kelas X semester I SMA Negeri 5 Pematangsiantar T.P 2012/2013.

A New Way to Confirm Planet Candidates

Science.gov (United States)

Kohler, Susanna

2016-05-01

What was the big deal behind the Kepler news conference yesterday? Its not just that the number of confirmed planets found by Kepler has more than doubled (though thats certainly exciting news!). Whats especially interesting is the way in which these new planets were confirmed.Number of planet discoveries by year since 1995, including previous non-Kepler discoveries (blue), previous Kepler discoveries (light blue) and the newly validated Kepler planets (orange). [NASA Ames/W. Stenzel; Princeton University/T. Morton]No Need for Follow-UpBefore Kepler, the way we confirmed planet candidates was with follow-up observations. The candidate could be validated either by directly imaging (which is rare) or obtaining a large number radial-velocity measurements of the wobble of the planets host star due to the planets orbit. But once Kepler started producing planet candidates, these approaches to validation became less feasible. A lot of Kepler candidates are small and orbit faint stars, making follow-up observations difficult or impossible.This problem is what inspired the development of whats known as probabilistic validation, an analysis technique that involves assessing the likelihood that the candidates signal is caused by various false-positive scenarios. Using this technique allows astronomers to estimate the likelihood of a candidate signal being a true planet detection; if that likelihood is high enough, the planet candidate can be confirmed without the need for follow-up observations.A breakdown of the catalog of Kepler Objects of Interest. Just over half had previously been identified as false positives or confirmed as candidates. 1284 are newly validated, and another 455 have FPP of1090%. [Morton et al. 2016]Probabilistic validation has been used in the past to confirm individual planet candidates in Kepler data, but now Timothy Morton (Princeton University) and collaborators have taken this to a new level: they developed the first code thats designed to do fully

Ranking candidate disease genes from gene expression and protein interaction: a Katz-centrality based approach.

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Jing Zhao

Full Text Available Many diseases have complex genetic causes, where a set of alleles can affect the propensity of getting the disease. The identification of such disease genes is important to understand the mechanistic and evolutionary aspects of pathogenesis, improve diagnosis and treatment of the disease, and aid in drug discovery. Current genetic studies typically identify chromosomal regions associated specific diseases. But picking out an unknown disease gene from hundreds of candidates located on the same genomic interval is still challenging. In this study, we propose an approach to prioritize candidate genes by integrating data of gene expression level, protein-protein interaction strength and known disease genes. Our method is based only on two, simple, biologically motivated assumptions--that a gene is a good disease-gene candidate if it is differentially expressed in cases and controls, or that it is close to other disease-gene candidates in its protein interaction network. We tested our method on 40 diseases in 58 gene expression datasets of the NCBI Gene Expression Omnibus database. On these datasets our method is able to predict unknown disease genes as well as identifying pleiotropic genes involved in the physiological cellular processes of many diseases. Our study not only provides an effective algorithm for prioritizing candidate disease genes but is also a way to discover phenotypic interdependency, cooccurrence and shared pathophysiology between different disorders.

76 FR 36130 - Call for Candidates

Science.gov (United States)

2011-06-21

... financial information in decision-making. The Board meets in Washington, DC, for two days every other month... FEDERAL ACCOUNTING STANDARDS ADVISORY BOARD Call for Candidates AGENCY: Federal Accounting... candidates. Any applicant who provided the Federal Accounting Standards Advisory Board (FASAB or the Board...

TEACHING DESCRIPTIVE READING BY USING SURVEY, QUESTION, READ, WRITE AND (SQRW STRATEGY TO THE TENTH GRADE STUDENTS OF SMA MUHAMMADIYAH 1 PALEMBANG

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marlen rahmawati

2017-05-01

Full Text Available The objectives of this study are to find out whether or not there is a significant improvement before and after the treatment on the tenth grade students’ reading comprehension scores of SMA Muhammadiyah 1 Palembang by using SQRW strategy and to find out whether or not there is a significant difference on the tenth grade students’ reading comprehension scores of SMA Muhammadiyah 1 Palembang between the students who are taught by using SQRW strategy and those who are not. This study used quasi-experimental design using nonequivalent pretest-posttest design. There were 68 students from class X MIPA 4 and X MIPA 6 chosen as the sample. In collecting the data, test was used. The test was given twice to experimental and control groups, for pretest and posttest. To verify the hypotheses, the data of pretest and posttest were analyzed by using independent sample t-test and paired sample t-test in SPSS 18 program. The findings showed that the p-output from paired sample t-test (sig2-tailed was 0.000 which was lower than 0.05, and t-value 11.294 was higher than t-table (34-1 with df=33 (2.034. The result of p-output from independent sample t-test was 0.003 which was lower that 0.05 and the t-value 3.104 was higher than t-table (68-2 with df=66 (1.996. Therefore it could be stated that teaching reading descriptive text by using SQRW strategy had significant improvement and showed significant difference on the students’ reading comprehension scores.

Evaluation of Permanent Deformation of Unmodified and Rubber-Reinforced SMA Asphalt Mixtures Using Dynamic Creep Test

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Herda Yati Katman

2015-01-01

Full Text Available This paper presents the evaluation of permanent deformation of rubber-reinforced SMA asphalt mixtures by using dynamic creep test. The effect of trans-polyoctenamer as a cross-linking agent in permanent deformation of rubberized mixtures was also evaluated. Dynamic creep test was conducted at different stress levels (200 kPa, 400 kPa and temperatures (40°C, 50°C. Permanent deformation parameters such as dynamic creep curve, ultimate strain, and creep strain slope (CSS were used to analyse the results. Finally, the creep behaviour of the specimens was estimated by the Zhou three-stage creep model. The results show that crumb rubber and trans-polyoctenamer significantly affected the parameters especially at high stress and temperatures. Consistent findings were observed for all permanent deformation parameters. Moreover, based on Zhou model, it was concluded that resistance to permanent deformation was improved by application of crumb rubber and trans-polyoctenamer.

Calibration of SMA material model for the prediction of the ‘evolutionary’ load-bias behavior under conditions of extended thermal cycling

International Nuclear Information System (INIS)

Saleeb, A F; Dhakal, B; Padula II, S A; Gaydosh, D J

2013-01-01

This work is focused on the characterization of the cyclic response of the 55NiTi polycrystalline material system using a recently formulated, multimechanism-based, modeling framework. It has a number of significant contributions. First, it presents a comprehensive characterization of such a complex material system under broad thermo-mechanical loading conditions in isobaric experiments that cover: (a) the entire relevant stress range from 10 to 300 MPa, and (b) sufficient number of thermal cycles to enable the investigation of the details of the evolution of the cyclic strain-versus-temperature hysteresis loops. Second, the detailed comparisons presented for the model results and the experimental measurements provide the necessary validation of the modeling capabilities of the multimechanism framework. Third, specific plots are given detailing the variations with thermal cycling of the internal variables associated with each of the individual inelastic mechanisms. Fourth, an anatomical discussion details the interplay between the internal mechanisms to describe the material behavior within all the important response characteristic regions, thus providing a convenient means to complement the theoretical concepts in the mathematical approach. Given the comprehensive nature of this model, and its successful experimental validation under a wide range of conditions, it is believed that the model is capable of analyzing 55NiTi actuators. It is also emphasized that the insights provided in this work will carry forth to characterization of other SMA material systems. (paper)

CANDIDATE GENE ANALYSIS IN ISRAELI SOLDIERS WITH STRESS FRACTURES

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Ran Yanovich

2012-03-01

Full Text Available To investigate the association of polymorphisms within candidate genes which we hypothesized may contribute to stress fracture predisposition, a case-control, cross- sectional study design was employed. Genotyping 268 Single Nucleotide Polymorphisms- SNPs within 17 genes in 385 Israeli young male and female recruits (182 with and 203 without stress fractures. Twenty-five polymorphisms within 9 genes (NR3C1, ANKH, VDR, ROR2, CALCR, IL6, COL1A2, CBG, and LRP4 showed statistically significant differences (p < 0.05 in the distribution between stress fracture cases and non stress fracture controls. Seventeen genetic variants were associated with an increased stress fracture risk, and eight variants with a decreased stress fracture risk. None of the SNP associations remained significant after correcting for multiple comparisons (false discovery rate- FDR. Our findings suggest that genes may be involved in stress fracture pathogenesis. Specifically, the CALCR and the VDR genes are intriguing candidates. The putative involvement of these genes in stress fracture predisposition requires analysis of more cases and controls and sequencing the relevant genomic regions, in order to define the specific gene mutations

Decreased regional cerebral glucose metabolism in the prefrontal regions in adults' with internet game addiction

International Nuclear Information System (INIS)

Park, Hyun Soo; Bang, Soong Ae; Yoon, Eun Jin; Cho, Sang Soo; Kim, Sang Hee; Kim, Yu Kyeong; Kim, Sang Eun

2007-01-01

Internet Game Addiction (IGA) is known to be associated with poor decision-making and diminished impulse control; however, the underlying neural substrates of IGA have not been identified. To investigate the neural substrates of IGA, we compared regional cerebral glucose metabolism between adults with and without IGA, primarily in the prefrontal brain regions, which have been implicated in inhibitory control. We studied 10 right-handed participants (5 controls: male, 23.8±0.75 y, 5 IGAs: male, 22.6±2.42 y) with FDG PET. A standardized questionnaire was used to assess the severity of IGA. Before scanning, all subjects carried out a computerized version of the Iowa Gambling Task (IGT) and the Balloon Analogue Risk Task (BART), as measures of behavioral inhibitory control. Statistical Parametric Mapping 2 (SPM2) was used to analyze differences in regional brain glucose metabolism between adults with and without IGA. Consistent with our predictions, compared to controls, significant reductions in FDG uptake in individuals with IGA were found in the bilateral orbitofrontal gyrus (BA 11, 47), bilateral inferior frontal gyrus (BA 44, 48), cingulate cortex (BA 24), and bilateral supplementary motor area (SMA) (BA 6); whereas increases were found in the bilateral hippocampus. Correlation analyses within the IGA group further showed that the level of glucose metabolism in the right orbitofrontal gyrus was marginally positively correlated with task scores in BART. Our results showed that IGA is associated with reduced glucose metabolism in the prefrontal regions involved in inhibitory control. This finding highlights dysfunctional inhibitory brain systems in individuals with IGA and offers implications for the development for therapeutic paradigms for IGA

Electoral Competition when Candidates are Better Informed than Voters

DEFF Research Database (Denmark)

Jensen, Thomas

candidates are both completely office-motivated but differ in state-dependent quality. Voters have some information about the state but candidates are better informed. If voters' information is unknown to the candidates when they take positions and sufficiently accurate then candidates will, in refined...

Inovasi Pembelajaran Pendidikan Agama Islam melalui E-Learning di SMA Budaya Bandar Lampung

Directory of Open Access Journals (Sweden)

Nur Asiah

2016-07-01

Full Text Available Learning is the totality of learning activity that begins with planning and ending with the evaluation and follow-up. Developments in science followed by the development of internet information technology and leading edge technology. With the innovation of education, the learning process can be developed and improved the quality of the quality of information technology, better known as e-learning. E-learning is a new learning model in the educational use of information technology in teaching and learning. Problems faced by the schools and teachers is the ability to apply e-learning, self-learning culture is lacking, teachers who have not been able to use and develop learning e-learning and Internet network system that can not be accessed. Data collection techniques used in this study was the observation, interview and documentation. Implementation of e-learning often contentious among high schools Cultural Bandar Lampung. In the process of learning in e-learning, an innovation and interaction between learners with learning resources, between teachers and learners. Innovation PAI learning via e-learning can be divided into two namely, a e-learning is used entirely for learning PAI in SMA Culture Bandar Lampung, b Learning e-learning at the School of Culture serve as a complement to conventional learning.

Spatially Resolved Imaging and Spectroscopy of Candidate Dual Active Galactic Nuclei

Science.gov (United States)

McGurk, R. C.; Max, C. E.; Medling, A. M.; Shields, G. A.; Comerford, J. M.

2015-09-01

When galaxies merge, both central supermassive black holes are immersed in a dense and chaotic environment. If there is sufficient gas in the nuclear regions, one expects to see close pairs of active galactic nuclei (AGNs), or dual AGNs, in a fraction of galaxy mergers. However, finding them remains a challenge. The presence of double-peaked [O iii] emission lines has been proposed as a technique to select dual AGNs efficiently. We studied a sample of double-peaked narrow [O iii] emitting AGNs from Sloan Digital Sky Survey (SDSS) DR7. By obtaining new and archival high spatial resolution images taken with the Keck II Laser Guide Star Adaptive Optics system and the near-infrared camera NIRC2, we show that 30% of 140 double-peaked [O iii] emission line SDSS AGNs have two spatial components within a 3″ radius. However, spatially resolved spectroscopy or X-ray observations are needed to confirm these galaxy pairs as systems containing two AGNs. We followed up three spatially double candidate dual AGNs with integral field spectroscopy from Keck OSIRIS and 10 candidates with long-slit spectroscopy from the Shane Kast Double Spectrograph at Lick Observatory. We find that the double-peaked emission lines in our sample of 12 candidates are caused by: one dual AGN (SDSS J114642.47+511029.6), one confirmed outflow and four likely outflows, two pairs of star-forming galaxies, one candidate indeterminate due to sky line interference, and three AGNs with spatially coincident double [O iii] peaks, likely due to unresolved complex narrow line kinematics, outflows, binary AGN, or small-scale jets.

SPATIALLY RESOLVED IMAGING AND SPECTROSCOPY OF CANDIDATE DUAL ACTIVE GALACTIC NUCLEI

Energy Technology Data Exchange (ETDEWEB)

McGurk, R. C.; Max, C. E. [Astronomy Department and UCO-Lick Observatory, University of California, Santa Cruz, CA 95064 (United States); Medling, A. M. [Research School of Astronomy and Astrophysics, Australian National University, Mount Stromlo Observatory, Cotter Road, Weston Creek, ACT 2611 (Australia); Shields, G. A. [Laguna Falls Institute for Astrophysics, Austin, TX 78746 (United States); Comerford, J. M., E-mail: rosalie.mcgurk@gmail.com, E-mail: max@ucolick.org, E-mail: anne.medling@anu.edu.au, E-mail: shields@lfastro.org, E-mail: julie.comerford@colorado.edu [Department of Astrophysical and Planetary Sciences, University of Colorado, Boulder, CO 80309 (United States)

2015-09-20

When galaxies merge, both central supermassive black holes are immersed in a dense and chaotic environment. If there is sufficient gas in the nuclear regions, one expects to see close pairs of active galactic nuclei (AGNs), or dual AGNs, in a fraction of galaxy mergers. However, finding them remains a challenge. The presence of double-peaked [O iii] emission lines has been proposed as a technique to select dual AGNs efficiently. We studied a sample of double-peaked narrow [O iii] emitting AGNs from Sloan Digital Sky Survey (SDSS) DR7. By obtaining new and archival high spatial resolution images taken with the Keck II Laser Guide Star Adaptive Optics system and the near-infrared camera NIRC2, we show that 30% of 140 double-peaked [O iii] emission line SDSS AGNs have two spatial components within a 3″ radius. However, spatially resolved spectroscopy or X-ray observations are needed to confirm these galaxy pairs as systems containing two AGNs. We followed up three spatially double candidate dual AGNs with integral field spectroscopy from Keck OSIRIS and 10 candidates with long-slit spectroscopy from the Shane Kast Double Spectrograph at Lick Observatory. We find that the double-peaked emission lines in our sample of 12 candidates are caused by: one dual AGN (SDSS J114642.47+511029.6), one confirmed outflow and four likely outflows, two pairs of star-forming galaxies, one candidate indeterminate due to sky line interference, and three AGNs with spatially coincident double [O iii] peaks, likely due to unresolved complex narrow line kinematics, outflows, binary AGN, or small-scale jets.

SPATIALLY RESOLVED IMAGING AND SPECTROSCOPY OF CANDIDATE DUAL ACTIVE GALACTIC NUCLEI

International Nuclear Information System (INIS)

McGurk, R. C.; Max, C. E.; Medling, A. M.; Shields, G. A.; Comerford, J. M.

2015-01-01

When galaxies merge, both central supermassive black holes are immersed in a dense and chaotic environment. If there is sufficient gas in the nuclear regions, one expects to see close pairs of active galactic nuclei (AGNs), or dual AGNs, in a fraction of galaxy mergers. However, finding them remains a challenge. The presence of double-peaked [O iii] emission lines has been proposed as a technique to select dual AGNs efficiently. We studied a sample of double-peaked narrow [O iii] emitting AGNs from Sloan Digital Sky Survey (SDSS) DR7. By obtaining new and archival high spatial resolution images taken with the Keck II Laser Guide Star Adaptive Optics system and the near-infrared camera NIRC2, we show that 30% of 140 double-peaked [O iii] emission line SDSS AGNs have two spatial components within a 3″ radius. However, spatially resolved spectroscopy or X-ray observations are needed to confirm these galaxy pairs as systems containing two AGNs. We followed up three spatially double candidate dual AGNs with integral field spectroscopy from Keck OSIRIS and 10 candidates with long-slit spectroscopy from the Shane Kast Double Spectrograph at Lick Observatory. We find that the double-peaked emission lines in our sample of 12 candidates are caused by: one dual AGN (SDSS J114642.47+511029.6), one confirmed outflow and four likely outflows, two pairs of star-forming galaxies, one candidate indeterminate due to sky line interference, and three AGNs with spatially coincident double [O iii] peaks, likely due to unresolved complex narrow line kinematics, outflows, binary AGN, or small-scale jets

Upaya Guru Bimbingan dan Konseling dalam Mencegah Perilaku Bullying di SMA Negeri Se Kota Padang

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Riri Yunika

2013-09-01

Full Text Available Bullying is a behavior consciously done by someone to abuse and hurt others. Ideally, the guidance and counseling teachers (BK teachersare demanded to give attentions in preventing bullying behavior. However, in fact, the BK teachers have not plan special programs yet to prevent the bullying behavior among students in school. This research aims to describe the understanding of BK teachers about the concept of bullying behavior. Then, it aims to describe the treatment of the BK given by the teachers to the students. Finally, it aims to describe the cooperation among the BK teachers within the school. This research is kind of descriptive research. The population of this research is all of the BK teachers of SMA Negeri (State school for secondary education in Padang. Sample is taken by using area sampling and simple random sampling techniques. Generally, the result implicates that the BK teachers have done preventing efforts toward bullying behavior among students in the school. Thus, the teachers should increase the understanding in reference to bullying behavior among students to prevent the behavior in school.

PENYELENGGARAAN MAKANAN, DAYA TERIMA MAKANAN, DAN TINGKAT ASUPAN SISWA ASRAMA KELAS UNGGULAN SMA 1 PEMALI BANGKA BELITUNG

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. Sutyawan

2014-05-01

Full Text Available ABSTRACTThe objectives of this study were to assess food service management, food acceptance, and the consumption’s level of students boarding school dormitory SMA 1 Pemali Bangka Belitung. The research was conducted in May—July 2013 with a cross sectional design. Subjects were purposively chosen with the total of 71 students. As many as 51.0% of components of food service management system have already been applied consisted of planning, purchasing, storage, processing, serving, personal hygiene, and sanitation. Spearman correlation analysis showed that the preference level for taste of food was significantly associated with energy and protein sufficiency level (p<0.05. The preference level for temperature of food was significantly associated with sufficiency levels of phosphorus (p<0.05. Preference level for temperature of food was significantly associated with compliance level of energy and iron (p<0.05. The level of compliance was significantly associated with sufficiency level of energy, iron, phosphorus, and zinc (p<0.05. Energy, protein, fosfor, iron intake from dormitory was significantly negatively associated with intake from non dormitory (p<0.05.Keywords: compliance level, food service management, preference level, sufficiency levelABSTRAKTujuan penelitian ini untuk mengetahui proses penyelenggaraan makanan, daya terima makanan, dan tingkat asupan siswa asrama kelas unggulan SMA 1 Pemali Bangka Belitung. Penelitian ini dilaksanakan pada bulan Mei hingga Juli 2013 dengan menggunakan desain cross-sectional. Subjek diambil secara purposive dengan total 71 siswa. Sebanyak 51.0% komponen sistem penyelenggaraan makanan sudah diterapkan yang terdiri dari perencanaan, pembelian, penyimpanan, pengolahan, penyajian, higiene perorangan, dan sanitasi. Uji korelasi Spearman menunjukkan bahwa tingkat kesukaan terhadap rasa makanan memiliki hubungan yang nyata dengan tingkat kecukupan energi dan protein (p<0.05. Tingkat kesukaan terhadap suhu

KEMAMPUAN BERPIKIR TINGKAT TINGGI SISWA KELAS XI DALAM PEMBELAJARAN TRIGONOMETRI BERBASIS MASALAH DI SMA NEGERI 18 PALEMBANG

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Etika Prasetyani

2016-10-01

Full Text Available Penelitian ini bertujuan untuk mendeskripsikan tentang kemampuan berpikir tingkat tinggi siswa pada pembelajaran matematika berbasis masalah. Penelitian ini merupakan jenis penelitian deskriptif dengan subjek penelitian yaitu siswa kelas XI MIPA 1 SMA Negeri 18 Palembang yang berjumlah 30 orang. Proses pembelajaran berlangsung sesuai dengan karakteristik dan langkah-langkah pembelajaran berbasis masalah. Teknik pengumpulan data yang digunakan adalah tes tertulis yang terdiri atas tiga soal dan wawancara untuk memperoleh data tambahan. Berdasarkan hasil penelitian, diperoleh hasil kemampuan berpikir tingkat tinggi siswa dalam pembelajaran matematika berbasis masalah di kelas XI MIPA 1 SMAN 18 Palembang adalah terkategori cukup dengan rincian sebagai berikut: persentase siswa yang memiliki kemampuan berpikir tingkat tinggi sangat baik adalah sebesar 16,667%. Selanjutnya, 26,667% memiliki kemampuan berpikir tingkat tinggi dengan kategori baik; 30,000% memiliki kemampuan berpikir tingkat tinggi terkategori cukup; 26,667% memiliki kemampuan berpikir tingkat tinggi terkategori kurang; dan tidak ada yang memiliki kemampuan berpikir tingkat tinggi dengan kategori sangat kurang. Indikator menganalisis memiliki persentase kemunculan tertinggi yaitu sebesar 72,500%. Kemudian, kemunculan pada indikator mengevaluasi adalah sebesar 70,000%, dan indikator dengan persentase kemunculan terendah adalah mengkreasi yaitu sebesar 35,417%. Kata kunci: kemampuan berpikir tingkat tinggi, pembelajaran trigonometri, berbasis masalah This study is descriptive research aiming to describe students higher order thinking skills in mathematics problem-based learning. Total of 30 students of class XI Mathematics 1 SMA Negeri 18 Palembang were selected as research subjects. The learning process was done in accordance with the characteristics and steps of problem-based learning. Data were collected through written test consisting of three questions and interviews to obtain

Regional siting survey for thermal power plants in the state of Ohio

International Nuclear Information System (INIS)

Elkins, M.L.; DiNunno, J.J.

1975-01-01

The selection and evaluation of sites for power plants have become increasingly difficult in recent years as pressures from various societal segments have resulted in government restraints on selection and burning of fossil fuels, on methods of heat dissipation, on acquisition of transmission line rights-of-way, and on environmental impact in general. The key elements in successful application of power plant siting technology are the development of the proper balance among the basic siting considerations and the understanding that level of detail in a study varies in an inverse relationship with the siting area under examination. As the first step in the process of selection and eventual licensing of new thermal power plant sites for a utility in the State of Ohio, the entire state was screened to determine promising candidate regions large enough to offer several possible candidate sites for thermal power plants. Because of the size of the area under consideration and the advantages of developing sites with an ultimate capacity for more than one power plant, sites with an installed capacity of 1100 to 4400 MW(e) were considered for this study. As a result of the preliminary screening conducted in four distinct steps, three candidate regions showed the best overall promise for either nuclear or fossil-fueled power plant development. Tentative identification was made of candidate sites within these candidate regions, and follow-on studies conducted in an increasing level of detail are presently in progress to determine the candidate site(s) most promising for power plant siting. (U.S.)

11 CFR 110.13 - Candidate debates.

Science.gov (United States)

2010-01-01

... debates include at least two candidates; and (2) The staging organization(s) does not structure the... PROHIBITIONS § 110.13 Candidate debates. (a) Staging organizations. (1) Nonprofit organizations described in 26..., subparts D and E. (b) Debate structure. The structure of debates staged in accordance with this section and...

PENGARUH PERSEPSI SISWA MENGENAI KEPEMIMPINAN DAN KEMAMPUAN BERKOMUNIKASI GURU TERHADAP MOTIVASI BELAJAR SISWA PADA MATA PELAJARAN EKONOMI KELAS XI-IPS SMA NEGERI 1 SAYUNG TAHUN AJARAN 2013/2014

Directory of Open Access Journals (Sweden)

Rizki Nugrahani

2014-11-01

Full Text Available Motivasi belajar merupakan segala sesuatu yang dapat memotivasi siswa atau individu untuk belajar. Hasil observasi awal menunjukkan masih banyak siswa yang memiliki motivasi belajar rendah. Tujuan penelitian ini adalah untuk mengetahui pengaruh persepsi siswa mengenai kepemimpinan dan kemampuan berkomunikasi guru terhadap motivasi belajar siswa pada mata pelajaran ekonomi kelas XI-IPS SMA Negeri 1 Sayung Tahun Ajaran 2013/2014. Populasi seluruh siswa kelas XI-IPS SMA Negeri 1 Sayung Tahun Ajaran 2013/2014 berjumlah 50 siswa, seluruhnya dijadikan responden. Teknik pengumpulan data menggunakan angket. Metode analisis data yang digunakan adalah teknik analisis deskriptif dan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa persepsi siswa mengenai kepemimpinan dan kemampuan berkomunikasi guru secara simultan berpengaruh terhadap motivasi belajar siswa pada mata pelajaran ekonomi (65%. Secara parsial persepsi siswa mengenai kepemimpinan guru berpengaruh terhadap motivasi belajar siswa pada mata pelajaran ekonomi (38,2%. Sedangkan persepsi siswa mengenai kemampuan berkomunikasi guru berpengaruh (33,8% terhadap motivasi belajar siswa pada mata pelajaran ekonomi. Motivation to learn is everything that can motivate students or individuals to learn. The results of preliminary observations indicate there are still many students who have alow learning motivation. The purpose of this study was to determine the effect of students perceptions about leadership and communication skills of teachers to students motivation on economic subjects in class XI Social SMA Negeri 1 Sayung school year 2013/2014. The population in this study are all students of class XI Social SMAN 1 Sayung school year 2013/2014 amounted to 50 students, and they are the respondent. The technique of collecting data using questionnaires. Data analysis method used is deskripstif analysis technique and multiple regression linier analysis. The results showed that the students

Candidate marketing takes the guessing game out of choosing employers.

Science.gov (United States)

Russell, Judith; Havel, Stacey

2010-01-01

Candidate marketing builds a foundation for relationships between employers and potential employees. Additionally, candidate marketing differentiates organizations in the marketplace. Organizations using candidate marketing to communicate the employer brand can expect a higher quality of candidates, and new employees are better prepared for the work environment and culture. Today, organizations can use a variety of integrated tools and techniques to communicate and build relationships with candidates. Candidate marketing demonstrates an organization's willingness towards transparency, and ability to invite open conversations between candidates and members of the organizations.

Relationship between candidate communication ability and oral certification examination scores.

Science.gov (United States)

Lunz, Mary E; Bashook, Philip G

2008-12-01

Structured case-based oral examinations are widely used in medical certifying examinations in the USA. These orals assess the candidate's decision-making skills using real or realistic patient cases. Frequently mentioned but not empirically evaluated is the potential bias introduced by the candidate's communication ability. This study aimed to assess the relationship between candidate communication ability and medical certification oral examination scores. Non-doctor communication observers rated a random sample of 90 candidates on communication ability during a medical oral certification examination. The multi-facet Rasch model was used to analyse the communication survey and the oral examination data. The multi-facet model accounts for observer and examiner severity bias. anova was used to measure differences in communication ability between passing and failing candidates and candidates grouped by level of communication ability. Pearson's correlations were used to compare candidate communication ability and oral certification examination performance. Candidate separation reliability values for the communication survey and the oral examination were 0.85 and 0.97, respectively, suggesting accurate candidate measurement. The correlation between communication scores and oral examination scores was 0.10. No significant difference was found between passing and failing candidates for measured communication ability. When candidates were grouped by high, moderate and low communication ability, there was no significant difference in their oral certification examination performance. Candidates' communication ability has little relationship to candidate performance on high-stakes, case-based oral examinations. Examiners for this certifying examination focused on assessing candidate decision-making ability and were not influenced by candidate communication ability.

Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes.

Science.gov (United States)

Ingham, Victoria A; Jones, Christopher M; Pignatelli, Patricia; Balabanidou, Vasileia; Vontas, John; Wagstaff, Simon C; Moore, Jonathan D; Ranson, Hilary

2014-11-25

The elevated expression of enzymes with insecticide metabolism activity can lead to high levels of insecticide resistance in the malaria vector, Anopheles gambiae. In this study, adult female mosquitoes from an insecticide susceptible and resistant strain were dissected into four different body parts. RNA from each of these samples was used in microarray analysis to determine the enrichment patterns of the key detoxification gene families within the mosquito and to identify additional candidate insecticide resistance genes that may have been overlooked in previous experiments on whole organisms. A general enrichment in the transcription of genes from the four major detoxification gene families (carboxylesterases, glutathione transferases, UDP glucornyltransferases and cytochrome P450s) was observed in the midgut and malpighian tubules. Yet the subset of P450 genes that have previously been implicated in insecticide resistance in An gambiae, show a surprisingly varied profile of tissue enrichment, confirmed by qPCR and, for three candidates, by immunostaining. A stringent selection process was used to define a list of 105 genes that are significantly (p ≤0.001) over expressed in body parts from the resistant versus susceptible strain. Over half of these, including all the cytochrome P450s on this list, were identified in previous whole organism comparisons between the strains, but several new candidates were detected, notably from comparisons of the transcriptomes from dissected abdomen integuments. The use of RNA extracted from the whole organism to identify candidate insecticide resistance genes has a risk of missing candidates if key genes responsible for the phenotype have restricted expression within the body and/or are over expression only in certain tissues. However, as transcription of genes implicated in metabolic resistance to insecticides is not enriched in any one single organ, comparison of the transcriptome of individual dissected body parts cannot

Evaluating historical candidate genes for schizophrenia

DEFF Research Database (Denmark)

Farrell, M S; Werge, T; Sklar, P

2015-01-01

Prior to the genome-wide association era, candidate gene studies were a major approach in schizophrenia genetics. In this invited review, we consider the current status of 25 historical candidate genes for schizophrenia (for example, COMT, DISC1, DTNBP1 and NRG1). The initial study for 24 of thes...

Efficacy of chimeric Pestivirus vaccine candidates against classical swine fever: protection and DIVA characteristics.

Science.gov (United States)

Eblé, P L; Geurts, Y; Quak, S; Moonen-Leusen, H W; Blome, S; Hofmann, M A; Koenen, F; Beer, M; Loeffen, W L A

2013-03-23

Currently no live DIVA (Differentiating Infected from Vaccinated Animals) vaccines against classical swine fever (CSF) are available. The aim of this study was to investigate whether chimeric pestivirus vaccine candidates (CP7_E2alf, Flc11 and Flc9) are able to protect pigs against clinical signs, and to reduce virus shedding and virus transmission, after a challenge with CSF virus (CSFV), 7 or 14 days after a single intramuscular vaccination. In these vaccine candidates, either the E2 or the E(rns) encoding genome region of a bovine viral diarrhoea virus strain were combined with a cDNA copy of CSFV or vice versa. Furthermore, currently available serological DIVA tests were evaluated. The vaccine candidates were compared to the C-strain. All vaccine candidates protected against clinical signs. No transmission to contact pigs was detected in the groups vaccinated with C-strain, CP7_E2alf and Flc11. Limited transmission occurred in the groups vaccinated with Flc9. All vaccine candidates would be suitable to stop on-going transmission of CSFV. For Flc11, no reliable differentiation was possible with the current E(rns)-based DIVA test. For CP7_E2alf, the distribution of the inhibition percentages was such that up to 5% false positive results may be obtained in a large vaccinated population. For Flc9 vaccinated pigs, the E2 ELISA performed very well, with an expected 0.04% false positive results in a large vaccinated population. Both CP7_E2alf and Flc9 are promising candidates to be used as live attenuated marker vaccines against CSF, with protection the best feature of CP7_E2alf, and the DIVA principle the best feature of Flc9. Copyright © 2012 Elsevier B.V. All rights reserved.

Probing molecular interactions of poly(styrene-co-maleic acid) with lipid matrix models to interpret the therapeutic potential of the co-polymer.

Science.gov (United States)

Banerjee, Shubhadeep; Pal, Tapan K; Guha, Sujoy K

2012-03-01

To understand and maximize the therapeutic potential of poly(styrene-co-maleic acid) (SMA), a synthetic, pharmacologically-active co-polymer, its effect on conformation, phase behavior and stability of lipid matrix models of cell membranes were investigated. The modes of interaction between SMA and lipid molecules were also studied. While, attenuated total reflection-Fourier-transform infrared (ATR-FTIR) and static (31)P nuclear magnetic resonance (NMR) experiments detected SMA-induced conformational changes in the headgroup region, differential scanning calorimetry (DSC) studies revealed thermotropic phase behavior changes of the membranes. (1)H NMR results indicated weak immobilization of SMA within the bilayers. Molecular interpretation of the results indicated the role of hydrogen-bond formation and hydrophobic forces between SMA and zwitterionic phospholipid bilayers. The extent of membrane fluidization and generation of isotropic phases were affected by the surface charge of the liposomes, and hence suggested the role of electrostatic interactions between SMA and charged lipid headgroups. SMA was thus found to directly affect the structural integrity of model membranes. Copyright © 2011 Elsevier B.V. All rights reserved.

Stenting of the Superior Mesenteric Artery as a Preoperative Treatment for Total Pancreatectomy

International Nuclear Information System (INIS)

Tanigawa, Noboru; Kariya, Shuji; Komemushi, Atsushi; Satoi, Sohei; Kamiyama, Yasuo; Sawada, Satoshi; Kojima, Hiroyuki; Sougawa, Mitsuharu; Takai, Yuichirou

2004-01-01

The patient was a 58-year-old male with mucinous cyst adenocarcinoma of the pancreas. Prior to total pancreatectomy, preoperative CT and angiography showed a high-grade arteriosclerotic stenosis of about 1.0 cm in length in the ostium of the superior mesenteric artery (SMA), as well as the development of collateral vessels in the area around the head of the pancreas. A stent was placed in the SMA stenosis to preserve the intestinal blood flow in the SMA region after total pancreatectomy, which was performed 25 days after stent placement. The postoperative SMA blood flow was favorable, with no postoperative intestinal ischemia, and the patient had an uneventful postoperative course

Pengembangan Buku Pengayaan “Kajian Fisis Peristiwa Angin Puting Beliung” untuk Siswa SMA

Directory of Open Access Journals (Sweden)

Desnita Desnita

2016-12-01

  dilakukan yaitu survei di delapan SMA, dua toko buku terkenal di Jakarta, toko buku online, dan Pusat Kurikulum dan Perbukuan (Puskurbuk. Hasil survei menunjukkan sajian buku pengayaan terkait angin puting beliung yang ada lebih fokus pada bencana sehingga kurang ilmiah dan kurang mendalam karena hanya sebatas dalam satu subbab. Mengacu pada hasil survei dan standar kualitas buku pengayaan, ditulis buku pengayaan pengetahuan yang membahas besaran fisis aliran gas terutama gradien tekanan, peristiwa dan konsep fisis terjadinya angin puting beliung, hingga mitigasi bencana. Berdasarkan hasil uji keterbacaan kepada siswa SMA diperoleh rerata skor komponen materi 92,5%, penyajian 88,5%, bahasa 84,17%, dan grafika 85,62%. Skor 87,5% menyatakan materi pada buku mudah dipahami dan 82,5% menyatakan penyajian materi dapat memotivasi untuk menggali informasi lebih lanjut. Dari hasil uji keterbacaan, buku ini memperoleh interpretasi keseluruhan sangat baik. Berdasarkan hasil uji kelayakan diperoleh rata-rata skor 81,05, menunjukkan buku pengayaan pengetahuan “Kajian Fisis Peristiwa Angin Puting Beliung” layak dengan predikat baik. Kata-kata kunci: buku pengayaan pengetahuan, angin puting beliung, tekanan, aliran gas

11 CFR 9003.2 - Candidate certifications.

Science.gov (United States)

2010-01-01

... funds under 11 CFR 9003.2(c)(3) shall not count against such candidate's $50,000 expenditure limitation... expenditures. (8) Expenditures made using a credit card for which the candidate is jointly or solely liable will count against the limits of this section to the extent that the full amount due, including any...

An objective framework to test the quality of candidate indicators of good environmental status

Directory of Open Access Journals (Sweden)

Ana M Queiros

2016-05-01

Full Text Available Large efforts are on-going within the EU to prepare the Marine Strategy Framework Directive’s (MSFD assessment of the environmental status of the European seas. This assessment will only be as good as the indicators chosen to monitor the eleven descriptors of good environmental status (GEnS. An objective and transparent framework to determine whether chosen indicators actually support the aims of this policy is, however, not yet in place. Such frameworks are needed to ensure that the limited resources available to this assessment optimize the likelihood of achieving GEnS within collaborating states. Here, we developed a hypothesis-based protocol to evaluate whether candidate indicators meet quality criteria explicit to the MSFD, which the assessment community aspires to. Eight quality criteria are distilled from existing initiatives, and a testing and scoring protocol for each of them is presented. We exemplify its application in three worked examples, covering indicators for three GEnS descriptors (1, 5 and 6, various habitat components (seaweeds, seagrasses, benthic macrofauna and plankton, and assessment regions (Danish, Lithuanian and UK waters. We argue that this framework provides a necessary, transparent and standardized structure to support the comparison of candidate indicators, and the decision-making process leading to indicator selection. Its application could help identify potential limitations in currently available candidate metrics and, in such cases, help focus the development of more adequate indicators. Use of such standardized approaches will facilitate the sharing of knowledge gained across the MSFD parties despite context-specificity across assessment regions, and support the evidence-based management of European seas.

HOT HIGH-MASS ACCRETION DISK CANDIDATES

International Nuclear Information System (INIS)

Beuther, H.; Walsh, A. J.; Longmore, S. N.

2009-01-01

To better understand the physical properties of accretion disks in high-mass star formation, we present a study of a dozen high-mass accretion disk candidates observed at high spatial resolution with the Australia Telescope Compact Array (ATCA) in the high-excitation (4,4) and (5,5) lines of NH 3 . All of our originally selected sources were detected in both NH 3 transitions, directly associated with CH 3 OH Class II maser emission and implying that high-excitation NH 3 lines are good tracers of the dense gas components in hot-core-type targets. Only the one source that did not satisfy the initial selection criteria remained undetected. From the 11 mapped sources, six show clear signatures of rotation and/or infall motions. These signatures vary from velocity gradients perpendicular to the outflows, to infall signatures in absorption against ultracompact H II regions, to more spherical infall signatures in emission. Although our spatial resolution is ∼1000 AU, we do not find clear Keplerian signatures in any of the sources. Furthermore, we also do not find flattened structures. In contrast to this, in several of the sources with rotational signatures, the spatial structure is approximately spherical with sizes exceeding 10 4 AU, showing considerable clumpy sub-structure at even smaller scales. This implies that on average typical Keplerian accretion disks-if they exist as expected-should be confined to regions usually smaller than 1000 AU. It is likely that these disks are fed by the larger-scale rotating envelope structure we observe here. Furthermore, we do detect 1.25 cm continuum emission in most fields of view. While in some cases weak cm continuum emission is associated with our targets, more typically larger-scale H II regions are seen offset more than 10'' from our sources. While these H II regions are unlikely to be directly related to the target regions, this spatial association nevertheless additionally stresses that high-mass star formation rarely

Psychometric Personality Differences Between Candidates in Astronaut Selection.

Science.gov (United States)

Mittelstädt, Justin M; Pecena, Yvonne; Oubaid, Viktor; Maschke, Peter

This paper investigates personality traits as potential factors for success in an astronaut selection by comparing personality profiles of unsuccessful and successful astronaut candidates in different phases of the ESA selection procedure. It is further addressed whether personality traits could predict an overall assessment rating at the end of the selection. In 2008/2009, ESA performed an astronaut selection with 902 candidates who were either psychologically recommended for mission training (N = 46) or failed in basic aptitude (N = 710) or Assessment Center and interview testing (N = 146). Candidates completed the Temperament Structure Scales (TSS) and the NEO Personality Inventory Revised (NEO-PI-R). Those candidates who failed in basic aptitude testing showed higher levels of Neuroticism (M = 49.8) than the candidates who passed that phase (M = 45.4 and M = 41.6). Additionally, candidates who failed in basic testing had lower levels of Agreeableness (M = 132.9) than recommended candidates (M = 138.1). TSS scales for Achievement (r = 0.19) and Vitality (r = 0.18) showed a significant correlation with the overall assessment rating given by a panel board after a final interview. Results indicate that a personality profile similar to Helmreich's "Right Stuff" is beneficial in astronaut selection. Influences of test anxiety on performance are discussed. Mittelstädt JM, Pecena Y, Oubaid V, Maschke P. Psychometric personality differences between candidates in astronaut selection. Aerosp Med Hum Perform. 2016; 87(11):933-939.

Decreased regional cerebral glucose metabolism in the prefrontal regions in adults' with internet game addiction

Energy Technology Data Exchange (ETDEWEB)

Park, Hyun Soo; Bang, Soong Ae; Yoon, Eun Jin; Cho, Sang Soo; Kim, Sang Hee; Kim, Yu Kyeong; Kim, Sang Eun [Seoul National Univ. College of Medicine, Seoul (Korea, Republic of)

2007-07-01

Internet Game Addiction (IGA) is known to be associated with poor decision-making and diminished impulse control; however, the underlying neural substrates of IGA have not been identified. To investigate the neural substrates of IGA, we compared regional cerebral glucose metabolism between adults with and without IGA, primarily in the prefrontal brain regions, which have been implicated in inhibitory control. We studied 10 right-handed participants (5 controls: male, 23.8{+-}0.75 y, 5 IGAs: male, 22.6{+-}2.42 y) with FDG PET. A standardized questionnaire was used to assess the severity of IGA. Before scanning, all subjects carried out a computerized version of the Iowa Gambling Task (IGT) and the Balloon Analogue Risk Task (BART), as measures of behavioral inhibitory control. Statistical Parametric Mapping 2 (SPM2) was used to analyze differences in regional brain glucose metabolism between adults with and without IGA. Consistent with our predictions, compared to controls, significant reductions in FDG uptake in individuals with IGA were found in the bilateral orbitofrontal gyrus (BA 11, 47), bilateral inferior frontal gyrus (BA 44, 48), cingulate cortex (BA 24), and bilateral supplementary motor area (SMA) (BA 6); whereas increases were found in the bilateral hippocampus. Correlation analyses within the IGA group further showed that the level of glucose metabolism in the right orbitofrontal gyrus was marginally positively correlated with task scores in BART. Our results showed that IGA is associated with reduced glucose metabolism in the prefrontal regions involved in inhibitory control. This finding highlights dysfunctional inhibitory brain systems in individuals with IGA and offers implications for the development for therapeutic paradigms for IGA.

Region-Based Building Rooftop Extraction and Change Detection

Science.gov (United States)

Tian, J.; Metzlaff, L.; d'Angelo, P.; Reinartz, P.

2017-09-01

Automatic extraction of building changes is important for many applications like disaster monitoring and city planning. Although a lot of research work is available based on 2D as well as 3D data, an improvement in accuracy and efficiency is still needed. The introducing of digital surface models (DSMs) to building change detection has strongly improved the resulting accuracy. In this paper, a post-classification approach is proposed for building change detection using satellite stereo imagery. Firstly, DSMs are generated from satellite stereo imagery and further refined by using a segmentation result obtained from the Sobel gradients of the panchromatic image. Besides the refined DSMs, the panchromatic image and the pansharpened multispectral image are used as input features for mean-shift segmentation. The DSM is used to calculate the nDSM, out of which the initial building candidate regions are extracted. The candidate mask is further refined by morphological filtering and by excluding shadow regions. Following this, all segments that overlap with a building candidate region are determined. A building oriented segments merging procedure is introduced to generate a final building rooftop mask. As the last step, object based change detection is performed by directly comparing the building rooftops extracted from the pre- and after-event imagery and by fusing the change indicators with the roof-top region map. A quantitative and qualitative assessment of the proposed approach is provided by using WorldView-2 satellite data from Istanbul, Turkey.

REGION-BASED BUILDING ROOFTOP EXTRACTION AND CHANGE DETECTION

Directory of Open Access Journals (Sweden)

J. Tian

2017-09-01

Full Text Available Automatic extraction of building changes is important for many applications like disaster monitoring and city planning. Although a lot of research work is available based on 2D as well as 3D data, an improvement in accuracy and efficiency is still needed. The introducing of digital surface models (DSMs to building change detection has strongly improved the resulting accuracy. In this paper, a post-classification approach is proposed for building change detection using satellite stereo imagery. Firstly, DSMs are generated from satellite stereo imagery and further refined by using a segmentation result obtained from the Sobel gradients of the panchromatic image. Besides the refined DSMs, the panchromatic image and the pansharpened multispectral image are used as input features for mean-shift segmentation. The DSM is used to calculate the nDSM, out of which the initial building candidate regions are extracted. The candidate mask is further refined by morphological filtering and by excluding shadow regions. Following this, all segments that overlap with a building candidate region are determined. A building oriented segments merging procedure is introduced to generate a final building rooftop mask. As the last step, object based change detection is performed by directly comparing the building rooftops extracted from the pre- and after-event imagery and by fusing the change indicators with the roof-top region map. A quantitative and qualitative assessment of the proposed approach is provided by using WorldView-2 satellite data from Istanbul, Turkey.

The Nature, Origin, and Importance of Carbonate-Bearing Samples at the Final Three Candidate Mars 2020 Landing Sites

Science.gov (United States)

Horgan, B.; Anderson, R. B.; Ruff, S. W.

2018-04-01

All three candidate Mars 2020 landing sites contain similar regional olivine/carbonate units, and a carbonate unit of possible lacustrine origin is also present at Jezero. Carbonates are critical for Mars Sample Return as records of climate and biosignatures.

Desarrollo de un modelo de simulación utilizando Sistemas Multi-Agente (SMA) aplicado al juego de la cerveza en el software Anylogic®

OpenAIRE

Uribe Vásquez, Juan Alejandro

2015-01-01

La simulación basada en sistemas multi-agentes (SMA) es un nuevo método de simulación que permite tratar de una manera sencilla la complejidad, la emergencia, y la no-linealidad típica de ciertos fenómenos en diversos ámbitos profesionales (medicina, bolsa, comercio electrónico, abastecimiento de la cadena de suministro, etc.) -- Aunque esta es una herramienta bastante habitual en las ciencias físicas y naturales aproximadamente hace tres décadas, ha sido utilizada recientemente en las cienci...

Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption.

Directory of Open Access Journals (Sweden)

Lauren A Vanderlinden

Full Text Available To identify brain transcriptional networks that may predispose an animal to consume alcohol, we used weighted gene coexpression network analysis (WGCNA. Candidate coexpression modules are those with an eigengene expression level that correlates significantly with the level of alcohol consumption across a panel of BXD recombinant inbred mouse strains, and that share a genomic region that regulates the module transcript expression levels (mQTL with a genomic region that regulates alcohol consumption (bQTL. To address a controversy regarding utility of gene expression profiles from whole brain, vs specific brain regions, as indicators of the relationship of gene expression to phenotype, we compared candidate coexpression modules from whole brain gene expression data (gathered with Affymetrix 430 v2 arrays in the Colorado laboratories and from gene expression data from 6 brain regions (nucleus accumbens (NA; prefrontal cortex (PFC; ventral tegmental area (VTA; striatum (ST; hippocampus (HP; cerebellum (CB available from GeneNetwork. The candidate modules were used to construct candidate eigengene networks across brain regions, resulting in three "meta-modules", composed of candidate modules from two or more brain regions (NA, PFC, ST, VTA and whole brain. To mitigate the potential influence of chromosomal location of transcripts and cis-eQTLs in linkage disequilibrium, we calculated a semi-partial correlation of the transcripts in the meta-modules with alcohol consumption conditional on the transcripts' cis-eQTLs. The function of transcripts that retained the correlation with the phenotype after correction for the strong genetic influence, implicates processes of protein metabolism in the ER and Golgi as influencing susceptibility to variation in alcohol consumption. Integration of these data with human GWAS provides further information on the function of polymorphisms associated with alcohol-related traits.

Investigating the psychological resilience, self-confidence and problem-solving skills of midwife candidates.

Science.gov (United States)

Ertekin Pinar, Sukran; Yildirim, Gulay; Sayin, Neslihan

2018-05-01

The high level of psychological resilience, self-confidence and problem solving skills of midwife candidates play an important role in increasing the quality of health care and in fulfilling their responsibilities towards patients. This study was conducted to investigate the psychological resilience, self-confidence and problem-solving skills of midwife candidates. It is a convenience descriptive quantitative study. Students who study at Health Sciences Faculty in Turkey's Central Anatolia Region. Midwife candidates (N = 270). In collection of data, the Personal Information Form, Psychological Resilience Scale for Adults (PRSA), Self-Confidence Scale (SCS), and Problem Solving Inventory (PSI) were used. There was a negatively moderate-level significant relationship between the Problem Solving Inventory scores and the Psychological Resilience Scale for Adults scores (r = -0.619; p = 0.000), and between Self-Confidence Scale scores (r = -0.524; p = 0.000). There was a positively moderate-level significant relationship between the Psychological Resilience Scale for Adults scores and the Self-Confidence Scale scores (r = 0.583; p = 0.000). There was a statistically significant difference (p Problem Solving Inventory and the Psychological Resilience Scale for Adults scores according to getting support in a difficult situation. As psychological resilience and self-confidence levels increase, problem-solving skills increase; additionally, as self-confidence increases, psychological resilience increases too. Psychological resilience, self-confidence, and problem-solving skills of midwife candidates in their first-year of studies are higher than those who are in their fourth year. Self-confidence and psychological resilience of midwife candidates aged between 17 and 21, self-confidence and problem solving skills of residents of city centers, psychological resilience of those who perceive their monthly income as sufficient are high

An Extremely Red and Two Other Nearby L Dwarf Candidates Previously Overlooked in 2MASS, WISE, and Other Surveys

Science.gov (United States)

Scholz, Ralf-Dieter; Bell, Cameron P. M.

2018-02-01

We present three new nearby L dwarf candidates, found in a continued combined color/proper motion search using WISE, 2MASS, and other survey data, where we included extended WISE sources and looked closer to the Galactic plane region. Their spectral types and distances were estimated from photometric comparisons to well-known L dwarfs with trigonometric parallaxes. The first object, 2MASS J07555430-3259589, is an extremely red L7.5p dwarf candidate at a photometric distance of about 16 pc. Its position, proper motion and distance are consistent with membership in the Carina-Near young moving group. The second one, 2MASS J07414279-0506464, is resolved in Gaia DR1 as a close binary (separation 0.3 arcsec), and we classify it as a equal-mass binary candidate consisting of two L5 dwarfs at 19 pc. Our nearest new neighbor, 2MASS J19251275+0700362, is an L7 dwarf candidate at 10 pc.

Design and numerical analysis of an SMA mesh-based self-folding sheet

International Nuclear Information System (INIS)

Peraza-Hernandez, Edwin A; Hartl, Darren J; Malak Jr, Richard J

2013-01-01

Origami engineering, which is the practice of creating useful three-dimensional structures through folding and fold-like operations applied to initially two-dimensional entities, has the potential to impact several areas of design and manufacturing. In some instances, however, it may be impractical to apply external manipulations to produce the desired folds (e.g., as in remote applications such as space systems). In such cases, self-folding capabilities are valuable. A self-folding material or material system is one that can perform folding operations without manipulations from external forces. This work considers a concept for a self-folding material system. The system extends the ‘programmable matter’ concept and consists of an active, self-morphing sheet composed of two meshes of thermally actuated shape memory alloy (SMA) wire separated by a compliant passive layer. The geometric and power input parameters of the self-folding sheet are optimized to achieve the tightest local fold possible subject to stress and temperature constraints. The sheet folding performance considering folds at different angles relative to the orientation of the wire mesh is also analyzed. The optimization results show that a relatively low elastomer thickness is preferable to generate the tightest fold possible. The results also show that the self-folding sheet does not require large power inputs to achieve an optimal folding performance. It was shown that the self-folding sheet is capable of creating similar quality folds at different orientations. (paper)

Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes

DEFF Research Database (Denmark)

Storling, Joachim; Brorsson, Caroline Anna

2013-01-01

In type 1 diabetes (T1D), the insulin-producing β cells are destroyed by an immune-mediated process leading to complete insulin deficiency. There is a strong genetic component in T1D. Genes located in the human leukocyte antigen (HLA) region are the most important genetic determinants of disease......, but more than 40 additional loci are known to significantly affect T1D risk. Since most of the currently known genetic candidates have annotated immune cell functions, it is generally considered that most of the genetic susceptibility in T1D is caused by variation in genes affecting immune cell function....... Recent studies, however, indicate that most T1D candidate genes are expressed in human islets suggesting that the functions of the genes are not restricted to immune cells, but also play roles in the islets and possibly the β cells. Several candidates change expression levels within the islets following...

Survey of Swedish buffer material candidates and methods for characterization

International Nuclear Information System (INIS)

Erlstroem, M.; Pusch, R.

1987-12-01

The study has given a good overview of potential clay buffer candidates in the part of Sweden that offers the best possibilities to find large accessible quantities of smectitic materials. The most promising Scanian materials are those in the Kaageroed and Vallaakra (Margreteberg) areas since they represent the most smectitic ones, which may serve as raw material for the production of canister embedment. The moraine clays in the Lund-Landskrona region seem to be useful for backfilling purposes. A refined version of Reynolds technique is suggested as an SKB standard for prospecting and characterization of buffer materials. (orig./DG)

Dark Matter candidates in a baryogenesis inspired scenario

International Nuclear Information System (INIS)

Provenza, A; Quiros, M; Ullio, P

2006-01-01

It has recently been shown that the electroweak baryogenesis mechanism is feasible in Standard Model extensions containing extra fermions with large Yukawa couplings. We show that the lightest of these fermionic fields can naturally be a good candidate for cold dark matter. We find regions in the parameter space where the thermal relic abundance of this particle is compatible with the dark matter density of the Universe as determined by the WMAP experiment. We study direct and indirect dark matter detection for this model and compare with current experimental limits and prospects for upcoming experiments. We find, contrary to the standard lore, that indirect detection searches are more promising than direct ones, and they already exclude part of the parameter space

PENGARUH PEMAHAMAN KURIKULUM, SUPERVISI AKADEMIK, DAN FASILITAS KERJA TERHADAP KINERJA GURU EKONOMI SMA/MA NEGERI DI KOTA MAGELANG

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Oky Estiana Putri

2016-02-01

Full Text Available Pada era globalisasi dewasa ini pendidikan menjadi sangatpenting. Bekal pendidikan yang dimiliki suatu masyarakat akan berkembang secara baik, dan tidak dapat dipungkiri masyarakat tersebut semakin berkualitas sertamampu bersaing secara kompetitif di era persaingan yang semakin ketat. Dalam suasana kompetitif semacam ini diperlukan sumber daya yang berkualitas. Untuk menciptakan sumber daya berkualitas diperlukan pendidik yang profesional. Keprofesionalan seorang pendidik dapat dilihat melalui kinerjanya yang baik. Kondisi di lapangan, kinerja guru di Kota Magelang masih belum optimal. Populasi penelitian ini adalah guru mata pelajaran Ekonomi/Akuntasi SMA/MA Negeri di Kota Magelang yang berjumlah 30 orang. Metode pengumpulan data menggunakan kuesioner. Data variabel dianalisis dengan statistik deskriptif dan analisis regresi berganda. Hasil penelitian menunjukkan bahwa pemahaman kurikulum, supervisi akademik, dan fasilitas kerja berpengaruh secara simultan terhadap kinerja guru sebesar 82,8%. Pengaruh secara parsial juga didapatkan pada variable independen terhadap variabel dependen. Pemahaman kurikulum berpengaruh positif dan signifikan terhadap kinerja guru ekonomi SMA/MA Negeri sebesar 24,70%. Supervisi akademik berpengaruh positif dan signifikan terhadap kinerja guru ekonomi SMA/MA Negeri sebesar 19,54%, serta fasilitas kerja berpengaruh positif dan signifikan terhadap kinerja guru sebesar 23,42%. Saran yang dapat diberikan adalah para guru hendaknya lebih meningkatkan pemahaman kurikulum supaya kinerjanya semakin baik. Bagi kepala sekolah hendaknya lebih memperhatikan lagi guru-guru dengan kegiatan supervisi akademik, dengan merasa diperhatikan, mendapat dorongan dan bantuan dari kepala sekolah guru akan lebih berusaha meningkatkan kinerjanya menjadi semakin baik. Sekolah hendaknya menyediakan fasilitas kerja yang lebih baik lagi, nyaman dan lengkap supaya guru merasa puas dan kinerjanya akan semakin baik. In the era of globalization

Linkage mapping of candidate genes for induce resistance and growth promotion by trichoderma koningiopsis (th003) in tomato solanum lycopersicum

International Nuclear Information System (INIS)

Simbaqueba, Jaime; Cotes, Alba Marina; Barrero, Luz Stella

2011-01-01

Induced systemic resistance (ISR) is a mechanism by which plants enhance defenses against any stress condition. ISR and growth promotion are enhanced when tomato (Solanum lycopersicum) is inoculated with several strains of Trichoderma ssp. this study aims to genetically map tomato candidate genes involved in ISR and growth promotion induced by the Colombian native isolate Trichoderma koningiopsis th003. Forty-nine candidate genes previously identified on tomato plants treated with th003 and T. hamatum T382 strains were evaluated for polymorphisms and 16 of them were integrated on the highly saturated genetic linkage map named TOMATO EXPEN 2000. The location of six unigenes was similar to the location of resistance gene analogs (RGAS), defense related ests and resistance QTLs previously reported, suggesting new possible candidates for these quantitative trait loci (QTL) regions. The candidate gene-markers may be used for future ISR or growth promotion assisted selection in tomato.

Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19

Directory of Open Access Journals (Sweden)

Ferrell Robert E

2011-01-01

Full Text Available Abstract Background Abdominal aortic aneurysm (AAA is a complex disorder with multiple genetic risk factors. Using affected relative pair linkage analysis, we previously identified an AAA susceptibility locus on chromosome 19q13. This locus has been designated as the AAA1 susceptibility locus in the Online Mendelian Inheritance in Man (OMIM database. Methods Nine candidate genes were selected from the AAA1 locus based on their function, as well as mRNA expression levels in the aorta. A sample of 394 cases and 419 controls was genotyped for 41 SNPs located in or around the selected nine candidate genes using the Illumina GoldenGate platform. Single marker and haplotype analyses were performed. Three genes (CEBPG, PEPD and CD22 were selected for DNA sequencing based on the association study results, and exonic regions were analyzed. Immunohistochemical staining of aortic tissue sections from AAA and control individuals was carried out for the CD22 and PEPD proteins with specific antibodies. Results Several SNPs were nominally associated with AAA (p CEBPG, peptidase D (PEPD, and CD22. Haplotype analysis found a nominally associated 5-SNP haplotype in the CEBPG/PEPD locus, as well as a nominally associated 2-SNP haplotype in the CD22 locus. DNA sequencing of the coding regions revealed no variation in CEBPG. Seven sequence variants were identified in PEPD, including three not present in the NCBI SNP (dbSNP database. Sequencing of all 14 exons of CD22 identified 20 sequence variants, five of which were in the coding region and six were in the 3'-untranslated region. Five variants were not present in dbSNP. Immunohistochemical staining for CD22 revealed protein expression in lymphocytes present in the aneurysmal aortic wall only and no detectable expression in control aorta. PEPD protein was expressed in fibroblasts and myofibroblasts in the media-adventitia border in both aneurysmal and non-aneurysmal tissue samples. Conclusions Association testing

Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1.

Directory of Open Access Journals (Sweden)

Caroline Kulangara

Full Text Available In a genome-wide screen for alpha-helical coiled coil motifs aiming at structurally defined vaccine candidates we identified PFF0165c. This protein is exported in the trophozoite stage and was named accordingly Trophozoite exported protein 1 (Tex1. In an extensive preclinical evaluation of its coiled coil peptides Tex1 was identified as promising novel malaria vaccine candidate providing the rational for a comprehensive cell biological characterization of Tex1. Antibodies generated against an intrinsically unstructured N-terminal region of Tex1 and against a coiled coil domain were used to investigate cytological localization, solubility and expression profile. Co-localization experiments revealed that Tex1 is exported across the parasitophorous vacuole membrane and located to Maurer's clefts. Change in location is accompanied by a change in solubility: from a soluble state within the parasite to a membrane-associated state after export to Maurer's clefts. No classical export motifs such as PEXEL, signal sequence/anchor or transmembrane domain was identified for Tex1.

TEACHERS' PERCEPTIONS ON THE MODEL DEVELOPMENT OF CHARACTER BASED TEACHING MATERIAL FOR SMA/ MA STUDENTS IN SEMARANG

Directory of Open Access Journals (Sweden)

Suwandi Suwandi

2016-01-01

Full Text Available This study was conducted with the objectives of finding out whether or not the teaching material entitled "English for Better Character" developed by the researchers through R&D was appropriate seen from the point of view of the teachers' perception. Seven English teachers from 7 Senior High Schools and Madrasah Aliyah in Semarang were taken as samples. Data were collected using questionnaires and analyzed by using Likert scale with the criteria of 5:excellent, 4:good, 3:fair, 2:poor, and bvery poor. The questionnaires contained three main aspects, such as the content appropriacy, the presentation appropriacy, and the technique appropriacy. As a whole, the mean of all aspects was 4,12. It indicates that it belongs to the criteria of very good with the following percentage, content: 32,44%, presentation: 32,18% and language: 35,52%. In conclusion, the teaching material for SMA/MA students developed by the researchers is suitable to be used as a teaching material.

PEACE: pulsar evaluation algorithm for candidate extraction - a software package for post-analysis processing of pulsar survey candidates

NARCIS (Netherlands)

Lee, K.J.; Stovall, K.; Jenet, F.A.; Martinez, J.; Dartez, L.P.; Mata, A.; Lunsford, G.; Cohen, S.; Biwer, C.M.; Rohr, M.; Flanigan, J.; Walker, A.; Banaszak, S.; Allen, B.; Barr, E.D.; Bhat, N.D.R.; Bogdanov, S.; Brazier, A.; Camilo, F.; Champion, D.J.; Chatterjee, S.; Cordes, J.; Crawford, F.; Deneva, J.; Desvignes, G.; Ferdman, R.D.; Freire, P.; Hessels, J.W.T.; Karuppusamy, R.; Kaspi, V.M.; Knispel, B.; Kramer, M.; Lazarus, P.; Lynch, R.; Lyne, A.; McLaughlin, M.; Ransom, S.; Scholz, P.; Siemens, X.; Spitler, L.; Stairs, I.; Tan, M.; van Leeuwen, J.; Zhu, W.W.

2013-01-01

Modern radio pulsar surveys produce a large volume of prospective candidates, the majority of which are polluted by human-created radio frequency interference or other forms of noise. Typically, large numbers of candidates need to be visually inspected in order to determine if they are real pulsars.

Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study.

LENUS (Irish Health Repository)

Brophy, Karen

2010-01-01

BACKGROUND: Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with a clear functional role in T-cell regulation. Furthermore, the newly discovered risk loci, together with the well established HLA locus, account for less than 50% of the heritability of CD, suggesting that numerous additional loci remain undiscovered. Linkage studies have identified some well-replicated risk regions, most notably chromosome 5q31 and 11q23. METHODS: We have evaluated six candidate genes in one of these regions (11q23), namely CD3E, CD3D, CD3G, IL10RA, THY1 and IL18, as risk factors for CD using a 2-phase candidate gene approach directed at chromosome 11q. 377 CD cases and 349 ethnically matched controls were used in the initial screening, followed by an extended sample of 171 additional coeliac cases and 536 additional controls. RESULTS: Promotor SNPs (-607, -137) in the IL18 gene, which has shown association with several autoimmune diseases, initially suggested association with CD (P < 0.05). Follow-up analyses of an extended sample supported the same, moderate effect (P < 0.05) for one of these. Haplotype analysis of IL18-137\\/-607 also supported this effect, primarily due to one relatively rare haplotype IL18-607C\\/-137C (P < 0.0001), which was independently associated in two case-control comparisons. This same haplotype has been noted in rheumatoid arthritis. CONCLUSION: Haplotypes of the IL18 promotor region may contribute to CD risk, consistent with this cytokine\\'s role in maintaining inflammation in active CD.

Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study

LENUS (Irish Health Repository)

Brophy, Karen

2010-05-17

Abstract Background Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with a clear functional role in T-cell regulation. Furthermore, the newly discovered risk loci, together with the well established HLA locus, account for less than 50% of the heritability of CD, suggesting that numerous additional loci remain undiscovered. Linkage studies have identified some well-replicated risk regions, most notably chromosome 5q31 and 11q23. Methods We have evaluated six candidate genes in one of these regions (11q23), namely CD3E, CD3D, CD3G, IL10RA, THY1 and IL18, as risk factors for CD using a 2-phase candidate gene approach directed at chromosome 11q. 377 CD cases and 349 ethnically matched controls were used in the initial screening, followed by an extended sample of 171 additional coeliac cases and 536 additional controls. Results Promotor SNPs (-607, -137) in the IL18 gene, which has shown association with several autoimmune diseases, initially suggested association with CD (P < 0.05). Follow-up analyses of an extended sample supported the same, moderate effect (P < 0.05) for one of these. Haplotype analysis of IL18-137\\/-607 also supported this effect, primarily due to one relatively rare haplotype IL18-607C\\/-137C (P < 0.0001), which was independently associated in two case-control comparisons. This same haplotype has been noted in rheumatoid arthritis. Conclusion Haplotypes of the IL18 promotor region may contribute to CD risk, consistent with this cytokine\\'s role in maintaining inflammation in active CD.

Elections, Information, and State-Dependent Candidate Quality

DEFF Research Database (Denmark)

Jensen, Thomas

voters are uncertain about the state. Candidates are fully informed and completely office-motivated. With a reasonable restriction on voters' beliefs, an equilibrium where candidates' positions reveal the true state does not exist. Non-revealing equilibria always exist. Some main findings...

Study of a few cluster candidates in the Magellanic Bridge

Science.gov (United States)

Choudhury, Samyaday; Subramaniam Subramaniam, Annapurni; Sohn, Young-Jong

2018-06-01

The Magellanic Clouds (LMC & SMC) are gas rich, metal poor, dwarf satellite galaxies to our Milky Way that are interacting with each other. The Magellanic Bridge (MB), joining the larger and smaller Cloud is considered to be a signature of this interaction process. Studies have revealed that the MB, apart from gas also hosts stellar populations and star clusters. The number of clusters, with well-estimated parameters within the MB is still underway. In this work, we study a sample of 9 previously cataloged star clusters in the MB region. We use Washington C, Harris R and Cousins I bands data from literature, taken using the 4-m Blanco telescope to estimate the cluster properties (size, age, reddening). We also identify and separate out genuine cluster candidates from possible clusters/asterism. The increase in number of genuine cluster candidates with well-estimated parameters is important in the context of understanding cluster formation and evolution in such low-metallicity, and tidally disrupted environment. The clusters studied here can also help estimate distances to different parts of the MB, as recent studies indicate that portions of MB near the SMC is a closer to us, than the LMC.

French presidential election: nuclear energy in candidates' program

International Nuclear Information System (INIS)

Le Ngoc, B.

2017-01-01

Generally right candidates consider nuclear energy as a chance for France because it is an industrial asset for the country, it releases no greenhouse gases and has given France its large energy independence. They are ready to reconsider the limitation imposed on the share of nuclear energy in the future energy mix and they want to reinforce research for next generations of reactors. The far-right candidate wishes to use nuclear energy massively to produce hydrogen in order to reduce by half the consumption of fossil energies in 20 years. Generally left candidates back the law on the energy transition that was passed during last legislature and that limits the nuclear power share to 50% while developing green energies. The far-left candidates wish a progressive and complete abandon of nuclear energy. All candidates wish a greater share of renewable energies in the future energy mix. (A.C.)

Waiting narratives of lung transplant candidates.

Science.gov (United States)

Yelle, Maria T; Stevens, Patricia E; Lanuza, Dorothy M

2013-01-01

Before 2005, time accrued on the lung transplant waiting list counted towards who was next in line for a donor lung. Then in 2005 the lung allocation scoring system was implemented, which meant the higher the illness severity scores, the higher the priority on the transplant list. Little is known of the lung transplant candidates who were listed before 2005 and were caught in the transition when the lung allocation scoring system was implemented. A narrative analysis was conducted to explore the illness narratives of seven lung transplant candidates between 2006 and 2007. Arthur Kleinman's concept of illness narratives was used as a conceptual framework for this study to give voice to the illness narratives of lung transplant candidates. Results of this study illustrate that lung transplant candidates expressed a need to tell their personal story of waiting and to be heard. Recommendation from this study calls for healthcare providers to create the time to enable illness narratives of the suffering of waiting to be told. Narrative skills of listening to stories of emotional suffering would enhance how healthcare providers could attend to patients' stories and hear what is most meaningful in their lives.

Waiting Narratives of Lung Transplant Candidates

Directory of Open Access Journals (Sweden)

Maria T. Yelle

2013-01-01

Full Text Available Before 2005, time accrued on the lung transplant waiting list counted towards who was next in line for a donor lung. Then in 2005 the lung allocation scoring system was implemented, which meant the higher the illness severity scores, the higher the priority on the transplant list. Little is known of the lung transplant candidates who were listed before 2005 and were caught in the transition when the lung allocation scoring system was implemented. A narrative analysis was conducted to explore the illness narratives of seven lung transplant candidates between 2006 and 2007. Arthur Kleinman’s concept of illness narratives was used as a conceptual framework for this study to give voice to the illness narratives of lung transplant candidates. Results of this study illustrate that lung transplant candidates expressed a need to tell their personal story of waiting and to be heard. Recommendation from this study calls for healthcare providers to create the time to enable illness narratives of the suffering of waiting to be told. Narrative skills of listening to stories of emotional suffering would enhance how healthcare providers could attend to patients’ stories and hear what is most meaningful in their lives.

Penerapan Pendekatan Contextual Teaching and Learning (Ctl) Dengan Model Problem Posing Untuk Meningkatkan Kualitas Pembelajaran Biologi Siswa Kelas X.2 SMA Negeri 2 Karanganyar Tahun Pelajaran 2011/2012

OpenAIRE

Suparmi, Suparmi; Suciati, Suciati; Harlita, Harlita

2013-01-01

– This research aims to improve low quality of biology in class X.2 SMA Negeri 2 Karanganyar in academic year 2011/2012. Learning considered by teacher's performance, utility of facilities in the classroom, classroom climate, student's scientific attitude, and student motivation of achievement applying for approach Contextual Teaching and Learning with Problem Posing model. This research was a classroom action research which and performed in three cycles. Each cycle consisted of 4 ...

Candidate gene association mapping of Sclerotinia stalk rot resistance in sunflower (Helianthus annuus L.) uncovers the importance of COI1 homologs.

Science.gov (United States)

Talukder, Zahirul I; Hulke, Brent S; Qi, Lili; Scheffler, Brian E; Pegadaraju, Venkatramana; McPhee, Kevin; Gulya, Thomas J

2014-01-01

Functional markers for Sclerotinia basal stalk rot resistance in sunflower were obtained using gene-level information from the model species Arabidopsis thaliana. Sclerotinia stalk rot, caused by Sclerotinia sclerotiorum, is one of the most destructive diseases of sunflower (Helianthus annuus L.) worldwide. Markers for genes controlling resistance to S. sclerotiorum will enable efficient marker-assisted selection (MAS). We sequenced eight candidate genes homologous to Arabidopsis thaliana defense genes known to be associated with Sclerotinia disease resistance in a sunflower association mapping population evaluated for Sclerotinia stalk rot resistance. The total candidate gene sequence regions covered a concatenated length of 3,791 bp per individual. A total of 187 polymorphic sites were detected for all candidate gene sequences, 149 of which were single nucleotide polymorphisms (SNPs) and 38 were insertions/deletions. Eight SNPs in the coding regions led to changes in amino acid codons. Linkage disequilibrium decay throughout the candidate gene regions declined on average to an r (2) = 0.2 for genetic intervals of 120 bp, but extended up to 350 bp with r (2) = 0.1. A general linear model with modification to account for population structure was found the best fitting model for this population and was used for association mapping. Both HaCOI1-1 and HaCOI1-2 were found to be strongly associated with Sclerotinia stalk rot resistance and explained 7.4 % of phenotypic variation in this population. These SNP markers associated with Sclerotinia stalk rot resistance can potentially be applied to the selection of favorable genotypes, which will significantly improve the efficiency of MAS during the development of stalk rot resistant cultivars.

Indico CONFERENCE: Candidate participant's registration/application

CERN Multimedia

CERN. Geneva; Ferreira, Pedro

2017-01-01

In this tutorial you are going to learn how to apply as a candidate participant (if the event requires approval from the event manager) or to register (if participation to the event doesn't require approval from an event manager) to the conference using the registration form for the event. You are also going to learn how to approve a candidate participant's application as an event manager.

Identification of Novel Potential Vaccine Candidates against Tuberculosis Based on Reverse Vaccinology

Directory of Open Access Journals (Sweden)

Gloria P. Monterrubio-López

2015-01-01

Full Text Available Tuberculosis (TB is a chronic infectious disease, considered as the second leading cause of death worldwide, caused by Mycobacterium tuberculosis. The limited efficacy of the bacillus Calmette-Guérin (BCG vaccine against pulmonary TB and the emergence of multidrug-resistant TB warrants the need for more efficacious vaccines. Reverse vaccinology uses the entire proteome of a pathogen to select the best vaccine antigens by in silico approaches. M. tuberculosis H37Rv proteome was analyzed with NERVE (New Enhanced Reverse Vaccinology Environment prediction software to identify potential vaccine targets; these 331 proteins were further analyzed with VaxiJen for the determination of their antigenicity value. Only candidates with values ≥0.5 of antigenicity and 50% of adhesin probability and without homology with human proteins or transmembrane regions were selected, resulting in 73 antigens. These proteins were grouped by families in seven groups and analyzed by amino acid sequence alignments, selecting 16 representative proteins. For each candidate, a search of the literature and protein analysis with different bioinformatics tools, as well as a simulation of the immune response, was conducted. Finally, we selected six novel vaccine candidates, EsxL, PE26, PPE65, PE_PGRS49, PBP1, and Erp, from M. tuberculosis that can be used to improve or design new TB vaccines.

Rancang Bangun Aplikasi Pembayaran Sekolah Menggunakan Java Dan MySQL Berbasis Client Server Di SMA Yos Sudarso Cilacap

Directory of Open Access Journals (Sweden)

Elisa Usada

2010-11-01

Full Text Available SMA Yos Sudarso merupakan salah satu sekolah yang sudah memanfaatkan komputer  untuk menyelesaikan berbagai macam tugas, tetapi pemanfaatannya masih belum maksimal karena ada bagian administrasi yang masih menggunakan metode manual, yaitu pada administrasi pembayaran. Penelitian ini  berusaha membuat sebuah aplikasi client server berteknologi JAVA dan MySQL untuk mengelola data pembayaran sekolah meliputi pembayaran SPP, pembayaran uang gedung serta pembayaran ujian. Metode waterfall digunakan sebagai acuan perancangan dan pengembangan aplikasi. Alat abstraksi sistem yang digunakan adalah use case diagram dan class diagram. Perancangan basis data dengan menggunakan ERD. Pengujian dilakukan dengan metode black box yaitu hanya menguji jalannya fungsi-fungsi yang telah direncanakan tanpa mempedulikan aspek proses internal dalam kode dan algoritma. Pengujian memberikan hasil bahwa aplikasi dapat dijalankan secara client server dan fungsi dapat berjalan semestinya. Proses back up data otomatis menjadi kekurangan dari aplikasi dalam penelitian ini.

PENGARUH MODEL PEMBELAJARAN INKUIRI TERBIMBING BERBANTUAN MULTIMEDIA INTERAKTIF TERHADAP BERPIKIR KRITIS SISWA KELAS XI SMA NEGERI DI BOJONEGORO

Directory of Open Access Journals (Sweden)

Nilam Retnosari

2016-08-01

Berpikir kritis (critical thinking merupakan salah satu kecakapan berpikir yang penting pada abad XXI. Hasil TIMSS menunjukkan rata-rata kemampuan domain penalaran dan penerapan relatif rendah. Salah satu model pembelajaran yang diamanatkan Kurikulum 2013 adalah inkuiri terbimbing yang pelaksanaannya membutuhkan peran sumber belajar, seperti multimedia interaktif. Penelitian ini bertujuan untuk mengetahui pengaruh inkuiri terbimbing berbantuan multimedia interaktif terhadap keterampilan berpikir kritis. Penelitian ini merupakan Quasi Experiment. Populasi penelitian adalah seluruh siswa di SMA Negeri 1 Sumberrejo Tahun Ajaran 2015/2016 dengan sampel siswa kelas XI IPA 1, IPA 2, dan IPA 5. Penelitian dilakukan pada bulan April—Mei 2016. Instrumen berupa soal tes keterampilan berpikir kritis. Data dianalisis dengan kovarian (Anakova. Hasil penelitian menunjukkan bahwa inkuiri terbimbing berbantuan multimedia interaktif berpengaruh terhadap keterampilan berpikir kritis siswa. Hasil uji LSD menunjukkan keterampilan berpikir kritis siswa meningkat sebesar 400,2% pada kelas inkuiri terbimbing dan 416,8% pada kelas inkuiri terbimbing berbantuan multimedia.

Rancang Bangun Sistem Informasi Akademik Berbasis Web ( studi kasus: SMA Swasta Harapan I Medan

Directory of Open Access Journals (Sweden)

Haida Dafitri, Marina Elsera

2017-10-01

Full Text Available Submission of academic information to students, parents / guardians conducted at private high school SMA Harapan I Medan are still very ineffective and efficient both in terms of delivery time and in terms of finance. This is because the academic delivery is still manual in oral, written or via phone or SMS one by one. The impact of the process is the slow process of delivering academic information and the amount of expenditure in the delivery of information. To overcome these problems, then the academic community wants to improve the delivery of academic information systems using computerized technology. The purpose of the change is by building a School of Academic Information System (SISFO Web-based SCRUM model. The system is built to produce academic information such as value and achievement of students in web-based schools that can be utilized by the academic staff to make it easier in conveying academic information to students, parents / guardians. This system includes and through several aspects of functionality, reliability, efficiency, and usability. And the scrum model used in the design of this system has a framework for building, developing and managing an ever-changing product. Keywords: Information , Academic, Scrum Model, Web

Preliminary assessment of nuclear waste transportation cost and risk for operation of the first repository at candidate sites

International Nuclear Information System (INIS)

Peterson, R.W.; McSweeney, T.I.; Varadarajan, R.V.; Wilmot, E.L.; Cashwell, J.W.; Joy, D.S.

1983-01-01

To support the selection of the first commercial nuclear waste repository site in 1987, environmental analyses of five candidate site locations are currently being performed. The five locations are in the Gulf Interior Region, the Permian Basin, the Paradox Basin, Yucca Mountain and the Hanford reservation. Costs and operational risks associated with the transportation of nuclear wastes to a single repository located in these regions have been calculated for a life-cycle of 26 years

Looking into flowering time in almond (Prunus dulcis (Mill) D. A. Webb): the candidate gene approach.

Science.gov (United States)

Silva, C; Garcia-Mas, J; Sánchez, A M; Arús, P; Oliveira, M M

2005-03-01

Blooming time is one of the most important agronomic traits in almond. Biochemical and molecular events underlying flowering regulation must be understood before methods to stimulate late flowering can be developed. Attempts to elucidate the genetic control of this process have led to the identification of a major gene (Lb) and quantitative trait loci (QTLs) linked to observed phenotypic differences, but although this gene and these QTLs have been placed on the Prunus reference genetic map, their sequences and specific functions remain unknown. The aim of our investigation was to associate these loci with known genes using a candidate gene approach. Two almond cDNAs and eight Prunus expressed sequence tags were selected as candidate genes (CGs) since their sequences were highly identical to those of flowering regulatory genes characterized in other species. The CGs were amplified from both parental lines of the mapping population using specific primers. Sequence comparison revealed DNA polymorphisms between the parental lines, mainly of the single nucleotide type. Polymorphisms were used to develop co-dominant cleaved amplified polymorphic sequence markers or length polymorphisms based on insertion/deletion events for mapping the candidate genes on the Prunus reference map. Ten candidate genes were assigned to six linkage groups in the Prunus genome. The positions of two of these were compatible with the regions where two QTLs for blooming time were detected. One additional candidate was localized close to the position of the Evergrowing gene, which determines a non-deciduous behaviour in peach.

PENGARUH PENGGUNAAN PEMBELAJARAN KOOPERATIF TIPE STAD BERBANTUAN WINGEOM TERHADAP KEMAMPUAN PEMECAHAN MASALAH GEOMETRI SISWA SMA

Directory of Open Access Journals (Sweden)

Ikhsanudin Ikhsanudin

2014-06-01

Full Text Available This research is a quasi-experimental with pre-test and post-test non-equivalent group design. The population in this research is all of the students on class X in SMA Negeri 1 Marga Tiga and the sampling technique is total sampling. Data are collected by documentation and test. Data are analyzed with descriptive statistics to compare the mean scores of N-Gain  obtained by each student.  The results of the analysis shows that (1 the student’s geometry problem solving ability with cooperative learning STAD is higher than the conventional learning, (2 the student’s geometry problem solving ability with wingeom software in cooperative learning STAD is higher than the conventional learning, (3 the student’s geometry problem solving ability with wingeom software in cooperative learning STAD is higher than without using wingeom software. This research shows that the cooperative learning STAD by using the wingeom software has a significant effect on the high school students’ geometry problem-solving ability. The finding of this research shows that the students are still having difficulties in solving the problems, especially when the students have to look back whether the finishing is right or not.

Using the adaptive SMA composite cylinder concept to reduce radial dilation in composite pressure vessels

Science.gov (United States)

Paine, Jeffrey S.; Rogers, Craig A.

1995-05-01

Composite materials are widely used in the design of pressurized gas and fluid vessels for applications ranging from underground gasoline storage tanks to rocket motors for the space shuttle. In the design of a high pressure composite vessel (Pi > 12 Ksi), thick-wall (R/h short term dilation and long term creep are not problematic for applications requiring only the containment of the pressurized fluid. In applications where metallic liners are required, however, substantial dilation and creep causes plastic yielding which leads to reduced fatigue life. To applications such as a hydraulic accumulator, where a piston is employed to fit and seal the fluid in the composite cylinder, the dilation and creep may allow leakage and pressure loss around the piston. A concept called the adaptive composite cylinder is experimentally presented. Shape memory alloy wire in epoxy resin is wrapped around or within polymer matrix composite cylinders to reduce radial dilation of the cylinder. Experimental results are presented that demonstrate the ability of the SMA wire layers to reduce radial dilation. Results from experimental testing of the recovery stress fatigue response of nitinol shape memory alloy wires is also presented.

Developing Potential Candidates of Preclinical Preeclampsia

Directory of Open Access Journals (Sweden)

Sandra Founds

2015-11-01

Full Text Available The potential for developing molecules of interest in preclinical preeclampsia from candidate genes that were discovered on gene expression microarray analysis has been challenged by limited access to additional first trimester trophoblast and decidual tissues. The question of whether these candidates encode secreted proteins that may be detected in maternal circulation early in pregnancy has been investigated using various proteomic methods. Pilot studies utilizing mass spectrometry based proteomic assays, along with enzyme linked immunosorbent assays (ELISAs, and Western immunoblotting in first trimester samples are reported. The novel targeted mass spectrometry methods led to robust multiple reaction monitoring assays. Despite detection of several candidates in early gestation, challenges persist. Future antibody-based studies may lead to a novel multiplex protein panel for screening or detection to prevent or mitigate preeclampsia.

An annotated history of container candidate material selection

International Nuclear Information System (INIS)

McCright, R.D.

1988-07-01

This paper documents events in the Nevada Nuclear Waste Storage Investigations (NNWSI) Project that have influenced the selection of metals and alloys proposed for fabrication of waste package containers for permanent disposal of high-level nuclear waste in a repository at Yucca Mountain, Nevada. The time period from 1981 to 1988 is covered in this annotated history. The history traces the candidate materials that have been considered at different stages of site characterization planning activities. At present, six candidate materials are considered and described in the 1988 Consultation Draft of the NNWSI Site Characterization Plan (SCP). The six materials are grouped into two alloy families, copper-base materials and iron to nickel-base materials with an austenitic structure. The three austenitic candidates resulted from a 1983 survey of a longer list of candidate materials; the other three candidates resulted from a special request from DOE in 1984 to evaluate copper and copper-base alloys. 24 refs., 2 tabs

USING STELLAR DENSITIES TO EVALUATE TRANSITING EXOPLANETARY CANDIDATES

International Nuclear Information System (INIS)

Tingley, B.; Deeg, H. J.; Bonomo, A. S.

2011-01-01

One of the persistent complications in searches for transiting exoplanets is the low percentage of the detected candidates that ultimately prove to be planets, which significantly increases the load on the telescopes used for the follow-up observations to confirm or reject candidates. Several attempts have been made at creating techniques that can pare down candidate lists without the need of additional observations. Some of these techniques involve a detailed analysis of light curve characteristics; others estimate the stellar density or some proxy thereof. In this paper, we extend upon this second approach, exploring the use of independently calculated stellar densities to identify the most promising transiting exoplanet candidates. We use a set of CoRoT candidates and the set of known transiting exoplanets to examine the potential of this approach. In particular, we note the possibilities inherent in the high-precision photometry from space missions, which can detect stellar asteroseismic pulsations from which accurate stellar densities can be extracted without additional observations.

Examination of the Attitudes of Preschool Teacher Candidates and Teacher Candidates in Other Branches towards Scientific Research in Terms of Some Variables

Science.gov (United States)

Ekici, Fatma Yasar

2017-01-01

The main objective of this study is to examine the attitudes of preschool teacher candidates and teacher candidates in other branches towards scientific research in terms of some variables. Survey method was used. The study group consists of 547 teacher candidates studying in education faculty of a private university in the spring term of…

AN ANALYSIS OF STUDENTS’ ABILITY IN USING SUB-ORDINATE CONJUNCTION IN SENTENCE WRITING OF THE GRADE XII STUDENTS OF SMA N 2 METRO ACADEMIC YEAR 2013/2014

OpenAIRE

Bambang Eko Siagianto

2017-01-01

Abstracts: Sub-ordinate conjunction is very confusing to comprehend by students. In using sub-ordinate conjunction, students usually had errors. The purpose of this research to analyze whether or not the students are able to use sub-ordinate conjunction in sentence writing, to classify kinds of sub-ordinate conjunction that was often misused by students in sentence writing The research was done at the grade XII of SMA N 2 Metro in second semester of the academic year 2013/2014. The predicted ...

Changing Perceptions of Teacher Candidates in High-Needs Schools

Science.gov (United States)

DeJarnette, Nancy K.

2016-01-01

Candidates enter teacher education programs with established beliefs about diversity and urban education. These belief systems impact decisions that teacher candidates make both now and in the future. Providing opportunities for candidates to spend quality time in an urban Professional Development School (PDS) setting with the support and guidance…

Language-invariant verb processing regions in Spanish-English bilinguals.

Science.gov (United States)

Willms, Joanna L; Shapiro, Kevin A; Peelen, Marius V; Pajtas, Petra E; Costa, Albert; Moo, Lauren R; Caramazza, Alfonso

2011-07-01

Nouns and verbs are fundamental grammatical building blocks of all languages. Studies of brain-damaged patients and healthy individuals have demonstrated that verb processing can be dissociated from noun processing at a neuroanatomical level. In cases where bilingual patients have a noun or verb deficit, the deficit has been observed in both languages. This suggests that the noun-verb distinction may be based on neural components that are common across languages. Here we investigated the cortical organization of grammatical categories in healthy, early Spanish-English bilinguals using functional magnetic resonance imaging (fMRI) in a morphophonological alternation task. Four regions showed greater activity for verbs than for nouns in both languages: left posterior middle temporal gyrus (LMTG), left middle frontal gyrus (LMFG), pre-supplementary motor area (pre-SMA), and right middle occipital gyrus (RMOG); no regions showed greater activation for nouns. Multi-voxel pattern analysis within verb-specific regions showed indistinguishable activity patterns for English and Spanish, indicating language-invariant bilingual processing. In LMTG and LMFG, patterns were more similar within than across grammatical category, both within and across languages, indicating language-invariant grammatical class information. These results suggest that the neural substrates underlying verb-specific processing are largely independent of language in bilinguals, both at the macroscopic neuroanatomical level and at the level of voxel activity patterns. Copyright © 2011 Elsevier Inc. All rights reserved.

A cohort of balanced reciprocal translocations associated with dyslexia: identification of two putative candidate genes at DYX1

DEFF Research Database (Denmark)

Buonincontri, Roberta; Bache, Iben; Silahtaroglu, Asli

2011-01-01

Dyslexia is one of the most common neurodevelopmental disorders where likely many genes are involved in the pathogenesis. So far six candidate dyslexia genes have been proposed, and two of these were identified by rare chromosomal translocations in affected individuals. By systematic re......-examination of all translocation carriers in Denmark, we have identified 16 different translocations associated with dyslexia. In four families, where the translocation co-segregated with the phenotype, one of the breakpoints concurred (at the cytogenetic level) with either a known dyslexia linkage region--at 15q21...... (DYX1), 2p13 (DYX3) and 1p36 (DYX8)--or an unpublished linkage region at 19q13. As a first exploitation of this unique cohort, we identify three novel candidate dyslexia genes, ZNF280D and TCF12 at 15q21, and PDE7B at 6q23.3, by molecular mapping of the familial translocation with the 15q21 breakpoint....