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Sample records for sleeper perccottus glenii

  1. Role of the invasive Chinese sleeper Perccottus glenii (Actinopterygii: Odontobutidae) in the distribution of fish parasites in Europe: New data and a review

    Czech Academy of Sciences Publication Activity Database

    Kvach, Yuriy; Kutsokon, Y.; Stepien, C. A.; Markovych, M.

    2016-01-01

    Roč. 71, č. 8 (2016), s. 941-951 ISSN 0006-3088 R&D Projects: GA ČR(CZ) GBP505/12/G112 Institutional support: RVO:68081766 Keywords : Chinese sleeper * enemy release hypothesis * invasive species * parasites * Perccottus glenii Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 0.759, year: 2016

  2. Predator-prey interactions between a recent invader, the Chinese sleeper (Perccottus glenii and the European pond turtle (Emys orbicularis: a case study from Lithuania

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    Vytautas Rakauskas

    2016-12-01

    Full Text Available The European pond turtle, Emys orbicularis, is a critically endangered species in most European countries. Habitat degradation and fragmentation are considered the main reasons for the decline of E. orbicularis. However, the spread of invasive species may also contribute to the disappearance of E. orbicularis populations. We examined the range overlap and predator-prey interactions between the invasive Chinese sleeper, Perccottus glenii, and E. orbicularis through controlled experiments and in field studies. Field surveys showed that both species occupied similar habitats. Predator-prey experiments suggested that newly hatched turtles are resistant to P. glenii predation. Conversely, adults of E. orbicularis consumed juvenile P. glenii even when other food sources were available. Overall, these findings suggested that E. orbicularis is not among the potential prey organisms in the diet of the invasive P. glenii, and that this fish does not directly contribute to the decline of E. orbicularis in Europe.

  3. The parasites of the invasive Chinese sleeper Perccottus glenii (Fam. Odontobutidae, with the first report of Nippotaenia mogurndae in Ukraine

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    Kvach Y.

    2013-06-01

    Full Text Available The parasites of the Asian invasive fish, Chinese sleeper Perccottus glenii, were studied in 6 localities in different parts of Ukraine. In total, 15 taxa of parasites were registered; among them were 1 species of Microsporidia, 5 species of ciliates, 2 species of cestodes, 2 species of trematodes, 2 species of nematodes, 1 species of acanthocephalan, 1 species of parasitic crustacean and 1 mollusk (glochidia. The invasive Chinese sleeper is included as a paratenic host in the life cycle of the parasites of indigenous reptiles in Europe. The non-indigenous cestode Nippotaenia mogurndae occurred in the intestine of the Chinese sleeper from the Ivachiv Reservoir (Dniester River basin. This cestode is recorded for Ukrainian fauna for the first time. In addition, 3 species of parasites were recorded in the Chinese sleeper for the first time: Nicolla skrjabini, Cosmocephalus obvelatus and Pomphorhynchus laevis. We note the low similarity among the different localities and the low parasite richness, that suggest that the parasite fauna of the Chinese sleeper in Ukraine is in transition.

  4. The expansion and occurrence of the Amur sleeper (Perccottus glenii) in eastern Slovakia

    Czech Academy of Sciences Publication Activity Database

    Koščo, J.; Lusk, Stanislav; Halačka, Karel; Lusková, Věra

    2003-01-01

    Roč. 52, č. 3 (2003), s. 329-336 ISSN 0139-7893 R&D Projects: GA AV ČR IBS6093007; GA AV ČR KSK6005114 Grant - others:VEGA(SK) 1/9209/02 Institutional research plan: CEZ:AV0Z6093917 Keywords : Perccottus glenii * invasion * Tisa drainage area Subject RIV: EH - Ecology, Behaviour Impact factor: 0.494, year: 2003 http://www.ivb.cz/folia/52/3/329-336.pdf

  5. Messages of invasive Perccottus glenii individuals eaten by an Esox lucius from the Danube Delta

    OpenAIRE

    Ilie Cătălin Telcean; Alfred-Stefan Cicort-Lucaciu

    2016-01-01

    In the stomach of a pike from the Danube Delta we have found seven Perccottus glenii individuals. Their message indicated that in the Danube Delta P. glenii has already large population. Also, it proves that in its habitats, the pike can consume numerous individuals of this invasive species. Their gut contents prove that P. glenii hunted near the shores, ingesting numerous terrestrial preys.

  6. Messages of invasive Perccottus glenii individuals eaten by an Esox lucius from the Danube Delta

    Directory of Open Access Journals (Sweden)

    Ilie Cătălin Telcean

    2016-12-01

    Full Text Available In the stomach of a pike from the Danube Delta we have found seven Perccottus glenii individuals. Their message indicated that in the Danube Delta P. glenii has already large population. Also, it proves that in its habitats, the pike can consume numerous individuals of this invasive species. Their gut contents prove that P. glenii hunted near the shores, ingesting numerous terrestrial preys.

  7. Rapid isolation of microsatellite DNAs and identification of polymorphic mitochondrial DNA regions in the fish rotan (Perccottus glenii) invading European Russia

    Science.gov (United States)

    King, Timothy L.; Eackles, Michael S.; Reshetnikov, Andrey N.

    2015-01-01

    Human-mediated translocations and subsequent large-scale colonization by the invasive fish rotan (Perccottus glenii Dybowski, 1877; Perciformes, Odontobutidae), also known as Amur or Chinese sleeper, has resulted in dramatic transformations of small lentic ecosystems. However, no detailed genetic information exists on population structure, levels of effective movement, or relatedness among geographic populations of P. glenii within the European part of the range. We used massively parallel genomic DNA shotgun sequencing on the semiconductor-based Ion Torrent Personal Genome Machine (PGM) sequencing platform to identify nuclear microsatellite and mitochondrial DNA sequences in P. glenii from European Russia. Here we describe the characterization of nine nuclear microsatellite loci, ascertain levels of allelic diversity, heterozygosity, and demographic status of P. glenii collected from Ilev, Russia, one of several initial introduction points in European Russia. In addition, we mapped sequence reads to the complete P. glenii mitochondrial DNA sequence to identify polymorphic regions. Nuclear microsatellite markers developed for P. glenii yielded sufficient genetic diversity to: (1) produce unique multilocus genotypes; (2) elucidate structure among geographic populations; and (3) provide unique perspectives for analysis of population sizes and historical demographics. Among 4.9 million filtered P. glenii Ion Torrent PGM sequence reads, 11,304 mapped to the mitochondrial genome (NC_020350). This resulted in 100 % coverage of this genome to a mean coverage depth of 102X. A total of 130 variable sites were observed between the publicly available genome from China and the studied composite mitochondrial genome. Among these, 82 were diagnostic and monomorphic between the mitochondrial genomes and distributed among 15 genome regions. The polymorphic sites (N = 48) were distributed among 11 mitochondrial genome regions. Our results also indicate that sequence reads generated

  8. The nonindigenous fish Perccottus glenii in the Tisza River drainage, Eastern Slovakia – I. part: history of invasion, habitat associations and genetic characteristics (results up to the year 2006)

    Czech Academy of Sciences Publication Activity Database

    Lusk, S.; Koščo, J.; Lusková, V.; Halačka, Karel; Mendel, Jan; Košúth, P.

    2017-01-01

    Roč. 8, č. 8 (2017), s. 127-143 ISSN 1212-1312 Institutional support: RVO:68081766 Keywords : invasive fishes * Odontobutidae * Perccottus glenii * dispersal * habitat * genetics Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology

  9. Parasite communities and infection levels of the invasive Chinese sleeper Perccottus glenii (Actinopterygii: Odontobutidae) from the Naab river basin, Germany

    Czech Academy of Sciences Publication Activity Database

    Kvach, Yuriy; Janáč, Michal; Nehring, S.; Ondračková, Markéta; Jurajda, Pavel

    2017-01-01

    Roč. 91, č. 6 (2017), s. 703-710 ISSN 0022-149X R&D Projects: GA ČR(CZ) GBP505/12/G112 Institutional support: RVO:68081766 Keywords : Amur sleeper * Baltic Sea Subject RIV: EG - Zoology OBOR OECD: Zoology Impact factor: 1.420, year: 2016

  10. Distribution of the Chinese Sleeper Perccottus glenii (Odontobutidae in fish communities of floodplain waterbodies in the Samarskaya Luka National Park (Samara Region, Russia

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    Elena V. Kirilenko

    2017-11-01

    Full Text Available The article presents data on the species composition of fish in the waterbodies of the Mordovo floodplain of the Saratov Reservoir in the territory of the Samarskaya Luka National Park. The ichthyofauna of the investigated reservoirs was studied for the first time. The species structure of fish catches in five floodplain lakes and in one channel was analysed. Typological habitat conditions in waterbodies (for example, the flowage of floodplain waterbody and its connection with the Reservoir effect the species diversity of fish. In four of the six investigated bodies of water, an alien species, the Chinese sleeper, was discovered. The biotope of the species is confined to the thickets of aquatic vegetation, regardless of the depth and place of its growth in the reservoir.

  11. Natural short sleeper

    Science.gov (United States)

    Sleep - natural short sleeper ... 7 to 9 hours of sleep each night. Short sleepers sleep less than 75% of what is normal for their age. Natural short sleepers are different from people who chronically do ...

  12. APPRAISAL OF USED WOODEN RAILWAY SLEEPER

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    SITI HAWA HAMZAH

    2008-12-01

    Full Text Available Replacement of wooden sleepers to prestressed concrete sleepers has marked as advancement in the railway sleepers industry in Malaysia. Despite superiority of these man-made composite sleepers, wooden sleepers still lead in terms of track performance qualities in particular on its natural elasticity. An initiative to investigate the degree of degradation of used wooden sleepers and the possibility of reusing them on low capacity railway track in Malaysia as a means of reducing the overall track rehabilitation cost was undertaken. Used wooden sleepers were tested according to Australian Standard, Railway Track Material, Prestressed Concrete Sleepers (AS 1085:14:2003 on Rail Seat Vertical Load Test and Centre Positive Bending Moment Test. Six wooden sleeper samples were tested under the static load until failure. Benchmarking was carried on high strength prestressed concrete sleeper, tested according to AS 1085:14:2003: Rail Seat - Positive Moment Test. The results obtained showed the maximum load that the used wooden sleepers can carry surpassed the design load of KTMB specifications and it is about 58% of high strength prestressed concrete sleeper.The maximum deflection produced by all used wooden sleepers is 20 mm showing that the sleepers maintained their elastic behaviour. Modulus of Elasticity ranging from 21 to 27 kN/mm2 of which within the standard value, indicating weathering process does not so much affect their stiffness. Most sleepers showed crack patterns propagated in the longitudinal direction. Toughness value is almost one half of the high strength prestressed concrete sleeper. This study indicates that there is a potential of reusing the wooden sleepers for light loading of the railway track. Hence, an extensive study is recommended to be carried out under fatigue loading condition.

  13. First record of the Chinese sleeper, Perccottus glenii Dybowski, 1877 (Actinopterygii: Odontobutidae) in the Dnieper Estuary, southern Ukraine (Black Sea drainage)

    Czech Academy of Sciences Publication Activity Database

    Kvach, Yuriy; Dykyy, I.; Janko, Karel

    2016-01-01

    Roč. 5, č. 4 (2016), s. 285-290 E-ISSN 2242-1300 R&D Projects: GA ČR(CZ) GBP505/12/G112; GA ČR GA13-12580S Institutional support: RVO:68081766 ; RVO:67985904 Keywords : invasive species * new finding * Dnieper Estuary * Ukraine Subject RIV: EH - Ecology, Behaviour Impact factor: 0.835, year: 2016 http://www.reabic.net/journals/bir/2016/4/BIR_2016_Kvach_etal.pdf

  14. Time-Dependent Topology of Railway Prestressed Concrete Sleepers

    Science.gov (United States)

    Li, Dan; Ngamkhanong, Chayut; Kaewunruen, Sakdirat

    2017-10-01

    The railway sleepers are very important component of railway track structure. The sleepers can be manufactured by using timber, concrete, steel or other engineered materials. Nowadays, prestressed concrete has become most commonly used type of sleepers. Prestressed concrete sleepers have longer life-cycle and lower maintenance cost than reinforced concrete sleepers. They are expected to withstand high dynamic loads and harsh environments. However, durability and long-term performance of prestressed concrete sleepers are largely dependent on creep and shrinkage responses. This study investigates the long-term behaviours of prestressed concrete sleepers and proposes the shortening and deflection diagrams. Comparison between design codes of Eurocode 2 and AS3600-2009 provides the insight into the time-dependent performance of prestressed concrete sleepers. The outcome of this paper will improve the rail maintenance and inspection criteria in order to establish appropriate sensible remote track condition monitor network in practice.

  15. Sleep Characteristics of Self-Reported Long Sleepers

    Science.gov (United States)

    Patel, Sanjay R.; Blackwell, Terri; Ancoli-Israel, Sonia; Stone, Katie L.

    2012-01-01

    Background: Self-reported long habitual sleep durations (≥ 9 h per night) consistently predict increased mortality. We compared objective sleep parameters of self-reported long versus normal duration sleepers to determine whether long sleepers truly sleep more or have an underlying sleep abnormality. Methods: Older men participating in the Osteoporotic Fractures in Men Study (MrOS) were recruited for a comprehensive sleep assessment, which included wrist actigraphy, overnight polysomnography (PSG), and a question about usual nocturnal sleep duration. Results: Of the 3134 participants (mean age 76.4 ± 5.6; 89.9% Caucasian), 1888 (60.2%) reported sleeping 7-8 h (normal sleepers) and 174 (5.6%) reported ≥ 9 h (long sleepers). On actigraphy, long sleepers spent on average 63.0 min more per night in bed (P sleep stage distribution did not differ. After adjusting for differences in demographics, comorbidities, and medication usage, self-reported long sleepers continued to spend more time in bed and sleep more, based on both actigraphy and PSG. Each additional 30 min in bed or asleep as measured by actigraphy increased the odds of being a self-reported long-sleeper 1.74-fold and 1.33-fold, respectively (P sleep disorders. Citation: Patel SR; Blackwell T; Ancoli-Israel S; Stone KL. Sleep characteristics of self-reported long sleepers. SLEEP 2012;35(5):641-648. PMID:22547890

  16. Damage Detection in Railway Prestressed Concrete Sleepers using Acoustic Emission

    Science.gov (United States)

    Clark, A.; Kaewunruen, S.; Janeliukstis, R.; Papaelias, M.

    2017-10-01

    Prestressed concrete sleepers (or railroad ties) are safety-critical elements in railway tracks that distribute the wheel loads from the rails to the track support system. Over a period of time, the concrete sleepers age and deteriorate in addition to experiencing various types of static and dynamic loading conditions, which are attributable to train operations. In many cases, structural cracks can develop within the sleepers due to high intensity impact loads or due to poor track maintenance. Often, cracks of sleepers develop and present at the midspan due to excessive negative bending. These cracks can cause broken sleepers and sometimes called ‘center bound’ problem in railway lines. This paper is the world first to present an application of non-destructive acoustic emission technology for damage detection in railway concrete sleepers. It presents experimental investigations in order to detect center-bound cracks in railway prestressed concrete sleepers. Experimental laboratory testing involves three-point bending tests of four concrete sleepers. Three-point bending tests correspond to a real failure mode, when the loads are not transferred uniformly to the ballast support. It is observed that AE sensing provides an accurate means for detecting the location and magnitude of cracks in sleepers. Sensor location criticality is also highlighted in the paper to demonstrate the reliability-based damage detection of the sleepers.

  17. Performance of Railway Sleepers with Holes under Impact Loading

    Science.gov (United States)

    Lim, Chie Hong; Kaewunruen, Sakdirat; Mlilo, Nhlanganiso

    2017-12-01

    Prestressed concrete sleepers are essential structural components of railway track structures, with the purpose of redistributing wheel loads from the rails to the ground. To facilitate cables and signalling equipment, holes are often generated in these prestressed concrete sleepers. However, the performance of these sleepers under impact loading may be a concern with the addition of these holes. Numerical modelling using finite element analysis (FEA) is an ideal tool that enables static and dynamic simulation and can perform analyses of basic/advanced linear and nonlinear problems, without incurring a huge cost in resources like standard experimental test methods would. This paper will utilize the three-dimensional FE modelling software ABAQUS to investigate the behaviour of the prestressed concrete sleepers with holes of varying sizes upon impact loading. To obtain the results that resemble real-life behaviour of the sleepers under impact loading, the material properties, element types, mesh sizes, contact and interactions and boundary conditions will be defined as accurately as possible. Both Concrete Damaged Plasticity (CDP) and Brittle Cracking models will be used in this study. With a better understanding of how the introduction of holes will influence the performance of prestressed sleepers under impact loading, track and railway engineers will be able to generate them in prestressed concrete sleepers without compromising the sleepers’ performance during operation

  18. Impact analyses for negative flexural responses (hogging) in railway prestressed concrete sleepers

    International Nuclear Information System (INIS)

    Kaewunruen, S; Ishida, T; Remennikov, AM

    2016-01-01

    By nature, ballast interacts with railway concrete sleepers in order to provide bearing support to track system. Most train-track dynamic models do not consider the degradation of ballast over time. In fact, the ballast degradation causes differential settlement and impact forces acting on partial and unsupported tracks. Furthermore, localised ballast breakages underneath railseat increase the likelihood of centrebound cracks in concrete sleepers due to the unbalanced support under sleepers. This paper presents a dynamic finite element model of a standard-gauge concrete sleeper in a track system, taking into account the tensionless nature of ballast support. The finite element model was calibrated using static and dynamic responses in the past. In this paper, the effects of centre-bound ballast support on the impact behaviours of sleepers are highlighted. In addition, it is the first to demonstrate the dynamic effects of sleeper length on the dynamic design deficiency in concrete sleepers. The outcome of this study will benefit the rail maintenance criteria of track resurfacing in order to restore ballast profile and appropriate sleeper/ballast interaction. (paper)

  19. Impact analyses for negative flexural responses (hogging) in railway prestressed concrete sleepers

    Science.gov (United States)

    Kaewunruen, S.; Ishida, T.; Remennikov, AM

    2016-09-01

    By nature, ballast interacts with railway concrete sleepers in order to provide bearing support to track system. Most train-track dynamic models do not consider the degradation of ballast over time. In fact, the ballast degradation causes differential settlement and impact forces acting on partial and unsupported tracks. Furthermore, localised ballast breakages underneath railseat increase the likelihood of centrebound cracks in concrete sleepers due to the unbalanced support under sleepers. This paper presents a dynamic finite element model of a standard-gauge concrete sleeper in a track system, taking into account the tensionless nature of ballast support. The finite element model was calibrated using static and dynamic responses in the past. In this paper, the effects of centre-bound ballast support on the impact behaviours of sleepers are highlighted. In addition, it is the first to demonstrate the dynamic effects of sleeper length on the dynamic design deficiency in concrete sleepers. The outcome of this study will benefit the rail maintenance criteria of track resurfacing in order to restore ballast profile and appropriate sleeper/ballast interaction.

  20. Impact capacity reduction in railway prestressed concrete sleepers with vertical holes

    Science.gov (United States)

    Ngamkhanong, Chayut; Li, Dan; Kaewunruen, Sakdirat

    2017-09-01

    Railway prestressed concrete sleepers (or railroad ties) are principally designed in order to carry wheel loads from the rails to the ground as well as to secure rail gauge for dynamic safe movements of trains. In spite of the most common use of the prestressed concrete sleepers in railway tracks, the concrete sleepers are often modified on construction sites to fit in other systems such as cables, signalling gears, drainage pipes, etc. This is because those signalling, fibre optic, equipment cables are often damaged either by ballast corners or by tamping machine. It is thus necessary to modify concrete sleepers to cater cables internally so that the cables or drainage pipes would not experience detrimental or harsh environments. Accordingly, this study will extend from the previous study into the design criteria of holes and web openings. This paper will highlight structural capacity of concrete sleepers under dynamic transient loading. The modified compression field theory for ultimate strength design of concrete sleepers will be highlighted in this study. The outcome of this study will improve the understanding into dynamic behavior of prestressed concrete sleepers with vertical holes. The insight will enable predictive track maintenance regime in railway industry.

  1. Impact Capacity Reduction in Railway Prestressed Concrete Sleepers with Surface Abrasions

    Science.gov (United States)

    Ngamkhanong, Chayut; Li, Dan; Kaewunruen, Sakdirat

    2017-10-01

    Railway sleepers (also called ‘railroad tie’ in North America) embedded in ballasted railway tracks are a main part of railway track structures. Its important role is to transfer the loads evenly from the rails to a wider area of ballast bed and to secure rail gauge and enable safe passages of rolling stocks. By nature, railway infrastructure is nonlinear, evidenced by its behaviours, geometry and alignment, wheel-rail contact and operational parameters such as tractive efforts. Based on our critical review, the dynamic behaviour of railway sleepers has not been fully investigated, especially when the sleepers are deteriorated by excessive wears. In fact, the ballast angularity causes differential abrasions on the soffit or bottom surface of sleepers (especially at railseat zone). Furthermore, in sharp curves and rapid gradient change, longitudinal and lateral dynamics of rails increase the likelihood of railseat abrasions in concrete sleepers due to the unbalanced loading conditions. This paper presents a structural capacity of concrete sleepers under dynamic transient loading. The modified compression field theory for ultimate strength design of concrete sleepers under impact loading will be highlighted in this study. The influences of surface abrasions, including surface abrasion and soffit abrasion, on the dynamic behaviour of prestressed concrete sleepers, are firstly highlighted. The outcome of this study will improve the rail maintenance and inspection criteria in order to establish appropriate and sensible remote track condition monitoring network in practice. Moreover, this study will also improve the understanding of the fundamental dynamic behaviour of prestressed concrete sleepers with surface abrasions. The insight into these behaviours will not only improve safety and reliability of railway infrastructure but will enhance the structural safety of other concrete structures.

  2. Ichthyofauna species of the upper Kaniv reservoir and mouth area of the Desna River

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    Y. M. Sytnik

    2012-07-01

    Full Text Available It was studied the fish species of the upper part of Kaniv reservoir (Kyiv water area and the mouth area of the Desna River. The found and preceding data of ichthyological research were compared. The changes in the fish population were analyzed. Two new invasive alien fish species were discovered in the Kaniv reservoir and Desna River: Amur sleeper (Perccotus glenii and Stone moroco (Pseudorasdora parva. Generally the ichthyofauna composition of these water bodies was supplemented with seven unmarketable and dirt species.

  3. The presence of a perseverative iterative style in poor vs. good sleepers.

    Science.gov (United States)

    Barclay, N L; Gregory, A M

    2010-03-01

    Catastrophizing is present in worriers and poor sleepers. This study investigates whether poor sleepers possess a 'perseverative iterative style' which predisposes them to catastrophize any topic, regardless of content or affective valence, a style previously found to occur more commonly in worriers as compared to others. Poor (n=23) and good sleepers (n=37) were distinguished using the Pittsburgh Sleep Quality Index (PSQI), from a sample of adults in the general population. Participants were required to catastrophize 2 topics: worries about sleep, and a current personal worry; and to iterate the positive aspects of a hypothetical topic. Poor sleepers catastrophized/iterated more steps to a greater extent than good sleepers to these three interviews, (F(1, 58)=7.35, ptopics, suggesting that anxiety may mediate some of the association between catastrophizing and sleep. However there was still a tendency for poor sleepers to iterate more steps to the 'hypothetical' topic, after controlling for anxiety and worry, which also suggests that poor sleepers possess a cognitive style which may predispose them to continue iterating consecutive steps to open-ended tasks regardless of anxiety and worry. Future research should examine whether the presence of this cognitive style is significant in leading to or maintaining insomnia.

  4. Static and dynamic behaviours of railway prestressed concrete sleepers with longitudinal through hole

    Science.gov (United States)

    Ngamkhanong, C.; Kaewunruen, S.; Remennikov, A. M.

    2017-10-01

    As the crosstie beam in railway track systems, the prestressed concrete sleepers (or railroad ties) are principally designed in order to carry wheel loads from the rails to the ground. Their design takes into account static and dynamic loading conditions. It is evident that prestressed concrete has played a significant role as to maintain the high endurance of the sleepers under low to moderate repeated impact loads. In spite of the most common use of the prestressed concrete sleepers in railway tracks, there have always been many demands from rail engineers to improve serviceability and functionality of concrete sleepers. For example, signalling, fibre optic, equipment cables are often damaged either by ballast corners or by tamping machine. There has been a need to re-design concrete sleeper to cater cables internally so that they would not experience detrimental or harsh environments. Accordingly, this study will investigate the effects of through hole or longitudinal hole on static and dynamic behaviours of concrete sleepers under rail shock loading. The modified compression field theory for ultimate strength design of concrete sleepers will be highlighted in this study. The outcome of this study will enable the new design and calculation methods for prestressed concrete sleepers with holes and web opening that practically benefits civil, track and structural engineers in railway industry.

  5. Influence of Surface Abrasion on Creep and Shrinkage of Railway Prestressed Concrete Sleepers

    Science.gov (United States)

    Li, Dan; Ngamkhanong, Chayut; Kaewunruen, Sakdirat

    2017-10-01

    Ballasted railway track is very suitable for heavy-rail networks because of its many superior advantages in design, construction, short- and long-term maintenance, sustainability, and life-cycle cost. The sleeper, which supports rail and distributes loads from rail to ballast, is a very important component of rail track system. Prestressed concrete is very popular used in manufacturing sleepers. Therefore, improved knowledge about design techniques for prestressed concrete (PC) sleepers has been developed. However, the ballast angularity causes differential abrasions on the soffit or bottom surface of sleepers. Furthermore, in sharp curves and rapid gradient change, longitudinal and lateral dynamics of rails increase the likelihood of abrasions in concrete sleepers. This paper presents a comparative investigation using a variety of methods to evaluate creep and shrinkage effects in railway prestressed concrete sleepers. The outcome of this study will improve the material design, which is very critical to the durability of railway track components.

  6. A Review on the Development of New Materials for Construction of Prestressed Concrete Railway Sleepers

    Science.gov (United States)

    Raj, Anand; Nagarajan, Praveen; Shashikala, A. P.

    2018-03-01

    Railways form the backbone of all economies, transporting goods, and passengers alike. Sleepers play a pivotal role in track performance and safety in rail transport. This paper discusses in brief about the materials that have been used in making sleepers in the early stages of railways. Extensive studies have been carried out on the static, dynamic and impact analysis of prestressed sleepers all around the globe. It has been shown that majority of the sleepers do not last till their expected design life resulting in massive replacement and repair cost. The primary reasons leading to the failure of sleepers have been summarised. This article also highlights the use of new materials developed recently for the construction of prestressed concrete sleepers to improve the performance and life of railway sleepers. Use of geopolymer concrete and steel fibre reinforced concrete, assist in the reduction of flexural cracking, whereas rubber concrete enhances the impact resistance of concrete by three folds. This paper presents a review of state of the art of new materials for railway sleepers.

  7. Influence of vertical holes on creep and shrinkage of railway prestressed concrete sleepers

    Science.gov (United States)

    Li, Dan; Ngamkhanong, Chayut; Kaewunruen, Sakdirat

    2017-09-01

    Railway prestressed concrete sleepers (or railroad ties) must successfully perform two critical duties: first, to carry wheel loads from the rails to the ground; and second, to secure rail gauge for dynamic safe movements of trains. The second duty is often fouled by inappropriate design of the time-dependent behaviors due to their creep, shrinkage and elastic shortening responses of the materials. In addition, the concrete sleepers are often modified on construction sites to fit in other systems such as cables, signalling gears, drainage pipes, etc. Accordingly, this study is the world first to investigate creep and shrinkage effects on the railway prestressed concrete sleepers with vertical holes. This paper will highlight constitutive models of concrete materials within the railway sleepers under different environmental conditions over time. It will present a comparative investigation using a variety of methods to evaluate shortening effects in railway prestressed concrete sleepers. The outcome of this study will improve material design, which is very critical to the durability of railway track components.

  8. Gamma-ray backscatter applied to the on-line location of termite-damaged railway sleepers

    International Nuclear Information System (INIS)

    Fookes, R.A.; Watt, J.S.; Seatonberry, B.W.; Davison, A.; Greig, R.A.; Lowe, H.W.G.; Abbott, A.C.

    1978-01-01

    A radioisotope system has been developed to locate groups of termite-damaged sleepers during continuous scans of a railway track. It depends on measuring the intensities of collimated beams of 137 Cs γ-rays backscattered from within the sleeper. The detected intensity varies with the amount of termite damage (i.e. voidage). Variations in intensity caused by changes in the density of sound sleepers are minimised by the geometrical arrangement of source, shields and detector. The Atomic Voidage Detector (AVD) has been tested in field trials on the Newman to Port Hedland railway, Western Australia. Four separate groups of termite-damaged sleepers were located and examined. The lower limit of detectable voidage depends mainly on the scanning speed and distribution of voids within the sleeper, and is very approximately 8% voidage at 10.7 km/h and 5% at 2.7 km/h. (author)

  9. BEARING CAPACITY OF A HORIZONTALLY LOADED SINGLE PILE SUPPORT WITH SLEEPERS

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    Buslov Anatoliy Semenovich

    2015-09-01

    Full Text Available The supports of a overhead wiring used in transport take up substantial loads both because of wires and constructions holding them and wind, dynamic and other extraordinary impacts. In case of using single-member piles a question about their stability appears. For this reason different sleepers constructions are used. In order to improve the bearing capacity of horizontally loaded single pile supports of the contact systems used in urban, road and rail transport, power lines, etc.., it is recommended to use sleepers as horizontally laid under the ground in the depth of support beams. The calculation methods for different support sleepers of different lengths and cross sections are not well investigated. The proposed calculation method allows determining the carrying capacity of horizontally loaded bearings with soil pieces of different structural dimensions and their location in the soil, which allows choosing the best option for cost and material consumption. The calculations offered by the authors prove the efficiency of sleepers use in order to increase the bearing capacity of horizontally loaded piles and the possibility to chose their size.

  10. SQUEEZING EFFECT OF RAIL LOADED BY SEMI-SLEEPERS HAVING L-SHAPED CROSS-SECTION

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    V. N. Sukhodoev

    2015-01-01

    Full Text Available The paper considers a problem on introduction of a conception and regularities of “squeezing effect of a rail loaded non centrally by semi-sleepers having L-shaped cross-section” exemplified by belt-type tramway. Its advantages are ensured by doubled non centrally loaded foundations these are semi-sleepers. Semi-sleeper of L-shape cross-section is a lever of L-shape form, transforming a vertical load into horizontal ones and foundation squeezing. Properties of two semi-sleepers being doubled, orientated to each other and non centrally loaded have been used in order to create a positive effect. A horizontal force creates squeezing and it is revealed as a component of a vertical load during displacements which functionally depend on foundation squeezing. These dependences demonstrate that strength and deformation properties of earth foundation of vertical direction are used for creation of horizontal properties of sleeper vertical shoulder.The paper studies mechanics pertaining to a squeezing effect of a rail loaded by semi-sleepers having L-shaped cross-section. It has been established that the rail squeezing effect results from squeezing process executed in two mutually perpendicular directions (reduction of cross-sectional area by load of a rail wheel with spacers if they are set inside of a sleeper-mechanism on an elastic foundation.Methodology for calculation of parameters on the rail reduction effect is considered as a tool for handling of applied problems on belt-type tramways. Results of the proposed rail reduction effect in problem statement for elastic conditions, with unchanged cross-sectional dimension of a rail line and introduction of correction ratio coefficients due to new initial load data have recommended for practical application as reliable values.The paper has revealed a proportional dependence of the rail reduction effect according to strength on the resultant value of reaction pressure, eccentricity difference of the

  11. A three-phase epidemiological study of short and long sleepers in a middle-aged Chinese population: prevalence and characteristics

    International Nuclear Information System (INIS)

    Hao, Y.L.; Zhang, B.; Jia, F.J.; Li, X.L.; Tang, Y.; Ren, Y.Z.; Liu, W.H.

    2014-01-01

    Epidemiological studies of short and long sleepers have not been conducted previously. We collected socioeconomic, psychological, and polysomnographic characteristics of 6501 parents (3252 men and 3249 women) of 4036 primary school children in Guangzhou city. The study data were collected in three phases. The overall prevalence of short (5 h or less) and long (10 h or more) sleep duration was 0.52 and 0.64%, respectively. Long sleepers had higher Eysenck Personality Questionnaire neuroticism scores [odds ratio (OR)=1.224, 95% confidence interval (CI)=1.047-1.409] and lower education levels (OR=0.740, 95%CI=0.631-0.849) than short sleepers. In the polysomnographic assessment, short, long, and normal sleepers (7-8 h) shared similar durations of Stage 3 sleep (short=25.7±10.7, long=20.3±7.9, and normal=28.0±12.8 min, F=1.402, P=0.181). In daytime multiple sleep latency tests, short sleepers (10/19, 52.6%) were more prone to have a short sleep latency (≤8 min) than long sleepers (2/23, 8.7%). In addition to different sleep durations, neuroticism might also contribute to differences between short and long sleepers in social achievements. Stage 3 sleep might be essential for humans. The short sleep latency (≤8 min) of short sleepers in multiple sleep latency tests should be interpreted cautiously, since it was of the same severity as required for a diagnosis of narcolepsy or idiopathic hypersomnia

  12. A three-phase epidemiological study of short and long sleepers in a middle-aged Chinese population: prevalence and characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Hao, Y.L. [Department of Human Anatomy, Guangzhou Medical University, Guangzhou, China, Department of Human Anatomy, Guangzhou Medical University, Guangzhou (China); Zhang, B.; Jia, F.J.; Li, X.L.; Tang, Y. [Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Mental Health Centre, Guangzhou, China, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Mental Health Centre, Guangzhou (China); Ren, Y.Z. [Zhongshan The Third People' s Hospital, Zhongshan, China, Zhongshan The Third People' s Hospital, Zhongshan (China); Liu, W.H. [Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Mental Health Centre, Guangzhou, China, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Mental Health Centre, Guangzhou (China)

    2014-02-17

    Epidemiological studies of short and long sleepers have not been conducted previously. We collected socioeconomic, psychological, and polysomnographic characteristics of 6501 parents (3252 men and 3249 women) of 4036 primary school children in Guangzhou city. The study data were collected in three phases. The overall prevalence of short (5 h or less) and long (10 h or more) sleep duration was 0.52 and 0.64%, respectively. Long sleepers had higher Eysenck Personality Questionnaire neuroticism scores [odds ratio (OR)=1.224, 95% confidence interval (CI)=1.047-1.409] and lower education levels (OR=0.740, 95%CI=0.631-0.849) than short sleepers. In the polysomnographic assessment, short, long, and normal sleepers (7-8 h) shared similar durations of Stage 3 sleep (short=25.7±10.7, long=20.3±7.9, and normal=28.0±12.8 min, F=1.402, P=0.181). In daytime multiple sleep latency tests, short sleepers (10/19, 52.6%) were more prone to have a short sleep latency (≤8 min) than long sleepers (2/23, 8.7%). In addition to different sleep durations, neuroticism might also contribute to differences between short and long sleepers in social achievements. Stage 3 sleep might be essential for humans. The short sleep latency (≤8 min) of short sleepers in multiple sleep latency tests should be interpreted cautiously, since it was of the same severity as required for a diagnosis of narcolepsy or idiopathic hypersomnia.

  13. A three-phase epidemiological study of short and long sleepers in a middle-aged Chinese population: prevalence and characteristics

    Directory of Open Access Journals (Sweden)

    Y.L. Hao

    2014-02-01

    Full Text Available Epidemiological studies of short and long sleepers have not been conducted previously. We collected socioeconomic, psychological, and polysomnographic characteristics of 6501 parents (3252 men and 3249 women of 4036 primary school children in Guangzhou city. The study data were collected in three phases. The overall prevalence of short (5 h or less and long (10 h or more sleep duration was 0.52 and 0.64%, respectively. Long sleepers had higher Eysenck Personality Questionnaire neuroticism scores [odds ratio (OR=1.224, 95% confidence interval (CI=1.047-1.409] and lower education levels (OR=0.740, 95%CI=0.631-0.849 than short sleepers. In the polysomnographic assessment, short, long, and normal sleepers (7-8 h shared similar durations of Stage 3 sleep (short=25.7±10.7, long=20.3±7.9, and normal=28.0±12.8 min, F=1.402, P=0.181. In daytime multiple sleep latency tests, short sleepers (10/19, 52.6% were more prone to have a short sleep latency (≤8 min than long sleepers (2/23, 8.7%. In addition to different sleep durations, neuroticism might also contribute to differences between short and long sleepers in social achievements. Stage 3 sleep might be essential for humans. The short sleep latency (≤8 min of short sleepers in multiple sleep latency tests should be interpreted cautiously, since it was of the same severity as required for a diagnosis of narcolepsy or idiopathic hypersomnia.

  14. Sleep-related attentional bias in poor versus good sleepers is independent of affective valence.

    Science.gov (United States)

    Barclay, Nicola L; Ellis, Jason G

    2013-08-01

    Contradictory evidence exists relating to the presence of an attention bias to sleep-related stimuli in poor sleepers/insomnia using the emotional Stroop task (EST). These inconsistencies may be due to methodological issues related to the affective valence of the sleep-related stimuli. Thus, individuals may attend differentially to sleep-related stimuli not because of their 'sleep' properties, but their negativity. The current study addresses this by controlling the affective valence of sleep-related words. A total of 107 participants [mean age = 33.22 years, standard deviation (SD) = 12.31 years; 61.7% female] were recruited during an evening event at the Newcastle Science Festival. Participants completed the Pittsburgh Sleep Quality Index (PSQI) and a computerized EST containing 20 non-affective sleep-related, 20 neutral and 20 negatively valenced threat words. Good and poor sleepers were categorized using the PSQI. There were no significant differences between groups on response latency to sleep-related words (t(105) = -0.30, P = 0.76). However, the interaction between good versus poor sleepers and word-type on response latency was significant (F(2,210) = 3.06, P sleep-related words (mean = 723.35, SD = 172.55) compared to threat words (mean = 694.63, SD = 162.17) than good sleepers (mean = 713.20, SD = 166.32; and mean = 716.65, SD = 181.14). The results demonstrate the presence of an attention bias towards sleep-related stimuli compared to threat stimuli in poor sleepers. Accordingly, poor sleepers may be consumed by stimuli relevant to their specific difficulties, as well as being more highly attuned to negative cues that signal anxious states. Thus, the present research suggests that there are two opposing forces at play: one which facilitates performance (non-specific threats) and one which hinders performance (personally relevant threats). © 2013 European Sleep Research Society.

  15. Essential and non-essential element concentrations in two sleeper shark species collected in arctic waters

    Energy Technology Data Exchange (ETDEWEB)

    McMeans, Bailey C. [Great Lakes Institute for Environmental Research, University of Windsor, 401 Sunset Avenue, Windsor, ON, N9B 3P4 (Canada); Borga, Katrine [Norwegian Institute for Water Research, P.O. Box 173, Kjelsas, N-0411 Oslo (Norway); Bechtol, William R. [Alaska Department of Fish and Game, Division of Commercial Fisheries, Anchorage, AK 99518-1599 (United States); Higginbotham, David [Warnell School of Forestry and Natural Resources, University of Georgia, Athens, GA 30602-2152 (United States); Fisk, Aaron T. [Great Lakes Institute for Environmental Research, University of Windsor, 401 Sunset Avenue, Windsor, ON, N9B 3P4 (Canada)]. E-mail: afisk@uwindsor.ca

    2007-07-15

    A number of elements/metals have increased in arctic biota and are of concern due to their potential toxicity. Most studies on elements in the Arctic have focused on marine mammals and seabirds, but concentrations in the Greenland shark (Somniosus microcephalus) and Pacific sleeper shark (Somniosus pacificus), the only two shark species known to regularly inhabit arctic waters, have never been reported. To address this data gap, concentrations and patterns of 25 elements were analyzed in liver of Greenland sharks collected about Cumberland Sound (n = 24) and Pacific sleeper sharks collected about Prince William Sound (n = 14). Several non-essential elements differed between species/locations, which could suggest geographical exposure differences or ecological (e.g., diet) differences between the species. Certain essential elements also differed between the two sleeper sharks, which may indicate different physiological requirements between these closely related shark species, although information on such relationships are lacking for sharks and fish. - Patterns of essential and non-essential elements provide insight into sleeper shark biology and physiology.

  16. Essential and non-essential element concentrations in two sleeper shark species collected in arctic waters

    International Nuclear Information System (INIS)

    McMeans, Bailey C.; Borga, Katrine; Bechtol, William R.; Higginbotham, David; Fisk, Aaron T.

    2007-01-01

    A number of elements/metals have increased in arctic biota and are of concern due to their potential toxicity. Most studies on elements in the Arctic have focused on marine mammals and seabirds, but concentrations in the Greenland shark (Somniosus microcephalus) and Pacific sleeper shark (Somniosus pacificus), the only two shark species known to regularly inhabit arctic waters, have never been reported. To address this data gap, concentrations and patterns of 25 elements were analyzed in liver of Greenland sharks collected about Cumberland Sound (n = 24) and Pacific sleeper sharks collected about Prince William Sound (n = 14). Several non-essential elements differed between species/locations, which could suggest geographical exposure differences or ecological (e.g., diet) differences between the species. Certain essential elements also differed between the two sleeper sharks, which may indicate different physiological requirements between these closely related shark species, although information on such relationships are lacking for sharks and fish. - Patterns of essential and non-essential elements provide insight into sleeper shark biology and physiology

  17. (SNP) markers for the Chinese black sleeper, Bostrychus sinensis

    African Journals Online (AJOL)

    ajl yemi

    2011-04-25

    Apr 25, 2011 ... Polynesia, north to Japan and south to Australia (Kottelat et al., 1993; Masuda ... developed the first set of SNP markers for Chinese black sleeper which can ... Then, the. 44 primer pairs were designed based on all the cloning.

  18. Detection of Ballast Damage by In-Situ Vibration Measurement of Sleepers

    Science.gov (United States)

    Lam, H. F.; Wong, M. T.; Keefe, R. M.

    2010-05-01

    Ballasted track is one of the most important elements of railway transportation systems worldwide. Owing to its importance in railway safety, many monitoring and evaluation methods have been developed. Current railway track monitoring systems are comprehensive, fast and efficient in testing railway track level and alignment, rail gauge, rail corrugation, etc. However, the monitoring of ballast condition still relies very much on visual inspection and core tests. Although extensive research has been carried out in the development of non-destructive methods for ballast condition evaluation, a commonly accepted and cost-effective method is still in demand. In Hong Kong practice, if abnormal train vibration is reported by the train operator or passengers, permanent way inspectors will locate the problem area by track geometry measurement. It must be pointed out that visual inspection can only identify ballast damage on the track surface, the track geometry deficiencies and rail twists can be detected using a track gauge. Ballast damage under the sleeper loading area and the ballast shoulder, which are the main factors affecting track stability and ride quality, are extremely difficult if not impossible to be detected by visual inspection. Core test is a destructive test, which is expensive, time consuming and may be disruptive to traffic. A fast real-time ballast damage detection method that can be implemented by permanent way inspectors with simple equipment can certainly provide valuable information for engineers in assessing the safety and riding quality of ballasted track systems. The main objective of this paper is to study the feasibility in using the vibration characteristics of sleepers in quantifying the ballast condition under the sleepers, and so as to explore the possibility in developing a handy method for the detection of ballast damage based on the measured vibration of sleepers.

  19. Comparison of good and poor sleepers : stress and life satisfaction of university athletes

    OpenAIRE

    Litwic-Kaminska, Kamila

    2017-01-01

    The aim of the present study was to compare differences in level of perceived stress, type of stress appraisal and life satisfaction between university athletes who declare problems with sleep (Poor Sleepers, PS, n = 72) and those without problems (Good Sleepers, GS, n = 105). In preliminary analyses the PS and GS were compared for group homogeneity with (a) the Chi-Square test for gender and type of sport, and (b) the Mann-Whitney U test for practice time and weekly frequency of trainings. I...

  20. Utilization of bagasse and coconut fibers waste as fillers of sandwich composite for bridge railway sleepers

    Science.gov (United States)

    Soehardjo, K. A.; Basuki, A.

    2017-07-01

    The bridge railway sleepers is an essential component in the construction of railways, as the foundation of the rail support in order to withstand the load a train that runs above it. Sleepers used in bridge construction are expected to have a longer service life, lighter weight and durable so that can be used more efficient. This research was carried out to create a model of bridges railway sleepers made of sandwich structured composite from fiber glass, epoxy resin with fillers waste of bagasse (sugar cane pulp mill) or coconut fiberboard (copra industry) that using polyurethane as an adhesive. The process of making was conditioned for small and medium industrial applications. Railway sleepers’ specifications adapted to meet the requirements of end user. The process steps in this research include; lay-up fiberglass combined with bagasse/coconut fiberboard (as fillers), gluing with epoxy resin, molded it with pressure to be solid, curing after solidification process. The specimens of composite, bagasse and coconut fiber board were tested for tensile and compressive strength. The prototype were tested of mechanical test: flexural moment test to the stand rail, flexural moment test to the middle of the sleepers and tensile strength test on one side of the sleepers, in accordance to SNI 11-3388-1994 Method testing of single block concrete sleepers and bearing single rail fastening systems. The results of mechanical testing all variations meet the technical specifications of end user such as test results for flexural moment on all prototypes, after load test, there is no visible crack. While in the tensile strength test, it seem the prototype with coconut fiberboard filler, shows better performance than bagasse fiberboard filler, the decisions is just depended on techno economic and lifetime.

  1. (SNP) markers for the Chinese black sleeper, Bostrychus sinensis

    African Journals Online (AJOL)

    ajl yemi

    2011-04-25

    Apr 25, 2011 ... The Chinese black sleeper, Bostrychus sinensis. Lacepede 1801, occurs from the northern Indian Ocean coast, reaching east to the Pacific, Melanesia and ... specificity, spawns in burrow and shows behavior of guarding eggs. These characteristics not only influence their expansion capability, but make ...

  2. (SNP) markers for the Chinese black sleeper, Bostrychus sinensis

    African Journals Online (AJOL)

    We characterized 11 single nucleotide ploymorphism (SNP) markers for the Chinese black sleeper, Bostrychus sinensis. These markers were isolated from a genomic library and tested in ten geographically distant individuals of B. sinensis. Polymorphisms of these SNP loci were assessed using a wild population including ...

  3. STRUCTURAL CHARACTERISTIC OF ICHTHYOPLANKTON IN A SMALL RIVER FLOWING WITHIN A BAR PLAIN OF THE DNIPRO RIVER

    Directory of Open Access Journals (Sweden)

    I. Abramiuk

    2017-09-01

    Full Text Available Purpose. Using as an example of a small river, which flows through a bar plain of the Dnipro, to study species composition of the littoral ichthyoplankton, dynamics of its structure during the season and its diversity in different parts of the river. Methodology. The littoral ichthyoplankton was investigated during four seasons of 2011-2014 on the Vita river, a right tributary of the Dnipro affected by the operation of Kaniv HPP. The research covered the main channel, a permanent backwater connected with the channel, as well as temporarily flooded areas of the floodplain and separated from the channel oxbow lakes. Samples were collected with standard sweep nets and Bagenal buoyant nets. Identification of young fish was carried out under binocular microscope MBS-9. Early life stages of larvae were determined according to the system of V. Vasnetsov. Species diversity of ichthyoplankton was assessed by the Shannon index. Findings. The littoral ichthyoplankton during May-July mostly consisted of limnophilic fish larvae belonging to a family Cyprinidae. In the river channel and the backwater at the beginning of the period the larvae of roach (Rutilus rutilus prevailed, later they were substituted by larvae of more thermophilic species, among which the rudd (Scardinius erythrophthalmus was the most abundant. In the oxbow lakes and temporarily flooded areas in spring the coastal ichthyoplankton was mainly structured by larvae of Carassius sp. and the rudd, in summer the larvae assemblages of oxbow lakes were quantitatively dominated by the sunbleak (Leucaspius delineatus. In areas covered with vegetation the larvae of invasive Chinese sleeper (Perccottus glenii were firstly found. Rheophilic species among young fish were absent, which indicates unfavorable conditions for their spawning at present hydrologic regime of the river. Originality. For the first time the coastal communities of early young fish in a small tributary of the Dnipro were

  4. Research on the Numerical Simulation of Sleeper in the Pipeline Global Buckling Controlling Practice

    Directory of Open Access Journals (Sweden)

    Liu Wen-Bin

    2017-01-01

    Full Text Available This paper analyzed the lateral buckling of pipelines located in Western Africa with ABAQUS software. The application of sleepers in practice is explored to guide the pipeline buckling controlling design.

  5. What Sways People's Judgment of Sleep Quality? A Quantitative Choice-Making Study With Good and Poor Sleepers.

    Science.gov (United States)

    Ramlee, Fatanah; Sanborn, Adam N; Tang, Nicole K Y

    2017-07-01

    We conceptualized sleep quality judgment as a decision-making process and examined the relative importance of 17 parameters of sleep quality using a choice-based conjoint analysis. One hundred participants (50 good sleepers; 50 poor sleepers) were asked to choose between 2 written scenarios to answer 1 of 2 questions: "Which describes a better (or worse) night of sleep?". Each scenario described a self-reported experience of sleep, stringing together 17 possible determinants of sleep quality that occur at different times of the day (day before, pre-sleep, during sleep, upon waking, day after). Each participant answered 48 questions. Logistic regression models were fit to their choice data. Eleven of the 17 sleep quality parameters had a significant impact on the participants' choices. The top 3 determinants of sleep quality were: Total sleep time, feeling refreshed (upon waking), and mood (day after). Sleep quality judgments were most influenced by factors that occur during sleep, followed by feelings and activities upon waking and the day after. There was a significant interaction between wake after sleep onset and feeling refreshed (upon waking) and between feeling refreshed (upon waking) and question type (better or worse night of sleep). Type of sleeper (good vs poor sleepers) did not significantly influence the judgments. Sleep quality judgments appear to be determined by not only what happened during sleep, but also what happened after the sleep period. Interventions that improve mood and functioning during the day may inadvertently also improve people's self-reported evaluation of sleep quality. © Sleep Research Society 2017. Published by Oxford University Press [on behalf of the Sleep Research Society].

  6. THE CAUSES STUDY OF THE PREMATURE DESTRUCTION OF THE CONCRETE SLEEPERS ON THE ZNAMENKA TRACK OF THE IF10 OF THE ODESSA RAILWAY

    Directory of Open Access Journals (Sweden)

    V. V. Kovalenko

    2015-11-01

    Full Text Available Purpose. The aim of the paper is to study the factors that led to the premature destruction of concrete sleepers. Methodology. The express-method of determining the morphology and chemical composition of structural components in concrete, patented by Dnipropetrovsk National University of Railway Transport was used in the paper. Methodology makes it possible to control the morphology and chemical composition of cement crystals as the weakest link in the structure of composite material – concrete, and to predict, in accordance with the recommendations of the German Scientists, the possibility of structural transformation of cement in the solid state, which determines the durability of the composite material. Findings. The mass destruction of concrete sleepers on railways of Ukraine is becoming more frequent every year. Moreover, if such destruction in 2010 appears after 4-5 years of operation, in 2015 it is only after 2-3 years of installing the sleepers on the main railways. The nature of the destruction of concrete sleepers can be noted as malty factors influence on it. The batches of cement and other raw materials have been investigated before using with the standard methods in accredited laboratories of PAC «Ukrgeolbudm» (Kyiv and received a positive evaluation for use in the production of concrete sleepers. However, a significant error in experimental data by standard methods not allowed revealing the critical properties of materials that adversely effect on the durability of rail base concrete. According to the research it was determined that the causes of mass destruction of sleepers are: 1 the inhomogeneity of the macrostructure of the concrete, as a consequence of the use of crushed rock of fraction 5-25 mm; 2 the impact of aggressive environment on the surface of the concrete sleepers; 3 the presence of a secondary structure of sleepers of large ettringite crystals prone to restructuring and the presence of alkaline silicic acid

  7. The Sleeper Effect in Persuasion: A Meta-Analytic Review

    Science.gov (United States)

    Kumkale, G. Tarcan; Albarracín, Dolores

    2009-01-01

    A meta-analysis of the available judgment and memory data on the sleeper effect in persuasion is presented. According to this effect, when people receive a communication associated with a discounting cue, such as a noncredible source, they are less persuaded immediately after exposure than they are later in time. Findings from this meta-analysis indicate that recipients of discounting cues were more persuaded over time when the message arguments and the cue had a strong initial impact. In addition, the increase in persuasion was stronger when recipients of discounting cues had higher ability or motivation to think about the message and received the discounting cue after the message. These results are discussed in light of classic and contemporary models of attitudes and persuasion. PMID:14717653

  8. Mechanical and Physical Properties of Polyester Polymer Concrete Using Recycled Aggregates from Concrete Sleepers

    OpenAIRE

    Carrión, F.; Montalban Domingo, Maria Laura; Real Herráiz, Julia Irene; Real, T.

    2014-01-01

    Currently, reuse of solid waste from disused infrastructures is an important environmental issue to study. In this research, polymer concrete was developed by mixing orthophthalic unsaturated polyester resin, artificial microfillers (calcium carbonate) and waste aggregates (basalt and limestone) coming from the recycling process of concrete sleepers. The variation of the mechanical and physical properties of the polymer concrete (compressive strenght, flexural strength, modulus of elasticity,...

  9. Prevalence and impacts of poor sleep on quality of life and associated factors of good sleepers in a sample of older Chinese adults

    Directory of Open Access Journals (Sweden)

    Lo Catherine MH

    2012-06-01

    Full Text Available Abstract Background Sleep disturbance is a complex health problem in ageing global populations decreasing quality of life among many older people. Geographic, cultural, and ethnic differences in sleep patterns have been documented within and between Western and Asian populations. The aim of this study was to explore sleep problems among Hong Kong seniors by examining the prevalence of poor sleep quality, the relationship between sleep quality and health-related quality of life, and associated factors of good sleepers in different age groups. Methods This cross-sectional study used convenience sampling and gathered data during face-to-face interviews. Older community-dwelling individuals (n = 301 were recruited in community centres in 2010. The Pittsburgh Sleep Quality Index and Medical Outcomes Study Short Form-36 were used to measure sleep quality and health-related quality of life. The Medical Outcomes Study Short Form-36 domain scores were compared between good and bad sleepers and between long and short sleepers using Hotelling’s T-Square test. SF-36 domain scores were placed into a logistic regression model that controlled for significant demographic variables (gender, educational level, perceived health. Results Most (77.7% participants were poor sleepers. Participants who had global Pittsburgh Sleep Quality Index scores Conclusions This study found a strong negative association between sleep deprivation (poor quality, short duration and health-related quality of life. Associated factors for good sleep quality in later life differ among age groups in relation to universal age-related changes, and should be addressed by social policies and health-care programmes.

  10. A new genus and species of blind sleeper (Teleostei: Eleotridae) from Oaxaca, Mexico: First obligate cave gobiiform in the Western Hemisphere

    Science.gov (United States)

    Walsh, Stephen J.; Chakrabarty, Prosanta

    2016-01-01

    Caecieleotris morrisi, new genus and species of sleeper (family Eleotridae), is described from a submerged freshwater cave in a karst region of the northern portion of the State of Oaxaca, Mexico, Río Papaloapan drainage, Gulf of Mexico basin. The new species represents the first cave-adapted sleeper known from the Western Hemisphere and is one of only 13 stygobitic gobiiforms known worldwide, with all others limited in distribution to the Indo-Pacific region. The new taxon represents a third independent evolution of a hypogean lifestyle in sleepers, the others being two species ofOxyeleotris (O. caeca and O. colasi) from New Guinea and a single species, Bostrychus microphthalmus, from Sulawesi. Caecieleotris morrisi, new species, is distinguished from epigean eleotrids of the Western Atlantic in lacking functional eyes and body pigmentation, as well as having other troglomorphic features. It shares convergent aspects of morphology with cave-dwelling species of Oxyeleotris and B. microphthalmus but differs from those taxa in lacking cephalic pores and head squamation, among other characters. Description of C. morrisi, new species, brings the total number of eleotrid species known from Mexico to 12. Seven of these, including the new species, occur on the Atlantic Slope.

  11. Geochronology of the Sleeper deposit, Humboldt County, Nevada: epithermal gold-silver mineralization following emplacement of a silicic flow-dome complex

    Science.gov (United States)

    Conrad, J.E.; McKee, E.H.; Rytuba, J.J.; Nash, J.T.; Utterback, W.C.

    1993-01-01

    The high-grade gold-silver deposits at the Sleeper mine are low sulfidation, quartz-adularia-type epithermal deposits, formed during the final stages of igneous hydrothermal activity of a small middle Miocene silicic flow-dome complex in north-central Nevada. There were multiple pulses of alteration and mineralization but all occurred within a period of less than 2 m.y. Later supergene alteration formed opal and alunite about 5.4 Ma but produced no Au or Ag mineralization other than some remobilization to produce locally rich pockets of secondary Au and Ag enrichment and is unrelated to the older magmatic hydrothermal system. The Sleeper deposit in the northern part of the Great Basin is genetically related to bimodal volcanism that followed a long period of arc-related andesitic volcanism in the same general region. -from Authors

  12. Respiratory symptoms are more common among short sleepers independent of obesity

    DEFF Research Database (Denmark)

    Björnsdóttir, Erla; Janson, Christer; Lindberg, Eva

    2017-01-01

    , marital status, exercise and smoking. Excluding BMI from the model covariates did not affect the results. Short sleep was related to 11 out of 16 respiratory and nasal symptoms among subjects with BMI ≥30 and 9 out of 16 symptoms among subjects with BMI sleep......INTRODUCTION: Sleep length has been associated with obesity and various adverse health outcomes. The possible association of sleep length and respiratory symptoms has not been previously described. The aim of this study was to investigate the association between sleep length and respiratory...... Health Survey III. The mean±SD age was 54.2±7.1 (age range 39-67 years). Information was collected on general and respiratory health and sleep characteristics. RESULTS: The mean reported nighttime sleep duration was 6.9±1.0 hours. Short sleepers (

  13. Long-Haul Truck Sleeper Heating Load Reduction Package for Rest Period Idling

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, Jason Aaron; Kekelia, Bidzina; Tomerlin, Jeff; Kreutzer, Cory J.; Yeakel, Skip; Adelman, Steven; Luo, Zhiming; Zehme, John

    2016-04-05

    Annual fuel use for sleeper cab truck rest period idling is estimated at 667 million gallons in the United States, or 6.8% of long-haul truck fuel use. Truck idling during a rest period represents zero freight efficiency and is largely done to supply accessory power for climate conditioning of the cab. The National Renewable Energy Laboratory's CoolCab project aims to reduce heating, ventilating, and air conditioning (HVAC) loads and resulting fuel use from rest period idling by working closely with industry to design efficient long-haul truck thermal management systems while maintaining occupant comfort. Enhancing the thermal performance of cab/sleepers will enable smaller, lighter, and more cost-effective idle reduction solutions. In addition, if the fuel savings provide a one- to three-year payback period, fleet owners will be economically motivated to incorporate them. For candidate idle reduction technologies to be implemented by original equipment manufacturers and fleets, their effectiveness must be quantified. To address this need, several promising candidate technologies were evaluated through experimentation and modeling to determine their effectiveness in reducing rest period HVAC loads. Load reduction strategies were grouped into the focus areas of solar envelope, occupant environment, conductive pathways, and efficient equipment. Technologies in each of these focus areas were investigated in collaboration with industry partners. The most promising of these technologies were then combined with the goal of exceeding a 30% reduction in HVAC loads. These technologies included 'ultra-white' paint, advanced insulation, and advanced curtain design. Previous testing showed more than a 35.7% reduction in air conditioning loads. This paper describes the overall heat transfer coefficient testing of this advanced load reduction technology package that showed more than a 43% reduction in heating load. Adding an additional layer of advanced insulation

  14. Lack of hippocampal volume differences in primary insomnia and good sleeper controls: an MRI volumetric study at 3 Tesla.

    Science.gov (United States)

    Winkelman, John W; Benson, Kathleen L; Buxton, Orfeu M; Lyoo, In Kyoon; Yoon, Sujung; O'Connor, Shawn; Renshaw, Perry F

    2010-06-01

    A recent pilot study reported that hippocampal volume (HV) was reduced in patients with primary insomnia (PI) relative to normal sleepers. Loss of HV in PI might be due to chronic hyperarousal and/or chronic sleep debt. The aim of this study was to replicate the earlier pilot report while employing a larger sample, more rigorous screening criteria, and objective sleep data. This cross-sectional design included community recruits meeting DSM-IV criteria for PI (n=20, 10 males, mean age 39.3+/-8.7) or good sleeper controls (n=15, 9 males, mean age 38.8+/-5.3). All subjects were unmedicated and rigorously screened to exclude comorbid psychiatric and medical illness. PI subjects underwent overnight polysomnography to screen for sleep-related breathing and movement disorders. HV and total brain volumes were derived by MRI employing a Siemens/Trio scanner operating at 3 Tesla. Data also included 2 weeks of sleep diaries and wrist actigraphy. Mean HV was 4322.0+/-299.7 mm(3) for the good sleeper controls and 4601.55+/-537.4 mm(3) for the PI group. The dependent variable, HV, was analyzed by ANCOVA. Main effects were diagnosis and gender; whole brain volume served as the covariate. Although the overall model was significant (F=6.3, p=0.001), the main effects of diagnosis (F=2.14) and gender (F=0.04) were not significant. The covariate of whole brain volume was significant (F=5.74, p=0.023) as was the interaction of diagnosis with gender (F=10.22, p=0.003), with male insomniacs having larger HVs than male controls. This study did not replicate a previously published report of HV loss in primary insomnia. Differences between our finding and the previous report might be due to sample composition and method of MRI assessment. Furthermore, we demonstrated no objective differences between the controls and PIs in actigraphic measures of sleep maintenance. Within the PIs, however, actigraphic measures of poor sleep maintenance were associated with smaller HV. Copyright 2010

  15. Long-Haul Truck Sleeper Heating Load Reduction Package for Rest Period Idling: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, Jason; Kekelia, Bidzina; Tomerlin, Jeff; Kreutzer, Cory; Adelman, Steve; Yeakel, Skip; Luo, Zhiming; Zehme, John

    2016-03-24

    Annual fuel use for sleeper cab truck rest period idling is estimated at 667 million gallons in the United States, or 6.8% of long-haul truck fuel use. Truck idling during a rest period represents zero freight efficiency and is largely done to supply accessory power for climate conditioning of the cab. The National Renewable Energy Laboratory's CoolCab project aims to reduce heating, ventilating, and air conditioning (HVAC) loads and resulting fuel use from rest period idling by working closely with industry to design efficient long-haul truck thermal management systems while maintaining occupant comfort. Enhancing the thermal performance of cab/sleepers will enable smaller, lighter, and more cost-effective idle reduction solutions. In addition, if the fuel savings provide a one- to three-year payback period, fleet owners will be economically motivated to incorporate them. For candidate idle reduction technologies to be implemented by original equipment manufacturers and fleets, their effectiveness must be quantified. To address this need, several promising candidate technologies were evaluated through experimentation and modeling to determine their effectiveness in reducing rest period HVAC loads. Load reduction strategies were grouped into the focus areas of solar envelope, occupant environment, conductive pathways, and efficient equipment. Technologies in each of these focus areas were investigated in collaboration with industry partners. The most promising of these technologies were then combined with the goal of exceeding a 30% reduction in HVAC loads. These technologies included 'ultra-white' paint, advanced insulation, and advanced curtain design. Previous testing showed more than a 35.7% reduction in air conditioning loads. This paper describes the overall heat transfer coefficient testing of this advanced load reduction technology package that showed more than a 43% reduction in heating load. Adding an additional layer of advanced insulation

  16. Mechanical and Physical Properties of Polyester Polymer Concrete Using Recycled Aggregates from Concrete Sleepers

    Directory of Open Access Journals (Sweden)

    Francisco Carrión

    2014-01-01

    Full Text Available Currently, reuse of solid waste from disused infrastructures is an important environmental issue to study. In this research, polymer concrete was developed by mixing orthophthalic unsaturated polyester resin, artificial microfillers (calcium carbonate, and waste aggregates (basalt and limestone coming from the recycling process of concrete sleepers. The variation of the mechanical and physical properties of the polymer concrete (compressive strength, flexural strength, modulus of elasticity, density, and water absorption was analyzed based on the modification of different variables: nature of the recycled aggregates, resin contents (11 wt%, 12 wt%, and 13 wt%, and particle-size distributions of microfillers used. The results show the influence of these variables on mechanical performance of polymer concrete. Compressive and flexural strength of recycled polymer concrete were improved by increasing amount of polyester resin and by optimizing the particle-size distribution of the microfillers. Besides, the results show the feasibility of developing a polymer concrete with excellent mechanical behavior.

  17. Mechanical and physical properties of polyester polymer concrete using recycled aggregates from concrete sleepers.

    Science.gov (United States)

    Carrión, Francisco; Montalbán, Laura; Real, Julia I; Real, Teresa

    2014-01-01

    Currently, reuse of solid waste from disused infrastructures is an important environmental issue to study. In this research, polymer concrete was developed by mixing orthophthalic unsaturated polyester resin, artificial microfillers (calcium carbonate), and waste aggregates (basalt and limestone) coming from the recycling process of concrete sleepers. The variation of the mechanical and physical properties of the polymer concrete (compressive strength, flexural strength, modulus of elasticity, density, and water absorption) was analyzed based on the modification of different variables: nature of the recycled aggregates, resin contents (11 wt%, 12 wt%, and 13 wt%), and particle-size distributions of microfillers used. The results show the influence of these variables on mechanical performance of polymer concrete. Compressive and flexural strength of recycled polymer concrete were improved by increasing amount of polyester resin and by optimizing the particle-size distribution of the microfillers. Besides, the results show the feasibility of developing a polymer concrete with excellent mechanical behavior.

  18. Sleep-Wake Differences in Relative Regional Cerebral Metabolic Rate for Glucose among Patients with Insomnia Compared with Good Sleepers

    Science.gov (United States)

    Kay, Daniel B.; Karim, Helmet T.; Soehner, Adriane M.; Hasler, Brant P.; Wilckens, Kristine A.; James, Jeffrey A.; Aizenstein, Howard J.; Price, Julie C.; Rosario, Bedda L.; Kupfer, David J.; Germain, Anne; Hall, Martica H.; Franzen, Peter L.; Nofzinger, Eric A.; Buysse, Daniel J.

    2016-01-01

    Study Objectives: The neurobiological mechanisms of insomnia may involve altered patterns of activation across sleep-wake states in brain regions associated with cognition, self-referential processes, affect, and sleep-wake promotion. The objective of this study was to compare relative regional cerebral metabolic rate for glucose (rCMRglc) in these brain regions across wake and nonrapid eye movement (NREM) sleep states in patients with primary insomnia (PI) and good sleeper controls (GS). Methods: Participants included 44 PI and 40 GS matched for age (mean = 37 y old, range 21–60), sex, and race. We conducted [18F]fluoro-2-deoxy-d-glucose positron emission tomography scans in PI and GS during both morning wakefulness and NREM sleep at night. Repeated measures analysis of variance was used to test for group (PI vs. GS) by state (wake vs. NREM sleep) interactions in relative rCMRglc. Results: Significant group-by-state interactions in relative rCMRglc were found in the precuneus/posterior cingulate cortex, left middle frontal gyrus, left inferior/superior parietal lobules, left lingual/fusiform/occipital gyri, and right lingual gyrus. All clusters were significant at Pcorrected sleep and wakefulness. Significant group-by-state interactions in relative rCMRglc suggest that insomnia is associated with impaired disengagement of brain regions involved in cognition (left frontoparietal), self-referential processes (precuneus/posterior cingulate), and affect (left middle frontal, fusiform/lingual gyri) during NREM sleep, or alternatively, to impaired engagement of these regions during wakefulness. Citation: Kay DB, Karim HT, Soehner AM, Hasler BP, Wilckens KA, James JA, Aizenstein HJ, Price JC, Rosario BL, Kupfer DJ, Germain A, Hall MH, Franzen PL, Nofzinger EA, Buysse DJ. Sleep-wake differences in relative regional cerebral metabolic rate for glucose among patients with insomnia compared with good sleepers. SLEEP 2016;39(10):1779–1794. PMID:27568812

  19. Racial Profiling and Moral Panic: Operation Thread and the Al-Qaeda Sleeper Cell that Never Was

    Directory of Open Access Journals (Sweden)

    Felix Odartey-Wellington

    2009-01-01

    Full Text Available In August 2003, Canadian and international media broke news of Operation Thread, executed by the Canadian state security apparatus to apprehend 23 South-Asian Muslim members of a “possible Al-Qaeda sleeper cell” in the Greater Toronto Area. After exposing the suspects to domestic and international opprobrium, the state security apparatus conceded that the allegations of terrorism were unfounded. Using material from the National Post and The Globe and Mail, this paper interrogates the mass mediation of Operation Thread as a case of racial profiling situated in a moral panic over “Islamic terrorism” that was created by a section of the Canadian news media and the state security apparatus. Particularly, it shows that the media contested the discourse of the state security apparatus, thus reflecting the contested nature of news as a social power resource. However, there is still a need for the media to be more critical when dealing with cases such as Operation Thread that are informed by racial profiling post September 11.

  20. Experimental Study on the Vibration Control Effect of Long Elastic Sleeper Track in Subways

    Directory of Open Access Journals (Sweden)

    Xiaopei Cai

    2018-01-01

    Full Text Available The vibration effect of urban rail transit has gained attention from both academia and the industry sector. Long Elastic Sleeper Track (LEST is a new structure for vibration reduction which has recently been designed and applied to Chinese subways. However, little research has been devoted to its vibration reduction effect. In this study, field tests were conducted during peak transit hours on Beijing Subway Line 15 to examine the vibration reduction effects of the common ballastless track and LEST on both straight and curved sections. The results demonstrate that although LEST increases the wheel-rail vertical forces, rail vertical displacements, and rail accelerations to some extent, these effects do not threaten subway operational safety, and vibrations of track bed and tunnel wall are positively mitigated. LEST has an obvious vibration reduction effect at frequencies above 40 Hz. In straight track, the vibration of bottom of the tunnel wall measured in one-third octave bands is reduced by 10.52 dB, while the vibration at point on the tunnel wall at 1.5 m height is reduced by 9.60 dB. For the curved track, the vibrations at those two points are reduced by 9.35 dB and 8.44 dB, respectively. This indicates that LEST reduces vibrations slightly more for the straight track than for the curved track.

  1. Pain assessment by children and adolescents during intraosseous anaesthesia using a computerized system (QuickSleeper).

    Science.gov (United States)

    Sixou, Jean-Louis; Marie-Cousin, Alexia; Huet, Adeline; Hingant, Bernard; Robert, Jean-Claude

    2009-09-01

    Intraosseous (IO) anaesthesia has been shown to be effective in children. However, the pain associated with anaesthetic injections, and its acceptance by children, have never been studied. The aim of this study was to assess the pain associated with the IO injection of 4% articaine with 1 : 200 000 epinephrine using the computerized QuickSleeper' system in a population of children and adolescents. IO anaesthesia was performed on patients aged 10.4 +/- 2.6 years of age. The patients assessed their pain on a faces pain scale (FPS) and on a visual analogue scale (VAS). The operators were also asked to assess signs of patient pain/discomfort. No pain or mild discomfort was reported by, respectively, 81.8% (FPS) and 83.9% (VAS) of the patients. Some 58.9% of children with previous experience of dental anaesthesia reported that computerized IO anaesthesia was more comfortable than traditional infiltration methods. Operators noted signs of discomfort during penetration and injection in 18.3% and 25.3% of the patients, respectively. This study showed that the majority of children reported no pain or mild pain when anaesthetic was administered by computerized needle rotation and solution deposition. This technique holds promise for use by trained paediatric dentists.

  2. REM dream activity of insomnia sufferers: a systematic comparison with good sleepers.

    Science.gov (United States)

    Pérusse, Alexandra D; De Koninck, Joseph; Pedneault-Drolet, Maude; Ellis, Jason G; Bastien, Célyne H

    2016-04-01

    The dream activity of patients with primary insomnia (PI) has rarely been studied, especially using in-laboratory dream collection, although dreams could be linked to their state of hyperarousal and their negative waking experiences. The objective of the study was to compare patients with PI and good sleeper controls (GSCs) in terms of dream recall frequency and dream content. Polysomnography was recorded in 12 patients with PI and 12 GSCs (aged between 30 and 45 years) for five consecutive nights. Rapid eye movement (REM) sleep awakenings were enforced on nights 3 and 5 for dream collections. The REM dream collections revealed that the groups were similar in terms of dream recall frequency (p ≤ 0.7). With respect to dream content variables, the dreams of GSCs tended to comprise more positive emotions (p = 0.06), whereas the dreams of patients with PI were characterized by more negative elements than positive ones (p = 0.001). Subjectively, GSCs characterized their dreams as being more pleasant and containing more joy, happiness, and vividness (p ≤ 0.03) than patients with PI. Finally, elevated negative dream content was associated with lower sleep efficiencies in insomnia (p = 0.004). These results suggest that less positive emotions and greater negative content characterize the dreams of patients with PI, which is in line with their waking experiences. One potential explanation could be hyperarousal exacerbating presleep negative mentation, thus contributing to poorer sleep quality. The lack of difference in dream recall frequency is most likely due to the forced awakening "dream collection" procedure. The study of dream activity seems a promising avenue for understanding the 24-h experience of insomnia better and exploring the potential benefits of dream management techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Sleeper Cab Climate Control Load Reduction for Long-Haul Truck Rest Period Idling

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, J. A.; Kreutzer, C.; Adelman, S.; Yeakel, S.; Zehme, J.

    2015-04-29

    Annual fuel use for long-haul truck rest period idling is estimated at 667 million gallons in the United States. The U.S. Department of Energy’s National Renewable Energy Laboratory’s CoolCab project aims to reduce heating, ventilating, and air conditioning (HVAC) loads and resulting fuel use from rest period idling by working closely with industry to design efficient long-haul truck climate control systems while maintaining occupant comfort. Enhancing the thermal performance of cab/sleepers will enable smaller, lighter, and more cost-effective idle reduction solutions. In order for candidate idle reduction technologies to be implemented at the original equipment manufacturer and fleet level, their effectiveness must be quantified. To address this need, a number of promising candidate technologies were evaluated through experimentation and modeling to determine their effectiveness in reducing rest period HVAC loads. For this study, load reduction strategies were grouped into the focus areas of solar envelope, occupant environment, and conductive pathways. The technologies selected for a complete-cab package of technologies were “ultra-white” paint, advanced insulation, and advanced curtains. To measure the impact of these technologies, a nationally-averaged solar-weighted reflectivity long-haul truck paint color was determined and applied to the baseline test vehicle. Using the complete-cab package of technologies, electrical energy consumption for long-haul truck daytime rest period air conditioning was reduced by at least 35% for summer weather conditions in Colorado. The National Renewable Energy Laboratory's CoolCalc model was then used to extrapolate the performance of the thermal load reduction technologies nationally for 161 major U.S. cities using typical weather conditions for each location over an entire year.

  4. Water's Way at Sleepers River watershed – revisiting flow generation in a post-glacial landscape, Vermont USA

    Science.gov (United States)

    Shanley, James B.; Sebestyen, Stephen D.; McDonnell, Jeffrey J.; McGlynn, Brian L.; Dunne, Thomas

    2015-01-01

    The Sleepers River Research Watershed (SRRW) in Vermont, USA, has been the site of active hydrologic research since 1959 and was the setting where Dunne and Black demonstrated the importance and controls of saturation-excess overland flow (SOF) on streamflow generation. Here, we review the early studies from the SRRW and show how they guided our conceptual approach to hydrologic research at the SRRW during the most recent 25 years. In so doing, we chronicle a shift in the field from early studies that relied exclusively on hydrometric measurements to today's studies that include chemical and isotopic approaches to further elucidate streamflow generation mechanisms. Highlights of this evolution in hydrologic understanding include the following: (i) confirmation of the importance of SOF to streamflow generation, and at larger scales than first imagined; (ii) stored catchment water dominates stream response, except under unusual conditions such as deep frozen ground; (iii) hydrometric, chemical and isotopic approaches to hydrograph separation yield consistent and complementary results; (iv) nitrate and sulfate isotopic compositions specific to atmospheric inputs constrain new water contributions to streamflow; and (v) convergent areas, or ‘hillslope hollows’, contribute disproportionately to event hydrographs. We conclude by summarizing some remaining challenges that lead us to a vision for the future of research at the SRRW to address fundamental questions in the catchment sciences.

  5. Application of Sleeper Cab Thermal Management Technologies to Reduce Idle Climate Control Loads in Long-Haul Trucks

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, J. A.; Venson, T.; Adelman, S.; Dehart, C.; Yeakel, S.; Castillo, M. S.

    2012-10-01

    Each intercity long-haul truck in the U.S. idles approximately 1,800 hrs per year, primarily for sleeper cab hotel loads. Including workday idling, over 2 billion gallons of fuel are used annually for truck idling. NREL's CoolCab project works closely with industry to design efficient thermal management systems for long-haul trucks that keep the cab comfortable with minimized engine idling and fuel use. The impact of thermal load reduction technologies on idle reduction systems were characterized by conducting thermal soak tests, overall heat transfer tests, and 10-hour rest period A/C tests. Technologies evaluated include advanced insulation packages, a solar reflective film applied to the vehicle's opaque exterior surfaces, a truck featuring both film and insulation, and a battery-powered A/C system. Opportunities were identified to reduce heating and cooling loads for long-haul truck idling by 36% and 34%, respectively, which yielded a 23% reduction in battery pack capacity of the idle-reduction system. Data were also collected for development and validation of a CoolCalc HVAC truck cab model. CoolCalc is an easy-to-use, simplified, physics-based HVAC load estimation tool that requires no meshing, has flexible geometry, excludes unnecessary detail, and is less time-intensive than more detailed computer-aided engineering modeling approaches.

  6. The association between prolonged sleep onset latency and heart rate dynamics among young sleep-onset insomniacs and good sleepers.

    Science.gov (United States)

    Tsai, Hsin-Jung; Kuo, Terry B J; Lin, Yu-Cheng; Yang, Cheryl C H

    2015-12-30

    A blunting of heart rate (HR) reduction during sleep has been reported to be associated with increased all-cause mortality. An increased incident of cardiovascular events has been observed in patients with insomnia but the relationship between nighttime HR and insomnia remains unclear. Here we investigated the HR patterns during the sleep onset period and its association with the length of sleep onset latency (SOL). Nineteen sleep-onset insomniacs (SOI) and 14 good sleepers had their sleep analyzed. Linear regression and nonlinear Hilbert-Huang transform (HHT) of the HR slope were performed in order to analyze HR dynamics during the sleep onset period. A significant depression in HR fluctuation was identified among the SOI group during the sleep onset period when linear regression and HHT analysis were applied. The magnitude of the HR reduction was associated with both polysomnography-defined and subjective SOL; moreover, we found that the linear regression and HHT slopes of the HR showed great sensitivity with respect to sleep quality. Our findings indicate that HR dynamics during the sleep onset period are sensitive to sleep initiation difficulty and respond to the SOL, which indicates that the presence of autonomic dysfunction would seem to affect the progress of falling asleep. Copyright © 2015. Published by Elsevier Ireland Ltd.

  7. Cross-well slug testing in unconfined aquifers: A case study from the Sleepers River Watershed, Vermont

    Science.gov (United States)

    Belitz, K.; Dripps, W.

    1999-01-01

    Normally, slug test measurements are limited to the well in which the water level is perturbed. Consequently, it is often difficult to obtain reliable estimates of hydraulic properties, particularly if the aquifer is anisotropic or if there is a wellbore skin. In this investigation, we use partially penetrating stress and observation wells to evaluate specific storage, radial hydraulic conductivity and anisotropy of the aquifer, and the hydraulic conductivity of the borehole skin. The study site is located in the W9 subbasin of the Sleepers River Research Watershed, Vermont. At the site, ~3 m of saturated till are partially penetrated by a stress well located in the center of the unconfined aquifer and six observation wells located above, below, and at the depth of the stress well at radial distances of 1.2 and 2.4 m. The observation wells were shut in with inflatable packers. The semianalytical solution of Butler (1995) was used to conduct a sensitivity analysis and to interpret slug test results. The sensitivity analysis indicates that the response of the stress well is primarily sensitive to radial hydraulic conductivity, less sensitive to anisotropy and the conductivity of the borehole skin, and nearly insensitive to specific storage. In contrast, the responses of the observation wells are sensitive to all four parameters. Interpretation of the field data was facilitated by generating type curves in a manner analogous to the method of Cooper et al. (1967). Because the value of radial hydraulic conductivity is obtained from a match point, the number of unknowns is reduced to three. The estimated values of radial hydraulic conductivity and specific storage are comparable to those derived from the methods of Bouwer and Rice (1976) and Cooper et al. (1967). The values and skin conductivity, however, could not have been obtained without the use of observation wells.Normally, slug test measurements are limited to the well in which the water level is perturbed

  8. Subjective-Objective Sleep Discrepancy Is Associated With Alterations in Regional Glucose Metabolism in Patients With Insomnia and Good Sleeper Controls.

    Science.gov (United States)

    Kay, Daniel B; Karim, Helmet T; Soehner, Adriane M; Hasler, Brant P; James, Jeffrey A; Germain, Anne; Hall, Martica H; Franzen, Peter L; Price, Julie C; Nofzinger, Eric A; Buysse, Daniel J

    2017-11-01

    Sleep discrepancies are common in primary insomnia (PI) and include reports of longer sleep onset latency (SOL) than measured by polysomnography (PSG) or "negative SOL discrepancy." We hypothesized that negative SOL discrepancy in PI would be associated with higher relative glucose metabolism during nonrapid eye movement (NREM) sleep in brain networks involved in conscious awareness, including the salience, left executive control, and default mode networks. PI (n = 32) and good sleeper controls (GS; n = 30) completed [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) scans during NREM sleep, and relative regional cerebral metabolic rate for glucose (rCMRglc) was measured. Sleep discrepancy was calculated by subtracting PSG-measured SOL on the PET night from corresponding self-report values the following morning. We tested for interactions between group (PI vs. GS) and SOL discrepancy for rCMRglc during NREM sleep using both a region of interest mask and exploratory whole-brain analyses. Significant group by SOL discrepancy interactions for rCMRglc were observed in several brain regions (pcorrected PSG-measured SOL) was associated with significantly higher relative rCMRglc in the right anterior insula and middle/posterior cingulate during NREM sleep. In GS, more positive SOL discrepancy (self-reported Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  9. Sustained and "sleeper" effects of group metacognitive training for schizophrenia: a randomized clinical trial.

    Science.gov (United States)

    Moritz, Steffen; Veckenstedt, Ruth; Andreou, Christina; Bohn, Francesca; Hottenrott, Birgit; Leighton, Lucy; Köther, Ulf; Woodward, Todd S; Treszl, András; Menon, Mahesh; Schneider, Brooke C; Pfueller, Ute; Roesch-Ely, Daniela

    2014-10-01

    completion rate was 61.3% after 3 years. Metacognitive training demonstrated sustained effects in the reduction of delusions, which were over and above the effects of antipsychotic medication. Moreover, there were some unanticipated ("sleeper") effects as both self-esteem and quality of life were improved after 3 years. Effects on self-esteem and well-being were found even in the absence of an improvement on the jumping to conclusions bias. isrctn.org Identifier: ISRCTN95205723.

  10. The developmental feature of the sleep problems in adolescence : The approach for the application to educational stage

    OpenAIRE

    Tanaka, Hideki; Hayashi, Mitsuo; Hori, Tadao

    1997-01-01

    To clarify the actual feature of the sleep problems in adolescence from the points of view sleep loss, circadian rhythm, and development, the survey for five years was performed on 523 students in a College of Technology. The survey results were analyzed in regard to the Sleep Habits Scales and the Life Habits Scales. These scales were (1) Long sleeper-Short sleeper, (2) Good sleeper-Poor sleeper, (3) Sleep phase advanced type-Sleep phase delayed type, (4) Morningness-Eveningness, (5) Regnlar...

  11. Bazalt Agregası ile Üretilen Beton Travers de Çelik Lifin Kullanılabilirliğinin Araştırılması

    Directory of Open Access Journals (Sweden)

    Mehmet KOZAK

    2015-01-01

    Full Text Available In this study, the aggregates produced by the basalt fiber concrete sleeper steel was researched. In the study, the maximum aggregate particle size and varying the amount by volume of steel fibers for a total of 6 different series are manufactured separately. Separately from each series including 2 and 4 cubes produced concrete sleepers are subjected to steam curing. Produced on the flexural strength of concrete sleepers and ultrasonic velocity cube on samples 1 and the 28day compressive strength, unit weight, ultrasonic pulse velocity, freeze-thaw and water absorption tests were carried out. According to the results obtained, in the production of steel fiber concrete sleepers use increases the mechanical properties, particularly flexural strength was observed. This study also produced all of the series, TCDD Afyon Concrete Sleeper Plant by the single block B.58 concrete sleepers production as the threshold value that is being used, Dywidag in terms of norms, 28day compressive strength and flexural strength can be said to provide

  12. Sleep Hygiene and Sleep Quality of Third-Trimester Pregnant Women.

    Science.gov (United States)

    Tsai, Shao-Yu; Lee, Chien-Nan; Wu, Wei-Wen; Landis, Carol A

    2016-02-01

    The purpose of this descriptive study was to examine the associations of sleep hygiene and actigraphy measures of sleep with self-reported sleep quality in 197 pregnant women in northern Taiwan. Third-trimester pregnant women completed the Sleep Hygiene Practice Scale (SHPS) and the Pittsburgh Sleep Quality Index (PSQI) as well as the Center for Epidemiologic Studies-Depression Scale (CES-D), and wore an actigraph for 7 consecutive days. Student's t-test was used to compare the SHPS scores and means as well as variability of actigraphy sleep variables between poor sleepers (i.e., PSQI global score >5) and good sleepers (i.e., PSQI global score ≤5). Compared to good sleepers, poor sleepers reported significantly worse sleep hygiene, with higher SHPS scores and higher sleep schedule, arousal-related behavior, and sleep environment subscale scores. Poor sleepers had significantly greater intra-individual variability of sleep onset latency, total nighttime sleep, and wake after sleep onset than good sleepers. In stepwise linear regression, older maternal age (p = .01), fewer employment hours per week (p = .01), higher CES-D total score (p hygiene intervention in women during pregnancy. © 2015 Wiley Periodicals, Inc.

  13. An examination of sleep health, lifestyle and mental health in junior high school students.

    Science.gov (United States)

    Tanaka, Hideki; Taira, Kazuhiko; Arakawa, Masashi; Masuda, Atushi; Yamamoto, Yukari; Komoda, Yoko; Kadegaru, Hathuko; Shirakawa, Shuichiro

    2002-06-01

    The factors that influence sleep health and mental health in junior high school students' lifestyles was examined. The proportion of students who replied that they feel bad in the morning, and who do not have breakfast was significantly higher in poor sleepers. The proportion of students who regularly take exercise was significantly lower among poor sleepers. Compared with good sleepers, poor sleepers had a higher number of illnesses and their General Health Questionnaire score was worse. The study's results suggest that sleep health is closely related to both physical and mental health, and that habits such as exercise, and regular sleeping and eating, are important for maintaining and improving students' sleep health.

  14. Influence of environmental pollution with creosote oil or its vapors on biomass and selected physiological groups of microorganisms

    Science.gov (United States)

    Krzyśko-Łupicka, Teresa; Cybulska, Krystyna; Kołosowski, Paweł; Telesiński, Arkadiusz; Sudoł, Adam

    2017-11-01

    Survival of microorganisms in soils from treatment facility and landfill of wooden railway sleepers contaminated with creosote oil as well as in two types of soils with different content of organic carbon, treated with creosote oil vapors, was assessed. Microbiological assays including determination of: the biomass of living microorganisms method and the number of proteolytic, lipolytic and amylolytic microorganisms were carried out under laboratory conditions. Chromatography analysis of the soil extract from railway sleepers treatment facility was performed using GC/MS. The highest biomass and the number of tested microorganisms were determined in soils from wooden railway sleepers landfill, while the lowest in soil from the railway sleepers treatment facility. Vapors of creosote oil, regardless of the soil type, significantly increased only the number of lipolytic bacteria.

  15. Seasonal patterns in metazoan parasite community of the "Fat Sleeper" Dormitator latifrons (Pisces: Eleotridae from Tres Palos Lagoon, Guerrero, Mexico

    Directory of Open Access Journals (Sweden)

    Juan Violante-González

    2008-09-01

    Full Text Available Dormitator is among the most important fish genera in the Mexican Pacific coastal lagoon systems. In Tres Palos Lagoon, the Fat Sleeper Dormitator latifrons is one of the most significant species based on catch volume, although it is only consumed locally. Very little information exists on this species’ parasitofauna. Composition and temporal variation in the metazoan parasite community structure of Dormitator latifrons from Tres Palos Lagoon (99º47’ W, 16º48’ N, Guerrero, Mexico, were determined using seasonal samples taken between April 2000 and June 2002. Ten parasite species (55 817 individuals were recovered from 219 examined hosts. These species included eight helminths (Ascocotyle (Phagicola longa, Echinochasmus leopoldinae, Clinostomum complanatum, Pseudoacanthostomum panamense, Saccocoelioides lamothei, Parvitaenia cochlearii, Contracaecum sp. and Neoechinorhynchus golvani and two crustaceans (Argulus sp. and Ergasilus sp.. Five of the helminth species exhibited seasonal variation in their infection dynamics associated with environmental changes during the dry and rainy seasons. The variations in the infection dynamics generated changes in the community structure over time. Rev. Biol. Trop. 56 (3: 1419-1427. Epub 2008 September 30.Entre abril del 2000 y junio del 2002 se efectuó un estudio para determinar la composición y la variación temporal en la estructura de la comunidad de parásitos metazoarios del popoyote Dormitator latifrons en la laguna de Tres Palos, Guerrero, México, a partir de muestras temporales. Se recuperaron diez especies de parásitos (55 817 individuos de 219 hospederos examinados. Estas especies incluyeron ocho helmintos (Ascocotyle (Phagicola longa, Echinochasmus leopoldinae, Clinostomum complanatum, Pseudoacanthostomum panamense, Saccocoelioides lamothei, Parvitaenia cochlearii, Contracaecum sp. y Neoechinorhynchus golvani y dos crustáceos (Argulus sp. y Ergasilus sp.. Cinco de las especies de

  16. The stuff that dreams aren't made of: why wake-state and dream-state sensory experiences differ.

    Science.gov (United States)

    Symons, D

    1993-06-01

    It is adaptive for individuals to be continuously alert and responsive to external stimuli (such as the sound and odor of an approaching predator or the cry of an infant), even during sleep. Natural selection thus has disfavored the occurrence during sleep of hallucinations that compromise external vigilance. In the great majority of mammalian species, including Homo sapiens, closed eyes and immobility are basic aspects of sleep. Therefore, (a) visual and movement sensory modalities (except kinesthesis) do not provide the sleeper with accurate information about the external environment or the sleeper's relationship to that environment; (b) the sleeper's forebrain "vigilance mechanism" does not monitor these modalities; hence (c) visual and movement hallucinations--similar or identical to percepts--can occur during sleep without compromising vigilance. In contrast, the other sensory modalities do provide the sleeper with a continuous flow of information about the external environment or the sleeper's relationship to that environment, and these modalities are monitored by the vigilance mechanism. Hallucinations of kinesthesis, pain, touch, warmth, cold, odor, and sound thus would compromise vigilance, and their occurrence during sleep has been disfavored by natural selection. This vigilance hypothesis generates novel predictions about dream phenomenology and REM-state neurophysiology and has implications for the general study of imagery.

  17. Sleep Quality Among Low-Income Young Women in Southeast Texas Predicts Changes in Perceived Stress Through Hurricane Ike.

    Science.gov (United States)

    Wu, Zhao Helen; Stevens, Richard G; Tennen, Howard; North, Carol S; Grady, James J; Holzer, Charles

    2015-07-01

    To document the time course of perceived stress among women through the period of a natural disaster, to determine the effect of sleep quality on this time course, and to identify risk factors that predict higher levels of perceived stress. Longitudinal study from 2006-2012. Community-based family planning clinics in southeast Texas. There were 296 women aged 18-31 y who experienced Hurricane Ike, September 2008. Cohen Perceived Stress Scale (PSS) was administered every 2 mo from 6 mo before to 12 mo after Hurricane Ike. Sleep quality was assessed 1 mo after Hurricane Ike using the Pittsburg Sleep Quality Index (PSQI). Good sleep was defined as a PSQI summary score sleep as a score ≥ 5. Hurricane Ike stressors (e.g., property damage, subjective stressors) and pre-Ike lifetime major life events and emotional health (e.g., emotional dysregulation, self-control) were also assessed. Over the entire period of 18 mo (6 mo before and 12 mo after the hurricane), perceived stress was significantly higher among poor sleepers compared to good sleepers, and only good sleepers showed a significant decrease in perceived stress after Hurricane Ike. In addition, a higher level of perceived stress was positively associated with greater Ike damage among poor sleepers, whereas this correlation was not observed among good sleepers. In the final multivariate longitudinal model, Ike-related subjective stressors as well as baseline major life events and emotional dysregulation among poor sleepers predicted higher levels of perceived stress over time; among good sleepers, additional factors such as lower levels of self-control and having a history of a psychiatric disorder also predicted higher levels of perceived stress. Sleep quality after Hurricane Ike, an intense natural disaster producing substantial damage, impacted changes in perceived stress over time. Our findings suggest the possibility that providing victims of disasters with effective interventions to improve sleep quality

  18. Professional correlates of insomnia.

    Science.gov (United States)

    Léger, Damien; Massuel, Marie-Anne; Metlaine, Arnaud

    2006-02-01

    Insomnia is a highly prevalent disorder that affects daytime functioning, behavior, and quality of life. Several reports have shown that insomnia impacts on the workforce and is associated with an increased risk of absenteeism. However, few workplace studies have been performed. Our study attempted to evaluate the professional correlates of insomnia by comparing a group of workers with insomnia to a matched group of good sleepers. The main objective measure was absenteeism. Accidents, self-esteem at work, job satisfaction, and efficiency at work were also investigated. Pairs of workers with insomnia (according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition definition) and good sleepers, matched by age, sex, and occupational status, were interviewed by their occupational physician and also answered a self-administered questionnaire on work-related criteria. Objective data on absenteeism (number of days absent from work) were provided by the employers' health resource databases. Paris and the Ile de France region (France). Seven hundred eighty-five subjects completed the questionnaire. We retained 369 pair (ie, 738 subjects) for analysis. Insomniacs missed work twice as often as good sleepers. The difference between insomniacs and good sleepers in terms of absenteeism was particularly high for blue-collar workers (odds ratio = 3.0) and men (odds ratio = 2.31). Insomniacs had also a higher accident rate while driving and, strikingly, a 3-fold greater risk of having 2 or 3 serious road accidents. They also reported poor self-esteem at work, less job satisfaction, and less efficiency at work, compared with good sleepers. Our study found an objective increase in absenteeism in insomniacs compared with good sleepers.

  19. EXPERIMENTAL INVESTIGATIONS OF INTERACTION OF TRACK AND ROLLING STOCK ON CROSSOVERS

    Directory of Open Access Journals (Sweden)

    M. A. Arbuzov

    2016-10-01

    Full Text Available Purpose. Recently on the Ukrainian railways network more attention is paid to the cases of violations in the maintenance of crossovers, which may lead to deterioration of the train traffic safety conditions. As a rule, such violations occur as a result of inaccuracies during crossover pegging and laying, as well as are the consequence of impact of rolling stock and thermal forces. The appearance of geometrical irregularities can also be triggered by violation of the scheme of layout of concrete sleepers in the crossover turnout curve with intertrack spaces of less than 5.3 m. Therefore, we have decided to analyze the impact of the presence of deviations from the layout scheme of the sleepers and geometric irregularities on the conditions of track and rolling stock interaction based on the results of experimental investigations. It was also decided to establish a connection between the stress-strain states of the track and the presence of short sleepers. Methodology. The effect of deviations from the layout scheme of the sleepers and geometric irregularities on the interaction conditions of track and rolling stock was studied by means of theoretical calculations and experimental research. The experimental research covered the area on the non-public railway tracks that meets the required conditions for scientific and research work on the territory of «Transinvestservice» company. Findings. The distribution of stresses and forces acting on a railway track depending on speed movement of experienced rolling stock was obtained. In addition we obtained the data on the influence of the sleeper geometric parameters on its stress-strain state. Originality. For the first time the paper assessed the impact of rolling stock in the presence of geometrical irregularities and asymmetrically truncated sleepers within the crossover connection part on the stress-strain state of track in this zone. In addition, we compared the results for the area with common and

  20. The association between self-reported sleep quality and metabolic syndrome.

    Directory of Open Access Journals (Sweden)

    Hao-Chang Hung

    Full Text Available OBJECTIVES: Short and long sleep duration are associated with metabolic syndrome. However, there is limited research on the association between sleep quality and metabolic syndrome, and thus the aim of this study is to investigate this relationship. MATERIALS AND METHODS: The cross-sectional baseline data were collected from the decoded database of the Prevention Health Center of National Cheng Kung University Hospital from 2002 to 2006. The diagnosis of metabolic syndrome was according to the statement of the American Heart Association/National Heart, Lung, and Blood Institute. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI. A higher global PSQI score indicates poorer sleep quality, and a global PSQI score greater than five differentiates poor from good sleepers. RESULTS: Of the 3,435 subjects recruited, 899 (26.2% had metabolic syndrome. Subjects with metabolic syndrome had higher PSQI and prevalence of poor sleepers than those without metabolic syndrome. The multivariate lineal regression analysis showed that female gender, metabolic syndrome, sleep duration, snoring, alcohol drinking, and habitual exercise were independent predictors of PSQI. When substituting metabolic syndrome with the five components, hyperglycemia and low high-density lipoprotein cholesterol (HDL-C were positively associated with PSQI. The multivariate logistic regression analyses showed that female gender, metabolic syndrome, sleep duration, and snoring were independently associated with being poor sleepers. Of the five components, only low HDL-C was an independent predictor of being poor sleepers. CONCLUSIONS: Subjects with metabolic syndrome have higher global PSQI scores and a higher risk of being poor sleepers. Of the five components of metabolic syndrome, hyperglycemia and low HDL-C are independently associated with the global PSQI scores, while low HDL-C is an independent predictor of being poor sleepers.

  1. Sex-Specific Associations Between Self-reported Sleep Duration, Cardiovascular Disease, Hypertension, and Mortality in an Elderly Population.

    Science.gov (United States)

    Broström, Anders; Wahlin, Ake; Alehagen, Urban; Ulander, Martin; Johansson, Peter

    2017-01-05

    Both short and long sleep durations have been associated to increased mortality. Knowledge about sex-specific differences among elderly regarding associations between sleep duration, cardiovascular health, and mortality is sparse. The aims of this study are to examine the association between self-reported sleep duration and mortality and to investigate whether this association is sex specific and/or moderated by cardiovascular morbidity, and also to explore potential mediators of sleep duration effects on mortality. A population-based, observational, cross-sectional design with 6-year follow-up with mortality as primary outcome was conducted. Self-rated sleep duration, clinical examinations, echocardiography, and blood samples (N-terminal fragment of proBNP) were collected. A total of 675 persons (50% women; mean age, 78 years) were divided into short sleepers (≤6 hours; n = 231), normal sleepers (7-8 hours; n = 338), and long sleepers (≥9 hours; n = 61). Data were subjected to principal component analyses. Cardiovascular disease (CVD) and hypertension factors were extracted and used as moderators and as mediators in the regression analyses. During follow-up, 55 short sleepers (24%), 68 normal sleepers (20%), and 21 long sleepers (34%) died. Mediator analyses showed that long sleep was associated with mortality in men (hazard ratio [HR], 1.8; P = .049), independently of CVD and hypertension. In men with short sleep, CVD acted as a moderator of the association with mortality (HR, 4.1; P = .025). However, when using N-terminal fragment of proBNP, this effect became nonsignificant (HR, 3.1; P = .06). In woman, a trend to moderation involving the hypertension factor and short sleep was found (HR, 4.6; P = .09). Short and long sleep duration may be seen as risk markers, particularly among older men with cardiovascular morbidity.

  2. Seven to Eight Hours of Sleep a Night Is Associated with a Lower Prevalence of the Metabolic Syndrome and Reduced Overall Cardiometabolic Risk in Adults

    Science.gov (United States)

    Chaput, Jean-Philippe; McNeil, Jessica; Després, Jean-Pierre; Bouchard, Claude; Tremblay, Angelo

    2013-01-01

    Background Previous studies looking at the relationship between sleep duration and the metabolic syndrome have only used a dichotomous approach (presence/absence) and failed to adjust for important confounding factors. The objective of the present study was to examine the association between self-reported sleep duration and features of the metabolic syndrome in adults. Methods A cross-sectional analysis from the Quebec Family Study (Canada) was conducted on 810 participants aged 18 to 65 years. Participants were categorized as short (≤6 h), adequate (7–8 h) or long (≥9 h) sleepers. The metabolic syndrome was defined according to the American Heart Association/National Heart, Lung, and Blood Institute’s criteria. Results Overall, 24.6% of the sample had the metabolic syndrome. A U-shaped relationship between sleep duration and the prevalence of metabolic syndrome (33.3%, 22.0% and 28.8% in short, adequate and long sleepers, respectively) was observed (Pmetabolic syndrome (OR = 1.76, 95% CI = 1.08–2.84) compared to adequate sleepers after adjustment for age, sex, smoking habits, highest education level, total annual family income, alcohol consumption, coffee intake, menopausal status, daily caloric intake, and moderate-to-vigorous physical activity. Likewise, the clustered cardiometabolic risk score (i.e. continuous risk score based on the metabolic syndrome components) was significantly higher in short sleepers compared to adequate sleepers after adjustment for covariates (Pmetabolic syndrome after adjusting for possible confounders. These results strongly suggest that short sleep duration is a risk factor for the metabolic syndrome. PMID:24039808

  3. Sleep schedules and school performance in Indigenous Australian children.

    Science.gov (United States)

    Blunden, Sarah; Magee, Chris; Attard, Kelly; Clarkson, Larissa; Caputi, Peter; Skinner, Timothy

    2018-04-01

    Sleep duration and sleep schedule variability have been related to negative health and well-being outcomes in children, but little is known about Australian Indigenous children. Data for children aged 7-9 years came from the Australian Longitudinal Study of Indigenous Children and the National Assessment Program-Literacy and Numeracy (NAPLAN). Latent class analysis determined sleep classes taking into account sleep duration, bedtimes, waketimes, and variability in bedtimes from weekdays to weekends. Regression models tested whether the sleep classes were cross-sectionally associated with grade 3 NAPLAN scores. Latent change score modeling then examined whether the sleep classes predicted changes in NAPLAN performance from grades 3 to 5. Five sleep schedule classes were identified: normative sleep, early risers, long sleep, variable sleep, and short sleep. Overall, long sleepers performed best, with those with reduced sleep (short sleepers and early risers) performing the worse on grammar, numeracy, and writing performance. Latent change score results also showed that long sleepers performed best in spelling and writing and short sleepers and typical sleepers performed the worst over time. In this sample of Australian Indigenous children, short sleep was associated with poorer school performance compared with long sleep, with this performance worsening over time for some performance indicators. Other sleep schedules (eg, early wake times and variable sleep) also had some relationships with school performance. As sleep scheduling is modifiable, this offers opportunity for improvement in sleep and thus performance outcomes for these and potentially all children. Copyright © 2018 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.

  4. Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep.

    Science.gov (United States)

    Harbison, Susan T; Serrano Negron, Yazmin L; Hansen, Nancy F; Lobell, Amanda S

    2017-12-01

    Why do some individuals need more sleep than others? Forward mutagenesis screens in flies using engineered mutations have established a clear genetic component to sleep duration, revealing mutants that convey very long or short sleep. Whether such extreme long or short sleep could exist in natural populations was unknown. We applied artificial selection for high and low night sleep duration to an outbred population of Drosophila melanogaster for 13 generations. At the end of the selection procedure, night sleep duration diverged by 9.97 hours in the long and short sleeper populations, and 24-hour sleep was reduced to 3.3 hours in the short sleepers. Neither long nor short sleeper lifespan differed appreciably from controls, suggesting little physiological consequences to being an extreme long or short sleeper. Whole genome sequence data from seven generations of selection revealed several hundred thousand changes in allele frequencies at polymorphic loci across the genome. Combining the data from long and short sleeper populations across generations in a logistic regression implicated 126 polymorphisms in 80 candidate genes, and we confirmed three of these genes and a larger genomic region with mutant and chromosomal deficiency tests, respectively. Many of these genes could be connected in a single network based on previously known physical and genetic interactions. Candidate genes have known roles in several classic, highly conserved developmental and signaling pathways-EGFR, Wnt, Hippo, and MAPK. The involvement of highly pleiotropic pathway genes suggests that sleep duration in natural populations can be influenced by a wide variety of biological processes, which may be why the purpose of sleep has been so elusive.

  5. Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep.

    Directory of Open Access Journals (Sweden)

    Susan T Harbison

    2017-12-01

    Full Text Available Why do some individuals need more sleep than others? Forward mutagenesis screens in flies using engineered mutations have established a clear genetic component to sleep duration, revealing mutants that convey very long or short sleep. Whether such extreme long or short sleep could exist in natural populations was unknown. We applied artificial selection for high and low night sleep duration to an outbred population of Drosophila melanogaster for 13 generations. At the end of the selection procedure, night sleep duration diverged by 9.97 hours in the long and short sleeper populations, and 24-hour sleep was reduced to 3.3 hours in the short sleepers. Neither long nor short sleeper lifespan differed appreciably from controls, suggesting little physiological consequences to being an extreme long or short sleeper. Whole genome sequence data from seven generations of selection revealed several hundred thousand changes in allele frequencies at polymorphic loci across the genome. Combining the data from long and short sleeper populations across generations in a logistic regression implicated 126 polymorphisms in 80 candidate genes, and we confirmed three of these genes and a larger genomic region with mutant and chromosomal deficiency tests, respectively. Many of these genes could be connected in a single network based on previously known physical and genetic interactions. Candidate genes have known roles in several classic, highly conserved developmental and signaling pathways-EGFR, Wnt, Hippo, and MAPK. The involvement of highly pleiotropic pathway genes suggests that sleep duration in natural populations can be influenced by a wide variety of biological processes, which may be why the purpose of sleep has been so elusive.

  6. Diabetic nephropathy: a strong predictor of sleep quality in hemodialysis patients.

    Science.gov (United States)

    Edalat-Nejad, Mahnaz; Jafarian, Nahid; Yousefichaijan, Parsa

    2014-07-01

    Sleep complaints are common in hemodialysis (HD) patients. Sleep quality (SQ) is a predictor of quality of life and mortality risk in HD. The aim of this study was to examine factors that may have a role in SQ. In this cross-sectional analytic study, 138 end-stage renal disease patients receiving maintenance HD for >3 months were included. The Pittsburgh Sleep Quality Index (PSQI) was used to measure individual's SQ. Patients with a global PSQI score >5 were assumed as poor sleepers. Eighty-eight patients (64%) were classified as poor sleepers. Poor sleepers were older and more likely had diabetes. They had significantly higher serum ferritin and calcium levels and lower serum parathyroid hormone level (all P-values attention to the care of this subgroup with regard to the diagnosis and management of sleep complaints.

  7. Monthly fluctuations of insomnia symptoms in a population-based sample.

    Science.gov (United States)

    Morin, Charles M; Leblanc, M; Ivers, H; Bélanger, L; Mérette, Chantal; Savard, Josée; Jarrin, Denise C

    2014-02-01

    To document the monthly changes in sleep/insomnia status over a 12-month period; to determine the optimal time intervals to reliably capture new incident cases and recurrent episodes of insomnia and the likelihood of its persistence over time. Participants were 100 adults (mean age = 49.9 years; 66% women) randomly selected from a larger population-based sample enrolled in a longitudinal study of the natural history of insomnia. They completed 12 monthly telephone interviews assessing insomnia, use of sleep aids, stressful life events, and physical and mental health problems in the previous month. A total of 1,125 interviews of a potential 1,200 were completed. Based on data collected at each assessment, participants were classified into one of three subgroups: good sleepers, insomnia symptoms, and insomnia syndrome. At baseline, 42 participants were classified as good sleepers, 34 met criteria for insomnia symptoms, and 24 for an insomnia syndrome. There were significant fluctuations of insomnia over time, with 66% of the participants changing sleep status at least once over the 12 monthly assessments (51.5% for good sleepers, 59.5% for insomnia syndrome, and 93.4% for insomnia symptoms). Changes of status were more frequent among individuals with insomnia symptoms at baseline (mean = 3.46, SD = 2.36) than among those initially classified as good sleepers (mean = 2.12, SD = 2.70). Among the subgroup with insomnia symptoms at baseline, 88.3% reported improved sleep (i.e., became good sleepers) at least once over the 12 monthly assessments compared to 27.7% whose sleep worsened (i.e., met criteria for an insomnia syndrome) during the same period. Among individuals classified as good sleepers at baseline, risks of developing insomnia symptoms and syndrome over the subsequent months were, respectively, 48.6% and 14.5%. Monthly assessment over an interval of 6 months was found most reliable to estimate incidence rates, while an interval of 3 months proved the most

  8. Is daily routine important for sleep? An investigation of social rhythms in a clinical insomnia population.

    Science.gov (United States)

    Moss, Taryn G; Carney, Colleen E; Haynes, Patricia; Harris, Andrea L

    2015-02-01

    Social rhythms, also known as daily routines (e.g. exercise, of school or work, recreation, social activities), have been identified as potential time cues to help to regulate the biological clock. Past research has shown links between regularity and healthy sleep. This study examined the regularity and frequency of daytime activities in a clinical insomnia population and a good sleeper comparison group. Participants (N = 69) prospectively monitored their sleep and daily activities for a 2-week period. Although participants with insomnia and good sleepers had similar levels of activity, relative to good sleepers, those with insomnia were less regular in their activities. Findings from this study add to the growing number of studies that highlight the relative importance of the regularity of daytime activities on sleep. Accordingly, future research should test treatment components that focus on regulating daytime activities, which would likely improve treatment outcomes.

  9. Eating behavior by sleep duration in the Hispanic Community Health Study/Study of Latinos.

    Science.gov (United States)

    Mossavar-Rahmani, Yasmin; Jung, Molly; Patel, Sanjay R; Sotres-Alvarez, Daniela; Arens, Raanan; Ramos, Alberto; Redline, Susan; Rock, Cheryl L; Van Horn, Linda

    2015-12-01

    Sleep is an important pillar of health and a modifiable risk factor for diabetes, stroke and obesity. Little is known of diet and sleep patterns of Hispanics/Latinos in the US. Here we examine eating behavior as a function of sleep duration in a sub-sample of 11,888 participants from the Hispanic Community Health Study/Study of Latinos, a community-based cohort study of Hispanics aged 18-74 years in four US cities. Using a cross-sectional probability sample with self-report data on habitual sleep duration and up to two 24-h dietary recalls, we quantified the Alternative Healthy Eating Index (AHEI-2010) score, a measure of diet quality, and intake of selected nutrients related to cardiovascular health. Linear regression models were fit to estimate least-square means of usual nutrient intake of saturated fats, potassium density, fiber, calcium, caffeine and the AHEI-2010 score by sleep duration adjusting for age, sex, Hispanic/Latino background, income, employment status, education, depressive symptomology, and years lived in the US. Distribution of calories over the day and association with sleep duration and BMI were also examined. Short sleepers (≤6 h) had significantly lower intake of potassium, fiber and calcium and long sleepers (≥9 h) had significantly lower intake of caffeine compared to others sleepers after adjusting for covariates. However no difference in the AHEI-2010 score was seen by sleep duration. Significantly more long sleepers, compared to intermediate and short sleepers, reported having ≥30% total daily calories before bedtime. Not consuming a snack or meal within 3 h before bedtime was associated with higher AHEI-2010 scores. These findings identify novel differences in dietary patterns by sleep duration in a Hispanic/Latino cohort in the U.S. CLINICALTRIALS. NCT02060344. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Patients with primary insomnia in the sleep laboratory: do they present with typical nights of sleep?

    Science.gov (United States)

    Hirscher, Verena; Unbehaun, Thomas; Feige, Bernd; Nissen, Christoph; Riemann, Dieter; Spiegelhalder, Kai

    2015-08-01

    The validity of sleep laboratory investigations in patients with insomnia is important for researchers and clinicians. The objective of this study was to examine the first-night effect and the reverse first-night effect in patients with chronic primary insomnia compared with good sleeper controls. A retrospective comparison of a well-characterised sample of 50 patients with primary insomnia and 50 good sleeper controls was conducted with respect to 2 nights of polysomnography, and subjective sleep parameters in the sleep laboratory and the home setting. When comparing the first and second sleep laboratory night, a significant first-night effect was observed across both groups in the great majority of the investigated polysomnographic and subjective variables. However, patients with primary insomnia and good sleeper controls did not differ with respect to this effect. Regarding the comparison between the sleep laboratory nights and the home setting, unlike good sleeper controls, patients with primary insomnia reported an increased subjective sleep efficiency on both nights (in part due to a reduced bed time) and an increased subjective total sleep time on the second night. These results suggest that even the second sleep laboratory night does not necessarily provide clinicians and researchers with a representative insight into the sleep perception of patients with primary insomnia. Future studies should investigate whether these findings also hold for other patient populations. © 2015 European Sleep Research Society.

  11. Smoking, Screen-Based Sedentary Behavior, and Diet Associated with Habitual Sleep Duration and Chronotype: Data from the UK Biobank.

    Science.gov (United States)

    Patterson, Freda; Malone, Susan Kohl; Lozano, Alicia; Grandner, Michael A; Hanlon, Alexandra L

    2016-10-01

    Sleep duration has been implicated in the etiology of obesity but less is known about the association between sleep and other behavioral risk factors for cardiovascular disease. The aim of this study was to examine the associations among sleep duration, chronotype, and physical activity, screen-based sedentary behavior, tobacco use, and dietary intake. Regression models were used to examine sleep duration and chronotype as the predictors and cardiovascular risk factors as outcomes of interest in a cross-sectional sample of 439,933 adults enrolled in the UK Biobank project. Short sleepers were 45 % more likely to smoke tobacco than adequate sleepers (9.8 vs. 6.9 %, respectively). Late chronotypes were more than twice as likely to smoke tobacco than intermediate types (14.9 vs. 7.4 %, respectively). Long sleepers reported 0.61 more hours of television per day than adequate sleepers. Early chronotypes reported 0.20 fewer daily hours of computer use per day than intermediate chronotypes. Early chronotypes had 0.25 more servings of fruit and 0.13 more servings of vegetables per day than late chronotypes. Short and long sleep duration and late chronotype are associated with greater likelihood of cardiovascular risk behaviors. Further work is needed to determine whether these findings are maintained in the context of objective sleep and circadian estimates, and in more diverse samples. The extent to which promoting adequate sleep duration and earlier sleep timing improves heart health should also be examined prospectively.

  12. Effect of a warm footbath before bedtime on body temperature and sleep in older adults with good and poor sleep: an experimental crossover trial.

    Science.gov (United States)

    Liao, Wen-Chun; Wang, Lee; Kuo, Ching-Pyng; Lo, Chyi; Chiu, Ming-Jang; Ting, Hua

    2013-12-01

    The decrease in core body temperature before sleep onset and during sleep is associated with dilation of peripheral blood vessels, which permits heat dissipation from the body core to the periphery. A lower core temperature coupled with a higher distal (hands and feet) temperature before sleep are associated with shorter sleep latency and better sleep quality. A warm footbath is thought to facilitate heat dissipation to improve sleep outcomes. This study examined the effect of a warm footbath (40°C water temperature, 20-min duration) on body temperature and sleep in older adults (≥55 years) with good and poor sleep. Two groups and an experimental crossover design was used. Forty-three adults responded to our flyer and 25 participants aged 59.8±3.7 years (poor sleeper with a Pittsburgh Sleep Quality Index score≥5=17; good sleepers with a Pittsburgh Sleep Quality Index scoretemperatures (core, abdomen, and foot) and polysomnography recorded for 3 consecutive nights. The first night was for adaptation and sleep apnea screening. Participants were then randomly assigned to either the structured foot bathing first (second night) and non-bathing second (third night) condition or the non-bathing first (second night) and foot bathing second (third night) condition. A footbath before sleep significantly increased and retained foot temperatures in both good and poor sleepers. The pattern of core temperatures during foot bathing was gradually elevated (poor sleepers vs. good sleepers=+0.40±0.58°C vs. +0.66±0.17°C). There were no significant changes in polysomnographic sleep and perceived sleep quality between non-bathing and bathing nights for both groups. A footbath of 40°C water temperature and 20-min duration before sleep onset increases foot temperatures and distal-proximal skin temperature gradients to facilitate vessel dilatation and elevates core temperature to provide heat load to the body. This footbath does not alter sleep in older adults with good and

  13. Heritability and mortality risk of insomnia-related symptoms: a genetic epidemiologic study in a population-based twin cohort.

    Science.gov (United States)

    Hublin, Christer; Partinen, Markku; Koskenvuo, Markku; Kaprio, Jaakko

    2011-07-01

    Our aim was to estimate heritability in phenotypic insomnia and the association between insomnia and mortality. Representative follow-up study. 1990 survey of the Finnish Twin Cohort (N = 12502 adults; 1554 monozygotic and 2991 dizygotic twin pairs). Current insomnia-related symptoms (insomnia in general, difficulty in initiating sleep, sleep latency, nocturnal awakening, early morning awakening, and non-restorative sleep assessed in the morning and during the day) were asked. Latent class analysis was used to classify subjects into different sleep quality classes. Quantitative genetic modelling was used to estimate heritability. Mortality data was obtained from national registers until end of April 2009. The heritability estimates of each symptom were similar in both genders varying from 34% (early morning awakening) to 45% (nocturnal awakening). The most parsimonious latent class analysis produced 3 classes: good sleepers (48%), average sleepers (up to weekly symptoms, 40%), and poor sleepers (symptoms daily or almost daily, 12%). The heritability estimate for the cluster was 46% (95% confidence interval 41% to 50%). In a model adjusted for smoking, BMI, and depressive symptoms, the all-cause mortality of poor sleepers was elevated (excess mortality 55% in men and 51% in women). Further adjustment for sleep length, use of sleep promoting medications, and sleep apnea-related symptoms did not change the results. Insomnia-related symptoms were common in both genders. The symptoms and their clusters showed moderate heritability estimates. A significant association was found between poor sleep and risk of mortality, especially in those with somatic disease.

  14. Monthly Fluctuations of Insomnia Symptoms in a Population-Based Sample

    Science.gov (United States)

    Morin, Charles M.; LeBlanc, M.; Ivers, H.; Bélanger, L.; Mérette, Chantal; Savard, Josée; Jarrin, Denise C.

    2014-01-01

    Study Objectives: To document the monthly changes in sleep/insomnia status over a 12-month period; to determine the optimal time intervals to reliably capture new incident cases and recurrent episodes of insomnia and the likelihood of its persistence over time. Design: Participants were 100 adults (mean age = 49.9 years; 66% women) randomly selected from a larger population-based sample enrolled in a longitudinal study of the natural history of insomnia. They completed 12 monthly telephone interviews assessing insomnia, use of sleep aids, stressful life events, and physical and mental health problems in the previous month. A total of 1,125 interviews of a potential 1,200 were completed. Based on data collected at each assessment, participants were classified into one of three subgroups: good sleepers, insomnia symptoms, and insomnia syndrome. Results: At baseline, 42 participants were classified as good sleepers, 34 met criteria for insomnia symptoms, and 24 for an insomnia syndrome. There were significant fluctuations of insomnia over time, with 66% of the participants changing sleep status at least once over the 12 monthly assessments (51.5% for good sleepers, 59.5% for insomnia syndrome, and 93.4% for insomnia symptoms). Changes of status were more frequent among individuals with insomnia symptoms at baseline (mean = 3.46, SD = 2.36) than among those initially classified as good sleepers (mean = 2.12, SD = 2.70). Among the subgroup with insomnia symptoms at baseline, 88.3% reported improved sleep (i.e., became good sleepers) at least once over the 12 monthly assessments compared to 27.7% whose sleep worsened (i.e., met criteria for an insomnia syndrome) during the same period. Among individuals classified as good sleepers at baseline, risks of developing insomnia symptoms and syndrome over the subsequent months were, respectively, 48.6% and 14.5%. Monthly assessment over an interval of 6 months was found most reliable to estimate incidence rates, while an

  15. Six days on the road? Never again : service industry appeals to producers for help resolving hours of service issues

    Energy Technology Data Exchange (ETDEWEB)

    Lorenz, A.W.

    2007-04-15

    Road accidents are a leading cause of work-related deaths in western Canada. Northern Alberta has 3 times as many motor vehicle accidents per capita as the rest of the province. The federal government has heavily invested in the development of new rules mandating the amount of rest that drivers are now required to have before driving vehicles. However, the rules impose restrictions that difficult for oilfield workers to adhere to. The new rules reduce the maximum number of hours a worker may work, and state that workers must have 1 or 3 days off every 7 or 14 days. Workers in the oil and gas industry often need to travel long distances to remote areas where sleep accommodations are not available. Under the new standard, waiting time on location cannot be considered as off-duty, and drivers are not allowed to clock standby time as off-duty, nor are they permitted to sleep in the truck's sleeper berth on lease sites. Many trucks are not equipped with sleeper berths, and there is currently a critical shortage of motel accommodations in Alberta. A recent meeting conducted by various agencies to address the new driving standards has resulted in a request for sleeper berth permits. The agencies will also provide an effective means of verifying that a driver has had access to sleeping accommodation under the terms of the suggested sleeper berth alternative. It was concluded that if Transport Canada agrees to give Alberta the authority to grant permits, it will help to resolve issues unique to Alberta's oilfield contractors. 2 figs.

  16. Good and Bad Sleep in Childhood: A Questionnaire Survey amongst School Children in Southern Italy.

    Science.gov (United States)

    Ficca, Gianluca; Conte, Francesca; De Padova, Vittoria; Zilli, Iole

    2011-01-01

    Despite its clinical importance, the issue of subjective sleep quality in children remains unexplored. Here we investigate, in school-aged children, the prevalence of bad sleep perception and its relationships with sleep habits and daytime functioning, to provide hints on its possible determinants. Subjective sleep perception, sleep habits, and daytime functioning were studied through a questionnaire survey in a sample of 482 children (6-12 yrs.). Being "bad sleeper" was reported by 6.9% of the sample. Compared to the "good sleepers", these subjects displayed shorter sleep duration on schooldays, longer sleep latencies, and a more pronounced evening preference, beyond more frequent insufficient sleep. Though no differences emerged in sleepiness, bad sleepers showed higher impairments in daytime functioning, indicated by more frequent depressed mood and impulsivity. These distinctive features might be very important to precociously detect those children who are possibly more vulnerable to sleep disturbances and whose sleep-wake rhythms evolution should be paid particular attention thereafter. "The good people sleep much better at night than the bad people.Of course, the bad people enjoy the waking hours much more"Woody Allen.

  17. Joint associations of insomnia and sleep duration with prevalent diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

    Science.gov (United States)

    Cespedes, Elizabeth M; Dudley, Katherine A; Sotres-Alvarez, Daniela; Zee, Phyllis C; Daviglus, Martha L; Shah, Neomi A; Talavera, Gregory A; Gallo, Linda C; Mattei, Josiemer; Qi, Qibin; Ramos, Alberto R; Schneiderman, Neil; Espinoza-Giacinto, Rebeca A; Patel, Sanjay R

    2016-05-01

    Inadequate sleep quantity and quality are associated with a higher risk of type 2 diabetes. This relationship is not well-examined in U.S. Hispanics/Latinos, and prior analyses may be confounded by sleep apnea. This cross-sectional study examined joint associations of sleep duration and insomnia with diabetes among diverse U.S. Hispanic/Latinos. Baseline data on sleep quantity and quality were obtained from 15,227 participants (mean age 41; range 18-74 years) from the Hispanic Community Health Study/Study of Latinos. Complex survey multinomial logistic regression was used to examine associations between prevalent diabetes and six phenotypes defined by cross-classifying sleep duration (short ≤6 h, average >6-9 h, long >9 h) and insomnia, adjusting for sex, age, site and Hispanic/Latino background interaction, education, physical activity, diet quality, and sleep apnea. In the weighted population, 14% had diabetes, 28% had insomnia, 9% were short sleepers, and 19% were long sleepers. Compared with those with average sleep and no insomnia, those with short sleep and insomnia were more likely to have diabetes (odds ratio [OR] 1.46; 95% confidence interval [CI] 1.02, 2.11). Average sleepers with insomnia (1.28; 95% CI 1.02, 1.61) and long sleepers without insomnia (1.33; 95% CI 1.07, 1.65) also had elevated odds of diabetes. Further adjustment for body mass index attenuated associations, except with long sleep without insomnia. Both decreased quantity and quality of sleep are associated with diabetes in Hispanic/Latinos, with the greatest odds among those with short sleep duration and insomnia. The association is largely explained by obesity. © 2015 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.

  18. Development of standard weight equations for Caribbean and Gulf of Mexico amphidromous fishes

    Science.gov (United States)

    Cooney, Patrick B.; Kwak, Thomas J.

    2010-01-01

    We collected and compiled length and weight information from four countries and one commonwealth to develop standard weight (Ws) equations for three amphidromous fish species native to the Caribbean and Gulf of Mexico regions: mountain mullet Agonostomus monticola (N = 9,768 individuals, 52 populations), river goby Awaous banana (N = 1,847 individuals, 62 populations), and bigmouth sleeper Gobiomorus dormitor (N = 2,983 individuals, 53 populations). Linear and quadratic Ws equations for three quartiles (25%, median, 75%) are presented for these three species. The length-weight relationship from eight lentic bigmouth sleeper populations was significantly different from that of lotic populations, reflecting higher weights of juvenile fish (sport fisheries and allow ecological assessment based on fish condition.

  19. Railway diagnosis of electric transport

    Directory of Open Access Journals (Sweden)

    Yushkov Vladimir Sergeevich

    2015-01-01

    Full Text Available The increase in noise level at cities is increasing the requirements to functional interaction of road users - pedestrians and drivers - with the parameters of the environment as a leading component of Afferentation synthesis in the complicated complex of locomotive activity. City noise is one of the most widespread factors of unfavorable living and working conditions. The noise of high intensity provokes diseases, lowers labor activity. At present, many large cities pay much attention to electric vehicles. The authors present an analysis of the poor state of tram track in areas of high noise and vibration of car and under-sleeper base design. A negative effect of noise and vibration on the formation of urban areas environment is shown as well as the impact of these conditions on the person. The advantages of the application of electric transport are specified, noise displacement curve of railway and under sleeper base is plotted depending on the frequency of the applied load and the modulus of elasticity, as well as under sleeper base vibroacceleration depending on time. The authors offer a systematic study on the basis of a mathematical model of the sources of noise in the process of a tram motion.

  20. Sound : Albumid, singlid / Ülo Külm

    Index Scriptorium Estoniae

    Külm, Ülo

    1998-01-01

    Uutest albumitest Helloween "Better than raw", Primus "Rhinoplasty", Unbelievable Truth "Almost here", Dallas "Sleepers entertainer" (eesti), Massive Attack "Mezzanine" ja singlist Busta Rhymes "Turn it up /Fire it up"

  1. Sleeper in the string; Schlaefer im String

    Energy Technology Data Exchange (ETDEWEB)

    Schwarzburger, Heiko

    2013-11-01

    The number of overvoltage damage caused by lightning rise in the solar modules. Frequently affected are the junction boxes of the solar modules. In the junction box, it is mainly the bypass diodes that fail under surge. Very often the junction box appears from the outside intact. ''If the diodes are damaged, they are either conducting, or block them permanently,'' says Jan Zornikau, technical director of the Berlin Envaris GmbH. Envaris is a service provider who specializes in the replacement and repair of defective photovoltaic components. [German] Die Zahl der Ueberspannungsschaeden durch Blitze an den Solarmodulen steigen. Haeufig betroffen sind die Anschlussdosen der Solarmodule. In den Anschlussdosen sind es vor allem die Bypassdioden, die unter Ueberspannung versagen, wobei oft die Anschlussdose von aussen intakt erscheint. ''Wenn die Dioden beschaedigt sind, werden sie entweder leitend, oder sie sperren dauerhaft'', erlaeutert Jan Zornikau, Technikchef der Berliner Envaris GmbH. Envaris ist ein Dienstleister, der sich auf den Austausch und die Reparatur defekter Photovoltaikkomponenten spezialisiert hat. Das kann man nur herausfinden, indem man die einzelnen Module genau ausmisst und dabei einzelne Zellen abdeckt.

  2. Stress and sleep disturbances in female college students.

    Science.gov (United States)

    Lee, Shih-Yu; Wuertz, Caroline; Rogers, Rebecca; Chen, Yu-Ping

    2013-11-01

    To describe the sleep characteristics and examine the associations among perceived stress, sleep disturbances, depressive symptoms, and physical symptoms among female college students. A total of 103 students completed a battery of questionnaires. The students experienced high stress during the school year. The majority of them slept less than 6 hours during weekdays and experienced moderate fatigue. High stress levels are associated with sleep disturbances, less nocturnal total sleep time, higher fatigue severity, and more depressive symptoms. Perceived stress and sleep disturbances are significant predictors for depressive symptoms and physical symptoms. Compared to the good sleepers, the poor sleepers reported more daytime sleepiness, depressive symptoms, and physical symptoms. Interventions to reduce stress and improve sleep are critically needed in college education.

  3. Sleep quality and health-related quality of life among long-term survivors of (non-) Hodgkin lymphoma in Germany.

    Science.gov (United States)

    Hammersen, Friederike; Lewin, Philip; Gebauer, Judith; Kreitschmann-Andermahr, Ilonka; Brabant, Georg; Katalinic, Alexander; Waldmann, Annika

    2017-01-01

    This study investigated sleep quality and health-related quality of life (HRQOL) among long-term survivors of Hodgkin (HL) and non-Hodgkin lymphoma (NHL). The aim was to explore the impact of personal and health-related factors on sleep quality as well as associations between sleep quality and HRQOL. For the postal survey, participants with a minimum age of 18 years initially treated between 1998 and 2008 were recruited via the population-based cancer registry in Schleswig-Holstein, Northern Germany. Questionnaires included amongst others the Pittsburg Sleep Quality Index (PSQI) and the 36-Item Short Form Health Survey (SF-36v1). Descriptive and comparative statistics were performed. Additionally, a regression analysis was conducted to identify predictors of sleep quality. In total, we recruited 515 participants (398 NHL, 117 HL) with a mean age of 63.1 years. Approximately half of the survivors were classified as good sleepers. HRQOL scores differed between good and poor sleepers with lower scores in poor sleepers. In a prediction model, self-reported depression, exhaustion, higher age, inability to work, endocrinological disorders and female gender classified as predictors of sleep quality. This study highlights the impact of sleep quality on HRQOL in long-term survivors of NHL and HL. Thus, sleep quality should be routinely assessed during follow-up of cancer survivors with special attention to patients with potential risk factors.

  4. Perceived fitness protects against stress-based mental health impairments among police officers who report good sleep.

    Science.gov (United States)

    Gerber, Markus; Kellmann, Micheal; Elliot, Catherine; Hartmann, Tim; Brand, Serge; Holsboer-Trachsler, Edith; Pühse, Uwe

    2014-01-01

    This study examined a cognitive stress-moderation model that posits that the harmful effects of chronic stress are decreased in police officers who perceive high levels of physical fitness. It also determined whether the stress-buffering effect of perceived fitness is influenced by officers' self-reported sleep. A total of 460 police officers (n=116 females, n=344 males, mean age: M=40.7; SD=9.7) rated their physical fitness and completed a battery of self-report stress, mental health, and sleep questionnaires. Three-way analyses of covariance were performed to examine whether officers' self-reported mental health status depends on the interaction between stress, perceived fitness and sleep. Highly stressed officers perceived lower mental health and fitness and were overrepresented in the group of poor sleepers. Officers with high fitness self-reports revealed increased mental health and reported good sleep. In contrast, poor sleepers scored lower on the mental health index. High stress was more closely related to low mental health among poor sleepers. Most importantly, perceived fitness revealed a stress-buffering effect, but only among officers who reported good sleep. High perceived fitness and good sleep operate as stress resilience resources among police officers. The findings suggest that multimodal programs including stress management, sleep hygiene and fitness training are essential components of workplace health promotion in the police force.

  5. Subjective sleep complaints indicate objective sleep problems in psychosomatic patients: a prospective polysomnographic study

    Directory of Open Access Journals (Sweden)

    Linden M

    2016-08-01

    Full Text Available Michael Linden,1,2 Marie Dietz,1 Christian Veauthier,3 Ingo Fietze3 1Research Group Psychosomatic Rehabilitation, Charité University Medicine Berlin, 2Department of Psychosomatic Medicine, Rehabilitation Centre Seehof, Teltow, 3Interdisciplinary Center of Sleep Medicine, Charité University Medicine Berlin, Berlin, Germany Objective: To elucidate the relationship between subjective complaints and polysomnographical parameters in psychosomatic patients.Method: A convenience sample of patients from a psychosomatic inpatient unit were classified according to the Pittsburgh Sleep Quality Index (PSQI as very poor sleepers (PSQI >10, n=80 and good sleepers (PSQI <6, n=19. They then underwent a polysomnography and in the morning rated their previous night’s sleep using a published protocol (Deutschen Gesellschaft für Schlafforschung und Schlafmedizin morning protocol [MP].Results: In the polysomnography, significant differences were found between very poor and good sleepers according to the PSQI with respect to sleep efficiency and time awake after sleep onset. When comparing objective PSG and subjective MP, the polysomnographical sleep onset latency was significantly positively correlated with the corresponding parameters of the MP: the subjective sleep onset latency in minutes and the subjective evaluation of sleep onset latency (very short, short, normal, long, very long were positively correlated with the sleep latency measured by polysomnography. The polysomnographical time awake after sleep onset (in minutes was positively correlated with the subjective time awake after sleep onset (in minutes, evaluation of time awake after sleep onset (seldom, normal often, and subjective restfulness. The polysomnographical total sleep time (TST was positively correlated with the subjective TST. Conversely, the polysomnographical TST was negatively correlated with the evaluation of TST (high polysomnographical TST was correlated with the subjective

  6. Sleep Management Strategy and Performance in an Extreme Mountain Ultra-marathon.

    Science.gov (United States)

    Poussel, Mathias; Laroppe, Julien; Hurdiel, Rémy; Girard, Julien; Poletti, Laurence; Thil, Catherine; Didelot, Antoine; Chenuel, Bruno

    2015-01-01

    We intended to assess the relationship between sleep strategies and performance during the North-Face Ultra-Trail du Mont-Blanc 2013, to test the hypothesis that sleep management can influence athletic performance. Almost all runners specifically adopted sleep management strategies before the race. Among the finishers 72% didn't sleep at all during the race and 28% took a least one break for sleep. Non-sleepers completed the race faster than the sleepers (P = 0.0008). Race time was positively correlated with drowsiness (P sleep management strategy based on increased sleep time before the race completed the race faster (P = 0.0258). Most finishers seemed to be aware of the importance of developing sleep management strategies and increasing sleep time some nights before the race appeared to be the most relevant strategy to improve performance.

  7. The relationship between sleep duration and fruit/vegetable intakes in UK adults: a cross-sectional study from the National Diet and Nutrition Survey

    Science.gov (United States)

    Cade, Janet E; Burley, Victoria J; Hardie, Laura J

    2018-01-01

    Objectives There is increasing evidence to suggest an association between sleep and diet. The aim of the present study was to examine the association between sleep duration and fruit/vegetable (FV) intakes and their associated biomarkers in UK adults. Design Cross-sectional. Setting Data from The National Diet and Nutrition Survey. Participants 1612 adults aged 19–65 years were included, pregnant/breastfeeding women were excluded from the analyses. Outcome measures Sleep duration was assessed by self-report, and diet was assessed by 4-day food diaries, disaggregation of foods containing FV into their components was conducted to determine total FV intakes. Sleep duration was divided into: short (8 hours/day) sleep periods. Multiple regression adjusting for confounders was used for analyses where sleep duration was the exposure and FV intakes and their associated biomarkers were the outcomes. Restricted cubic spline models were developed to explore potential non-linear associations. Results In adjusted models, long sleepers (LS) consumed on average 28 (95% CI −50 to −6, p=0.01) g/day less of total FV compared to reference sleepers (RS), whereas short sleepers (SS) consumed 24 g/day less (95% CI −42 to –6, p=0.006) and had lower levels of FV biomarkers (total carotenoids, β-carotene and lycopene) compared to RS. Restricted cubic spline models showed that the association between sleep duration and FV intakes was non-linear (pimportant implications for lifestyle and behavioural change policy. PMID:29703857

  8. The role of emotional eating and stress in the influence of short sleep on food consumption.

    Science.gov (United States)

    Dweck, Julia S; Jenkins, Steve M; Nolan, Laurence J

    2014-01-01

    Short sleep duration is associated with elevated body mass index (BMI) and increased energy consumption. The present studies were conducted to determine what role emotional eating and stress might play in these relationships. The first was an exploratory questionnaire study in which sleep quality and duration were measured in conjunction with the Dutch Eating Behavior Questionnaire in 184 women. Emotional and external eating scores were significantly higher in those who reported poor sleep quality (but were not related to sleep duration). In a second study of 64 women who were provided with snacks in the laboratory under stressed and control conditions, elevated food consumption was observed in those who scored high on emotional eating and who reported short sleep (a significant stress × emotional eating × sleep duration interaction) but not in those who reported poor sleep quality. No effects were found in liking or wanting of food and few effects were found on appetite. BMI was not related to sleep duration or sleep quality in either study. The results suggest that the relationship between short sleep and elevated food consumption exists in those who are prone to emotional eating. An external stressor elevated consumption in normal sleepers to the level observed in short sleepers, however, it did not significantly elevate consumption in short sleepers. Future examinations of the effects of sleep duration and quality on food consumption should examine emotional eating status. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Transitions in sleep problems from late adolescence to young adulthood: A longitudinal analysis of the effects of peer victimization.

    Science.gov (United States)

    Chang, Ling-Yin; Chang, Hsing-Yi; Lin, Linen Nymphas; Wu, Chi-Chen; Yen, Lee-Lan

    2018-01-01

    Adolescence is a developmental period with high vulnerability to sleep problems. However, research identifying distinct patterns and underlying determinants of sleep problems is scarce. This study investigated discrete subgroups of, changes in, and stability of sleep problems. We also examined whether peer victimization influenced sleep problem subgroups and transitions in patterns of sleep problems from late adolescence to young adulthood. Sex differences in the effects of peer victimization were also explored. In total, 1,455 male and 1,399 female adolescents from northern Taiwan participated in this longitudinal study. Latent transition analysis was used to examine changes in patterns of sleep problems and the effects of peer victimization on these changes. We identified three subgroups of sleep problems in males and two in females, and found that there was a certain level of instability in patterns of sleep problems during the study period. For both sexes, those with greater increases in peer victimization over time were more likely to change from being a good sleeper to a poor sleeper. The effects of peer victimization on baseline status of sleep problems, however, was only significant for males, with those exposed to higher levels of peer victimization more likely to be poor sleepers at baseline. Our findings reveal an important role of peer victimization in predicting transitions in patterns of sleep problems. Intervention programs aimed at decreasing peer victimization may help reduce the development and escalation of sleep problems among adolescents, especially in males. © 2017 Wiley Periodicals, Inc.

  10. Environmental Assessment of the Relocation of a Weather Training Facility to Keesler Air Force Base, Biloxi, Mississippi

    Science.gov (United States)

    1989-09-15

    Notropis venustus Blacktail shiner A Ogcocephalus nasutus Shortnose batfish R Oligoplites saurus * Leatherjacket C Ophichthus gomesi Shrimp eel A...petenense Threadfin shad A Echeneis naucrates Sharksucker R Eleotris pisonis Spinycheek sleeper C Elops saurus Ladyfish A Epirephelus drummondhayi

  11. Proposal of Screening Method of Sleep Disordered Breathing Using Fiber Grating Vision Sensor

    Science.gov (United States)

    Aoki, Hirooki; Nakamura, Hidetoshi; Nakajima, Masato

    Every conventional respiration monitoring technique requires at least one sensor to be attached to the body of the subject during measurement, thereby imposing a sense of restraint that results in aversion against measurements that would last over consecutive days. To solve this problem, we developed a respiration monitoring system for sleepers, and it uses a fiber-grating vision sensor, which is a type of active image sensor to achieve non-contact respiration monitoring. In this paper, we verified the effectiveness of the system, and proposed screening method of the sleep disordered breathing. It was shown that our system could equivalently measure the respiration with thermistor and accelerograph. And, the respiratory condition of sleepers can be grasped by our screening method in one look, and it seems to be useful for the support of the screening of sleep disordered breathing.

  12. Framework for Railway Phase-based Planning

    DEFF Research Database (Denmark)

    Li, Rui; Landex, Alex; Nielsen, Otto Anker

    spending) to evaluate the project alternatives. The comparison result can identify the most cost-efficient solution in a long run and therefore reduce the overall costs. This article defines a phase-based framework to guide the railway maintenance and renewal project planning at strategic level....... The framework evaluates the project options from a larger LCC scope: The costs from train operation companies and passengers, together with the maintenance and renewal costs from Infrastructure Managers are included in the calculation. The framework simplifies the planning processes and the LCC calculation...... and compared. A case study is introduced in the article to demonstrate how the framework works to compare timber sleepers and concrete sleepers from strategic planning level. Two Life Cycle Cost oriented policies are discussed to illustrate: high quality track is necessity to improve the cost efficiency...

  13. 77 FR 73345 - Safety Standard for Bedside Sleepers

    Science.gov (United States)

    2012-12-10

    ... durable infant or toddler products, in consultation with representatives of consumer groups, juvenile... Commission (Commission or CPSC) to promulgate consumer product safety standards for durable infant or toddler... marking, labeling, and instructional literature of the proposed rule should be directed to the Office of...

  14. Determinants of perceived sleep quality in normal sleepers.

    Science.gov (United States)

    Goelema, M S; Regis, M; Haakma, R; van den Heuvel, E R; Markopoulos, P; Overeem, S

    2017-09-20

    This study aimed to establish the determinants of perceived sleep quality over a longer period of time, taking into account the separate contributions of actigraphy-based sleep measures and self-reported sleep indices. Fifty participants (52 ± 6.6 years; 27 females) completed two consecutive weeks of home monitoring, during which they kept a sleep-wake diary while their sleep was monitored using a wrist-worn actigraph. The diary included questions on perceived sleep quality, sleep-wake information, and additional factors such as well-being and stress. The data were analyzed using multilevel models to compare a model that included only actigraphy-based sleep measures (model Acti) to a model that included only self-reported sleep measures to explain perceived sleep quality (model Self). In addition, a model based on the self-reported sleep measures and extended with nonsleep-related factors was analyzed to find the most significant determinants of perceived sleep quality (model Extended). Self-reported sleep measures (model Self) explained 61% of the total variance, while actigraphy-based sleep measures (model Acti) only accounted for 41% of the perceived sleep quality. The main predictors in the self-reported model were number of awakenings during the night, sleep onset latency, and wake time after sleep onset. In the extended model, the number of awakenings during the night and total sleep time of the previous night were the strongest determinants of perceived sleep quality, with 64% of the variance explained. In our cohort, perceived sleep quality was mainly determined by self-reported sleep measures and less by actigraphy-based sleep indices. These data further stress the importance of taking multiple nights into account when trying to understand perceived sleep quality.

  15. Relationships between questionnaire ratings of sleep quality and polysomnography in healthy adults

    NARCIS (Netherlands)

    Westerlund, A.; Trolle-Lagerros, Y.; Kecklund, L.G.; Axelsson, J.; Akerstedt, T.

    2016-01-01

    This study aimed to examine the association between polysomnographic sleep and subjective habitual sleep quality and restoration from sleep. Thirty-one normal sleepers completed the Karolinska Sleep Questionnaire and multiple home polysomnography recordings (n = 2-5). Using linear regression, sleep

  16. Bridge approach slabs for Missouri DOT field evaluation of alternative and cost efficient bridge approach slabs.

    Science.gov (United States)

    2013-05-01

    Based on a recent study on cost efficient alternative bridge approach slab (BAS) designs (Thiagarajan et : al. 2010) has recommended three new BAS designs for possible implementation by MoDOT namely a) 20 feet cast-inplace : slab with sleeper slab (C...

  17. Restless Legs Syndrome -- Causes and Symptoms

    Science.gov (United States)

    ... miles): 10 25 50 Share: Essentials in Sleep Insomnia Overview & Facts Symptoms & Causes Diagnosis & Self Tests Treatment Sleep Apnea Overview & Facts ... Self Test & Diagnosis Treatment Snoring Overview and Facts Causes and Symptoms Self Tests & ... Insomnia Short Sleeper Hypersomnias Narcolepsy Insufficient ...

  18. Parasomnias

    Science.gov (United States)

    ... miles): 10 25 50 Share: Essentials in Sleep Insomnia Overview & Facts Symptoms & Causes Diagnosis & Self Tests Treatment Sleep Apnea Overview & Facts ... Self Test & Diagnosis Treatment Snoring Overview and Facts Causes and Symptoms Self Tests & ... Insomnia Short Sleeper Hypersomnias Narcolepsy Insufficient ...

  19. In-Home Sleep Recordings in Military Veterans With Posttraumatic Stress Disorder Reveal Less REM and Deep Sleep <1 Hz

    Directory of Open Access Journals (Sweden)

    Julie A. Onton

    2018-05-01

    Full Text Available Veterans with posttraumatic stress disorder (PTSD often report suboptimal sleep quality, often described as lack of restfulness for unknown reasons. These experiences are sometimes difficult to objectively quantify in sleep lab assessments. Here, we used a streamlined sleep assessment tool to record in-home 2-channel electroencephalogram (EEG with concurrent collection of electrodermal activity (EDA and acceleration. Data from a single forehead channel were transformed into a whole-night spectrogram, and sleep stages were classified using a fully automated algorithm. For this study, 71 control subjects and 60 military-related PTSD subjects were analyzed for percentage of time spent in Light, Hi Deep (1–3 Hz, Lo Deep (<1 Hz, and rapid eye movement (REM sleep stages, as well as sleep efficiency and fragmentation. The results showed a significant tendency for PTSD sleepers to spend a smaller percentage of the night in REM (p < 0.0001 and Lo Deep (p = 0.001 sleep, while spending a larger percentage of the night in Hi Deep (p < 0.0001 sleep. The percentage of combined Hi+Lo Deep sleep did not differ between groups. All sleepers usually showed EDA peaks during Lo, but not Hi, Deep sleep; however, PTSD sleepers were more likely to lack EDA peaks altogether, which usually coincided with a lack of Lo Deep sleep. Linear regressions with all subjects showed that a decreased percentage of REM sleep in PTSD sleepers was accounted for by age, prazosin, SSRIs and SNRIs (p < 0.02, while decreased Lo Deep and increased Hi Deep in the PTSD group could not be accounted for by any factor in this study (p < 0.005. Linear regression models with only the PTSD group showed that decreased REM correlated with self-reported depression, as measured with the Depression, Anxiety, and Stress Scales (DASS; p < 0.00001. DASS anxiety was associated with increased REM time (p < 0.0001. This study shows altered sleep patterns in sleepers with PTSD that can be partially accounted

  20. The burden of insomnia in Japan

    Directory of Open Access Journals (Sweden)

    Mishima K

    2015-01-01

    Full Text Available Kazuo Mishima,1 Marco daCosta DiBonaventura,2 Hillary Gross2 1Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan; 2Kantar Health, New York, NY, USA Objectives: Several studies have suggested that patients who experience insomnia report a number of significant impairments. However, despite this literature, fewer studies have focused on the burden of insomnia among patients in Japan. The objective of the current study is to extend this work in Japan to further understand the effect of insomnia on health-related quality of life (hrQOL. Further, another objective is to understand general predictors of hrQOL among patients with insomnia. Methods: Data from the 2012 Japan National Health and Wellness Survey, an annual, cross-sectional study of adults aged 18 years or older, were used (N=30,000. All National Health and Wellness Survey respondents were categorized based on the incidence of self-reported insomnia diagnosis and prescription medication usage (clinical insomniacs under treatment versus [vs] good sleepers without insomnia or insomnia symptoms. Comparisons among different groups were made using multiple regression models controlling for demographics and health history. Results: Clinical insomniacs (n=1,018; 3.4% reported significantly worse hrQOL compared with good sleepers (n=20,542 (mental component summary: 34.2 vs 48.0; physical component summary: 48.0 vs 52.8; health utilities: 0.61 vs 0.76; all P<0.05. Health behaviors (smoking, exercise, alcohol use and comorbidities were the strongest predictors of health utilities for clinical insomniacs. For all three clinical insomniac subgroups of interest, those with a physical comorbidity but not a psychiatric one, those with a psychiatric comorbidity but not a physical one, and those without either a physical or psychiatric comorbidity, large decrements in health utilities were observed for respondents who did

  1. Investigation on dysfunctional beliefs and attitudes about sleep in Chinese college students

    Directory of Open Access Journals (Sweden)

    Jin LR

    2018-06-01

    Full Text Available Lairun Jin,1 Jun Zhou,1 Hui Peng,2 Shushu Ding,1 Hui Yuan1 1School of Public Health, Wannan Medical College, Wuhu, Anhui, People’s Republic of China; 2Department of Hospital Infection Management, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, People’s Republic of China Objective: The aims of this study were to evaluate a subset of sleep-related cognitions and to examine whether dysfunctional beliefs and attitudes about sleep were associated with sleep quality in college students. Patients and methods: A total of 1,333 college students were enrolled in this study by randomized cluster sampling. A brief version of Dysfunctional Beliefs and Attitudes about Sleep Scale (DBAS-16 was administered to college students at several colleges. Sleep quality was also assessed using the Pittsburgh Sleep Quality Index (PSQI. The DBAS-16 scores were analyzed across different demographic variables, corresponding subscales of 7-item PSQI, and relevant sleep behavior variables. Results: A total of 343 participants were poor sleepers, while 990 were good sleepers, as defined by PSQI. The DBAS-16 scores were lower in poor sleepers than in good sleepers (46.32 ± 7.851 vs 49.87 ± 8.349, p < 0.001, and DBAS-16 scores were lower in females and nonmedical students when compared with those in males and medical students, respectively (48.20 ± 8.711 vs 49.73 ± 7.923, p = 0.001; 48.56 ± 8.406 vs 49.88 ± 8.208, p = 0.009, respectively. The total score for sleep quality, as measured by PSQI, was negatively correlated with the DBAS-16 total score (r = −0.197, p < 0.01. There were significant differences in PSQI scores between individuals with attitudes and those without attitudes about sleep with respect to good sleep habits (p < 0.001, self-relaxation (p = 0.001, physical exercise (p < 0.001, taking sleeping pills (p = 0.004, and taking no action (p < 0.001. Conclusion: Dysfunctional beliefs about sleep are associated with sleep quality and should be

  2. Pop / Erkki Luuk

    Index Scriptorium Estoniae

    Luuk, Erkki, 1971-

    2003-01-01

    Heliplaatidest: Lionel Marchetti "RISS (l'avalanche)", Scooter "The Stadium Techno Experience", Kojak "Every Room On Every Floor", Mike Oldfield "Tubular Bells 2003", Stereophonics "You Gotta Go There To Come Back", Sleepy Sleepers "Kekkonen", M Ward "Transfiguratuon Of Vincent", Molotov "Dance And Dense Denso"

  3. Sleep disturbances, body fat distribution, food intake and/or energy expenditure: pathophysiological aspects

    Science.gov (United States)

    Shechter, Ari

    2015-01-01

    Data from cross-sectional and longitudinal studies have illustrated a relationship between short sleep duration (SSD) and weight gain. Individuals with SSD are heavier and gain more weight over time than normal-duration sleepers. This sleep-obesity relationship may have consequences for obesity treatments, as it appears that short sleepers have reduced ability to lose weight. Laboratory-based clinical studies found that experimental sleep restriction affects energy expenditure and intake, possibly providing a mechanistic explanation for the weight gain observed in chronic short sleepers. Specifically, compared to normal sleep duration, sleep restriction increases food intake beyond the energetic costs of increased time spent awake. Reasons for this increased energy intake after sleep restriction are unclear but may include disrupted appetite-regulating hormones, altered brain mechanisms involved in the hedonic aspects of appetite, and/or changes in sleep quality and architecture. Obstructive sleep apnea (OSA) is a disorder at the intersection of sleep and obesity, and the characteristics of the disorder illustrate many of the effects of sleep disturbances on body weight and vice versa. Specifically, while obesity is among the main risk factors for OSA, the disorder itself and its associated disturbances in sleep quality and architecture seem to alter energy balance parameters and may induce further weight gain. Several intervention trials have shown that weight loss is associated with reduced OSA severity. Thus, weight loss may improve sleep, and these improvements may promote further weight loss. Future studies should establish whether increasing sleep duration/improving sleep quality can induce weight loss. PMID:25372728

  4. Sleep Habits and Susceptibility to Upper Respiratory Illness: the Moderating Role of Subjective Socioeconomic Status

    Science.gov (United States)

    Prather, Aric A.; Janicki-Deverts, Denise; Adler, Nancy E.; Hall, Martica; Cohen, Sheldon

    2016-01-01

    Background Sleep is a predictor of infectious illness that may depend on one’s socioeconomic status (SES). Purpose This study aimed to investigate the moderating effects of objective and subjective SES on sleep-clinical cold risk link and test whether nasal inflammation serves as a plausible biological pathway. Methods This study combined data (n = 732) from three viral challenge studies. Measures of self-reported sleep and objective and subjective measures of SES were obtained. Participants were quarantined and administrated rhinovirus (RV) or influenza virus and monitored over 5 (RV) or 6 (influenza) days for the development of a cold. Symptom severity, including mucus production and nasal clearance time, and levels of nasal cytokines (interleukin (IL)-6 and IL-1β) were measured prior to administration and each day during the quarantined period. Results Subjective SES, but not objective SES, moderated associations between shorter sleep duration and increased likelihood of a clinical cold. Compared to ≥8-hour sleepers, ≤6-hour sleepers with low subjective SES were at increased risk for developing a cold (OR = 2.57, 95% CI 1.10–6.02). There was no association between sleep duration and colds in high subjective SES participants. Among infected individuals who reported low subjective SES, shorter sleep duration was associated with greater mucus production. There was no evidence that markers of nasal inflammation mediated the link between sleep duration and cold susceptibility among those reporting low subjective SES. Conclusion Subjective SES may reflect an important social factor for understanding vulnerability to and protection against infectious illness among short sleepers. PMID:27679462

  5. Sleep and Food Choice in a Dutch Student Population

    NARCIS (Netherlands)

    Leenaars, Cathalijn H C; Klinkenberg, Inge P M; Aussems, Audrey; Borger, Nedim; Faatz, Vivian; Hak, Anneloes; Houben, Ellen; Ramackers, Joyce; Snackers, Daphne; Kalsbeek, A.

    2015-01-01

    BACKGROUND: The increased risk of obesity among short sleepers is most likely explained by increased energy intake. However, food intake could not only be altered quantitavely but also qualitatively. Therefore, we performed a correlational analysis on self-reported food intake and sleep in 51

  6. Sleep and Food Choice in a Dutch Student Population

    NARCIS (Netherlands)

    Leenaars, Cathalijn H. C.; Klinkenberg, Inge P. M.; Aussems, Audrey; Borger, Nedim; Faatz, Vivian; Hak, Anneloes; Houben, Ellen; Ramackers, Joyce; Snackers, Daphne; Kalsbeek, Andries

    2015-01-01

    The increased risk of obesity among short sleepers is most likely explained by increased energy intake. However, food intake could not only be altered quantitavely but also qualitatively. Therefore, we performed a correlational analysis on self-reported food intake and sleep in 51 students from

  7. Insomnia among Adolescents: Implications for Counselors.

    Science.gov (United States)

    Morrison, Jack R.

    Adolescent underachievers may be, in fact, victims of insomnia or other types of sleep disorders. Insomnia is a greatly overlooked affliction that affects approximately 13% of the adolescent population, creating daytime side-effects that could impair intellectual functioning, such as imposing learning constraints. Poor sleepers among the…

  8. Sleep Deprivation and Late Bedtime Impair Sperm Health Through Increasing Antisperm Antibody Production: A Prospective Study of 981 Healthy Men.

    Science.gov (United States)

    Liu, Mei-Mei; Liu, Li; Chen, Liang; Yin, Xiao-Jing; Liu, Hui; Zhang, Yan-Hua; Li, Pei-Ling; Wang, Shan; Li, Xiao-Xiao; Yu, Cai-Hong

    2017-04-16

    BACKGROUND The aim of this study was to investigate the effects of sleep duration and bedtime on sperm health, and the possible mechanism involved. MATERIAL AND METHODS We randomly divided 981 healthy Chinese men into groups according to research-set bedtimes (A=8-10 PM, B=after 10 PM, and C=after midnight) and sleep durations: group 1=average), and group 3=>9.0 h (long). Sperm morphology, count, survival, and motility were examined according to sleep patterns. Antisperm antibody (ASA) production in semen was determined. RESULTS Sperm counts and their survival rates were lower in the short sleepers as compared to others within each group (all Pcounts and survival rates were observed in different bedtimes, with significant differences found between measurements of C1 vs. A1 and C2 vs. A2 or B2 (all Paverage and long sleepers (all Psperm health in the study cohort, partly through increasing ASA production in the semen.

  9. Using Mid-Sleep Time to Determine Chronotype in Young Adults with Insomnia-Related Symptoms

    Directory of Open Access Journals (Sweden)

    Sooyeon Suh

    2017-12-01

    Full Text Available The Munich Chronotype Questionnaire (MCTQ uses sleep behavior to assess chronotype, but the extent to which such sleep behavior based assessments might be useful in populations with sleep disorders, such as insomnia, is currently unclear. We thus systematically assessed sleep disorders, MCTQ and the Morningness-Eveningness Questionnaire (MEQ, another behavioral preferencebased assessment of chronotype, in 310 individuals. In a smaller substudy (n = 121, we compared the MCTQ to sleep diaries in insomnia patients and good sleepers. Insomnia patients had overall lower consistency in chronotypes compared to good sleepers on the MCTQ compared to the MEQ, which was also evident when compared to sleep diaries. As insomnia disorder is characterized by time gaps spent awake during the night due to difficulty maintaining sleep, there may be limitations in using mid-sleep time as an accurate indicator of chronotype in insomnia patients. Our study suggests that the MCTQ should be used in conjunction with another existing questionnaire or assessment tool when assessing chronotype in insomnia patients.

  10. Reduced anterior internal capsule white matter integrity in primary insomnia.

    Science.gov (United States)

    Spiegelhalder, Kai; Regen, Wolfram; Prem, Martin; Baglioni, Chiara; Nissen, Christoph; Feige, Bernd; Schnell, Susanne; Kiselev, Valerij G; Hennig, Jürgen; Riemann, Dieter

    2014-07-01

    Chronic insomnia is one of the most prevalent central nervous system diseases, however, its neurobiology is poorly understood. Up to now, nothing is known about the integrity of white matter tracts in insomnia patients. In this study, diffusion tensor imaging (DTI) was used in a well-characterized sample of primary insomnia (PI) patients and good sleeper controls to fill this void. Voxelwise between-group comparisons of fractional anisotropy (FA) were performed in 24 PI patients (10 males; 14 females; 42.7 ± 14.5 years) and 35 healthy good sleepers (15 males; 20 females; 40.1 ± 9.1 years) with age and sex as covariates. PI patients showed reduced FA values within the right anterior internal capsule and a trend for reduced FA values in the left anterior internal capsule. The results suggest that insomnia is associated with a reduced integrity of white matter tracts in the anterior internal capsule indicating that disturbed fronto-subcortical connectivity may be a cause or consequence of the disorder.

  11. Mathematical model of dynamic interaction between wheel-set and rail track

    Directory of Open Access Journals (Sweden)

    G. Bureika

    2002-04-01

    Full Text Available The main goal of this title is to show how the effects on maximum bending tensions at different locations in the track caused by simultaneous changes of the various parameters can be estimated in a rational manner The dynamic of vertical interaction between a moving rigid wheel and a flexible railway track is investigated. A round and smooth wheel tread and an initially straight and non-corrugated rail surface are assumed in the present optimisation study. Asymmetric linear three-dimensional beam structure model of a finite length of the track is suggested including rail, pads, sleepers and ballast with spatially non-proportional damping. Transient bending tensions in sleepers and rail are calculated. The influence of eight selected track parameters on the dynamic behaviour of the track is investigated. A two-level fractional factorial design method is used in the search for a combination of numerical levels of these parameters making the maximum bending tensions the minimum. Finally, the main conclusions are given.

  12. The Use of Deconstructed Tires as Elastic Elements in Railway Tracks.

    Science.gov (United States)

    Sol-Sánchez, Miguel; Moreno-Navarro, Fernando; Rubio-Gámez, Mª Carmen

    2014-08-18

    Elastic elements such as rail pads, under sleeper pads and under ballast mats are railway components that allow for a reduction in track deterioration and vibrations. And they are furthermore commonly used to obtain an optimal vertical stiffness of the infrastructure. However, the use of elastomeric materials can increase construction costs and the consumption of raw materials. Thus, the utilization of used tire layers offers an alternative to reuse an abundant waste reducing the cost of elastic elements. In addition, an innovator technique allows deconstructing tire layers without grinding up the material, reducing production costs at the same time that tire properties are remained. This research is focused on the study of the viability of developing elastic components from used tire layers by evaluating the influence of thickness, the resistance capacity of the elements and their behavior in a ballast box. Results indicate the ability of tire pads to manufacture elastic elements (rail pads, under sleeper pads and under ballast mats) to be used in railway tracks.

  13. Investigating psychological and physiological responses to the Trier Social Stress Test in young adults with insomnia.

    Science.gov (United States)

    Chen, Ivy Y; Jarrin, Denise C; Ivers, Hans; Morin, Charles M

    2017-12-01

    Stress and hyperarousal both contribute to insomnia. Elevated stress-related sleep reactivity is associated with hyperarousal, and might constitute a vulnerability to future insomnia. The present study examined acute stress-induced arousal and its association with nocturnal sleep. Participants were 30 healthy adults (66.7% female, M age  = 26.7 years): 10 with insomnia (INS) and 20 good sleepers with high vulnerability (HV) or low vulnerability (LV) to insomnia. They underwent two consecutive nights of polysomnography. During the evening preceding the second night, the Trier Social Stress Test (TSST) was administered, and psychological and physiological arousal indices were assessed. The TSST elicited an increase in psychological and physiological arousal in all three groups. The INS group showed greater acute cortisol response (p stress reactivity and bedtime hyperarousal might represent a trait-like vulnerability in certain good sleepers. More research is warranted to validate and expand these preliminary findings. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Purification and characterization of β-glucosidase from ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-12-17

    Dec 17, 2008 ... natural environments. However they are highly destruc- tive pest, causing significant economic losses through damage to timber-in-service such as building, poles, bridges and railway sleepers in addition to forest, fruit and ornamental trees (Su, 2002). The two most effective control options for subterranean ...

  15. Sleep patterns and predictors of disturbed sleep in a large population of college students.

    Science.gov (United States)

    Lund, Hannah G; Reider, Brian D; Whiting, Annie B; Prichard, J Roxanne

    2010-02-01

    To characterize sleep patterns and predictors of poor sleep quality in a large population of college students. This study extends the 2006 National Sleep Foundation examination of sleep in early adolescence by examining sleep in older adolescents. One thousand one hundred twenty-five students aged 17 to 24 years from an urban Midwestern university completed a cross-sectional online survey about sleep habits that included the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale, the Horne-Ostberg Morningness-Eveningness Scale, the Profile of Mood States, the Subjective Units of Distress Scale, and questions about academic performance, physical health, and psychoactive drug use. Students reported disturbed sleep; over 60% were categorized as poor-quality sleepers by the PSQI, bedtimes and risetimes were delayed during weekends, and students reported frequently taking prescription, over the counter, and recreational psychoactive drugs to alter sleep/wakefulness. Students classified as poor-quality sleepers reported significantly more problems with physical and psychological health than did good-quality sleepers. Students overwhelmingly stated that emotional and academic stress negatively impacted sleep. Multiple regression analyses revealed that tension and stress accounted for 24% of the variance in the PSQI score, whereas exercise, alcohol and caffeine consumption, and consistency of sleep schedule were not significant predictors of sleep quality. These results demonstrate that insufficient sleep and irregular sleep-wake patterns, which have been extensively documented in younger adolescents, are also present at alarming levels in the college student population. Given the close relationships between sleep quality and physical and mental health, intervention programs for sleep disturbance in this population should be considered. Copyright 2010 Society for Adolescent Medicine. Published by Elsevier Inc. All rights reserved.

  16. Attention-deficit/hyperactivity disorder dimensions and sluggish cognitive tempo symptoms in relation to college students' sleep functioning.

    Science.gov (United States)

    Becker, Stephen P; Luebbe, Aaron M; Langberg, Joshua M

    2014-12-01

    This study examined separate inattentive, hyperactive, and impulsive dimensions of attention-deficit/hyperactivity disorder (ADHD), as well as sluggish cognitive tempo (SCT) symptoms, in relation to college students' sleep functioning. Participants were 288 college students (ages 17-24; 65 % female; 90 % non-Hispanic White; 12 % self-reported having an ADHD diagnoses) who completed measures of ADHD/SCT symptoms and sleep functioning. Participants reported obtaining an average of 6.8 h of sleep per night (only 26 % reported obtaining ≥8 h of sleep) and having a sleep onset latency of 25 min. 63 % were classified as "poor sleepers," and poor sleepers had higher rates of ADHD and SCT symptoms than "good sleepers". Path analysis controlling for ADHD status and psychiatric medication use was used to determine associations between psychopathology and sleep functioning domains. Above and beyond covariates and other psychopathologies, hyperactivity (but not impulsivity) was significantly associated with poorer sleep quality, longer sleep latency, shorter sleep duration, and more use of sleep medications. SCT symptoms (but not inattention) were significantly associated with poorer sleep quality and increased nighttime sleep disturbance (e.g., having bad dreams, waking up in the middle of the night, feeling too cold or too hot). Both inattention and SCT were associated with greater daytime dysfunction. Regression analyses demonstrated that hyperactivity predicted sleep quality above and beyond the influence of daytime dysfunction, and inattention and SCT predicted daytime dysfunction above and beyond sleep quality. Further studies are needed to examine the interrelations of nighttime sleep functioning, ADHD/SCT, and daytime dysfunction, as well to elucidate mechanisms contributing to related functional impairments.

  17. Hybrid Discrete Element - Finite Element Simulation for Railway Bridge-Track Interaction

    Science.gov (United States)

    Kaewunruen, S.; Mirza, O.

    2017-10-01

    At the transition zone or sometimes called ‘bridge end’ or ‘bridge approach’, the stiffness difference between plain track and track over bridge often causes aggravated impact loading due to uneven train movement onto the area. The differential track settlement over the transition has been a classical problem in railway networks, especially for the aging rail infrastructures around the world. This problem is also additionally worsened by the fact that the construction practice over the area is difficult, resulting in a poor compaction of formation and subgrade. This paper presents an advanced hybrid simulation using coupled discrete elements and finite elements to investigate dynamic interaction at the transition zone. The goal is to evaluate the dynamic stresses and to better understand the impact dynamics redistribution at the bridge end. An existing bridge ‘Salt Pan Creek Railway Bridge’, located between Revesby and Kingsgrove, has been chosen for detailed investigation. The Salt Pan Bridge currently demonstrates crushing of the ballast causing significant deformation and damage. Thus, it’s imperative to assess the behaviours of the ballast under dynamic loads. This can be achieved by modelling the nonlinear interactions between the steel rail and sleeper, and sleeper to ballast. The continuum solid elements of track components have been modelled using finite element approach, while the granular media (i.e. ballast) have been simulated by discrete element method. The hybrid DE/FE model demonstrates that ballast experiences significant stresses at the contacts between the sleeper and concrete section. These overburden stress exists in the regions below the outer rails, identify fouling and permanent deformation of the ballast.

  18. Responses of stream nitrate and DOC loadings to hydrological forcing and climate change in an upland forest of the northeastern United States

    Science.gov (United States)

    Stephen D. Sebestyen; Elizabeth W. Boyer; James B. Shanley

    2009-01-01

    In coming decades, higher annual temperatures, increased growing season length, and increased dormant season precipitation are expected across the northeastern United States in response to anthropogenic forcing of global climate. We synthesized long-term stream hydrochemical data from the Sleepers River Research Watershed in Vermont, United States, to explore the...

  19. No more moody mornings : Alarm clock anticipates sleepers' emotions

    NARCIS (Netherlands)

    Wensveen, S.; Overbeeke, K.; Van Kasteren, J.

    2002-01-01

    More eloquent alternatives to the harsh tones of the oldfashioned alarm-clock bells abound, including a newsreaders voice summing up last nights disasters, or a tape of your favourite early morning music. Still, getting out of bed has its difficult moments. All this could well change in the near

  20. The Olympic dream.

    Science.gov (United States)

    Donaldson, Caitlyn

    2010-05-01

    Rough sleepers are a very visible sign that even the most 'civilised' of societies have a long way to go. Yet rough sleeping may soon be a thing of the past. Caitlyn Donaldson finds out why you should struggle to find anyone in London without accommodation while enjoying the sporting events of 2012.

  1. Using high-frequency sampling to detect effects of atmospheric pollutants on stream chemistry

    Science.gov (United States)

    Stephen D. Sebestyen; James B. Shanley; Elizabeth W. Boyer

    2009-01-01

    We combined information from long-term (weekly over many years) and short-term (high-frequency during rainfall and snowmelt events) stream water sampling efforts to understand how atmospheric deposition affects stream chemistry. Water samples were collected at the Sleepers River Research Watershed, VT, a temperate upland forest site that receives elevated atmospheric...

  2. Sleep Duration, Mortality, and Heredity-A Prospective Twin Study.

    Science.gov (United States)

    Åkerstedt, Torbjörn; Narusyte, Jurgita; Alexanderson, Kristina; Svedberg, Pia

    2017-10-01

    A number of studies have shown a U-shaped association between sleep duration and mortality. Since sleep duration is partly genetically determined, it seems likely that its association with mortality is also genetically influenced. The purpose of the present study was to investigate the influence on heredity on the association between sleep duration and mortality. We used a cohort of 14267 twins from the Swedish Twin Registry. A Cox proportional hazards regression analysis, adjusted for a number of covariates, confirmed a clear U shape with a hazard ratio (HR) = 1.34 and 95% confidence interval (CI) = 1.15-1.57 for a sleep duration of ≤6.5 hours and HR = 1.18 (CI = 1.07-1.30) for sleep of ≥9.5 hours. Reference value was 7.0 hours. A co-twin analysis of 1942 twins discordant on mortality showed a HR = 2.66 (CI = 1.17-6.04) for long (≥9.5 hours) sleep in monzygotic twins and an HR = 0.66 (CI = 0.20-2.14) for short (sleep. In dizygotic twins, no association was significant. The heritability for mortality was 28% for the whole group, while it was 86% for short sleepers and 42% for long sleepers. Thus, the link with mortality for long sleep appears to be more due to environmental factors than to heredity, while heritability dominates among short sleepers. We found that both long and short sleep were associated with higher total mortality, that the difference in mortality within twin pairs is associated with long sleep, and that short sleep has a higher heritability for mortality, while long sleep is associated with more environmental influences on mortality. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  3. Characterizing Adult Sleep Behavior Over 20 Years-The Population-Based Doetinchem Cohort Study.

    Science.gov (United States)

    Zomers, Margot L; Hulsegge, Gerben; van Oostrom, Sandra H; Proper, Karin I; Verschuren, W M Monique; Picavet, H Susan J

    2017-07-01

    To describe sleep duration patterns of adults over a 20-year period; to compare sociodemographic, lifestyle, and health characteristics across these patterns; and to relate the patterns to sleep quality. The study population consisted of 3695 adults aged 20 to 59 years at baseline. Five measurements of self-reported sleep duration were used to compose seven patterns from 1987 to 2012: persistent short (≤6 hours), moderate (7-8 hours), or long (≥9 hours) sleep duration and several changing patterns (varying and became short, moderate, or long sleepers). Multinomial logistic regression analyses were used to compare characteristics across sleep duration patterns. About 56% of the adults had persistent moderate sleep duration over 20 years. This group had a better sleep quality than the other groups. Of the adults who changed in their sleep duration (40%), 43% became a short sleeper. Sleep duration patterns that deviate from persistent moderate sleep duration were associated with physical inactivity during leisure time (odds ratios [ORs] and 95% confidence intervals [95% CIs] varied between 1.26 [1.04-1.53] and 1.58 [1.06-2.37]) and with poor self-rated health (ORs [95% CIs] varied between 1.50 [1.20-1.87] and 2.15 [1.48-3.12]). Nearly half of the adults did not have persistent moderate sleep duration over a 20-year period and more than one-sixth became short sleeper. This is reason for concern considering the adverse health status associated with short and long sleep duration. Leisure-time physical activity is a potential important target to prevent unfavorable changes in sleep duration over the life course. © Sleep Research Society 2017. Published by Oxford University Press [on behalf of the Sleep Research Society].

  4. Increased plasma orexin-A levels in patients with insomnia disorder are not associated with prepro-orexin or orexin receptor gene polymorphisms.

    Science.gov (United States)

    Tang, Shi; Huang, Weiwei; Lu, Shanshan; Lu, Lili; Li, Guohua; Chen, Xu; Liu, Xiaomin; Lv, Xin; Zhao, Zhangning; Duan, Ruisheng; Du, Yifeng; Tang, Jiyou

    2017-02-01

    Orexins, also known as hypocretins, play a regulatory role in the sleep-wake cycle by activating orexin receptors. Previous animal studies have shown that sleep deprivation can elevate orexinergic peptide levels. However, the relationship between insomnia disorder and orexin-A levels in humans has not been explored. In the current study, we examined plasma orexin-A levels in patients with insomnia disorder and in normal sleepers. We also studied the possible mechanisms underlying changes in orexin-A levels between the study groups; this included investigations of prepro-orexin and orexin receptor gene polymorphisms as well as exploration of other variables. We measured plasma orexin-A levels in 228 patients with insomnia disorder and 282 normal sleepers. The results indicated that the patients with insomnia disorder had significantly higher orexin-A levels than normal sleepers (63.42±37.56 vs. 54.84±23.95pg/ml). A positive relationship was detected between orexin-A level and age in patients with insomnia disorder. Orexin-A levels were elevated in relation to course of insomnia, as well as in relation to increased Insomnia Severity Index score. None of the evaluated prepro-orexin gene single nucleotide polymorphisms were informative between the two study populations. After sequencing all orexin receptor exons, one variation (rs2271933) in the OX1R gene and one variation (rs2653349) in the OX2R gene were found. However, no significant differences were found in either genotypic or allelic frequency distributions between the two study groups. It is suggested that the increased plasma orexin-A levels in patients with insomnia disorder are associated with the course and severity of insomnia, but not with prepro-orexin and orexin receptor gene polymorphisms. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Biomechanical procedure to assess sleep restriction on motor control and learning.

    Science.gov (United States)

    Umemura, G S; Noriega, C L; Soares, D F; Forner-Cordero, A

    2017-07-01

    The analysis of sleep quality during long periods and its impact on motor control and learning performance are crucial aspects for human health. The aim of this study is to analyze effects of chronic sleep restriction on motor performance. It is intended to establish motor control indicators in sleep quality analysis. A wearable actigraphy that records accelerometry, ambient light, and body temperature was used to monitor the sleep habits of 12 healthy subjects for two weeks before performing motor control and learning tests. The day of the motor test, the subjects filled two questionnaires about the quality of sleep (Pittsburgh Sleep Quality Index - PSQI) and sleepiness (Epworth Sleepiness Scale - ESS). Afterwards they performed a coincident timing task that consisted of hitting a virtual target falling on the screen with the hand. An elbow flexion in the horizontal plane had to be performed on the correct time to reach the real target on a table at the same time as the virtual target on the screen. The subjects performed three sets of acquisition and transfer blocks of the coincident timing task. The subjects were clustered in two groups based on the PSQI and ESS scores. Actigraphy and motor control parameters (L5, correct responses, time variance) were compared between groups and experimental sets. The group with better sleep parameters did show a constant performance across blocks of task acquisition while the bad sleeper group improved from the first to the second acquisition block. Despite of this improvement, their performance is not better than the one of the good sleepers group. Although the number of subjects is low and it should be increased, these results indicate that the subjects with better sleep converged rapidly to a high level of performance, while the worse sleepers needed more trials to learn the task and their performance was not superior to the other group.

  6. Circadian activity rhythms for mothers with an infant in ICU

    Directory of Open Access Journals (Sweden)

    Shih-Yu eLee

    2010-12-01

    Full Text Available Circadian rhythms influence sleep and wakefulness. Circadian activity rhythms (CAR are altered in individuals with dementia or seasonal affective disorder. To date, studies exploring CAR and sleep in postpartum women are rare. The purpose of this report is to describe relationships between CAR, sleep disturbance, and fatigue among 72 first-time mothers during their 2nd week postpartum while their newborn remain hospitalized in intensive care unit (ICU. Seventy two mothers were included in this secondary data analysis sample from three separate studies. Participants completed the General Sleep Disturbance Scale (GSDS, Numerical Rating Scale for Fatigue (NRS-F, and a sleep diary. The objective sleep data included total sleep time (TST, wake after sleep onset (WASO, and CAR determined by the circadian quotient (amplitude/mesor averaged from at least 48-hours of wrist actigraphy monitoring. The TST of mothers who self-reported as poor sleepers was 354 minutes (SEM= 21.9, with a mean WASO of 19.5% (SEM= 2.8. The overall sleep quality measured by the GSDS was clinically, significantly disrupted (M= 5.5, SD= 1.2. The mean score for morning fatigue was 5.8 (SD= 2.0, indicating moderate fatigue severity. The CAR was .62 (SEM= .04, indicating poor synchronization. The self-reported good sleepers (GSDS < 3 had better CAR (M= .71, SEM= .02 than poor sleepers (GSDS > 3 (t [70] = 2.0, p< .05. A higher circadian equation was associated with higher TST (r= .83, p<.001, less WASO (r= -.50, p< .001, lower self-reported sleep disturbance scores (r= -.35, p= .01, and less morning fatigue (r= -.26. Findings indicate that mothers with a hospitalized infant have both nocturnal sleep problems and disturbed circadian activity rhythms. Factors responsible for these sleep and rhythm disturbances, the adverse effects on mother’s physical and mental well-being, and mother-infant relationship require further study.

  7. 16 CFR 1632.8 - Glossary of terms.

    Science.gov (United States)

    2010-01-01

    .... The seat slopes, in the sitting position, for added comfort (see fig. 5). (w) Push-back sofa. When... lounge. An upholstered couch chair or a couch with a chair back. It has a permanent back rest, no arms... positions for a chaise lounge effect or a single sleeper. The vertical back support always remains upright...

  8. Selection and testing of ballast stones for underground railway tracks

    African Journals Online (AJOL)

    Ballast is broken pieces of hard rocks such as sandstones, schist, etc. approximately 25- 60 mm size, over which the railway tracks are laid. The function of the ballast is to transfer the applied load over a large surface, provide adequate elasticity, prevent creep and hold the sleepers in position. Also under wet conditions, ...

  9. Physical Activity in Relation to Sleep Among Community-Dwelling Older Adults in China.

    Science.gov (United States)

    Li, Junxin; Yang, Binbin; Varrasse, Miranda; Ji, Xiaopeng; Wu, MaoChun; Li, Manman; Li, Kun

    2018-02-27

    This cross-sectional study was conducted to describe physical activity and sleep in 290 community-dwelling Chinese older adults and to examine the association between physical activity and poor sleep outcomes. Almost half of the sample were poor sleepers. The majority of the sample regularly participated in walking, some household activity and light sports; yet, only a small portion were involved in work-related activity or in strenuous sports. A greater level of overall physical activity [Odds Ratio (OR) =0.79, 95% confidence interval (CI) = (0.73,0.86)], leisure-time exercise [OR=0.77, 95%CI=(0.68,0.85)], and household activity [OR=0.66, 95%CI= (0.56,0.78)] were associated with reduced likelihood of being poor sleepers and other poor sleep outcomes, independent of covariates including age, sex, education, family income, the number of children, drinking, and sleep hygiene. Future larger scale studies that incorporate both objective and subjective measures are needed to further examine the association and to explore the effects of different types of activity on sleep and other well-beings in older adults.

  10. The effect of zolpidem on sleep quality, stress status, and nondipping hypertension.

    Science.gov (United States)

    Huang, Yuli; Mai, Weiyi; Cai, Xiaoyan; Hu, Yunzhao; Song, Yuanbin; Qiu, Ruofeng; Wu, Yanxian; Kuang, Jian

    2012-03-01

    Poor sleep quality and stress status have previously been shown to be closely associated with higher activation of the sympathetic nervous system and to be independent predictors of nondipping hypertension. This study aimed to evaluate the effects of the non-hypotensive sedative zolpidem on sleep quality, stress status, and nondipping hypertension. A total of 103 nondippers were defined as poor or good sleepers by the Pittsburgh Sleep Quality Index. They were randomized to receive zolpidem or placebo treatment for 30 days. Stress status was assessed by the Perceived Stress Scale, and levels of epinephrine and norepinephrine were examined to investigate the underlying mechanisms. Poor sleepers treated with zolpidem for 30 days showed significant improvements in sleep quality and stress levels (Pzolpidem (11 of 22 patients, 50.0%) than in the placebo (2 of 23, 8.7%) (Pzolpidem (Pzolpidem can improve sleep quality and stress status, and can convert nondippers with poor sleep quality into dippers. It may be an option for treating nondipping hypertensive patients with poor sleep quality. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. The Use of Deconstructed Tires as Elastic Elements in Railway Tracks

    Science.gov (United States)

    Sol-Sánchez, Miguel; Moreno-Navarro, Fernando; Rubio-Gámez, Mª Carmen

    2014-01-01

    Elastic elements such as rail pads, under sleeper pads and under ballast mats are railway components that allow for a reduction in track deterioration and vibrations. And they are furthermore commonly used to obtain an optimal vertical stiffness of the infrastructure. However, the use of elastomeric materials can increase construction costs and the consumption of raw materials. Thus, the utilization of used tire layers offers an alternative to reuse an abundant waste reducing the cost of elastic elements. In addition, an innovator technique allows deconstructing tire layers without grinding up the material, reducing production costs at the same time that tire properties are remained. This research is focused on the study of the viability of developing elastic components from used tire layers by evaluating the influence of thickness, the resistance capacity of the elements and their behavior in a ballast box. Results indicate the ability of tire pads to manufacture elastic elements (rail pads, under sleeper pads and under ballast mats) to be used in railway tracks. PMID:28788168

  12. The Use of Deconstructed Tires as Elastic Elements in Railway Tracks

    Directory of Open Access Journals (Sweden)

    Miguel Sol-Sánchez

    2014-08-01

    Full Text Available Elastic elements such as rail pads, under sleeper pads and under ballast mats are railway components that allow for a reduction in track deterioration and vibrations. And they are furthermore commonly used to obtain an optimal vertical stiffness of the infrastructure. However, the use of elastomeric materials can increase construction costs and the consumption of raw materials. Thus, the utilization of used tire layers offers an alternative to reuse an abundant waste reducing the cost of elastic elements. In addition, an innovator technique allows deconstructing tire layers without grinding up the material, reducing production costs at the same time that tire properties are remained. This research is focused on the study of the viability of developing elastic components from used tire layers by evaluating the influence of thickness, the resistance capacity of the elements and their behavior in a ballast box. Results indicate the ability of tire pads to manufacture elastic elements (rail pads, under sleeper pads and under ballast mats to be used in railway tracks.

  13. Analysis of Technology Options to Reduce the Fuel Consumption of Idling Trucks; FINAL

    International Nuclear Information System (INIS)

    Stodolsky, F.; Gaines, L.; Vyas, A.

    2000-01-01

    Long-haul trucks idling overnight consume more than 838 million gallons (20 million barrels) of fuel annually. Idling also emits pollutants. Truck drivers idle their engines primarily to (1) heat or cool the cab and/or sleeper, (2) keep the fuel warm in winter, and (3) keep the engine warm in the winter so that the engine is easier to start. Alternatives to overnight idling could save much of this fuel, reduce emissions, and cut operating costs. Several fuel-efficient alternatives to idling are available to provide heating and cooling: (1) direct-fired heater for cab/sleeper heating, with or without storage cooling; (2) auxiliary power units; and (3) truck stop electrification. Many of these technologies have drawbacks that limit market acceptance. Options that supply electricity are economically viable for trucks that are idled for 1,000-3,000 or more hours a year, while heater units could be used across the board. Payback times for fleets, which would receive quantity discounts on the prices, would be somewhat shorter

  14. Sleep Quality and Academic Performance Among Medical College Students

    Directory of Open Access Journals (Sweden)

    Ameer Kadhim Al-Humairi

    2018-01-01

    Full Text Available Background:Sleep plays a very important role in a human health. Poor sleep quality remains as a frequent feature of student life. Quantity and quality of sleep in addition to average sleep time are strongly linked with students’ learning abilities and academic performance. Subjects and method:The study was a descriptive cross-sectional study conducted to assess sleep quality among medical college students – University of Babylon using Pittsburgh Sleep Quality Index (PSQI. This study was done during April 2016. Results:Mean age of students was (20.63 ± 0.65. Majority was female. According to PSQI(60.4% of students were poor sleeper. Significant association between quality of sleep and academic performance was found in our study, (72.9% of those fail in one or more subjects have poor sleep quality. Conclusion: Poor sleep quality was regarded as an important problem among medical college students. Majority of students (60.4% was poor sleepers. Our study shows significant relation between sleep quality and academic performance among students of Babylon University –College of Medicine.

  15. Multivariate Heteroscedasticity Models for Functional Brain Connectivity

    Directory of Open Access Journals (Sweden)

    Christof Seiler

    2017-12-01

    Full Text Available Functional brain connectivity is the co-occurrence of brain activity in different areas during resting and while doing tasks. The data of interest are multivariate timeseries measured simultaneously across brain parcels using resting-state fMRI (rfMRI. We analyze functional connectivity using two heteroscedasticity models. Our first model is low-dimensional and scales linearly in the number of brain parcels. Our second model scales quadratically. We apply both models to data from the Human Connectome Project (HCP comparing connectivity between short and conventional sleepers. We find stronger functional connectivity in short than conventional sleepers in brain areas consistent with previous findings. This might be due to subjects falling asleep in the scanner. Consequently, we recommend the inclusion of average sleep duration as a covariate to remove unwanted variation in rfMRI studies. A power analysis using the HCP data shows that a sample size of 40 detects 50% of the connectivity at a false discovery rate of 20%. We provide implementations using R and the probabilistic programming language Stan.

  16. Pb and Cd bioaccumulations in the habitat and preys of red-crowned cranes (Grus japonensis) in Zhalong Wetland, Northeastern China.

    Science.gov (United States)

    Luo, Jinming; Yin, Xiongrui; Ya, Yajie; Wang, Yongjie; Zang, Shuying; Zhou, Xia

    2013-12-01

    Pb and Cd concentrations in the habitat and preys of the red-crowned crane (i.e., reed rhizomes and three typical aquatic animal families (Perccottus glehni Dybowski, Carassius auratus Linnaeus, and Viviparidae)) were analyzed to examine the impact of these hazards on red-crowned cranes in northeastern China. Results indicated that Pb and Cd concentrations in the preys of the red-crowned cranes were elevated via food chain. Most of the detected Pb and Cd contents in the sediments were above the natural background level, ranging from 9.85 to 129.72 ppm and 1.23 to 10.63 ppm (dry weight), respectively. Cd geo-accumulation index at all sites were larger than 3, even reached 5.22, suggesting serious pollution in this region. Three common water animal families were detected to contain heavy metals, following the order of increasing concentrations: primary consumers (i.e., Viviparidae and Carassius auratus Linnaeus) cranes showed the highest toxic metal concentrations of Pb (2.09 to 5.81 ppm) and Cd (1.42 to 3.06 ppm) compared with the feces produced by cranes and residual eggshell left by water fowls. Exceptionally high Pb and Cd concentrations in the cranes and their preys were thought to be associated with their habitat.

  17. Utilization of beech

    Energy Technology Data Exchange (ETDEWEB)

    Heckemann, H

    1980-01-01

    The paper reviews (for beech in W. Germany, and, in many cases for competitive hardwoods/softwoods): regional felling statistics/assortment structures; age class structures; profitability/prices; import/export trends; sales trends (for beech timber from Hesse State Forests); beech plywood production; ownership of forests, and specific uses of beech, including as an energy source, in sleepers, and in furniture.

  18. A new record of the non-native fish species Butis koilomatodon (Bleeker 1849 (Teleostei: Eleotridae for southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Riguel Feltrin Contente

    2016-05-01

    Full Text Available This work reports the second record of the Indo-Pacific invasive mud sleeper, Butis koilomatodon, for coastal São Paulo in southeastern Brazil, and represents the southernmost record for this species in the southwestern Atlantic Ocean. The risks of a potential invasion mediated by anthropogenic impacts on the area of occurrence are also discussed.

  19. In-Home Sleep Recordings in Military Veterans With Posttraumatic Stress Disorder Reveal Less REM and Deep Sleep <1 Hz.

    Science.gov (United States)

    Onton, Julie A; Matthews, Scott C; Kang, Dae Y; Coleman, Todd P

    2018-01-01

    Veterans with posttraumatic stress disorder (PTSD) often report suboptimal sleep quality, often described as lack of restfulness for unknown reasons. These experiences are sometimes difficult to objectively quantify in sleep lab assessments. Here, we used a streamlined sleep assessment tool to record in-home 2-channel electroencephalogram (EEG) with concurrent collection of electrodermal activity (EDA) and acceleration. Data from a single forehead channel were transformed into a whole-night spectrogram, and sleep stages were classified using a fully automated algorithm. For this study, 71 control subjects and 60 military-related PTSD subjects were analyzed for percentage of time spent in Light, Hi Deep (1-3 Hz), Lo Deep (spend a smaller percentage of the night in REM ( p spending a larger percentage of the night in Hi Deep ( p < 0.0001) sleep. The percentage of combined Hi+Lo Deep sleep did not differ between groups. All sleepers usually showed EDA peaks during Lo, but not Hi, Deep sleep; however, PTSD sleepers were more likely to lack EDA peaks altogether, which usually coincided with a lack of Lo Deep sleep. Linear regressions with all subjects showed that a decreased percentage of REM sleep in PTSD sleepers was accounted for by age, prazosin, SSRIs and SNRIs ( p < 0.02), while decreased Lo Deep and increased Hi Deep in the PTSD group could not be accounted for by any factor in this study ( p < 0.005). Linear regression models with only the PTSD group showed that decreased REM correlated with self-reported depression, as measured with the Depression, Anxiety, and Stress Scales (DASS; p < 0.00001). DASS anxiety was associated with increased REM time ( p < 0.0001). This study shows altered sleep patterns in sleepers with PTSD that can be partially accounted for by age and medication use; however, differences in deep sleep related to PTSD could not be linked to any known factor. With several medications [prazosin, selective serotonin reuptake inhibitors (SSRIs

  20. Concentrations and content of mercury in bark, wood, and leaves in hardwoods and conifers in four forested sites in the northeastern USA

    Science.gov (United States)

    Yang Yang; Ruth D. Yanai; Charles T. Driscoll; Mario Montesdeoca; Kevin T. Smith

    2018-01-01

    Mercury (Hg) is deposited from the atmosphere to remote areas such as forests, but the amount of Hg in trees is not well known. To determine the importance of Hg in trees, we analyzed foliage, bark and bole wood of eight tree species at four sites in the northeastern USA (Huntington Forest, NY; Sleepers River, VT; Hubbard Brook, NH; Bear Brook, ME). Foliar...

  1. The George Wallace Shooting: News Diffusion and the Sleeper Effect.

    Science.gov (United States)

    Steinfatt, Thomas M.; And Others

    Previous studies conclude that the assassination attempt on George C. Wallace was a news event of high, but not maximum, importance, implying that the majority of respondents in any sample would report first learning of the attack via mass media sources. The authors interviewed 144 persons in Ann Arbor, Michigan, regarding their awareness of the…

  2. The behaviour of mosquitoes in relation to humans under holed bednets: the evidence from experimental huts

    Directory of Open Access Journals (Sweden)

    Seth R Irish

    2014-11-01

    Full Text Available The physical integrity of bednets is a concern of national malaria control programs, as it is a key factor in determining the rate of replacement of bednets. It is largely assumed that increased numbers of holes will result in a loss of protection of sleepers from potentially infective bites. Experimental hut studies are valuable in understanding mosquito behaviour indoors, particularly as it relates to blood feeding and mortality. This review summarises findings from experimental hut studies, focusing on two issues: (i the effect of different numbers or sizes of holes in bednets and (ii feeding behaviour and mortality with holed nets as compared with unholed nets. As might be expected, increasing numbers and area of holes resulted in increased blood feeding by mosquitoes on sleepers. However, the presence of holes did not generally have a large effect on the mortality of mosquitoes. Successfully entering a holed mosquito net does not necessarily mean that mosquitoes spend less time in contact with the net, which could explain the lack in differences in mortality. Further behavioural studies are necessary to understand mosquito behaviour around nets and the importance of holed nets on malaria transmission.

  3. Self-Reported Sleep Duration and Self-Rated Health in Young Adults.

    Science.gov (United States)

    Štefan, Lovro; Juranko, Dora; Prosoli, Rebeka; Barić, Renata; Sporiš, Goran

    2017-07-15

    This study aimed to determine the associations between the self-reported sleep duration and self-rated health in young adults. In this cross-sectional study, participants were 689 young adults (mean age 20 ± 1.35 years, 49.8% female). Sleep duration and self-rated health, as the main outcome of interest, were measured as self-reported. As potential covariates, we included sex, age, smoking status, alcohol consumption, physical activity, sedentary behavior, psychological distress, and body mass index. Approximately 30% of participants slept 7-8 hours, 17.4% were short sleepers (categories 10 hours of sleep). In an unadjusted model, compared with the reference category (7-8 hours of sleep), those who slept health. In an adjusted model, short (sleep (> 10 hours) were both associated with poor self-rated health. Our results suggest that both short ( 10 hours) sleepers have lower odds of having good self-rated health after adjusting for potential covariates. Health professionals should pay more attention to young adults, who have both short and long period of sleep, in order to prevent health problems and potential acute or chronic diseases. © 2017 American Academy of Sleep Medicine

  4. Menopause is associated with self-reported poor sleep quality in women without vasomotor symptoms.

    Science.gov (United States)

    Hung, Hao-Chang; Lu, Feng-Hwa; Ou, Horng-Yih; Wu, Jin-Shang; Yang, Yi-Ching; Chang, Chih-Jen

    2014-08-01

    The aim of this study was to investigate the relationship between menopause and self-reported sleep quality in Chinese women without vasomotor symptoms. Cross-sectional data were collected from a decoded database of the National Cheng Kung University Hospital. Menopause was defined as absence of menses for at least 12 months or a history of hysterectomy and oophorectomy. Self-reported sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). A higher global PSQI score indicates poorer self-reported sleep quality, and a global PSQI score greater than 5 differentiates poor sleepers from good sleepers. Of the 1,088 women recruited, 353 (32.4%) were in postmenopause status. Postmenopausal women had higher mean (SD) global PSQI scores (8.0 [3.3] vs. 6.1 [2.2], P menopause (β = 1.532; 95% CI, 1.135 to 1.949; P menopause (odds ratio, 1.453; 95% CI, 1.030 to 2.051; P menopause and snoring are associated with an increased risk of poor self-reported sleep quality independently of cardiometabolic factors and lifestyle, whereas long sleep duration is associated with a decreased risk of poor self-reported sleep quality.

  5. Cognitive Behavioral Social Rhythm Therapy (CBSRT) for Sleep and Mood Disturbances in Veterans with PTSD

    Science.gov (United States)

    2012-09-01

    Patricia.Haynes3@va.gov Fax: (520) 626-6050 E-mail: thaynes@email.arizona.edu Home Address: Citizenship : United States 2828 W. Calle...of the Ambivalent Sleeper [Board Review Question]. Journal of Clinical Sleep Medicine, 15, 511-512. Haynes, P. L. (2009). Is CBT-I effective for...Support Networks in Asymptomatic Individuals with a History of Depression Versus Never-Depressed Individuals. Personal Life Events: Birth of Child

  6. In-Home Sleep Recordings in Military Veterans With Posttraumatic Stress Disorder Reveal Less REM and Deep Sleep <1 Hz

    Science.gov (United States)

    Onton, Julie A.; Matthews, Scott C.; Kang, Dae Y.; Coleman, Todd P.

    2018-01-01

    Veterans with posttraumatic stress disorder (PTSD) often report suboptimal sleep quality, often described as lack of restfulness for unknown reasons. These experiences are sometimes difficult to objectively quantify in sleep lab assessments. Here, we used a streamlined sleep assessment tool to record in-home 2-channel electroencephalogram (EEG) with concurrent collection of electrodermal activity (EDA) and acceleration. Data from a single forehead channel were transformed into a whole-night spectrogram, and sleep stages were classified using a fully automated algorithm. For this study, 71 control subjects and 60 military-related PTSD subjects were analyzed for percentage of time spent in Light, Hi Deep (1–3 Hz), Lo Deep (Deep (p = 0.001) sleep, while spending a larger percentage of the night in Hi Deep (p Deep sleep did not differ between groups. All sleepers usually showed EDA peaks during Lo, but not Hi, Deep sleep; however, PTSD sleepers were more likely to lack EDA peaks altogether, which usually coincided with a lack of Lo Deep sleep. Linear regressions with all subjects showed that a decreased percentage of REM sleep in PTSD sleepers was accounted for by age, prazosin, SSRIs and SNRIs (p Deep and increased Hi Deep in the PTSD group could not be accounted for by any factor in this study (p deep sleep related to PTSD could not be linked to any known factor. With several medications [prazosin, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs); p < 0.03], as well as SSRIs were associated with less sleep efficiency (b = -3.3 ± 0.95; p = 0.0005) and more sleep fragmentation (b = -1.7 ± 0.51; p = 0.0009). Anti-psychotics were associated with less sleep efficiency (b = -4.9 ± 1.4; p = 0.0004). Sleep efficiency was negatively impacted by SSRIs, antipsychotic medications, and depression (p < 0.008). Increased sleep fragmentation was associated with SSRIs, SNRIs, and anxiety (p < 0.009), while prazosin and

  7. Tactile arousal threshold of sleeping king penguins in a breeding colony.

    Science.gov (United States)

    Dewasmes, G; Telliez, F

    2000-09-01

    The tactile arousal threshold of sleeping birds has not been investigated to date. In this study, the characteristics of this threshold were assessed by stimulating either the upper back or a foot of two groups (one cutaneous site per group) of 60 sleeping king penguins (Aptenodytes patagonica) in the breeding colony of Baie du Marin (Crozet Archipelago). Increasing weights were put onto one of the feet or the upper back of individuals that had been sleeping for more than 5 min until they showed behavioural signs of arousal (head raising). The weight applied to the upper back that was needed to awaken a sleeper (837 +/- 73 g) was 20 times greater than that applied to a foot (38 +/- 6 g). In terms of pressure, the difference remained five times higher for the back (209 +/- 18 g/cm(2)) than the foot (40 g +/- 7 g/cm(2)). Because the king penguin incubates its single egg and rears its young chick on its feet, the low threshold measured at this level could be viewed as an adaptation against progeny predation. Sleepers are frequently bumped by conspecifics walking through the colony. The increased arousal threshold associated with tactile stimulation of the back may help to preserve sleep continuity under these conditions.

  8. Does self-reported sleep quality predict poor cognitive performance among elderly living in elderly homes?

    Science.gov (United States)

    Amer, Motassem S; Hamza, Sarah A; El Akkad, Rania M; Abdel Galeel, Yamen I I

    2013-01-01

    Sleep complaints are common among elderly, especially institutionalized elderly, as they experience poorer sleep quality and higher use of sedative hypnotics, when compared to community-dwelling elderly. Recent findings suggest that there may be a relationship between poor quality of sleep and cognitive deficits. This study aimed at studying the relation between sleep quality and cognitive performance in older adults living in elderly homes. 100 elderly living in an elderly home in El Mansoura, Egypt, were recruited in this study, 50 cases with subjective poor quality of sleep and 50 controls with subjective good quality of sleep as assessed by Pittsburgh sleep quality index (PSQI). Each participant went through comprehensive geriatric assessment (CGA), including geriatric depression scale (GDS), assessment of cognitive function by mini mental state examination (MMSE). 52% of poor sleepers showed impaired MMSE, while only 24% of good sleepers had impaired MMSE. Both orientation and (attention and calculation) were more affected (P = 0.027 and 0.035, respectively). Linear correlation coefficient between PSQI and different variables revealed significant negative correlation with total MMSE score, attention and calculation. Poor quality of sleep is related to cognitive impairment among elderly living in elderly homes and this problem should be taken in consideration among this group of elders.

  9. Association between stress-related sleep reactivity and cognitive processes in insomnia disorder and insomnia subgroups: preliminary results.

    Science.gov (United States)

    Palagini, Laura; Faraguna, Ugo; Mauri, Mauro; Gronchi, Alessia; Morin, Charles M; Riemann, Dieter

    2016-03-01

    Stress-related sleep reactivity, sleep-related cognitions, and psychological factors play an important role in insomnia. The aim was to investigate their possible association in Insomnia Disorder, insomnia subgroups, and healthy subjects. The cross-sectional study consisted of 93 subjects who met diagnostic criteria for Insomnia Disorder according to Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) and of 30 healthy subjects. Survey instruments included the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Ford Insomnia Response to Stress Test (FIRST), Dysfunctional Beliefs about Sleep scale (DBAS), Beck Depression Inventory (BDI), and Zung Self-Rating Anxiety Scale (SAS). Descriptive statistics, Pearson correlations, χ(2)-test, and multiple linear regression were performed. FIRST and SAS best determined the insomnia subjects vs good sleepers (FIRST χ(2) = 109.6, p insomnia, stress-related sleep reactivity, and psychological factors, such as anxiety symptoms, may distinguish insomnia subjects from good sleepers; (2) sleep reactivity and sleep-related cognitions seem interrelated, unhelpful beliefs may affect the stress reactivity; (3) psychological factors may influence sleep quality and the severity of insomnia; (4) these important sleep-related variables may have similar associations in insomnia subgroups; they may constitute the core factors for insomnia development and maintenance. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Impact of the rail-pad multi-discrete model upon the prediction of the rail response

    Science.gov (United States)

    Mazilu, T.; Leu, M.

    2017-08-01

    Wheel/rail vibration has many technical effects such as wear of the rolling surfaces, rolling noise, settlement of the ballast and subgrade etc. This vibration is depending on the rail pad characteristic and subsequently, it is important to have an accurate overview on the relation between the rail pad characteristic and the level of the wheel/rail vibration. To this end, much theoretical and experimental research has been developed in the past, and for the theoretical approach the track model, in general, and, particularly, the rail pad model is of crucial importance. Usually, the rail pad model is discrete model one, neglecting the length of the rail pad. This fact is questionable because the sleepers span is only 4 times the rail pad length. Using the rail pad discrete model, the rail response is overestimated when the frequency of the excitation equals the pinned-pinned resonance frequency. In this paper, a multi-discrete model for the rail pad, consisting in many Kelvin-Voigt parallel systems, is inserted into an analytical model of the track. The track model is reduced to a rail taken as infinite Timoshenko beam, discretely supported via rail pad, sleeper and ballast. The influence of the number of Kelvin-Voigt systems of the rail pad model on the rail response is analysed.

  11. The relationship between brain morphology and polysomnography in healthy good sleepers.

    Directory of Open Access Journals (Sweden)

    Matthias A Reinhard

    Full Text Available Normal sleep continuity and architecture show remarkable inter-individual variability. Previous studies suggest that brain morphology may explain inter-individual differences in sleep variables.Thirty-eight healthy subjects spent two consecutive nights at the sleep laboratory with polysomnographic monitoring. Furthermore, high-resolution T1-weighted MRI datasets were acquired in all participants. EEG sleep recordings were analyzed using standard sleep staging criteria and power spectral analysis. Using the FreeSurfer software for automated segmentation, 174 variables were determined representing the volume and thickness of cortical segments and the volume of subcortical brain areas. Regression analyses were performed to examine the relationship with polysomnographic and spectral EEG power variables.The analysis did not provide any support for the a-priori formulated hypotheses of an association between brain morphology and polysomnographic variables. Exploratory analyses revealed that the thickness of the left caudal anterior cingulate cortex was positively associated with EEG beta2 power (24-32 Hz during REM sleep. The volume of the left postcentral gyrus was positively associated with periodic leg movements during sleep (PLMS.The function of the anterior cingulate cortex as well as EEG beta power during REM sleep have been related to dreaming and sleep-related memory consolidation, which may explain the observed correlation. Increased volumes of the postcentral gyrus may be the result of increased sensory input associated with PLMS. However, due to the exploratory nature of the corresponding analyses, these results have to be replicated before drawing firm conclusions.

  12. [The effects of noise on sleep and their possible repercussions on health].

    Science.gov (United States)

    Muzet, Alain

    2006-11-01

    Sleep is a physiological recuperative state susceptible to be disturbed or reduced in length under external stimuli, such as noise, one of the most frequent ambient factors. Sleep disturbance is often accompanied by a reduced quality of the following waking period. The health effects of prolonged exposure to noise concern life quality, as expressed subjectively by the sleeper, as well as probable effect on cardiovascular function through a non specific aggression related to stress.

  13. A new record of the non-native fish species Butis koilomatodon (Bleeker 1849 (Teleostei: Eleotridae for southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Riguel Feltrin Contente

    2016-05-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2016v29n2p113 This work reports the second record of the Indo-Pacific invasive mud sleeper, Butis koilomatodon, for coastal São Paulo in southeastern Brazil, and represents the southernmost record for this species in the southwestern Atlantic Ocean. The risks of a potential invasion mediated by anthropogenic impacts on the area of occurrence are also discussed.

  14. Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects.

    Science.gov (United States)

    Gerhart, James I; Burns, John W; Post, Kristina M; Smith, David A; Porter, Laura S; Burgess, Helen J; Schuster, Erik; Buvanendran, Asokumar; Fras, Anne Marie; Keefe, Francis J

    2017-06-01

    Poor sleep quality among people with chronic low back pain appears to be related to worse pain, affect, poor physical function, and pain catastrophizing. The causal direction between poor sleep and pain remains an open question, however, as does whether sleep quality exerts effects on low back pain differently across the course of the day. This daily diary study examined lagged temporal associations between prior night sleep quality and subsequent day pain, affect, physical function and pain catastrophizing, the reverse lagged temporal associations between prior day pain-related factors and subsequent night sleep quality, and whether the time of day during which an assessment was made moderated these temporal associations. Chronic low back pain patients (n = 105) completed structured electronic diary assessments five times per day for 14 days. Items included patient ratings of their pain, affect, physical function, and pain catastrophizing. Collapsed across all observations, poorer sleep quality was significantly related to higher pain ratings, higher negative affect, lower positive affect, poorer physical function, and higher pain catastrophizing. Lagged analyses averaged across the day revealed that poorer prior night sleep quality significantly predicted greater next day patient ratings of pain, and poorer physical function and higher pain catastrophizing. Prior poorer night sleep quality significantly predicted greater reports of pain, and poorer physical function, and higher pain catastrophizing, especially during the early part of the day. Sleep quality × time of day interactions showed that poor sleepers reported high pain, and negative mood and low function uniformly across the day, whereas good sleepers reported relatively good mornings, but showed pain, affect and function levels comparable to poor sleepers by the end of the day. Analyses of the reverse causal pathway were mostly nonsignificant. Sleep quality appears related not only to pain intensity

  15. Comparison of total mercury and methylmercury cycling at five sites using the small watershed approach

    Energy Technology Data Exchange (ETDEWEB)

    Shanley, James B. [US Geological Survey, PO Box 628, Montpelier, VT 05601 (United States)], E-mail: jshanley@usgs.gov; Alisa Mast, M. [US Geological Survey, MS 415 Denver Federal Center, Denver, CO 80225 (United States)], E-mail: mamast@usgs.gov; Campbell, Donald H. [US Geological Survey, MS 415 Denver Federal Center, Denver, CO 80225 (United States)], E-mail: dhcampbe@usgs.gov; Aiken, George R. [US Geological Survey, 3215 Marine Street, Suite E-127, Boulder, CO 80303 (United States)], E-mail: graiken@usgs.gov; Krabbenhoft, David P. [US Geological Survey, 8505 Research Way, Middleton, WI 53562 (United States)], E-mail: dpkrabbe@usgs.gov; Hunt, Randall J. [US Geological Survey, 8505 Research Way, Middleton, WI 53562 (United States)], E-mail: rjhunt@usgs.gov; Walker, John F. [US Geological Survey, 8505 Research Way, Middleton, WI 53562 (United States)], E-mail: jfwalker@usgs.gov; Schuster, Paul F. [US Geological Survey, 3215 Marine Street, Suite E-127, Boulder, CO 80303 (United States)], E-mail: pschuste@usgs.gov; Chalmers, Ann [US Geological Survey, PO Box 628, Montpelier, VT 05601 (United States)], E-mail: chalmers@usgs.gov; Aulenbach, Brent T. [US Geological Survey, 3039 Amwiler Road, Suite 130, Atlanta, GA 30360 (United States)], E-mail: btaulenb@usgs.gov; Peters, Norman E. [US Geological Survey, 3039 Amwiler Road, Suite 130, Atlanta, GA 30360 (United States)], E-mail: nepeters@usgs.gov; Marvin-DiPasquale, Mark [US Geological Survey, 345 Middlefield Rd., MS 480, Menlo Park, CA 94025 (United States)], E-mail: mmarvin@usgs.gov; Clow, David W. [US Geological Survey, MS 415 Denver Federal Center, Denver, CO 80225 (United States)], E-mail: dwclow@usgs.gov; Shafer, Martin M. [Environmental Chemistry and Technology and Wisconsin State Laboratory of Hygiene, University of Wisconsin, Madison, WI 53706 (United States)], E-mail: mmshafer@wisc.edu

    2008-07-15

    The small watershed approach is well-suited but underutilized in mercury research. We applied the small watershed approach to investigate total mercury (THg) and methylmercury (MeHg) dynamics in streamwater at the five diverse forested headwater catchments of the US Geological Survey Water, Energy, and Biogeochemical Budgets (WEBB) program. At all sites, baseflow THg was generally less than 1 ng L{sup -1} and MeHg was less than 0.2 ng L{sup -1}. THg and MeHg concentrations increased with streamflow, so export was primarily episodic. At three sites, THg and MeHg concentration and export were dominated by the particulate fraction in association with POC at high flows, with maximum THg (MeHg) concentrations of 94 (2.56) ng L{sup -1} at Sleepers River, Vermont; 112 (0.75) ng L{sup -1} at Rio Icacos, Puerto Rico; and 55 (0.80) ng L{sup -1} at Panola Mt., Georgia. Filtered (<0.7 {mu}m) THg increased more modestly with flow in association with the hydrophobic acid fraction (HPOA) of DOC, with maximum filtered THg concentrations near 5 ng L{sup -1} at both Sleepers and Icacos. At Andrews Creek, Colorado, THg export was also episodic but was dominated by filtered THg, as POC concentrations were low. MeHg typically tracked THg so that each site had a fairly constant MeHg/THg ratio, which ranged from near zero at Andrews to 15% at the low-relief, groundwater-dominated Allequash Creek, Wisconsin. Allequash was the only site with filtered MeHg consistently above detection, and the filtered fraction dominated both THg and MeHg. Relative to inputs in wet deposition, watershed retention of THg (minus any subsequent volatilization) was 96.6% at Allequash, 60% at Sleepers, and 83% at Andrews. Icacos had a net export of THg, possibly due to historic gold mining or frequent disturbance from landslides. Quantification and interpretation of Hg dynamics was facilitated by the small watershed approach with emphasis on event sampling. - High-flow sampling reveals strong contrasts in total

  16. Exploration of changes in the brain response to sleep-related pictures after cognitive–behavioral therapy for psychophysiological insomnia

    OpenAIRE

    Kim, Seog Ju; Lee, Yu Jin; Kim, Nambeom; Kim, Soohyun; Choi, Jae-Won; Park, Juhyun; Gwak, Ah Reum; Kang, Chang-Ki; Kang, Seung-Gul; Jeong, Do-Un

    2017-01-01

    Psychophysiological insomnia (PI) includes arousal to sleep-related stimuli (SS), which can be treated by cognitive behavioral therapy for insomnia (CBT-I). The present study was an exploratory, prospective intervention study that aimed to explore brain response to visual SS in PI before and after CBT-I. Blood oxygen level dependent (BOLD) signal differences in response to SS and neutral stimuli (NS) were compared between 14 drug-free PI patients and 18 good sleepers (GS) using functional mag...

  17. The Use of Deconstructed Tires as Elastic Elements in Railway Tracks

    OpenAIRE

    Sol-S?nchez, Miguel; Moreno-Navarro, Fernando; Rubio-G?mez, M? Carmen

    2014-01-01

    Elastic elements such as rail pads, under sleeper pads and under ballast mats are railway components that allow for a reduction in track deterioration and vibrations. And they are furthermore commonly used to obtain an optimal vertical stiffness of the infrastructure. However, the use of elastomeric materials can increase construction costs and the consumption of raw materials. Thus, the utilization of used tire layers offers an alternative to reuse an abundant waste reducing the cost of ela...

  18. Sleep Strategies of Night-Shift Nurses on Days Off: Which Ones are Most Adaptive?

    Science.gov (United States)

    Petrov, Megan E; Clark, C Brendan; Molzof, Hylton E; Johnson, Russell L; Cropsey, Karen L; Gamble, Karen L

    2014-01-01

    To determine the off-shift sleep strategies of bi-ethnic night-shift nurses, the relationship between these sleep strategies and adaptation to shift work, and identify the participant-level characteristics associated with a given sleep strategy. African-American and non-Hispanic White female, night-shift nurses from an academic hospital were recruited to complete a survey on sleep-wake patterns (n = 213). Participants completed the standard shiftwork index and the biological clocks questionnaire to determine sleep strategies and adaptation to night-shift work. In addition, chronotype was determined quantitatively with a modified version of the Munich ChronoType Questionnaire. Most participants worked ~3 consecutive 12-h night-shifts followed by several days off. Five sleep strategies used on days off were identified: (a) night stay, (b) nap proxy, (c) switch sleeper, (d) no sleep, and (e) incomplete switcher. Nap proxy and no sleep types were associated with poorer adaptation to night-shift work. The switch sleeper and incomplete switcher types were identified as more adaptive strategies that were associated with less sleep disturbance, a later chronotype, and less cardiovascular problems. Behavioral sleep strategies are related to adaptation to a typical night-shift schedule among hospital nurses. Nurses are crucial to the safety and well-being of their patients. Therefore, adoption of more adaptive sleep strategies may reduce sleep/wake dysregulation in this population, and improve cardiovascular outcomes.

  19. PRESERVAÇÃO DE MADEIRAS NO BRASIL: HISTÓRICO, CENÁRIO ATUAL E TENDÊNCIAS

    Directory of Open Access Journals (Sweden)

    Jackson Marcelo Vidal

    2015-01-01

    Full Text Available The objective of this paper was to show a comprehensive literature review about wood preservation in Brazil, since the earliest years until 2011. Brazil is rich in natural resources and wood has always occurred in abundance. With the industrial growing, there was the necessity of using wood with low natural durability but with chemical preservative treatment. Wood chemical treatment began in late XIX century, mainly to attend the big demand of sleepers to railroads. Only during the 60’s, wood preservation gained market with the increase of scientific researches, elaboration of technical standards and building industrial plants for wood preservation. From this point on, few advances have been reached. In 2011, Eucalyptus and Pinus, were the main species used in wood preservation plants that adopts the vacuum-pressure process. In small production scale, diffusion process is adopted. Copper chromium arsenate (CCA and Copper chromium borate (CCB are the most preservatives utilised with some creosote utilisation. The treatedwood production is concentrated in fence posts, poles and sleepers. As a trend, the wood preservation must reach new markets, such as building constructions, wood packages and crossarms, and also to intensify the traditional uses. Although there are a lot of researches about chemicals for wood preservation, CCA must keep by the years, once alternative products do not present the same efficacy or clear effects about human health and environment.

  20. Insomnia and Relationship with Anxiety in University Students: A Cross-Sectional Designed Study.

    Science.gov (United States)

    Choueiry, Nour; Salamoun, Tracy; Jabbour, Hicham; El Osta, Nada; Hajj, Aline; Rabbaa Khabbaz, Lydia

    2016-01-01

    Sleep disorders (SDs) are now recognized as a public health concern with considerable psychiatric and societal consequences specifically on the academic life of students. The aims of this study were to assess SDs in a group of university students in Lebanon and to examine the relationship between SDs and anxiety. An observational cross-sectional study was conducted at Saint-Joseph University, Lebanon, during the academic year 2013-2014. Four questionnaires were face-to-face administered to 462 students after obtaining their written consent: Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and Generalized Anxiety Disorder 7-item scale (GAD-7). The prevalence of clinically significant insomnia was 10.6% (95% CI: 7.8-13.4%), more frequent in first year students. ISI mean score was 10.06 (SD = 3.76). 37.1% of the participants were poor sleepers. Excessive daytime sleepiness (EDS) and poor sleep were significantly more frequent among participants with clinical insomnia (p = 0.031 and 0.001 respectively). Clinically significant anxiety was more frequent in students suffering from clinical insomnia (p = 0.006) and in poor sleepers (p = 0.003). 50.8% of the participants with clinically significant anxiety presented EDS versus 30.9% of those with no clinically significant anxiety (panxiety reminds us of the importance of treating anxiety as soon as detected and not simply targeting the reduction of sleep problems.

  1. The association between prenatal sleep quality and obstetric outcome.

    Science.gov (United States)

    Hung, Hsuan-Man; Ko, Shu-Hua; Chen, Chung-Hey

    2014-09-01

    Pregnancy-associated sleep disorder is a new category on the latest version of the International Classification of Sleep Disorders. It is a significant problem for pregnant women. The present follow-up study assesses the association between sleep quality during the second and third trimesters of pregnancy and obstetric-neonatal outcomes. A prospective follow-up study design was used. Follow-up examination of the obstetric birth records in the immediate postpartum period were carried out on 128 second-trimester and 120 third-trimester women and their newborns in two hospitals in Taiwan. Poor sleep quality was identified using the Pittsburgh Sleep Quality Index. Data were collected from October 2007 to June 2008. The prevalence of poor sleepers (Pittsburgh Sleep Quality Index score > 5) was 58% for second-trimester participants and 66% for third-trimester participants; participants who were unemployed reported a significantly higher prevalence of poor sleep quality than those who were employed. Subsequent review of the participant's obstetric birth records revealed that third-trimester poor sleepers were more likely to have had a vacuum-assisted delivery. This study identified poor sleep quality during the third trimester as a novel risk factor for vacuum-assisted delivery. We suggest that prenatal healthcare providers focus greater attention to the sleep disturbance condition of pregnant women and provide proactive sleep counseling to facilitate pregnant women's adjustment to the new psychosocial and physiological demands of motherhood.

  2. Survey on a sleep habits for university and high school students.

    OpenAIRE

    林, 光緒; 堀, 忠雄

    1988-01-01

    A survey was performed on 466 high school students and 403 university students. 86% of high school students and 89% of university students estimated their customary sleep time to be 6-8 hours. Although there was no significant difference between high school students and university students with awake time, bed time was later for university students than high school students. So that sleep time was shorter for university students. Also there was more regular sleepers for high school students a...

  3. Anaesthesia in Dental Medicine with Local Infiltrative Anaesthetic Technique Versus Diploe Anaesthesia Delivery Systems: Efficacy and Behaviour, an Experimental Study

    OpenAIRE

    Manuel Marques-Ferreira; Eunice Carrilho; Siri Paulo; Teresa Carrilho; José Pedro Figueiredo; Ricardo Macedo

    2017-01-01

    Introduction: This study aimed to compare the analgesic efficacy and the influence of local infiltrative anesthesia techniques, with diploe anesthesia, on the cardiac rhythm Material and Methods: We selected 32 healthy volunteers who were given both anaesthetic techniques on tooth 1.4 (0.45 mL of lidocaine with adrenaline, 1:80 000). In the first phase, the volunteers underwent periapical infiltrative anaesthesia. In the second phase, diploe anaesthesia was performed with a QuickSleeper® d...

  4. General Recommendations on Fatigue Risk Management for the Canadian Forces

    Science.gov (United States)

    2010-04-01

    package. Tea 8 - 90 mg/cup Caffeine depends on how strong is the brew. Cola drinks 35 mg/250 ml Often contains much sugar. Cocoa and chocolates 10...70 mg/cup Caffeine content depends on how strong the brew is, and other chemical content in the product. Chocolate bars 20 - 60 mg/200g Contains...hygiene practices of good and poor sleepers in the United State: an internet based study. Behavior Therapy . 40(1):1-9. Hayashi M., Watanabe M

  5. Сравнительная характеристика показателей внутрикостной анестезии с использованием автоматизированного устройства QuickSleeper при разной скорости введения анестетика

    OpenAIRE

    Серикова, О.; Полушакова, Н.; Трифонов, Б.

    2011-01-01

    В статье представлены результаты комплексного клинико-лабораторного исследования эффективности и безопасности применения электронной системы QuickSleeper для внутрикост-ной анестезии при реставрации фронтальной группы зубов верхней челюсти. Авторами проведено клиническое обследование больных, анализ рентгенографических данных, болевой чувствительности. Предметом специальных исследований при использовании устройства QuickSleeper было определение основных параметров гемодинамики и уровня глюкоз...

  6. Peruvians’ sleep duration: analysis of a population-based survey on adolescents and adults

    Directory of Open Access Journals (Sweden)

    Rodrigo M. Carrillo-Larco

    2014-04-01

    Full Text Available Background. Sleep duration, either short or long, has been associated with diseases such as obesity, type-2 diabetes and cardiovascular diseases. Characterizing the prevalence and patterns of sleep duration at the population-level, especially in resource-constrained settings, will provide informative evidence on a potentially modifiable risk factor. The aim of this study was to explore the patterns of sleep duration in the Peruvian adult and adolescent population, together with its socio-demographic profile.Material and Methods. A total of 12,424 subjects, mean age 35.8 years (SD ±17.7, 50.6% males, were included in the analysis. This is a cross-sectional study, secondary analysis of the Use of Time National Survey conducted in 2010. We used weighted means and proportions to describe sleep duration according to socio-demographic variables (area and region; sex; age; education attainment; asset index; martial and job status. We used Poisson regressions, taking into account the multistage sampling design of the survey, to calculate crude and adjusted prevalence ratios (PR and 95% confidence intervals (95% CI. Main outcomes were short- (<6 h and long-sleep duration (≥ 9 h.Results. On average, Peruvians slept 7.7 h (95% CI [7.4–8.0] on weekdays and 8.0 h (95% CI [7.8–8.1] during weekends. The proportions of short- and long-sleep, during weekdays, were 4.3% (95% CI [2.9%–6.3%] and 22.4% (95% CI [14.9%–32.1%], respectively. Regarding urban and rural areas, a much higher proportion of short-sleep was observed in the former (92.0% vs. 8.0%; both for weekdays and weekends. On the multivariable analysis, compared to regular-sleepers (≥ 6 to <9 h, short-sleepers were twice more likely to be older and to have higher educational status, and 50% more likely to be currently employed. Similarly, relative to regular-sleep, long-sleepers were more likely to have a lower socioeconomic status as per educational attainment.Conclusions. In this

  7. Relationships between dissolved organic matter and discharge: New insights from in-situ measurements in a northern forested watershed

    Science.gov (United States)

    Pellerin, B. A.; Shanley, J. B.; Saraceno, J.; Aiken, G.; Sebestyen, S. D.; Bergamaschi, B. A.

    2012-12-01

    Quantifying the fundamental linkages between hydrology and dissolved organic matter (DOM) dynamics in streams and rivers is critical for understanding carbon loads, ecosystem food webs and metal transport. Accurately assessing this relationship is difficult, however, given that rapid changes in water flow paths and associated DOM sources are often not captured by traditional discrete sampling intervals of weeks to months. We explored DOM - discharge relationships at Sleepers River below a 40.5 hectare USGS research watershed in northern Vermont by making 30 minute chromophoric DOM fluorescence (FDOM) measurements in-situ since October 2008 along with periodic discrete sampling for dissolved organic carbon. There is a tight coupling between the timing of increases in FDOM and discharge at Sleepers during events, but the ratio of FDOM to discharge exhibited considerable variability across seasons and events, as did FDOM-discharge hysteresis (FDOM variously peaked 1-4 hours after streamflow). Discrete DOM quality indicators (spectral slope, fluorescence index, SUVA) indicate DOM was predominantly terrestrial at all but the lowest flows, highlighting the important role of DOM-rich terrestrial flow paths as the primary source of stream DOM. Our results suggest that changes in flow paths are likely to be the primary drivers of future changes in DOM transport from this site rather than changes in DOM quality. Overcoming significant challenges inherent in continuous sensor deployments in watersheds (e.g. ice cover, suspended particles, remote communication and power) will allow for new insights into watershed biogeochemistry.

  8. Association of sleep duration with rheumatoid arthritis in Korean adults: analysis of seven years of aggregated data from the Korea National Health and Nutrition Examination Survey (KNHANES).

    Science.gov (United States)

    Kim, Jae-Hyun; Park, Eun-Cheol; Lee, Kwang Soo; Lee, Yunhwan; Shim, Sungkeun; Kim, Jinhee; Chon, Doukyoung; Lee, Sang-Gue

    2016-12-13

    To investigate the association between rheumatoid arthritis (RA) and self-reported sleep duration. The present study analysed 7 years of aggregated cross-sectional data (2007-2013) from the Korea National Health and Nutrition Examination Surveys (KNHANES). A total of 37 979 individuals were selected for the analyses. RA. Sleep duration. After adjusting for confounding factors, the odds of short-duration sleepers (≤6 hours/day) and long-duration sleepers (≥9 hours/day) for RA were 1.23-fold (95% CI 1.101 to 1.51) and 1.27-fold (95% CI 0.85 to 1.88) higher, respectively, than those for persons with sleep duration of 7-8 hours/day. A subgroup analysis according to the extent of pain in RA revealed that the strong relationship between RA and sleep disturbances was observed in those with high pain from RA (OR: 1.28 CI 1.04 to 1.58). Individuals with RA may be at a higher risk for sleep disturbances compared with individuals without RA. Therefore, the provision of comprehensive care for patients with RA by healthcare professionals should include assessments of sleep duration and patients with RA should be encouraged to report sleep problems. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  9. Arousal from sleep mechanisms in infants.

    Science.gov (United States)

    Franco, Patricia; Kato, Ineko; Richardson, Heidi L; Yang, Joel S C; Montemitro, Enza; Horne, Rosemary S C

    2010-08-01

    Arousals from sleep allow sleep to continue in the face of stimuli that normally elicit responses during wakefulness and also permit awakening. Such an adaptive mechanism implies that any malfunction may have clinical importance. Inadequate control of arousal in infants and children is associated with a variety of sleep-related problems. An excessive propensity to arouse from sleep favors the development of repeated sleep disruptions and insomnia, with impairment of daytime alertness and performance. A lack of an adequate arousal response to a noxious nocturnal stimulus reduces an infant's chances of autoresuscitation, and thus survival, increasing the risk for Sudden Infant Death Syndrome (SIDS). The study of arousability is complicated by many factors including the definition of an arousal; the scoring methodology; the techniques used (spontaneous arousability versus arousal responses to endogenous or exogenous stimuli); and the confounding factors that complicate the determination of arousal thresholds by changing the sleeper's responses to a given stimulus such as prenatal drug, alcohol, or cigarette use. Infant age and previous sleep deprivation also modify thresholds. Other confounding factors include time of night, sleep stages, the sleeper's body position, and sleeping conditions. In this paper, we will review these different aspects for the study of arousals in infants and also report the importance of these studies for the understanding of the pathophysiology of some clinical conditions, particularly SIDS. Copyright 2010 Elsevier B.V. All rights reserved.

  10. [Excessive Daytime Sleepiness, Poor Quality Sleep, and Low Academic Performance in Medical Students].

    Science.gov (United States)

    Machado-Duque, Manuel Enrique; Echeverri Chabur, Jorge Enrique; Machado-Alba, Jorge Enrique

    2015-01-01

    Quality of sleep and excessive daytime sleepiness (EDS) affect cognitive ability and performance of medical students. This study attempts to determine the prevalence of EDS, sleep quality, and assess their association with poor academic performance in this population. A descriptive, observational study was conducted on a random sample of 217 medical students from the Universidad Tecnológica de Pereira, who completed the Pittsburgh Sleep Quality Index (PSQI) questionnaire and the Epworth sleepiness scale. Sociodemographic, clinic and academic variables were also measured. Multivariate analyses for poor academic performance were performed. The included students had a mean age of 21.7±3.3 years, of whom 59.4% were men. Almost half (49.8%) had EDS criteria, and 79.3% were poor sleepers (PSQI ≥ 5), while 43.3% had poor academic performance during the last semester. The bivariate analysis showed that having used tobacco or alcohol until intoxicated, fairly bad subjective sleep quality, sleep efficiency < 65%, and being a poor sleeper were associated with increased risk of low performance. Sleep efficiency < 65% was statistically associated with poor academic performance (P=.024; OR = 4.23; 95% CI, 1.12-15.42) in the multivariate analysis. A poor sleep quality determined by low efficiency was related to poor academic achievement at the end of semester in medical students. Copyright © 2015 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  11. Interaction between hippocampal and striatal systems predicts subsequent consolidation of motor sequence memory.

    Directory of Open Access Journals (Sweden)

    Geneviève Albouy

    Full Text Available The development of fast and reproducible motor behavior is a crucial human capacity. The aim of the present study was to address the relationship between the implementation of consistent behavior during initial training on a sequential motor task (the Finger Tapping Task and subsequent sleep-dependent motor sequence memory consolidation, using functional magnetic resonance imaging (fMRI and total sleep deprivation protocol. Our behavioral results indicated significant offline gains in performance speed after sleep whereas performance was only stabilized, but not enhanced, after sleep deprivation. At the cerebral level, we previously showed that responses in the caudate nucleus increase, in parallel to a decrease in its functional connectivity with frontal areas, as performance became more consistent. Here, the strength of the competitive interaction, assessed through functional connectivity analyses, between the caudate nucleus and hippocampo-frontal areas during initial training, predicted delayed gains in performance at retest in sleepers but not in sleep-deprived subjects. Moreover, during retest, responses increased in the hippocampus and medial prefrontal cortex in sleepers whereas in sleep-deprived subjects, responses increased in the putamen and cingulate cortex. Our results suggest that the strength of the competitive interplay between the striatum and the hippocampus, participating in the implementation of consistent motor behavior during initial training, conditions subsequent motor sequence memory consolidation. The latter process appears to be supported by a reorganisation of cerebral activity in hippocampo-neocortical networks after sleep.

  12. Subjective and objective napping and sleep in older adults: are evening naps "bad" for nighttime sleep?

    Science.gov (United States)

    Dautovich, Natalie D; McCrae, Christina S; Rowe, Meredeth

    2008-09-01

    To compare objective and subjective measurements of napping and to examine the relationship between evening napping and nocturnal sleep in older adults. For 12 days, participants wore actigraphs and completed sleep diaries. Community. One hundred individuals who napped, aged 60 to 89 (including good and poor sleepers with typical age-related medical comorbidities). Twelve days of sleep diary and actigraphy provided subjective and objective napping and sleep data. Evening naps (within 2 hours of bedtime) were characteristic of the sample, with peak nap time occurring between 20:30 and 21:00 (average nap time occurred between 14:30 and 15:00). Two categories of nappers were identified: those who took daytime and evening naps and daytime-only. No participants napped during the evening only. Day-and-evening nappers significantly underreported evening napping and demonstrated lower objectively measured sleep onset latencies (20.0 vs 26.5 minutes), less wake after sleep onset (51.4 vs 72.8 minutes), and higher sleep efficiencies (76.8 vs 82%) than daytime-only nappers. Day and evening napping was prevalent in this sample of community-dwelling good and poor sleepers but was not associated with impaired nocturnal sleep. Although the elimination or restriction of napping is a common element of cognitive-behavioral therapy for insomnia, these results suggest that a uniform recommendation to restrict or eliminate napping (particularly evening napping) may not meet the needs of all older individuals with insomnia.

  13. Subjective and Objective Napping and Sleep in Older Adults: Are Evening Naps ‘Bad’ for Nighttime Sleep?

    Science.gov (United States)

    Dautovich, Natalie D.; McCrae, Christina S.; Rowe, Meredeth

    2014-01-01

    Objectives To compare objective and subjective measurements of napping, and to examine the relationship between evening napping and nocturnal sleep in older adults. Design For twelve days, participants wore actigraphs and completed sleep diaries. Setting Community Participants 100 individuals who napped, 60–89 years (including good and poor sleepers with typical age-related medical comorbidities). Measurements Twelve days of sleep diary and actigraphy provided subjective and objective napping and sleep data. Results Evening naps (within 2 hours of bedtime) were characteristic of the sample with peak nap time occurring between 20:30–21:00 (average nap time occurred between 14:30–15:00). Two categories of nappers were identified: 1) day/evening – those who took both daytime and evening naps, and 2) daytime-only. Interestingly, no participants napped during the evening only. Day/evening nappers significantly underreported evening napping and demonstrated lower objectively measured sleep onset latencies (20 vs 26.5 minutes), less wake after sleep onset (51.4 vs 72.8 minutes), and higher sleep efficiencies (76.8 vs 82%) than daytime-only nappers. Conclusion Day/evening napping was prevalent amongst this sample of community-dwelling good/poor sleepers, but was not associated with impaired nocturnal sleep. Although the elimination or restriction of napping is a common element of cognitive-behavioral therapy for insomnia (CBTi), these results suggest that a uniform recommendation to restrict/eliminate napping (particularly evening napping) may not meet the needs of all older individuals with insomnia. PMID:18691289

  14. Nocturnal insomnia symptoms and stress-induced cognitive intrusions in risk for depression: A 2-year prospective study.

    Science.gov (United States)

    Kalmbach, David A; Pillai, Vivek; Drake, Christopher L

    2018-01-01

    Nearly half of US adults endorse insomnia symptoms. Sleep problems increase risk for depression during stress, but the mechanisms are unclear. During high stress, individuals having difficulty falling or staying asleep may be vulnerable to cognitive intrusions after stressful events, given that the inability to sleep creates a period of unstructured and socially isolated time in bed. We investigated the unique and combined effects of insomnia symptoms and stress-induced cognitive intrusions on risk for incident depression. 1126 non-depressed US adults with no history of DSM-5 insomnia disorder completed 3 annual web-based surveys on sleep, stress, and depression. We examined whether nocturnal insomnia symptoms and stress-induced cognitive intrusions predicted depression 1y and 2y later. Finally, we compared depression-risk across four groups: non-perseverators with good sleep, non-perseverators with insomnia symptoms, perseverators with good sleep, and perseverators with insomnia symptoms. Insomnia symptoms (β = .10-.13, p good sleeping non-perseverators had the lowest rates (3.3%, Relative Risk = 3.94). Perseverators with sleep latency >30 m reported greater depression than good sleeping perseverators (t = 2.09, p stress creates a depressogenic mindset, and nocturnal wakefulness may augment the effects of cognitive arousal on depression development. Poor sleepers may be especially vulnerable to cognitive intrusions when having difficulty initiating sleep. As treatable behaviors, nighttime wakefulness and cognitive arousal may be targeted to reduce risk for depression in poor sleepers.

  15. A dynamic wheel-rail impact analysis of railway track under wheel flat by finite element analysis

    Science.gov (United States)

    Bian, Jian; Gu, Yuantong; Murray, Martin Howard

    2013-06-01

    Wheel-rail interaction is one of the most important research topics in railway engineering. It involves track impact response, track vibration and track safety. Track structure failures caused by wheel-rail impact forces can lead to significant economic loss for track owners through damage to rails and to the sleepers beneath. Wheel-rail impact forces occur because of imperfections in the wheels or rails such as wheel flats, irregular wheel profiles, rail corrugations and differences in the heights of rails connected at a welded joint. A wheel flat can cause a large dynamic impact force as well as a forced vibration with a high frequency, which can cause damage to the track structure. In the present work, a three-dimensional finite element (FE) model for the impact analysis induced by the wheel flat is developed by the use of the FE analysis (FEA) software package ANSYS and validated by another validated simulation. The effect of wheel flats on impact forces is thoroughly investigated. It is found that the presence of a wheel flat will significantly increase the dynamic impact force on both rail and sleeper. The impact force will monotonically increase with the size of wheel flats. The relationships between the impact force and the wheel flat size are explored from this FEA and they are important for track engineers to improve their understanding of the design and maintenance of the track system.

  16. Modern technologies of local injection anesthesia in dental practice

    Directory of Open Access Journals (Sweden)

    Sohov S.Т.

    2013-09-01

    Full Text Available Objective: To assess the importance of using the new system Quick Sleeper for local anesthesia, to highlight benefits of quick and comfortable anesthesia. Material and Methods. The examination of effectiveness, convenience of this kind of anesthesia has been carried out. Results. All patients, taking part in this examination, confirmed more comfortable condition after this anesthesia than conductor and infiltration methods of anesthesia. The effect of anesthesia is better than after conductor anesthesia. Conclusion. This technology guarantees equal introduction and spread of anesthetic, independently of tissue density, eliminating the risk of carpule breakage.

  17. Effect of cataract surgery on regulation of circadian rhythms

    DEFF Research Database (Denmark)

    Erichsen, Jesper Høiberg; Brøndsted, Adam E; Kessel, Line

    2015-01-01

    was evaluated based on the principles described in the Grading of Recommendations Assessment, Development, and Evaluation system. A literature search of PubMed, Embase, and Cochrane Library databases was performed, as well as a search for unpublished trials at the U.S. National Institutes of Health Clinical...... Trials web site. Trials that reported the effect of cataract surgery on circadian rhythms were included. Outcomes were the Pittsburgh Sleep Quality Index (PSQI) global score, number of poor sleepers, Epworth Sleepiness Score, sleep efficiency, and mean concentration of melatonin. Cataract surgery...

  18. No improvement in race performance by naps in male ultra-endurance cyclists in a 600-km ultra-cycling race.

    Science.gov (United States)

    Knechtle, Beat; Wirth, Andrea; Knechtle, Patrizia; Rüst, Christoph Alexander; Rosemann, Thomas; Lepers, Romuald

    2012-04-30

    Ultra-endurance performance is of increasing popularity. We investigated the associations between anthropometry, training and support during racing, with race performance in 67 male recreational ultra-endurance cyclists participating in the 'Swiss Cycling Marathon' over 600 kilometres, an official qualifier for the cycling ultra-marathon 'Paris-Brest-Paris'. The 54 finishers showed no differences in anthropometry and did not train differently compared to the 13 non-finishers. During the race, the finishers were significantly more frequently racing alone than being followed by a support crew. After bivariate analysis, percent body fat (r = 0.43), the cycling distance per training unit (r = -0.36), the duration per training unit (r = -0.31) and the sleep time during the race (r = 0.50) were related to overall race time. The 23 non-sleepers in the finisher group completed the race within (mean and IQR) 1,567 (1,453-1,606) min, highly significantly faster than the 31 sleepers with 1,934 (1,615-2,033) min (P = 0.0003). No variable of support during the race was associated with race time. After multivariate analysis, percent body fat (P = 0.026) and duration per training unit (P = 0.005) remained predictor variables for race time. To summarize, for a successful finish in a cycling ultra-marathon over 600 kilometres such as the 'Swiss Cycling Marathon', percent body fat and duration per training unit were related to race time whereas equipment and support during the race showed no association. Athletes with naps were highly significantly slower than athletes without naps.

  19. Enhancing CBT for Chronic Insomnia: A Randomised Clinical Trial of Additive Components of Mindfulness or Cognitive Therapy.

    Science.gov (United States)

    Wong, Mei Yin; Ree, Melissa J; Lee, Christopher W

    2016-09-01

    Although cognitive behavioural therapy (CBT) for insomnia has resulted in significant reductions in symptoms, most patients are not classified as good sleepers after treatment. The present study investigated whether additional sessions of cognitive therapy (CT) or mindfulness-based therapy (MBT) could enhance CBT in 64 participants with primary insomnia. All participants were given four sessions of standard CBT as previous research had identified this number of sessions as an optimal balance between therapist guidance and patient independence. Participants were then allocated to further active treatment (four sessions of CT or MBT) or a no further treatment control. The additional treatments resulted in significant improvements beyond CBT on self-report and objective measures of sleep and were well tolerated as evidenced by no dropouts from either treatment. The effect sizes for each of these additional treatments were large and clinically significant. The mean scores on the primary outcome measure, the Insomnia Severity Index, were 5.74 for CT and 6.69 for MBT, which are within the good-sleeper range. Treatment effects were maintained at follow-up. There were no significant differences between CT and MBT on any outcome measure. These results provide encouraging data on how to enhance CBT for treatment of insomnia. Copyright © 2015 John Wiley & Sons, Ltd. CBT treatments for insomnia can be enhanced using recent developments in cognitive therapy. CBT treatments for insomnia can be enhanced using mindfulness-based treatments. Both cognitive therapy and mindfulness produce additional clinically significant change. Copyright © 2015 John Wiley & Sons, Ltd.

  20. The effect of shift rotation on employee cortisol profile, sleep quality, fatigue, and attention level: a systematic review.

    Science.gov (United States)

    Niu, Shu-Fen; Chung, Min-Huey; Chen, Chiung-Hua; Hegney, Desley; O'Brien, Anthony; Chou, Kuei-Ru

    2011-03-01

    Disrupted circadian rhythm, especially working night duty together with irregular sleep patterns, sleep deprivation, and fatigue, creates an occupational health risk associated with diminished vigilance and work performance. This study reviewed the effect of shift rotations on employee cortisol profile, sleep quality, fatigue, and attention level. Researchers conducted a systematic review of relevant articles published between 1996 and 2008 that were listed on the following databases: SCOPUS, OVID, Blackwell Science, EBSCO Host, PsycINFO, Cochrane Controlled Trials Register, and CEPS. A total of 28 articles were included in the review. Previous research into the effects of shift work on cortisol profiles, sleep quality, fatigue, and attention used data assessed at evidence Levels II to IV. Our systematic review confirmed a conflict between sleep-wake cycle and light-dark cycle in night work. Consequences of circadian rhythm disturbance include disruption of sleep, decreased vigilance, general feeling of malaise, and decreased mental efficiency. Shift workers who sleep during the day (day sleepers) experience cortisol secretion increases, which diminish the healing power of sleep and enjoy 1 to 4 hours less sleep on average than night sleepers. Sleep debt accumulation results in chronic fatigue. Prolonged fatigue and inadequate recovery result in decreased work performance and more incidents. Rotation from day shift to night shift and its effect on shift workers was a special focus of the articles retained for review. Disturbed circadian rhythm in humans has been associated with a variety of mental and physical disorders and may negatively impact on work safety, performance, and productivity.

  1. Insomnia with objective short sleep duration is associated with longer duration of insomnia in the Freiburg Insomnia Cohort compared to insomnia with normal sleep duration, but not with hypertension.

    Science.gov (United States)

    Johann, Anna F; Hertenstein, Elisabeth; Kyle, Simon D; Baglioni, Chiara; Feige, Bernd; Nissen, Christoph; McGinness, Alastair J; Riemann, Dieter; Spiegelhalder, Kai

    2017-01-01

    To replicate the association between insomnia with objective short sleep duration and hypertension, type 2 diabetes and duration of insomnia. Retrospective case-control study. Department of Psychiatry and Psychotherapy, Medical Center-University of Freiburg. 328 patients with primary insomnia classified according to DSM-IV criteria (125 males, 203 females, 44.3 ± 12.2 years). N/A. All participants were investigated using polysomnography, blood pressure measurements, and fasting routine laboratory. Insomnia patients with short sleep duration (insomnia compared to those with normal sleep duration (≥ 6 hours) in the first night of laboratory sleep. Insomnia patients who were categorised as short sleepers in either night were not more likely to suffer from hypertension (systolic blood pressure of ≥ 140 mm Hg, diastolic blood pressure of ≥ 90 mm Hg, or a previously established diagnosis). Data analysis showed that insomnia patients with objective short sleep duration were not more likely to suffer from type 2 diabetes (fasting plasma glucose level of ≥ 126 mg/dl, or a previously established diagnosis). However, the diabetes analysis was only based on a very small number of diabetes cases. As a new finding, insomnia patients who were categorised as short sleepers in either night presented with increases in liver enzyme levels. The finding on insomnia duration supports the concept of two distinct sub-groups of insomnia, namely insomnia with, and without, objectively determined short sleep duration. However, our data challenges previous findings that insomnia patients with short sleep duration are more likely to suffer from hypertension.

  2. A review of a GP registrar-run mobile health clinic for homeless people.

    Science.gov (United States)

    O'Carroll, A; Irving, N; O'Neill, J; Flanagan, E

    2017-08-01

    Homeless people have excessively high morbidity and mortality rates, yet they face barriers accessing primary care. A mobile health clinic, staffed by GP registrars, was developed to provide services to homeless people, particularly rough sleepers and sex workers. The aims were to improve access to primary care and to challenge the stereotypes and prejudices of GP registrars through direct contact with homeless people. This was a qualitative study; questionnaires were completed on the mobile health clinic and two focus groups were conducted. All service users were asked to complete a questionnaire over a 3 month period. Two focus groups were conducted with 6 and 14 GP registrars who had worked on the bus. There was an 80% response rate (116 of 145). Fifty-two percent had no Medical Card meaning that they had no way to access the free primary care to which they are entitled. Had the clinic not been available, over half would not have sought further treatment and 16% would have gone to an Emergency Department. Ninety-one percent of users rated the service 10/10. The focus groups found that GP registrars who worked on the mobile health clinic had decreased negative stereotypes, increased empathy, and more knowledge of homeless issues. Furthermore, they intended to ensure that homeless people will not face discrimination in their future practice. A GP Registrar-run Mobile Health Clinic achieved its aims of improving access to primary care for rough sleepers and sex workers, and challenging stereotypes of GP Registrars.

  3. Tackling Health Disparities for People Who Are Homeless? Start with Social Determinants

    Science.gov (United States)

    Stafford, Amanda

    2017-01-01

    Background: Homelessness is associated with enormous health inequalities, including shorter life expectancy, higher morbidity and greater usage of acute hospital services. Viewed through the lens of social determinants, homelessness is a key driver of poor health, but homelessness itself results from accumulated adverse social and economic conditions. Indeed, in people who are homeless, the social determinants of homelessness and health inequities are often intertwined, and long term homelessness further exacerbates poor health. Aggregated health service data can mask this, and case histories thus provide important insights. Methods: This paper presents three case histories of homeless patients seen at an inner city public hospital in Perth, Western Australia. The case histories draw on several data sources: hospital data, information collected from rough sleepers and clinical observations. Estimates of the cost to the health system of the observed hospital usage by the three patients are included. Findings: The case histories illustrate the interplay of social determinants of health in homelessness that help explain the high level of hospital usage by rough sleepers. The cumulative healthcare costs for the three individuals over a 33 months period were substantial. Hospital attendance plummeted even in the short term when housing needs were addressed. Conclusions: Treating homelessness as a combined health and social issue is critical to improving the abysmal health outcomes of people experiencing homelessness. In addition, the enormous economic costs of hospital care for people who are homeless can be reduced when housing and other social determinants are taken into account. PMID:29292758

  4. American time use survey: sleep time and its relationship to waking activities.

    Science.gov (United States)

    Basner, Mathias; Fomberstein, Kenneth M; Razavi, Farid M; Banks, Siobhan; William, Jeffrey H; Rosa, Roger R; Dinges, David F

    2007-09-01

    To gain some insight into how various behavioral (lifestyle) factors influence sleep duration, by investigation of the relationship of sleep time to waking activities using the American Time Use Survey (ATUS). Cross-sectional data from ATUS, an annual telephone survey of a population sample of US citizens who are interviewed regarding how they spent their time during a 24-hour period between 04:00 on the previous day and 04:00 on the interview day. Data were pooled from the 2003, 2004, and 2005 ATUS databases involving N=47,731 respondents older than 14 years of age. N/A. Adjusted multiple linear regression models showed that the largest reciprocal relationship to sleep was found for work time, followed by travel time, which included commute time. Only shorter than average sleepers (socializing, relaxing, and engaging in leisure activities, while both short ( or =8.5 h) watched more TV than the average sleeper. The extent to which sleep time was exchanged for waking activities was also shown to depend on age and gender. Sleep time was minimal while work time was maximal in the age group 45-54 yr, and sleep time increased both with lower and higher age. Work time, travel time, and time for socializing, relaxing, and leisure are the primary activities reciprocally related to sleep time among Americans. These activities may be confounding the frequently observed association between short and long sleep on one hand and morbidity and mortality on the other hand and should be controlled for in future studies.

  5. Tackling Health Disparities for People Who Are Homeless? Start with Social Determinants

    Directory of Open Access Journals (Sweden)

    Amanda Stafford

    2017-12-01

    Full Text Available Background: Homelessness is associated with enormous health inequalities, including shorter life expectancy, higher morbidity and greater usage of acute hospital services. Viewed through the lens of social determinants, homelessness is a key driver of poor health, but homelessness itself results from accumulated adverse social and economic conditions. Indeed, in people who are homeless, the social determinants of homelessness and health inequities are often intertwined, and long term homelessness further exacerbates poor health. Aggregated health service data can mask this, and case histories thus provide important insights. Methods: This paper presents three case histories of homeless patients seen at an inner city public hospital in Perth, Western Australia. The case histories draw on several data sources: hospital data, information collected from rough sleepers and clinical observations. Estimates of the cost to the health system of the observed hospital usage by the three patients are included. Findings: The case histories illustrate the interplay of social determinants of health in homelessness that help explain the high level of hospital usage by rough sleepers. The cumulative healthcare costs for the three individuals over a 33 months period were substantial. Hospital attendance plummeted even in the short term when housing needs were addressed. Conclusions: Treating homelessness as a combined health and social issue is critical to improving the abysmal health outcomes of people experiencing homelessness. In addition, the enormous economic costs of hospital care for people who are homeless can be reduced when housing and other social determinants are taken into account.

  6. Insomnia with physiological hyperarousal is associated with hypertension.

    Science.gov (United States)

    Li, Yun; Vgontzas, Alexandros N; Fernandez-Mendoza, Julio; Bixler, Edward O; Sun, Yuanfeng; Zhou, Junying; Ren, Rong; Li, Tao; Tang, Xiangdong

    2015-03-01

    Previous studies have suggested that insomnia with objective short sleep duration is associated with a higher risk of hypertension, and it has been speculated that the underlying mechanism is physiological hyperarousal. In this study, we tested whether insomnia with physiological hyperarousal measured by Multiple Sleep Latency Test (MSLT), a standard test of sleepiness/alertness, is associated with increased risk of hypertension. Two hundred nineteen chronic insomniacs and 96 normal sleepers were included in this study. Chronic insomnia was defined based on standard diagnostic criteria with symptoms lasting ≥6 months. All subjects underwent 1 night in laboratory polysomnography followed by a standard MSLT. We used the median mean MSLT value (ie, >14 minutes) and the 75th percentile of mean MSLT value (ie, >17 minutes) to define hyperarousal. Hypertension was defined based either on blood pressure measures or on diagnosis treatment by a physician. After controlling for age, sex, body mass index, apnea-hypopnea index, diabetes mellitus, smoking, alcohol, and caffeine use, insomnia combined with MSLT >14 minutes increased the odds of hypertension by 300% (odds ratio=3.27; 95% confidence interval=1.20-8.96), whereas insomnia combined with MSLT >17 minutes increased even further the odds of hypertension by 400% (odds ratio=4.33; 95% confidence interval=1.48-12.68) compared with normal sleepers with MSLT ≤14 minutes. Insomnia associated with physiological hyperarousal is associated with a significant risk of hypertension. Long MSLT values may be a reliable index of the physiological hyperarousal and biological severity of chronic insomnia. © 2015 American Heart Association, Inc.

  7. Nocturnal insomnia symptoms and stress-induced cognitive intrusions in risk for depression: A 2-year prospective study

    Science.gov (United States)

    Pillai, Vivek; Drake, Christopher L.

    2018-01-01

    Nearly half of US adults endorse insomnia symptoms. Sleep problems increase risk for depression during stress, but the mechanisms are unclear. During high stress, individuals having difficulty falling or staying asleep may be vulnerable to cognitive intrusions after stressful events, given that the inability to sleep creates a period of unstructured and socially isolated time in bed. We investigated the unique and combined effects of insomnia symptoms and stress-induced cognitive intrusions on risk for incident depression. 1126 non-depressed US adults with no history of DSM-5 insomnia disorder completed 3 annual web-based surveys on sleep, stress, and depression. We examined whether nocturnal insomnia symptoms and stress-induced cognitive intrusions predicted depression 1y and 2y later. Finally, we compared depression-risk across four groups: non-perseverators with good sleep, non-perseverators with insomnia symptoms, perseverators with good sleep, and perseverators with insomnia symptoms. Insomnia symptoms (β = .10–.13, p insomnia had the highest rates of depression (13.0%), whereas good sleeping non-perseverators had the lowest rates (3.3%, Relative Risk = 3.94). Perseverators with sleep latency >30 m reported greater depression than good sleeping perseverators (t = 2.09, p < .04). Cognitive intrusions following stress creates a depressogenic mindset, and nocturnal wakefulness may augment the effects of cognitive arousal on depression development. Poor sleepers may be especially vulnerable to cognitive intrusions when having difficulty initiating sleep. As treatable behaviors, nighttime wakefulness and cognitive arousal may be targeted to reduce risk for depression in poor sleepers. PMID:29438400

  8. Cortical Thinning and Altered Cortico-Cortical Structural Covariance of the Default Mode Network in Patients with Persistent Insomnia Symptoms.

    Science.gov (United States)

    Suh, Sooyeon; Kim, Hosung; Dang-Vu, Thien Thanh; Joo, Eunyeon; Shin, Chol

    2016-01-01

    Recent studies have suggested that structural abnormalities in insomnia may be linked with alterations in the default-mode network (DMN). This study compared cortical thickness and structural connectivity linked to the DMN in patients with persistent insomnia (PI) and good sleepers (GS). The current study used a clinical subsample from the longitudinal community-based Korean Genome and Epidemiology Study (KoGES). Cortical thickness and structural connectivity linked to the DMN in patients with persistent insomnia symptoms (PIS; n = 57) were compared to good sleepers (GS; n = 40). All participants underwent MRI acquisition. Based on literature review, we selected cortical regions corresponding to the DMN. A seed-based structural covariance analysis measured cortical thickness correlation between each seed region of the DMN and other cortical areas. Association of cortical thickness and covariance with sleep quality and neuropsychological assessments were further assessed. Compared to GS, cortical thinning was found in PIS in the anterior cingulate cortex, precentral cortex, and lateral prefrontal cortex. Decreased structural connectivity between anterior and posterior regions of the DMN was observed in the PIS group. Decreased structural covariance within the DMN was associated with higher PSQI scores. Cortical thinning in the lateral frontal lobe was related to poor performance in executive function in PIS. Disrupted structural covariance network in PIS might reflect malfunctioning of antero-posterior disconnection of the DMN during the wake to sleep transition that is commonly found during normal sleep. The observed structural network alteration may further implicate commonly observed sustained sleep difficulties and cognitive impairment in insomnia. © 2016 Associated Professional Sleep Societies, LLC.

  9. Contribution of Inflammation, Oxidative Stress, and Antioxidants to the Relationship between Sleep Duration and Cardiometabolic Health.

    Science.gov (United States)

    Kanagasabai, Thirumagal; Ardern, Chris I

    2015-12-01

    To explore the interrelationship and mediating effect of factors that are beneficial (i.e., antioxidants) and harmful (i.e., inflammation and oxidative stress) to the relationship between sleep and cardiometabolic health. Cross-sectional data from the 2005-2006 National Health and Nutrition Examination Survey. Nationally representative population sample from the US. Age ≥ 20 y with sleep data; final analytical sample of n = 2,079. N/A. Metabolic syndrome was classified according to the Joint Interim Statement, and sleep duration was categorized as very short, short, adequate, and long sleepers (≤ 4, 5-6, 7-8, and ≥ 9 h per night, respectively). The indirect mediation effect was quantified as large (≥ 0.25), moderate (≥ 0.09), modest (≥ 0.01), and weak (sleep duration categories, whereas oxidative stress was elevated among short and very short sleepers. Select sleep duration- cardiometabolic health relationships were mediated by C-reactive protein (CRP), γ-glutamyl transferase (GGT), carotenoids, uric acid, and vitamins C and D, and were moderated by sex. Specifically, moderate-to-large indirect mediation by GGT, carotenoids, uric acid, and vitamin D were found for sleep duration-waist circumference and -systolic blood pressure relationships, whereas vitamin C was a moderate mediator of the sleep duration-diastolic blood pressure relationship. Several factors related to inflammation, oxidative stress, and antioxidant status were found to lie on the casual pathway of the sleep duration-cardiometabolic health relationship. Further longitudinal studies are needed to confirm our results. © 2015 Associated Professional Sleep Societies, LLC.

  10. Displacement monitoring of switch track and its slab on a bridge of high speed railway by FBG

    Science.gov (United States)

    Li, Weilai; Li, He; Cheng, Jian; Huang, Xiaomei; Pan, Jianjun; Zhou, Ciming; Yang, Minghong

    2011-05-01

    In a 350km/h high speed railway line, there is a seamless switch with ballastless slabs built on a bridge. 54 Fiber Bragg Grating detecting cells are employed to monitor the displacement of track and slab. The cell is of extending function of measurement range, up to 50mm displacement, and is of good linearity. Protecting methods for cells and fiber are adopted to keep them surviving from the harsh conditions. The results show that in 75 days, the displacement of the track and sleeper slab was 8-9mm, and the displacement is of high correlation with daily environmental temperature change.

  11. MODELING OF RAILWAY TRACK OPERATION AS A SYSTEM OF QUASI-ELASTIC ORTHOTROPIC LAYERS

    Directory of Open Access Journals (Sweden)

    Sychev Vyacheslav Petrovich

    2016-03-01

    Full Text Available In this paper the authors give a solution to the problem of the impact of a rolling stock on the rail track on the basis of modeling a railway track as a multi-layered space, introducing each of the layers is a quasi-elastic orthotropic layer with cylindrical anisotropy in the polar coordinate system. The article describes wave equations, taking into account the rotational inertia of cross sectional and transverse shear strains. From the point of view of classical structural mechanics train path can be represented as a multilayer system comprising separate layers with different stiffness, lying on the foundation being the elastic-isotropic space. Winkler model provides that the basis is linearly deformable space, there are loads influencing its surface. These loads are transferred through a layered deformable half-space. This representation is used in this study as an initial approximation. For more accurate results of the deformation of a railway track because of rolling dynamic loads it is proposed to present a railway track in the form of a layered structure, where each element (assembled rails and sleepers, ballast section, the soil in the embankment, basement soils is modeled as a planar quasi-elastic orthotropic layer with cylindrical anisotropy. The equations describing the dynamic behaviour of flat element in a polar coordinate system are hyperbolic in nature and take into account the rotational inertia of the cross sectional and the transverse shear strains. This allows identifying the impact on the final characteristics of the blade wave effects, and oscillatory processes. In order to determine the unknown functions included in the constitutive equations it is proposed to use decomposition in power series in spatial coordinate and time. In order to determine the coefficients of ray series for the required functions, it is necessary to differentiate the defining wave equations k times on time, to take their difference on the different

  12. Objective measures of sleep duration and continuity in major depressive disorder with comorbid hypersomnolence: a primary investigation with contiguous systematic review and meta-analysis.

    Science.gov (United States)

    Plante, David T; Cook, Jesse D; Goldstein, Michael R

    2017-06-01

    Hypersomnolence plays an important role in the presentation, treatment and course of mood disorders. However, there has been relatively little research that examines objective measures of sleep duration and continuity in patients with depression and hypersomnolence, despite the use of these factors in sleep medicine nosological systems. This study compared total sleep time and efficiency measured by naturalistic actigraphic recordings followed by ad libitum polysomnography (PSG; without prescribed wake time) in 22 patients with major depressive disorder and co-occurring hypersomnolence against age- and sex-matched healthy sleeper controls. The major depressive disorder and co-occurring hypersomnolence group demonstrated significantly longer sleep duration compared with healthy sleeper controls quantified by sleep diaries, actigraphy and ad libitum PSG. No between-group differences in sleep efficiency (SE), latency to sleep or wake after sleep onset were observed when assessed using objective measures. To further contextualize these findings within the broader scientific literature, a systematic review was performed to identify other comparable investigations. A meta-analysis of pooled data demonstrated patients with mood disorders and co-occurring hypersomnolence have significantly greater sleep duration and similar SE compared with healthy controls when assessed using ad libitum PSG. These results suggest current sleep medicine nosology that distinguishes hypersomnia associated with psychiatric disorders primarily as a construct characterized by low SE and increased time in bed may not be accurate. Future studies that establish the biological bases hypersomnolence in mood disorders, as well as clarify the accuracy of nosological thresholds to define excessive sleep duration, are needed to refine the diagnosis and treatment of these disorders. © 2017 European Sleep Research Society.

  13. Emotional memory processing is influenced by sleep quality.

    Science.gov (United States)

    Tempesta, Daniela; De Gennaro, Luigi; Natale, Vincenzo; Ferrara, Michele

    2015-07-01

    The recall of emotional memory is enhanced after sleep and is hindered by sleep deprivation. We used an emotional memory task to assess whether poor sleep quality, as well as sleep deprivation, may influence the accuracy of memory recognition, but also the affective tone associated with the memory. Seventy-five subjects, divided into poor sleeper (PS), good sleeper (GS), and sleep deprivation (SD) groups, completed two recall (R) sessions: R1, 1 h after the encoding phase; and R2, after one night of sleep for PS and GS groups and after one night of sleep deprivation for the SD group. During the encoding phase, the participants rated valence and arousal of 90 pictures. During R1 and R2, the participants first made a yes/no memory judgment of the 45 target pictures intermingled with 30 non-target pictures, then rated valence and arousal of each picture. Recognition accuracy was higher for the PS and GS groups compared to the SD group for all pictures. Emotional valence of the remembered pictures was more negative after sleep deprivation and poor quality sleep, while it was preserved after a good sleep. These results provide the first evidence that poor sleep quality negatively affects emotional valence of memories, within the context of preserved emotional memory consolidation. It is suggested that low sleep quality and lack of sleep may impose a more negative affective tone to memories. The reported effects are not to be ascribed to depressive mood, but to a specific influence of poor sleep quality. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Predicting synergistic effects of resources and predators on foraging decisions by juvenile Steller sea lions.

    Science.gov (United States)

    Frid, Alejandro; Burns, Jennifer; Baker, Gregory G; Thorne, Richard E

    2009-01-01

    Many theoretical and experimental studies suggest that synergistic interactions between resources and predators influence foraging decisions and their fitness consequences. This framework, however, has been ignored almost completely by hypotheses on causes of the population decline of Steller sea lions (SSLs) (Eumetopias jubatus) in western Alaska. By comparing predictions from a dynamic state variable model to empirical data on the behaviour of individuals instrumented with satellite-linked time-at-depth recorders, we develop and find preliminary support for the hypothesis that, during winter in Prince William Sound, juvenile SSLs (a) underutilise walleye pollock, a predictable resource in deep strata, due to predation risk from Pacific sleeper sharks, and (b) underutilise the potential energy bonanza of inshore aggregations of Pacific herring due to risk from either killer whales, larger conspecifics, or both. Further, under conditions of resource scarcity-induced by overfishing, long-term oceanographic cycles, or their combination-trade-offs between mortality risk and energy gain may influence demographic parameters. Accordingly, computer simulations illustrated the theoretical plausibility that a decline of Pacific herring in shallow strata would greatly increase the number of deep foraging dives, thereby increasing exposure to sleeper sharks and mortality rates. These results suggest that hypotheses on the decline of SSLs should consider synergistic effects of predators and resources on behaviour and mortality rates. Empirical support for our model, however, is limited and we outline tasks for empirical research that emerge from these limitations. More generally, in the context of today's conservation crises, our work illustrates that the greater the dearth of system-specific data, the greater the need to apply principles of behavioural ecology toward the understanding and management of large-scale marine systems.

  15. Attention bias for sleep-related stimuli in primary insomnia and delayed sleep phase syndrome using the dot-probe task.

    Science.gov (United States)

    MacMahon, Kenneth M A; Broomfield, Niall M; Espie, Colin A

    2006-11-01

    Cognitive models of primary insomnia (PI) suggest attention bias as a maintaining process. This study used a hallmark measure of attention bias, the dot-probe task, to determine whether attention bias to sleep-related stimuli is present in individuals with PI. Control groups of good sleepers (GS) and individuals with delayed sleep phase syndrome (DSPS), a sleep disorder with no presumed cognitive pathway and, hence, no predicted association with attention bias, were included. A between-groups (PI, DSPS, GS) design was employed. Participants completed a dot-probe task with stimuli comprising sleep-related and neutral words, balanced for length and frequency of usage. It was predicted a priori that PI would show greater attention bias to sleep stimuli compared with GS and DSPS groups. No difference between GS and DSPS was predicted. Sixty-three individuals completed the study (PI = 21; DSPS = 22; GS = 20), with those in PI and DSPS classified by International Classification of Sleep Disorders criteria according to self-report sleep diaries and actigraphy. GS scored Sleep Quality Index, reported being good sleepers, and met no criteria for a current or previous sleep disorder. N/A. As predicted, PI showed increased vigilance for sleep-related stimuli relative to GS and DSPS. No differences between GS and those with DSPS were found. The PI group showed shorter response latencies relative to the GS and DSPS groups. Results support an association between attention bias and PI. Further work must determine whether or not attention bias is a causal factor. Speeded responses in the PI group suggest heightened arousal, indicating that physiologic factors may play a related role.

  16. Depression and quality of sleep in maintenance hemodialysis patients

    Directory of Open Access Journals (Sweden)

    Trbojević-Stanković Jasna

    2014-01-01

    Full Text Available Introduction. Sleep disorders and psychological disturbances are common in end-stage renal disease (ESRD patients. However, despite their frequency and importance, such conditions often go unnoticed, since all patients do not clearly manifest fully expressed symptoms. Objective. This study aimed to determine the prevalence of depression and poor sleep quality and to examine the association between these disorders and demographic, clinical and treatment-related characteristics of ESRD patients on hemodialysis (HD. Methods. The study included 222 patients (132 men and 90 women, mean age 57.3±11.9 years, from 3 HD centers in Central Serbia, which provided us with biochemical parameters and demographic data. Sleep quality and depression were assessed using the Pittsburgh Sleep Quality Index (PSQI and Beck Depression Inventory (BDI, respectively. Results. The average BDI was 16.1±11.3. Depressed patients were significantly older (p=0.041, had a significantly lower dialysis adequacy (p=0.027 and a significantly worse quality of sleep (p<0.001, while they did not show significant difference as regarding sex, employment, marital status, comorbidities, dialysis type, dialysis vintage, shift and laboratory parameters. The average PSQI was 7.8±4.5 and 64.2% of patients were poor sleepers. Poor sleepers were significantly older (p=0.002, they were more often females (p=0.027 and had a significantly higher BDI (p<0.001, while other investigated variables were not correlated with sleep quality. A statistically significant positive correlation was found between BDI and PSQI (r=0.604; p<0.001. Conclusion. Depression and poor sleep quality are frequent and interrelated among HD patients.

  17. Insomnia and Relationship with Anxiety in University Students: A Cross-Sectional Designed Study.

    Directory of Open Access Journals (Sweden)

    Nour Choueiry

    Full Text Available Sleep disorders (SDs are now recognized as a public health concern with considerable psychiatric and societal consequences specifically on the academic life of students. The aims of this study were to assess SDs in a group of university students in Lebanon and to examine the relationship between SDs and anxiety.An observational cross-sectional study was conducted at Saint-Joseph University, Lebanon, during the academic year 2013-2014. Four questionnaires were face-to-face administered to 462 students after obtaining their written consent: Insomnia Severity Index (ISI, Pittsburgh Sleep Quality Index (PSQI, Epworth Sleepiness Scale (ESS, and Generalized Anxiety Disorder 7-item scale (GAD-7.The prevalence of clinically significant insomnia was 10.6% (95% CI: 7.8-13.4%, more frequent in first year students. ISI mean score was 10.06 (SD = 3.76. 37.1% of the participants were poor sleepers. Excessive daytime sleepiness (EDS and poor sleep were significantly more frequent among participants with clinical insomnia (p = 0.031 and 0.001 respectively. Clinically significant anxiety was more frequent in students suffering from clinical insomnia (p = 0.006 and in poor sleepers (p = 0.003. 50.8% of the participants with clinically significant anxiety presented EDS versus 30.9% of those with no clinically significant anxiety (p<0.0001.The magnitude of SDs in this sample of Lebanese university students demonstrate the importance of examining sleep health in this population. Moreover, the link between SD and anxiety reminds us of the importance of treating anxiety as soon as detected and not simply targeting the reduction of sleep problems.

  18. Relationship between sleep pattern and efficacy of calorie-restricted Mediterranean diet in overweight/obese subjects.

    Science.gov (United States)

    Pagliai, Giuditta; Dinu, Monica; Casini, Alessandro; Sofi, Francesco

    2018-02-01

    The association between the sleep pattern and the effectiveness of a calorie-restricted Mediterranean diet in people with overweight/obesity has been investigated in this study. Four hundred and three subjects were provided with a calorie-restricted Mediterranean diet and followed for 9 months. Personal information, including sleep pattern, was obtained at the baseline. Body weight and composition were measured every 3 months. Poor sleepers reported to have significantly (p sleeping 6-8 or >8 h/day had an increased probability of losing fat mass than women who reported sleeping sleep pattern is necessary to maintain body weight and optimal body composition.

  19. Influence of temperature, mixing and time of residue on the degradation of organic trace materials during thermal treatment of waste wood; Einfluss von Temperatur, Durchmischung und Verweilzeit auf den Abbau organischer Spurenstoffe bei der thermischen Behandlung von Abfallholz

    Energy Technology Data Exchange (ETDEWEB)

    Beckmann, M [Clausthaler Umwelttechnik-Institut GmbH (CUTEC), Clausthal-Zellerfeld (Germany); Griebel, H [Fels-Werke GmbH, Goslar (Germany); Scholz, R [Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany). Inst. fuer Energieverfahrenstechnik und Brennstofftechnik

    1998-09-01

    Waste wood, e.g. window frames or sleepers treated with coal tar pitch, are usually incinerated after crushing and removal of foreign materials (glass, metal etc.). Organic trace elements, e.g. PAH, PCB, chlorobenzenes, PCDD and PCDF must be removed after combustion. (orig./SR) [Deutsch] Abfallhoelzer, wie z.B. Fensterrahmen oder mit Steinkohlenteerpech behandelte Eisenbahnschwellen, werden nach Zerkleinerung und Abtrennung von Wert- und Stoerstoffen (Glas, Metalle usw.) haeufig in Rostsystemen thermisch behandelt. Bei der Diskussion der Prozessbedingungen liegt ein besonderer Schwerpunkt in der Fragestellung nach geeigneten Abbaubedingungen fuer organische Spurenstoffe wie polyaromatische Kohlenwasserstoffe (PAK), polychlorierte Biphenyle (PCB), Chlorbenzole, polychlorierte Dibenzodioxine (PCDD) und polychlorierte Dibenzofurane (PCDF) im Nachverbrennungsprozess. (orig./SR)

  20. Prevalence of Clonorchis sinensis infection in freshwater fishes in northeastern China.

    Science.gov (United States)

    Zhang, Y; Chang, Q C; Zhang, Y; Na, L; Wang, W T; Xu, W W; Gao, D Z; Liu, Z X; Wang, C R; Zhu, X Q

    2014-08-29

    The prevalence of Clonorchis sinensis infection in freshwater fishes was surveyed in Heilongjiang Province, northeastern China, between August 2011 and September 2013. Thirteen species of freshwater fish (n=3221) and one species of shrimp (n=93) were collected from Songhua river, Nenjiang river and other lakes or ponds in 37 sites of 15 representative cities in Heilongjiang Province. They were individually examined by digestion technique, and the C. sinensis metacercariae were identified morphologically followed by confirmation using sequences of the second internal transcribed spacer of ribosomal DNA. Ten of the 13 examined species of freshwater fishes were infected with C. sinensis metacercariae, while all shrimps were negative. The overall prevalence of C. sinensis infection in 3221 examined freshwater fishes was 19.96%, with 42.57% (272/639) in Pseudorasbora parva, 22.55% (83/368) in Hemicculter leuciclus, 20.44% (121/592) in Carassius auratus, 17.71% (68/384) in Saurogobio dabryi, 10.85% (23/212) in Rhodeus ocellatus, 10.54% (48/455) in Phoxinus lagowskii, 8.20% (21/256) in Perccottus glehnii, 6.25% (5/80) in Misgurnus anguillicaudatus, 4.55% (1/22) in Xenocypris davidi, and 1.49% (1/67) in Cyprinus carpio. The average infection intensity in P. parva was 103.3 encysted metacercariae per gram of fish meat in Zhaoyuan city. The average prevalence of C. sinensis infection in Songhua river, Nenjiang river and lakes or ponds were 31.96% (503/1574), 11.30% (102/903) and 7.93% (59/744), respectively. The prevalence of C. sinensis infection in Zhaoyuan city (43.68%) was the highest among all sampling locations. These results revealed a high-prevalence of C. sinensis infection in freshwater fishes in Heilongjiang Province, northeastern China, posing significant public health concern. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Daily rhythms of the sleep-wake cycle

    Directory of Open Access Journals (Sweden)

    Waterhouse Jim

    2012-03-01

    Full Text Available Abstract The amount and timing of sleep and sleep architecture (sleep stages are determined by several factors, important among which are the environment, circadian rhythms and time awake. Separating the roles played by these factors requires specific protocols, including the constant routine and altered sleep-wake schedules. Results from such protocols have led to the discovery of the factors that determine the amounts and distribution of slow wave and rapid eye movement sleep as well as to the development of models to determine the amount and timing of sleep. One successful model postulates two processes. The first is process S, which is due to sleep pressure (and increases with time awake and is attributed to a 'sleep homeostat'. Process S reverses during slow wave sleep (when it is called process S'. The second is process C, which shows a daily rhythm that is parallel to the rhythm of core temperature. Processes S and C combine approximately additively to determine the times of sleep onset and waking. The model has proved useful in describing normal sleep in adults. Current work aims to identify the detailed nature of processes S and C. The model can also be applied to circumstances when the sleep-wake cycle is different from the norm in some way. These circumstances include: those who are poor sleepers or short sleepers; the role an individual's chronotype (a measure of how the timing of the individual's preferred sleep-wake cycle compares with the average for a population; and changes in the sleep-wake cycle with age, particularly in adolescence and aging, since individuals tend to prefer to go to sleep later during adolescence and earlier in old age. In all circumstances, the evidence that sleep times and architecture are altered and the possible causes of these changes (including altered S, S' and C processes are examined.

  2. Quality of sleep and health-related quality of life in renal transplant recipients.

    Science.gov (United States)

    Liu, Hong-Xia; Lin, Jun; Lin, Xiao-Hong; Wallace, Linda; Teng, Sha; Zhang, Shu-Ping; Hao, Yu-Fang

    2015-01-01

    The purpose of this study was to examine the sleep quality and health-related quality of life (HRQOL) in patients after renal transplantation and to explore the relationship between the quality of sleep and the HRQOL. Sleep disorders are still an important clinical problem after renal transplantation. Previous studies mainly focused on patients' sleep quality before kidney transplant. More studies are needed to document sleep quality after renal transplantation. A cross-sectional design was used in this study. A convenience sample of renal transplant recipients was recruited at an outpatient transplant clinic of a general hospital in Beijing, China. The Pittsburgh Sleep Quality Index (PSQI) was used to measure quality of sleep. The Medical Outcomes Study 36-item Short Form (MOS SF-36) was used to measure health-related quality of life. The average PSQI score of the 204 renal transplant recipients was 5.81±3.52, significantly lower than the norm. Fifty (24.5%) recipients were classified as having poor sleep quality (global PSQI > 7). The mean scores of renal transplant recipients for SF-36 Mental Component Summary (MCS) and Physical Component Summary (PCS) were 47.57±6.71 and 48.26±9.66 respectively. Compared with residents in Sichuan province, recipients' scores for SF-36 dimensions were statistically lower except the dimension of mental health. SF-36 scores of poor sleepers (PSQI > 7) were significantly lower than the good sleepers (PSQI ≤ 7) in both the MCS and PCS. Significant differences exist between the groups in physical function, bodily pain, vitality, and mental health dimensions. Sleep quality and HRQOL of patients after renal transplantation were lower than the norm. Poor sleep is associated with lower HRQOL. Health professionals need to pay attention to sleep quality and HRQOL in renal transplant recipients and take appropriate measures to improve patients' sleep quality and HRQOL.

  3. Prevalence of abnormal sleep duration and excessive daytime sleepiness in pregnancy and the role of socio-demographic factors: comparing pregnant women with women in the general population.

    Science.gov (United States)

    Signal, T Leigh; Paine, Sarah-Jane; Sweeney, Bronwyn; Priston, Monique; Muller, Diane; Smith, Alexander; Lee, Kathryn A; Huthwaite, Mark; Reid, Papaarangi; Gander, Philippa

    2014-12-01

    To compare the prevalence of self-reported abnormal sleep duration and excessive daytime sleepiness in pregnancy among Māori (indigenous New Zealanders) and non-Māori women versus the general population, and to examine the influence of socio-demographic factors. Self-reported total sleep time (TST) in 24-hrs, Epworth Sleepiness Scale scores and socio-demographic information were obtained from nullipara and multipara women aged 20-46 yrs at 35-37 weeks pregnant (358 Māori and 717 non-Māori), and women in the general population (381 Māori and 577 non-Māori). After controlling for ethnicity, age, socio-economic status, and employment status, pregnant women average 30 min less TST than women in the general population. The distribution of TST was also greater in pregnant women, who were 3 times more likely to be short sleepers (≤6 h) and 1.9 times more likely to be long sleepers (>9 h). In addition, pregnant women were 1.8 times more likely to report excessive daytime sleepiness (EDS). Pregnant women >30 years of age experienced greater age-related declines in TST. Identifying as Māori, being unemployed, and working at night increased the likelihood of reporting abnormal sleep duration across all women population in this study. EDS also more likely occurred among Māori women and women who worked at night. Pregnancy increases the prevalence of abnormal sleep duration and EDS, which are also higher among Māori than non-Māori women and those who do night work. Health professionals responsible for the care of pregnant women need to be well-educated about the importance of sleep and discuss sleep issues with the women they care for. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. The Natural History of Insomnia: Acute Insomnia and First-onset Depression

    Science.gov (United States)

    Ellis, Jason G.; Perlis, Michael L.; Bastien, Célyne H.; Gardani, Maria; Espie, Colin A.

    2014-01-01

    Study Objectives: While many studies have examined the association between insomnia and depression, no studies have evaluated these associations (1) within a narrow time frame, (2) with specific reference to acute and chronic insomnia, and (3) using polysomnography. In the present study, the association between insomnia and first-onset depression was evaluated taking into account these considerations. Design: A mixed-model inception design. Setting: Academic research laboratory. Participants: Fifty-four individuals (acute insomnia [n = 33], normal sleepers [n = 21]) with no reported history of a sleep disorder, chronic medical condition, or psychiatric illness. Interventions: N/A. Measurements and Results: Participants were assessed at baseline (2 nights of polysomnography and psychometric measures of stress and mood) and insomnia and depression status were reassessed at 3 months. Individuals with acute insomnia exhibited more stress, poorer mood, worse subjective sleep continuity, increased N2 sleep, and decreased N3 sleep. Individuals who transitioned to chronic insomnia exhibited (at baseline) shorter REM latencies and reduced N3 sleep. Individuals who exhibited this pattern in the transition from acute to chronic insomnia were also more likely to develop first-onset depression (9.26%) as compared to those who remitted from insomnia (1.85%) or were normal sleepers (1.85%). Conclusion: The transition from acute to chronic insomnia is presaged by baseline differences in sleep architecture that have, in the past, been ascribed to Major Depression, either as heritable traits or as acquired traits from prior episodes of depression. The present findings suggest that the “sleep architecture stigmata” of depression may actually develop over the course transitioning from acute to chronic insomnia. Citation: Ellis JG; Perlis ML; Bastien CH; Gardani M; Espie CA. The natural history of insomnia: acute insomnia and first-onset depression. SLEEP 2014;37(1):97-106. PMID

  5. Habitual sleep quality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women.

    Science.gov (United States)

    Huang, Tianyi; Poole, Elizabeth M; Vetter, Celine; Rexrode, Kathryn M; Kubzansky, Laura D; Schernhammer, Eva; Rohleder, Nicolas; Hu, Frank B; Redline, Susan; Tworoger, Shelley S

    2017-10-01

    Dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis has been suggested as a potential mechanism linking sleep and cardiometabolic disorders. However, the associations of two primary outputs of the HPA axis, cortisol and its antagonist dehydroepiandrosterone (DHEA), with sleep are less well studied. In the Nurses' Health Study II, 233 postmenopausal women provided five timed saliva samples over one day (immediately upon waking, 45min, 4h, and 10h after waking, and prior to going to sleep) to measure cortisol and DHEA. Of these, 209 completed assessment of their habitual sleep patterns using the Pittsburgh Sleep Quality Index (PSQI). We used piecewise linear mixed models to compare cross-sectional associations of slopes reflecting diurnal cortisol and DHEA rhythms with overall sleep quality and with seven sub-components. Overall, we observed no differences in the diurnal patterns of cortisol or DHEA between good versus poor sleepers as assessed by the global PSQI score. However, longer sleep latency was associated with significantly reduced cortisol awakening rise (p=0.02). Poorer subjective sleep quality (p=0.02), shorter sleep duration (p=0.02), and lower sleep efficiency (p=0.03) were associated with slower rate of cortisol decline later in the day. Women reporting daytime dysfunction had a sharper cortisol decline early in the day (p=0.03) but a flattened decline later in the day (p=0.01). The differences in diurnal patterns of DHEA between good versus poor sleepers, though less pronounced, were similar in direction to those of cortisol. Self-reported sleep duration, efficiency, latency and daytime dysfunction were associated with altered diurnal rhythms of cortisol and, to a lesser extent, DHEA. These findings provide support for the interplay between sleep and the HPA axis that may contribute to cardiometabolic disease. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Lack of Resilience Is Related to Stress-Related Sleep Reactivity, Hyperarousal, and Emotion Dysregulation in Insomnia Disorder.

    Science.gov (United States)

    Palagini, Laura; Moretto, Umberto; Novi, Martina; Masci, Isabella; Caruso, Danila; Drake, Christopher L; Riemann, Dieter

    2018-05-15

    According to the diathesis-stress model of insomnia, insomnia may develop in vulnerable individuals in response to stress. Resilience is a psychobiological factor that determines an individual's capacity to adapt successfully to stressful events and low resilience increases vulnerability for development of mental disorders. The aim was to explore resilience in subjects with insomnia and its relationship with the factors that contribute to its development and perpetuation. The study consisted of 58 subjects with Insomnia Disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and 38 good sleepers. Resilience Scale for Adults (RSA), Ford Insomnia Response to Stress Test (FIRST), Pre-sleep Arousal Scale (PSAS), and Difficulties in Emotion Regulation Scale (DERS) were administered while taking into account psychiatric symptoms. Differences in means between groups were assessed using t test or Mann-Whitney U /Wilcoxon test. Linear/multivariable regression analyses and mediation analyses were performed. Subjects with insomnia (24 females, mean age 49 ± 2.1 years) had lower RSA and higher FIRST, DERS, and PSAS scores than good sleepers (22 females, mean age 47.2 ± 1.2 years). After controlling for anxiety/depressive symptoms, low resilience correlated with high stress-related sleep reactivity ( P = .004), pre-sleep cognitive hyperarousal ( P = .01) and emotion dysregulation ( P = .01). Emotion dysregulation mediated the relationship between low resilience and cognitive hyperarousal (Z = 2.06, P = .03). Subjects with insomnia showed low resilience, which was related to high stress-related sleep reactivity, emotional dysregulation, and hyperarousal. If resilience helps to minimize the extent of pathogenesis in the developmental process, an early identification of vulnerable candidates should be useful for preventing insomnia development and maintenance. A commentary on this article appears in this issue on page 709. © 2018 American

  7. On-the-road driving performance and driving-related skills in older untreated insomnia patients and chronic users of hypnotics.

    Science.gov (United States)

    Leufkens, T R M; Ramaekers, J G; de Weerd, A W; Riedel, W J; Vermeeren, A

    2014-07-01

    Many older adults report sleep problems and use of hypnotics. Several studies have shown that hypnotics can have acute adverse effects on driving the next morning. It is unclear however whether driving of chronic hypnotic users is impaired. Therapeutic effects on insomnia and development of tolerance may reduce the residual effects on driving. The present study aimed to compare actual driving performance and driving-related skills of chronic hypnotic users to good sleepers. To determine whether insomnia itself affects driving performance, driving and driving-related skills were compared between insomnia patients who do not or infrequently use hypnotics and good sleepers. Twenty-two frequent users of hypnotics (using hypnotics ≥ 4 nights per week for more than 3 months), 20 infrequent users (using hypnotics ≤ 3 nights per week), and 21 healthy, age-matched controls participated in this study. On the night before testing, all subjects were hospitalized for an 8-h sleep recorded by polysomnography. Frequent hypnotic users used their regular medication at bedtime (2330 hours), while infrequent users and controls received no medication. Cognitive performance (word learning, digit span, tracking, divided attention, vigilance, and inhibitory control) was assessed 8.5 h and driving performance between 10 and 11 h after bedtime and dosing. Polysomnographic recordings did not significantly differ between the groups, but the insomnia patients, treated or untreated, still reported subjective sleep complaints. Results show no differences in driving performance and driving-related skills between both groups of insomnia patients and controls. Driving performance in chronic users of hypnotics and untreated insomnia patients is not impaired. For chronic users, this may be due to prescription of relatively safe drugs and low doses. For untreated insomniacs, this corroborates previous findings showing an absence of neuropsychological deficits in this group of patients.

  8. Comparison of total mercury and methylmercury cycling at five sites using the small watershed approach

    Science.gov (United States)

    Shanley, J.B.; Alisa, Mast M.; Campbell, D.H.; Aiken, G.R.; Krabbenhoft, D.P.; Hunt, R.J.; Walker, J.F.; Schuster, P.F.; Chalmers, A.; Aulenbach, Brent T.; Peters, N.E.; Marvin-DiPasquale, M.; Clow, D.W.; Shafer, M.M.

    2008-01-01

    The small watershed approach is well-suited but underutilized in mercury research. We applied the small watershed approach to investigate total mercury (THg) and methylmercury (MeHg) dynamics in streamwater at the five diverse forested headwater catchments of the US Geological Survey Water, Energy, and Biogeochemical Budgets (WEBB) program. At all sites, baseflow THg was generally less than 1 ng L-1 and MeHg was less than 0.2 ng L-1. THg and MeHg concentrations increased with streamflow, so export was primarily episodic. At three sites, THg and MeHg concentration and export were dominated by the particulate fraction in association with POC at high flows, with maximum THg (MeHg) concentrations of 94 (2.56) ng L-1 at Sleepers River, Vermont; 112 (0.75) ng L-1 at Rio Icacos, Puerto Rico; and 55 (0.80) ng L-1 at Panola Mt., Georgia. Filtered (Colorado, THg export was also episodic but was dominated by filtered THg, as POC concentrations were low. MeHg typically tracked THg so that each site had a fairly constant MeHg/THg ratio, which ranged from near zero at Andrews to 15% at the low-relief, groundwater-dominated Allequash Creek, Wisconsin. Allequash was the only site with filtered MeHg consistently above detection, and the filtered fraction dominated both THg and MeHg. Relative to inputs in wet deposition, watershed retention of THg (minus any subsequent volatilization) was 96.6% at Allequash, 60% at Sleepers, and 83% at Andrews. Icacos had a net export of THg, possibly due to historic gold mining or frequent disturbance from landslides. Quantification and interpretation of Hg dynamics was facilitated by the small watershed approach with emphasis on event sampling. ?? 2008 Elsevier Ltd. All rights reserved.

  9. Sleep Quality Improvement During Cognitive Behavioral Therapy for Anxiety Disorders.

    Science.gov (United States)

    Ramsawh, Holly J; Bomyea, Jessica; Stein, Murray B; Cissell, Shadha H; Lang, Ariel J

    2016-01-01

    Despite the ubiquity of sleep complaints among individuals with anxiety disorders, few prior studies have examined whether sleep quality improves during anxiety treatment. The current study examined pre- to posttreatment sleep quality improvement during cognitive behavioral therapy (CBT) for panic disorder (PD; n = 26) or generalized anxiety disorder (GAD; n = 24). Among sleep quality indices, only global sleep quality and sleep latency improved significantly (but modestly) during CBT. Sleep quality improvement was greater for treatment responders, but did not vary by diagnosis. Additionally, poor baseline sleep quality was independently associated with worse anxiety treatment outcome, as measured by higher intolerance of uncertainty. Additional intervention targeting sleep prior to or during CBT for anxiety may be beneficial for poor sleepers.

  10. Motivation and affect in REM sleep and the mentation reporting process.

    Science.gov (United States)

    Smith, Mark R; Antrobus, John S; Gordon, Evelyn; Tucker, Matthew A; Hirota, Yasutaka; Wamsley, Erin J; Ross, Lars; Doan, Tieu; Chaklader, Annie; Emery, Rebecca N

    2004-09-01

    Although the emotional and motivational characteristics of dreaming have figured prominently in folk and psychoanalytic conceptions of dream production, emotions have rarely been systematically studied, and motivation, never. Because emotions during sleep lack the somatic components of waking emotions, and they change as the sleeper awakens, their properties are difficult to assess. Recent evidence of limbic system activation during REM sleep suggests a basis in brain architecture for the interaction of motivational and cognitive properties in dreaming. Motivational and emotional content in REM and NREM laboratory mentation reports from 25 participants were compared. Motivational and emotional content was significantly greater in REM than NREM sleep, even after controlling for the greater word count of REM reports.

  11. Experimental and theoretical study of the operation of longitudinal sidewalls in reinforced concrete superstructures

    Science.gov (United States)

    Bokarev, Sergey; Efimov, Stefan

    2017-11-01

    In the present article, we report results of a laboratory experimental study of reinforced-concrete superstructure fragments with extended longitudinal boxing sidewalls. The study included laboratory tests and numerical experiments performed using a finite element model of fragments generated in specialized simulation software. The distribution of horizontal pressures over the height of longitudinal boxing sidewalls, the dependence of the bending moment in the root section of the sidewalls on the ballast-bed thickness under sleepers, and some other characteristics were examined. The results of the experimental and theoretical study have shown a good convergence of obtained data to each other and to the data obtained by an improved engineering calculation procedure proposed by the present authors.

  12. Pillow use: the behaviour of cervical pain, sleep quality and pillow comfort in side sleepers.

    Science.gov (United States)

    Gordon, Susan J; Grimmer-Somers, Karen; Trott, Patricia

    2009-12-01

    A random allocation single blind block design pillow field study was undertaken to investigate the behaviour of cervico-thoracic spine pain in relation to pillow use. Participants (N=106) who reported preference for side sleep position with one pillow were recruited via a telephone survey and newspaper advertisement. They recorded sleep quality and pillow comfort ratings, frequency of retiring and waking cervical pain and duration of waking cervical pain while sleeping for a week on their usual pillow, polyester, foam, feather and rubber pillows of regular shape and a foam contour pillow. Analysis was undertaken comparing sleep quality, pillow comfort, waking and temporal cervical pain reports, between the usual pillow and the trial pillows, between pillows of differing content and foam pillows of differing shape. This study provides evidence to support recommendation of rubber pillows in the management of waking cervical pain, and to improve sleep quality and pillow comfort. The rubber pillow performed better than subjects' own pillow in most instances. Subjects' own pillow performed similarly to foam and polyester pillows, and there is no evidence that the use of a foam contour pillow has advantages over the regular shaped pillows. Feather pillows should not be recommended.

  13. Dysfunctional beliefs and attitudes about sleep among older adults with and without insomnia complaints.

    Science.gov (United States)

    Morin, C M; Stone, J; Trinkle, D; Mercer, J; Remsberg, S

    1993-09-01

    This study examined the beliefs and attitudes about sleep among 145 older adults. Ss were either chronic insomniacs (n = 74) or self-defined good sleepers (n = 71). They rated their level of agreement or disagreement (visual analog scale) with 28 statements tapping various beliefs, expectations, and attributions about several sleep-related themes. The results showed that insomniacs endorsed stronger beliefs about the negative consequences of insomnia, expressed more hopelessness about the fear of losing control of their sleep, and more helplessness about its unpredictability. These findings suggest that some beliefs and attitudes about sleep may be instrumental in perpetuating insomnia. The main clinical implication is that these cognitions should be identified and targeted for alteration in the management of late-life insomnia.

  14. The Sleeper and the Spindle de Neil Gaiman : quand les reines prennent leur destin en main

    Directory of Open Access Journals (Sweden)

    Stéphanie Schneider

    2016-12-01

    Full Text Available Dans le recueilintitulé "Rags and Bones: New Twists on Timeless Tales", chaque auteur choisissait un conte qui l’avait particulièrement touché (soit inspiré, émerveillé ou profondément agacé, le désossait et le reconstruisait à l’attention des jeunes lecteurs actuels. Ainsi, réécrit d’un point de vue contemporain, chacun des contes du recueil se propose, tout en rendant hommage aux textes sources, de soulever un débat particulier. Nous axerons le nôtre autour du destin des personnages féminins.

  15. Are better sleepers more engaged workers? A self-regulatory approach to sleep hygiene and work engagement.

    Science.gov (United States)

    Barber, Larissa; Grawitch, Matthew J; Munz, David C

    2013-10-01

    Previous research has emphasized facets of both the organizational environment and individual differences as predictors of work engagement. This study explored sleep hygiene as another important behavioural factor that may be related to work engagement. With a sample of 328 adult workers, we tested a multiple mediator model in which sleep hygiene predicts work engagement through one's appraisals of resource depletion stemming from demands (psychological strain) and general self-regulatory capacity (self-control). Results indicated that individuals who frequently engaged in poor sleep hygiene behaviours had lower self-regulatory capacity, experienced higher subjective depletion and were less engaged at work. Additionally, the path from poor sleep hygiene to decreased work engagement was attributed to perceptions of personal resources that are needed to exert self-regulatory energy at work. This is consistent with current self-regulatory theories suggesting that individuals have a limited amount of resources to allocate to demands and that the depletion of these resources can lead to stress and lower self-regulatory functioning in response to other demands. Specifically, poor sleep hygiene results in the loss of self-regulatory resources needed to be engaged in work tasks by impairing the after-work recovery process. Practical and research implications regarding sleep hygiene interventions for well-being and productivity improvement are discussed. Copyright © 2012 John Wiley & Sons, Ltd.

  16. Sleep quality among relatively younger patients with initial diagnosis of hypertension: dippers versus non-dippers.

    Science.gov (United States)

    Yilmaz, Mehmet Birhan; Yalta, Kenan; Turgut, Okan Onur; Yilmaz, Ahmet; Yucel, Oguzhan; Bektasoglu, Gokhan; Tandogan, Izzet

    2007-01-01

    Sleep is a basic physiological process. Normal sleep yields decrease in sympathetic activity, blood pressure (BP) and heart rate. Those, who do not have expected decrease in their BP are considered "non-dippers". We aimed to determine if there was any association between the non-dipping status and sleep quality, designed a cross-sectional study, and enrolled and evaluated the sleep quality of relatively young patients with an initial diagnosis of hypertension. Seventy-five consecutive patients, diagnosed to have stage 1 hypertension by their primary physicians, were referred to our study. Patients had newly diagnosed with stage 1 hypertension. Patients with a prior use of any anti-hypertensive medication were not included. Eligible patients underwent the Pittsburgh Sleep Quality Index (PSQI), which has an established role in evaluating sleep disturbances. All patients underwent ambulatory BP monitoring. There were 42 non-dipper patients (mean age = 47.5+/-11.9 years, 24 male/18 female), as a definition, 31 dipper hypertensive patients (mean age = 48.5+/-12.8 years, 21 male/10 female) and two with white coat hypertension. Daytime systolic and diastolic mean BPs were not significantly different between the two groups. Night-time mean systolic and diastolic BPs were significantly higher in non-dippers compared with dippers. PSQI scores, globally, were significantly higher in non-dippers compared with dippers. Total PSQI score was not correlated with body mass index. It was noticed that, individually, sleep quality, sleep efficiency and sleep disturbance scores were significantly higher in non-dippers. Being a poor sleeper in terms of high PSQI score (total score>5) was associated with 2.955-fold increased risk of being a non-dipper (95% confidence interval 1.127-7.747). We showed that the risk of having non-dipping hypertension, a risk factor for poor cardiovascular outcomes among hypertensive individuals, was tripled (odds ratios) among poor sleepers. We think that

  17. Insomnia Severity Index: psychometric properties with Chinese community-dwelling older people.

    Science.gov (United States)

    Yu, Doris S F

    2010-10-01

    This paper is a report of a study to evaluate the psychometric properties of the Chinese version of the Insomnia Severity Index. Despite the high prevalence of insomnia in older people and its detrimental impact on well-being and healthcare costs, this problem is almost always undetected and consequently under-treated. The Insomnia Severity Index is psychometrically sound in measuring perceived insomnia severity. However, it has had very limited application in non-White populations. An instrument validation study was carried out between October 2008 and April 2009. The Insomnia Severity Index was translated into Chinese using Brislin's model and administered to a convenience sample of 585 older Chinese people recruited from three community centres for elders. Other instruments were also administered, including the Chinese version of the Pittsburgh Sleep Quality Index and the Geriatric Depression Scale. Cronbach's alpha of the Chinese version of the Insomnia Severity Index was 0.81, with item-to-total correlations in the range of 0.34-0.67. Construct validity was supported by its moderate relationship with the Chinese Pittsburgh Sleep Quality Index and sleep efficiency. The Chinese version of the Insomnia Severity Index also indicated more severe level of insomnia in older people who reported depressed mood on the Geriatric Depression Scale. Discriminant validity was supported as the Chinese version of the Insomnia Severity Index could discriminate poorer sleepers from normal sleepers. Exploratory factor analysis identified a two-factor structure for the Chinese version of the Insomnia Severity Index in measuring the severity and impacts of insomnia on the Chinese older people. The Chinese version of the Insomnia Severity Index is a culturally-relevant and psychometrically-sound instrument for assessing severity and impact of insomnia in Chinese community-dwelling older people. Nurses can use this tool to assess older people's perceptions of insomnia. © 2010 The

  18. Postprandial thermogenesis and substrate oxidation are unaffected by sleep restriction

    Science.gov (United States)

    Shechter, Ari; Rising, Russell; Wolfe, Scott; Albu, Jeanine B.; St-Onge, Marie-Pierre

    2014-01-01

    Background/Objectives The extent to which alterations in energy expenditure (EE) in response to sleep restriction contribute to the short sleep-obesity relationship is not clearly defined. Short sleep may induce changes in resting metabolic rate (RMR), thermic effect of food (TEF), and postprandial substrate oxidation. Subjects/Methods Ten females (age and BMI: 22-43 y and 23.4-28 kg/m2) completed a randomized, crossover study assessing the effects of short (4 h/night) and habitual (8 h/night) sleep duration on fasting and postprandial RMR and respiratory quotient (RQ). Measurements were taken after 3 nights using whole-room indirect calorimetry. The TEF was assessed over a 6-h period following consumption of a high-fat liquid meal. Results Short vs. habitual sleep did not affect RMR (1.01 ± 0.05 and 0.97 ± 0.04 kcal/min; p=0.23). Fasting RQ was significantly lower after short vs. habitual sleep (0.84 ± 0.01 and 0.88 ± 0.01; p=0.028). Postprandial EE (short: 1.13 ± 0.04 and habitual: 1.10 ± 0.04, p=0.09) and RQ (short: 0.88 ± 0.01 and habitual: 0.88 ± 0.01, p=0.50) after the high-fat meal were not different between conditions. TEF was similar between conditions (0.24 ± 0.02 kcal/min in both; p=0.98), as was the ~6-h incremental area under the curve (1.16 ± 0.10 and 1.17 ± 0.09 kcal/min x 356 min after short and habitual sleep, respectively; p=0.92). Conclusions Current findings observed in non-obese healthy premenopausal women do not support the hypothesis that alterations in TEF and postprandial substrate oxidation are major contributors to the higher rate of obesity observed in short sleepers. In exploring a role of sleep duration on EE, research should focus on potential alterations in physical activity to explain the increased obesity risk in short sleepers. PMID:24352294

  19. Habitual short sleep impacts frontal switch mechanism in attention to novelty.

    Science.gov (United States)

    Gumenyuk, Valentina; Roth, Thomas; Korzyukov, Oleg; Jefferson, Catherine; Bowyer, Susan; Drake, Christopher L

    2011-12-01

    Reduced time in bed relative to biological sleep need is common. The impact of habitual short sleep on auditory attention has not been studied to date. In the current study, we utilized novelty oddball tasks to evaluate the effect of habitual short sleep on brain function underlying attention control processes measured by the mismatch negativity (MMN, index of pre-attentive stage), P3a (attention-dependent), and P3b (memory-dependent) event related brain potentials (ERPs). An extended time in bed in a separate study was used to evaluate the possible reversal of the impairments of these processes in habitual short sleepers. Ten self-defined short sleepers (total sleep time [TST] ≤ 6 h) and 9 normal-sleeping subjects with TST 7-8 h, participated. ERPs were recorded via a 64-channel EEG system. Two test conditions: "ignore" and "attend" were implemented. The ERPs were analyzed and compared between groups on the 2 task conditions and frontal/central/parietal electrodes by 3-factor ANOVA. Sleep diary data were compared between groups by t-test. Sleep was recorded by the Zeo sleep monitoring system for a week in both habitual and extended sleep conditions at home. The main findings of the present study show that short sleeping individuals had deficiency in activity of the MMN and P3a brain responses over frontal areas compared to normal-sleeping subjects. The P3b amplitude was increased over frontal areas and decreased over parietal with respect to the control group. Extension of time in bed for one week increased TST (from 5.7 h to 7.4 h), and concomitantly MMN amplitude increased from -0.1 μV up to -1.25 μV over frontal areas. Reduced time in bed is associated with deficiency of the neuronal process associated with change detection, which may recover after one week of sleep extension, whereas attention-dependent neural processes do not normalize after this period of time in habitually short sleeping individuals and may require longer recovery periods.

  20. Marginal overweight operating scenario for DOE's initiative I highway casks

    International Nuclear Information System (INIS)

    Hill, C.V.; Loud, G.C.; Heitzman, A.C.

    1993-01-01

    This paper assesses the potential transport of high-capacity Initiative I highway casks under development by the Office of Civilian Radioactive Waste Management (OCRWM) as permitted marginal overweight shipments that: exceed a gross vehicle weight (gvw) limit of 80,000, but weight less than 96,000 pounds; follow axle and axle group weight limits adopted by the Surface Transportation Assistance Act (STAA) of 1982; conform to dimensional restrictions to operate on most major highways; and comply with the Federal Bridge Formula. The marginal overweight tractor-trailer would operate in normal open-quotes over-the-roadclose quotes mode and comply with all laws and regulations. The vehicle would have a sleeper berth and two drivers - one to drive while the other provides escort and communications services and accumulates required off-duty time

  1. Numerical Modelling of the Dynamic Response of High-Speed Railway Bridges Considering Vehicle-Structure and Structure-Soil-Structure Interaction

    DEFF Research Database (Denmark)

    Bucinskas, Paulius; Agapii, L.; Sneideris, J.

    2015-01-01

    is idealized as a multi-degree-of-freedom system, modelled with two layers of spring-dashpot suspension systems. Coupling the vehicle system and railway track is realized through interaction forces between the wheels and the rail, where the irregularities of the track are implemented as a random stationary......The aim of this paper is the dynamic analysis of a multi-support bridge structure exposed to high-speed railway traffic. The proposed computational model has a unified approach for simultaneously accounting for the bridge structure response, soil response and forces induced by the vehicle....... The bridge structure is modelled in three dimensions based on the finite element method using two-noded three-dimensional beam elements. The track structure is composed of three layers: rail, sleepers and deck which are connected through spring-dashpot systems. The vehicle travelling along a bridge...

  2. Sleep patterns and disorders among university students in Lebanon.

    Science.gov (United States)

    Assaad, Shafika; Costanian, Christy; Haddad, Georges; Tannous, Fida

    2014-01-01

    Insufficient sleep is a significant public health issue with adverse medical consequences. Sleep disturbances are common among university students and have an effect on this group's overall health and functioning. The aim of this study was to investigate sleep habits and disorders in a population of university students across Lebanon. This was a cross-sectional study carried out in 2012 among 735 students aged 18-25 yrs. old, enrolled at six universities across Lebanon. The Pittsburg Sleep Quality Index (PSQI) was used to assess sleep quality and habits. Less than half of the total study population (47.3%) were good sleepers (PSQILebanon. This study suggests that sleep problems among Lebanese college students were common and such problems may interfere with daily performance. Findings from this study have important implications for programs intended to improve academic performance by targeting sleep habits of students.

  3. Psychometric Properties of the Consensus Sleep Diary in Those With Insomnia Disorder.

    Science.gov (United States)

    Maich, Kristin H G; Lachowski, Angela M; Carney, Colleen E

    2018-01-01

    The Consensus Sleep Diary (CSD) is a standardized, prospective tool for tracking nightly subjective sleep. The current study evaluated the validity and utility of the CSD, with consideration for challenges inherent to psychometric evaluation of diary measures. Results showed that the CSD indices differentiated good sleepers from those with insomnia and were associated with similar objective indices and a subjective insomnia severity measure. The ability to detect treatment improvements after cognitive behavior therapy for insomnia (CBT-I) was tested by comparing pre- and post-CBT-I CSD indices with a subjective rating of insomnia symptom severity. Improvement in insomnia symptom severity was significantly related to improvement on the CSD indices. Completion rate of the CSD amongst participants across all 14 days was 99.8%. These findings provide support for the validity, clinical utility, and usability of the CSD.

  4. Lifecycle Assessments of Railway Bridge Transitions Exposed to Extreme Climate Events

    Directory of Open Access Journals (Sweden)

    Sadudee Setsobhonkul

    2017-06-01

    Full Text Available Railway track components located at bridge transition zones or approach areas suffer from impact load and vibrations caused by abrupt changes in track stiffness on the bridge and the subgrade. The numerous strategies that can be used to mitigate these abrupt track stiffness changes rely on one of two concepts. The first concept is that of providing a gradual stiffness change, and the second is that of equalizing the track stiffness. A number of such mitigation methods have been developed and implemented over recent decades. Construction activities associated with these methods require various materials, processes, and uses of time, costs, and carbon emissions. In this study, eight of the most common techniques for railway bridge transition mitigation, including under ballast mats (UBMs, soft baseplates, under sleeper pads (USPs, rail pads, embankment treatments, transition slabs, ballast bonding, and wide sleepers, are compared. This study benchmarks the costs and carbon emissions of these eight mitigation techniques over the 50-year lifespan of a railway system subject to identical probabilities of four environmental scenarios: a control case, extremely high temperatures, extremely low temperatures, and flash flooding. This unprecedented study systemically investigates the effectiveness of the mitigation methods while considering the effects of 30 and 100 m bridge span lengths. Our results indicate that railway engineers should adopt different mitigation methods for different scenarios. The soft baseplate is the most appropriate method for a short-span bridge in the control case and the case of flash flooding, while ballast bonding is better for long-span railway bridges. Embankment treatment is recommended for both high- and low-extreme temperatures. However, its applicability is limited when the differential track stiffness is extremely high. Hence, alternatives that are 5–25% more expensive are proposed in parallel. The alternative

  5. Survey of maternal sleep practices in late pregnancy in a multi-ethnic sample in South Auckland, New Zealand.

    Science.gov (United States)

    Cronin, Robin S; Chelimo, Carol; Mitchell, Edwin A; Okesene-Gafa, Kara; Thompson, John M D; Taylor, Rennae S; Hutchison, B Lynne; McCowan, Lesley M E

    2017-06-17

    The Auckland Stillbirth study demonstrated a two-fold increased risk of late stillbirth for women who did not go to sleep on their left side. Two further studies have confirmed an increased risk of late stillbirth with supine sleep position. As sleep position is modifiable, we surveyed self-reported late pregnancy sleep position, knowledge about sleep position, and views about changing going-to-sleep position. Participants in this 2014 survey were pregnant women (n = 377) in their third trimester from South Auckland, New Zealand, a multi-ethnic and predominantly low socio-economic population. An ethnically-representative sample was obtained using random sampling. Multivariable logistic regression was performed to identify factors independently associated with non-left sided going-to-sleep position in late pregnancy. Respondents were 28 to 42 weeks' gestation. Reported going-to-sleep position in the last week was left side (30%), right side (22%), supine (3%), either side (39%) and other (6%). Two thirds (68%) reported they had received advice about sleep position. Non-left sleepers were asked if they would be able to change to their left side if it was better for their baby; 87% reported they would have little or no difficulty changing. Women who reported a non-left going-to-sleep position were more likely to be of Maori (aOR 2.64 95% CI 1.23-5.66) or Pacific (aOR 2.91 95% CI 1.46-5.78) ethnicity; had a lower body mass index (BMI) (aOR 0.93 95% CI 0.89-0.96); and were less likely to sleep on the left-hand side of the bed (aOR 3.29 95% CI 2.03-5.32). Maternal going-to-sleep position in the last week was side-lying in 91% of participants. The majority had received advice to sleep on their side or avoid supine sleep position. Sleeping on the left-hand side of the bed was associated with going-to-sleep on the left side. Most non-left sleepers reported their sleeping position could be modified to the left side suggesting a public health intervention about sleep

  6. Peruvians’ sleep duration: analysis of a population-based survey on adolescents and adults

    Science.gov (United States)

    Bernabé-Ortiz, Antonio; Miranda, J. Jaime; Rey de Castro, Jorge

    2014-01-01

    Background. Sleep duration, either short or long, has been associated with diseases such as obesity, type-2 diabetes and cardiovascular diseases. Characterizing the prevalence and patterns of sleep duration at the population-level, especially in resource-constrained settings, will provide informative evidence on a potentially modifiable risk factor. The aim of this study was to explore the patterns of sleep duration in the Peruvian adult and adolescent population, together with its socio-demographic profile. Material and Methods. A total of 12,424 subjects, mean age 35.8 years (SD ±17.7), 50.6% males, were included in the analysis. This is a cross-sectional study, secondary analysis of the Use of Time National Survey conducted in 2010. We used weighted means and proportions to describe sleep duration according to socio-demographic variables (area and region; sex; age; education attainment; asset index; martial and job status). We used Poisson regressions, taking into account the multistage sampling design of the survey, to calculate crude and adjusted prevalence ratios (PR) and 95% confidence intervals (95% CI). Main outcomes were short- (Peruvians slept 7.7 h (95% CI [7.4–8.0]) on weekdays and 8.0 h (95% CI [7.8–8.1]) during weekends. The proportions of short- and long-sleep, during weekdays, were 4.3% (95% CI [2.9%–6.3%]) and 22.4% (95% CI [14.9%–32.1%]), respectively. Regarding urban and rural areas, a much higher proportion of short-sleep was observed in the former (92.0% vs. 8.0%); both for weekdays and weekends. On the multivariable analysis, compared to regular-sleepers (≥ 6 to educational status, and 50% more likely to be currently employed. Similarly, relative to regular-sleep, long-sleepers were more likely to have a lower socioeconomic status as per educational attainment. Conclusions. In this nationally representative sample, the sociodemographic profile of short-sleep contrasts the long-sleep. These scenarios in Peru, as depicted by sleeping

  7. The Sleeper Effect of Intimate Partner Violence Exposure: Long-Term Consequences on Young Children's Aggressive Behavior

    Science.gov (United States)

    Holmes, Megan R.

    2013-01-01

    Background: Children who have been exposed to intimate partner violence (IPV) experience a wide variety of short-term social adjustment and emotional difficulties, including externalizing behavioral problems such as aggression. While children are affected by IPV at all ages, little is known about the long-term consequences of IPV exposure at…

  8. Stress Reactivity in Insomnia.

    Science.gov (United States)

    Gehrman, Philip R; Hall, Martica; Barilla, Holly; Buysse, Daniel; Perlis, Michael; Gooneratne, Nalaka; Ross, Richard J

    2016-01-01

    This study examined whether individuals with primary insomnia (PI) are more reactive to stress than good sleepers (GS). PI and GS (n = 20 per group), matched on gender and age, completed three nights of polysomnography. On the stress night, participants received a mild electric shock and were told they could receive additional shocks during the night. Saliva samples were obtained for analysis of cortisol and alpha amylase along with self-report and visual analog scales (VAS). There was very little evidence of increased stress on the stress night, compared to the baseline night. There was also no evidence of greater stress reactivity in the PI group for any sleep or for salivary measures. In the GS group, stress reactivity measured by VAS scales was positively associated with an increase in sleep latency in the experimental night on exploratory analyses. Individuals with PI did not show greater stress reactivity compared to GS.

  9. The effect of self-reported habitual sleep quality and sleep length on autobiographical memory.

    Science.gov (United States)

    Murre, Jaap M J; Kristo, Gert; Janssen, Steve M J

    2014-01-01

    A large number of studies have recently shown effects of sleep on memory consolidation. In this study the effects of the sleep quality and sleep length on the retention of autobiographical memories are examined, using an Internet-based diary technique (Kristo, Janssen, & Murre, 2009). Each of over 600 participants recorded one recent personal event and was contacted after a retention interval that ranged from 2 to 46 days. Recall of the content, time, and details of the event were scored and related to sleep quality and sleep length as measured with the Pittsburgh Sleep Quality Index. Hierarchical regression analyses indicated that poor sleep quality, but not short sleep length, was associated with significantly lower recall at the longer retention periods (30-46 days), but not at the shorter ones (2-15 days), although the difference in recall between good and poor sleepers was small.

  10. Banal no more: an essay on the film Hannah Arendt, with special reference to Eichmann and the Nazi killing groups.

    Science.gov (United States)

    Roth, Bennett

    2015-04-01

    This movie review and essay about the recent film Hannah Arendt by director Margarethe von Trotta seeks to examine Arendt's controversial term "banality of evil" as well as the nature of Arendt's misperception of Adolph Eichmann as thoughtless, and to situate Eichmann's personality within recent understandings of totalitarian group behavior and organizational killers. What emerges is that Arendt was unable to understand Eichmann's ruthless indifference to others as well as his attraction to being a Nazi and to organized mass killing. This paper examines Mann's (2005) formulation of different levels of functional attraction to totalitarian perpetrators, in which a racial morality is imposed and restrictions to eliminist violence are removed. Under such group conditions, violent "sleeper" needs emerge and are rationalized by political beliefs. In conclusion, the term "banality of evil" has little explanative value, while violent mass murder continues to this day as a totalitarian solution.

  11. Manifestations of Insomnia in Sleep Apnea: Implications for Screening and Treatment.

    Science.gov (United States)

    Bailes, Sally; Rizzo, Dorrie; Baltzan, Marc; Grad, Roland; Pavilanis, Alan; Creti, Laura; Fichten, Catherine S; Libman, Eva

    2016-01-01

    The aims of this study were to examine the presence, type, and severity of insomnia complaints in obstructive sleep apnea (OSA) patients and to assess the utility of the Sleep Symptom Checklist (SSC) for case identification in primary care. Participants were 88 OSA patients, 57 cognitive-behavioral therapy for insomnia (CBT-I) patients, and 14 healthy controls (Ctrl). Each completed a sleep questionnaire as well as the SSC, which includes insomnia, daytime functioning, psychological, and sleep disorder subscales. Results showed that OSA patients could be grouped according to 3 insomnia patterns: no insomnia (OSA), n = 21; insomnia (OSA-I), n = 30, with a subjective complaint and disrupted sleep; and noncomplaining poor sleepers (OSA-I-NC), n = 37. Comparisons among the OSA, CBT-I, and Ctrl groups demonstrate distinct profiles on the SSC subscales, indicating its potential utility for both case identification and treatment planning.

  12. Three-dimensional Finite Element Modelling of Composite Slabs for High Speed Rails

    Science.gov (United States)

    Mlilo, Nhlanganiso; Kaewunruen, Sakdirat

    2017-12-01

    Currently precast steel-concrete composite slabs are being considered on railway bridges as a viable alternative replacement for timber sleepers. However, due to their nature and the loading conditions, their behaviour is often complex. Present knowledge of the behaviour of precast steel-concrete composite slabs subjected to rail loading is limited. FEA is an important tool used to simulate real life behaviour and is widely accepted in many disciples of engineering as an alternative to experimental test methods, which are often costly and time consuming. This paper seeks to detail FEM of precast steel-concrete slabs subjected to standard in-service loading in high-speed rail with focus on the importance of accurately defining material properties, element type, mesh size, contacts, interactions and boundary conditions that will give results representative of real life behaviour. Initial finite element model show very good results, confirming the accuracy of the modelling procedure

  13. The choking game and YouTube: a dangerous combination.

    Science.gov (United States)

    Linkletter, Martha; Gordon, Kevin; Dooley, Joe

    2010-03-01

    To study postings of partial asphyxiation by adolescents on YouTube and to increase awareness of this dangerous activity as well as the value of YouTube as a research tool. Videos were searched on YouTube using many terms for recreational partial asphyxiation. Data were gathered on the participants and on the occurrence of hypoxic seizure. Sixty-five videos of the asphyxiation game were identified. Most (90%) participants were male. A variety of techniques were used. Hypoxic seizures were witnessed in 55% of videos, but occurred in 88% of videos that employed the "sleeper hold" technique. The videos were collectively viewed 173550 times on YouTube. YouTube has enabled millions of young people to watch videos of the "choking game" and other dangerous activities. Seeing videos may normalize the behavior among adolescents. Increased awareness of this activity may prevent some youths from participating and potentially harming themselves or others.

  14. Transient insomnia versus chronic insomnia: a comparison study of sleep-related psychological/behavioral characteristics.

    Science.gov (United States)

    Yang, Chien-Ming; Lin, Shih-Chun; Cheng, Chung-Ping

    2013-10-01

    Vulnerability to transient insomnia is regarded as a predisposing factor for chronic insomnia. However, most individuals with transient insomnia do not develop chronic insomnia. The current study investigated the differential contributing factors for these two conditions to further the understanding of this phenomenon. Chronic insomnia patients and normal sleepers with high and low vulnerability to transient insomnia completed measures of pre-sleep arousal, dysfunctional sleep beliefs, and sleep-related safety behaviors. Both cognitive and somatic pre-sleep arousals were identified as significant predictors for transient insomnia. Dysfunctional beliefs regarding worry about insomnia and cognitive arousal were predictors for chronic insomnia. Sleep-related safety behavior, although correlated with insomnia severity, was not a significant predictor for both conditions. Dysfunctional beliefs associated with worry and losing control over sleep are the most critical factors in differentiating chronic insomnia from transient insomnia. These factors should be addressed to help prevent individuals with high sleep vulnerability from developing chronic sleep disturbance. © 2013 Wiley Periodicals, Inc.

  15. Assessment of rail long-pitch corrugation

    Science.gov (United States)

    Valehrach, Jan; Guziur, Petr; Riha, Tomas; Plasek, Otto

    2017-09-01

    The paper focuses on defects of the running surface of the rail, namely the rail corrugation defect and specifically long-pitch corrugation in curves of small radii. These defects cause a shorter life of the rails, greater maintenance costs and increase the noise and vibration pollution. Therefore, it is very important to understand the formation and development of the imperfection of the rails. In the paper, various sections of railway tracks in the Czech Republic are listed, each of them completed with comparison of defect development, the particular track superstructure, rolling stock, axle load, traffic load etc. Based on performed measurements, defect development has been proved as different on sections with similar (or even same) parameters. The paper assumes that a train velocity is the significant circumstance for defect development rates. Assessment of track section with under sleeper pads, which are expected to be the one of the possible ways to suppress the corrugation defect development, is included in evaluation.

  16. Sleep quality and body mass index in college students: the role of sleep disturbances.

    Science.gov (United States)

    Vargas, Perla A; Flores, Melissa; Robles, Elias

    2014-01-01

    Obesity and its comorbidities have emerged as a leading public health concern. The aim of this study was to explore the relationship between body mass index (BMI) and sleep patterns, including duration and disturbances. A convenience sample of 515 college students completed an online survey consisting of the Pittsburgh Sleep Quality Index (PSQI), and self-reported height and weight to calculate BMI. Univariate and multivariate logistic regression analyses were performed using components of the PSQI as predictors of overweight (BMI ≥ 25). One-third of the participants had BMI ≥ 25, and 51% were poor-quality sleepers (PSQI > 5). Controlling for age and sex, only sleep disturbances were associated with overweight (odds ratio = 1.66, 95% confidence interval [1.08, 2.57]). Sleep disturbances, rather than sleep duration, predicted overweight among young adults; this is consistent with the most recent evidence in the literature. These findings support expanding the scope of wellness programs to promote healthy sleep among students.

  17. Role of sleep duration in the regulation of glucose metabolism and appetite.

    Science.gov (United States)

    Morselli, Lisa; Leproult, Rachel; Balbo, Marcella; Spiegel, Karine

    2010-10-01

    Sleep curtailment has become a common behavior in modern society. This review summarizes the current laboratory evidence indicating that sleep loss may contribute to the pathophysiology of diabetes mellitus and obesity. Experimentally induced sleep loss in healthy volunteers decreases insulin sensitivity without adequate compensation in beta-cell function, resulting in impaired glucose tolerance and increased diabetes risk. Lack of sleep also down-regulates the satiety hormone leptin, up-regulates the appetite-stimulating hormone ghrelin, and increases hunger and food intake. Taken together with the epidemiologic evidence for an association between short sleep and the prevalence or incidence of diabetes mellitus and/or obesity, these results support a role for reduced sleep duration in the current epidemic of these metabolic disorders. Screening for habitual sleep patterns in patients with "diabesity" is therefore of great importance. Studies are warranted to investigate the putative therapeutic impact of extending sleep in habitual short sleepers with metabolic disorders. Copyright © 2010 Elsevier Ltd. All rights reserved.

  18. Psychometric properties and clinical relevance of the adolescent sleep hygiene scale in Dutch adolescents.

    Science.gov (United States)

    de Bruin, Eduard J; van Kampen, Ris K A; van Kooten, Tamar; Meijer, Anne Marie

    2014-07-01

    This study investigated reliability, validity, and clinical relevance of the Adolescent Sleep Hygiene Scale (ASHS) in Dutch adolescents. The Dutch translation of the ASHS was administered to 186 normal-sleeping adolescents and 112 adolescents with insomnia. Their sleep variables were measured using sleep logs and questionnaires. From the insomnia group, scores were also obtained after six weeks of cognitive behavioral therapy for insomnia (n=58) or waiting list (n=22). The full scale of the ASHS had acceptable internal consistency. The results showed moderate to strong correlations of the ASHS (domains) with sleep quality, sleep duration and chronic sleep reduction. Furthermore, the Dutch ASHS was able to discriminate between normal sleepers and adolescents with insomnia, and scores of adolescents with insomnia improved after treatment. These findings confirm the importance of sleep hygiene in adolescent sleep, and contribute to the validity of the ASHS and its applicability in research and clinical practice. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Sleep Quality and Body Mass Index in College Students: The Role of Sleep Disturbances

    Science.gov (United States)

    Vargas, Perla A.; Flores, Melissa; Robles, Elias

    2014-01-01

    Objective Obesity and its comorbidities have emerged as a leading public health concern. Our aim was to explore the relationship between BMI and sleep patterns, including duration and disturbances. Methods A convenience sample of 515 college students completed an online survey consisting of the Pittsburgh Sleep Quality Index (PSQI), and self-reported height and weight to calculate Body Mass Index (BMI). Univariate and multivariate logistic regression analyses were performed using components of the PSQI as predictors of overweight (BMI ≥ 25). Results One-third of the participants had BMI ≥ 25, and 51% were poor-quality sleepers (PSQI > 5). Controlling for age and sex, only sleep disturbances were associated to overweight (OR=1.66, 95% CI: 1.08-2.57). Conclusions Sleep disturbances, rather than sleep duration predicted overweight among young adults; this is consistent with the most recent evidence in the literature. These findings support expanding the scope of wellness programs to promote healthy sleep among students. PMID:24933244

  20. Increased EEG sigma and beta power during NREM sleep in primary insomnia.

    Science.gov (United States)

    Spiegelhalder, Kai; Regen, Wolfram; Feige, Bernd; Holz, Johannes; Piosczyk, Hannah; Baglioni, Chiara; Riemann, Dieter; Nissen, Christoph

    2012-12-01

    The hyperarousal model of primary insomnia suggests that a deficit of attenuating arousal during sleep might cause the experience of non-restorative sleep. In the current study, we examined EEG spectral power values for standard frequency bands as indices of cortical arousal and sleep protecting mechanisms during sleep in 25 patients with primary insomnia and 29 good sleeper controls. Patients with primary insomnia demonstrated significantly elevated spectral power values in the EEG beta and sigma frequency band during NREM stage 2 sleep. No differences were observed in other frequency bands or during REM sleep. Based on prior studies suggesting that EEG beta activity represents a marker of cortical arousal and EEG sleep spindle (sigma) activity is an index of sleep protective mechanisms, our findings may provide further evidence for the concept that a simultaneous activation of wake-promoting and sleep-protecting neural activity patterns contributes to the experience of non-restorative sleep in primary insomnia. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. The borderlands of waking: Quantifying the transition from reflective thought to hallucination in sleep onset.

    Science.gov (United States)

    Speth, Clemens; Speth, Jana

    2016-04-01

    We lose waking consciousness spontaneously and regularly over the circadian cycle. It seems that every time we fall asleep, reflective thinking gradually gives way to our interactions with an imaginary, hallucinatory world that brings multimodal experiences in the absence of adequate external stimuli. The present study investigates this transition, proposing a new measure of hallucinatory states. Reflective thinking and motor imagery were quantified in 150 mentation reports provided by 16 participants after forced awakenings from different physiology-monitored time intervals after sleep onset. Cognitive agency analysis and motor agency analysis--which are objective (grammatical-semantic) tools derived from linguistic theories--show (i) a decrease in reflective thinking which sleepers would need to acknowledge the hallucinatory quality of their state, and (ii) an increase in motor imagery, indicating interactions with a hallucinatory world. By mapping these spontaneous changes in human consciousness onto physiology, we can in the long run explore the conditions of its decline, and possibilities for treatment. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Poor sleep quality and insufficient sleep of a collegiate student-athlete population.

    Science.gov (United States)

    Mah, Cheri D; Kezirian, Eric J; Marcello, Brandon M; Dement, William C

    2018-06-01

    Poor and inadequate sleep negatively impact cognitive and physical functioning and may also affect sports performance. The study aim is to examine sleep quality, sleep duration, and daytime sleepiness in collegiate student-athletes across a wide range of sports. Questionnaire. University setting. 628 athletes across 29 varsity teams at Stanford University. Athletes completed a questionnaire inquiring about sleep quality via a modified Pittsburgh Sleep Quality Index (PSQI), sleep duration, and daytime sleepiness via Epworth Sleepiness Scale. Sleep quality on campus and while traveling for competition was rated on a 10-point scale. Collegiate athletes were classified as poor sleepers (PSQI 5.38 ± 2.45), and 42.4% of athletes experience poor sleep quality (reporting PSQI global scores >5). Athletes reported lower sleep quality on campus than when traveling for competition (7.1 vs 7.6, Pquality, regularly obtain insufficient sleep, and commonly exhibit daytime sleepiness. Copyright © 2018 National Sleep Foundation. All rights reserved.

  3. Good and Bad Sleep in Childhood: A Questionnaire Survey amongst School Children in Southern Italy

    Directory of Open Access Journals (Sweden)

    Gianluca Ficca

    2011-01-01

    Full Text Available Despite its clinical importance, the issue of subjective sleep quality in children remains unexplored. Here we investigate, in school-aged children, the prevalence of bad sleep perception and its relationships with sleep habits and daytime functioning, to provide hints on its possible determinants. Subjective sleep perception, sleep habits, and daytime functioning were studied through a questionnaire survey in a sample of 482 children (6–12 yrs.. Being “bad sleeper” was reported by 6.9% of the sample. Compared to the “good sleepers”, these subjects displayed shorter sleep duration on schooldays, longer sleep latencies, and a more pronounced evening preference, beyond more frequent insufficient sleep. Though no differences emerged in sleepiness, bad sleepers showed higher impairments in daytime functioning, indicated by more frequent depressed mood and impulsivity. These distinctive features might be very important to precociously detect those children who are possibly more vulnerable to sleep disturbances and whose sleep-wake rhythms evolution should be paid particular attention thereafter.

  4. A model of BIS/BAS sensitivity, emotion regulation difficulties, and depression, anxiety, and stress symptoms in relation to sleep quality.

    Science.gov (United States)

    Markarian, Shaunt A; Pickett, Scott M; Deveson, Danielle F; Kanona, Brenda B

    2013-11-30

    Recent research has indicated that interactions between behavioral inhibition system (BIS)/behavioral activation system (BAS) sensitivity and emotion regulation (ER) difficulties increases risk for psychopathology. Considering sleep quality (SQ) has been linked to emotion regulation difficulties (ERD) and psychopathology, further investigation of a possible mechanism is needed. The current study examined associations between BIS/BAS sensitivity, ERD, and SQ to depression, anxiety, and stress symptoms in an undergraduate sample (n=459). Positive relationships between BIS sensitivity and both ERD and stress symptoms, and negative relationships between BAS-reward sensitivity and both ERD and depression symptoms were observed. Furthermore, ERD were positively related to depression, anxiety, and stress symptoms. Succeeding analyses revealed differential relationships between ERD and depression, anxiety, and stress symptoms among good quality and poor quality sleepers. The findings are discussed within the context of personality dimensions and self-regulatory mechanisms, along with implications for the treatment of depression, anxiety and sleep difficulties. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  5. Survey of chemical contaminants in the Hanalei River, Kaua'i, Hawai'i, 2001

    Science.gov (United States)

    Orazio, Carl E.; May, Thomas W.; Gale, Robert W.; Meadows, John C.; Brumbaugh, William G.; Echols, Kathy R.; Steiner, William W.M.; Berg, Carl J.

    2007-01-01

    The Hanalei River on the island of Kaua'i in Hawai'i was designated an American Heritage River in 1998, providing special attention to natural resource protection, economic revitalization, and historic and cultural preservation. Agricultural, urban, and tourism-related activities are potential sources of contamination within the Hanalei River watershed. The objective of this study was to measure certain persistent organic chemicals and elements in the Hanalei River.During a relatively low-flow period in December of 2001, samples of native Akupa sleeper fish (Eleotris sandwicensis), freshwater Asian clam (Corbicula fluminea), giant mud crab (Scylla serrata), surface water, and stream bed sediment were collected from a lower estuarine reach of the river near its mouth at Hanalei Bay and from an upper reach at the Hanalei National Wildlife Refuge. Samples were analyzed for residues of urban and agricultural chemicals including organochlorine pesticides, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, and elements (including mercury, lead, cadmium, arsenic, and selenium). Organic contaminants were extracted from the samples with solvent, enriched, and then analyzed by gas chromatographic analysis with electron capture or mass spectrometric detection. Samples were acid-digested for semi-quantitative analysis for elements by inductively-coupled plasma-mass spectrometry and for quantitative analysis by atomic absorption spectrophotometry.Concentrations of organochlorine pesticides, polycyclic aromatic hydrocarbons, and polychlorinated biphenyls in biota, surface water, and bed sediment sampled from the Hanalei River ranged from nondetectable to very low levels. Polychlorinated biphenyls were below detection in all samples. Dieldrin, the only compound detected in the water samples, was present at very low concentrations of 1-2 nanograms per liter. Akupa sleeper fish and giant mud crabs from the lower reach ranged from 1 to 5 nanograms per gram (wet weight

  6. Professional quality of life, wellness education, and coping strategies among emergency physicians.

    Science.gov (United States)

    El-Shafei, Dalia A; Abdelsalam, Amira E; Hammam, Rehab A M; Elgohary, Hayam

    2018-03-01

    Professional quality of life (ProQOL) is affected by and affects professional well-being and performance. The objectives of this study are to identify risk factors of ProQOL among EM physicians in Zagazig University hospitals (ZUHs), to detect the relationship between ProQOL and coping strategies, and to measure the implication of the Worksite Wellness Education (WWE) program on improving knowledge skills, ProQOL, and coping. An intervention study was conducted among 108 EM physicians at ZUHs through two stages: assessing ProQOL subscales (CS, BO, and STS) and coping strategies and conducting the WWE program. A pre-post-test design was used in the evaluation. CS was higher among the older age group, smokers, nighttime sleepers, and hobbies' practitioners. Coping strategies carried out by EM physicians to overcome stress and their ProQOL scores were improved significantly post program. ProQOL has multiple factors that affect it. Applying the WWE program will address this concept and may raise awareness about how to cope with work stressors.

  7. The effects of suppressing intrusive thoughts on dream content, dream distress and psychological parameters.

    Science.gov (United States)

    Kröner-Borowik, Tana; Gosch, Stefanie; Hansen, Kathrin; Borowik, Benjamin; Schredl, Michael; Steil, Regina

    2013-10-01

    Suppressing unwanted thoughts can lead to an increased occurrence of the suppressed thought in dreams. This is explainable by the ironic control theory, which theorizes why the suppression of thoughts might make them more persistent. The present study examined the influence of thought suppression on dream rebound, dream distress, general psychiatric symptomatology, depression, sleep quality and perceived stress. Thirty healthy participants (good sleepers) were investigated over a period of 1 week. Half were instructed to suppress an unwanted thought 5 min prior to sleep, whereas the other half were allowed to think of anything at all. Dream content was assessed through a dream diary. Independent raters assessed whether or not the dreams were related to the suppressed target thought. The results demonstrated increased target-related dreams and a tendency to have more distressing dreams in the suppression condition. Moreover, the data imply that thought suppression may lead to significantly increased general psychiatric symptomatology. No significant effects were found for the other secondary outcomes. © 2013 European Sleep Research Society.

  8. Reminders of Social Connection Can Attenuate Anthropomorphism.

    Science.gov (United States)

    Bartz, Jennifer A; Tchalova, Kristina; Fenerci, Can

    2016-12-01

    It is a fundamental human need to secure and sustain a sense of social belonging. Previous research has shown that individuals who are lonely are more likely than people who are not lonely to attribute humanlike traits (e.g., free will) to nonhuman agents (e.g., an alarm clock that makes people get up by moving away from the sleeper), presumably in an attempt to fulfill unmet needs for belongingness. We directly replicated the association between loneliness and anthropomorphism in a larger sample ( N = 178); furthermore, we showed that reminding people of a close, supportive relationship reduces their tendency to anthropomorphize. This finding provides support for the idea that the need for belonging has causal effects on anthropomorphism. Last, we showed that attachment anxiety-characterized by intense desire for and preoccupation with closeness, fear of abandonment, and hypervigilance to social cues-was a stronger predictor of anthropomorphism than loneliness was. This finding helps clarify the mechanisms underlying anthropomorphism and supports the idea that anthropomorphism is a motivated process reflecting the active search for potential sources of connection.

  9. Dynamic modelling of high speed ballasted railway trakcs: Analysis of the behaviour

    Energy Technology Data Exchange (ETDEWEB)

    Gallego, I.; Rivas, A.; Sanchez-Cambronero, S.; Lajara, J.

    2016-07-01

    The aim of the paper is to present a numerical model for a ballasted railway track that includes the dynamic effect of a moving train load and predicts the values of the vertical stiffness of the infrastructure. This model is therefore deemed to be a tool for the evaluation of the state of the track during service situations as well as a predictive model of the behaviour of the system. Consequently, it will be very useful when sizing the cross section of a new railway line is required.The main modelling tool is the finite element method. In regard to this, the application of damping elements to avoid the elastic wave reflection on the boundaries of the numerical domain will be studied. The proposed dynamic analysis consider the change in time of the value of the train load, but not the change in position along the tracks.In the end, a set of suggestions for the numerical model with moving loads will be summarize aiming for the mitigation of the unusual behaviour of the contact surface between the ballast and the sleepers. (Author)

  10. Advantage of using high strength self compacting concrete for precast product

    Science.gov (United States)

    Murdono, Ferryandy; Agustin, Winda; Soeprapto, Gambiro; Sunarso, Mukhlis

    2017-11-01

    According to the development in the world of construction, the need for precast concrete also increases. Now the day there are many products with narrow range reinforcement and difficult dimensions. The ordinary concrete is difficult to pour in a mold with narrow range reinforcement inside without vibrator because the concrete can't fill in the gaps between the bars. SCC (Self Compacting Concrete) is a concrete that precast concrete industry needs to. The using of SCC also supports the green construction through the cement reducing and reducing the use of vibrator that requires not less energy. This research is using EFNARC standard as a condition of admission SCC (filling ability, passing ability, segregation resistance), and performed well against the application of the product by the production of Railway Sleeper without using a vibrator. The results of this study, the LB-2 and LB-3 qualified as SCC and compressive strength is expected that greater than 70 MPa, as well as products quality, is equal to standard and can be mass produced with the efficiency of the price of concrete up to 11%.

  11. A study on the sleep patterns and problems of university business students in Hong Kong.

    Science.gov (United States)

    Tsui, Y Y; Wing, Y K

    2009-01-01

    To investigate sleep patterns and problems of university business students. Undergraduate Chinese business students in Hong Kong. Self-reported questionnaires were completed during class lectures and through online system. Of the 620 participating students (mean age 19.9 years), sleep duration was significantly shorter during weekdays (6.9 hours) than weekends (8.6 hours). Two thirds of students reported sleep deprivation. The following factors were associated with being a "poor sleeper" (Pittsburgh Sleep Quality Index > 5): attending early morning lectures (odds ratio [OR] = 1.90), living on-campus (OR = 1.89), Sleep Sufficiency Index less than 0.8 (OR = 2.55), sleep debt (differences of total time-in-bed between weekday and weekend > or = 75 minutes) (OR = 1.58), and minor psychiatric disturbances (OR = 2.82). Poor sleep quality and sleep deprivation were prevalent in university business students in Hong Kong, especially for those attending early morning lectures and living on-campus. Systemic education on the importance of sleep and stress and time management is needed for university students.

  12. How many sleep stages do we need for an efficient automatic insomnia diagnosis?

    Science.gov (United States)

    Hamida, Sana Tmar-Ben; Glos, Martin; Penzel, Thomas; Ahmed, Beena

    2016-08-01

    Tools used by clinicians to diagnose and treat insomnia typically include sleep diaries and questionnaires. Overnight polysomnography (PSG) recordings are used when the initial diagnosis is uncertain due to the presence of other sleep disorders or when the treatment, either behavioral or pharmacologic, is unsuccessful. However, the analysis and the scoring of PSG data are time-consuming. To simplify the diagnosis process, in this paper we have proposed an efficient insomnia detection algorithm based on a central single electroencephalographic (EEG) channel (C3) using only deep sleep. We also analyzed several spectral and statistical EEG features of good sleeper controls and subjects suffering from insomnia in different sleep stages to identify the features that offered the best discrimination between the two groups. Our proposed algorithm was evaluated using EEG recordings from 19 patients diagnosed with primary insomnia (11 females, 8 males) and 16 matched control subjects (11 females, 5 males). The sensitivity of our algorithm is 92%, the specificity is 89.9%, the Cohen's kappa is 0.81 and the agreement is 91%, indicating the effectiveness of our proposed method.

  13. A generalized theory of carcinogenesis due to chronodisruption.

    Science.gov (United States)

    Erren, Thomas C; Reiter, Russel J

    2008-12-01

    For two decades, research has been suggested and conducted into the causation and development of cancers in seemingly diverse and unrelated populations such as blind individuals, shift-workers, flight personnel, Arctic residents and subsets of sleepers. One common denominator of these investigations is "melatonin". Another common denominator is that all these studies implicitly pursued the validity of the so-called "melatonin hypothesis", of a corollary and of associated predictions which can be united in our proposed theory of "carcinogenesis due to chronodisruption". The new theory suggests that the various predictions investigated between 1987 and 2008 represent different aspects of the same problem. Indeed, abundant experimental evidence supports the notion that the final common cause of many cases of cancer may be what has been termed chronodisruption (CD), a relevant disturbance of the temporal organization or order of physiology, endocrinology, metabolism and behaviour. While melatonin as a key time messenger and time keeper can be a marker of CD, it is probably only partially related to the differential cancer occurrence apparent in individuals who chronically or frequently experience an excess or deficit of chronodisruption.

  14. Homeless who accessed a healthy living centre in Swansea, South Wales: an assessment of the impact of oral ill-health.

    Science.gov (United States)

    Richards, Wayne; Keauffling, Janet

    2009-07-01

    To quantify the way that oral diseases affect the lives of homeless and vulnerable people in Swansea, using the short-form Oral Health Impact Profile (OHIP-14). A convenience sample of people using the services of a healthy living centre for the homeless was surveyed using a questionnaire and the short-form OHIP-14. One hundred subjects were recruited to the study. The mean score for the OHIP-14 was 21.8 (SD 17.0). The most commonly reported impacts experienced were problems with toothache, discomfort, ability to relax, and feeling ashamed regarding the appearance of teeth. Of the different categories of homeless people, rough sleepers experienced higher levels of impact (P=0.004). Those having more than 20 teeth were more likely to experience lower levels of impact (P=0.001). The survey highlighted an increased prevalence of oral health impacts in this special needs group. In addition to physical factors, psychosocial factors must be considered, particularly with regard to appearance and psychological disability and discomfort, in the development of services.

  15. Sleep and Productivity Benefits of Digital Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial Conducted in the Workplace Environment.

    Science.gov (United States)

    Bostock, Sophie; Luik, Annemarie I; Espie, Colin A

    2016-07-01

    Evaluating digital cognitive behavioral therapy (dCBT) for insomnia in a workplace environment. Within a randomized controlled trial in a Fortune 500 company, we randomized 270 self-identified poor sleepers [180 M/90 F: mean age 33.6 years (23 to 56 years)] to dCBT (n = 135) or waiting list (WL, n = 135). dCBT comprised six online sessions delivered by an animated therapist. Major assessments were at baseline and posttreatment. Sleep Condition Indicator (SCI) scores were significantly higher for the dCBT group [interaction term: F (1,485) = 15.63, P < 0.0001], representing Cohen's d of 1.10 following dCBT (d = 0.34 for WL). On the Work Productivity and Impairment questionnaire, "presenteeism" demonstrated significant improvements following dCBT [F(1,485) = 10.99, P = 0.001: d = 0.64 for dCBT, d = 0.09 for WL]. Effects for "abseenteeism" failed to reach statistical significance (P = 0.101). dCBT is effective in improving sleep and work-based productivity in adults with insomnia.

  16. Stepping Stones Triple P: an RCT of a parenting program with parents of a child diagnosed with an autism spectrum disorder.

    Science.gov (United States)

    Whittingham, Koa; Sofronoff, Kate; Sheffield, Jeanie; Sanders, Matthew R

    2009-05-01

    Whilst the Triple P Positive Parenting Program has a large evidence base (Sanders, Clinical Child and Family Psychology Review 2:71-90, 1999; Sanders, Journal of Consulting and Clinical Psychology 68:624-640, 2000) and preliminary evidence indicates that Stepping Stones Triple P is also efficacious (Roberts, Journal of Clinical Child and Adolescent Psychology, 35(2):180-193, 2006), to date Stepping Stones has not been evaluated with the ASD population. Fifty-nine families with a child with ASD aged between 2 and 9 participated in this randomized controlled trial. The results demonstrate significant improvements in parental reports of child behaviour and parenting styles with the treatment effects for child behaviour, parental over reactivity and parental verbosity being maintained at follow-up 6 months later. Further, the results suggest significant improvements in parental satisfaction and conflict about parenting as well as a sleeper effect for parental efficacy. The results indicate that Stepping Stones Triple P is a promising intervention for parents of children with ASD. Limitations and future research are also addressed.

  17. Distributed support modelling for vertical track dynamic analysis

    Science.gov (United States)

    Blanco, B.; Alonso, A.; Kari, L.; Gil-Negrete, N.; Giménez, J. G.

    2018-04-01

    The finite length nature of rail-pad supports is characterised by a Timoshenko beam element formulation over an elastic foundation, giving rise to the distributed support element. The new element is integrated into a vertical track model, which is solved in frequency and time domain. The developed formulation is obtained by solving the governing equations of a Timoshenko beam for this particular case. The interaction between sleeper and rail via the elastic connection is considered in an analytical, compact and efficient way. The modelling technique results in realistic amplitudes of the 'pinned-pinned' vibration mode and, additionally, it leads to a smooth evolution of the contact force temporal response and to reduced amplitudes of the rail vertical oscillation, as compared to the results from concentrated support models. Simulations are performed for both parametric and sinusoidal roughness excitation. The model of support proposed here is compared with a previous finite length model developed by other authors, coming to the conclusion that the proposed model gives accurate results at a reduced computational cost.

  18. A psychological treatment programme for traumatised ex military personnel in the UK

    Directory of Open Access Journals (Sweden)

    Beatriz Sánchez España

    2008-12-01

    Full Text Available A large proportion of homeless people in the UK are former members of the armed services and suffer from a mental illness. In fact, homelessness itself can be considered a symptom or manifestation of other underlying psychological difficulties. For these reasons Community Housing and Therapy (CHT considers that providing psychological therapies to treat the homeless population is a more effective way of tackling the problem of homelessness, as it addresses the roots of the problem. This approach is one which is beginning to be recognised by leading agencies in the field. At the same time, the provision of psychological therapies for symptoms such as depression and anxiety has become accepted through the Department of Health’s (DoH Increased Access to Psychological Therapies ( IAPT initiative. Depression is the most common psychiatric disorder that homeless people suffer and it is well documented that psychological treatments for depression can be extremely effective. As well as approaching homelessness from the angle of psychological therapies, CHT in its work with the ex-service community has become increasingly aware that there are a large number of non statutory homeless that do not get the same attention as rough sleepers.

  19. The important role of sleep in metabolism.

    Science.gov (United States)

    Copinschi, Georges; Leproult, Rachel; Spiegel, Karine

    2014-01-01

    Both reduction in total sleep duration with slow-wave sleep (SWS) largely preserved and alterations of sleep quality (especially marked reduction of SWS) with preservation of total sleep duration are associated with insulin resistance without compensatory increase in insulin secretion, resulting in impaired glucose tolerance and increased risk of type 2 diabetes. When performed under rigorously controlled conditions of energy intake and physical activity, sleep restriction is also associated with a decrease in circulating levels of leptin (an anorexigenic hormone) and an increase in circulating levels of ghrelin (an orexigenic hormone), hunger and appetite. Furthermore, sleep restriction is also associated with a stimulation of brain regions sensitive to food stimuli, indicating that sleep loss may lead to obesity through the selection of high-calorie food. There is also evidence that sleep restriction could provide a permissive environment for the activation of genes that promote obesity. Indeed, the heritability of body mass index is increased in short sleepers. Thus, chronic sleep curtailment, which is on the rise in modern society, including in children, is likely to contribute to the current epidemics of type 2 diabetes and obesity. © 2014 S. Karger AG, Basel.

  20. Chemical and isotopic evolution of a layered eastern U.S. snowpack and its relation to stream-water composition

    Science.gov (United States)

    Shanley, J.B.; Kendall, C.; Albert, M.R.; Hardy, J.P.

    1995-01-01

    The chemical, isotopic, and morphologic evolution of a layered snowpack was investigated during the winter of 1993-94 at Sleepers River Research Watershed in Danville, Vermont. The snowpack was monitored at two small basins: a forested basin at 525 m elevation, and an agricultural basin at 292 m elevation. At each site, the snowpack morphology was characterized and individual layers were sampled seven times during the season. Nitrate and 8d18O profiles in the snowpack remained relatively stable until peak accumulation in mid-March, except near the snow surface, where rain-on-snow events caused water and nitrate movement down to impeding ice layers. Subsequently, water and nitrate moved more readily through the ripening snowpack. As the snowpack evolved, combined processes of preferential ion elution, isotopic fractionation, and infiltration of isotopically heavy rainfall caused the pack to become depleted in solutes and isotopically enriched. The release of nitrate and isotopically depleted water was reflected in patterns of nitrate concentrations and ??18O of meltwater and stream water. Results supported data from the previous year which suggested that streamflow in the forested basin during snowmelt was dominated by groundwater discharge.

  1. Otolith microchemistry of tropical diadromous fishes: spatial and migratory dynamics

    Science.gov (United States)

    Smith, William E.; Kwak, Thomas J.

    2014-01-01

    Otolith microchemistry was applied to quantify migratory variation and the proportion of native Caribbean stream fishes that undergo full or partial marine migration. Strontium and barium water chemistry in four Puerto Rico, U.S.A., rivers was clearly related to a salinity gradient; however, variation in water barium, and thus fish otoliths, was also dependent on river basin. Strontium was the most accurate index of longitudinal migration in tropical diadromous fish otoliths. Among the four species examined, bigmouth sleeper Gobiomorus dormitor, mountain mullet Agonostomus monticola, sirajo goby Sicydium spp. and river goby Awaous banana, most individuals were fully amphidromous, but 9-12% were semi-amphidromous as recruits, having never experienced marine or estuarine conditions in early life stages and showing no evidence of marine elemental signatures in their otolith core. Populations of one species, G. dormitor, may have contained a small contingent of semi-amphidromous adults, migratory individuals that periodically occupied marine or estuarine habitats (4%); however, adult migratory elemental signatures may have been confounded with those related to diet and physiology. These findings indicate the plasticity of migratory strategies of tropical diadromous fishes, which may be more variable than simple categorization might suggest.

  2. DNA barcoding for biosecurity: case studies from the UK plant protection program.

    Science.gov (United States)

    Hodgetts, Jennifer; Ostojá-Starzewski, Jozef C; Prior, Thomas; Lawson, Rebecca; Hall, Jayne; Boonham, Neil

    2016-11-01

    Since its conception, DNA barcoding has seen a rapid uptake within the research community. Nevertheless, as with many new scientific tools, progression towards the point of routine deployment within diagnostic laboratories has been slow. In this paper, we discuss the application of DNA barcoding in the Defra plant health diagnostic laboratories, where DNA barcoding is used primarily for the identification of invertebrate pests. We present a series of case studies that demonstrate the successful application of DNA barcoding but also reveal some potential limitations to expanded use. The regulated plant pest, Bursephalenchus xylophilus, and one of its vectors, Monochamus alternatus, were found in dining chairs. Some traded wood products are potentially high risk, allowing the movement of longhorn beetles; Trichoferus campestris, Leptura quadrifasciata, and Trichoferus holosericeus were found in a wooden cutlery tray, a railway sleeper, and a dining chair, respectively. An outbreak of Meloidogyne fallax was identified in Allium ampeloprasum and in three weed species. Reference sequences for UK native psyllids were generated to enable the development of rapid diagnostics to be used for monitoring following the release of Aphalara itadori as a biological control agent for Fallopia japonica.

  3. Self-reported sleep duration and weight-control strategies among U.S. high school students.

    Science.gov (United States)

    Wheaton, Anne G; Perry, Geraldine S; Chapman, Daniel P; Croft, Janet B

    2013-08-01

    To determine if self-reported sleep duration was associated with weight-control behaviors among US high school students. National Youth Risk Behavior Survey. United States, 2007. US high school students (N = 12,087). Students were asked if they had engaged in several weight-control behaviors during the 30 days before the survey to lose or maintain weight. Self-reported sleep duration categories included very short (≤ 5 h), short (6 or 7 h), referent moderate (8 or 9 h), and long (≥ 10 h). Sex-specific logistic regression analyses with race/ethnicity, grade, and body mass index category as covariates were conducted using SUDAAN to account for complex study design. Approximately half the students reported short sleep duration (51.8% of males and 54.3% of females), whereas very short sleep durations were reported by another 14.8% of males and 16.9% of females. Among males, very short sleepers were significantly (P sleep duration was associated with dieting and three unhealthy weight-control behaviors in this population. If our findings are confirmed, intervention studies should be conducted to examine the effect of educational interventions.

  4. Sleep quality of German soldiers before, during and after deployment in Afghanistan-a prospective study.

    Science.gov (United States)

    Danker-Hopfe, Heidi; Sauter, Cornelia; Kowalski, Jens T; Kropp, Stefan; Ströhle, Andreas; Wesemann, Ulrich; Zimmermann, Peter L

    2017-06-01

    In this prospective study, subjective sleep quality and excessive daytime sleepiness prior to, during and after deployment of German soldiers in Afghanistan were examined. Sleep quality (Pittsburgh Sleep Quality Index; PSQI) and daytime sleepiness (Epworth Sleepiness Scale; ESS) were assessed in 118 soldiers of the German army, who were deployed in Afghanistan for 6 months (deployment group: DG) and in 146 soldiers of a non-deployed control group (CG) at baseline. Results of the longitudinal analysis are reported, based on assessments conducted prior to, during the deployment and afterwards in the DG, and in the CG in parallel. Sleep quality and daytime sleepiness in the DG were already impaired during the predeployment training phase and remained at that level during the deployment phase, which clearly indicates the need for more attention on sleep in young soldiers, already at this early stage. The percentage of impaired sleepers decreased significantly after deployment. Programmes to teach techniques to improve sleep and reduce stress should be implemented prior to deployment to reduce sleep difficulties and excessive daytime sleepiness and subsequent psychiatric disorders. © 2017 European Sleep Research Society.

  5. Sleep-wake patterns in patients with cirrhosis: all you need to know on a single sheet. A simple sleep questionnaire for clinical use.

    Science.gov (United States)

    Montagnese, Sara; Middleton, Benita; Skene, Debra J; Morgan, Marsha Y

    2009-10-01

    Sleep-wake abnormalities are common in patients with cirrhosis but their evaluation is time consuming and laborious. The aim of this study was to assess the validity of a simple Sleep Timing and Sleep Quality Screening questionnaire (STSQS) against an established sleep quality questionnaire and daily sleep diaries. The study population comprised 87 patients with cirrhosis and 19 healthy volunteers. All participants completed the STSQS (sleep quality score range 1-9) and the Pittsburgh Sleep Quality Index (PSQI; total score range: 0-21; scores >5 identify 'poor' sleepers); a subgroup of 35 patients and 12 healthy volunteers also kept daily sleep diaries for 2 weeks. Patients slept significantly less well than the healthy volunteers (total PSQI score: 8.4+/-4.9 vs. 4.6+/-2.5, p4: sensitivity 75%, specificity 93%; patients: STSQS sleep quality >3: sensitivity 83%, specificity 70%). The STSQS provided estimates of habitual sleep timing variables which did not significantly differ from the average data recorded in the sleep diaries, although more variability was observed in the patients. The STSQS provides acceptable estimates of sleep quality and sleep timing and could be used to identify patients with cirrhosis whose sleep behaviour might require further assessment.

  6. Late Sleeping Affects Sleep Duration and Body Mass Index in Adolescents

    Directory of Open Access Journals (Sweden)

    Rajesh G.Kathrotia1,

    2010-03-01

    Full Text Available During adolescence, there is a tendency to sleep late andsleep less because of altered psychosocial and life-stylechanges. Recent studies have demonstrated the link betweensleeping less and gaining weight in children, adolescents, andadults. We studied the effect of late sleeping and sleepingless on body mass index (BMI in medical college freshmen.All participants were adolescents (104 male and 38 femaleadolescents, mean age 17.77±0.79 years. After obtaininginformed consent, they filled out a questionnaire about theirsleeping habits. Height and weight were measured after abrief history taking and clinical examination. BMI increasedsignificantly with decrease in total sleep duration and withdelayed bedtime. Late sleeping individuals (after midnighthad significantly less sleep duration (6.78 hours v 7.74 hours,P<0.001, more day time sleepiness (85.2% v 69.3%,P=0.033 and more gap between dinner time and going tosleep (234.16 min v 155.45 min, P<0.001. Increased BMI inlate sleepers may be explained by low physical activity duringthe day caused by excess sleepiness and increased calorieintake with a gap of 5-6 hours between dinner and sleep.Sleep habits of late sleeping and sleeping less contribute toincrease BMI in adolescents.

  7. Influence of increasing amount of recycled concrete powder on mechanical properties of cement paste

    Science.gov (United States)

    Topič, Jaroslav; Prošek, Zdeněk; Plachý, Tomáš

    2017-09-01

    This paper deals with using fine recycled concrete powder in cement composites as micro-filler and partial cement replacement. Binder properties of recycled concrete powder are given by exposed non-hydrated cement grains, which can hydrate again and in small amount replace cement or improve some mechanical properties. Concrete powder used in the experiments was obtained from old railway sleepers. Infrastructure offer more sources of old concrete and they can be recycled directly on building site and used again. Experimental part of this paper focuses on influence of increasing amount of concrete powder on mechanical properties of cement paste. Bulk density, shrinkage, dynamic Young’s modulus, compression and flexural strength are observed during research. This will help to determine limiting amount of concrete powder when decrease of mechanical properties outweighs the benefits of cement replacement. The shrinkage, dynamic Young’s modulus and flexural strength of samples with 20 to 30 wt. % of concrete powder are comparable with reference cement paste or even better. Negative effect of concrete powder mainly influenced the compression strength. Only a 10 % cement replacement reduced compression strength by about 25 % and further decrease was almost linear.

  8. Factors related to self-reported social anxiety symptoms among incoming university students.

    Science.gov (United States)

    Cheng, Shu Hui; Sun, Zih-Jie; Lee, I Hui; Lee, Chih-Ting; Chen, Kao Chin; Tsai, Chung Hung; Yang, Yen Kuang; Yang, Yi Ching

    2017-08-01

    The aim of this study was to explore the lifestyle/social, personality trait and mental factors among incoming university students with higher self-reported social anxiety symptoms (SAS). A total of 5126 incoming university students were recruited. The test battery included a self-administered questionnaire that examined personal lifestyle, the Measurement of Support Functions, the Chinese Internet Addiction Scale-Revision, the Organizational Citizenship Behaviour Scale, the Social Phobia Inventory, the suicide ideation from the Brief Symptoms Rating Scale and the Pittsburgh Sleep Questionnaire. SAS (23.7%) were prevalent. Using logistic regression analysis, we found that the significant predictors of higher levels of SAS were being an undergraduate student and a non-smoker, having lower Measurement of Support Functions score (poorer social support), having higher Chinese Internet Addiction Scale-Revision score (Internet addiction), having lower Organizational Citizenship Behaviour Scale score (less altruistic behaviour), having suicide ideation and having higher Pittsburgh Sleep Questionnaire score (poorer sleeper). Given the high prevalence of SAS among university students, it is necessary to build a better strategy to detect students with potential social anxiety-related problems/disorders or other mental problems early on. © 2015 Wiley Publishing Asia Pty Ltd.

  9. Climate change and biological invasions: evidence, expectations, and response options.

    Science.gov (United States)

    Hulme, Philip E

    2017-08-01

    A changing climate may directly or indirectly influence biological invasions by altering the likelihood of introduction or establishment, as well as modifying the geographic range, environmental impacts, economic costs or management of alien species. A comprehensive assessment of empirical and theoretical evidence identified how each of these processes is likely to be shaped by climate change for alien plants, animals and pathogens in terrestrial, freshwater and marine environments of Great Britain. The strongest contemporary evidence for the potential role of climate change in the establishment of new alien species is for terrestrial arthropods, as a result of their ectothermic physiology, often high dispersal rate and their strong association with trade as well as commensal relationships with human environments. By contrast, there is little empirical support for higher temperatures increasing the rate of alien plant establishment due to the stronger effects of residence time and propagule pressure. The magnitude of any direct climate effect on the number of new alien species will be small relative to human-assisted introductions driven by socioeconomic factors. Casual alien species (sleepers) whose population persistence is limited by climate are expected to exhibit greater rates of establishment under climate change assuming that propagule pressure remains at least at current levels. Surveillance and management targeting sleeper pests and diseases may be the most cost-effective option to reduce future impacts under climate change. Most established alien species will increase their distribution range in Great Britain over the next century. However, such range increases are very likely be the result of natural expansion of populations that have yet to reach equilibrium with their environment, rather than a direct consequence of climate change. To assess the potential realised range of alien species will require a spatially explicit approach that not only

  10. Exploring the associations shared by mood, pain-related attention and pain outcomes related to sleep disturbance in a chronic pain sample.

    Science.gov (United States)

    Harrison, Lee; Wilson, Sue; Heron, Jon; Stannard, Catherine; Munafò, Marcus R

    2016-05-01

    Sleep disturbance in chronic pain is common, occurring in two-thirds of patients. There is a complex relationship between chronic pain and sleep; pain can disrupt sleep and poor sleep can exaggerate pain intensity. This may have an impact on both depressive symptoms and attention to pain. This study aims to evaluate the relationship between chronic pain and sleep, and the role of mood and attention. Chronic pain patients, recruited from a secondary care outpatient clinic, completed self-report measures of pain, sleep, depressive symptoms and attention to pain. Hierarchical regression and structural equation modelling were used to explore the relationships between these measures. Participants (n = 221) were aged between 20 and 84 (mean = 52) years. The majority of participants were found to be 'poor sleepers' (86%) with increased pain severity, depressive symptoms and attention to pain. Both analytical approaches indicated that sleep disturbance is indirectly associated with increased pain severity Instead the relationship shared by sleep disturbance and pain severity was further associated with depressive symptoms and attention to pain. Our results indicate that sleep disturbance may contribute to clinical pain severity indirectly though changes in mood and attention. Prospective studies exploring lagged associations between these constructs could have critical information relevant to the treatment of chronic pain.

  11. Massive contamination of Exophiala dermatitidis and E. phaeomuriformis in railway stations in subtropical Turkey.

    Science.gov (United States)

    Döğen, Aylin; Kaplan, Engin; Ilkit, Macit; de Hoog, G Sybren

    2013-06-01

    In order to reveal the source of contamination of opportunistic fungi, their natural habitat has to be understood. Black yeast-like fungi are abundant in man-made environments, particularly in those that are rich in toxic hydrocarbons such as railway ties. In this study, we investigated the presence of black fungi on creosote-treated oak railway ties and concrete sleepers stained with petroleum oil. Samples were collected at two central stations in Turkish cities, Mersin and Adana, and from Tarsus town station located between these two. The sample locations had subtropical climates. A total of 570 railway samples, including 320 from oak and 250 from concrete, were collected. Cotton swabs moistened with sterile physiological saline were applied to the ties and inoculated onto malt extract agar followed by incubation at 37 °C. Overall, we recovered 97 black yeast-like fungi (17.0 % positive). Sixty-three fungi (19.7 %) were collected from creosote-treated oak, whereas 34 isolates (13.6 %) were derived from concrete; the difference was significant (P = 0.05). Identification using rDNA internal transcribed spacer revealed Exophiala dermatitidis (57.7 %) and Exophiala phaeomuriformis (42.3 %). This study suggested that hydrocarbons enrich these opportunistic black yeasts. An eventual health risk is discussed.

  12. Sleep duration and its association with demographics, lifestyle factors, poor mental health and chronic diseases in older Chinese adults.

    Science.gov (United States)

    Wang, Shibin; Wu, Yanhua; Ungvari, Gabor S; Ng, Chee H; Forester, Brent P; Gatchel, Jennifer R; Chiu, Helen F K; Kou, Changgui; Fu, Yingli; Qi, Yue; Yu, Yaqin; Li, Bo; Xiang, Yu-Tao

    2017-11-01

    This study investigated the total sleep time (TST) and its associated factors in an older Chinese adult population. Multistage stratified cluster sampling was used in this cross-sectional study. A total of 4,115 older adults aged 60 to 79 years were selected and interviewed. Sleep duration was classified as short (8h per day) and medium sleep (7-8h per day). The total mean sleep time was 6.86±1.75h. Short and long sleepers accounted for 45.2% and 14.8% of the sample, respectively. Multivariate logistic regression analysis revealed that inadequate fruit intake and poor mental health were positively associated with short sleep, and married/cohabitation status and living in rural areas was negatively associated with short sleep. In addition, aged 75-79 years old, inadequate fruit intake, poor mental health and multi-morbidity were positively associated with long sleep. Ischemic heart disease, COPD and chronic gastroenteritis/peptic ulcer were positively associated with short sleep duration, while hyperlipidemia, hypertension, cerebrovascular diseases, and urolithiasis were positively associated with long sleep duration. Given the high frequency of aberrant sleep duration and its negative health impact, health professionals should pay more attention to sleep patterns in older people. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Sleep as a component of the performance triad: the importance of sleep in a military population.

    Science.gov (United States)

    Lentino, Cynthia V; Purvis, Dianna L; Murphy, Kaitlin J; Deuster, Patricia A

    2013-01-01

    Sleep habits among military populations are problematic. Poor sleep hygiene occurs in parallel with the global increase in obesity and metabolic syndrome and contributes to a decrease in performance. The extent of sleep issues needs to be quantified to provide feedback for optimizing warfighter performance and readiness. This study assessed various health behaviors and habits of US Army Soldiers and their relationship with poor sleep quality by introducing a set of new questions into the Comprehensive Soldier and Family Fitness (CSF2) Global Assessment Tool (GAT). Subjects included 14,148 US Army Active, Reserve, and National Guard members (83.4% male) who completed the GAT, a self-report questionnaire that measures 4 fitness dimensions: social, family, emotional, and spiritual. Approximately 60 new questions, including ones on sleep quality, within the fifth CSF2 dimension (physical) were also answered. A sleep score was calculated from 2 questions validated in the Pittsburgh Insomnia Rating Scale (0 to 6). Poor sleepers (5-6) were significantly (Psleep quality in a group of military personnel and indicated significant associations between quality of sleep and physical performance, nutritional habits, measures of obesity, lifestyle behaviors and measures of psychosocial status. Targeted educational interventions and resources are needed to improve sleep patterns based on behaviors that can be most easily modified.

  14. Transition into daylight saving time influences the fragmentation of the rest-activity cycle

    Directory of Open Access Journals (Sweden)

    Tuulio-Henriksson Annamari

    2006-01-01

    Full Text Available Abstract Background Daylight saving time is widely adopted. Little is known about its influence on the daily rest-activity cycles. We decided to explore the effects of transition into daylight saving time on the circadian rhythm of activity. Methods We monitored the rest-activity cycles with the use of wrist-worn accelerometer on a sample of ten healthy adults for ten days around the transition into summer time. Identical protocols were carried out on the same individuals in two consecutive years, yielding data on 200 person-days for analysis in this study. Results There was no significant effect on the rest-activity cycle in the sample as a whole. Fragmentation of the rest-activity cycle was enhanced in a subgroup of persons having sleep for eight hours or less (P = 0.04 but reduced in those who preferred to sleep for more than eight hours per night (P = 0.05. The average level of motor activity was increased in persons having the morning preference for daily activity patterns (P = 0.01. Conclusion Transition into daylight saving time may have a disruptive effect on the rest-activity cycle in those healthy adults who are short-sleepers or more of the evening type.

  15. Prevalence of psychological stress, depression and anxiety among medical students in Egypt.

    Science.gov (United States)

    Fawzy, Mohamed; Hamed, Sherifa A

    2017-09-01

    Poor psychological health in medical students has been reported nationwide. This study estimated the prevalence of depression, anxiety and stress symptoms among medical students who were enrolled in a public university in Upper Egypt and determine the association of these morbidities with the students' basic socio-demographic variables. This cross-sectional study included 700 students. A self-administered, questionnaire for the socio-demographic characteristics, Depression Anxiety Stress Scale (DASS 21) and Pittsburgh Sleep Quality Index (PSQI) questionnaire were used for assessment. High frequencies of depression (65%), anxiety (73%) and stress (59.9%) were reported. Stress scores were significantly higher than depression and anxiety (P=0.001). 55.7% were poor sleepers. In univarate analysis, females, those living in the University campus/students' residence facility, in the preclinical years and with lower academic achievement had higher scores of DASS and PSQI compared to their comparative partners. Significant correlations were reported between stress with depression, anxiety and PQSI scores (P=0.0001). In multivariate analysis, stress scores were significantly associated with female sex, depression and anxiety scores. We conclude that depression, anxiety and stress symptoms are common in medical students of Assiut University relative to other schools and female gender was significantly correlated with these findings. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  16. The prevalences of and association between nonmedical prescription opioid use and poor sleep among Chinese high school students.

    Science.gov (United States)

    Tang, Daiting; Li, Pengsheng; Guo, Lan; Xu, Yan; Gao, Xue; Deng, Jianxiong; Huang, Jinghui; Huang, Guoliang; Wu, Hong; Yue, Yue; Lu, Ciyong

    2016-07-28

    The purpose of this study was to investigate the prevalences of and association between nonmedical prescription opioid use (NMPOU) and sleep quality among Chinese high school students. A cross-sectional study was conducted in Chongqing high school students in 2012, and questionnaires from 18,686 students were completed and eligible for this study. Demographic and NMPOU information was collected using a self-administered questionnaire. The Chinese Pittsburgh Sleep Quality index (CPSQI) was used to assess the occurrence of poor sleep. Among the total sample, 18.0% were classified as poor sleepers (27.4% of the subjects with past-month NMPOU), and the prevalences of lifetime, past-year and past-month NMPOU were 14.6, 4.6 and 2.8% across the entire sample, respectively. The most commonly used medicine was licorice tablets with morphine (9.1, 2.5 and 1.5% for lifetime, past-year and past-month, respectively), followed by cough syrup with codeine, Percocet, diphenoxylate and tramadol. After adjustment for potential confounders, the association between past-month NMPOU and poor sleep remained significant (AOR = 1.47, 95% CI 1.17 to 1.85). Programs aimed at decreasing NMPOU should also pay attention to sleep quality among adolescents.

  17. Insomnia in a displaced population is related to war-associated remembered stress.

    Science.gov (United States)

    Basishvili, Tamar; Eliozishvili, Marine; Maisuradze, Lia; Lortkipanidze, Nani; Nachkebia, Nargiz; Oniani, Tengiz; Gvilia, Irma; Darchia, Nato

    2012-08-01

    Although traumatic events are presumed to cause sleep disturbances, particularly insomnia, sleep in populations subjected to forced displacement has received little attention. The present study examined the prevalence of insomnia and associated factors in internally displaced persons (IDPs) from Abkhazia 15 years after displacement to Tbilisi. Detailed subjective information about sleep-wake habits, sleep-related and stress-related parameters were obtained from 87 IDPs categorized into good sleepers and insomniacs. The Insomnia Severity Index, Perceived Stress Scale and Beck Depression Inventory were administered. The incidence of insomnia was 41.4%. The majority of insomniacs strongly believed that war-related stress accounted for the onset of their insomnia. Stepwise regression (95% confidence interval) revealed four variables significantly associated with insomnia status: self-estimated influence of war related stress (odds ratio (OR) = 2.51), frequency of nightmares (OR = 1.6), Perceived Stress Scale score (OR = 1.14) and Beck Depression Inventory score (OR = 1.12). Insomnia in IDPs was strongly related to war-associated remembered stress. ‛Over thinking' about major stress exposure enhanced IDPs' vulnerability to insomnia. These findings have implications for the management of insomnia and associated impairment of daytime functioning in IDPs. Copyright © 2011 John Wiley & Sons, Ltd.

  18. The impact of economic downturns and budget cuts on homelessness claim rates across 323 local authorities in England, 2004-12.

    Science.gov (United States)

    Loopstra, Rachel; Reeves, Aaron; Barr, Ben; Taylor-Robinson, David; McKee, Martin; Stuckler, David

    2016-09-01

    It is unclear why rates of homelessness claims in England have risen since 2010. We used variations in rates across local authorities to test the impact of economic downturns and budget cuts. Using cross-area fixed effects models of data from 323 UK local authorities between 2004 and 2012, we evaluated associations of changes in statutory homelessness rates with economic activity (Gross Value Added per capita), unemployment, and local and central government expenditure. Each 10% fall in economic activity was associated with an increase of 0.45 homelessness claims per 1000 households (95% CI: 0.10-0.80). Increasing rates of homelessness were also strongly linked with government reductions in welfare spending. Disaggregating types of welfare expenditure, we found that strongest associations with reduced homelessness claims were spending on social care, housing services, discretionary housing payments and income support for older persons. Recession and austerity measures are associated with significant increases in rates of homelessness assistance. These findings likely understate the full burden of homelessness as they only capture those who seek aid. Future research is needed to investigate what is happening to vulnerable groups who may not obtain assistance, including those with mental health problems and rough sleepers. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health.

  19. Objective sleep disturbances are associated with greater waking resting-state connectivity between the retrosplenial cortex/ hippocampus and various nodes of the default mode network.

    Science.gov (United States)

    Regen, Wolfram; Kyle, Simon D; Nissen, Christoph; Feige, Bernd; Baglioni, Chiara; Hennig, Jürgen; Riemann, Dieter; Spiegelhalder, Kai

    2016-08-01

    Psychological models highlight the bidirectional role of self-referential processing, introspection, worry and rumination in the development and maintenance of insomnia; however, little is known about the underlying neural substrates. Default mode network (DMN) functional connectivity has been previously linked to these cognitive processes. We used fMRI to investigate waking DMN functional connectivity in a well-characterized sample of patients with primary insomnia (PI) and good sleeper controls. We included 20 patients with PI (8 men and 12 women, mean age 42.7 ± 13.4 yr) and 20 controls (8 men and 12 women, mean age 44.1 ± 10.6 yr) in our study. While no between-group differences in waking DMN connectivity were observed, exploratory analyses across all participants suggested that greater waking connectivity between the retrosplenial cortex/hippocampus and various nodes of the DMN was associated with lower sleep efficiency, lower amounts of rapid eye movement sleep and greater sleep-onset latency. Owing to the cross-sectional nature of the study, conclusions about causality cannot be drawn. As sleep disturbances represent a transdiagnostic symptom that is characteristic of nearly all psychiatric disorders, our results may hold particular relevance to previous findings of increased DMN connectivity levels in patients with psychiatric disorders.

  20. A linear complementarity method for the solution of vertical vehicle-track interaction

    Science.gov (United States)

    Zhang, Jian; Gao, Qiang; Wu, Feng; Zhong, Wan-Xie

    2018-02-01

    A new method is proposed for the solution of the vertical vehicle-track interaction including a separation between wheel and rail. The vehicle is modelled as a multi-body system using rigid bodies, and the track is treated as a three-layer beam model in which the rail is considered as an Euler-Bernoulli beam and both the sleepers and the ballast are represented by lumped masses. A linear complementarity formulation is directly established using a combination of the wheel-rail normal contact condition and the generalised-α method. This linear complementarity problem is solved using the Lemke algorithm, and the wheel-rail contact force can be obtained. Then the dynamic responses of the vehicle and the track are solved without iteration based on the generalised-α method. The same equations of motion for the vehicle and track are adopted at the different wheel-rail contact situations. This method can remove some restrictions, that is, time-dependent mass, damping and stiffness matrices of the coupled system, multiple equations of motion for the different contact situations and the effect of the contact stiffness. Numerical results demonstrate that the proposed method is effective for simulating the vehicle-track interaction including a separation between wheel and rail.

  1. Inflammation, Oxidative Stress, and Antioxidants Contribute to Selected Sleep Quality and Cardiometabolic Health Relationships: A Cross-Sectional Study.

    Science.gov (United States)

    Kanagasabai, Thirumagal; Ardern, Chris I

    2015-01-01

    Sleep is vital for cardiometabolic health, but a societal shift toward poor sleep is a prominent feature of many modern cultures. Concurrently, factors such as diet and lifestyle have also changed and may mediate the relationship between sleep quality and cardiometabolic health. Objectives were to explore (1) the interrelationship and (2) mediating effect of inflammation, oxidative stress, and antioxidants on sleep quality and cardiometabolic health. Cross-sectional data from the US National Health and Nutritional Examination Survey 2005-06 (≥20 y; N = 2,072) was used. Cardiometabolic health was defined as per the Joint Interim Statement; overall sleep quality was determined from six sleep habits and categorized as good, fair, poor, and very poor. Fair quality sleepers had optimal inflammation, oxidative stress, and antioxidant levels. Inflammation was above the current clinical reference range across all sleep quality categories, while oxidative stress was only within the clinical reference range for fair sleep quality. Selected sleep quality-cardiometabolic health relationships were mediated by inflammation, oxidative stress, and antioxidants and were moderated by sex. Our results provide initial evidence of a potential role for inflammation, oxidative stress, and antioxidants in the pathway between poor sleep quality-cardiometabolic decline. Further prospective research is needed to confirm our results.

  2. Identifying Effective Components of Child Maltreatment Interventions: A Meta-analysis.

    Science.gov (United States)

    van der Put, Claudia E; Assink, Mark; Gubbels, Jeanne; Boekhout van Solinge, Noëlle F

    2018-06-01

    There is a lack of knowledge about specific components that make interventions effective in preventing or reducing child maltreatment. The aim of the present meta-analysis was to increase this knowledge by summarizing findings on effects of interventions for child maltreatment and by examining potential moderators of this effect, such as intervention components and study characteristics. Identifying effective components is essential for developing or improving child maltreatment interventions. A literature search yielded 121 independent studies (N = 39,044) examining the effects of interventions for preventing or reducing child maltreatment. From these studies, 352 effect sizes were extracted. The overall effect size was significant and small in magnitude for both preventive interventions (d = 0.26, p child maltreatment. For preventive interventions, larger effect sizes were found for short-term interventions (0-6 months), interventions focusing on increasing self-confidence of parents, and interventions delivered by professionals only. Further, effect sizes of preventive interventions increased as follow-up duration increased, which may indicate a sleeper effect of preventive interventions. For curative interventions, larger effect sizes were found for interventions focusing on improving parenting skills and interventions providing social and/or emotional support. Interventions can be effective in preventing or reducing child maltreatment. Theoretical and practical implications are discussed.

  3. Screen and nonscreen sedentary behavior and sleep in adolescents.

    Science.gov (United States)

    Brunetti, Vanessa C; O'Loughlin, Erin K; O'Loughlin, Jennifer; Constantin, Evelyn; Pigeon, Étienne

    2016-12-01

    This study examined the associations between screen (computer, videogame, TV) and nonscreen (talking on the phone, doing homework, reading) sedentary time, and sleep in adolescents. Data were drawn from AdoQuest, a prospective investigation of 1843 grade 5 students aged 10-12 years at inception in the greater Montreal (Canada) area. Data for this cross-sectional analysis on screen and nonscreen sedentary time, sleep duration, and daytime sleepiness were collected in 2008-2009 from 1233 participants (67% of 1843) aged 14-16 years. Computer and videogame use >2 hours per day was associated with 17 and 11 fewer minutes of sleep per night, respectively. Computer use and talking on the phone were both associated with being a short sleeper (2 hours of computer use or talking on the phone per day had higher daytime sleepiness scores (11.9 and 13.9, respectively) than participants who reported d2 hours per day (9.7 and 10.3, respectively). Computer use and time spent talking on the phone are associated with short sleep and more daytime sleepiness in adolescents. Videogame time is also associated with less sleep. Clinicians, parents, and adolescents should be made aware that sedentary behavior and especially screen-related sedentary behavior may affect sleep duration negatively and is possibly associated with daytime sleepiness. Copyright \\© 2016 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.

  4. The relationship between lifestyle regularity and subjective sleep quality

    Science.gov (United States)

    Monk, Timothy H.; Reynolds, Charles F 3rd; Buysse, Daniel J.; DeGrazia, Jean M.; Kupfer, David J.

    2003-01-01

    In previous work we have developed a diary instrument-the Social Rhythm Metric (SRM), which allows the assessment of lifestyle regularity-and a questionnaire instrument--the Pittsburgh Sleep Quality Index (PSQI), which allows the assessment of subjective sleep quality. The aim of the present study was to explore the relationship between lifestyle regularity and subjective sleep quality. Lifestyle regularity was assessed by both standard (SRM-17) and shortened (SRM-5) metrics; subjective sleep quality was assessed by the PSQI. We hypothesized that high lifestyle regularity would be conducive to better sleep. Both instruments were given to a sample of 100 healthy subjects who were studied as part of a variety of different experiments spanning a 9-yr time frame. Ages ranged from 19 to 49 yr (mean age: 31.2 yr, s.d.: 7.8 yr); there were 48 women and 52 men. SRM scores were derived from a two-week diary. The hypothesis was confirmed. There was a significant (rho = -0.4, p subjects with higher levels of lifestyle regularity reported fewer sleep problems. This relationship was also supported by a categorical analysis, where the proportion of "poor sleepers" was doubled in the "irregular types" group as compared with the "non-irregular types" group. Thus, there appears to be an association between lifestyle regularity and good sleep, though the direction of causality remains to be tested.

  5. The interaction between sleep quality and academic performance.

    Science.gov (United States)

    Ahrberg, K; Dresler, M; Niedermaier, S; Steiger, A; Genzel, L

    2012-12-01

    Sleep quality has significant effects on cognitive performance and is influenced by multiple factors such as stress. Contrary to the ideal, medical students and residents suffer from sleep deprivation and stress at times when they should achieve the greatest amount of learning. In order to examine the relationship between sleep quality and academic performance, 144 medical students undertaking the pre-clinical board exam answered a survey regarding their subjective sleep quality (Pittsburgh sleep quality index, PSQI), grades and subjective stress for three different time points: semester, pre- and post-exam. Academic performance correlated with stress and sleep quality pre-exam (r = 0.276, p quality and high stress), however not with the stress or sleep quality during the semester and post-exam. 59% of all participants exhibited clinically relevant sleep disturbances (PSQI > 5) during exam preparation compared to 29% during the semester and 8% post-exam. This study shows that in medical students it is not the generally poor sleepers, who perform worse in the medical board exams. Instead students who will perform worse on their exams seem to be more stressed and suffer from poor sleep quality. However, poor sleep quality may negatively impact test performance as well, creating a vicious circle. Furthermore, the rate of sleep disturbances in medical students should be cause for intervention. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Tea-drinking habit among new university students: Associated factors

    Directory of Open Access Journals (Sweden)

    Hsiu Chen Tseng

    2014-02-01

    Full Text Available The habit of drinking tea is highly prevalent in Asian countries. The aim of this study was to investigate the prevalence of tea drinking and to explore the correlated factors on tea drinking among young new students in the university, using a validated self-reported questionnaire. This study was carried out with 5936 new students in a university in Taiwan. It comprised a self-administered structured questionnaire, including items related to personal and medical history, and lifestyle habits, using the Pittsburgh Sleep Quality Index (PSQI and the 12-item Chinese Health Questionnaire (CHQ-12. Anthropometric measurements and laboratory tests were also performed. In total, 2065 (36.1% students were in the tea-drinking group. Multiple logistic regression analysis showed the following factors were significant predictors of tea drinking: postgraduate students (p < 0.001, coffee drinking (p < 0.001, alcohol drinking (p < 0.001, minor mental morbidity (p = 0.009, poorer sleepers (p = 0.037, higher body mass index (p = 0.004, and sugar-sweetened beverage consumption (p < 0.001. Our data showed that the tea-drinking habit was correlated with higher body mass index, which was contrary to the findings of a previous study. In clinical practice, perhaps we could consider more tea-drinking-related factors when we suggest tea consumption.

  7. Modulation of Total Sleep Time by Transcranial Direct Current Stimulation (tDCS).

    Science.gov (United States)

    Frase, Lukas; Piosczyk, Hannah; Zittel, Sulamith; Jahn, Friederike; Selhausen, Peter; Krone, Lukas; Feige, Bernd; Mainberger, Florian; Maier, Jonathan G; Kuhn, Marion; Klöppel, Stefan; Normann, Claus; Sterr, Annette; Spiegelhalder, Kai; Riemann, Dieter; Nitsche, Michael A; Nissen, Christoph

    2016-09-01

    Arousal and sleep are fundamental physiological processes, and their modulation is of high clinical significance. This study tested the hypothesis that total sleep time (TST) in humans can be modulated by the non-invasive brain stimulation technique transcranial direct current stimulation (tDCS) targeting a 'top-down' cortico-thalamic pathway of sleep-wake regulation. Nineteen healthy participants underwent a within-subject, repeated-measures protocol across five nights in the sleep laboratory with polysomnographic monitoring (adaptation, baseline, three experimental nights). tDCS was delivered via bi-frontal target electrodes and bi-parietal return electrodes before sleep (anodal 'activation', cathodal 'deactivation', and sham stimulation). Bi-frontal anodal stimulation significantly decreased TST, compared with cathodal and sham stimulation. This effect was location specific. Bi-frontal cathodal stimulation did not significantly increase TST, potentially due to ceiling effects in good sleepers. Exploratory resting-state EEG analyses before and after the tDCS protocols were consistent with the notion of increased cortical arousal after anodal stimulation and decreased cortical arousal after cathodal stimulation. The study provides proof-of-concept that TST can be decreased by non-invasive bi-frontal anodal tDCS in healthy humans. Further elucidating the 'top-down' pathway of sleep-wake regulation is expected to increase knowledge on the fundamentals of sleep-wake regulation and to contribute to the development of novel treatments for clinical conditions of disturbed arousal and sleep.

  8. Using Continuous In-situ Measurement of Fluorescence to Reveal Hot Spots and Hot Moments of Dissolved Organic Matter Dynamics in a Forested Watershed

    Science.gov (United States)

    Ryan, K. A.; Hosen, J. D.; Raymond, P. A.; Stubbins, A.; Shanley, J. B.

    2017-12-01

    River systems serve as net carbon exporters from land to the ocean, fueling downstream aquatic ecosystem food webs. Fluorescence signatures of aquatic organic matter can be used as a proxy for dissolved organic carbon (DOC) concentration and can characterize DOC composition, reactivity, and source to improve our understanding of ecological processes. In-situ measurement of fluorescence using fifteen-minute interval data logging allows greater temporal resolution than laboratory studies. However, in-situ data must be corrected for interferences from temperature, absorbance and turbidity changes occurring in the field. We installed multiparameter water quality sondes (Eureka Mantas) and in-situ fluorometers (Turner Designs Cyclops) at sites nested within streams and riparian zones in the Sleepers River Research Watershed in Vermont in 2017. We coupled these measurements with simultaneous intensive field sampling campaigns and laboratory analysis of DOC and fluorescence Excitation-Emission Matrices. The data loggers from the nested sites recorded fluorescence peaks responding to discharge events and tracked changes in fluorescence occurring from upstream to downstream sites. Laboratory results confirm a nonlinear, hysteretic relationship between discharge and DOC where peak DOC lags peak discharge. This hysteresis is predicted to be controlled by multiple flow paths and DOC sources (i.e. groundwater, overland flow). We conclude that continuous in-situ records of river water fluorescence can be used to inform ecological processes and test new hypotheses concerning dissolved organic matter dynamics in watersheds.

  9. Sleep duration and age-related changes in brain structure and cognitive performance.

    Science.gov (United States)

    Lo, June C; Loh, Kep Kee; Zheng, Hui; Sim, Sam K Y; Chee, Michael W L

    2014-07-01

    To investigate the contribution of sleep duration and quality to age-related changes in brain structure and cognitive performance in relatively healthy older adults. Community-based longitudinal brain and cognitive aging study using a convenience sample. Participants were studied in a research laboratory. Relatively healthy adults aged 55 y and older at study commencement. N/A. Participants underwent magnetic resonance imaging and neuropsychological assessment every 2 y. Subjective assessments of sleep duration and quality and blood samples were obtained. Each hour of reduced sleep duration at baseline augmented the annual expansion rate of the ventricles by 0.59% (P = 0.007) and the annual decline rate in global cognitive performance by 0.67% (P = 0.050) in the subsequent 2 y after controlling for the effects of age, sex, education, and body mass index. In contrast, global sleep quality at baseline did not modulate either brain or cognitive aging. High-sensitivity C-reactive protein, a marker of systemic inflammation, showed no correlation with baseline sleep duration, brain structure, or cognitive performance. In healthy older adults, short sleep duration is associated with greater age-related brain atrophy and cognitive decline. These associations are not associated with elevated inflammatory responses among short sleepers. Lo JC, Loh KK, Zheng H, Sim SK, Chee MW. Sleep duration and age-related changes in brain structure and cognitive performance.

  10. [The effect of acupuncture in the treatment of insomnia. Clinical study of subjective and objective evaluation].

    Science.gov (United States)

    Montakab, H; Langel, G

    1994-01-01

    The sleep-wake cycle is the most important circadian rhythm in man and thus constitutes an excellent indicator of internal equilibrium and of health. Sleep disorders, and particularly insomnia, affect a great percentage of the population. In daily practice, an inappropriate treatment may transform a bad sleeper into an insomniac dependent on pharmaceuticals for life. It is therefore necessary to give priority to non-chemical treatments in the management of insomnia. Acupuncture, which offers a personalized treatment, is particularly indicated for reharmonizing a disturbed sleep-wake cycle. Furthermore, there is an interesting similarity between the 5000-year-old theoretical basis of Chinese medicine and the recent scientific discoveries about man's internal rhythms. Clinical and statistical studies of the effects of acupuncture on insomnia are rare and evaluate only the subjective appreciation of sleep. Objective analysis of sleep by polysomnography permits evaluation of sleep architecture and visualizes the site and depth of action of the therapeutic method. Such studies have only been conducted in relation to pharmaceutical treatments. No such study has been carried out for acupuncture. A scientific and objective evaluation of the effects of acupuncture on insomnia by polysomnography could be not only of academic but mainly of great practical interest. If the efficiency of acupuncture is thus verified, this method could be integrated and proposed along with other classical therapeutic technics.

  11. EVALUATING COMMERCIALLY AVAILABLE DERMAL ...

    Science.gov (United States)

    As the Human Exposure Program focuses on the exposure of children to pesticides, there are concerns about the effect, or perceived effect, of components of the sampling procedure on the health and well-being of the infant and the ability to collect pesticide residues. One concern involves the materials in wipes used to collect pesticide residues or other contact materials on the skin. In recent studies (e.g., National Human Exposure Assessment Survey; NHEXAS), isopropyl alcohol has been used as a solvent in conjunction with a cloth wipe to obtain samples from the hands of adults and children. Although isopropyl alcohol is generally considered innocuous, the use of commercially available products could eliminate concerns about exposure to alcohol. A few studies have evaluated the potential of commercially available baby wipes to collect personal exposure samples for metals research, but not for the area of pesticide research (Millson et al., 1994; Campbell et al., 1993; Lichtenwalner et al., 1993). Therefore, there is a need to evaluate the potential for using commercially available baby wipes for collecting pesticide samples from skin and other surfaces. Another concern involves establishing a convenient and safe method for assessing overall dermal exposure for children, especially for those in crawling stage. One route that the U .S. Environmental Protection Agency (EPA) would like to investigate is the use of cotton body suits (infant sleepers) as an indicator

  12. A Feasibility Study on the Application of Basic Oxygen Furnace (BOF Steel Slag for Railway Ballast Material

    Directory of Open Access Journals (Sweden)

    Taehoon Koh

    2018-01-01

    Full Text Available Railway ballast, for which natural crushed stone aggregates have been generally used, is an essential track component for the distribution of train loads along the rails and sleepers to the roadbed. However, the use of natural crushed stone aggregate causes environmental destruction as well as dust production in train service. This paper evaluates the feasibility of using the basic oxygen furnace (BOF steel slag as railway ballast material. A series of physical and chemical quality tests are performed to investigate the characteristics of the materials associated with the effect of aging period due to the remaining free CaO and MgO in the BOF steel slag. Three different aging periods (i.e., 0, 3, and 6 months are used to compare with various standards and the properties of the crushed stone aggregates. It is demonstrated that the physical and chemical properties of the BOF steel slag with different aging periods satisfy all requirements of standards sufficiently. Especially, the BOF steel slag without aging (i.e., 0 month provides the similar physical and chemical properties, when compared to the BOF steel slag with aging (i.e., 3 and 6 months. Thus, it is possible to apply the BOF steel slag regardless of aging periods to the railway ballast materials instead of natural crushed stone aggregates.

  13. Declarative virtual water maze learning and emotional fear conditioning in primary insomnia.

    Science.gov (United States)

    Kuhn, Marion; Hertenstein, Elisabeth; Feige, Bernd; Landmann, Nina; Spiegelhalder, Kai; Baglioni, Chiara; Hemmerling, Johanna; Durand, Diana; Frase, Lukas; Klöppel, Stefan; Riemann, Dieter; Nissen, Christoph

    2018-05-02

    Healthy sleep restores the brain's ability to adapt to novel input through memory formation based on activity-dependent refinements of the strength of neural transmission across synapses (synaptic plasticity). In line with this framework, patients with primary insomnia often report subjective memory impairment. However, investigations of memory performance did not produce conclusive results. The aim of this study was to further investigate memory performance in patients with primary insomnia in comparison to healthy controls, using two well-characterized learning tasks, a declarative virtual water maze task and emotional fear conditioning. Twenty patients with primary insomnia according to DSM-IV criteria (17 females, three males, 43.5 ± 13.0 years) and 20 good sleeper controls (17 females, three males, 41.7 ± 12.8 years) were investigated in a parallel-group study. All participants completed a hippocampus-dependent virtual Morris water maze task and amygdala-dependent classical fear conditioning. Patients with insomnia showed significantly delayed memory acquisition in the virtual water maze task, but no significant difference in fear acquisition compared with controls. These findings are consistent with the notion that memory processes that emerge from synaptic refinements in a hippocampal-neocortical network are particularly sensitive to chronic disruptions of sleep, while those in a basic emotional amygdala-dependent network may be more resilient. © 2018 European Sleep Research Society.

  14. Biomechanics-based active control of bedding support properties and its influence on sleep.

    Science.gov (United States)

    Van Deun, D; Verhaert, V; Willemen, T; Wuyts, J; Verbraecken, J; Exadaktylos, V; Haex, B; Vander Sloten, J

    2012-01-01

    Proper body support plays an import role in the recuperation of our body during sleep. Therefore, this study uses an automatically adapting bedding system that optimises spinal alignment throughout the night by altering the stiffness of eight comfort zones. The aim is to investigate the influence of such a dynamic sleep environment on objective and subjective sleep parameters. The bedding system contains 165 sensors that measure mattress indentation. It also includes eight actuators that control the comfort zones. Based on the measured mattress indentation, body movements and posture changes are detected. Control of spinal alignment is established by fitting personalized human models in the measured indentation. A total of 11 normal sleepers participated in this study. Sleep experiments were performed in a sleep laboratory where subjects slept three nights: a first night for adaptation, a reference night and an active support night (in counterbalanced order). Polysomnographic measurements were recorded during the nights, combined with questionnaires aiming at assessing subjective information. Subjective information on sleep quality, daytime quality and perceived number of awakenings shows significant improvements during the active support (ACS) night. Objective results showed a trend towards increased slow wave sleep. On the other hand, it was noticed that % N1-sleep was significantly increased during ACS night, while % N2-sleep was significantly decreased. No prolonged N1 periods were found during or immediately after steering.

  15. Stress and sleep reactivity: a prospective investigation of the stress-diathesis model of insomnia.

    Science.gov (United States)

    Drake, Christopher L; Pillai, Vivek; Roth, Thomas

    2014-08-01

    To prospectively assess sleep reactivity as a diathesis of insomnia, and to delineate the interaction between this diathesis and naturalistic stress in the development of insomnia among normal sleepers. Longitudinal. Community-based. 2,316 adults from the Evolution of Pathways to Insomnia Cohort (EPIC) with no history of insomnia or depression (46.8 ± 13.2 y; 60% female). None. Participants reported the number of stressful events they encountered at baseline (Time 1), as well as the level of cognitive intrusion they experienced in response to each stressor. Stressful events (OR = 1.13; P stress-induced cognitive intrusion (OR = 1.61; P stressful events on risk for insomnia (P sleep reactivity significantly increased risk for insomnia (OR = 1.78; P sleep reactivity moderated the effects of stress-induced intrusion (P sleep reactivity. Trait sleep reactivity also constituted a significant risk for depression (OR = 1.67; P sleep reactivity is a significant risk factor for incident insomnia, and that it triggers insomnia by exacerbating the effects of stress-induced intrusion. Sleep reactivity is also a precipitant of depression, as mediated by insomnia. These findings support the stress-diathesis model of insomnia, while highlighting sleep reactivity as an important diathesis. Drake CL, Pillai V, Roth T. Stress and sleep reactivity: a prospective investigation of the stress-diathesis model of insomnia.

  16. Cu,Cr and As determination in preserved woods (Eucalyptus ssp.) by X-ray fluorescence spectrometries; Determinacao de cobre, cromo e arsenio em madeira preservada (Eucalyptus sp.) pelas espectrometrias de fluorescencia de raios X

    Energy Technology Data Exchange (ETDEWEB)

    Pereira Junior, Sergio Matias

    2014-07-01

    Brazil produces around 2.2 millions of cubic meters of treated wood to meet the annual demand of railway, electric, rural and construction sectors. The most used wood species are eucalyptus (Eucalyptus ssp.) and pine (Pinus ssp.).The treated woods used for poles, sleepers, fence posts and plywoods should be according to Brazilian norms requirements. The most usual wood preservative products used in Brazil are CCA (chromated copper arsenate) and CCB (copper chromium and boron salt). The analytical methods, such as flame atomic absorption spectrometry (FAAS), plasma inductively coupled optical emission spectrometry (ICPOES) and X-ray fluorescence spectrometry (XRFS) have been used for the analytical control of those treatment processes. In this work, the eucalyptus trees (Eucalyptus ssp) samples was obtained from Minas Gerais State, Brazil, cut plantation areas. Under pressure, eucalyptus wood samples were submitted to different concentration of CCA solution reaching 3.9, 6.7, 9.1, 12.4 and 14.0 kg of CCA by m-³ sapwood retentions. Samples in cylinders and sawdust forms were obtained from treated wood samples. Copper, chromium and arsenic determination was performed using the energy dispersive X-ray fluorescence spectrometry (EDXRFS), portable X-ray fluorescence spectrometry (PXRFS), flame atomic absorption spectrometry (FAAS) and instrumental neutron activation analysis. In this work, the method of analysis, sensitivity, precision and accuracy performances of the related techniques were outlined. (author)

  17. Cu,Cr and As determination in preserved woods (Eucalyptus ssp.) by X-ray fluorescence spectrometries

    International Nuclear Information System (INIS)

    Pereira Junior, Sergio Matias

    2014-01-01

    Brazil produces around 2.2 millions of cubic meters of treated wood to meet the annual demand of railway, electric, rural and construction sectors. The most used wood species are eucalyptus (Eucalyptus ssp.) and pine (Pinus ssp.).The treated woods used for poles, sleepers, fence posts and plywoods should be according to Brazilian norms requirements. The most usual wood preservative products used in Brazil are CCA (chromated copper arsenate) and CCB (copper chromium and boron salt). The analytical methods, such as flame atomic absorption spectrometry (FAAS), plasma inductively coupled optical emission spectrometry (ICPOES) and X-ray fluorescence spectrometry (XRFS) have been used for the analytical control of those treatment processes. In this work, the eucalyptus trees (Eucalyptus ssp) samples was obtained from Minas Gerais State, Brazil, cut plantation areas. Under pressure, eucalyptus wood samples were submitted to different concentration of CCA solution reaching 3.9, 6.7, 9.1, 12.4 and 14.0 kg of CCA by m-³ sapwood retentions. Samples in cylinders and sawdust forms were obtained from treated wood samples. Copper, chromium and arsenic determination was performed using the energy dispersive X-ray fluorescence spectrometry (EDXRFS), portable X-ray fluorescence spectrometry (PXRFS), flame atomic absorption spectrometry (FAAS) and instrumental neutron activation analysis. In this work, the method of analysis, sensitivity, precision and accuracy performances of the related techniques were outlined. (author)

  18. O gigante dormente: O lugar nos trilhos da ferrovia Norte-Sul / The railway sleeper giant: The place in the tracks of the North-South railroad

    Directory of Open Access Journals (Sweden)

    Arlete Mendes Mendes da Silva

    2014-04-01

    Full Text Available The Great Engineering Projects are events that change the space, altering their natural and socio-cultural elements. The socio-spatial effects of these developments can be positive and / or negative. The construction of the North – South railway is considered a major project. This suggests a path with railways of approximately 2100 km across the Midwest and north of the country, connecting the north with the Carajás Railroad and south with the Central Atlantic Railroad. With that reduces freight costs for long distances, and can raise the economic development of the Brazilian Cerrado. Despite the developmental objectives of the FNS, this paper seeks to reflect on the impact that the railroad can bring to the rural and urban in the city of Anápolis - GO, taking place as a category of this analysis. There is no way to integrate, include, accommodate a large number of people who ‘has no place’ in society exclusionary. Moreover, the forms of inclusion and reinstatement are increasingly encountered and degrading little to a condition of social welfare. Aiming to spatialize and illustrate this reflection, the geographical treatment that is intended to give the perspective of space - place mentions the construction of a major infrastructure project in the transport logistics Mid- Region the Center of Goiás, at the southern entrance of the city of Anápolis, in State of Goiás, the North South Railway - FNS and its socio-spatial implications.

  19. A hydrometric and geochemical approach to test the transmissivity feedback hypothesis during snowmelt

    Science.gov (United States)

    Kendall, K.A.; Shanley, J.B.; McDonnell, Jeffery J.

    1999-01-01

    To test the transmissivity feedback hypothesis of runoff generation, surface and subsurface waters were monitored and sampled during the 1996 snowmelt at various topographic positions in a 41 ha forested headwater catchment at Sleepers River, Vermont. Two conditions that promote transmissivity feedback existed in the catchment during the melt period. First, saturated hydraulic conductivity increased toward land surface, from a geometric mean of 3.6 mm h-1 in glacial till to 25.6 mm h-1 in deep soil to 54.0 mm h-1 in shallow soil. Second, groundwater levels rose to within 0.3 m of land surface at all riparian sites and most hillslope sites at peak melt. The importance of transmissivity feedback to streamflow generation was tested at the catchment scale by examination of physical and chemical patterns of groundwater in near-stream (discharge) and hillslope (recharge/lateral flow) zones, and within a geomorphic hollow (convergent flow). The presence of transmissivity feedback was supported by the abrupt increase in streamflow as the water table rose into the surficial, transmissive zone; a flattening of the groundwater level vs. streamflow curve occurred at most sites. This relation had a clockwise hysteresis (higher groundwater level for given discharge on rising limb than at same discharge on falling limb) at riparian sites, suggesting that the riparian zone was the dominant source area during the rising limb of the melt hydrograph. Hysteresis was counterclockwise at hillslope sites, suggesting that hillslope drainage controlled the snowmelt recession. End member mixing analysis using Ca, Mg, Na, dissolved organic carbon (DOC), and Si showed that stream chemistry could be explained as a two-component mixture of groundwater high in base cations and an O-horizon/overland flow water high in DOC. The dominance of shallow flow paths during events was indicated by the high positive correlation of DOC with streamflow (r2 = 0.82). Despite the occurrence of transmissivity

  20. Shift work, night work and sleep disorders among pastry cookers and shopkeepers in France: a cross-sectional survey.

    Science.gov (United States)

    Pepin, Emilie; Gillet, Pascal; Sauvet, Fabien; Gomez-Merino, Danielle; Thaon, Isabelle; Chennaoui, Mounir; Leger, Damien

    2018-05-09

    Most research on night and shift work focuses on employee health in large companies, primarily in the healthcare and transportation sectors. However, many night workers work on their own or in small businesses related to services or food. This survey focuses on sleep habits and disorders concerning night work in pastry production and sales. An epidemiological telephone cross-sectional survey of night shift workers and their sleep habits was proposed to all employers and employees in the French pastry industry via their insurance health prevention company. Sleep logs allow us to estimate the total sleep time (TST) on workdays and enquire on napping episodes and length. In order to estimate the ideal TST, we added a question on the ideal amount of sleep the subjects need to be in good shape in the morning. We also define sleep debt as the difference between the ideal TST and TST on workdays, and considered a sleep debt when the difference was above 60 min and severe sleep debt above 90 min. Finally we retained subjects as long sleepers for those with a TSTof more than 7 hours and short sleepers when TST was under 5 hours. Insomnia, sleepiness and sleep apnoea have been defined based on the International Classification of Sleep Disorders-Third Edition and the classification of mental disorders (Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition). Bivariate and multivariate logistic regression models were applied to investigate the association with short TST, long TST, sleep debt and napping. We analysed 2622 complete questionnaires from 1313 men and 1309 women aged 22-50 years old. 1397 workers began work before 07:00, whereas 1225 began later. The 24-hour TST was 6.7±1.4 hours, whereas the ideal TST was 7.0±1.2 hours. Severe sleep debt (>90 min) was reported by 6% women versus 5% men, whereas moderate sleep debt (>60 min) was reported by 11.5% women versus 9.3% men. Napping is one way to improve 24-hour TST for 58% of pastry

  1. Magnetic Resonance Spectroscopy in Patients with Insomnia: A Repeated Measurement Study.

    Directory of Open Access Journals (Sweden)

    Kai Spiegelhalder

    Full Text Available Chronic insomnia is one of the most prevalent central nervous system disorders. It is characterized by increased arousal levels, however, the neurobiological causes and correlates of hyperarousal in insomnia remain to be further determined. In the current study, magnetic resonance spectroscopy was used in the morning and evening in a well-characterized sample of 20 primary insomnia patients (12 females; 8 males; 42.7 ± 13.4 years and 20 healthy good sleepers (12 females; 8 males; 44.1 ± 10.6 years. The most important inhibitory and excitatory neurotransmitters of the central nervous system, γ-aminobutyric acid (GABA and glutamate/glutamine (Glx, were assessed in the anterior cingulate cortex (ACC and dorsolateral prefrontal cortex (DLPFC. The primary hypothesis, a diurnal effect on GABA levels in patients with insomnia, could not be confirmed. Moreover, the current results did not support previous findings of altered GABA levels in individuals with insomnia. Exploratory analyses, however, suggested that GABA levels in the ACC may be positively associated with habitual sleep duration, and, thus, reduced GABA levels may be a trait marker of objective sleep disturbances. Moreover, there was a significant GROUP x MEASUREMENT TIME interaction effect on Glx in the DLPFC with increasing Glx levels across the day in the patients but not in the control group. Therefore, Glx levels may reflect hyperarousal at bedtime in those with insomnia. Future confirmatory studies should include larger sample sizes to investigate brain metabolites in different subgroups of insomnia.

  2. The exploratory power of sleep effort, dysfunctional beliefs and arousal for insomnia severity and polysomnography-determined sleep.

    Science.gov (United States)

    Hertenstein, Elisabeth; Nissen, Christoph; Riemann, Dieter; Feige, Bernd; Baglioni, Chiara; Spiegelhalder, Kai

    2015-08-01

    Differences between subjective sleep perception and sleep determined by polysomnography (PSG) are prevalent, particularly in patients with primary insomnia, indicating that the two measures are partially independent. To identify individualized treatment strategies, it is important to understand the potentially different mechanisms influencing subjective and PSG-determined sleep. The aim of this study was to investigate to what extent three major components of insomnia models, i.e., sleep effort, dysfunctional beliefs and attitudes about sleep, and presleep arousal, are associated with subjective insomnia severity and PSG-determined sleep. A sample of 47 patients with primary insomnia according to DSM-IV criteria and 52 good sleeper controls underwent 2 nights of PSG and completed the Glasgow Sleep Effort Scale, the Dysfunctional Beliefs and Attitudes about Sleep Scale, the Pre-Sleep Arousal Scale and the Insomnia Severity Index. Regression analyses were conducted to investigate the impact of the three predictors on subjective insomnia severity and PSG- determined total sleep time. All analyses were adjusted for age, gender, depressive symptoms and group status. The results showed that subjective insomnia severity was associated positively with sleep effort. PSG-determined total sleep time was associated negatively with somatic presleep arousal and dysfunctional beliefs and attitudes about sleep. This pattern of results provides testable hypotheses for prospective studies on the impact of distinct cognitive and somatic variables on subjective insomnia severity and PSG-determined total sleep time. © 2015 European Sleep Research Society.

  3. The periodicity of sleep duration – an infradian rhythm in spontaneous living

    Directory of Open Access Journals (Sweden)

    Wong SN

    2013-01-01

    Full Text Available Shi Ngar Wong, Mark Halaki, Chin Moi ChowDiscipline of Exercise and Sport Science, University of Sydney, Sydney, NSW, AustraliaAbstract: The sleep–wake cycle is a process not only dictated by homeostatic and circadian factors but also by social and environmental influences. Thus, the total sleep time partly reflects sleep need, which is integral to the dynamics of sleep loss recovery. This study explored the nature of the observed oscillations in total sleep time in healthy adults under spontaneous living conditions. Actigraph-measured sleep data for 13 healthy young male adults were collected over 14 consecutive days and analyzed for habitual sleep duration. The total sleep time periodicity was modeled using the cosinor method for each individual across the 14 days. The findings confirm the existence of periodicity in habitual sleep duration as there were clear periodic patterns in the majority of the participants. Although exclusive to each individual, the observed oscillations may be a resultant response of homeostatic sleep need, circadian timing, and/or social and environmental influences. These findings instigate further indepth studies into the periodicity of sleep duration in healthy individuals to provide a better understanding of sleep need in short versus long sleepers, in predicting work performance, and reducing sleepiness-related accidents following shift work, and how this periodicity may impact sleep treatment outcome in clinical populations.Keywords: sleep regulation, homeostasis, habitual sleep, spontaneous living, healthy males

  4. Nizhny Novgorod Belyana barge in the XIX century

    Directory of Open Access Journals (Sweden)

    Philippov Yury V.

    2015-01-01

    Full Text Available The article discusses a unique Belyana barge, which was built in the Nizhny Novgorod region for several centuries. Belyana as a type of vessels was designed for transportation of logs, sleepers, beams, planks and other forest products from the Upper to the Lower Volga. Originally, the center of Belyana construction was the village of Baki, which was situated on the Vetluga River, a tributary of the Volga River. The Belyana construction technique spread from the Vetluga river banks further to Nizhny Novgorod, and then to Perm region. Almost all aspects of Belyana construction starting from the logging finishing with its floating to the lower Volga, and also cost of transported products in the prices of the XIX century are disclosed. Due to Belyana is truly a popular invention, it was built by traditional methods, relying solely on the centuries-old experience. Any drawings for the construction never existed, that’s why the author relied on preserved photographs and drawings in the historical reconstruction of this unique vessel. At the beginning of the article a brief overview of the geographical location of Nizhny Novgorod, as well as the names of wooden ships which were sailing on Volga and its tributaries in the same times with Belyana are given. At the end of the article practical recommendations on possible reconstruction of Belyana and using it as an interactive museum of ethnography are given.

  5. Defences against ammonia toxicity in tropical air-breathing fishes exposed to high concentrations of environmental ammonia: a review.

    Science.gov (United States)

    Ip, Y K; Chew, S F; Wilson, J M; Randall, D J

    2004-10-01

    In the tropics, air-breathing fishes can be exposed to environmental ammonia when stranded in puddles of water during the dry season, during a stay inside a burrow, or after agricultural fertilization. At low concentrations of environmental ammonia, NH(3) excretion is impeded, as in aerial exposure, leading to the accumulation of endogenous ammonia. At high concentrations of environmental ammonia, which results in a reversed NH(3) partial pressure gradient (DeltaP(NH3)), there is retention of endogenous ammonia and uptake of exogenous ammonia. In this review, several tropical air-breathing fishes (giant mudskipper, African catfish, oriental weatherloach, swamp eel, four-eyed sleeper, abehaze and slender African lungfish), which can tolerate high environmental ammonia exposure, are used as examples to demonstrate how eight different adaptations can be involved in defence against ammonia toxicity. Four of these adaptations deal with ammonia toxicity at branchial and/or epithelial surfaces: (1) active excretion of NH(4)(+); (2) lowering of environmental pH; (3) low NH(3) permeability of epithelial surfaces; and (4) volatilization of NH(3), while another four adaptations ameliorate ammonia toxicity at the cellular and subcellular levels: (5) high tolerance of ammonia at the cellular and subcellular levels; (6) reduction in ammonia production; (7) glutamine synthesis; and (8) urea synthesis. The responses of tropical air-breathing fishes to high environmental ammonia are determined apparently by behavioural adaptations and the nature of their natural environments.

  6. Increased use-dependent plasticity in chronic insomnia.

    Science.gov (United States)

    Salas, Rachel E; Galea, Joseph M; Gamaldo, Alyssa A; Gamaldo, Charlene E; Allen, Richard P; Smith, Michael T; Cantarero, Gabriela; Lam, Barbara D; Celnik, Pablo A

    2014-03-01

    During normal sleep several neuroplasticity changes occur, some of which are considered to be fundamental to strengthen memories. Given the evidence linking sleep to neuroplasticity, it is conceivable that individuals with chronic sleep disruption, such as patients with chronic insomnia (CI), would experience abnormalities in neuroplastic processes during daytime. Protocols testing use-dependent plasticity (UDP), one of the mechanisms underlying formation of motor memories traces, provide a sensitive measure to assess neuroplasticity in the context of motor training. A well-established transcranial magnetic stimulation (TMS) paradigm was used to evaluate the ability of patients with CI and age-matched good sleeper controls to undergo UDP. We also investigated the effect of insomnia on intracortical motor excitability measures reflecting GABAergic and glutamatergic mechanisms. Human Brain Physiology Laboratory, Johns Hopkins Medical Institutions. We found that patients with CI experienced increased UDP changes relative to controls. This effect was not due to differences in motor training. In addition, patients with CI showed enhanced intracortical facilitation relative to controls, in the absence of changes in intracortical inhibitory measures. This study provides the first evidence that patients with chronic insomnia have an increased plasticity response to physical exercise, possibly due to larger activation of glutamatergic mechanisms. This suggests a heightened state of neuroplasticity, which may reflect a form of maladaptive plasticity, similar to what has been described in dystonia patients and chronic phantom pain after amputation. These results could lead to development of novel treatments for chronic insomnia.

  7. Information processing during NREM sleep and sleep quality in insomnia.

    Science.gov (United States)

    Ceklic, Tijana; Bastien, Célyne H

    2015-12-01

    Insomnia sufferers (INS) are cortically hyperaroused during sleep, which seems to translate into altered information processing during nighttime. While information processing, as measured by event-related potentials (ERPs), during wake appears to be associated with sleep quality of the preceding night, the existence of such an association during nighttime has never been investigated. This study aims to investigate nighttime information processing among good sleepers (GS) and INS while considering concomitant sleep quality. Following a multistep clinical evaluation, INS and GS participants underwent 4 consecutive nights of PSG recordings in the sleep laboratory. Thirty nine GS (mean age 34.56±9.02) and twenty nine INS (mean age 43.03±9.12) were included in the study. ERPs (N1, P2, N350) were recorded all night on Night 4 (oddball paradigm) during NREM sleep. Regardless of sleep quality, INS presented a larger N350 amplitude during SWS (p=0.042) while GS showed a larger N350 amplitude during late-night stage 2 sleep (p=0.004). Regardless of diagnosis, those who slept objectively well showed a smaller N350 amplitude (p=0.020) while those who slept subjectively well showed a smaller P2 (pInformation processing seems to be associated with concomitant subjective and objective sleep quality for both GS and INS. However, INS show an alteration in information processing during sleep, especially for inhibition processes, regardless of their sleep quality. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Inducing task-relevant responses to speech in the sleeping brain.

    Science.gov (United States)

    Kouider, Sid; Andrillon, Thomas; Barbosa, Leonardo S; Goupil, Louise; Bekinschtein, Tristan A

    2014-09-22

    Falling asleep leads to a loss of sensory awareness and to the inability to interact with the environment [1]. While this was traditionally thought as a consequence of the brain shutting down to external inputs, it is now acknowledged that incoming stimuli can still be processed, at least to some extent, during sleep [2]. For instance, sleeping participants can create novel sensory associations between tones and odors [3] or reactivate existing semantic associations, as evidenced by event-related potentials [4-7]. Yet, the extent to which the brain continues to process external stimuli remains largely unknown. In particular, it remains unclear whether sensory information can be processed in a flexible and task-dependent manner by the sleeping brain, all the way up to the preparation of relevant actions. Here, using semantic categorization and lexical decision tasks, we studied task-relevant responses triggered by spoken stimuli in the sleeping brain. Awake participants classified words as either animals or objects (experiment 1) or as either words or pseudowords (experiment 2) by pressing a button with their right or left hand, while transitioning toward sleep. The lateralized readiness potential (LRP), an electrophysiological index of response preparation, revealed that task-specific preparatory responses are preserved during sleep. These findings demonstrate that despite the absence of awareness and behavioral responsiveness, sleepers can still extract task-relevant information from external stimuli and covertly prepare for appropriate motor responses. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Sleep-related memory consolidation in primary insomnia.

    Science.gov (United States)

    Nissen, Christoph; Kloepfer, Corinna; Feige, Bernd; Piosczyk, Hannah; Spiegelhalder, Kai; Voderholzer, Ulrich; Riemann, Dieter

    2011-03-01

    It has been suggested that healthy sleep facilitates the consolidation of newly acquired memories and underlying brain plasticity. The authors tested the hypothesis that patients with primary insomnia (PI) would show deficits in sleep-related memory consolidation compared to good sleeper controls (GSC). The study used a four-group parallel design (n=86) to investigate the effects of 12 h of night-time, including polysomnographically monitored sleep ('sleep condition' in PI and GSC), versus 12 h of daytime wakefulness ('wake condition' in PI and GSC) on procedural (mirror tracing task) and declarative memory consolidation (visual and verbal learning task). Demographic characteristics and memory encoding did not differ between the groups at baseline. Polysomnography revealed a significantly disturbed sleep profile in PI compared to GSC in the sleep condition. Night-time periods including sleep in GSC were associated with (i) a significantly enhanced procedural and declarative verbal memory consolidation compared to equal periods of daytime wakefulness in GSC and (ii) a significantly enhanced procedural memory consolidation compared to equal periods of daytime wakefulness and night-time sleep in PI. Across retention intervals of daytime wakefulness, no differences between the experimental groups were observed. This pattern of results suggests that healthy sleep fosters the consolidation of new memories, and that this process is impaired for procedural memories in patients with PI. Future work is needed to investigate the impact of treatment on improving sleep and memory. © 2010 European Sleep Research Society.

  10. The effect of intraosseous local anesthesia of 4% articaine with 1:100,000 epinephrine on pulpal blood flow and pulpal anesthesia of mandibular molars and canines.

    Science.gov (United States)

    Vongsavan, Kadkao; Samdrup, Tshering; Kijsamanmith, Kanittha; Rirattanapong, Praphasri; Vongsavan, Noppakun

    2018-05-10

    The aim of this study was to determine the effect of intraosseous (IO) anesthesia with 4% articaine and 1:100,000 epinephrine on pulpal blood flow (PBF) and pulpal anesthesia of mandibular first molars and canines in human subjects. Ten healthy volunteers with intact mandibular first molar and canine were given an osteocentral technique of IO injection using the Quick Sleeper 5 system and 4% articaine with 1:100,000 epinephrine at distal site of mandibular first molar. The PBF was monitored by a laser Doppler flowmeter (LDF). Pulpal anesthesia was assessed with an electric pulp tester (EPT). IO injection caused a decrease in PBF in molars from 6.31 ± 3.85 perfusion units (P.U.) before injection to 2.51 ± 2.53 P.U. 1 min after injection (P anesthesia in the molars, the mean onset was 2.40 ± 0.84 min and the mean duration was 38 ± 16.19 min. In the canines, there was a decrease in the sensitivity to EPT but complete pulpal anesthesia was not achieved. IO injection distal to mandibular first molar caused a decrease in PBF and successful pulpal anesthesia in first molar, but not in canine. Both PBF and EPT readings returned to normal, suggesting that pulpal ischemia may not occur. IO anesthesia is safe to use as a primary technique in teeth with normal pulp.

  11. Crew Factors in Flight Operations. 8; A Survey of Fatigue Factors in Corporate/Executive A Viation Operations

    Science.gov (United States)

    Rosekind, Mark R.; Co, Elizabeth L.; Gregory, Kevin B.; Miller, Donna L.

    2000-01-01

    Corporate flight crews face unique challenges including unscheduled flights, quickly changing schedules, extended duty days, long waits, time zone changes, and peripheral tasks. Most corporate operations are regulated by Part 91 FARs which set no flight or duty time limits. The objective of this study was to identify operationally significant factors that may influence fatigue, alertness, and performance in corporate operations. In collaboration with the National Business Aircraft Association and the Flight Safety Foundation, NASA developed and distributed a retrospective survey comprising 107 questions addressing demographics, home sleep habits, flight experience, duty schedules, fatigue during operations, and work environment. Corporate crewmembers returned 1,488 surveys. Respondents averaged 45.2 years of age, had 14.9 years of corporate flying experience, and 9,750 total flight hours. The majority (89%) rated themselves as 'good' or 'very good' sleepers at home. Most (82%) indicated they are subject to call for duty and described an average duty day of 9.9 h. About two-thirds reported having a daily duty time limit and over half (57%) reported a daily flight time limit. Nearly three-quarters (71%) acknowledged having 'nodded off' during a flight. Only 21% reported that their flight departments offer training on fatigue issues. Almost three-quarters (74%) described fatigue as a 'moderate' or 'serious' concern, and a majority (61%) characterized it as a common occurrence. Most (85%) identified fatigue as a 'moderate' or 'serious' safety issue.

  12. Quality of sleep for hospitalized patients in Rasoul-Akram hospital.

    Science.gov (United States)

    Ghanbari Jolfaei, Atefeh; Makvandi, Alena; Pazouki, Abdolreza

    2014-01-01

    Sleep disturbances have negative effects on medical conditions, mental health and cognitive performance. It was shown that about 60% of inpatients suffer from sleep problems. The aim of this study was to assess the correlation between sleep quality and other factors in the inpatients of Rasoul-e-Akram hospital. In this cross-sectional study, all the hospitalized patients in twelve wards of Rasoul-e-Akram hospital during September 2012, were examined. Sleeping habits of 209 inpatients of different wards were assessed through the Persian version of Pittsburgh Sleep Questionnaire (PSQI). A self-designed 18- question questionnaire was conducted for all patients in order to assess their attitude to interior and atmosphere of wards. Content validity and test retest reliability were evaluated. The pain level was also measured by the visual analog scale (VAS) and scores analyzed by the statistical methods of frequency, percentage, chi-square and logistic regression. The mean of the total scores in PSQI was 8.8±4.8 and 70.8% of the patients were 'poor sleepers' (global PSQI> 5). Age and gender had no effect on the PSQI total score, but the number of roommates, type of the ward, hospitalization period, presence and severity of pain, taking sleep medication and attitude toward the overall atmosphere and interior of wards have caused deviation in scores. Sleep problems are quite frequent in medical inpatients. Pain management and modification of the ward interior and atmosphere can impact inpatients sleep quality.

  13. The influence of train running direction and track supports position on the behaviour of transition zones

    Energy Technology Data Exchange (ETDEWEB)

    Sañudo Ortega, R.; Miranda Manzanares, M.; Markine, V.; Dell' Olio, L.

    2016-07-01

    Different types of track infrastructure can be found along railway lines. Separation zones between these different types of structures are the source of a lot of problems. Transition zones on a railway line represent a gradual solution for the problems between conventional railway structure and singular structures located at different points along the line. The different nature, positioning and geometry used with the materials generate changes in the stiffness on both sides of these singular zones leading to an increase in wear and a loss of geometry, with the associated maintenance costs. This article describes the use of mathematical modelling to represent the behaviour of these zones as a function of train running direction and track supports. Available research into transition zones has not studied these separation points where high increases in load are generated for very short periods of time. Finite elements are used to model two types of track (conventional ballasted track and slab track), using a vehicle to dynamically simulate the behaviour in these zones as a function of train running direction and the position of track supports. The magnitudes analysed were the vertical stresses and the vertical displacements under the sleepers and the supports in both types of structure. The results show increased stresses at the separation zone between both structures which varied in magnitude and position depending most of track supports’ location than the train running direction. (Author)

  14. Insufficient and excessive amounts of sleep increase the risk of premature death from cardiovascular and other diseases: the Multiethnic Cohort Study.

    Science.gov (United States)

    Kim, Yeonju; Wilkens, Lynne R; Schembre, Susan M; Henderson, Brian E; Kolonel, Laurence N; Goodman, Marc T

    2013-10-01

    To explore an independent association between self-reported sleep duration and cause-specific mortality. Data were obtained from the Multiethnic Cohort Study conducted in Los Angeles and Hawaii. Among 61,936 men and 73,749 women with no history of cancer, heart attack or stroke, 19,335 deaths occurred during an average 12.9year follow-up. Shorter (≤5h/day) and longer (≥9h/day) sleepers of both sexes (vs. 7h/day) had an increased risk of all-cause and cardiovascular disease (CVD) mortality, but not of cancer mortality. Multivariable hazard ratios for CVD mortality were 1.13 (95% CI 1.00-1.28) for ≤5h/day and 1.22 (95% CI 1.09-1.35) for ≥9h/day among men; and 1.20 (95% CI 1.05-1.36) for ≤5h/day and 1.29 (95% CI 1.13-1.47) for ≥9h/day among women. This risk pattern was not heterogeneous across specific causes of CVD death among men (Phetero 0.53) or among women (Phetero 0.72). The U-shape association for all-cause and CVD mortality was observed in all five ethnic groups included in the study and by subgroups of age, smoking status, and body mass index. Insufficient or excessive amounts of sleep were associated with increased risk of mortality from CVD and other diseases in a multiethnic population. © 2013.

  15. Stress and Sleep Reactivity: A Prospective Investigation of the Stress-Diathesis Model of Insomnia

    Science.gov (United States)

    Drake, Christopher L.; Pillai, Vivek; Roth, Thomas

    2014-01-01

    Study Objectives: To prospectively assess sleep reactivity as a diathesis of insomnia, and to delineate the interaction between this diathesis and naturalistic stress in the development of insomnia among normal sleepers. Design: Longitudinal. Setting: Community-based. Participants: 2,316 adults from the Evolution of Pathways to Insomnia Cohort (EPIC) with no history of insomnia or depression (46.8 ± 13.2 y; 60% female). Interventions: None. Measurements and Results: Participants reported the number of stressful events they encountered at baseline (Time 1), as well as the level of cognitive intrusion they experienced in response to each stressor. Stressful events (OR = 1.13; P insomnia one year hence (Time 2). Intrusion mediated the effects of stressful events on risk for insomnia (P insomnia (OR = 1.78; P insomnia as a function of intrusion was significantly higher in individuals with high sleep reactivity. Trait sleep reactivity also constituted a significant risk for depression (OR = 1.67; P Insomnia at Time 2 significantly mediated this effect (P insomnia, and that it triggers insomnia by exacerbating the effects of stress-induced intrusion. Sleep reactivity is also a precipitant of depression, as mediated by insomnia. These findings support the stress-diathesis model of insomnia, while highlighting sleep reactivity as an important diathesis. Citation: Drake CL, Pillai V, Roth T. Stress and sleep reactivity: a prospective investigation of the stress-diathesis model of insomnia. SLEEP 2014;37(8):1295-1304. PMID:25083009

  16. Prevalence and risk factors of poor sleep quality among Chinese elderly in an urban community: results from the Shanghai aging study.

    Science.gov (United States)

    Luo, Jianfeng; Zhu, Guoxing; Zhao, Qianhua; Guo, Qihao; Meng, Haijiao; Hong, Zhen; Ding, Ding

    2013-01-01

    Sleep disorders causes a significant negative effect on mental and physical health, particularly among the elderly. The disease burden and risk factors of poor sleep quality of the elderly need to be verified using a validated form of measurement in urban mainland China. This study included 1086 community residents aged ≥ 60 years who completed the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI). Poor sleeper was defined by a CPSQI global score of >5. Subjects also accepted the neurological and neuropsychological assessments, including the Mini-Mental State Examination, Center for Epidemiological Studies Depression Scale, and Zung Self-Rating Anxiety Scale (ZSAS). A history of chronic diseases was confirmed by the medical records of each participant. The prevalence of poor sleep quality in this population was 41.5% (95% confidence interval (CI) = 38.6-44.5%), with a higher rate observed in elderly females (45.8% [95% CI = 41.9-49.7%]) than that in elderly males (35.8% [95% CI = 31.4-40.1%]). The prevalence rate increased with age, from 32.1% (95% CI = 27.8-36.4%) in those aged 60-69 years to 52.5% (95% CI = 45.9-59.1%) in those aged ≥ 80 years (p value for trendsleep quality. Poor sleep quality is highly prevalent among elderly Chinese residents in urban Shanghai. Growing attention and comprehensive countermeasures involving psycho-social and personal activities might alleviate the sleep problem in the elderly.

  17. Sleep characteristics and cardiovascular events in a large Swedish cohort.

    Science.gov (United States)

    Westerlund, Anna; Bellocco, Rino; Sundström, Johan; Adami, Hans-Olov; Åkerstedt, Torbjörn; Trolle Lagerros, Ylva

    2013-06-01

    Limited evidence suggests that the association between sleep duration and cardiovascular events is strongest in individuals who also report sleep disturbances. We investigated sleep duration and insomnia symptoms in relation to incident cardiovascular events in the Swedish National March Cohort comprising 41,192 adults. Habitual sleep duration and difficulty falling asleep, difficulty maintaining sleep, early morning awakening, and nonrestorative sleep were self-reported in 1997. During 13.2 years of follow-up, we identified 4,031 events (myocardial infarction, stroke, heart failure, or death from cardiovascular disease) in the Swedish National Patient Register and the Cause of Death Register. After adjustment for potential confounders, short sleep duration (≤5 h) was associated with slightly increased risks of overall cardiovascular events and, specifically, myocardial infarction: hazard ratio, HR (95% confidence interval) 1.24 (1.06-1.44) and 1.42 (1.15-1.76), respectively. These HRs were attenuated as we included BMI, depressive symptoms and other relevant covariates in our analysis. Insomnia symptoms per se were unrelated to risk. However, in a joint analysis, there was some evidence that short sleepers who reported frequent insomnia symptoms had the highest HRs (1.26-1.39) of overall cardiovascular events. Short sleep or insomnia symptoms without the other conferred no increased risk. Our results suggest that symptoms of sleep disturbance should be taken into account when assessing the association between short sleep and cardiovascular disease.

  18. Anaesthesia in Dental Medicine with Local Infiltrative Anaesthetic Technique Versus Diploe Anaesthesia Delivery Systems: Efficacy and Behaviour, an Experimental Study.

    Science.gov (United States)

    Marques-Ferreira, Manuel; Carrilho, Eunice; Paulo, Siri; Carrilho, Teresa; Pedro Figueiredo, José; Macedo, Ricardo

    2017-12-29

    This study aimed to compare the analgesic efficacy and the influence of local infiltrative anesthesia techniques, with diploe anesthesia, on the cardiac rhythmMaterial and Methods: We selected 32 healthy volunteers who were given both anaesthetic techniques on tooth 1.4 (0.45 mL of lidocaine with adrenaline, 1:80 000). In the first phase, the volunteers underwent periapical infiltrative anaesthesia. In the second phase, diploe anaesthesia was performed with a QuickSleeper® device. The parameters analysed were pulp response to the electrical test and heart rate of the participants. These parameters were evaluated on five different occasions: before anaesthesia (t0), immediately after anaesthesia (t1), 15 minutes later (t15), 30 minutes later (t30) and 60 minutes later (t60). Statistical analysis of the data was performed using SPSS 2.0 software, with α = 0.05. With the diploe anaesthesia, a level of analgesia was obtained faster. There was a slight increase in heart rate soon after administration of diploe anaesthesia, which stabilized after t15 of the procedure. This technique still proved to be painless. Diploe anaesthesia demonstrated better results in terms of analgesia than the infiltrative anaesthesia. It has been reported to be easy, safe and an effective procedure that allows anaesthesia in almost all clinical situations. This approach may offer particular advantages for endodontic therapy, providing greater comfort for the patient.

  19. Prevalence and risk factors of monosymptomatic nocturnal enuresis in Turkish children

    Directory of Open Access Journals (Sweden)

    Secil Ozkan

    2010-01-01

    Full Text Available Objectives : To determine the prevalence of primary monosymptomatic nocturnal enuresis (PMNE and assess risk factors that can cause this disease. Methods : After the determination of 15 primary schools in the provincial center of Ankara, questionnaires were given to 15,150 students to be answered by their parents. Detailed urologic history was obtained and physical examination applied to the students whose parents answered the questionnaire. After excluding children with polysymptomatic NE, 14060 questionnaires of MNE patients were evaluated. Demographic features with social and medical history of students and their parents, general approach of family to the children, school success of the students and general behavioral attitudes, method of toilet training and the presence of nocturnal enuresis were questioned. Results : MNE was determined in 9.0% (n: 1266 of the students and nocturnal enuresis frequency was higher in boys than girls (P< 0.05. Univariate analysis revealed gender, method of toilet training, sleep problems, school success, and general approach of the family to children and general behavioral attitudes of the children as significant factors. In logistic regression analysis; age, male gender, toilette training with threatening method, deep sleeper, sleep walking, being introverted and shy, significantly increases the risk of nocturnal enuresis. Conclusions : The current study suggests that the methods of toilet training are extremely important to prevent bedwetting and behavioral disorders due to enuresis. Parents should be well-informed about the appropriate toilet training method.

  20. Associations of Short Sleep and Shift Work Status with Hypertension among Black and White Americans

    Directory of Open Access Journals (Sweden)

    Mirnova E. Ceïde

    2015-01-01

    Full Text Available Objective. The purpose of this study was to investigate whether short sleepers (<6 hrs who worked the non-day-shift were at greater likelihood of reporting hypertension and if these associations varied by individuals’ ethnicity. Methods. Analysis was based on the 2010 National Health Interview Survey (NHIS. A total of 59,199 American adults provided valid data for the present analyses (mean age = 46.2±17.7 years; 51.5% were female. Respondents provided work schedule and estimated habitual sleep durations as well as self-report of chronic conditions. Results. Of the sample, 30.8% reported a diagnosis of hypertension, 79.1% reported daytime shift work, 11.0% reported rotating shift work, and 4.0% reported night shift work. Logistic regression analysis showed that shift work was significantly associated with hypertension among Blacks [OR = 1.35, CI: 1.06–1.72. P<0.05], but not among Whites [OR = 1.01, CI: 0.85–1.20, NS]. Black shift workers sleeping less than 6 hours had significantly increased odds of reporting hypertension [OR = 1.81, CI: 1.29–2.54, P<0.01], while their White counterparts did not [OR = 1.17, CI: 0.90–1.52, NS]. Conclusions. Findings suggest that Black Americans working the non-day-shift especially with short sleep duration have increased odds of reporting hypertension.

  1. Insomnia and sleep misperception.

    Science.gov (United States)

    Bastien, C H; Ceklic, T; St-Hilaire, P; Desmarais, F; Pérusse, A D; Lefrançois, J; Pedneault-Drolet, M

    2014-10-01

    Sleep misperception is often observed in insomnia individuals (INS). The extent of misperception varies between different types of INS. The following paper comprised sections which will be aimed at studying the sleep EEG and compares it to subjective reports of sleep in individuals suffering from either psychophysiological insomnia or paradoxical insomnia and good sleeper controls. The EEG can be studied without any intervention (thus using the raw data) via either PSG or fine quantitative EEG analyses (power spectral analysis [PSA]), identifying EEG patterns as in the case of cyclic alternating patterns (CAPs) or by decorticating the EEG while scoring the different transient or phasic events (K-Complexes or sleep spindles). One can also act on the on-going EEG by delivering stimuli so to study their impact on cortical measures as in the case of event-related potential studies (ERPs). From the paucity of studies available using these different techniques, a general conclusion can be reached: sleep misperception is not an easy phenomenon to quantify and its clinical value is not well recognized. Still, while none of the techniques or EEG measures defined in the paper is available and/or recommended to diagnose insomnia, ERPs might be the most indicated technique to study hyperarousal and sleep quality in different types of INS. More research shall also be dedicated to EEG patterns and transient phasic events as these EEG scoring techniques can offer a unique insight of sleep misperception. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  2. Minimal olfactory perception during sleep: why odor alarms will not work for humans.

    Science.gov (United States)

    Carskadon, Mary A; Herz, Rachel S

    2004-05-01

    To examine olfactory arousal threshold during sleep in comparison to an auditory tone. On night 1, participants rated odor intensity when awake and experienced olfactory stimuli during stage 1 sleep. Night 2 involved stage 2, stage 4, and rapid-eye-movement (REM) sleep trials using the "staircase" threshold-detection method. Electroencephalogram, electrooculogram, electromyogram, electrocardiogram, and respiration were recorded along with behavioral response. An 800-Hz tone was given on trials when odors failed to arouse. Participants slept in individual rooms. Stimulus-delivery systems were operated from a separate room, where an experimenter observed physiologic recordings and behavioral responses. Three healthy men and 3 women aged 20 to 25 years (mean, 22 years). Two odorants, peppermint and pyridine, at 4 concentrations were presented through nasal cannulas using an air-dilution olfactometer. Tones were played over a speaker. Behavioral (button press and oral) responses, electroencephalographic activation, and changes in breathing and heart rate were assessed. Participants responded to odors on 92% of stage 1 sleep trials. Peppermint was ineffective in stages 2, 4, and REM sleep. Pyridine produced behavioral threshold on 45% of stage 2 trials, none in stage 4, and one third of REM sleep trials. Tones were effective on at least 75% of trials. Heart rate increased significantly only following behavioral responses to odors or tones across sleep stages. The data indicate that human olfaction is not reliably capable of alerting a sleeper.

  3. Period 3 gene polymorphism and sleep adaptation to stressful urban environments.

    Science.gov (United States)

    Anderson, Maxwell R; Akeeb, Ameenat; Lavela, Joseph; Chen, Yuanxiu; Mellman, Thomas A

    2017-02-01

    This study's objective was to investigate the relationship between a variable-number tandem-repeat (VNTR) Period 3 gene (PER3) polymorphism and sleep adaptation to stressful urban environments. Seventy-five (49 female) African American participants (ages 18-35 years) living in neighbourhoods with high rates of violent crime were selected for the study based on converging criteria for good or poor sleep. Categorization of sleep quality was based on the Insomnia Severity Index (ISI), estimates of typical sleep duration and sleep efficiency. Other assessments included the Fear of Sleep Index (FOSI) and City Stress Inventory (CSI). Whole blood DNA was analysed for the 4 and 5 VNTR alleles using polymerase chain reaction (PCR) and restrictive enzyme digestion. Fifty-seven per cent of those who were homo- or heterozygous for the 4-repeat allele were poor sleepers versus 25% of those homozygous for the 5-repeat allele; χ 2  = 4.17, P = 0.041. In a logistic regression model with all the variables with significant bivariate relationships to sleep quality group, FOSI was the only significant predictor (χ 2  = 5.68, P = 0.017). FOSI scores were higher among those with the 4-repeat allele (t = 2.66, P = 0.013). The PER3 4 and 5 VNTR polymorphisms appear to influence sensitivity to the effects of stressful urban environments on sleep. While FOSI was the only variable associated independently with sleep quality category, the candidate vulnerability allele was also associated with greater 'fear of sleep'. © 2016 European Sleep Research Society.

  4. [Light and blindness in ancient Egypt].

    Science.gov (United States)

    Maria Rosso, Ana

    2010-01-01

    In Ancient Egypt, light and fire, which were closely related to the Sun God Ra, were the sources of life and well-being, while the dark meant danger and death. Similar to death, darkness drops on human beings in deep sleep and they enter a space inhabited by shadows. Dreams were believed to reveal an unknown world, to give the sleeper a glimpse into the future. Vision attracts distant objects and their light, on the other hand, can hurt the eyes like a burning flame. Eyes were the most important organ in Egyptian thought, as they allowed perception of the real world. Their importance has been immortalised in the myth of the Eye of Horus that explains the role of either eye. One represents the moonlight, which disperses the darkness of the night, and the other represents the sunshine, which creates life, and both could also represents the power of human intellect. Blindness, in turn, congenital or disease-related, was considered a divine punishment. A man, thus handicapped, would sink in a state of uncertainty and darkness. To protect the eyes from blindness, people used drops and ointments, which were believed to chase away all kinds of insects and demons that threatened with a variety of eye infections. Egyptian eye doctors or physicians, carried a special kit that contained green chrysocolla and a black kohl makeup, highly appreciated as prophylaxis because they personified Osiris' humours or body fluids. These products were offered to Gods to restore the brightness of divine glance and incite sun and moon to spread their beneficial light.

  5. The influence of sleep duration and sleep-related symptoms on baseline neurocognitive performance among male and female high school athletes.

    Science.gov (United States)

    Sufrinko, Alicia; Johnson, Eric W; Henry, Luke C

    2016-05-01

    Typically, the effects of sleep duration on cognition are examined in isolation. This study examined the effects of restricted sleep and related symptoms on neurocognitive performance. Baseline Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) and postconcussion symptom scale (PCSS) were administered to athletes (N = 7,150) ages 14-17 (M = 15.26, SD = 1.09) prior to sport participation. Three groups of athletes were derived from total sleep duration: sleep restriction (≤5 hours), typical sleep (5.5-8.5 hours), and optimal sleep (≥9 hours). A MANCOVA (age and sex as covariates) was conducted to examine differences across ImPACT/PCSS. Follow-up MANOVA compared ImPACT/PCSS performance among symptomatic (e.g., trouble falling asleep, sleeping less than usual) adolescents from the sleep restriction group (n = 78) with asymptomatic optimal sleepers (n = 99). A dose-response effect of sleep duration on ImPACT performance and PCSS was replicated (Wilk's λ = .98, F2,7145 = 17.25, p sleep restricted adolescents (n = 78) had poorer neurocognitive performance: verbal memory, F = 11.60, p = .001, visual memory, F = 6.57, p = .01, visual motor speed, F = 6.19, p = .01, and reaction time (RT), F = 5.21, p = .02, compared to demographically matched controls (n = 99). Girls in the sleep problem group performed worse on RT (p = .024). Examining the combination of sleep-related symptoms and reduced sleep duration effectively identified adolescents at risk for poor neurocognitive performance than sleep duration alone. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  6. Changes in Sleep Duration During Transition to Statutory Retirement: A Longitudinal Cohort Study.

    Science.gov (United States)

    Myllyntausta, Saana; Salo, Paula; Kronholm, Erkki; Aalto, Ville; Kivimäki, Mika; Vahtera, Jussi; Stenholm, Sari

    2017-07-01

    This study examined whether sleep duration changes during the transition from full-time work to statutory retirement and, if this were the case, which preretirement factors, including sociodemographic, work, lifestyle, and health factors, predict these changes. Data from repeated surveys of the Finnish Public Sector study, linked to records of retirement, were used. The study population consisted of 5785 participants who retired on a statutory basis in 2000-2011 and who had responded to surveys on sleep duration at least once immediately before and after their retirement (mean number of repeat study waves 3.6). Linear regression analyses with generalized estimating equations were used to examine changes in sleep duration around retirement. Before retirement there was a slight decrease in sleep duration. During the 4-year retirement transition, sleep duration increased from 7 hours 0 minutes (95% confidence interval [CI] 6 hours 54 minutes to 7 hours 6 minutes) to 7 hours and 22 minutes (95% CI 7 hours 16 minutes to 7 hours 27 minutes); thus, mean increase being 22 minutes. Increase in sleep duration was greatest in those who were short sleepers, heavy drinkers, or had sleep difficulties. After the retirement transition, sleep duration remained at approximately the same level, as no significant changes were observed. This longitudinal study suggests that transition from full-time work to statutory retirement is associated with an increase in sleep duration. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  7. ASSOCIATION BETWEEN INFANT NIGHTTIME-SLEEP LOCATION AND ATTACHMENT SECURITY: NO EASY VERDICT.

    Science.gov (United States)

    Mileva-Seitz, Viara R; Luijk, Maartje P C M; van Ijzendoorn, Marinus H; Bakermans-Kranenburg, Marian J; Jaddoe, Vincent W V; Hofman, Albert; Verhulst, Frank C; Tiemeier, Henning

    2016-01-01

    We tested whether mother-infant bed-sharing is associated with increased secure infant-mother attachment, a previously unexplored association. Frequency of bed-sharing and mothers' nighttime comforting measures at 2 months were assessed with questionnaires in 550 Caucasian mothers from a population-based cohort. Attachment security was assessed with the Strange Situation Procedure (M.D.S. Ainsworth, M.C. Blehar, E. Waters, & S. Wall, 1978) at 14 months. When using a dichotomous variable, "never bed-sharing" (solitary sleepers) versus "any bed-sharing," the relative risk of being classified as insecurely attached for solitary-sleeping infants (vs. bed-sharers) was 1.21 (95% confidence interval: 1.05-1.40). In multivariate models, solitary sleeping was associated with greater odds of insecure attachment, adjusted odds ratio (OR): 1.50, 95% CI = 1.02-2.20) and, in particular, with greater odds of resistant attachment, adjusted OR = 1.74, 95% CI = 1.10-2.76); and with a lower attachment security score, β = -0.12, t(495) = -2.61, p = .009. However, we found no evidence of a dose-response association between bed-sharing and secure attachment when using a trichotomous bed-sharing variable based on frequency of bed-sharing. Our findings demonstrate some evidence that solitary sleeping is associated with insecure attachment. However, the lack of a dose-response association suggests that further experimental study is necessary before accepting common notions that sharing a bed leads to children who are better or not better adjusted. © 2015 Michigan Association for Infant Mental Health.

  8. ASSESSING THE SLEEP QUALITY AND DEPRESSION-ANXIETY-STRESS IN IRRITABLE BOWEL SYNDROME PATIENTS

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    Nadieh BANIASADI

    2017-02-01

    Full Text Available ABSTRACT BACKGROUND Irritable bowel syndrome (IBS is one of the most common functional gastrointestinal disorders with chronic abdominal pain and altered bowel habit without any organic reason. Sleep disorders may be associated to IBS. OBJECTIVE We aimed to assess sleep disturbances and depression-anxiety-stress in IBS patients. METHODS In this analytical cross sectional study from November 2013 to May 2014, A total of 123 IBS patients were recruited by simple random sampling. IBS was diagnosed using ROME-III criteria. Demographic and basic data were driven from all patients then Pittsburg Sleep Quality Index questionnaire was utilized to estimate sleep quality and DASS (depression anxiety stress scale questionnaire was filled out for depression, anxiety and stress. RESULTS The mean age of patients was 29±9, where 48 cases (39% were male. Twelve cases (10% had a background disease. Types of IBS in patients were included 38% diarrhea, 42% constipation and 20% mixed. From all IBS patients 87 (71% cases had depression, 97 (79% patients stress, 94 (76% patients had anxiety. Seventy-six (62% cases of IBS patients had poor sleep quality. Simultaneously employing predictors demonstrate that gender, background disease, and type of IBS did not statistically significant. On the other hand, depression (P=0.034, OR=2.35, anxiety (P=0.011, OR=3.022, and stress (P=0.029, OR=2.77 were significantly effect on sleep quality in poor sleepers. CONCLUSION Many of IBS patients is suffering from poor sleep quality. It seems that sleep disorder should be considered and treated in this patients.

  9. Relationship of Sleep Duration with Sociodemographic Characteristics, Lifestyle, Mental Health, and Chronic Diseases in a Large Chinese Adult Population.

    Science.gov (United States)

    Wang, Shibin; Li, Bo; Wu, Yanhua; Ungvari, Gabor S; Ng, Chee H; Fu, Yingli; Kou, Changgui; Yu, Yaqin; Sun, Hong-Qiang; Xiang, Yu-Tao

    2017-03-15

    Pattern of sleep duration and its correlates have rarely been reported in China. This study examined the sleep duration and its relationship with sociodemographic variables, lifestyle, mental health, and chronic diseases in a large Chinese adult population. This cross-sectional study used multistage stratified cluster sampling. A total of 17,320 participants from Jilin province were selected and interviewed using standardized assessment tools. Basic socio-demographic and clinical data were collected. Sleep duration was classified as short ( 9 h per day) and medium sleep (7-9 h per day). The mean age of the sample was 42.60 ± 10.60 y, with 51.4% being female. The mean sleep duration was 7.31 ± 1.44 h. Short and long sleepers accounted for 30.9% and 6.9% of the sample, respectively. Multinomial logistic regression analysis revealed that older age, current smoking, irregular meal pattern, lack of physical exercise, poor mental health, and chronic diseases or multimorbidity were positively associated with short sleep. Being married and living in rural areas were, however, negatively associated with short sleep. In addition, living in rural area, current smoking, current alcohol use and lack of physical exercise were positively associated with long sleep, while older age and lower education were negatively associated with long sleep. Given the high frequency of short sleep and its negative effect on health, health professionals should pay more attention to sleep patterns in general health care. Nationwide epidemiologic surveys in China are needed to further explore the relationship between sleep duration and health. © 2017 American Academy of Sleep Medicine

  10. Evaluation of the wood CCA preservative treatment process of Eucalyptus (Eucaliptus ssp) by X-ray fluorescence technique

    International Nuclear Information System (INIS)

    Pereira Junior, Sergio Matias; Salvador, Vera Lucia Ribeiro; Sato, Ivone Mulako

    2013-01-01

    Brazil produces around 1,2 mi m 3 of treated wood to meet the annual demand of railway, electric, rural and construction sectors. The treated woods used for poles, sleepers, fence posts and plywoods should be according to Brazilian norms requirements. The most used wood species are eucalyptus (Eucaliptus ssp)and pine (Pinus ssp). The most wood preservative products used in Brazil are CCA (Chromated Copper Arsenate) and CCB (Copper Chromium and Boron Salt). The analytical methods, such as Flame Atomic Absorption Spectrometry (FAAS) and Plasma Inductively Coupled Optical Emission Spectrometry (ICPOES) have been used for the evaluation of those treatment processes. In this work, the sapwood sample was obtained from eucalyptus trees (Eucaliptus ssp) obtained from Minas Gerais State, Brazil, cut plantation areas. Sawdust sapwood sample was grounded and submitted to different additions of CCA solutions (0.2, 0.7, 1.3, 2.3, 3.6, 6.3, 11.7and17.9 kg m -3 ). Power and pressed pellets sapwood samples, analyzed by EDXRFS, showed a good linear relation (r 2 >0.99) between the characteristic intensity fluorescent lines (CuΚα, CrΚαand AsΚΒ) and their concentration, also, showed adequate sensitivity (LQ -1 ) for Cu, Cr and As determination in treated woods. Cu, Cr and As were determined in powdered sawdust samples by FAA spectrometry, using the AWPA A11-93 standard method; the relation between the CCA retention and their concentration showed a lower linear relation than EDXRFS; the FAAS spreading result could be attributed to laboratorial CCA addition process. (author)

  11. Climatic and geomorphic controls on low flow hydrograph recession

    Science.gov (United States)

    Chandler, D. G.; Daley, M.; Kasaee Roodsari, B.; Shaw, S. B.; McNamara, J.

    2017-12-01

    Large scale operational hydrologic models should be capable of predicting seasonally low flow and stream intermittency as well as peak flow and inundation. We contrast examples of controls on low flow exerted by geomorphic and climatic setting at small catchment study sites in the Northeast and Northwest of the USA to indicate differences in hydrologic processes. Both regions accumulate winter snowpack and have an extended spring freshet, but the Reynolds Creek CZO and Dry Creek Experimental Watershed (both in Idaho mountains) experience a protracted summer drought, with occasional storms whereas precipitation free periods greater than five days are uncommon in the hilly Sleepers River (Vermont), and Yellow Barn State Forest (New York) and at Ley Creek, on a glacial plain (New York). At both Dry Creek and Reynolds Creek, headwater stream flow direction was transverse to groundwater, and below field capacity discharge was well related to either the ground water surface or corresponded to inversion of the hydraulic gradient over the depth of the soil. At all sites except Ley Creek, the headwaters became intermittent as the main tributary discharge declined, often disconnecting the surface source springs and seeps from the valley bottom stream. At the Idaho sites recession analysis for main stem was further complicated by consumptive use for irrigation and domestic wells. Modeling the recession characteristics of these various settings and across stream orders results in a variety of exponent values for power law scaling approaches that indicate the importance of site context for modeling low flow.

  12. Use of color maps and wavelet coherence to discern seasonal and interannual climate influences on streamflow variability in northern catchments

    Science.gov (United States)

    Carey, Sean K.; Tetzlaff, Doerthe; Buttle, Jim; Laudon, Hjalmar; McDonnell, Jeff; McGuire, Kevin; Seibert, Jan; Soulsby, Chris; Shanley, Jamie

    2013-10-01

    The higher midlatitudes of the northern hemisphere are particularly sensitive to change due to the important role the 0°C isotherm plays in the phase of precipitation and intermediate storage as snow. An international intercatchment comparison program called North-Watch seeks to improve our understanding of the sensitivity of northern catchments to change by examining their hydrological and biogeochemical variability and response. Here eight North-Watch catchments located in Sweden (Krycklan), Scotland (Girnock and Strontian), the United States (Sleepers River, Hubbard Brook, and HJ Andrews), and Canada (Dorset and Wolf Creek) with 10 continuous years of daily precipitation and runoff data were selected to assess daily to seasonal coupling of precipitation (P) and runoff (Q) using wavelet coherency, and to explore the patterns and scales of variability in streamflow using color maps. Wavelet coherency revealed that P and Q were decoupled in catchments with cold winters, yet were strongly coupled during and immediately following the spring snowmelt freshet. In all catchments, coupling at shorter time scales occurred during wet periods when the catchment was responsive and storage deficits were small. At longer time scales, coupling reflected coherence between seasonal cycles, being enhanced at sites with enhanced seasonality in P. Color maps were applied as an alternative method to identify patterns and scales of flow variability. Seasonal versus transient flow variability was identified along with the persistence of that variability on influencing the flow regime. While exploratory in nature, this intercomparison exercise highlights the importance of climate and the 0°C isotherm on the functioning of northern catchments.

  13. Development of Viscoelastic Multi-Body Simulation and Impact Response Analysis of a Ballasted Railway Track under Cyclic Loading

    Directory of Open Access Journals (Sweden)

    Daisuke Nishiura

    2017-06-01

    Full Text Available Simulation of a large number of deformable bodies is often difficult because complex high-level modeling is required to address both multi-body contact and viscoelastic deformation. This necessitates the combined use of a discrete element method (DEM and a finite element method (FEM. In this study, a quadruple discrete element method (QDEM was developed for dynamic analysis of viscoelastic materials using a simpler algorithm compared to the standard FEM. QDEM easily incorporates the contact algorithm used in DEM. As the first step toward multi-body simulation, the fundamental performance of QDEM was investigated for viscoelastic analysis. The amplitude and frequency of cantilever elastic vibration were nearly equal to those obtained by the standard FEM. A comparison of creep recovery tests with an analytical solution showed good agreement between them. In addition, good correlation between the attenuation degree and the real physical viscosity was confirmed for viscoelastic vibration analysis. Therefore, the high accuracy of QDEM in the fundamental analysis of infinitesimal viscoelastic deformations was verified. Finally, the impact response of a ballast and sleeper under cyclic loading on a railway track was analyzed using QDEM as an application of deformable multi-body dynamics. The results showed that the vibration of the ballasted track was qualitatively in good agreement with the actual measurements. Moreover, the ballast layer with high friction reduced the ballasted track deterioration. This study suggests that QDEM, as an alternative to DEM and FEM, can provide deeper insights into the contact dynamics of a large number of deformable bodies.

  14. Racial disparities in short sleep duration by occupation and industry.

    Science.gov (United States)

    Jackson, Chandra L; Redline, Susan; Kawachi, Ichiro; Williams, Michelle A; Hu, Frank B

    2013-11-01

    Short sleep duration, which is associated with increased morbidity and mortality, has been shown to vary by occupation and industry, but few studies have investigated differences between black and white populations. By using data from a nationally representative sample of US adult short sleepers (n = 41,088) in the National Health Interview Survey in 2004-2011, we estimated prevalence ratios for short sleep duration in blacks compared with whites for each of 8 industry categories by using adjusted Poisson regression models with robust variance. Participants' mean age was 47 years; 50% were women and 13% were black. Blacks were more likely to report short sleep duration than whites (37% vs. 28%), and the black-white disparity was widest among those who held professional occupations. Adjusted short sleep duration was more prevalent in blacks than whites in the following industry categories: finance/information/real estate (prevalence ratio (PR) = 1.44, 95% confidence interval (CI): 1.30, 1.59); professional/administrative/management (PR = 1.30, 95% CI: 1.18, 1.44); educational services (PR = 1.39, 95% CI: 1.25, 1.54); public administration/arts/other services (PR = 1.30, 95% CI: 1.21, 1.41); health care/social assistance (PR = 1.23, 95% CI: 1.14, 1.32); and manufacturing/construction (PR = 1.14, 95% CI: 1.07, 1.20). Short sleep generally increased with increasing professional responsibility within a given industry among blacks but decreased with increasing professional roles among whites. Our results suggest the need for further investigation of racial/ethnic differences in the work-sleep relationship.

  15. ASSESSING THE SLEEP QUALITY AND DEPRESSION-ANXIETY-STRESS IN IRRITABLE BOWEL SYNDROME PATIENTS.

    Science.gov (United States)

    Baniasadi, Nadieh; Dehesh, Mohammad Moein; Mohebbi, Elham; Hayatbakhsh Abbasi, Mahdy; Oghabian, Zohreh

    2017-01-01

    Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders with chronic abdominal pain and altered bowel habit without any organic reason. Sleep disorders may be associated to IBS. We aimed to assess sleep disturbances and depression-anxiety-stress in IBS patients. In this analytical cross sectional study from November 2013 to May 2014, A total of 123 IBS patients were recruited by simple random sampling. IBS was diagnosed using ROME-III criteria. Demographic and basic data were driven from all patients then Pittsburg Sleep Quality Index questionnaire was utilized to estimate sleep quality and DASS (depression anxiety stress scale) questionnaire was filled out for depression, anxiety and stress. The mean age of patients was 29±9, where 48 cases (39%) were male. Twelve cases (10%) had a background disease. Types of IBS in patients were included 38% diarrhea, 42% constipation and 20% mixed. From all IBS patients 87 (71%) cases had depression, 97 (79%) patients stress, 94 (76%) patients had anxiety. Seventy-six (62%) cases of IBS patients had poor sleep quality. Simultaneously employing predictors demonstrate that gender, background disease, and type of IBS did not statistically significant. On the other hand, depression (P=0.034, OR=2.35), anxiety (P=0.011, OR=3.022), and stress (P=0.029, OR=2.77) were significantly effect on sleep quality in poor sleepers. Many of IBS patients is suffering from poor sleep quality. It seems that sleep disorder should be considered and treated in this patients.

  16. Determination of chromated copper arsenate (CCA) in treated wood of Eucalyptus

    International Nuclear Information System (INIS)

    Parreira, Paulo S.; Vendrametto, Guilherme R.; Cunha, Magda E.T.

    2009-01-01

    This work deals with the possible application of a portable energy dispersive handmade system (PXRF-LFNA-02) for the determination of Chromium, Copper and Arsenic in the preservative solution used to protect commercial wood of Eucalyptus, which are employed as wood fence, posts, contention fences, railroad sleepers, etc. It was prepared five body-of-proof made of eucalyptus alburnum with different concentrations for each element varying from 0.0061 to 0.0180 (g/g) for CrO 3 , 0.0024 to 0.0070 (g/g) for CuO and 0.0044 to 0.0129 (g/g) for As 2 O 5 . Four of them were used for calibration curves and one used as reference sample. It was used a commercial CCA (Chromated Copper Arsenate ) solution to prepare the samples. The results show a good linear regression between concentrations and X-rays intensities, after applied the multiple linear regression methodology for interelemental corrections. The values obtained with this methodology were 3.01(kg/m 3 ), 1.18 (kg/m 3 ) e 2.21 (kg/m 3 ) for CrO 3 , CuO and As 2 O 5 , respectively, while the nominal values are 2.90 (kg/m 3 ) for CrO 3 , 1.13 (kg/m 3 ) for CuO and 2.07 (kg/m 3 ) for As 2 O 5 . The ED-XRF (Energy Dispersive X-Rays Fluorescence) is a well established technique with high-speed of analytical procedure and its portable configuration allowing a multielemental, simultaneous and non destructive analyses besides in situ application. (author)

  17. Naturalistic Effects of Five Days of Bedtime Caffeine Use on Sleep, Next-Day Cognitive Performance, and Mood

    Science.gov (United States)

    Tiplady, Brian; Priestley, Caroline M.; Rogers, Peter J.

    2014-01-01

    Background: Disruptive effects of caffeine on sleep have previously been reported, although measures of next-day mood and performance have rarely been included. The present study aims to evaluate the effects of caffeine on sleep and associated next-day effects in a naturalistic field setting. Methods: Nineteen participants (daily caffeine intake 0–141 mg), assessed as good sleepers, took part in a randomized, placebo-controlled, double-blind, 2-week crossover study to assess the effects of bedtime caffeine use (250 mg) on sleep and next-day cognitive performance and mood, which were assessed on a mobile phone in the morning and afternoon. Sleep was assessed objectively (actiwatch) and subjectively (sleep diary). Results: Caffeine's effects on sleep were largely restricted to the first day of administration, with actigraphically measured reduced sleep efficiency, increased activity score and fragmentation index, decreased self-rated sleep quality, and an increased occurrence of participants waking early; only decreased sleep efficiency remained over the week. Effects on next-day performance and mood were evident over the whole week, although despite disrupting sleep, accuracy on a working memory task was higher after caffeine than placebo administration. Conclusions: Caffeine disrupted sleep, although when assessing next-day performance, which may have been affected by the presence of residual caffeine, performance appeared better after caffeine compared to placebo, although this was most likely due to prevention of the effects of overnight withdrawal from caffeine rather than representing a net benefit. Furthermore, partial tolerance developed to the effects of caffeine on sleep. PMID:24868491

  18. A Qualitative Assessment of the Acceptability of Smartphone Applications for Improving Sleep Behaviors in Low-Income and Minority Adolescents.

    Science.gov (United States)

    Quante, Mirja; Khandpur, Neha; Kontos, Emily Z; Bakker, Jessie P; Owens, Judith A; Redline, Susan

    2018-02-05

    Daily behaviors such as sleep can be targeted by smartphone app-based interventions, with potential utility among young people of minority ethnic backgrounds who commonly access smartphone devices and are short sleepers. There is a need to understand the acceptability and youth's readiness to use apps to improve sleep, and to identify desired app components that would motivate engagement. We conducted three focus group discussions (N = 27 total, age 14-18 years) within low- and middle-income ethnically diverse Boston neighborhoods. We also interviewed 10 participants who provided specific feedback on two commercially available sleep-promoting apps, one of which they had used on their smartphone preceding the interviews. All focus group discussions and interviews were audio-recorded, transcribed, and thematically analyzed. We identified several barriers to adoption of sleep hygiene interventions, namely reluctance to follow scheduled sleep routines on weekends and concern about "parting" with electronics at bedtime. Participants were intrigued by the idea of adopting an app-based sleep intervention, but were skeptical that they could successfully adopt sleep hygiene practices, and were more interested in making changes on school days than on weekends. Nonetheless, the overall feedback on two commercial sleep apps, neither targeted at youth, was positive, with a good adherence and engagement rate, and perceived health benefits. Our findings highlight the need to adapt sleep hygiene recommendations to targeted populations, considering preferences and social and cultural contextual factors. Our research also underscores the importance of the platform, setting, and messenger when delivering health information to adolescents.

  19. Respiratory Symptoms, Sleep, and Quality of Life in Patients With Advanced Lung Cancer.

    Science.gov (United States)

    Lou, Vivian W Q; Chen, Elaine J; Jian, Hong; Zhou, Zhen; Zhu, Jingfen; Li, Guohong; He, Yaping

    2017-02-01

    Maintenance of quality of life and symptom management are important in lung cancer therapy. To the author's knowledge, the interplay of respiratory symptoms and sleep disturbance in affecting quality of life in advanced lung cancer remains unexamined. The study was designed to examine the relationships among respiratory symptoms, sleep disturbance, and quality of life in patients with advanced lung cancer. A total of 128 patients with advanced lung cancer (from chest oncology inpatient-units in Shanghai, China) participated in the study. They completed two questionnaires: the Functional Assessment of Cancer Therapy-Lung and the Pittsburgh Sleep Quality Index. Symptomatic breathing difficulty, coughing, shortness of breath, and tightness in the chest were reported in 78.1%, 70.3%, 60.9%, and 60.2% of the patients, respectively. Sleep disturbance affected 62.5% of the patients. The patients with severe respiratory symptoms were more likely to be poor sleepers and to have a lower quality of life. After the covariates were controlled for, regression analysis showed that respiratory symptoms and sleep disturbance were significant indicators of quality of life. In addition, some of the effect of the respiratory symptoms on quality of life was mediated by sleep disturbance. Respiratory symptoms and sleep disturbance were common in the advanced lung cancer patients and had a negative impact on their quality of life; sleep disturbance may mediate the relationship between respiratory symptoms and quality of life. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  20. Gender Differences in Regional Brain Activity in Patients with Chronic Primary Insomnia: Evidence from a Resting-State fMRI Study.

    Science.gov (United States)

    Dai, Xi-Jian; Nie, Xiao; Liu, Xuming; Pei, Li; Jiang, Jian; Peng, De-chang; Gong, Hong-Han; Zeng, Xian-Jun; Wáng, Yì-Xiáng J; Zhan, Yang

    2016-03-01

    To explore the regional brain activities in patients with chronic primary insomnia (PCPIs) and their sex differences. Forty-two PCPIs (27 females, 15 males) and 42 good sleepers (GSs; 24 females, 18 males) were recruited. Six PCPIs (3 males, 3 females) were scanned twice by MRI to examine the test-retest reliability. Amplitude of low frequency fluctuation (ALFF) method was used to assess the local brain features. The mean signal values of the different ALFF areas were analyzed with a receiver operating characteristic (ROC) curve. Simple linear regression analysis was performed to investigate the relationships between clinical features and different brain areas. Both female and male PCPIs showed higher ALFF in the temporal lobe and occipital lobe, especially in female PCPIs. Female PCPIs had lower ALFF in the bilateral cerebellum posterior lobe, left dorsolateral prefrontal cortex, and bilateral limbic lobe; however, male PCPIs showed lower ALFF in the left occipital gyrus. The mean signal value of the cerebellum in female PCPIs showed negative correlations with negative emotions. Compared with male PCPIs, female PCPIs showed higher ALFF in the bilateral middle temporal gyrus and lower ALFF in the left limbic lobe. The different areas showed high test-retest stability (Clusters of contiguous volumes ≥ 1080 mm(3) with an intraclass correlation coefficient ≥ 0.80) and high degree of sensitivity and specificity. Female PCPIs showed more regional brain differences with higher and lower ALFF responses than male PCPIs. However, they shared analogous excessive hyperarousal mechanism and wide variations in aberrant brain areas. © 2016 American Academy of Sleep Medicine.

  1. Association of academic stress with sleeping difficulties in medical students of a Pakistani medical school: a cross sectional survey

    Directory of Open Access Journals (Sweden)

    Ahmed Waqas

    2015-03-01

    Full Text Available Introduction. Medicine is one of the most stressful fields of education because of its highly demanding professional and academic requirements. Psychological stress, anxiety, depression and sleep disturbances are highly prevalent in medical students.Methods. This cross-sectional study was undertaken at the Combined Military Hospital Lahore Medical College and the Institute of Dentistry in Lahore (CMH LMC, Pakistan. Students enrolled in all yearly courses for the Bachelor of Medicine and Bachelor of Surgery (MBBS degree were included. The questionnaire consisted of four sections: (1 demographics (2 a table listing 34 potential stressors, (3 the 14-item Perceived Stress Scale (PSS-14, and (4 the Pittsburgh Quality of Sleep Index (PSQI. Logistic regression was run to identify associations between group of stressors, gender, year of study, student’s background, stress and quality of sleep.Results. Total response rate was 93.9% (263/280 respondents returned the questionnaire. The mean (SD PSS-14 score was 30 (6.97. Logistic regression analysis showed that cases of high-level stress were associated with year of study and academic-related stressors only. Univariate analysis identified 157 cases with high stress levels (59.7%. The mean (SD PSQI score was 8.1 (3.12. According to PSQI score, 203/263 respondents (77% were poor sleepers. Logistic regression showed that mean PSS-14 score was a significant predictor of PSQI score (OR 1.99, P < 0.05.Conclusion. We found a very high prevalence of academic stress and poor sleep quality among medical students. Many medical students reported using sedatives more than once a week. Academic stressors contributed significantly to stress and sleep disorders in medical students.

  2. Comparing and contrasting therapeutic effects of cognitive-behavior therapy for older adults suffering from insomnia with short and long objective sleep duration.

    Science.gov (United States)

    Lovato, Nicole; Lack, Leon; Kennaway, David J

    2016-06-01

    This study evaluated the efficacy of a brief group-based program of cognitive-behavior therapy for insomnia (CBTi) for older adults suffering from chronic insomnia with short objective sleep relative to those with long sleep duration. Ninety-one adults (male = 43, mean age = 63.34, standard deviation (SD) = 6.41) with sleep maintenance insomnia were selected from a community-based sample. The participants were classified as short sleepers (SS; treatment program of CBTi (N = 30 SS; N = 33 LS) or to a wait-list control condition (N = 9 SS, N = 19 LS). One-week sleep diaries, actigraphy, and a comprehensive battery of questionnaires were used to evaluate the efficacy of CBTi for those with short objective sleep relative to those with long sleep duration. Outcome measures were taken at pretreatment, posttreatment, and a 3-month follow-up. CBTi produced robust and durable improvements in quality of sleep, including reduced wake after sleep onset and improved sleep efficiency. Participants reported a reduction of scores on the Insomnia Severity Index, Flinders Fatigue Scale, Epworth Sleepiness Scale, Daytime Feeling and Functioning Scale, Sleep Anticipatory Anxiety Questionnaire, the Dysfunctional Beliefs and Attitudes about Sleep Scale, and gains on the Sleep Self-Efficacy Scale. All improvements were significant relative to their respective SS or LS wait-list group. The benefits of CBTi were comparable with those who had short and long objective sleep before the treatment. Older adults suffering from chronic insomnia with short objective sleep received comparable therapeutic benefits following CBTi relative to those with long objective sleep duration. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. How Hyperarousal and Sleep Reactivity Are Represented in Different Adult Age Groups: Results from a Large Cohort Study on Insomnia.

    Science.gov (United States)

    Altena, Ellemarije; Chen, Ivy Y; Daviaux, Yannick; Ivers, Hans; Philip, Pierre; Morin, Charles M

    2017-04-14

    Hyperarousal is a 24-h state of elevated cognitive and physiological activation, and is a core feature of insomnia. The extent to which sleep quality is affected by stressful events-so-called sleep reactivity-is a vulnerability factor for developing insomnia. Given the increasing prevalence of insomnia with age, we aimed to investigate how hyperarousal and sleep reactivity were related to insomnia severity in different adult age groups. Data were derived from a large cohort study investigating the natural history of insomnia in a population-based sample ( n = 1693). Baseline data of the Arousal Predisposition Scale (APS) and Ford Insomnia Response to Stress Test (FIRST) were examined across age and sleep/insomnia subgroups: 25-35 ( n = 448), 35-45 ( n = 528), and 45-55 year olds ( n = 717); good sleepers ( n = 931), individuals with insomnia symptoms ( n = 450), and individuals with an insomnia syndrome ( n = 312). Results from factorial analyses of variance (ANOVA) showed that APS scores decreased with increasing age, but increased with more severe sleep problems. FIRST scores were not significantly different across age groups, but showed the same strong increase as a function of sleep problem severity. The findings indicate that though arousal predisposition and sleep reactivity increase with more severe sleep problems, only arousal decreases with age. How arousing events affect an individual during daytime thus decreases with age, but how this arousal disrupts sleep is equivalent across different adult age groups. The main implication of these findings is that treatment of insomnia could be adapted for different age groups and take into consideration vulnerability factors such as hyperarousal and stress reactivity.

  4. A Systematic Approach to Identify Sources of Abnormal Interior Noise for a High-Speed Train

    Directory of Open Access Journals (Sweden)

    Jie Zhang

    2018-01-01

    Full Text Available A systematic approach to identify sources of abnormal interior noise occurring in a high-speed train is presented and applied in this paper to resolve a particular noise issue. This approach is developed based on a number of previous dealings with similar noise problems. The particular noise issue occurs in a Chinese high-speed train. It is measured that there is a difference of 7 dB(A in overall Sound Pressure Level (SPL between two nominally identical VIP cabins at 250 km/h. The systematic approach is applied to identify the root cause of the 7 dB(A difference. Well planned measurements are performed in both the VIP cabins. Sound pressure contributions, either in terms of frequency band or in terms of facing area, are analyzed. Order analysis is also carried out. Based on these analyses, it is found that the problematic frequency is the sleeper passing frequency of the train, and an area on the roof contributes the most. In order to determine what causes that area to be the main contributor without disassembling the structure of the roof, measured noise and vibration data for different train speeds are further analyzed. It is then reasoned that roof is the main contributor caused by sound pressure behind the panel. Up to this point, panels of the roof are removed, revealing that a hole of 300 cm2 for running cables is presented behind the red area without proper sound insulation. This study can provide a basis for abnormal interior noise analysis and control of high-speed trains.

  5. Concentrations and content of mercury in bark, wood, and leaves in hardwoods and conifers in four forested sites in the northeastern USA

    Science.gov (United States)

    Yanai, Ruth D.; Driscoll, Charles T.; Montesdeoca, Mario; Smith, Kevin T.

    2018-01-01

    Mercury (Hg) is deposited from the atmosphere to remote areas such as forests, but the amount of Hg in trees is not well known. To determine the importance of Hg in trees, we analyzed foliage, bark and bole wood of eight tree species at four sites in the northeastern USA (Huntington Forest, NY; Sleepers River, VT; Hubbard Brook, NH; Bear Brook, ME). Foliar concentrations of Hg averaged 16.3 ng g-1 among the hardwood species, which was significantly lower than values in conifers, which averaged 28.6 ng g-1 (p < 0.001). Similarly, bark concentrations of Hg were lower (p < 0.001) in hardwoods (7.7 ng g-1) than conifers (22.5 ng g-1). For wood, concentrations of Hg were higher in yellow birch (2.1–2.8 ng g-1) and white pine (2.3 ng g-1) than in the other species, which averaged 1.4 ng g-1 (p < 0.0001). Sites differed significantly in Hg concentrations of foliage and bark (p = 0.02), which are directly exposed to the atmosphere, but the concentration of Hg in wood depended more on species (p < 0.001) than site (p = 0.60). The Hg contents of tree tissues in hardwood stands, estimated from modeled biomass and measured concentrations at each site, were higher in bark (mean of 0.10 g ha-1) and wood (0.16 g ha-1) than in foliage (0.06 g ha-1). In conifer stands, because foliar concentrations were higher, the foliar pool tended to be more important. Quantifying Hg in tree tissues is essential to understanding the pools and fluxes of Hg in forest ecosystems. PMID:29684081

  6. Concentrations and content of mercury in bark, wood, and leaves in hardwoods and conifers in four forested sites in the northeastern USA.

    Science.gov (United States)

    Yang, Yang; Yanai, Ruth D; Driscoll, Charles T; Montesdeoca, Mario; Smith, Kevin T

    2018-01-01

    Mercury (Hg) is deposited from the atmosphere to remote areas such as forests, but the amount of Hg in trees is not well known. To determine the importance of Hg in trees, we analyzed foliage, bark and bole wood of eight tree species at four sites in the northeastern USA (Huntington Forest, NY; Sleepers River, VT; Hubbard Brook, NH; Bear Brook, ME). Foliar concentrations of Hg averaged 16.3 ng g-1 among the hardwood species, which was significantly lower than values in conifers, which averaged 28.6 ng g-1 (p < 0.001). Similarly, bark concentrations of Hg were lower (p < 0.001) in hardwoods (7.7 ng g-1) than conifers (22.5 ng g-1). For wood, concentrations of Hg were higher in yellow birch (2.1-2.8 ng g-1) and white pine (2.3 ng g-1) than in the other species, which averaged 1.4 ng g-1 (p < 0.0001). Sites differed significantly in Hg concentrations of foliage and bark (p = 0.02), which are directly exposed to the atmosphere, but the concentration of Hg in wood depended more on species (p < 0.001) than site (p = 0.60). The Hg contents of tree tissues in hardwood stands, estimated from modeled biomass and measured concentrations at each site, were higher in bark (mean of 0.10 g ha-1) and wood (0.16 g ha-1) than in foliage (0.06 g ha-1). In conifer stands, because foliar concentrations were higher, the foliar pool tended to be more important. Quantifying Hg in tree tissues is essential to understanding the pools and fluxes of Hg in forest ecosystems.

  7. Organization of the sleep-related neural systems in the brain of the river hippopotamus (Hippopotamus amphibius): A most unusual cetartiodactyl species.

    Science.gov (United States)

    Dell, Leigh-Anne; Patzke, Nina; Spocter, Muhammad A; Bertelsen, Mads F; Siegel, Jerome M; Manger, Paul R

    2016-07-01

    This study provides the first systematic analysis of the nuclear organization of the neural systems related to sleep and wake in the basal forebrain, diencephalon, midbrain, and pons of the river hippopotamus, one of the closest extant terrestrial relatives of the cetaceans. All nuclei involved in sleep regulation and control found in other mammals, including cetaceans, were present in the river hippopotamus, with no specific nuclei being absent, but novel features of the cholinergic system, including novel nuclei, were present. This qualitative similarity relates to the cholinergic, noradrenergic, serotonergic, and orexinergic systems and is extended to the γ-aminobutyric acid (GABA)ergic elements of these nuclei. Quantitative analysis reveals that the numbers of pontine cholinergic (259,578) and noradrenergic (127,752) neurons, and hypothalamic orexinergic neurons (68,398) are markedly higher than in other large-brained mammals. These features, along with novel cholinergic nuclei in the intralaminar nuclei of the dorsal thalamus and the ventral tegmental area of the midbrain, as well as a major expansion of the hypothalamic cholinergic nuclei and a large laterodorsal tegmental nucleus of the pons that has both parvocellular and magnocellular cholinergic neurons, indicates an unusual sleep phenomenology for the hippopotamus. Our observations indicate that the hippopotamus is likely to be a bihemispheric sleeper that expresses REM sleep. The novel features of the cholinergic system suggest the presence of an undescribed sleep state in the hippopotamus, as well as the possibility that this animal could, more rapidly than other mammals, switch cortical electroencephalographic activity from one state to another. J. Comp. Neurol. 524:2036-2058, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  8. Long Sleep Duration is Associated With Sarcopenia in Korean Adults Based on Data from the 2008-2011 KNHANES.

    Science.gov (United States)

    Kwon, Yu-Jin; Jang, Suk-Yong; Park, Eun-Cheol; Cho, A-Ra; Shim, Jae-Yong; Linton, John A

    2017-09-15

    Sarcopenia, or loss of muscle mass, occurs with aging and results in frailty, disability, cardiovascular disease, and insulin resistance. Recently, researchers have asserted that sarcopenia is not an inevitable process, but is a modifiable condition. Adequate sleep duration is also important to maintain good physical and mental health. Therefore, the aim of our study was to examine the association between sleep duration and sarcopenia in Korean adults. Data from 16,148 participants (7,158 men and 8,990 women) were analyzed from the 2008-2011 Korean National Health and Nutrition Examination Survey (KNHANES). We defined sarcopenia as one standard deviation below the sex-specific means of the appendicular skeletal muscle/height-squared values of a young reference group. Participants were categorized into 5 groups according to sleep duration. The odds ratios (OR) and 95% confidence intervals (95% CI) for sarcopenia according to sleep duration were calculated using multiple logistic regression analysis. The prevalence of sarcopenia was 14.3% in the total population (males 18.7%, females 9.7%). Compared to the 7 hours of sleep group, the OR (95% CI) for sarcopenia of the long sleep duration group (9 hours or more) was 1.589 (1.100-2.295) after controlling for confounding factors. From the results of subgroup analysis, high-risk groups for sarcopenia are as follows: 40-64 years old (OR = 1.868), normal body mass index (OR = 1.516), smoking (OR = 2.219), no regular exercise (OR = 1.506) in long sleepers. Long sleep duration (9 hours or longer) is independently associated with sarcopenia in Korean adults. © 2017 American Academy of Sleep Medicine

  9. Vibro-acoustic performance of newly designed tram track structures

    Science.gov (United States)

    Haladin, Ivo; Lakušić, Stjepan; Ahac, Maja

    2017-09-01

    Rail vehicles in interaction with a railway structure induce vibrations that are propagating to surrounding structures and cause noise disturbance in the surrounding areas. Since tram tracks in urban areas often share the running surface with road vehicles one of top priorities is to achieve low maintenance and long lasting structure. Research conducted in scope of this paper gives an overview of newly designed tram track structures designated for use on Zagreb tram network and their performance in terms of noise and vibration mitigation. Research has been conducted on a 150 m long test section consisted of three tram track types: standard tram track structure commonly used on tram lines in Zagreb, optimized tram structure for better noise and vibration mitigation and a slab track with double sleepers embedded in a concrete slab, which presents an entirely new approach of tram track construction in Zagreb. Track has been instrumented with acceleration sensors, strain gauges and revision shafts for inspection. Relative deformations give an insight into track structure dynamic load distribution through the exploitation period. Further the paper describes vibro-acoustic measurements conducted at the test site. To evaluate the track performance from the vibro-acoustical standpoint, detailed analysis of track decay rate has been analysed. Opposed to measurement technique using impact hammer for track decay rate measurements, newly developed measuring technique using vehicle pass by vibrations as a source of excitation has been proposed and analysed. Paper gives overview of the method, it’s benefits compared to standard method of track decay rate measurements and method evaluation based on noise measurements of the vehicle pass by.

  10. Familial Risk for Insomnia Is Associated With Abnormal Cortisol Response to Stress.

    Science.gov (United States)

    Drake, Christopher L; Cheng, Philip; Almeida, David M; Roth, Thomas

    2017-10-01

    Abnormalities in the stress system have been implicated in insomnia. However, studies examining physiological stress regulation in insomnia have not consistently detected differences in the hypothalamic-pituitary-adrenal (HPA)-axis response to stress. One explanation may be that deficits in the stress system are associated specifically with a biological vulnerability to insomnia rather than the phenotypic expression of insomnia. To examine stress response as a function of vulnerability to insomnia, this study tested response to the Trier Social Stress Test in a sample of healthy sleepers with varying familial risks for insomnia. Thirty-five healthy individuals with and without familial risk for insomnia were recruited to complete a laboratory stressor. Participants with one or both biological parents with insomnia were categorized as positive for familial risk, whereas those without biological parents with insomnia were categorized as negative for familial risk. Participants completed the Trier Social Stress Test in the laboratory, and psychological and physiological (autonomic and HPA-axis) responses were compared. Despite self-reported increases in anxiety, those positive for familial risk exhibited a blunted cortisol response relative to those without familial risk for insomnia. Individuals with blunted cortisol also reported heightened reactivity to personal life stressors, including increased sleep disturbances, elevated cognitive intrusions, and more behavioral avoidance. Findings from this study provide initial evidence that abnormal stress regulation may be a biological predisposing factor conferred via familial risk for insomnia. This deficit may also predict negative consequences over time, including insomnia and the associated psychiatric comorbidities. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  11. Associations of quality of sleep with lifestyle factors and profile of studies among Lithuanian students.

    Science.gov (United States)

    Preišegolavičiūtė, Evelina; Leskauskas, Darius; Adomaitienė, Virginija

    2010-01-01

    The objective of the study was to analyze associations among quality of sleep, profile of the studies, and lifestyle factors among the students of three different study profiles (medicine, economics, and law). A total of 405 randomly selected students from the first and fourth years of studies from 4 different universities in Lithuania answered the standardized questionnaires consisting of two parts: 1) the Pittsburgh Sleep Quality Index (PSQI) for subjective evaluation of sleep quality; 2) the questionnaire about sleep and lifestyle habits and impact of poor sleep on the quality of life developed by the researchers. More than half (59.4%) of the students scored higher than 5 on the PSQI, which allowed suspecting sleep disorders. A significant difference in the frequency of poor sleepers was found regarding the profile of studies (Pstudents. There was a significant correlation between quality of sleep and subjective evaluation of quality of life (Pstudents experienced the highest impact of poor sleep on the quality of life (P=0.008). Students studying before going to sleep, spending more time studying, and having less leisure time had worse quality of sleep (Pstudents of medicine. The incidence of sleep problems is high among students in Lithuania, reaching 59.4%. Medical students have worse quality of sleep and worse impact of poor sleep on the quality of life compared to students of law and economics. A significant difference was found between medical students and their peers in other profiles of studies regarding their attitudes and habits related to studies: medical students spent more time for studying, were more anxious about studies and less satisfied with the results, studied more often before going to sleep.

  12. Determination of chromated copper arsenate (CCA) in treated wood of Eucalyptus

    Energy Technology Data Exchange (ETDEWEB)

    Parreira, Paulo S., E-mail: parreira@uel.b [Universidade Estadual de Londrina (UEL), PR (Brazil). Dept. de Fisica. Lab.de Fisica Nuclear Aplicada; Vendrametto, Guilherme R.; Cunha, Magda E.T., E-mail: grvendrametto@gmail.co [Universidade Norte do Parana, Arapongas, PR (Brazil). Centro de Ciencias Humanas, da Saude, Exatas e Tecnologicas-A

    2009-07-01

    This work deals with the possible application of a portable energy dispersive handmade system (PXRF-LFNA-02) for the determination of Chromium, Copper and Arsenic in the preservative solution used to protect commercial wood of Eucalyptus, which are employed as wood fence, posts, contention fences, railroad sleepers, etc. It was prepared five body-of-proof made of eucalyptus alburnum with different concentrations for each element varying from 0.0061 to 0.0180 (g/g) for CrO{sub 3}, 0.0024 to 0.0070 (g/g) for CuO and 0.0044 to 0.0129 (g/g) for As{sub 2}O{sub 5}. Four of them were used for calibration curves and one used as reference sample. It was used a commercial CCA (Chromated Copper Arsenate ) solution to prepare the samples. The results show a good linear regression between concentrations and X-rays intensities, after applied the multiple linear regression methodology for interelemental corrections. The values obtained with this methodology were 3.01(kg/m{sup 3}), 1.18 (kg/m{sup 3}) e 2.21 (kg/m{sup 3}) for CrO{sub 3}, CuO and As{sub 2}O{sub 5}, respectively, while the nominal values are 2.90 (kg/m{sup 3}) for CrO{sub 3}, 1.13 (kg/m{sup 3}) for CuO and 2.07 (kg/m{sup 3}) for As{sub 2}O{sub 5}. The ED-XRF (Energy Dispersive X-Rays Fluorescence) is a well established technique with high-speed of analytical procedure and its portable configuration allowing a multielemental, simultaneous and non destructive analyses besides in situ application. (author)

  13. Sleep disturbance in psoriasis - a case-controlled study.

    Science.gov (United States)

    Jensen, P; Zachariae, C; Skov, L; Zachariae, R

    2018-04-28

    Sleep is essential for daytime functioning and health. Given the physical symptoms of psoriasis, a higher prevalence of sleep disorders could be expected. So far, the studies examining sleep disturbance in psoriasis have been of less-than-optimal methodological quality and with mixed results. We aimed to: 1) examine the prevalence of sleep disturbance in patients with plaque psoriasis compared to controls, 2) evaluate associations with health-related quality of life (HRQoL), and 3) examine possible disease-related predictors of disturbed sleep. We used a cross-sectional, case-controlled design. Participants included 179 consecutively recruited patients with plaque psoriasis and 105 controls. Measures included psoriasis severity (Psoriasis Area and Severity index [PASI]); HRQoL (Dermatology Life Quality Index [DLQI]); insomnia severity (Insomnia Severity Index [ISI]); sleep quality (Pittsburgh Sleep Quality Index [PSQI]); stress (Perceived Stress Scale [PSS]); Itch (Itch Severity Scale [ISS]); and depressive symptoms (Beck Depression Inventory [BDI]). Analyses included group comparisons and regression analyses to identify predictors of sleep disturbance. Twenty-five per cent of patients with psoriasis reported clinical insomnia (ISI > 15), compared with 10.5% of controls. In all, 53.9% of patients with psoriasis were poor sleepers (PSQI > 5), compared with 21.9% of controls. Itch was statistically significantly associated with all sleep-related outcomes. A higher proportion of patients with psoriasis suffer from poor sleep than controls from the general population. Itch was the main predictor of impaired sleep. Improved control of psoriasis with decreased itch may improve sleep disturbance in psoriasis. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  14. Illness narratives of people who are homeless

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    Cecilia Håkanson

    2016-11-01

    Full Text Available Multiple illnesses are common in all homeless populations. While most previous studies have focused on experiences of mental illness, there is a scarcity of studies about experiences of bodily illness among people who are homeless. This study aimed to explore illness narratives of people who are homeless, and how homelessness as a social context shapes the experience of multiple and/or advancing somatic conditions. The design was a qualitative single-case study, using interpretive description. Data were generated through interviews, with nine participants who were homeless rough sleepers in Stockholm, Sweden, recruited while receiving care in a support home for homeless people with complex care needs. The findings revealed experiences of illness embedded in narratives about falling ill, being ill, and the future. The particularity of these illness narratives and the way that they are shaped by homelessness give rise to several observations: the necessity of a capable body for survival; chaos and profound solitude in illness and self-care management; ambiguous feelings about receiving care, transitioning from independence, and “freedom” in the streets to dependency and being institutionalized; and finally, the absence of hope and desire for recovery or a better future. The narratives are discussed from the perspective of Frank's four types of illness stories (restitution, chaos, quest, and testimony. The findings stress that to provide appropriate care and support to people who are homeless and have multiple and/or advancing somatic conditions, health care professionals need to be informed both about the individual's biography and about the circumstances under which illness and self-care takes place in the streets.

  15. Sleep characteristics as predictor variables of stress systems markers in insomnia disorder.

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    Floam, Samantha; Simpson, Norah; Nemeth, Emese; Scott-Sutherland, Jennifer; Gautam, Shiva; Haack, Monika

    2015-06-01

    This study investigates the extent to which sleep characteristics serve as predictor variables for inflammatory, hypothalamic-pituitary-adrenal and autonomic systems markers. Twenty-nine participants with a diagnosis of insomnia disorder based on the Diagnostic Statistical Manual of Mental Disorders, Fifth Edition (age 25.3 ± 1.6 years, insomnia duration 6.6 ± 0.8 years) and 19 healthy control sleepers (age 25.4 ± 1.4 years) underwent a 2-week at-home evaluation keeping a sleep diary and wearing an actigraph, followed by a visit to the Research Center to measure blood pressure, and collect blood and urine samples. The actigraphy- and diary-based variables of sleep duration, sleep-onset latency, wake after sleep onset and sleep fragmentation/number of night-time awakenings were averaged and entered as dependent variables in regression analyses. Composite scores were calculated for the autonomic (blood pressure, norepinephrine), inflammatory (monocyte counts, interleukin-6, C-reactive protein) and hypothalamic-pituitary-adrenal systems (cortisol), and used as predictor variables in regression models. Compared with controls, individuals with insomnia had a shorter sleep duration (P insomnia disorder, cortisol is upregulated and associated with actigraphy- and diary-based wake after sleep onset, suggesting that wake after sleep onset may serve as a marker to identify individuals at increased risks for disorders associated with a hyperactive hypothalamic-pituitary-adrenal system. The absence of autonomic and pro-inflammatory changes (interleukin-6, C-reactive protein), despite a substantial decrease in actigraphic sleep duration, may relate to a higher resilience to the adverse biological consequences of insomnia in this young age group. © 2014 European Sleep Research Society.

  16. The bedding environment, sleep position, and frequent wheeze in childhood.

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    Ponsonby, Anne-Louise; Dwyer, Terence; Trevillian, Leigh; Kemp, Andrew; Cochrane, Jennifer; Couper, David; Carmichael, Allan

    2004-05-01

    Synthetic quilt use has been associated with increased childhood wheeze in previous studies. Our aim was to examine whether the adverse effect of synthetic quilt use on frequent wheeze differed by usual sleep position. A population-based cross-sectional study of 6378 (92% of those eligible) 7-year-olds in Tasmania, Australia, was conducted in 1995. Exercise-challenge lung function was obtained on a subset of 414 children from randomly selected schools. Child bedding including pillow and overbedding composition and usual sleep position by parental questionnaire. Frequent wheeze (>12 wheeze episodes over the past year), using the International Study of Asthma and Allergies in Childhood parental questionnaire, and baseline and postexercise forced expiratory volume in 1 second lung-function measures. Frequent wheeze (n = 117) was positively associated with synthetic quilts, synthetic pillows, electric blankets, and sleeping in a bottom bunk bed but did not vary by sleep position. In a nested case-control analysis, the association between synthetic quilt use and frequent wheeze differed by sleep position. Among children who slept supine, synthetic (versus feather) quilt use was associated with frequent wheeze (adjusted odds ratio: 2.37 [1.08, 5.23]). However, among nonsupine sleepers, overlying synthetic quilt use was not associated with frequent wheeze (adjusted odds ratio: 1.06 [0.60, 1.88]). This difference in quilt effect by sleep position was highly significant. Similarly, synthetic quilt use was associated with lower postexercise forced expiratory volume in 1 second measures among supine but not nonsupine sleeping children. An increasing focus on the bedding environment immediately adjacent to the nose and mouth is required for respiratory disorders provoked by bedding, such as child asthma characterized by frequent wheeze.

  17. Sleep Quality and its Associated Factors in Iranian Patients with Breast Cancer

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    Farzaneh Habibi

    2016-12-01

    Full Text Available Background: Sleep disturbances are common, but widely underdiagnosed in cancer patients. Thus, the aim of the present study was to evaluate sleep quality and its associated factors among women with breast cancer.Methods: This cross-sectional study was conducted on women with breast cancer referring to 2 outpatient clinics in Isfahan, Iran. Sleep quality [Pittsburgh Sleep Quality Index (PSQI], severity of anxiety and depression [Hospital Anxiety and Depression Scale (HADS], cancer symptoms [M.D. Anderson Symptom Inventory (MDASI‎], and quality of life (QOL [European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-‎Core 30 (EORTC QLQ-C30] were assessed in the present study.Results: The study population consisted of 101 patients with mean age of 49.7 years and mean cancer duration of 2.3 years. The mean global PSQI score of patients was 8.5 and 80.2% had poor sleep quality. Factors associated with global PSQI score in univariate analyses were body mass index (BMI (r = 0.445, severity of cancer symptoms (r = 0.580, anxiety (r = 0.363, and depression (r = 0.332. BMI and symptom severity were independently associated with poor sleep quality (standardized coefficient = 0.388 and 0.480, respectively. With regards to QOL, patients with poor sleep quality had lower physical and psychosocial functioning than good sleepers.Conclusion: Sleep disturbances are highly common in women with breast cancer in our society and significantly affect their QOL. Obesity, cancer symptoms, and psychological symptoms are important factors associated with and contributing to sleep problems in these patients. Cancer care programs must have a comprehensive approach, including sleep assessment and management, toward the treatment of these patients.

  18. Sleep location and parent-perceived sleep outcomes in older infants.

    Science.gov (United States)

    Mindell, Jodi A; Leichman, Erin S; Walters, Russel M

    2017-11-01

    Initial studies indicate more independent and consolidated sleep in the first few months in infants who sleep separately. Little is known, however, about the relationship of sleep location (separate room, room-sharing, bed-sharing) with sleep outcomes in older infants (ages 6-12 months). It was expected that those who sleep in a separate room would have better parent-perceived sleep outcomes and more positive sleep health behaviors. Parents of 6236 infants (6-12 months) in the United States (US) and 3798 in an international sample (Australia, Brazil, Canada, Great Britain, and New Zealand) completed a smartphone app-based expanded version of the validated Brief Infant Sleep Questionnaire. A total of 37.2% of the infants in the US and 48.4% in the international sample slept in a separate room. In both samples, infants who slept in a separate room as opposed to room-sharing or bed-sharing had parent-perceived sleep outcomes and sleep-related behaviors that reflected earlier bedtimes, shorter time to fall asleep, more nighttime and total sleep, and increased sleep consolidation. They were also more likely to have a consistent bedtime routine and to fall asleep independently, as well as less likely to feed to sleep at bedtime and during the night. In addition, parents of separate room sleepers perceived bedtime to be less difficult and sleep to be better overall. Overall, 6- to 12-month-old infants who slept in a separate room had better reported sleep outcomes and fewer parent-perceived disturbances at bedtime than infants who room-shared with their parents, as well compared to those who slept in their parents' bed. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Topological Reorganization of the Default Mode Network in Severe Male Obstructive Sleep Apnea

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    Liting Chen

    2018-06-01

    Full Text Available Impaired spontaneous regional activity and altered topology of the brain network have been observed in obstructive sleep apnea (OSA. However, the mechanisms of disrupted functional connectivity (FC and topological reorganization of the default mode network (DMN in patients with OSA remain largely unknown. We explored whether the FC is altered within the DMN and examined topological changes occur in the DMN in patients with OSA using a graph theory analysis of resting-state functional magnetic resonance imaging data and evaluated the relationship between neuroimaging measures and clinical variables. Resting-state data were obtained from 46 male patients with untreated severe OSA and 46 male good sleepers (GSs. We specifically selected 20 DMN subregions to construct the DMN architecture. The disrupted FC and topological properties of the DMN in patients with OSA were characterized using graph theory. The OSA group showed significantly decreased FC of the anterior–posterior DMN and within the posterior DMN, and also showed increased FC within the DMN. The DMN exhibited small-world topology in both OSA and GS groups. Compared to GSs, patients with OSA showed a decreased clustering coefficient (Cp and local efficiency, and decreased nodal centralities in the left posterior cingulate cortex and dorsal medial prefrontal cortex, and increased nodal centralities in the ventral medial prefrontal cortex and the right parahippocampal cortex. Finally, the abnormal DMN FC was significantly related to Cp, path length, global efficiency, and Montreal cognitive assessment score. OSA showed disrupted FC within the DMN, which may have contributed to the observed topological reorganization. These findings may provide further evidence of cognitive deficits in patients with OSA.

  20. Evaluation of the wood CCA preservative treatment process of Eucalyptus (Eucaliptus ssp) by X-ray fluorescence technique

    Energy Technology Data Exchange (ETDEWEB)

    Pereira Junior, Sergio Matias, E-mail: matias@ipt.br [Instituto de Pesquisas Tecnologicas (IPT), Sao Paulo, SP (Brazil); Salvador, Vera Lucia Ribeiro; Sato, Ivone Mulako, E-mail: imsato@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    Brazil produces around 1,2 mi m{sup 3} of treated wood to meet the annual demand of railway, electric, rural and construction sectors. The treated woods used for poles, sleepers, fence posts and plywoods should be according to Brazilian norms requirements. The most used wood species are eucalyptus (Eucaliptus ssp)and pine (Pinus ssp). The most wood preservative products used in Brazil are CCA (Chromated Copper Arsenate) and CCB (Copper Chromium and Boron Salt). The analytical methods, such as Flame Atomic Absorption Spectrometry (FAAS) and Plasma Inductively Coupled Optical Emission Spectrometry (ICPOES) have been used for the evaluation of those treatment processes. In this work, the sapwood sample was obtained from eucalyptus trees (Eucaliptus ssp) obtained from Minas Gerais State, Brazil, cut plantation areas. Sawdust sapwood sample was grounded and submitted to different additions of CCA solutions (0.2, 0.7, 1.3, 2.3, 3.6, 6.3, 11.7and17.9 kg m{sup -3}). Power and pressed pellets sapwood samples, analyzed by EDXRFS, showed a good linear relation (r{sup 2}>0.99) between the characteristic intensity fluorescent lines (CuΚα, CrΚαand AsΚΒ) and their concentration, also, showed adequate sensitivity (LQ < 5mgkg{sup -1}) for Cu, Cr and As determination in treated woods. Cu, Cr and As were determined in powdered sawdust samples by FAA spectrometry, using the AWPA A11-93 standard method; the relation between the CCA retention and their concentration showed a lower linear relation than EDXRFS; the FAAS spreading result could be attributed to laboratorial CCA addition process. (author)

  1. Relationship of slow and rapid EEG components of CAP to ASDA arousals in normal sleep.

    Science.gov (United States)

    Parrino, L; Smerieri, A; Rossi, M; Terzano, M G

    2001-12-15

    Besides arousals (according to the ASDA definition), sleep contains also K-complexes and delta bursts which, in spite of their sleep-like features, are endowed with activating effects on autonomic functions. The link between phasic delta activities and enhancement of vegetative functions indicates the possibility of physiological activation without sleep disruption (i.e., arousal without awakening). A functional connection seems to include slow (K-complexes and delta bursts) and rapid (arousals) EEG events within the comprehensive term of activating complexes. CAP (cyclic alternating pattern) is the spontaneous EEG rhythm that ties both slow and rapid activating complexes together during NREM sleep. The present study aims at exploring the relationship between arousals and CAP components in a selected sample of healthy sleepers. Polysomnographic analysis according to the scoring rules for sleep stages and arousals. CAP analysis included also tabulation of subtypes A1 (slow EEG activating complexes), A2 and A3 (activating complexes with fast EEG components). 40 sleep-lab accomplished recordings. Healthy subjects belonging to a wide age range (38 +/- 20 yrs.). N/A. Of all the arousals occurring in NREM sleep, 87% were inserted within CAP. Subtypes A2 and A3 of CAP corresponded strikingly with arousals (r=0.843; p<0.0001), while no statistical relationship emerged when arousals were matched with subtypes A1 of CAP. Subtypes A1 instead correlated positively with the percentages of deep sleep (r=0.366; p<0.02). The CAP subtype classification encompasses both the process of sleep maintenance (subtypes A1) and sleep fragmentation (subtypes A2 and A3), and provides a periodicity dimension to the activating events of NREM sleep.

  2. Rest but busy: Aberrant resting-state functional connectivity of triple network model in insomnia.

    Science.gov (United States)

    Dong, Xiaojuan; Qin, Haixia; Wu, Taoyu; Hu, Hua; Liao, Keren; Cheng, Fei; Gao, Dong; Lei, Xu

    2018-02-01

    One classical hypothesis among many models to explain the etiology and maintenance of insomnia disorder (ID) is hyperarousal. Aberrant functional connectivity among resting-state large-scale brain networks may be the underlying neurological mechanisms of this hypothesis. The aim of current study was to investigate the functional network connectivity (FNC) among large-scale brain networks in patients with insomnia disorder (ID) during resting state. In the present study, the resting-state fMRI was used to evaluate whether patients with ID showed aberrant FNC among dorsal attention network (DAN), frontoparietal control network (FPC), anterior default mode network (aDMN), and posterior default mode network (pDMN) compared with healthy good sleepers (HGSs). The Pearson's correlation analysis was employed to explore whether the abnormal FNC observed in patients with ID was associated with sleep parameters, cognitive and emotional scores, and behavioral performance assessed by questionnaires and tasks. Patients with ID had worse subjective thought control ability measured by Thought Control Ability Questionnaire (TCAQ) and more negative affect than HGSs. Intriguingly, relative to HGSs, patients with ID showed a significant increase in FNC between DAN and FPC, but a significant decrease in FNC between aDMN and pDMN. Exploratory analysis in patients with ID revealed a significantly positive correlation between the DAN-FPC FNC and reaction time (RT) of psychomotor vigilance task (PVT). The current study demonstrated that even during the resting state, the task-activated and task-deactivated large-scale brain networks in insomniacs may still maintain a hyperarousal state, looking quite similar to the pattern in a task condition with external stimuli. Those results support the hyperarousal model of insomnia.

  3. Sleep Quality and Academic Progression among Students of Tabriz University of Medical Sciences, Northwest of Iran

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    Horyeh Sarbazvatan

    2017-06-01

    Full Text Available Background: Sleep deprivation and drowsiness are very common among university students. The aim of this study was to examine the sleep quality and academic achievement among university students across all medical disciplines in Northwest of Iran. Methods: This study was based on data from a longitudinal study, the "Health and Lifestyle of University Students" (HeLiS. The Pittsburgh Sleep Quality Index (PSQI, a self-administered questionnaire consisting of general information about sleep quality, was completed by students during the first eight weeks of the first semester and academic achievement was assessed via Grade Point Average (GPA in the two semesters following the administration of the PSQI. Results: The mean age of students was 19.16±1.04 and the majority were female (64%. The mean overall score on the PSQI was 6.87±2.25; the majority of students (70% had a global PSQI score greater than 5, indicating they were poor sleepers. Only 28% reported getting over 7 hours of sleep. Female students had higher scores than male students in subjective sleep quality, which was statistically significant (2.15 vs. 1.95 respectively, P = 0.01; however, there was no difference between males and females on other component scores or on the global score. Results of a multiple regression model showed that PSQI score was a predictor of academic achievement (β=-.07, P=0.035, which implies that GPA will be lower among students whose quality of sleep is lower. Conclusion: Based on our sleep quality should be considered and assessed, and sleep hygiene should be promoted among medical university students in order to improve academic achievement.

  4. Coral colonisation of an artificial reef in a turbid nearshore environment, Dampier Harbour, western Australia.

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    David Blakeway

    Full Text Available A 0.6 hectare artificial reef of local rock and recycled concrete sleepers was constructed in December 2006 at Parker Point in the industrial port of Dampier, western Australia, with the aim of providing an environmental offset for a nearshore coral community lost to land reclamation. Corals successfully colonised the artificial reef, despite the relatively harsh environmental conditions at the site (annual water temperature range 18-32°C, intermittent high turbidity, frequent cyclones, frequent nearby ship movements. Coral settlement to the artificial reef was examined by terracotta tile deployments, and later stages of coral community development were examined by in-situ visual surveys within fixed 25 x 25 cm quadrats on the rock and concrete substrates. Mean coral density on the tiles varied from 113 ± 17 SE to 909 ± 85 SE per m(2 over five deployments, whereas mean coral density in the quadrats was only 6.0 ± 1.0 SE per m(2 at eight months post construction, increasing to 24.0 ± 2.1 SE per m(2 at 62 months post construction. Coral taxa colonising the artificial reef were a subset of those on the surrounding natural reef, but occurred in different proportions--Pseudosiderastrea tayami, Mycedium elephantotus and Leptastrea purpurea being disproportionately abundant on the artificial reef. Coral cover increased rapidly in the later stages of the study, reaching 2.3 ± 0.7 SE % at 62 months post construction. This study indicates that simple materials of opportunity can provide a suitable substrate for coral recruitment in Dampier Harbour, and that natural colonisation at the study site remains sufficient to initiate a coral community on artificial substrate despite ongoing natural and anthropogenic perturbations.

  5. Regular Practice of Competitive Sports Does Not Impair Sleep in Adolescents: DADOS Study.

    Science.gov (United States)

    Beltran-Valls, María Reyes; García Artero, Enrique; Capdevila-Seder, Ana; Legaz-Arrese, Alejandro; Adelantado-Renau, Mireia; Moliner-Urdiales, Diego

    2018-05-01

    To analyze differences in sleep quality and duration by athletic status and sex, and to examine the association between physical activity (PA) recommendation and sleep in adolescents. A total of 267 adolescents [13.9 (0.3) y] from Deporte, ADOlescencia y Salud (DADOS) study (129 girls) were included in this cross-sectional analysis. Athletes competed regularly in organized sport events and trained ≥3 days per week, but nonathletes did not compete. PA was assessed by GENEActiv accelerometer. PA values were dichotomized into inactive (Sleep quality was evaluated with the Spanish version of the Pittsburgh Sleep Quality Index. Pittsburgh Sleep Quality Index values were dichotomized into >5 (poor quality) or ≤5 (good quality). Sleep duration was objectively measured by accelerometer. Sleep quality and duration were not statistically different between athletes [median (Mdn) = 4.0, interquartile range (IQR) = 3.0-6.0 and Mdn = 8.0, IQR = 7.4-8.6 h, respectively] and nonathletes (Mdn = 5.0, IQR = 3.0-7.0 and Mdn = 7.9; IQR = 7.3-8.6 h, respectively), P > .05. Nonathlete or inactive adolescents did not show higher risk for poor sleep quality or short sleep duration than athletes [odds ratio (OR) = 1.17; 95% confidence interval (CI), 0.68-2.00 and OR = 0.93; 95% CI, 0.56-1.55, respectively] or active peers (OR = 1.39; 95% CI, 0.66-2.89 and OR = 1.62; 95% CI, 0.78-3.37, respectively). In our group of adolescents, competitive sport practice did not alter sleep patterns. PA recommendations for adolescents may not discriminate between good and poor sleepers.

  6. Experimental hut evaluation of bednets treated with an organophosphate (chlorpyrifos-methyl or a pyrethroid (lambdacyhalothrin alone and in combination against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes

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    Corbel Vincent

    2005-05-01

    Full Text Available Abstract Background Pyrethroid resistant mosquitoes are becoming increasingly common in parts of Africa. It is important to identify alternative insecticides which, if necessary, could be used to replace or supplement the pyrethroids for use on treated nets. Certain compounds of an earlier generation of insecticides, the organophosphates may have potential as net treatments. Methods Comparative studies of chlorpyrifos-methyl (CM, an organophosphate with low mammalian toxicity, and lambdacyhalothrin (L, a pyrethroid, were conducted in experimental huts in Côte d'Ivoire, West Africa. Anopheles gambiae and Culex quinquefasciatus mosquitoes from the area are resistant to pyrethroids and organophosphates (kdr and insensitive acetylcholinesterase Ace.1R. Several treatments and application rates on intact or holed nets were evaluated, including single treatments, mixtures, and differential wall/ceiling treatments. Results and Conclusion All of the treatments were effective in reducing blood feeding from sleepers under the nets and in killing both species of mosquito, despite the presence of the kdr and Ace.1R genes at high frequency. In most cases, the effects of the various treatments did not differ significantly. Five washes of the nets in soap solution did not reduce the impact of the insecticides on A. gambiae mortality, but did lead to an increase in blood feeding. The three combinations performed no differently from the single insecticide treatments, but the low dose mixture performed encouragingly well indicating that such combinations might be used for controlling insecticide resistant mosquitoes. Mortality of mosquitoes that carried both Ace.1R and Ace.1S genes did not differ significantly from mosquitoes that carried only Ace.1S genes on any of the treated nets, indicating that the Ace.1R allele does not confer effective resistance to chlorpyrifos-methyl under the realistic conditions of an experimental hut.

  7. Aberrant brain functional connectome in patients with obstructive sleep apnea.

    Science.gov (United States)

    Chen, Li-Ting; Fan, Xiao-Le; Li, Hai-Jun; Ye, Cheng-Long; Yu, Hong-Hui; Xin, Hui-Zhen; Gong, Hong-Han; Peng, De-Chang; Yan, Li-Ping

    2018-01-01

    Obstructive sleep apnea (OSA) is accompanied by widespread abnormal spontaneous regional activity related to cognitive deficits. However, little is known about the topological properties of the functional brain connectome of patients with OSA. This study aimed to use the graph theory approaches to investigate the topological properties and functional connectivity (FC) of the functional connectome in patients with OSA, based on resting-state functional magnetic resonance imaging (rs-fMRI). Forty-five male patients with newly diagnosed untreated severe OSA and 45 male good sleepers (GSs) underwent a polysomnography (PSG), clinical evaluations, and rs-fMRI scans. The automated anatomical labeling (AAL) atlas was used to construct the functional brain connectome. The topological organization and FC of brain functional networks in patients with OSA were characterized using graph theory methods and investigated the relationship between functional network topology and clinical variables. Both the patients with OSA and the GSs exhibited high-efficiency "small-world" network attributes. However, the patients with OSA exhibited decreased σ, γ, E glob ; increased Lp, λ; and abnormal nodal centralities in several default-mode network (DMN), salience network (SN), and central executive network (CEN) regions. However, the patients with OSA exhibited abnormal functional connections between the DMN, SN, and CEN. The disrupted FC was significantly positive correlations with the global network metrics γ and σ. The global network metrics were significantly correlated with the Epworth Sleepiness Scale (ESS) score, Montreal Cognitive Assessment (MoCA) score, and oxygen desaturation index. The findings suggest that the functional connectome of patients with OSA exhibited disrupted functional integration and segregation, and functional disconnections of the DMN, SN, and CEN. The aberrant topological attributes may be associated with disrupted FC and cognitive functions. These

  8. Sleep extension normalizes ERP of waking auditory sensory gating in healthy habitually short sleeping individuals.

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    Gumenyuk, Valentina; Korzyukov, Oleg; Roth, Thomas; Bowyer, Susan M; Drake, Christopher L

    2013-01-01

    Chronic sleep loss has been associated with increased daytime sleepiness, as well as impairments in memory and attentional processes. In the present study, we evaluated the neuronal changes of a pre-attentive process of wake auditory sensory gating, measured by brain event-related potential (ERP)--P50 in eight normal sleepers (NS) (habitual total sleep time (TST) 7 h 32 m) vs. eight chronic short sleeping individuals (SS) (habitual TST ≤6 h). To evaluate the effect of sleep extension on sensory gating, the extended sleep condition was performed in chronic short sleeping individuals. Thus, one week of time in bed (6 h 11 m) corresponding to habitual short sleep (hSS), and one week of extended time (∼ 8 h 25 m) in bed corresponding to extended sleep (eSS), were counterbalanced in the SS group. The gating ERP assessment was performed on the last day after each sleep condition week (normal sleep and habitual short and extended sleep), and was separated by one week with habitual total sleep time and monitored by a sleep diary. We found that amplitude of gating was lower in SS group compared to that in NS group (0.3 µV vs. 1.2 µV, at Cz electrode respectively). The results of the group × laterality interaction showed that the reduction of gating amplitude in the SS group was due to lower amplitude over the left hemisphere and central-midline sites relative to that in the NS group. After sleep extension the amplitude of gating increased in chronic short sleeping individuals relative to their habitual short sleep condition. The sleep condition × frontality interaction analysis confirmed that sleep extension significantly increased the amplitude of gating over frontal and central brain areas compared to parietal brain areas.

  9. Sleep extension normalizes ERP of waking auditory sensory gating in healthy habitually short sleeping individuals.

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    Valentina Gumenyuk

    Full Text Available Chronic sleep loss has been associated with increased daytime sleepiness, as well as impairments in memory and attentional processes. In the present study, we evaluated the neuronal changes of a pre-attentive process of wake auditory sensory gating, measured by brain event-related potential (ERP--P50 in eight normal sleepers (NS (habitual total sleep time (TST 7 h 32 m vs. eight chronic short sleeping individuals (SS (habitual TST ≤6 h. To evaluate the effect of sleep extension on sensory gating, the extended sleep condition was performed in chronic short sleeping individuals. Thus, one week of time in bed (6 h 11 m corresponding to habitual short sleep (hSS, and one week of extended time (∼ 8 h 25 m in bed corresponding to extended sleep (eSS, were counterbalanced in the SS group. The gating ERP assessment was performed on the last day after each sleep condition week (normal sleep and habitual short and extended sleep, and was separated by one week with habitual total sleep time and monitored by a sleep diary. We found that amplitude of gating was lower in SS group compared to that in NS group (0.3 µV vs. 1.2 µV, at Cz electrode respectively. The results of the group × laterality interaction showed that the reduction of gating amplitude in the SS group was due to lower amplitude over the left hemisphere and central-midline sites relative to that in the NS group. After sleep extension the amplitude of gating increased in chronic short sleeping individuals relative to their habitual short sleep condition. The sleep condition × frontality interaction analysis confirmed that sleep extension significantly increased the amplitude of gating over frontal and central brain areas compared to parietal brain areas.

  10. Associated Factors of Sleep Quality and Behavior among Students of Two Tertiary Institutions in Northern Malaysia.

    Science.gov (United States)

    Lai, P P; Say, Y H

    2013-06-01

    The objective of the study was to investigate the associated factors of sleep quality and behavior among Malaysian tertiary students. The response rate to the questionnaire study was 41.0%. 1,118 students (M = 486, F = 632; mean age = 20.06 ± 1.53 years) were recruited from Universiti and Kolej Tunku Abdul Rahman (Perak campuses) who completed a sleep quality and behavior questionnaire based on Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Horne-Ostberg Morningness-Eveningness Scale (MES) and craving of high-calorie foods. Results showed that students had the following sleeping habits - bed time = 2.41 a.m. ± 3.35 hr, rise time = 9.00 a.m. ± 1.76 hr, sleep latency = 16.65 ± 14.30 min and sleep duration = 7.31 ± 1.45 hr. 32.9% of the students were defined as poor quality sleepers, 30.6% suffering excessive daytime sleepiness (EDS) and 81.6% were categorized as individuals with 'definitely eveningness', defined as people who are definitely most alert in the late evening hours and prefer to go to bed late. There were no significant gender differences in sleep quality, 'chronotype' and EDS. Although there was no association of sleep quality and EDS with cumulative Grade Point Average (cGPA) and class skipping, EDS was associated with the tendency to fall asleep in class. Body Mass Index (BMI) was not associated with total sleep, PSQI, ESS and MES scores. Meanwhile, high-calorie food craving was associated with sleep duration, PSQI and ESS, but not MES. In conclusion, poor sleep behavior among Malaysian tertiary students in this study was not associated with gender, academic performance and BMI, but was associated with craving of high-calorie foods instead.

  11. Abnormal Intrinsic Functional Hubs in Severe Male Obstructive Sleep Apnea: Evidence from a Voxel-Wise Degree Centrality Analysis.

    Science.gov (United States)

    Li, Haijun; Li, Lan; Shao, Yi; Gong, Honghan; Zhang, Wei; Zeng, Xianjun; Ye, Chenglong; Nie, Si; Chen, Liting; Peng, Dechang

    2016-01-01

    Obstructive sleep apnea (OSA) has been associated with changes in brain structure and regional function in certain brain areas. However, the functional features of network organization in the whole brain remain largely uncertain. The purpose of this study was to identify the OSA-related spatial centrality distribution of the whole brain functional network and to investigate the potential altered intrinsic functional hubs. Forty male patients with newly confirmed severe OSA on polysomnography, and well-matched good sleepers, participated in this study. All participants underwent a resting-state functional MRI scan and clinical and cognitive evaluation. Voxel-wise degree centrality (DC) was measured across the whole brain, and group difference in DC was compared. The relationship between the abnormal DC value and clinical variables was assessed using a linear correlation analysis. Remarkably similar spatial distributions of the functional hubs (high DC) were found in both groups. However, OSA patients exhibited a pattern of significantly reduced regional DC in the left middle occipital gyrus, posterior cingulate cortex, left superior frontal gyrus, and bilateral inferior parietal lobule, and DC was increased in the right orbital frontal cortex, bilateral cerebellum posterior lobes, and bilateral lentiform nucleus, including the putamen, extending to the hippocampus, and the inferior temporal gyrus, which overlapped with the functional hubs. Furthermore, a linear correlation analysis revealed that the DC value in the posterior cingulate cortex and left superior frontal gyrus were positively correlated with Montreal cognitive assessment scores, The DC value in the left middle occipital gyrus and bilateral inferior parietal lobule were negatively correlated with apnea-hypopnea index and arousal index in OSA patients. Our findings suggest that OSA patients exhibited specific abnormal intrinsic functional hubs including relatively reduced and increased DC. This expands

  12. Crew Factors in Flight Operations XII: A Survey of Sleep Quantity and Quality in On-Board Crew Rest Facilities

    Science.gov (United States)

    Rosekind, Mark R.; Gregory, Kevin B.; Co, Elizabeth L.; Miller, Donna L.; Dinges, David F.

    2000-01-01

    Many aircraft operated on long-haul commercial airline flights are equipped with on-board crew rest facilities, or bunks, to allow crewmembers to rest during the flight. The primary objectives of this study were to gather data on how the bunks were used, the quantity and quality of sleep obtained by flight crewmembers in the facilities, and the factors that affected their sleep. A retrospective survey comprising 54 questions of varied format addressed demographics, home sleep habits, and bunk sleep habits. Crewmembers from three airlines with long-haul fleets carrying augmented crews consisting of B747-100/200, B747-400, and MD-11 aircraft equipped with bunks returned a total of 1404 completed surveys (a 37% response rate). Crewmembers from the three carriers were comparable demographically, although one carrier had older, more experienced flight crewmembers. Each group, on average, rated themselves as "good" or "very good" sleepers at home, and all groups obtained about the same average amount of sleep each night. Most were able to sleep in the bunks, and about two thirds indicated that these rest opportunities benefited their subsequent flight deck alertness and performance. Comfort, environment, and physiology (e.g., being ready for sleep) were identified as factors that most promoted sleep. Factors cited as interfering with sleep included random noise, thoughts, heat, and the need to use the bathroom. These factors, in turn, suggest potential improvements to bunk facilities and their use. Ratings of the three aircraft types suggested differences among facilities. Bunks in the MD-11 were rated significantly better than either of the B747 types, and the B747-400 bunks received better ratings than did the older, B747-100/200 facilities.

  13. Cross-Regional Assessment Of Coupling And Variability In Precipitation-Runoff Relationships

    Science.gov (United States)

    Carey, S. K.; Tetzlaff, D.; Soulsby, C.; Buttle, J. M.; Laudon, H.; McDonnell, J. J.; McGuire, K. J.; Seibert, J.; Shanley, J. B.

    2011-12-01

    The higher mid-latitudes of the northern hemisphere are particularly sensitive to change due to the important role the zero-degree isotherm plays in the phase of precipitation and intermediate storage as snow. An international inter-catchment comparison program North-Watch seeks to improve our understanding of the sensitivity of northern catchments to change by examining their hydrological and biogeochemical variability and response. The catchments are located in Sweden (Krycklan), Scotland (Mharcaidh, Girnock and Strontian), the United States (Sleepers River, Hubbard Brook and HJ Andrews) and Canada (Catamaran, Dorset and Wolf Creek). For this study, 8 catchments with 10 continuous years of daily precipitation and runoff data were selected to assess the seasonal coupling of rainfall and runoff and the memory effect of runoff events on the hydrograph at different time scales. To assess the coupling and synchroneity of precipitation, continuous wavelet transforms and wavelet coherence were used. Wavelet spectra identified the relative importance of both annual versus seasonal flows while wavelet coherence was applied to identify over different time scales along the 10-year window how well precipitation and runoff were coupled. For example, while on a given day, precipitation may be closely coupled to runoff, a wet year may not necessarily be a high runoff year in catchments with large storage. Assessing different averaging periods in the variation of daily flows highlights the importance of seasonality in runoff response and the relative influence of rain versus snowmelt on flow magnitude and variability. Wet catchments with limited seasonal precipitation variability (Strontian, Girnock) have precipitation signals more closely coupled with runoff, whereas dryer catchments dominated by snow (Wolf Creek, Krycklan) have strongly coupling only during freshet. Most catchments with highly seasonal precipitation show strong intermittent coupling during their wet season. At

  14. Prevalence of nocturnal enuresis and related risk factors in school-age children in Egypt: an epidemiological study.

    Science.gov (United States)

    Hamed, Ahmed; Yousf, Fouad; Hussein, Mohamed M

    2017-03-01

    To determine the prevalence of mono-symptomatic nocturnal enuresis (MNE) and its risk factors among school-age children in our community. A cross-sectional study included school-age children from two governorates in south of Egypt. A questionnaire was presented to randomly selected students. It consisted of 3 domains: Domain 1 included questions about MNE, domain 2 was about risk factors for MNE, and domain 3 was about management of MNE. The study included 4652 students (9 ± 2 years) from 12 primary schools (51 % males and 49 % females). Of 4652 students, 834 (18 %) had NE, with no significant difference between rural and urban areas (17.5 vs. 18.4 %, p = 0.4). Younger age categories showed higher prevalence of MNE than in older children. MNE caused moderate-to-severe bother for 44.5 and 87.8 % of students and parents, respectively. Urinary tract infection, pinworm infestation, constipation, and caffeine over-consumption significantly associated with MNE. Family history of MNE was positive in 84.7 %. Daytime incontinence coexisted in 16 % of cases. Children with ≥4 siblings and birth order ≥3 had more prevalent MNE. Deep sleepers and exposure to problems/violence correlated positively with occurrence of MNE. Father's level of education and work status, mother education, number of children per room, and socioeconomic status significantly associated with occurrence of MNE. There was no significant correlation between gender and prevalence of MNE. No treatment was used in 53.2 % of cases. In the Egyptian community, pinworm infestation, UTI, constipation, and overconsumption of caffeine-containing beverages are potential reversible risk factors for MNE in school-age children.

  15. Sleep disorders and oral health: a cross-sectional study.

    Science.gov (United States)

    Carra, Maria Clotilde; Schmitt, Audrey; Thomas, Frederique; Danchin, Nicolas; Pannier, Bruno; Bouchard, Philippe

    2017-05-01

    Sleep disorders (SDs), particularly sleep deprivation, may alter the immune system and induce systemic inflammation. Recent evidence supports an association between SDs and periodontal diseases. This cross-sectional epidemiological study aims to compare oral health variables, such as the amount of plaque/calculus, gingival inflammation, and masticatory function, in individuals with and without SDs. The study population consisted in a French cohort of individuals who underwent medical and oral examinations between 2012 and 2013. Multivariate logistic regression and general linear models were used for group comparisons. Over a total of 29,870 individuals, 11,185 (37.4 %) reported to suffer from SDs on a regular basis. Compared to individuals without SDs, SD individuals were older (mean age 44.2 vs. 45.3 years; p < 0.0001), prevalently female (38.6 vs. 52.1 %; p < 0.0001), and with higher BMI (25.3 vs. 25.7; p < 0.0001). Moreover, SD individuals displayed a significantly higher prevalence of comorbidities, higher level of gingival inflammation (adjusted odds ratio 1.22 [95 % confidence interval 1.13-1.32]), and lower masticatory function (1.45 [1.33-1.58]). Short sleepers (<6 h of sleep/night) were found to be at an increased risk of gingival inflammation (1.25 [1.1-1.4]). SD individuals with moderate-to-high gingival inflammation showed a significantly increased risk of cardiovascular disease (1.39 [1.04-1.84]) compared to SD individuals with low or no gingival inflammation. Individuals with self-report SDs are at increased risk of gingival inflammation. The coexistence of SDs and gingival inflammation is associated with an increased risk of cardiovascular diseases. These findings provide evidence for an association between SDs and gingival inflammation and support further clinical and experimental studies.

  16. Molecular Phylogeny and Biogeography of the Amphidromous Fish Genus Dormitator Gill 1861 (Teleostei: Eleotridae)

    Science.gov (United States)

    Galván-Quesada, Sesángari; Doadrio, Ignacio; Alda, Fernando; Perdices, Anabel; Reina, Ruth Gisela; García Varela, Martín; Hernández, Natividad; Campos Mendoza, Antonio; Bermingham, Eldredge; Domínguez-Domínguez, Omar

    2016-01-01

    Species of the genus Dormitator, also known as sleepers, are representatives of the amphidromous freshwater fish fauna that inhabit the tropical and subtropical coastal environments of the Americas and Western Africa. Because of the distribution of this genus, it could be hypothesized that the evolutionary patterns in this genus, including a pair of geminate species across the Central American Isthmus, could be explained by vicariance following the break-up of Gondwana. However, the evolutionary history of this group has not been evaluated. We constructed a time-scaled molecular phylogeny of Dormitator using mitochondrial (Cytochrome b) and nuclear (Rhodopsin and β-actin) DNA sequence data to infer and date the cladogenetic events that drove the diversification of the genus and to relate them to the biogeographical history of Central America. Two divergent lineages of Dormitator were recovered: one that included all of the Pacific samples and another that included all of the eastern and western Atlantic samples. In contrast to the Pacific lineage, which showed no phylogeographic structure, the Atlantic lineage was geographically structured into four clades: Cameroon, Gulf of Mexico, West Cuba and Caribbean, showing evidence of potential cryptic species. The separation of the Pacific and Atlantic lineages was estimated to have occurred ~1 million years ago (Mya), whereas the four Atlantic clades showed mean times of divergence between 0.2 and 0.4 Mya. The splitting times of Dormitator between ocean basins are similar to those estimated for other geminate species pairs with shoreline estuarine preferences, which may indicate that the common evolutionary histories of the different clades are the result of isolation events associated with the closure of the Central American Isthmus and the subsequent climatic and oceanographic changes. PMID:27074006

  17. Sleep duration and consumption of sugar-sweetened beverages and energy drinks among adolescents.

    Science.gov (United States)

    Sampasa-Kanyinga, Hugues; Hamilton, Hayley A; Chaput, Jean-Philippe

    2018-04-01

    To examine the relationship between sleep duration and consumption of sugar sweetened beverages (SSBs) and energy drinks (EDs) among adolescents. Data on 9,473 adolescents aged 11-20 years were obtained from the 2015 cycle of the Ontario Student Drug Use and Health Survey, a province-wide and cross-sectional school based survey of students in middle and high school. Respondents self-reported their sleep duration and consumption of SSBs and EDs. Those who did not meet the age-appropriate sleep duration recommendation were considered short sleepers. Overall, 81.4% and 12.0% of respondents reported that they had at least one SSBs and EDs in the past week, respectively. Males were more likely than females to consume SSBs and EDs. High school students were more likely than those in middle school to report drinking EDs. After adjusting for multiple covariates, results from logistic regression analyses indicated that short sleep duration was associated with greater odds of SSB consumption in middle school students (odd ratio (OR) = 1.64, 95% confidence interval (CI) = 1.18-2.11), but not those in high school (OR = 1.06, 95% CI = 0.86-1.31). Short sleep duration was associated with greater odds of ED consumption in both middle (OR = 1.60, 95% CI = 1.10-2.34) and high school (OR = 1.78, 95% CI = 1.38-2.30) students. Short sleep duration was associated with consumption of EDs in middle and high school students and with SSBs in middle school students only. Future studies are needed to establish causality and to determine whether improving sleep patterns can reduce the consumption of SSBs and EDs among adolescents. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Associations among sleep disturbances, nocturnal sleep duration, daytime napping, and incident prediabetes and type 2 diabetes: the Heinz Nixdorf Recall Study.

    Science.gov (United States)

    Kowall, Bernd; Lehnich, Anna-Therese; Strucksberg, Karl-Heinz; Führer, Dagmar; Erbel, Raimund; Jankovic, Nicole; Moebus, Susanne; Jöckel, Karl-Heinz; Stang, Andreas

    2016-05-01

    Poor sleep quality as well as short and long sleep duration has been linked to type 2 diabetes. In addition to confirmational analyses, we examined the impact of daytime napping on incident diabetes, and we assessed associations between sleep characteristics and incident prediabetes. In a subgroup of the Heinz Nixdorf Recall Study, a population-based cohort study in Germany (N = 2962; age 45-75 years, without history of cancer, stroke, or cardiovascular diseases), diabetes at baseline and at 5-year follow-up was assessed by self-report and measurement of serum glucose levels. Prediabetes was defined as impaired fasting glucose (6.1-6.9 mmol/L). A sleep questionnaire was used to assess difficulties falling asleep, difficulties maintaining sleep, early morning arousal, and duration of nocturnal and daytime sleep. In adjusted regression models, short (≤5 hours) and long (≥7.5 hours) sleepers were at greater risk for diabetes (relative risk [RR] = 1.56, 95% confidence interval [CI] = 1.02-2.39, and 1.40, 95% CI = 1.01-1.96, respectively [reference: 7 hours]). Moreover, the prevalence of any regular sleep disorder was associated with incident diabetes (RR = 1.30, 95% CI = 1.01-1.68), and with incident prediabetes (RR = 1.31, 95% CI = 1.00-1.72). Regular daytime nappers had no increased risk of incident diabetes (RR = 1.00, 95% CI = 0.70-1.41). This study shows that people with regular sleep disorders, people with short and long sleep duration, but not regular daytime nappers are at increased risk of diabetes. Furthermore, regular sleep disorders are associated with an increased risk of prediabetes. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Moderators and Mediators of the Relationship Between Stress and Insomnia: Stressor Chronicity, Cognitive Intrusion, and Coping

    Science.gov (United States)

    Pillai, Vivek; Roth, Thomas; Mullins, Heather M.; Drake, Christopher L.

    2014-01-01

    Study Objectives: To assess moderators, such as stressor chronicity, and mediators, including stress response in the form of cognitive intrusion and coping behavior, of the prospective association between naturalistic stress and incident insomnia. Design: Longitudinal. Setting: Epidemiological. Participants: A community-based sample of good sleepers (n = 2,892) with no lifetime history of insomnia. Interventions: None. Measurements and Results: Participants reported the number of stressful events they had encountered at baseline, as well as the perceived severity and chronicity of each event. Similarly, volitional stress responses such as coping, as well as more involuntary responses such as cognitive intrusion were assayed for each stressor. Follow-up assessment 1 y hence revealed an insomnia incidence rate of 9.1%. Stress exposure was a significant predictor of insomnia onset, such that the odds of developing insomnia increased by 19% for every additional stressor. Chronicity significantly moderated this relationship, such that the likelihood of developing insomnia as a result of stress exposure increased as a function of chronicity. Cognitive intrusion significantly mediated the association between stress exposure and insomnia. Finally, three specific coping behaviors also acted as mediators: behavioral disengagement, distraction, and substance use. Conclusions: Most studies characterize the relationship between stress exposure and insomnia as a simple dose-response phenomenon. However, our data suggest that certain stressor characteristics significantly moderate this association. Stress response in the form of cognitive intrusion and specific maladaptive coping behaviors mediate the effects of stress exposure. These findings highlight the need for a multidimensional approach to stress assessment in future research and clinical practice. Citation: Pillai V, Roth T, Mullins HM, Drake CL. Moderators and mediators of the relationship between stress and insomnia

  20. Cognitive Performance, Sleepiness, and Mood in Partially Sleep Deprived Adolescents: The Need for Sleep Study.

    Science.gov (United States)

    Lo, June C; Ong, Ju Lynn; Leong, Ruth L F; Gooley, Joshua J; Chee, Michael W L

    2016-03-01

    To investigate the effects of sleep restriction (7 nights of 5 h time in bed [TIB]) on cognitive performance, subjective sleepiness, and mood in adolescents. A parallel-group design was adopted in the Need for Sleep Study. Fifty-six healthy adolescents (25 males, age = 15-19 y) who studied in top high schools and were not habitual short sleepers were randomly assigned to Sleep Restriction (SR) or Control groups. Participants underwent a 2-w protocol consisting of 3 baseline nights (TIB = 9 h), 7 nights of sleep opportunity manipulation (TIB = 5 h for the SR and 9 h for the control groups), and 3 nights of recovery sleep (TIB = 9 h) at a boarding school. A cognitive test battery was administered three times each day. During the manipulation period, the SR group demonstrated incremental deterioration in sustained attention, working memory and executive function, increase in subjective sleepiness, and decrease in positive mood. Subjective sleepiness and sustained attention did not return to baseline levels even after 2 recovery nights. In contrast, the control group maintained baseline levels of cognitive performance, subjective sleepiness, and mood throughout the study. Incremental improvement in speed of processing, as a result of repeated testing and learning, was observed in the control group but was attenuated in the sleep-restricted participants, who, despite two recovery sleep episodes, continued to perform worse than the control participants. A week of partial sleep deprivation impairs a wide range of cognitive functions, subjective alertness, and mood even in high-performing high school adolescents. Some measures do not recover fully even after 2 nights of recovery sleep. A commentary on this article appears in this issue on page 497. © 2016 Associated Professional Sleep Societies, LLC.

  1. Vibration energy harvesting in railway tunnels with a wireless sensor node application

    Energy Technology Data Exchange (ETDEWEB)

    Wischke, Martin

    2012-07-01

    Vibration harvesting is a promising concept to prolong the lifetime of batterypowered stand-alone systems, or even to enable their energy-autonomy. This thesis focuses on ambient vibrations converted by electromechanical transducers into electricity. The final goal is energy scavenging from train-induced vibrations in railway tunnels. This is achieved via the development of a suitable harvester for this environment and the practical demonstration of a vibrationpowered wireless sensor node (WSN). At the beginning of this thesis, extensive vibration measurements were performed in several traffic tunnels. The obtained unique data set formed the basis for the design and test of several harvesters. The railway sleeper was chosen as usable harvester location. A shock-resistant double-side suspended piezoelectric cantilever was developed. Several cantilevers with different eigenfrequencies are combined in an array, creating a robust harvester with a broad bandwidth. A field test of 7 days in the Loetschbergbasis-tunnel verified that, on average the sufficient energy for powering a virtual wireless sensor node was scavenged. For application in a real WSN, the harvester array was scaled up to 10 cantilevers. The power management for the sensor node was developed concurrently. The central component is a power switch that monitors the energy level in the system's storage capacitor and only triggers the wireless interface when sufficient energy is available. Combined with a train detection circuit, the presented energy-autonomous WSN reliably reports every passing vehicle. In addition to the development of an energy-autonomous fully integrated WSN, this work investigates nonlinear properties of PZT ceramics. Consideration of the elastostriction and the electrostriction enables a more precises prediction of the tip displacement of a piezoelectric cantilever actuator. Further, the elastostriction is exploited to modify the resonance frequency of a bimorph cantilever. Basing

  2. Экспресс-оценка и мониторинг показателей гемодинамики при проведении местной анестезии в терапевтической стоматологии

    OpenAIRE

    Серикова, О.; Елькова, Н.; Устин, А.; Овчинников, И.

    2012-01-01

    В статье представлены результаты исследования эффективности и безопасности различных видов местной анестезии, в том числе с применением электронной системы QuickSleeper. Программа экспресс-оценки эффективности и безопасности проводимой анестезии включает определение основных параметров гемодинамики, уровня глюкозы и кортизола крови....

  3. Neurobiological mechanisms involved in sleep bruxism.

    Science.gov (United States)

    Lavigne, G J; Kato, T; Kolta, A; Sessle, B J

    2003-01-01

    Sleep bruxism (SB) is reported by 8% of the adult population and is mainly associated with rhythmic masticatory muscle activity (RMMA) characterized by repetitive jaw muscle contractions (3 bursts or more at a frequency of 1 Hz). The consequences of SB may include tooth destruction, jaw pain, headaches, or the limitation of mandibular movement, as well as tooth-grinding sounds that disrupt the sleep of bed partners. SB is probably an extreme manifestation of a masticatory muscle activity occurring during the sleep of most normal subjects, since RMMA is observed in 60% of normal sleepers in the absence of grinding sounds. The pathophysiology of SB is becoming clearer, and there is an abundance of evidence outlining the neurophysiology and neurochemistry of rhythmic jaw movements (RJM) in relation to chewing, swallowing, and breathing. The sleep literature provides much evidence describing the mechanisms involved in the reduction of muscle tone, from sleep onset to the atonia that characterizes rapid eye movement (REM) sleep. Several brainstem structures (e.g., reticular pontis oralis, pontis caudalis, parvocellularis) and neurochemicals (e.g., serotonin, dopamine, gamma aminobutyric acid [GABA], noradrenaline) are involved in both the genesis of RJM and the modulation of muscle tone during sleep. It remains unknown why a high percentage of normal subjects present RMMA during sleep and why this activity is three times more frequent and higher in amplitude in SB patients. It is also unclear why RMMA during sleep is characterized by co-activation of both jaw-opening and jaw-closing muscles instead of the alternating jaw-opening and jaw-closing muscle activity pattern typical of chewing. The final section of this review proposes that RMMA during sleep has a role in lubricating the upper alimentary tract and increasing airway patency. The review concludes with an outline of questions for future research.

  4. Effects of nocturnal aircraft noise on sleep: results from the ''quiet air traffic'' project; Wirkungen des Nachtfluglaerms auf den Schlaf: Ergebnisse aus dem Projekt ''Leiser Flugverkehr''

    Energy Technology Data Exchange (ETDEWEB)

    Samel, A.; Basner, M.; Maass, H.; Mueller, U.; Quehl, J.; Wenzel, J. [Deutsches Zentrum fuer Luft- und Raumfahrt (DLR) in der Helmholtz-Gemeinschaft (HGF), Inst. fuer Luft- und Raumfahrtmedizin, Koeln (Germany)

    2005-07-01

    In 192 sleep-healthy subjects (18 to 65 y) effects of nocturnal aircraft noise on sleep, stress, performance and subjective factors were investigated in 2240 nights under laboratory and field conditions. In the sleep lab, 112 volunteers were subjected to aircraft noise events by varying numbers and noise levels during 9 nights within a period of 13 nights. 16 further subjects served as control group (i.e. without any noise). 64 subjects were studied in the vicinity of Cologne-Bonn airport during 9 nights. Polysomnographical and acoustical recordings, determination of excretion rates of stress hormones from night urines, performance tests and questionnaires were conducted during all days for the assessment of nocturnal aircraft noise effects. By simultaneous recording of electrophysiological and acoustical data the probability of noise induced awakenings was estimated. Performance and most of psychological parameters did not show significant dose-effect relationships, whereas annoyance did. Epinephrine and norepinephrine did not change under aircraft noise, cortisol did change only in the lab. In the lab, a comparison between all noisy nights and noise-free baseline nights exhibited a non-significant 2-min. reduction of sleep and a 4-min. decrease of slow-wave sleep. In the field, awakenings caused by aircraft noise were detected above a threshold of 33 dB(A) ''at the sleeper's ear''. All effects were much less pronounced in the field than in the lab. For the first time, precise dose-effect curves between maximum aircraft noise event levels and electrophysiologically detectable awakenings, and a threshold were empirically established. The results of these studies broadens the knowledge on aircraft noise induced sleep disturbances and immediate consequences for the next day. (orig.)

  5. Total sleep time severely drops during adolescence.

    Directory of Open Access Journals (Sweden)

    Damien Leger

    Full Text Available UNLABELLED: Restricted sleep duration among young adults and adolescents has been shown to increase the risk of morbidities such as obesity, diabetes or accidents. However there are few epidemiological studies on normal total sleep time (TST in representative groups of teen-agers which allow to get normative data. PURPOSE: To explore perceived total sleep time on schooldays (TSTS and non schooldays (TSTN and the prevalence of sleep initiating insomnia among a nationally representative sample of teenagers. METHODS: Data from 9,251 children aged 11 to 15 years-old, 50.7% of which were boys, as part of the cross-national study 2011 HBSC were analyzed. Self-completion questionnaires were administered in classrooms. An estimate of TSTS and TSTN (week-ends and vacations was calculated based on specifically designed sleep habits report. Sleep deprivation was estimated by a TSTN - TSTS difference >2 hours. Sleep initiating nsomnia was assessed according to International classification of sleep disorders (ICSD 2. Children who reported sleeping 7 hours or less per night were considered as short sleepers. RESULTS: A serious drop of TST was observed between 11 yo and 15 yo, both during the schooldays (9 hours 26 minutes vs. 7 h 55 min.; p<0.001 and at a lesser extent during week-ends (10 h 17 min. vs. 9 h 44 min.; p<0.001. Sleep deprivation concerned 16.0% of chidren aged of 11 yo vs. 40.5% of those of 15 yo (p<0.001. Too short sleep was reported by 2.6% of the 11 yo vs. 24.6% of the 15 yo (p<0.001. CONCLUSION: Despite the obvious need for sleep in adolescence, TST drastically decreases with age among children from 11 to 15 yo which creates significant sleep debt increasing with age.

  6. The community Noah land surface model with multiparameterization options (Noah-MP): 1. Model description and evaluation with local-scale measurements

    KAUST Repository

    Niu, Guo-Yue

    2011-06-24

    This first paper of the two-part series describes the objectives of the community efforts in improving the Noah land surface model (LSM), documents, through mathematical formulations, the augmented conceptual realism in biophysical and hydrological processes, and introduces a framework for multiple options to parameterize selected processes (Noah-MP). The Noah-MP\\'s performance is evaluated at various local sites using high temporal frequency data sets, and results show the advantages of using multiple optional schemes to interpret the differences in modeling simulations. The second paper focuses on ensemble evaluations with long-term regional (basin) and global scale data sets. The enhanced conceptual realism includes (1) the vegetation canopy energy balance, (2) the layered snowpack, (3) frozen soil and infiltration, (4) soil moisture-groundwater interaction and related runoff production, and (5) vegetation phenology. Sample local-scale validations are conducted over the First International Satellite Land Surface Climatology Project (ISLSCP) Field Experiment (FIFE) site, the W3 catchment of Sleepers River, Vermont, and a French snow observation site. Noah-MP shows apparent improvements in reproducing surface fluxes, skin temperature over dry periods, snow water equivalent (SWE), snow depth, and runoff over Noah LSM version 3.0. Noah-MP improves the SWE simulations due to more accurate simulations of the diurnal variations of the snow skin temperature, which is critical for computing available energy for melting. Noah-MP also improves the simulation of runoff peaks and timing by introducing a more permeable frozen soil and more accurate simulation of snowmelt. We also demonstrate that Noah-MP is an effective research tool by which modeling results for a given process can be interpreted through multiple optional parameterization schemes in the same model framework. Copyright © 2011 by the American Geophysical Union.

  7. Impact of Paint Color on Rest Period Climate Control Loads in Long-Haul Trucks: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Lustbader, J.; Kreutzer, C.; Jeffers, M.; Adelman, S.; Yeakel, S.; Brontz, P.; Olson, K.; Ohlinger, J.

    2014-02-01

    Cab climate conditioning is one of the primary reasons for operating the main engine in a long-haul truck during driver rest periods. In the United States, sleeper cab trucks use approximately 667 million gallons of fuel annually for rest period idling. The U.S. Department of Energy's National Renewable Energy Laboratory's (NREL) CoolCab Project works closely with industry to design efficient thermal management systems for long-haul trucks that minimize engine idling and fuel use while maintaining occupant comfort. Heat transfer to the vehicle interior from opaque exterior surfaces is one of the major heat pathways that contribute to air conditioning loads during long-haul truck daytime rest period idling. To quantify the impact of paint color and the opportunity for advanced paints, NREL collaborated with Volvo Group North America, PPG Industries, and Dometic Environmental Corporation. Initial screening simulations using CoolCalc, NREL's rapid HVAC load estimation tool, showed promising air-conditioning load reductions due to paint color selection. Tests conducted at NREL's Vehicle Testing and Integration Facility using long-haul truck cab sections, 'test bucks,' showed a 31.1% of maximum possible reduction in rise over ambient temperature and a 20.8% reduction in daily electric air conditioning energy use by switching from black to white paint. Additionally, changing from blue to an advanced color-matched solar reflective blue paint resulted in a 7.3% reduction in daily electric air conditioning energy use for weather conditions tested in Colorado. National-level modeling results using weather data from major U.S. cities indicated that the increase in heating loads due to lighter paint colors is much smaller than the reduction in cooling loads.

  8. The Crisis at Christmas Dental Service: a review of an annual volunteer-led dental service for homeless and vulnerably housed people in London.

    Science.gov (United States)

    Doughty, J; Stagnell, S; Shah, N; Vasey, A; Gillard, C

    2018-01-01

    Background The UK charity Crisis originated in 1967 as a response to the increasing numbers of homeless people in London, and the first Crisis at Christmas event for rough sleepers was established in 1971. Since then, Crisis has provided numerous services over the Christmas period to the most vulnerable members of society. One of these is the Crisis at Christmas Dental Service (CCDS) which provides emergency and routine dental care from 23-29 of December each year. The charity is entirely dependent on voluntary staffing and industry donations including materials and facilities. This paper aims to assess the impact of the service over the last six years of clinical activity from 2011-2016.Method Anonymised data were collected from the annual CCDS delivered over the last six consecutive years. Services included: dental consultations; oral hygiene instruction; scale and polishes; permanent fillings; extractions; and fluoride varnish applications. In addition, anonymised patient feedback was collected after each dental attendance.Results On average, 80-85% of the patients were male and the majority were between 21 and 60 years of age. The most common nationality was British (46%). Over the six-year data collection period intervention treatments (restorations and extractions) remained fairly consistent, while the number of fluoride varnish applications and oral hygiene instruction have increased. The majority of patients reported positive satisfaction with their treatment and would have recommended the service to others. Approximately 75% of patients did not regularly attend a dentist outside of Crisis and a similar proportion were given information on where to access year round dental services for homeless people in London. The majority of dental volunteers felt that they enjoyed the experience and would consider volunteering again for Crisis in the future.Conclusion The Crisis at Christmas Dental Service has emerged as a valuable asset to the portfolio of resources

  9. Burnout and Sleep Quality: A Cross-Sectional Questionnaire-Based Study of Medical and Non-Medical Students in India.

    Science.gov (United States)

    Shad, Rohan; Thawani, Rajat; Goel, Ashish

    2015-10-21

    Introduction It is well documented that on entering college, students experience a multitude of changes in sleep habits. Very few studies have been conducted that explore sleep quality in Indian undergraduate students; fewer still study the effects of burnout in the same population. Medical students, in particular, are believed to be more stressed, sleep deprived, and burnt out than their non-medical peers. Methods A cross-sectional study was conducted to study sleep disturbances and burnout in a sample of 214 Indian undergraduate students (112 medical, 102 non-medical). The instruments used to measure the sleep quality and burnout were the PSQI (Pittsburgh Sleep Quality Index) and OLBI (Oldenburg Burnout Inventory), respectively. Differences between continuous variables were analysed using Wilcox Mann Whitney U-tests. Bivariate Spearman's rho correlations were done to identify correlations between the individual burnout components and the PSQI sleep quality components. Results Of the students surveyed, 62.6% were found to be poor sleepers with an average score of 6.45 ± 2.85. It was seen that 20% of the students (n = 43) slept less than five hours a day. Medical students, in particular, were found to have more poor sleep (72.9%) than their non-medical peers (51.9%; p sleep scores (Rho 0.21, p 0.001) and (Rho = 0.18, p = 0.008), respectively. The exhaustion dimension of burnout was higher in medical students (2.46 ± 0.55) than in non-medical students (2.38 ± 0.59), but was seen to correlate more with the PSQI sleep score in the non-medical group (Rho = 0.62, p sleep scores, the burnout dimensions did not correlate well with the academic year. Conclusions Burnout and sleep quality are both uncommonly studied topics in India. Fostering a healthier and more proactive approach to tackling burnout and poor sleep quality may help unearth culture specific causes for some of the results we have demonstrated.

  10. Inter-comparison of hydro-climatic regimes across northern catchments: Synchronicity, resistance and resilience

    Science.gov (United States)

    Carey, S.K.; Tetzlaff, D.; Seibert, J.; Soulsby, C.; Buttle, J.; Laudon, H.; McDonnell, J.; McGuire, K.; Caissie, D.; Shanley, J.; Kennedy, M.; Devito, K.; Pomeroy, J.W.

    2010-01-01

    The higher mid-latitudes of the Northern Hemisphere are particularly sensitive to climate change as small differences in temperature determine frozen ground status, precipitation phase, and the magnitude and timing of snow accumulation and melt. An international inter-catchment comparison program, North-Watch, seeks to improve our understanding of the sensitivity of northern catchments to climate change by examining their hydrological and biogeochemical responses. The catchments are located in Sweden (Krycklan), Scotland (Mharcaidh, Girnock and Strontian), the United States (Sleepers River, Hubbard Brook and HJ Andrews) and Canada (Catamaran, Dorset and Wolf Creek). This briefing presents the initial stage of the North-Watch program, which focuses on how these catchments collect, store and release water and identify 'types' of hydro-climatic catchment response. At most sites, a 10-year data of daily precipitation, discharge and temperature were compiled and evaporation and storage were calculated. Inter-annual and seasonal patterns of hydrological processes were assessed via normalized fluxes and standard flow metrics. At the annual-scale, relations between temperature, precipitation and discharge were compared, highlighting the role of seasonality, wetness and snow/frozen ground. The seasonal pattern and synchronicity of fluxes at the monthly scale provided insight into system memory and the role of storage. We identified types of catchments that rapidly translate precipitation into runoff and others that more readily store water for delayed release. Synchronicity and variance of rainfall-runoff patterns were characterized by the coefficient of variation (cv) of monthly fluxes and correlation coefficients. Principal component analysis (PCA) revealed clustering among like catchments in terms of functioning, largely controlled by two components that (i) reflect temperature and precipitation gradients and the correlation of monthly precipitation and discharge and (ii

  11. Sociodemographic characteristics and waking activities and their role in the timing and duration of sleep.

    Science.gov (United States)

    Basner, Mathias; Spaeth, Andrea M; Dinges, David F

    2014-12-01

    Chronic sleep restriction is prevalent in the U.S. population and associated with increased morbidity and mortality. The primary reasons for reduced sleep are unknown. Using population data on time use, we sought to identify individual characteristics and behaviors associated with short sleep that could be targeted for intervention programs. Analysis of the American Time Use Survey (ATUS). Cross-sectional annual survey conducted by the U.S. Bureau of Labor Statistics. Representative cohort (N = 124,517) of Americans 15 years and older surveyed between 2003 and 2011. None. Telephone survey of activities over 24 hours. Relative to all other waking activities, paid work time was the primary waking activity exchanged for sleep. Time spent traveling, which included commuting to/ from work, and immediate pre- and post-sleep activities (socializing, grooming, watching TV) were also reciprocally related to sleep duration. With every hour that work or educational training started later in the morning, sleep time increased by approximately 20 minutes. Working multiple jobs was associated with the highest odds for sleeping ≤6 hours on weekdays (adjusted OR 1.61, 95% CI 1.44; 1.81). Self-employed respondents were less likely to be short sleepers compared to private sector employees (OR 0.83, 95% CI 0.72; 0.95). Sociodemographic characteristics associated with paid work (age 25-64, male sex, high income, and employment per se) were consistently associated with short sleep. U.S. population time use survey findings suggest that interventions to increase sleep time should concentrate on delaying the morning start time of work and educational activities (or making them more flexible), increasing sleep opportunities, and shortening morning and evening commute times. Reducing the need for multiple jobs may increase sleep time, but economic disincentives from working fewer hours will need to be offset. Raising awareness of the importance of sufficient sleep for health and safety may

  12. Water market transfers in South Africa: Two case studies

    Science.gov (United States)

    Nieuwoudt, W. L.; Armitage, R. M.

    2004-09-01

    Statistical analyses (discriminant, logit, and principal components) of water transfers in the Lower Orange River showed that water rights were transferred to farmers with the highest return per unit of water applied, those producing table grapes, and with high-potential arable "outer land" without water rights. Only unused water (sleeper right) was transferred, while water saved (through adoption of conservation practices) was retained possibly for security purposes. A second study in the Nkwaleni Valley in northern KwaZulu-Natal found that no water market had emerged despite the scarcity of water in the area. No willing sellers of water rights existed. Demand for institutional change to establish tradable water rights may take more time in the second area since crop profitability in this area is similar for potential buyers and nonbuyers. Transaction costs appear larger than benefits from market transactions. Farmers generally use all their water rights in the second area and retain surplus water rights as security against drought because of unreliable river flow. This study indicates that these irrigation farmers are highly risk averse (downside risk). Government policies that increase the level of risk and reduce security of licenses are estimated to have a significant effect on future investment in irrigation. In an investment model the following variables explain future investment: expected profits, liquidity, risk aversion (Arrow-Pratt), and security of water use rights. The study is seen in the light of the New South African Water Act of 1998. According to this act, the ownership of water in South Africa has changed from private to public. This reform may not impede the development of water markets in South Africa since in the well-developed water markets of the United States, western states claim ownership of water within their boundaries. All states in the western United States allow private rights in the use of water to be established and sold.

  13. Split-mouth and parallel-arm trials to compare pain with intraosseous anaesthesia delivered by the computerised Quicksleeper system and conventional infiltration anaesthesia in paediatric oral healthcare: protocol for a randomised controlled trial.

    Science.gov (United States)

    Smaïl-Faugeron, Violaine; Muller-Bolla, Michèle; Sixou, Jean-Louis; Courson, Frédéric

    2015-07-10

    Local anaesthesia is commonly used in paediatric oral healthcare. Infiltration anaesthesia is the most frequently used, but recent developments in anaesthesia techniques have introduced an alternative: intraosseous anaesthesia. We propose to perform a split-mouth and parallel-arm multicentre randomised controlled trial (RCT) comparing the pain caused by the insertion of the needle for the injection of conventional infiltration anaesthesia, and intraosseous anaesthesia by the computerised QuickSleeper system, in children and adolescents. Inclusion criteria are patients 7-15 years old with at least 2 first permanent molars belonging to the same dental arch (for the split-mouth RCT) or with a first permanent molar (for the parallel-arm RCT) requiring conservative or endodontic treatment limited to pulpotomy. The setting of this study is the Department of Paediatric Dentistry at 3 University dental hospitals in France. The primary outcome measure will be pain reported by the patient on a visual analogue scale concerning the insertion of the needle and the injection/infiltration. Secondary outcomes are latency, need for additional anaesthesia during the treatment and pain felt during the treatment. We will use a computer-generated permuted-block randomisation sequence for allocation to anaesthesia groups. The random sequences will be stratified by centre (and by dental arch for the parallel-arm RCT). Only participants will be blinded to group assignment. Data will be analysed by the intent-to-treat principle. In all, 160 patients will be included (30 in the split-mouth RCT, 130 in the parallel-arm RCT). This protocol has been approved by the French ethics committee for the protection of people (Comité de Protection des Personnes, Ile de France I) and will be conducted in full accordance with accepted ethical principles. Findings will be reported in scientific publications and at research conferences, and in project summary papers for participants. Clinical

  14. Urban and architectural risk factors for malaria in indigenous Amazonian settlements in Brazil: a typological analysis.

    Science.gov (United States)

    Leandro-Reguillo, Patricia; Thomson-Luque, Richard; Monteiro, Wuelton M; de Lacerda, Marcus V G

    2015-07-22

    In the Amazon, m alaria is highly endemic in indigenous populations, which are often considered one of the last barriers to malaria elimination due to geographic isolation. Although the improvement of housing conditions is a good strategy towards the control and prevention of vector-borne diseases, such as malaria, this preventive practice has been barely undertaken in Latin America. An analysis of the architectural and urban features of indigenous Amazonian populations is essential to define and adapt these vector control measures. A total of 32 villages of 29 different ethnicities were studied and mapped by reviewing literature and visual information, and using a geographic information system. The most important architectural and urban characteristics influencing malaria were analysed according to the following categories: number of households and dimensions, supporting area, openings, materials, lifespan and location. Housing typologies found were classified within each of these variables. The results of this typological analysis included an easy-to-handle working template and revealing of features that benefit or hamper the presence of malaria vectors in Amerindians communities. Among risk factors, presence of open eaves, permeable walls, open-side constructions, large number of sleepers indoors, temporary-ephemeral houses, linear villages along stream banks, houseboats villages, poor urban drainage and villages surrounded by anthropogenic environments were highlighted. Indigenous settlements very permissive for anophelines were identified in ethnic groups, such as the Yanomami, Palikur, Paumari, Waimiri-Atroari and Wajãpi. Positive features were also recognized, including opaque and closed houses, large radial villages on bare soil, highly elevated stilted houses and the fire indoors, found among the Yawalapiti, Ashaninka, and Gavião-Parkatejê tribes. However, as Amazonian indigenous settlement typologies vary greatly even among villages of the same ethnic

  15. A novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans.

    Science.gov (United States)

    Pellegrino, Renata; Kavakli, Ibrahim Halil; Goel, Namni; Cardinale, Christopher J; Dinges, David F; Kuna, Samuel T; Maislin, Greg; Van Dongen, Hans P A; Tufik, Sergio; Hogenesch, John B; Hakonarson, Hakon; Pack, Allan I

    2014-08-01

    Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loophelix family member e41) as causal in a family of short sleepers, who needed just 6 h sleep per night. We evaluated whether there were other variants of this gene in two well-phenotyped cohorts. Sequencing of the BHLHE41 gene, electroencephalographic data, and delta power analysis and functional studies using cell-based luciferase. We identified new variants of the BHLHE41 gene in two cohorts who had either acute sleep deprivation (n = 200) or chronic partial sleep deprivation (n = 217). One variant, Y362H, at another location in the same exon occurred in one twin in a dizygotic twin pair and was associated with reduced sleep duration, less recovery sleep following sleep deprivation, and fewer performance lapses during sleep deprivation than the homozygous twin. Both twins had almost identical amounts of non rapid eye movement (NREM) sleep. This variant reduced the ability of BHLHE41 to suppress CLOCK/BMAL1 and NPAS2/BMAL1 transactivation in vitro. Another variant in the same exome had no effect on sleep or response to sleep deprivation and no effect on CLOCK/BMAL1 transactivation. Random mutagenesis identified a number of other variants of BHLHE41 that affect its function. There are a number of mutations of BHLHE41. Mutations reduce total sleep while maintaining NREM sleep and provide resistance to the effects of sleep loss. Mutations that affect sleep also modify the normal inhibition of BHLHE41 of CLOCK/BMAL1 transactivation. Thus, clock mechanisms are likely involved in setting sleep length and the magnitude of sleep homeostasis. Pellegrino R, Kavakli IH, Goel N, Cardinale CJ, Dinges DF, Kuna ST, Maislin G, Van Dongen HP, Tufik S, Hogenesch JB, Hakonarson H, Pack AI. A novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans. SLEEP 2014;37(8):1327-1336.

  16. The Weakest Link: The Risks Associated with Social Networking Website

    Directory of Open Access Journals (Sweden)

    Yosef Lehrman

    2010-01-01

    Full Text Available The relatively rapid rise in popularity of social networking services is now well known. MySpace, Twitter, and Facebook have become well known sites and terms. According to the Web traffic tracking site Alexa.com, as of December 2009, Facebook had 350 million registered users, MySpace just under 475 million, and Twitter 44.5 million. Many people think very little of posting prodigious amounts of personal information on social networking sites, not realizing that this information puts them at risk. Specifically, those in the law enforcement and military communities may not realize that information posted on these sites can compromise operational security and potentially endanger lives. In July 2009, the Associated Press ran a story which was picked up by most major news outlets in the USA, in which it was reported that the wife of the incoming head of Britain's MI6 intelligence agency had posted pictures and family details on her Facebook page. Astonishingly, there were those that argued that this was not a security breach! Although it is true that, in general, photos of a vacationing family would not be considered sensitive, when you consider that the family taking the vacation includes the head of the British foreign intelligence service, it is easy to see how this kind of exposure could open the door to potential blackmail.We are all too aware of the possibility of terrorist "sleeper cells" living among typical American families under false identities. It is vital to understand how these individuals melt into the crowd, hiding their true identities while they hatch their nefarious plots. Recent events in Denver and New York City only serve to underscore the urgency of this need. This article will examine social networking in the context of social engineering. There are no easy or fast solutions to this problem, and this paper does not pretend to propose any. Rather, it is the purpose of this paper to enhance understanding of this very critical

  17. Forest Dynamics in the Eastern Ghats of Tamil Nadu, India

    Science.gov (United States)

    Jayakumar, S.; Ramachandran, A.; Bhaskaran, G.; Heo, J.

    2009-02-01

    The primary deciduous forests in the Eastern Ghats (EG) of Tamil Nadu (TN) India have undergone many changes owing to various need-based forest managements, such as timber extraction for industry, railway sleepers, charcoal, and forest clearance for hydroelectric projects and agriculture, during preindependence and postindependence periods (i.e., from 1800 to 1980). The enactment of a forest conservation act during the 1980s changed the perception of forest managers from utilization to conservation. This study was taken up to assess the forests dynamics in the EG of TN spatially between 1990 and 2003 and nonspatially between 1900 and the 1980s. Landsat Thematic Mapper (TM) and Indian Remote Sensing satellite (IRS) 1D Linear Imaging and Self Scanning (LISS III) data were used to assess forests during 1990 and 2003, respectively. Field floristic survey and secondary data (such as published literature, floras, books, and forest working plans) were used to assess the forest dynamics in terms of forest type and species composition among the preindependence period, the postindependence period, and the present (i.e., before and after 1980). The satellite data analysis revealed a considerable amount of changes in all forest types during the 13 years. The comparison of species composition and forest types between the past and present revealed that need-based forest management along with anthropogenic activity have altered the primary deciduous forest in to secondary and postextraction secondary forests such as southern thorn and southern thorn scrub forests in the middle [400-900 m above mean sea level (MSL)] and lower slopes (900 m MSL) and plateau seemed not to be much affected by the forest management. The changes estimated by the satellite data processing in the major forest types such as evergreen, deciduous, southern thorn, and southern thorn scrub are really alarming because these changes have occurred after the implementation of a forest conservation act. The

  18. Bed-sharing in the absence of hazardous circumstances: is there a risk of sudden infant death syndrome? An analysis from two case-control studies conducted in the UK.

    Directory of Open Access Journals (Sweden)

    Peter S Blair

    Full Text Available The risk of sudden infant death syndrome (SIDS among infants who co-sleep in the absence of hazardous circumstances is unclear and needs to be quantified.Combined individual-analysis of two population-based case-control studies of SIDS infants and controls comparable for age and time of last sleep.Parents of 400 SIDS infants and 1386 controls provided information from five English health regions between 1993-6 (population: 17.7 million and one of these regions between 2003-6 (population:4.9 million.Over a third of SIDS infants (36% were found co-sleeping with an adult at the time of death compared to 15% of control infants after the reference sleep (multivariate OR = 3.9 [95% CI: 2.7-5.6]. The multivariable risk associated with co-sleeping on a sofa (OR = 18.3 [95% CI: 7.1-47.4] or next to a parent who drank more than two units of alcohol (OR = 18.3 [95% CI: 7.7-43.5] was very high and significant for infants of all ages. The risk associated with co-sleeping next to someone who smoked was significant for infants under 3 months old (OR = 8.9 [95% CI: 5.3-15.1] but not for older infants (OR = 1.4 [95% CI: 0.7-2.8]. The multivariable risk associated with bed-sharing in the absence of these hazards was not significant overall (OR = 1.1 [95% CI: 0.6-2.0], for infants less than 3 months old (OR = 1.6 [95% CI: 0.96-2.7], and was in the direction of protection for older infants (OR = 0.1 [95% CI: 0.01-0.5]. Dummy use was associated with a lower risk of SIDS only among co-sleepers and prone sleeping was a higher risk only among infants sleeping alone.These findings support a public health strategy that underlines specific hazardous co-sleeping environments parents should avoid. Sofa-sharing is not a safe alternative to bed-sharing and bed-sharing should be avoided if parents consume alcohol, smoke or take drugs or if the infant is pre-term.

  19. The effect of track load correlation on ground-borne vibration from railways

    Science.gov (United States)

    Ntotsios, Evangelos; Thompson, David; Hussein, Mohammed

    2017-08-01

    In predictions of ground-borne vibration from railways, it is generally assumed that the unevenness profile of the wheel and rail is fully correlated between the two rails and the two wheels of an axle. This leads to identical contact forces at the two rails and can allow further simplifications of the vehicle model, the track model and the track/ground interface conditions. In the present paper, the level of correlation of the track loading at the wheel/rail interface due to rail unevenness and its influence on predictions of ground vibration is investigated. The extent to which the unevenness of the two rails is correlated has been estimated from measurements of track geometry obtained with track recording vehicles for four different tracks. It was found that for wavelengths longer than about 3 m the unevenness of the two rails can be considered to be strongly correlated and in phase. To investigate the effect of this on ground vibration, an existing model expressed in the wavenumber-frequency domain is extended to include separate inputs on the two rails. The track is modelled as an infinite invariant linear structure resting on an elastic stratified half-space. This is excited by the gravitational loading of a passing train and the irregularity of the contact surfaces between the wheels and the rails. The railway model is developed in this work to be versatile so that it can account or discard the effect of load correlations on the two rails beside the effects of variation of the tractions across the width of the track-ground interface and the vehicle sprung mass, as well as the roll motion of the sleepers and the axle. A comparative analysis is carried out on the influence of these factors on the response predictions using numerical simulations. It is shown that, when determining the vibration in the free field, it is important to include in the model the traction variation across the track-ground interface and the non-symmetrical loading at the two rails that

  20. Technological changes illustrated by the coal tar and tar dye industry; Die Wandlung der Technik am Beispiel der Steinkohlenteer- und Teerfarben-Chemie

    Energy Technology Data Exchange (ETDEWEB)

    Collin, G. [Deutsche Gesellschaft fuer Chemisches Apparatewesen, Chemische Technik und Biotechnologie e.V. (DECHEMA), Frankfurt am Main (Germany)

    2001-05-01

    Coal tar was detected in the 17th century in laboratory experiments based on empirical knowledge. In the 18th century industrial revolution, coal tar was an undesired by-product of iron production and coking plants. It was first used in the 19th century for impregnating railway sleepers. Later developments in atomic theory, new chemical symbols and organic element analysis provided the basis for discovering and chemical characterisation of coal tar constituents. Laboratory experiments with these tar constituents resulted in the first synthetic dyes, the postulation of tetravalent carbon and the resulting structural theory in organic chemistry for systematic synthesis of many tar dyes to substitute natural dyes in the textile industry. The technical application of these syntheses was part 2 of the industrial revolution and the foundation of the chemical industry in Germany, which developed rapidly in the 2nd half of the 19th century. Tar dye chemistry has made a significant contribution to Germany's economic growth and the change from an agricultural to an industrialized country. [German] Die Entdeckung des Steinkohlenteers im 17. Jahrhundert basiert auf durch Erfahrungswissen gepraegten Laboratoriumsexperimenten. Im Verlauf der 'Industriellen Revolution' des 18. Jahrhunderts ist der Steinkohlenteer zunaechst ein laestiges Abfallprodukt der Eisengewinnung im Kokshochofen und der Leuchtgasherstellung durch Kohlenverkokung. Erste technische Applikation finden Steinkohlenteeroele im 19. Jahrhundert durch den Eisenbahnbau zur Langzeit-Konservierung der dafuer benoetigten Holzschwellen. Die wissenschaftlichen Erfkenntnisse zur Atomtheorie, eine neue chemische Zeichensprache und die organische Elementaranalyse werden Voraussetzungen zur Entdeckung und chemischen Charakterisierung der Hauptinhaltsstoffe des Steinkohlenteers. Laboratoriumsexperimente mit den entdeckten Teerinhaltsstoffen fuehren zur Erfindung der ersten synthetischen Farbstoffe, die

  1. Clinical Update on Epidemiology, Pathogenesis, and Nonpharmacological Treatment of Insomnia

    Directory of Open Access Journals (Sweden)

    Mustafa Kahriman

    2006-04-01

    30% of patients become completely symptom free and can be called as "good sleepers". The clinical studies showed that sleep improvements are well maintained up to 2 years after treatment completion. C o n c l u s i o n: Despite evidence showing psychological and behavioral approaches to be efficacious in the treatment of insomnia, in today’s clinical practice, such therapies are not readily available and are not widely used by doctors

  2. Anatomía y usos de la madera de ocho especies tropicales de Quintana Roo, México

    Directory of Open Access Journals (Sweden)

    Silvia Rebollar

    1998-12-01

    Full Text Available Se estudió la anatomía de la madera de ocho especies procedentes de asociaciones secundarias de las selvas alta y mediana subperennifolia del estado de Quintana Roo: Acacia gaumeri, Diphysa carthagenensis Gliricidia sepium, Leucaena glauca, Senna racemosa, Murraya paniculata, Maytenus guatemalensis, y Pimenta dioica, de acuerdo con la metodología establecida. Son especies de interés por su distribución, abundancia en el estado, y por los usos que tradicionalmente les han dado los campesinos mayas en postería, cercas, construcción rural durmintes, tablones y leña, debido a las cualidades de dureza y resistencia a la humedad y a los insectos. Las especies presentan porosidad difusa, los vasos con puntuaciones areoladas opuestas y alternas, la placa perforada es simple; el parénquima axial se presenta aliforme y en bandas; con cristales en todas las especies a excepción de Acacia gaumeri y Senna racemosa. Los rayos son bajos finos y numerosos; las fibras son de tipo libriforme. Las diferencias encontradas son: el arreglo de los poros, tipo de parénquima axial y radial, la presencia de fibrotraqueidas y traqueidas vasculares y tílides.This paper describes the wood anatomy of Acacia gaumeri Blake, Diphysa carthagenensis Jacq., Gliricidia sepium (Jacq. Steud., Leucaena glauca (L. Benth., Senna racemosa (Mill Irwin & Barneby, Murraya paniculata L.Mant., Maytenus guatemalensis Lundell, and Pimenta dioica (L. Merr. These species are aesthetically attractive as well as hard, highly durable and resistant to insects and locally are widely used in posts, fences, sleepers and rural buildings. Samples were collected from the rainforest in Quintana Roo, Mexico. One tree for each species was collected, and macroscopic and microscopic characteristics were described and measured in wood samples, permanent slides and macerated material. Woods have diffuse porosity, simple perforation plates, alternate and opposite vessel pits and small rays. Crystals

  3. Sociodemographic Characteristics and Waking Activities and their Role in the Timing and Duration of Sleep

    Science.gov (United States)

    Basner, Mathias; Spaeth, Andrea M.; Dinges, David F.

    2014-01-01

    Study Objectives: Chronic sleep restriction is prevalent in the U.S. population and associated with increased morbidity and mortality. The primary reasons for reduced sleep are unknown. Using population data on time use, we sought to identify individual characteristics and behaviors associated with short sleep that could be targeted for intervention programs. Design: Analysis of the American Time Use Survey (ATUS). Setting: Cross-sectional annual survey conducted by the U.S. Bureau of Labor Statistics. Participants: Representative cohort (N = 124,517) of Americans 15 years and older surveyed between 2003 and 2011. Interventions: None. Measurements and Results: Telephone survey of activities over 24 hours. Relative to all other waking activities, paid work time was the primary waking activity exchanged for sleep. Time spent traveling, which included commuting to/from work, and immediate pre- and post-sleep activities (socializing, grooming, watching TV) were also reciprocally related to sleep duration. With every hour that work or educational training started later in the morning, sleep time increased by approximately 20 minutes. Working multiple jobs was associated with the highest odds for sleeping ≤ 6 hours on weekdays (adjusted OR 1.61, 95% CI 1.44; 1.81). Self-employed respondents were less likely to be short sleepers compared to private sector employees (OR 0.83, 95% CI 0.72; 0.95). Sociodemographic characteristics associated with paid work (age 25-64, male sex, high income, and employment per se) were consistently associated with short sleep. Conclusions: U.S. population time use survey findings suggest that interventions to increase sleep time should concentrate on delaying the morning start time of work and educational activities (or making them more flexible), increasing sleep opportunities, and shortening morning and evening commute times. Reducing the need for multiple jobs may increase sleep time, but economic disincentives from working fewer hours

  4. Sleep habits and pattern in 1-14 years old children and relationship with video devices use and evening and night child activities.

    Science.gov (United States)

    Brambilla, Paolo; Giussani, Marco; Pasinato, Angela; Venturelli, Leonello; Privitera, Francesco; Miraglia Del Giudice, Emanuele; Sollai, Sara; Picca, Marina; Di Mauro, Giuseppe; Bruni, Oliviero; Chiappini, Elena

    2017-01-13

    Sleep in childhood and adolescence is crucial for mental and physical health; however several researches reported an increasing trend towards a sleep deprivation in this age. Due to the lack of recent epidemiological studies in Italy, the aim of our study was to depict sleep habits and patterns in Italian children aged 1-14 years and to evaluate their relationships with video devices use (TV, tablet, smartphone, PC) and evening/night child activities. A structured interview was conducted during 2015 by 72 Family Pediatricians in 2030 healthy children aged 1-14 years by a cross-sectional survey named "Ci piace sognare". Total sleep duration was calculated, 2015 National Sleep Foundation Recommendations were used as reference. Optimal sleepers were defined children sleeping in own bed all night without awakenings. Multivariable median regression was performed to identify predictors of sleep duration and multivariable logistic regression for predictors of optimal sleep. Total sleep duration and numbers of awakenings decreased with age. Only 66.9% of children had sleep duration in agreement with Recommendations (50% in 10-14 years group). Before sleeping 63.5% of children used video devices (39.6% at 1-3 years), 39.1% read, 27.5% drank and 19.5% ate. Bottle users at bedtime were 30.8% at 1-3 years, 16.6% at 3-5 years and 4.9% at 5-7 years. Overall, 23.4% of children changed sleeping place during the night, 22.4% referred sleeping problems in the first year of life. Video devices use was negative predictor of sleep duration (-0.25 h [95%CI:-0.35,-0.14], p sleep was inversely related with bedroom TV (OR 0.63 [0.50,0.79], p sleeping disorders in the first year (OR 0.62 [0.48,0.80], p sleep less than recommended, one half in teenage. Modifiable risk factors for sleep abnormalities such as video devices use, bedroom TV and bottle use should be target of preventive strategies for a correct sleep. Pediatricians should give priority to the identification of sleep

  5. Day and night shift schedules are associated with lower sleep quality in Evening-types.

    Science.gov (United States)

    Martin, Jeanne Sophie; Laberge, Luc; Sasseville, Alexandre; Bérubé, Marilie; Alain, Samuel; Houle, Jérôme; Hébert, Marc

    2015-06-01

    Eveningness has been suggested as a facilitating factor in adaptation to shift work, with several studies reporting evening chronotypes (E-types) as better sleepers when on night shifts. Conversely, eveningness has been associated with more sleep complaints during day shifts. However, sleep during day shifts has received limited attention in previous studies assessing chronotypes in shift workers. Environmental light exposure has also been reported to differ between chronotypes in day workers. Activity is also known to provide temporal input to the circadian clock. Therefore, the aim of this study was to compare objective sleep, light exposure and activity levels between chronotypes, both during the night and day shifts. Thirty-nine patrol police patrol officers working on a fast rotating shift schedule (mean age ± SD: 28.9 ± 3.2 yrs; 28 males) participated in this study. All subjects completed the Morningness-Eveningness Questionnaire (MEQ). Sleep and activity were monitored with actigraphy (Actiwatch-L; Mini-Mitter/Respironics, Bend, OR) for four consecutive night shifts and four consecutive day shifts (night work schedule: 00:00 h-07:00 h; day work schedule: 07:00 h-15:00 h). Sleep and activity parameters were calculated with Actiware software. MEQ scores ranged from 26 to 56; no subject was categorized as Morning-type. E-types (n = 13) showed significantly lower sleep efficiency, longer snooze time and spent more time awake after sleep onset than Intermediate-types (I-types, n = 26) for both the night and day shifts. E-types also exhibited shorter and more numerous sleep bouts. Furthermore, when napping was taken into account, E-types had shorter total sleep duration than I-types during the day shifts. E-types were more active during the first hours of their night shift when compared to I-types. Also, all participants spent more time active and had higher amount of activity per minute during day shifts when compared to night shifts. No

  6. Predictors of poor sleep quality among Lebanese university students: association between evening typology, lifestyle behaviors, and sleep habits

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    Kabrita CS

    2014-01-01

    Full Text Available Colette S Kabrita,1 Theresa A Hajjar-Muça,2 Jeanne F Duffy31Department of Sciences, 2Department of Mathematics and Statistics, Faculty of Natural and Applied Sciences, Notre Dame University – Louaize, Zouk Mosbeh, Lebanon; 3Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USAAbstract: Adequate, good night sleep is fundamental to well-being and is known to be influenced by myriad biological and environmental factors. Given the unavailability of sleep data about Lebanon, the cultural shifts and socioeconomic pressures that have affected many aspects of society, particularly for students and working adults, as well as our understanding of sleep in university students in other countries, we conducted a national study to assess sleep quality and factors contributing to sleep and general health in a culture-specific context. A self-filled questionnaire, inquiring about sociodemographics, health-risk behaviors, personal health, and evaluating sleep quality and chronotype using standard scales was completed by 540 students at private and public universities in Lebanon. Overall, they reported sleeping 7.95±1.34 hours per night, although 12.3% reported sleeping <6.5 hours and more than half scored in the poor-sleeper category on the Pittsburgh Sleep Quality Index (PSQI. Sleep timing differed markedly between weekdays and weekends, with bedtimes and wake-up times delayed by 1.51 and 2.43 hours, respectively, on weekends. While most scored in the "neither type" category on the Morningness–Eveningness Questionnaire (MEQ, 24.5% were evening types and 7.3% were morning types. MEQ score was significantly correlated with smoking behavior and daily study onset, as well as with PSQI score, with eveningness associated with greater number of cigarettes, later study times, and poor sleep. We conclude that the prevalence of poor sleep quality among Lebanese university students is associated

  7. Stress and sleep quality in high school brazilian adolescents

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    Gema Mesquita

    2010-06-01

    Full Text Available OBJECTIVE: The objective of the present study is to analyze the effect of stress on sleep quality in a group of adolescents. METHOD: Two high schools in Alfenas, southern Minas Gerais State, Brazil, were chosen to participate in the study. The sample consisted of both genders (n=160 with 65.63% females. The age range of participants was 15 to18 years. The Pittsburgh Sleep Quality Index (PSQI was applied for collection of data to quantify sleep quality. The Lipp Inventory of Stress Symptoms that objectively identifies symptoms of stress was applied. RESULTS: It was observed that 23.53% of stressed students and 45.33% of unstressed ones sleep well; 76.47% of stressed pupils and 54.67% of those unstressed do not sleep well. With regard to school performance, a mean of 0.65 was found for stressed students and 0.60 for those without stress, Mann-Whitney (p=0.0596. CONCLUSION: Stress contributed to raising the percentage of poor sleepers, as ell as increasing ean school performance.OBJETIVO: O objetivo do presente estudo foi analisar a influência do stress sobre a qualidade do sono em um grupo de adolescentes. MÉTODO: Foram escolhidas duas instituições educacionais do ensino médio, na cidade de Alfenas, sul de Minas Gerais, Brasil. A amostra foi composta por ambos os sexos (n=160, com 65,63% do sexo feminino. A faixa etária dos participantes foi de 15 a 18 anos. Para a coleta de dados aplicou-se: Índice de Qualidade de Sono de Pittsburgh (IQSP utilizado para quantificar a qualidade do sono; o Inventário de Sintomas de Stress para Adultos de Lipp (ISSL que identifica de modo objetivo a sintomatologia de stress foi aplicado. RESULTADOS: Observou-se que 23,53% dos estressados dormem bem e 45,33% dos não estressados dormem bem; 76,47% dos estressados não dormem bem e 54,67% dos não estressados não dormem bem. Quanto ao rendimento escolar têm-se as médias 0,65 para os alunos estressados e 0,60 para aqueles que não sofrem de stress, Mann

  8. Performance evaluation of an automated single-channel sleep–wake detection algorithm

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    Kaplan RF

    2014-10-01

    Full Text Available Richard F Kaplan,1 Ying Wang,1 Kenneth A Loparo,1,2 Monica R Kelly,3 Richard R Bootzin3 1General Sleep Corporation, Euclid, OH, USA; 2Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, USA; 3Department of Psychology, University of Arizona, Tucson, AZ, USA Background: A need exists, from both a clinical and a research standpoint, for objective sleep measurement systems that are both easy to use and can accurately assess sleep and wake. This study evaluates the output of an automated sleep–wake detection algorithm (Z-ALG used in the Zmachine (a portable, single-channel, electroencephalographic [EEG] acquisition and analysis system against laboratory polysomnography (PSG using a consensus of expert visual scorers. Methods: Overnight laboratory PSG studies from 99 subjects (52 females/47 males, 18–60 years, median age 32.7 years, including both normal sleepers and those with a variety of sleep disorders, were assessed. PSG data obtained from the differential mastoids (A1–A2 were assessed by Z-ALG, which determines sleep versus wake every 30 seconds using low-frequency, intermediate-frequency, and high-frequency and time domain EEG features. PSG data were independently scored by two to four certified PSG technologists, using standard Rechtschaffen and Kales guidelines, and these score files were combined on an epoch-by-epoch basis, using a majority voting rule, to generate a single score file per subject to compare against the Z-ALG output. Both epoch-by-epoch and standard sleep indices (eg, total sleep time, sleep efficiency, latency to persistent sleep, and wake after sleep onset were compared between the Z-ALG output and the technologist consensus score files. Results: Overall, the sensitivity and specificity for detecting sleep using the Z-ALG as compared to the technologist consensus are 95.5% and 92.5%, respectively, across all subjects, and the positive predictive value and the

  9. Primary nocturnal enuresis in children. Background and treatment.

    Science.gov (United States)

    Wille, S

    1994-01-01

    The aim of the present studies was to investigate background factors and treatment in children with monosymptomatic primary nocturnal enuresis. The study material comprised enuretics, former enuretics and controls from the municipal community of Falkenberg on the west coast of Sweden. Whenever possible all investigations were made with the children staying in their own home environment. Different background factors have been suspected as being causative: sleep disturbances, behavioural or psychological disturbances, small bladder capacity, increased night diuresis and an insufficient production of the antidiuretic hormone during sleep. These factors have been investigated in these studies. The treatment of enuresis has been dominated by the alarm and antidiuretic treatment with DDAVP. Primary nocturnal monosymptomatic enuresis is a common problem in childhood. In this study the prevalence among 392 seven year old children was 7.3%. A prior history of enuresis was found in 65% of families of the enuretics compared to 25% in controls. The enuretic children showed no statistically significant differences in behavioural or psychological problems compared to non-enuretic children. Enuretic children were described as heavy sleepers by their parents and a wake-up test performed at home showed that they were statistically significantly harder to arouse than the controls. Children with nocturnal enuresis, former enuretics and controls did not differ in social or behavioural traits in an interview study. No signs of symptom substitution was found when enuresis was resolved. Enuretic children had a normal bladder capacity and no statistically significant difference was found compared to controls and former enuretics. The enuretic children showed a normal calcium-creatinine quota in the urine. Former enuretic children showed a significantly enhanced calcium/creatinine quota compared to enuretics and controls. Enuretic children had a statistically significant lower morning

  10. Altered intrinsic regional brain activity in male patients with severe obstructive sleep apnea: a resting-state functional magnetic resonance imaging study

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    Peng DC

    2014-09-01

    Full Text Available De-Chang Peng,1 Xi-Jian Dai,1,2 Hong-Han Gong,1 Hai-Jun Li,1 Xiao Nie,1 Wei Zhang3 1Department of Radiology, The First Affiliated Hospital of Nanchang University, Jiangxi, 2Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region, 3Department of Pneumology, The First Affiliated Hospital of Nanchang University, Jiangxi, People’s Republic of China Background: Previous studies have demonstrated that obstructive sleep apnea (OSA is associated with abnormal brain structural deficits. However, little is known about the changes in local synchronization of spontaneous activity in patients with OSA. The primary aim of the present study was to investigate spontaneous brain activity in patients with OSA compared with good sleepers (GSs using regional homogeneity (ReHo analysis based on resting-state ­functional magnetic resonance imaging (MRI. Methods: Twenty-five untreated male patients with severe OSA and 25 male GSs matched for age and years of education were included in this study. The ReHo method was calculated to assess the strength of local signal synchrony and was compared between the two groups. The observed mean ReHo values were entered into Statistical Package for the Social Sciences software to assess their correlation with behavioral performance. Results: Compared with GSs, patients with OSA showed significantly lower ReHo in the right medial frontal gyrus (BA11, right superior frontal gyrus (BA10, right cluster of the precuneus and angular gyrus (BA39, and left superior parietal lobule (BA7, and higher ReHo in the right posterior lobe of the cerebellum, right cingulate gyrus (BA23, and bilateral cluster covering the lentiform nucleus, putamen, and insula (BA13. The lower mean ReHo value in the right cluster of the precuneus and angular gyrus had a significant negative correlation with sleep time (r=-0.430, P=0.032, and higher ReHo in

  11. Neuropsychiatry at the Courtroom Gates: Selective Entry or Anything Goes?

    Science.gov (United States)

    Brakel; Gonzalez; Cavanaugh

    1996-07-01

    That the influx of technology into our lives will include its entry into law and legal proceedings is a foregone conclusion. "Progress" of this kind can be slowed or regulated, perhaps, but it cannot be stopped. The proposed use of positron emission tomography (PET) scan-derived data on brain functioning in a criminal insanity case is merely one of the latest efforts to put biotechnology to forensic use. How the court reacts to this particular admissibility proposition-in or out?-may serve as a useful example of how the larger battle is fought. Trial judges are the gatekeepers in our legal system. They make the initial decision as to whether a piece of controversial evidence, scientific or otherwise, may go to the jury. Trial judges are under pressure to admit innovative factual evidence or theory from several sources, among which trial attorneys, the purveyors and practitioners of the new techniques, and the law itself (as personified by the "progressive" rulings of appellate judges or legislators) are the more obvious. The 1975 Federal Rules of Evidence exemplify the success of this sort of pressure. Pertaining to the admissibility of evidence generally and of scientific evidence in particular, the Federal Rules are clearly more liberal in intent and effect than was the doctrine that preceeded them: the 1923 Frye rule, which required "general acceptance" of the proffered new technology or theory. In the recent case of Daubert v. Merrell Dow Pharmaceuticals, however, the U.S. Supreme Court has let it be known that standards of reliability continue to be in force for scientific evidence submitted under the Federal Rules and that gatekeeping remains an important function of the trial judge. Nonetheless, a "sleeper" rule permitting experts to support the opinions they offer in court with reasonable clarifying information opens the evidentiary door a bit wider than the restrictions of Daubert might suggest. In the case at hand, this rule led to a preliminary decision

  12. The underlying reasons for very high levels of bed net use, and higher malaria infection prevalence among bed net users than non-users in the Tanzanian city of Dar es Salaam: a qualitative study.

    Science.gov (United States)

    Msellemu, Daniel; Shemdoe, Aloysia; Makungu, Christina; Mlacha, Yeromini; Kannady, Khadija; Dongus, Stefan; Killeen, Gerry F; Dillip, Angel

    2017-10-23

    Bed nets reduce malaria-related illness and deaths, by forming a protective barrier around people sleeping under them. When impregnated with long-lasting insecticide formulations they also repel or kill mosquitoes attempting to feed upon sleeping humans, and can even suppress entire populations of malaria vectors that feed predominantly upon humans. Nevertheless, an epidemiological study in 2012 demonstrated higher malaria prevalence among bed net users than non-users in urban Dar es Salaam, Tanzania. Focus group discussions were conducted with women from four selected wards of Dar es Salaam city, focusing on four major themes relating to bed net use behaviours: (1) reasons for bed net use, (2) reasons for not using bed nets, (3) stimuli or reminders for people to use a bed net (4) perceived reasons for catching malaria while using a bed net. An analytical method by framework grouping of relevant themes was used address key issues of relevance to the study objectives. Codes were reviewed and grouped into categories and themes. All groups said the main reason for bed net use was protection against malaria. Houses with well-screened windows, with doors that shut properly, and that use insecticidal sprays against mosquitoes, were said not to use bed nets, while frequent attacks from malaria was the main stimulus for people to use bed nets. Various reasons were mentioned as potential reasons that compromise bed net efficacy, the most common of which were: (1) bed net sharing by two or more people, especially if one occupant tends to come to bed late at night, and does not tuck in the net 71%; (2) one person shares the bed but does not use the net, moving it away from the side on which s/he sleeps 68%; (3) ineffective usage habits, called ulalavi, in which a sprawling sleeper either touches the net while sleeping up against it or leaves a limb hanging outside of it 68%. Less common reasons mentioned included: (1) Small bed nets which become un-tucked at night (31%); (2

  13. [Infants' attachment security in a vulnerable French sample].

    Science.gov (United States)

    Tereno, S; Guedeney, N; Dugravier, R; Greacen, T; Saïas, T; Tubach, F; Ulgen, S; Matos, I; Guédeney, A

    2017-04-01

    and Infant Protection System) is particularly generous and (b) the effect of this usual system might have been increased by the project intensive assessment protocol (6 visits during 28 months). Secondly, it is possible that the full effect of the intervention had not yet been detected because, when a child's attachment was assessed, only two thirds of the intervention visits had been performed (29 of 44 visits). A "sleeper effect" is still possible: we hope that a more clear result will be seen when children are assessed again, at 48 months, in our follow-up study (CAPEDP-A II). By clarifying the mechanisms involved in the development of a secure attachment, our study aims to contribute and refine the development of early preventive intervention strategies in high perinatal and psychosocial vulnerability contexts. Copyright © 2016 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  14. Evaluation of an automated single-channel sleep staging algorithm

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    Wang Y

    2015-09-01

    Full Text Available Ying Wang,1 Kenneth A Loparo,1,2 Monica R Kelly,3 Richard F Kaplan1 1General Sleep Corporation, Euclid, OH, 2Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, 3Department of Psychology, University of Arizona, Tucson, AZ, USA Background: We previously published the performance evaluation of an automated electroencephalography (EEG-based single-channel sleep–wake detection algorithm called Z-ALG used by the Zmachine® sleep monitoring system. The objective of this paper is to evaluate the performance of a new algorithm called Z-PLUS, which further differentiates sleep as detected by Z-ALG into Light Sleep, Deep Sleep, and Rapid Eye Movement (REM Sleep, against laboratory polysomnography (PSG using a consensus of expert visual scorers. Methods: Single night, in-lab PSG recordings from 99 subjects (52F/47M, 18–60 years, median age 32.7 years, including both normal sleepers and those reporting a variety of sleep complaints consistent with chronic insomnia, sleep apnea, and restless leg syndrome, as well as those taking selective serotonin reuptake inhibitor/serotonin–norepinephrine reuptake inhibitor antidepressant medications, previously evaluated using Z-ALG were re-examined using Z-PLUS. EEG data collected from electrodes placed at the differential-mastoids (A1–A2 were processed by Z-ALG to determine wake and sleep, then those epochs detected as sleep were further processed by Z-PLUS to differentiate into Light Sleep, Deep Sleep, and REM. EEG data were visually scored by multiple certified polysomnographic technologists according to the Rechtschaffen and Kales criterion, and then combined using a majority-voting rule to create a PSG Consensus score file for each of the 99 subjects. Z-PLUS output was compared to the PSG Consensus score files for both epoch-by-epoch (eg, sensitivity, specificity, and kappa and sleep stage-related statistics (eg, Latency to Deep Sleep, Latency to REM

  15. Efeito da idade e da posição radial na densidade básica e dimensões dos traqueídeos da madeira de Pinus taeda L. Effect of age and of the radial position in the basic density and dimensions of the tracheids of the wood of Pinus taeda L.

    Directory of Open Access Journals (Sweden)

    Rita de Cássia SOUSA

    2007-12-01

    Full Text Available O Pinus taeda L. é uma conífera exóticacultivada no Brasil. A madeira dessa espécie éutilizada na construção civil, dormentes, laminação,postes, resina, celulose e serraria. A questão básicaabordada no presente trabalho foi verificar se aidade da árvore influencia na densidade básica enas dimensões dos traqueídeos da madeira eanalisar as possíveis variações dessas propriedades,no sentido medula-casca, ao longo do raio dastoras de P. taeda. As propriedades estudadas foram:densidade básica (DB, comprimento, diâmetro eespessura da parede dos traqueídeos em função daidade em relação à posição radial. As propriedadesem estudo foram determinadas no Laboratório deAnatomia e Qualidade da Madeira do InstitutoFlorestal do Estado de São Paulo. Foram amostradascinco árvores no DAP (diâmetro à altura do peito,1,30 m médio em cada uma das idades de 9, 13e 20 anos de populações comerciais da região deSengés/PR. Os resultados indicaram que a idade daárvore influencia diretamente nessas propriedadesque são diferenciadas na posição radial da madeirade P. taeda. Também foi observado que ocorreuuma correlação positiva alta entre a densidadebásica e o comprimento dos traqueídeos.The Pinus taeda L. is an exotic conifercultivated in Brazil. The wood of that species isused in civil constructions, sleepers, veneer, posts,resin, cellulose and sawmill. The subject approachedin the present work was to verify if the age of thetree influences in the basic density and in thedimensions of the tracheids of the wood and toanalyze the possible variations of those properties,in the sense from pith to bark, along the ray of thelogs of P. taeda. The studied properties were: basicdensity (DB, length, diameter and thickness ofthe wall of the tracheids in function of the agerelated with the radial position. The properties instudy were established in the Laboratory of Anatomyand Quality of the Wood of the Forestry Institute ofSão Paulo

  16. Malaria transmission risk variations derived from different agricultural practices in an irrigated area of northern Tanzania.

    Science.gov (United States)

    Ijumba, J N; Mosha, F W; Lindsay, S W

    2002-03-01

    Malaria vector Anopheles and other mosquitoes (Diptera: Culicidae) were monitored for 12 months during 1994-95 in villages of Lower Moshi irrigation area (37 degrees 20' E, 3 degrees 21' S; approximately 700 m a.s.l.) south of Mount Kilimanjaro in northern Tanzania. Adult mosquito populations were sampled fortnightly by five methods: human bait collection indoors (18.00-06.00 hours) and outdoors (18.00-24.00 hours); from daytime resting-sites indoors and outdoors; by CDC light-traps over sleepers. Anopheles densities and rates of survival, anthropophily and malaria infection were compared between three villages representing different agro-ecosystems: irrigated sugarcane plantation; smallholder rice irrigation scheme, and savannah with subsistence crops. Respective study villages were Mvuleni (population 2200), Chekereni (population 3200) and Kisangasangeni (population approximately/= 1000), at least 7 km apart. Anopheles arabiensis Patton was found to be the principal malaria vector throughout the study area, with An. funestus Giles sensu lato of secondary importance in the sugarcane and savannah villages. Irrigated sugarcane cultivation resulted in water pooling, but this did not produce more vectors. Anopheles arabiensis densities averaged four-fold higher in the ricefield village, although their human blood-index was significantly less (48%) than in the sugarcane (68%) or savannah (66%) villages, despite similar proportions of humans and cows (ratio 1:1.1-1.4) as the main hosts at all sites. Parous rates, duration of the gonotrophic cycle and survival rates of An. arabiensis were similar in villages of all three agro-ecosystems. The potential risk of malaria, based on measurements of vectorial capacity of An. arabiensis and An.funestus combined, was four-fold higher in the ricefield village than in the sugarcane or savannah villages nearby. However, the more realistic estimate of malaria risk, based on entomological inoculation rates, indicated that exposure to

  17. Habitual sleep durations and subjective sleep quality predict white matter differences in the human brain

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    Sakh Khalsa

    2017-06-01

    Full Text Available Self-imposed short sleep durations are increasingly commonplace in society, and have considerable health and performance implications for individuals. Reduced sleep duration over multiple nights has similar behavioural effects to those observed following acute total sleep deprivation, suggesting that lack of sleep affects brain function cumulatively. A link between habitual sleep patterns and functional connectivity has previously been observed, and the effect of sleep duration on the brain's intrinsic functional architecture may provide a link between sleep status and cognition. However, it is currently not known whether differences in habitual sleep patterns across individuals are related to changes in the brain's white matter, which underlies structural connectivity. In the present study we use diffusion–weighted imaging and a group comparison application of tract based spatial statistics (TBSS to investigate changes to fractional anisotropy (FA and mean diffusivity (MD in relation to sleep duration and quality, hypothesising that white matter metrics would be positively associated with sleep duration and quality. Diffusion weighted imaging data was acquired from a final cohort of 33 (23–29 years, 10 female, mean 25.4 years participants. Sleep patterns were assessed for a 14 day period using wrist actigraphs and sleep diaries, and subjective sleep quality with the Pittsburgh Sleep Quality Index (PSQI. Median splits based on total sleep time and PSQI were used to create groups of shorter/longer and poorer/better sleepers, whose imaging data was compared using TBSS followed by post-hoc correlation analysis in regions identified as significantly different between the groups. There were significant positive correlations between sleep duration and FA in the left orbito-frontal region and the right superior corona radiata, and significant negative correlations between sleep duration and MD in right orbito-frontal white matter and the right

  18. Fe-bentonite. Experiments and modelling of the interactions of bentonites with iron

    Energy Technology Data Exchange (ETDEWEB)

    Herbert, Horst-Juergen; Xie, Mingliang [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany); Kasbohm, Joern; Lan, Nguyen T. [Greifswald Univ. (Germany); Hoang Thi Minh Thao [Hanoi Univ. of Science (Viet Nam)

    2011-11-15

    temperatures. The observed chemical and mineralogical changes of the smectites are well understood. Similar changes of the smectites occur in low as well as in high saline solutions with the sole difference that high ionic strength solutions lead to faster and stronger changes. Experimentally observed changes of swelling pressures and permeabilities are well understood and fit onto a coherent picture of mineral evolution. This picture is dependent on the Fe and Si activity in the bentonite-solution system. The observed mineralogical changes could be reproduced by geochemical modelling. The investigation of a large number of different bentonites within the framework of this study showed however that bentonites differ very much from each other and behave differently under similar boundary conditions. Favourable and less favourable bentonite compositions were identified. The results of this study have led to the definition of requirements for the bentonites to be used in the near field of a HLW repository. Summing up all the different findings of this study we conclude that the long term behaviour of the technical barrier bentonite in the near field of a HWA repository is controlled by the fate of Si in the system. Bentonites with mixed layers (%S < 100 %) can take up Si and form new montmorillonite layers. Such bentonites can inhibit or at least slow down the silica precipitation which is responsible for important permeability changes. An ideal bentonite would be a sleeper with %S = 70 %.

  19. Diferenças entre os Sexos no Aproveitamento Escolar, na Sintomatologia de Stress e na Qualidade do Sono em um Grupo de Adolescentes The Differences between the Gender in School Performance, in the Symptoms of Stress and Sleep Quality in a Group of Adolescents

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    Gema Galgani de Mesquita Duarte

    2014-03-01

    tools were used: 1 Pittsburgh Sleep Quality Index (PSQI; 2 Lipp’s Inventory of Stress Symptoms (LISS; 3 Students' grades and attendance records. Results: Among participants, 65.63% were females. The means of 0.64 for the female group (F and 0.60 for the male group (M were found for school learning. Regarding non-attendance, the means were 28.1 (F and 30.3 (M, with p=0,7440. Concerning stress symptoms, 65,71% (F and 29,09% (M were classified as stressed, while 34,29% (F and 70,91% (M showed no stress symptoms (p < 0.001. Females presented a poorer sleep quality: the means were 6,0 (F and 5,3 (M, with p = 0.27. The sleep classification revealed that 68,57% (F and 61,82% (M are poor sleepers. Conclusion: Females presented a better school learning, with higher grades, higher attendance, more stress symptoms, and poorer sleep quality.

  20. Inventory of contaminants in waste wood; Inventering av foeroreningar i returtrae

    Energy Technology Data Exchange (ETDEWEB)

    Jermer, Joeran; Ekvall, Annika; Tullin, Claes [Swedish National Testing and Research Inst., Boraas (Sweden)

    2001-03-01

    problems. Metal objects of zinc, brass and aluminium are considered to be particularly troublesome as they may plug primary air openings. PVC residues may cause considerably higher levels of chlorine in waste wood. Chemical analyses indicate that the distribution in levels of impurities varies a lot between deliveries of waste wood. Difficulties to take representative samples probably contribute to this. The knowledge of the contents of different types of waste wood (surface treated wood, preservative-treated, panels, furniture etc) in the waste wood flow is only fragmentary. Most certainly, surface treated (painted, stained etc) wood constitute the highest proportion. Preservative-treated wood, with the exception of railway sleepers and poles, is estimated to constitute approximately 5% of the waste wood flow in Sweden today and the next 25-30 years. The study has confirmed previous studies that waste wood contains a substantial proportion of fine fraction. 25-40% of the waste wood passed a sieve with a mesh size of 4 mm at screening trials. Chemical analyses indicated that the fine fraction will be the main contributor to contaminants of potassium, chlorine, sodium, zinc and lead. Further studies are suggested to focus on sorting, preparation, classification and quality assurance of waste wood.

  1. Comparisons of watershed sulfur budgets in southeast Canada and northeast US: New approaches and implications

    Science.gov (United States)

    Mitchell, M.J.; Lovett, G.; Bailey, S.; Beall, F.; Burns, D.; Buso, D.; Clair, T.A.; Courchesne, F.; Duchesne, L.; Eimers, C.; Fernandez, I.; Houle, D.; Jeffries, D.S.; Likens, G.E.; Moran, M.D.; Rogers, C.; Schwede, D.; Shanley, J.; Weathers, K.C.; Vet, R.

    2011-01-01

    Most of eastern North America receives elevated levels of atmospheric deposition of sulfur (S) that result from anthropogenic SO2 emissions from fossil fuel combustion. Atmospheric S deposition has acidified sensitive terrestrial and aquatic ecosystems in this region; however, deposition has been declining since the 1970s, resulting in some recovery in previously acidified aquatic ecosystems. Accurate watershed S mass balances help to evaluate the extent to which atmospheric S deposition is retained within ecosystems, and whether internal cycling sources and biogeochemical processes may be affecting the rate of recovery from decreasing S atmospheric loads. This study evaluated S mass balances for 15 sites with watersheds in southeastern Canada and northeastern US for the period 1985 to 2002. These 15 sites included nine in Canada (Turkey Lakes, ON; Harp Lake, ON; Plastic Lake, ON; Hermine, QC; Lake Laflamme, QC; Lake Clair, QC; Lake Tirasse, QC; Mersey, NS; Moosepit, NS) and six in the US (Arbutus Lake, NY; Biscuit Brook, NY; Sleepers River, VT; Hubbard Brook Experimental Forest, NH; Cone Pond, NH; Bear Brook Watershed, ME). Annual S wet deposition inputs were derived from measured bulk or wet-only deposition and stream export was obtained by combining drainage water fluxes with SO42- concentrations. Dry deposition has the greatest uncertainty of any of the mass flux calculations necessary to develop accurate watershed balances, and here we developed a new method to calculate this quantity. We utilized historical information from both the US National Emissions Inventory and the US (CASTNET) and the Canadian (CAPMoN) dry deposition networks to develop a formulation that predicted SO2 concentrations as a function of SO2 emissions, latitude and longitude. The SO2 concentrations were used to predict dry deposition using relationships between concentrations and deposition flux derived from the CASTNET or CAPMoN networks. For the year 2002, we compared the SO2

  2. 失眠相关的心理因素研究%Study on the Psychological Factors Related to Insomnia

    Institute of Scientific and Technical Information of China (English)

    Birling Yoann; 张锦花; 汪卫东

    2017-01-01

    目的:探讨失眠与睡眠的过度要求、对睡眠的控制、失眠的外归因以及睡眠依赖等心理因素的关系.方法:用汪氏失眠综合问卷(WIIQ)对150例失眠患者以及150例正常睡眠者进行横断性的问卷调查,用SPSS 22.0进行分析.结果:失眠症组心理因素总分及各分量表分相较于对照组更高(P<0.01).心理因素总分以及每个分量表的总分与WIIQ的失眠严重性指数之间有显著相关性(P<0.01),相关系数在0.571与0.746之间.在对照组中,曾经有过失眠的受试者的心理因素比从未失眠的受试者更多(P<0.01).临床试验患者中,治疗后比治疗前心理因素更少(P<0.01);心理因素总分与匹兹堡睡眠质量指数治疗前后差值之间有显著的相关性(P<0.01),相关系数为0.461.结论:失眠与睡眠的过度要求、对睡眠的控制、失眠的外归因以及睡眠依赖等不良的认知和行为相关,因素越多失眠越严重.失眠与相关的心理因素的因果关系可能是双向,即失眠带来心理因素,心理因素维持、加重失眠.通过心理治疗可以减少这些心理因素,进而缓解失眠.%Objective:To study the relation between insomnia and some psychological factors,excessive expectations about sleep,control of sleep,external attribution of insomnia and dependence about sleep.Methods:Wang Insomnia Integrated Questionnaire(WIIQ)was used in a survey of 150 primary insomnia patients and 150 matched normal sleepers,then the result was analyzed with SPSS 22.0.Results:The total score and subscales scores of psychological factors were higher in the insomnia group than the control group(P<0.01).The total score and subscales scores of psychological factors were all significantly correlated to WIIQ insomnia severity(P<0.01)with a correlation coefficient between 0.571 and 0.746.In the control group,the subject who had already experience insomnia had a higher score than the ones without insomnia experience(P<0.01).Insomnia

  3. Geologic setting and genesis of the Mule Canyon low-sulfidation epithermal gold-silver deposit, north-central Nevada

    Science.gov (United States)

    John, D.A.; Hofstra, A.H.; Fleck, R.J.; Brummer, J.E.; Saderholm, E.C.

    2003-01-01

    /or marcasite veins. Ore minerals consist mostly of electrum and Ag sulfide and selenide minerals, with minor to major amounts of pyrite, marcasite, and arsenopyrite, and local stibnite. Both types of ores have similar geochemical signatures, characterized by high Au, Ag, As, Sb, and Se contents, locally high Hg, Mo, Tl, and W contents, and low Cu, Pb, and Zn contents. Stable isotope data indicate that ore fluids consisted dominantly of meteoric water that evolved by deep circulation through Paleozoic sedimentary rocks at low water/rock ratios (about 1) and high temperatures (>200??C). Calculated isotopic compositions of ore fluids are ??18OH2O = -3 to -7 per mil, ??DH2O = -107 to -124 per mil, ??13CCO2 = 0 to -6 per mil, and ??34SH2S = -3 to +8 per mil. The ore fluids obtained much of their H2S and CO2 and probably scavenged ore metals and trace elements from the Paleozoic sedimentary rocks. Some H2S and CO2 may have been derived from degassing Miocene magmas. Mule Canyon formed at shallow depths, probably about 100 m below the paleosurface. Ore fluids were dilute, nearly neutral in pH, reduced, H2S-rich, and CO2-bearing. Peak temperatures in ore zones reached 230?? to 265??C at nearly lithostatic pressures when some crystalline quartz ?? adularia precipitated, but most ore formed at temperatures <200??C at near hydrostatic pressures and was accompanied by precipitation of opaline and chalcedonic silica ?? adularia ?? calcite and dolomite. Deposition of gold in As-rich overgrowths on pyrite and/or marcasite in disseminated ores occurred owing to decreasing H2S in the ore fluids resulting from sulfidation reactions. Later electrum and Ag selenide precipitation in open spaces occurred owing to boiling, loss of H2S to the vapor phase, and cooling. Mule Canyon is similar to most other low-sulfidation Au-Ag deposits associated with Miocene tholeiitic bimodal basalt-rhyolite magmatism in the Great Basin, such as Sleeper, Midas, and Buckhorn. Major differences at Mule Canyon are

  4. Liquidambar para produção de madeira no sul e sudeste do Brasil Sweetgum for wood production in the South and Southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Jarbas Yukio Shimizu

    2011-03-01

    equilíbrio. Além disso, esta espécie tem  a capacidade de regenerar vigorosamente a partir das  touças e das raízes adventícias.
    Sweetgum is a North and Central American tree species well known for the healing gum since the times of the Aztec civilization. In the southern United States, this is the most widely planted broadleaf species for wood  production. It grows well on a variety of site conditions, including on alluvial soil prone to flooding. As a result  of the wide natural distribution, it shows important variations in phenology and growth traits. The more  northern provenances tend to shut down growth processes much earlier and resume them later than the southern sources. These variations reflect directly on  the growth patterns among seed sources. Experiments  in several sites have demonstrated its potential value for wood production in small wood lots in the South and Southeastern Brazil. The most southern seed sources  (Central American have proved to be far more  productive than the North Americans; the fastest  growing provenances have shown productivity similar to fast growing eucalypts, in the order of 40 m3/ha.yr. The  ood has multiple use including pulp, railway sleepers, sawn timber, furniture and firewood. It is  especially valued for use in veneer and plywood  industries. However, it must be dealt with cautiously because of its highly invasive nature. In Brazil, it  produces large amounts of seed with great chances to  germinate and to rapidly take over the site. One key  factor for this success is the absence of foraging agents  uch as birds and rodents which coexist in its  natural range. Moreover, this species regenerates vigorously from stumps as well as from adventitious  roots.

  5. The Turkey oak high forests in the Molise region (central Italy. Analysis of past silvicultural system and current management choices.

    Directory of Open Access Journals (Sweden)

    Paolo Cantiani

    2010-12-01

    from Carpinus betulus stools clearcutting, was a further hindrance to the establishment of natural oak regeneration. In the fifties, the rate of forest management increased as a consequence of the coming up economic concern in sleeper production. The silvicultural shelterwood system was therefore codified. The system resulted to be more effective and adopted up to the present time. The traditional shelterwood system was based on a 90 yrs rotation length, three thinnings performed from the age of 25 up to 75, time of the seed cutting with a release of 90 trees per hectare. In the seventies, following the much more reduced and even null concern in wood production from oak high forests, practices into the same forests were suspended or postponed. At now, the renewed concern for fuelwood production, the only assortment marketable, as well as the increased attention paid to the multifunctional role of these forests, made again actual the problem of oak high forest management. The effectiveness of shelterwood system is the main outcome of the documental analysis performed. The study of the Carovilli’s chronosequence confirmed the close link between the current stand structures and the prescribed rules adopted in the past, in accordance with the management plans. The experimental trials in progress are now focused at defining an improvement of the shelterwood system practice as for the following issues: reduction of cutting areas; establishment of a more complex structural mosaic at neighbouring forest patches, setting up of a consistent release of seed trees i.e. number and dendrotypes to be selected at the purpose, with a special care to the crown cover to the forest floor, effective control of the understorey development due to the resprouting of Carpinus betulus stools, to enhance the establishment of oak natural regeneration. st1\\:*{behavior:url(#ieooui } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso

  6. Teasing out specific language impairment from an autism spectrum disorder.

    Science.gov (United States)

    Tierney, Cheryl D; Gupta, Vidya Bhushan; Angel, Alma Patricia Del; Augustyn, Marilyn

    2012-04-01

    Marcus is a handsome, sweet, 7½-year-old boy with a significant history of delayed development, specifically in speech and language skills, as well as difficulties with social interactions that have led other specialists to be concerned about a diagnosis of an autism spectrum disorder.He has been seen in our primary care practice since birth. He was born full-term after vaginal delivery weighing 6 pounds, 6 ounces. There were no pregnancy or delivery complications noted. Genetic testing revealed normal chromosomes, fragile X, and microarray testing. Marcus was a picky eater and good sleeper and had delays in toilet training.There is no family history of attention-deficit hyperactivity disorder (ADHD), autism, or substance abuse. Maternal grandmother and mother have a history of learning difficulties, and his father and a paternal uncle have a history of depression and anxiety. Marcus lives in a supportive environment with his mother, father, and sister.Marcus was noted to have significantly delayed language, stuttering, and immediate echolalia as a toddler. Gross and fine motor milestones were met on time, but he did not talk or follow directions until 4 to 5 years old. As a younger child, he would pretend to talk on the phone or mow the grass with a pretend lawn mower, but other household activities were not of interest to Marcus.Currently, he enjoys puzzles, reading, and board games. He likes to play with other children and can interact with familiar adults. Marcus is reported to initiate social interactions, although he has difficulty in understanding personal space. Imaginative play is preferred over other types. He seeks out adult attention and will bring objects over to an adult especially to share his perceived accomplishment. Marcus has difficulty in playing cooperatively with his sister.He is independent with activities of daily living. Marcus is noted to have auditory defensiveness including covering his ears to loud noises and becoming distressed

  7. Book review: The Sympathizer. A Vietnamese spy novel and the attempt to de-americanize our view on the war

    Directory of Open Access Journals (Sweden)

    Schmitz, Britta

    2018-03-01

    Full Text Available 1975, the Vietnam War has just ended, but the cold war and the clash of ideologies are still going on. This would of course be the perfect background for some run-of-the-mill thriller written by a white American for a Western audience. And without knowing anything further, we might first think that The Sympathizer, which was recently translated into German and marketed as a “thriller” and “spy novel”, would be just one of those. However, things and people are all too often not what they seem to be – an adage which has never been more true than in this story. Far more than simply a thriller, it is also a political novel, a satirical story, refugee literature and a critique of modern mass media, all interspersed with discursive passages and spiced with literary references and aphorisms. Furthermore, the author is not a white American. The Sympathizer is the debut novel of Vietnamese-American Viet Thanh Nguyen, which won him the Pulitzer Prize in 2016 along with a great many other awards. Nguyen was born in Vietnam and grew up in the USA from where he experienced both cultures and had insight to both perspectives on the Vietnam War. He is a Professor of English and American Studies and Ethnicity primarily focused on “Americanization”, how the American perspective continues to dominate film, literature and pop culture. His book is a critique of this prevailing view and includes the issues of acculturation and identity crisis of immigrants, along with the importance of loyalty and relationships (or the lack of those. The narrator and protagonist of the story is a man who has no name and is only referred to as “the captain” throughout the book. We encounter him fleeing Saigon, accompanying a general of the South Vietnamese army, we know already that he has a secret. In the very first lines he reveals that he is a sleeper agent and actually working for the Viet Cong and spying on the South Vietnamese military and the CIA. The captain