WorldWideScience

Sample records for sites insufficient information

  1. Superfund Site Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes a number of individual data sets related to site-specific information for Superfund, which is governed under the Comprehensive Environmental...

  2. Superfund Site Information - Site Sampling Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes Superfund site-specific sampling information including location of samples, types of samples, and analytical chemistry characteristics of...

  3. Current food chain information provides insufficient information for modern meat inspection of pigs.

    Science.gov (United States)

    Felin, Elina; Jukola, Elias; Raulo, Saara; Heinonen, Jaakko; Fredriksson-Ahomaa, Maria

    2016-05-01

    Meat inspection now incorporates a more risk-based approach for protecting human health against meat-borne biological hazards. Official post-mortem meat inspection of pigs has shifted to visual meat inspection. The official veterinarian decides on additional post-mortem inspection procedures, such as incisions and palpations. The decision is based on declarations in the food chain information (FCI), ante-mortem inspection and post-mortem inspection. However, a smooth slaughter and inspection process is essential. Therefore, one should be able to assess prior to slaughter which pigs are suitable for visual meat inspection only, and which need more profound inspection procedures. This study evaluates the usability of the FCI provided by pig producers and considered the possibility for risk ranking of incoming slaughter batches according to the previous meat inspection data and the current FCI. Eighty-five slaughter batches comprising 8954 fattening pigs were randomly selected at a slaughterhouse that receives animals from across Finland. The mortality rate, the FCI and the meat inspection results for each batch were obtained. The current FCI alone provided insufficient and inaccurate information for risk ranking purposes for meat inspection. The partial condemnation rate for a batch was best predicted by the partial condemnation rate calculated for all the pigs sent for slaughter from the same holding in the previous year (p<0.001) and by prior information on cough declared in the current FCI (p=0.02) statement. Training and information to producers are needed to make the FCI reporting procedures more accurate. Historical meat inspection data on pigs slaughtered from the same holdings and well-chosen symptoms/signs for reporting, should be included in the FCI to facilitate the allocation of pigs for visual inspection. The introduced simple scoring system can be easily used for additional information for directing batches to appropriate meat inspection procedures. To

  4. Brownfields Site Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset contains all Brownfield facility data. It includes all information necessary to track Brownfields grant recipients' environmental progress at Brownfield...

  5. Site specific information in site selection

    International Nuclear Information System (INIS)

    Aeikaes, T.; Hautojaervi, A.

    1998-01-01

    based on site specific information and evaluate the uncertainty is an important part of the discussion in the integrated work between site characterisation and safety assessment

  6. UST/LUST Site Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset contains all Underground Storage Tank (UST) site information. It includes details such as property location, acreage, identification and characterization,...

  7. Disposal Site Information Management System

    International Nuclear Information System (INIS)

    Larson, R.A.; Jouse, C.A.; Esparza, V.

    1986-01-01

    An information management system for low-level waste shipped for disposal has been developed for the Nuclear Regulatory Commission (NRC). The Disposal Site Information Management System (DSIMS) was developed to provide a user friendly computerized system, accessible through NRC on a nationwide network, for persons needing information to facilitate management decisions. This system has been developed on NOMAD VP/CSS, and the data obtained from the operators of commercial disposal sites are transferred to DSIMS semiannually. Capabilities are provided in DSIMS to allow the user to select and sort data for use in analysis and reporting low-level waste. The system also provides means for describing sources and quantities of low-level waste exceeding the limits of NRC 10 CFR Part 61 Class C. Information contained in DSIMS is intended to aid in future waste projections and economic analysis for new disposal sites

  8. Common site of subchondral insufficiency fractures of the femoral head based on three-dimensional magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Iwasaki, Kenyu; Yamamoto, Takuaki; Motomura, Goro; Karasuyama, Kazuyuki; Sonoda, Kazuhiko; Kubo, Yusuke; Iwamoto, Yukihide [Kyushu University, Department of Orthopaedic Surgery Graduate School of Medical Sciences, Higashi-ku, Fukuoka (Japan)

    2016-01-15

    The objective of this study was to investigate the common sites of subchondral insufficiency fractures of the femoral head (SIF) based on three-dimensional (3-D) reconstruction of MR images. In 33 hips of 31 consecutive patients diagnosed with SIF, 3-D reconstruction of the bone, fracture, and acetabular edge was performed using MR images. These 3-D images were used to measure the fractured areas and clarify the positional relationship between the fracture and degree of acetabular coverage. The fractured area in the anterior portion was significantly larger than in the posterior area. In 11 cases, the fractures contacted the acetabular edge and were distributed on the lateral portion. The indices of acetabular coverage (center-edge angle and acetabular head index) in these cases were less than the normal range. In the remaining 22 cases, the fractures were apart from the acetabular edge and distributed on the mediolateral centerline of the femoral head. The majority of these cases had normal acetabular coverage. The common site of SIF is the anterior portion. In addition, two types of SIF are proposed: (1) Lateral type: the contact stress between the acetabular edge and lateral portion of the femoral head causes SIF based on the insufficient acetabular coverage, and (2) Central type: the contact stress between the acetabular surface and the mediolateral center of the femoral head causes SIF independent from the insufficiency of acetabular coverage. These findings may be useful for considering the treatment and prevention of SIF. (orig.)

  9. Risk assessment during operating self-propelled lifting jib cranes in conditions of insufficient information

    Directory of Open Access Journals (Sweden)

    Lagerev A.V.

    2017-06-01

    Full Text Available Presents the results of statistical analyses identified by the expert diagnostics of defects of the self-propelled lifting jib cranes, spent a normative term of exploitation. The greatest number of defects associated with the destruction and dete-rioration of structural elements, the occurrence of fatigue cracks and a violation of the conditions of operation of the equipment. The greatest number of defects occurs in the hydraulic system of cranes, the rope-block system, and rarely in steel structures. To conduct risk analysis of self-propelled jib cranes in case of insufficient information, proposed the method of expert estimations. It allows to assess the impact of potential defects on self-propelled jib cranes on the value of the economic damage of the crane and moving cargo and the value of the traumatic exposure on men. The proposed list of possible defects self-propelled lifting jib cranes and a checklist of questions about the degree of influence of these defects. Proposed calculated dependences to the approximate calculation of the magnitude of technical risk in the opera-tion of self-propelled jib cranes. The results of statistical analysis of expert estimations for each possible defect and per-formed their ranking in terms of impact on the magnitude of the economic damage of the crane and moving loads, the value of the traumatic exposure. Was calculated the value of technical risk for the surveyed taps.

  10. Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses

    DEFF Research Database (Denmark)

    Brok, J.; Thorlund, K.; Gluud, C.

    2008-01-01

    in 80% (insufficient information size). TSA(15%) and TSA(LBHIS) found that 95% and 91% had absence of evidence. The remaining nonsignificant meta-analyses had evidence of lack of effect. CONCLUSION: TSA reveals insufficient information size and potentially false positive results in many meta......OBJECTIVES: To evaluate meta-analyses with trial sequential analysis (TSA). TSA adjusts for random error risk and provides the required number of participants (information size) in a meta-analysis. Meta-analyses not reaching information size are analyzed with trial sequential monitoring boundaries...... analogous to interim monitoring boundaries in a single trial. STUDY DESIGN AND SETTING: We applied TSA on meta-analyses performed in Cochrane Neonatal reviews. We calculated information sizes and monitoring boundaries with three different anticipated intervention effects of 30% relative risk reduction (TSA...

  11. Online Particle Physics Information - Education Sites

    Science.gov (United States)

    SLAC Online Particle Physics Information Particle Data Group Particle Physics Education Sites General Sites Background Knowledge Physics Lessons & Activities Astronomy Lessons & Activities Ask -A-Scientist Experiments, Demos and Fun Physics History & Diversity Art in Physics General Sites

  12. Aortic insufficiency

    Science.gov (United States)

    ... page, please enable JavaScript. Aortic insufficiency is a heart valve disease in which the aortic valve does not close ... aortic insufficiency Images Aortic insufficiency References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  13. Robust Target Tracking with Multi-Static Sensors under Insufficient TDOA Information.

    Science.gov (United States)

    Shin, Hyunhak; Ku, Bonhwa; Nelson, Jill K; Ko, Hanseok

    2018-05-08

    This paper focuses on underwater target tracking based on a multi-static sonar network composed of passive sonobuoys and an active ping. In the multi-static sonar network, the location of the target can be estimated using TDOA (Time Difference of Arrival) measurements. However, since the sensor network may obtain insufficient and inaccurate TDOA measurements due to ambient noise and other harsh underwater conditions, target tracking performance can be significantly degraded. We propose a robust target tracking algorithm designed to operate in such a scenario. First, track management with track splitting is applied to reduce performance degradation caused by insufficient measurements. Second, a target location is estimated by a fusion of multiple TDOA measurements using a Gaussian Mixture Model (GMM). In addition, the target trajectory is refined by conducting a stack-based data association method based on multiple-frames measurements in order to more accurately estimate target trajectory. The effectiveness of the proposed method is verified through simulations.

  14. Risks of insufficient information communication during the post-accident period of the Chernobyl accident

    International Nuclear Information System (INIS)

    Joukovskaia, Olga V.; Rolevich, Igor V.

    2000-01-01

    The modified psychological climate and increased social-psychological pressure in the population, affected as a result of the Chernobyl accident, emerged partially because of insufficient information provided to the population with respect to the radiation and ecological conditions. Such situation resulted in development of chronic psychological stress in the majority of the population residing on the affected areas. The post-accidental stress, which appeared in many people, is characterized by its extraordinary stability. Up to 74% of the affected population were subjected to stress. In 1986 the depressing condition of anxiety was observed in 50% of those examined. By 1998 this number increased up to 76%. Aggravation of health condition still remains in the center of anxiety reasons for the majority of those examined, when in the areas contaminated greater the number of those anxious is much higher than in others. Besides, the urban population is more concerned in unsatisfactory solution of the problem of liquidation of the Chernobyl accident consequences, than village inhabitants (88,5 and 79,70/o accordingly). Noteworthy, that 43% of the urban population and only 25,20/6 of the village settlers is concerned in small efficiency of rehabilitation activities on the radioactive contaminated territories. Respondents-women 86,1%) are more anxious than men 84,2%). Besides, almost three quarters of the respondents 74,5%) for last three years became more anxious for their future and future of their children, which leads to greater worries. At the same time it is necessary to take into account, that 7 of the respondents expressed apathy and indifference to everything, and at 75% have the feeling of hopelessness. Another negative tendency exposed in the population, affected by the Chernobyl accident is the reduction of trust to the authorities and governmental bodies, reduction of satisfaction by the activity of local authorities. Only 60,6% of the interrogated

  15. Strategic plan for Hanford site information management

    International Nuclear Information System (INIS)

    1994-09-01

    The Hanford Site missions are to clean up the Site, to provide scientific knowledge and technology to meet global needs, and to partner in the economic diversification of the region. To achieve these long-term missions and increase confidence in the quality of the Site's decision making process, a dramatically different information management culture is required, consistent with US Department of Energy (DOE) mandates on increased safety, productivity, and openness at its sites. This plan presents a vision and six strategies that will move the Site toward an information management culture that will support the Site missions and address the mandates of DOE

  16. Protecting Personal Information on Social Networking Sites

    Science.gov (United States)

    Gallant, David T.

    2011-01-01

    Almost everyone uses social networking sites like Facebook, MySpace, and LinkedIn. Since Facebook is the most popular site in the history of the Internet, this article will focus on how one can protect his/her personal information and how that extends to protecting the private information of others.

  17. Information Architecture for Bilingual Web Sites.

    Science.gov (United States)

    Cunliffe, Daniel; Jones, Helen; Jarvis, Melanie; Egan, Kevin; Huws, Rhian; Munro, Sian

    2002-01-01

    Discusses creating an information architecture for a bilingual Web site and reports work in progress on the development of a content-based bilingual Web site to facilitate shared resources between speech and language therapists. Considers a structural analysis of existing bilingual Web designs and explains a card-sorting activity conducted with…

  18. Imaging of insufficiency fractures

    Energy Technology Data Exchange (ETDEWEB)

    Krestan, Christian [Department of Radiology, Medical University of Vienna, Vienna General Hospital, Waehringerstr. 18-20, 1090 Vienna (Austria)], E-mail: christian.krestan@meduniwien.ac.at; Hojreh, Azadeh [Department of Radiology, Medical University of Vienna, Vienna General Hospital, Waehringerstr. 18-20, 1090 Vienna (Austria)

    2009-09-15

    This review focuses on the occurrence, imaging and differential diagnosis of insufficiency fractures. Prevalence, the most common sites of insufficiency fractures and their clinical implications are discussed. Insufficiency fractures occur with normal stress exerted on weakened bone. Postmenopausal osteoporosis is the most common cause of insufficiency fractures. Other conditions which affect bone turnover include osteomalacia, hyperparathyroidism, chronic renal failure and high-dose glucocorticoid therapy. It is a challenge for the radiologist to detect and diagnose insufficiency fractures, and to differentiate them from other bone lesions. Radiographs are still the most widely used imaging method for identification of insufficiency fractures, but sensitivity is limited, depending on the location of the fractures. Magnetic resonance imaging (MRI) is a very sensitive tool to visualize bone marrow abnormalities associated with insufficiency fractures. Thin section, multi-detector computed tomography (MDCT) depicts subtle fracture lines allowing direct visualization of cortical and trabecular bone. Bone scintigraphy still plays a role in detecting fractures, with good sensitivity but limited specificity. The most important differential diagnosis is underlying malignant disease leading to pathologic fractures. Bone densitometry and clinical history may also be helpful in confirming the diagnosis of insufficiency fractures.

  19. Searching your site`s management information systems

    Energy Technology Data Exchange (ETDEWEB)

    Marquez, W.; Rollin, C. [S.M. Stoller Corp., Boulder, CO (United States)

    1994-12-31

    The Department of Energy`s guidelines for the Baseline Environmental Management Report (BEMR) encourage the use of existing data when compiling information. Specific systems mentioned include the Progress Tracking System, the Mixed-Waste Inventory Report, the Waste Management Information System, DOE 4700.1-related systems, Programmatic Environmental Impact Statement (PEIS) data, and existing Work Breakdown Structures. In addition to these DOE-Headquarters tracking and reporting systems, there are a number of site systems that will be relied upon to produce the BEMR, including: (1) site management control and cost tracking systems; (2) commitment/issues tracking systems; (3) program-specific internal tracking systems; (4) Site material/equipment inventory systems. New requirements have often prompted the creation of new, customized tracking systems. This is a very time and money consuming process. As the BEMR Management Plan emphasizes, an effort should be made to use the information in existing tracking systems. Because of the wealth of information currently available from in-place systems, development of a new tracking system should be a last resort.

  20. Searching your site's management information systems

    International Nuclear Information System (INIS)

    Marquez, W.; Rollin, C.

    1994-01-01

    The Department of Energy's guidelines for the Baseline Environmental Management Report (BEMR) encourage the use of existing data when compiling information. Specific systems mentioned include the Progress Tracking System, the Mixed-Waste Inventory Report, the Waste Management Information System, DOE 4700.1-related systems, Programmatic Environmental Impact Statement (PEIS) data, and existing Work Breakdown Structures. In addition to these DOE-Headquarters tracking and reporting systems, there are a number of site systems that will be relied upon to produce the BEMR, including: (1) site management control and cost tracking systems; (2) commitment/issues tracking systems; (3) program-specific internal tracking systems; (4) Site material/equipment inventory systems. New requirements have often prompted the creation of new, customized tracking systems. This is a very time and money consuming process. As the BEMR Management Plan emphasizes, an effort should be made to use the information in existing tracking systems. Because of the wealth of information currently available from in-place systems, development of a new tracking system should be a last resort

  1. Hanford Site Waste Storage Tank Information Notebook

    International Nuclear Information System (INIS)

    Husa, E.I.; Raymond, R.E.; Welty, R.K.; Griffith, S.M.; Hanlon, B.M.; Rios, R.R.; Vermeulen, N.J.

    1993-07-01

    This report provides summary data on the radioactive waste stored in underground tanks in the 200 East and West Areas at the Hanford Site. The summary data covers each of the existing 161 Series 100 underground waste storage tanks (500,000 gallons and larger). It also contains information on the design and construction of these tanks. The information in this report is derived from existing reports that document the status of the tanks and their materials. This report also contains interior, surface photographs of each of the 54 Watch List tanks, which are those tanks identified as Priority I Hanford Site Tank Farm Safety Issues in accordance with Public Law 101-510, Section 3137*

  2. Adrenal Insufficiency

    Science.gov (United States)

    ... two kinds of AI: • Primary AI, also called Addison’s disease. In this rare condition, the adrenal glands do ... org (search for adrenal) • Information about AI and Addison’s disease from the National Institutes of Health: www. endocrine. ...

  3. Communicate: Journal of Library and Information Science: Site Map

    African Journals Online (AJOL)

    Communicate: Journal of Library and Information Science: Site Map. Journal Home > About the Journal > Communicate: Journal of Library and Information Science: Site Map. Log in or Register to get access to full text downloads.

  4. Lagos Journal of Library and Information Science: Site Map

    African Journals Online (AJOL)

    Lagos Journal of Library and Information Science: Site Map. Journal Home > About the Journal > Lagos Journal of Library and Information Science: Site Map. Log in or Register to get access to full text downloads.

  5. Information System Security: Army Web Site Administration, Policies, and Practices

    National Research Council Canada - National Science Library

    2002-01-01

    .... The Policy requires heads of DoD Components to establish a process to identify appropriate information for posting to Web sites and to review all information placed on publicly accessible Web sites...

  6. Screening for renal insufficiency following ESUR (European Society of Urogenital Radiology) guidelines with on-site creatinine measurements in an outpatient setting

    International Nuclear Information System (INIS)

    Ledermann, H.P.; Mengiardi, B.; Schmid, A.; Froehlich, J.M.

    2010-01-01

    To report the results and implications for workflow following introduction of ESUR guidelines to screen for potential renal insufficiency (RI) in private practice with on-site creatinine measurements. A total of 1,766 consecutive outpatients scheduled for contrast-enhanced CT (CECT) completed the ESUR questionnaire enquiring about kidney disease, renal surgery, proteinuria, diabetes mellitus, hypertension, gout or use of nephrotoxic drugs. Patients with positive risk factors underwent on-site creatinine measurement and calculation of estimated glomerular filtration rate (eGFR). Attending radiologists adapted subsequent imaging depending on renal function and presence of risk factors. One or more ESUR risk factors were present in 796 (45.1%) patients, including hypertension (37.7%), nephrotoxic medication (21.3%), diabetes mellitus (8.0%), proteinuria (3.9%), renal disease (4.1%), gout (3.1%) and renal surgery (2.6%). Pre-procedural creatinine measurements revealed severe RI (eGFR -1 1.73 m -2 ) in 10 (1.3%) and moderate RI (eGFR 30-59 ml min -1 1.73 m -2 ) in 106 (13.8%). Imaging work-up was adapted in 132 (16.6%) as follows: reduction of contrast material dose (n = 85), CT without contrast (n = 40), changeover to MRI (n = 3) or scintigraphy (n = 4). Screening for RI following ESUR guidelines requires creatinine measurements in nearly half of outpatients scheduled for CECT and reveals moderate to severe renal impairment in 6.6%. (orig.)

  7. EPA Geospatial Data Download: Facility and Site Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — Contains information about facilities or sites subject to environmental regulation, including key facility information along with associated environmental interests...

  8. Screening for renal insufficiency following ESUR (European Society of Urogenital Radiology) guidelines with on-site creatinine measurements in an outpatient setting

    Energy Technology Data Exchange (ETDEWEB)

    Ledermann, H.P.; Mengiardi, B.; Schmid, A. [IMAMED Radiologie Nordwest, Basel (Switzerland); Froehlich, J.M. [Guerbet AG, Medical Affairs, Zurich (Switzerland); University of Bern, Radiology Department, Bern (Switzerland)

    2010-08-15

    To report the results and implications for workflow following introduction of ESUR guidelines to screen for potential renal insufficiency (RI) in private practice with on-site creatinine measurements. A total of 1,766 consecutive outpatients scheduled for contrast-enhanced CT (CECT) completed the ESUR questionnaire enquiring about kidney disease, renal surgery, proteinuria, diabetes mellitus, hypertension, gout or use of nephrotoxic drugs. Patients with positive risk factors underwent on-site creatinine measurement and calculation of estimated glomerular filtration rate (eGFR). Attending radiologists adapted subsequent imaging depending on renal function and presence of risk factors. One or more ESUR risk factors were present in 796 (45.1%) patients, including hypertension (37.7%), nephrotoxic medication (21.3%), diabetes mellitus (8.0%), proteinuria (3.9%), renal disease (4.1%), gout (3.1%) and renal surgery (2.6%). Pre-procedural creatinine measurements revealed severe RI (eGFR < 30 ml min{sup -1} 1.73 m{sup -2}) in 10 (1.3%) and moderate RI (eGFR 30-59 ml min{sup -1} 1.73 m{sup -2}) in 106 (13.8%). Imaging work-up was adapted in 132 (16.6%) as follows: reduction of contrast material dose (n = 85), CT without contrast (n = 40), changeover to MRI (n = 3) or scintigraphy (n = 4). Screening for RI following ESUR guidelines requires creatinine measurements in nearly half of outpatients scheduled for CECT and reveals moderate to severe renal impairment in 6.6%. (orig.)

  9. Site-Based Management. ERS Information Aid.

    Science.gov (United States)

    Educational Research Service, Arlington, VA.

    Although many school districts eagerly embrace site-based management to resolve some fundamental problems facing education, it is wise to consider what effects this decentralization can realistically have. Since procedures vary from school to school, the literature cannot yet furnish guidelines for ensuring a particular program's success. To help…

  10. Determining the cross-channel effects of informational web sites

    NARCIS (Netherlands)

    Teerling, Marije Leonie

    2007-01-01

    This dissertation investigates the effects of an informational Web site on offline behavior, specifically with regard to customer buying behavior in a “traditional” store. This chapter serves to introduce the literature on informational Web sites (§1.2) and the multichannel environment (§1.3). It

  11. Information site for parents of young children

    OpenAIRE

    Heggedal, Eivind

    2005-01-01

    For parents of small children and lay people it can be difficult to navigate specialist literature when trying to access paediatric problems on their own. Although information targeted at this group already exists, both on the Internet and in different brochures, pamphlets and books, it is of varying quality and is not always easily accessible. With this in mind, there is a need to collect and simplify the literature on this subject, and make it available to lay people and parents of smal...

  12. Site report for the office information management conference

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, G.P.

    1989-12-31

    The charter of the End User Services Section is to plan and support office information systems for Savannah River Site organizations and be the first point of contact for users of Information Resource Management Department computer services. This includes personal workstation procurement, electronic mail, computer aided design, operations analysis, and access to information systems both on and off site. The mission also includes the training and support of personnel in the effective use of the new and existing systems.

  13. Site report for the office information management conference

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, G.P.

    1989-01-01

    The charter of the End User Services Section is to plan and support office information systems for Savannah River Site organizations and be the first point of contact for users of Information Resource Management Department computer services. This includes personal workstation procurement, electronic mail, computer aided design, operations analysis, and access to information systems both on and off site. The mission also includes the training and support of personnel in the effective use of the new and existing systems.

  14. Factors Enabling Information Propagation in a Social Network Site

    DEFF Research Database (Denmark)

    Magnani, Matteo; Montesi, Danilo; Rossi, Luca

    2013-01-01

    A relevant feature of Social Network Sites is their ability to propagate units of information and create large distributed conversations. This phenomenon is particularly relevant because of the speed of information propagation, which is known to be much faster than within traditional media......, and because of the very large amount of people that can potentially be exposed to information items. While many general formal models of network propagation have been developed in different research fields, in this chapter we present the result of an empirical study on a Large Social Database (LSD) aimed...... at measuring specific socio-technical factors enabling information spreading in Social Network Sites....

  15. Report: EPA’s Information Systems and Data Are at Risk Due to Insufficient Training of Personnel With Significant Information Security Responsibilities

    Science.gov (United States)

    Report #14-P-0142, March 21, 2014. The EPA places its information systems and data at risk due to an organizational structure that has not specified required duties and responsibilities to ensure personnel are trained on key information security roles.

  16. Strategic plan for Hanford Site Environmental Restoration Information Management

    International Nuclear Information System (INIS)

    Cowley, P.J.; Beck, J.E.; Gephart, R.E.

    1994-06-01

    This strategic plan addresses information management for the Environmental Restoration (ER) Program at the Hanford Site. This Program leads the cleanup of the Hanford Site's soil, groundwater, buried waste, and the decontamination and decommissioning of facilities. The vision that drives this strategic plan is to ensure that quality information is available to the people who need it, when they need it, at a convenient location, in a usable form, and at an acceptable cost. Although investments are being made in managing the vast amounts of information, which include data, records and documents associated with the Hanford Site's production history and new cleanup mission, it is widely recognized that efforts to date have not accomplished the vision. Effective information management involves more than the compilation of massive amounts of electronic and non-electronic information. It also involves integrating information management into business processes that support user's needs and decisionmaking. Only then can information management complement and enable environmental restoration priorities and practices, help identify environmental restoration requirements, and enable communication within the Environmental Restoration Program and between the Program and its stakeholders. Successfully accomplishing the Hanford Site mission requires an integrated approach to information management that crosses organizational boundaries, streamlines existing systems, and builds new systems that support the needs of the future. This plan outlines that approach

  17. NASA space geodesy program: Catalogue of site information

    Science.gov (United States)

    Bryant, M. A.; Noll, C. E.

    1993-01-01

    This is the first edition of the NASA Space Geodesy Program: Catalogue of Site Information. This catalogue supersedes all previous versions of the Crustal Dynamics Project: Catalogue of Site Information, last published in May 1989. This document is prepared under the direction of the Space Geodesy and Altimetry Projects Office (SGAPO), Code 920.1, Goddard Space Flight Center. SGAPO has assumed the responsibilities of the Crustal Dynamics Project, which officially ended December 31, 1991. The catalog contains information on all NASA supported sites as well as sites from cooperating international partners. This catalog is designed to provde descriptions and occupation histories of high-accuracy geodetic measuring sites employing space-related techniques. The emphasis of the catalog has been in the past, and continues to be with this edition, station information for facilities and remote locations utilizing the Satellite Laser Ranging (SLR), Lunar Laser Ranging (LLR), and Very Long Baseline Interferometry (VLBI) techniques. With the proliferation of high-quality Global Positioning System (GPS) receivers and Doppler Orbitography and Radiopositioning Integrated by Satellite (DORIS) transponders, many co-located at established SLR and VLBI observatories, the requirement for accurate station and localized survey information for an ever broadening base of scientists and engineers has been recognized. It is our objective to provide accurate station information to scientific groups interested in these facilities.

  18. Recurrent Tricuspid Insufficiency

    Science.gov (United States)

    Kara, Ibrahim; Koksal, Cengiz; Cakalagaoglu, Canturk; Sahin, Muslum; Yanartas, Mehmet; Ay, Yasin; Demir, Serdar

    2013-01-01

    This study compares the medium-term results of De Vega, modified De Vega, and ring annuloplasty techniques for the correction of tricuspid insufficiency and investigates the risk factors for recurrent grades 3 and 4 tricuspid insufficiency after repair. In our clinic, 93 patients with functional tricuspid insufficiency underwent surgical tricuspid repair from May 2007 through October 2010. The study was retrospective, and all the data pertaining to the patients were retrieved from hospital records. Functional capacity, recurrent tricuspid insufficiency, and risk factors aggravating the insufficiency were analyzed for each patient. In the medium term (25.4 ± 10.3 mo), the rates of grades 3 and 4 tricuspid insufficiency in the De Vega, modified De Vega, and ring annuloplasty groups were 31%, 23.1%, and 6.1%, respectively. Logistic regression analysis revealed that chronic obstructive pulmonary disease, left ventricular dysfunction (ejection fraction, tricuspid insufficiency. Medium-term survival was 90.6% for the De Vega group, 96.3% for the modified De Vega group, and 97.1% for the ring annuloplasty group. Ring annuloplasty provided the best relief from recurrent tricuspid insufficiency when compared with DeVega annuloplasty. Modified De Vega annuloplasty might be a suitable alternative to ring annuloplasty when rings are not available. PMID:23466680

  19. Laboratory information management system at the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    Leggett, W.; Barth, D.; Ibsen, T.; Newman, B.

    1994-03-01

    In January of 1994 an important new technology was brought on line to help in the monumental waste management and environmental restoration work at the Hanford Site. Cleanup at the Hanford Site depends on analytical chemistry information to identify contaminates, design and monitor cleanup processes, assure worker safety, evaluate progress, and prove completion. The new technology, a laboratory information management system (LIMS) called ``LABCORE,`` provides the latest systems to organize and communicate the analytical tasks: track work and samples; collect and process data, prepare reports, and store data in readily accessible electronic form.

  20. Laboratory information management system at the Hanford Site

    International Nuclear Information System (INIS)

    Leggett, W.; Barth, D.; Ibsen, T.; Newman, B.

    1994-03-01

    In January of 1994 an important new technology was brought on line to help in the monumental waste management and environmental restoration work at the Hanford Site. Cleanup at the Hanford Site depends on analytical chemistry information to identify contaminates, design and monitor cleanup processes, assure worker safety, evaluate progress, and prove completion. The new technology, a laboratory information management system (LIMS) called ''LABCORE,'' provides the latest systems to organize and communicate the analytical tasks: track work and samples; collect and process data, prepare reports, and store data in readily accessible electronic form

  1. When is there sufficient information from the Site Investigations?

    International Nuclear Information System (INIS)

    Andersson, Johan; Munier, Raymond; Stroem, Anders; Soederbaeck, Bjoern; Almen, Karl-Erik; Olsson, Lars

    2004-04-01

    SKB has started site investigations for a deep repository for spent nuclear fuel at two different sites in Sweden. The investigations should provide necessary information for a licence application aimed at starting underground exploration. The investigations and analyses of them are supposed to provide the broad knowledge base that is required to achieve the overall goals of the site investigation phase. The knowledge will be utilized to evaluate the suitability of investigated sites for the deep repository and must be comprehensive enough to: Show whether the selected site satisfies requirements on safety and technical aspects. Serve as a basis for adaptation of the deep repository to the characteristics of the site with an acceptable impact on society and the environment. Permit comparisons with other investigated sites. Furthermore, the investigations are discontinued when the reliability of the site description has reached such a level that the body of data for safety assessment and design is sufficient, or until the body of data shows that the rock does not satisfy the requirements. These objectives are valid, but do not provide sufficient and concrete guidance. For this reason SKB has conducted this project which should acquire concrete guidance on how to judge when the surface based Site Investigation Phase does not need to continue. After a general assessment of the problem, the following specific objectives of the current work were identified: Demonstrate concretely how the assessed uncertainties in a Site Description based on a specific level of investigations, together with expected feedback from Safety Assessment and Engineering, can be used to decide whether the site investigations are sufficient - or need to continue. This demonstration will be based on a practical application of relevant aspects of decision analysis tools. Highlight and make concrete the type of feedback to be expected from Safety Assessment and Engineering and show how this feedback

  2. Low-Level Radioactive Waste siting simulation information package

    International Nuclear Information System (INIS)

    1985-12-01

    The Department of Energy's National Low-Level Radioactive Waste Management Program has developed a simulation exercise designed to facilitate the process of siting and licensing disposal facilities for low-level radioactive waste. The siting simulation can be conducted at a workshop or conference, can involve 14-70 participants (or more), and requires approximately eight hours to complete. The exercise is available for use by states, regional compacts, or other organizations for use as part of the planning process for low-level waste disposal facilities. This information package describes the development, content, and use of the Low-Level Radioactive Waste Siting Simulation. Information is provided on how to organize a workshop for conducting the simulation. 1 ref., 1 fig

  3. Second Information Technology in Education Study: SITES 2006 Technical Report

    Science.gov (United States)

    Carstens, Ralph, Ed.; Pelgrum, Willem J., Ed.

    2009-01-01

    The International Association for the Evaluation of Educational Achievement (IEA) has been conducting comparative studies for 50 years. SITES 2006 is the fifth wave of surveys related to information and communication technology (ICT), a wave that IEA started with its Computers in Education Study (two studies with data collection in 1989 and 1992),…

  4. Pubic insufficiency fracture: MRI findings

    International Nuclear Information System (INIS)

    Min, Tae Kyu; Lee, Yeon Soo; Park, Jeong Mi; Kim, Jee Young; Chung, Hong Jun; Lee, Eun Hee; Lee, Eun Ja; Kang, So Won; Han Tae Il

    2000-01-01

    To evaluate the characteristic MRI findings of pubic insufficiency fracture. In nine cases of pubic insufficiency fracture, the findings of plain radiography (n=9), MRI (n=9), and bone scintigraphy (n=8) were reviewed. We retrospectively analyzed, with regard to fracture site, the destructive pattern revealed by plain radiography, and uptake by other pelvic bones, as demonstrated by RI bone scanning. The MR findings evaluated were the fracture gap and its signal intensity, the site and signal intensity of the soft tissue mass, and other pelvic bone fractures. Plain radiography revealed osteolysis and sclerosis of pubic bone in eight of nine cases (89%), and parasymphyseal fractures in seven (78%). RI indicated uptake by the sacrum in six cases (66%), and by the ilium in three (33%). MR findings of fracture gap (seven cases, 78%) were hypo to isointensity on T1WI, hyper intensity on T2WI and the absence of contrast enhancement. Soft tissue masses were found in seven cases (78%); in four of these the location was parasymphyseal, and in three, surrounding muscle was involved. Hypo to isointensity was revealed by T1WI, hyperintensity by T2WI, and there was peripheral enhancement. Other associated pelvic bone fractures involved the sacrum in seven cases and the ilium in four. The characteristic MR findings of pubic insufficiency fracture were parasymphyseal location, fracture gap, peripherally enhanced soft tissue mass formation, and fractures of other pelvic bones, namely the sacrum and ilium

  5. Hanford Site Guidelines for Preparation and Presentation of Geologic Information

    Energy Technology Data Exchange (ETDEWEB)

    Lanigan, David C.; Last, George V.; Bjornstad, Bruce N.; Thorne, Paul D.; Webber, William D.

    2010-04-30

    A complex geology lies beneath the Hanford Site of southeastern Washington State. Within this geology is a challenging large-scale environmental cleanup project. Geologic and contaminant transport information generated by several U.S. Department of Energy contractors must be documented in geologic graphics clearly, consistently, and accurately. These graphics must then be disseminated in formats readily acceptable by general graphics and document producing software applications. The guidelines presented in this document are intended to facilitate consistent, defensible, geologic graphics and digital data/graphics sharing among the various Hanford Site agencies and contractors.

  6. Comprehensive Calibration and Validation Site for Information Remote Sensing

    Science.gov (United States)

    Li, C. R.; Tang, L. L.; Ma, L. L.; Zhou, Y. S.; Gao, C. X.; Wang, N.; Li, X. H.; Wang, X. H.; Zhu, X. H.

    2015-04-01

    As a naturally part of information technology, Remote Sensing (RS) is strongly required to provide very precise and accurate information product to serve industry, academy and the public at this information economic era. To meet the needs of high quality RS product, building a fully functional and advanced calibration system, including measuring instruments, measuring approaches and target site become extremely important. Supported by MOST of China via national plan, great progress has been made to construct a comprehensive calibration and validation (Cal&Val) site, which integrates most functions of RS sensor aviation testing, EO satellite on-orbit caration and performance assessment and RS product validation at this site located in Baotou, 600km west of Beijing. The site is equipped with various artificial standard targets, including portable and permanent targets, which supports for long-term calibration and validation. A number of fine-designed ground measuring instruments and airborne standard sensors are developed for realizing high-accuracy stepwise validation, an approach in avoiding or reducing uncertainties caused from nonsynchronized measurement. As part of contribution to worldwide Cal&Val study coordinated by CEOS-WGCV, Baotou site is offering its support to Radiometric Calibration Network of Automated Instruments (RadCalNet), with an aim of providing demonstrated global standard automated radiometric calibration service in cooperation with ESA, NASA, CNES and NPL. Furthermore, several Cal&Val campaigns have been performed during the past years to calibrate and validate the spaceborne/airborne optical and SAR sensors, and the results of some typical demonstration are discussed in this study.

  7. Technical advisory on SSC site criteria and catalog of site information needs

    Energy Technology Data Exchange (ETDEWEB)

    1985-06-15

    The Superconducting Super Collider, or SSC, is a proposed scientific instrument of the study of the fundamental nature of matter. In the SSC two 20-TeV beams of protons will be accelerated and counter circulate on an approximately circular path. The protons will be made to collide at six locations where detectors can be placed to count and measure the products of the collisions. These collisions, twenty times more energetic than in any existing facility, will enable scientists to probe deeper into the heart of matter in the quest for a deeper understanding of the universal forces of nature. The goal of the SSC project is to create a scientific laboratory in high energy physics whose facilities are unique. Ultimately the success of that laboratory will be measured by its scientific discoveries, measurements, interpretations, and innovations. Toward that end the accelerator-collider must be constructed to high standards at minimum cost and maximum effectiveness. Preparations must be made for future operations and a scientific-technical staff attracted and maintained. The chosen site must accommodate all of these factors. This document summarizes siting criteria for the SSC and enumerates site-specific information important to the evaluation of potential sites. This document is not a call for site proposals but a technical report prepared for the information and use of the Department of Energy (DOE).

  8. Missouri state information handbook formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and rgulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Missouri. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; a description of the organization and structure of local governments affected by remedial action at the St. Louis area sites; a summary of relevant local ordinances and regulations; an identification of relevant public interest groups; a list of radio stations, television stations and newspapers that provide public information to the St. Louis area or to Jefferson City; and the full text of relevant statutes and regulations

  9. Missouri State information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Missouri. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature chairmen, and a summary of recent relevant legislative action; a description of the organization and structure of local governments affected by remedial action at the St. Louis area sites; a summary of relevant local ordinances and regulations; an identification of relevant public interest groups; a list of radio stations, television stations, and newspapers that provide public information to the St. Louis area or to Jefferson City; and the full text of relevant statutes and regulations

  10. Missouri State information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Missouri. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature chairmen, and a summary of recent relevant legislative action; a description of the organization and structure of local governments affected by remedial action at the St. Louis area sites; a summary of relevant local ordinances and regulations; an identification of relevant public interest groups; a list of radio stations, television stations, and newspapers that provide public information to the St. Louis area or to Jefferson City; and the full text of relevant statutes and regulations.

  11. When is there sufficient information from the Site Investigations?

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Johan [JA Streamflow AB, Aelvsjoe (Sweden); Munier, Raymond; Stroem, Anders; Soederbaeck, Bjoern [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Almen, Karl-Erik [KEA Geo-konsult (Sweden); Olsson, Lars [Geostatistik AB, Tumba (Sweden)

    2004-04-01

    SKB has started site investigations for a deep repository for spent nuclear fuel at two different sites in Sweden. The investigations should provide necessary information for a licence application aimed at starting underground exploration. The investigations and analyses of them are supposed to provide the broad knowledge base that is required to achieve the overall goals of the site investigation phase. The knowledge will be utilized to evaluate the suitability of investigated sites for the deep repository and must be comprehensive enough to: Show whether the selected site satisfies requirements on safety and technical aspects. Serve as a basis for adaptation of the deep repository to the characteristics of the site with an acceptable impact on society and the environment. Permit comparisons with other investigated sites. Furthermore, the investigations are discontinued when the reliability of the site description has reached such a level that the body of data for safety assessment and design is sufficient, or until the body of data shows that the rock does not satisfy the requirements. These objectives are valid, but do not provide sufficient and concrete guidance. For this reason SKB has conducted this project which should acquire concrete guidance on how to judge when the surface based Site Investigation Phase does not need to continue. After a general assessment of the problem, the following specific objectives of the current work were identified: Demonstrate concretely how the assessed uncertainties in a Site Description based on a specific level of investigations, together with expected feedback from Safety Assessment and Engineering, can be used to decide whether the site investigations are sufficient - or need to continue. This demonstration will be based on a practical application of relevant aspects of decision analysis tools. Highlight and make concrete the type of feedback to be expected from Safety Assessment and Engineering and show how this feedback

  12. Illinois state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Illinois. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full text of relevant statutes and regulations

  13. Illinois State information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Illinois. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  14. Massachusetts state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1981-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of Massachusetts. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full text of relevant statutes and regulations

  15. Iowa state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1981-01-01

    This volume is one of a series produced under contract with the DOE, By Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of Iowa. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full test of relevant statutes and regulations

  16. Pennsylvania state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and State levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Pennsylvania. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  17. Massachusetts state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-09

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of Massachusetts. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full text of relevant statutes and regulations.

  18. California state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1981-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of California. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full text of relevant statutes and regulations

  19. Iowa state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-09

    This volume is one of a series produced under contract with the DOE, By Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of Iowa. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full test of relevant statutes and regulations.

  20. California state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-09

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of California. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full text of relevant statutes and regulations.

  1. Pennsylvania state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and State levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Pennsylvania. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  2. Oregon state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Oregon. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  3. Pennsylvania state information handbook formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Pennsylvania. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  4. Oregon state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Oregon. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  5. Oregon state information handbook formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administater, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Oregon. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  6. Maryland state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and State levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Maryland. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  7. Ohio state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1981-01-01

    This volume is one of a series produced under contract with the DOE, by POLITECH CORPORATION to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of Ohio. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full test of relevant statutes and regulations

  8. Ohio state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    1981-02-09

    This volume is one of a series produced under contract with the DOE, by POLITECH CORPORATION to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of Ohio. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; the full test of relevant statutes and regulations.

  9. Oregon state information handbook formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administater, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Oregon. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  10. Hard times in the city - attractive nest sites but insufficient food supply lead to low reproduction rates in a bird of prey.

    Science.gov (United States)

    Sumasgutner, Petra; Nemeth, Erwin; Tebb, Graham; Krenn, Harald W; Gamauf, Anita

    2014-01-01

    Urbanization is a global phenomenon that is encroaching on natural habitats and decreasing biodiversity, although it is creating new habitats for some species. The Eurasian kestrel (Falco tinnunculus) is frequently associated with urbanized landscapes but it is unclear what lies behind the high densities of kestrels in the urban environment. Occupied nest sites in the city of Vienna, Austria were investigated along a gradient of urbanization (percentage of land covered by buildings or used by traffic). Field surveys determined the abundance of potential prey (birds and rodents) and the results were compared to the birds' diets. A number of breeding parameters were recorded over the course of three years. The majority of kestrels breed in semi-natural cavities in historic buildings. Nearest neighbour distances (NND) were smallest and reproductive success lowest in the city centre. Abundance of potential prey was not found to relate to the degree of urbanization but there was a significant shift in the birds' diets from a heavy reliance on rodents in the outskirts of the city to feeding more on small birds in the centre. The use of urban habitats was associated with higher nest failure, partly associated with predation and nest desertion, and with significantly lower hatching rates and smaller fledged broods. High breeding densities in urban habitats do not necessarily correlate with high habitat quality. The high density of kestrel nests in the city centre is probably due to the ready availability of breeding cavities. Highly urbanized areas in Vienna are associated with unexpected costs for the city dwelling-raptor, in terms both of prey availability and of reproductive success. The kestrel appears to be exploiting the urban environment but given the poor reproductive performance of urban kestrels it is likely that the species is falling into an ecological trap.

  11. Hard times in the city – attractive nest sites but insufficient food supply lead to low reproduction rates in a bird of prey

    Science.gov (United States)

    2014-01-01

    Introduction Urbanization is a global phenomenon that is encroaching on natural habitats and decreasing biodiversity, although it is creating new habitats for some species. The Eurasian kestrel (Falco tinnunculus) is frequently associated with urbanized landscapes but it is unclear what lies behind the high densities of kestrels in the urban environment. Results Occupied nest sites in the city of Vienna, Austria were investigated along a gradient of urbanization (percentage of land covered by buildings or used by traffic). Field surveys determined the abundance of potential prey (birds and rodents) and the results were compared to the birds’ diets. A number of breeding parameters were recorded over the course of three years. The majority of kestrels breed in semi-natural cavities in historic buildings. Nearest neighbour distances (NND) were smallest and reproductive success lowest in the city centre. Abundance of potential prey was not found to relate to the degree of urbanization but there was a significant shift in the birds’ diets from a heavy reliance on rodents in the outskirts of the city to feeding more on small birds in the centre. The use of urban habitats was associated with higher nest failure, partly associated with predation and nest desertion, and with significantly lower hatching rates and smaller fledged broods. Conclusions High breeding densities in urban habitats do not necessarily correlate with high habitat quality. The high density of kestrel nests in the city centre is probably due to the ready availability of breeding cavities. Highly urbanized areas in Vienna are associated with unexpected costs for the city dwelling-raptor, in terms both of prey availability and of reproductive success. The kestrel appears to be exploiting the urban environment but given the poor reproductive performance of urban kestrels it is likely that the species is falling into an ecological trap. PMID:24872836

  12. Information sharing and relationships on social networking sites.

    Science.gov (United States)

    Steijn, Wouter M P; Schouten, Alexander P

    2013-08-01

    This article investigates the relationship between sharing personal information and relationship development in the context of social networking sites (SNSs). Information disclosed on these sites could affect relationships in a different manner compared to more traditional interactions, such as instant messaging or face-to-face interaction. Respondents in the age range of 12 to 83 were surveyed about experiences of relationship development as a consequence of contact through Facebook or Hyves-the most popular Dutch SNSs. Results showed a primarily positive effect of information sharing on SNSs on our relationships. Furthermore, relationship development mainly occurs among acquaintances and friends, and public posts are most strongly related to relationship development. These findings suggest that SNSs might affect relationships in a distinct fashion as acquaintances and friends gain access to public self-disclosures that might normally only be reserved for close friends and family. Overall, this study provides an insight into some of the positive aspects of the public nature of SNSs in contrast with the general negative associations.

  13. Handling Internet-Based Health Information: Improving Health Information Web Site Literacy Among Undergraduate Nursing Students.

    Science.gov (United States)

    Wang, Weiwen; Sun, Ran; Mulvehill, Alice M; Gilson, Courtney C; Huang, Linda L

    2017-02-01

    Patient care problems arise when health care consumers and professionals find health information on the Internet because that information is often inaccurate. To mitigate this problem, nurses can develop Web literacy and share that skill with health care consumers. This study evaluated a Web-literacy intervention for undergraduate nursing students to find reliable Web-based health information. A pre- and postsurvey queried undergraduate nursing students in an informatics course; the intervention comprised lecture, in-class practice, and assignments about health Web site evaluation tools. Data were analyzed using Wilcoxon and ANOVA signed-rank tests. Pre-intervention, 75.9% of participants reported using Web sites to obtain health information. Postintervention, 87.9% displayed confidence in using an evaluation tool. Both the ability to critique health Web sites (p = .005) and confidence in finding reliable Internet-based health information (p = .058) increased. Web-literacy education guides nursing students to find, evaluate, and use reliable Web sites, which improves their ability to deliver safer patient care. [J Nurs Educ. 2017;56(2):110-114.]. Copyright 2017, SLACK Incorporated.

  14. Construction site Voice Operated Information System (VOIS) test

    Science.gov (United States)

    Lawrence, Debbie J.; Hettchen, William

    1991-01-01

    The Voice Activated Information System (VAIS), developed by USACERL, allows inspectors to verbally log on-site inspection reports on a hand held tape recorder. The tape is later processed by the VAIS, which enters the information into the system's database and produces a written report. The Voice Operated Information System (VOIS), developed by USACERL and Automated Sciences Group, through a ESACERL cooperative research and development agreement (CRDA), is an improved voice recognition system based on the concepts and function of the VAIS. To determine the applicability of the VOIS to Corps of Engineers construction projects, Technology Transfer Test Bad (T3B) funds were provided to the Corps of Engineers National Security Agency (NSA) Area Office (Fort Meade) to procure and implement the VOIS, and to train personnel in its use. This report summarizes the NSA application of the VOIS to quality assurance inspection of radio frequency shielding and to progress payment logs, and concludes that the VOIS is an easily implemented system that can offer improvements when applied to repetitive inspection procedures. Use of VOIS can save time during inspection, improve documentation storage, and provide flexible retrieval of stored information.

  15. [Traumatic tricuspid insufficiency].

    Science.gov (United States)

    Vayre, F; Richard, P; Ollivier, J P

    1996-04-01

    Traumatic tricuspid insufficiency is a rare condition. The diagnosis is difficult because of the slow progression of this pathology and the presence of more clinically acute lesions. Non-penetrating chest trauma is responsible for 90% of cases. Echocardiography is the investigation of choice for assessing the mechanism of the tricuspid regurgitation and for diagnosing associated lesions. It should be performed systematically in patients with multiple trauma. The surgical indications are difficult to determine and depend on the patients' symptoms and the type of anatomical lesions. It should be undertaken before right ventricular myocardial dysfunction. Several techniques may be used from valvuloplasty to valve replacement mainly with bioprostheses in symptomatic patients.

  16. Federal government information handbook formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the Federal Government. It contains: a summary of the organization and responsibilities of agencies within the executive branch of the Federal government which may be relevant to FUSRAP activities; a brief summary of relevant Federal statutes and regulations; a description of the structure of the US Congress, identification of the officers, relevant committees and committee chairmen; a description of the Federal legislative process; a summary of legislation enacted and considered in the recently-adjourned 96th Congress; a description of the Federal budgetary process; a summary of the Carter Administration's comprehensive radioactive waste management program; and excerpts from the text of relevant Federal statutes and regulations

  17. Federal government information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the Federal Government. It contains a summary of the organization and responsibilities of agencies within the executive branch of the Federal government which may be relevant to FUSRAP activities; a brief summary of relevant Federal statutes and regulations; a description of the structure of the US Congress, identification of the officers, relevant committees and committee chairmen; a description of the Federal legislative process; a summary of legislation enacted and considered in the recently-adjourned 96th Congress; a description of the Federal budgetary process; a summary of the Carter Administration's comprehensive radioactive waste management program; and excerpts from the text of relevant federal statutes and regulations

  18. Federal government information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the Federal Government. It contains a summary of the organization and responsibilities of agencies within the executive branch of the Federal government which may be relevant to FUSRAP activities; a brief summary of relevant Federal statutes and regulations; a description of the structure of the US Congress, identification of the officers, relevant committees and committee chairmen; a description of the Federal legislative process; a summary of legislation enacted and considered in the recently-adjourned 96th Congress; a description of the Federal budgetary process; a summary of the Carter Administration's comprehensive radioactive waste management program; and excerpts from the text of relevant federal statutes and regulations.

  19. Fatigue and insufficiency fractures

    International Nuclear Information System (INIS)

    Lodwick, G.S.; Rosenthal, D.I.; Kattapuram, S.V.; Hudson, T.M.

    1987-01-01

    The incidence of stress fracture is increasing. In our younger society this is due largely to a preocupation with physical conditioning, but in our elderly population it is due to improved recognition and better methods of detection and diagnosis. Stress fracture of the elderly is an insufficiency fracture which occurs in the spine, the pelvis, the sacrum and other bones afflicted with disorders which cause osteopenia. Stress fracture is frequently misdiagnosed as a malignant lesion of bone resulting in biopsy. Scintiscanning provides the greatest frequency of detection, while computed tomography often provides the definitive diagnosis. With increased interest and experience a better insight into the disease has been achieved, and what was once thought of as a simple manifestation of mechanical stress is now known to be an orderly, complex pattern of physiological changes in bone which conform to a model by Frost. The diffuse nature of these changes can be recognized by scintigraphy, radiography and magnetic resonance imaging. 27 refs.; 8 figs

  20. Managing Adrenal Insufficiency

    Science.gov (United States)

    ... a child, use the dose prescribed by the health care provider 8. Replace the needle cap 9. Select your injection site. To inject yourself safely, become familiar with your body. Undress your thigh, and look ...

  1. Quality and accuracy of sexual health information web sites visited by young people.

    Science.gov (United States)

    Buhi, Eric R; Daley, Ellen M; Oberne, Alison; Smith, Sarah A; Schneider, Tali; Fuhrmann, Hollie J

    2010-08-01

    We assessed online sexual health information quality and accuracy and the utility of web site quality indicators. In reviewing 177 sexual health web sites, we found below average quality but few inaccuracies. Web sites with the most technically complex information and/or controversial topics contained the most inaccuracies. We found no association between inaccurate information and web site quality. (c) 2010 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  2. [Addison's disease : Primary adrenal insufficiency].

    Science.gov (United States)

    Pulzer, A; Burger-Stritt, S; Hahner, S

    2016-05-01

    Adrenal insufficiency, a rare disorder which is characterized by the inadequate production or absence of adrenal hormones, may be classified as primary adrenal insufficiency in case of direct affection of the adrenal glands or secondary adrenal insufficiency, which is mostly due to pituitary or hypothalamic disease. Primary adrenal insufficiency affects 11 of 100,000 individuals. Clinical symptoms are mainly nonspecific and include fatigue, weight loss, and hypotension. The diagnostic test of choice is dynamic testing with synthetic ACTH. Patients suffering from chronic adrenal insufficiency require lifelong hormone supplementation. Education in dose adaption during physical and mental stress or emergency situations is essential to prevent life-threatening adrenal crises. Patients with adrenal insufficiency should carry an emergency card and emergency kit with them.

  3. Study of acute renal insufficiency and chronic renal insufficiency using radioisotopes

    International Nuclear Information System (INIS)

    Raynaud, C.

    1976-01-01

    Radioisotopic renal function tests are of assistance to diagnose and follow-up the course of renal insufficiency. The radioisotopic renogram is useful in assessing the response to therapy of child obstructive uropathies and evaluating renal transplant function. The renal scan is helpful, in an emergency service, to differenciate chronic renal insufficiency from acute renal insufficiency. Hg renal uptake test provides informations on physiopathological problems. Among them, the following problems are emphasized: evolution of a nonfunctioning kidney, control of the success of a reparative surgery and of bilateral obstructive uropathies with unilateral symptoms [fr

  4. 76 FR 2144 - Quest Diagnostics, Inc. Information Technology Help Desk Services Including On-Site Leased...

    Science.gov (United States)

    2011-01-12

    .... Information Technology Help Desk Services Including On-Site Leased Workers From Modis, West Norriton, PA..., applicable to workers of Quest Diagnostics, Inc., Information Technology Help Desk Services, West Norriton... Quest Diagnostics, Inc., Information Technology Help Desk [[Page 2145

  5. 76 FR 81959 - Notice of Proposed Information Collection: Comment Request; Homelessness Prevention Study Site...

    Science.gov (United States)

    2011-12-29

    ... Information Collection: Comment Request; Homelessness Prevention Study Site Visits AGENCY: Office of the Chief.... This Notice also lists the following information: Title of Proposal: Homelessness Prevention Study Site... of the Paperwork Reduction Act requirements associated with HUD's Homelessness Prevention Study Site...

  6. Insufficiency fracture after radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Dong Ryul; Huh, Seung Jae [Dept.of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2014-12-15

    Insufficiency fracture occurs when normal or physiological stress applied to weakened bone with demineralization and decreased elastic resistance. Recently, many studies reported the development of IF after radiation therapy (RT) in gynecological cancer, prostate cancer, anal cancer and rectal cancer. The RT-induced insufficiency fracture is a common complication during the follow-up using modern imaging studies. The clinical suspicion and knowledge the characteristic imaging patterns of insufficiency fracture is essential to differentiate it from metastatic bone lesions, because it sometimes cause severe pain, and it may be confused with bone metastasis.

  7. Value of Information Analysis Project Gnome Site, New Mexico

    International Nuclear Information System (INIS)

    Pohll, Greg; Chapman, Jenny

    2010-01-01

    The Project Gnome site in southeastern New Mexico was the location of an underground nuclear detonation in 1961 and a hydrologic tracer test using radionuclides in 1963. The tracer test is recognized as having greater radionuclide migration potential than the nuclear test because the tracer test radionuclides (tritium, 90Sr, 131I, and 137Cs) are in direct contact with the Culebra Dolomite aquifer, whereas the nuclear test is within a bedded salt formation. The tracer test is the topic here. Recognizing previous analyses of the fate of the Gnome tracer test contaminants (Pohll and Pohlmann, 1996; Pohlmann and Andricevic, 1994), and the existence of a large body of relevant investigations and analyses associated with the nearby Waste Isolation Pilot Plant (WIPP) site (summarized in US DOE, 2009), the Gnome Site Characterization Work Plan (U.S. DOE, 2002) called for a Data Decision Analysis to determine whether or not additional characterization data are needed prior to evaluating existing subsurface intrusion restrictions and determining long-term monitoring for the tracer test. Specifically, the Work Plan called for the analysis to weigh the potential reduction in uncertainty from additional data collection against the cost of such field efforts.

  8. Adrenal Insufficiency and Addison's Disease

    Science.gov (United States)

    ... These conditions can lead to an adrenal crisis. Pregnancy Women with adrenal insufficiency who become pregnant are ... can benefit from following a diet rich in sodium. A health care provider or a dietitian can ...

  9. Acquisition Information Management system telecommunication site survey results

    Energy Technology Data Exchange (ETDEWEB)

    Hake, K.A. [Oak Ridge National Lab., TN (United States); Key, B.G. [COR, Inc., Oak Ridge, TN (United States)

    1993-09-01

    The Army acquisition community currently uses a dedicated, point-to-point secure computer network for the Army Material Plan Modernization (AMPMOD). It must transition to the DOD supplied Defense Secure Network 1 (DSNET1). This is one of the first networks of this size to begin the transition. The type and amount of computing resources available at individual sites may or may not meet the new network requirements. This task surveys these existing telecommunications resources available in the Army acquisition community. It documents existing communication equipment, computer hardware, associated software, and recommends appropriate changes.

  10. Evaluating Mobile Phones and Web Sites for Academic Information Needs

    OpenAIRE

    Muhammad Farhan; Nadeem Akhtar; Amnah Firdous; Malik Muhammad Saad Missen; Muhammad Ali Nizamani; Hina Asmat

    2016-01-01

    In the last decade, there has been an exponential growth in use of mobile phones among people. Smart phone invention has digitized life of a common man especially after introduction of 3G/4G technology. People are used to use Internet on the move because of this advancement in technology. This advancement has also motivated usability design researchers to propose more usable designs for both smart phones and web sites. This work focuses on evaluation of web usability of mobile phones as well ...

  11. Maryland State information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Handbook Series Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Maryland. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  12. Maryland State information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Handbook Series Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Maryland. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  13. Florida state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1981-01-01

    This volume is one of a series produced under contract with DOE, Office of Nuclear Waste Management, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the federal and state levels, the pertinent programs they administer, each affected state legislature, and current federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Florida. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  14. Florida state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-02-27

    This volume is one of a series produced under contract with DOE, Office of Nuclear Waste Management, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the federal and state levels, the pertinent programs they administer, each affected state legislature, and current federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of Florida. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  15. Social internet sites as a source of public health information.

    Science.gov (United States)

    Vance, Karl; Howe, William; Dellavalle, Robert P

    2009-04-01

    Social media websites, such as YouTube, Facebook, MySpace, Twitter, and Second Life are rapidly emerging as popular sources of health information especially for teens and young adults. Social media marketing carries the advantages of low cost, rapid transmission through a wide community, and user interaction. Disadvantages include blind authorship, lack of source citation, and presentation of opinion as fact. Dermatologists and other health care providers should recognize the importance of social media websites and their potential usefulness for disseminating health information.

  16. Information report on nuclear safety and radiation protection of the Tricastin AREVA site, 2010 edition

    International Nuclear Information System (INIS)

    2010-01-01

    This report presents the Tricastin site, the different arrangements concerning nuclear safety and radiation protection on this site, and recent nuclear events. It describes how site releases are managed and how the environment is controlled and monitored, how wastes are managed, and how other impacts are controlled. It finally presents the different actions regarding transparency and information

  17. Tags in Domain-Specific Sites - New Information?

    DEFF Research Database (Denmark)

    Steinhauer, Jeremy; Delcambre, Lois M.L.; Maier, David

    2011-01-01

    If researchers use tags in retrieval applications they might assume, implicitly, that tags represent novel information, e.g., when they attribute performance improvement in their retrieval algorithm(s) to the use of tags. In this work, we investigate whether this assumption is true. We focus on t...

  18. Guidelines for medical and health information sites on the internet: principles governing AMA web sites. American Medical Association.

    Science.gov (United States)

    Winker, M A; Flanagin, A; Chi-Lum, B; White, J; Andrews, K; Kennett, R L; DeAngelis, C D; Musacchio, R A

    Access to medical information via the Internet has the potential to speed the transformation of the patient-physician relationship from that of physician authority ministering advice and treatment to that of shared decision making between patient and physician. However, barriers impeding this transformation include wide variations in quality of content on the Web, potential for commercial interests to influence online content, and uncertain preservation of personal privacy. To address these issues, the American Medical Association (AMA) has developed principles to guide development and posting of Web site content, govern acquisition and posting of online advertising and sponsorship, ensure site visitors' and patients' rights to privacy and confidentiality, and provide effective and secure means of e-commerce. While these guidelines were developed for the AMA Web sites and visitors to these sites, they also may be useful to other providers and users of medical information on the Web. These principles have been developed with the understanding that they will require frequent revision to keep pace with evolving technology and practices on the Internet. The AMA encourages review and feedback from readers, Web site visitors, policymakers, and all others interested in providing reliable quality information via the Web.

  19. Discovery and information-theoretic characterization of transcription factor binding sites that act cooperatively.

    Science.gov (United States)

    Clifford, Jacob; Adami, Christoph

    2015-09-02

    Transcription factor binding to the surface of DNA regulatory regions is one of the primary causes of regulating gene expression levels. A probabilistic approach to model protein-DNA interactions at the sequence level is through position weight matrices (PWMs) that estimate the joint probability of a DNA binding site sequence by assuming positional independence within the DNA sequence. Here we construct conditional PWMs that depend on the motif signatures in the flanking DNA sequence, by conditioning known binding site loci on the presence or absence of additional binding sites in the flanking sequence of each site's locus. Pooling known sites with similar flanking sequence patterns allows for the estimation of the conditional distribution function over the binding site sequences. We apply our model to the Dorsal transcription factor binding sites active in patterning the Dorsal-Ventral axis of Drosophila development. We find that those binding sites that cooperate with nearby Twist sites on average contain about 0.5 bits of information about the presence of Twist transcription factor binding sites in the flanking sequence. We also find that Dorsal binding site detectors conditioned on flanking sequence information make better predictions about what is a Dorsal site relative to background DNA than detection without information about flanking sequence features.

  20. Web site lets solar scientists inform and inspire students

    Science.gov (United States)

    Hauck, Karin

    2012-07-01

    Where on the Web can a middle school girl ask a female solar scientist about solar storms, the course and behavior of charged solar particles, and the origin of the Sun's dynamo—and also find out what the scientist was like as a child, whether the scientist has tattoos or enjoys snowboarding, what she likes and dislikes about her career, and how she balances her energy for work and family life? These kinds of exchanges happen at Solar Week (http://www.solarweek.org; see Figure 1). Established in 2000, Solar Week is an online resource for middle and lower high school students about the science of the Sun, sponsored by the Center for Science Education at the Space Sciences Laboratory (CSE@SSL) at the University of California, Berkeley (UC Berkeley). The Web site's goals are to educate students about the Sun and solar physics and to encourage future careers in science—especially for girls. One way is by giving solar scientists the chance to be relatable role models, to answer students' questions, and to share their experiences in an online forum.

  1. Public transparency Web sites for radiology practices: prevalence of price, clinical quality, and service quality information.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Doshi, Ankur M

    2016-01-01

    To assess information regarding radiology practices on public transparency Web sites. Eight Web sites comparing radiology centers' price and quality were identified. Web site content was assessed. Six of eight Web sites reported examination prices. Other reported information included hours of operation (4/8), patient satisfaction (2/8), American College of Radiology (ACR) accreditation (3/8), on-site radiologists (2/8), as well as parking, accessibility, waiting area amenities, same/next-day reports, mammography follow-up rates, examination appropriateness, radiation dose, fellowship-trained radiologists, and advanced technologies (1/8 each). Transparency Web sites had a preponderance of price (and to a lesser extent service quality) information, risking fostering price-based competition at the expense of clinical quality. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Prospective analysis of the quality of Spanish health information web sites after 3 years.

    Science.gov (United States)

    Conesa-Fuentes, Maria C; Hernandez-Morante, Juan J

    2016-12-01

    Although the Internet has become an essential source of health information, our study conducted 3 years ago provided evidence of the low quality of Spanish health web sites. The objective of the present study was to evaluate the quality of Spanish health information web sites now, and to compare these results with those obtained 3 years ago. For the original study, the most visited health information web sites were selected through the PageRank® (Google®) system. The present study evaluated the quality of the same web sites from February to May 2013, using the method developed by Bermúdez-Tamayo et al. and HONCode® criteria. The mean quality of the selected web sites was low and has deteriorated since the previous evaluation, especially in regional health services and institutions' web sites. The quality of private web sites remained broadly similar. Compliance with privacy and update criteria also improved in the intervening period. The results indicate that, even in the case of health web sites, design or appearance is more relevant to developers than quality of information. It is recommended that responsible institutions should increase their efforts to eliminate low-quality health information that may further contribute to health problems.

  3. Hand Society and Matching Program Web Sites Provide Poor Access to Information Regarding Hand Surgery Fellowship.

    Science.gov (United States)

    Hinds, Richard M; Klifto, Christopher S; Naik, Amish A; Sapienza, Anthony; Capo, John T

    2016-08-01

    The Internet is a common resource for applicants of hand surgery fellowships, however, the quality and accessibility of fellowship online information is unknown. The objectives of this study were to evaluate the accessibility of hand surgery fellowship Web sites and to assess the quality of information provided via program Web sites. Hand fellowship Web site accessibility was evaluated by reviewing the American Society for Surgery of the Hand (ASSH) on November 16, 2014 and the National Resident Matching Program (NRMP) fellowship directories on February 12, 2015, and performing an independent Google search on November 25, 2014. Accessible Web sites were then assessed for quality of the presented information. A total of 81 programs were identified with the ASSH directory featuring direct links to 32% of program Web sites and the NRMP directory directly linking to 0%. A Google search yielded direct links to 86% of program Web sites. The quality of presented information varied greatly among the 72 accessible Web sites. Program description (100%), fellowship application requirements (97%), program contact email address (85%), and research requirements (75%) were the most commonly presented components of fellowship information. Hand fellowship program Web sites can be accessed from the ASSH directory and, to a lesser extent, the NRMP directory. However, a Google search is the most reliable method to access online fellowship information. Of assessable programs, all featured a program description though the quality of the remaining information was variable. Hand surgery fellowship applicants may face some difficulties when attempting to gather program information online. Future efforts should focus on improving the accessibility and content quality on hand surgery fellowship program Web sites.

  4. 40 CFR 1400.9 - Access to off-site consequence analysis information by State and local government officials.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Access to off-site consequence... CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Access to Off-Site Consequence Analysis Information by Government Officials. § 1400.9 Access to off-site consequence analysis...

  5. Site characterization information needs for a high-level waste geologic repository

    International Nuclear Information System (INIS)

    Gupta, D.C.; Nataraja, M.S.; Justus, P.S.

    1987-01-01

    At each of the three candidate sites recommended for site characterization for High-Level Waste Geologic Repository development, the DOE has proposed to conduct both surface-based testing and in situ exploration and testing at the depths that wastes would be emplaced. The basic information needs and consequently the planned surface-based and in situ testing program will be governed to a large extent by the amount of credit taken for individual components of the geologic repository in meeting the performance objectives and siting criteria. Therefore, identified information to be acquired from site characterization activities should be commensurate with DOE's assigned performance goals for the repository system components on a site-specific basis. Because of the uncertainties that are likely to be associated with initial assignment of performance goals, the information needs should be both reasonably and conservatively identified

  6. The Quality of Information about Hip Fractures in Turkish Internet Sites

    Directory of Open Access Journals (Sweden)

    Fatih Küçükdurmaz

    2013-05-01

    Full Text Available Aim: Internet has been the most commonly used way to access information now. Patients and their families search information about diseases and treatment methods on web. Our aim is to check the information quality of Turkish language based web sites that mention about hip fractures. Material and Method: We made a search by the word ‘hip fracture’ with three web search engines which are most popular in Turkey. We evaluated the most commonly visited first 10 sites and scored them according to a standard form. Results: Nine of the 30 web sites were include useful information for patients about the subject. The total score was 7.0 (min.:2, max.:14, SD: 4.81 Discussion: The web sites designed in Turkish that contains information about the health topics was found to be inadequate. This incomplete and incorrect information can lead to the users false informed about the topic. In this regard, the development of new sites is needed that can objectively accreditate health-related sites.

  7. E-KIT: An Electronic-Knowledge Information Tool for Organizing Site Information and Improving Technical Communication with Stakeholders - 13082

    International Nuclear Information System (INIS)

    Kautsky, Mark; Findlay, Richard C.; Hodges, Rex A.

    2013-01-01

    Managing technical references for projects that have long histories is hampered by the large collection of documents, each of which might contain discrete pieces of information relevant to the site conceptual model. A database application has been designed to improve the efficiency of retrieving technical information for a project. Although many databases are currently used for accessing analytical and geo-referenced data, applications designed specifically to manage technical reference material for projects are scarce. Retrieving site data from the array of available references becomes an increasingly inefficient use of labor. The electronic-Knowledge Information Tool (e-KIT) is designed as a project-level resource to access and communicate technical information. The e-KIT is a living tool that grows as new information becomes available, and its value to the project increases as the volume of site information increases. Having all references assembled in one location with complete reference citations and links to elements of the site conceptual model offers a way to enhance communication with outside groups. The published and unpublished references are incorporated into the e-KIT, while the compendium of references serves as a complete bibliography for the project. (authors)

  8. E-KIT: An Electronic-Knowledge Information Tool for Organizing Site Information and Improving Technical Communication with Stakeholders - 13082

    Energy Technology Data Exchange (ETDEWEB)

    Kautsky, Mark [U.S. Department of Energy Office of Legacy Management, 2597 Legacy Way, Grand Junction CO 81503 (United States); Findlay, Richard C.; Hodges, Rex A. [Stoller LMS Team, 2597 Legacy Way, Grand Junction CO 81503 (United States)

    2013-07-01

    Managing technical references for projects that have long histories is hampered by the large collection of documents, each of which might contain discrete pieces of information relevant to the site conceptual model. A database application has been designed to improve the efficiency of retrieving technical information for a project. Although many databases are currently used for accessing analytical and geo-referenced data, applications designed specifically to manage technical reference material for projects are scarce. Retrieving site data from the array of available references becomes an increasingly inefficient use of labor. The electronic-Knowledge Information Tool (e-KIT) is designed as a project-level resource to access and communicate technical information. The e-KIT is a living tool that grows as new information becomes available, and its value to the project increases as the volume of site information increases. Having all references assembled in one location with complete reference citations and links to elements of the site conceptual model offers a way to enhance communication with outside groups. The published and unpublished references are incorporated into the e-KIT, while the compendium of references serves as a complete bibliography for the project. (authors)

  9. Developing and promoting an intranet site for a drug information service.

    Science.gov (United States)

    Costerison, Emily C; Graham, Angie S

    2008-04-01

    The development and promotion of a drug information service (DIS) intranet site are described. Stanford Hospital and Clinics (SHC) is an acute and tertiary care facility with 613 licensed inpatient beds and 48 outpatient clinics. A DIS intranet site was developed to allow better accessibility to pharmacy forms and products (e.g., drug shortage list, reference guides) and to reduce repetitive requests to the DIS. The goal was to continue to provide information to SHC health care providers but allow the drug information specialist to focus on answering clinical questions. The intranet site was completed over a four-month period. The intranet site was divided into seven webpages: DIS overview, pharmacy and therapeutics, frequently asked questions, quick drug reference guide, ask the pharmacist, drug information resources, and referral center. The preparation for and implementation of the promotional phase took approximately two months. Promotional strategies included the creation and dissemination of brochures and stickers. The intranet site went live on January 1, 2007, and the advertising campaign began one month later. The utility of the site was measured for five months by tracking the number of visits to the site, the number of visits to each webpage, and the number of downloaded files. Request volume, caller affiliation, and question types received by the DIS call center were also recorded. Establishing a DIS intranet site required a considerable time investment and a willingness to work with existing infrastructures, such as the marketing and communications department and Web marketing staff.

  10. EnTagRec : an enhanced tag recommendation system for software information sites

    NARCIS (Netherlands)

    Wang, S.; Lo, D.; Vasilescu, B.N.; Serebrenik, A.

    2014-01-01

    Software engineers share experiences with modern technologies by means of software information sites, such as STACK OVERFLOW. These sites allow developers to label posted content, referred to as software objects, with short descriptions, known as tags. However, tags assigned to objects tend to be

  11. Decision-making in honeybee swarms based on quality and distance information of candidate nest sites.

    Science.gov (United States)

    Laomettachit, Teeraphan; Termsaithong, Teerasit; Sae-Tang, Anuwat; Duangphakdee, Orawan

    2015-01-07

    In the nest-site selection process of honeybee swarms, an individual bee performs a waggle dance to communicate information about direction, quality, and distance of a discovered site to other bees at the swarm. Initially, different groups of bees dance to represent different potential sites, but eventually the swarm usually reaches an agreement for only one site. Here, we model the nest-site selection process in honeybee swarms of Apis mellifera and show how the swarms make adaptive decisions based on a trade-off between the quality and distance to candidate nest sites. We use bifurcation analysis and stochastic simulations to reveal that the swarm's site distance preference is moderate>near>far when the swarms choose between low quality sites. However, the distance preference becomes near>moderate>far when the swarms choose between high quality sites. Our simulations also indicate that swarms with large population size prefer nearer sites and, in addition, are more adaptive at making decisions based on available information compared to swarms with smaller population size. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. A critical evaluation of Web sites offering patient information on tinnitus.

    LENUS (Irish Health Repository)

    Kieran, Stephen M

    2012-02-01

    The Internet is a vast information resource for both patients and healthcare professionals. However, the quality and content often lack formal scrutiny, so we examined the quality of patient information regarding tinnitus on the Internet. Using the three most popular search engines (google.com, yahoo.com, and msn.com), we found pertinent Web sites using the search term tinnitus. Web sites\\' accountability and authorship were evaluated using previously published criteria. The quality of patient information about tinnitus was assessed using a new 10-point scale, the Tinnitus Information Value (TIV). Statistical analysis was performed using the independent sample t-test (p sites was constructed using the first 30 English-language Web sites identified by each search engine. After duplicates and sites only containing links to other Web sites were eliminated, 39 remained. The mean score for accountability was 2.13 on scale of 0 to 7. The mean TIV was 5.0 on a scale of 0 to 10. Only 12 sites (30.8%) had their authors clearly identified. Twenty-two (56.4%) sites were sponsored by commercial interests or represented private practices. The mean TIV was significantly higher (p = 0.037) for noncommercial (personal, academic institution, or charity) sites (5.88 +\\/- 2.39 SD) than those representing commercial interests (4.32 +\\/- 2.10 SD). Tinnitus information available on the Internet is indeed variable, and care should be taken in recommending tinnitus Web sites to patients.

  13. Beyond Information Architecture: A Systems Integration Approach to Web-site Design

    Directory of Open Access Journals (Sweden)

    Krisellen Maloney

    2017-09-01

    Full Text Available Users' needs and expectations regarding access to information have fundamentally changed, creating a disconnect between how users expect to use a library Web site and how the site was designed. At the same time, library technical infrastructures include legacy systems that were not designedf or the Web environment. The authors propose a framework that combines elements of information architecture with approaches to incremental system design and implementation. The framework allows for the development of a Web site that is responsive to changing user needs, while recognizing the need for libraries to adopt a cost-effective approach to implementation and maintenance.

  14. [Adrenal insufficiency of the adult].

    Science.gov (United States)

    Jublanc, C; Bruckert, E

    2016-12-01

    Adrenal insufficiency is a rare but life-threatening disorder. Clinical manifestations include fatigue, weight loss, gastrointestinal manifestations and skin hyperpigmentation, the latter being specific of primary adrenal failure. Because of non-specific clinical features of this rare disorder, diagnosis can be delayed and adrenal failure be revealed by an acute crisis. Adrenal insufficiency can be primary (Addison disease), most frequently autoimmune, or secondary, resulting from long term administration of exogenous glucocorticoids or more rarely from pituitary disorders. Monitoring of substitutive treatment is now well codified. Patient education is very important in this chronic disease that remains associated with a persistent high risk of adrenal crisis. Copyright © 2016 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  15. Primary ovarian insufficiency: an update

    Directory of Open Access Journals (Sweden)

    Cox L

    2014-02-01

    Full Text Available Leticia Cox, James H LiuUH Case Medical Center, MacDonald Women's Hospital, Department of Obstetrics and Gynecology, Case Western Reserve University School of Medicine, Department of Reproductive Biology, Cleveland, OH, USAAbstract: Primary ovarian insufficiency is a condition that represents impaired ovarian function on a continuum with intermittent ovulation. This condition commonly leads to premature menopause, defined as cessation of ovulation prior to the age of 40 years. Because there are potential immediate and long-term consequences of hypoestrogenism, a timely diagnosis is invaluable. This comprehensive review will discuss identifiable causes for primary ovarian insufficiency, including genetic disorders and metabolic abnormalities, as well as review current strategies for diagnosis, evaluation, and management of women with this condition.Keywords: premature ovarian failure, premature menopause, ovarian dysfunction

  16. Information management fiscal year 1996 site support program plan, WBS 6.4. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    In the recent past, information resource management (IRM) was a neatly separable component of the overall DOE mission, concerned primarily with procuring and implementing automatic data processing (ADP) systems. As the DOE missions have shifted from producing product to managing processes, those clear lines have blurred. Today, IRM is firmly embedded in all aspects of the DOE mission. BCS Richland, Inc., (BCSR) provides IRM for the Hanford Site. The main focus in executing this mission is to meet customer goals by providing high-quality, timely, and cost-effective electronic communication, computing, and information services. Information resources provide the US Department of Energy, Richland Operations Office (RL) and the Hanford Site contractors the ability to generate, store, access, and communicate information quickly, reliably, and cost effectively. BCSR plans, implements, and operates electronic communication, computing and information management systems that enable effective operation of the Hanford Site. Five strategic initiatives to encompass the vision provide guidance and focus to the information technology (IT) direction for developing the BCSR program plan. These strategic initiatives are the program vision and are as follows: primary focus; fast response; accessible information; world class information management infrastructure; powerful desktop. The business directions that guide the development of the BCSR Program Plan are: (1) emphasize providing cost-effective and value-added communication, computing, and information systems products and services to the Site missions; (2) strengthen the alignment of products and services with Site projects and programs and eliminate duplications Sitewide; (3) focus on the effective resolution of critical Site information management (IM) issues.

  17. Technical Site Information: Planning group of the Directorate and Conventional Construction Division

    International Nuclear Information System (INIS)

    1993-11-01

    This document presents the technical site information for the Superconducting Super Collider project. The Ellis County, Texas site was selected by the Department of Energy in 1989. After assembling the initial staff at temporary facilities in Dallas, the SSC Laboratory began site-specific design work. The resulting design for the SSC accelerators, experimental areas, and laboratory facilities were described in the Site-Specific Conceptual Design Report of July 1990. Since then, design specifications for the technical components and conventional facilities have been formulated. In fact, a very significant amount of surface and underground construction has been initiated and many buildings have been completed. Testing of prototypes for most technical components is advanced. The construction phase of the SSC project is approximately 20% complete. At this time, it is appropriate to capture the conventional design work which has taken place since 1990. This documents records regional and physical information used in site studies, summarizes the site studies for conventional facilities, and presents site layouts for buildings and utilities as they would have been at the end of the construction project. As such, this documents summarizes and complements the work of many groups in the SSC laboratory, the Texas National Research Laboratory Commission (TNRLC), and several subcontractors to the SSC project. The document contains extensive references to their work contained in other drafts and final reports. In particular, it borrows heavily from the Site Development Plan (released in draft form in January, 1992) which has, to date, guided aspects of site development

  18. Technical Site Information: Planning group of the Directorate and Conventional Construction Division

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-11-01

    This document presents the technical site information for the Superconducting Super Collider project. The Ellis County, Texas site was selected by the Department of Energy in 1989. After assembling the initial staff at temporary facilities in Dallas, the SSC Laboratory began site-specific design work. The resulting design for the SSC accelerators, experimental areas, and laboratory facilities were described in the Site-Specific Conceptual Design Report of July 1990. Since then, design specifications for the technical components and conventional facilities have been formulated. In fact, a very significant amount of surface and underground construction has been initiated and many buildings have been completed. Testing of prototypes for most technical components is advanced. The construction phase of the SSC project is approximately 20% complete. At this time, it is appropriate to capture the conventional design work which has taken place since 1990. This documents records regional and physical information used in site studies, summarizes the site studies for conventional facilities, and presents site layouts for buildings and utilities as they would have been at the end of the construction project. As such, this documents summarizes and complements the work of many groups in the SSC laboratory, the Texas National Research Laboratory Commission (TNRLC), and several subcontractors to the SSC project. The document contains extensive references to their work contained in other drafts and final reports. In particular, it borrows heavily from the Site Development Plan (released in draft form in January, 1992) which has, to date, guided aspects of site development.

  19. Configuration system development of site and environmental information for radwaste disposal facility

    International Nuclear Information System (INIS)

    Park, Se-Moon; Yoon, Bong-Yo; Kim, Chang-Lak

    2005-01-01

    License for the nuclear facilities such as radioactive waste repository demands documents of site characterization, environmental assessment and safety assessment. This performance will produce bulk of the relevant data. For the safe management of radioactive waste repository, data of the site and environment have to be collected and managed systematically. Particularly for the radwaste repository, which has to be institutionally controlled for a long period after closure, the data will be collected and maintained through the monitoring programme. To meet this requirement, a new programme called 'Site Information and Total Environmental data management System (SITES)' has been developed. The scope and function of the SITES is issued in data DB, safety assessment and monitoring system. In this respect, SITES is designed with two modules of the SITES Database Module (SDM) and the Monitoring and Assesment (M and A). The SDM module is composed of three sub-modules. One is the Site Information Management System (SIMS), which manages data of site characterization such as topography, geology, hydrogeology, engineering geology, etc. The other is the ENVironmental Information management System (ENVIS) and Radioactive ENVironmental Information management System (RENVIS), which manage environmental data required for environmental assessment performance. ENVIS and RENVIS covered almost whole items of environmental assessment report required by Korean government. The SDM was constructed based on Entity Relationship Diagram produced from each item. Also using ArcGIS with the spatial characteristics of the data, it enables groundwater and water property monitoring networks, etc. To be analyzed in respect of every theme. The sub-modules of M and A called the Site and Environment Monitoring System (SEMS) and the Safety Assessment System (SAS) were developed. SEMS was designed to manage the inspection records of the individual measuring instruments and facilities, and the on

  20. Do corporate Web sites in Africa communicate investor information according to best practice guidelines?

    Directory of Open Access Journals (Sweden)

    G. Nel

    2007-11-01

    Full Text Available Corporate Web sites have become very popular media of information over the past decade. The Investor Relations Society published best practice Web site guidelines in December 2006 to guide companies seeking to improve the quality of their on-line communication with investors via their corporate Web sites. Guidelines were given for presentation (the way in which information is communicated and content (the information that is communicated. This study focused only on content. A 20-point checklist was developed from the prescribed best practice. The checklist focused on the six categories of best practice that entail company information, annual reports of the current year and archive, relevant news, shareholder information, bondholder information, corporate governance and corporate responsibility. Seventy-eight companies in Africa (40 from South Africa and 38 from the 'rest of Africa', that is Egypt, Kenya, Morocco, Nigeria and Tunisia were evaluated against this checklist. Companies from the 'rest of Africa' rated lower than South African companies in all categories on the checklist. Although South African companies received ratings above 90% for all categories, besides bondholder information, many of these companies do not supply shareholder, corporate governance and corporate responsibility information via dedicated sections on their corporate Web sites. The results for companies from the 'rest of Africa' were disappointing, especially with regard to communication of annual reports, shareholder information, bondholder information and corporate responsibility. Although possible reasons for these disappointing results are discussed in this study, further research should be conducted to determine the reason(s why important elements of information are not communicated via corporate Web sites.

  1. 78 FR 54241 - Proposed Information Collection; Comment Request; BroadbandMatch Web Site Tool

    Science.gov (United States)

    2013-09-03

    ... goal of increased broadband deployment and use in the United States. The BroadbandMatch Web site began... proposed collection of information is necessary for the proper performance of the functions of the agency... the quality, utility, and clarity of the information to be collected; and (d) ways to minimize the...

  2. LTAR information management: Six examples of data intensive work at site and network levels

    Science.gov (United States)

    Information systems for managing research data from the Long-term Agroecosystem Research (LTAR) program are implemented at site and network levels. Different information management tools are necessary to manage a variety of data types. There is no one-size fits all solution for managing all LTAR dat...

  3. Geographical information system (GIS) suitability analysis of radioactive waste repository site in Pahang, Malaysia

    International Nuclear Information System (INIS)

    Faizal Azrin Abd Razalim; Noraini Surip; Ahmad Hasnulhadi; Nazran Harun; Nurul Nadia Abd Malek; Roziah Che Musa

    2010-01-01

    The aim of this project is to identify a suitable site for radioactive waste repository in Pahang using remote sensing and geographical information system (GIS) technologies. There are ten parameters considered in the analysis, which divided into Selection Criteria and Exclusion Criteria. The Selection Criteria parameters consists of land use, rainfall, lineament, slope, groundwater potential and elevation while Exclusion Criteria parameters consist of urban, protected land and island. Furthermore, all parameters were integrated, given weight age and ranked for site selection evaluation in GIS environment. At the first place, about twelve sites have been identified as suitable sites for radioactive waste repository throughout the study area. These sites were further analysed by ground checking on the physical setting including geological, drainage, and population density in order to finalise three most suitable sites for radioactive waste repository. (author)

  4. 40 CFR 1400.8 - Access to off-site consequence analysis information by Federal government officials.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Access to off-site consequence... MANAGEMENT PROGRAMS UNDER THE CLEAN AIR ACT SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Access to Off-Site Consequence Analysis...

  5. 40 CFR 1400.3 - Public access to paper copies of off-site consequence analysis information.

    Science.gov (United States)

    2010-07-01

    ...-site consequence analysis information. 1400.3 Section 1400.3 Protection of Environment ENVIRONMENTAL... PROGRAMS UNDER THE CLEAN AIR ACT SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Public Access § 1400.3 Public access to...

  6. Incorporating linguistic, probabilistic, and possibilistic information in a risk-based approach for ranking contaminated sites.

    Science.gov (United States)

    Zhang, Kejiang; Achari, Gopal; Pei, Yuansheng

    2010-10-01

    Different types of uncertain information-linguistic, probabilistic, and possibilistic-exist in site characterization. Their representation and propagation significantly influence the management of contaminated sites. In the absence of a framework with which to properly represent and integrate these quantitative and qualitative inputs together, decision makers cannot fully take advantage of the available and necessary information to identify all the plausible alternatives. A systematic methodology was developed in the present work to incorporate linguistic, probabilistic, and possibilistic information into the Preference Ranking Organization METHod for Enrichment Evaluation (PROMETHEE), a subgroup of Multi-Criteria Decision Analysis (MCDA) methods for ranking contaminated sites. The identification of criteria based on the paradigm of comparative risk assessment provides a rationale for risk-based prioritization. Uncertain linguistic, probabilistic, and possibilistic information identified in characterizing contaminated sites can be properly represented as numerical values, intervals, probability distributions, and fuzzy sets or possibility distributions, and linguistic variables according to their nature. These different kinds of representation are first transformed into a 2-tuple linguistic representation domain. The propagation of hybrid uncertainties is then carried out in the same domain. This methodology can use the original site information directly as much as possible. The case study shows that this systematic methodology provides more reasonable results. © 2010 SETAC.

  7. Avaliação das informações sobre rinite alérgica em sites brasileiros na rede mundial de computadores (Internet Evaluation of Brazilian web site information on allergic rhinitis

    Directory of Open Access Journals (Sweden)

    Leonardo Victor España Rueda Silva

    2005-10-01

    , effecting more than 10% of the general population, leading to decrease in quality of life. STUDY DESIGN: review. MATERIAL AND METHOD: We performed the evaluation of 173 Brazilian web sites, which were obtained from four search engines (Google, Yahoo, AltaVista and Radar Uol. The web sites were evaluated according to the Manual of Ethical Principles, Regional Council of Medicine of the state of Sao Paulo (CREMESP, regarding transparency, honesty, quality, privacy, medical ethics, informed consent, responsibility and origin. RESULTS: Among the analyzed web sites, 149 (86.1% were not in accordance with the Manual of Ethical Principles of Regional Council of Medicine of the state of Sao Paulo (CREMESP. According to the analyzed items, the irregularities that were found were quality (84.4%, privacy (46.2%, honesty (18.5%, informed consent (15.6%, responsibility and origin (13.9%, transparency (12.1%, medical ethics (2.3%. There was inaccurate information in 24.3% of the analyzed sites. CONCLUSIONS: The majority of the websites regarding allergic rhinitis are not in accordance with the ethical principles of CREMESP. In general, the quality of a great part of the Brazilian web sites that address "allergic rhinitis", and the quality of the information disseminated by them, are insufficient to satisfy doctors and patients.

  8. Information report on nuclear safety and radiation protection of the Tricastin AREVA site - Issue 2012

    International Nuclear Information System (INIS)

    2013-06-01

    Published in compliance with the French code of the environment, this report first presents different aspects of the Areva's Tricastin site which comprises five basic nuclear installations or INBs, and seven ICPE (installation classified for the protection of the environment). The activities are dedicated to uranium conversion, uranium enrichment, uranium chemistry, industrial services, and fuel manufacturing. The report presents this important industrial site, describes the various measures regarding nuclear safety and radiation protection, reports nuclear events which occurred on this site and had to be declared, reports the management of releases by this site and the control of the environment. The next part addresses the management of the various wastes produced by the different installations present on this site. The management of other impacts is also reported. The last chapter reviews the actions undertaken in the field of transparency and information

  9. High-level radioactive waste disposal: Key geochemical issues and information needs for site characterization

    International Nuclear Information System (INIS)

    Brooks, D.J.; Bembia, P.J.; Bradbury, J.W.; Jackson, K.C.; Kelly, W.R.; Kovach, L.A.; Mo, T.; Tesoriero, J.A.

    1986-01-01

    Geochemistry plays a key role in determining the potential of a high-level radioactive waste disposal site for long-term radionuclide containment and isolation. The Nuclear Regulatory Commission (NRC) has developed a set of issues and information needs important for characterizing geochemistry at the potential sites being investigated by the Department of Energy Basalt Waste Isolation Project, Nevada Nuclear Waste Storage Investigations project, and Salt Repository Project. The NRC site issues and information needs consider (1) the geochemical environment of the repository, (2) changes to the initial geochemical environment caused by construction and waste emplacement, and (3) interactions that affect the transport of waste radionuclides to the accessible environment. The development of these issues and information needs supports the ongoing effort of the NRC to identify and address areas of geochemical data uncertainty during prelicensing interactions

  10. INFORMATION FOR THE USERS OF THE SELF-SERVICE STORES ON THE MEYRIN & PREVESSIN SITES

    CERN Multimedia

    Logistics Group

    2001-01-01

    In accordance with the Management Board's decision to rationalise the two self-service stores on the Meyrin and Prévessin sites, the users of these stores are hereby informed of the new arrangements. As of 2nd July 2001, the self-service stores will open on a half-time basis, i.e.: MEYRIN SITE SELF-SERVICE STORE (BUILDING 113) 9.00 a.m. to 12.00 midday PREVESSIN SITE SELF-SERVICE STORE (BUILDING 904) 2.30 p.m. to 4.30 p.m.

  11. INFORMATION FOR THE USERS OF THE SELF-SERVICES STORES ON THE MEYRIN AND PREVESSIN SITES

    CERN Multimedia

    Logistics Group

    2001-01-01

    In accordance with the Management Board's decision to rationalise the two self-service stores on the Meyrin and Prévessin sites, the users of these stores are hereby informed of the new arrangements. As of 2nd July 2001, the self-service stores will open on a half-time basis, i.e.: MEYRIN SITE SELF-SERVICE STORE (BUILDING 113) 9.00 a.m. to 12.00 midday PREVESSIN SITE SELF-SERVICE STORE (BUILDING 904) 2.30 p.m. to 4.30 p.m.

  12. ANL site response for the DOE FY1994 information resources management long-range plan

    Energy Technology Data Exchange (ETDEWEB)

    Boxberger, L.M.

    1992-03-01

    Argonne National Laboratory's ANL Site Response for the DOE FY1994 Information Resources Management (IRM) Long-Range Plan (ANL/TM 500) is one of many contributions to the DOE information resources management long-range planning process and, as such, is an integral part of the DOE policy and program planning system. The Laboratory has constructed this response according to instructions in a Call issued in September 1991 by the DOE Office of IRM Policy, Plans and Oversight. As one of a continuing series, this Site Response is an update and extension of the Laboratory's previous submissions. The response contains both narrative and tabular material. It covers an eight-year period consisting of the base year (FY1991), the current year (FY1992), the budget year (FY1993), the plan year (FY1994), and the out years (FY1995-FY1998). This Site Response was compiled by Argonne National Laboratory's Computing and Telecommunications Division (CTD), which has the responsibility to provide leadership in optimizing computing and information services and disseminating computer-related technologies throughout the Laboratory. The Site Response consists of 5 parts: (1) a site overview, describes the ANL mission, overall organization structure, the strategic approach to meet information resource needs, the planning process, major issues and points of contact. (2) a software plan for DOE contractors, Part 2B, Software Plan FMS plan for DOE organizations, (3) computing resources telecommunications, (4) telecommunications, (5) printing and publishing.

  13. ANL site response for the DOE FY1994 information resources management long-range plan

    Energy Technology Data Exchange (ETDEWEB)

    Boxberger, L.M.

    1992-03-01

    Argonne National Laboratory`s ANL Site Response for the DOE FY1994 Information Resources Management (IRM) Long-Range Plan (ANL/TM 500) is one of many contributions to the DOE information resources management long-range planning process and, as such, is an integral part of the DOE policy and program planning system. The Laboratory has constructed this response according to instructions in a Call issued in September 1991 by the DOE Office of IRM Policy, Plans and Oversight. As one of a continuing series, this Site Response is an update and extension of the Laboratory`s previous submissions. The response contains both narrative and tabular material. It covers an eight-year period consisting of the base year (FY1991), the current year (FY1992), the budget year (FY1993), the plan year (FY1994), and the out years (FY1995-FY1998). This Site Response was compiled by Argonne National Laboratory`s Computing and Telecommunications Division (CTD), which has the responsibility to provide leadership in optimizing computing and information services and disseminating computer-related technologies throughout the Laboratory. The Site Response consists of 5 parts: (1) a site overview, describes the ANL mission, overall organization structure, the strategic approach to meet information resource needs, the planning process, major issues and points of contact. (2) a software plan for DOE contractors, Part 2B, ``Software Plan FMS plan for DOE organizations, (3) computing resources telecommunications, (4) telecommunications, (5) printing and publishing.

  14. Geographic Information System Tools for Management of US DOE Sites - 13489

    International Nuclear Information System (INIS)

    Carpenter, Cliff; Pilz, Elaine; Pawel, Steve

    2013-01-01

    The DOE Office of Legacy Management (LM) uses a variety of GIS tools to support long-term surveillance and maintenance (LTS and M) activities at DOE closure sites. These geo-spatial applications provide access to data both for external public viewing and for internal analysis and decision making. LM uses a custom geo-spatial application called geo-spatial Environmental Mapping System (GEMS) that draws validated information from a database of 4.6 million analytical results and 232,000 water level measurements for 58 LTS and M sites. These data were collected from transferred sites over a period of 40 years. The database is used to capture and store historical environmental information such as analytical chemistry data, groundwater depths and elevations, well logs, well construction data, geo-referenced boundaries, site physical features, and sampling locations from LTS and M sites. Stakeholders, regulators, and project personnel can use this Web-based application and data to display information in several forms, such as a tabular report, a graph, and a geo-spatial display, or the data can be labeled or highlighted in a map view. Institutional controls, with their LTS and M requirements and documentation, have recently been incorporated into a prototype GEMS Web page for the Weldon Spring, Missouri, Site. LM uses multiple internal GIS viewers to help ensure the future protection of human health and the environment. For example, at the Rocky Flats, Colorado, Site, LM uses a GIS application to display real property interests on authoritative maps. Another project is used to facilitate discussions at stakeholder meetings for the Rocky Flats site's Original Landfill. The Uranium Leasing Program uses multiple interactive maps that assist in ongoing monitoring and the oversight of lease-holders' activities. (authors)

  15. Geographic Information System Tools for Management of US DOE Sites - 13489

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, Cliff [U.S. Department of Energy Office of Legacy Management, 99 Research Park Road, Morgantown, WV 26505 (United States); Pilz, Elaine [S.M. Stoller Corporation, 2597 Legacy Way, Grand Junction, CO 81503 (United States); Pawel, Steve [S.M. Stoller Corporation, 10995 Hamilton-Cleves Highway, Harrison, OH 45030 (United States)

    2013-07-01

    The DOE Office of Legacy Management (LM) uses a variety of GIS tools to support long-term surveillance and maintenance (LTS and M) activities at DOE closure sites. These geo-spatial applications provide access to data both for external public viewing and for internal analysis and decision making. LM uses a custom geo-spatial application called geo-spatial Environmental Mapping System (GEMS) that draws validated information from a database of 4.6 million analytical results and 232,000 water level measurements for 58 LTS and M sites. These data were collected from transferred sites over a period of 40 years. The database is used to capture and store historical environmental information such as analytical chemistry data, groundwater depths and elevations, well logs, well construction data, geo-referenced boundaries, site physical features, and sampling locations from LTS and M sites. Stakeholders, regulators, and project personnel can use this Web-based application and data to display information in several forms, such as a tabular report, a graph, and a geo-spatial display, or the data can be labeled or highlighted in a map view. Institutional controls, with their LTS and M requirements and documentation, have recently been incorporated into a prototype GEMS Web page for the Weldon Spring, Missouri, Site. LM uses multiple internal GIS viewers to help ensure the future protection of human health and the environment. For example, at the Rocky Flats, Colorado, Site, LM uses a GIS application to display real property interests on authoritative maps. Another project is used to facilitate discussions at stakeholder meetings for the Rocky Flats site's Original Landfill. The Uranium Leasing Program uses multiple interactive maps that assist in ongoing monitoring and the oversight of lease-holders' activities. (authors)

  16. Use of reconnaissance level information for environmental assessment. [Information available from existing sources that satisfies information needs of siting and operational aspects of NPP

    Energy Technology Data Exchange (ETDEWEB)

    Foster, R.F.; Rickard, W.H.; Strand, J.A.; Warner, M.L.

    1979-11-01

    Reconnaissance level information (RLI) sufficient for comparing the environmental and socio-economic features of candidate sites for nuclear power stations and for guiding plant design, baseline surveys, and operational practices is usually available from published reports, public records, and knowledgeable individuals. Environmental concerns of special importance for site evaluation include: aquatic ecology, terrestrial ecology, land and water use, socio-economics, and institutional constraints. A scheme is suggested for using RLI to assign classifications to candidate sites based on the potential level of concern associated with the different environmental features.

  17. Nuclear wastes: vitrification and long term behaviour. Information available on Internet sites

    International Nuclear Information System (INIS)

    Macias, R.M.

    2004-01-01

    This document reports an information search on the long-term behaviour of vitrified nuclear wastes. This search has been performed on the Internet and this report presents 21 forms corresponding to the 21 relevant Internet web sites. These forms contain the name of the organization, its country, its Internet address, its language, a brief description of the available information, the concerned public (general public, scholars and students, scientific community)

  18. Information pertinent to the migration of radionuclides in ground water at the Nevada Test Site. Part 1. Review and analysis of existing information

    International Nuclear Information System (INIS)

    Borg, I.Y.; Stone, R.; Levy, H.B.; Ramspott, L.D.

    1976-01-01

    A history of NTS is given, the geologic and hydrologic setting is described, and the amount of radioactivity deposited within and near the main aquifers is estimated. The conclusions include: information currently available is insufficient to state categorically that radioactivity will never be carried off the Nevada Test Site by ground water movement; nonetheless, such a migration at levels above the maximum permissible concentration to existing wells and springs is considered unlikely; if offsite migration occurs, it will probably be from the southwestern margins of Pahute Mesa, where there is only a small chance of contaminating existing public water supplies; tritium is the most mobile radionuclide and may be the only long-lived isotope of concern. Highest priority is assigned to measurement of tritium and other radionuclides in large water samples taken from nuclear chimneys that water has re-entered after an explosion; expansion of the existing groundwater monitoring program at NTS to include wells with a higher probability of intersecting flow of contaminated water; measurement of groundwater flow velocities and other associated hydrologic parameters. High priority is assigned to production of an inventory of radionuclides deposited near NTS borders, especially beneath Pahute Mesa; determination of amounts of radioactivity deposited directly into the Lower Carbonate Aquifer; a sensitivity analysis of the many parameters that enter into transport calculations; a study of the many unplugged holes that penetrate the Tuff Aquitard; testing of the assumption that radionuclides deposited in the unsaturated zone are isolated from the saturated zone because of limited precipitation and downward movement of moisture; and determination of distribution coefficients for NTS alluvium, carbonate, and rhyolitic rocks, which are lacking or poorly represented in the literature. Twelve other recommendations of lesser priority are also given

  19. Database system of geological information for geological evaluation base of NPP sites(I)

    International Nuclear Information System (INIS)

    Lim, C. B.; Choi, K. R.; Sim, T. M.; No, M. H.; Lee, H. W.; Kim, T. K.; Lim, Y. S.; Hwang, S. K.

    2002-01-01

    This study aims to provide database system for site suitability analyses of geological information and a processing program for domestic NPP site evaluation. This database system program includes MapObject provided by ESRI and Spread 3.5 OCX, and is coded with Visual Basic language. Major functions of the systematic database program includes vector and raster farmat topographic maps, database design and application, geological symbol plot, the database search for the plotted geological symbol, and so on. The program can also be applied in analyzing not only for lineament trends but also for statistic treatment from geologically site and laboratory information and sources in digital form and algorithm, which is usually used internationally

  20. Method for detecting core malware sites related to biomedical information systems.

    Science.gov (United States)

    Kim, Dohoon; Choi, Donghee; Jin, Jonghyun

    2015-01-01

    Most advanced persistent threat attacks target web users through malicious code within landing (exploit) or distribution sites. There is an urgent need to block the affected websites. Attacks on biomedical information systems are no exception to this issue. In this paper, we present a method for locating malicious websites that attempt to attack biomedical information systems. Our approach uses malicious code crawling to rearrange websites in the order of their risk index by analyzing the centrality between malware sites and proactively eliminates the root of these sites by finding the core-hub node, thereby reducing unnecessary security policies. In particular, we dynamically estimate the risk index of the affected websites by analyzing various centrality measures and converting them into a single quantified vector. On average, the proactive elimination of core malicious websites results in an average improvement in zero-day attack detection of more than 20%.

  1. Method for Detecting Core Malware Sites Related to Biomedical Information Systems

    Directory of Open Access Journals (Sweden)

    Dohoon Kim

    2015-01-01

    Full Text Available Most advanced persistent threat attacks target web users through malicious code within landing (exploit or distribution sites. There is an urgent need to block the affected websites. Attacks on biomedical information systems are no exception to this issue. In this paper, we present a method for locating malicious websites that attempt to attack biomedical information systems. Our approach uses malicious code crawling to rearrange websites in the order of their risk index by analyzing the centrality between malware sites and proactively eliminates the root of these sites by finding the core-hub node, thereby reducing unnecessary security policies. In particular, we dynamically estimate the risk index of the affected websites by analyzing various centrality measures and converting them into a single quantified vector. On average, the proactive elimination of core malicious websites results in an average improvement in zero-day attack detection of more than 20%.

  2. College Students' Uses and Perceptions of Social Networking Sites for Health and Wellness Information

    Science.gov (United States)

    Zhang, Yan

    2012-01-01

    Introduction: This study explores college students' use of social networking sites for health and wellness information and their perceptions of this use. Method: Thirty-eight college students were interviewed. Analysis: The interview transcripts were analysed using the qualitative content analysis method. Results: Those who had experience using…

  3. 23 CFR 750.107 - Class 3 and 4 signs outside informational sites.

    Science.gov (United States)

    2010-04-01

    ... areas. (6) Not more than one such sign advertising activities being conducted as a single enterprise or... ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent... traffic not served by an informational site within 12 air miles of the advertised activity; (2) Class 4...

  4. Three types of children’s informational web sites: an inventory of design conventions

    NARCIS (Netherlands)

    Jochmann-Mannak, Hanna; Lentz, Leo; Huibers, Theo W.C.; Sanders, Ted

    2012-01-01

    "Purpose: Research on Web design conventions has an almost exclusive focus on Web design for adults. There is far less knowledge about Web design for children. For the first time, an overview is presented of the current design conventions for children's informational Web sites. Method: In this study

  5. Environmental Justice and the Spatial Distribution of Outdoor Recreation sites: an Applications of Geographic Information Systems

    Science.gov (United States)

    Michael A. Tarrant; H. Ken Cordell

    1999-01-01

    This study examines the spatial distribution of outdoor recreation sites and their proximity to census block groups (CBGs), in order to determine potential socio-economic inequities. It is framed within the context of environmental justice. Information from the Southern Appalachian Assessment database was applied to a case study of the Chattahoochee National Forest in...

  6. 40 CFR 170.232 - Knowledge of labeling and site-specific information.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Knowledge of labeling and site-specific information. 170.232 Section 170.232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS WORKER PROTECTION STANDARD Standard for Pesticide Handlers § 170.232 Knowledge...

  7. More Than Kids Stuff: Can News and Information Web Sites Mobilize Young Adults?

    Science.gov (United States)

    Lupia, Arthur; Philpot, Tasha S.

    Many young adults are not politically active. Since 1972, their participation and interest levels have declined not only in absolute terms but also relative to other voting-age groups. This paper examines how the Internet can reverse this trend. It focuses on how leading news and political information Web sites affected young adults during the…

  8. 78 FR 18576 - Agency Information Collection Activities; Comment Request; Experimental Sites Data Collection...

    Science.gov (United States)

    2013-03-27

    ... and provide the requested data in the desired format. ED is soliciting comments on the proposed... specific information/performance data for analysis of the experiments. This effort will assist the...; Comment Request; Experimental Sites Data Collection Instrument AGENCY: Department of Education (ED...

  9. The Readability of Information Literacy Content on Academic Library Web Sites

    Science.gov (United States)

    Lim, Adriene

    2010-01-01

    This article reports on a study addressing the readability of content on academic libraries' Web sites, specifically content intended to improve users' information literacy skills. Results call for recognition of readability as an evaluative component of text in order to better meet the needs of diverse user populations. (Contains 8 tables.)

  10. Bone scintigraphy in Ewing's sarcoma during and after treatment - prognostic information from the primary tumor site

    International Nuclear Information System (INIS)

    Piers, D.A.; Veenhoven, R.H.; Kamps, W.A.; Woldring, M.G.

    1988-01-01

    A bone scan can be negative in Ewing's sarcoma. The bone scan during and after treatment can give prognostic information on the primary tumor site: A persisting hot spot strongly suggests the presence of local malignancy, while a hot spot becomming negative points to local cure of Ewing's sarcoma. (orig.)

  11. Social Site Characterisation for CO2 storage operations to inform public engagement in Poland and Scotland

    Energy Technology Data Exchange (ETDEWEB)

    Brunsting, S.; Pol, M.; Mastop, J. [Energy research Centre of the Netherlands ECN, Policy Studies, Petten (Netherlands); Kaiser, M.; Zimmer, R. [UfU - Independent Institute for Environmental Issues, Berlin (Germany); Shackley, S.; Mabon, L.; Howell, R. [The University of Edinburgh - School of Geosciences, Edinburgh, Scotland (United Kingdom); Hepplewhite, F.; Loveridge, R. [Scottish Government, Edinburgh, Scotland (United Kingdom); Mazurowski, M. [PGNiG - Polskie Gornictwo Naftowe i Gazownictwo SA, Warszawa (Poland); Rybicki, C. [AGH - University of Science and Technology, Krakow (Poland)

    2013-05-01

    Public support has proven crucial to the implementation of CO2 capture and storage (CCS) demonstration projects. Whereas no method exists to guarantee local public acceptability of any project, a constructive stakeholder engagement process does increase the likelihood thereof. Social site characterisation can be used as an instrument to plan and evaluate an approach for actively engaging local stakeholders. Social site characterisation is the process of repeatedly investigating local public awareness and opinions of a specific CCS project, changes therein over time, and underlying factors shaping public opinion as a parallel activity to technical site characterization. This paper presents results from the EU FP7 SiteChar project in which social site characterisation (a.o. surveys) and public participation activities (focus conferences) were conducted by a multidisciplinary team at two prospective CCS sites in in Poland (onshore) and Scotland (offshore). Results demonstrate that social site characterization and focus conferences are powerful tools to raise public awareness about complex issues such as CCS and to initiate local discussion and planning processes with the appropriate type of information, through appropriate media, and involving all relevant stakeholders. Application and the duration of effects in real-life project settings will be discussed.

  12. Information system of forest growth and productivity by site quality type and elements of forest

    Science.gov (United States)

    Khlyustov, V.

    2012-04-01

    Information system of forest growth and productivity by site quality type and elements of forest V.K. Khlustov Head of the Forestry Department of Russian State Agrarian University named after K.A.Timiryazev doctor of agricultural sciences, professor The efficiency of forest management can be improved substantially by development and introduction of principally new models of forest growth and productivity dynamics based on regionalized site specific parameters. Therefore an innovative information system was developed. It describes the current state and gives a forecast for forest stand parameters: growth, structure, commercial and biological productivity depend on type of site quality. In contrast to existing yield tables, the new system has environmental basis: site quality type. The information system contains set of multivariate statistical models and can work at the level of individual trees or at the stand level. The system provides a graphical visualization, as well as export of the emulation results. The System is able to calculate detailed description of any forest stand based on five initial indicators: site quality type, site index, stocking, composition, and tree age by elements of the forest. The results of the model run are following parameters: average diameter and height, top height, number of trees, basal area, growing stock (total, commercial with distribution by size, firewood and residuals), live biomass (stem, bark, branches, foliage). The system also provides the distribution of mentioned above forest stand parameters by tree diameter classes. To predict the future forest stand dynamics the system require in addition the time slot only. Full set of forest parameters mention above will be provided by the System. The most conservative initial parameters (site quality type and site index) can be kept in the form of geo referenced polygons. In this case the system would need only 3 dynamic initial parameters (stocking, composition and age) to

  13. Prioritization Scheme for Proposed Road Weather Information System Sites: Montana Case Study

    Directory of Open Access Journals (Sweden)

    Ahmed Al-Kaisy

    2017-08-01

    Full Text Available A model for prioritization of new proposed environmental sensor station (ESS sites is developed and presented in this paper. The model assesses the overall merit (OM of a proposed ESS site as part of a Road Weather Information System (RWIS using weather, traffic, and safety data among other variables. The purpose of the proposed model is to help in selecting optimum sites for new ESS locations, which is important in guiding RWIS system expansion. Inputs to the OM model include weather index (WI, traffic index (TI, crash index, geographic coverage, and opportunistic factors. The WI at a proposed site is determined using multiple indicators of weather severity and variability. The crash index, another major input to the OM model, incorporates crash rate along the route and the percentage of weather-related crashes over the analysis period. The TI, in turn, reflects the amount of travel on the highway network in the area surrounding the proposed ESS site. The fourth input to the merit model accounts for the ESS existing coverage in the area where the proposed site is located, while the fifth and last input is concerned with the availability and ease of access to power and communications. Model coefficients are represented by weights that reflect the contribution of each input (variable to the OM of the ESS site. Those weights are user-specified and should be selected to reflect the agency preferences and priorities. The application of the proposed merit model on sample sites in Montana demonstrated the utility of the model in ranking candidate sites using data readily available to highway agencies.

  14. A Guide to On-line Geological Information and Publications for Use in GSHP Site Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Rafferty, K

    2000-03-01

    One of the first steps in the consideration of a GSHP system is a characterization of the site in terms of geology and groundwater availability. Information concerning aquifer (or aquifers) available at the site, their ability to produce water, depth to water, geology, depth to bedrock and the nature of the soil and rock (hydraulic and thermal properties) are key issues. This information guides the designer in the selection of the type of GSHP system to be used and in the design of the system. The ground source industry has not taken full advantage of available geological information resources in the past. This document is an effort to introduce GSHP designers to some of these information sources and the nature of the data that is available. A special emphasis has been placed on Internet based resources operated by government agencies--primarily the USGS and state geological surveys. The following section provides some background information on the maps and other information sources in general. This is followed by summaries of information available for the most active GSHP states.

  15. Position-specific prediction of methylation sites from sequence conservation based on information theory.

    Science.gov (United States)

    Shi, Yinan; Guo, Yanzhi; Hu, Yayun; Li, Menglong

    2015-07-23

    Protein methylation plays vital roles in many biological processes and has been implicated in various human diseases. To fully understand the mechanisms underlying methylation for use in drug design and work in methylation-related diseases, an initial but crucial step is to identify methylation sites. The use of high-throughput bioinformatics methods has become imperative to predict methylation sites. In this study, we developed a novel method that is based only on sequence conservation to predict protein methylation sites. Conservation difference profiles between methylated and non-methylated peptides were constructed by the information entropy (IE) in a wider neighbor interval around the methylation sites that fully incorporated all of the environmental information. Then, the distinctive neighbor residues were identified by the importance scores of information gain (IG). The most representative model was constructed by support vector machine (SVM) for Arginine and Lysine methylation, respectively. This model yielded a promising result on both the benchmark dataset and independent test set. The model was used to screen the entire human proteome, and many unknown substrates were identified. These results indicate that our method can serve as a useful supplement to elucidate the mechanism of protein methylation and facilitate hypothesis-driven experimental design and validation.

  16. MRI of congenital pituitary insufficiency

    International Nuclear Information System (INIS)

    Almeida Magalhaes, Alvaro C. de; Uehara, Karla C.; Iezzi, Denise

    1995-01-01

    We compare 1,5 T magnetic resonance (MR) image findings in 193 patients with congenital pituitary congenital insufficiency. One hundred and thirty nine of the MR studies were obtained in patients who had isolated growth hormone deficiency. Other fifth - four patients had multiple pituitary hormone deficiency. On MR images, normal anterior and posterior lobes of the pituitary glands can be clearly differentiated because the posterior lobe has a characteristic high intensity on TI-weighted images. In fifty-four patients, the high- intensity of the posterior lobe was not seen, but a similar high signal intensity was observed at the proximal stump in fifty-one patients. this high- intensity area is the newly formed ectopic posterior lobe, which also secrets anti-diuretic hormone just as the posterior lobe would. MR imaging can demonstrate the transection of the pituitary stalk and the formation of the ectopic lobe, revealing to be a useful diagnostic tool in the definition of the type of alteration in growth defects of endocrine origin. (author)

  17. Development of portal web site for fostering of risk literacy 'risk information navigator'

    International Nuclear Information System (INIS)

    Shobu, Nobuhiro; Mitsui, Seiichiro; Nakamura, Hirofumi

    2004-01-01

    Risk communication activities are important for promoting mutual understanding between local communities and Japan Nuclear Cycle Development Institutes (JNC). In addition to conventional public relation activities, the risk communication study team of JNC Tokai Works has started practical studies to promote further mutual understanding with its local communities. This paper reports the design and concept of a web site for the fostering of risk literacy, the 'Risk Information Navigator', that was developed as one of the risk communication methods, and surveys the web site from the user's perspective. (author)

  18. Web-site evaluation tools: a case study in reproductive health information.

    Science.gov (United States)

    Aslani, Azam; Pournik, Omid; Abu-Hanna, Ameen; Eslami, Saeid

    2014-01-01

    Internet forms an opportunity to inform, teach, and connect professionals and patients. However, much information on Internet is incomplete, inaccurate, or misleading, and not only in the medical domain. Because of the potential for damage from misleading and inaccurate health information, many organizations and individuals have published or implemented scoring tools for evaluating the appropriateness or quality of these resources. The objective of this study is to identify and summarize scoring tools that have evaluated web-sites providing reproductive health information in order to compare them and recommend an overarching evaluation tool. We searched Ovid MEDLINE(R) (1946 to July 2013) and OVID Embase (1980 to July 2013); and included English language studies that have evaluated the quality of websites providing reproductive health information. Studies only assessing the content of websites were excluded. We identified 5 scoring tools: 1-The HON (health on the net) Code of Conduct for medical and health Web sites, 2-Silberg scores, 3-Hogne Sandvik scale, 4-Jim Kapoun's Criteria for Evaluating Web Pages, and 5-The Health Information Technology Institute (HITI) criteria. We have compared these scales and identified 14 criteria: authorship, ownership, currency, objectivity/content, transparency/source, interactivity, privacy/ethics, financial disclosure, navigability/links, complementarity, advertising policy, design, quantity, and accessibility. We integrated these criteria and introduced a new tool with 10 criteria. Website evaluation tools differ in their evaluation criteria and there is a lack of consensus about which to use; therefore, an integrated easy to use set of criteria is needed.

  19. HANFORD SITE SOLID WASTE MANAGEMENT ENVIRONMENTAL IMPACT STATEMENT TECHNICAL INFORMATION DOCUMENT [SEC 1 THRU 4

    International Nuclear Information System (INIS)

    FRITZ, L.L.

    2004-01-01

    This Technical Information Document (TID) provides engineering data to support DOE/EIS-0286, ''Hanford Site Solid (Radioactive and Hazardous) Waste Program Environmental Impact Statement''. Assumptions and waste volumes used to calculate engineering data are also provided in this document. This chapter provides a brief description of: the Solid Waste Management Program (including a description of waste types and known characteristics of waste covered under the program), the Hanford Site (including a general discussion of the operating areas), and the alternatives analyzed. The Hanford Site Solid Waste Management Program and DOE/EIS-0286 address solid radioactive waste types generated by various activities from both onsite and offsite generators. The Environmental Restoration (ER) waste management activities are not within the scope of DOE/EIS-0286 or this TID. Activities for processing and disposal of immobilized low-activity waste (ILAW) are not within the scope of the Solid Waste Management Program and this TID

  20. Call for information on coastal energy facility siting: an analysis of responses

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    The Call for Information issued by the New Jersey Department of Environmental Protection in December 1975 consisted of an eight page questionnaire which was sent to industries, government agencies, and private organizations. Its objective was to seek the help of these groups in plans for the siting of energy facilities in the coastal zone. Potential development of oil and gas from the Baltimore Canyon region adjacent to New Jersey has made planning for energy facilities a priority issue both at the state and federal level. The Call for Information invited government and the energy industry to submit (a) suggested criteria for locating energy and energy-related facilities within the New Jersey coastal zone, (b) analyses by governmental and private agencies or groups of the need to locate energy facilities in specific sites within New Jersey's coastal zone, or in generalized portions thereof, and (c) identification of the land-use parameters, appropriate to the various types of facilities which may be proposed, now or later, for coastal siting. The findings obtained from the draft call and the final call issued seven months later are presented. The results of the industries' responses show that the electric and gas utilities gave some useful information while this was true of only a few of the oil companies. The reluctance to give informatign was perhaps aggravated by lack of clear state and federal policies. The appendices illustrate specific information on manpower, cost and facility requirements to develop oil refineries, establish a gas processing plant as well as information from the US Coast Guard and the Environmental Protection Agency. There is also a listing of the companies that bid in the August 1976 lease sale indicating which bids were accepted, a map of the offshore tracts, and a list of which companies responded to the Call for Information

  1. Westinghouse Savannah River Site Supplier Environmental Restoration and Waste Management Information Exchange Forum

    International Nuclear Information System (INIS)

    Sturm, H.F. Jr.; Hottel, R.E.; Christoper, N.

    1994-01-01

    The Savannah River Site conducted its first Supplier Information Exchange in September 1993. The intent of the conference was to inform potential suppliers of the Savannah River Sites mission and research and development program objectives in the areas of environmental restoration and waste management, and to solicit proposals for innovative research in those areas. Major areas addressed were Solid Waste, Environmental Restoration, Environmental Monitoring, Transition/Decontamination and Decommissioning, and the Savannah River Technology Center. A total of 1062 proposals were received addressing the 89 abstracts presented. This paper will describe the forum the process for solicitation, the process for proposal review and selection, and review the overall results and benefits to Savannah River

  2. Smooth Operator - Mobile Information Technology for Improved Flow at the Construction Site

    DEFF Research Database (Denmark)

    Tambo, Torben

    2010-01-01

    is used; mobility is classified as remote, local or micro. Furthermore an extensive literature study is employed along with both market screening for systems and case studies of companies adopting as well as rejecting the technology. Both within research communities, software manufacturers......Mobile information technology (IT) seems an ideal innovation to promote effectiveness of the construction process, particularly at the construction site; research has over the last 15 years focused on solutions, potentials and barriers with this field. This paper aim at the duality between research...... and industry for an updated and forward looking comprehension, and view of tendencies, of the roles and potentials of mobile IT at the construction site including potential for further research. Qualitative and interpretive methodology inspired by information systems and sociology of research and construction...

  3. Remedial Action Plan and Site Design for Stabilization of the Inactive Uranium Mill Tailings Sites at Slick Rock, Colorado: Appendix B to Attachment 3, Lithologic logs and monitor well construction information. Final report

    International Nuclear Information System (INIS)

    1995-09-01

    This volume contains lithology logs and monitor well construction information for: NC processing site; UC processing site; and Burro Canyon disposal site. This information pertains to the ground water hydrology investigations which is attachment 3 of this series of reports

  4. Creation of integrated information model of 'Ukryttya' object premises and industrial site conditions to support works

    International Nuclear Information System (INIS)

    Postil, S.D.; Ermolenko, A.I.; Ivanov, V.V.; Kotlyarov, V.T.

    2004-01-01

    Data integration is made using standard AutoCAD utility and special software developed in Visual Basic for Application language. Mutual transfer is realized between the applications prepared in Access and AutoCAD with displaying the submitted information. The work demonstrates a possibility to apply integrated information model for investigating radiation field's change and analysis regularities in premises and on industrial site area, development and visualization, with the use of computer animation means, of movement routes, displaying of emergency situations being forecast with the help of computer graphics means, integration of raster display of structures and vector computer model of objects

  5. Burial sites, informal rights and lost kingdoms: the contesting of land claims in Mpumalanga, South Africa

    OpenAIRE

    Deborah James

    2009-01-01

    In the new South Africa, the promise of land restitution raised millennial-style expectations amongst dispossessed and dispersed former landholders. Partly prompted by emerging policy discourses, iconic tropes of localised cultural experience such as grave sites, initiation lodges and cattle byres have acquired new significance: they became verifiable evidence of effective possession of – because proving what the Land Claims Commission calls ‘informal rights’ in – land. They thus became groun...

  6. Information on web-site of the State protection of nature

    International Nuclear Information System (INIS)

    Rajtar, R.

    2005-01-01

    Statna ochrana prirody SR (SOP SR - State protection of nature of the Slovak Republic) is professional organisation with all-Slovak operation, which operation is aimed on provision of professional activities for service of state administration in protection of nature and landscape. Structure of the SOP SR, their operation and information presented on the web site of the SOP SR (www.sopsr.sk) are described

  7. Small stones sets Web site apart. Froedtert Hospital updates provide valuable healthcare information.

    Science.gov (United States)

    Rees, Tom

    2002-01-01

    Froedtert & Medical College, an academic medical center, has adopted a proactive approach to providing consumers with reliable sources of information. The Milwaukee institution has redesigned its Web site, which first opened in 1995. The new version has simplified the navigation process and added new content. Small Stones, a health resource center, also a brick-and-mortar shop, went online Feb. 1. Online bill paying was launched in May. Pharmacy refill functions are expected to be online this summer.

  8. Discovery and validation of information theory-based transcription factor and cofactor binding site motifs.

    Science.gov (United States)

    Lu, Ruipeng; Mucaki, Eliseos J; Rogan, Peter K

    2017-03-17

    Data from ChIP-seq experiments can derive the genome-wide binding specificities of transcription factors (TFs) and other regulatory proteins. We analyzed 765 ENCODE ChIP-seq peak datasets of 207 human TFs with a novel motif discovery pipeline based on recursive, thresholded entropy minimization. This approach, while obviating the need to compensate for skewed nucleotide composition, distinguishes true binding motifs from noise, quantifies the strengths of individual binding sites based on computed affinity and detects adjacent cofactor binding sites that coordinate with the targets of primary, immunoprecipitated TFs. We obtained contiguous and bipartite information theory-based position weight matrices (iPWMs) for 93 sequence-specific TFs, discovered 23 cofactor motifs for 127 TFs and revealed six high-confidence novel motifs. The reliability and accuracy of these iPWMs were determined via four independent validation methods, including the detection of experimentally proven binding sites, explanation of effects of characterized SNPs, comparison with previously published motifs and statistical analyses. We also predict previously unreported TF coregulatory interactions (e.g. TF complexes). These iPWMs constitute a powerful tool for predicting the effects of sequence variants in known binding sites, performing mutation analysis on regulatory SNPs and predicting previously unrecognized binding sites and target genes. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  9. Application of geographical information system in disposal site selection for hazardous wastes.

    Science.gov (United States)

    Rezaeimahmoudi, Mehdi; Esmaeli, Abdolreza; Gharegozlu, Alireza; Shabanian, Hassan; Rokni, Ladan

    2014-01-01

    The aim of this study was to provide a scientific method based on Geographical Information System (GIS) regarding all sustainable development measures to locate a proper landfill for disposal of hazardous wastes, especially industrial (radioactive) wastes. Seven effective factors for determining hazardous waste landfill were applied in Qom Province, central Iran. These criteria included water, slope, population centers, roads, fault, protected areas and geology. The Analysis Hierarchical Process (AHP) model based on pair comparison was used. First, the weight of each factor was determined by experts; afterwards each layer of maps entered to ARC GIS and with special weight multiplied together, finally the best suitable site was introduced. The most suitable sites for burial were in northwest and west of Qom Province and eventually five zones were introduced as the sample sites. GIs and AHP model is introduced as the technical, useful and accelerator tool for disposal site selection. Furthermore it is determined that geological factor is the most effective layer for site selection. It is suggested that geological conditions should be considered primarily then other factors are taken into consideration.

  10. Combining geographic information system, multicriteria evaluation techniques and fuzzy logic in siting MSW landfills

    Science.gov (United States)

    Gemitzi, Alexandra; Tsihrintzis, Vassilios A.; Voudrias, Evangelos; Petalas, Christos; Stravodimos, George

    2007-01-01

    This study presents a methodology for siting municipal solid waste landfills, coupling geographic information systems (GIS), fuzzy logic, and multicriteria evaluation techniques. Both exclusionary and non-exclusionary criteria are used. Factors, i.e., non-exclusionary criteria, are divided in two distinct groups which do not have the same level of trade off. The first group comprises factors related to the physical environment, which cannot be expressed in terms of monetary cost and, therefore, they do not easily trade off. The second group includes those factors related to human activities, i.e., socioeconomic factors, which can be expressed as financial cost, thus showing a high level of trade off. GIS are used for geographic data acquisition and processing. The analytical hierarchy process (AHP) is the multicriteria evaluation technique used, enhanced with fuzzy factor standardization. Besides assigning weights to factors through the AHP, control over the level of risk and trade off in the siting process is achieved through a second set of weights, i.e., order weights, applied to factors in each factor group, on a pixel-by-pixel basis, thus taking into account the local site characteristics. The method has been applied to Evros prefecture (NE Greece), an area of approximately 4,000 km2. The siting methodology results in two intermediate suitability maps, one related to environmental and the other to socioeconomic criteria. Combination of the two intermediate maps results in the final composite suitability map for landfill siting.

  11. Annotating the protein-RNA interaction sites in proteins using evolutionary information and protein backbone structure.

    Science.gov (United States)

    Li, Tao; Li, Qian-Zhong

    2012-11-07

    RNA-protein interactions play important roles in various biological processes. The precise detection of RNA-protein interaction sites is very important for understanding essential biological processes and annotating the function of the proteins. In this study, based on various features from amino acid sequence and structure, including evolutionary information, solvent accessible surface area and torsion angles (φ, ψ) in the backbone structure of the polypeptide chain, a computational method for predicting RNA-binding sites in proteins is proposed. When the method is applied to predict RNA-binding sites in three datasets: RBP86 containing 86 protein chains, RBP107 containing 107 proteins chains and RBP109 containing 109 proteins chains, better sensitivities and specificities are obtained compared to previously published methods in five-fold cross-validation tests. In order to make further examination for the efficiency of our method, the RBP107 dataset is used as training set, RBP86 and RBP109 datasets are used as the independent test sets. In addition, as examples of our prediction, RNA-binding sites in a few proteins are presented. The annotated results are consistent with the PDB annotation. These results show that our method is useful for annotating RNA binding sites of novel proteins.

  12. Sharing for Health: A Study of Chinese Adolescents' Experiences and Perspectives on Using Social Network Sites to Share Health Information.

    Science.gov (United States)

    Zhang, Ni; Teti, Michele; Stanfield, Kellie; Campo, Shelly

    2017-07-01

    This exploratory qualitative study examines Chinese adolescents' health information sharing habits on social network sites. Ten focus group meetings with 76 adolescents, ages 12 to 17 years, were conducted at community-based organizations in Chicago's Chinatown. The research team transcribed the recording and analyzed the transcripts using ATLAS.ti. Chinese adolescents are using different social network sites for various topics of health information including food, physical activity, and so on. Adolescents would share useful and/or interesting health information. Many adolescents raised credibility concerns regarding health information and suggested evaluating the information based on self-experience or intuition, word-of-mouth, or information online. The findings shed lights on future intervention using social network sites to promote health among Chinese adolescents in the United States. Future interventions should provide adolescents with interesting and culturally sensitive health information and educate them to critically evaluate health information on social network sites.

  13. Glottal insufficiency with aspiration risk in dysphagia.

    Science.gov (United States)

    Giraldez-Rodriguez, Laureano A; Johns, Michael

    2013-12-01

    Glottal closure is an important part of the mechanism that protects the airway during the normal swallow. Glottal insufficiency disrupts glottal closure and therefore puts patients at risk of aspiration. Treatment of glottal insufficiency can be classified as surgical or nonsurgical. The objective of treating glottal insufficiency is to avoid aspiration or penetration of secretions or food into the airway. Nonsurgical treatment consists of swallowing maneuvers and other measures. Surgical treatment of glottal insufficiency includes injection laryngoplasty, medialization thyroplasty with or without arytenoid adduction or with arytenopexy and cricothyroid subluxation, hypopharyngoplasty, cricopharynx muscle dilation, and cricopharynx myotomy. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. 3D Information System of Historical Site – Proposal and Realisation of a Functional Prototype

    Directory of Open Access Journals (Sweden)

    J. Hodač

    2005-01-01

    Full Text Available The development of methods for 3D data acquisition, together with progress in information technologies raises the question of creating and using 3D models and 3D information systems (IS of historical sites and buildings. This paper presents the current state of the “Live Theatre” project. The theme of the project is the proposal and realisation of a 3D IS of the baroque theatre at Eeský Krumlov castle (UNESCO site.The project is divided into three main stages – creation of a 3D model, proposal of a conception for a 3D IS, and realisation of a functional prototype. 3D data was acquired by means of photogrammetric and surveying methods. An accurate 3D model (photo-realistic, textured was built up with MicroStation CAD system. The proposal of a conception of a 3D IS was the main outcome of the author’s dissertation. The essential feature of the proposed conception is the creation of subsystems targeted on three spheres – management, research and presentation of the site. The functionality of each subsystem is connected with its related sphere; however, each subsystem uses the same database. The present stage of the project involves making a functional prototype (with sample data. During this stage we are working on several basic technological topics. At present we are concerned with 3D data, its formats, format conversions (e.g. DGN _ VRML and its connection to other types of data. After that, we will be seeking a convenient technical solution based on network technologies (Internet and an appropriate layout for the data (database. The project is being carried out in close co-operation with the administration of the castle and some other partners. This stage of the project will be completed in December 2005.A functional prototype and the information acquired by testing it will form the basis for the final proposal of a complex IS of a historical site. The final proposal and appropriate technology will be the outcome of the project. The

  15. New York state information handbook formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying our the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New York. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  16. New Mexico state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New Mexico. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  17. New York state information handbook: formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New York. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  18. New Mexico state information handbook: formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New Mexico. It contains a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  19. Integrating geographical information and augmented reality techniques for mobile escape guidelines on nuclear accident sites

    International Nuclear Information System (INIS)

    Tsai, Ming-Kuan; Lee, Yung-Ching; Lu, Chung-Hsin; Chen, Mei-Hsin; Chou, Tien-Yin; Yau, Nie-Jia

    2012-01-01

    During nuclear accidents, when radioactive materials spread into the environment, the people in the affected areas should evacuate immediately. However, few information systems are available regarding escape guidelines for nuclear accidents. Therefore, this study constructs escape guidelines on mobile phones. This application is called Mobile Escape Guidelines (MEG) and adopts two techniques. One technique is the geographical information that offers multiple representations; the other is the augmented reality that provides semi-realistic information services. When this study tested the mobile escape guidelines, the results showed that this application was capable of identifying the correct locations of users, showing the escape routes, filtering geographical layers, and rapidly generating the relief reports. Users could evacuate from nuclear accident sites easily, even without relief personnel, since using slim devices to access the mobile escape guidelines is convenient. Overall, this study is a useful reference for a nuclear accident emergency response.

  20. Integrating geographical information and augmented reality techniques for mobile escape guidelines on nuclear accident sites.

    Science.gov (United States)

    Tsai, Ming-Kuan; Lee, Yung-Ching; Lu, Chung-Hsin; Chen, Mei-Hsin; Chou, Tien-Yin; Yau, Nie-Jia

    2012-07-01

    During nuclear accidents, when radioactive materials spread into the environment, the people in the affected areas should evacuate immediately. However, few information systems are available regarding escape guidelines for nuclear accidents. Therefore, this study constructs escape guidelines on mobile phones. This application is called Mobile Escape Guidelines (MEG) and adopts two techniques. One technique is the geographical information that offers multiple representations; the other is the augmented reality that provides semi-realistic information services. When this study tested the mobile escape guidelines, the results showed that this application was capable of identifying the correct locations of users, showing the escape routes, filtering geographical layers, and rapidly generating the relief reports. Users could evacuate from nuclear accident sites easily, even without relief personnel, since using slim devices to access the mobile escape guidelines is convenient. Overall, this study is a useful reference for a nuclear accident emergency response. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. New York state information handbook formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying our the Formerly Utilized Sites Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New York. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  2. Early intervention and management of adrenal insufficiency in children.

    LENUS (Irish Health Repository)

    Moloney, Sinéad

    2012-09-01

    The endocrine disorder adrenal insufficiency includes inadequate production of the steroid hormone cortisol. This results in poor physiological responses to illness, trauma or other stressors and risk of adrenal crisis. Management is based on administration of hydrocortisone. It is important to avoid under- or over-treatment and increase the dosage during times of physiological stress. To reduce morbidity, hospital admissions and mortality, the education and empowerment of parents and carers, and prompt intervention when necessary are essential. A steroid therapy card for adrenal insufficiency containing personal information on a patient\\'s condition was developed for use by families and their specialist centres.

  3. Hypothalamic functions in patients with pituitary insufficiency

    NARCIS (Netherlands)

    Borgers, A.J.F.

    2013-01-01

    The main objective of this thesis is to increase our understanding of hypothalamic (dys)function in patients with pituitary insufficiency. This goal is driven by the clinical experience of persisting symptoms in patients adequately treated for pituitary insufficiency. We focus primarily on patients

  4. Documentation information for peer group review report site suitability criteria study

    International Nuclear Information System (INIS)

    1977-10-01

    This report presents documentation of the geotechnical input data provided by Golder Associates, Inc. (GAI) for the Cycle II repository model analysis. Information relating to the proposed uncertainty analysis and several appropriate comments pertinent to the overall site suitability study are also included. GAI was responsible for developing descriptors and coefficients for the TASC model hydrologic analog; permeability and porosity values for the geologic formations (excepting salt); occurrence and properties of the bore hole seals, backfill, and mine fracture zones; and properties of fracture zones associated with faults. All data are presented with a preferred value and maximum credible range. These values relate to a generic repository in a sedimentary basin and not a specific site. 13 figures, 6 tables

  5. Information report on nuclear safety and radiation protection of La Hague AREVA site. Issue 2014

    International Nuclear Information System (INIS)

    2013-01-01

    Published in compliance with the French code of the environment, this report first presents the Areva's La Hague site which comprises several basic nuclear installations (INB), is dedicated to several activities related to the nuclear fuel cycle, is submitted to a constraining legal and regulatory framework, and implements a policy for a sustainable development and continuous progress. The document describes the various measures regarding nuclear safety and radiation protection, reports nuclear events which are classified according to the INES scale and occurred and had to be declared in 2014, describes the management of effluents by the different installations present on this site and the control of the environment. It addresses the waste management and the management of other impacts. It gives an overview of actions undertaken regarding information and transparency. Recommendations of the CHSCT are reported

  6. Information report on nuclear safety and radiation protection of La Hague AREVA site. Issue 2013

    International Nuclear Information System (INIS)

    2014-01-01

    Published in compliance with the French code of the environment, this report first presents the Areva's La Hague site which comprises several basic nuclear installations (INB), is dedicated to several activities related to the nuclear fuel cycle, is submitted to a constraining legal and regulatory framework, and implements a policy for a sustainable development and continuous progress. The document describes the various measures regarding nuclear safety and radiation protection, reports nuclear events which are classified according to the INES scale and occurred and had to be declared in 2013, describes the management of effluents by the different installations present on this site and the control of the environment. It addresses the waste management and the management of other impacts. It gives an overview of actions undertaken regarding information and transparency. Recommendations of the CHSCT are reported

  7. Graphics-based site information management at Hanford TRU burial grounds

    International Nuclear Information System (INIS)

    Rod, S.R.

    1992-01-01

    The objective of the project described in this paper is to demonstrate the use of integrated computer graphics and data base techniques in managing nuclear waste facilities. The graphics-based site information management system (SIMS) combines a three-dimensional graphic model of the facility with databases which describe the facility's components and waste inventory. The SIMS can create graphic visualizations of any site data. The SIMS described here is being used by Westinghouse Hanford Company (WHC) as part of its transuranic (TRU) waste retrieval program at the Hanford Reservation. It is being used to manage an inventory of over 38,000 containers, to validate records, and to help visualize conceptual designs of waste retrieval operations

  8. Information report on nuclear safety and radiation protection of the La Hague AREVA site- Issue 2012

    International Nuclear Information System (INIS)

    2013-06-01

    Published in compliance with the French code of the environment, this report first presents the Areva's La Hague site which comprises several basis nuclear installations (INB), is dedicated to several activities related to the nuclear fuel cycle, is submitted to a constraining legal and regulatory framework, and implements a policy for a sustainable development and continuous progress. The document describes the various measures regarding nuclear safety and radiation protection, reports nuclear events which are classified according to the INES scale and occurred and had to be declared in 2012, describes the management of effluents by the different installations present on this site and the control of the environment. It addresses the waste management and the management of other impacts. It gives an overview of actions undertaken regarding information and transparency. Recommendations of the CHSCT are reported

  9. A New Information Architecture, Web Site and Services for the CMS Experiment

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    The age and size of the CMS collaboration at the LHC means it now has many hundreds of inhomogeneous web sites and services and more than 100,000 documents. We describe a major initiative to create a single coherent CMS internal and public web site. This uses the Drupal web Content Management System (now supported by CERN/IT) on top of a standard LAMP stack (Linux, Apache, MySQL, and php/perl). The new navigation, content and search services are coherently integrated with numerous existing CERN services (CDS, EDMS, Indico, phonebook, Twiki) as well as many CMS internal Web services. We describe the information architecture; the system design, implementation and monitoring; the document and content database; security aspects; and our deployment strategy which ensured continual smooth operation of all systems at all times.

  10. Graphics-based site information management at Hanford TRU burial grounds

    International Nuclear Information System (INIS)

    Rod, S.R.

    1992-04-01

    The objective of the project described in this paper is to demonstrate the use of integrated computer graphics and database techniques in managing nuclear waste facilities. The graphics-based site information management system (SIMS) combines a three- dimensional graphic model of the facility with databases which describe the facility's components and waste inventory. The SIMS can create graphic visualization of any site data. The SIMS described here is being used by Westinghouse Hanford Company (WHC) as part of its transuranic (TRU) waste retrieval program at the Hanford Reservation. It is being used to manage an inventory of over 38,000 containers, to validate records, and to help visualize conceptual designs of waste retrieval operations

  11. Optimal glucocorticoid replacement in adrenal insufficiency.

    Science.gov (United States)

    Øksnes, Marianne; Ross, Richard; Løvås, Kristian

    2015-01-01

    Adrenal insufficiency (glucocorticoid deficiency) comprises a group of rare diseases, including primary adrenal insufficiency, secondary adrenal insufficiency and congenital adrenal hyperplasia. Lifesaving glucocorticoid therapy was introduced over 60 years ago, but since then a number of advances in treatment have taken place. Specifically, little is known about short- and long-term treatment effects, and morbidity and mortality. Over the past decade, systematic cohort and registry studies have described reduced health-related quality of life, an unfavourable metabolic profile and increased mortality in patients with adrenal insufficiency, which may relate to unphysiological glucocorticoid replacement. This has led to the development of new modes of replacement that aim to mimic normal glucocorticoid physiology. Here, evidence for the inadequacy of conventional glucocorticoid therapy and recent developments in treatment are reviewed, with an emphasis on primary adrenal insufficiency. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. New Jersey state information handbook: Formerly Utilized Sites Remedial Action Program

    International Nuclear Information System (INIS)

    1980-01-01

    Under the implied authority of the Atomic Energy Act of 1954, as amended, radiological surveys and research work has been conducted to determine radiological conditions at former MED/AEC sites. As of this time, 31 sites in 13 states have been identified that require or may require remedial action. This volume is one of a series produced under contract with DOE, Office of Nuclear Waste Management, by POLITECH CORPORATION to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of New Jersey. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations. The loose-leaf format used in these volumes will allow the material to be updated periodically as the Remedial Action Program progresses

  13. In the patient's best interest: appraising social network site information for surrogate decision making.

    Science.gov (United States)

    Siddiqui, Shahla; Chuan, Voo Teck

    2018-06-28

    This paper will discuss why and how social network sites ought to be used in surrogate decision making (SDM), with focus on a context like Singapore in which substituted judgment is incorporated as part of best interest assessment for SDM, as guided by the Code of Practice for making decisions for those lacking mental capacity under the Mental Capacity Act (2008). Specifically, the paper will argue that the Code of Practice already supports an ethical obligation, as part of a patient-centred care approach, to look for and appraise social network site (SNS) as a source of information for best interest decision making. As an important preliminary, the paper will draw on Berg's arguments to support the use of SNS information as a resource for SDM. It will also supplement her account for how SNS information ought to be weighed against or considered alongside other evidence of patient preference or wishes, such as advance directives and anecdotal accounts by relatives. © Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ.

  14. New Jersey state information handbook: Formerly Utilized Sites Remedial Action Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-10-31

    Under the implied authority of the Atomic Energy Act of 1954, as amended, radiological surveys and research work has been conducted to determine radiological conditions at former MED/AEC sites. As of this time, 31 sites in 13 states have been identified that require or may require remedial action. This volume is one of a series produced under contract with DOE, Office of Nuclear Waste Management, by POLITECH CORPORATION to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Remedial Action Program. This Information Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the state of New Jersey. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations. The loose-leaf format used in these volumes will allow the material to be updated periodically as the Remedial Action Program progresses.

  15. FLUXNET. Database of fluxes, site characteristics, and flux-community information

    Energy Technology Data Exchange (ETDEWEB)

    Olson, R. J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Holladay, S. K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Cook, R. B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Falge, E. [Univ. Bayreuth, Bayreuth (Germany); Baldocchi, D. [Univ. of California, Berkeley, CA (United States); Gu, L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2004-02-28

    FLUXNET is a “network of regional networks” created by international scientists to coordinate regional and global analysis of observations from micrometeorological tower sites. The flux tower sites use eddy covariance methods to measure the exchanges of carbon dioxide (CO2), water vapor, and energy between terrestrial ecosystems and the atmosphere. FLUXNET’S goals are to aid in understanding the mechanisms controlling the exchanges of CO2, water vapor, and energy across a range of time (0.5 hours to annual periods) and space scales. FLUXNET provides an infrastructure for the synthesis and analysis of world-wide, long-term flux data compiled from various regional flux networks. Information compiled by the FLUXNET project is being used to validate remote sensing products associated with the National Aeronautics and Space Administration (NASA) Terra and Aqua satellites. FLUXNET provides access to ground information for validating estimates of net primary productivity, and energy absorption that are being generated by the Moderate Resolution Imaging Spectroradiometer (MODIS) sensors. In addition, this information is also used to develop and validate ecosystem models.

  16. Prediction of glutathionylation sites in proteins using minimal sequence information and their experimental validation.

    Science.gov (United States)

    Pal, Debojyoti; Sharma, Deepak; Kumar, Mukesh; Sandur, Santosh K

    2016-09-01

    S-glutathionylation of proteins plays an important role in various biological processes and is known to be protective modification during oxidative stress. Since, experimental detection of S-glutathionylation is labor intensive and time consuming, bioinformatics based approach is a viable alternative. Available methods require relatively longer sequence information, which may prevent prediction if sequence information is incomplete. Here, we present a model to predict glutathionylation sites from pentapeptide sequences. It is based upon differential association of amino acids with glutathionylated and non-glutathionylated cysteines from a database of experimentally verified sequences. This data was used to calculate position dependent F-scores, which measure how a particular amino acid at a particular position may affect the likelihood of glutathionylation event. Glutathionylation-score (G-score), indicating propensity of a sequence to undergo glutathionylation, was calculated using position-dependent F-scores for each amino-acid. Cut-off values were used for prediction. Our model returned an accuracy of 58% with Matthew's correlation-coefficient (MCC) value of 0.165. On an independent dataset, our model outperformed the currently available model, in spite of needing much less sequence information. Pentapeptide motifs having high abundance among glutathionylated proteins were identified. A list of potential glutathionylation hotspot sequences were obtained by assigning G-scores and subsequent Protein-BLAST analysis revealed a total of 254 putative glutathionable proteins, a number of which were already known to be glutathionylated. Our model predicted glutathionylation sites in 93.93% of experimentally verified glutathionylated proteins. Outcome of this study may assist in discovering novel glutathionylation sites and finding candidate proteins for glutathionylation.

  17. Background Information for the Nevada National Security Site Integrated Sampling Plan, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Farnham, Irene; Marutzky, Sam

    2014-12-01

    This document describes the process followed to develop the Nevada National Security Site (NNSS) Integrated Sampling Plan (referred to herein as the Plan). It provides the Plan’s purpose and objectives, and briefly describes the Underground Test Area (UGTA) Activity, including the conceptual model and regulatory requirements as they pertain to groundwater sampling. Background information on other NNSS groundwater monitoring programs—the Routine Radiological Environmental Monitoring Plan (RREMP) and Community Environmental Monitoring Program (CEMP)—and their integration with the Plan are presented. Descriptions of the evaluations, comments, and responses of two Sampling Plan topical committees are also included.

  18. The decision to access patient information from a social media site: what would you do?

    Science.gov (United States)

    Jent, Jason F; Eaton, Cyd K; Merrick, Melissa T; Englebert, Nicole E; Dandes, Susan K; Chapman, Ana V; Hershorin, Eugene R

    2011-10-01

    The current study examined the prevalence with which healthcare providers use a social media site (SMS) account (e.g., Facebook), the extent to which they use SMSs in clinical practice, and their decision-making process after accessing patient information from an SMS. Pediatric faculty and trainees from a medical school campus were provided a SMS history form and seven fictional SMS adolescent profile vignettes that depicted concerning information. Participants were instructed to rate their personal use and beliefs about SMSs and to report how they would respond if they obtained concerning information about an adolescent patient from their public SMS profile. Healthcare providers generally believed it not to be an invasion of privacy to conduct an Internet/SMS search of someone they know. A small percentage of trainees reported a personal history of conducting an Internet search (18%) or an SMS search (14%) for a patient. However, no faculty endorsed a history of conducting searches for patients. Faculty and trainees also differed in how they would respond to concerning SMS adolescent profile information. The findings that trainees are conducting Internet/SMS searches of patients and that faculty and trainees differ in how they would respond to concerning profile information suggest the need for specific guidelines regarding the role of SMSs in clinical practice. Practice, policy, and training implications are discussed. Copyright © 2011 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  19. New Mexico state information handbook formerly utilized sites remedial action program

    International Nuclear Information System (INIS)

    1980-01-01

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Informaion Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New Mexico. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations

  20. Different methods of informing the public on projected sites of nuclear generating stations. Results in France

    International Nuclear Information System (INIS)

    Taccoen, L.B.C.

    1977-01-01

    The situation in France of local public opinion concerning nuclear power stations is very different, according to the region in question. It seems that in industrialized regions, where the inhabitants are already familiar with nuclear energy, public opinion is much more open to the installation of new reactors. In regions which are only slightly industrialized, however, the prejudices of the population against nuclear energy can be very strong. This situation is quite serious because it could lead to an even greater widening of the development gap between various regions in France. Electricite de France has thus been led to develop a program of public information concerning the problems of nuclear energy. In practice, this program consists of: a policy of active presence in meeting and debates as well as at the actual site; eventual opening of information centers; and organization of visists of existing nuclear power stations [fr

  1. New Mexico state information handbook formerly utilized sites remedial action program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-31

    This volume is one of a series produced under contract with the DOE, by Politech Corporation to develop a legislative and regulatory data base to assist the FUSRAP management in addressing the institutional and socioeconomic issues involved in carrying out the Formerly Utilized Sites Remedial Action Program. This Informaion Handbook series contains information about all relevant government agencies at the Federal and state levels, the pertinent programs they administer, each affected state legislature, and current Federal and state legislative and regulatory initiatives. This volume is a compilation of information about the State of New Mexico. It contains: a description of the state executive branch structure; a summary of relevant state statutes and regulations; a description of the structure of the state legislature, identification of the officers and committee chairmen, and a summary of recent relevant legislative action; and the full text of relevant statutes and regulations.

  2. Review of a site developer's geo-scientific data and site-characterisation information to support repository certification

    International Nuclear Information System (INIS)

    Peake, R.T.; Byrum, C.; Ghose, S.

    2007-01-01

    The Waste Isolation Pilot Plant (WIPP) in New Mexico is a first-of-a-kind deep geologic facility for the disposal of transuranic (TRU) radioactive waste from weapons production in the United States. In 1993, Congress authorised the Environmental Protection Agency (EPA) to develop and implement WIPP-site-specific compliance criteria based on the general safety and environmental standards in EPA's high-level and transuranic radioactive waste regulations [1]. EPA published its site-specific regulations [2] in 1996 and certified WIPP to open in 1998. This regulatory framework set the stage for balancing diverse input data, provided a structure for document development, provided a mechanism for interaction between EPA and the Department of Energy (DOE), and provided a guide to support our review of WIPP's safety assessment. EPA's involvement continues during WIPP's operational phase. Confidence in repository site geo-scientific data enhances the regulator's ability to make a credible and defensible certification (licensing) decision and to communicate the basis for the decision to the public. Lack of confidence in the data can lead to lack of credibility about site suitability. Clear regulations and specific quality standards can enhance the quality of site-characterisation documentation and assist the regulator in its approval process of the site. In EPA's regulations, documentation is required on numerous issues, and EPA supplemented this with guidance. High-quality documentation is essential, especially for EPA. In the certification process for WIPP, the documentation in the record and our written interpretation of the record was what was used in legal proceedings that followed EPA's certification of WIPP. EPA and DOE had frequent and generally open communication. During formal regulatory proceedings, all communication had to be documented. Some decisions were made at the staff level, but major decisions were typically addressed and resolved through correspondence

  3. Information Security Controls against Cross-Site Request Forgery Attacks on Software Applications of Automated Systems

    Science.gov (United States)

    Barabanov, A. V.; Markov, A. S.; Tsirlov, V. L.

    2018-05-01

    This paper presents statistical results and their consolidation, which were received in the study into security of various web-application against cross-site request forgery attacks. Some of the results were received in the study carried out within the framework of certification for compliance with information security requirements. The paper provides the results of consolidating information about the attack and protection measures, which are currently used by the developers of web-applications. It specifies results of the study, which demonstrate various distribution types: distribution of identified vulnerabilities as per the developer type (Russian and foreign), distribution of the security measures used in web-applications, distribution of the identified vulnerabilities as per the programming languages, data on the number of security measures that are used in the studied web-applications. The results of the study show that in most cases the developers of web-applications do not pay due attention to protection against cross-site request forgery attacks. The authors give recommendations to the developers that are planning to undergo a certification process for their software applications.

  4. Shifts of Gamma Phase across Primary Visual Cortical Sites Reflect Dynamic Stimulus-Modulated Information Transfer.

    Science.gov (United States)

    Besserve, Michel; Lowe, Scott C; Logothetis, Nikos K; Schölkopf, Bernhard; Panzeri, Stefano

    2015-01-01

    Distributed neural processing likely entails the capability of networks to reconfigure dynamically the directionality and strength of their functional connections. Yet, the neural mechanisms that may allow such dynamic routing of the information flow are not yet fully understood. We investigated the role of gamma band (50-80 Hz) oscillations in transient modulations of communication among neural populations by using measures of direction-specific causal information transfer. We found that the local phase of gamma-band rhythmic activity exerted a stimulus-modulated and spatially-asymmetric directed effect on the firing rate of spatially separated populations within the primary visual cortex. The relationships between gamma phases at different sites (phase shifts) could be described as a stimulus-modulated gamma-band wave propagating along the spatial directions with the largest information transfer. We observed transient stimulus-related changes in the spatial configuration of phases (compatible with changes in direction of gamma wave propagation) accompanied by a relative increase of the amount of information flowing along the instantaneous direction of the gamma wave. These effects were specific to the gamma-band and suggest that the time-varying relationships between gamma phases at different locations mark, and possibly causally mediate, the dynamic reconfiguration of functional connections.

  5. Premature ovarian insufficiency: Pathogenesis and management

    Directory of Open Access Journals (Sweden)

    Anna J Fenton

    2015-01-01

    Full Text Available The term premature ovarian insufficiency (POI describes a continuum of declining ovarian function in a young woman, resulting in an earlier than average menopause. It is a term that reflects the variable nature of the condition and is substantially less emotive than the formerly used "premature ovarian failure" which signaled a single event in time. Contrary to the decline in the age of menarche seen over the last 3-4 decades there has been no similar change in the age of menopause. In developed nations, the average age for cessation of menstrual cycles is 50-52 years. The age is younger among women from developing nations. Much has been written about POI despite a lack of good data on the incidence of this condition. It is believed that 1% of women under the age of 40 years and 0.1% under the age of 30 years will develop POI. Research is increasingly providing information about the pathogenesis and treatments are being developed to better preserve ovarian function during cancer treatment and to improve fertility options. This narrative review summarizes the current literature to provide an approach to best practice management of POI.

  6. Is hospital information system relevant to detect surgical site infection? Findings from a prospective surveillance study in posterior instrumented spinal surgery.

    Science.gov (United States)

    Boetto, J; Chan-Seng, E; Lonjon, G; Pech, J; Lotthé, A; Lonjon, N

    2015-11-01

    Spinal instrumentation has a high rate of surgical site infection (SSI), but results greatly vary depending on surveillance methodology, surgical procedures, or quality of follow-up. Our aim was to study true incidence of SSI in spinal surgery by significant data collection, and to compare it with the results obtained through the hospital information system. This work is a single center prospective cohort study that included all patients consecutively operated on for spinal instrumentation by posterior approach over a six-month period regardless the etiology. For all patients, a "high definition" prospective method of surveillance was performed by the infection control (IC) department during at least 12 months after surgery. Results were then compared with findings from automatic surveillance though the hospital information system (HIS). One hundred and fifty-four patients were included. We found no hardly difference between "high definition" and automatic surveillance through the HIS, even if HIS tended to under-estimate the infection rate: rate of surgical site infection was 2.60% and gross SSI incidence rate via the hospital information system was 1.95%. Smoking and alcohol consumption were significantly related to a SSI. Our SSI rates to reflect the true incidence of infectious complications in posterior instrumented adult spinal surgery in our hospital and these results were consistent with the lower levels of published infection rate. In-house surveillance by surgeons only is insufficiently sensitive. Further studies with more patients and a longer inclusion time are needed to conclude if SSI case detection through the HIS could be a relevant and effective alternative method. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  7. Pollution distribution of heavy metals in surface soil at an informal electronic-waste recycling site.

    Science.gov (United States)

    Fujimori, Takashi; Takigami, Hidetaka

    2014-02-01

    We studied distribution of heavy metals [lead (Pb), copper (Cu) and zinc (Zn)] in surface soil at an electronic-waste (e-waste) recycling workshop near Metro Manila in the Philippines to evaluate the pollution size (spot size, small area or the entire workshop), as well as to assess heavy metal transport into the surrounding soil environment. On-site length-of-stride-scale (~70 cm) measurements were performed at each surface soil point using field-portable X-ray fluorescence (FP-XRF). The surface soil at the e-waste recycling workshop was polluted with Cu, Zn and Pb, which were distributed discretely in surface soil. The site was divided into five areas based on the distance from an entrance gate (y-axis) of the e-waste recycling workshop. The three heavy metals showed similar concentration gradients in the y-axis direction. Zn, Pb and Cu concentrations were estimated to decrease to half of their maximum concentrations at ~3, 7 and 7 m from the pollution spot, respectively, inside the informal e-waste recycling workshop. Distance from an entrance may play an important role in heavy metal transport at the soil surface. Using on-site FP-XRF, we evaluated the metal ratio to characterise pollution features of the solid surface. Variability analysis of heavy metals revealed vanishing surficial autocorrelation over metre ranges. Also, the possibility of concentration prediction at unmeasured points using geostatistical kriging was evaluated, and heavy metals had a relative "small" pollution scales and remained inside the original workshop compared with toxic organohalogen compounds. Thus, exposure to heavy metals may directly influence the health of e-waste workers at the original site rather than the surrounding habitat and environmental media.

  8. Digital divide 2.0: the role of social networking sites in seeking health information online from a longitudinal perspective.

    Science.gov (United States)

    Feng, Yang; Xie, Wenjing

    2015-01-01

    Adopting a longitudinal angle, this study analyzed data from the Pew Internet's Health Tracking Survey in 2006, 2008, and 2010 to identify potential communication inequalities in social networking site use. Results showed that with the growing role of social networking site use in predicting people's likelihood of seeking health information online, the socioeconomic and demographic factors that contributed to the disparities in social networking site use could also lead to disparities in seeking health information online. Also, results indicated that people are more likely to seek heath-related information online if they or their close family or friends have a chronic disease situation.

  9. The IAEA's WorldAtom Internet site: International news and information services

    International Nuclear Information System (INIS)

    Kyd, D.R.

    2000-01-01

    The International Atomic Energy Agency (IAEA) provides news and public information services via the Internet through its WorldAtom home page. The page is accessible at www.iaea.org/worldatom. Following are brief highlights of the items available on the site by clicking Press Centre, Reference Centre, or other links: Daily Press Review: Summaries of selected news items pertaining to global nuclear developments and the IAEA's work are provided each day, drawing upon a wide range of global media sources. IAEA NewsBriefs: Regularly featured are updates about IAEA activities related to areas of safety, technology transfer, and nuclear safeguards. Meetings and training courses: News about IAEA-sponsored symposia, seminars, and other meetings, as well as information about international meetings on atomic energy sponsored by other organizations, are updated on a daily basis. Press releases and statements: All IAEA press releases and media advisories since 1995 are accessible on the site. Topical and feature pages: In-depth coverage and links to information resources within and outside the IAEA are regularly given to selected topics of high international interest involving the IAEA. IAEA publications: listings and overviews of IAEA technical reports, safety standards, and other publications are updated as they are issued. Scientific and technical information: WorldAtom includes links (Reference Centre) to the International Nuclear Information System, IAEA's extensive bibliographic database of references and resources, to the nuclear database, and to departmental pages at IAEA that focus on IAEA programs and activities. IAEA documents: Electronic versions of official IAEA documents are added as they are issued. These documents include the texts and status lists of international conventions under IAEA auspices; IAEA information circulars to member states; IAEA annual reports (since 1995); and background reports and documents for the IAEA General Conference related to

  10. Decree of May 4, 2015 creating a Commission of Information on ancient Pacific sites of nuclear experimentations

    International Nuclear Information System (INIS)

    Le Drian, Jean-Yves

    2015-01-01

    This official publication indicates the mission and composition of the Commission of Information which has been created to gather information and inform the public on the impact on health and on the environment of nuclear tests performed in the Mururoa and Fangatofa sites. It also describes how this Commission will operate

  11. Providing Meteorological Information for Controlled Burns at the Savannah River Site

    International Nuclear Information System (INIS)

    Buckley, R.

    1999-01-01

    Regional and local weather information are important for a variety of applications at the Savannah River Site (SRS), a Department of Energy (DOE) facility covering approximately 800 square kilometers of southwest South Carolina east of the Savannah River. For example, meteorological observations and forecasts are used to assess the consequences of an accidental radiological or chemical release. Traditionally, hazards posed by SRS operations have been associated with nuclear reactors, chemical reprocessing plants, fuel fabrication, or waste-vitrification facilities. However, recent events have shown site-specific meteorology to be a valuable tool to the United States Forest Service (USFS) in mitigating potential hazards from controlled burns that are conducted at the SRS. Prescribed burns at the SRS are important for a variety of reasons. The removal of thick undergrowth allows wildlife to more easily feed and migrate, accelerates the growth of young pine stands, and controls certain diseases that affect local pine forests (e.g. Adams et al. 1973). In addition, the removal of twigs, pine needles, or leaves (a fuel source) reduces the chance of serious wildfire damage. However, the threat of smoke inhalation and reduced visibility requires careful planning on the part of the fire professionals. At the SRS, approximately 100 square kilometers of land per year are burned in a controlled manner, mainly in the spring.To reduce the potentially harmful effects to any onsite activity, it is important that USFS personnel understand current and predicted weather patterns within the area. This paper discusses two sources of meteorological information that are provided to SRS-USFS personnel for use in planning forest burns: (1) a meteorological tower system which provides current data from a series of onsite locations, and (2) an operational prognostic mesoscale model used to generate forecast information. The forecast data supplements the basic National Weather Service (NWS

  12. Pancreatic insufficiency secondary to abdominal radiotherapy

    International Nuclear Information System (INIS)

    Dookeran, K.A.; Thompson, M.M.; Allum, W.H.

    1993-01-01

    Delayed post-irradiation steatorrhoea secondary to acute pancreatic insufficiency is rare. The authors describe a case occurring in a patient 23 years following radical abdominal radiotherapy for testicular seminoma. (Author)

  13. Pancreatic insufficiency secondary to abdominal radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Dookeran, K.A.; Thompson, M.M.; Allum, W.H. (Leicester Royal Infirmary (United Kingdom). Dept. of Surgery)

    1993-02-01

    Delayed post-irradiation steatorrhoea secondary to acute pancreatic insufficiency is rare. The authors describe a case occurring in a patient 23 years following radical abdominal radiotherapy for testicular seminoma. (Author).

  14. Are video sharing web sites a useful source of information on hypertension?

    Science.gov (United States)

    Kumar, Nilay; Pandey, Ambarish; Venkatraman, Anand; Garg, Neetika

    2014-07-01

    Hypertension (HTN) is a prevalent and growing public health problem in the United States and worldwide. Video sharing Web sites such as YouTube could potentially influence patient behaviors via properties of interpersonal and mass media communication. We conducted this cross-sectional study to assess the accuracy and content of YouTube videos on HTN and understand how viewers interact with this online information. We analyzed 209 videos (31.57 hours) of which 63% were classified as useful, 33% as misleading, and 4% represented patient's personal experiences. Number of views per day and "likes" were significantly lower for useful videos. Approximately half the misleading videos contained product advertisements, 70% advocated unproven alternative treatments, and 91% targeted patients. Viewer engagement (number of views) was a poor predictor of usefulness and/or content whereas source of upload, and target audiences were good predictors of usefulness and/or content. Videos uploaded by university channels and/or professional organizations that targeted physicians had a 99.4% (P < .001) probability of being useful whereas videos uploaded by individuals with unknown credentials that targeted patients had a 21.2% (P < .001) probability of being useful. A majority of HTN-related videos on YouTube are useful. Viewer engagement is significantly higher with videos that contain misleading and/or erroneous information in comparison to videos that contain useful information. Copyright © 2014 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.

  15. Geochemical information for sites contaminated with low-level radioactive wastes: II. St. Louis Airport Storage Site

    International Nuclear Information System (INIS)

    Seeley, F.G.; Kelmers, A.D.

    1985-01-01

    The St. Louis Airport Storage Site (SLASS) became radioactively contaminated as a result of wastes that were being stored from operations to recover uranium from pitchblende ores in the 1940s and 1950s. The US Department of Energy is considering various remedial action options for the SLASS under the Formerly Utilized Site Remedial Action Program (FUSRAP). This report describes the results of geochemical investigations, carried out to support the FUSRAP activities and to aid in quantifying various remedial action options. Soil and groundwater samples from the site were characterized, and sorption ratios for uranium and radium and apparent concentration limit values for uranium were measured in soil/groundwater systems by batch contact methodology. The uranium and radium concentrations in soil samples were significantly above background near the old contaminated surface horizon (now at the 0.3 - to 0.9 - m depth); the maximum values were 1566 μg/g and 101 pCi/g, respectively. Below about the 6 - m depth, the concentrations appeared to be typical of those naturally present in soils of this area (3.8 +- 1.2 μg/g and 3.1 +- 0.6 pCi/g). Uranium sorption ratios showed stratigraphic trends but were generally moderate to high (100 to 1000 L/kg). The sorption isotherm suggested an apparent uranium concentration limit of about 200 mg/L. This relatively high solubility can probably be correlated with the carbonate content of the soil/groundwater systems. The lower sorption ratio values obtained from the sorption isotherm may have resulted from changes in the experimental procedure or the groundwater used. The SLASS appears to exhibit generally favorable behavior for the retardation of uranium solubilized from waste in the site. Parametric tests were conducted to estimate the sensitivity of uranium sorption and solubility to the pH and carbonate content of the system

  16. 10 CFR Appendix IV to Part 960 - Types of Information for the Nomination of Sites as Suitable for Characterization

    Science.gov (United States)

    2010-01-01

    ... contained in other areas of similar size in the geologic setting. • Past and present drilling and mining.... The types of information to support this description should include— • Topography of the site...

  17. Overall Analysis of Meteorological Information in the KAERI Site (2006 Annual Report)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, E. H.; Choi, G. S.; Choi, S. D

    2007-07-15

    Inspection and repair of tower structure and lift, instrument calibration have been done in the scope of 'Environmental Radiation Monitoring Around the Nuclear Facilities' project. Wind direction, wind speed, temperature, humidity at 67m, 27m, and 10m height and temperature, humidity, atmospheric pressure, solar radiation, precipitation, and visibility at surface have been measured and analyzed with statistical methods. At the site, the prevailing wind directions were N in winter, SW in 2nd, E in 3rd quaters. The calm distributed 14.7% at 67m, 33.2% at 27m, 57.3% at 10m height. Wireless data transmission to MIPS(Meteorological Information Processing System) has been done after collection in the DAS where environmental assessment can be done by the developed simulation programs in both cases of normal operation and emergency.

  18. Use of online social networking sites among pre-service information technology teachers

    Directory of Open Access Journals (Sweden)

    Elif Buğra Kuzu

    2013-12-01

    Full Text Available The current study aimed to investigate the current status and perceptions of pre-service information technology (IT teachers regarding the use of online social networking sites (SNSs. The investigation was further supported through participant feedback regarding the design and implementation of a blended learning environment to embrace online SNSs in instructional settings. The study had a qualitative nature and employed a focus group interview to collect data. Participants were ten fourth graders who were randomly selected from voluntary undergraduate students enrolled at an IT education department of a Turkish state university. Researchers resorted to content analysis through an inductive coding process, provided themes addressing student perceptions and needs, and proposed implications and suggestions for further instructional practices.

  19. Information report on nuclear safety and radiation protection of the Romans site - Issue 2014

    International Nuclear Information System (INIS)

    2015-06-01

    In compliance with the French Code of the Environment, this annual document describes the arrangements regarding nuclear safety and radiation protection, reports incidents and accidents of nuclear safety and radiation protection which must be declared according to this Code and which occurred within the installation, as well as the actions undertaken to limit their development and the consequences for people health for the environment, describes the nature and results of measurements of radioactive and not radioactive releases by the installation in the environment, describes the nature and quantities of radioactive wastes which are warehoused on the installation site as well as measures to limit their volume and their impact on health and on the environment, notably in soils and waters. After a presentation of the AREVA plant located in Romans-sur-Isere which comprises two basic nuclear installations (INB) and where fuel assemblies are manufactured, the different parts of this report address the measures regarding nuclear safety and radiation protection, nuclear events according to the INES scale, the management of releases by the different installations of this site and the control of the environment, the management of radioactive wastes, and the actions undertaken regarding information and transparency. Recommendations of the CHSCT are also reported

  20. Information report on nuclear safety and radiation protection of the Romans site - Issue 2012

    International Nuclear Information System (INIS)

    2013-06-01

    In compliance with the French Code of the Environment, this annual document describes the arrangements regarding nuclear safety and radiation protection, reports incidents and accidents of nuclear safety and radiation protection which must be declared according to this Code and which occurred within the installation, as well as the actions undertaken to limit their development and the consequences for people health for the environment, describes the nature and results of measurements of radioactive and not radioactive releases by the installation in the environment, describes the nature and quantities of radioactive wastes which are warehoused on the installation site as well as measures to limit their volume and their impact on health and on the environment, notably in soils and waters. After a presentation of the AREVA plant located in Romans-sur-Isere which comprises two basic nuclear installations (INB) and where fuel assemblies are manufactured, the different parts of this report address the measures regarding nuclear safety and radiation protection, nuclear events according to the INES scale, the management of releases by the different installations of this site and the control of the environment, the management of radioactive wastes, and the actions undertaken regarding information and transparency. Recommendations of the CHSCT are also reported

  1. Information report on nuclear safety and radiation protection of the Romans site - Issue 2013

    International Nuclear Information System (INIS)

    2014-06-01

    In compliance with the French Code of the Environment, this annual document describes the arrangements regarding nuclear safety and radiation protection, reports incidents and accidents of nuclear safety and radiation protection which must be declared according to this Code and which occurred within the installation, as well as the actions undertaken to limit their development and the consequences for people health for the environment, describes the nature and results of measurements of radioactive and not radioactive releases by the installation in the environment, describes the nature and quantities of radioactive wastes which are warehoused on the installation site as well as measures to limit their volume and their impact on health and on the environment, notably in soils and waters. After a presentation of the AREVA plant located in Romans-sur-Isere which comprises two basic nuclear installations (INB) and where fuel assemblies are manufactured, the different parts of this report address the measures regarding nuclear safety and radiation protection, nuclear events according to the INES scale, the management of releases by the different installations of this site and the control of the environment, the management of radioactive wastes, and the actions undertaken regarding information and transparency. Recommendations of the CHSCT are also reported

  2. Online information about risks and benefits of screening mammography in 10 European countries: An observational Web sites analysis.

    Science.gov (United States)

    Spagnoli, Laura; Navaro, Monica; Ferrara, Pietro; Del Prete, Viola; Attena, Francesco

    2018-06-01

    Most publications about breast cancer do not provide accurate and comprehensive information, giving few or no data about risk/benefit ratios. We conducted a comparative study among 10 European countries about health information on breast cancer screening, assessing the first 10 Web sites addressing the general public that appeared following an Internet search.With the help of medical residents involved in the EuroNet MRPH Association, we analyzed the first 30 results of an Internet search in 10 European countries to determine the first 10 sites that offered screening mammography. We searched for the following information: source of information, general information on mammography and breast cancer screening, potential harms and risks (false positives, false positives after biopsy, false negatives, interval cancer, overdiagnosis, lead-time bias, and radiation exposure), and potential benefits (reduced mortality and increased survival).The United Kingdom provided the most information: 39 of all 70 possible identified risks (56%) were reported on its sites. Five nations presented over 35% of the possible information (United Kingdom, Spain, France, Ireland, and Italy); the others were under 30% (Portugal, Poland, Slovenia, Netherlands, and Croatia). Regarding the benefits, sites offering the most complete information were those in France (95%) and Poland (90%).Our results suggest that, despite consensus in the scientific community about providing better information to citizens, further efforts are needed to improve information about breast cancer screening. That conclusion also applies to countries showing better results. We believe that there should be greater coordination in this regard throughout Europe.

  3. Repository site data and information in bedded salt: Palo Duro Basin, Texas

    International Nuclear Information System (INIS)

    Tien, P.; Nimick, F.B.; Muller, A.B.; Davis, P.A.; Guzowski, R.V.; Duda, L.E.; Hunter, R.L.

    1983-11-01

    This report is a compilation of data from the literature on the Palo Duro Basin. The Palo Duro Basin is a structural basin, about 150 miles long and 80 miles wide, that is a part of the much larger Permian Basin. The US Department of Energy is investigating the Palo Duro Basin as a potentially suitable area for the site of a repository for the disposal of high-level radioactive waste. Sediments overlying the Precambrian basement range from about 5000 to about 11,000 ft in thickness and from Cambrian to Holocene in age. The strata in the Palo Duro Basin that are of primary interest to the Department of Energy are the bedded salts of the Permian San Andres Formation. The total thickness of the bedded salts is about 2000 ft. The geology of the Palo Duro Basin is well understood. A great deal of information exists on the properties of salt, although much of the available information was not collected in the Palo Duro Basin. Mineral resources are not currently being exploited from the center of the Palo Duro Basin at depth, although the possibility of exploration for and development of such resources can not be ruled out. The continued existence of salts of Permian age indicates a lack of any large amount of circulating ground water. The hydrology of the pre-Tertiary rocks, however, is currently too poorly understood to carry out detailed, site-specific hydrologic modeling with a high degree of confidence. In general, ground water flows from west to east in the Basin. There is little or no hydraulic connection between aquifers above and below the salt sequences. Potable water is pumped from the Ogallala aquifer. Most of the other aquifers yield only nonpotable water. More extensive hydrological data are needed for detailed future modeling in support of risk assessment for a possible repository for high-level waste in the Palo Duro Basin. 464 references

  4. What Factors Impact Consumer Perception of the Effectiveness of Health Information Sites? An Investigation of the Korean National Health Information Portal.

    Science.gov (United States)

    Choung, Ji Tae; Lee, Yoon Seong; Jo, Heui Sug; Shim, Minsun; Lee, Hun Jae; Jung, Su Mi

    2017-07-01

    Lay public's concerns around health and health information are increasing. In response, governments and government agencies are establishing websites to address such concerns and improve health literacy by providing better access to validated health information. Since 2011, the Korean government has constructed the National Health Information Portal (NHIP) website run in collaboration with the Korean Academy of Medical Sciences (KAMS). This study therefore aimed to 1) examine consumer use of NHIP, with respect to the usage patterns, evaluation on health information provided, and perceived effectiveness of the site; and 2) identify factors that may impact perceived effectiveness of the site. An online survey was conducted with 164 NHIP users, recruited through a popup window on the main screen of the portal website from October to November 2015. The significant predicting factors supported by the data include the relevance of health information on the site, the usefulness of information in making health decisions, and the effective visualization of information. These factors can inform future efforts to design more effective health information websites, possibly based on metadata systems, to further advance the lay public's information seeking and health literacy. © 2017 The Korean Academy of Medical Sciences.

  5. Information asymmetry, social networking site word of mouth, and mobility effects on social commerce in Korea.

    Science.gov (United States)

    Hwang, In Jeong; Lee, Bong Gyou; Kim, Ki Youn

    2014-02-01

    The purpose of this research is to examine the issues that affect customers' behavioral character and purchasing behavior. The study proposes a research hypothesis with independent variables that include social presence, trust, and information asymmetry, and the dependent variable purchase decision making, to explain differentiated customer decision making processes in social commerce (S-commerce). To prove the hypothesis, positive verification was performed by focusing on mediating effects through a customer uncertainty variable and moderating effects through mobility and social networking site word of mouth (SNS WOM) variables. The number of studies on customer trends has rapidly increased together with the market size of S-commerce. However, few studies have examined the negative variables that make customers hesitant to make decisions in S-commerce. This study investigates the causes of customer uncertainty and focuses on deducing the control variables that offset this negative relationship. The study finds that in customers' S-commerce purchasing actions, the SNS WOM and mobility variables show control effects between information asymmetry and uncertainty and between trust and uncertainty. Additionally, this research defines the variables related to customer uncertainty that are hidden in S-commerce, and statistically verifies their relationship. The research results can be used in Internet marketing practices to establish marketing mix strategies for customer demand or as research data to predict customer behavior. The results are scientifically meaningful as a precedent for research on customers in S-commerce.

  6. Protected health information on social networking sites: ethical and legal considerations.

    Science.gov (United States)

    Thompson, Lindsay A; Black, Erik; Duff, W Patrick; Paradise Black, Nicole; Saliba, Heidi; Dawson, Kara

    2011-01-19

    Social networking site use is increasingly common among emerging medical professionals, with medical schools even reporting disciplinary student expulsion. Medical professionals who use social networking sites have unique responsibilities since their postings could violate patient privacy. However, it is unknown whether students and residents portray protected health information and under what circumstances or contexts. The objective of our study was to document and describe online portrayals of potential patient privacy violations in the Facebook profiles of medical students and residents. A multidisciplinary team performed two cross-sectional analyses at the University of Florida in 2007 and 2009 of all medical students and residents to see who had Facebook profiles. For each identified profile, we manually scanned the entire profile for any textual or photographic representations of protected health information, such as portrayals of people, names, dates, or descriptions of procedures. Almost half of all eligible students and residents had Facebook profiles (49.8%, or n=1023 out of 2053). There were 12 instances of potential patient violations, in which students and residents posted photographs of care they provided to individuals. No resident or student posted any identifiable patient information or likeness in text form. Each instance occurred in developing countries on apparent medical mission trips. These portrayals increased over time (1 in the 2007 cohort; 11 in 2009; P = .03). Medical students were more likely to have these potential violations on their profiles than residents (11 vs 1, P = .04), and there was no difference by gender. Photographs included trainees interacting with identifiable patients, all children, or performing medical examinations or procedures such as vaccinations of children. While students and residents in this study are posting photographs that are potentially violations of patient privacy, they only seem to make this lapse in the

  7. Protected Health Information on Social Networking Sites: Ethical and Legal Considerations

    Science.gov (United States)

    2011-01-01

    Background Social networking site use is increasingly common among emerging medical professionals, with medical schools even reporting disciplinary student expulsion. Medical professionals who use social networking sites have unique responsibilities since their postings could violate patient privacy. However, it is unknown whether students and residents portray protected health information and under what circumstances or contexts. Objective The objective of our study was to document and describe online portrayals of potential patient privacy violations in the Facebook profiles of medical students and residents. Methods A multidisciplinary team performed two cross-sectional analyses at the University of Florida in 2007 and 2009 of all medical students and residents to see who had Facebook profiles. For each identified profile, we manually scanned the entire profile for any textual or photographic representations of protected health information, such as portrayals of people, names, dates, or descriptions of procedures. Results Almost half of all eligible students and residents had Facebook profiles (49.8%, or n=1023 out of 2053). There were 12 instances of potential patient violations, in which students and residents posted photographs of care they provided to individuals. No resident or student posted any identifiable patient information or likeness in text form. Each instance occurred in developing countries on apparent medical mission trips. These portrayals increased over time (1 in the 2007 cohort; 11 in 2009; P = .03). Medical students were more likely to have these potential violations on their profiles than residents (11 vs 1, P = .04), and there was no difference by gender. Photographs included trainees interacting with identifiable patients, all children, or performing medical examinations or procedures such as vaccinations of children. Conclusions While students and residents in this study are posting photographs that are potentially violations of patient

  8. Information Needs and Information Competencies: A Case Study of the Off-Site Supervision of Financial Institutions in Brazil

    Science.gov (United States)

    Miranda, Silvania V.; Tarapanoff, Kira M. A.

    2008-01-01

    Introduction: The paper deals with the identification of the information needs and information competencies of a professional group. Theoretical basis: A theoretical relationship between information needs and information competencies as subjects is proposed. Three dimensions are examine: cognitive, affective and situational. The recognition of an…

  9. Pancreatic Exocrine Insufficiency in Pancreatic Cancer.

    Science.gov (United States)

    Vujasinovic, Miroslav; Valente, Roberto; Del Chiaro, Marco; Permert, Johan; Löhr, J-Matthias

    2017-02-23

    Abstract : Cancer patients experience weight loss for a variety of reasons, commencing with the tumor's metabolism (Warburg effect) and proceeding via cachexia to loss of appetite. In pancreatic cancer, several other factors are involved, including a loss of appetite with a particular aversion to meat and the incapacity of the pancreatic gland to function normally when a tumor is present in the pancreatic head. Pancreatic exocrine insufficiency is characterized by a deficiency of the enzymes secreted from the pancreas due to the obstructive tumor, resulting in maldigestion. This, in turn, contributes to malnutrition, specifically a lack of fat-soluble vitamins, antioxidants, and other micronutrients. Patients with pancreatic cancer and pancreatic exocrine insufficiency have, overall, an extremely poor prognosis with regard to surgical outcome and overall survival. Therefore, it is crucial to be aware of the mechanisms involved in the disease, to be able to diagnose pancreatic exocrine insufficiency early on, and to treat malnutrition appropriately, for example, with pancreatic enzymes.

  10. 76 FR 32227 - DST Systems, Inc., Including On-Site Leased Workers From Comsys Information Technology Services...

    Science.gov (United States)

    2011-06-03

    ..., Inc., Including On-Site Leased Workers From Comsys Information Technology Services, Megaforce, and Kelly Services Kansas City, MO; DST Technologies, a Wholly Owned Subsidiary of DST Systems, Inc., Boston... Information Technology Services, Megaforce, and Kelly Services, Kansas City, Missouri (subject firm). The...

  11. Natura2000 : information and communication on the designation and management of Natura2000 sites : main report 3: towards integrated management

    NARCIS (Netherlands)

    Kruk, R.W.; Blust, de G.; Apeldoorn, van R.C.; Bouwma, I.M.; Sier, A.R.J.

    2010-01-01

    Natura2000 : information and communication on the designation and management of Natura2000 sites. For all member states information will be collected describing the necessary management approaches, their legal framework, public consultation procedures as well as timing, structure and content of

  12. Chemical Safety Information, Site Security and Fuels Regulatory Relief Act: Public Distribution of Off-Site Consequence Analysis Information Fact Sheet

    Science.gov (United States)

    Based on assessments of increased risk of terrorist/criminal activity, EPA and DOJ have issued a rule that allows public access to OCA information in ways that are designed to minimize likelihood of chemical accidents and public harm.

  13. A Novel Computational Method for Detecting DNA Methylation Sites with DNA Sequence Information and Physicochemical Properties.

    Science.gov (United States)

    Pan, Gaofeng; Jiang, Limin; Tang, Jijun; Guo, Fei

    2018-02-08

    DNA methylation is an important biochemical process, and it has a close connection with many types of cancer. Research about DNA methylation can help us to understand the regulation mechanism and epigenetic reprogramming. Therefore, it becomes very important to recognize the methylation sites in the DNA sequence. In the past several decades, many computational methods-especially machine learning methods-have been developed since the high-throughout sequencing technology became widely used in research and industry. In order to accurately identify whether or not a nucleotide residue is methylated under the specific DNA sequence context, we propose a novel method that overcomes the shortcomings of previous methods for predicting methylation sites. We use k -gram, multivariate mutual information, discrete wavelet transform, and pseudo amino acid composition to extract features, and train a sparse Bayesian learning model to do DNA methylation prediction. Five criteria-area under the receiver operating characteristic curve (AUC), Matthew's correlation coefficient (MCC), accuracy (ACC), sensitivity (SN), and specificity-are used to evaluate the prediction results of our method. On the benchmark dataset, we could reach 0.8632 on AUC, 0.8017 on ACC, 0.5558 on MCC, and 0.7268 on SN. Additionally, the best results on two scBS-seq profiled mouse embryonic stem cells datasets were 0.8896 and 0.9511 by AUC, respectively. When compared with other outstanding methods, our method surpassed them on the accuracy of prediction. The improvement of AUC by our method compared to other methods was at least 0.0399 . For the convenience of other researchers, our code has been uploaded to a file hosting service, and can be downloaded from: https://figshare.com/s/0697b692d802861282d3.

  14. A Novel Computational Method for Detecting DNA Methylation Sites with DNA Sequence Information and Physicochemical Properties

    Directory of Open Access Journals (Sweden)

    Gaofeng Pan

    2018-02-01

    Full Text Available DNA methylation is an important biochemical process, and it has a close connection with many types of cancer. Research about DNA methylation can help us to understand the regulation mechanism and epigenetic reprogramming. Therefore, it becomes very important to recognize the methylation sites in the DNA sequence. In the past several decades, many computational methods—especially machine learning methods—have been developed since the high-throughout sequencing technology became widely used in research and industry. In order to accurately identify whether or not a nucleotide residue is methylated under the specific DNA sequence context, we propose a novel method that overcomes the shortcomings of previous methods for predicting methylation sites. We use k-gram, multivariate mutual information, discrete wavelet transform, and pseudo amino acid composition to extract features, and train a sparse Bayesian learning model to do DNA methylation prediction. Five criteria—area under the receiver operating characteristic curve (AUC, Matthew’s correlation coefficient (MCC, accuracy (ACC, sensitivity (SN, and specificity—are used to evaluate the prediction results of our method. On the benchmark dataset, we could reach 0.8632 on AUC, 0.8017 on ACC, 0.5558 on MCC, and 0.7268 on SN. Additionally, the best results on two scBS-seq profiled mouse embryonic stem cells datasets were 0.8896 and 0.9511 by AUC, respectively. When compared with other outstanding methods, our method surpassed them on the accuracy of prediction. The improvement of AUC by our method compared to other methods was at least 0.0399 . For the convenience of other researchers, our code has been uploaded to a file hosting service, and can be downloaded from: https://figshare.com/s/0697b692d802861282d3.

  15. Antineoplastic treatment of patients with renal insufficiency

    International Nuclear Information System (INIS)

    Rajec, J.; Mego, M.; Rajec, J.

    2011-01-01

    Kidneys are the main route of elimination for many antineoplastic drugs and their metabolites. The kidney dysfunction may lead to the drug cumulation in organism with the resulting increased systemic toxicity. A lot of used cytostatics requires a dose modification at different levels of renal insufficiency. Due to the lack of data from clinical trials, the limiting of systemic toxicity is difficult especially in patients with severe renal impairment or patients undergoing chronic hemodialysis. The following article is focused on the preventive strategies dealing with recommended dosing modification of various antineoplastic agents in patients with renal insufficiency. (author)

  16. [Association between Williams syndrome and adrenal insufficiency].

    Science.gov (United States)

    Rchachi, Meryem; Larwanou, Maazou Mahamane; El Ouahabi, Hanan; Ajdi, Farida

    2017-01-01

    Williams syndrome is a developmental disorder including dysmorphia, cardiovascular malformations and a specific neuropsychological profile together with other associated disorders. We report the case of a 17-year old girl, born of a non-inbred marriage, with Williams syndrome discovered during an assessment of degree of failure to thrive. Its association with primary adrenal insufficiency makes it unique. Diagnosis is confirmed by cytogenetic and molecular analysis. Its management consists of the implementation of treatment for adrenal insufficiency associated with a clinico-biological monitoring.

  17. Information System Security: Air Force Web Site Administration, Policies, and Practices

    National Research Council Canada - National Science Library

    2002-01-01

    .... Subsequent reports will cover Web site administration within the Army and DoD. The Naval Audit Service plans to issue a separate report based on the audit of Web site administration within the Navy and the Marine Corps...

  18. Information report on nuclear safety and radiation protection of the Tricastin AREVA site - Issue 2013. Figures and information about nuclear safety and radiation protection of the Tricastin AREVA site - Issue 2013

    International Nuclear Information System (INIS)

    2014-06-01

    Published in compliance with the French code of the environment, this report first presents different aspects of the Areva's Tricastin site which comprises five basic nuclear installations or INBs, and seven ICPE (installation classified for the protection of the environment). The activities are dedicated to uranium conversion, uranium enrichment, uranium chemistry, industrial services, and fuel manufacturing. The report presents this important industrial site, describes the various measures regarding nuclear safety and radiation protection, reports nuclear events which occurred on this site and had to be declared, reports the management of releases by this site and the control of the environment. The next part addresses the management of the various wastes produced by the different installations present on this site. The management of other impacts is also reported. The last chapter reviews the actions undertaken in the field of transparency and information

  19. Information report on nuclear safety and radiation protection of the Tricastin AREVA site - Issue 2014. Figures and information about nuclear safety and radiation protection of the Tricastin AREVA site - Issue 2014

    International Nuclear Information System (INIS)

    2015-06-01

    Published in compliance with the French code of the environment, this report first presents different aspects of the Areva's Tricastin site which comprises five basic nuclear installations or INBs, and seven ICPE (installation classified for environment protection). The activities are dedicated to uranium conversion, uranium enrichment, uranium chemistry, industrial services, and fuel manufacturing. The report presents this important industrial site, describes the various measures regarding nuclear safety and radiation protection, reports nuclear events which occurred on this site and had to be declared, reports the management of releases by this site and the control of the environment. The next part addresses the management of the various wastes produced by the different installations present on this site. The management of other impacts is also reported. The last chapter reviews the actions undertaken in the field of transparency and information

  20. Using a Geographic Information System to Assess Site Suitability for Managed Aquifer Recharge using Stormwater Capture

    Science.gov (United States)

    Teo, E. K.; Harmon, R. E.; Beganskas, S.; Young, K. S.; Fisher, A. T.; Weir, W. B.; Lozano, S.

    2015-12-01

    We are completing a regional analysis of Santa Cruz and northern Monterey Counties, CA, to assess the conditions amenable to managed aquifer recharge using stormwater runoff. Communities and water supply agencies across CA are struggling to mitigate the ongoing drought and to develop secure and sustainable water supplies to support long-term municipal, agricultural, environmental and other needs. Enhanced storage of groundwater is an important part of this effort in many basins. This work is especially timely because of the recently enacted "Sustainable Groundwater Management Act" (SGMA), which requires the development of groundwater sustainability agencies and implementation of basin management plans in coming decades. Our analysis focuses specifically on the distributed collection of stormwater runoff, a water source that has typically been treated as a nuisance or waste, from drainages having an area on the order of 40-160 hectares. The first part of this project is a geographic information system (GIS) analysis using surface and subsurface data sets. Developing complete and accurate datasets across the study region required considerable effort to locate, assemble, co-register, patch, and reconcile information from many sources and scales. We have complete spatial coverage for surface data, but subsurface data is more limited in lateral extent. Sites that are most suitable for distributed stormwater capture supporting MAR have high soil infiltration capacity, are well-connected to an underlying aquifer with good transmissive and storage properties, and have space to receive MAR. Additional considerations include method of infiltration, slope, and land use and access. Based on initial consideration of surface data and slope, 7% of the complete study region appears to be "suitable or highly suitable" for MAR (in the top third of the rating system), but there is considerable spatial heterogeneity based on the distribution of shallow soils and bedrock geology.

  1. Information report on nuclear safety and radiation protection of the SOMANU site - Issue 2014

    International Nuclear Information System (INIS)

    2015-01-01

    Published in compliance with the French code of the environment, this report first presents different aspects of the SOMANU plant which is dedicated to the maintenance of materials and equipment from nuclear installations: location and environment, history, description of activities, regulatory framework. It describes the various measures regarding nuclear safety and radiation protection: general principles of nuclear safety, organization, presentation of the Areva's nuclear safety Charter, inspections and controls, measures regarding radiation protection. The next part addresses nuclear events which occurred on this site and had to be declared. The report gives an overview of activities and measures regarding the management of releases and the control of the environment. The next part addresses waste management: general considerations on radioactive waste management in France, description and classification of radioactive wastes present in the INB, management of conventional wastes. The management of other impacts is also reported. The last chapter reviews the actions undertaken in the field of transparency and information. Recommendations of the CHSCT are reported

  2. Information report on nuclear safety and radiation protection of the SOMANU site - Issue 2012

    International Nuclear Information System (INIS)

    2013-06-01

    Published in compliance with the French code of the environment, this report first presents different aspects of the SOMANU plant which is dedicated to the maintenance of materials and equipment from nuclear installations: location and environment, history, description of activities, regulatory framework. It describes the various measures regarding nuclear safety and radiation protection: general principles of nuclear safety, organization, presentation of the Areva's nuclear safety Charter, inspections and controls, measures regarding radiation protection. The next part addresses nuclear events which occurred on this site and had to be declared. The report gives an overview of activities and measures regarding the management of releases and the control of the environment. The next part addresses waste management: generalities on radioactive waste management in France, description and classification of radioactive wastes present in the INB, management of conventional wastes. The management of other impacts is also reported. The last chapter reviews the actions undertaken in the field of transparency and information. Recommendations of the CHSCT are reported

  3. AMH as Predictor of Premature Ovarian Insufficiency

    DEFF Research Database (Denmark)

    Lunding, Stine Aa; Aksglæde, Lise; Anderson, Richard A

    2015-01-01

    CONTEXT: The majority of Turner syndrome (TS) patients suffer from accelerated loss of primordial follicles. Low circulating levels of anti-Müllerian hormone (AMH) may predict the lack of spontaneous puberty in prepubertal girls and imminent premature ovarian insufficiency (POI) in TS women...

  4. Subchondral insufficiency fractures of the femoral head

    Energy Technology Data Exchange (ETDEWEB)

    Davies, M.; Cassar-Pullicino, V.N. [Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic and District Hospital, Oswestry, SY10 7AG, Shropshire (United Kingdom); Darby, A.J. [Department of Pathology, Robert Jones and Agnes Hunt Orthopaedic and District Hospital, Oswestry, SY10 7AG, Shropshire (United Kingdom)

    2004-02-01

    The aim of this study was to increase awareness of, and to show the variable clinical and radiological features of, subchondral insufficiency fractures of the femoral head. The clinical and radiological findings in 7 patients with subchondral insufficiency fractures of the femoral head were reviewed retrospectively. The diagnosis was confirmed histologically in 4 patients. Radiographs were performed in all patients, MRI in 5 and scintigraphy in 4 patients. Radiographs showed varying degrees of femoral head collapse in 4 patients. In the remaining 3 patients radiographs showed a normal femoral head, regional osteoporosis and focal sclerosis, respectively. Magnetic resonance imaging showed a low-signal band on T1- and T2-weighted images in the subchondral bone adjacent or parallel to the articular surface associated with bone marrow oedema. Scintigraphy showed increased uptake in the femoral head. Insufficiency fractures of the femoral head are easily overlooked or confused with avascular necrosis and, when there is significant joint destruction, osteoarthritis. Unsuspected insufficiency fracture of the femoral head can lead to significant and rapid loss of bone stock in osteoporotic patients waiting for arthroplasty for osteoarthritis. Increased awareness of this condition will hopefully lead to earlier diagnosis and a successful outcome of conservative treatment. (orig.)

  5. Information on biological health effects of ionizing radiation and radionuclides: the rule of a web site

    International Nuclear Information System (INIS)

    Comte, A.; Gaillard-Lecanu, E.; Flury-Herard, A.; Ourly, F.; Hemidy, P.; Lallemand, J.

    2006-01-01

    The purpose of this project is to provide a source of information on biological and health effects of radionuclides and ionizing radiation in an easy to use format. Reported work is made up of two distinct parts: data sheets for selected radionuclides and a web file. Data sheets: Specific radiation data sheets provide an overview of the properties, the environmental behaviour, the different pathways of human exposure and the biological and health consequences of selected radionuclides. Radionuclides that have been selected are those commonly dealt with in nuclear industry (and in other areas such as medicine) and released to the environment or naturally occurring (plutonium, tritium, carbon 14). Data sheets corresponding to the different radionuclides are based on the main sources of scientific information in dosimetry, epidemiology, radiobiology and radiation protection. These data sheets are intended for radiation protection specialists and physicians. They include: main physical and chemical characteristics, main radiation protection data: dose coefficients (public, workers), dose limits sources, total released estimate (nuclear industry, atmospheric tests, main pathway of human exposure and biological behaviour, biological and health effects, medical supervision, treatment a list of the main references, appendix providing accurate information. Web file: http://www-dsv.cea.fr/doc/carmin_ext/fond.php This web file provides a source of information on biological and health effects of ionizing radiation and biological basic knowledge of radiation protection. Available for consultation via Internet, compiled information provides, in a same file, subjects as varied as biological mechanisms, ionizing radiations action, biological and health effects, risk assessment This file is mainly intended to assist in informing and training of non-specialist readership (students, teaching on radiation protection basic knowledge. This electronic document is divided in three

  6. Information needs for characterization of high-level waste repository sites in six geologic media. Volume 1. Main report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1985-05-01

    Evaluation of the geologic isolation of radioactive materials from the biosphere requires an intimate knowledge of site geologic conditions, which is gained through precharacterization and site characterization studies. This report presents the results of an intensive literature review, analysis and compilation to delineate the information needs, applicable techniques and evaluation criteria for programs to adequately characterize a site in six geologic media. These media, in order of presentation, are: granite, shale, basalt, tuff, bedded salt and dome salt. Guidelines are presented to assess the efficacy (application, effectiveness, and resolution) of currently used exploratory and testing techniques for precharacterization or characterization of a site. These guidelines include the reliability, accuracy and resolution of techniques deemed acceptable, as well as cost estimates of various field and laboratory techniques used to obtain the necessary information. Guidelines presented do not assess the relative suitability of media. 351 refs., 10 figs., 31 tabs.

  7. Information needs for characterization of high-level waste repository sites in six geologic media. Volume 1. Main report

    International Nuclear Information System (INIS)

    1985-05-01

    Evaluation of the geologic isolation of radioactive materials from the biosphere requires an intimate knowledge of site geologic conditions, which is gained through precharacterization and site characterization studies. This report presents the results of an intensive literature review, analysis and compilation to delineate the information needs, applicable techniques and evaluation criteria for programs to adequately characterize a site in six geologic media. These media, in order of presentation, are: granite, shale, basalt, tuff, bedded salt and dome salt. Guidelines are presented to assess the efficacy (application, effectiveness, and resolution) of currently used exploratory and testing techniques for precharacterization or characterization of a site. These guidelines include the reliability, accuracy and resolution of techniques deemed acceptable, as well as cost estimates of various field and laboratory techniques used to obtain the necessary information. Guidelines presented do not assess the relative suitability of media. 351 refs., 10 figs., 31 tabs

  8. Adrenal insufficiency in pakistani hiv infected patients

    International Nuclear Information System (INIS)

    Afreen, B.; Khan, K.A.; Riaz, A.

    2017-01-01

    Background: Adrenal insufficiency (AI) is the most common endocrine complication among patients with AIDS/HIV infection and there are number of causes of AI in HIV patients. Human immunodeficiency virus directly as well as indirectly destroys adrenal glands. The estimates of its prevalence and severity vary. AI is the most life threatening but readily correctable endocrine complication that occurs in persons with HIV infection. This study was carried out to determine the frequency of Adrenal Insufficiency in HIV patients and their clinical features as proper diagnosis and timely treatment have been shown to improve quality of life and long-term mortality in AIDS patients. Methods: It was a cross sectional survey conducted at HIV clinic and Jinnah Allama Iqbal Institute of Diabetes and Endocrinology, Jinnah Hospital Lahore. Sixty-four HIV positive patients, both male and female, aged above 15 years were included in the study. HIV patients who had recently taken steroids, ketoconazole or rifampicin, determined on history, were excluded from the study. The data was collected on a structured proforma and analysis was performed in SPSS-21.0. Frequency and percentages for adrenal insufficiency and its characteristics were calculated. Chi-square test was used with p<0.05 as statistically significant. Results: In this study, 9 (14.06%) HIV patients were diagnosed with adrenal insufficiency, male to female ratio was 3.5:1 and AI was found statistically significantly associated with fatigue (p<0.008) and weight loss (p<0.001). Conclusion: Adrenal insufficiency was high among the patients with HIV, it was not gender specific but it was found to be associated with fatigue and weight loss. (author)

  9. Afraid to Start Because the Outcome is Uncertain?: Social Site Characterization as a Tool for Informing Public Engagement Efforts

    Science.gov (United States)

    Wade, S.; Greenberg, S.

    2009-01-01

    This paper introduces the concept of social site characterization as a parallel effort to technical site characterization to be used in evaluating and planning carbon dioxides capture and storage (CCS) projects. Social site characterization, much like technical site characterization, relies on a series of iterative investigations into public attitudes towards a CCS project and the factors that will shape those views. This paper also suggests ways it can be used to design approaches for actively engaging stakeholders and communities in the deployment of CCS projects. This work is informed by observing the site selection process for FutureGen and the implementation of research projects under the Regional Carbon Sequestration Partnership Program. ?? 2009 Elsevier Ltd. All rights reserved.

  10. Remote Sensing and Geographic Information System (GIS) Technologies for Natural Hazard Risk Site Detection

    International Nuclear Information System (INIS)

    Wenzel, H.

    2007-01-01

    Satellite imageries and digital elevation data of Turkey are investigated for detecting sites prone to natural hazards. Digital image processing methods used to enhance satellite data and to produce morphometric maps in order to contribute to the detection of causal factors related to landslides, local site conditions influencing and/or experiencing earthquake damage intensity or those of tsunami and storm surge hazard sites at the coasts

  11. Enhancing evidence informed policymaking in complex health systems: lessons from multi-site collaborative approaches.

    Science.gov (United States)

    Langlois, Etienne V; Becerril Montekio, Victor; Young, Taryn; Song, Kayla; Alcalde-Rabanal, Jacqueline; Tran, Nhan

    2016-03-17

    There is an increasing interest worldwide to ensure evidence-informed health policymaking as a means to improve health systems performance. There is a need to engage policymakers in collaborative approaches to generate and use knowledge in real world settings. To address this gap, we implemented two interventions based on iterative exchanges between researchers and policymakers/implementers. This article aims to reflect on the implementation and impact of these multi-site evidence-to-policy approaches implemented in low-resource settings. The first approach was implemented in Mexico and Nicaragua and focused on implementation research facilitated by communities of practice (CoP) among maternal health stakeholders. We conducted a process evaluation of the CoPs and assessed the professionals' abilities to acquire, analyse, adapt and apply research. The second approach, called the Policy BUilding Demand for evidence in Decision making through Interaction and Enhancing Skills (Policy BUDDIES), was implemented in South Africa and Cameroon. The intervention put forth a 'buddying' process to enhance demand and use of systematic reviews by sub-national policymakers. The Policy BUDDIES initiative was assessed using a mixed-methods realist evaluation design. In Mexico, the implementation research supported by CoPs triggered monitoring by local health organizations of the quality of maternal healthcare programs. Health programme personnel involved in CoPs in Mexico and Nicaragua reported improved capacities to identify and use evidence in solving implementation problems. In South Africa, Policy BUDDIES informed a policy framework for medication adherence for chronic diseases, including both HIV and non-communicable diseases. Policymakers engaged in the buddying process reported an enhanced recognition of the value of research, and greater demand for policy-relevant knowledge. The collaborative evidence-to-policy approaches underline the importance of iterations and continuity

  12. Predicting Greater Prairie-Chicken Lek Site Suitability to Inform Conservation Actions.

    Directory of Open Access Journals (Sweden)

    Torre J Hovick

    Full Text Available The demands of a growing human population dictates that expansion of energy infrastructure, roads, and other development frequently takes place in native rangelands. Particularly, transmission lines and roads commonly divide rural landscapes and increase fragmentation. This has direct and indirect consequences on native wildlife that can be mitigated through thoughtful planning and proactive approaches to identifying areas of high conservation priority. We used nine years (2003-2011 of Greater Prairie-Chicken (Tympanuchus cupido lek locations totaling 870 unique leks sites in Kansas and seven geographic information system (GIS layers describing land cover, topography, and anthropogenic structures to model habitat suitability across the state. The models obtained had low omission rates (0.81, indicating high model performance and reliability of predicted habitat suitability for Greater Prairie-Chickens. We found that elevation was the most influential in predicting lek locations, contributing three times more predictive power than any other variable. However, models were improved by the addition of land cover and anthropogenic features (transmission lines, roads, and oil and gas structures. Overall, our analysis provides a hierarchal understanding of Greater Prairie-Chicken habitat suitability that is broadly based on geomorphological features followed by land cover suitability. We found that when land features and vegetation cover are suitable for Greater Prairie-Chickens, fragmentation by anthropogenic sources such as roadways and transmission lines are a concern. Therefore, it is our recommendation that future human development in Kansas avoid areas that our models identified as highly suitable for Greater Prairie-Chickens and focus development on land cover types that are of lower conservation concern.

  13. Developing a secured social networking site using information security awareness techniques

    Directory of Open Access Journals (Sweden)

    Julius O. Okesola

    2014-11-01

    Full Text Available Background: Ever since social network sites (SNS became a global phenomenon in almost every industry, security has become a major concern to many SNS stakeholders. Several security techniques have been invented towards addressing SNS security, but information security awareness (ISA remains a critical point. Whilst very few users have used social circles and applications because of a lack of users’ awareness, the majority have found it difficult to determine the basis of categorising friends in a meaningful way for privacy and security policies settings. This has confirmed that technical control is just part of the security solutions and not necessarily a total solution. Changing human behaviour on SNSs is essential; hence the need for a privately enhanced ISA SNS. Objective: This article presented sOcialistOnline – a newly developed SNS, duly secured and platform independent with various ISA techniques fully implemented. Method: Following a detailed literature review of the related works, the SNS was developed on the basis of Object Oriented Programming (OOP approach, using PhP as the coding language with the MySQL database engine at the back end. Result: This study addressed the SNS requirements of privacy, security and services, and attributed them as the basis of architectural design for sOcialistOnline. SNS users are more aware of potential risk and the possible consequences of unsecured behaviours. Conclusion: ISA is focussed on the users who are often the greatest security risk on SNSs, regardless of technical securities implemented. Therefore SNSs are required to incorporate effective ISA into their platform and ensure users are motivated to embrace it.

  14. Testosterone replacement therapy and the internet: an assessment of providers' health-related web site information content.

    Science.gov (United States)

    Oberlin, Daniel T; Masson, Puneet; Brannigan, Robert E

    2015-04-01

    To compare how providers of testosterone replacement therapy (TRT) in large metropolitan cities promote androgen replacement on their patient-oriented Web sites. TRT provider Web sites were identified using Google search and the terms "Testosterone replacement" and the name of the 5 most populous US cities. These Web sites were assessed for (1) type or specialty of medical provider, (2) discussion of the benefits and risks of TRT, and (3) industry affiliations. In total, 75 Web sites were evaluated. Twenty-seven of the 75 clinics (36%) were directed by nonphysicians, 35 (47%) were overseen by nonurology or nonendocrine physicians, and only 13 (17%) were specialist managed. Fourteen of 75 (18.6%) Web sites disclosed industry relationships. Ninety-five percent of Web sites promoted the benefits of TRT including improved sex drive, cognitive improvement, increased muscle strength, and/or improved energy. Only 20 of 75 Web sites (26.6%) described any side effect of TRT. Web sites directed by specialists were twice as likely to discuss risks of TRT compared with nonspecialist providers (41% vs 20%; odds ratio = 2.77; P <.01). Nine of 75 (12%) of all Web sites actually refuted that TRT was associated with significant side effects. Urologists and endocrinologists are in the minority of providers promoting TRT on the Internet. Specialists are more likely to discuss risks associated with TRT although the majority of surveyed Web sites that promote TRT do not mention treatment risks. There is substantial variability in quality and quantity of information on provider Web sites, which may contribute to misinformation regarding this prevalent health issue. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Ping-pong champion with adrenal insufficiency

    Science.gov (United States)

    Arima, Hiroshi; Imamine, Rui; Oiso, Yutaka

    2009-01-01

    A 62-year-old Japanese man, a bronze medal winner in the World Championship of table tennis when in his 20s, was diagnosed with secondary adrenocortical insufficiency due to isolated adrenocorticotropic hormone (ACTH) deficiency, and steroid administration was started. About 1 year after the diagnosis, he took part in a table tennis championship which was open to those 40 years or older. He took 10 mg hydrocortisone after breakfast as usual, played 10 matches, each of which took 20–30 min, and won the championship in about 8 h. Since the man could not always win the gruelling competition even when in his 50s, it is suggested that extra steroid hormone is not necessary for patients with adrenocortical insufficiency due to ACTH deficiency in order to successfully engage in sports requiring such intensity and endurance. PMID:21686433

  16. Clinicoroentgenological diagnosis of chronic venous ovarian insufficiency

    International Nuclear Information System (INIS)

    Grakova, L.S.; Galkin, E.V.; Naumova, E.B.

    1989-01-01

    The paper is devoted to clinicoroentgenological correlations of venous renogonadal hemodynamics in 168 women of reproductive age (151 women with infertility, habitual abortion, disordered menstrual function and 17 patients without disorders of the reproductive tract). Clinicolaboratory investigation was followed by visceral and parietal flebography for the detection of a pathological venous reflux into the ovarian pampiniform plexus. Clinicoroentgenological semiotics of chronic venous ovarian insufficiency was analyzed. Infertility was shown to be the main clinical manifestation of ovarian varicocele

  17. Homeostatic responses to amino acid insufficiency

    Directory of Open Access Journals (Sweden)

    Tracy G. Anthony

    2015-09-01

    Full Text Available This article provides a brief overview describing how two key signaling pathways, namely the integrated stress response and the mammalian target of rapamycin complex 1, work together to facilitate cellular adaptation to dietary amino acid insufficiency. A deeper understanding of these mechanisms is leading to identification of novel targets which aid in disease treatments, improve stress recovery and increase health span through slowed aging and enhanced metabolic fitness.

  18. Diagnosis and management of pancreatic exocrine insufficiency.

    Science.gov (United States)

    Nikfarjam, Mehrdad; Wilson, Jeremy S; Smith, Ross C

    2017-08-21

    In 2015, the Australasian Pancreatic Club (APC) published the Australasian guidelines for the management of pancreatic exocrine insufficiency (http://pancreas.org.au/2016/01/pancreatic-exocrine-insufficiency-guidelines). Pancreatic exocrine insufficiency (PEI) occurs when normal digestion cannot be sustained due to insufficient pancreatic digestive enzyme activity. This may be related to a breakdown, at any point, in the pancreatic digestive chain: pancreatic stimulation; synthesis, release or transportation of pancreatic enzymes; or synchronisation of secretions to mix with ingested food. Main recommendations: The guidelines provide advice on diagnosis and management of PEI, noting the following: A high prevalence of PEI is seen in certain diseases and conditions, such as cystic fibrosis, acute and chronic pancreatitis, pancreatic cancer and pancreatic surgery. The main symptoms of PEI are steatorrhoea or diarrhoea, abdominal pain, bloating and weight loss. These symptoms are non-specific and often go undetected and untreated. PEI diagnosis is predominantly based on clinical findings and the presence of underlying disease. The likelihood of PEI in suspected patients has been categorised into three groups: definite, possible and unlikely. If left untreated, PEI may lead to complications related to fat malabsorption and malnutrition, and have an impact on quality of life. Pancreatic enzyme replacement therapy (PERT) remains the mainstay of PEI treatment with the recommended adult initial enzyme dose being 25 000-40 000 units of lipase per meal, titrating up to a maximum of 75 000-80 000 units of lipase per meal. Adjunct acid-suppressing therapy may be useful when patients still experience symptoms of PEI on high dose PERT. Nutritional management by an experienced dietitian is essential. Changes in management as a result of these guidelines: These are the first guidelines to classify PEI as being definite, possible or unlikely, and provide a diagnostic algorithm to

  19. Chronic Heroin Dependence Leading to Adrenal Insufficiency

    Directory of Open Access Journals (Sweden)

    Gautam Das

    2014-01-01

    Full Text Available Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.

  20. A systematic identification of species-specific protein succinylation sites using joint element features information

    Directory of Open Access Journals (Sweden)

    Hasan MM

    2017-08-01

    Full Text Available Md Mehedi Hasan,1 Mst Shamima Khatun,2 Md Nurul Haque Mollah,2 Cao Yong,3 Dianjing Guo1 1School of Life Sciences and the State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, New Territory, Hong Kong, People’s Republic of China; 2Laboratory of Bioinformatics, Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh; 3Department of Mechanical Engineering and Automation, Harbin Institute of Technology, Shenzhen Graduate School, Shenzhen, People’s Republic of China Abstract: Lysine succinylation, an important type of protein posttranslational modification, plays significant roles in many cellular processes. Accurate identification of succinylation sites can facilitate our understanding about the molecular mechanism and potential roles of lysine succinylation. However, even in well-studied systems, a majority of the succinylation sites remain undetected because the traditional experimental approaches to succinylation site identification are often costly, time-consuming, and laborious. In silico approach, on the other hand, is potentially an alternative strategy to predict succinylation substrates. In this paper, a novel computational predictor SuccinSite2.0 was developed for predicting generic and species-specific protein succinylation sites. This predictor takes the composition of profile-based amino acid and orthogonal binary features, which were used to train a random forest classifier. We demonstrated that the proposed SuccinSite2.0 predictor outperformed other currently existing implementations on a complementarily independent dataset. Furthermore, the important features that make visible contributions to species-specific and cross-species-specific prediction of protein succinylation site were analyzed. The proposed predictor is anticipated to be a useful computational resource for lysine succinylation site prediction. The integrated species-specific online tool of SuccinSite2.0 is publicly

  1. Pancreatic Exocrine Insufficiency in Pancreatic Cancer

    Directory of Open Access Journals (Sweden)

    Miroslav Vujasinovic

    2017-02-01

    Full Text Available Abstract: Cancer patients experience weight loss for a variety of reasons, commencing with the tumor’s metabolism (Warburg effect and proceeding via cachexia to loss of appetite. In pancreatic cancer, several other factors are involved, including a loss of appetite with a particular aversion to meat and the incapacity of the pancreatic gland to function normally when a tumor is present in the pancreatic head. Pancreatic exocrine insufficiency is characterized by a deficiency of the enzymes secreted from the pancreas due to the obstructive tumor, resulting in maldigestion. This, in turn, contributes to malnutrition, specifically a lack of fat-soluble vitamins, antioxidants, and other micronutrients. Patients with pancreatic cancer and pancreatic exocrine insufficiency have, overall, an extremely poor prognosis with regard to surgical outcome and overall survival. Therefore, it is crucial to be aware of the mechanisms involved in the disease, to be able to diagnose pancreatic exocrine insufficiency early on, and to treat malnutrition appropriately, for example, with pancreatic enzymes.

  2. PolyaPeak: Detecting Transcription Factor Binding Sites from ChIP-seq Using Peak Shape Information

    Science.gov (United States)

    Wu, Hao; Ji, Hongkai

    2014-01-01

    ChIP-seq is a powerful technology for detecting genomic regions where a protein of interest interacts with DNA. ChIP-seq data for mapping transcription factor binding sites (TFBSs) have a characteristic pattern: around each binding site, sequence reads aligned to the forward and reverse strands of the reference genome form two separate peaks shifted away from each other, and the true binding site is located in between these two peaks. While it has been shown previously that the accuracy and resolution of binding site detection can be improved by modeling the pattern, efficient methods are unavailable to fully utilize that information in TFBS detection procedure. We present PolyaPeak, a new method to improve TFBS detection by incorporating the peak shape information. PolyaPeak describes peak shapes using a flexible Pólya model. The shapes are automatically learnt from the data using Minorization-Maximization (MM) algorithm, then integrated with the read count information via a hierarchical model to distinguish true binding sites from background noises. Extensive real data analyses show that PolyaPeak is capable of robustly improving TFBS detection compared with existing methods. An R package is freely available. PMID:24608116

  3. Portal. Making a portal site. INIS Web Services and energy information sources

    International Nuclear Information System (INIS)

    Yonezawa, Minoru

    2001-01-01

    The International Nuclear Information System (INIS) provides links to useful nuclear related information sources in Internet by the name of 'INIS Web Services' and the Energy Technology Data Exchange (ETDE) also provides links to useful energy related information sources in Internet by the name of Energy Information Source'. This paper outlines these two services. (author)

  4. Information pertinent to the migration of radionuclides in ground water at the Nevada Test Site. Part 2: annotated bibliography

    International Nuclear Information System (INIS)

    Borg, I.Y.; Stone, R.; Levy, H.B.; Ramspott, L.D.

    1976-01-01

    Part 2 of UCRL-52078 consists of the bibliography and abstracts that were compiled in the course of searching the literature for information on the migration of radionuclides in groundwater at the Nevada Test Site. The bibliography also includes numerous references to work done at foreign nuclear centers or contracted to outside agencies by these same centers

  5. JEA's Code of Ethics for Advisers; and Sites for Additional Ethics Information.

    Science.gov (United States)

    Bowen, John

    1997-01-01

    Lists general principles that media advisers should follow, the 12 points agreed upon as the Journalism Education Association's (JEA) Code of Ethics for Advisers, and a list of Web sites that deal with journalism ethics. (PA)

  6. 77 FR 44675 - Agency Information Collection Activities; Submission for OMB Review; Comment Request: Site Visit...

    Science.gov (United States)

    2012-07-30

    ... Poverty (POP), Energy Training Partnership (ETP), State Energy Sector Partnership (SESP), and Health Care... penalty for failing to comply with a collection of information if the collection of information does not...

  7. Informing child welfare policy and practice: using knowledge discovery and data mining technology via a dynamic Web site.

    Science.gov (United States)

    Duncan, Dean F; Kum, Hye-Chung; Weigensberg, Elizabeth Caplick; Flair, Kimberly A; Stewart, C Joy

    2008-11-01

    Proper management and implementation of an effective child welfare agency requires the constant use of information about the experiences and outcomes of children involved in the system, emphasizing the need for comprehensive, timely, and accurate data. In the past 20 years, there have been many advances in technology that can maximize the potential of administrative data to promote better evaluation and management in the field of child welfare. Specifically, this article discusses the use of knowledge discovery and data mining (KDD), which makes it possible to create longitudinal data files from administrative data sources, extract valuable knowledge, and make the information available via a user-friendly public Web site. This article demonstrates a successful project in North Carolina where knowledge discovery and data mining technology was used to develop a comprehensive set of child welfare outcomes available through a public Web site to facilitate information sharing of child welfare data to improve policy and practice.

  8. Occupational health and safety issues in the informal economic segment of Pakistan: a survey of construction sites.

    Science.gov (United States)

    Ahmed, Ishfaq; Shaukat, Muhammad Zeeshan; Usman, Ahmad; Nawaz, Muhammad Musarrat; Nazir, Mian Sajid

    2018-06-01

    This research covers the current status of occupational health and safety (OHS)-related practices in the informal construction segment of Pakistan. Data were collected, through interviews, from 316 construction sites employing 3577 workers. The results of the study reveal that both employers and workers lack knowledge of OHS laws/standards and no practices of this nature are enacted at these construction sites. Alarmingly, work-related accidents, whenever they happen, are not given due attention and there is no formal injury-report system. The informal construction industry employs a huge portion of the informal workforce, and lack of OHS happens at tremendous human cost. These research findings may thus play their role in strengthening the case for reforms in the sector. This study, if properly utilized, may also enable employers of the sector by increasing their knowledge about OHS practices and, as a result, trying to offer safer environments for their workers.

  9. Web-site evaluation tools: a case study in reproductive health information

    NARCIS (Netherlands)

    Aslani, Azam; Pournik, Omid; Abu-Hanna, Ameen; Eslami, Saeid

    2014-01-01

    Internet forms an opportunity to inform, teach, and connect professionals and patients. However, much information on Internet is incomplete, inaccurate, or misleading, and not only in the medical domain. Because of the potential for damage from misleading and inaccurate health information, many

  10. Heavy metals distribution and risk assessment in soil from an informal E-waste recycling site in Lagos State, Nigeria.

    Science.gov (United States)

    Isimekhai, Khadijah A; Garelick, Hemda; Watt, John; Purchase, Diane

    2017-07-01

    Informal E-waste recycling can pose a risk to human health and the environment which this study endeavours to evaluate. The distribution of a number of heavy metals in soil from an informal recycling site in the largest market for used and new electronics and electrical equipment in West Africa was investigated. The potential bioavailability of heavy metals, extent of contamination, potential risk due to the recycling activities and impact of external factors such as rainfall were also assessed. The concentrations of all the heavy metals tested were higher in the area where burning of the waste occurred than at the control site, suggesting an impact of the recycling activities on the soil. The order of total metal concentrations was Cu > Pb > Zn > Mn > Ni > Sb > Cr > Cd for both the dry and wet seasons. The total concentrations of Cd, Cu, Mn, Ni and Zn were all significantly higher (p  Sb > Zn > Cu > Ni > Pb > Cr. When the risk was assessed using the Potential Ecological Risk Index (PERI), Cu was found to contribute the most to the potential ecological risk and Cd gave rise to the greatest concern due to its high toxic-response factor within the study site. Similarly, utilising the Risk Assessment Code (RAC) suggested that Cd posed the most risk in this site. This research establishes a high level of contamination in the study site and underscores the importance of applying the appropriate chemical speciation in risk assessment.

  11. Information literacy and social networking sites: challenges and stakes regarding teenagers’ uses

    Directory of Open Access Journals (Sweden)

    Karine AILLERIE

    2016-12-01

    Full Text Available Research has shown that information seeking can act as a motivation to use SNS. In this paper, we identify patterns of information uses of SNS among teenagers specifically.There is evidence to suggest that teenagers use SNS for information purposes both informally outside of the school environment and also as part of their academic studies. We explore three important implications of this phenomemon in terms of students’ information literacy: firstly, the evaluation and validation of information obtained via SNS; secondly, the significance of these practices for collaboration and other 21st century skills; and finally, the porosity of formal and informal learning contexts. We conclude by reflecting on the ways in which current IL models and teaching practices need to adapt to accommodation teenagers’ uses of SNS.

  12. Corrective Action Investigation Plan for Corrective Action Unit 573: Alpha Contaminated Sites, Nevada National Security Site, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Patrick

    2014-05-01

    Corrective Action Unit (CAU) 573 is located in Area 5 of the Nevada National Security Site, which is approximately 65 miles northwest of Las Vegas, Nevada. CAU 573 is a grouping of sites where there has been a suspected release of contamination associated with non-nuclear experiments and nuclear testing. This document describes the planned investigation of CAU 573, which comprises the following corrective action sites (CASs): • 05-23-02, GMX Alpha Contaminated Area • 05-45-01, Atmospheric Test Site - Hamilton These sites are being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives.

  13. Nasopharyngeal pushback in treatment of velopharyngeal insufficiency.

    Science.gov (United States)

    Smith, H W; Lee, K J

    1976-02-01

    We describe a new technique for extensive retropositioning of the soft palate for the treatment of velopharyngeal insufficiency. This technique is identified as a nasopharyngeal pushback, and has been used repeatedly in conjunction with both a Cronin nasal flap and a superiorly based pharyngeal flap when maximum retropositioning was needed. This procedure has been used for over ten years, each time obtaining an additional pushback distance equal to or greater than the distance achieved by freeling the soft palate from the posterior border of the hard palate.

  14. Various musculoskeletal manifestations of chronic renal insufficiency

    International Nuclear Information System (INIS)

    Lim, C.Y.; Ong, K.O.

    2013-01-01

    Musculoskeletal manifestations in chronic renal insufficiency are caused by complex bone metabolism alterations, now described under the umbrella term of chronic kidney disease mineral- and bone-related disorder (CKD-MBD), as well as iatrogenic processes related to renal replacement treatment. Radiological imaging remains the mainstay of disease assessment. This review aims to illustrate the radiological features of CKD-MBD, such as secondary hyperparathyroidism, osteomalacia, adynamic bone disease, soft-tissue calcifications; as well as features associated with renal replacement therapy, such as aluminium toxicity, secondary amyloidosis, destructive spondyloarthropathy, haemodialysis-related erosive arthropathy, tendon rupture, osteonecrosis, and infection

  15. Readability of online patient education materials for velopharyngeal insufficiency.

    Science.gov (United States)

    Xie, Deborah X; Wang, Ray Y; Chinnadurai, Sivakumar

    2018-01-01

    Evaluate the readability of online and mobile application health information about velopharyngeal insufficiency (VPI). Top website and mobile application results for search terms "velopharyngeal insufficiency", "velopharyngeal dysfunction", "VPI", and "VPD" were analyzed. Readability was determined using 10 algorithms with Readability Studio Professional Edition (Oleander Software Ltd; Vandalia, OH). Subgroup analysis was performed based on search term and article source - academic hospital, general online resource, peer-reviewed journal, or professional organization. 18 unique articles were identified. Overall mean reading grade level was a 12.89 ± 2.9. The highest reading level among these articles was 15.47-approximately the level of a college senior. Articles from "velopharyngeal dysfunction" had the highest mean reading level (13.73 ± 2.11), above "velopharyngeal insufficiency" (12.30 ± 1.56) and "VPI" (11.66 ± 1.70). Articles from peer-reviewed journals had the highest mean reading level (15.35 ± 2.79), while articles from academic hospitals had the lowest (12.81 ± 1.66). There were statistically significant differences in reading levels between the different search terms (P reading level guidelines, online patient education materials for VPI are disseminated with language too complex for most readers. There is also a lack of VPI-related mobile application data available for patients. Patients will benefit if future updates to websites and disseminated patient information are undertaken with health literacy in mind. Future studies will investigate patient comprehension of these materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Analyzing Patterns of Community Interest at a Legacy Mining Waste Site to Assess and Inform Environmental Health Literacy Efforts

    Science.gov (United States)

    Ramirez-Andreotta, Monica D.; Lothrop, Nathan; Wilkinson, Sarah T.; Root, Robert A.; Artiola, Janick F.; Klimecki, Walter; Loh, Miranda

    2015-01-01

    Understanding a community’s concerns and informational needs is crucial to conducting and improving environmental health research and literacy initiatives. We hypothesized that analysis of community inquiries over time at a legacy mining site would be an effective method for assessing environmental health literacy efforts and determining whether community concerns were thoroughly addressed. Through a qualitative analysis, we determined community concerns at the time of being listed as a Superfund site. We analyzed how community concerns changed from this starting point over the subsequent years, and whether: 1) communication materials produced by the USEPA and other media were aligned with community concerns; and 2) these changes demonstrated a progression of the community’s understanding resulting from community involvement and engaged research efforts. We observed that when the Superfund site was first listed, community members were most concerned with USEPA management, remediation, site-specific issues, health effects, and environmental monitoring efforts related to air/dust and water. Over the next five years, community inquiries shifted significantly to include exposure assessment and reduction methods and issues unrelated to the site, particularly the local public water supply and home water treatment systems. Such documentation of community inquiries over time at contaminated sites is a novel method to assess environmental health literacy efforts and determine whether community concerns were thoroughly addressed. PMID:27595054

  17. Site-characterization information using LANDSAT satellite and other remote-sensing data: integration of remote-sensing data with geographic information systems. A case study in Pennsylvania

    International Nuclear Information System (INIS)

    Campbell, W.J.; Imhoff, M.L.; Robinson, J.; Gunther, F.; Boyd, R.; Anuta, M.

    1983-06-01

    The utility and cost effectiveness of incorporating digitized aircraft and satellite remote sensing data into a geographic information system for facility siting and environmental impact assessments was evaluated. This research focused on the evaluation of several types of multisource remotely sensed data representing a variety of spectral band widths and spatial resolution. High resolution aircraft photography, Landsat MSS, and 7 band Thematic Mapper Simulator (TMS) data were acquired, analyzed, and evaluated for their suitability as input to an operational geographic information system (GIS). 78 references, 59 figures, 74 tables

  18. AIRMICS (U.S. Army Institute for Research in Management Information, Communications and Computer Sciences) Information Center Model Site Evaluation

    Science.gov (United States)

    1986-10-01

    34 syndrome . Five techniques for developing user self-sufficiency were discussed in-depth: (1) provide training at different proficiency levels, id provide...WY aba. 4 ’-a ’aba. @9 "a,.. I bJ~ V N- S ha. E-ii S ’a ’baa .4, .;y ’. ; . a.,. ~ ~ .: ;r YK’.- xYY I. r d’...da.4/ 4/ tq..ttf.%r./..v-./ - "cc~’ v,-r...data base, accessible through a user friendly interfaces, to correlate and deliver crime , traffic, vehicle, and personnel information to " / fixed and

  19. The role of historical operations information for supporting remedial investigation work at the former Harshaw Chemical Site

    International Nuclear Information System (INIS)

    Johnson, R.; Peterson, J.; Picel, K.; Kolhoff, A.; Devaughn, J.

    2008-01-01

    In the early stages of hazardous, toxic, and radioactive waste (HTRW) site investigations, basic record searches are performed to help direct the agencies investigating contaminated sites to areas of concern and to identify contaminants of interest (COI). Plans developed on the basis of this preliminary research alone are often incomplete and result in unexpected discoveries either while in the field investigating the site or after the reports have been written. Many of the sites investigated under the Formerly Utilized Sites Remedial Action program (FUSRAP) have complex histories that are slowly uncovered over the life of the project. Because of programmatic constraints, nuances of these sites are often discovered late in their programs and result in increased expenditures in order to fully characterize the site, perform a robust feasibility study, and recommend appropriate alternatives for remediation. By identifying resources for public records, classified records, historic aerial photographs, and other sources of site-specific historical information, a process can be established to optimize the collection of information and to develop efficient and complete project plans. In many cases, interviews with past site employees are very useful tools. In combining what is found in the records, observed on historic aerial photographs, and heard from former employees and family members, teams investigating these sites can begin to compile sound and more complete conceptual site models (CSMs). The former Harshaw Chemical Site (HCS) illustrates this discovery process. HCS is part of FUSRAP. Preliminary investigations by the US Department of Energy (DOE) in the 1970s provided an initial CSM of activities that had taken place that may have resulted in contamination. The remedial investigation (RI) conducted by the US Army Corps of Engineers (USACE) was designed around this CSM. The RI work, however, identified a number of site conditions that were unexpected, including new

  20. A NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency

    OpenAIRE

    Wu, X; Wang, B; Dong, Z; Zhou, S; Liu, Z; Shi, G; Cao, Y; Xu, Y

    2013-01-01

    Primary ovarian insufficiency (POI), or premature ovarian failure, is defined as the cessation of ovarian function before the age of 40. An insufficient ovarian follicle pool derived from primordial germ cells (PGCs) is an important cause of POI. Although the Nanos gene family is known to be required for PGC development and maintenance in diverse model organisms, the relevance of this information to human biology is not yet clear. In this study, we screened the coding regions of the NANOS1, N...

  1. Assessing the quality of websites providing information on multiple sclerosis: evaluating tools and comparing sites.

    Science.gov (United States)

    Harland, Juliet; Bath, Peter

    2007-09-01

    The quality of health information available on the Internet has proved difficult to assess objectively. The Internet's growing popularity as a source of health information, accompanied by the lack of regulation of websites, has resulted in research that has developed and tested tools to evaluate health website quality. However, only a few studies have tested the validity and reliability of these tools. There is a lack of consensus about appropriate indicators with which to operationalize the concept of quality health information. This study aimed to contribute to this research by testing the validity and reliability of existing tools, through their application to websites that provided information about multiple sclerosis. Furthermore, a specific tool for evaluating multiple sclerosis information was developed, contributing to the debate about suitable criteria for measuring the ;quality' of health information on the web.

  2. Information Re-Sharing on Social Network Sites in the Age of Fake News

    Directory of Open Access Journals (Sweden)

    Mehrdad Koohikamali

    2017-10-01

    This study has important practical implications for SNS users and providers alike. Ensuring that information available on SNS is of high quality is critical to maintaining a healthy user base. Findings: Results indicate that attitude toward using SNSs and intention to re-share infor-mation on SNSs is influenced by perceived information quality (enjoyment, rele-vance, and reliability. Also, risk-taking propensity and enjoyment influence the intention to re-share information on SNSs in a positive direction. Future Research: In the dynamic context of SNSs, the role played by quality of information is changing. Understanding changes in quality of information by conducting longitudinal studies and experiments and including the role of habits is necessary.

  3. Web-based recruitment: effects of information, organizational brand, and attitudes toward a Web site on applicant attraction.

    Science.gov (United States)

    Allen, David G; Mahto, Raj V; Otondo, Robert F

    2007-11-01

    Recruitment theory and research show that objective characteristics, subjective considerations, and critical contact send signals to prospective applicants about the organization and available opportunities. In the generating applicants phase of recruitment, critical contact may consist largely of interactions with recruitment sources (e.g., newspaper ads, job fairs, organization Web sites); however, research has yet to fully address how all 3 types of signaling mechanisms influence early job pursuit decisions in the context of organizational recruitment Web sites. Results based on data from 814 student participants searching actual organization Web sites support and extend signaling and brand equity theories by showing that job information (directly) and organization information (indirectly) are related to intentions to pursue employment when a priori perceptions of image are controlled. A priori organization image is related to pursuit intentions when subsequent information search is controlled, but organization familiarity is not, and attitudes about a recruitment source also influence attraction and partially mediate the effects of organization information. Theoretical and practical implications for recruitment are discussed. (c) 2007 APA

  4. Improving the web site's effectiveness by considering each page's temporal information

    NARCIS (Netherlands)

    Li, ZG; Sun, MT; Dunham, MH; Xiao, YQ; Dong, G; Tang, C; Wang, W

    2003-01-01

    Improving the effectiveness of a web site is always one of its owner's top concerns. By focusing on analyzing web users' visiting behavior, web mining researchers have developed a variety of helpful methods, based upon association rules, clustering, prediction and so on. However, we have found

  5. The interactive on-site inspection system: An information management system to support arms control inspections

    Energy Technology Data Exchange (ETDEWEB)

    DeLand, S.M.; Widney, T.W.; Horak, K.E.; Caudell, R.B.; Grose, E.M.

    1996-12-01

    The increasing use of on-site inspection (OSI) to meet the nation`s obligations with recently signed treaties requires the nation to manage a variety of inspection requirements. This document describes a prototype automated system to assist in the preparation and management of these inspections.

  6. Ethical considerations of using information obtained from online file sharing sites: The case of the piratebay

    NARCIS (Netherlands)

    van Wynsberghe, Amy Louise; van der Ham, Jeroen

    2015-01-01

    Purpose – The purpose of this paper is to develop a novel approach for the ethical analysis of data collected from an online file-sharing site known as The PirateBay. Since the creation of Napster back in the late 1990s for the sharing and distribution of MP3 files across the Internet, the

  7. Ethical considerations of using information obtained from online file sharing sites : The case of the piratebay

    NARCIS (Netherlands)

    van Wynsberghe, A.; van der Ham, J.

    2015-01-01

    Purpose – The purpose of this paper is to develop a novel approach for the ethical analysis of data collected from an online file-sharing site known as The PirateBay. Since the creation of Napster back in the late 1990s for the sharing and distribution of MP3 files across the Internet, the

  8. Manufacturing Menopause: An Analysis of the Portrayal of Menopause and Information Content on Pharmaceutical Web Sites

    Science.gov (United States)

    Charbonneau, Deborah Hile

    2010-01-01

    Consumer-targeted prescription drug advertising serves as an interesting lens through which we can examine the portrayal of menopause in online drug advertisements. The aim of this study was to explore the portrayal of menopause on web sites sponsored by pharmaceutical companies for hormone therapies (HT). To unravel this question, a qualitative…

  9. Inflammatory manifestations of experimental lymphatic insufficiency.

    Directory of Open Access Journals (Sweden)

    Raymond Tabibiazar

    2006-07-01

    Full Text Available BACKGROUND: Sustained lymph stagnation engenders a pathological response that is complex and not well characterized. Tissue inflammation in lymphedema may reflect either an active or passive consequence of impaired immune traffic. METHODS AND FINDINGS: We studied an experimental model of acute post-surgical lymphedema in the tails of female hairless, immunocompetent SKH-1 mice. We performed in vivo imaging of impaired immune traffic in experimental, murine acquired lymphatic insufficiency. We demonstrated impaired mobilization of immunocompetent cells from the lymphedematous region. These findings correlated with histopathological alterations and large-scale transcriptional profiling results. We found intense inflammatory changes in the dermis and the subdermis. The molecular pattern in the RNA extracted from the whole tissue was dominated by the upregulation of genes related to acute inflammation, immune response, complement activation, wound healing, fibrosis, and oxidative stress response. CONCLUSIONS: We have characterized a mouse model of acute, acquired lymphedema using in vivo functional imaging and histopathological correlation. The model closely simulates the volume response, histopathology, and lymphoscintigraphic characteristics of human acquired lymphedema, and the response is accompanied by an increase in the number and size of microlymphatic structures in the lymphedematous cutaneous tissues. Molecular characterization through clustering of genes with known functions provides insights into processes and signaling pathways that compose the acute tissue response to lymph stagnation. Further study of genes identified through this effort will continue to elucidate the molecular mechanisms and lead to potential therapeutic strategies for lymphatic vascular insufficiency.

  10. Applications of Augmented Reality in Informal Science Learning Sites: a Review

    Science.gov (United States)

    Goff, Eric E.; Mulvey, Kelly Lynn; Irvin, Matthew J.; Hartstone-Rose, Adam

    2018-05-01

    The importance of increasing interest in the STEM disciplines has been noted in a number of recent national reports. While many previous studies have focused on such efforts inside of the formal classroom, comparatively few have looked closely at informal learning environments. We investigate the innovative use of technology in informal learning by reviewing research on the incorporation of augmented reality (AR) at exhibit-based informal science education (ISE) settings in the literature. We report on the common STEM-focused topics that are covered by current AR applications for ISE learning, as well as the different devices used to support these applications. Additionally, we report on the prevalence of positive learning outcomes and engagement factors commonly associated with the use AR applications in informal environments. This review aims to foster continued development and implementation of AR technology in exhibit-based ISE settings by informing the community of recent findings and promoting additional rigorous research for the future.

  11. A study of methodology and its applications for the evaluation of total system performance which considered the site-information and the design-information

    International Nuclear Information System (INIS)

    Inagaki, Manabu; Ebina, Takanori

    2008-01-01

    The step-by-step approach which chooses detailed investigation area(s) from the preliminary investigations area(s) in the volunteer sites is adopted on the high-level radioactive waste disposal in JAPAN. It's requested at the stage of chooses detailed investigation area that there are few fears that surf zone and groundwater stream exert bad influence on disposal facility as well as stability of the geological environment. In order to evaluate influence of groundwater stream, it is necessary to evaluate of total performance of disposal system with limited information from preliminary investigations and several design options which have been assumed on the generic geological environment. For a rational procedure of total system evaluation, it is essential to arrange of known information of the former performance evaluation, and so, when same part of those information was changed, we become able to pick a scenario, models, parameters with a possibility which changes out by tracing these information. In this study, as a first step, we carried out make a methodology to structure a flow of a series of information from a geological survey result in detail and until performance evaluation. We tried to make a structuralization of known information by base on this methodology. And, we discussed realistic performance of over-pack by tracing this structured information. (author)

  12. An Extended VIKOR-Based Approach for Pumped Hydro Energy Storage Plant Site Selection with Heterogeneous Information

    Directory of Open Access Journals (Sweden)

    Yunna Wu

    2017-08-01

    Full Text Available The selection of a desirable site for constructing a pumped hydro energy storage plant (PHESP plays a vital important role in the whole life cycle. However, little research has been done on the site selection of PHESP, which affects the rapid development of PHESP. Therefore, this paper aims to select the most ideal PHESP site from numerous candidate alternatives using the multi-criteria decision-making (MCDM technique. Firstly, a comprehensive evaluation criteria system is established for the first time. Then, considering quantitative and qualitative criteria coexist in this system, multiple types of representations, including crisp numerical values (CNVs, triangular intuitionistic fuzzy numbers (TIFNs, and 2-dimension uncertain linguistic variables (2DULVs, are employed to deal with heterogeneous criteria information. To determine the weight of criteria and fully take the preference of the decision makers (DMs into account, the analytic hierarchy process (AHP method is applied for criteria weighting. After that, an extended Vlsekriterijumska Optimizacija I Kompromisno Resenje (VIKOR method is utilized to provide compromise solutions for the PHESP site considering such heterogeneous information. At last, the proposed model is then applied in a case study of Zhejiang province, China to illustrate its practicality and efficiency. The result shows the Changlongshan should be selected as the optimal PHESP.

  13. Information for consideration in reviewing groundwater protection plans for uranium mill tailings sites

    International Nuclear Information System (INIS)

    Thorne, P.D.

    1992-05-01

    Guidelines and acceptance criteria were developed for reviewing certain aspects of groundwater protection plans for uranium mill tailing sites. The aspects covered include: (1) leaching and long-term releases of hazardous and radioactive constituents from tailings and other contaminated materials, (2) attenuation of hazardous and radioactive constituents in groundwater under saturated and unsaturated conditions, (3) design and implementation of groundwater monitoring programs, (4) design and construction of groundwater protection barriers, and (5) efficiency and effectiveness of groundwater cleanup programs. The objective of these guidelines is to assist the US Nuclear Regulatory Commission staff in reviewing Remedial Action Plans for inactive waste sites and licensing application documents for active commercial uranium and thorium mills

  14. Nurses in need of additional support: web sites offering information in eldercare nursing environments.

    Science.gov (United States)

    Matusitz, Jonathan; Breen, Gerald-Mark; Marathe, Shriram S; Wan, Thomas T H

    2010-01-01

    Studies have shown the usefulness of telemedicine and telecare in multiple settings. One form of telemedicine is e-health. Residents of nursing homes are a unique population that may significantly benefit from the e-health resources available to their caregivers. E-health Web sites appear to be viable, feasible, and timely interventional methods to provide the additional knowledge and support practitioners in these settings may need to provide preventative, reactive, and remedial care for frail residents.

  15. Hanford Site Air Operating Permit Application - Supplemental Information (Supplement 1, Volumes 1 thru 3)

    International Nuclear Information System (INIS)

    CURN, B.L.

    2000-01-01

    This report documents radionuclide air emissions from the Hanford Site in 1998 and the resulting effective dose equivalent to the maximally exposed individual (MEI) member of the public. The report has been prepared in accordance with the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (40 CFR 61), Subpart H: ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities,'' and with the Washington Administrative Code Chapter 246247, Radiation Protection - Air Emissions. The federal regulations in 40 CFR 61, Subpart H, require the measurement and reporting of radionuclides emitted from Department of Energy facilities and the resulting offsite dose from those emissions. A standard of 10 mrem/yr effective dose equivalent (EDE) is imposed on them. The EDE to the MEI due to routine emissions in 1998 from Hanford Site point sources was 1.3 E-02 mrem (1.3 E-04 mSv). which is 0.13 percent of the federal standard. Chapter 246-247 of the Washington Administrative Code (WAC) requires the reporting of radionuclide emissions from all Department of Energy Hanford Site sources. The state has adopted into these regulations the 40 CFR 61 standard of 10 mrem/yr EDE. The EDE to the MEI attributable to diffuse and fugitive radionuclide air emissions from the Hanford Site in 1998 was 2.5 E-02 mrem (2.S E-04 mSv). This dose added to the dose from point sources gives a total for all sources of 3.8 E-02 mrem/yr (3.8 E-04 mSv) EDE. which is 0.38 percent of the 10 mrem/yr standard. An unplanned release on August 26, 1998, in the 300 Area of the Hanford Site resulted in a potential dose of 4.1 E-02 mrem to a hypothetical individual at the nearest point of public access to that area. This hypothetical individual was not the MEI since the wind direction on the day of the release was away from the MEI residence. The potential dose from the unplanned event

  16. Genetics Home Reference: fragile X-associated primary ovarian insufficiency

    Science.gov (United States)

    ... Share: Email Facebook Twitter Home Health Conditions FXPOI Fragile X-associated primary ovarian insufficiency Printable PDF Open All ... Javascript to view the expand/collapse boxes. Description Fragile X-associated primary ovarian insufficiency ( FXPOI ) is a condition ...

  17. Abstraction of information in repository performance assessments. Examples from the SKI project Site-94

    International Nuclear Information System (INIS)

    Dverstorp, B.; Andersson, J.

    1995-01-01

    Performance Assessment of a nuclear waste repository implies an analysis of a complex system with many interacting processes. Even if some of these processes may be known to large detail, problems arise when combining all information, and means of abstracting information from complex detailed models into models that couple different processes are needed. Clearly, one of the major objectives of performance assessment, to calculate doses or other performance indicators, implies an enormous abstraction of information compared to all information that is used as input. Other problems are that the knowledge of different parts or processes is strongly variable and adjustments, interpretations, are needed when combining models from different disciplines. In addition, people as well as computers, even today, always have a limited capacity to process information and choices have to be made. However, because abstraction of information clearly is unavoidable in performance assessment the validity of choices made, always need to be scrutinized and judgements made need to be updated in an iterative process

  18. Insufficient incentives for investment in electricity generations

    Energy Technology Data Exchange (ETDEWEB)

    Neuhoff, K. [Cambridge University (United Kingdom). Dept. of Applied Economics; De Vries, L. [Delft University of Technology (Netherlands). Faculty of Technology, Policy and Management

    2004-12-01

    In theory, competitive electricity markets provide incentives for efficient investment in generation capacity. We show that if consumers and investors are risk averse, investment is efficient only if investors in generation capacity can sign long-term contracts with consumers. Otherwise the uncovered price risk increases financing costs, reduces equilibrium investment levels, distorts technology choice towards less capital-intensive generation and reduces consumer utility. We observe insufficient levels of long-term contracts in existing markets, possibly because retail companies are not credible counter-parties if their final customers can switch easily between them. With a consumer franchise, retailers can sign long-term contracts, but this solution comes at the expense of retail competition. Alternative capacity mechanisms to stimulate investment are discussed. (author)

  19. Ultrasound assessment of great saphenous vein insufficiency

    Directory of Open Access Journals (Sweden)

    Chander RK

    2015-06-01

    Full Text Available Rajiv K Chander,1 Thomas S Monahan1,2 1Section of Vascular Surgery, Department of Surgery, University of Maryland School of Medicine, 2Department of Surgery, Baltimore Veterans Affairs Medical Center, Baltimore, MD, USA Abstract: Duplex ultrasonography is the ideal modality to assess great saphenous vein insufficiency. Duplex ultrasonography incorporates both gray scale images to delineate anatomy and color-Doppler imaging that visualizes the flow of blood in a structure. Assessment of great saphenous vein requires definition of the anatomy, augmentation of flow, evaluation for both superficial and deep vein thrombosis, and determining the presence of reflux. Currently, evolution in the treatment of reflux also relies on ultrasound for the treatment of the disease. Understanding the utilization of the ultrasound for the diagnosis and treatment of greater saphenous vein reflux is important for practitioners treating reflux disease. Keywords: duplex ultrasonography, small saphenous vein 

  20. Fractures due to insufficient pelvic girdle

    International Nuclear Information System (INIS)

    Garcia Aguayo, F.J.; Martinez Almagro, A.

    1995-01-01

    Eleven cases are presented of postmenopausal women with a total of 37 fractures due to insufficient pelvic girdle: 15 located in sacrum, ten in the pubic rami, four in ilium proximal to the sacroiliac joint, three in iliac fossa, two in iliac tuberosity and three in the public body. Eight of the patients were diagnosed over a period of six years when seeking medical attention for bone pain. The other three were diagnosed retrospectively among a group of 33 cancer patients (the majority having having breast cancer) who presented positive pelvic radionuclide bone scan. CT was superior to conventional radiology in detecting fractures of this type, especially those of sacrum and ilium. Radionuclide bone scan was highly sensitive but its specificity was low, requiring back-up radiology and above all CT to establish the differential diagnosis with respect to other types of lesions, especially metastases. (Author) 14 refs

  1. Developing site-specific interactive environmental management tools: An exciting method of communicating training, procedures, and other information

    Energy Technology Data Exchange (ETDEWEB)

    Jaeckels, J.M.

    1999-07-01

    Environmental managers are faced with numerous programs that must be communicated throughout their organizations. Among these are regulatory training programs, internal environmental policy, regulatory guidance/procedures and internal guidance/procedures. Traditional methods of delivering this type of information are typically confined to written materials and classroom training. There are many challenges faced by environmental managers with these traditional approaches including: determining if recipients of written plans or procedures are reading and comprehending the information; scheduling training sessions to reach all affected people across multiple schedules/shifts; and maintaining adequate training records. In addition, current trends toward performance-based or competency-based training requires a more consistent method of measuring and documenting performance. The use of interactive computer applications to present training or procedural information is a new and exciting tool for delivering environmental information to employees. Site-specific pictures, text, sound, and even video can be combined with multimedia software to create informative and highly interactive applications. Some of the applications that can be produced include integrated environmental training, educational pieces, and interactive environmental procedures. They can be executed from a CD-ROM, hard drive, network or a company Intranet. Collectively, the authors refer to these as interactive environmental management tools (IEMTs). This paper focuses on site-specific, interactive training as an example of an IEMT. Interactive training not only delivers a highly effective message, but can also be designed to focus on site-specific environmental issues that are unique to each company. Interactive training also lends itself well to automated record keeping functions and to reaching all affected employees.

  2. Acceptance criteria for the physical protection upgrade rule requirements for fixed sites. Information guide

    International Nuclear Information System (INIS)

    Dwyer, P.

    1980-09-01

    This document has been developed as a tool to assist in providing consistent evaluation of upgraded physical security plans submitted in response to the Physical Protection Upgrade Rule, effective March 25, 1980. It presents a means for assuring licensee compliance with every regulatory requirement of particular significance to the protection of the public health and safety. Acceptance criteria are included to determine the extent to which each licensee meets the regulatory requirements. The format parallels Regulatory Guide 5.52, Standard Format and Content of a Licensee Physical Protection Plan for Strategic Special Nuclear Material at Fixed Sites

  3. Figures and information on nuclear safety and radiation protection on the Tricastin AREVA site

    International Nuclear Information System (INIS)

    2010-01-01

    This report presents and briefly comments figures concerning the environment (water consumption, greenhouse gas emissions, liquid releases in a canal, radioactive and hazardous industrial wastes), radiological impact and radiation protection (computed dose for a reference group, computed maximum dose for the reference group, radiological exposures of workers), nuclear safety (number of events, controls and audits), production (quantities of various materials) and transport (flows of radioactive products) for the whole Tricastin site for which only some general data are indicated, and more precisely the various installations and establishments it comprises: AREVA NC Pierrelatte, COMURHEX Pierrelatte, EURODIF Production, FBFC Pierrelatte, SET, SOCATRI

  4. Introduction and user's information for the fixed site physical protection upgrade rule guidance compendium

    International Nuclear Information System (INIS)

    Evans, L.J. Jr.; Allen, T.

    1980-06-01

    Licensees at fixed sites who possess, use, process, or handle strategic special nuclear material are required to design a physical security system to protect this material. This report suggests an orderly process for using guidance, with special emphasis on two regulatory guides and two NUREG series documents that comprise a compendium, to aid in the design of a physical security system that meets the requirements of the final Physical Protection Upgrade Rule. The rule was published November 28, 1979 (44 FR 68184), and became effective March 25, 1980

  5. Using Geographic Information Systems to Determine Site Suitability for a Low-Level Radioactive Waste Storage Facility.

    Science.gov (United States)

    Wilson, Charles A; Matthews, Kennith; Pulsipher, Allan; Wang, Wei-Hsung

    2016-02-01

    Radioactive waste is an inevitable product of using radioactive material in education and research activities, medical applications, energy generation, and weapons production. Low-level radioactive waste (LLW) makes up a majority of the radioactive waste produced in the United States. In 2010, over two million cubic feet of LLW were shipped to disposal sites. Despite efforts from several states and compacts as well as from private industry, the options for proper disposal of LLW remain limited. New methods for quickly identifying potential storage locations could alleviate current challenges and eventually provide additional sites and allow for adequate regional disposal of LLW. Furthermore, these methods need to be designed so that they are easily communicated to the public. A Geographic Information Systems (GIS) based method was developed to determine suitability of potential LLW disposal (or storage) sites. Criteria and other parameters of suitability were based on the Code of Federal Regulation (CFR) requirements as well as supporting literature and reports. The resultant method was used to assess areas suitable for further evaluation as prospective disposal sites in Louisiana. Criteria were derived from the 10 minimum requirements in 10 CFR Part 61.50, the Nuclear Regulatory Commission's Regulatory Guide 0902, and studies at existing disposal sites. A suitability formula was developed permitting the use of weighting factors and normalization of all criteria. Data were compiled into GIS data sets and analyzed on a cell grid of approximately 14,000 cells (covering 181,300 square kilometers) using the suitability formula. Requirements were analyzed for each cell using multiple criteria/sub-criteria as well as surrogates for unavailable datasets. Additional criteria were also added when appropriate. The method designed in this project proved to be sufficient for initial screening tests in determining the most suitable areas for prospective disposal (or storage

  6. Geographic Information System (GIS) Applications at a Multi-Site Community College.

    Science.gov (United States)

    Pottle, Laura

    This report presents the Front Range Community College (FRCC) (Colorado) Office of Institutional Research's recent expansion of its data analysis and reporting capabilities to include a geographic information system (GIS). Utilizing ArcView GIS software, the college is better able to visualize institutional and environmental data. They have…

  7. Competitor timing information affects nest site selection in a migratory bird

    NARCIS (Netherlands)

    Samplonius, Jelmer Menno

    2016-01-01

    INTRODUCTION The costs of competition should lead to competitor avoidance. However, science has shown that animals may prefer settling near competitors to benefit from information about habitat quality. High quality habitat may translate to higher densities and reproductive success, but also to

  8. International use of an academic nephrology World Wide Web site: from medical information resource to business tool.

    Science.gov (United States)

    Abbott, Kevin C; Oliver, David K; Boal, Thomas R; Gadiyak, Grigorii; Boocks, Carl; Yuan, Christina M; Welch, Paul G; Poropatich, Ronald K

    2002-04-01

    Studies of the use of the World Wide Web to obtain medical knowledge have largely focused on patients. In particular, neither the international use of academic nephrology World Wide Web sites (websites) as primary information sources nor the use of search engines (and search strategies) to obtain medical information have been described. Visits ("hits") to the Walter Reed Army Medical Center (WRAMC) Nephrology Service website from April 30, 2000, to March 14, 2001, were analyzed for the location of originating source using Webtrends, and search engines (Google, Lycos, etc.) were analyzed manually for search strategies used. From April 30, 2000 to March 14, 2001, the WRAMC Nephrology Service website received 1,007,103 hits and 12,175 visits. These visits were from 33 different countries, and the most frequent regions were Western Europe, Asia, Australia, the Middle East, Pacific Islands, and South America. The most frequent organization using the site was the military Internet system, followed by America Online and automated search programs of online search engines, most commonly Google. The online lecture series was the most frequently visited section of the website. Search strategies used in search engines were extremely technical. The use of "robots" by standard Internet search engines to locate websites, which may be blocked by mandatory registration, has allowed users worldwide to access the WRAMC Nephrology Service website to answer very technical questions. This suggests that it is being used as an alternative to other primary sources of medical information and that the use of mandatory registration may hinder users from finding valuable sites. With current Internet technology, even a single service can become a worldwide information resource without sacrificing its primary customers.

  9. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering.

    Science.gov (United States)

    Novitsky, Vlad; Moyo, Sikhulile; Lei, Quanhong; DeGruttola, Victor; Essex, M

    2015-05-01

    To improve the methodology of HIV cluster analysis, we addressed how analysis of HIV clustering is associated with parameters that can affect the outcome of viral clustering. The extent of HIV clustering and tree certainty was compared between 401 HIV-1C near full-length genome sequences and subgenomic regions retrieved from the LANL HIV Database. Sliding window analysis was based on 99 windows of 1,000 bp and 45 windows of 2,000 bp. Potential associations between the extent of HIV clustering and sequence length and the number of variable and informative sites were evaluated. The near full-length genome HIV sequences showed the highest extent of HIV clustering and the highest tree certainty. At the bootstrap threshold of 0.80 in maximum likelihood (ML) analysis, 58.9% of near full-length HIV-1C sequences but only 15.5% of partial pol sequences (ViroSeq) were found in clusters. Among HIV-1 structural genes, pol showed the highest extent of clustering (38.9% at a bootstrap threshold of 0.80), although it was significantly lower than in the near full-length genome sequences. The extent of HIV clustering was significantly higher for sliding windows of 2,000 bp than 1,000 bp. We found a strong association between the sequence length and proportion of HIV sequences in clusters, and a moderate association between the number of variable and informative sites and the proportion of HIV sequences in clusters. In HIV cluster analysis, the extent of detectable HIV clustering is directly associated with the length of viral sequences used, as well as the number of variable and informative sites. Near full-length genome sequences could provide the most informative HIV cluster analysis. Selected subgenomic regions with a high extent of HIV clustering and high tree certainty could also be considered as a second choice.

  10. Count Your Calories and Share Them: Health Benefits of Sharing mHealth Information on Social Networking Sites.

    Science.gov (United States)

    Oeldorf-Hirsch, Anne; High, Andrew C; Christensen, John L

    2018-04-23

    This study investigates the relationship between sharing tracked mobile health (mHealth) information online, supportive communication, feedback, and health behavior. Based on the Integrated Theory of mHealth, our model asserts that sharing tracked health information on social networking sites benefits users' perceptions of their health because of the supportive communication they gain from members of their online social networks and that the amount of feedback people receive moderates these associations. Users of mHealth apps (N = 511) completed an online survey, and results revealed that both sharing tracked health information and receiving feedback from an online social network were positively associated with supportive communication. Network support both corresponded with improved health behavior and mediated the association between sharing health information and users' health behavior. As users received greater amounts of feedback from their online social networks, however, the association between sharing tracked health information and health behavior decreased. Theoretical implications for sharing tracked health information and practical implications for using mHealth apps are discussed.

  11. Semantic Building Information Modeling and high definition surveys for Cultural Heritage sites

    Directory of Open Access Journals (Sweden)

    Simone Garagnani

    2012-11-01

    Full Text Available In recent years, digital technology devoted to the building design has experienced significant advancements allowing to reach, by means of the Building Information Modeling, those goals only imagined since the mid-Seventies of the last century. The BIM process, bearer of several advantages for actors and designers who implement it in their workflow, may be employed even in various case studies related to some interventions on the existing architectural Cultural Heritage. The semantics typical of the classical architecture, so pervasive in the European urban landscape, as well as the Modern or Contemporary architecture features, coincide with the self-conscious structure made of “smart objects” proper of BIM, which proves to be an effective system to document component relationships. However, the translation of existing buildings geometric information, acquired using the common techniques of laser scanning and digital photogrammetry, into BIM objects, is still a critical process that this paper aims to investigate, describing possible methods and approaches.

  12. International data- and information exchange for off-site emergency management - Where to go?

    International Nuclear Information System (INIS)

    Hoebler, C.; Hable, K.; Baig, S.; Zaehringer, M.

    2004-01-01

    The Communication and exchange of views and opinions between decision makers and their advisers is crucial for coherent crisis management. As a vision, the concept of a 'Virtual Round Table' is proposed. It stands for the dedication of all accountable authorities to cross border cooperation and should provide a comprehensive technical infrastructure enabling decision makers and experts to communicate with their colleagues in neighbouring countries as if they were sitting at the same table. Organisational arrangements must be in place for coordinating decisions. The technical infrastructure should comprise modern communication technologies such as video conferencing and a 'Common Information Board', which presents all relevant information and documents in a structured way, manages alerting, decision journaling, data distribution and access control. In order to achieve this goal in an evolutionary approach, existing procedures of good practice are analysed and helpful features are identified. (authors)

  13. Competitor timing information affects nest site selection in a migratory bird

    OpenAIRE

    Samplonius, Jelmer Menno

    2016-01-01

    INTRODUCTION The costs of competition should lead to competitor avoidance. However, science has shown that animals may prefer settling near competitors to benefit from information about habitat quality. High quality habitat may translate to higher densities and reproductive success, but also to earlier reproductive timing. The former two have been studied as social cues, but competitor phenology has not. Climate change advances phenologies across trophic levels, so it is key to understand how...

  14. Visitor centres at nuclear facility sites how are they organized: what information do they provide

    International Nuclear Information System (INIS)

    Sorin, F.

    1993-01-01

    A large proportion of visitors consists in school children. The centre receives an average of 12 000 visitors a year. It regularly advertises its services through information campaigns and sometimes pays for advertising. Not a target for anti-nuclear demonstrations, it may receive some support from local authorities. Designed for the lay public, the Centre gives out concise and condensed information relating in equal measure to the nuclear power plant to which it is attached and nuclear energy in general (mentioning other applications of nuclear power and other energy sources). The information given is a neutral account of the facts rather than arguments justifying and promoting the use of nuclear energy. These Visitor Centres can be considered as an essential element in educating public opinion about nuclear energy. Furthermore, beyond the nuclear debate properly so-called, these Visitor Centres, together with science and technology museums, constitute one of the first vehicles in the world for disseminating scientific and technical knowledge to the general public

  15. Preliminary Information on the Vertebrate Fauna (Animalia: Vertebrata of the NATURA2000 Site “Rice Fields Tsalapitsa” (Bulgaria

    Directory of Open Access Journals (Sweden)

    Ivayla L. Klimentova

    2011-12-01

    Full Text Available The study was carried out by tree visits in different areas of the Natura 2000 site “Rice Fields Tsalapitsa” BG 0002086 (West of Plovdiv city, near village of Tsalapitsa. Our preliminary research showed that in the area vertebrates with high conservation status occurred included in the Bulgarian Bidiversity Act, Appendix II and III, Appendix II of the Bern convention, Natura 2000 species list, the Bonn convention, Appendix II, the Convention of the International Trade of Endangered Species, and the list of the International Union for Conservation of the Nature. This information will help in future preparation of the management plan of the Natura 2000 site and showed the need of studies focused on such areas which will help undertaking adequate measures for their proper way of conservation.

  16. Determining Home Range and Preferred Habitat of Feral Horses on the Nevada National Security Site Using Geographic Information Systems

    Energy Technology Data Exchange (ETDEWEB)

    Burns, Ashley V. [Univ. of Denver, CO (United States)

    2014-05-30

    Feral horses (Equus caballus) are free-roaming descendants of domesticated horses and legally protected by the Wild and Free-Roaming Horses and Burros Act of 1971, which mandates how feral horses and burros should be managed and protected on federal lands. Using a geographic information system to determine the home range and suitable habitat of feral horses on the federally managed Nevada National Security Site can enable wildlife biologists in making best management practice recommendations. Home range was estimated at 88.1 square kilometers. Site suitability was calculated for elevation, forage, slope, water presence and horse observations. These variables were combined in successive iterations into one polygon. Suitability rankings established that 85 square kilometers are most suitable habitat, with 2,052 square kilometers of good habitat 1,252 square kilometers of fair habitat and 122 square kilometers of least suitable habitat.

  17. Pheromonal Cues Deposited by Mated Females Convey Social Information about Egg-Laying Sites in Drosophila Melanogaster.

    Science.gov (United States)

    Duménil, Claire; Woud, David; Pinto, Francesco; Alkema, Jeroen T; Jansen, Ilse; Van Der Geest, Anne M; Roessingh, Sanne; Billeter, Jean-Christophe

    2016-03-01

    Individuals can make choices based on information learned from others, a phenomenon called social learning. How observers differentiate between which individual they should or should not learn from is, however, poorly understood. Here, we showed that Drosophila melanogaster females can influence the choice of egg-laying site of other females through pheromonal marking. Mated females mark territories of high quality food by ejecting surplus male sperm containing the aggregation pheromone cis-11-vaccenyl acetate (cVA) and, in addition, deposit several sex- and species-specific cuticular hydrocarbon (CHC) pheromones. These pheromonal cues affect the choices of other females, which respond by preferentially laying eggs on the marked food. This system benefits both senders and responders, as communal egg laying increases offspring survival. Virgin females, however, do not elicit a change in the egg-laying decision of mated females, even when food has been supplemented with ejected sperm from mated females, thus indicating the necessity for additional cues. Genetic ablation of either a female's CHC pheromones or those of their mate results in loss of ability of mated females to attract other females. We conclude that mated females use a pheromonal marking system, comprising cVA acquired from male ejaculate with sex- and species-specific CHCs produced by both mates, to indicate egg-laying sites. This system ensures information reliability because mated, but not virgin, females have both the ability to generate the pheromone blend that attracts other flies to those sites and a direct interest in egg-laying site quality.

  18. Insufficient sleep in adolescents: causes and consequences.

    Science.gov (United States)

    Owens, Judith A; Weiss, Miriam R

    2017-08-01

    Insufficient sleep poses an important and complicated set of health risks in the adolescent population. Not only is deficient sleep (defined as both sleep duration inadequate to meet sleep needs and sleep timing misaligned with the body's circadian rhythms) at epidemic levels in this population, but the contributing factors are both complex and numerous and there are a myriad of negative physical and mental health, safety and performance consequences. Causes of inadequate sleep identified in this population include internal biological processes such as the normal shift (delay) in circadian rhythm that occurs in association with puberty and a developmentally-based slowing of the "sleep drive", and external factors including extracurricular activities, excessive homework load, evening use of electronic media, caffeine intake and early school start times. Consequences range from inattentiveness, reduction in executive functioning and poor academic performance to increased risk of obesity and cardio-metabolic dysfunction, mood disturbances which include increased suicidal ideation, a higher risk of engaging in health risk behaviors such as alcohol and substance use, and increased rates of car crashes, occupational injuries and sports-related injuries. In response to these concerns, a number of promising measures have been proposed to reduce the burden of adolescent sleep loss, including healthy sleep education for students and families, and later school start times to allow adolescents to obtain sufficient and appropriately-timed sleep.

  19. Surgical management of traumatic tricuspid insufficiency.

    Science.gov (United States)

    Zhang, Zhiqi; Yin, Kanhua; Dong, Lili; Sun, Yongxin; Guo, Changfa; Lin, Yi; Wang, Chunsheng

    2017-06-01

    This study reviews our experience with traumatic tricuspid insufficiency (TTI) following blunt chest trauma. From January 2010 to June 2016, 10 patients (nine males, mean age 49.0 ± 12.4 years) underwent surgical treatment of TTI following blunt chest trauma. The mean intervals between trauma and diagnosis and between trauma and surgery were 74.1 and 81.8 months, respectively. Preoperatively, all patients exhibited severe tricuspid regurgitation. Five patients underwent tricuspid valve repair, and the remaining patients underwent valve replacement. The mean follow-up duration (with echocardiography) was 29.7 months. There was no early or late death. Seven patients had anterior chordal rupture, two patients had anterior papillary muscle rupture, and one patient had both anterior chordal and anterior leaflet rupture. The median postoperative intensive care unit and hospital stays were 1 and 6 days, respectively. There were no severe postoperative complications. During follow-up, four patients exhibited trivial to mild tricuspid regurgitation, and the remaining six patients exhibited no regurgitation. Surgical treatment of TTI via either valve repair or replacement can be performed with low perioperative morbidity and mortality. Early surgery is recommended for achieving a successful valve repair and preserving right ventricular function. © 2017 Wiley Periodicals, Inc.

  20. The Role and Value of Dialogue Events as Sites of Informal Science Learning

    DEFF Research Database (Denmark)

    Lehr, Jane L.; McCallie, Ellen; Davies, Sarah Rachael

    2007-01-01

    and staging of adult-focused, face-to-face forums that bring scien- tific and technical experts, social scientists, and policy-makers into discussion with members of the public about contemporary scientific and socioscientific issues related to the development and application of science and technology......In the past five years, informal science institutions (ISIs), science communication, advocacy and citizen action groups, funding organizations, and policy-makers in the UK and the USA have become increasingly involved in efforts to promote increased public engagement with science and technology...

  1. Quality assurance program for environmental assessment of Savannah River Plant waste sites: Environmental information document

    International Nuclear Information System (INIS)

    Looney, B.B.; King, C.M.; Stephenson, D.E.

    1987-03-01

    Forty-eight locations were identified that received a variety of radioactive and nonradioactive constituents during the past 35 years including surface impoundments and shallow land burial facilities. Detailed environmental assessments of existing waste disposal areas, as well as new waste disposal techniques and disposition of tritiated water, were completed to air in an evaluation of the low level, mixed and hazardous waste management activities. These assessments result in estimation of risk, or residual risk, posed by each disposal area to various receptors as a function of waste management alternative. For example, at existing waste sites, the closure actions evaluated were waste removal and closure, no waste removal and closure, and no action; several pathways/receptors were considered, including groundwater to river, groundwater to well, atmospheric transport, occupational exposure, direct exposure, and contamination followed by ingestion of crops and meat. Modeling of chemical transport in a variety of media was an integral part of the assessment process. The quality of the models used and the application of these models were assured by an explicit quality assurance program

  2. Information Management Systems for Cultural Heritage and Conservation of World Heritage Sites. The Silk Roads Case Study

    Directory of Open Access Journals (Sweden)

    Ona Vileikis

    2011-12-01

    Full Text Available This paper discusses the application of Information Management Systems (IMS in cultural heritage. IMS offer a set of tools for understanding, inventorying and documenting national, regional and World Heritage properties.  Information Management Systems can assist State Parties, stakeholders and heritage site managers involved in cultural heritage management and conservation by easily mining, sharing and exchanging information from multiple sources based on international standards. Moreover, they aim to record, manage, visualize, analyze and disseminate heritage information. In close collaboration with five Central Asian countries, namely, Turkmenistan, Kazakhstan, Kyrgyzstan, Uzbekistan and Tajikistan; a Belgian consortium headed by the Raymond Lemaire International Centre for Conservation (RLICC, K.U.Leuven is developing the Silk Roads Cultural Heritage Resource Information System (CHRIS. This Web-based Information Management System supports the preparation of the Central Asia Silk Roads serial and transnational nominations on the UNESCO World Heritage list. The project has been set up thanks to the financial support of the Belgian Federal Science Policy Office (BELSPO and in collaboration with UNESCO World Heritage Centre in conjunction with the People’s Republic of China and the Japanese Funds-in-Trust UNESCO project. It provides a holistic approach for the recording, documenta tion, protection and monitoring tasks as part of the management of these potential World Heritage Properties. The Silk Roads CHRIS is easily accessible to the general user, presented in a bilingual English and Russian frame and interoperable, i.e. open for other applications to connect to. In this way, all information for the nomination dossiers is easily verified regarding consistency and quality and ready for managing, periodic reporting and monitoring processes in the respect to the property listed. Fina lly, this study provides a general framework to establish

  3. Ecological site-based assessments of wind and water erosion: informing accelerated soil erosion management in rangelands

    Science.gov (United States)

    Webb, Nicholas P.; Herrick, Jeffrey E.; Duniway, Michael C.

    2014-01-01

    Accelerated soil erosion occurs when anthropogenic processes modify soil, vegetation or climatic conditions causing erosion rates at a location to exceed their natural variability. Identifying where and when accelerated erosion occurs is a critical first step toward its effective management. Here we explore how erosion assessments structured in the context of ecological sites (a land classification based on soils, landscape setting and ecological potential) and their vegetation states (plant assemblages that may change due to management) can inform systems for reducing accelerated soil erosion in rangelands. We evaluated aeolian horizontal sediment flux and fluvial sediment erosion rates for five ecological sites in southern New Mexico, USA, using monitoring data and rangeland-specific wind and water erosion models. Across the ecological sites, plots in shrub-encroached and shrub-dominated vegetation states were consistently susceptible to aeolian sediment flux and fluvial sediment erosion. Both processes were found to be highly variable for grassland and grass-succulent states across the ecological sites at the plot scale (0.25 Ha). We identify vegetation thresholds that define cover levels below which rapid (exponential) increases in aeolian sediment flux and fluvial sediment erosion occur across the ecological sites and vegetation states. Aeolian sediment flux and fluvial erosion in the study area can be effectively controlled when bare ground cover is 100 cm in length is less than ~35%. Land use and management activities that alter cover levels such that they cross thresholds, and/or drive vegetation state changes, may increase the susceptibility of areas to erosion. Land use impacts that are constrained within the range of natural variability should not result in accelerated soil erosion. Evaluating land condition against the erosion thresholds identified here will enable identification of areas susceptible to accelerated soil erosion and the development of

  4. Monitoring of In-Field Variability for Site Specific Crop Management Through Open Geospatial Information

    Science.gov (United States)

    Řezník, T.; Lukas, V.; Charvát, K.; Charvát, K., Jr.; Horáková, Š.; Křivánek, Z.; Herman, L.

    2016-06-01

    The agricultural sector is in a unique position due to its strategic importance around the world. It is crucial for both citizens (consumers) and the economy (both regional and global), which, ideally, should ensure that the whole sector is a network of interacting organisations. It is important to develop new tools, management methods, and applications to improve the management and logistic operations of agricultural producers (farms) and agricultural service providers. From a geospatial perspective, this involves identifying cost optimization pathways, reducing transport, reducing environmental loads, and improving the energy balance, while maintaining production levels, etc. This paper describes the benefits of, and open issues arising from, the development of the Open Farm Management Information System. Emphasis is placed on descriptions of available remote sensing and other geospatial data, and their harmonization, processing, and presentation to users. At the same time, the FOODIE platform also offers a novel approach of yield potential estimations. Validation for one farm demonstrated 70% successful rate when comparing yield results at a farm counting 1'284 hectares on one hand and results of a theoretical model of yield potential on the other hand. The presented Open Farm Management Information System has already been successfully registered under Phase 8 of the Global Earth Observation System of Systems (GEOSS) Architecture Implementation Pilot in order to support the wide variety of demands that are primarily aimed at agriculture and water pollution monitoring by means of remote sensing.

  5. Requirements on information of the site of the European Union from member states within the area of the environment

    International Nuclear Information System (INIS)

    Virgovic, R.; Grofova, R; Sochorova, O.

    2005-01-01

    In this presentation authors deal with requirements on information of the site of the European Union from member states within the area of the environment. As of May 1, 2004 with entrance into the European Union for the Slovak Republic results the responsibility feeding reports about the environment. Reports about the environment (State of the environment Report - Slovak Republic) deal with the following areas: (A) Horizontally measures; (B) Air protection; (C) Waste management; (D) Water protection; (E) Nature protection; (F) Inspection of industrial pollution and risk management; (G) Chemical agents and genetically modified organisms; (H) Noise from motor-cars and machines; (I) Nuclear safety; (J) Civil protection

  6. Convergence Insufficiency, Accommodative Insufficiency, Visual Symptoms, and Astigmatism in Tohono O'odham Students.

    Science.gov (United States)

    Davis, Amy L; Harvey, Erin M; Twelker, J Daniel; Miller, Joseph M; Leonard-Green, Tina; Campus, Irene

    2016-01-01

    Purpose. To determine rate of convergence insufficiency (CI) and accommodative insufficiency (AI) and assess the relation between CI, AI, visual symptoms, and astigmatism in school-age children. Methods. 3rd-8th-grade students completed the Convergence Insufficiency Symptom Survey (CISS) and binocular vision testing with correction if prescribed. Students were categorized by astigmatism magnitude (no/low: <1.00 D, moderate: 1.00 D to <3.00 D, and high: ≥3.00 D), presence/absence of clinical signs of CI and AI, and presence of symptoms. Analyses determine rate of clinical CI and AI and symptomatic CI and AI and assessed the relation between CI, AI, visual symptoms, and astigmatism. Results. In the sample of 484 students (11.67 ± 1.81 years of age), rate of symptomatic CI was 6.2% and symptomatic AI 18.2%. AI was more common in students with CI than without CI. Students with AI only (p = 0.02) and with CI and AI (p = 0.001) had higher symptom scores than students with neither CI nor AI. Moderate and high astigmats were not at increased risk for CI or AI. Conclusions. With-the-rule astigmats are not at increased risk for CI or AI. High comorbidity rates of CI and AI and higher symptoms scores with AI suggest that research is needed to determine symptomatology specific to CI.

  7. Value of information analysis for Corrective Action Unit 97: Yucca Flat, Nevada Test Site, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    IT Corporation Las Vegas

    1999-11-19

    The value-of-information analysis evaluated data collection options for characterizing groundwater transport of contamination associated with the Yucca Flat and Climax Mine Corrective Action Units. Experts provided inputs for the evaluation of 48 characterization options, which included 27 component activities, 12 combinations of activities (subgroups), and 9 combinations of subgroups (groups). The options range from an individual study using existing data and intended to address a relatively narrow uncertainty to a 52-million dollar group of activities designed to collect and analyze new information to broadly address multiple uncertainties. A modified version of the contaminant transport component of the regional model was used to simulate contaminant transport and to estimate the maximum extent of the contaminant boundary, defined as that distance beyond which the committed effective dose equivalent from the residual radionuclides in groundwater will not exceed 4 millirem per year within 1,000 years. These simulations identified the model parameters most responsible for uncertainty over the contaminant boundary and determined weights indicating the relative importance of these parameters. Key inputs were identified through sensitivity analysis; the five selected parameters were flux for flow into Yucca Flat from the north, hydrologic source term, effective porosity and diffusion parameter for the Lower Carbonate Aquifer, and path length from the Volcanic Confining Unit to the Lower Carbonate Aquifer. Four measures were used to quantify uncertainty reduction. Using Bayesian analysis, the options were compared and ranked based on their costs and estimates of their effectiveness at reducing the key uncertainties relevant to predicting the maximum contaminant boundary.

  8. Value of information analysis for Corrective Action Unit 97: Yucca Flat, Nevada Test Site, Nevada

    International Nuclear Information System (INIS)

    1999-01-01

    The value-of-information analysis evaluated data collection options for characterizing groundwater transport of contamination associated with the Yucca Flat and Climax Mine Corrective Action Units. Experts provided inputs for the evaluation of 48 characterization options, which included 27 component activities, 12 combinations of activities (subgroups), and 9 combinations of subgroups (groups). The options range from an individual study using existing data and intended to address a relatively narrow uncertainty to a 52-million dollar group of activities designed to collect and analyze new information to broadly address multiple uncertainties. A modified version of the contaminant transport component of the regional model was used to simulate contaminant transport and to estimate the maximum extent of the contaminant boundary, defined as that distance beyond which the committed effective dose equivalent from the residual radionuclides in groundwater will not exceed 4 millirem per year within 1,000 years. These simulations identified the model parameters most responsible for uncertainty over the contaminant boundary and determined weights indicating the relative importance of these parameters. Key inputs were identified through sensitivity analysis; the five selected parameters were flux for flow into Yucca Flat from the north, hydrologic source term, effective porosity and diffusion parameter for the Lower Carbonate Aquifer, and path length from the Volcanic Confining Unit to the Lower Carbonate Aquifer. Four measures were used to quantify uncertainty reduction. Using Bayesian analysis, the options were compared and ranked based on their costs and estimates of their effectiveness at reducing the key uncertainties relevant to predicting the maximum contaminant boundary

  9. A doppler-based evaluation of peripheral lower limb arterial insufficiency in diabetes mellitus

    International Nuclear Information System (INIS)

    Shaheen, R.; Sohail, S.

    2010-01-01

    To determine the frequency, level and flow patterns of lower limb arterial insufficiency in diabetic patients on Doppler ultrasound study. Study Design: Cross-sectional study. Place and Duration of Study: Radiology Department, Civil Hospital, Karachi, from February 2007 to September 2008. Methodology: One hundred adult diabetic patients with suspected peripheral vascular insufficiency irrespective of gender were included. Demographic data, presenting complaints, treatment history, and level of HbA1c were recorded. Doppler evaluated arterial status and ankle brachial index (ABI) were recorded on proforma. Statistical analysis were done on SPSS version 12. Results: The mean HbA1c was 8.4 +- 1.4 gm/dl, a majority of 77% having a controlled level of < 10 mg/dl. Arterial insufficiency on Doppler ultrasound was documented in 62% (p=0.016) and the dorsalis paedis artery was the predominant site of stenosis (24%). Spectral broadening and biphasic flow were salient features. The mean value of resistive index in stenotic cases was 0.563 +- 0.16 with a mean velocity difference of 0.37 +- 0.29 m/s (p < 0.001) at the site of stenosis. Conclusion: Peripheral vascular insufficiency was a significant finding in patients having diabetes for an average of 9.8 years, even in the presence of controlled HbA1c. The dorsalis paedis was the commonest site of involvement. The insufficiency was moderate with a biphasic flow pattern in a majority of cases. Difference in resistive index and flow velocities at and above the site of stenosis provided an important clue to the diagnosis of level of stenosis that helps in planning limb salvage management. (author)

  10. Energy Facility Siting by Means of Environmental Modelling with LANDSAT, Thematic Mapper and Geographic Information System (GIS) Data

    Science.gov (United States)

    1982-01-01

    Currently based on ground and aerial surveys, the land cover data base of the Pennsylvania Power and Light Company is routinely used for modelling the effects of alternative generating plant and transmission line sites on the local and regional environment. The development of a satellite-based geographic information system would facilitate both the preparation of environmental impact statements by power companies and assessment of the data by the Nuclear Regulatory Commission. A cooperative project is planned to demonstrate the methodology for integrating satellite data into an existing geographic information system, d to further evaluate the ability of satellite data in modeling environmental conditions that would be applied in the preparation and assessment of environmental impact statements.

  11. The controversy on chronic cerebrospinal venous insufficiency

    Directory of Open Access Journals (Sweden)

    Paolo Zamboni

    2013-08-01

    Full Text Available The objective of this review is to analyze the actual scientific controversy on chronic cerebrospinal venous insufficiency (CCSVI and its association with both neurodegenerative disorders and multiple sclerosis (MS. We revised all published studies on prevalence of CCSVI in MS patients, including ultrasound and catheter venography series. Furthermore, we take into consideration other publications dealing with the pathophysiologic consequences of CCSVI in the brain, as well as ecent data characterizing the pathology of the venous wall in course of CCSVI. Finally, safety and pilot data on effectiveness of endovascular CCSVI treatment were further updated. Studies of prevalence show a big variability in prevalence of CCSVI in MS patients assessed by established ultrasonographic criteria. This could be related to high operator dependency of ultrasound. However, 12 studies, by the means of more objective catheter venography, show a prevalence >90% of CCSVI in MS. Global hypo-hypoperfusion of the brain, and reduced cerebral spinal fluid dynamics in MS was shown to be related to CCSVI. Postmortem studies and histology corroborate the 2009 International Union of Phlebology (UIP Consensus decision to insert CCSVI among venous malformations. Finally, safety of balloon angioplasty of the extracranial veins was certainly demonstrated, while prospective data on the potential effectiveness of endovascular treatment of CCSVI support to increase the level of evidence by proceeding with a randomized control trial (RCT. Taking into account the current epidemiological data, including studies on catheter venography, the autoptic findings, and the relationship between CCSVI and both hypo-perfusion and cerebro-spinal fluid flow, we conclude that CCSVI can be definitively inserted among the medical entities. Research is still inconclusive in elucidating the CCSVI role in the pathogenesis of neurological disorders. The controversy between the vascular and the

  12. Tricuspid insufficiency after laser lead extraction.

    Science.gov (United States)

    Rodriguez, Yasser; Mesa, Julian; Arguelles, Eric; Carrillo, Roger G

    2013-08-01

    The use of laser lead extraction (LLE) to remove pacemaker and implantable cardiac defibrillator leads has become more prevalent in the past decade. Though the procedure is associated with a low rate of complications, LLE still poses some risks to patients. Some reports have suggested an increase in tricuspid insufficiency (TI) associated with LLE. We present a series of patients who underwent both LLE and complete evaluation for TI with echocardiographic techniques. From August 2008 to January 2010, 173 prospective, consecutive patients underwent LLE in a single center. All patients had transesophageal echocardiograms (TEE) during the extraction. Fifty-three patients had tricuspid valve function evaluated a day before the procedure with a transthoracic echocardiogram (TTE), during the procedure with a TEE and 2 days postoperatively with a TTE. All 173 patients experienced no change in tricuspid valve function during the procedure with TEE. Of the 53 patients who underwent a complete TI evaluation, 38 were males (72%) and 15 females (38%), with a mean age of 69.45 ± 14.08. Mean ejection fraction was 35.82 ± 14.72. Three (6%) patients experienced TI after the procedure (two mild and one severe, all with tricuspid valve endocarditis); 16 (30%) patients were found to have TI before LLE that returned to normal valve function during or after the procedure. Thirty-four (64%) patients did not experience any significant change of the tricuspid valve performance after LLE. LLE was not associated with increased TI. ©2013, The Authors. Journal compilation ©2013 Wiley Periodicals, Inc.

  13. Progress in evaluation of radionuclide geochemical information developed by DOE high-level nuclear waste repository site projects

    International Nuclear Information System (INIS)

    Meyer, R.E.; Arnold, W.D.; O'Kelley, G.D.; Case, F.I.; Land, J.F.

    1989-08-01

    Information that is being developed by projects within the Department of Energy (DOE) pertinent to the potential geochemical behavior of radionuclides at candidate sites for a high-level radioactive waste repository is being evaluated by Oak Ridge National Laboratory (ORNL) for the Nuclear Regulatory Commission (NRC). During this report period, all experiments were conducted with tuff from the proposed high-level nuclear waste site at Yucca Mountain, Nevada. The principal emphasis in this report period was on column studies of migration of uranium and technetium in water from well J-13 at the Yucca Mountain site. Columns 1 cm in diameter and about 5 cm long were constructed and carefully packed with ground tuff. The characteristics of the columns were tested by determination of elution curves of tritium and TcO 4 - . Elution peaks obtained in past studies with uranium were asymmetrical and the shapes were often complex, observations that suggested irreversibilities in the sorption reaction. To try to understand these observations, the effects of flow rate and temperature on uranium migration were studied in detail. Sorption ratios calculated from the elution peaks became larger as the flow rate decreased and as the temperature increased. These observations support the conclusion that the sorption of uranium is kinetically hindered. To confirm this, batch sorption ratio experiments were completed for uranium as a function of time for a variety of conditions

  14. Examining Users' E-Satisfaction in the Usage of Social Networking Sites; Contribution from Utilitarian and Hedonic Information Systems

    Science.gov (United States)

    Ariff, Mohd Shoki Md; Shan, Tay Kai; Zakuan, Norhayati; Ishak, Nawawi; Ridzuan Wahi, Mohd

    2014-06-01

    E-satisfaction (eSAT) is an important success factor of online service providers such as social networking sites (SNSs). The utilitarian and hedonic information systems are crucial in determining users' eSAT of SNSs, especially among young users. The utilitarian aspect of an information system is productivity-oriented which aims to enhance the users' task performance, and it is important in measuring eSAT of SNSs. In this study, the original constructs of Perceived Ease of Use (PEOU) and Perceived Usefulness (PU) of TAM of utilitarian information system was first developed in this research framework. The use of SNSs, such as Facebook, is pleasure-oriented, in which self-fulfilling values to the users are important in determining users' satisfaction towards the SNSs. Therefore, Perceived Enjoyment (PE) of hedonic information system is added to the framework. Thus, the research framework of this study includes both utilitarian (PEOU and PU) and hedonic (PE) aspects of information systems to determine Malaysian young users' eSAT in the usage of Facebook, a social networking site. In this framework, the effects of PEOU, PU and PE on eSAT in the usage of Facebook are examined among Facebook's users in the age of 18 - 24 years old. The effects of PEOU on PU and PE are also examined. Online questionnaire survey was employed and a total of 384 sets of questionnaires were gathered from users of Facebook. The results indicated that PEOU has positive effects on PU and PE in the context of Facebook. In addition, PEOU, PU and PE are also found to have positive effects on eSAT. PE of hedonic information system exerted higher effect on eSAT, compared to PEOU and PU of utilitarian information system, highlighting the importance of pleasure orientation in the usage of Facebook of SNSs. Managerial and theoretical implications of the study are discussed in term of measuring and enhancing users' eSAT in the usage of SNSs, particularly Facebook.

  15. DNA Compass: a secure, client-side site for navigating personal genetic information.

    Science.gov (United States)

    Curnin, Charles; Gordon, Assaf; Erlich, Yaniv

    2017-07-15

    Millions of individuals have access to raw genomic data using direct-to-consumer companies. The advent of large-scale sequencing projects, such as the Precision Medicine Initiative, will further increase the number of individuals with access to their own genomic information. However, querying genomic data requires a computer terminal and computational skill to analyze the data-an impediment for the general public. DNA Compass is a website designed to empower the public by enabling simple navigation of personal genomic data. Users can query the status of their genomic variants for over 1658 markers or tens of millions of documented single nucleotide polymorphisms (SNPs). DNA Compass presents the relevant genotypes of the user side-by-side with explanatory scientific resources. The genotype data never leaves the user's computer, a feature that provides improved security and performance. More than 12 000 unique users, mainly from the general genetic genealogy community, have already used DNA Compass, demonstrating its utility. DNA Compass is freely available on https://compass.dna.land . yaniv@cs.columbia.edu. © The Author(s) 2017. Published by Oxford University Press.

  16. Information on Hydrologic Conceptual Models, Parameters, Uncertainty Analysis, and Data Sources for Dose Assessments at Decommissioning Sites

    International Nuclear Information System (INIS)

    Meyer, Philip D.; Gee, Glendon W.; Nicholson, Thomas J.

    1999-01-01

    This report addresses issues related to the analysis of uncertainty in dose assessments conducted as part of decommissioning analyses. The analysis is limited to the hydrologic aspects of the exposure pathway involving infiltration of water at the ground surface, leaching of contaminants, and transport of contaminants through the groundwater to a point of exposure. The basic conceptual models and mathematical implementations of three dose assessment codes are outlined along with the site-specific conditions under which the codes may provide inaccurate, potentially nonconservative results. In addition, the hydrologic parameters of the codes are identified and compared. A methodology for parameter uncertainty assessment is outlined that considers the potential data limitations and modeling needs of decommissioning analyses. This methodology uses generic parameter distributions based on national or regional databases, sensitivity analysis, probabilistic modeling, and Bayesian updating to incorporate site-specific information. Data sources for best-estimate parameter values and parameter uncertainty information are also reviewed. A follow-on report will illustrate the uncertainty assessment methodology using decommissioning test cases

  17. Information on Hydrologic Conceptual Models, Parameters, Uncertainty Analysis, and Data Sources for Dose Assessments at Decommissioning Sites

    International Nuclear Information System (INIS)

    Meyer D, Philip; Gee W, Glendon

    2000-01-01

    This report addresses issues related to the analysis of uncertainty in dose assessments conducted as part of decommissioning analyses. The analysis is limited to the hydrologic aspects of the exposure pathway involving infiltration of water at the ground surface, leaching of contaminants, and transport of contaminants through the groundwater to a point of exposure. The basic conceptual models and mathematical implementations of three dose assessment codes are outlined along with the site-specific conditions under which the codes may provide inaccurate, potentially nonconservative results. In addition, the hydrologic parameters of the codes are identified and compared. A methodology for parameter uncertainty assessment is outlined that considers the potential data limitations and modeling needs of decommissioning analyses. This methodology uses generic parameter distributions based on national or regional databases, sensitivity analysis, probabilistic modeling, and Bayesian updating to incorporate site-specific information. Data sources for best-estimate parameter values and parameter uncertainty information are also reviewed. A follow-on report will illustrate the uncertainty assessment methodology using decommissioning test cases

  18. Patterns and effects of GC3 heterogeneity and parsimony informative sites on the phylogenetic tree of genes.

    Science.gov (United States)

    Ma, Shuai; Wu, Qi; Hu, Yibo; Wei, Fuwen

    2018-05-20

    The explosive growth in genomic data has provided novel insights into the conflicting signals hidden in phylogenetic trees. Although some studies have explored the effects of the GC content and parsimony informative sites (PIS) on the phylogenetic tree, the effect of the heterogeneity of the GC content at the first/second/third codon position on parsimony informative sites (GC1/2/3 PIS ) among different species and the effect of PIS on phylogenetic tree construction remain largely unexplored. Here, we used two different mammal genomic datasets to explore the patterns of GC1/2/3 PIS heterogeneity and the effect of PIS on the phylogenetic tree of genes: (i) all GC1/2/3 PIS have obvious heterogeneity between different mammals, and the levels of heterogeneity are GC3 PIS  > GC2 PIS  > GC1 PIS ; (ii) the number of PIS is positively correlated with the metrics of "good" gene tree topologies, and excluding the third codon position (C3) decreases the quality of gene trees by removing too many PIS. These results provide novel insights into the heterogeneity pattern of GC1/2/3 PIS in mammals and the relationship between GC3/PIS and gene trees. Additionally, it is necessary to carefully consider whether to exclude C3 to improve the quality of gene trees, especially in the super-tree method. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. Networks of high mutual information define the structural proximity of catalytic sites: implications for catalytic residue identification.

    Directory of Open Access Journals (Sweden)

    Cristina Marino Buslje

    Full Text Available Identification of catalytic residues (CR is essential for the characterization of enzyme function. CR are, in general, conserved and located in the functional site of a protein in order to attain their function. However, many non-catalytic residues are highly conserved and not all CR are conserved throughout a given protein family making identification of CR a challenging task. Here, we put forward the hypothesis that CR carry a particular signature defined by networks of close proximity residues with high mutual information (MI, and that this signature can be applied to distinguish functional from other non-functional conserved residues. Using a data set of 434 Pfam families included in the catalytic site atlas (CSA database, we tested this hypothesis and demonstrated that MI can complement amino acid conservation scores to detect CR. The Kullback-Leibler (KL conservation measurement was shown to significantly outperform both the Shannon entropy and maximal frequency measurements. Residues in the proximity of catalytic sites were shown to be rich in shared MI. A structural proximity MI average score (termed pMI was demonstrated to be a strong predictor for CR, thus confirming the proposed hypothesis. A structural proximity conservation average score (termed pC was also calculated and demonstrated to carry distinct information from pMI. A catalytic likeliness score (Cls, combining the KL, pC and pMI measures, was shown to lead to significantly improved prediction accuracy. At a specificity of 0.90, the Cls method was found to have a sensitivity of 0.816. In summary, we demonstrate that networks of residues with high MI provide a distinct signature on CR and propose that such a signature should be present in other classes of functional residues where the requirement to maintain a particular function places limitations on the diversification of the structural environment along the course of evolution.

  20. Networks of high mutual information define the structural proximity of catalytic sites: implications for catalytic residue identification.

    Science.gov (United States)

    Marino Buslje, Cristina; Teppa, Elin; Di Doménico, Tomas; Delfino, José María; Nielsen, Morten

    2010-11-04

    Identification of catalytic residues (CR) is essential for the characterization of enzyme function. CR are, in general, conserved and located in the functional site of a protein in order to attain their function. However, many non-catalytic residues are highly conserved and not all CR are conserved throughout a given protein family making identification of CR a challenging task. Here, we put forward the hypothesis that CR carry a particular signature defined by networks of close proximity residues with high mutual information (MI), and that this signature can be applied to distinguish functional from other non-functional conserved residues. Using a data set of 434 Pfam families included in the catalytic site atlas (CSA) database, we tested this hypothesis and demonstrated that MI can complement amino acid conservation scores to detect CR. The Kullback-Leibler (KL) conservation measurement was shown to significantly outperform both the Shannon entropy and maximal frequency measurements. Residues in the proximity of catalytic sites were shown to be rich in shared MI. A structural proximity MI average score (termed pMI) was demonstrated to be a strong predictor for CR, thus confirming the proposed hypothesis. A structural proximity conservation average score (termed pC) was also calculated and demonstrated to carry distinct information from pMI. A catalytic likeliness score (Cls), combining the KL, pC and pMI measures, was shown to lead to significantly improved prediction accuracy. At a specificity of 0.90, the Cls method was found to have a sensitivity of 0.816. In summary, we demonstrate that networks of residues with high MI provide a distinct signature on CR and propose that such a signature should be present in other classes of functional residues where the requirement to maintain a particular function places limitations on the diversification of the structural environment along the course of evolution.

  1. The Use Of Information And Communication Technology And Social Networking Sites In Political Governance Of East African Legislative Assembly Parliament

    Directory of Open Access Journals (Sweden)

    Ainebyona Robert

    2015-06-01

    Full Text Available Abstract This research project was carried out to ascertain the use of Information and Communication Technologies and Social Networking Sites in political governance of East African Legislative Assembly Parliament. The research project was based on the conviction that in this era of globalization use of ICTs and SNSs are fundamentally important and will have tremendous impact on governance leadership and legislation now and in the near future. The specific objective of this study was intended a To evaluate the use of Social Networking Sites in enhancing the political governance of East African Legislative assembly Parliament. The findings from the research showed that that all the respondents 100 were subscribed to social networking sites and used them from time to time. Additionally the EALA parliamentarians had a disparity when it came to use of SNSs to interact with constituents 73.3 of the respondents indicated that they have used SNSs to interact with constituents on matters affecting the community from time to time however 26.7 showed that they did not use Social Networking sites to interact with constituents. Lastly the use of ICTs and SNSs by EALA has also made it possible for citizens to view Assembly proceedings in real time and hence where able to view their representatives in the course of carrying out their duties in the political arena.Lastly the world is changing in a dynamic fashion SNSs are among the tools leading the transformation and it is about time Parliamentarians in Africa embrace SNSs as major tools in changing how leaders interact and remain accountable to their constituents a practice thats been a myth in Africa.

  2. Renal tubular acidosis complicated with hyponatremia due to cortisol insufficiency

    OpenAIRE

    Izumi, Yuichiro; Nakayama, Yushi; Onoue, Tomoaki; Inoue, Hideki; Mukoyama, Masashi

    2015-01-01

    Adrenocortical insufficiency such as occurs in Addison's disease causes hyponatremia and renal tubular acidosis (RTA). Hyponatremia results from both aldosterone and cortisol insufficiency. RTA is due to aldosterone insufficiency. The involvement of cortisol in RTA is unclear. Here, we report a woman in her 70s who was admitted to our hospital with severe hyponatremia (106 mEq/l) and RTA. The patient exhibited low plasma cortisol levels with little response to rapid adrenocorticotropic hormon...

  3. Efficient use of information in adaptive management with an application to managing recreation near golden eagle nesting sites.

    Directory of Open Access Journals (Sweden)

    Paul L Fackler

    Full Text Available It is generally the case that a significant degree of uncertainty exists concerning the behavior of ecological systems. Adaptive management has been developed to address such structural uncertainty, while recognizing that decisions must be made without full knowledge of how a system behaves. This paradigm attempts to use new information that develops during the course of management to learn how the system works. To date, however, adaptive management has used a very limited information set to characterize the learning that is possible. This paper uses an extension of the Partial Observable Markov Decision Process (POMDP framework to expand the information set used to update belief in competing models. This feature can potentially increase the speed of learning through adaptive management, and lead to better management in the future. We apply this framework to a case study wherein interest lies in managing recreational restrictions around golden eagle (Aquila chrysaetos nesting sites. The ultimate management objective is to maintain an abundant eagle population in Denali National Park while minimizing the regulatory burden on park visitors. In order to capture this objective, we developed a utility function that trades off expected breeding success with hiker access. Our work is relevant to the management of human activities in protected areas, but more generally demonstrates some of the benefits of POMDP in the context of adaptive management.

  4. Security Notice To Federal, State and Local Officials Receiving Access to the Risk Management Program’s Off-site Consequence Analysis Information

    Science.gov (United States)

    Based on the Chemical Safety Information, Site Security and Fuels Regulatory Relief Act (CSISSFRRA), this notice states that while you may share with the public data from OCA sections, it is illegal to disclose/distribute the sections themselves.

  5. Prevalence and Predictors of Functional Vitamin K Insufficiency in Mothers and Newborns in Uganda

    Directory of Open Access Journals (Sweden)

    Data Santorino

    2015-10-01

    Full Text Available Vitamin K deficiency bleeding (VKDB in infancy is a serious but preventable cause of mortality or permanent disability. Lack of epidemiologic data for VKDB in sub-Saharan Africa hinders development and implementation of effective prevention strategies. We used convenience sampling to consecutively enroll mothers delivering in a southwestern Uganda Hospital. We collected socio-demographic and dietary information, and paired samples of maternal venous and neonatal cord blood for the immunoassay of undercarboxylated prothrombin (PIVKA-II, a sensitive marker of functional vitamin K (VK insufficiency. We used univariable and multivariable logistic regression models to identify predictors of VK insufficiency. We detected PIVKA-II of ≥0.2 AU (Arbitrary Units per mL/mL (indicative of VK insufficiency in 33.3% (47/141 of mothers and 66% (93/141 of newborns. Importantly, 22% of babies had PIVKA-II concentrations ≥5.0 AU/mL, likely to be associated with abnormal coagulation indices. We found no significant predictors of newborn VK insufficiency, including infant weight (AOR (adjusted odds ratio 1.85, 95% CI (confidence interval 0.15–22.49, gender (AOR 0.54, 95% CI 0.26–1.11, term birth (AOR 0.72, 95% CI 0.20–2.62, maternal VK-rich diet (AOR 1.13, 95% CI 0.55–2.35 or maternal VK insufficiency (AOR 0.99, 95% CI 0.47–2.10. VK insufficiency is common among mothers and newborn babies in southwestern Uganda, which in one fifth of babies nears overt deficiency. Lack of identifiable predictors of newborn VK insufficiency support strategies for universal VK prophylaxis to newborns to prevent VKDB.

  6. Vertebrobasilar insufficiency and possible relationships with arterial changes

    International Nuclear Information System (INIS)

    Tonagel, J.

    1982-01-01

    The study described was carried out in order to clarify the question as to whether overt neurological disorders in the vertebrobasilar region are connected with arterial changes that may be ascertained by means of X-ray examinations. For this purpose, the clinical and angiographic data of 54 patients showing vertebrobasilar insufficiency were subjected to detailed analysis. In all cases, an angiographic examination of the branchial artery had been so performed as to permit visualisation of the vertebrobasilar territory. The macroscopic changes revealed by angiography were evaluated on the basis of the severity of the clinical symptoms and the age of the patient. It was found that the frequency of visualised changes in the arterial system that could be matched with neurological symptoms only just attained statistical significance in women of advanced age, while the findings revealed in men were not consistent with the clinical signs. The manifestation of those changes largely depends on the individual degree of collateral blood supply. This, a direct relationship between the angiographic findings and the clinical symptoms is only likely to be observed in cases where the development of collaterals was prevented due to the site of vascular obstruction or where the incident happened just prior to the examination. A typical example here is recent thrombosis of the basilar artery. (TRV) [de

  7. Potential Role of Land Use and Land Cover Information in Powerplant Siting: Example of Three Mile Island

    Science.gov (United States)

    Wray, J. R.

    1982-01-01

    Selecting a site for a nuclear powerplant can be helped by digitizing land use and land cover data, population data, and other pertinent data sets, and then placing them in a geographic information system. Such a system begins with a set of standardized maps for location reference and then provides for retrieval and analysis of spatial data keyed to the maps. This makes possible thematic mapping by computer, or interactive visual display for decisionmaking. It also permits correlating land use area measurements with census and other data (such as fallout dosages), and the updating of all data sets. The system is thus a tool for dealing with resource management problems and for analyzing the interaction between people and their environment. An explanation of a computer-plotted map of land use and cover for Three Mile Island and vicinity is given.

  8. An informal judgment assessment of subsidence mitigation options for low-level radioactive waste management on the Nevada Test Site

    International Nuclear Information System (INIS)

    Crowe, B.M.; Besinger, H.; Dolenc, M.

    1999-01-01

    An assessment of options to mitigate the effects of subsidence at low-level radioactive waste disposal sites on the Nevada Test Site was conducted using an informal method of expert judgment. Mitigation options for existing waste cells and future waste cells were identified by a committee composed of knowledgeable personnel from the DOE and DOE-contractors. Eight ranking factors were developed to assess the mitigation options and these factors were scored through elicitation of consensus views from the committee. Different subsets of the factors were applied respectively, to existing waste cells and future waste cells, and the resulting scores were ranked using weighted and unweighted scores. These scores show that there is a large number of viable mitigation options and considerable flexibility in assessing the subsidence issue with a greater range of options for future waste cells compared to existing waste cells. A highly ranked option for both existing and future waste cells is covering the waste cells with a thick closure cap of native alluvium

  9. Informational value and bias of videos related to orthodontics screened on a video-sharing Web site.

    Science.gov (United States)

    Knösel, Michael; Jung, Klaus

    2011-05-01

    To assess the informational value, intention, source, and bias of videos related to orthodontics screened by the video-sharing Internet platform YouTube. YouTube (www.youtube.com) was scanned in July 2010 for orthodontics-related videos using an adequately defined search term. Each of the first 30 search results of the scan was categorized with the system-generated sorts "by relevance" and "most viewed" (total: 60). These were rated independently by three assessors, who completed a questionnaire for each video. The data were analyzed statistically using Friedman's test for dependent samples, Kendall's tau, and Fleiss's kappa. The YouTube scan produced 5140 results. There was a wide variety of information about orthodontics available on YouTube, and the highest proportion of videos was found to originate from orthodontic patients. These videos were also the most viewed ones. The informational content of most of the videos was generally judged to be low, with a rather poor to inadequate representation of the orthodontic profession, although a moderately pro-orthodontics stance prevailed. It was noticeable that the majority of contributions of orthodontists to YouTube constituted advertising. This tendency was not viewed positively by the majority of YouTube users, as was evident in the divergence in the proportions when sorting by "relevance" and "most viewed." In the light of the very large number of people using the Internet as their primary source of information, orthodontists should recognize the importance of YouTube and similar social media Web sites in the opinion-forming process, especially in the case of adolescents.

  10. FF Site Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes the EPA Federal Agency Hazardous Waste Compliance Docket (Docket), which is required by Section 120(c) of the Comprehensive Environmental...

  11. Accuracy of Self-Reported Breast Cancer Information among Women from the Ontario Site of the Breast Cancer Family Registry

    International Nuclear Information System (INIS)

    Barisic, A.; Glendon, G.; Andrulis, I. L.; Knight, J. A.; Barisic, A.; Knight, J. A.; Glendon, G.; Weerasooriya, N.; Andrulis, I. L.

    2012-01-01

    Obtaining complete medical record information can be challenging and expensive in breast cancer studies. The current literature is limited with respect to the accuracy of self-report and factors that may influence this. We assessed the agreement between self-reported and medical record breast cancer information among women from the Ontario site of the Breast Cancer Family Registry. Women aged 20-69 years diagnosed with incident breast cancer 1996-1998 were identified from the Ontario Cancer Registry, sampled on age and family history. We calculated kappa statistics, proportion correct, sensitivity, specificity, and positive and negative predictive values and conducted unconditional logistic regression to examine whether characteristics of the women influenced agreement. The proportions of women who correctly reported having received a broad category of therapy (hormone therapy, chemotherapy, radiation, or surgery) as well as sensitivity and specificity were above 90%, and the kappa statistics were above 0.80. The specific type of hormonal or chemotherapy was reported with low-to-moderate agreement. Aside from recurrence, no factors were consistently associated with agreement. Thus, most women were able to accurately report broad categories of treatment but not necessarily specific treatment types. The finding of this study can aid researchers in the use and design of self-administered treatment questionnaires

  12. SITE SELECTION OF MUNICIPAL SOLID WASTE LANDFILLS USING ANALYTICAL HIERARCHY PROCESS METHOD IN A GEOGRAPHICAL INFORMATION TECHNOLOGY ENVIRONMENT IN GIROFT

    Directory of Open Access Journals (Sweden)

    H. Javaheri, T. Nasrabadi, M. H. Jafarian, G. R. Rowshan, H. Khoshnam

    2006-07-01

    Full Text Available Municipal solid waste generation is among the most significant sources which threaten the global environmental health. As an ideal selection depends on considering several independent factors concerning land use, socio economy and hydrogeology, the use of a multi criteria evaluation method seems inevitable. Taking benefit of geographic information system as a tool in combination with geographical information technology, equips the spatial decision support systems in appropriate site selection of sanitary landfills. The present study involves a kind of multi criteria evaluation method under the name of weighted linear combination by using geographical information technology as a practical instrument to evaluate the suitability of the vicinity of Giroft city in Kerman province of Iran for landfill. Water permeability, slope, distance from rivers, depth of underground watertable, distance from residential areas, distance from generation centers, general environmental criterion and distance from roads are the criteria which have been taken in to consideration in the process of analyzing. Superposing all of the raster type layers including geomorphologic, hydrologic, humanistic and land use criteria in land suitability, the final zoning of appropriate, fairly appropriate and inappropriate districts have been identified. Considering relative priority of all criteria in comparison with others, a specific weight is designated to each criterion according to their total influence on the whole process of decision making. The results from the application of the presented methodology are zones for landfill with varying zonal land suitability. Finally the zones will be ranked in descending order to indicate the priority of different options in front of the eyes of decision makers. The results achieved by this study may help policy makers of Giroft city by a variety of options for being considered as sanitary landfill locations.

  13. Magnetic resonance imaging in osteomalacic insufficiency fractures of the pelvis

    Energy Technology Data Exchange (ETDEWEB)

    Kanberoglu, K. [Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey)]. E-mail: zkanber@istanbul.edu.tr; Kantarci, F. [Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey); Cebi, D. [Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey); Yilmaz, M.H. [Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey); Kurugoglu, S. [Department of Radiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey); Bilici, A. [Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey); Koyuncu, H. [Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty, Istanbul University, Istanbul (Turkey)

    2005-01-01

    AIMS: To report the magnetic resonance imaging (MRI) findings of osteomalacic insufficiency fractures of the pelvis. MATERIALS AND METHODS: In all, 12 persons presenting with chronic pelvic pain and with a definitive diagnosis of osteomalacia (OM) were enrolled in this study. Radiological work-up included direct radiographs (n=12), computed tomography (n=5), scintigraphy n=12) and MRI (n=12). The location of the insufficiency fractures and corresponding MRI appearances were evaluated. Depending on the presence or absence of signal intensity around the fractures, the lesions were grouped into active and chronic forms. RESULTS: A total of 34 insufficiency fractures were depicted on imaging studies. MRI demonstrated 33 of the lesions. All the insufficiency fractures were seen as a hypointense lines or fissures on T1- and T2-weighted and STIR MR images. There was a high frequency of insufficiency fractures at the sacrum and iliac bone (16/34, 47%). Overall, 11 chronic-type (no abnormal signal intensity around the fissure) and 22 active-type (abnormal signal intensity around the fissure) insufficiency fractures were detected by MRI. Follow-up MR examinations of 2 subjects showed that abnormal signal intensity had disappeared after appropriate treatment. CONCLUSION: The results of this study showed that the iliac and sacral bones are frequently involved in patients with OM. MRI can determine the clinical activity of the disease, and can monitor the response to treatment of the active type of insufficiency fractures.

  14. Magnetic resonance imaging in osteomalacic insufficiency fractures of the pelvis

    International Nuclear Information System (INIS)

    Kanberoglu, K.; Kantarci, F.; Cebi, D.; Yilmaz, M.H.; Kurugoglu, S.; Bilici, A.; Koyuncu, H.

    2005-01-01

    AIMS: To report the magnetic resonance imaging (MRI) findings of osteomalacic insufficiency fractures of the pelvis. MATERIALS AND METHODS: In all, 12 persons presenting with chronic pelvic pain and with a definitive diagnosis of osteomalacia (OM) were enrolled in this study. Radiological work-up included direct radiographs (n=12), computed tomography (n=5), scintigraphy n=12) and MRI (n=12). The location of the insufficiency fractures and corresponding MRI appearances were evaluated. Depending on the presence or absence of signal intensity around the fractures, the lesions were grouped into active and chronic forms. RESULTS: A total of 34 insufficiency fractures were depicted on imaging studies. MRI demonstrated 33 of the lesions. All the insufficiency fractures were seen as a hypointense lines or fissures on T1- and T2-weighted and STIR MR images. There was a high frequency of insufficiency fractures at the sacrum and iliac bone (16/34, 47%). Overall, 11 chronic-type (no abnormal signal intensity around the fissure) and 22 active-type (abnormal signal intensity around the fissure) insufficiency fractures were detected by MRI. Follow-up MR examinations of 2 subjects showed that abnormal signal intensity had disappeared after appropriate treatment. CONCLUSION: The results of this study showed that the iliac and sacral bones are frequently involved in patients with OM. MRI can determine the clinical activity of the disease, and can monitor the response to treatment of the active type of insufficiency fractures

  15. Traveling Exhibitions as Sites for Informal Learning: Assessing Different Strategies with Field Trips to Traveling Exhibitions at Non-Museum Sites

    Science.gov (United States)

    Harker, Richard J. W.; Badger, James

    2015-01-01

    This study investigated the use of different pedagogical techniques to create an intellectually engaging experience for middle school students who visited a traveling exhibition from the United States Holocaust Memorial Museum at a non-museum host site: the University of North Georgia Dahlonega's Library and Technology Center. The findings of this…

  16. Value of information analysis for Corrective Action Unit Nos. 101 and 102: Central and western Pahute Mesa, Nevada Test Site, Nevada

    International Nuclear Information System (INIS)

    1998-09-01

    The purpose of this report is to describe the basis for and present the results of a value of information analysis (VOIA) for the Pahute Mesa underground test area of the Nevada Test Site (NTS), one of several areas of the Nevada Test Site used for underground nuclear testing in the past. The value of information analysis was used to evaluate and compare potential characterization options at the Pahute Mesa underground test area for site remediation purposes. Thirty six characterization options were evaluated, ranging from a single, inexpensive study using existing data and intended to address a single question or uncertainty, to a forty-million-dollar suite of activities designed to collect and analyze new information to address multiple uncertainties. The characterization options were compared and ranked based on how effective the experts though the information collection would be in reducing uncertainties, how this effected the distance to contaminant boundary, and the cost of the option

  17. Optimal site selection for sitting a solar park using multi-criteria decision analysis and geographical information systems

    Science.gov (United States)

    Georgiou, Andreas; Skarlatos, Dimitrios

    2016-07-01

    Among the renewable power sources, solar power is rapidly becoming popular because it is inexhaustible, clean, and dependable. It has also become more efficient since the power conversion efficiency of photovoltaic solar cells has increased. Following these trends, solar power will become more affordable in years to come and considerable investments are to be expected. Despite the size of solar plants, the sitting procedure is a crucial factor for their efficiency and financial viability. Many aspects influence such a decision: legal, environmental, technical, and financial to name a few. This paper describes a general integrated framework to evaluate land suitability for the optimal placement of photovoltaic solar power plants, which is based on a combination of a geographic information system (GIS), remote sensing techniques, and multi-criteria decision-making methods. An application of the proposed framework for the Limassol district in Cyprus is further illustrated. The combination of a GIS and multi-criteria methods produces an excellent analysis tool that creates an extensive database of spatial and non-spatial data, which will be used to simplify problems as well as solve and promote the use of multiple criteria. A set of environmental, economic, social, and technical constrains, based on recent Cypriot legislation, European's Union policies, and expert advice, identifies the potential sites for solar park installation. The pairwise comparison method in the context of the analytic hierarchy process (AHP) is applied to estimate the criteria weights in order to establish their relative importance in site evaluation. In addition, four different methods to combine information layers and check their sensitivity were used. The first considered all the criteria as being equally important and assigned them equal weight, whereas the others grouped the criteria and graded them according to their objective perceived importance. The overall suitability of the study

  18. Use of the Geographic Information System and Analytic Hierarchy Process for Municipal Solid Waste Landfill Site Selection: A Case Study of Najafabad, Iran

    Directory of Open Access Journals (Sweden)

    A. Afzali

    2014-03-01

    Full Text Available Following technological advancements and integrated municipal solid waste management in recent decades, various methods such as recycling, biotreatment, thermal treatment, and sanitary landfills have been developed and employed. Creating sanitary landfills is a major strategy in the integrated solid waste management hierarchy. It is cheaper and thus more common than other disposal methods. Selecting a suitable solid waste landfill site can prevent adverse ecological and socioeconomic effects. Landfill site selection requires the analysis of spatial data, regulations, and accepted criteria. The present study aimed to use the geographic information system and the analytic hierarchy process to identify an appropriate landfill site for municipal solid wastes in Najafabad (Isfahan, Iran. Environmental and socioeconomic criteria were evaluated through different information layers in the Boolean and fuzzy logics. The analytical hierarchy process was applied for weighing the fuzzy information layers. Subsequently, two suitable sites were identified by superimposing the maps from the Boolean and fuzzy logics and considering the minimum required landfill area for 20 years. However, proximity of these two sites to Tiran (a nearby city made them undesirable landfill sites for Najafabad. Therefore, due to the existing restrictions in Najafabad, the possibility of creating landfill sites in common with adjacent cities should be further investigated.

  19. Prevalence and correlates of insufficient physical activity in school adolescents in Peru.

    Science.gov (United States)

    Sharma, Bimala; Chavez, Rosemary Cosme; Nam, Eun Woo

    2018-01-01

    OBJECTIVE To assess the prevalence and correlates of insufficient physical activity in adolescents in Peru. METHODS We used a self-administered questionnaire developed from Global school-based Student Health Survey to collect information from secondary school students in North Lima and Callao in 2015. We carried out Poisson regression with robust variance using generalized linear models to estimate the crude and adjusted prevalence ratios (APR) with 95% confidence intervals (95%CI) of insufficient physical activity for its correlates. RESULTS We have found that 78% of the adolescents did not meet the global recommendation of the World Health Organization on physical activity in the last week before the survey. Female respondents (APR = 1.13, 95%CI 1.04-1.21), respondents who perceived themselves as overweight (APR = 1.10, 95%CI 1.03-1.18), and respondents who consumed insufficient vegetables and fruits [no vegetables (APR = 1.30, 95%CI 1.06-1.59), no fruits (APR = 1.15, 95%CI 1.00-1.31) as compared to those who consumed ≥ 2 servings every day in the last seven days] were more likely to report insufficient physical activity. Adolescents who worked after school (APR = 0.92, 95%CI 0.84-0.99), had physical education classes five times per week (APR = 0.94, 95%CI 0.88-0.99), and had parental supervision (APR = 0.92, 95%CI 0.87-0.98) were less likely to report insufficient physical activity. CONCLUSIONS Sex, work after school, perceived body weight, physical education class, parental support, and healthy dietary behaviors were associated with insufficient physical activity. Attempts to improve physical activity should look for ways to enhance leisure-time physical activity, parental support, physical education classes, healthy dietary behaviors, and normal body weight maintenance in adolescents with integrated efforts from the family and school.

  20. Matching indices taking the dynamic hybrid electrical and thermal grids information into account for the decision-making of nZEB on-site renewable energy systems

    International Nuclear Information System (INIS)

    Cao, Sunliang; Sirén, Kai

    2015-01-01

    Highlights: • Use dynamic hourly-based grid information (PEF/CEF/tariffs) in nZEB control. • Hourly dynamic primary energy factor, CO 2 factor and tariffs for hybrid grids. • Methodology which links the on-site matching with dynamic grid information. • Multi-objective control indicators reflects both matching and grid information. • The influence of the dynamic grid information on the energy/environment/cost. - Abstract: Future nearly-zero energy buildings (nZEBs) will be involved with the twofold problem of on-site matching and hybrid–grid interactions. Theoretically, the hybrid grids’ information is dynamic, such as primary energy factors, equivalent CO 2 emission factors, and grid tariffs. Regarding primary energy consumption, equivalent CO 2 emissions or the grid cost of the nZEB, the significance of specific aspects of the matching capability, such as on-site energy faction (OEF) and on-site energy matching (OEM), will also become dynamic and variable with respect to the evolution of the grid information. Therefore, the primary goal is to develop a methodology as a multi-objective control criterion for the nZEB energy system, which can reflect both the on-site matching capability and dynamic grid information of environmental or economic impacts. The developed methodology is to quantitatively link the dynamic grid information with the weighting factors of the weighted matching index (WMI), following the monotone relationships between the extended matching indices and grid information. The methodology is implemented in this study to control an nZEB energy system with hybrid grid connections. The results show that the developed methodology can seek an optimised balance between the objectives of maximising the matching capability and minimising the environmental/economic load

  1. A geographic information system and multi criteria analysis method for site selection of spent nuclear fuel disposal

    International Nuclear Information System (INIS)

    Martins, Vivian Borges

    2009-01-01

    This thesis aims to develop a site selection methodology for the construction of final repository for the spent nuclear fuel disposal, by using geographic information systems (GIS) and multi-criteria decision analysis. Decision making processes of this kind are often complex, given the great number of space parameters to consider and also the typically conflicting opinions of the diverse stake holders. By using GIS, data from different space parameters can be quickly and reliably stored, treated and analyzed. Multi-criteria techniques allow for the incorporation of different stake holders' opinions. These tools, when jointly used, allow for the decision process to be more transparent, quick and reliable. The method developed was applied to the particular case of the state of Rio de Janeiro. Weights obtained from an expert panel and also by using the Hierarchical Analysis Method and cartographic data were combined in the GIS. The application showed that it is possible not only to select and classify areas as to their aptness for the proposed objective, but also to exclude those clearly inadequate areas, thus optimizing the selection process by reducing the search space and consequently minimizing costs and the time spent in the search. (author)

  2. INEL cold test pit demonstration of improvements in information derived from non-intrusive geophysical methods over buried waste sites

    International Nuclear Information System (INIS)

    1993-01-01

    The objectives of this research project were to lay the foundation for further improvement in the use of geophysical methods for detection of buried wastes, and to increase the information content derived from surveys. Also, an important goal was to move from mere detection to characterization of buried wastes. The technical approach to achieve these objectives consisted of: (1) Collect a data set of high spatial density; (2) Acquire data with multiple sensors and integrate the interpretations inferred from the various sensors; (3) Test a simplified time domain electromagnetic system; and (4) Develop imaging and display formats of geophysical data readily understood by environmental scientists and engineers. The breadth of application of this work is far reaching. Not only are uncontrolled waste pits and trenches, abandoned underground storage tanks, and pipelines found throughout most US DOE facilities, but also at military installations and industrial facilities. Moreover, controlled land disposal sites may contain ''hot spots'' where drums and hazardous material may have been buried. The technologies addressed by the R ampersand D will benefit all of these activities

  3. Population-Level Incidence and Predictors of Surgically Induced Diabetes and Exocrine Insufficiency after Partial Pancreatic Resection.

    Science.gov (United States)

    Elliott, Irmina A; Epelboym, Irene; Winner, Megan; Allendorf, John D; Haigh, Philip I

    2017-01-01

    Endocrine and exocrine insufficiency after partial pancreatectomy affect quality of life, cardiovascular health, and nutritional status. However, their incidence and predictors are unknown. To identify the incidence and predictors of new-onset diabetes and exocrine insufficiency after partial pancreatectomy. We retrospectively reviewed 1165 cases of partial pancreatectomy, performed from 1998 to 2010, from a large population-based database. Incidence of new onset diabetes and exocrine insufficiency RESULTS: Of 1165 patients undergoing partial pancreatectomy, 41.8% had preexisting diabetes. In the remaining 678 patients, at a median 3.6 months, diabetes developed in 274 (40.4%) and pancreatic insufficiency developed in 235 (34.7%) patients. Independent predictors of new-onset diabetes were higher Charlson Comorbidity Index (CCI; hazard ratio [HR] = 1.62 for CCI of 1, p = 0.02; HR = 1.95 for CCI ≥ 2, p pancreatitis (HR = 1.51, p = 0.03). There was no difference in diabetes after Whipple procedure vs distal pancreatic resections, or malignant vs benign pathologic findings. Independent predictors of exocrine insufficiency were female sex (HR = 1.32, p = 0.002) and higher CCI (HR = 1.85 for CCI of 1, p insufficiency (HR = 0.35, p endocrine and exocrine insufficiency were 40% and 35%, respectively. These data are critical for informing patients' and physicians' expectations.

  4. Pharmaceutical companies and their drugs on social media: a content analysis of drug information on popular social media sites.

    Science.gov (United States)

    Tyrawski, Jennifer; DeAndrea, David C

    2015-06-01

    Many concerns have been raised about pharmaceutical companies marketing their drugs directly to consumers on social media. This form of direct-to-consumer advertising (DTCA) can be interactive and, because it is largely unmonitored, the benefits of pharmaceutical treatment could easily be overemphasized compared to the risks. Additionally, nonexpert consumers can share their own drug product testimonials on social media and illegal online pharmacies can market their services on popular social media sites. There is great potential for the public to be exposed to misleading or dangerous information about pharmaceutical drugs on social media. Our central aim was to examine how pharmaceutical companies use social media to interact with the general public and market their drugs. We also sought to analyze the nature of information that appears in search results for widely used pharmaceutical drugs in the United States on Facebook, Twitter, and YouTube with a particular emphasis on the presence of illegal pharmacies. Content analyses were performed on (1) social media content on the Facebook, Twitter, and YouTube accounts of the top 15 pharmaceutical companies in the world and (2) the content that appears when searching on Facebook, Twitter, and YouTube for the top 20 pharmaceutical drugs purchased in the United States. Notably, for the company-specific analysis, we examined the presence of information similar to various forms of DTCA, the audience reach of company postings, and the quantity and quality of company-consumer interaction. For the drug-specific analysis, we documented the presence of illegal pharmacies, personal testimonials, and drug efficacy claims. From the company-specific analysis, we found information similar to help-seeking DTCA in 40.7% (301/740) of pharmaceutical companies' social media posts. Drug product claims were present in only 1.6% (12/740) of posts. Overall, there was a substantial amount of consumers who interacted with pharmaceutical

  5. Pharmaceutical Companies and Their Drugs on Social Media: A Content Analysis of Drug Information on Popular Social Media Sites

    Science.gov (United States)

    2015-01-01

    Background Many concerns have been raised about pharmaceutical companies marketing their drugs directly to consumers on social media. This form of direct-to-consumer advertising (DTCA) can be interactive and, because it is largely unmonitored, the benefits of pharmaceutical treatment could easily be overemphasized compared to the risks. Additionally, nonexpert consumers can share their own drug product testimonials on social media and illegal online pharmacies can market their services on popular social media sites. There is great potential for the public to be exposed to misleading or dangerous information about pharmaceutical drugs on social media. Objective Our central aim was to examine how pharmaceutical companies use social media to interact with the general public and market their drugs. We also sought to analyze the nature of information that appears in search results for widely used pharmaceutical drugs in the United States on Facebook, Twitter, and YouTube with a particular emphasis on the presence of illegal pharmacies. Methods Content analyses were performed on (1) social media content on the Facebook, Twitter, and YouTube accounts of the top 15 pharmaceutical companies in the world and (2) the content that appears when searching on Facebook, Twitter, and YouTube for the top 20 pharmaceutical drugs purchased in the United States. Notably, for the company-specific analysis, we examined the presence of information similar to various forms of DTCA, the audience reach of company postings, and the quantity and quality of company-consumer interaction. For the drug-specific analysis, we documented the presence of illegal pharmacies, personal testimonials, and drug efficacy claims. Results From the company-specific analysis, we found information similar to help-seeking DTCA in 40.7% (301/740) of pharmaceutical companies’ social media posts. Drug product claims were present in only 1.6% (12/740) of posts. Overall, there was a substantial amount of consumers

  6. Development of an administrative record system and information repository system to support environmental cleanup at the Hanford Site in Richland, Washington

    International Nuclear Information System (INIS)

    Sprouse, B.S.

    1991-09-01

    The purpose of this paper is to describe the development of an administrative record (AR) file system for the Hanford Site in Richland, Washington. This paper will focus on the background of the AR system and its implementation at the Hanford Site; the types of documents to be included in an AR file; the management system used to develop and implement the AR system; the unique characteristics of the AR system and the role of the information repositories. The objective of this session is to present the methodology used in developing an AR and information repository system so that common hurdles from various sites can be addressed and resolved similarly. Therefore unnecessary effort does not have to be put forth to resolve the same issues over and over again. The concepts described can be applied to all federal facility sites with a minimum amount of modification and revision. 9 refs

  7. Particle Physics Education Sites

    Science.gov (United States)

    back to home page Particle Physics Education Sites quick reference Education and Information - National Laboratory Education Programs - Women and Minorities in Physics - Other Physics Sites - Physics Alliance - Accelerators at National Laboratories icon Particle Physics Education and Information sites: top

  8. Application of EnviroTRADE information system for the cleanup of the former Soviet Union (FSU) site at Komarom Base, Hungary

    International Nuclear Information System (INIS)

    Matalucci, R.V.; Harrington, M.W.; Harlan, C.P.; Kuperberg, J.M.; Biczo, I.L.

    1994-01-01

    During a NATO Advanced Research Workshop (ARW) held in Visegrad, Hungary, June 21-23, 1994, portions of contamination data from the Former Soviet Union (FSU) site at Komarom, Hungary were used to demonstrate the international EnviroTRADE Information System as a tool to assist with the identification of alternative cleanup measures for contaminated sites. The NATO ARW was organized and conducted by the joint Florida State University and the Technical University of Budapest, Center for Hungarian-American Environmental Research, Studies, and Exchanges (CHAERSE). The purpose of the workshop was to develop a strategy for the identification and selection of appropriate low-cost and innovative site remediation technologies and approaches for a typical abandoned FSU site. The EnviroTRADE information system is a graphical, photographical, and textual environmental management tool under development by the U.S. Department of Energy (USDOE) at Sandia National Laboratories (SNL) as a part of the cleanup program of the nuclear weapons complex. EnviroTRADE provides a single, powerful, multi-purpose, multi-user, multi-media, and interactive computer information system for worldwide environmental restoration and waste management (ER/WM). Graphical, photographic, and textual data from the Komarom FSU site were entered into EnviroTRADE. These data were used to make comparative evaluations of site characterization and remediation technologies that might be used to clean up primarily hydrocarbon contamination in the groundwater and soil. Available Hydrogeological and geological features, contaminated soil profiles, and topographical maps were included in the information profiles. Although EnviroTRADE is currently only partially populated (approximately 350 technologies for cleanup are included in the database), the utility of the information system to evaluate possible options for cleanup of the Komarom site has been demonstrated

  9. Progress in evaluation of radionuclide geochemical information developed by DOE high-level nuclear waste repository site projects. Annual report, October 1984-September 1985. Volume 4

    International Nuclear Information System (INIS)

    Meyer, R.E.; Arnold, W.D.; Blencoe, J.G.; Jacobs, G.K.; Kelmers, A.D.; Seeley, F.G.; Whatley, S.K.

    1986-05-01

    Information pertaining to the potential geochemical behavior of radionuclides at candidate sites for a high-level radioactive waste repository, which is being developed by projects within the Department of Energy (DOE), is being evaluated by Oak Ridge National Laboratory for the Nuclear Regulatory Commission (NRC). During this report period, emphasis was placed on the evaluation of information pertinent to the Hanford site in southeastern Washington. Results on the sorption/solubility behavior of technetium, neptunium, and uranium in the basalt/water geochemical system are summarized and compared to the results of DOE. Also, summaries of results are reported from two geochemical modeling studies: (1) an evaluation of the information developed by DOE on the native copper deposits of Michigan as a natural analog for the emplacement of copper canisters in a repository in basalt, and (2) calculation of the solubility and speciation of radionuclides for representative groundwaters from the Yucca Mountain site in Nevada

  10. Corrective Action Investigation Plan for Corrective Action Unit 139: Waste Disposal Sites, Nevada Test Site, Nevada

    International Nuclear Information System (INIS)

    Grant Evenson

    2006-01-01

    Corrective Action Unit (CAU) 139 is located in Areas 3, 4, 6, and 9 of the Nevada Test Site, which is 65 miles northwest of Las Vegas, Nevada. Corrective Action Unit 139 is comprised of the seven corrective action sites (CASs) listed below: (1) 03-35-01, Burn Pit; (2) 04-08-02, Waste Disposal Site; (3) 04-99-01, Contaminated Surface Debris; (4) 06-19-02, Waste Disposal Site/Burn Pit; (5) 06-19-03, Waste Disposal Trenches; (6) 09-23-01, Area 9 Gravel Gertie; and (7) 09-34-01, Underground Detection Station. These sites are being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives with the exception of CASs 09-23-01 and 09-34-01. Regarding these two CASs, CAS 09-23-01 is a gravel gertie where a zero-yield test was conducted with all contamination confined to below ground within the area of the structure, and CAS 09-34-01 is an underground detection station where no contaminants are present. Additional information will be obtained by conducting a corrective action investigation (CAI) before evaluating corrective action alternatives and selecting the appropriate corrective action for the other five CASs where information is insufficient. The results of the field investigation will support a defensible evaluation of viable corrective action alternatives that will be presented in the Corrective Action Decision Document. The sites will be investigated based on the data quality objectives (DQOs) developed on January 4, 2006, by representatives of the Nevada Division of Environmental Protection; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and Bechtel Nevada. The DQO process was used to identify and define the type, amount, and quality of data needed to develop and evaluate appropriate corrective actions for CAU 139

  11. Corrective Action Investigation Plan for Corrective Action Unit 137: Waste Disposal Sites, Nevada Test Site, Nevada

    International Nuclear Information System (INIS)

    Wickline, Alfred

    2005-01-01

    This Corrective Action Investigation Plan (CAIP) contains project-specific information including facility descriptions, environmental sample collection objectives, and criteria for conducting site investigation activities at Corrective Action Unit (CAU) 137: Waste Disposal Sites. This CAIP has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense. Corrective Action Unit 137 contains sites that are located in Areas 1, 3, 7, 9, and 12 of the Nevada Test Site (NTS), which is approximately 65 miles (mi) northwest of Las Vegas, Nevada (Figure 1-1). Corrective Action Unit 137 is comprised of the eight corrective action sites (CASs) shown on Figure 1-1 and listed below: (1) CAS 01-08-01, Waste Disposal Site; (2) CAS 03-23-01, Waste Disposal Site; (3) CAS 03-23-07, Radioactive Waste Disposal Site; (4) CAS 03-99-15, Waste Disposal Site; (5) CAS 07-23-02, Radioactive Waste Disposal Site; (6) CAS 09-23-07, Radioactive Waste Disposal Site; (7) CAS 12-08-01, Waste Disposal Site; and (8) CAS 12-23-07, Waste Disposal Site. The Corrective Action Investigation (CAI) will include field inspections, radiological surveys, geophysical surveys, sampling of environmental media, analysis of samples, and assessment of investigation results, where appropriate. Data will be obtained to support corrective action alternative evaluations and waste management decisions. The CASs in CAU 137 are being investigated because hazardous and/or radioactive constituents may be present in concentrations that could potentially pose a threat to human health and the environment. Existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives for the CASs. Additional information will be generated by conducting a CAI before evaluating and selecting corrective action

  12. DbPTM 3.0: an informative resource for investigating substrate site specificity and functional association of protein post-translational modifications.

    Science.gov (United States)

    Lu, Cheng-Tsung; Huang, Kai-Yao; Su, Min-Gang; Lee, Tzong-Yi; Bretaña, Neil Arvin; Chang, Wen-Chi; Chen, Yi-Ju; Chen, Yu-Ju; Huang, Hsien-Da

    2013-01-01

    Protein modification is an extremely important post-translational regulation that adjusts the physical and chemical properties, conformation, stability and activity of a protein; thus altering protein function. Due to the high throughput of mass spectrometry (MS)-based methods in identifying site-specific post-translational modifications (PTMs), dbPTM (http://dbPTM.mbc.nctu.edu.tw/) is updated to integrate experimental PTMs obtained from public resources as well as manually curated MS/MS peptides associated with PTMs from research articles. Version 3.0 of dbPTM aims to be an informative resource for investigating the substrate specificity of PTM sites and functional association of PTMs between substrates and their interacting proteins. In order to investigate the substrate specificity for modification sites, a newly developed statistical method has been applied to identify the significant substrate motifs for each type of PTMs containing sufficient experimental data. According to the data statistics in dbPTM, >60% of PTM sites are located in the functional domains of proteins. It is known that most PTMs can create binding sites for specific protein-interaction domains that work together for cellular function. Thus, this update integrates protein-protein interaction and domain-domain interaction to determine the functional association of PTM sites located in protein-interacting domains. Additionally, the information of structural topologies on transmembrane (TM) proteins is integrated in dbPTM in order to delineate the structural correlation between the reported PTM sites and TM topologies. To facilitate the investigation of PTMs on TM proteins, the PTM substrate sites and the structural topology are graphically represented. Also, literature information related to PTMs, orthologous conservations and substrate motifs of PTMs are also provided in the resource. Finally, this version features an improved web interface to facilitate convenient access to the resource.

  13. Avaliação da acessibilidade de sites oficiais de pesquisa no Brasil por pessoas com deficiência Accessibiblity analyses of digital information for disabled people in the brazilian governanmente web sites

    Directory of Open Access Journals (Sweden)

    José Oscar Fontanini de Carvalho

    2008-10-01

    Full Text Available Apresenta trabalho baseado na revisão da literatura, sobre os temas Sociedade da Informação; Interação Humano-Computador e Inclusão Digital sob a ótica da Ciência da Informação. Constitui-se da avaliação de sites oficiais de órgãos brasileiros de fomento à pesquisa, escolhidos dentre as unidades federativas mais e menos incluídas digitalmente, segundo dados do Mapa da Exclusão Digital, elaborado pela Fundação Getúlio Vargas. Buscou-se averiguar se esses sites estão cumprindo a legislação a respeito da acessibilidade para as pessoas com deficiência. O trabalho possibilitou inferir que os sites oficiais de pesquisa destinados à prestação de serviços públicos e disseminação de informação na web analisados, ainda não são efetivamente acessíveis a todos os cidadãos, de modo a realizar oprincípio da universalização da informação. This article is aimed at presenting a work based upon literature revision in the following areas: Information Society, Interaction Human-Computer and Digital Inclusion in the eyes ofInformation Science. It is about an evaluation of Brazilian Government research sites, which were selected among federative entities with high and low degree of digital inclusion, taking intoaccount the data of Digital Exclusion Map of Fundação Getúlio Vargas. In short, this work shows that the research sites designed to offer public service and disseminate information in theweb are still ineffective in terms of universalization of information.

  14. Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information

    DEFF Research Database (Denmark)

    Hebsgaard, Stefan M.; Korning, Peter G.; Tolstrup, Niels

    1996-01-01

    Artificial neural networks have been combined with a rule based system to predict intron splice sites in the dicot plant Arabidopsis thaliana. A two step prediction scheme, where a global prediction of the coding potential regulates a cutoff level for a local predicition of splice sites, is refin...

  15. [Physiotherapy in outpatients with osteoporosis. Insufficient evidence for therapy success].

    Science.gov (United States)

    Lange, U; Müller-Ladner, U; Teichmann, J

    2012-06-01

    This prospective study analyzed the quality and number of physiotherapeutic reports, the cooperation between physiotherapists and rheumatologists/osteologists as well as the correctness of the physiotherapy in relation to the respective prescription within the German medical healthcare system. Furthermore, it was evaluated whether reported information is sufficient to evaluate outpatient physiotherapy. In 475 physiotherapeutic prescriptions for conservative treatment of patients with osteoporosis, the report quality was evaluated prospectively. The types of prescription and actually performed physiotherapy were compared. The ability of the patients to demonstrate the exercises, as had to be learned during therapy, was analyzed and also the number of mandatory documented questioned follow-up forms. Furthermore, the efficiency of different types of physiotherapy was evaluated. Only 46 reports from 475 prescriptions were received, i.e., the obligation to report was performed only in 9.7% of the cases. Depending on the type of physiotherapy, there was a different range in reporting (classical massage 6.8%, thermotherapy 12.8%, active muscle training with weights and resistant exercises or in water 9.1-20.4% and electrical field treatment 20%). In 141 prescriptions the patients should have learned to do the exercises by themselves as a home program. However, only 38 patients (27%) were able to demonstrate this at the reassessment appointment. In addition in 38 cases of the 46 reports, i.e. in 82.6%, the physiotherapist asked for another prescription. The data illustrate that for outpatient treatment of osteoporosis patients there is insufficient cooperation between physiotherapists and rheumatologists and/or osteologists. Owing to this shortcoming, the efficiency of physiotherapy could not be evaluated due to lack of prescription reports. Therefore, new control mechanisms as well as sufficient education in prescription of physiotherapy should be implemented.

  16. Mean Platelet Volume in Patients with Chronic Venous Insufficiency

    Directory of Open Access Journals (Sweden)

    Mehmet Akif Sarıca

    2016-03-01

    Full Text Available Objective: the mean platelet volume (MPV is a good indicator of platelet activity; it is reported to increase in diseases associated with inflammatory processes and in vascular diseases. This study investigated the importance of mean platelet volume in patients with chronic venous insufficiency (CVI and whether the MPV was likely to be a predictor of the CVI. Methods: 117 patients who were diagnosed as CVI by colored Doppler Ultrasound (CDU method and 49 healthy volunteers (forming the control group were en­rolled to this study, which was planned retrospectively. The patients’ blood count values taken within one month before and after the CDU evaluation were recorded by the hospital information system. The complete blood count, routine biochemical tests and thyroid function tests of the patients diagnosed with CVI were compared to the control group. Results: Significant differences were not detected be­tween the patients and the control group in terms of the levels of creatinine, aspartate aminotransferase, total cholesterol, LDL cholesterol, HDL cholesterol, triglycer­ides, erythrocyte, sedimentation speed, leukocyte, hae­moglobin and thrombocyte (p>0.05. The thyroid stimulat­ing hormone and the MPV levels were significantly lower in the control group (p<0.05. Conclusion: MPV levels as an easy, cheap and practi­cal data extracted from complete blood count, were found higher in patients diagnosed with CVI compared to the control group. This may be originated from endothelium changes as an answer to venous hypertension and dila­tation in CVI. MPV can be used as a follow-up marker in CVI patients. J Clin Exp Invest 2016; 7 (1: 73-77

  17. Information needs for characterization of high-level waste repository sites in six geologic media. Volume 2. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1985-05-01

    Volume II contains appendices for the following: (1) remote sensing and surface mapping techniques; (2) subsurface mapping methods for site characterization; (3) gravity technique; (4) audio-frequency magnetotelluric technique; (5) seismic refraction technique; (6) direct-current electrical resistivity method; (7) magnetic technique; (8) seismic reflection technique; (9) seismic crosshole method; (10) mechanical downhole seismic velocity survey method; (11) borehole geophysical logging techniques; (12) drilling and coring methods for precharacterization studies; (13) subsurface drilling methods for site characterization; (14) geomechanical/thermomechanical techniques for precharacterization studies; (15)geomechanical/thermal techniques for site characterization studies; (16) exploratory geochemical techniques for precharacterization studies; (17) geochemical techniques for site characterization; (18) hydrologic techniques for precharacterization studies; (19) hydrologic techniques for site characterization; and (20) seismological techniques.

  18. Information needs for characterization of high-level waste repository sites in six geologic media. Volume 2. Appendices

    International Nuclear Information System (INIS)

    1985-05-01

    Volume II contains appendices for the following: (1) remote sensing and surface mapping techniques; (2) subsurface mapping methods for site characterization; (3) gravity technique; (4) audio-frequency magnetotelluric technique; (5) seismic refraction technique; (6) direct-current electrical resistivity method; (7) magnetic technique; (8) seismic reflection technique; (9) seismic crosshole method; (10) mechanical downhole seismic velocity survey method; (11) borehole geophysical logging techniques; (12) drilling and coring methods for precharacterization studies; (13) subsurface drilling methods for site characterization; (14) geomechanical/thermomechanical techniques for precharacterization studies; (15)geomechanical/thermal techniques for site characterization studies; (16) exploratory geochemical techniques for precharacterization studies; (17) geochemical techniques for site characterization; (18) hydrologic techniques for precharacterization studies; (19) hydrologic techniques for site characterization; and (20) seismological techniques

  19. MRI of occult sacral insufficiency fractures following radiotherapy

    International Nuclear Information System (INIS)

    Mammone, J.F.; Schweitzer, M.E.

    1995-01-01

    Following radiation therapy, marrow abnormalities noted on magnetic resonance imaging (MRI) are frequent and may mimic metastases. Specific radiotherapy changes are usually easily identifiable; however, traumatic lesions cause more interpretive difficulties. We assessed the incidence and MRI characteristics of insufficiency fractures in this population. During a 5-year span (1987-1991), 546 patients received pelvic radiotherapy for primary malignancies. MRI was performed in 25 of these patients at least 3 months after treatment. The mean dose in this group was 53 Gy. These MRI scans were retrospectively reviewed for the appearance of the sacrum with particular attention to the presence of insufficiency fractures. This was correlated with clinical course and scintigraphic findings. Presumed insufficiency fractures on MRI paralleled the sacral side of the sacroiliac joint, enhanced with Gd-DTPA, were most prominent or initially seen anteriorly, and had ill-defined margins on all imaging sequences. The incidence of occult sacral insufficiency fractures was at least 20%. Insufficiency fractures of the sacrum in the post-radiotherapy patient are a relatively frequent occurrence which can mimic metastases. Consideration of this phenomenon and knowledge of differential features may avoid overdiagnosis of osseous metastases. (orig.)

  20. Why Sleep Matters—The Economic Costs of Insufficient Sleep

    Science.gov (United States)

    Hafner, Marco; Stepanek, Martin; Taylor, Jirka; Troxel, Wendy M.; van Stolk, Christian

    2017-01-01

    Abstract The Centers for Disease Control and Prevention (CDC) in the United States has declared insufficient sleep a “public health problem.” Indeed, according to a recent CDC study, more than a third of American adults are not getting enough sleep on a regular basis. However, insufficient sleep is not exclusively a US problem, and equally concerns other industrialised countries such as the United Kingdom, Japan, Germany, or Canada. According to some evidence, the proportion of people sleeping less than the recommended hours of sleep is rising and associated with lifestyle factors related to a modern 24/7 society, such as psychosocial stress, alcohol consumption, smoking, lack of physical activity and excessive electronic media use, among others. This is alarming as insufficient sleep has been found to be associated with a range of negative health and social outcomes, including success at school and in the labour market. Over the last few decades, for example, there has been growing evidence suggesting a strong association between short sleep duration and elevated mortality risks. Given the potential adverse effects of insufficient sleep on health, well-being and productivity, the consequences of sleep-deprivation have far-reaching economic consequences. Hence, in order to raise awareness of the scale of insufficient sleep as a public-health issue, comparative quantitative figures need to be provided for policy- and decision-makers, as well as recommendations and potential solutions that can help tackling the problem. PMID:28983434

  1. Predictive factors for exocrine pancreatic insufficiency after pancreatoduodenectomy with pancreaticogastrostomy.

    Science.gov (United States)

    Nakamura, Hiroyuki; Murakami, Yoshiaki; Uemura, Kenichiro; Hayashidani, Yasuo; Sudo, Takeshi; Ohge, Hiroki; Sueda, Taijiro

    2009-07-01

    The aim of this study was to determine risk factors for exocrine pancreatic insufficiency after pancreatoduodenectomy (PD) with pancreaticogastrostomy (PG). A (13)C-labeled mixed triglyceride breath test was performed in 61 patients after PD to assess exocrine pancreatic function. Percent (13)CO(2) cumulative dose at 7 h pancreatic insufficiency. Abdominal computed tomography scans were utilized to assess the dilatation of the main pancreatic duct (MPD dilatation) in the remnant. Thirty-eight of 61 patients (62.3%) were diagnosed with exocrine pancreatic insufficiency. Univariate analysis identified significant associations between two preoperative factors (preoperative impaired endocrine function and a hard pancreatic texture induced by preexisting obstructive pancreatitis), plus one postoperative factor (MPD dilatation caused by PG stricture) and exocrine pancreatic insufficiency (P pancreatic insufficiency after PD may be partly explainable by preexisting obstructive pancreatitis prior to surgery, surgeons desiring to obtain better postoperative exocrine pancreatic function after PD would be well-advised to devote considerable attention to preventing PG stricture.

  2. Key Determinant Derivations for Information Technology Disaster Recovery Site Selection by the Multi-Criterion Decision Making Method

    Directory of Open Access Journals (Sweden)

    Chia-Lee Yang

    2015-05-01

    Full Text Available Disaster recovery sites are an important mechanism in continuous IT system operations. Such mechanisms can sustain IT availability and reduce business losses during natural or human-made disasters. Concerning the cost and risk aspects, the IT disaster-recovery site selection problems are multi-criterion decision making (MCDM problems in nature. For such problems, the decision aspects include the availability of the service, recovery time requirements, service performance, and more. The importance and complexities of IT disaster recovery sites increases with advances in IT and the categories of possible disasters. The modern IT disaster recovery site selection process requires further investigation. However, very few researchers tried to study related issues during past years based on the authors’ extremely limited knowledge. Thus, this paper aims to derive the aspects and criteria for evaluating and selecting a modern IT disaster recovery site. A hybrid MCDM framework consisting of the Decision Making Trial and Evaluation Laboratory (DEMATEL and the Analytic Network Process (ANP will be proposed to construct the complex influence relations between aspects as well as criteria and further, derive weight associated with each aspect and criteria. The criteria with higher weight can be used for evaluating and selecting the most suitable IT disaster recovery sites. In the future, the proposed analytic framework can be used for evaluating and selecting a disaster recovery site for data centers by public institutes or private firms.

  3. Use of integrated geologic and geophysical information for characterizing the structure of fracture systems at the US/BK Site, Grimsel Laboratory, Switzerland

    International Nuclear Information System (INIS)

    Martel, S.J.; Peterson, J.E. Jr.

    1990-05-01

    Fracture systems form the primary fluid flow paths in a number of rock types, including some of those being considered for high level nuclear waste repositories. In some cases, flow along fractures must be modeled explicitly as part of a site characterization effort. Fractures commonly are concentrated in fracture zones, and even where fractures are seemingly ubiquitous, the hydrology of a site can be dominated by a few discrete fracture zones. We have implemented a site characterization methodology that combines information gained from geophysical and geologic investigations. The general philosophy is to identify and locate the major fracture zones, and then to characterize their systematics. Characterizing the systematics means establishing the essential and recurring patterns in which fractures are organized within the zones. We make a concerted effort to use information on the systematics of the fracture systems to link the site-specific geologic, borehole and geophysical information. This report illustrates how geologic and geophysical information on geologic heterogeneities can be integrated to guide the development of hydrologic models. The report focuses on fractures, a particularly common type of geologic heterogeneity. However, many aspects of the methodology we present can be applied to other geologic heterogeneities as well. 57 refs., 40 figs., 1 tab

  4. Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment.

    Science.gov (United States)

    Bachmann, Gloria; Bancroft, John; Braunstein, Glenn; Burger, Henry; Davis, Susan; Dennerstein, Lorraine; Goldstein, Irwin; Guay, Andre; Leiblum, Sandra; Lobo, Rogerio; Notelovitz, Morris; Rosen, Raymond; Sarrel, Philip; Sherwin, Barbara; Simon, James; Simpson, Evan; Shifren, Jan; Spark, Richard; Traish, Abdul

    2002-04-01

    To evaluate the evidence for and against androgen insufficiency as a cause of sexual and other health-related problems in women and to make recommendations regarding definition, diagnosis, and assessment of androgen deficiency states in women. Evaluation of peer-review literature and consensus conference of international experts. Multinational conference in the United States. Premenopausal and postmenopausal women with androgen deficiency. Evaluation of peer-review literature and development of consensus panel guidelines. The term "female androgen insufficiency" was defined as consisting of a pattern of clinical symptoms in the presence of decreased bioavailable T and normal estrogen status. Currently available assays were found to be lacking in sensitivity and reliability at the lower ranges, and the need for an equilibrium dialysis measure was strongly emphasized. Causes of androgen insufficiency in women were classified as ovarian, adrenal, hypothalamic-pituitary, drug-related, and idiopathic. A simplified management algorithm and clinical guidelines were proposed to assist clinicians in diagnosis and assessment. Androgen replacement is currently available in several forms, although none has been approved for treatment of sexual dysfunction or other common symptoms of female androgen insufficiency. Potential risks associated with treatment were identified, and the need for informed consent and careful monitoring was noted. Finally, the panel identified key goals and priorities for future research. A new definition of androgen insufficiency in women has been proposed along with consensus-based guidelines for clinical assessment and diagnosis. A simplified management algorithm for women with low androgen in the presence of clinical symptoms and normal estrogen status has also been proposed.

  5. Visualization of traumatic tricuspid insufficiency by three-dimensional echocardiography.

    Science.gov (United States)

    Nishimura, Kazuhisa; Okayama, Hideki; Inoue, Katsuji; Saito, Makoto; Nagai, Takayuki; Suzuki, Jun; Ogimoto, Akiyoshi; Ohtsuka, Tomoaki; Higaki, Jitsuo

    2010-01-01

    A 19-year-old male was admitted to the emergency room of our hospital after a motor vehicle accident. During his first physical examination, a holosystolic murmur was heard at the fourth left parasternal border. Transthoracic echocardiography showed severe tricuspid insufficiency, but the cause of tricuspid insufficiency was unclear. Therefore, three-dimensional echocardiography was performed and demonstrated flail anterior, posterior and septal leaflets of the tricuspid valve. The diagnosis was tricuspid insufficiency due to papillary muscle rupture secondary to chest blunt trauma. Surgical repair of the tricuspid valve was performed in this patient. After surgery, the signs and symptoms of right ventricular heart failure were relieved. In this case, three-dimensional echocardiography was very useful for the evaluation of spatial destruction of the tricuspid valve and papillary muscle. 2009 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  6. MR appearance of parasymphyseal insufficiency fractures of the os pubis

    Energy Technology Data Exchange (ETDEWEB)

    Hosono, Mariko; Fujimoto, Ryota; Konishi, Junji [Department of Nuclear Medicine, Faculty of Medicine, Kyoto University, 54 Shogoin-kawahara-cho, Sakyo-ku, Kyoto (Japan); Kobayashi, Hisataka [Nulcear Medicine Department, National Institutes of Health, Building 10, Room 1C-401, Bethesda, MD 20892 (United States); Tsutsui, Kazushige [Department of Radiology, Japanese Red Cross Society Wakayama Medical Center, Wakayama (Japan); Kotoura, Yoshihiko [Department of Orthopaedic Surgery, Nagahama City Hospital, Nagahama, Shiga (Japan); Tsuboyama, Tadao; Nakamura, Takashi [Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Kyoto (Japan); Hayashi, Hikaru [Department of Orthopaedic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama (Japan)

    1997-09-01

    Objective. To clarify the MRI features of parasymphyseal insufficiency fractures of the os pubis. Design and patients. MRI was performed in four postmenopausal women with parasymphyseal insufficiency fractures. The diagnosis was confirmed with plain films in every patient. T1-weighted and T2-weighted images were obtained in four patients using a 1.5-T unit. Postcontrast T1-weighted imaging was also done in three patients. Results and conclusions. MRI of pubic parasymphyseal insufficiency fracture characteristically demonstrates a hyperintense mass lesion with a hypointense rim on T2-weighted imaging, showing peripheral and septal enhancement after contrast administration. It is important to have this entity in mind in patients with osteoporosis, especially in patients with a history of pelvic irradiation for malignant disease, so as not to misinterpret it as a chondroid tumor or bone metastasis. (orig.). With 2 figs., 2 tabs.

  7. Chronic workplace stress and insufficient physical activity: a cohort study.

    Science.gov (United States)

    Kouvonen, Anne; Vahtera, Jussi; Oksanen, Tuula; Pentti, Jaana; Väänänen, Ari K P; Heponiemi, Tarja; Salo, Paula; Virtanen, Marianna; Kivimäki, Mika

    2013-01-01

    To examine whether exposure to workplace stressors predicts changes in physical activity and the risk of insufficient physical activity. Prospective data from the Finnish Public Sector Study. Repeated exposure to low job control, high job demands, low effort, low rewards and compositions of these (job strain and effort-reward imbalance) were assessed at Time 1 (2000-2002) and Time 2 (2004). Insufficient physical activity (workplace stressors on change in physical activity was examined using fixed-effects (within-subject) logistic regression models (N=6665). In addition, logistic regression analysis was applied to examine the associations between repeated exposure to workplace stressors and insufficient physical activity (N=13 976). In these analyses, coworker assessed workplace stressor scores were used in addition to individual level scores. The proportion of participants with insufficient physical activity was 24% at baseline and 26% at follow-up. 19% of the participants who were sufficiently active at baseline became insufficiently active at follow-up. In the fixed-effect analysis, an increase in workplace stress was weakly related to an increase in physical inactivity within an individual. In between-subjects analysis, employees with repeated exposure to low job control and low rewards were more likely to be insufficiently active at follow-up than those with no reports of these stressors; fully adjusted ORs ranged from 1.11 (95% CI 1.00 to 1.24) to 1.21 (95% CI 1.05 to 1.39). Workplace stress is associated with a slightly increased risk of physical inactivity.

  8. Clinical significance of gamma camera renography in chronic renal insufficiency

    International Nuclear Information System (INIS)

    Dudczak, R.; Frischauf, H.; Kletter, K.

    1980-01-01

    Gamma camera renography allows, together with renal imaging, an evaluation of individual renal function. For these examinations, I 123 orthoiodohippurate is preferred and most widely used. The results on patients with chronic renal insufficiency, including urologic and posttransplantation patients, are reported. Whereas the method is of clinical significance in evaluating posttransplantation complications and in assessing individual kidney function preoperatively in urology, as well as in monitoring therapeutic effects in the early period of renal disease, it is of limited diagnostic value in chronic renal insufficiency. In this latter regard, clinical and laboratory examinations are of primary importance. (author)

  9. Vitamin D Insufficiency among Free-Living Healthy Young Adults

    OpenAIRE

    Tangpricha, Vin; Pearce, Elizabeth N.; Chen, Tai C.; Holick, Michael F.

    2002-01-01

    Long-term vitamin D insufficiency can cause secondary hyperparathyroidism and osteomalacia (1). In addition, there is increasing evidence that vitamin D may protect against common cancers, such as cancer of the colon (2–4), prostate (5), and breast (6). Young adults aged 17 to 35 years drink inadequate amounts of milk (7) and are concerned about exposure to the sun because of the fear of developing skin cancer (8,9), which increases the risk of vitamin D insufficiency (10). We sought to exami...

  10. Site-specific assessments of the abundance of three inshore dolphin species to inform conservation and management

    Directory of Open Access Journals (Sweden)

    Alexander Mark Brown

    2016-02-01

    Full Text Available Assessing the abundance of wildlife populations is essential to their effective conservation and management. Concerns have been raised over the vulnerability of tropical inshore dolphins in waters off northern Australia to anthropogenic impacts on local populations, yet a lack of abundance data precludes assessment of their conservation status and the management of threats. Using small vessels as cost-effective research platforms, photo-identification surveys and capture-recapture models were applied to provide the first quantitative abundance data for Australian snubfin (Orcaella heinsohni, Australian humpback (Sousa sahulensis, and Indo-Pacific bottlenose dolphins (Tursiops aduncus at five sites in the Kimberley region of north-western Australia. The abundance of each species was highly variable between different sites, likely reflecting species-specific habitat preferences. Within the c. 130 km2 study sites, the estimated abundance of most species was ≤ 60 individuals (excluding calves, and fewer than 20 humpback dolphins were identified at each site in any one 3-5 week sampling period. However, larger estimates of c. 130 snubfin and c. 160 bottlenose dolphins were obtained at two different sites. Several local populations showed evidence of site fidelity, particularly snubfin dolphins. By implementing a standardized, multi-site approach, data on local populations were provided within a broader, regional context, and indicated that each species is patchily distributed in the region. This highlights the need for site-specific baseline data collection using appropriate survey techniques to quantitatively assess the potential impacts of threatening activities to local populations. These findings further illustrate the need to gain a greater understanding of known and potential threats to inshore dolphin populations, their relative impacts, and to mitigate where necessary. In particular, the level of interactions with inshore gillnet fisheries

  11. Establishment of advanced integration technology for site characterization of deep geological repository. Development of information synthesis and interpretation system. Annual report 2007

    International Nuclear Information System (INIS)

    Osawa, Hideaki; Umeki, Hiroyuki; Ota, Kunio; Maekawa, Keisuke; Kunimaru, Takanori; Niizato, Tadafumi; Asamori, Koichi; Yamanaka, Yoshiaki; Shigehiro, Michiko; Abe, Hironobu; Hama, Katsuhiro; Takeuchi, Shinji; Amano, Kenji; Saegusa, Hiromitsu; Matsukawa, Toshiyuki; Miyamoto, Tetsuo; Toyoda, Gakuji; Sawada, Atsushi; Shimada, Akiomi

    2008-11-01

    This project is planned as a five-year program aiming to develop an advanced integration technology for characterization of a site for radioactive waste geological disposal. It is carried out by the Geological Isolation Research and Development Directorate of Japan Atomic Energy Agency with the fund of Agency for Natural Resources and Energy of the Ministry of Economy, Trade and Industry. This report summarizes the outcome of the first year (FY 2007) activities of the project. The site characterization is a dynamic and complex process and needs close linkage with repository design and performance assessment (PA). A geosynthesis methodology has been developed for integrating site characterization information into design and PA, and applied for e.g. on-going JAEA's studies at two generic URLs at Mizunami and Horonobe. This methodology explicitly presents an information flow (often referred to as geosynthesis data flow diagram or data flow diagram, in short) from measurements by site investigation to generating data sets for design and PA. It is a useful tool for guiding the site characterization in a transparent and traceable manner. As site investigation proceeds and information being obtained on geological environments of the site increases, the site characterization plan is iteratively reviewed and modified reflecting the updated information. Such modification would also be needed when changes would occur on socio-political boundary conditions. In fact, the data flow diagrams for two generic URL projects have been revised several times so far due to the increase in the amount of information on geological environments and changes of societal conditions. An advanced technology aimed at in this project is therefore focused on developing flexible approach and tools, which is named as Information Synthesis and Interpretation System (ISIS), to support the stepwise 'optimization' of the site characterization plan. In FY 2007, a basic concept for ISIS has been developed

  12. An Information Technology Framework for the Development of an Embedded Computer System for the Remote and Non-Destructive Study of Sensitive Archaeology Sites

    Directory of Open Access Journals (Sweden)

    Iliya Georgiev

    2017-04-01

    Full Text Available The paper proposes an information technology framework for the development of an embedded remote system for non-destructive observation and study of sensitive archaeological sites. The overall concept and motivation are described. The general hardware layout and software configuration are presented. The paper concentrates on the implementation of the following informational technology components: (a a geographically unique identification scheme supporting a global key space for a key-value store; (b a common method for octree modeling for spatial geometrical models of the archaeological artifacts, and abstract object representation in the global key space; (c a broadcast of the archaeological information as an Extensible Markup Language (XML stream over the Web for worldwide availability; and (d a set of testing methods increasing the fault tolerance of the system. This framework can serve as a foundation for the development of a complete system for remote archaeological exploration of enclosed archaeological sites like buried churches, tombs, and caves. An archaeological site is opened once upon discovery, the embedded computer system is installed inside upon a robotic platform, equipped with sensors, cameras, and actuators, and the intact site is sealed again. Archaeological research is conducted on a multimedia data stream which is sent remotely from the system and conforms to necessary standards for digital archaeology.

  13. Traumatic Tricuspid Insufficiency Requiring Valve Repair in an Acute Setting.

    Science.gov (United States)

    Enomoto, Yoshinori; Sudo, Yoshio; Sueta, Tomonori

    2015-01-01

    Tricuspid insufficiency due to penetrating cardiac trauma is rare. Patients with tricuspid insufficiency due to trauma can tolerate this abnormality for months or even years. We report a case of a 66-year-old female with penetrating cardiac trauma on the right side of her heart that required tricuspid valve repair in an acute setting. She sustained cut and stab wounds on her bilateral forearms and in the neck and epigastric region. She had cardiac tamponade and developed pulseless electrical activity, which required emergency surgery. The right ventricle and superior vena cava were dissected approximately 5 cm and 2 cm, respectively. After these wounds had been repaired, the patient's inability to wean from cardiopulmonary bypass suggested rightsided heart failure; transesophageal echocardiography revealed tricuspid insufficiency. Right atriotomy was performed, and a detailed examination revealed that the tricuspid valve septal leaflet was split in two. There was also an atrial septal injury that created a connection with the left atrium; these injuries were not detected from the right ventricular wound. After repair, weaning from cardiopulmonary bypass with mild tricuspid insufficiency was achieved, and she recovered uneventfully. This case emphasized the importance of thoroughly investigating intracardiac injury and transesophageal echocardiography.

  14. Physiologic AV valvular insufficiency in cine MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Yoon Hyung; Kang, Eun Joo; Baik, Seung Kug; Ahn, Woo Hyun; Choi, Han Yong; Kim, Bong Gi [Wallace Memorial Baptist Hospital, Pusan (Korea, Republic of)

    1994-05-15

    To give a help in the interpretation of cardiac cine-MR examination, the extent, shape, and timing of appearance of signal void regions near atrioventricular(A-V) valve prospectively evaluate in the healthy population. Using an axial gradient-echo technique with small flip angle, repetition time(TR) of 36 msec and echo time(TE) of 22 msec, 20 volunteers without known valvular abnormalities undertook cardiac cine-MR imaging including atrioventricular valve areas. Transient signal void was observed within the near the tricuspid(13/20 = 65%) and mitral valves(9/20 = 45%), respectively, which is so called {sup p}hysioloic atrioventricular valvular insufficiency{sup .} Eight subjects revealed the signal void areas near both tricuspid and mitral valves but, 5 subjects did not show any evidence of physiologic insufficiency. This physiologic condition does not extend more than 1 cm proximal to A-V valve plane and is generally observed only during early systole. Its morphology is semilunar or triangular configuration with the base to the valve plane in most cases of normal tricuspid insufficiency and small globular appearance in most cases of normal mitral insufficiency. Awareness of normal signal void areas near the A-V valve and their characteristics is critical in the interpretation of cardiac cine MR examinations and maybe helpful in the study of the normal cardiac physiology.

  15. Physiologic AV valvular insufficiency in cine MR imaging

    International Nuclear Information System (INIS)

    Jang, Yoon Hyung; Kang, Eun Joo; Baik, Seung Kug; Ahn, Woo Hyun; Choi, Han Yong; Kim, Bong Gi

    1994-01-01

    To give a help in the interpretation of cardiac cine-MR examination, the extent, shape, and timing of appearance of signal void regions near atrioventricular(A-V) valve prospectively evaluate in the healthy population. Using an axial gradient-echo technique with small flip angle, repetition time(TR) of 36 msec and echo time(TE) of 22 msec, 20 volunteers without known valvular abnormalities undertook cardiac cine-MR imaging including atrioventricular valve areas. Transient signal void was observed within the near the tricuspid(13/20 = 65%) and mitral valves(9/20 = 45%), respectively, which is so called p hysioloic atrioventricular valvular insufficiency . Eight subjects revealed the signal void areas near both tricuspid and mitral valves but, 5 subjects did not show any evidence of physiologic insufficiency. This physiologic condition does not extend more than 1 cm proximal to A-V valve plane and is generally observed only during early systole. Its morphology is semilunar or triangular configuration with the base to the valve plane in most cases of normal tricuspid insufficiency and small globular appearance in most cases of normal mitral insufficiency. Awareness of normal signal void areas near the A-V valve and their characteristics is critical in the interpretation of cardiac cine MR examinations and maybe helpful in the study of the normal cardiac physiology

  16. Adrenal insufficiency in critically ill septic patients at Dr George ...

    African Journals Online (AJOL)

    Adele

    eosinophillia and hypoglycemia. Hyponatremia and hyperkalemia are uncommon. There has been much controversy regarding the criteria for the diagnosis of adrenal insufficiency.10,11,12 The diagnosis would be best made using an end-organ marker of adrenal steroid action. No such marker is available at present. Free.

  17. Treatment of insufficient lactation is often not evidence-based

    DEFF Research Database (Denmark)

    Axelsson, Paul Bryde; Bjerrum, Flemming; Løkkegaard, Ellen Christine Leth

    2014-01-01

    INTRODUCTION: Breast milk has many advantages over formula for infants in developed and developing countries alike. Despite intentions of breastfeeding, some women develop insufficient lactation. Treatment options traditionally include breastfeeding education and pharmacotherapy. MATERIAL AND MET...... be initiated by counselling and education. Only when these treatment options are exhausted should pharmacotherapy with a suitable medication be considered. FUNDING: not relevant. TRIAL REGISTRATION: not relevant....

  18. Hydrocortisone dose in adrenal insufficiency : Balancing harms and benefits

    NARCIS (Netherlands)

    Werumeus Buning, Jorien

    2017-01-01

    Patients with secondary adrenal insufficiency do not produce cortisol and are therefore treated with hydrocortisone tablets. The optimal substitution dose for hydrocortisone is unknown. We therefore performed this study, in which two different doses of hydrocortisone and its effect on cognition

  19. Nocturnal foot blood flow in patients with arterial insufficiency

    DEFF Research Database (Denmark)

    Jelnes, Rolf; Tønnesen, K H

    1984-01-01

    Twenty-four hour continuous recording of xenon (133Xe) wash-out from the forefoot was performed on patients with normal circulations (n = 10) and on patients with different degrees of arterial insufficiency (n = 36). During day hours the calculated subcutaneous blood flow in the forefoot was on a...

  20. 29 CFR 541.2 - Job titles insufficient.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Job titles insufficient. 541.2 Section 541.2 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS DEFINING AND DELIMITING THE EXEMPTIONS FOR EXECUTIVE, ADMINISTRATIVE, PROFESSIONAL, COMPUTER AND OUTSIDE SALES EMPLOYEES...

  1. Prevalence and effects of functional vitamin K insufficiency

    NARCIS (Netherlands)

    Riphagen, Ineke J.; Keyzer, Charlotte A.; Drummen, Nadja E.A.; Borst, de Martin H.; Beulens, Joline W.J.; Gansevoort, Ron T.; Geleijnse, Johanna M.; Muskiet, Frits A.J.; Navis, Gerjan; Visser, Sipke T.; Vermeer, Cees; Kema, Ido P.; Bakker, Stephan J.L.

    2017-01-01

    Matrix Gla Protein (MGP) is a strong vitamin K-dependent inhibitor of soft tissue calcification. We assessed the prevalence of functional vitamin K insufficiency, as derived from plasma desphospho-uncarboxylated MGP (dp-ucMGP), and investigated whether plasma dp-ucMGP is associated with all-cause

  2. Health consequences of shift work and insufficient sleep

    NARCIS (Netherlands)

    Kecklund, L.G.; Axelsson, J.

    2016-01-01

    This review summarises the literature on shift work and its relation to insufficient sleep, chronic diseases, and accidents. It is based on 38 meta-analyses and 24 systematic reviews, with additional narrative reviews and articles used for outlining possible mechanisms by which shift work may cause

  3. Health consequences of shift work and insufficient sleep.

    Science.gov (United States)

    Kecklund, Göran; Axelsson, John

    2016-11-01

    This review summarises the literature on shift work and its relation to insufficient sleep, chronic diseases, and accidents. It is based on 38 meta-analyses and 24 systematic reviews, with additional narrative reviews and articles used for outlining possible mechanisms by which shift work may cause accidents and adverse health. Evidence shows that the effect of shift work on sleep mainly concerns acute sleep loss in connection with night shifts and early morning shifts. A link also exists between shift work and accidents, type 2 diabetes (relative risk range 1.09-1.40), weight gain, coronary heart disease (relative risk 1.23), stroke (relative risk 1.05), and cancer (relative risk range 1.01-1.32), although the original studies showed mixed results. The relations of shift work to cardiometabolic diseases and accidents mimic those with insufficient sleep. Laboratory studies indicate that cardiometabolic stress and cognitive impairments are increased by shift work, as well as by sleep loss. Given that the health and safety consequences of shift work and insufficient sleep are very similar, they are likely to share common mechanisms. However, additional research is needed to determine whether insufficient sleep is a causal pathway for the adverse health effects associated with shift work. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  4. Pancreatic fibrosis correlates with exocrine pancreatic insufficiency after pancreatoduodenectomy.

    Science.gov (United States)

    Tran, T C K; van 't Hof, G; Kazemier, G; Hop, W C; Pek, C; van Toorenenbergen, A W; van Dekken, H; van Eijck, C H J

    2008-01-01

    Obstruction of the pancreatic duct can lead to pancreatic fibrosis. We investigated the correlation between the extent of pancreatic fibrosis and the postoperative exocrine and endocrine pancreatic function. Fifty-five patients who were treated for pancreatic and periampullary carcinoma and 19 patients with chronic pancreatitis were evaluated. Exocrine pancreatic function was evaluated by fecal elastase-1 test, while endocrine pancreatic function was assessed by plasma glucose level. The extent of fibrosis, duct dilation and endocrine tissue loss was examined histopathologically. A strong correlation was found between pancreatic fibrosis and elastase-1 level less than 100 microg/g (p pancreatic insufficiency. A strong correlation was found between pancreatic fibrosis and endocrine tissue loss (p pancreatic fibrosis nor endocrine tissue loss were correlated with the development of postoperative diabetes mellitus. Duct dilation alone was neither correlated with exocrine nor with endocrine function loss. The majority of patients develop severe exocrine pancreatic insufficiency after pancreatoduodenectomy. The extent of exocrine pancreatic insufficiency is strongly correlated with preoperative fibrosis. The loss of endocrine tissue does not correlate with postoperative diabetes mellitus. Preoperative dilation of the pancreatic duct per se does not predict exocrine or endocrine pancreatic insufficiency postoperatively. Copyright 2008 S. Karger AG, Basel.

  5. Pancreatic insufficiency after different resections for benign tumours.

    Science.gov (United States)

    Falconi, M; Mantovani, W; Crippa, S; Mascetta, G; Salvia, R; Pederzoli, P

    2008-01-01

    Pancreatic resections for benign diseases may lead to long-term endocrine/exocrine impairment. The aim of this study was to compare postoperative and long-term results after different pancreatic resections for benign disease. Between 1990 and 1999, 62 patients underwent pancreaticoduodenectomy (PD), 36 atypical resection (AR) and 64 left pancreatectomy (LP) for benign tumours. Exocrine and endocrine pancreatic function was evaluated by 72-h faecal chymotrypsin and oral glucose tolerance test. The incidence of pancreatic fistula was significantly higher after AR than after LP (11 of 36 versus seven of 64; P = 0.028). The long-term incidence of endocrine pancreatic insufficiency was significantly lower after AR than after PD (P insufficiency was more common after PD (P endocrine and exocrine insufficiency was higher for PD and LP than for AR (32, 27 and 3 per cent respectively at 1 year; 58, 29 and 3 per cent at 5 years; P pancreatic resections are associated with different risks of developing long-term pancreatic insufficiency. AR represents the best option in terms of long-term endocrine and exocrine function, although it is associated with more postoperative complications. Copyright (c) 2007 British Journal of Surgery Society Ltd.

  6. A new peroxisomal disorder with fetal and neonatal adrenal insufficiency

    NARCIS (Netherlands)

    Vanhole, C.; de Zegher, F.; Casaer, P.; Devlieger, H.; Wanders, R. J.; Vanhove, G.; Jaeken, J.

    1994-01-01

    A boy with a new type of adrenoleukodystrophy is described. This was characterised by fetal and neonatal adrenal insufficiency, a neurological picture as seen in neonatal adrenoleukodystrophy, but with a normal number of peroxisomes in the liver and a peroxisomal dysfunction limited to the very long

  7. Response of geomorphic and geological processes to insufficient ...

    Indian Academy of Sciences (India)

    Depositional models have been constructed for each segment: a constant shelf break model with insufficient sediment supply in the east, and a migration shelf break model with plenty sediment supply in the west. This case study contributes to the understanding of the upper slope sedimentary process and stratigraphic style ...

  8. Information report of AREVA La Hague site, written in compliance with article L. 125-15 of the French environment code - 2015 Edition

    International Nuclear Information System (INIS)

    2016-01-01

    Published in compliance with the French code of the environment, this report presents, first, the Areva La Hague site with its facilities and activities in relation with spent fuel reprocessing and radioactive waste management. Then, it takes stock of the dispositions implemented for the limitation and prevention of risks and summarizes the events declared in 2015. Next, it presents the management of the site effluents and wastes and the environmental monitoring. Finally, the actions of public information are presented. The recommendations of the Health and safety Committee are included in appendix

  9. Information report of AREVA Romans site - 2015 Edition. This report is written in compliance with article L. 125-15 of the French environment code

    International Nuclear Information System (INIS)

    2016-01-01

    Published in compliance with the French code of the environment, this report presents, first, the AREVA Romans site with its facilities and activities in the domain of fuel assembly fabrication. Then, it takes stock of the dispositions implemented for the limitation and prevention of risks and summarizes the events declared in 2015. Next, it presents the management of the site effluents and wastes and the environmental monitoring. Finally, the actions of public information are presented. The recommendations of the Health and safety Committee are included in appendix

  10. Information report of AREVA Malvesi site - 2015 Edition. This report is written in compliance with article L. 125-15 of the French environment code

    International Nuclear Information System (INIS)

    2016-01-01

    Published in compliance with the French code of the environment, this report presents, first, the AREVA Malvesi site with its facilities and activities in the domain of uranium conversion. Then, it takes stock of the dispositions implemented for the limitation and prevention of risks and summarizes the events declared in 2015. Next, it presents the management of the site effluents and wastes and the environmental monitoring. Finally, the actions of public information are presented. The recommendations of the Health and safety Committee are included in appendix

  11. Information report of AREVA Melox site - 2015 Edition. This report is written in compliance with article L. 125-15 of the French environment code

    International Nuclear Information System (INIS)

    2016-01-01

    Published in compliance with the French code of the environment, this report presents, first, the AREVA Melox site with its facilities and activities in the domain of MOX fuel fabrication. Then, it takes stock of the dispositions implemented for the limitation and prevention of risks and summarizes the events declared in 2015. Next, it presents the management of the site effluents and wastes and the environmental monitoring. Finally, the actions of public information are presented. The recommendations of the Health and safety Committee are included in appendix

  12. National Public Information Symposium on Peaceful Uses of Nuclear Energy, NUC Info' 2000. Radioactive Waste Management and Site Restoration in Uranium Industry. Proceedings. Volume 2

    International Nuclear Information System (INIS)

    Dobos, Ion; Comsa, Olivia

    2000-01-01

    These proceedings published in two volumes contain materials presented at the National Public Information Symposium on Peaceful Uses of Nuclear Energy, NUC Info' 2000. Radioactive Waste Management and Site Restoration in Uranium Industry - held on 5th September to 8th September 2000 at Baita - Bihor, Romania. The proceedings are structured in 4 sections: 1. Management of radioactive wastes arising from uranium mining, milling and decommissioning; 2. Uranium mine closing down; 3. Environmental restoration of uranium mining and milling sites; 4. Management of radioactive wastes arising from nuclear applications. The contributions in this volume debate the issues of environment restoration at uranium ore mining and management of radioactive wastes resulted from nuclear applications

  13. Information report of AREVA Tricastin site - 2015 Edition. This report is written in compliance with article L. 125-15 of the French environment code

    International Nuclear Information System (INIS)

    2016-01-01

    Published in compliance with the French code of the environment, this report presents, first, the AREVA Tricastin site with its facilities (AREVA NC, EURODIF Production, SET, SOCATRI and AREVA NP Pierrelatte) and activities in the domain of uranium conversion and enrichment. Then, it takes stock of the dispositions implemented for the limitation and prevention of risks and summarizes the events declared in 2015. Next, it presents the management of the site effluents and wastes and the environmental monitoring. Finally, the actions of public information are presented. The recommendations of the Health and safety Committee are included in appendix

  14. [Perinatal complications in patients with chronic renal insufficiency on hemodialysis].

    Science.gov (United States)

    Vázquez-Rodríguez, Juan Gustavo; del Angel-García, Guadalupe

    2010-09-01

    Pregnant patients with chronic renal insufficiency treated with hemodialysis experience adverse perinatal results. To compare perinatal complications of patients with chronic renal insufficiency undergoing hemodialysis who become pregnant vs. the complications of women with chronic renal insufficiency not undergoing dialysis but who then require dialysis during gestation. Transversal and retrospective study that included three patients with chronic renal insufficiency on chronic hemodialysis who became pregnant (group A) and three patients with chronic renal insufficiency without hemodialysis at the time of conception but who required dialysis during gestation (group B). Perinatal results were compared. Statistical analysis was performed with measures of central tendency and dispersion and Student t-test. Group A had 25 sessions vs. group B with 29 hemodialysis sessions (p = 0.88). Maternal complications were anemia 100% (six cases), Cesarean delivery 83.3% (group A 2 cases vs. group B 2 cases), preeclampsia 50% (group A 2 cases vs. group B 1 case), uncontrolled hypertension 50% (group A 2 cases vs. group B 1 case), preterm delivery 50% (group A 2 cases vs. group B 1 case), transfusion 33.3% (group A 2 cases), polyhydramnios 33.3% (group A 1 case vs. group B 1 case) and abortion 16.6% (group A 1 case). Fetal complications included fetal loss 16.6% (group A 1 case), neonatal mortality 33.3% (group A 1 cases vs. group B 1 case), prematurity 50% (group A2 cases vs. group B 1 case), fetal distress 50% (group A 1 case vs. group B 2 cases), respiratory failure 33.3% (group A 2 cases) and fetal growth restriction 16.6% (group A 1 case). Frequency of perinatal complications is elevated in both groups.

  15. Adalimumab treatment in patients with rheumatoid arthritis with renal insufficiency.

    Science.gov (United States)

    Sumida, Keiichi; Ubara, Yoshifumi; Suwabe, Tatsuya; Hayami, Noriko; Hiramatsu, Rikako; Hasegawa, Eiko; Yamanouchi, Masayuki; Hoshino, Junichi; Sawa, Naoki; Takaichi, Kenmei

    2013-03-01

    To elucidate the safety of adalimumab for rheumatoid arthritis (RA) patients with renal insufficiency, including those with end-stage renal disease undergoing hemodialysis. Sixty-five RA patients, including 2 patients undergoing hemodialysis, treated with adalimumab in our hospital from December 1, 2008 to June 30, 2011 were retrospectively analyzed. Renal function was evaluated by the estimated glomerular filtration rate (eGFR) calculated from the Cockcroft-Gault formula at the start and end of followup after adalimumab treatment. The proportion of the patients who discontinued or switched adalimumab treatment and the change of the eGFR were compared between patients with (n = 39) and without (n = 26) renal insufficiency, defined as an eGFR patients who discontinued or switched adalimumab treatment (51.3% versus 50.0%; P = 0.53). The mean ± SD changes of eGFR were from 41.6 ± 13.3 to 43.4 ± 17.9 ml/minute/1.73 m(2) in patients with renal insufficiency and from 83.6 ± 17.5 to 83.0 ± 16.8 ml/minute/1.73 m(2) in patients without renal insufficiency, and the differences in each group were not statistically significant (P = 0.92 and P = 0.78, respectively). No severe infections or other severe adverse events were observed in either group during adalimumab treatment. Our data indicate that adalimumab does not worsen renal function and has no serious adverse events even for RA patients with renal insufficiency, including those undergoing hemodialysis, and suggest that it could be a potential therapeutic option for them. Copyright © 2013 by the American College of Rheumatology.

  16. Science and Technology Undergraduate Students' Use of the Internet, Cell Phones and Social Networking Sites to Access Library Information

    Science.gov (United States)

    Salisbury, Lutishoor; Laincz, Jozef; Smith, Jeremy J.

    2012-01-01

    Many academic libraries and publishers have developed mobile-optimized versions of their web sites and catalogs. Almost all database vendors and major journal publishers have provided a way to connect to their resources via the Internet and the mobile web. In light of this pervasive use of the Internet, mobile devices and social networking, this…

  17. Characterization of Fouling at Field Test Sites of the ONR Biofouling Program: Background Information and Results for 2006-2007

    Science.gov (United States)

    2008-10-01

    bishopmuseum.org/HBS/invert/list_home.htm 7) Kewalo Marine Laboratory’s database of reproductive patterns in local marine invertebrates . http...Hurlbut CJ. 1991. Community recruitment: settlement and juvenile survival of seven co- occurring species of sessile marine invertebrates . Marine ...accumulation of macrofouling to immersed objects can vary temporally depending on the site. Reproduction of macroalgae and fouling invertebrates in

  18. The insufficient part of abiogenesis theory - natural selection

    Science.gov (United States)

    Ploompuu, Tõnu

    2016-04-01

    Abiogenesis has already been studied for a whole century. There have been studies on the synthesis of precursors of biopolymers, concentration processes and polymerization pathways, sites of initiation of life. Autoreplication has been explained. Protocells have been constructed from abiogenic membranes. But one essential aspect for life - the natural selection - has been marginalized in these investigations. Despite the convincing use of natural selection in biology for one and half century, it has not been used sufficiently in the models of the beginning of life. Pictorially - Darwin's pond model is used without darwinism. This generates an unnecessary interruption on the path for understanding the process. Natural selection is essential in abiogenesis, in the genesis of biological information system. A selection of more collaborative autoreplicate biopolymers and the depolymerisation of others was required. Only natural selection was able to combine biopolymer molecules for life. The primary natural selection can operate only in an environment with variable physical and chemical conditions. The selective agent must constantly fluctuate during a long time span and a large area. Formation of the simplest complex of life needs homeostasis. The best sites for constant fluctuations are littoral areas of oceans. Two very constant fluctuations - waves and tides - occur there. The best conditions for the origin of life were exactly in the end of the Late Heavy Bombardment at temperature nealy 100° C. Earth's surface was then protected against the UV destruction by a thick cloud cover. High evaporation at the hotter parts of shore rocks increased the concentration of the primordial soup and there was excellent selective power by routine water level fluctuations. Because of the water level fluctuations salty ocean water and fresh water from continuous downpours alternated at the littoral zones. In low temperatures the formation of life would be hindered by UV

  19. Information

    International Nuclear Information System (INIS)

    Boyard, Pierre.

    1981-01-01

    The fear for nuclear energy and more particularly for radioactive wastes is analyzed in the sociological context. Everybody agree on the information need, information is available but there is a problem for their diffusion. Reactions of the public are analyzed and journalists, scientists and teachers have a role to play [fr

  20. Economical and technical optimization of site investigations - a multivariate approach based on Stripa F1 and F2 borehole information

    International Nuclear Information System (INIS)

    Schunnesson, H.; Lundholm, I.

    1992-01-01

    In this report multivariate analysis is presented and used as a tool to optimize site investigations. The technique is tested on earlier accumulated data from bore hole F1 and F2 in the Stripa mine, in an attempt to predict the hydraulic conductivity of the rock. Different investigation methods can be selected only on behalf of their correlation to the hydraulic conductivity and accurate predictions can be made with as high resolution as the core mapping data and the data from the geophysical logging allows. In the second part of the report the integration of this technique in the pre-investigation is discussed. The most important steps is to form a site analysis group, responsible for data collection, analysis and investigation, utilize all at the time available data to improve the investigation. This will also lead to a less rigid and more flexible pre-investigation that will improve the quality and reduce time consumption. (12 refs.)(au)

  1. [Medical information systems in the internet : current data about the dermatologic web site www.dermis.net].

    Science.gov (United States)

    Diepgen, T L; Tanko, Z; Weisshaar, E; Matvijets, A; Simon, M

    2009-12-01

    www.dermis.net was established in 1994 as a dermatological information system with now more than 4,000 pages and over 7,500 dermatological images in an atlas. 1,200 dermatological diagnoses and medical information with 1,100 synonyms can be searched by body location and in alphabetical order. Additionally, there are seven information modules about skin cancer, atopic dermatitis, rosacea, skin care, eczema, fungal diseases and hemorrhoids with links to other medical pages like Cochrane Library. Pediatric skin diseases are covered in PeDOIA. www.dermis.net is meanwhile available in German, English, Spanish, Portuguese, French and Turkish language. Current contents of this information system and user behavior are presented in this paper.

  2. A toolbox for the fast information analysis of multiple-site LFP, EEG and spike train recordings

    Directory of Open Access Journals (Sweden)

    Logothetis Nikos K

    2009-07-01

    Full Text Available Abstract Background Information theory is an increasingly popular framework for studying how the brain encodes sensory information. Despite its widespread use for the analysis of spike trains of single neurons and of small neural populations, its application to the analysis of other types of neurophysiological signals (EEGs, LFPs, BOLD has remained relatively limited so far. This is due to the limited-sampling bias which affects calculation of information, to the complexity of the techniques to eliminate the bias, and to the lack of publicly available fast routines for the information analysis of multi-dimensional responses. Results Here we introduce a new C- and Matlab-based information theoretic toolbox, specifically developed for neuroscience data. This toolbox implements a novel computationally-optimized algorithm for estimating many of the main information theoretic quantities and bias correction techniques used in neuroscience applications. We illustrate and test the toolbox in several ways. First, we verify that these algorithms provide accurate and unbiased estimates of the information carried by analog brain signals (i.e. LFPs, EEGs, or BOLD even when using limited amounts of experimental data. This test is important since existing algorithms were so far tested primarily on spike trains. Second, we apply the toolbox to the analysis of EEGs recorded from a subject watching natural movies, and we characterize the electrodes locations, frequencies and signal features carrying the most visual information. Third, we explain how the toolbox can be used to break down the information carried by different features of the neural signal into distinct components reflecting different ways in which correlations between parts of the neural signal contribute to coding. We illustrate this breakdown by analyzing LFPs recorded from primary visual cortex during presentation of naturalistic movies. Conclusion The new toolbox presented here implements fast

  3. A toolbox for the fast information analysis of multiple-site LFP, EEG and spike train recordings.

    Science.gov (United States)

    Magri, Cesare; Whittingstall, Kevin; Singh, Vanessa; Logothetis, Nikos K; Panzeri, Stefano

    2009-07-16

    Information theory is an increasingly popular framework for studying how the brain encodes sensory information. Despite its widespread use for the analysis of spike trains of single neurons and of small neural populations, its application to the analysis of other types of neurophysiological signals (EEGs, LFPs, BOLD) has remained relatively limited so far. This is due to the limited-sampling bias which affects calculation of information, to the complexity of the techniques to eliminate the bias, and to the lack of publicly available fast routines for the information analysis of multi-dimensional responses. Here we introduce a new C- and Matlab-based information theoretic toolbox, specifically developed for neuroscience data. This toolbox implements a novel computationally-optimized algorithm for estimating many of the main information theoretic quantities and bias correction techniques used in neuroscience applications. We illustrate and test the toolbox in several ways. First, we verify that these algorithms provide accurate and unbiased estimates of the information carried by analog brain signals (i.e. LFPs, EEGs, or BOLD) even when using limited amounts of experimental data. This test is important since existing algorithms were so far tested primarily on spike trains. Second, we apply the toolbox to the analysis of EEGs recorded from a subject watching natural movies, and we characterize the electrodes locations, frequencies and signal features carrying the most visual information. Third, we explain how the toolbox can be used to break down the information carried by different features of the neural signal into distinct components reflecting different ways in which correlations between parts of the neural signal contribute to coding. We illustrate this breakdown by analyzing LFPs recorded from primary visual cortex during presentation of naturalistic movies. The new toolbox presented here implements fast and data-robust computations of the most relevant

  4. Hanford Site Air Operating Permit Application Supplemental Information [Sec 1 Thru 5] Vol 1 Thru 3 Appendices A Thru C

    Energy Technology Data Exchange (ETDEWEB)

    CURN, B.L.

    2000-05-01

    This report documents radionuclide air emissions from the Hanford Site in 1998 and the resulting effective dose equivalent to the maximally exposed individual (MEI) member of the public. The report has been prepared in accordance with the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (40 CFR 61), Subpart H: ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities,'' and with the Washington Administrative Code Chapter 246247, Radiation Protection - Air Emissions. The federal regulations in 40 CFR 61, Subpart H, require the measurement and reporting of radionuclides emitted from Department of Energy facilities and the resulting offsite dose from those emissions. A standard of 10 mrem/yr effective dose equivalent (EDE) is imposed on them. The EDE to the MEI due to routine emissions in 1998 from Hanford Site point sources was 1.3 E-02 mrem (1.3 E-04 mSv). which is 0.13 percent of the federal standard. Chapter 246-247 of the Washington Administrative Code (WAC) requires the reporting of radionuclide emissions from all Department of Energy Hanford Site sources. The state has adopted into these regulations the 40 CFR 61 standard of 10 mrem/yr EDE. The EDE to the MEI attributable to diffuse and fugitive radionuclide air emissions from the Hanford Site in 1998 was 2.5 E-02 mrem (2.S E-04 mSv). This dose added to the dose from point sources gives a total for all sources of 3.8 E-02 mrem/yr (3.8 E-04 mSv) EDE. which is 0.38 percent of the 10 mrem/yr standard. An unplanned release on August 26, 1998, in the 300 Area of the Hanford Site resulted in a potential dose of 4.1 E-02 mrem to a hypothetical individual at the nearest point of public access to that area. This hypothetical individual was not the MEI since the wind direction on the day of the release was away from the MEI residence. The potential dose from

  5. News about the genetics of congenital primary adrenal insufficiency.

    Science.gov (United States)

    Roucher-Boulez, Florence; Mallet-Motak, Delphine; Tardy-Guidollet, Véronique; Menassa, Rita; Goursaud, Claire; Plotton, Ingrid; Morel, Yves

    2018-04-13

    Primary adrenal insufficiency (PAI) is characterized by impaired production of steroid hormones due to an adrenal cortex defect. This condition incurs a risk of acute insufficiency which may be life-threatening. Today, 80% of pediatric forms of PAI have a genetic origin but 5% have no clear genetic support. Recently discovered mutations in genes relating to oxidative stress have opened the way to research on genes unrelated to the adrenal gland. Identification of causal mutations in a gene responsible for PAI allows genetic counseling, guidance of follow-up and prevention of complications. This is particularly true for stress oxidative anomalies, as extra-adrenal manifestations may occur due to the sensitivity to oxidative stress of other organs such as the heart, thyroid, liver, kidney and pancreas. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  6. Relative adrenal insufficiency in post-transplant lymphoproliferative disorder.

    Directory of Open Access Journals (Sweden)

    Cinclair R

    2003-01-01

    Full Text Available Post-transplant lymphoproliferative disorder is treated with rapid decrement of immunosuppressive therapy. This cannot be achieved with ease in patients on long-term glucocorticoid therapy, as chronically suppressed adrenal glands may not be capable of mounting adequate response to stress. A 52-year-old Caucasian male presented with fever, orthostatic hypotension, lymphadenopathy and hyponatraemia. Serum cortisol levels were within normal levels with a sub optimal response to stimulation by ACTH. Hyponatraemia and orthostasis responded poorly to fluid restriction, saline and salt repletion but corrected after increasing the steroid dose. The normal baseline cortisol levels represented a stimulated adrenal gland, however, the ACTH stimulation had inadequate response. This sub optimal stimulation and a good response to increased steroids suggest the presence of relative or occult adrenal insufficiency. Relative adrenal insufficiency must be considered in patients who have received prolonged glucocorticoid therapy and have symptoms such as hypotension and/or hyponatraemia.

  7. Rectal hydrocortisone during vomiting in children with adrenal insufficiency.

    Science.gov (United States)

    Ní Chróinín, M; Fallon, M; Kenny, D; Moriarty, S; Hoey, H; Costigan, C

    2003-01-01

    To evaluate rectal hydrocortisone as an emergency glucocorticoid replacement therapy in adrenal insufficient children. A parental questionnaire evaluated preferred treatment, problems or benefits of i.m. and rectal hydrocortisone, frequency and indications for administration and who administered treatment. Admissions of children with adrenal insufficiency were monitored. There were 39/52 families who responded to the questionnaire. 93% (26/28) preferred rectal hydrocortisone. Parents or children who previously received emergency treatment from a doctor now self-administered rectal hydrocortisone. The cost of suppositories and i.m. hydrocortisone is similar; however, storage of suppositories was inconvenient. One girl presented with pneumonia and collapse despite rectal hydrocortisone and a hydrocortisone level at admission of >2000 nmol/l with normal electrolytes. Rectal hydrocortisone is an acceptable and safe emergency therapy. We still advise i.m. hydrocortisone if rectal administration is not possible or with suppository extrusion.

  8. Diabetes mellitus and exocrine pancreatic insufficiency (review of literature

    Directory of Open Access Journals (Sweden)

    L.T. Daminova

    2018-02-01

    Full Text Available Currently, an increasing importance is given to the study of the problem of exocrine pancreatic insufficiency, which is observed in a significant number of patients with diabetes mellitus (DM type 1 and 2 and can potentially affect the compensation of DM. The mechanism of reducing the external secretion of the pancreas in DM is associated with an imbalance of inhibitory and stimulating pancreatic secretion of hormones, with fibrosis of the gland as a result of diabetic angiopathy. In type 2 DM, the mechanisms that result from the metabolic syndrome are involved in the pathogenesis of exocrine pancreatic insufficiency. Enzyme replacement the­rapy should be considered as one of the promising methods of treating DM patients.

  9. [An update on the treatment of venous insufficiency in pregnancy].

    Science.gov (United States)

    Rodríguez-Nora, B; Álvarez-Silvares, E

    Chronic venous insufficiency is a long-term pathological condition resulting from anatomical or functional alterations of the venous system. This leads to the appearance of symptoms and physical signs that affect a large part of the population and particularly pregnant women, due to the physiology of pregnancy. The few published studies on the use of pharmacological treatments of venous insufficiency in this group of the population, often makes the management of this condition difficult in routine clinical practice. A review is presented in this article, with all the latest updates in the treatment of this condition during pregnancy. There are numerous general, and some pharmacological, recommendations, that we can safely offer the pregnant patient. Copyright © 2017 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Adrenal insufficiency in a child with MELAS syndrome.

    Science.gov (United States)

    Afroze, Bushra; Amjad, Nida; Ibrahim, Shahnaz H; Humayun, Khadija Nuzhat; Yakob, Yusnita

    2014-11-01

    Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) are established subgroups of mitochondrial encephalomyopathy. m.3243A>G a common point mutation is detected in tRNA in majority of patients with MELAS phenotype whereas m.8344A>G point mutation in tRNA is observed, in MERRF phenotype. Adrenal insufficiency has not been reported in mitochondrial disease, except in Kearns-Sayre Syndrome (KSS), which is a mitochondrial deletion syndrome. We report an unusual presentation in a five year old boy who presented with clinical phenotype of MELAS and was found to have m.8344A>G mutation in tRNA. Addison disease was identified due to hyperpigmentation of lips and gums present from early childhood. This is the first report describing adrenal insufficiency in a child with MELAS phenotype. Copyright © 2014 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  11. Cytogenetic Analysis of 65 Women with Premature Ovarian Insufficiency

    OpenAIRE

    Seda Ates

    2016-01-01

    Aim: Premature ovarian insufficiency (POI) is characterized as amenorrhea for more than 6 months, occurring before the age of 40, with an increased follicle-stimulating hormone and low estrogen concentrations. The aim of our study is to determine the types and distribution of cytogenetic abnormalities among women with POI. Material and Method: The study is based on the retrospective karyotype analysis of 65 women with idiopathic POI referred to the Medical Genetics Department at the Bezmialem...

  12. The Soft Palate Friendly Speech Bulb for Velopharyngeal Insufficiency

    OpenAIRE

    Kahlon, Sukhdeep Singh; Kahlon, Monaliza; Gupta, Shilpa; Dhingra, Parvinder Singh

    2016-01-01

    Velopharyngeal insufficiency is an anatomic defect of the soft palate making palatopharyngeal sphincter incomplete. It is an important concern to address in patients with bilateral cleft lip and palate. Speech aid prosthesis or speech bulbs are best choice in cases where surgically repaired soft palate is too short to contact pharyngeal walls during function but these prosthesis have been associated with inadequate marginal closure, ulcerations and patient discomfort. Here is a case report of...

  13. Repair of traumatic tricuspid insufficiency via minimally invasive port access.

    Science.gov (United States)

    Kasahara, Hirofumi; Kudo, Mikihiko; Kawajiri, Hiroyuki; Yozu, Ryohei

    2010-04-01

    We report on a successful tricuspid valve plasty using port-access minimally invasive cardiac surgery (MICS) for severe traumatic tricuspid insufficiency caused by blunt chest trauma suffered 15 years previously. A combination repair procedure, consisting of cleft closures, plication of the anteroseptal commissure, and ring annuloplasty, was necessary to achieve valve competence and proved possible via port access without difficulty. Port-access MICS is an alternative approach for tricuspid valve surgery.

  14. Relationship between clinical signs and symptoms of convergence insufficiency.

    Science.gov (United States)

    Bade, Annette; Boas, Mark; Gallaway, Michael; Mitchell, G Lynn; Scheiman, Mitchell; Kulp, Marjean T; Cotter, Susan A; Rouse, Michael

    2013-09-01

    The percentage of children who are symptomatic has been shown to increase with the number of signs of convergence insufficiency (CI). Our goal was to investigate whether there is a relationship between the severity of the clinical signs of CI and symptom level reported in children with a three-sign symptomatic CI. The Convergence Insufficiency Treatment Trial enrolled 221 children with symptomatic CI from ages 9 to 17 years. Inclusion criteria included the following three signs of CI: (1) exophoria at near at least 4Δ greater than at distance, (2) insufficient positive fusional vergence (PFV) at near, and (3) a receded near point of convergence (NPC) of 6 cm break or greater. The relationships between the severity of each sign of CI (mild, moderate, and severe) and the level of symptoms as measured by the Convergence Insufficiency Symptom Survey (CISS) at baseline were evaluated. Mean CISS scores were not significantly different between mild, moderate, and severe exophoria (p = 0.60), PFV blur (p = 0.99), Sheard's criterion (p = 0.89), or NPC break (p = 0.84). There was also no difference between the frequency of subjects scoring at mild, moderate, or severe levels on the CISS and the severity of each sign of CI. Correlations between individual clinical signs and the CISS score were very low and not statistically significant. Among symptomatic children with a CISS score of 16 or higher and three clinical signs of CI, there is no further association between the severity of the clinical signs and their level of symptoms.

  15. Vitamin D deficiency and insufficiency among patients with prostate cancer.

    Science.gov (United States)

    Trump, Donald L; Chadha, Manpreet K; Sunga, Annette Y; Fakih, Marwan G; Ashraf, Umeer; Silliman, Carrie G; Hollis, Bruce W; Nesline, Mary K; Tian, Lili; Tan, Wei; Johnson, Candace S

    2009-10-01

    To assess the frequency of vitamin D deficiency among men with prostate cancer, as considerable epidemiological, in vitro, in vivo and clinical data support an association between vitamin D deficiency and prostate cancer outcome. The study included 120 ambulatory men with recurrent prostate cancer and 50 with clinically localized prostate cancer who were evaluated and serum samples assayed for 25-OH vitamin D levels. Then 100 controls (both sexes), matched for age and season of serum sample, were chosen from a prospective serum banking protocol. The relationship between age, body mass index, disease stage, Eastern Cooperative Oncology Group performance status, season and previous therapy on vitamin D status were evaluated using univariate and multivariate analyses. The mean 25-OH vitamin D level was 25.9 ng/mL in those with recurrent disease, 27.5 ng/mL in men with clinically localized prostate cancer and 24.5 ng/mL in controls. The frequency of vitamin D deficiency (<20 ng/mL) and insufficiency (20-31 ng/mL) was 40% and 32% in men with recurrent prostate; 28% had vitamin D levels that were normal (32-100 ng/mL). Among men with localized prostate cancer, 18% were deficient, 50% were insufficient and 32% were normal. Among controls, 31% were deficient, 40% were insufficient and 29% were normal. Metastatic disease (P = 0.005) and season of blood sampling (winter/spring; P = 0.01) were associated with vitamin D deficiency in patients with prostate cancer, while age, race, performance status and body mass index were not. Vitamin D deficiency and insufficiency were common among men with prostate cancer and apparently normal controls in the western New York region.

  16. Effective antihypertensive treatment postpones renal insufficiency in diabetic nephropathy

    DEFF Research Database (Denmark)

    Parving, H H; Smidt, U M; Hommel, E

    1993-01-01

    The effect of long-term, aggressive, antihypertensive treatment on kidney function in diabetic nephropathy was studied prospectively in 11 insulin-dependent diabetic patients (mean age, 30 years). Renal function was assessed every 4 months by measurement of glomerular filtration rate (GFR) (single...... infarction (GFR, 46 mL/min/1.73 m2). Effective antihypertensive treatment postpones renal insufficiency in diabetic nephropathy....

  17. Obstructed pancreaticojejunostomy partly explains exocrine insufficiency after pancreatic head resection.

    Science.gov (United States)

    Nordback, Isto; Parviainen, Mickael; Piironen, Anneli; Räty, Sari; Sand, Juhani

    2007-02-01

    The majority of patients with long-term survival after pancreatic head resection suffer from pancreatic exocrine insufficiency. The objective of this study was to investigate whether this is due to glandular malfunction or obstructed pancreaticojejunal anastomosis. Twenty-six patients (10 M, 16 F, mean age 61 years, range 34-81 years) were re-examined a median of 52 months (range 3-76 months) after pancreatic head resection and end-to-end invaginated pancreaticojejunostomy. Pancreatic exocrine function was measured by fecal elastase-1 assay. The size of the pancreatic remnant, glandular secretion and the flow through the anastomosis were analyzed with secretin-stimulated dynamic magnetic resonance pancreatography (D-MRP). All patients had pancreatic exocrine insufficiency, 24 (92%) of them having severe insufficiency. Eighteen patients (69%) reported moderate to severe diarrhea. Lowest fecal elastase-1 concentrations were associated with the initial diagnosis of chronic pancreatitis or ductal adenocarcinoma, suggesting preoperative primary or secondary chronic pancreatitis as important determinants. The size of the remnant gland did not correlate with the fecal elastase-1 concentrations. D-MRP failed in three patients. Severe glandular malfunctions were found in 7 (30%) of the 23 successful D-MRP examinations. The anastomosis was totally obstructed in 5 patients (22%) or partially obstructed in 6 (26%) but remained perfectly open in 5 patients (22%). The five patients with perfect anastomoses had the highest measured median fecal elastase-1 activity. Although late diarrhea and pancreatic exocrine insufficiency may be partly induced already by the disease treated with resection, at least half may be explained by obstructed anastomosis. To obtain better late functional results, improvements may be required in the surgical techniques.

  18. The importance of geological data and derived information in seismic response assessment for urban sites. An example from the Island of Crete, Greece

    Science.gov (United States)

    Tsangaratos, Paraskevas; Loupasakis, Constantinos; Rozos, Dimitrios; Rondoyianni, Theodora; Vafidis, Antonios; Savvaidis, Alexandros; Soupios, Pantelis; Papadopoulos, Nikos; Sarris, Apostolos

    2015-04-01

    The magnitude, frequency content and duration of an earthquake ground motion depends mainly on the surrounding geological, tectonic and geomorphological conditions. Numerous reports have been contacted illustrating the necessity of providing accurate geological information in order to estimate the level of seismic hazard. In this context, geological information is the outcome of processing primary, raw field data and geotechnical investigation data that are non - organized and associated with the geological model of the study area. In most cases, the geological information is provided as an advance element, a key component of the "function" that solves any geo-environmental problem and is primarily reflected on analogue or digital maps. The main objective of the present study is to illustrate the importance of accurate geological information in the thirteen (13) selected sites of the Hellenic Accelerometric Network (HAN) in the area of Crete Island, in order to estimate the seismic action according to Eurocode (EC8). As an example the detailed geological-geotechnical map of the area around HAN site in Rethymno city, Crete is presented. The research area covers a 250m radius surrounding the RTHE HAN-station at a scale of 1: 2000 with detail description of the geological and geotechnical characteristics of the formations as well as the tectonic features (cracks, upthrust, thrust, etc) of the rock mass. The field survey showed that the RTHE station is founded over limestones and dolomites formations. The formations exhibit very good geomechanical behaviour; however they present extensive fragmentation and karstification. At this particular site the identification of a fault nearby the station proved to be significant information for the geophysical research as the location and orientation of the tectonic setting provided new perspective on the models of seismic wave prorogation. So, the geological data and the induced information along with the tectonic structure of

  19. Central Adrenal Insufficiency and Diabetes Insipidus Misdiagnosed as Severe Depression

    Directory of Open Access Journals (Sweden)

    Naoki Hiroi

    2010-01-01

    Full Text Available A 68 year-old Japanese man, who had been suffering from immobilization and disuse syndrome, was admitted to our hospital for evaluation of polyuria with polyposia, hyponatremia and low blood pressure. His plasma osmolality was greater than that of his urine. His endocrinological examination revealed low levels of plasma adrenocorticotropic hormone (ACTH and cortisol, and a normal response of ACTH to the corticotrophin-releasing hormone (CRH challenge. Plasma ACTH did not increase with insulin loading. A low plasma vasopressin (AVP level and no response of AVP to a 5% saline administration were observed. We diagnosed central adrenal insufficiency with central diabetes insipidus. Six months after starting administration of hydrocortisone and 1-deamino-8D-arginine vasopressin, his psychological symptoms had improved, and 1.5 years after starting treatment, he was able to walk. In conclusion, it is not particularly rare for adrenal insufficiency to be misdiagnosed as depression. However, a correct early diagnosis is necessary, because, if adrenal insufficiency is not definitively diagnosed, the patient's quality of life diminishes markedly.

  20. Hereditary myopathies with early respiratory insufficiency in adults.

    Science.gov (United States)

    Naddaf, Elie; Milone, Margherita

    2017-11-01

    Hereditary myopathies with early respiratory insufficiency as a predominant feature of the clinical phenotype are uncommon and underestimated in adults. We reviewed the clinical and laboratory data of patients with hereditary myopathies who demonstrated early respiratory insufficiency before the need for ambulatory assistance. Only patients with disease-causing mutations or a specific histopathological diagnosis were included. Patients with cardiomyopathy were excluded. We identified 22 patients; half had isolated respiratory symptoms at onset. The diagnosis of the myopathy was often delayed, resulting in delayed ventilatory support. The most common myopathies were adult-onset Pompe disease, myofibrillar myopathy, multi-minicore disease, and myotonic dystrophy type 1. Single cases of laminopathy, MELAS (mitochondrial encephalomyopathy with lactic acidosis and strokelike events), centronuclear myopathy, and cytoplasmic body myopathy were identified. We highlighted the most common hereditary myopathies associated with early respiratory insufficiency as the predominant clinical feature, and underscored the importance of a timely diagnosis for patient care. Muscle Nerve 56: 881-886, 2017. © 2017 Wiley Periodicals, Inc.

  1. Impact of placental insufficiency on fetal skeletal muscle growth

    Science.gov (United States)

    Hay, William W.

    2016-01-01

    Intrauterine growth restriction (IUGR) caused by placental insufficiency is one of the most common and complex problems in perinatology, with no known cure. In pregnancies affected by placental insufficiency, a poorly functioning placenta restricts nutrient supply to the fetus and prevents normal fetal growth. Among other significant deficits in organ development, the IUGR fetus characteristically has less lean body and skeletal muscle mass than their appropriately-grown counterparts. Reduced skeletal muscle growth is not fully compensated after birth, as individuals who were born small for gestational age (SGA) from IUGR have persistent reductions in muscle mass and strength into adulthood. The consequences of restricted muscle growth and accelerated postnatal “catch-up” growth in the form of adiposity may contribute to the increased later life risk for visceral adiposity, peripheral insulin resistance, diabetes, and cardiovascular disease in individuals who were formerly IUGR. This review will discuss how an insufficient placenta results in impaired fetal skeletal muscle growth and how lifelong reductions in muscle mass might contribute to increased metabolic disease risk in this vulnerable population. PMID:26994511

  2. Respiratory insufficiency with preserved diaphragmatic function in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Yamauchi, Rika; Imai, Tomihiro; Tsuda, Emiko; Hozuki, Takayoshi; Yamamoto, Daisuke; Shimohama, Shun

    2014-01-01

    We performed a longitudinal study to elucidate the correlation between respiratory insufficiency and respiratory biomarkers, including diaphragmatic compound muscle action potential (DCMAP), at the initiation of noninvasive ventilation (NIV) in patients with amyotrophic lateral sclerosis (ALS). The patients were assessed at least every six months. Additional assessments were performed at the start of respiratory therapy when the patients met the criteria for the initiation of NIV. Each assessment consisted of a full neurological examination, a phrenic nerve conduction study, respiratory function tests, and nocturnal pulsed oximetry. We enrolled 43 patients with either definite or probable ALS as defined by the revised El Escorial criteria. The patients were divided into two groups according to the timing of the initiation of respiratory therapy. Seventeen patients (group A) met the criteria for NIV initiation when their DCMAP remained normal. Twenty-six patients (group B) met the criteria when their DCMAP decreased below normal limits. Although respiratory function parameters were significantly worse in group B compared with group A at NIV initiation, more than 80% of the patients in both groups developed nocturnal desaturation during sleep. DCMAP is not always a reliable indicator for determining the optimal timing for NIV initiation during the progression of respiratory insufficiency in ALS. Physicians should be aware of the risk of respiratory insufficiency during sleep in patients with ALS.

  3. Leptomeningeal dissemination of an astrocytoma causing hypophyseal insufficiency

    International Nuclear Information System (INIS)

    Suzan, S.; Cigdem, O.; Furkan, U.; Baki, A.

    2012-01-01

    Full text: Introduction: Hypophyseal insufficiency is an unusual clinical presentation of metastatic disease. Objectives: In this report, a case of leptomeningeal metastasis of an astrocytoma to the infundibular recess, causing hypophyseal insufficiency is presented with its magnetic resonance imaging (MRI) findings. Materials and methods: A 27-year-old woman presented with nausea, vomiting and generalized weakness. Her laboratory results were consistent with hypopituitarism. She had an operation history for astrocytoma. She was referred to radiology department for brain MRI study. Contrast-enhanced MRI scan showed extensive wall enhancement of ventricles consistent with leptomeningeal metastases. A nodular mass with pronounced contrast enhancement was also detected at the infundibular stalk. Results: Because suprasellar cistern was normal and extensive leptomeningeal metastases was detected, the nodular mass at the infundibular stalk thought to be secondary to leptomeningeal involvement of the infundibular recess. Conclusion: When a patient with a known malignancy presented with hypophyseal insufficiency, it should be thought that leptomeningeal metastases to the infundibular recess may also be a cause. The neuroimaging, especially contrast-enhanced studies, is necessary for the confirmation

  4. Multi-criteria site selection for fire services: the interaction with analytic hierarchy process and geographic information systems

    Directory of Open Access Journals (Sweden)

    T. Erden

    2010-10-01

    Full Text Available This study combines AHP and GIS to provide decision makers with a model to ensure optimal site location(s for fire stations selected. The roles of AHP and GIS in determining optimal locations are explained, criteria for site selection are outlined, and case study results for finding the optimal fire station locations in Istanbul, Turkey are included. The city of Istanbul has about 13 million residents and is the largest and most populated city in Turkey. The rapid and constant growth of Istanbul has resulted in the increased number of fire related cases. Fire incidents tend to increase year by year in parallel with city expansion, population and hazardous material facilities. Istanbul has seen a rise in reported fire incidents from 12 769 in 1994 to 30 089 in 2009 according to the interim report of Istanbul Metropolitan Municipality Department of Fire Brigade. The average response time was approximately 7 min 3 s in 2009. The goal of this study is to propose optimal sites for new fire station creation to allow the Fire Brigade in Istanbul to reduce the average response time to 5 min or less. After determining the necessity of suggesting additional fire stations, the following steps are taken into account: six criteria are considered in this analysis. They are: High Population Density (HPD; Proximity to Main Roads (PMR; Distance from Existing Fire Stations (DEF; Distance from Hazardous Material Facilities (DHM; Wooden Building Density (WBD; and Distance from the Areas Subjected to Earthquake Risk (DER. DHM criterion, with the weight of 40%, is the most important criterion in this analysis. The remaining criteria have a weight range from 9% to 16%. Moreover, the following steps are performed: representation of criterion map layers in GIS environment; classification of raster datasets; calculating the result raster map (suitability map for potential fire stations; and offering a model that supports decision makers in selecting fire station sites

  5. Networks of High Mutual Information Define the Structural Proximity of Catalytic Sites: Implications for Catalytic Residue Identification

    DEFF Research Database (Denmark)

    Buslje, Cristina Marino; Teppa, Elin; Di Doménico, Tomas

    2010-01-01

    other non-functional conserved residues. Using a data set of 434 Pfam families included in the catalytic site atlas (CSA) database, we tested this hypothesis and demonstrated that MI can complement amino acid conservation scores to detect CR. The Kullback-Leibler (KL) conservation measurement was shown.......90, the Cls method was found to have a sensitivity of 0.816. In summary, we demonstrate that networks of residues with high MI provide a distinct signature on CR and propose that such a signature should be present in other classes of functional residues where the requirement to maintain a particular function...

  6. Dating Informed Correlations and Large Earthquake Recurrence at the Hokuri Creek Paleoseismic Site, Alpine Fault, South Island, New Zealand

    Science.gov (United States)

    Biasi, G. P.; Clark, K.; Berryman, K. R.; Cochran, U. A.; Prior, C.

    2010-12-01

    The Hokuri Creek paleoseismic site on the Alpine fault in south Westland, New Zealand has yielded a remarkable history of fault activity spanning the past ~7000 years. Evidence for earthquake occurrence and timing has been developed primarily from natural exposures created after a geologically major incision event a few hundred years ago. Prior to this event, the elevation of the spillway of Hokuri Creek into its previous drainage was controlled by NE translation of a shutter ridge during earthquakes. Each event increased the base level for sediment accumulation upstream by decimetres to perhaps a metre. Each increase in base level is associated with a period of accumulation principally of clean fine silts and rock flour. With infilling and time, the wetlands reestablish and sedimentation transitions to a slower and more organic-rich phase (Clark et al., this meeting). At least 18 such cycles have been identified at the site. Carbonaceous material is abundant in almost all layers. Much of the dating is done on macrofossils - individual beech tree leaves, reeds, and similar fragile features. Reworking is considered unlikely due to the fragility of the samples. All dates were developed by the Rafter Radiocarbon Laboratory of the National Isotope Centre at GNS. Delta 13C was measured and used to correct for fractionation. Dating earthquakes at the Hokuri Creek site presents some special challenges. Individual stratigraphic sections around the site expose different time intervals. The Main Section series provides the most complete single section, with over 5000 years of represented. Nearby auxiliary exposures cover nearly 1500 years more. Date series from individual exposures tend to be internally very consistent with stratigraphic ordering, but by virtue of their spatial separation, correlations between sections are more difficult. We find, however, that the distinctive layering and the typical 2-4 centuries between primary silt layers provides a way to cross

  7. Corrective Action Investigation Plan for Corrective Action Unit 139: Waste Disposal Sites, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    Grant Evenson

    2006-04-01

    Corrective Action Unit (CAU) 139 is located in Areas 3, 4, 6, and 9 of the Nevada Test Site, which is 65 miles northwest of Las Vegas, Nevada. Corrective Action Unit 139 is comprised of the seven corrective action sites (CASs) listed below: (1) 03-35-01, Burn Pit; (2) 04-08-02, Waste Disposal Site; (3) 04-99-01, Contaminated Surface Debris; (4) 06-19-02, Waste Disposal Site/Burn Pit; (5) 06-19-03, Waste Disposal Trenches; (6) 09-23-01, Area 9 Gravel Gertie; and (7) 09-34-01, Underground Detection Station. These sites are being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives with the exception of CASs 09-23-01 and 09-34-01. Regarding these two CASs, CAS 09-23-01 is a gravel gertie where a zero-yield test was conducted with all contamination confined to below ground within the area of the structure, and CAS 09-34-01 is an underground detection station where no contaminants are present. Additional information will be obtained by conducting a corrective action investigation (CAI) before evaluating corrective action alternatives and selecting the appropriate corrective action for the other five CASs where information is insufficient. The results of the field investigation will support a defensible evaluation of viable corrective action alternatives that will be presented in the Corrective Action Decision Document. The sites will be investigated based on the data quality objectives (DQOs) developed on January 4, 2006, by representatives of the Nevada Division of Environmental Protection; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and Bechtel Nevada. The DQO process was used to identify and define the type, amount, and quality of data needed to develop and evaluate appropriate corrective actions for CAU 139.

  8. Corrective Action Investigation Plan for Corrective Action Unit 137: Waste Disposal Sites, Nevada Test Site, Nevada, Rev. No.:0

    Energy Technology Data Exchange (ETDEWEB)

    Wickline, Alfred

    2005-12-01

    This Corrective Action Investigation Plan (CAIP) contains project-specific information including facility descriptions, environmental sample collection objectives, and criteria for conducting site investigation activities at Corrective Action Unit (CAU) 137: Waste Disposal Sites. This CAIP has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense. Corrective Action Unit 137 contains sites that are located in Areas 1, 3, 7, 9, and 12 of the Nevada Test Site (NTS), which is approximately 65 miles (mi) northwest of Las Vegas, Nevada (Figure 1-1). Corrective Action Unit 137 is comprised of the eight corrective action sites (CASs) shown on Figure 1-1 and listed below: (1) CAS 01-08-01, Waste Disposal Site; (2) CAS 03-23-01, Waste Disposal Site; (3) CAS 03-23-07, Radioactive Waste Disposal Site; (4) CAS 03-99-15, Waste Disposal Site; (5) CAS 07-23-02, Radioactive Waste Disposal Site; (6) CAS 09-23-07, Radioactive Waste Disposal Site; (7) CAS 12-08-01, Waste Disposal Site; and (8) CAS 12-23-07, Waste Disposal Site. The Corrective Action Investigation (CAI) will include field inspections, radiological surveys, geophysical surveys, sampling of environmental media, analysis of samples, and assessment of investigation results, where appropriate. Data will be obtained to support corrective action alternative evaluations and waste management decisions. The CASs in CAU 137 are being investigated because hazardous and/or radioactive constituents may be present in concentrations that could potentially pose a threat to human health and the environment. Existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives for the CASs. Additional information will be generated by conducting a CAI before evaluating and selecting

  9. Informe

    Directory of Open Access Journals (Sweden)

    Egon Lichetenberger

    1950-10-01

    Full Text Available Informe del doctor Egon Lichetenberger ante el Consejo Directivo de la Facultad, sobre el  curso de especialización en Anatomía Patológica patrocinado por la Kellogg Foundation (Departamento de Patología

  10. Meteorological, hydrological and oceanographical information and data for the site investigation program in the community of Oskarshamn

    Energy Technology Data Exchange (ETDEWEB)

    Larsson-McCann, Sonja; Karlsson, Anna; Nord, Margitta; Sjoegren, Jonas; Johansson, Lasse; Ivarsson, Mats; Kindell, Sven [Swedish Meteorological and Hydrological Inst., Norrkoeping (Sweden)

    2002-06-01

    The most frequent wind directions in Southern Sweden are west and south-west, with some local and regional deviations. This makes the East Coast climate somewhat less maritime than that on the West Coast, which also means that the differences are less pronounced between the actual coastal sites and their inland neighbourhood than is the case on the West Coast. Near-coast locations are far more exposed to strong winds than inland sites. An important feature of the actual coastal areas is that they are largely composed of forest; the large wind exposure at the coastline has very markedly decreased a few km inland. True annual precipitation (adjusted for measuring losses) is estimated to between 600 and 700 mm, with a slight tendency of increasing inland. A yearly mean temperature of 6-7 deg C makes the Simpevarp site about 1 deg C warmer than the region Oesthammar/Tierp. The South-eastern parts of Sweden have the lowest values of specific runoff, with a mean 1961-1990 of <10 l/s/km{sup 2}. Specific runoff for the Oskarshamn region is <6 l/s/km{sup 2}. For Oesthammar-Tierp it is 6-9 l/s/km{sup 2}. For lakes in both Southern and Northern Sweden the ice freeze-up is strongly related to lake depth; it appears earlier on a lake with small depth than on a lake with great depth. When it comes to ice break-up, there are no significant relationships between the characteristics of different lakes like for ice freeze-up. This is because ice break-up is mostly effected by weather, especially solar radiation. The water around Simpevarp is an area with good water exchange. The area is strongly effected by coastal processes induced by the local wind conditions and the stratification in the sea. The same situation is valid for the most of the water around Forsmark. Existing observing stations in the area around Oskarshamn have been located. In figure 0-1 all stations and their locations are shown. The stations that are not run by SMHI have not been evaluated due to difficulties in

  11. The utility of a geographic information system in facility/land use-related opportunities and constraints analysis for the Rocky Flats Environmental Technology Site

    International Nuclear Information System (INIS)

    Stewart, J.

    1994-01-01

    Facility/land use-related opportunities and constraints analysis, which is indispensable for the evaluation of potential future uses for a site, is essentially spatial in nature. Spatial analysis is best accomplished using a geographic information system (GIS), as a GIS allows the identification and reporting or mapping of complex relationships among multiple data layers such as geology, soils, vegetation, contamination, and facilities. GIS-based maps and reports are valuable tools for communicating facility/land use-related opportunities and constraints to decision makers. This paper defines the term open-quotes GIS,close quotes, provides an example of how a GIS could be used to conduct opportunities and constraints analysis at the Rocky Flats Environmental Technology Site (RFETS), and summarizes the benefits of using a GIS for this analysis. Because a GIS is often seen as a open-quotes black boxclose quotes shrouded in technical jargon, this paper attempts to describe the concepts and benefits of a GIS in language understandable to decision makers who are not GIS experts but who migth profit from the use of GIS products. The purpose of this paper is to alert DOE decision makers to a valuable source of facility/land use-related information that already exists at many sites and that should not be overlook during the analysis of future use options

  12. Application of Spatial Data Modeling and Geographical Information Systems (GIS) for Identification of Potential Siting Options for Various Electrical Generation Sources

    Energy Technology Data Exchange (ETDEWEB)

    Mays, Gary T [ORNL; Belles, Randy [ORNL; Blevins, Brandon R [ORNL; Hadley, Stanton W [ORNL; Harrison, Thomas J [ORNL; Jochem, Warren C [ORNL; Neish, Bradley S [ORNL; Omitaomu, Olufemi A [ORNL; Rose, Amy N [ORNL

    2012-05-01

    Oak Ridge National Laboratory (ORNL) initiated an internal National Electric Generation Siting Study, which is an ongoing multiphase study addressing several key questions related to our national electrical energy supply. This effort has led to the development of a tool, OR-SAGE (Oak Ridge Siting Analysis for power Generation Expansion), to support siting evaluations. The objective in developing OR-SAGE was to use industry-accepted approaches and/or develop appropriate criteria for screening sites and employ an array of Geographic Information Systems (GIS) data sources at ORNL to identify candidate areas for a power generation technology application. The initial phase of the study examined nuclear power generation. These early nuclear phase results were shared with staff from the Electric Power Research Institute (EPRI), which formed the genesis and support for an expansion of the work to several other power generation forms, including advanced coal with carbon capture and storage (CCS), solar, and compressed air energy storage (CAES). Wind generation was not included in this scope of work for EPRI. The OR-SAGE tool is essentially a dynamic visualization database. The results shown in this report represent a single static set of results using a specific set of input parameters. In this case, the GIS input parameters were optimized to support an economic study conducted by EPRI. A single set of individual results should not be construed as an ultimate energy solution, since US energy policy is very complex. However, the strength of the OR-SAGE tool is that numerous alternative scenarios can be quickly generated to provide additional insight into electrical generation or other GIS-based applications. The screening process divides the contiguous United States into 100 x 100 m (1-hectare) squares (cells), applying successive power generation-appropriate site selection and evaluation criteria (SSEC) to each cell. There are just under 700 million cells representing the

  13. INEL cold test pit demonstration of improvements in information derived from non-intrusive geophysical methods over buried waste sites

    International Nuclear Information System (INIS)

    1994-01-01

    Under Contract between US DOE Idaho National Engineering Laboratory (INEL) and the Blackhawk Geosciences Division of Coleman Research Corporation (BGD-CRC), geophysical investigations were conducted to improve the detection of buried wastes. Site characterization is a costly and time consuming process with the most costly components being drilling, sampling, and chemical analysis of samples. There is a focused effort at US DOE and other agencies to investigate methodologies that reduce costs and shorten the time between characterization and clean-up. These methodologies take the form of employing non-invasive (geophysical) and minimal invasive (e.g., cone penetrometer driving) techniques of characterization, and implementing a near real-time, rational decision-making process (Expedited Site Characterization). Over the Cold Test Pit (CTP) at INEL, data were acquired with multiple sensors on a dense grid. Over the CTP the interpretations inferred from geophysical data are compared with the known placement of various waste forms in the pit. The geophysical sensors employed were magnetics, frequency and time domain electromagnetics, and ground penetrating radar. Also, because of the high data density acquired, filtering and other data processing and imaging techniques were tested. The conclusions derived from the geophysical surveys were that pit boundaries, berms between cells within the pit, and individual objects placed in the pit were best mapped by the new Geonics EM61 time domain EM metal detector. Part of the reason for the effectiveness of the time domain metal detector is that objects buried in the pit are dominantly metallic. Also, the utility of geophysical data is significantly enhanced by dimensional and 3-dimensional imaging formats. These images will particularly assist remediation engineers in visualizing buried wastes

  14. National Public Information Symposium on Peaceful Uses of Nuclear Energy, NUC Info'2000. Radioactive Waste Management and Site Restoration in Uranium Industry. Proceedings. Volume 1

    International Nuclear Information System (INIS)

    Dobos, Ion; Comsa, Olivia

    2000-01-01

    These proceedings published in two volumes contain materials presented at the National Public Information Symposium on Peaceful Uses of Nuclear Energy, NUC Info'2000, Radioactive Waste Management and Site Restoration in Uranium Industry, held on 5. September to 8. September 2000 at Baita Bihor, Romania. As the name of Symposium indicates, this manifestation is addressed not only to specialists but rather to the public at large. The proceedings are structured in 4 sections: 1. Management of radioactive waste arising from uranium mining, milling and decommissioning; 2. Uranium mine close-down; 3. Environmental restoration of uranium mining and milling sites; 4. Management of radioactive waste arising from nuclear applications. The first volume also contains an inaugural session dedicated to nuclear power, nuclear fuel cycle and development of uranium industry in Romania. The contributions in the first volume deal with the management of radioactive waste arising from uranium mining, milling and decommissioning and uranium mine close-out

  15. Methodology for predictive modeling of environmental transport and health effects for waste sites at the Savannah River Plant: Environmental information document

    International Nuclear Information System (INIS)

    Stephensen, D.E.; King, C.M.; Looney, B.B.; Grant, M.W.

    1987-03-01

    This document provides information on the methods used to predict chemical transport and the associated health risk for various postulated closure activities at waste sites. The document was prepared as background documentation for the Department of Energy's proposed Environmental Impact Statement (EIS) on waste management activities for groundwater protection at the Savannah River Plant (SRP). The various mathematical formulations used in the environmental transport analysis, the exposure assessment, and the health risk assessment used in the analysis of all foreseeable scenarios as defined by the National Environmental Policy Act (CFR, 1986) are presented in this document. The scenarios do not necessarily represent actual environmental conditions for every SRP waste site. This document was prepared in support of the National Environmental Policy Act process, but does not by itself satisfy federal or state regulatory requirements. 29 refs., 11 figs

  16. Moderate perinatal thyroid hormone insufficiency alters visual system function in adult rats.

    Science.gov (United States)

    Boyes, William K; Degn, Laura; George, Barbara Jane; Gilbert, Mary E

    2018-04-21

    Thyroid hormone (TH) is critical for many aspects of neurodevelopment and can be disrupted by a variety of environmental contaminants. Sensory systems, including audition and vision are vulnerable to TH insufficiencies, but little data are available on visual system development at less than severe levels of TH deprivation. The goal of the current experiments was to explore dose-response relations between graded levels of TH insufficiency during development and the visual function of adult offspring. Pregnant Long Evans rats received 0 or 3 ppm (Experiment 1), or 0, 1, 2, or 3 ppm (Experiment 2) of propylthiouracil (PTU), an inhibitor of thyroid hormone synthesis, in drinking water from gestation day (GD) 6 to postnatal day (PN) 21. Treatment with PTU caused dose-related reductions of serum T4, with recovery on termination of exposure, and euthyroidism by the time of visual function testing. Tests of retinal (electroretinograms; ERGs) and visual cortex (visual evoked potentials; VEPs) function were assessed in adult offspring. Dark-adapted ERG a-waves, reflecting rod photoreceptors, were increased in amplitude by PTU. Light-adapted green flicker ERGs, reflecting M-cone photoreceptors, were reduced by PTU exposure. UV-flicker ERGs, reflecting S-cones, were not altered. Pattern-elicited VEPs were significantly reduced by 2 and 3 ppm PTU across a range of stimulus contrast values. The slope of VEP amplitude-log contrast functions was reduced by PTU, suggesting impaired visual contrast gain. Visual contrast gain primarily reflects function of visual cortex, and is responsible for adjusting sensitivity of perceptual mechanisms in response to changing visual scenes. The results indicate that moderate levels of pre-and post-natal TH insufficiency led to alterations in visual function of adult rats, including both retinal and visual cortex sites of dysfunction. Copyright © 2018. Published by Elsevier B.V.

  17. Traumatic tricuspid valve insufficiency. Experience in thirteen patients.

    Science.gov (United States)

    van Son, J A; Danielson, G K; Schaff, H V; Miller, F A

    1994-11-01

    From 1964 through June 1993, thirteen patients with traumatic tricuspid insufficiency were treated surgically; all were male, and the ages ranged from 17 to 64 years (median 39 years). The condition was associated with blunt chest trauma in all patients: motor vehicle accidents in twelve and an explosion of a tank of compressed air in one. The median duration between trauma and operation was 17 years (range 1 month to 37 years). Preoperatively, six patients were in sinus rhythm and seven were in atrial fibrillation. At operation, the right ventricular function appeared moderately to severely depressed in twelve patients. In twelve patients, the anterior leaflet was flail because of chordal rupture (n = 9), rupture of anterior papillary muscle (n = 3), or tear in the anterior leaflet (n = 1). In one patient, the septal leaflet was missing and in another it was retracted and adherent to the ventricular septum. In five patients the tricuspid valve was repaired and in eight it was replaced. In seven patients in the latter group, the chordae, papillary muscles, and/or tricuspid valve leaflet(s) were found to be in a contracted and atrophic state, precluding repair. No early or late deaths occurred. At follow-up extending to 26 years (median 12 years), 12 patients are in New York Heart Association class I and one patient is in class II. Nine patients were in sinus rhythm and four were in atrial fibrillation. Although our experience indicates that good functional results can still be achieved many years after the onset of traumatic tricuspid valve insufficiency, earlier diagnosis and surgical treatment should increase the feasibility of tricuspid valve insufficiency, earlier diagnosis and surgical treatment should increase the feasibility of tricuspid valve repair, prevent progressive deterioration of right ventricular function, and increase the possibility of maintaining late sinus rhythm in a greater number of patients.

  18. Gastroenterological surgery for patients with chronic respiratory insufficiency.

    Science.gov (United States)

    Shimada, M; Kano, T; Matsuzaki, Y; Miyazaki, N; Ninomiya, K

    1998-01-01

    The aim of this study was to clarify the surgical indications for patients with chronic respiratory insufficiency. Fourteen patients with chronic respiratory insufficiency who underwent abdominal surgical procedures, were retrospectively studied. The surgical indications were carefully determined based primarily on the performance status (PS) of each patient and cardiopulmonary function tests. A PS of equal to or less than 3, which meant the patient's status required bed rest > 50% of the time, and the need for assistance in performing normal activities were all factors considered for surgical indications. During the period studied, two patients were excluded from the surgical indications due to the fact that one was at a terminal stage of pulmonary disease and was completely bedridden (PS = 4), while the other demonstrated active pneumonia with a considerable amount of purulent sputa. Regarding the pulmonary function tests for patients who underwent surgery, the lowest limits of those examinations were as follows: 810 ml of vital capacity (VC), 23.8% of predicted VC, 610 ml of forced expiratory volume in one second (FEV1.0), 38.6% of predicted FEV1.0, 50.5 mmHg of PaO2 while inhaling 4 liters of oxygen and 73.8 mmHg of PaCO2. No surgery related mortality or hospital death within 30 days after operation was observed. Only two patients had cardiopulmonary complications (consisting of pulmonary edema with atrial fibrillation in one patient, and acute myocardial infarction in another patient). However, neither pneumonia, prolonged ventilatory support for more than 2 days, nor the need for a tracheostomy after surgery was observed. Gastroenterological surgery is thus considered to be indicated even for patients with chronic respiratory insufficiency, as long as the PS can be maintained (PS of equal to or less than 3) and no active pneumonia with a considerable amount of purulent sputa is present.

  19. The efficacy of supplemental intraosseous anesthesia after insufficient mandibular block

    Directory of Open Access Journals (Sweden)

    Samir Prohić

    2005-02-01

    Full Text Available It is a well-known scientific fact that only a small percentage of infiltration of inferior alveolar nerve is clinically proven to be efficient. The objective of this study was to determine the anesthetic efficacy of supplemental intraosseous injection, used after the insufficient classical mandibular block that didn't provide deep pulp anesthesia of mandibular molar planed for extraction. The experimental teeth consisted of 98 mandibular molars with clinical indication for extraction. Based on the history of disease, we indicated the extraction of the tooth. After that each tooth was tested with a electric pulp tester P1. We tested the pulp vitality and precisely determined the level of vitality. After that, each patient received classical mandibular block, and the pulp vitality was tested again. If the pulp tester indicated negative vitality for the certain mandibular molar, and the patient didn't complain about pain or discomfort during the extraction, the molar was extracted and the result was added to anesthetic success rate for the classical mandibular block. If, five minutes after receiving the mandibular block, the pulp tester indicated positive vitality (parameters of vitality or the patient complained about pain or discomfort (parameters of pain and discomfort, we used the Stabident intraosseous anesthesia system. Three minutes after the application of supplemental intraosseous injection the molar was tested with the pulp tester again. The anesthetic solution used in both anesthetic techniques is lidocaine with 1:100.000 epinephrine. The results of this study indicate that the anesthetic efficacy of the mandibular block is 74.5%, and that supplemental intraosseous anesthesia, applied after the insufficient mandibular block, provides pulpal anesthesia in 94.9% of mandibular molars. The difference between anesthetic efficacy of the classical mandibular block and anesthetic efficacy of the supplemental intraosseous anesthesia, applied

  20. The efficacy of supplemental intraosseous anesthesia after insufficient mandibular block.

    Science.gov (United States)

    Prohić, Samir; Sulejmanagić, Halid; Secić, Sadeta

    2005-02-01

    It is a well-known scientific fact that only a small percentage of infiltration of inferior alveolar nerve is clinically proven to be efficient. The objective of this study was to determine the anesthetic efficacy of supplemental intraosseous injection, used after the insufficient classical mandibular block that didn't provide deep pulp anesthesia of mandibular molar planed for extraction. The experimental teeth consisted of 98 mandibular molars with clinical indication for extraction. Based on the history of disease, we indicated the extraction of the tooth. After that each tooth was tested with a electric pulp tester P1. We tested the pulp vitality and precisely determined the level of vitality. After that, each patient received classical mandibular block, and the pulp vitality was tested again. If the pulp tester indicated negative vitality for the certain mandibular molar, and the patient didn't complain about pain or discomfort during the extraction, the molar was extracted and the result was added to anesthetic success rate for the classical mandibular block. If, five minutes after receiving the mandibular block, the pulp tester indicated positive vitality (parameters of vitality) or the patient complained about pain or discomfort (parameters of pain and discomfort), we used the Stabident intraosseous anesthesia system. Three minutes after the application of supplemental intraosseous injection the molar was tested with the pulp tester again. The anesthetic solution used in both anesthetic techniques is lidocaine with 1:100.000 epinephrine. The results of this study indicate that the anesthetic efficacy of the mandibular block is 74.5%, and that supplemental intraosseous anesthesia, applied after the insufficient mandibular block, provides pulpal anesthesia in 94.9% of mandibular molars. The difference between anesthetic efficacy of the classical mandibular block and anesthetic efficacy of the supplemental intraosseous anesthesia, applied after the

  1. Cervical spondylosis: a rare and curable cause of vertebrobasilar insufficiency.

    Science.gov (United States)

    Denis, Daniel J; Shedid, Daniel; Shehadeh, Mohammad; Weil, Alexander G; Lanthier, Sylvain

    2014-05-01

    Spondylotic vertebral artery (VA) compression is a rare cause of vertebrobasilar insufficiency and stroke. A 53-year-old man experienced multiple brief vertebrobasilar transient ischemic attacks (TIAs) and strokes, not apparently triggered by neck movements. Brain magnetic resonance imaging (MRI) documented consecutive infarcts, first in the left then right medial posterior inferior cerebellar artery (PICA) territories. Angiography showed two extracranial right vertebral artery (VA) stenoses, left VA hypoplasia, absence of left PICA and a dominant right PICA. Computed tomography angiography revealed right VA compression by osteophytes at C5-C6 and C6-C7 levels. No further vertebrobasilar insufficiency symptoms occurred in the 65 months following VA surgical decompression. Our literature review found 49 published surgical cases with vertebrobasilar symptoms caused by cervical spondylosis. Forty cases had one or more brief TIAs frequently triggered by neck movements. Three cases presented with stroke without prior TIA, with symptoms suggesting a top of the basilar artery embolic infarcts (one combined with a PICA infarct). Six cases had both TIAs and minor stroke. VA compression by uncovertebral osteophytes at the C5-C6 level was common. Dynamic angiography done in 38 cases systematically revealed worsening of VA stenosis or complete occlusion with either neck extension or rotation (ipsilateral when specified). Contralateral VA incompetence was found in 14 patients. Spondylotic VA stenosis can cause hemodynamic TIAs and watershed strokes, especially when contralateral VA insufficiency is combined to specific neck movements. Low-amplitude neck movement may suffice in severe cases. Embolic vertebrobasilar events are less frequent. VA decompression from spondylosis may prevent recurrent ischemic episodes.

  2. Tricuspid insufficiency detected by equilibrium gated radionuclide study

    International Nuclear Information System (INIS)

    Handler, B.; Pavel, D.G.; Lam, W.; Byrom, E.; Swiryn, S.; Pietras, R.; Rosen, K.M.

    1981-01-01

    The results of a gated radionuclide cardiac study are reported in a patient with biventricular failure and tricuspid insufficiency demonstrated by clinical evaluation, M-mode and 2-D sector echocardiography, and cardia catheterization. The processed gated radionuclide cardiac study showed a left ventricular/right ventricular stroke volume ratio of 0.5; expansion of the hepatic blood pool demonstrated by hepatic time activity curve and calculation of an '''expansion fraction''; and synchronous changes of count rate of the atrial and hepatic regions detected by phase analysis

  3. Evidence of perception of AIDS insufficient for verdict.

    Science.gov (United States)

    1997-11-28

    The 8th U.S. Circuit Court of Appeals overturned the jury verdict in favor of [name removed], a welder who claimed he was fired because his employer, [name removed] National Vendor, thought he had AIDS. According to [name removed], when his health and physical appearance began deteriorating due to Graves disease, a thyroid condition, he was terminated. [Name removed] filed a grievance through his labor union and filed a lawsuit under the Americans with Disabilities Act (ADA). The Circuit Court panel determined there was insufficient evidence to conclude that the company's officials and key decision makers regarded [name removed] as having AIDS.

  4. Endovascular therapy for chronic cerebrospinal venous insufficiency in multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Marc A. Lazzaro

    2011-07-01

    Full Text Available Recent reports have emerged suggesting that multiple sclerosis (MS may be due to abnormal venous outflow from the central nervous system, termed Chronic Cerebrospinal Venous Insufficiency (CCSVI. These reports have generated strong interest and controversy over the prospect of a treatable cause of this chronic debilitating disease. This review aims to describe the proposed association between CCSVI and MS, summarize the current data, and discuss the role of endovascular therapy and the need for rigorous randomized clinical trials to evaluate this association and treatment.

  5. French Military Intervention in Mali: Inevitable, Consensual yet Insufficient

    Directory of Open Access Journals (Sweden)

    Isaline Bergamaschi

    2013-06-01

    Full Text Available This practice note offers an account of France’s military intervention in Mali launched on 11 January 2013. Firstly, it provides an analysis of the events that led up to the dual crisis in the country’s northern and southern regions and to a new wave of armed conflict between government and rebel forces. Then, it is argued that although the French military intervention was framed as inevitable and based on a broad consensus, it will nevertheless be insufficient to address the root sociopolitical causes of Mali´s multidimensional crisis.

  6. THE METHOD OF MANAGEMENT WOMEN WITH ISTHMIC-CERVICAL INSUFFICIENCY

    Directory of Open Access Journals (Sweden)

    Мария Сергеевна Воронцова

    2018-01-01

    Full Text Available Isthmic-cervical insufficiency (ICI is one of the most common causes of spontaneous premature births. In II trimester of pregnancy in the structure of miscarriages, the share of ICI accounts for about 40 % of cases. The purpose – evaluate the effectiveness of the complex method of correction of isthmic-cervical insufficiency. Materials and methods. A simple, open, prospective, randomized study was performed on the basis of the City Clinical Perinatal Center in Omsk. Under observation, there were 60 patients aged 18-40 years in gestation period of 13-33 weeks 6 days with a proven diagnosis of «isthmic-cervical insufficiency». The main group included 30 patients who received treatment with a new combined method: the obstetric pessary «CVK», which differs from the analogues by a more anatomical ellipsoidal form and an increased number of perforations to improve the outflow of vaginal secretions in combination with intravaginal injection of micronized progesterone in a dosage of 100 mg 2 times a day and a drug normalizing the biocenosis of the vagina, as a lyophilized culture of lactobacilli L. casei rhamnosus Doderleini in a dosage of 340 mg, 1 capsule intravaginally at night 2 times a week. The comparison group consisted of 30 patients who received treatment: obstetric silicone pessary + micronized progesterone at a dosage of 200 mg per day intravaginally. The outcomes of pregnancy and childbirth were evaluated. Results. The total number of premature births in the main group was 4 (13.3 % compared to 12 (40 % in the comparison group (p = 0,023. Based on the results of the study, a statistically significant reduction in patients with recurrent vaginal flora (p = 0,0001 was obtained and, due to a decrease in this indicator, a general decrease in the number of women with complications of pregnancy was registered (p = 0,019. The conclusion. The proposed method of correction of isthmic-cervical insufficiency is more effective

  7. Distal vertebral artery reconstruction when managing vertebrobasilar insufficiency

    Directory of Open Access Journals (Sweden)

    D. M. Galaktionov

    2017-11-01

    Full Text Available This article presents a literature review devoted to the reconstruction of the distal vertebral artery and a clinical case of successful surgical treatment of a patient suffering from vertebrobasilar insufficiency caused by occlusion of the vertebral artery in a proximal segment. The external carotid artery-distal vertebral artery bypass was performed by using the radial artery.Received 27 February 2017. Revised 25 July 2017. Accepted 3 August 2017.Funding: The study did not have sponsorship.Conflict of interest: The authors declare no conflict of interest. 

  8. VENOUS INSUFFICIENCY AND THROMBOEMBOLIC DISEASE IN BARIATRIC SURGERY PATIENTS

    Directory of Open Access Journals (Sweden)

    Bonno van BELLEN

    2013-09-01

    Full Text Available Context Morbid obesity is associated with various co-morbidities, including chronic venous insufficiency. Bariatric surgery is the only effective treatment for morbid obesity, but with potential risks and possible complications, including venous thromboembolism. Objective To determine the prevalence of clinical and ultrasonographic signs of chronic venous insufficiency in morbid obese patients in preparation for bariatric surgery and the incidence of post-operative venous thromboembolic disease. Methods Patients on work-up for bariatric surgery of Centro Terapêutico Especializado em Fígado (CETEFI and Pro-Gastro surgical teams of the Hospital Beneficência Portuguesa de São Paulo were included. The analysed data were pre-operative findings for venous insufficiency (CEAP - clinical, etiological, anatomical, physiopathologic - classification and venous ultrassonographic findings, type of surgery (open or laparoscopic, abdominal circumference, body mass index (BMI and post-operative ultrassonography search for venous insufficiency and deep venous thrombosis. Results Between March 2007 and December 2009, 95 patients candidates for bariatric surgery had clinical and duplex scan evaluation of the lower limbs venous system. Of the 95 patients, 53 were submitted to the surgical procedure. There was a predominance of women (77.9%, the average age was 38.5 years, average preoperative weight 124.6 kg and average BMI of 45.5 kg/m2. Regarding obesity, 16.8% were obese, and 83.1% were morbidly obese. In relation to the venous findings, 86.3% of the patients did fit CEAP classification less than 3 and 13.7% greater than or equal to 3. Among the post-operative complications, there were four cases of wound infection. Three patients developed post-operative distal venous thrombosis (7.5%, but no one had clinically manifested pulmonary embolism. Conclusion No relation between BMI, CEAP classification and venous ultrassonographic findings were found. Although

  9. Geographic information system-based healthcare waste management planning for treatment site location and optimal transportation routeing.

    Science.gov (United States)

    Shanmugasundaram, Jothiganesh; Soulalay, Vongdeuane; Chettiyappan, Visvanathan

    2012-06-01

    In Lao People's Democratic Republic (Lao PDR), a growth of healthcare centres, and the environmental hazards and public health risks typically accompanying them, increased the need for healthcare waste (HCW) management planning. An effective planning of an HCW management system including components such as the treatment plant siting and an optimized routeing system for collection and transportation of waste is deemed important. National government offices at developing countries often lack the proper tools and methodologies because of the high costs usually associated with them. However, this study attempts to demonstrate the use of an inexpensive GIS modelling tool for healthcare waste management in the country. Two areas were designed for this study on HCW management, including: (a) locating centralized treatment plants and designing optimum travel routes for waste collection from nearby healthcare facilities; and (b) utilizing existing hospital incinerators and designing optimum routes for collecting waste from nearby healthcare facilities. Spatial analysis paved the way to understand the spatial distribution of healthcare wastes and to identify hotspots of higher waste generating locations. Optimal route models were designed for collecting and transporting HCW to treatment plants, which also highlights constraints in collecting and transporting waste for treatment and disposal. The proposed model can be used as a decision support tool for the efficient management of hospital wastes by government healthcare waste management authorities and hospitals.

  10. AREVA la Hague site information report. Written in compliance with Article L. 125-15 of the French Environmental Code - 2015 edition

    International Nuclear Information System (INIS)

    2016-01-01

    This document is the annual information report required by Article L. 125-15 of the Environmental Code, which states that any operator of a regulated nuclear facility draws up a report each year containing information on: - measures taken to prevent or limit the risks or drawbacks that the facility may present for the interests mentioned in Article L. 593-1; - incidents and accidents occurring within the facility's perimeter subject to the reporting obligation under Article L. 591-5, together with the measures taken to limit their development and the consequences for human health and the environment; - the type and results of measurements of radioactive and non-radioactive releases from the facility to the environment; - the type and quantity of waste stored within the facility's perimeter together with the measures taken to limit their volumes and health and environmental impacts, in particular on soils and water. In accordance with the provisions of Article L. 125-16 of the Environmental Code, this report is submitted to the site's Health, Safety and Working Conditions Committee (CHSCT, Comite d'hygiene, de securite et des conditions de travail), which may formulate recommendations. Those recommendations are appended to the document for purposes of publication and transmission. The report presents, first, the Areva La Hague site with its facilities and activities in relation with spent fuel reprocessing and radioactive waste management. Then, it takes stock of the dispositions implemented for the limitation and prevention of risks and summarizes the events declared in 2015. Next, it presents the management of the site effluents and wastes and the environmental monitoring. Finally, the actions of public information are presented

  11. SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - NPL Sites

    Data.gov (United States)

    U.S. Environmental Protection Agency — National Priorities List (NPL) Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) (Superfund) Public Access...

  12. Allegheny County Illegal Dump Sites

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Illegal Dump Site dataset includes information on illegal dump sites, their type of trash, and the estimate tons of trash at each site. The information was...

  13. Detecting changes in wetland morphology using a geographic information system: Historical database application at the Savannah River Site

    International Nuclear Information System (INIS)

    Christel-Rose, L.M.

    1993-01-01

    New policies regarding the ''no net loss'' of wetlands has presented resource managers and GIS analysts with a challenging ecological application. Historical aerial photography provides a temporal record of conditions over time. Access to temporal data sources is beneficial when appraising wetland gain and loss because man-made disturbances can have both short and long term effects on wetland communities. This is particularly true when trying to assess the existing communities for the specific purpose of restoration and reclamation of the ecologic structure and function of the community prior to a disturbance. Remediation efforts can be optimized when definitive documentation exists of the original communities. The Geographic Information System (GIS) is a powerful tool for integrating these data sets and performing spatial and temporal analyses in support of ecological applications

  14. The Soft Palate Friendly Speech Bulb for Velopharyngeal Insufficiency.

    Science.gov (United States)

    Kahlon, Sukhdeep Singh; Kahlon, Monaliza; Gupta, Shilpa; Dhingra, Parvinder Singh

    2016-09-01

    Velopharyngeal insufficiency is an anatomic defect of the soft palate making palatopharyngeal sphincter incomplete. It is an important concern to address in patients with bilateral cleft lip and palate. Speech aid prosthesis or speech bulbs are best choice in cases where surgically repaired soft palate is too short to contact pharyngeal walls during function but these prosthesis have been associated with inadequate marginal closure, ulcerations and patient discomfort. Here is a case report of untreated bilateral cleft lip and palate associated with palatal insufficiency treated by means of palate friendly innovative speech bulb. This modified speech bulb is a combination of hard acrylic and soft lining material. The hard self-curing acrylic resin covers only the hard palate area and a permanent soft silicone lining material covering the soft palate area. A claw-shaped wire component was extended backwards from acrylic and was embedded in soft silicone to aid in retention and approximation of two materials. The advantage of adding the soft lining material in posterior area helped in covering the adequate superior extension and margins for maximal pharyngeal activity. This also improved the hypernasality, speech, comfort and overall patient acceptance.

  15. Cognitive function in patients with primary adrenal insufficiency (Addison's disease).

    Science.gov (United States)

    Schultebraucks, Katharina; Wingenfeld, Katja; Heimes, Jana; Quinkler, Marcus; Otte, Christian

    2015-05-01

    Patients with primary adrenal insufficiency (AI) need to replace glucocorticoids and mineralocorticoids that act on glucocorticoid (GR) and mineralocorticoid receptors (MR). Both receptors are highly expressed in the hippocampus and are closely associated with cognitive function, which might be impaired by insufficient or increased GR and MR stimulation. However, little is known about cognitive function in patients with AI. It was examined whether patients with AI exhibit worse cognitive function compared to sex-, age-, and education-matched controls. Cognitive function (executive function, concentration, verbal memory, visual memory, working memory, and autobiographical memory) was assessed in 30 patients with AI (mean age 52.4 yrs. ±14.4, n=21 women, mean duration of illness 18.2 yrs. ±11.1) and 30 matched controls. We also measured depressive symptoms, body mass index (BMI), and blood pressure. Patients with AI showed more depressive symptoms, had a greater BMI and lower systolic blood pressure compared to controls. Adjusted analyses controlling for these variables revealed that patients with AI performed significantly worse in verbal learning (F=7.8, p=.007). Executive function, concentration, working memory, verbal memory, visuospatial memory, and autobiographical memory did not differ between groups. No clinically relevant cognitive impairment was found in patients with AI compared to matched controls. Even long-term glucocorticoid and mineralocorticoid substitution over almost two decades appears to have only subtle effects on cognition in patients with AI. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. The physical mechanism of successful treatment for cervical insufficiency

    Science.gov (United States)

    Baumer, Alexa; Amechi, Alexis; Codrington, Paige; Leftwich, Megan C.

    2017-11-01

    Cervical insufficiency is a medical condition during pregnancy in which the uterine cervix softens and begins to dilate before reaching full term, usually between 18 and 22 weeks gestation. It is the most common cause of second trimester pregnancy loss. One clinical technique used to treat cervical insufficiency is the cervical cerclage, a procedure to close the cervix with a purse-string stitch. There are conflicting findings on the efficacy of a cerclage, with most studies relying on statistical evidence. The purpose of this investigation is to examine the mechanical limitations of a cervical cerclage by pressurizing a stitched, synthetic cervix until rupture. A synthetic model of the cervix is generated using ultrasound images collected by clinical collaborators and fabricated with silicon to imitate physiological properties. Medical residents from The George Washington University Hospital stitch the synthetic cervixes using clinical techniques. Pressure transducers record the maximum force on the stitch before rupture. The results of this study will provide insight into the most effective clinical interventions and the mechanism of their success.

  17. Adolescent Premature Ovarian Insufficiency Following Human Papillomavirus Vaccination

    Directory of Open Access Journals (Sweden)

    Deirdre Therese Little MBBS, DRANZCOG, FACRRM

    2014-10-01

    Full Text Available Three young women who developed premature ovarian insufficiency following quadrivalent human papillomavirus (HPV vaccination presented to a general practitioner in rural New South Wales, Australia. The unrelated girls were aged 16, 16, and 18 years at diagnosis. Each had received HPV vaccinations prior to the onset of ovarian decline. Vaccinations had been administered in different regions of the state of New South Wales and the 3 girls lived in different towns in that state. Each had been prescribed the oral contraceptive pill to treat menstrual cycle abnormalities prior to investigation and diagnosis. Vaccine research does not present an ovary histology report of tested rats but does present a testicular histology report. Enduring ovarian capacity and duration of function following vaccination is unresearched in preclinical studies, clinical and postlicensure studies. Postmarketing surveillance does not accurately represent diagnoses in adverse event notifications and can neither represent unnotified cases nor compare incident statistics with vaccine course administration rates. The potential significance of a case series of adolescents with idiopathic premature ovarian insufficiency following HPV vaccination presenting to a general practice warrants further research. Preservation of reproductive health is a primary concern in the recipient target group. Since this group includes all prepubertal and pubertal young women, demonstration of ongoing, uncompromised safety for the ovary is urgently required. This matter needs to be resolved for the purposes of population health and public vaccine confidence.

  18. Urinary hemosiderin: role in evaluation of chronic venous insufficiency

    Directory of Open Access Journals (Sweden)

    Ashish Lal Shrestha

    2012-08-01

    Full Text Available Chronic venous insufficiency (CVI leads to skin changes with dermal hemosiderin deposition. We studied the presence of hemosiderin in the urine to assess if this could be used as a biochemical marker for CVI. Hereby we present a case control study conducted in a tertiary care centre in South India. There were 100 cases with evidence of advanced CVI (the Clinical-Etiology-Anatomy-Pathophysiology classification: C5, C6 confirmed by duplex scanning. Controls were 50 patients with leg ulcers due to other etiologies. All patients were subjected to urinary hemosiderin testing. In all 100 patients with CVI (C5 and C6 disease axial venous reflux was confirmed by duplex ultrasound. Superficial venous reflux was noted in 71% of patients and deep venous reflux in 54.%. Primary venous insufficiency was the etiology in 81% of patients. Only 4/100 patients had detectable amounts of hemosiderin in the urine. Urine hemosiderin testing to determine presence or absence of CVI yielded the following values: positive predictive value-80%; negative predictive value-33%; sensitivity-4% and specificity-98%. The test could not be recommended as a marker of CVI. In Indian patients urinary hemosiderin is not a useful screening test in CVI.

  19. Autoimmune hyperthyroidism due to secondary adrenal insufficiency: resolution with glucocorticoids.

    Science.gov (United States)

    Skamagas, Maria; Geer, Eliza B

    2011-01-01

    To describe the course of autoimmune hyperthyroid disease in a patient with corticotropin (ACTH) deficiency treated with glucocorticoids. We report the clinical presentation, laboratory data, imaging studies, and management of a patient with weight loss, fatigue, apathy, hallucinations, and arthritis. Autoimmune hyperthyroidism (positive thyroperoxidase and thyroglobulin antibodies and borderline positive thyrotropin receptor antibody) was diagnosed in a 71-year-old woman. New psychotic symptoms prompted brain magnetic resonance imaging, which revealed a partially empty sella. Undetectable morning cortisol, undetectable ACTH, and failure to stimulate cortisol with synthetic ACTH (cosyntropin 250 mcg) secured the diagnosis of long-standing secondary adrenal insufficiency. Hydrocortisone replacement improved the patient's symptoms, resolved the thyroid disease, and decreased thyroid antibody titers. In retrospect, the patient recalled severe postpartum hemorrhage requiring blood transfusion at age 38 years. A Sheehan event probably occurred 33 years before the patient presented with corticotropin deficiency. Hyperthyroidism accelerated cortisol metabolism and provoked symptoms of adrenal insufficiency. The hypocortisolemic state may precipitate hyperimmunity and autoimmune thyroid disease. Rapid resolution of hyperthyroidism and decreased thyroid antibody titers with glucocorticoid treatment support this hypothesis.

  20. Insufficiency Fractures After Pelvic Radiotherapy in Patients With Prostate Cancer

    International Nuclear Information System (INIS)

    Igdem, Sefik; Alco, Guel; Ercan, Tuelay; Barlan, Metin; Ganiyusufoglu, Kuersat; Unalan, Buelent; Turkan, Sedat; Okkan, Sait

    2010-01-01

    Purpose: To assess the incidence, predisposing factors, and clinical characteristics of insufficiency fractures (IF) in patients with prostate cancer, who received pelvic radiotherapy as part of their definitive treatment. Methods and Materials: The charts of 134 prostate cancer patients, who were treated with pelvic radiotherapy between 1998 and 2007 were retrospectively reviewed. IF was diagnosed by bone scan and/or CT and/or MRI. The cumulative incidence of symptomatic IF was estimated by actuarial methods. Results: Eight patients were identified with symptomatic IF after a median follow-up period of 68 months (range, 12-116 months). The 5-year cumulative incidence of symptomatic IF was 6.8%. All patients presented with lower back pain. Insufficiency fracture developed at a median time of 20 months after the end of radiotherapy and was managed conservatively without any need for hospitalization. Three patients were thought to have metastatic disease because of increased uptake in their bone scans. However, subsequent CT and MR imaging revealed characteristic changes of IF, avoiding any further intervention. No predisposing factors for development of IF could be identified. Conclusions: Pelvic IF is a rare complication of pelvic radiotherapy in prostate cancer. Knowledge of pelvic IF is essential to rule out metastatic disease and prevent unnecessary treatment, especially in a patient cohort with high-risk features for distant spread.

  1. Computer Programs for Obtaining and Analyzing Daily Mean Steamflow Data from the U.S. Geological Survey National Water Information System Web Site

    Science.gov (United States)

    Granato, Gregory E.

    2009-01-01

    Streamflow information is important for many planning and design activities including water-supply analysis, habitat protection, bridge and culvert design, calibration of surface and ground-water models, and water-quality assessments. Streamflow information is especially critical for water-quality assessments (Warn and Brew, 1980; Di Toro, 1984; Driscoll and others, 1989; Driscoll and others, 1990, a,b). Calculation of streamflow statistics for receiving waters is necessary to estimate the potential effects of point sources such as wastewater-treatment plants and nonpoint sources such as highway and urban-runoff discharges on receiving water. Streamflow statistics indicate the amount of flow that may be available for dilution and transport of contaminants (U.S. Environmental Protection Agency, 1986; Driscoll and others, 1990, a,b). Streamflow statistics also may be used to indicate receiving-water quality because concentrations of water-quality constituents commonly vary naturally with streamflow. For example, concentrations of suspended sediment and sediment-associated constituents (such as nutrients, trace elements, and many organic compounds) commonly increase with increasing flows, and concentrations of many dissolved constituents commonly decrease with increasing flows in streams and rivers (O'Connor, 1976; Glysson, 1987; Vogel and others, 2003, 2005). Reliable, efficient and repeatable methods are needed to access and process streamflow information and data. For example, the Nation's highway infrastructure includes an innumerable number of stream crossings and stormwater-outfall points for which estimates of stream-discharge statistics may be needed. The U.S. Geological Survey (USGS) streamflow data-collection program is designed to provide streamflow data at gaged sites and to provide information that can be used to estimate streamflows at almost any point along any stream in the United States (Benson and Carter, 1973; Wahl and others, 1995; National

  2. GEOGRAPHIC INFORMATION SYSTEM-BASED MODELING AND ANALYSIS FOR SITE SELECTION OF GREEN MUSSEL, Perna viridis, MARICULTURE IN LADA BAY, PANDEGLANG, BANTEN PROVINCE

    Directory of Open Access Journals (Sweden)

    I Nyoman Radiarta

    2011-06-01

    Full Text Available Green mussel is one of important species cultured in Lada Bay, Pandeglang. To provide a necessary guidance regarding green mussel mariculture development, finding suitable site is an important step. This study was conducted to identify suitable site for green mussel mariculture development using geographic information system (GIS based models. Seven important parameters were grouped into two submodels, namely environmental (water temperature, salinity, suspended solid, dissolve oxygen, and bathymetry and infrastructural (distance to settlement and pond aquaculture. A constraint data was used to exclude the area from suitability maps that cannot be allowed to develop green mussel mariculture, including area of floating net fishing activity and area near electricity station. Analyses of factors and constraints indicated that about 31% of potential area with bottom depth less than 25 m had the most suitable area. This area was shown to have an ideal condition for green mussel mariculture in this study region. This study shows that GIS model is a powerful tool for site selection decision making. The tool can be a valuable tool in solving problems in local, regional, and/or continent areas.

  3. Primary Ovarian Insufficiency Induced by Fanconi Anemia E Mutation in a Mouse Model.

    Science.gov (United States)

    Fu, Chun; Begum, Khurshida; Overbeek, Paul A

    2016-01-01

    In most cases of primary ovarian insufficiency (POI), the cause of the depletion of ovarian follicles is unknown. Fanconi anemia (FA) proteins are known to play important roles in follicular development. Using random insertional mutagenesis with a lentiviral transgene, we identified a family with reduced fertility in the homozygous transgenic mice. We identified the integration site and found that the lentivirus had integrated into intron 8 of the Fanconi E gene (Fance). By RT-PCR and in situ hybridization, we found that Fance transcript levels were significantly reduced. The Fance homozygous mutant mice were assayed for changes in ovarian development, follicle numbers and estrous cycle. Ovarian dysplasias and a severe lack of follicles were seen in the mutant mice. In addition, the estrous cycle was disrupted in adult females. Our results suggest that POI has been induced by the Fance mutation in this new mouse model.

  4. Chronic triceps insufficiency managed with extensor carpi radialis longus and palmaris longus tendon grafts.

    Science.gov (United States)

    Singh, Dhanpal; Kumar, K Arun; Dinesh, Mc; Raj, Ranju

    2012-03-01

    Chronic triceps insufficiency, causing prolonged disability, occurs due to a missed diagnosis of an acute rupture. We report a 25 year old male with history of a significant fall sustaining multiple injuries. Since then, he had inability in extending his right elbow for which he sought intervention after a year. Diagnosis of triceps rupture was made clinicoradiologically and surgery was planned. Intraoperative findings revealed a deficient triceps with a fleck of avulsed bone from olecranon. Ipsilateral double tendon graft including extensor carpi radialis longus and palmaris longus were anchored to triceps and secured with the olecranon. Six-months follow revealed a complete active extension of elbow and a full function at the donor site.

  5. Percutaneous sclerotherapy of testicular vein insufficiency in persistent and recurrent varicocele

    International Nuclear Information System (INIS)

    Sigmund, G.; Baehren, W.; Gall, H.; Thon, W.

    1986-01-01

    Among 1217 retrograde phlebographies of left-sided idiopathic varicoceles 66 patients presented because of persistence or recurrence of varicocele, 34 of them after operation and 32 after sclerotherapy. After operation without success there was always - except for one case - a reflux passing the site of ligature. If persistence or recurrence of varicocele occured after sclerotherapy, the testicular (internal spermatic) vein was most often found to be obliterated at the junction with the renal vein and the sonographically proven reflux went via collaterals or unidentified veins which prevented a repeat sclerotheraphy. In 12 out of 32 patients after sclerotherapy a persistent main stem of the testicular vein allowed a second attempt of sclerotherapy. If sclerotherapy in patients after operation or previous sclerotherapy could be performed, it was an effective, low risk procedure on an outpatient basis just as in primary sclerotherapy of testicular vein insufficiency causing varicocele. (orig.) [de

  6. Methodology and parameters for assessing human health effects for waste sites at the Savannah River Plant: Environmental information document

    International Nuclear Information System (INIS)

    King, C.M.; Marter, W.L.; Looney, B.B.; Pickett, J.B.

    1987-03-01

    This report provides a summary of the components of risk assessment and presents the technical basis for application of the risk evaluation process to the principal pollutants at SRP: radionuclides, toxic chemicals, and carcinogenic compounds. An extensive technical data base from the fields of radiation health physics, toxicology, and environmental sciences is required to accomplish this task. The origin and meaning of this data base is summarized for each class of contaminant and parameter values provided for use in numerical analysis of risk. The process of risk assessment is associated with uncertainties, a fact which is frequently stated in the technical literature addressing this subject. A review of risk assessment uncertainties and the limitations of predictive risk assessment are summarized. Risk estimators for each class of contaminants at the SRP have been tabulated for radionuclides, toxic chemicals, and carcinogens from the technical literature. Estimation of human health risk is not an additive process for radiation effects and chemical carcinogenesis since their respective dosimetric models are distinctly different even though the induction of cancer is reported to be the common end result. It is recommended in this report that risk estimation for radionuclides and chemical carcinogens should be tabulated separately and this recommendation has been applied in all environmental information documentation published by the Savannah River Laboratory. Impacts due to toxic chemicals in the biosphere should also be estimated as a separate entity since toxic chemical risk estimators are uniquely different and do not reflect the probability of a detrimental health effect. 23 refs., 4 figs., 13 tabs

  7. Opinion on the radio-ecological monitoring of waters around nuclear installations and on the management of old nuclear waste warehousing sites: 18 recommendations to improve information, transparency and dialogue with involved parties

    International Nuclear Information System (INIS)

    2008-01-01

    After a presentation of the different actors (agencies, institutions, companies) involved in the activities of the various French nuclear installations (base nuclear installations and those concerning the national defence), this report describes the radio-ecological monitoring performed around these nuclear sites: water surveillance on these sites and within their environment, regulatory requirements on effluents and surveillance, information provided by operators and by institutional organisations, assessment of the radio-ecological status of nuclear sites and of potential environmental and health impacts. It describes regulatory obligation in terms of public information, information and communication actions, and gives an assessment of the High committee about public information quality. It discusses ways to improve this quality for a higher transparency, to reinforce the role of local information commissions (CLI), and improve site monitoring. All these aspects are grouped in 18 recommendations

  8. Nature exposure sufficiency and insufficiency: The benefits of environmental preservation.

    Science.gov (United States)

    Reddon, John R; Durante, Salvatore B

    2018-01-01

    Increasing industrialization, urbanization, and a failure of many world leaders to appreciate the consequences of climate change are deleteriously impacting quality of life as well as diminishing the prospects for long term survival. Economic competitiveness and corporate profitability often pre-empt environmental concerns. The calving of an iceberg in Antarctica and the hurricane activity in the Caribbean during 2017 are unfortunate illustrations of the continuing escalation of environmental issues. We provide historical and current evidence for the importance of Nature Exposure (NE) and introduce the continuum Nature Exposure Sufficiency (NES) and Insufficiency (NEI). Insufficiency includes impoverished environments (e.g., slums and prisons) where nature exposure is very limited. Nature Exposure Sufficiency (NES) is an optimal amount of exposure to nature where many benefits such as reinvigoration can be obtained by everyone. NES also has several benefits for individuals with various health conditions such as arthritis, dementia, or depression. The benefits of NE are not just derivable from parks, forests, and other natural settings. Interiors of buildings and homes can be enhanced with plants and even pictures or objects from nature. Additionally, there is abundant evidence indicating that virtual and artificial environments depicting nature can provide substantial NE and therefore contribute to general wellbeing. Besides the difficulty in achieving cooperation amongst nations, corporations, and other collectives in developing and implementing long range plans to deal with climate change, there is also sometimes an aversion at the individual level whereby people are unwilling to experience nature due to insects and other discomforts. Such individuals are often averse to supplanting the comforts of home, even temporarily, with inadequate facilities that are seemingly less pleasant than their typical dwellings. We propose using the term Nature Exposure Aversion

  9. Efficacy and safety of benazepril for advanced chronic renal insufficiency.

    Science.gov (United States)

    Hou, Fan Fan; Zhang, Xun; Zhang, Guo Hua; Xie, Di; Chen, Ping Yan; Zhang, Wei Ru; Jiang, Jian Ping; Liang, Min; Wang, Guo Bao; Liu, Zheng Rong; Geng, Ren Wen

    2006-01-12

    Angiotensin-converting-enzyme inhibitors provide renal protection in patients with mild-to-moderate renal insufficiency (serum creatinine level, 3.0 mg per deciliter or less). We assessed the efficacy and safety of benazepril in patients without diabetes who had advanced renal insufficiency. We enrolled 422 patients in a randomized, double-blind study. After an eight-week run-in period, 104 patients with serum creatinine levels of 1.5 to 3.0 mg per deciliter (group 1) received 20 mg of benazepril per day, whereas 224 patients with serum creatinine levels of 3.1 to 5.0 mg per deciliter (group 2) were randomly assigned to receive 20 mg of benazepril per day (112 patients) or placebo (112 patients) and then followed for a mean of 3.4 years. All patients received conventional antihypertensive therapy. The primary outcome was the composite of a doubling of the serum creatinine level, end-stage renal disease, or death. Secondary end points included changes in the level of proteinuria and the rate of progression of renal disease. Of 102 patients in group 1, 22 (22 percent) reached the primary end point, as compared with 44 of 108 patients given benazepril in group 2 (41 percent) and 65 of 107 patients given placebo in group 2 (60 percent). As compared with placebo, benazepril was associated with a 43 percent reduction in the risk of the primary end point in group 2 (P=0.005). This benefit did not appear to be attributable to blood-pressure control. Benazepril therapy was associated with a 52 percent reduction in the level of proteinuria and a reduction of 23 percent in the rate of decline in renal function. The overall incidence of major adverse events in the benazepril and placebo subgroups of group 2 was similar. Benazepril conferred substantial renal benefits in patients without diabetes who had advanced renal insufficiency. (ClinicalTrials.gov number, NCT00270426.) Copyright 2006 Massachusetts Medical Society.

  10. Recurrent Tricuspid Insufficiency: Is the Surgical Repair Technique a Risk Factor?

    OpenAIRE

    Kara, Ibrahim; Koksal, Cengiz; Cakalagaoglu, Canturk; Sahin, Muslum; Yanartas, Mehmet; Ay, Yasin; Demir, Serdar

    2013-01-01

    This study compares the medium-term results of De Vega, modified De Vega, and ring annuloplasty techniques for the correction of tricuspid insufficiency and investigates the risk factors for recurrent grades 3 and 4 tricuspid insufficiency after repair.

  11. Effectiveness of vision therapy in school children with symptomatic convergence insufficiency

    Directory of Open Access Journals (Sweden)

    Jung Un Jang

    2017-01-01

    Conclusion: Among convergence insufficiency symptoms, the following improved in particular: near point of convergence, exophoria, and near positive fusional vergence. These findings suggest that vision therapy is very effective to recover from symptomatic convergence insufficiency.

  12. Percutaneous intervention in the menagement of insufficient native arteriovenous hemodialysis fistulae

    International Nuclear Information System (INIS)

    Kim, Hye Jung; Seong, Chang Kyu; Kwon, Jae Hyun; Kim, Young Hwan; Park, Noh Hyuck; Kim, Tae Hun; Kim, Yong Joo; Kang, Duck Sik; Shin, Tae Beom

    2002-01-01

    To determine the effectiveness and patency of percutaneous intervention in insufficient native arteriovenous hemodialysis fistulae (AVFs). Between March 1997 and September 2001, 67 cases of insufficient native AVFs resulted from central vein lesion, PTA was performed in 48 cases, and thrombolytic therapy with or without PTA in 11. In eight of the cases, in which central vein stenosis had led to the insufficency, percutaneous transluminal angioplasty (PTA) was performed, and in three of the eight, a stent was inserted. Angiography findings and complications, as well as success and patency rates in the non-thrombosis and thrombosis group, were evaluated; the central vein lesion group was analysed separately. Among 84 lesions observed at angiography, three were 54 cases of stenosis, 17 of occlusion, and 13 of combined thrombosis. The lesions were located in a proximal vein (n=51), distal vein (n=14), artery (n=6), and at the site of anastomosis (n=13). In the central vein lesion group (n=8), seven cases of stenosis and one of occlusion were noted. The overall procedural success rate was 79.1% (53/67). That is, in patients with no central vein lesion, the procedural success rate of PTA of native AVFs was 85.4% (41/48) and the patency rates of this were 83.1% at 6 months and 67.4% at 12 months. In cases of thrombolysis with/without PTA, the procedural success rate was 54.5% (6/11) and the patency rates were 83.3% at 6 months and 62.5% at 12 months. Finally, in patients with a central vein lesion, the procedural success rate was 75% (6/8) and the patency rates were 80% at 6 months and 30% at 12 months. There was one case of pseudoaneurysm formation at the puncture site of the brachial artery, which was used as the access route for intervention; one embolism in the brachial artery; and three cases of vascular spasm and two of hematoma which did not require active treatment. Percutaneous intervention offers effective and safe management of insufficient AVFs. The procedural

  13. Post-traumatic tricuspid insufficiency: a case report.

    Science.gov (United States)

    Tütün, Ufuk; Aksöyek, Ayşen; Parlar, Ali Ihsan; Cobanoğlu, Adnan

    2011-11-01

    Post-traumatic tricuspid insufficiency is a rare complication of chest trauma. An 18-year-old male patient was injured in a bicycle accident from his abdominal and anterior chest wall. The tear on the inferior diaphragmatic surface of the heart was repaired with primary sutures by the attending surgeon. Eighteen years later, he was admitted to the hospital with severe tricuspid regurgitation (3+/4+). During the operation, the valve was determined unsuitable for repair and was replaced with a bioprosthesis. The hemodynamic aberrations relevant to an isolated tricuspid valve injury are very often well-tolerated. Reconstructive surgery may be possible in the early period. In the late cases, repair is sometimes not feasible due to degeneration of the valvular apparatus. Replacement with a biological prosthesis may give the best long-term results in longstanding cases.

  14. Uncertainties in endocrine substitution therapy for central endocrine insufficiencies: hypothyroidism.

    Science.gov (United States)

    Persani, Luca; Bonomi, Marco

    2014-01-01

    In patients with primary hypothyroidism (PH), L-T4 replacement therapy can safely be adjusted to the individual needs by testing serum thyrotropin (TSH) concentration exclusively. Central hypothyrodism (CeH) is a particular hypothyroid condition due to an insufficient stimulation by TSH of an otherwise normal thyroid gland. CeH is about 1000-fold rarer than PH and raises several challenges for clinicians, mainly because they cannot rely on the systematic use of the reflex TSH strategy for diagnosis or therapy monitoring. Therefore, L-T4 replacement in CeH should rely on the combined evaluation of several biochemical and clinical parameters in order to overcome the lack of accuracy of the single index. The management of CeH replacement is further complicated by the frequent combination with other pituitary deficiencies and their treatment. © 2014 Elsevier B.V. All rights reserved.

  15. Speech Outcomes after Tonsillectomy in Patients with Known Velopharyngeal Insufficiency

    Directory of Open Access Journals (Sweden)

    L. M. Paulson

    2012-01-01

    Full Text Available Introduction. Controversy exists over whether tonsillectomy will affect speech in patients with known velopharyngeal insufficiency (VPI, particularly in those with cleft palate. Methods. All patients seen at the OHSU Doernbecher Children's Hospital VPI clinic between 1997 and 2010 with VPI who underwent tonsillectomy were reviewed. Speech parameters were assessed before and after tonsillectomy. Wilcoxon rank-sum testing was used to evaluate for significance. Results. A total of 46 patients with VPI underwent tonsillectomy during this period. Twenty-three had pre- and postoperative speech evaluation sufficient for analysis. The majority (87% had a history of cleft palate. Indications for tonsillectomy included obstructive sleep apnea in 11 (48% and staged tonsillectomy prior to pharyngoplasty in 10 (43%. There was no significant difference between pre- and postoperative speech intelligibility or velopharyngeal competency in this population. Conclusion. In this study, tonsillectomy in patients with VPI did not significantly alter speech intelligibility or velopharyngeal competence.

  16. Refractory Hyperlactatemia with Organ Insufficiency in Lipid Storage Myopathy.

    Science.gov (United States)

    Xu, Yuanda; Zhou, Li; Liang, Weibo; He, Weiqun; Liu, Xiaoqing; Liang, Xiuling; Zhong, Nanshan; Li, Yimin

    2015-08-01

    Lipid storage myopathy is a metabolic disorder characterized by abnormal lipid accumulation in muscle fibers and progressive muscle weakness. Here, we report the case of a 17-year-old woman with progressive muscle weakness, refractory hyperlactatemia, and multiple organ insufficiency. Severe pneumonia was the initial diagnosis. After anti-infective treatment, fluid resuscitation, and mechanical ventilation, the patient's symptoms improved but hyperlactatemia and muscle weakness persisted. She was empirically treated with carnitine. Biochemical tests, electromyography, and muscle biopsy confirmed lipid storage myopathy. After 7 weeks of treatment, the patient resumed normal daily life. An empirical treatment with carnitine may be beneficial for patients before an accurate diagnosis of lipid storage myopathy is made.

  17. Nuclear power as a necessary option, albeit in insufficient one

    International Nuclear Information System (INIS)

    Altin, V.

    2007-01-01

    In this presentation a comparative assessment of known energy resources are made with respect to their energy densities. Fossil fuels have formed the foundation of a worldwide economic development realized throughout the 20th century. Their comparatively high energy densities have made faster energy flows and thereby higher power levels and speedy development possible. However, renewable sources that are already feasible have much lower levels of energy densities. Their large scale utilization in lieu of fossil fuels would necessitate either reduction of economic growth rates to 'sustainable' levels or speedy development of feasible large scale storage technologies. Nuclear energy appears to impose itself as a necessity to alleviate this transition period, albeit within the constraint of known uranium reserves an insufficient one

  18. The musculoskeletal radiologic findings associated with chronic renal insufficiency

    International Nuclear Information System (INIS)

    Ruiz, P.J.; Gomez, I.; Hernandez, L.; Relanzon, S.; Hurtado, M.

    1997-01-01

    The numerous musculoskeletal changes associated with chronic renal insufficiency (CRI) are detected with increasing frequency since hemodialysis and kidney transplantation have prolonged the survival of these patients. These signs have been divided into two large groups. The first includes secondary hyperparathyroidism (bone resorption, periostitis and brown tumors), osteoporosis, osteosclerosis, osteomalacia and vascular and soft tissue calcification, all of which are grouped under the term renal osteodystrophy. the second group is composed of miscellaneous disorders including aluminum poisoning, amyloid and crystal deposition, destructive spondyloarthropathy, tendon rupture, infection and avascular necrosis. These changes are less common and occur especially in patients under prolonged hemodialysis or kidney transplant recipients. The detection of musculoskeletal involvement in CRI patients has a considerable impact on their clinical management. The present article reviews the radiological signs of these changes, including representative images that will aid in their recognition. (Author) 33 refs

  19. Neurosarcoidosis-associated central diabetes insipidus masked by adrenal insufficiency.

    Science.gov (United States)

    Non, Lemuel; Brito, Daniel; Anastasopoulou, Catherine

    2015-01-22

    Central diabetes insipidus (CDI) is an infrequent complication of neurosarcoidosis (NS). Its presentation may be masked by adrenal insufficiency (AI) and uncovered by subsequent steroid replacement. A 45-year-old woman with a history of NS presented 2 weeks after abrupt cessation of prednisone with nausea, vomiting, decreased oral intake and confusion. She was diagnosed with secondary AI and intravenous hydrocortisone was promptly begun. Over the next few days, however, the patient developed severe thirst and polyuria exceeding 6 L of urine per day, accompanied by hypernatraemia and hypo-osmolar urine. She was presumed to have CDI due to NS, and intranasal desmopressin was administered. This eventually normalised her urine output and serum sodium. The patient was discharged improved on intranasal desmopressin and oral prednisone. AI may mask the manifestation of CDI because low serum cortisol impairs renal-free water clearance. Steroid replacement reverses this process and unmasks an underlying CDI. 2015 BMJ Publishing Group Ltd.

  20. Primary Ovarian Insufficiency: X chromosome defects and autoimmunity.

    Science.gov (United States)

    Persani, Luca; Rossetti, Raffaella; Cacciatore, Chiara; Bonomi, Marco

    2009-08-01

    Premature ovarian failure (POF) is a primary ovarian defect characterized by absent menarche or premature depletion of ovarian follicles before the age of 40 years. However, in several instances the distinction between definitive or intermittent POF may be difficult on clinical bases, therefore the more appropriate term Primary Ovarian Insufficiency (POI) has been recently proposed and will be used in this review. POI is a heterogeneous disorder affecting approximately 1% of women disappearance of menstrual cycles (secondary amenorrhea) associated with a defective folliculogenesis. POI is generally characterized by low levels of gonadal hormones (estrogens and inhibins) and high levels of gonadotropins (LH and FSH) (hypergonadotropic amenorrhea). Heterogeneity of POI is reflected by the variety of possible causes, including autoimmunity, toxics, drugs, as well as genetic defects. Several data indicate that POI has a strong genetic component. In this manuscript we discuss the X chromosome abnormalities that are associated with POI.