French and International experience on the dialogue around industrial sites; Experience francaise et internationales sur la concertation autour des sites industriels

Energy Technology Data Exchange (ETDEWEB)

Schneider, Th. [Centre d' Etude sur l' Evaluation de la Protection dans le Domaine Nucleaire, CEPN, 92 - Fontenay aux Roses (France); Heriard Dubreuil, G.; Gadbois, S. [Mutadis, 94 - Vitry (France); Oudiz, A. [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Clamart (France); Remond Gouilloud, M. [Paris-6 Univ. Sorbonne, 75 (France)

2002-12-15

This report presents the results of a research work about 'the stakes of the dialogue around the follow up of nuclear and non nuclear industrial installations'. It used the experience of the North Cotentin radioecology group where expertise has been implemented in order to evaluate the impact on health of the releases of the Cogema La Hague plant. This report is the fruit of an interdisciplinary group ( experts of activities with risks, radiation protection, regulation in environment). (N.C.)

French and International experience on the dialogue around industrial sites; Experience francaise et internationales sur la concertation autour des sites industriels

Energy Technology Data Exchange (ETDEWEB)

Schneider, Th [Centre d' Etude sur l' Evaluation de la Protection dans le Domaine Nucleaire, CEPN, 92 - Fontenay aux Roses (France); Heriard Dubreuil, G; Gadbois, S [Mutadis, 94 - Vitry (France); Oudiz, A [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Clamart (France); Remond Gouilloud, M [Paris-6 Univ. Sorbonne, 75 (France)

2002-12-15

This report presents the results of a research work about 'the stakes of the dialogue around the follow up of nuclear and non nuclear industrial installations'. It used the experience of the North Cotentin radioecology group where expertise has been implemented in order to evaluate the impact on health of the releases of the Cogema La Hague plant. This report is the fruit of an interdisciplinary group ( experts of activities with risks, radiation protection, regulation in environment). (N.C.)

How Create an Astronomy Outreach Program to Bring Astronomy to Thousands of People at Outdoor Concerts Astronomy Festivals, or Tourist Sites

Science.gov (United States)

Lubowich, Donald

2015-08-01

I describe how to create an astronomy program for thousands of people at outdoor concerts based on my $308,000 NASA-funded Music and Astronomy Under the Stars (MAUS) program (60 events 2009 - 2013), and the Astronomy Festival on the National Mall (AFNM, 10,000 people/yr).MAUS reached 50,000 music lovers at local parks and at the Central Park Jazz, Newport Folk, Ravinia, or Tanglewood Music Festivals with classical, folk, pop/rock, opera, Caribbean, or county-western concerts assisted by astronomy clubs. Yo-Yo-Ma, the Chicago and Boston Symphony Orchestras, Ravi Coltrane, Esperanza Spalding, Phish, Blood Sweat and Tears, Deep Purple, Tony Orlando, and Wilco performed at these events. AFNM was started in 2010 with co-sponsorship by the White House Office of Science and Technology Policy. MAUS and AFMN combine solar, optical, and radio telescope observations; large posters/banners; hands-on activities, imaging with a cell phone mount; citizen science activities; hand-outs; and teacher info packet. Representatives from scientific institutions participated. Tyco Brahe, Johannes Kepler, and Caroline Herschel made guest appearances.MAUS reached underserved groups and attracted large crowds. Young kids participated in this family learning experience-often the first time they looked through a telescope. While < 50% of the participants took part in a science activity in the past year, they found MAUS enjoyable and understandable; learned about astronomy; wanted to learn more; and increased their interest in science (ave. rating 3.6/4). MAUS is effective in promoting science education!Lessons learned: plan early; create partnerships with parks, concert organizers, and astronomy clubs; test equipment; have backup equipment; create professional displays; select the best location to obtain a largest number of participants; use social media/www sites to promote the events; use many telescopes for multiple targets; project a live image or video; select equipment that is easy to

Variations autour d’un crime

Directory of Open Access Journals (Sweden)

Thanh-Vân Ton-That

1999-01-01

Full Text Available À partir d’une lecture des Châtiments et d’autres textes en prose autour du même thème, nous étudierons les variations de genres et d’écritures de Hugo qui en prose comme en poésie entend dénoncer et émouvoir. L’écriture semble dépasser les cloisonnements génériques et formels dans une prose aux inflexions poétiques et dans des vers où se mêlent narration, description et condamnation d’un crime qui prend alors une valeur universelle.On the basis of the reading of Les Châtiments and other prose texts centered on the same theme, we shall study Hugo’s genre and writing variations. In prose as well as in poetry, he intends to expose and to move. The way in which he writes seems to defy formal and generic classifications through a form of prose which is characterized by poetic overtones, and in lines in which narration and description intermingle with the exposition of a crime which takes on a universal meaning.A partir de una lectura de Châtiments y otros textos en prosa sobre el mismo tema, estudiaremos las variaciones de géneros y escrituras en Hugo quien, en prosa como en poesίa, pretende denunciar y conmover. La escritura parece superar las fronteras genéricas y formales en una prosa llena de inflexiones poéticas y en versos en los que se mezclan narración, descripción y condenación de un crimen que se viste por ende de un valor universal.

Repérer des sites similaires à une recherche par Google

OpenAIRE

Ginouvès, Véronique

2006-01-01

Repérer des sites similaires à une recherche par Google Afficher graphiquement les liens d’un site avec d’autres sites similaires TouchGraph GoogleBrowser crée des agrégations de sites à partir de l’interrogation de Google. Vous visualisez ainsi des nébuleuses de sites à l’intérieur desquelles vous pouvez naviguer facilement, en sautant d'un groupe à l'autre afin de voir les nuages autour de sujets ou de communautés de sujets. Cet outil a été développé par Alex Shapiro, à partir de la version...

Musical Students’ Concert Practice

Directory of Open Access Journals (Sweden)

Aleksandr S. Plokhotnyuk

2012-12-01

Full Text Available . The article presents detailed analysis of performance training of future teachers of music at higher educational establishments and offers ways to overcome the problem of musical students’ concert practice organization.

Dialogue around industrial sites. Synthesis of a thinking method of I.R.S.N; Concertation autour des sites industriels. Synthese d'une demarche de reflexion de l'IRSN

Energy Technology Data Exchange (ETDEWEB)

Sugier, A.; Oudiz, A. [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Clamart (France); Heriard Dubreuil, G.; Gadbois, S. [Mutadis, 94 - Vitry (France); Schneider, Th. [Centre d' Etude sur l' Evaluation de la Protection dans le Domaine Nucleaire CEPN, 92 - Fontenay aux Roses (France)

2003-12-15

The present report gives an account of results on a research work about 'the stakes of the dialogue around the follow up of nuclear and non nuclear industrial facilities' and on conclusions of a seminar, on the same subject that stood at Ville D' Avray from the 21. to 22. of January 2003. This seminar has gathered different actors (administration, experts, associations, industrial operators) concerned by the dialogue around these installations. The work has been directed by I.R.S.N. and had for object to give the knowledge of the French and International experience in matter of dialogue around nuclear and non nuclear industrial sites. (N.C.)

ANALYSIS MUSIC CONCERTS ADOPTING THE MATHEMATICAL MODEL OF HIT PHENOMENA

OpenAIRE

Kawahata Yasuko; Genda Etsuo; Ishii Akira

2013-01-01

A mathematical model for the hit phenomenon in entertainment within a society is presented as a stochastic process of interactions of human dynamics. In this paper, we analyzed music to the concert.Knowing the cost of advertising the concert is difficult. But exposure to the media of the artist can be seen. We tried to analysis of music concert itself by performing a prediction of reputation of artists during the concert tour from this exposure.In this paper, The world most pop...

Acoustic investigations of concert halls for rock music

DEFF Research Database (Denmark)

Adelman-Larsen, Niels Werner; Thompson, Eric Robert; Gade, Anders Christian

2007-01-01

Objective measurement data and subjective evaluations have been collected from 20 small-/medium-sized halls in Denmark used for amplified rhythmic music concerts (pop, rock, jazz). The purpose of the study was to obtain knowledge about optimum acoustic conditions for this type of hall. The study...... is motivated by the fact that most concert tickets sold in Denmark relate to concerts within these genres in this kind of venue. The subjective evaluations were carried out by professional musicians and sound engineers who responded on the basis of their experiences working in these (and other) halls. From...

Cosmos in Concert: Combining astronomy and classical music

Science.gov (United States)

Kremer, Kyle

2018-01-01

Cosmos in Concert is an outreach initiative designed to combine astronomy education with classical music. Over the past several years, this program has presented large-scale multimedia shows for symphony orchestras, educational programs at K-12 schools, and research-oriented university collaborations designed to develop techniques for the sonification of data. Cosmos in Concert has collaborated with institutions including Fermi National Lab, the Adler Planetarium, the Bienen School of Music, and the Colburn School of Music. In this talk, I will give a brief overview of some of the main Cosmos in Concert initiatives and discuss ways these initiatives may be implemented at other institutions.

CONCERT MANAGEMENT IN CROATIA: OBSTACLES AND CHALLENGES

Directory of Open Access Journals (Sweden)

Irina Basara

2016-12-01

Full Text Available The concept of concert management in the Republic of Croatia encounters numerous obstacles in any attempt to institutionalize it. Unlike other countries in the European Union, there is no register of the concert stages, venues as well as facilities for the provision of hearing / consumption of music in the form of performances. Process management organization is incomplete, and institutions that are closely associated with such events do not carry out the classification, categorization and analysis of events that are within the concerts' domain. Commercial music, economically far most cost-effective, is completely ignored and within the framework of cultural events not even the slightest attention is given to it. On the contrary, it is considered the music of poor quality and completely irrelevant. This paper tries to frame the mentioned genre, which includes various musical directions that economically bring significant benefits and help the survival of these related activities indirectly, and ultimately have a positive impact on the economy. Comparing global trends it speaks about the position of the Croatian music industry and lists the main obstacles for setting up a solid foundation for the construction of an adequate system of indexation of concert businesses that, as part of the creative industries records a meteoric economic growth.

Muddle or march: China and the 21st century Concert of Powers

Directory of Open Access Journals (Sweden)

Weizhun Mao

2014-01-01

Full Text Available Concert of Powers has emerged as an attractive modality in global governance. As an emerging power, China must seriously take this template into account. This article seeks to analyze the incentives, possibilities, and uncertainties for China to participate in Concert with reference to China's history memory on Concert, China's intellectual endeavors, as well as China's evolving foreign preferences. It concludes that China is generally qualified and capable of being a key participant in Concert of Powers with increasing willingness. Yet, China's involvement depends on 1 if Concert template can overcome its own deficiencies; 2 if Concert have competitive advantages compared with other governance alternatives for China; and 3 if China can keep its momentum on both willingness and capacity in power transition.

Concert | United Nations Orchestra at CERN | 19 September

CERN Multimedia

2014-01-01

The United Nations Orchestra will give a concert on the occasion of CERN’s 60th anniversary.   Under the baton of conductor and artistic director Antoine Marguier, the Orchestra will have the pleasure to accompany the soloist Maestro Matteo Fedeli, who, under the patronage of the Permanent Mission of Italy to the United Nations, will perform on a Stradivarius violin. The programme for the concert comprises: Jacques Offenbach, Orpheus in the Underworld Overture Franz von Suppé, Poet and Peasant Overture Camille Saint-Saëns, Introduction & Rondo Capriccioso for solo violin and orchestra Georges Bizet, Carmen Suite No. 1 Franz Lehár, Gold and Silver Waltz Gioachino Rossini, William Tell Overture   Doors open at 6 p.m. The concert will take place in a marquee behind the Globe of Science and Innovation, CERN Book your ticket here.

Gala Concert for the 50th Anniversary of CERN

CERN Multimedia

2004-01-01

The CERN 50th Anniversary celebrations will wrap up with music on 18 December with a Gala Concert by the Philharmonic Orchestra of London in Victoria Hall, Geneva. The orchestra will be directed by Tommaso Placidi, a young talented conductor, and will also enjoy the presence of Maxim Vengerov as first violin. This evening is organised by Mrs Suzanne Hurter, with the support of private companies as well as of the city and the canton of Geneva. The concert will begin with the Overture of Wagner's Flying Dutchman. Maxim Vengerov will then interpret Beethoven's Concert for violin and orchestra. The second part of the concert will be devoted to Tschaikovsky's Fourth Symphony. Tickets cost between 35CHF and 140 CHF according to the seat. People working at CERN will have a 10% discount. You may buy your tickets at the Kiosque FK inside the building Pfister Meubles in Meyrin (ch de Rianbosson 5-9) and get your discount by showing your CERN card. Find out more about the seats available, go to the Resaplus Ticket Book...

Film in concert

OpenAIRE

2017-01-01

From the very beginning of cinema, music always played an important role in the history of filmmaking. Nonetheless, film music is judged by critics as a kind of low-grade art form. However, the majority of film score composers enjoyed a classical education and composed as well for the silver screen as for the concert hall. Film music also has its roots in the musical era of romanticism. Therefore, symphonic film scores can be regarded as program music in a broader sense. These scores were inf...

Concerted and stepwise mechanisms in cycloaddition reactions: potential surfaces and isotope effects

International Nuclear Information System (INIS)

Houk, K.N.; Yi Li; Storer, Joey; Raimondi, Laura; Beno, Brett

1994-01-01

CASSCF/6-31G * calculations have been performed on concerted and stepwise Diels-Alder reactions of butadiene with ethene, the dimerization of butadiene, and the dimerization of cyclobutadiene. The relative energies of concerted and stepwise mechanisms are compared, and the factors influencing these ''energies of concert'' are discussed. The comparison of calculated isotope effects to experimental data provides support for theoretical results. (Author)

Women's Month 2006 to include a tribute concert to women composers

OpenAIRE

Lazenby, Jenna

2006-01-01

Virginia Tech will commemorate Women's Month 2006 in March with a variety of events and programs. Festivities will include a special concert to be held Wednesday, March 1 at 8 p.m. in the Squires Student Center Recital Salon. This concert will pay tribute to 400 years of women composers by featuring performances by Virginia Tech faculty, students, and guests. Admission to the concert is free, though a free-will donation will be taken to support the work of the Women's Resource Center of the N...

Teaching bioinformatics in concert.

Directory of Open Access Journals (Sweden)

Anya L Goodman

2014-11-01

Full Text Available Can biology students without programming skills solve problems that require computational solutions? They can if they learn to cooperate effectively with computer science students. The goal of the in-concert teaching approach is to introduce biology students to computational thinking by engaging them in collaborative projects structured around the software development process. Our approach emphasizes development of interdisciplinary communication and collaboration skills for both life science and computer science students.

Native Frames: Disentangling Sequential from Concerted Three-Body Fragmentation

Science.gov (United States)

Rajput, Jyoti; Severt, T.; Berry, Ben; Jochim, Bethany; Feizollah, Peyman; Kaderiya, Balram; Zohrabi, M.; Ablikim, U.; Ziaee, Farzaneh; Raju P., Kanaka; Rolles, D.; Rudenko, A.; Carnes, K. D.; Esry, B. D.; Ben-Itzhak, I.

2018-03-01

A key question concerning the three-body fragmentation of polyatomic molecules is the distinction of sequential and concerted mechanisms, i.e., the stepwise or simultaneous cleavage of bonds. Using laser-driven fragmentation of OCS into O++C++S+ and employing coincidence momentum imaging, we demonstrate a novel method that enables the clear separation of sequential and concerted breakup. The separation is accomplished by analyzing the three-body fragmentation in the native frame associated with each step and taking advantage of the rotation of the intermediate molecular fragment, CO2 + or CS2 + , before its unimolecular dissociation. This native-frame method works for any projectile (electrons, ions, or photons), provides details on each step of the sequential breakup, and enables the retrieval of the relevant spectra for sequential and concerted breakup separately. Specifically, this allows the determination of the branching ratio of all these processes in OCS3 + breakup. Moreover, we find that the first step of sequential breakup is tightly aligned along the laser polarization and identify the likely electronic states of the intermediate dication that undergo unimolecular dissociation in the second step. Finally, the separated concerted breakup spectra show clearly that the central carbon atom is preferentially ejected perpendicular to the laser field.

Concerted orientation induced unidirectional water transport through nanochannels.

Science.gov (United States)

Wan, Rongzheng; Lu, Hangjun; Li, Jinyuan; Bao, Jingdong; Hu, Jun; Fang, Haiping

2009-11-14

The dynamics of water inside nanochannels is of great importance for biological activities as well as for the design of molecular sensors, devices, and machines, particularly for sea water desalination. When confined in specially sized nanochannels, water molecules form a single-file structure with concerted dipole orientations, which collectively flip between the directions along and against the nanotube axis. In this paper, by using molecular dynamics simulations, we observed a net flux along the dipole-orientation without any application of an external electric field or external pressure difference during the time period of the particular concerted dipole orientations of the molecules along or against the nanotube axis. We found that this unique special-directional water transportation resulted from the asymmetric potential of water-water interaction along the nanochannel, which originated from the concerted dipole orientation of the water molecules that breaks the symmetry of water orientation distribution along the channel within a finite time period. This finding suggests a new mechanism for achieving high-flux water transportation, which may be useful for nanotechnology and biological applications.

Room acoustic properties of concert halls

DEFF Research Database (Denmark)

Gade, Anders Christian

1996-01-01

A large database of values of various room acoustic parameters has provided the basis for statistical analyses of how and how much the acoustic properties of concert halls are influenced by their size, shape, and absorption area (as deduced from measured reverberation time). The data have been...

Organisation syntaxique des constituants autour de l’infinitif dans les textes injonctifs : Étude de cas1

Directory of Open Access Journals (Sweden)

Khodabocus Nooreeda

2016-01-01

Full Text Available Nous proposons un travail sur l’organisation syntaxique des constituants autour d’un infinitif injonctif. En effet, l’utilisation de l’infinitif dans les injonctions nous a amené à nous interroger sur le rapport entre la tournure de la phrase et la nature du texte en question. Dans cette optique, nous proposons une étude de cas sur un corpus constitué de trois différents types de textes utilisant l’infinitif injonctif : des recettes de cuisine (Davies, 2003, Collectif, 2011, un manuel d’entretien et de maintenance des appareils de laboratoire (Organisation mondiale de la Santé, 2008 et un référentiel de compétences de secouristes (Direction de la Défense et de la Sécurité Civiles, 2007. Ces textes s’adressent à des publics différents et ont une visée propre. Dans un premier temps, nous présentons brièvement les caractéristiques linguistiques du texte injonctif en considérant les différents aspects morphosyntaxique, sémantique, pragmatique, énonciatif, la notion de sujet et les propriétés de l’infinitif injonctif comme forme verbale. Dans un second temps, nous faisons une étude sur corpus. Après avoir expliqué le choix du corpus et la construction de la base de données, nous procédons à une analyse des occurrences recueillies. Nous relevons les différentes structures syntaxiques autour de l’infinitif et nous les examinons en considérant la nature des textes où elles apparaissent. Enfin, nous soumettons une interprétation des résultats obtenus.

Practicing perfection: How concert soloists prepare for performance

Directory of Open Access Journals (Sweden)

Roger Chaffin

2006-01-01

Full Text Available Musical performances by concert soloists in the Western classical tradition are normally memorized. For memory to work reliably under the pressures of the concert stage, the performance must be practiced until it is thoroughly automatic. At the same time, the performance must be fresh and spontaneous in order to communicate emotionally with the audience. The resolution of this apparent contradiction is provided by longitudinal case studies of concert soloists preparing new works for performance. Like expert memorists in other domains, experienced musicians use highly practiced retrieval schemes to accomplish their extraordinary feats of memory. Performers have a mental map of the piece in mind as they perform that tells them where they are and what comes next - a series of landmarks, hierarchically organized by the sections and subsections of the music. The musician attends to these performance cues in order to ensure that the performance unfolds as planned. Performance cues are established by thinking about a particular feature of the music during practice so that it later comes to mind automatically. Performance cues help the soloist consciously monitor and control the rapid, automatic actions of playing, while adjusting to the needs of the moment. During practice, the musician attends mostly to basic performance cues representing critical technical features (e.g., fingerings,andinterpretive performance cues, representing phrasings, and changes in dynamics, tempo, and timbre. During performance, the musician hopes to attend mainly to expressive performance cues representing the musical feelings to be conveyed to the audience (e.g. excitement. We illustrate this analysis with a typical case study of a concert pianist learning J.S. Bach's Italian Concerto (Presto.

Interrupting the Symphony: Unpacking the Importance Placed on Classical Concert Experiences

Science.gov (United States)

Hess, Juliet

2018-01-01

The Toronto Symphony Orchestra presents a series of youth concerts each year to introduce and attract younger audiences to the symphony. Music teachers often attend these concerts with students, and the importance of such experiences is frequently emphasised and normalised. This article explores the historical roots of the following relations,…

Ethanol dehydration in HZSM-5 studied by density functional theory: evidence for a concerted process.

Science.gov (United States)

Kim, Seonah; Robichaud, David J; Beckham, Gregg T; Paton, Robert S; Nimlos, Mark R

2015-04-16

Dehydration over acidic zeolites is an important reaction class for the upgrading of biomass pyrolysis vapors to hydrocarbon fuels or to precursors for myriad chemical products. Here, we examine the dehydration of ethanol at a Brønsted acid site, T12, found in HZSM-5 using density functional theory (DFT). The geometries of both cluster and mixed quantum mechanics/molecular mechanics (QM:MM) models are prepared from the ZSM-5 crystal structure. Comparisons between these models and different DFT methods are conducted to show similar results among the models and methods used. Inclusion of the full catalyst cavity through a QM:MM approach is found to be important, since activation barriers are computed on average as 7 kcal mol(-1) lower than those obtained with a smaller cluster model. Two different pathways, concerted and stepwise, have been considered when examining dehydration and deprotonation steps. The current study shows that a concerted dehydration process is possible with a lower (4-5 kcal mol(-1)) activation barrier while previous literature studies have focused on a stepwise mechanism. Overall, this work demonstrates that fairly high activation energies (∼50 kcal mol(-1)) are required for ethanol dehydration. A concerted mechanism is favored over a stepwise mechanism because charge separation in the transition state is minimized. QM:MM approaches appear to provide superior results to cluster calculations due to a more accurate representation of charges on framework oxygen atoms.

Mutational analyses of the core domain of Avian Leukemia and Sarcoma Viruses integrase: critical residues for concerted integration and multimerization

International Nuclear Information System (INIS)

Moreau, Karen; Faure, Claudine; Violot, Sebastien; Gouet, Patrice; Verdier, Gerard; Ronfort, Corinne

2004-01-01

During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the cell DNA by the viral integrase (IN) enzyme. The central core domain of IN contains the catalytic site of the enzyme and is involved in binding viral ends and cell DNA as well as dimerization. We previously performed single amino acid substitutions in the core domain of an Avian Leukemia and Sarcoma Virus (ALSV) IN [Arch. Virol. 147 (2002) 1761]. Here, we modeled the resulting IN mutants and analyzed the ability of these mutants to mediate concerted DNA integration in an in vitro assay, and to form dimers by protein-protein cross-linking and size exclusion chromatography. The N197C mutation resulted in the inability of the mutant to perform concerted integration that was concomitant with a loss of IN dimerization. Surprisingly, mutations Q102G and A106V at the dimer interface resulted in mutants with higher efficiencies than the wild-type IN in performing two-ended concerted integration of viral DNA ends. The G139D and A195V mutants had a trend to perform one-ended DNA integration of viral ends instead of two-ended integration. More drastically, the I88L and L135G mutants preferentially mediated nonconcerted DNA integration although the proteins form dimers. Therefore, these mutations may alter the formation of IN complexes of higher molecular size than a dimer that would be required for concerted integration. This study points to the important role of core domain residues in the concerted integration of viral DNA ends as well as in the oligomerization of the enzyme

Creating personalized memories from social events: Community-based support for multi-camera recordings of school concerts

OpenAIRE

Guimaraes R.L.; Cesar P.; Bulterman D.C.A.; Zsombori V.; Kegel I.

2011-01-01

htmlabstractThe wide availability of relatively high-quality cameras makes it easy for many users to capture video fragments of social events such as concerts, sports events or community gatherings. The wide availability of simple sharing tools makes it nearly as easy to upload individual fragments to on-line video sites. Current work on video mashups focuses on the creation of a video summary based on the characteristics of individual media fragments, but it fails to address the interpersona...

Concert: Harvestehuder Kammersymphonie

CERN Multimedia

Staff Association

2017-01-01

Harvestehuder Kammersymphonie (Hamburg) Tuesday 23 May at 18.00 Main Auditorium (CERN Meyrin)   Tradition et modernité constituent le lien entre tous les musiciens de l’orchestre. La littérature orchestrale de la période classique à l’époque moderne figure régulièrement à leurs programmes. Composé de près d’une centaine d’instrumentistes de toutes professions, l'enthousiasme et la qualité musicale constituent la priorité absolue de leur activité. Après des voyages gagnant en Brésil et Angleterre, une délégation de cet ensemble est de passage dans la région. Ils sont très heureux de pouvoir donner un concert au CERN.

Music Genre as a Predictor of Resource Utilization at Outdoor Music Concerts.

Science.gov (United States)

Westrol, Michael S; Koneru, Susmith; McIntyre, Norah; Caruso, Andrew T; Arshad, Faizan H; Merlin, Mark A

2017-06-01

The aim of this study was to examine the various modern music genres and their effect on the utilization of medical resources with analysis and adjustment for potential confounders. A retrospective review of patient logs from an open-air, contemporary amphitheater over a period of 10 years was performed. Variables recorded by the medical personnel for each concert included the attendance, description of the weather, and a patient log in which nature and outcome were recorded. The primary outcomes were associations of genres with the medical usage rate (MUR). Secondary outcomes investigated were the association of confounders and the influences on the level of care provided, the transport rate, and the nature of medical complaint. A total of 2,399,864 concert attendees, of which 4,546 patients presented to venue Emergency Medical Services (EMS) during 403 concerts with an average of 11.4 patients (annual range 7.1-17.4) each concert. Of potential confounders, only the heat index ≥90°F (32.2°C) and whether the event was a festival were significant (P=.027 and .001, respectively). After adjustment, the genres with significantly increased MUR in decreasing order were: alternative rock, hip-hop/rap, modern rock, heavy metal/hard rock, and country music (Pmusic (P=.033). Alternative rock, hip-hop/rap, modern rock, heavy metal/hard rock, and country music concerts had higher levels of medical resource utilization. High heat indices and music festivals also increase the MUR. This information can assist event planners with preparation and resource utilization. Future research should focus on prospective validation of the regression equation. Westrol MS , Koneru S , McIntyre N , Caruso AT , Arshad FH , Merlin MA . Music genre as a predictor of resource utilization at outdoor music concerts. Prehosp Disaster Med. 2017;32(3):289-296.

Substance use patterns and in-hospital care of adolescents and young adults attending music concerts.

Science.gov (United States)

Ruest, Stephanie M; Stephan, Alexander M; Masiakos, Peter T; Biddinger, Paul D; Camargo, Carlos A; Kharasch, Sigmund

2018-01-09

Few studies describe medical complaints and substance use patterns related to attending music concerts. As such, the objective of this study is to describe patient demographics, substance use and intoxication patterns, and medical interventions provided to adolescents and young adults assessed in an emergency department (ED) for complaints directly related to concert attendance. A retrospective chart review of patients 13-30 years old who were transported to the ED directly from music concerts between January 2011 and December 2015 was conducted. Descriptive statistics and logistic regression were used to analyze patient demographic, intervention, and substance use data. There were 115 concerts identified, of which 48 (42%) were linked to 142 relevant ED visits; the total number of attendees at each concert is unknown. The mean age of the 142 described patients was 19.5 years (SD 3.3) with 72% pop and electronic dance music concerts was associated with the widest ranges of GCS scores (8-15 and 6-14 respectively), mass casualty incident declarations, and among the highest mean blood alcohol levels (246 and 244 mg/dL, respectively). Substance use is the predominant reason for music concert related ED visits and patients may have serious levels of intoxication, receiving multiple medical interventions. These data demonstrate the need for additional large-scale studies to confirm trends and increase awareness of this important public health problem.

Consumers’ Attitude to the Protest Against Lady Gaga’s Concert: An Exploratory Study

Directory of Open Access Journals (Sweden)

Kresno Agus Hendarto

2013-12-01

Full Text Available Lady gaga is an American singer who has won 5 Grammy Awards. In the middle of 2012, she was requested to have concert in Jakarta with the contract value of tens billion. The concert was protested by a number of groups. The promoter had approached the pressure groups and negotiated the dressing. However, Lady Gaga’s management canceled the concert for security consideration. The objectives of the study are: (1 to explore consumers’ attitude to the protest for the cancelation of Lady Gaga’s concert; and (2 using classical conditioning and expectancy-value theory, to explain consumers’ attitude to the protest. The study used focus group to collect data. The collected data was then transcribed and analyzed by content analysis. The results show that informants’ opinions can be classified into two groups: agreement and disagreement with the protest for the cancelation of Lady Gaga’s concert. Informants either agree or disagree for some reasons. Classical conditioning theory can explain either consumer’s attitude. The difference is the object of consumers’ attitude who agreed was Lady Gaga herself, while the object of disagreement was the pressure group that sponsored the protest. The attitude of the disagreement can also be explained by expectancy-value theory.

Blind Concert: The World and Its Transformation through Music

Directory of Open Access Journals (Sweden)

Nataša Milović

2015-04-01

Full Text Available This paper presents an analysis of a Blind Concert held in Belgrade. In a Blind Concert performance, the concept of “space” transforms not for the sake of transformation itself, but because of the effect it strives to achieve. This eliminates the predominance of an institution of art dictating how a musical work should be approached. Accompanying the interpretation of piano compositions, the vocalist let out screams, voices, and noises, which, one may say, could not be summoned inside us, because they have yet to be articulated. I will articulate the effects of the desired transitional forms that have remained trapped and unrepresented in social standardization in terms of Badiou’s inaesthetics.

Concerted diurnal patterns in riverine nutrient concentrations and physical conditions

International Nuclear Information System (INIS)

Scholefield, David; Le Goff, Thierry; Braven, Jim; Ebdon, Les; Long, Terry; Butler, Mark

2005-01-01

Several long-term sets of hourly nitrate concentration data were obtained through deployment of a nitrate sensor in an upper reach of the River Taw, a small moorland-fed river in the South West of the UK. Examination of the data obtained during periods of low flow and the absence of rainfall in the catchment revealed the presence of marked diurnal cycles, which were in concert and negatively correlated with diurnal cycles in water temperature. After verifying that these cycles were natural, an intensive 90-h field monitoring campaign was conducted, in which river water was sampled hourly and immediately analysed in the laboratory for molybdate-reactive phosphorus (P), nitrate, nitrite, ammonium, and pH. Coincident measurements of water temperature, river discharge and solar energy were also taken at, or close to, the site. All measurements revealed diurnal patterns and all patterns were concerted. The cycles of P, nitrate, nitrite, and discharge had two maxima and minima per 24 h, while the cycle of water temperature had one, with a maximum at 20.00 and a minimum at 08.00. The amplitudes of the cycles of P and nitrate were each about 30% of the mean values, while the amplitude of the nitrite cycle was as great as 80% of the mean value on occasions. Both biological and physical mechanisms for the cycling could operate through water temperature and/or incident radiation to account for the observed phenomenon, but there remains uncertainty of which is the more important. The observations have important implications for both the accuracy of pollution assessment in rivers and the physiological rhythms of riverine organisms

Concerted diurnal patterns in riverine nutrient concentrations and physical conditions.

Science.gov (United States)

Scholefield, David; Le Goff, Thierry; Braven, Jim; Ebdon, Les; Long, Terry; Butler, Mark

2005-05-15

Several long-term sets of hourly nitrate concentration data were obtained through deployment of a nitrate sensor in an upper reach of the River Taw, a small moorland-fed river in the South West of the UK. Examination of the data obtained during periods of low flow and the absence of rainfall in the catchment revealed the presence of marked diurnal cycles, which were in concert and negatively correlated with diurnal cycles in water temperature. After verifying that these cycles were natural, an intensive 90-h field monitoring campaign was conducted, in which river water was sampled hourly and immediately analysed in the laboratory for molybdate-reactive phosphorus (P), nitrate, nitrite, ammonium, and pH. Coincident measurements of water temperature, river discharge and solar energy were also taken at, or close to, the site. All measurements revealed diurnal patterns and all patterns were concerted. The cycles of P, nitrate, nitrite, and discharge had two maxima and minima per 24 h, while the cycle of water temperature had one, with a maximum at 20.00 and a minimum at 08.00. The amplitudes of the cycles of P and nitrate were each about 30% of the mean values, while the amplitude of the nitrite cycle was as great as 80% of the mean value on occasions. Both biological and physical mechanisms for the cycling could operate through water temperature and/or incident radiation to account for the observed phenomenon, but there remains uncertainty of which is the more important. The observations have important implications for both the accuracy of pollution assessment in rivers and the physiological rhythms of riverine organisms.

Christian rock concerts as a meeting between religion and popular culture

Directory of Open Access Journals (Sweden)

Andreas Häger

2003-01-01

Full Text Available Different forms of artistic expression play a vital role in religious practices of the most diverse traditions. One very important such expression is music. This paper deals with a contemporary form of religious music, Christian rock. Rock or popular music has been used within Christianity as a means for evangelization and worship since the end of the 1960s. The genre of "contemporary Christian music", or Christian rock, stands by definition with one foot in established institutional (in practicality often evangelical Christianity, and the other in the commercial rock musicindustry. The subject of this paper is to study how this intermediate position is manifested and negotiated in Christian rock concerts. Such a performance of Christian rock music is here assumed to be both a rock concert and a religious service. The paper will examine how this duality is expressed in practices at Christian rock concerts.

Audience noise in concert halls during musical performances

DEFF Research Database (Denmark)

Jeong, Cheol-Ho; Marie, Pierre; Brunskog, Jonas

2012-01-01

functions of the sound pressure levels were obtained in octave bands, which were fitted with three Gaussian distribution curves. The Gaussian distribution curve with the lowest mean value corresponds to a mixture of the technical background noise and audience generated noise, which is named the mixed...... background noise. Finally, the audience noise distribution is extracted by energy subtraction of the technical background noise levels measured in an empty condition from the mixed background noise levels. As a single index, L-90 of the audience noise distribution is named the audience noise level. Empirical...... prediction models were made using the four orchestra concert halls, revealing that the audience noise level is significantly correlated with the technical background noise level. It is therefore concluded that a relaxation of the current background noise recommendations for concert halls is not recommended...

Audience noise in concert halls during musical performances

DEFF Research Database (Denmark)

Marie, Pierre; Jeong, Cheol-Ho; Brunskog, Jonas

2012-01-01

functions of the sound pressure levels were obtained in octave bands, which were fitted with three Gaussian distribution curves. The Gaussian distribution curve with the lowest mean value corresponds to a mixture of the technical background noise and audience generated noise, which is named the mixed...... background noise. Finally, the audience noise distribution is extracted by energy subtraction of the technical background noise levels measured in an empty condition from the mixed background noise levels. As a single index, L90 of the audience noise distribution is named the audience noise level. Empirical...... prediction models were made using the four orchestra concert halls, revealing that the audience noise level is significantly correlated with the technical background noise level. It is therefore concluded that a relaxation of the current background noise recommendations for concert halls is not recommended....

[Public music concerts in a psychiatric hospital: effects on public opinion and as therapy for patients].

Science.gov (United States)

Takasaka, Y; Yokota, O; Tanioka, T; Nagata, K; Yasuoka, K; Toda, H

2001-01-01

We investigate the effects of music therapy concerts, which were held 60 times over a four year period, 1992 to 1996, in Geiyo Psychiatric Hospital, Kochi Prefecture and found that; 1) Musicians who performed at the concerts were not only from Kochi prefecture but also from other prefectures (10 times) and from four foreign countries (7 times). 2) Live concerts in a small hall had a positive influence on patients and drew the patient's attention and interest away from their hallucinations and delusions to the real world. Moreover, the concerts provided the patients with chances to acquire social graces such as being well-groomed. 3) Explanations by the musicians, interviews with the musicians and the seasonal choruses accompanied by the musicians were helpful to give the patients motives for recovering communication skills and to interact with society. 4) Inquiries to the patients about the concerts indicated discrepancies between the poor observed estimations during the concerts (83.3%) and the good subjective impressions expressed by the patients (82.0%), suggesting that the patients were not good at expressing their internal emotions through facial expressions or attitudes. 5) Many citizens including children came to the concerts and/or gave aid to the hospital because the concerts were open to the public and we suggest that this contributed to improving the general publics' image of psychiatric hospitals. Questionnaires revealed that 90% of people in a control group had a bad image of psychiatric hospitals in Japan, but only 32% of the members of the general public who attended our concerts had a bad image of psychiatric hospitals. In addition, the revolving ratio of the hospital beds rose from 0.4 to 1.2 over the four years, which also suggests a beneficial effect on the patients.

Sound Design in Virtual Reality Concert Experiences using a Wave Field Synthesis Approach

DEFF Research Database (Denmark)

Lind, Rasmus Bloustrød; Milesen, Victor; Smed, Dina Madsen

2017-01-01

In this paper we propose an experiment that evaluates the influence of audience noise on the feeling of presence and the perceived quality in a virtual reality concert experience delivered using Wave Field Synthesis. A 360 degree video of a live rock concert from a local band was recorded. Single...

Non-concerted ITS evolution in Mammillaria (Cactaceae).

Science.gov (United States)

Harpke, Doerte; Peterson, Angela

2006-12-01

Molecular studies of 21 species of the large Cactaceae genus Mammillaria representing a variety of intrageneric taxonomic levels revealed a high degree of intra-individual polymorphism of the internal transcribed spacer region (ITS1, 5.8S rDNA, ITS2). Only a few of these ITS copies belong to apparently functional genes, whereas most are probably non-functional (pseudogenes). As a multiple gene family, the ITS region is subjected to concerted evolution. However, the high degree of intra-individual polymorphism of up to 36% in ITS1 and up to 35% in ITS2 suggests a non-concerted evolution of these loci in Mammillaria. Conserved angiosperm motifs of ITS1 and ITS2 were compared between genomic and cDNA ITS clones of Mammillaria. Some of these motifs (e.g., ITS1 motif 1, 'TGGT' within ITS2) in combination with the determination of GC-content, length comparisons of the spacers and ITS2 secondary structure (helices II and III) are helpful in the identification of pseudogene rDNA regions.

“The Concert of Europe” In 20th Century British and American Historiography

Directory of Open Access Journals (Sweden)

Ekaterina V. Romanova

2016-01-01

Full Text Available The article provides a critical analysis of the interpretations of the Concert of Europe by British and American historians of the XXth century. The interest in the study of this phenomenon is rooted in its relation to the problems of the maintenance of international order and stability. It is not only academic, being partly determined by the fact that throughout the XX century first Britain and then the USA was at the top of the world hierarchy, and accordingly played a leading role in the construction and maintenance of the European order. Current international environment, the experience of the two World Wars of the XXth century determined the angle from which the phenomenon of the Concert of Europe was studied. Whereas in the second half of the 1910s - early 1920s historians pointed to the deficiencies of the international system of the preceding century (and in particular, the institution of the Concert of Europe, the students of the Vienna system working after the Second World War regarded the period of 1815-1914 as relatively stable, compared to the short interwar interlude. The Concert of Europe was named as one of the factors contributing to stability and peace. Certain logic can be discerned in the development of the historiography of the problem, which to some degree reflected the evolution of ideas about international relations management. At the same time, the differences in the interpretations of the Concert of Europe derive from the fact that this very concept in the XIXth century was not fixed and static. Great Powers' readiness to cooperation did not mean that there were no conflicts of interests. They struggled for leadership within the Concert and sought to impart to it their own interpretation.

Standing Concertation Committee

CERN Document Server

HR Department

2008-01-01

ORDINARY MEETING ON 27 FEBRUARY 2008 The main items discussed at the meetings of the Standing Concertation Committee on 27 February 2008 included: Short-term Saved Leave Scheme The Committee noted that, by the end of February 2008, some 600 staff had enrolled in the short-term saved leave scheme: approx. 58% had signed up for 1 slice, 14% for two slices, 5% for three slices and 23% for four slices. Administrative Circular No. 4 (Rev. 4) - Unemployment Insurance Scheme The Committee agreed to recommend the Director-General to approve Administrative Circular No. 4 (Rev. 4) - Unemployment Insurance Scheme. Administrative Circular No. 30 (Rev. 2) - Financial benefits upon taking up appointment and termination of contract The Committee agreed to recommend the Director-General to approve Administrative Circular No. 30 (Rev. 2) - Financial Benefits upon taking up appointment and termination of contract. Progressive Retirement Programme The Progressive Retirement Programme (PR...

Concert Viewing Headphones

Directory of Open Access Journals (Sweden)

Kazuya Atsuta

2011-01-01

Full Text Available An audiovisual interface equipped with a projector, an inclina-tion sensor, and a distance sensor for zoom control has been developed that enables a user to selectively view and listen to specific performers in a video-taped group performance. Dubbed Concert Viewing Headphones, it has both image and sound processing functions. The image processing extracts the portion of the image indicated by the user and projects it free of distortion on the front and side walls. The sound processing creates imaginary microphones for those performers without one so that the user can hear the sound from any performer. Testing using images and sounds captured using a fisheye-lens camera and 37 lavalier microphones showed that sound locali-zation was fastest when an inverse square function was used for the sound mixing and that the zoom function was useful for locating the desired sound performance.

Exploring the impact of music concerts in promoting well-being in dementia care.

Science.gov (United States)

Shibazaki, Kagari; Marshall, Nigel A

2017-05-01

This study explores the specific effects of live music concerts on the clients with dementia, their families and nursing staff/caregivers. Researchers attended 22 concerts in care facilities in England and Japan. Interviews were carried out with clients with dementia, nursing staff and family members. Observations were also carried out before, during and after the concerts. All observations were recorded in field notes. The effect of the concerts in both countries was seen to be beneficial to all clients and nursing staff, whether or not they attended the concert. Interviews with clients with mild to mid-stage dementia noted increased levels of cooperation, interaction and conversation. Those with more advanced forms of dementia exhibited decreased levels of agitation and anti-social behaviour. Staff members reported increased levels of care, cooperation and opportunities for assessment. Family members noted an increase in the levels of well-being in their partner/parent as well as in themselves. The study also suggested that the knowledge of musical components, an awareness of the rules of music and specific musical preferences appear to remain well beyond the time when other cognitive skills and abilities have disappeared. This initial study provided some further indication in terms of the uses of music as a non-pharmacological intervention for those living with all stages of dementia. These included opportunities for assessment of physical abilities as well as facilitating an increasing level of care.

Health survey on cancers about the Tricastin nuclear site; Etude sanitaire sur les cancers autour du site nucleaire du Tricastin

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-07-01

This survey aims at describing the health status of the population around the Tricastin site, and more particularly at determining whether there is a difference between death or cancer occurrence frequencies observed around this site with respect to reference frequencies. It does not aim at assessing the health impact of the site industrial installations. Cancer mortality data, cancer diagnosis data, demographic data, child cancer data, data related to hospital stays in relationship with cancer, long duration hospital stay data, and mortality data are used. Several indicators are defined and used: standardised mortality ratio, standardised hospitalisation ratio. Data are also analysed in terms of location, and socio-demographic categories. It appears that there is no specific health situation for the considered area, except for pancreas cancer for women

Concerted action on the retrievability of long lived radioactive waste in deep underground repositories - progress to date

International Nuclear Information System (INIS)

Dodd, D.H.

2000-01-01

Within the EURATOM Framework Programme: Nuclear Fission Safety, a Concerted Action on the retrievability of long lived radioactive waste in deep underground repositories is being carried out. This Concerted Action commenced on the 1st of January 1998 and involves experts from nine different European countries. The Concerted Action will be completed by the 31st of December 1999. This paper gives a brief overview of the objectives of the Concerted Action, the work programme that has been defined to meet these objectives, the work performed to date, and the remaining work programme. (author)

Standing Concertation Committee

CERN Multimedia

HR Department

2009-01-01

The main items discussed at the meetings of the Standing Concertation Committee in the first quarter of 2009 included: Merit Appraisal and Recognition Scheme (MARS) 2009 exercise The committee took note of 2009 MARS ceiling guidelines giving the advancement budget by career path and amounting to approx 1.80% of the basic salary bill. To this will be added 250 steps CERN-wide, financed by savings from implementation of the international indemnity for 2007, 2008 and the first half of 2009. The specific Senior Staff Guidelines, including the proposed number of promotions from Career Path E to F, were also noted. The guidelines with respect to step distribution were also noted: the minima and maxima remain the same as in previous years. Compliance with the guidelines will continue to be monitored closely (more details, including a frequently asked questions section). It was also noted that Financial Awards (awards for extraordinary service and responsibility allowances) may b...

Standing Concertation Committee

CERN Multimedia

2007-01-01

Ordinary meeting on 30 January 2007 The main items discussed at the meeting of the Standing Concertation Committee on 30 January 2007 included: Administrative Circular No. 26: with the introduction of the merit recognition system in the framework of the 5-yearly review of CERN employment conditions, Administrative Circular No. 26 has been revised. The committee took note of the revised document which is being finalized for submission to the Director-General for approval in the near future. Technical analysis of CERN Health Insurance Scheme: the Committee was informed that a group has been set up by the Director-General to analyse the financial situation of the CERN Health Insurance Scheme in the short and long term, and to propose measures to ensure that the Scheme remains in financial balance, with adequate cover, over the medium term. The group's terms of reference and membership were communicated. Voluntary programmes It was announced that the programmes: 'part-time work as a pre-retirement measure...

Standing Concertation Committee

CERN Multimedia

2007-01-01

ORDINARY MEETING ON 30 JANUARY 2007 The main items discussed at the meeting of the Standing Concertation Committee on 30 January 2007 included: Administrative Circular No. 26: with the introduction of the merit recognition system in the framework of the 5-yearly review of CERN employment conditions, Administrative Circular No. 26 has been revised. The Committee took note of the revised document which is being finalized for submission to the Director-General for approval in the near future. Technical analysis of CERN Health Insurance Scheme: the Committee was informed that a group has been set up by the Director-General to analyse the financial situation of the CERN Health Insurance Scheme in the short and long term, and to propose measures to ensure that the Scheme remains in financial balance, with adequate cover, over the medium term. The group's terms of reference and membership were communicated. Voluntary programmes It was announced that the programmes: 'part-time work as a pre-retirement mea...

Standing Concertation Committee

CERN Multimedia

HR Department

2009-01-01

Ordinary Meeting on 11 May 2009 The meeting of the Standing Concertation Committee held on 11 May 2009 was entirely dedicated to the preparation of the TREF meeting on 19 & 20 May 2009. The Committee took note, discussed and agreed on some clarifications on a number of documents and presentations that the Management planned to submit and/or present to TREF on the following subjects: • Personnel statistics 2008: J. Purvis presented the Personnel Statistics for 2008 prepared by HR Department. In line with the previous year, key messages were firstly, a general reduction in staff (2544 to 2400, - 6%), secondly, a reduction in administrative services personnel (from 422 to 387, - 8%) and thirdly, a marked increase in the number of Users and Unpaid Associates (from 8369 to 9140, + 9%) • Five-Yearly Review 2010: A series of draft documents were submitted for discussion, comprising an introductory document explaining the statutory basis for the following four document...

Standing Concertation Committee

CERN Document Server

HR Department

2010-01-01

Main issues examined at the meeting of 2 October 2009 The October 2009 meeting of the Standing Concertation Committee was entirely devoted to preparation of TREF’s meeting on 21-22 October. The Committee took note of, discussed and agreed on clarifications needed to some of the documents and presentations that the Management intended to submit and/or present to TREF on the following subjects: Equal opportunities The Committee took note of a preliminary report on equal opportunities at CERN drawn up by D. Chromek-Burckhart, the Equal Opportunities Officer, and T. Smith, Chairman of the Equal Opportunities Advisory Panel, containing in particular a proposal for a new process for resolving harassment conflicts. Technical analysis of the CERN Health Insurance Scheme - Actuary’s Report The Committee took note of a presentation by P. Charpentier, Chairman of the CERN Health Insurance Supervisory Board (CHIS Board), on the 2009 actuarial report on the CERN Health Insurance Scheme (CHIS). Th...

Standing Concertation Commmittee

CERN Multimedia

HR Department

2007-01-01

Ordinary meeting on 27 February 2007 The main items discussed at the meeting of the Standing Concertation Committee on 27 February 2007 included: Saved Leave Scheme (SLS): It was announced that a Management/Staff Association working group had been set up to discuss the Saved Leave Scheme (SLS): Members: M. Büttner, E. Chiaveri (chair), Ph. Defert, D. Klem, M. Vitasse, J.-M. Saint-Viteux. It was noted that the Staff Association was launching a questionnaire on SLS and distributed to all members of the personnel. Merit Recognition Guidelines : in the context of the new Merit Appraisal and Recognition Scheme (MARS), the committee took note of the CERN-wide 2007 Merit Recognition Guidelines, including the Frequently Asked Questions on HR Department's dedicated website. Information on CERN's medium and long-term plans (MTP-LTP)/Contract renewals/ External mobility The Committee took note of the information provided on CERN's MTP-LTP and of documentation distributed at the meeting by the Staff Associatio...

Standing Concertation Committee

CERN Document Server

HR Department

2007-01-01

ORDINARY MEETING ON 27 FEBRUARY 2007 The main items discussed at the meeting of the Standing Concertation Committee on 27 February 2007 included: Saved Leave Scheme (SLS): It was announced that a Management/Staff Association working group had been set up to discuss the Saved Leave Scheme (SLS): Members : M. Büttner, E. Chiaveri (chair), Ph. Defert, D. Klem, M. Vitasse, J.-M. Saint-Viteux. It was noted that the Staff Association was launching a questionnaire on SLS and distributed to all members of the personnel. Merit Recognition Guidelines: In the context of the new Merit Appraisal and Recognition Scheme (MARS), the committee took note of the CERN-wide 2007 Merit Recognition Guidelines, including the Frequently Asked Questions on HR Department's dedicated website. Information on CERN's medium and long-term plans (MTP-LTP)/Contract renewals/ External mobility The Committee took note of the information provided on CERN's MTP-LTP and of documentation distributed at the meeting by the Staff ...

Standing Concertation Commmittee

CERN Document Server

HR Department

2007-01-01

Ordinary meeting on 2 november 2007 Extraordinary meeting on 12 November 2007 The main items discussed at the meetings of the Standing Concertation Committee on 2 November 2007 and 12 November included: Restaurants Supervisory Committee Report The committee took note of the report by the chairman of the Restaurants Supervisory Committee (RSC), T. Lagrange. In particular, it was recorded that, in Restaurant No. 1, the new kitchen and free flow arrangements had been inaugurated and all works had been commissioned on schedule in October 2007.The contractor, Novae, had taken over maintenance of the new kitchen. Some price increases were to be expected in the coming months due mainly to strong increases in the cost of basic ingredients. A problem with bad smells in the area of Restaurant No. 1 was being taken care of by tuning the ventilation system. The RSC wished to thank the management and staff of Restaurant No. 2 for their cooperation while Restaurant No 1 was ...

STANDING CONCERTATION COMMMITTEE

CERN Multimedia

HR Department

2008-01-01

ORDINARY MEETING ON 27 FEBRUARY 2008 The main items discussed at the meetings of the Standing Concertation Committee on 27 February 2008 included: Short-term Saved Leave Scheme The committee noted that, by the end of February 2008, some 600 staff had subscribed to the short-term saved leave scheme: approx 58% had subscribed 1 slice, 14% two slices, 5% three slices and 23% four slices. Administrative Circular No. 4 (Rev. 4) - Unemployment Insurance Scheme The committee agreed to recommend Administrative Circular No. 4 (Rev. 4) - Unemployment Insurance Scheme to the Director-General for approval. Administrative Circular No. 30 (Rev. 2) - Financial benefits upon taking up appointment and termination of contract The committee agreed to recommend Administrative Circular No. 30 (Rev. 2) - Financial Benefits upon taking up appointment and termination of contract to the Director-General for approval. Progressive Retirement Programme The Progressive Retirement Programme (PRP) was extended for a further year to 3...

Trends in preference, programming and design of concert halls for symphonic music

DEFF Research Database (Denmark)

Gade, Anders Christian

2008-01-01

This paper discusses the evolution in taste regarding concert hall acoustics and how this can be reflected in the new halls being built today. The clients' and listener's preferences are not only based on listening in existing halls; but also on listening to reproduced music recorded with microph......This paper discusses the evolution in taste regarding concert hall acoustics and how this can be reflected in the new halls being built today. The clients' and listener's preferences are not only based on listening in existing halls; but also on listening to reproduced music recorded...

STANDING CONCERTATION COMMITTEE

CERN Multimedia

2003-01-01

ORDINARY MEETING ON 29 SEPTEMBER 2003 Original: English This meeting was devoted to the main topics summarised below. 1 Follow-up from the meetings of TREF and the Finance Committee in September 2003 The last meeting of TREF had been devoted to presentations and clarifications on the 5-Yearly Review process. The content and planning of the 2005 Review are matters for the next Management, which will be presented to TREF next year. Underlining that due account has to be taken of the limited resources available to conduct such an exercise, the Staff Association stated that it looks forward to the concertation process at the SCC in preparing the next 5-Yearly Review to define an optimum set of topics in order to ensure that CERN can attract, retain and motivate the personnel that it needs to remain a centre of excellence. The Chairman of the SCC recalled that an information document on the Cost-Variation Index for 2004 had been transmitted to the Finance Committee last September and that complete information o...

Standing concertation commmittee

CERN Multimedia

HR Department

2009-01-01

MEETINGS ON 2 AND 9 DECEMBER 2008 The main items discussed at the meetings of the Standing Concertation Committee on 2 and 9 December 2008 included: Medical Service Report 2007 The Committee took note of the report by Dr. E. Reymond (see http://sc-me.web.cern.ch/sc-me/fr/indexFR.htm) and of a number of points raised during the discussion. It was noted that the number of professional accidents declined in 2007 (361 accidents) in comparison with 2006 (483), as well as their gravity and frequency. The CERN Medical Service carried out a study on cancer prevalence (number of cases) and incidence (new cases per year per 100000 people), between 1993 and 2007, which identified some prostate, breast and colorectal cancers, though less than in the two Host States. Specific preventive actions will be promoted by the CERN CHISboard and the Medical Service in this context as well as in other areas. The committee expressed its thanks to all members of the Medical Service for their work i...

Parenting Priorities and Pressures: Furthering Understanding of "Concerted Cultivation"

Science.gov (United States)

Vincent, Carol; Maxwell, Claire

2016-01-01

This paper re-examines the purposes of a planned and intentional parenting style--"concerted cultivation"--for different middle-class groups, highlighting that social class fraction, ethnicity, and also individual family disposition, guides understandings of the purposes of enrolling children in particular enrichment activities. We…

CONCERT-'European Joint Programme for the Integration at Radiation Protection Research'; CONCERT-''European Joint Programme for the Integration at Radiation Protection Research''

Energy Technology Data Exchange (ETDEWEB)

Birschwilks, Mandy; Schmitt-Hannig, Annemarie [Bundesamt fuer Strahlenschutz, Oberschleissheim (Germany). Internationale und Nationale Zusammenarbeit im Strahlenschutz; Jung, Thomas [Bundesamt fuer Strahlenschutz, Oberschleissheim (Germany). Strahlenschutz und Gesundheit

2016-08-01

In 2009 the High Level Expert Group (HLEG) on low dose research recommended the development of a scientific platform for low dose radiation research. The foundation of MELODI (Multidisciplinary European Low Dose Initiative) occurred in 2010. In 2015 a new project on radiation protection research was established: CONCERT (European Joint Programme for the Integration at Radiation Protection Research). The aim is the coordination of the already existing scientific platforms MELODI (radiation effects and interactions), ALLIANCE (radioecology), NERIS (nuclear and radiological emergency protection) and EURADOS (radiation dosimetry). With CONCERT an efficient use of this infrastructure for research cooperation and transparency is intended.

Standing Concertation Committee: Ordinary Meeting on 1 September 2004

CERN Document Server

2004-01-01

Original: English This meeting was devoted to the main topics summarised below. Preparation for the 5-Yearly Review 2005 The Committee took note that preparatory work had started over the summer months on various topics for the 5-Yearly Review, in line with the internal planning presented to the SCC last June. Concertation process and working procedures Referring to its recent publications, the Staff Association raised this subject in connection with the organization and procedures of the HR study teams and CFO discussion group working on the various topics which are to be covered in the 5-Yearly Review. After some debate, both the Management and the Staff Association underlined the importance that they attach to an efficient concertation process. Both parties agreed to continue the discussion after the meeting. Data collection questionnaire The SCC discussed the content of the questionnaire for the data collection enquiry to be launched this autumn. Subject to some further clarifications and improv...

STANDING CONCERTATION COMMITTEE: ORDINARY MEETING ON 5 FEBRUARY 2004

CERN Multimedia

2004-01-01

Original : English This meeting was devoted to the main topics summarised below. 1-The internal concertation process Responding to various questions in this connection raised by the Staff Association, the Chairman stated that the Management wishes to diminish in no way the role of the SCC in the internal concertation process, as set out in chapter VII of the Staff Rules and Regulations. On the contrary, he underlined the importance of ensuring this process to debate strategic issues concerning employment conditions, prior to decisions taken by the Director-General. On a point of clarification, he confirmed that, as discussed at the January meeting of the Executive Board, the Management wishes to abolish the Long-Term Contract Board and the Senior Staff Advancement Committee; the SCC took note of this intention. Simplified procedures without the Committees would be presented as soon as possible to the SCC, together with amendments to the relevant Administrative Circulars. 2-MAPS The Committee discussed th...

Acts of the Ville d'Avray seminar on the 21. and 22. of january 2003 on the dialogue around industrial sites; Actes du seminaire de Ville d'Avray des 21 et 22 janvier 2003 sur la concertation autour des sites industriels

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-01-15

Following the research work on the stakes of the social dialogue around the follow up of nuclear and non nuclear industrial installations opened by I.R.S.N. in 2000, a seminar has been organised on the 21. and 22. of january 2003 at Ville d' Avray. This seminar gathered different personalities( administration, experts, operators, associations, information local commissions, elected) in order to discuss and enrich the conclusions of the research work and elaborate a contribution about the dialogue process. The different subjects tackled were: Approach concerning the release of the british nuclear fuel installation at Sellafield, nuclear power plants of Saint Alban and Cogema La Hague, industrial site of Metaleurop at Noyelles-Godault, local commission of surveillance of the nuclear site of power generation of Fessenheim, evolution of the legislation frame around installations. (N.C.)

Outreach for Families and Girls- Astronomy at Outdoor Concerts and at Super Bowl or Halloween Star Parties

Science.gov (United States)

Lubowich, Donald A.

2011-05-01

Bring telescope to where the people are! Music and Astronomy Under the Stars (MAUS) is a NASA-funded as astronomy outreach program at community parks and music festivals (1000 - 25,000 people/event). While there have been many astronomy outreach activities and telescope observations at sidewalks and parks, this program targets a different audience - music lovers who are attending concerts in community parks or festivals. These music lovers who may not have visited science museums, planetariums, or star parties are exposed to telescope observations and astronomy information with no additional travel costs. MAUS includes solar observing, telescope observations including a live imaging system, an astronomical video, astronomy banners/posters, and hands-on activities. MAUS increased awareness, engagement, and interest in astronomy at classical, pop, rock, and ethnic music concerts. Since 2009 over 50,000 people have participated in these outreach activities including a significant number of families and young girls. In addition to concerts in local Long Island parks, there were MUAS events at Tanglewood (summer home of the Boston Symphony Orchestra), Jazz in Central Park, and Astronomy Night on the National Mall (co-sponsored by the White House Office of Science and Technology Policy). In 2011 MUAS will be expanded to include Ravinia (summer home of the Chicago Symphony Orchestra), the Newport Folk Festival, and the Bethel Woods Center for the Arts (site of the 1969 Woodstock festival). According to our survey results, music lovers became more informed about astronomy. Expanding Hofstra University's successful outreach programs, I propose the creation of a National Halloween Stars event targeting children and a National Super Bowl Star Party targeting girls, women, and the 2/3 of Americans who do not watch the Super Bowl. This can be combined with astronomers or amateur astronomers bringing telescopes to Super Bowl parties for football fans to stargaze during

Exposure and materiality of the secondary room and its impact on the impulse response of coupled-volume concert halls

Science.gov (United States)

Ermann, Michael; Johnson, Marty

2005-06-01

How does sound decay when one room is partially exposed to another (acoustically coupled)? More specifically, this research aims to quantify how operational and design decisions impact sound fields in the design of concert halls with acoustical coupling. By adding a second room to a concert hall, and designing doors to control the sonic transparency between the two rooms, designers can create a new, coupled acoustic. Concert halls use coupling to achieve a variable, longer, and distinct reverberant quality for their musicians and listeners. For this study a coupled-volume shoebox concert hall is conceived with a fixed geometric volume, form, and primary-room sound absorption. Aperture size and secondary-room sound absorption levels are established as variables. Statistical analysis of sound decay in this simulated hall suggests a highly sensitive relationship between the double-sloped condition and (1) architectural composition, as defined by the aperture size exposing the chamber and (2) materiality, as defined by the sound absorptance in the coupled volume. The theoretical, mathematical predictions are compared with coupled-volume concert hall field measurements and guidelines are suggested for future designs of coupled-volume concert halls.

Choeur du CERN : Concert

CERN Multimedia

CERN Choir

2017-01-01

Une œuvre à découvrir! La grande Missa pro defunctis de François-Joseph Gossec (1734-1829) est le chef-d’œuvre tôt venu (à vingt-cinq ans) d’un compositeur qui vivra encore 70 ans après sa création. Elle a connu la gloire, puis s’est fait un peu oublier. Pas du tout le monde cependant : des musicologues ont montré ce que le Requiem de Mozart lui devait ; et il suffit de l’avoir entendue pour comprendre pourquoi Berlioz (qui avait vingt-six ans à la mort de Gossec) en a été impressionné : les nombreux cuivres et bois répartis dans des endroits plus ou moins cachés de la salle de concert pour exprimer les frayeurs du Jugement dernier annoncent son Requiem – et celui de Verdi. Mais « plus encore que par...

THE ORIGIN OF CONCERT MUSIC IN NIGERIA, 1850 - 1920 ...

African Journals Online (AJOL)

Mitch

Studies on the origins of concert music in Nigeria often dwell on aspects of the ... chronicle its development from its earliest beginnings to the present. ... their children, trying to live as much as possible like Victoria gentlemen.' (Ajayi .... entertainment began in 1822 the movement for a public hall that bore fruit in the building.

Interactive painting. An evolving study to facilitate reduced exclusion from classical music concerts for the deaf community

DEFF Research Database (Denmark)

Brooks, Tony

2005-01-01

Exclusion from the joy of experiencing music, especially in concert venues, is especially applicable to those with an auditory impairment. There have been limited investigations into how to reduce the exclusion for this community in attending classical orchestra music concerts. Through utilizing ...

The impact of local government cultural policies on the sales of tickets for private music concerts in Japan

OpenAIRE

谷口, みゆき

2014-01-01

This paper attempts to examine the effect of public cultural policy on the sales of tickets for private music concerts in Japan. In particular, it focuses on how the introduction of the Designated Manager System (DMS) in 2006 influenced the sales of tickets for private music concerts. The hypothesis that both local governments' cultural investments and the DMS have increased the sales of tickets for private music concerts is examined. Data from the Private Music Live Entertainment 2000-2008 i...

An Interactive Concert Program Based on Infrared Watermark and Audio Synthesis

Science.gov (United States)

Wang, Hsi-Chun; Lee, Wen-Pin Hope; Liang, Feng-Ju

The objective of this research is to propose a video/audio system which allows the user to listen the typical music notes in the concert program under infrared detection. The system synthesizes audio with different pitches and tempi in accordance with the encoded data in a 2-D barcode embedded in the infrared watermark. The digital halftoning technique has been used to fabricate the infrared watermark composed of halftone dots by both amplitude modulation (AM) and frequency modulation (FM). The results show that this interactive system successfully recognizes the barcode and synthesizes audio under infrared detection of a concert program which is also valid for human observation of the contents. This interactive video/audio system has greatly expanded the capability of the printout paper to audio display and also has many potential value-added applications.

Electronic Performance Monitoring: An Organizational Justice and Concertive Control Perspective.

Science.gov (United States)

Alder, G. Stoney; Tompkins, Phillip K.

1997-01-01

Applies theories of organizational justice/concertive control to account for contradictions inherent in electronic monitoring of workers by organizations. Argues that results are usually positive when workers are involved in the design and implementation of monitoring systems, and monitoring is restricted to performance-related activities with…

CONCERT. ''European joint programme for the integration of radiation protection research''; CONCERT. Gemeinsame Europaeische Forschungsfoerderung

Energy Technology Data Exchange (ETDEWEB)

Schmitt-Hannig, A.; Birschwilks, M.; Jung, T. [Bundesamt fuer Strahlenschutz (Germany)

2016-07-01

CONCERT is a joint project of the EU and its member states which assume joint financing: Over the next five years the largest European radiation protection programme so far will have available about 28 Million Euros for research and integrative measures, whereby the European Commission will bear 70 per cent of the costs. Integrative measures include, among others, targeted vocational education and training of junior researchers in radiation protection, better access to research and irradiation facilities for scientists, as well as a stronger connection of universities and research centres in radiation protection research.

Information concerning the results of the concerted work stoppage on 22 June 2011 (from 8-30 to 12-30)

CERN Multimedia

Human Resources Department

2011-01-01

 Following the concerted work stoppage called by the Staff Association for 22 June 2011 concerning the measures aimed at restoring the financial equilibrium of the Pension Fund, HR Department invited staff members and fellows to declare whether or not they had participated in this action. As indicated in the communication sent to the persons concerned, it was assumed that those who did not complete the electronic declaration form did not take part in the work stoppage. The results are as follows:     Staff and fellows Declarations: Yes (took part in the concerted work stoppage) 373 Declarations: No (did not take part in the concerted work stoppage) 386 Those requisitioned 120 Those not able to participate in the concerted work stoppage (leave, absence, training…) ...

Tightening the Iron Cage: Concertive Control in Self-Managing Teams.

Science.gov (United States)

Barker, James R.

1993-01-01

Describes how an (industrial) organization's control system evolved in response to a managerial change from hierarchical, bureaucratic control to concertive control via self-management teams. The organization's members developed a system of value-based normative rules that controlled their actions more powerfully and completely than did the former…

The European concerted action on air pollution epidemiology

Energy Technology Data Exchange (ETDEWEB)

Ackermann-Liebrich, U. [Basel Univ. (Switzerland). Inst. for Social and Preventive Medicine

1995-12-31

The European Concerted Action on Air Pollution Epidemiology was started in 1990 with the aim of bringing together European researchers in the field and improving research through collaboration and by preparing documents which would help to this end and by organizing workshops. A further aim was to stimulate cooperative research. Air pollution epidemiology investigates human effects of community air pollution by epidemiological methods. Epidemiology in general investigates the distribution and determinants of health-related states and events in populations. Diseases in which air pollution may play a significant role are mainly diseases of the respiratory system, for example chronic non-specific lung disease and lung cancer. Most diseases caused by air pollution can also be caused by other factors. Air pollution epidemiology is therefore specific in the expo variable (community air pollution) rather than in the type of health effects being studied. Air pollution epidemiology is beset with some specially challenging difficulties: ubiquitous exposure and as a consequence limited heterogeneity in exposure, low relative risks, few or specific health end points, and strong confounding. Further on the exposure-effect relationship is complicated by assumptions inherent to different study designs which relate to the exposure duration necessary to produce a certain health effect. In reports and workshops the concerted action tries to propose strategies to deal with these problems. (author)

The European concerted action on air pollution epidemiology

Energy Technology Data Exchange (ETDEWEB)

Ackermann-Liebrich, U [Basel Univ. (Switzerland). Inst. for Social and Preventive Medicine

1996-12-31

The European Concerted Action on Air Pollution Epidemiology was started in 1990 with the aim of bringing together European researchers in the field and improving research through collaboration and by preparing documents which would help to this end and by organizing workshops. A further aim was to stimulate cooperative research. Air pollution epidemiology investigates human effects of community air pollution by epidemiological methods. Epidemiology in general investigates the distribution and determinants of health-related states and events in populations. Diseases in which air pollution may play a significant role are mainly diseases of the respiratory system, for example chronic non-specific lung disease and lung cancer. Most diseases caused by air pollution can also be caused by other factors. Air pollution epidemiology is therefore specific in the expo variable (community air pollution) rather than in the type of health effects being studied. Air pollution epidemiology is beset with some specially challenging difficulties: ubiquitous exposure and as a consequence limited heterogeneity in exposure, low relative risks, few or specific health end points, and strong confounding. Further on the exposure-effect relationship is complicated by assumptions inherent to different study designs which relate to the exposure duration necessary to produce a certain health effect. In reports and workshops the concerted action tries to propose strategies to deal with these problems. (author)

Concerted Cultivation and Music Learning: Global Issues and Local Variations

Science.gov (United States)

Ilari, Beatriz

2013-01-01

"Concerted cultivation" has been described as a common, urban middle-class practice concerning the enrollment of children in a variety of age-specific activities that may promote the learning of valuable life skills as well as the development of individual abilities (Lareau, 2003). Music is one such activity. This study investigated the…

Family Music Concerts: Bringing Families, Music Students, and Music Together

Science.gov (United States)

Kenney, Susan Hobson

2014-01-01

This article describes how conductors of the top performing groups and music education faculty at one university collaborated to create a Family Concert Series for parents and children of all ages, including infants in arms. Recognizing the conflict between "The first three years of life are the most important for educating a young child in…

Statistics regarding the concerted work stoppage of 28 April 2006

CERN Multimedia

HR Department

2006-01-01

Following the concerted work stoppage of Friday, 28 April, HR Department sent out a questionnaire to all staff members in order to determine the number of those who participated. Questionnaires sent out : 2665 Staff members asked not to return the questionnaire: (on official duty/special leave/sick leave/annual leave) -1006 of which, those who took one day only of annual leave linked to the weekend of 1st May [430] Staff members called upon to perform their duties: -217 Total number of forms expected to be returned 1442 It was presumed that all those who had not returned their forms had not taken part in the work stoppage. After a count and verification of the questionnaires (returned up to 11 May) together with a representative of the Staff Association, the results are the following: Those who specifically indicated that they took part in the concerted work stoppage: 166 11.5% YES Non-participation 1276 88.5% NO of which, those who wanted to indicate that they did not ta...

The Concert system - Compiler and runtime technology for efficient concurrent object-oriented programming

Science.gov (United States)

Chien, Andrew A.; Karamcheti, Vijay; Plevyak, John; Sahrawat, Deepak

1993-01-01

Concurrent object-oriented languages, particularly fine-grained approaches, reduce the difficulty of large scale concurrent programming by providing modularity through encapsulation while exposing large degrees of concurrency. Despite these programmability advantages, such languages have historically suffered from poor efficiency. This paper describes the Concert project whose goal is to develop portable, efficient implementations of fine-grained concurrent object-oriented languages. Our approach incorporates aggressive program analysis and program transformation with careful information management at every stage from the compiler to the runtime system. The paper discusses the basic elements of the Concert approach along with a description of the potential payoffs. Initial performance results and specific plans for system development are also detailed.

An adaptive, data driven sound field control strategy for outdoor concerts

DEFF Research Database (Denmark)

Heuchel, Franz Maria; Caviedes Nozal, Diego; Brunskog, Jonas

2017-01-01

One challenge of outdoor concerts is to ensure adequate levels for the audience while avoiding disturbance of the surroundings. We outline the initial concept of a sound field control (SFC) system for tackling this issue using sound-zoning. The system uses Bayesian inference to update a sound...

Measured Early Lateral Energy Fractions in Concert Halls and Opera Houses

Science.gov (United States)

BARRON, M.

2000-04-01

In the 30 years since early lateral reflections were first suggested as important for concert halls, spatial impression and source broadening have become almost universally accepted as essential characteristics of halls with good acoustics. Two objective measures of source broadening have been proposed. Measured values of the best defined of these measures, the early lateral energy fraction (LF), are considered here. Results from two independent measurement surveys are discussed. Comparisons of LF values by hall show a significant link between hall mean LF and hall width. There is however considerable overlap between measured LF values in different halls so the relevance of describing halls by their mean early lateral energy fraction values is questionable. The behaviour of LF values within auditoria is discussed for different concert hall plan forms and within opera houses. A measure of source broadening including sound level is proposed and results considered in the context of auditorium design.

Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming

Directory of Open Access Journals (Sweden)

Jun Chen

2016-02-01

Full Text Available The core pluripotency factor Oct4 plays key roles in somatic cell reprogramming through transcriptional control. Here, we profile Oct4 occupancy, epigenetic changes, and gene expression in reprogramming. We find that Oct4 binds in a hierarchical manner to target sites with primed epigenetic modifications. Oct4 binding is temporally continuous and seldom switches between bound and unbound. Oct4 occupancy in most of promoters is maintained throughout the entire reprogramming process. In contrast, somatic cell-specific enhancers are silenced in the early and intermediate stages, whereas stem cell-specific enhancers are activated in the late stage in parallel with cell fate transition. Both epigenetic remodeling and Oct4 binding contribute to the hyperdynamic enhancer signature transitions. The hierarchical Oct4 bindings are associated with distinct functional themes at different stages. Collectively, our results provide a comprehensive molecular roadmap of Oct4 binding in concert with epigenetic rearrangements and rich resources for future reprogramming studies.

Not your grandfather's concert hall

Science.gov (United States)

Cooper, Russell; Malenka, Richard; Griffith, Charles; Friedlander, Steven

2004-05-01

The opening of Judy and Arthur Zankel Hall on 12 September 2003, restores Andrew Carnegie's original 1891 concept of having three outstanding auditoriums of different sizes under one roof, and creates a 21st-century venue for music performance and education. With concerts ranging from early music to avant-garde multimedia productions, from jazz to world music, and from solo recitals to chamber music, Zankel Hall expands the breadth and depth of Carnegie Hall's offerings. It allows for the integration of programming across three halls with minifestivals tailored both to the size and strengths of each hall and to the artists and music to be performed. The new flexible space also provides Carnegie Hall with an education center equipped with advanced communications technology. This paper discusses the unique program planned for this facility and how the architects, theatre consultants, and acousticians developed a design that fulfilled the client's expectations and coordinated the construction of the facility under the floor of the main Isaac Stern Auditorium without having to cancel a single performance.

Living Room vs. Concert Hall: Patterns of Music Consumption in Flanders

Science.gov (United States)

Roose, Henk; Stichele, Alexander Vander

2010-01-01

In this article we probe the interplay between public and private music consumption using a large-scale survey of the Flemish population in Belgium. We analyze whether public and private music consumption have different correlates and to what extent there is convergence between the genres that people listen to at home and at concerts. Results show…

Concert | The CERN Choir hits the high notes | Victoria Hall | 30 September

CERN Multimedia

2014-01-01

60 – 40 – 25: a series of numbers that have inspired an exceptional concert. They refer to the 60th anniversary of CERN, the 40th anniversary of the CERN Choir and the 25th anniversary of its direction by Gonzalo Martinez. On the occasion of this collision of anniversaries, the Committee of this CERN club decided to organise an appropriately significant event to celebrate the important worldwide role that CERN has played for 60 years, the fact that the CERN Choir has brought together amateur singers for 40 years, and finally the decisive role in the Choir’s history of its director, Gonzalo Martinez.   The work chosen for this concert also had to be something exceptional. A work which, through its monumental status, its brilliance, its innovation, its originality and its energy, symbolises CERN’s scientific discoveries, reflects the genius of its creator and represents the highest creative ambitions: Beethoven’s Missa Solemnis.  Perfor...

Concert | The CERN Choir hits the high notes | Victoria Hall | 30 September

CERN Document Server

2014-01-01

60 – 40 – 25: a series of numbers that have inspired an exceptional concert. They refer to the 60th anniversary of CERN, the 40th anniversary of the CERN Choir and the 25th anniversary of its direction by Gonzalo Martinez. On the occasion of this collision of anniversaries, the Committee of this CERN club decided to organise an appropriately significant event to celebrate the important worldwide role that CERN has played for 60 years, the fact that the CERN Choir has brought together amateur singers for 40 years, and finally the decisive role in the Choir’s history of its director, Gonzalo Martinez.   The work chosen for this concert also had to be something exceptional. A work which, through its monumental status, its brilliance, its innovation, its originality and its energy, symbolises CERN’s scientific discoveries, reflects the genius of its creator and represents the highest creative ambitions: Beethoven’s Missa Solemnis.  Perfo...

The American Board of Emergency Medicine ConCert Examination: Emergency Physicians' Perceptions of Learning and Career Benefits.

Science.gov (United States)

Marco, Catherine A; Wahl, Robert P; Counselman, Francis L; Heller, Barry N; Harvey, Anne L; Joldersma, Kevin B; Kowalenko, Terry; Coombs, Andrea B; Reisdorff, Earl J

2016-09-01

As part of the American Board of Emergency Medicine (ABEM) Maintenance of Certification (MOC) program, ABEM-certified physicians are required to pass the Continuous Certification (ConCert) examination at least every 10 years. With the 2015 ConCert examination, ABEM sought to better understand emergency physicians' perceptions of the benefits of preparing for and taking the examination and the career benefits of staying ABEM-certified. This was a prospective survey study. A voluntary postexamination survey was administered at the end of the 2015 ABEM ConCert examination (September 21-26, 2015). Physicians were asked about the benefits of preparing for the examination and maintaining ABEM certification. Examination performance was compared to perceptions of learning and career benefits. Of the 2,601 on-time test takers, 2,511 respondents participated (96.5% participation rate). The majority of participants (92.0%) identified a benefit to preparing for the ConCert examination, which included reinforced medical knowledge (73.9%), increased knowledge (66.8%), and making them a better clinician (39.4%). The majority of respondents (90.8%) identified a career benefit of maintaining ABEM certification, which included more employment options (73.8%), more positively viewed by other physicians (56.8%), and better financial outcomes (29.8%). There was a statistically significant association between the perception of knowledge reinforcement and examination performance (p Medicine.

Statistical relations among architectural features and objective acoustical measurements of concert halls

DEFF Research Database (Denmark)

Gade, Anders Christian; Siebein, G. W.; Chiang, W.

1993-01-01

as for entire rooms. Measurements data from all three teams were used in the models to assess the sensitivity of the models to expect variations in measurements. The results were compared to the previous work of Barron, Gade, and Hook among others. [Work supported by the National Science Foundation and Concert...

The virtual reconstruction of the ancient Roman concert hall in Aphrodisias, Turkey

DEFF Research Database (Denmark)

Rindel, Jens Holger; Gade, Anders Christian; Nielsen, Martin Lisa

2006-01-01

About two thousand years ago one of the world’s earliest and most beautiful concert halls were built in the city Aphrodisias, named after the goddess Aphrodite. It was a rich society, renowned for its marble and mastery in sculptures. Like many other cities in the Roman Empire there was an open...

Density functional theory study of the concerted pyrolysis mechanism for lignin models

Science.gov (United States)

Thomas Elder; Ariana Beste

2014-01-01

ABSTRACT: Studies on the pyrolysis mechanisms of lignin model compounds have largely focused on initial homolytic cleavage reactions. It has been noted, however, that concerted mechanisms may also account for observed product formation. In the current work, the latter processes are examined and compared to the former, by the application of density functional theory...

Design of concert hall in uremia based on notification to hidden role ...

African Journals Online (AJOL)

The growth of sound in a concert hall is reviewed with emphasis on hearing the direct sound clearly. Architecture in its daily means provides renewed space and is replaced within a larger space and people are moving in it and in it's around. Music is purely mechanical conception, organized and deliberate scattering of ...

“AGREEMENTS”, “DECISIONS” AND “CONCERTED PRACTICES”: KEY CONCEPTS IN THE ANALYSIS OF ANTICOMPETITIVE AGREEMENTS

Directory of Open Access Journals (Sweden)

CRISTINA CUCU

2013-05-01

Full Text Available In their economic activity, undertakings conclude many agreements between them. But agreements between undertakings which can distort the competition -anticompetitive agreements- are prohibited. The Romanian and EU law prohibit “all agreements between undertakings, decisions by associations of undertakings and concerted practices which have as their object or effect the prevention, restriction or distortion of competition”. However, the terms ”agreements”, ”decisions” or ”concerted practices” are nowhere defined in the EU Treaties or in the Romanian law. These terms are key concepts in the analysis of anticompetitive agreements which can distort the competition. In the lack of a legal definition, these concepts have generated a complex body of jurisprudence, which has to be identified. The analysis of these key concepts necessarily entails the conceptual delimitation of the notions. On this purpose, the relevant legal provisions will be identified in the Romanian and EU law, as well as the decisions of the European Court of Justice in this matter. The present paper intends to present the conceptual evolution of the analysed notions, paying special attention to concerted practices and to parallel behaviour in price fixing on the market.

A new concert hall for the city of Eindhoven : design and model tests

NARCIS (Netherlands)

Braat-Eggen, P.E.; van Luxemburg, Renz; Booy, L.G.; de Lange, P.A.

1993-01-01

A music centre containing a large (1300 seats) and a small (400 seats) concert hall has been built in the city of Eindhoven. The music centre is integrated into a larger building complex, called the ‘Heuvel-Galerie’, with shopping area (malls), recreational facilities, parking, offices and

A tablet app to enrich the live and post-live experience of classical concerts

NARCIS (Netherlands)

Melenhorst, M.S.; Van der Sterren, R.; Arzt, A.; Martorell, A.; Liem, C.C.S.

2015-01-01

This demonstration paper describes a tablet application that is developed to make classical concerts more accessible and more enjoyable for a broader audience. The app offers interactive visualizations of a symphony’s instrumentation and its score. It also offers timed background information about

Les concerts européens à la radio dans l'entre-deux-guerres : mise en ondes d'une métaphore diplomatique

NARCIS (Netherlands)

Laborie, L.; Lommers, S.B.

2008-01-01

L’expression « concert européen » s’applique à la fois aux relations diplomatiques tissées entre les Etats au xixe siècle et à la diffusion d’émissions musicales à l’échelle continentale entre 1929 et 1939. Au-delà des prouesses techniques, l’ambition culturelle et pacifiste de ces concerts

The Flux Database Concerted Action (invited paper)

International Nuclear Information System (INIS)

Mitchell, N.G.; Donnelly, C.E.

2000-01-01

The background to the IUR action on the development of a flux database for radionuclide transfer in soil-plant systems is summarised. The action is discussed in terms of the objectives, the deliverables and the progress achieved by the flux database working group. The paper describes the background to the current initiative, outlines specific features of the database and supporting documentation, and presents findings from the working group's activities. The aim of the IUR flux database working group is to bring together researchers to collate data from current experimental studies investigating aspects of radionuclide transfer in soil-plant systems. The database will incorporate parameters describing the time-dependent transfer of radionuclides between soil, plant and animal compartments. Work under the EC Concerted Action considers soil-plant interactions. This initiative has become known as the radionuclide flux database. It is emphasised that the word flux is used in this case simply to indicate the flow of radionuclides between compartments in time. (author)

Organiser la proximité entre usagers de l’eau : le cas de la Gestion Volumétrique dans le Bassin de la Charente

Directory of Open Access Journals (Sweden)

Céline Granjou

2006-05-01

Full Text Available Depuis les années 90 en Charente, la Gestion Volumétrique (GV vise à réduire les conflits liés au poids de l’irrigation sur la ressource en eau. Nous proposons ici de recourir au cadre d’analyse des proximités afin de formuler une évaluation sociologique du dispositif de gestion concertée de l’eau que constitue la GV. À partir d’entretiens auprès des acteurs de l’eau (irrigants, pêcheurs, riverains, acteurs du tourisme…, nous montrons que si la GV instaure une nouvelle proximité autour de règles d’organisation, celle-ci demeure asymétrique (privilégiant une proximité sectorielle autour de l’irrigation, instrumentale (absence d’un projet partagé de développement territorial, et enfin partielle au sens où n’est pas prise en compte la diversité des interdépendances de proximité autour de l’eau.Since the 90’s in the French region watered by the river Charente water resources have been weighed down with irrigation. In order to reduce conflicts which are linked to this situation, «Volumetric Management » introduces some new rules for irrigation practices including consultation. We propose to make a sociological assessment of the Volumetric Management basing on the notion of proximity with its different meanings. Several interviews with water users (farmers which use or don’t use water, fishers, residents, actors responsible for tourism… show that a new proximity due the share of organisation rules has been developed, but that this proximity is: asymmetric because it privileges links between partisans of irrigation; instrumental because it lacks a commune long-term vision of territorial development; at last partial because the different interdependencies induced by the same water resource are not considered.

Pilot study: Exposure and materiality of the secondary room and its impact in the impulse response of coupled-volume concert halls

Science.gov (United States)

Ermann, Michael; Johnson, Marty E.

2002-05-01

What does one room sound like when it is partially exposed to another (acoustically coupled)? More specifically, this research aims to quantify how operational and design decisions impact aural impressions in the design of concert halls with acoustical coupling. By adding a second room to a concert hall, and designing doors to control the sonic transparency between the two rooms, designers can create a new, coupled acoustic. Concert halls use coupling to achieve a variable, longer, and distinct reverberant quality for their musicians and listeners. For this study, a coupled-volume shoebox concert hall was conceived with a fixed geometric volume, form, and primary-room sound absorption. Aperture size and secondary-room sound-absorption levels were established as variables. Statistical analysis of sound decay in this simulated hall suggests a highly sensitive relationship between the double-sloped condition and (1) Architectural composition, as defined by the aperture size exposing the chamber and (2) Materiality, as defined by the sound absorbance in the coupled volume. Preliminary calculations indicate that the double-sloped sound decay condition only appears when the total aperture area is less than 1.5% of the total shoebox surface area and the average absorption coefficient of the coupled volume is less than 0.07.

Unequal Academic Achievement in High School: The Mediating Roles of Concerted Cultivation and Close Friends

Science.gov (United States)

Carolan, Brian V.

2016-01-01

Building from the classic Wisconsin model of status attainment, this study examines whether a specific style of parenting, concerted cultivation, and a close friend's school-related attitudes and behaviors mediate the relationship between a family's socioeconomic status and their child's academic achievement in the United States. Using a recursive…

Crisis behavior: An exploration of theories in concert.

Science.gov (United States)

McConnell, Jason B; Crudo, Christine

2015-01-01

How might prominent existing communication theory better explain behavior in a crisis context, when considered in concert with one another? This theoretical work highlights the insight to be gained using Situational Crisis Communication Theory and Bandura's notions of self-efficacy to heighten the explanatory power of the Theory of Planned Behavior as applied to communication during times of crisis. Situational Crisis Communication Theory better explains how past experience with crisis influences the attitudes and social norms of crisis behavior, while Bandura's notion of self-efficacy speaks more directly to the availability of resources as contributing factors to perceived behavioral control in a crisis situation. As such, the incorporation of these well-developed notions into the broader framework of the Theory of Planned Behavior affords greater understanding of the relationship between communication and behavior during a crisis. Further exploration of this theoretical relationship is warranted.

GENESIS OF KHARKOV MUSIC CULTURE IN THE HIGHLIGHT OF THE CITY’S EDUCATION AND CONCERT LIFE FORMATION

Directory of Open Access Journals (Sweden)

Olena Kononova

2016-02-01

Full Text Available The article highlights the genesis of Kharkov musical culture from the late 18th to the first half of the 19th century, studying it in terms of two aspects, the formation of education and the emergence of the city’s concert life.The relevance of the research subject chosen by the author is determined by the wish to give the fullest description of the multi-layered process of formation of Kharkov musical culture which played one of the leading roles in the history of Ukrainian culture, and to acquaint the Western public with the most interesting facts of the formation and development of a reputable East-European centre. The main range of issues discussed in the article covers the period of the innitial foundation of artistic education, and its influence on the expansion and perception of music in different social circles, presenting the structures and forms of the nascent musical life of Kharkov. The section "Specific features of the Ukrainian system of education" brings out the facts which indicate the progressive tendencies in education, especially, on the territory of Sloboda Ukraine. The formation of artistic education in the religious schools of the city is covered in the section "Genesis of musical education in Kharkov". One of the most productive periods of the city’s cultivation of concert life associated with the functioning of the University is analyzed in the section "The impact of the University music activities on the city's concert going." The Conclusion emphasizes the interaction of traditional and nontraditional in the musical culture of Kharkov that was clearly manifested in the concert activities of the University, in particular, in popularization of oratorios. Furthermore, it discusses the factors which participated in the development in the field of compositional achievement as well as the performing arts and opened new perspectives in the dynamics of the artistic life of the Ukrainian city.

Accelerating cleanup. Paths to closure Hanford Site

International Nuclear Information System (INIS)

Edwards, C.

1998-01-01

This document was previously referred to as the Draft 2006 Plan. As part of the DOE's national strategy, the Richland Operations Office's Paths to Closure summarizes an integrated path forward for environmental cleanup at the Hanford Site. The Hanford Site underwent a concerted effort between 1994 and 1996 to accelerate the cleanup of the Site. These efforts are reflected in the current Site Baseline. This document describes the current Site Baseline and suggests strategies for further improvements in scope, schedule and cost. The Environmental Management program decided to change the name of the draft strategy and the document describing it in response to a series of stakeholder concerns, including the practicality of achieving widespread cleanup by 2006. Also, EM was concerned that calling the document a plan could be misconstrued to be a proposal by DOE or a decision-making document. The change in name, however, does not diminish the 2006 vision. To that end, Paths to Closure retains a focus on 2006, which serves as a point in time around which objectives and goals are established

Stepwise or concerted? DFT study on the mechanism of ionic Diels-Alder reaction of chromanes

Directory of Open Access Journals (Sweden)

Haghdadi Mina

2016-01-01

Full Text Available The stepwise and concerted Ionic Diels-Alder reaction between phenyl (pyridin-2-ylmethylene oxonium and styrene derivatives are explored using theoretical method. The results support using computational method via persistent intermediates. The DFT method was essential to reproduce a reasonable potential energy surface for these challenging systems.

Concerted evolution of sea anemone neurotoxin genes is revealed through analysis of the Nematostella vectensis genome.

Science.gov (United States)

Moran, Yehu; Weinberger, Hagar; Sullivan, James C; Reitzel, Adam M; Finnerty, John R; Gurevitz, Michael

2008-04-01

Gene families, which encode toxins, are found in many poisonous animals, yet there is limited understanding of their evolution at the nucleotide level. The release of the genome draft sequence for the sea anemone Nematostella vectensis enabled a comprehensive study of a gene family whose neurotoxin products affect voltage-gated sodium channels. All gene family members are clustered in a highly repetitive approximately 30-kb genomic region and encode a single toxin, Nv1. These genes exhibit extreme conservation at the nucleotide level which cannot be explained by purifying selection. This conservation greatly differs from the toxin gene families of other animals (e.g., snakes, scorpions, and cone snails), whose evolution was driven by diversifying selection, thereby generating a high degree of genetic diversity. The low nucleotide diversity at the Nv1 genes is reminiscent of that reported for DNA encoding ribosomal RNA (rDNA) and 2 hsp70 genes from Drosophila, which have evolved via concerted evolution. This evolutionary pattern was experimentally demonstrated in yeast rDNA and was shown to involve unequal crossing-over. Through sequence analysis of toxin genes from multiple N. vectensis populations and 2 other anemone species, Anemonia viridis and Actinia equina, we observed that the toxin genes for each sea anemone species are more similar to one another than to those of other species, suggesting they evolved by manner of concerted evolution. Furthermore, in 2 of the species (A. viridis and A. equina) we found genes that evolved under diversifying selection, suggesting that concerted evolution and accelerated evolution may occur simultaneously.

Chinese Islam: A Complete Concert

Directory of Open Access Journals (Sweden)

Zvi Ben-Dor Benite

2017-06-01

Full Text Available Matthew S. Erie, China and Islam: The Prophet, the Party, and Law. Cambridge University Press, 2016. 472 pp. $140 (cloth/e-book. Jonathan Lipman, ed., Islamic Thought in China: Sino-Muslim Intellectual Evolution from the 17th to the 20th Century. Edinburgh University Press, 2016. 288 pp. £70 (cloth; e-book. Roberta Tontini, Muslim Sanzijing: Shifts and Continuities in the Definition of Islam in China. Brill, 2016. 238 pp. $125 (cloth. Why study a Chinese “minority” and its history? The task of scholars of Chinese Islam since the 1990s has been twofold: on the one hand, we have wanted to study Islam in China in its Chinese social and cultural context, as opposed to imagining it as a single separate entity, and to show that its history is relevant and meaningful for Chinese history in general. One could almost say that this goal was achieved a while ago. The next task has been to make the study of Chinese Islam and its history meaningful and useful for the greater community of scholars of Islam in general. It seems to me that with the books reviewed here, and with others in the making, we are getting close to reaching this target. In 1910, Marshall Broomhall’s Islam in China declared that Chinese Islam was a “neglected problem.” These books show that it is no longer neglected, and no longer a “problem”; rather, it is an exciting topic. Indeed, a complete, even if not harmonious, concert.

Creating personalized memories from social events: community-based support for multi-camera recordings of school concerts

NARCIS (Netherlands)

R.L. Guimarães (Rodrigo); P.S. Cesar Garcia (Pablo Santiago); D.C.A. Bulterman (Dick); V. Zsombori; I. Kegel

2011-01-01

htmlabstractThe wide availability of relatively high-quality cameras makes it easy for many users to capture video fragments of social events such as concerts, sports events or community gatherings. The wide availability of simple sharing tools makes it nearly as easy to upload individual fragments

Bringing Astronomy Directly to New Audiences (50,000 People) at Outdoor Concerts and Music Festivals

Science.gov (United States)

Lubowich, D.

2014-07-01

My NASA-funded Music and Astronomy Under the Stars (MAUS) has brought astronomy to 50,000 music lovers at the National Mall (co-sponsor OSTP); Central Park Jazz, Newport Folk, Ravinia, or Tanglewood music festivals; and classical, folk, pop/rock, opera, Caribbean, or county-western concerts in parks assisted by astronomy clubs (55 events since 2009). Yo-Yo-Ma, the Chicago and Boston Symphony Orchestras, Ravi Coltrane, Esperanza Spalding, Phish, Blood Sweat and Tears, Deep Purple, Tony Orlando, and Wilco performed at these events. MAUS combines solar, optical, and radio telescope observations; large posters/banners (From the Earth to the Universe; Visions of the Universe); videos; hands-on activities (Night Sky Network; Harvard-Smithsonian CfA); imaging with a cell phone mount; and hand-outs (info on science museums, astronomy clubs, and citizen science) before and after the concerts or at intermission. MAUS reached underserved groups and attracted large enthusiastic crowds. Many young children participated in this family learning experience-often the first time they looked through a telescope. Outcomes: While education!

Conference-concert with Frédéric Bernachon on Thursday, 8 March at 6 pm

CERN Multimedia

Staff Association

2018-01-01

The Staff Association is pleased to invite you to an educational conference-concert of classical piano by Frédéric Bernachon « Beethoven : sa vie et son destin au cœur de la sonate Pathétique » on Thursday, 8 March at 6 pm Main Auditorium (500-1-001) Length: 60-90 minutes. Free entrance, cocktails served after the concert. External visitors, please contact the Staff Association for a visitor card: staff.association@cern.ch or +41 22 76 63738 With the help of a piano, Frédéric Bernachon proposes to explain the tragedy of Beethoven, as transmitted in his musical legacy. The listeners will get to experience Ludwig van Beethoven's destiny, suspense, drama and great questions in all their range and variety. After a careful introduction to listening to Sonate Pathétique, Frédéric Bernachon himself interprets this unique piece, through which Beethowen has chosen...

Aperture size, materiality of the secondary room and listener location: Impact on the simulated impulse response of a coupled-volume concert hall

Science.gov (United States)

Ermann, Michael; Johnson, Marty E.; Harrison, Byron W.

2003-04-01

By adding a second room to a concert hall, and designing doors to control the sonic transparency between the two rooms, designers can create a new, coupled acoustic. Concert halls use coupling to achieve a variable, longer and distinct reverberant quality for their musicians and listeners. For this study, a coupled-volume concert hall based on an existing performing arts center is conceived and computer-modeled. It has a fixed geometric volume, form and primary-room sound absorption. Ray-tracing software simulates impulse responses, varying both aperture size and secondary-room sound absorption level, across a grid of receiver (listener) locations. The results are compared with statistical analysis that suggests a highly sensitive relationship between the double-sloped condition and the architecture of the space. This line of study aims to quantitatively and spatially correlate the double-sloped condition with (1) aperture size exposing the chamber, (2) sound absorptance in the coupled volume, and (3) listener location.

Standing Concertation Commmittee - Ordinary meeting on 10 May 2007

CERN Multimedia

2007-01-01

At its meeting on 10 May 2007, the Standing Concertation Committee discussed the Management’s proposal for the revision of Annex A 1 of the Staff Rules and Regulations. Annex A 1 sets out the principles for future periodic reviews of the personnel’s financial and social conditions and the revision reflects the modifications to review methods decided by the CERN Council in December 2006. The aim is to simplify the processes involved and rationalize the use of resources. The data collection process will be outsourced to a greater extent. The new methods also aim to reduce the overall time required to complete future reviews. Details of procedure will be addressed in subsequent discussions. The Committee approved the document for submission to the Tripartite Employment Conditions Forum (TREF) at its meeting on 31 May and 1 June 2007.

Standing Concertation Commmittee - Ordinary meeting on 10 May 2007

CERN Multimedia

HR Department

2007-01-01

At its meeting on 10 May 2007, the Standing Concertation Committee discussed the Management's proposal for the revision of Annex A 1 of the Staff Rules and Regulations. Annex A 1 sets out the principles for future periodic reviews of the personnel's financial and social conditions and the revision reflects the modifications to review methods decided by the CERN Council in December 2006. The aim is to simplify the processes involved and rationalize the use of resources. The data collection process will be outsourced to a greater extent. The new methods also aim to reduce the overall time required to complete future reviews. Details of procedure will be addressed in subsequent discussions. The Committee approved the document for submission to the Tripartite Employment Conditions Forum (TREF) at its meeting on 31 May and 1 June 2007.

Framework for DOE mixed low-level waste disposal: Site fact sheets

Energy Technology Data Exchange (ETDEWEB)

Gruebel, M.M.; Waters, R.D.; Hospelhorn, M.B.; Chu, M.S.Y. [eds.

1994-11-01

The Department of Energy (DOE) is required to prepare and submit Site Treatment Plans (STPS) pursuant to the Federal Facility Compliance Act (FFCAct). Although the FFCAct does not require that disposal be addressed in the STPS, the DOE and the States recognize that treatment of mixed low-level waste will result in residues that will require disposal in either low-level waste or mixed low-level waste disposal facilities. As a result, the DOE is working with the States to define and develop a process for evaluating disposal-site suitability in concert with the FFCAct and development of the STPS. Forty-nine potential disposal sites were screened; preliminary screening criteria reduced the number of sites for consideration to twenty-six. The DOE then prepared fact sheets for the remaining sites. These fact sheets provided additional site-specific information for understanding the strengths and weaknesses of the twenty-six sites as potential disposal sites. The information also provided the basis for discussion among affected States and the DOE in recommending sites for more detailed evaluation.

Following Musical Shows: A Study with Focal Groups on Satisfaction of Musical Concerts Regular Visitors and Socialization between Them

Directory of Open Access Journals (Sweden)

Lúmia Massa Garcia Pires

2017-06-01

Full Text Available This article aimed to identify which attributes impact more significantly on the satisfaction of concerts’ regular visitors and socialization between them when inserted in these kinds of events. Thus, we used a qualitative methodology, performing focus groups. Among the main results of this study, we found, regarding satisfaction of concerts’ visitors, the attributes that most influence the public are related to services - especially for beverage supply, cleaning of bathrooms and lines formed inside the event - organization, show infrastructure and performance artists. Furthermore, considering the socialization of the visitors, we found that most respondents often go to concerts together with other people, but some did not exclude the possibility to attend the concerts alone when it comes to a familiar artist.

Automatic device for compensating the earths, magnetic field around a {beta} spectrometer; Ensemble automatique de compensation du champ terrestre autour d'un spectrometre

Energy Technology Data Exchange (ETDEWEB)

Ristori, Ch [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

1967-02-15

This paper shows how the earth magnetic field inside a double focusing, {pi}{radical}2, iron free, beta ray spectrometer (radius 50 cm ) has been compensated. Three orthogonal magnetic fields are generated by three square coils sets. Each stabilized power supply is regulated through its own magnetometer (of the fluxgate type) and the earth field inside the spectrometer is compensated to 10{sup -4} Oe whatever the earth field or power supply oscillation could be. (author) [French] Cette etude a pour but de compenser le champ magnetique terrestre autour d'un spectrometre beta {pi}{radical}2 a double focalisation, a bobines sans fer et de rayon moyen des trajectoires de 50 cm. Le champ magnetique terrestre est compense par superposition de trois champs orthogonaux, chacun cree par un ensemble de cadres carres. Chacune de ces composantes est mesuree par un magnetometre. Cet ensemble permet de travailler en regulation de courant ou en regulation de champ. En regulation de courant, l'operation est manuelle. En regulation de champ, pour chaque groupe de cadres, l'alimentation stabilisee est asservie par son magnetometre et malgre les variations du champ terrestre ou de la tension secteur, la compensation du champ terrestre se fait toujours correctement au niveau du spectrometre, a 10{sup -4} Oe pres. (auteur)

Créer un site pour mieux apprendre ? Bilan d'expérience

Directory of Open Access Journals (Sweden)

Martine Eisenbeis

2005-11-01

Full Text Available Cet article fait le point sur la mise en place d'un atelier de création d'un site Internet dans le cadre de l'enseignement universitaire du Français Langue Étrangère, réflexion fondée entre autres sur un corpus d'entretiens avec des étudiants ayant participé à ce projet. Ce bilan s'articule autour de trois axes de réflexion : les spécificités du support Internet, source de motivation et base d'un apprentissage collaboratif et de l'acquisition d'un lexique et d'un savoir-faire spécifiques ; la place de la médiation humaine, la redistribution des rôles et la diversité des interactions dans les différentes tâches mises en œuvre ; la dimension actionnelle et autonomisante d'un tel projet. La conclusion propose des pistes pour reconduire ou prolonger cet atelier en vue d'une meilleure intégration pédagogique et institutionnelle

Standing Concertation Committee - Ordinary Meeting on 3 September 2008

CERN Multimedia

HR Department

2008-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 3 September 2008 included: Education fees: Indexation of the amounts for accommodation and meals The Committee approved the indexation calculations for accommodation and meals for the academic year 2008-2009. With the indexation of the lump sum payments, accommodation costs for the academic year 2007-2008 will be reimbursed at 529 CHF per month (previously CHF 500). Meals will be reimbursed at 17.50 CHF per meal (unchanged). The ceiling for school transport has been increased from 600 CHF to 622 CHF. Administrative Circular No. 26 (Rev. 8) The Committee took note of the modifications to Administrative Circular No. 26 (Rev. 8) ‘Recognition of merit of staff members’, concerning provision for the award of exceptional advancement outside the annual advancement exercise to recognize, for example, the completion of a major project. HR Survey The Committee took note of the Head of HR Department...

STANDING CONCERTATION COMMMITTEE - ORDINARY MEETING ON 26 JUNE 2007

CERN Multimedia

HR Department

2007-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 26 June 2007 included: Mutual Aid Fund The Committee took note of the annual report for 2006 by the Chairman of the Mutual Aid Fund and approved contributions to the Fund’s budget from the Management and the Staff Association and thanked the members of the Fund for their work. Administrative Circular No. 12 A (Rev. 1) - Education Fees The Committee agreed to recommend Administrative Circular No. 12 A entitled "Education Fees" to the Director-General for approval. The circular is applicable to staff, fellows and scientific associates recruited from 1st January 2007 and to staff who were recruited as Local Staff before that date. Further details of reimbursement of school fees will shortly be available in the form of Frequently Asked Questions on the HR Department website. Administrative Circular No. 31 (Rev. 1) - International Indemnity and Non-Resident Allowance The Committee agreed to reco...

STANDING CONCERTATION COMMMITTEE - ORDINARY MEETING ON 3 APRIL 2008

CERN Multimedia

HR Department

2008-01-01

The main items discussed at the meetings of the Standing Concertation Committee on 3 April 2008 included: External mobility The Committee took note of a progress report on external mobility after a run-in period of about six months. Based on the experience gained, it was agreed to broaden the scope of the programme and in particular to extend eligibility conditions to include: All staff members whose limited duration contract will end in less than one year, as well as all those with indefinite contracts; Fellows who have been employed by CERN for more than 18 months; Doctoral students who have been in the CERN doctoral programme for more than 2.5 years; Apprentices in the final year of their apprenticeship; Ex-members of the personnel who are receiving CERN unemployment benefits. An article in the Weekly Bulletin will follow and the relevant web pages will be updated. LHC achievement awards The Committee took note of the outcome of discussions between the Management and t...

STANDING CONCERTATION COMMMITTEE - ORDINARY MEETING ON 28 AUGUST 2007

CERN Multimedia

HR Department

2007-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 28 August 2007 included: Administrative Circular No. 12 A (Rev. 1) - Education Fees The Committee agreed to recommend Administrative Circular No. 12 A, "Education Fees", to the Director-General for approval. The circular is applicable to staff, fellows and scientific associates recruited before 1 January 2007 (except for local staff). Administrative Circular No. 12 B applies to those recruited from 1 January 2007 and was examined by the Committee in June 2007. It was noted that, at the initiative of HR Department, a number of important simplifications have been introduced. These cover, in particular, lump-sum payments to compensate for accommodation, meals and journey expenses. Further details of payment of education fees will shortly be available in the form of Frequently Asked Questions on the HR Department website. The Chairman thanked HR Department as well as "Team 7" members for init...

STANDING CONCERTATION COMMMITTEE - ORDINARY MEETING ON 28 AUGUST 2007

CERN Document Server

HR Department

2007-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 28 August 2007 included: Administrative Circular No. 12 A (Rev. 1) - Education Fees The committee agreed to recommend Administrative Circular No. 12 A, Education Fees, to the Director-General for approval. The circular is applicable to staff, fellows and scientific associates recruited before 1 January 2007 (except for local staff). Administrative Circular No. 12 B applies to those recruited from 1 January 2007 and was considered by the committee in June 2007. It was noted that, at the initiative of HR Department, a number of important simplifications have been introduced. These cover in particular lump sum payments to compensate for accommodation, meals and journey expenses. Further details of payment of education fees will shortly be available in the form of Frequently Asked Questions on the HR Department website. The Chairman thanked HR Department as well as "Team 7" members for initiating these simp...

Standing Concertation Commmittee - Ordinary meeting on 27 March 2007

CERN Multimedia

HR Department

2007-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 27 March 2007 included: Merit Recognition Guidelines In the context of the new Merit Appraisal and Recognition Scheme (MARS), the committee took note of the documents entitled 'MARS Guidelines 2007' and the 'Guidelines for Senior Staff Advancement 2007'. Follow-up of Finance Committee and Council meetings The Committee took note of the information provided by S. Lettow, the Director for Finance and Human Resources, including the possibility for a phased increase in Member State contributions from 2008. Registered partnerships It was agreed that staff members with registered partners should be reminded of the social cover available to their partners. Cover is limited to the CERN Health Insurance Scheme and partners may be covered by the Scheme only while the staff member is working. On the staff member's retirement or other change in status, or death, partners are no longer eligible for CHIS cover. Retirement semi...

Standing Concertation Commmittee - Ordinary meeting on 27 March 2007

CERN Multimedia

HR Department

2007-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 27 March 2007 included: Merit Recognition Guidelines : in the context of the new Merit Appraisal and Recognition Scheme (MARS), the committee took note of the documents entitled MARS Guidelines 2007 and the Guidelines for Senior Staff Advancement 2007. Follow-up of Finance Committee and Council meetings The Committee took note of the information provided by S. Lettow, the Director for Finance and Human Resources, including the possibility for a phased increase in Member State contributions from 2008. Registered partnerships It was agreed that staff members with registered partners should be reminded of the social cover available to their partners. Cover is limited to the CERN Health Insurance Scheme and partners may be covered by the Scheme only while the staff member is working. On the staff members retirement or other change in status, or death, partners are no longer eligible for CHIS cover. Retirement seminars It...

Standing Concertation Committee - Ordinary meeting on 25 June 2008

CERN Multimedia

HR Department

2008-01-01

The main items discussed at the meetings of the Standing Concertation Committee on 25 June 2008 included: Mutual Aid Fund The committee took note of the annual report for 2007 by the chairman of the Mutual Aid Fund and approved contributions to the Fund’s 2008 budget from the Management and the Staff Association. Results of 2008 MARS exercise and LHC achievement awards The committee took note of the Head of HR Department’s presentation of the results of the 2008 MARS exercise and the distribution of LHC achievement awards. It was noted that these awards would be granted with effect from 1 October 2008 (see Bulletin 18&19). The results show agreement with the 2008 MARS guidelines (see Bulletin 10&11) for the advancement ceilings per career path, the number of awards for extraordinary service, as well as the distribution of steps for the recognition of merit as shown in the SCC of 27 February (see Bulletin 14&15). Follow-up of Finance Committee and Council...

Standing Concertation Committee - Ordinary Meeting on 30 September 2008

CERN Multimedia

HR Department

2008-01-01

The main items discussed at the meetings of the Standing Concertation Committee on 30 September 2008 included: Part-time work as a pre-retirement measure The Committee agreed to recommend the Director-General to extend the scheme of part-time work as a pre-retirement measure by one year, i.e. until 31 December 2009. Preparation of TREF on 7 October 2008 The Committee took note that the TREF agenda would cover: Annual salary adjustment; Voluntary programmes; Five-yearly review of financial & social conditions of members of the personnel; Update on 2005 review; Preparation for 2010 review; TREF workplan 2009; Update on CHIS actuarial study. The proposals and presentations which the Management planned to present to TREF were discussed and some clarifications were agreed. Follow-up of Finance Committee and Council The Committee took note of a report by the Chairman of points related to personnel matters discussed in those committees. He mentioned in particular the annu...

Optimal Volume for Concert Halls Based on Ando’s Subjective Preference and Barron Revised Theories

Directory of Open Access Journals (Sweden)

Salvador Cerdá

2014-03-01

Full Text Available The Ando-Beranek’s model, a linear version of Ando’s subjective preference theory, obtained by the authors in a recent work, was combined with Barron revised theory. An optimal volume region for each reverberation time was obtained for classical music in symphony orchestra concert halls. The obtained relation was tested with good agreement with the top rated halls reported by Beranek and other halls with reported anomalies.

An efficient algorithm to perform local concerted movements of a chain molecule.

Directory of Open Access Journals (Sweden)

Stefano Zamuner

Full Text Available The devising of efficient concerted rotation moves that modify only selected local portions of chain molecules is a long studied problem. Possible applications range from speeding the uncorrelated sampling of polymeric dense systems to loop reconstruction and structure refinement in protein modeling. Here, we propose and validate, on a few pedagogical examples, a novel numerical strategy that generalizes the notion of concerted rotation. The usage of the Denavit-Hartenberg parameters for chain description allows all possible choices for the subset of degrees of freedom to be modified in the move. They can be arbitrarily distributed along the chain and can be distanced between consecutive monomers as well. The efficiency of the methodology capitalizes on the inherent geometrical structure of the manifold defined by all chain configurations compatible with the fixed degrees of freedom. The chain portion to be moved is first opened along a direction chosen in the tangent space to the manifold, and then closed in the orthogonal space. As a consequence, in Monte Carlo simulations detailed balance is easily enforced without the need of using Jacobian reweighting. Moreover, the relative fluctuations of the degrees of freedom involved in the move can be easily tuned. We show different applications: the manifold of possible configurations is explored in a very efficient way for a protein fragment and for a cyclic molecule; the "local backbone volume", related to the volume spanned by the manifold, reproduces the mobility profile of all-α helical proteins; the refinement of small protein fragments with different secondary structures is addressed. The presented results suggest our methodology as a valuable exploration and sampling tool in the context of bio-molecular simulations.

Synergistic Synthetic Biology: Units in Concert

Science.gov (United States)

Trosset, Jean-Yves; Carbonell, Pablo

2013-01-01

Synthetic biology aims at translating the methods and strategies from engineering into biology in order to streamline the design and construction of biological devices through standardized parts. Modular synthetic biology devices are designed by means of an adequate elimination of cross-talk that makes circuits orthogonal and specific. To that end, synthetic constructs need to be adequately optimized through in silico modeling by choosing the right complement of genetic parts and by experimental tuning through directed evolution and craftsmanship. In this review, we consider an additional and complementary tool available to the synthetic biologist for innovative design and successful construction of desired circuit functionalities: biological synergies. Synergy is a prevalent emergent property in biological systems that arises from the concerted action of multiple factors producing an amplification or cancelation effect compared with individual actions alone. Synergies appear in domains as diverse as those involved in chemical and protein activity, polypharmacology, and metabolic pathway complementarity. In conventional synthetic biology designs, synergistic cross-talk between parts and modules is generally attenuated in order to verify their orthogonality. Synergistic interactions, however, can induce emergent behavior that might prove useful for synthetic biology applications, like in functional circuit design, multi-drug treatment, or in sensing and delivery devices. Synergistic design principles are therefore complementary to those coming from orthogonal design and may provide added value to synthetic biology applications. The appropriate modeling, characterization, and design of synergies between biological parts and units will allow the discovery of yet unforeseeable, novel synthetic biology applications. PMID:25022769

Synergistic Synthetic Biology: Units in Concert

International Nuclear Information System (INIS)

Trosset, Jean-Yves; Carbonell, Pablo

2013-01-01

Synthetic biology aims at translating the methods and strategies from engineering into biology in order to streamline the design and construction of biological devices through standardized parts. Modular synthetic biology devices are designed by means of an adequate elimination of cross-talk that makes circuits orthogonal and specific. To that end, synthetic constructs need to be adequately optimized through in silico modeling by choosing the right complement of genetic parts and by experimental tuning through directed evolution and craftsmanship. In this review, we consider an additional and complementary tool available to the synthetic biologist for innovative design and successful construction of desired circuit functionalities: biological synergies. Synergy is a prevalent emergent property in biological systems that arises from the concerted action of multiple factors producing an amplification or cancelation effect compared with individual actions alone. Synergies appear in domains as diverse as those involved in chemical and protein activity, polypharmacology, and metabolic pathway complementarity. In conventional synthetic biology designs, synergistic cross-talk between parts and modules is generally attenuated in order to verify their orthogonality. Synergistic interactions, however, can induce emergent behavior that might prove useful for synthetic biology applications, like in functional circuit design, multi-drug treatment, or in sensing and delivery devices. Synergistic design principles are therefore complementary to those coming from orthogonal design and may provide added value to synthetic biology applications. The appropriate modeling, characterization, and design of synergies between biological parts and units will allow the discovery of yet unforeseeable, novel synthetic biology applications.

Warm-Up Activities of Middle and High School Band Directors Participating in State-Level Concert Band Assessments

Science.gov (United States)

Ward, Justin P.; Hancock, Carl B.

2016-01-01

The purpose of this study was to examine the warm-ups chosen by concert band directors participating in state-level performance assessments. We observed 29 middle and high school bands and coded the frequency and duration of warm-up activities and behaviors. Results indicated that most bands rehearsed music and played scales, long tones, and…

Bioaccessibilité et spéciation de l'arsenic des sols autour de l'ancien site minier de Salsigne

OpenAIRE

Tack , Karine; Mouton , Julia; Meunier , Laurent; Mestre-Pujol , Dominique; Denys , Sébastien

2009-01-01

National audience; La mine de Salsigne - La Combe du Saut, dans le département de l'Aude, exploitée depuis l'antiquité pour des métaux comme le fer, le cuivre, l'argent ou le plomb était connue en particulier pour l'or. Son extraction s'est avérée particulièrement polluante pour l'environnement d'une part par les fumées générées par le process mais également par les envols de poussières chargées en arsenic émises depuis les installations industrielles aux environs du site. Par ailleurs, lors ...

Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains.

Science.gov (United States)

Nakamura, Yuki; Hibino, Kayo; Yanagida, Toshio; Sako, Yasushi

2016-01-01

Son of sevenless (SOS) is a guanine nucleotide exchange factor that regulates cell behavior by activating the small GTPase RAS. Recent in vitro studies have suggested that an interaction between SOS and the GTP-bound active form of RAS generates a positive feedback loop that propagates RAS activation. However, it remains unclear how the multiple domains of SOS contribute to the regulation of the feedback loop in living cells. Here, we observed single molecules of SOS in living cells to analyze the kinetics and dynamics of SOS behavior. The results indicate that the histone fold and Grb2-binding domains of SOS concertedly produce an intermediate state of SOS on the cell surface. The fraction of the intermediated state was reduced in positive feedback mutants, suggesting that the feedback loop functions during the intermediate state. Translocation of RAF, recognizing the active form of RAS, to the cell surface was almost abolished in the positive feedback mutants. Thus, the concerted functions of multiple membrane-associating domains of SOS governed the positive feedback loop, which is crucial for cell fate decision regulated by RAS.

Chinese Dream——Concert in Commemoration of 115th Birth Anniversary of Premier Zhou Enlai Held

Institute of Scientific and Technical Information of China (English)

Our; Staff; Reporter

2013-01-01

<正>The theme song of the film The Founding of a Republic sung by male vocalists Dai Yuqiang and Wei Song reverberated in the Opera Hall at the National Center for the Performing Arts on the `evening of March 14. It marked the start of the concert in commemoration of the 115th anniversary of the birth of Premier Zhou Enlai, with "Chinese Dream" as the theme.

Dialogue autour de la notion de spectateur.

Directory of Open Access Journals (Sweden)

Arnaud Stinès

2005-03-01

Full Text Available L’œuvre de Slimane Raïs repose sur le lien social qu’il suscite. Au-delà d’un processus interactif où le spectateur serait amener à intervenir dans un dispositif plastique construit par l’artiste, la démarche de Raïs consiste surtout en la mise en relation de personnes à partir d’une proposition situationnelle. Comme le définit très justement Alain Livache (sur le site Articité , « l'œuvre n'est pas une conséquence de la relation engagée. L'œuvre est ...

CONCERT A high power proton accelerator driven multi-application facility concept

CERN Document Server

Laclare, J L

2000-01-01

A new generation of High Power Proton Accelerator (HPPA) is being made available. It opens new avenues to a long series of scientific applications in fundamental and applied research, which can make use of the boosted flux of secondary particles. Presently, in Europe, several disciplines are preparing their project of dedicated facility, based on the upgraded performances of HPPAs. Given the potential synergies between these different projects, for reasons of cost effectiveness, it was considered appropriate to look into the possibility to group a certain number of these applications around a single HPPA: CONCERT project left bracket 1 right bracket . The ensuing 2-year feasibility study organized in collaboration between the European Spallation Source and the CEA just started. EURISOL left bracket 2 right bracket project and CERN participate in the steering committee.

STANDING CONCERTATION COMMITTEE: ORDINARY MEETING ON 15 JANUARY 2004

CERN Document Server

2004-01-01

Original: English This meeting was devoted to the main topics summarised below. 1-Introduction by the Director-General Conveying his best wishes for the New Year to SCC members, the Director-General underlined the importance which he attaches to good relations with the staff and their representatives in the Staff Association. He would ensure open dialogue and make every effort to attend the SCC, at the request of the Staff Association or the Management representatives. The concertation process at the SCC and TREF is a most useful and necessary one for the Management in drawing up strategies that are clearly announced and understood by all parties. He trusted that the SCC would play a vital role in realising related programmes and in optimising their implementation. He also wished to pass a message to the staff at large on the importance of good, efficient management, understood in its widest sense and at all levels. The role of supervisors is not only to lead their teams in the scientific and technical doma...

STANDING CONCERTATION COMMITTEE ORDINARY MEETING ON 24 JANUARY 2001

CERN Multimedia

2001-01-01

This meeting was mainly devoted to follow-up from the meetings of the Finance Committee and Council in December 2000, as well as to the work planning of the SCC for 2001. The newly-appointed Chairman of SCC, J. van der Boon, welcomed the Director-General and members to this first meeting of the new year, underlining his objective of maintaining a positive climate of concertation in the best interests of the Organization and its personnel. The President of the Staff Association declared that the latter would actively pursue its role in the same spirit. 1. Follow-up from the meetings of the Finance Committee and Council in December 2000 The Director-General, underlining the positive outcome of the 5-yearly review, conveyed his thanks to all parties that had taken part and, in particular, to the Staff Association for its constructive contribution to reach the compromise accepted by the three parties. After discussion of decisions on the package of measures approved by Council last December and on related impleme...

Standing Concertation Committee - Ordinary Meeting on 4 December 2007

CERN Multimedia

HR Department

2008-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 4 December 2007 included: 2006 Medical Service Annual Report The Committee took note of the report by the head of the Medical Service, Dr V. Fassnacht, (see http://sc-me.web.cern.ch/sc-me/index.html) and of a number of points raised during the discussion, including the importance of further prevention measures. The Committee expressed its thanks to all members of the Medical Service for their work in 2006 and over the past year. Short-Term Saved leave Scheme As announced in Weekly Bulletins Nos. 28/2007 and 51/2007, the Saved Leave Scheme will be succeeded from 1 January 2008 by the Short-Term Saved Leave Scheme (see also https://hr-services.web.cern.ch/hr-services/services-Ben/sls_shortterm.asp). The Committee agreed to recommend the Director-General to adopt the relevant procedure. It was noted that staff could apply immediately to participate from 1 January 2008 and that applications to pa...

STANDING CONCERTATION COMMITTEE ORDINARY MEETING ON 4 SEPTEMBER 2003

CERN Multimedia

2003-01-01

This meeting was devoted to the main topics summarised below. 1. Information on the Organization's Human Resources Plan The SCC took note of the Chairman's presentation summarising the content of the HR Plan and the internal process that had been followed in drawing it up for approval by Council at the end of last year. The Staff Association expressed criticism concerning the lack of concertation in this process and, in particular, the Management's declared objective of achieving an overall 2:1 ratio of indefinite contracts to limited contracts of the staff by 2010, which it considers is not based on objective grounds. More importantly, the Staff Association criticised the fact that this ratio can only be arrived at under the assumption that no new project is initiated before 2010. The Management, recalling that planning issues are not in the remit of the SCC, underlined that this ratio concerning staff contracts is indeed the result of an analysis in the Divisions and, in any case, is considered as a guidel...

Early reflection energy in concert halls: how much, how early, and from where (A)

DEFF Research Database (Denmark)

Gade, Anders Christian

2001-01-01

Today, the importance of distributing early reflection energy to listeners and performers in concert halls is well understood and accepted—also among architects. Still, implementation in the practical design of a large hall is not easy, partly because we still have difficulties quantifying...... to decide how far to promote the good cause on the basis of his/her experience, taste, and talent in influencing the decision process. The aural presentation will focus on the current limitations in our knowledge regarding the musicians' need for early reflections, which is a special challenge in the design...

"Posh Music Should Equal Posh Dress": An Investigation into the Concert Dress and Physical Appearance of Female Soloists

Science.gov (United States)

Griffiths, Noola K.

2010-01-01

This study investigates the effects of concert dress and physical appearance on perceptions of female classical soloists' musical abilities over a range of genres. Four female violinists were recorded playing three pieces, in four styles of dress of varying formality. Each combination of performer, piece and dress was recorded twice, once as the…

Flexibility Matters: Cooperative Active Sites in Covalent Organic Framework and Threaded Ionic Polymer.

Science.gov (United States)

Sun, Qi; Aguila, Briana; Perman, Jason; Nguyen, Nicholas; Ma, Shengqian

2016-12-07

The combination of two or more reactive centers working in concert on a substrate to facilitate the reaction is now considered state of the art in catalysis, yet there still remains a tremendous challenge. Few heterogeneous systems of this sort have been exploited, as the active sites spatially separated within the rigid framework are usually difficult to cooperate. It is now shown that this roadblock can be surpassed. The underlying principle of the strategy presented here is the integration of catalytic components with excellent flexibility and porous heterogeneous catalysts, as demonstrated by the placement of linear ionic polymers in close proximity to surface Lewis acid active sites anchored on the walls of a covalent organic framework (COF). Using the cycloaddition of the epoxides and CO 2 as a model reaction, dramatic activity improvements have been achieved for the composite catalysts in relation to the individual catalytic component. Furthermore, they also clearly outperform the benchmark catalytic systems formed by the combination of the molecular organocatalysts and heterogeneous Lewis acid catalysts, while affording additional recyclability. The extraordinary flexibility and enriched concentration of the catalytically active moieties on linear polymers facilitate the concerted catalysis, thus leading to superior catalytic performance. This work therefore uncovers an entirely new strategy for designing bifunctional catalysts with double-activation behavior and opens a new avenue in the design of multicapable systems that mimic biocatalysis.

The Concert of Europe and Great Power Governance Today: What Can the Order of 19th-Century Europe Teach Policymakers About International Order in the 21st Century

Science.gov (United States)

2017-01-01

13 These differences became alarmingly clear once liberal revolutions broke out across multiple European polities in 1820.61 The eastern powers ...dealings with that eastern power that they had so often worked with in concert. For in that treat- ment, the western powers ultimately “ broke the first...KYLE LASCURETTES The Concert of Europe and Great- Power Governance Today What Can the Order of 19th-Century Europe Teach Policymakers About

Computational Investigation of the Competition between the Concerted Diels-Alder Reaction and Formation of Diradicals in Reactions of Acrylonitrile with Non-Polar Dienes

Science.gov (United States)

James, Natalie C.; Um, Joann M.; Padias, Anne B.; Hall, H. K.; Houk, K. N.

2013-01-01

The energetics of the Diels-Alder cycloaddition reactions of several 1,3-dienes with acrylonitrile, and the energetics of formation of diradicals, were investigated with density functional theory (B3LYP and M06-2X) and compared to experimental data. For the reaction of 2,3-dimethyl-1,3-butadiene with acrylonitrile, the concerted reaction is favored over the diradical pathway by 2.5 kcal/mol using B3LYP/6-31G(d); experimentally this reaction gives both cycloadduct and copolymer. The concerted cycloaddition of cyclopentadiene with acrylonitrile is preferred computationally over the stepwise pathway by 5.9 kcal/mol; experimentally, only the Diels-Alder adduct is formed. For the reactions of (E)-1,3-pentadiene and acrylonitrile, both cycloaddition and copolymerization were observed experimentally; these trends were mimicked by the computational results, which showed only a 1.2 kcal/mol preference for the concerted pathway. For the reactions of (Z)-1,3-pentadiene and acrylonitrile, the stepwise pathway is preferred by 3.9 kcal/mol, in agreement with previous experimental findings that only polymerization occurs. M06-2X is known to give more accurate activation and reaction energetics but the energies of diradicals are too high. PMID:23758325

COELIAC DISEASE IN CENTRAL AND SOUTH AMERICA: time for a concerted approach to its epidemiology

Directory of Open Access Journals (Sweden)

Affifa FARRUKH

2015-06-01

Full Text Available Central and South America offer an opportunity to resolve some of the current controversies that surround the epidemiology of celiac disease. Through a concerted action which brings together clinicians, researchers and patients there is an opportunity to establish robust data sets which will allow detailed analysis of environmental and genetic factors. In this review available data from the continent together with data from Spain and Italy are drawn together to give a current picture in the hope that it will stimulate further research.

Ventilating plant in the large concert hall of the music centre at Vredenburg/Utrecht, Holland

Energy Technology Data Exchange (ETDEWEB)

Brockmeyer, H.; Detzer, R.; van Dijk, A.E.; Kouffeld, R.W.J.

1979-01-01

To form an opinion on the thermo-dynamic and flow-pattern conditions in large halls for air conditioning like e.g. concert halls, one will refer to the study of models which normally are prepared in a reduced scale. Comparisons between model studies and the executed object indicate that, even with difficult boundary conditions, reproducible data can be prepared the deviations being only minute. Presented are the results of a model study and the data of the executed plant of a large music centre in the Netherlands.

CONCERT. ''European joint programme for the integration of radiation protection research''

International Nuclear Information System (INIS)

Schmitt-Hannig, A.; Birschwilks, M.; Jung, T.

2016-01-01

CONCERT is a joint project of the EU and its member states which assume joint financing: Over the next five years the largest European radiation protection programme so far will have available about 28 Million Euros for research and integrative measures, whereby the European Commission will bear 70 per cent of the costs. Integrative measures include, among others, targeted vocational education and training of junior researchers in radiation protection, better access to research and irradiation facilities for scientists, as well as a stronger connection of universities and research centres in radiation protection research.

L’identité des hôpitaux à partir de leurs sites Internet

Directory of Open Access Journals (Sweden)

Ahmed Dammak

2011-04-01

Full Text Available À travers l’analyse qualitative de sites Internet, les auteurs cherchent à comprendre l’évolution de l’identité des hôpitaux. Devant la difficulté conceptuelle du terme d’identité, souvent galvaudé, ils proposent une nouvelle grille de lecture de l’identité territoriale autour d’un triptyque : imaginaire, imagerie, image. Ils mettent en évidence l’importance d’une identité territoriale de l'hôpital qui se structure tant bien que mal autour de trois imaginaires : un imaginaire républicain contesté ; un imaginaire du soin oscillant entre une vision traditionnelle et une logique de service ; enfin une déterritorialisation de l’identité mettant l’hôpital en dehors de la sphère du soin.The identity of French hospitals through their websitesThrough a qualitative study of websites, the authors seek to understand the evolution of the identity of French hospitals. Considering the difficulty to define the concept of identity, they propose a new interpretative framework of territorial identity around a triptych: imaginary, imaging, and image. They highlight the importance of territorial identity of the hospital structured by three imaginary: first a republican imaginary that is challenged; secondly an imaginary of care, between traditional vision and logic of service; and finally a deterritorialization of traditional identity, so that hospital is out of the world of care.La identidad de los hospitales según sus escaparates en la redA partir del análisis cualitativo de los lugares de la red, los autores intentan aprehender la evolución de la identidad de los hospitales. Frente a la dificultad conceptual del termino tan manido de “identidad”, los autores proponen un nuevo panel de análisis de la identidad territorial a partir de un tríptico: imaginario, imaginaría e imagen. Resaltan la importancia de una identidad territorial del hospital a su vez construida laboriosamente a partir de tres imaginarios: un

Les nouvelles formes de la communication autour des projets urbains : modalités, impacts, enjeux pour un débat participatif

Directory of Open Access Journals (Sweden)

Hélène Bailleul

2008-09-01

Full Text Available Dans cet article, nous observons les évolutions que l’usage des nouvelles technologies implique dans la communication autour des projets urbains. Notre analyse des nouvelles modalités qu’Internet a pu importer dans la participation des habitants aux projets urbains (partie 1 nous pousse à observer, plus spécifiquement, les modifications qui ont trait, dans ce contexte, à la nature et au statut de l’information sur l’espace. La démocratisation des techniques de représentation de l’espace par ordinateur (3D, simulation entraîne le recours quasi systématique à des images virtuelles du projet, d’une grande qualité (partie 2, mais dont on ne connaît que très peu les impacts sur la perception et la réception que les habitants font du projet (partie 3.In this article, we observe the evolutions involved by the use of new technology in the communication around urban projects. Our analysis of the new modalities, Internet was able to import in the participation of inhabitants in urban projects (chapter 1 urges us to examine, more specifically, the modifications concerning the nature and the status of the information about space. The democratization of computer-based spatial representation’s tools (3D, simulation entails more and more systematic recourse to virtual images of the project, with high definition (chapter 2. But, nowadays, we still know little about their impacts on the perception and the reception, the inhabitants make of the project (chapter 3.

Evolutionary and polymorphism analyses reveal the central role of BTN3A2 in the concerted evolution of the BTN3 gene family.

Science.gov (United States)

Afrache, Hassnae; Pontarotti, Pierre; Abi-Rached, Laurent; Olive, Daniel

2017-06-01

The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. In order to understand how these genes have been diversified, we studied their evolution and show that the three human BTN3 are the result of two successive duplications in Primates and that the three genes are present in Hominoids and the Old World Monkey groups. A thorough phylogenetic analysis reveals a concerted evolution of BTN3 characterized by a strong and recurrent homogenization of the region encoding the signal peptide and the immunoglobulin variable (IgV) domain in Hominoids, where the sequences of BTN3A1 or BTN3A3 are replaced by BTN3A2 sequence. In human, the analysis of the diversity of these genes in 1683 individuals representing 26 worldwide populations shows that the three genes are polymorphic, with more than 46 alleles for each gene, and marked by extreme homogenization of the IgV sequences. The same analysis performed for the BTN2 genes shows also a concerted evolution; however, it is not as strong and recurrent as for BTN3. This study shows that BTN3 receptors are marked by extreme concerted evolution at the IgV domain and that BTN3A2 plays a central role in this evolution.

Offshore Wind Energy Ready to Power a Sustainable Europe. Final Report. Concerted Action on Offshore Wind Energy in Europe

International Nuclear Information System (INIS)

2001-12-01

The objective of the project Concerted Action on Offshore Wind Energy in Europe [CA-OWEE] is to define the current state of the art of offshore wind energy in Europe through gathering and evaluation of information from across Europe and to disseminate the resulting knowledge to all interested, in order to help stimulate the development of the industry. The project is being funded by the European Commission and will be completed at the end of 2001. The knowledge gathered will be freely available through an internet site, a workshop and a printed report. This project divides offshore wind energy into five clusters of subjects and reviews the recent history and summarise the current state of affairs, relating to: Cluster 1 offshore technology, of the wind turbines and the support structures, Cluster 2 grid integration, energy supply and financing, Cluster 3 resources and economics, Cluster 4 activities and prospects, Cluster 5 social acceptance, environmental impact and politics. The conclusions from these surveys are then used to define recommendations for the future RTD strategy for Europe. The project's 17 partners come from 13 countries, thus covering the majority of the European Community's coastline. The partners cover a wide range of expertise and include developers, utilities, consultants, research institutes and universities

[A concertation experience: prevention of WMSDs in workmanship of Parmigiano-Reggiano].

Science.gov (United States)

Zecchi, G

2012-01-01

The dairy industry of Parmigiano-Reggiano represents in Emilia a resource and an important source of employment. A Protected Designation of Origin (DOP) regulates all stages of processing of milk into cheese "forms" in excess of 40 kg weight, favouring a "traditional" working which involves various manual steps tiring and stressful. From 2002 to 2008 the Service in charge of the Azienda USL of Reggio Emilia has developed a plan focused on musculoskeletal risks in this sector. The need for comparison on the conservation "craftsmanship" of the complex manufacturing process maintaining high attention to health and safety brought the AUSL of Reggio E. and later the AUSL of Modena and Parma, to choose the path of concertation with the social partners, aiming at substantial and non-formal application of the law. It is thus obtained the adoption of preventive measures in a sector so peculiar, complex and constantly changing. Conciliation remains privileged tool in relations between social partners and AUSL of Reggio E. in dairies.

SPECIFIC FEATURES OF THE MUSICAL LANGUAGE AND TEXTURE IN THE CONCERT WALTZ FOR TWO PIANOS BY OLEG NEGRUTA

Directory of Open Access Journals (Sweden)

MAMALÂGA MARINA

2017-06-01

Full Text Available The article analyzes the Concert Waltz by Oleg Negruta written for piano duet. This work is considered in terms of form and content. Special attention is given to identifying the specificity of the musical language and texture. As a result, the conclusion is that the originality of the composer’s style is manifested in bright melody, relying on the classic-romantic harmony, enriched by jazz elements.

Epigenetic silencing of BTB and CNC homology 2 and concerted promoter CpG methylation in gastric cancer.

Science.gov (United States)

Haam, Keeok; Kim, Hee-Jin; Lee, Kyung-Tae; Kim, Jeong-Hwan; Kim, Mirang; Kim, Seon-Young; Noh, Seung-Moo; Song, Kyu-Sang; Kim, Yong Sung

2014-09-01

BTB and CNC homology 2 (BACH2) is a lymphoid-specific transcription factor with a prominent role in B-cell development. Genetic polymorphisms within a single locus encoding BACH2 are associated with various autoimmune diseases and allergies. In this study, restriction landmark genomic scanning revealed methylation at a NotI site in a CpG island covering the BACH2 promoter in gastric cancer cell lines and primary gastric tumors. Increased methylation of the BACH2 promoter was observed in 52% (43/83) of primary gastric tumors, and BACH2 hypermethylation was significantly associated with decreased gene expression. Treatment with 5-aza-2'-deoxycytidine and/or trichostatin. A restored BACH2 expression in BACH2-silenced gastric cancer cell lines, and knockdown of BACH2 using short hairpin RNA (i.e. RNA interference) increased cell proliferation in gastric cancer cells. Clinicopathologic data showed that decreased BACH2 expression occurred significantly more frequently in intestinal-type (27/44, 61%) compared with diffuse-type (13/50, 26%) gastric cancers (P<0.001). Furthermore, BACH2 promoter methylation paralleled that of previously identified targets, such as LRRC3B, LIMS2, PRKD1 and POPDC3, in a given set of gastric tumors. We propose that concerted methylation in many promoters plays a role in accelerating gastric tumor formation and that methylated promoter loci may be targets for therapeutic treatment, such as the recently introduced technique of epigenetic editing. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Diffusion along and around dislocations; Diffusion le long et autour des dislocations

Energy Technology Data Exchange (ETDEWEB)

Brebec, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1965-07-01

la forme, supposee cylindrique, de la region perturbee autour d'une dislocation. Il s'ensuit que l'equation de Fick est utilisee sous la forme: {partial_derivative}C/{partial_derivative}t=D[{partial_derivative}{sup 2}C/{partial_derivative}r{sup 2}+1/r{partial_derivative}C/{partial_derivative}r+{partial_derivative}{sup 2}C/{partial_derivative}z{sup 2}] pour pouvoir exprimer simplement les conditions aux limites et pour que la solution rende compte de la symetrie de revolution du systeme. Ceci complique beaucoup la forme finale des resultats. Nous donnons a titre indicatif, une solution obtenue en partant des memes hypotheses, et en faisant les memes approximations que celles utilisees par WHIPPLE dans son etude du joint de grain. Malheureusement la forme finale est impropre au calcul numerique. En faisant des approximations plus larges, equivalentes a celles de FISHER, nous pouvons determiner le parametre D/(a{sup 2}D'): on retrouve le meme resultat que pour le joint a savoir que le logarithme de la concentration moyenne varie lineairement avec la penetration, la pente de cette droite est proportionnelle a {radical}(D/(a{sup 2}D')) Enfin nous donnons la solution exacte relative a une feuille d'epaisseur finie en supposant que la diffusion dans le bon cristal est negligeable et que la diffusion superficielle est infiniment rapide. C'est le probleme traite par HENDRICKSON et MACHLIN. Nous arrivons a des conclusions differentes de celles obtenues par ces deux auteurs. (auteur)

Concerted practice and/or conscious parallelism on an oligopolistic market

Directory of Open Access Journals (Sweden)

Đuričić Jovana

2011-01-01

Full Text Available The competition represents a desirable state of the market in every society. Putting a lot of effort in trying to be better than each other, the competitors of the market, where there is a fair competition, contribute to making that market more advanced than the other one with the weaker competition. However it has become quite frequent to come across the violation of the competition in modern society. It is usually done by making different agreements or with explicit or tacit coordination of conduct on the market. Apart from these, there are many other ways for doing so, with the aim of getting certain benefits, especially making extra profit. In addition to that, there are some restrictions on the competition on oligopolistic markets too, yet, those markets are covered with different market forms which cannot be easily distinguished from the forbidden ones. This paper defines the relation between the concerted practice and conscious parallelism on an oligopolistic market, which is the example of a restricted market conduct, and the one which just seems to be legal, according to the practice of the European Court of Justice.

Analyse pragma-énonciative des s/citations du site d’Arrêt sur images A pragma-enunciative analysis of quotations on the Web site Arrêt sur images (Freeze-frame

Directory of Open Access Journals (Sweden)

Alain Rabatel

2010-04-01

Full Text Available Cet article analyse différentes formes de citations dans les sites de presse sur le WEB, en prenant comme exemple le site d’Arrêt sur images. Après avoir analysé les deux grandes catégories d’enchâssements énonciatifs à l’œuvre sur le site et dégagé quelques spécificités du discours représenté/montré et du discours d’escorte qui commente le précédent, l’article montre que le discours d’escorte joue un rôle argumentatif majeur dans la mesure où il fait plus qu’inciter le lecteur à faire apparaître les citations, il les présente comme des éléments de preuve, bref, comme des citations à faire comparaître. La fonction rhétorico-argumentative de ces citations est confirmée par le procédé du montage, qui démonte les situations servant de support à une démonstration basée sur des preuves. Enfin, compte tenu du caractère médiacritique du site, le discours d’escorte construit un ethos de professionnalisme exigeant et une communauté discursive et interprétative soudée autour de valeurs partagées.This article analyzes different forms of quotation on Web press sites, using the site Arrêt sur images as an example. After analyzing the two large categories of enunciative embeddings at work on the site and identifying the marks of direct represented/shown discourse and accompanying discourse, it shows that accompanying discourse plays a major argumentative role in so far as it does more than incite the reader to display the quotations, it presents them as elements of proof, in short, as quotations to be summoned. The rhetoric-argumentative function of quotations is confirmed through the process of editing, which dissects the situation while serving as a support to demonstration. This editing rests on a circular logic of justification based on proof. At last, considering the media critical character of the site, the accompanying discourse constructs an ethos of demanding professionalism and a united

Sud du Sahara | Page 10 | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

Nakacho was one of just a handful of women at this artisanal mining site who had managed to break away from the roles generally ascribed to her gender to become a ... Trouver un juste équilibre entre s'occuper des enfants et générer des revenus est un problème auquel sont confrontées les mères autour du monde.

Concerted evolution rapidly eliminates sequence variation in rDNA coding regions but not in intergenic spacers in Nicotiana tabacum allotetraploid

Czech Academy of Sciences Publication Activity Database

Lunerová Bedřichová, Jana; Renny-Byfield, S.; Matyášek, Roman; Leitch, A.; Kovařík, Aleš

2017-01-01

Roč. 303, č. 8 (2017), s. 1043-1060 ISSN 0378-2697 R&D Projects: GA ČR(CZ) GA17-11642S; GA ČR(CZ) GC16-02149J Institutional support: RVO:68081707 Keywords : Concerted evolution * Immunomodulation * Neutrophils Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Genetics and heredity (medical genetics to be 3) Impact factor: 1.239, year: 2016

Standing Concertation Committee - Meetings held on 6, 20 & 22 May 2008

CERN Multimedia

HR Department

2008-01-01

The main items discussed at the meeting of the Standing Concertation Committee on 6 May 2008 included: Carry-forward of leave The Committee discussed a proposal to increase, for the period 2008-2009, the carry forward of leave days at the end of the 2008 leave year (30 September 2008) so that staff members working on LHC installation and commissioning do not lose leave. It was agreed that departments would be consulted before finalizing a proposal on the number of extra days of carry-forward. Revision of CHIS Rules The Committee discussed a number of outstanding issues relating to the current revision of the CHIS Rules. This revision should be finalized before a market survey is launched for the service contract for the administration of the CHIS that is foreseen by the end of the year. Preparation for TREF on 28 May The following items were to be discussed at TREF on 28 May 2008: Equal Opportunities Report The Committee took note of the report for 2007 presented by the Equ...

An European concerted action investigating the validity of perinatal mortality as an outcome indicator for the quality of antenatal and perinatal care

NARCIS (Netherlands)

Richardus, J.H.; Graafmans, W.C.; Pal-de Bruin, K.M. van der; Amelink-Verburg, M.P.; Verloove-Vanhorick, S.P.; Mackenbach, J.P.

1997-01-01

In this paper the concepts, objectives, design, and data analysis procedures of the EuroNatal study are described. This sutdy started in 1996 and is a concerted action including 14 countries in Europe. The EuroNatal study aims at determining the validity of national perinatal mortality rates as an

State-of-the-art research: Reflections on a concerted Nordic-Baltic nuclear energy effort

Energy Technology Data Exchange (ETDEWEB)

Husdal, Lars; Tveit, Jesper; Vaagen, Jan S; Ridikas, Danas

2009-09-15

Quite a few hold the view that nuclear energy will have its renaissance in the not too distant future. Technology is, however, a necessary, but not sufficient condition. The needed prerequisites represent a complex issue. With increasing energy demand and depletion of non-renewable energy resources, nuclear will have to prove its role in an increasing energy mix, globally, regionally and often also nationally. Based on its history, experience with coordinated interplay in electricity production from a variety of energy sources, and science engagements, we argue for a future Nordic/Baltic SHOWCASE: A nuclear weapons free and proliferation safe nuclear energy supplier in the region, with a concerted role in competence building and in international ventures, and with focus on operation, safety, economy and societal aspects. (Author)

Music Audiences 3.0: Concert-Goers’ Psychological Motivations at the Dawn of Virtual Reality

Directory of Open Access Journals (Sweden)

Jean-Philippe Charron

2017-05-01

Full Text Available Reviewing consumers’ motivations to attend performances in a continuously evolving social and technological context is essential because live concerts generate an important and growing share of revenues for the music industry. Evolving fans’ preferences and technological innovations constantly alter the way music is distributed and consumed. In a marketing 3.0 era, what consumers do with music is becoming more significant than simply owning or listening to a song. These changes are not only blurring the lines between production and consumption (i.e., co-creation, but also distorting the concept of live attendance altogether. Although mediated performances typically lack presence and authenticity, recent advances in immersive technologies, such as spherical videos and virtual reality goggles, could represent a new form of experiencing live music.

Music Audiences 3.0: Concert-Goers' Psychological Motivations at the Dawn of Virtual Reality.

Science.gov (United States)

Charron, Jean-Philippe

2017-01-01

Reviewing consumers' motivations to attend performances in a continuously evolving social and technological context is essential because live concerts generate an important and growing share of revenues for the music industry. Evolving fans' preferences and technological innovations constantly alter the way music is distributed and consumed. In a marketing 3.0 era, what consumers do with music is becoming more significant than simply owning or listening to a song. These changes are not only blurring the lines between production and consumption (i.e., co-creation), but also distorting the concept of live attendance altogether. Although mediated performances typically lack presence and authenticity, recent advances in immersive technologies, such as spherical videos and virtual reality goggles, could represent a new form of experiencing live music.

Music Audiences 3.0: Concert-Goers’ Psychological Motivations at the Dawn of Virtual Reality

Science.gov (United States)

Charron, Jean-Philippe

2017-01-01

Reviewing consumers’ motivations to attend performances in a continuously evolving social and technological context is essential because live concerts generate an important and growing share of revenues for the music industry. Evolving fans’ preferences and technological innovations constantly alter the way music is distributed and consumed. In a marketing 3.0 era, what consumers do with music is becoming more significant than simply owning or listening to a song. These changes are not only blurring the lines between production and consumption (i.e., co-creation), but also distorting the concept of live attendance altogether. Although mediated performances typically lack presence and authenticity, recent advances in immersive technologies, such as spherical videos and virtual reality goggles, could represent a new form of experiencing live music. PMID:28588528

State-of-the-art research: Reflections on a concerted Nordic-Baltic nuclear energy effort

International Nuclear Information System (INIS)

Husdal, Lars; Tveit, Jesper; Vaagen, Jan S.; Ridikas, Danas

2009-09-01

Quite a few hold the view that nuclear energy will have its renaissance in the not too distant future. Technology is, however, a necessary, but not sufficient condition. The needed prerequisites represent a complex issue. With increasing energy demand and depletion of non-renewable energy resources, nuclear will have to prove its role in an increasing energy mix, globally, regionally and often also nationally. Based on its history, experience with coordinated interplay in electricity production from a variety of energy sources, and science engagements, we argue for a future Nordic/Baltic SHOWCASE: A nuclear weapons free and proliferation safe nuclear energy supplier in the region, with a concerted role in competence building and in international ventures, and with focus on operation, safety, economy and societal aspects. (Author)

Geologic CO₂ Sequestration Potential of 42 California Power Plant Sites: A Status Report to WESTCARB

Energy Technology Data Exchange (ETDEWEB)

Myers, Katherine B.L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wagoner, J. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2011-06-15

Forty-two California natural gas combined-cycle (NGCC) power plant sites were evaluated for geologic carbon dioxide (CO₂) sequestration potential. The following data were collected in order to gauge the sequestration potential of each power plant site: nearest potential CO₂ sink, proximity to oil or gas fi elds, subsurface geology, surface expression of nearby faults, and subsurface water. The data for each site were compiled into a one-page, standalone profi le to serve as a quick reference for future decision-makers. A subset of these data was compiled into a summary table for easy comparison of all 42 sites. Decision-makers will consider the geologic CO₂ sequestration potential of each power plant in concert with its CO₂ capture potential and will select the most suitable sites for a future carbon capture and storage project. Once the most promising sites are selected, Lawrence Livermore National Laboratory (LLNL) will conduct additional geologic research in order to construct a detailed 3D geologic model for those sites.

Parametrization in models of subcritical glass fracture: Activation offset and concerted activation

Science.gov (United States)

Rodrigues, Bruno Poletto; Hühn, Carolin; Erlebach, Andreas; Mey, Dorothea; Sierka, Marek; Wondraczek, Lothar

2017-08-01

There are two established but fundamentally different empirical approaches to parametrize the rate of subcritical fracture in brittle materials. While both are relying on a thermally activated reaction of bond rupture, the difference lies in the way as to how the externally applied stresses affect the local energy landscape. In the consideration of inorganic glasses, the strain energy is typically taken as an off-set on the activation barrier. As an alternative interpretation, the system’s volumetric strain-energy is added to its thermal energy. Such an interpretation is consistent with the democratic fiber bundle model. Here, we test this approach of concerted activation against macroscopic data of bond cleavage activation energy, and also against ab initio quantum chemical simulation of the energy barrier for cracking in silica. The fact that both models are able to reproduce experimental observation to a remarkable degree highlights the importance of a holistic consideration towards non-empirical understanding.

Concerted Practice-Based Actions in Intimate Partner and Family Violence: When the Children’s Well-Being Is the Central Concern

Directory of Open Access Journals (Sweden)

Geneviève Lessard

2014-09-01

Full Text Available In Canada, the exposure of children to intimate partner violence is, along with negligence, one of the most frequent forms of maltreatment. Intimate partner violence raises important issues with regard to child custody and to the exercising of parental roles. The aid provided for children exposed to intimate partner violence covers a range of programs, in particular community services specializing in intimate partner violence, frontline social and health services, and child protection. However, these resource services do not share the same missions, or the same understanding of the problems and possible solutions, since they often operate in parallel networks. The complex situations of families confronted with intimate partner violence present considerable challenges in terms of collaboration between the different organizations. Action research was employed to develop an innovative concertation strategy that fostered collaboration between practitioners from different family resource services. The strategy, which was implemented in the Québec City region between 2011 and 2013, was then evaluated. This article presents the results of this evaluation as well as the positive outcomes that the concertation strategy had for the practitioners’ practice and for the improvement of family services.

A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.

Directory of Open Access Journals (Sweden)

Annie Demers

2009-11-01

Full Text Available The peroxisome proliferator-activator receptor PPARgamma plays an essential role in vascular biology, modulating macrophage function and atherosclerosis progression. Recently, we have described the beneficial effect of combined activation of the ghrelin/GHS-R1a receptor and the scavenger receptor CD36 to induce macrophage cholesterol release through transcriptional activation of PPARgamma. Although the interplay between CD36 and PPARgamma in atherogenesis is well recognized, the contribution of the ghrelin receptor to regulate PPARgamma remains unknown. Here, we demonstrate that ghrelin triggers PPARgamma activation through a concerted signaling cascade involving Erk1/2 and Akt kinases, resulting in enhanced expression of downstream effectors LXRalpha and ABC sterol transporters in human macrophages. These effects were associated with enhanced PPARgamma phosphorylation independently of the inhibitory conserved serine-84. Src tyrosine kinase Fyn was identified as being recruited to GHS-R1a in response to ghrelin, but failure of activated Fyn to enhance PPARgamma Ser-84 specific phosphorylation relied on the concomitant recruitment of docking protein Dok-1, which prevented optimal activation of the Erk1/2 pathway. Also, substitution of Ser-84 preserved the ghrelin-induced PPARgamma activity and responsiveness to Src inhibition, supporting a mechanism independent of Ser-84 in PPARgamma response to ghrelin. Consistent with this, we found that ghrelin promoted the PI3-K/Akt pathway in a Galphaq-dependent manner, resulting in Akt recruitment to PPARgamma, enhanced PPARgamma phosphorylation and activation independently of Ser-84, and increased expression of LXRalpha and ABCA1/G1. Collectively, these results illustrate a complex interplay involving Fyn/Dok-1/Erk and Galphaq/PI3-K/Akt pathways to transduce in a concerted manner responsiveness of PPARgamma to ghrelin in macrophages.

Operational Circular No. 2 (Rev. 3) - Conditions of access to the fenced parts of the CERN site

CERN Multimedia

HR Department

2015-01-01

Operational Circular No. 2 (Rev. 3) entitled "Conditions of access to the fenced parts of the CERN site", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 24 September 2015, is now available via this link.   This revised circular cancels and replaces Operational Circular No. 2 (Rev. 2) also entitled "Conditions of access to the fenced parts of the CERN site", of September 2014. The circular was revised predominantly in order to specify that access to the CERN site is granted to CERN Pension Fund beneficiaries only provided that they are actually in receipt of payments from the Fund; and to allow the Director-General to permit special types of vehicles on site, such as trailers. It also includes a certain number of text improvements and an updated version of the implementation measures, in particular with regard to vehicle identification, road traffic and parking.  

An analysis of concert saxophone vibrato through the examination of recordings by eight prominent soloists

Science.gov (United States)

Zinninger, Thomas

This study examines concert saxophone vibrato through the analysis of several recordings of standard repertoire by prominent soloists. The vibrato of Vincent Abato, Arno Bornkamp, Claude Delangle, Jean-Marie Londeix, Marcel Mule, Otis Murphy, Sigurd Rascher, and Eugene Rousseau is analyzed with regards to rate, extent, shape, and discretionary use. Examination of these parameters was conducted through both general observation and precise measurements with the aid of a spectrogram. Statistical analyses of the results provide tendencies for overall vibrato use, as well as the effects of certain musical attributes (note length, tempo, dynamic, range) on vibrato. The results of this analysis are also compared among each soloist and against pre-existing theories or findings in vibrato research.

The 5S rDNA family evolves through concerted and birth-and-death evolution in fish genomes: an example from freshwater stingrays

Science.gov (United States)

2011-01-01

Background Ribosomal 5S genes are well known for the critical role they play in ribosome folding and functionality. These genes are thought to evolve in a concerted fashion, with high rates of homogenization of gene copies. However, the majority of previous analyses regarding the evolutionary process of rDNA repeats were conducted in invertebrates and plants. Studies have also been conducted on vertebrates, but these analyses were usually restricted to the 18S, 5.8S and 28S rRNA genes. The recent identification of divergent 5S rRNA gene paralogs in the genomes of elasmobranches and teleost fishes indicate that the eukaryotic 5S rRNA gene family has a more complex genomic organization than previously thought. The availability of new sequence data from lower vertebrates such as teleosts and elasmobranches enables an enhanced evolutionary characterization of 5S rDNA among vertebrates. Results We identified two variant classes of 5S rDNA sequences in the genomes of Potamotrygonidae stingrays, similar to the genomes of other vertebrates. One class of 5S rRNA genes was shared only by elasmobranches. A broad comparative survey among 100 vertebrate species suggests that the 5S rRNA gene variants in fishes originated from rounds of genome duplication. These variants were then maintained or eliminated by birth-and-death mechanisms, under intense purifying selection. Clustered multiple copies of 5S rDNA variants could have arisen due to unequal crossing over mechanisms. Simultaneously, the distinct genome clusters were independently homogenized, resulting in the maintenance of clusters of highly similar repeats through concerted evolution. Conclusions We believe that 5S rDNA molecular evolution in fish genomes is driven by a mixed mechanism that integrates birth-and-death and concerted evolution. PMID:21627815

The Role of MOR and the CI Operator Sites on the Genetic Switch of the Temperate Bacteriophage TP901-1

DEFF Research Database (Denmark)

Pedersen, Margit; Hammer, Karin

2008-01-01

. The cloned DNA fragment contained the two divergently oriented promoters, P-R and P-L, transcribing the lysogenic and lytic gene clusters; the two promoter-. proximal genes, cl and mor; and the three CI operator sites, O-R, O-L and O-D. We show that mor encodes a protein and that this protein in concert......-D) is enough to maintain a bistable system. The distantly located operator site, 01:), functions as a helper site by increasing binding of CI at O-R and O-L. In the immune state, O-D increases repression of the lytic promoter, P-L. Our results strongly support the model that a hexameric form of Cl binds...... cooperatively to the three operator sites in the immune state forming a CI-DNA loop structure. Finally, we show that in the anti-immune state, repression of the lysogenic promoter is independent of the known CI operator sites but requires the presence of both CI and MOR....

Candidate reagents and procedures for the dissolution of Hanford Site single-shell tank sludges

International Nuclear Information System (INIS)

Schulz, W.W.; Kupfer, M.J.

1991-10-01

At least some of the waste in the 149 single-shell tanks (SST) at the US Department of Energy (DOE) Hanford Site will be retrieved, treated, and disposed of. Although the importance of devising efficient and cost-effective sludge dissolution procedures has long been recognized, a concerted bench-scale effort to devise and test such procedures with actual solids representative of those in Hanford Site SSTs has not been performed. Reagents that might be used, either individually or serially, to dissolve sludges include HNO 3 , HNO 3 -oxalic acid, and HNO 3 -HF. This report consolidates and updates perspectives and recommendations concerning reagents and procedures for dissolving Hanford Site SST and selected double-shell tank (DST) sludges. The principal objectives of this report are as follows: (1) Compile and review existing experimental data on dissolution of actual Hanford Site SST and DST sludges. (2) Further inform Hanford Site engineers and scientists concerning the utility of combinations of thermally unstable complexants (TUCS) reagents and various reducing agents for dissolving SST and DST sludges. (This latter technology has recently been explored at the Argonne National Laboratory.) (3) Provide guidance in laying out a comprehensive experimental program to develop technology for dissolving all types of Hanford Site SST and DST sludges. 6 refs., 1 fig., 4 tabs

Music and politics after the Holocaust: Menuhin’s Berlin concerts of 1947 and their aftermath

Directory of Open Access Journals (Sweden)

Frühauf, Tina

2011-10-01

Full Text Available Between September 27 and October 3, 1947, Yehudi Menuhin gave six performances in Berlin, two of them together with Wilhelm Furtwängler, who had just been cleared by the denazification tribunals in Austria and Germany. Because of the German audience and the Furtwängler collaboration, these concerts led to a scandal in the Jewish community and the Displaced Persons camp in Germany as well as Jewish communities abroad. I turn first to the historical background of these performances, specifically the position of Menuhin and Furtwängler toward each other and their roles in postwar Germany. I will then chronicle the events of September and October 1947 through the lenses of Abraham S. Hyman, legal consultant to the American Advisers on Jewish Affairs in Germany, and Yehudi Menuhin and his biographers, to reveal the complexity of the events. Lastly, I will scrutinize the reception of the concerts to shed light on the reasons for and impact of the scandal. I argue that these concerts were mishandled in their organization and aims, in that politics played too large a role in the events during a time when the Jewish people suffered severe trauma in the aftermath of the Holocaust.

Entre el 27 de septiembre y el 3 de octubre del 1947, Yehudi Menuhin ofreció seis conciertos en Berlín, dos de ellos con Wilhelm Furtwängler, quien acababa de ser declarado inocente por los tribunales de “desnazificación” en Austria y Alemania. Debido a que el público era alemán y a la participación de Furtwängler, estos conciertos provocaron un fuerte escándalo entre la comunidad judía y la población desplazada de los campos en Alemania, así como entre las comunidades judías en el extranjero. Mi investigación se centra, primero, en el contexto histórico de estos conciertos y, concretamente, la posición de Menuhin y Furtwängler hacia el uno al otro, así como sus respectivos papeles en la Alemania de la postguerra. Posteriormente ofrezco una relaci

Computations on the primary photoreaction of Br2 with CO2: stepwise vs concerted addition of Br atoms.

Science.gov (United States)

Xu, Kewei; Korter, Timothy M; Braiman, Mark S

2015-04-09

It was proposed previously that Br2-sensitized photolysis of liquid CO2 proceeds through a metastable primary photoproduct, CO2Br2. Possible mechanisms for such a photoreaction are explored here computationally. First, it is shown that the CO2Br radical is not stable in any geometry. This rules out a free-radical mechanism, for example, photochemical splitting of Br2 followed by stepwise addition of Br atoms to CO2-which in turn accounts for the lack of previously observed Br2+CO2 photochemistry in gas phases. A possible alternative mechanism in liquid phase is formation of a weakly bound CO2:Br2 complex, followed by concerted photoaddition of Br2. This hypothesis is suggested by the previously published spectroscopic detection of a binary CO2:Br2 complex in the supersonically cooled gas phase. We compute a global binding-energy minimum of -6.2 kJ mol(-1) for such complexes, in a linear geometry. Two additional local minima were computed for perpendicular (C2v) and nearly parallel asymmetric planar geometries, both with binding energies near -5.4 kJ mol(-1). In these two latter geometries, C-Br and O-Br bond distances are simultaneously in the range of 3.5-3.8 Å, that is, perhaps suitable for a concerted photoaddition under the temperature and pressure conditions where Br2 + CO2 photochemistry has been observed.

Stakeholder Analysis for Sharing Agro-environment Issues Towards Concerted Action: A Case Study on Diffuse Nitrate Pollution

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Pier Paolo Roggero

2006-12-01

Full Text Available There is increasing need for participatory approaches to support the development of sustainable farming systems, based on the active involvement of stakeholders in the definition of research objectives and priorities. This paper reports the experience of a team of agronomy researchers involved in the SLIM project (http://slim.open.ac.uk, around a case study of nitrate pollution. The agro-ecosystem analysis included biophysical processes at microcatchment scale and the stakeholders’ perceptions, interests and practices related to the nitrate issue (stakeholders analysis. The conceptual SLIM framework model supported new interactions among stakeholders, that were facilitated by researchers, using dialogical tools to enable them to use scientific data and to integrate their own knowledge on the farming system. The agro-environment policies, based on compulsory prescriptions, revealed weak assumptions and insufficient integration of scientific knowledge. The stakeholder analysis contributed to the identification of priorities both for scientific research and agro-environment policies. Researchers provided the site-specific scientific knowledge, in a way that enabled stakeholders to identify the relationships between agricultural practices, landscape values and the nitrate pollution issue and to elaborate shared strategies to develop concerted actions. New spaces for interaction between researchers and stakeholders should be created to face complex agro-environment issues at catchment scale, such as the nitrate pollution of groundwater. The implication for agronomy research is that the experiments should be designed to produce suitable results to facilitate participatory sessions and that it is worthwhile to invest in specific skills of communication science and group dynamics management within the agronomy researchers’ community, in order to integrate agronomy knowledge into high quality participatory processes.

Stakeholder Analysis for Sharing Agro-environment Issues Towards Concerted Action: A Case Study on Diffuse Nitrate Pollution

Directory of Open Access Journals (Sweden)

Marco Toderi

2011-02-01

Full Text Available There is increasing need for participatory approaches to support the development of sustainable farming systems, based on the active involvement of stakeholders in the definition of research objectives and priorities. This paper reports the experience of a team of agronomy researchers involved in the SLIM project (http://slim.open.ac.uk, around a case study of nitrate pollution. The agro-ecosystem analysis included biophysical processes at microcatchment scale and the stakeholders’ perceptions, interests and practices related to the nitrate issue (stakeholders analysis. The conceptual SLIM framework model supported new interactions among stakeholders, that were facilitated by researchers, using dialogical tools to enable them to use scientific data and to integrate their own knowledge on the farming system. The agro-environment policies, based on compulsory prescriptions, revealed weak assumptions and insufficient integration of scientific knowledge. The stakeholder analysis contributed to the identification of priorities both for scientific research and agro-environment policies. Researchers provided the site-specific scientific knowledge, in a way that enabled stakeholders to identify the relationships between agricultural practices, landscape values and the nitrate pollution issue and to elaborate shared strategies to develop concerted actions. New spaces for interaction between researchers and stakeholders should be created to face complex agro-environment issues at catchment scale, such as the nitrate pollution of groundwater. The implication for agronomy research is that the experiments should be designed to produce suitable results to facilitate participatory sessions and that it is worthwhile to invest in specific skills of communication science and group dynamics management within the agronomy researchers’ community, in order to integrate agronomy knowledge into high quality participatory processes.

Acts of the Ville d'Avray seminar on the 23. march 2004 on the dialogue around industrial sites; Actes du deuxieme seminaire de Ville d'Avray du 23 mars 2004 sur la concertation autour des sites industriels

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-09-15

In order to answer to a society demand of bigger transparency and participation to an elaboration process of decisions involving risks for health and environment was created a mission within I.R.S.N.. This technical dialogue, to build between society and I.R.S.N. is a lever that can allow at the same time to improve the quality of the Institute expertise by taking into account the society demand and information, to increase the value of its competence, to increase its reactivity and its credibility. (N.C.)

In-situ observations of young contrails – overview and selected results from the CONCERT campaign

Directory of Open Access Journals (Sweden)

C. Voigt

2010-09-01

Full Text Available Lineshaped contrails were detected with the research aircraft Falcon during the CONCERT – CONtrail and Cirrus ExpeRimenT – campaign in October/November 2008. The Falcon was equipped with a set of instruments to measure the particle size distribution, shape, extinction and chemical composition as well as trace gas mixing ratios of sulfur dioxide (SO₂, reactive nitrogen and halogen species (NO, NO_y, HNO₃, HONO, HCl, ozone (O₃ and carbon monoxide (CO. During 12 mission flights over Europe, numerous contrails, cirrus clouds and a volcanic aerosol layer were probed at altitudes between 8.5 and 11.6 km and at temperatures above 213 K. 22 contrails from 11 different aircraft were observed near and below ice saturation. The observed NO mixing ratios, ice crystal and soot number densities are compared to a process based contrail model. On 19 November 2008 the contrail from a CRJ-2 aircraft was penetrated in 10.1 km altitude at a temperature of 221 K. The contrail had mean ice crystal number densities of 125 cm⁻³ with effective radii r_eff of 2.6 μm. The presence of particles with r>50 μm in the less than 2 min old contrail suggests that natural cirrus crystals were entrained in the contrail. Mean HONO/NO (HONO/NO_y ratios of 0.037 (0.024 and the fuel sulfur conversion efficiency to H₂SO₄ (ε_S↓ of 2.9 % observed in the CRJ-2 contrail are in the range of previous measurements in the gaseous aircraft exhaust. On 31 October 2010 aviation NO emissions could have contributed by more than 40% to the regional scale NO levels in the mid-latitude lowest stratosphere. The CONCERT observations help to better quantify the climate impact from contrails and will be used to investigate the chemical processing of trace gases on contrails.

Scharoun versus Gehry : dos opciones metodológicas personales explícitas a partir del análisis de la Filarmónica de Berlín y el Walt Disney Concert Hall

Directory of Open Access Journals (Sweden)

Eneko Besa

2012-12-01

Full Text Available

Resumen

Estudio de la Filarmónica de Berlín como ejemplo de las  diferentes aproximaciones y contradicciones que la arquitectura “traba” a través del argumento que la constituye. Acuerdo tenso entre interior‐exterior, lugar‐programa, simetría‐asimetría,  unidad sintética ‐ complejidad múltiple, continuidad orgánica ‐ discontinuidad fragmentada.
Comparativa con el edificio Walt Disney Concert Hall, en el que  se utiliza la misma tipología de sala de conciertos. Sin embargo y al contrario que Scharoun, Gehry evita cualquier acuerdo sintético de unidad, constituyendo el edificio a partir de la pura  fragmentación y diversidad per se. Pues en su caso, la unidad necesaria para constituir la autonomía y ser de la obra, se buscará a través de la imagen y expresión del concepto de  belleza que el edificio alcanza.

Palabras clave

sala de conciertos, lugar, unidad, exterior, fragmento

Abstract

This article is a study of the Berlin Philharmonic Concert Hall as an example of the different approximations and contradictions that Architecture ties together as a result of the reasoning that makes it up. A tense agreement between interior and exterior, place and program, symmetry and asymmetry, synthetic unity and multiple complexity, organic continuity and fragmented discontinuity.
A comparison to Walt Disney Concert Hall is made, where the same concert hall typology is used. Nevertheless, in contrast to Scharoun, Gehry avoids any kind of synthetic agreement of unity, conceiving the building out of pure fragmentation and  diversity per se. In Gehry’s case, the unity necessary to constitute the autonomy and essence of the building is sought  through the image and expression of the concept of beauty that it reaches.

Key words

concert hall, place, unity, exterior, fragment

Rainforests as concert halls for birds: Are reverberations improving sound transmission of long song elements?

DEFF Research Database (Denmark)

Nemeth, Erwin; Dabelsteen, Torben; Pedersen, Simon Boel

2006-01-01

that longer sounds are less attenuated. The results indicate that higher sound pressure level is caused by superimposing reflections. It is suggested that this beneficial effect of reverberations explains interspecific birdsong differences in element length. Transmission paths with stronger reverberations......In forests reverberations have probably detrimental and beneficial effects on avian communication. They constrain signal discrimination by masking fast repetitive sounds and they improve signal detection by elongating sounds. This ambivalence of reflections for animal signals in forests is similar...... to the influence of reverberations on speech or music in indoor sound transmission. Since comparisons of sound fields of forests and concert halls have demonstrated that reflections can contribute in both environments a considerable part to the energy of a received sound, it is here assumed that reverberations...

Le vocabulaire de la passion amoureuse dans les tragédies de Corneille

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Vasile Rădulescu

2007-05-01

Full Text Available La tragédie française du XVII-e siècle tourne autour de la notion de passion, qui, dans la conception classique, est une agitation de l’âne humaine. Elle revêt des formes diverses : passion amoureuse, ambition, soif de pouvoir (libido dominandé, soif de vengeance, orgueil, etc.Corneille ne fait pas exception, son œuvre s’inscrit dans le concert et le consensus de l’époque, son mérite consiste à avoir mieux exprimé que d’autres les thèmes et les motifs communs. A l’aide d’un vocabulaire restreint, général, conventionnel, il réussit à éveiller des énergies insoupçonnables, qui confèrent de la grandeur à l’homme.L’ouvrage se propose de souligner les notions et le vocabulaire qui mettent en mouvement l’une des formes de la passion humaine, considérée à l’âge classique comme étant très importante : l’amour.

Distinct mechanisms act in concert to mediate cell cycle arrest.

Science.gov (United States)

Toettcher, Jared E; Loewer, Alexander; Ostheimer, Gerard J; Yaffe, Michael B; Tidor, Bruce; Lahav, Galit

2009-01-20

In response to DNA damage, cells arrest at specific stages in the cell cycle. This arrest must fulfill at least 3 requirements: it must be activated promptly; it must be sustained as long as damage is present to prevent loss of genomic information; and after the arrest, cells must re-enter into the appropriate cell cycle phase to ensure proper ploidy. Multiple molecular mechanisms capable of arresting the cell cycle have been identified in mammalian cells; however, it is unknown whether each mechanism meets all 3 requirements or whether they act together to confer specific functions to the arrest. To address this question, we integrated mathematical models describing the cell cycle and the DNA damage signaling networks and tested the contributions of each mechanism to cell cycle arrest and re-entry. Predictions from this model were then tested with quantitative experiments to identify the combined action of arrest mechanisms in irradiated cells. We find that different arrest mechanisms serve indispensable roles in the proper cellular response to DNA damage over time: p53-independent cyclin inactivation confers immediate arrest, whereas p53-dependent cyclin downregulation allows this arrest to be sustained. Additionally, p21-mediated inhibition of cyclin-dependent kinase activity is indispensable for preventing improper cell cycle re-entry and endoreduplication. This work shows that in a complex signaling network, seemingly redundant mechanisms, acting in a concerted fashion, can achieve a specific cellular outcome.

Radical Abstraction Reactions with Concerted Fragmentation in the Chain Decay of Nitroalkanes

Science.gov (United States)

Denisov, E. T.; Shestakov, A. F.

2018-05-01

Reactions of the type X• + HCR2CH2NO2 → XH + R2C=CH2 + N•O2 are exothermic, due to the breaking of weak C-N bonds and the formation of energy-intensive C=C bonds. Quantum chemistry calculations of the transition state using the reactions of Et• and EtO• with 2-nitrobutane shows that such reactions can be categorized as one-step, due to the extreme instability of the intermediate nitrobutyl radical toward decay with the formation of N•O2. Kinetic parameters that allow us to calculate the energy of activation and rate constant of such a reaction from its enthalpy are estimated using a model of intersecting parabolas. Enthalpies, energies of activation, and rate constants are calculated for a series of reactions with the participation of Et•, EtO•, RO•2, N•O2 radicals on the one hand and a series of nitroalkanes on the other. A new kinetic scheme of the chain decay of nitroalkanes with the participation of abstraction reactions with concerted fragmentation is proposed on the basis of the obtained data.

Efficacy of Role Play in Concert with Lecture to Enhance Student Learning of Immunology

Directory of Open Access Journals (Sweden)

Samantha L. Elliott

2010-11-01

Full Text Available Despite numerous reports that active learning increases student understanding, many barriers still exist that prevent faculty from shedding the traditional passive lecture and adopting active learning strategies in the classroom. This study looks at the use of role play as an active learning technique to convey new material, or as reinforcement to traditional lecture. A pre- and post-test survey was utilized to determine student learning gains, along with an anonymous survey to determine student attitudes about role play. Student learning gains are similar regardless of class size, role-playing participation or learning style, and reflect an increase in lower order cognition. Attitudes and learning gains indicate role play is preferable as a reinforcement technique, although the order does not matter if both lecture and role play are utilized to convey information. These data provide insight into the best practices of role-playing implementation in concert with traditional lecture format.

Design and evaluation of a higher-order spherical microphone/ambisonic sound reproduction system for the acoustical assessment of concert halls

Science.gov (United States)

Clapp, Samuel W.

Previous studies of the perception of concert hall acoustics have generally employed two methods for soliciting listeners' judgments. One method is to have listeners rate the sound in a hall while physically present in that hall. The other method is to make recordings of different halls and seat positions, and then recreate the environment for listeners in a laboratory setting via loudspeakers or headphones. In situ evaluations offer a completely faithful rendering of all aspects of the concert hall experience. However, many variables cannot be controlled and the short duration of auditory memory precludes an objective comparison of different spaces. Simulation studies allow for more control over various aspects of the evaluations, as well as A/B comparisons of different halls and seat positions. The drawback is that all simulation methods suffer from limitations in the accuracy of reproduction. If the accuracy of the simulation system is improved, then the advantages of the simulation method can be retained, while mitigating its disadvantages. Spherical microphone array technology has received growing interest in the acoustics community in recent years for many applications including beamforming, source localization, and other forms of three-dimensional sound field analysis. These arrays can decompose a measured sound field into its spherical harmonic components, the spherical harmonics being a set of spatial basis functions on the sphere that are derived from solving the wave equation in spherical coordinates. Ambisonics is a system for two- and three-dimensional spatialized sound that is based on recreating a sound field from its spherical harmonic components. Because of these shared mathematical underpinnings, ambisonics provides a natural way to present fully spatialized renderings of recordings made with a spherical microphone array. Many of the previously studied applications of spherical microphone arrays have used a narrow frequency range where the array

Analysis of functional importance of binding sites in the Drosophila gap gene network model.

Science.gov (United States)

Kozlov, Konstantin; Gursky, Vitaly V; Kulakovskiy, Ivan V; Dymova, Arina; Samsonova, Maria

2015-01-01

The statistical thermodynamics based approach provides a promising framework for construction of the genotype-phenotype map in many biological systems. Among important aspects of a good model connecting the DNA sequence information with that of a molecular phenotype (gene expression) is the selection of regulatory interactions and relevant transcription factor bindings sites. As the model may predict different levels of the functional importance of specific binding sites in different genomic and regulatory contexts, it is essential to formulate and study such models under different modeling assumptions. We elaborate a two-layer model for the Drosophila gap gene network and include in the model a combined set of transcription factor binding sites and concentration dependent regulatory interaction between gap genes hunchback and Kruppel. We show that the new variants of the model are more consistent in terms of gene expression predictions for various genetic constructs in comparison to previous work. We quantify the functional importance of binding sites by calculating their impact on gene expression in the model and calculate how these impacts correlate across all sites under different modeling assumptions. The assumption about the dual interaction between hb and Kr leads to the most consistent modeling results, but, on the other hand, may obscure existence of indirect interactions between binding sites in regulatory regions of distinct genes. The analysis confirms the previously formulated regulation concept of many weak binding sites working in concert. The model predicts a more or less uniform distribution of functionally important binding sites over the sets of experimentally characterized regulatory modules and other open chromatin domains.

Long-term observations of Boreal Toads at an ARMI apex site

Science.gov (United States)

Corn, Paul Stephen; Muths, Erin L.; Pilliod, David S.

2011-01-01

The U.S. Geological Survey’s Amphibian Research and Monitoring Initiative (ARMI) is a national project with goals to monitor the status and trends of amphibians, conduct research on causes of declines, and provide information and support to management agencies for conservation of amphibian populations. ARMI activities are organized around extensive inventories and place-based monitoring (such as collaboration with the Greater Yellowstone Inventory and Monitoring Network), and intensive population studies and research at selected locations (apex sites). One such site is an oxbow pond on the Buffalo Fork near the Black Rock Ranger Station east of Grand Teton National Park. We have been conducting mark-recapture of boreal toads (Anaxyrus boreas) at Black Rock since 2002. In concert with studies of other toad populations in the Rocky Mountains, we have documented a high rate of incidence of the chytrid fungus Batrachochytrium dendrobatidis (Bd) and a negative rate of growth of the toad population, but not the population crash or extinction observed in other populations with high prevalence of Bd. Long-term observations at other ARMI apex sites have proven invaluable for studying effects of climate change on amphibian behavior, and the Black Rock site has been upgraded with onsite recording of weather data and auditory monitoring of other amphibian species. Continued research at Black Rock will be critical for understanding the interrelated effects of climate and disease on amphibians in the Greater Yellowstone Ecosystem.

Concerted Uranium Research in Europe (CURE): toward a collaborative project integrating dosimetry, epidemiology and radiobiology to study the effects of occupational uranium exposure.

Science.gov (United States)

Laurent, Olivier; Gomolka, Maria; Haylock, Richard; Blanchardon, Eric; Giussani, Augusto; Atkinson, Will; Baatout, Sarah; Bingham, Derek; Cardis, Elisabeth; Hall, Janet; Tomasek, Ladislav; Ancelet, Sophie; Badie, Christophe; Bethel, Gary; Bertho, Jean-Marc; Bouet, Ségolène; Bull, Richard; Challeton-de Vathaire, Cécile; Cockerill, Rupert; Davesne, Estelle; Ebrahimian, Teni; Engels, Hilde; Gillies, Michael; Grellier, James; Grison, Stephane; Gueguen, Yann; Hornhardt, Sabine; Ibanez, Chrystelle; Kabacik, Sylwia; Kotik, Lukas; Kreuzer, Michaela; Lebacq, Anne Laure; Marsh, James; Nosske, Dietmar; O'Hagan, Jackie; Pernot, Eileen; Puncher, Matthew; Rage, Estelle; Riddell, Tony; Roy, Laurence; Samson, Eric; Souidi, Maamar; Turner, Michelle C; Zhivin, Sergey; Laurier, Dominique

2016-06-01

The potential health impacts of chronic exposures to uranium, as they occur in occupational settings, are not well characterized. Most epidemiological studies have been limited by small sample sizes, and a lack of harmonization of methods used to quantify radiation doses resulting from uranium exposure. Experimental studies have shown that uranium has biological effects, but their implications for human health are not clear. New studies that would combine the strengths of large, well-designed epidemiological datasets with those of state-of-the-art biological methods would help improve the characterization of the biological and health effects of occupational uranium exposure. The aim of the European Commission concerted action CURE (Concerted Uranium Research in Europe) was to develop protocols for such a future collaborative research project, in which dosimetry, epidemiology and biology would be integrated to better characterize the effects of occupational uranium exposure. These protocols were developed from existing European cohorts of workers exposed to uranium together with expertise in epidemiology, biology and dosimetry of CURE partner institutions. The preparatory work of CURE should allow a large scale collaborative project to be launched, in order to better characterize the effects of uranium exposure and more generally of alpha particles and low doses of ionizing radiation.

Niš music festival and avant-garde music: Case studies concert of the Radio Belgrade Electronic Studio and 'John Cage's Evening'

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Cvetković Sonja S.

2017-01-01

Full Text Available In the period of domination of socialist realism and moderate modernism, which meant for the Serbian post-war musical creativity isolation from the European and world trends of musical avant-garde, during the sixties and seventies of the twentieth century music of the Serbian and Yugoslav composers of the younger generation becomes more open to a new sound concepts of serialism, aleatory, electronic media and minimalism. A radical break with tradition and changes in almost all aspects of the new music - aesthetics, notation, sound realization - made difficult to establish a clear criteria for its evaluation and therefore, the general reception of the most actual tendencies. Beside two institutional musical places where the contemporary world and national music was performed and promoted - International Music Biennale Zagreb, founded in 1961 and annual Review of Yugoslav Music in Opatija, founded in 1964 (since 1979 under the name Review of Musical Creativity of Yugoslavia, concert and festival stages in the leading musical centers in former Yugoslavia have shown considerable restraint to the contemporary music. In the case of the reception of electro-acoustic compositions created in the Radio Belgrade Electronic Studio and John Cage's sonatas for prepared piano that were performed at the Niš (October Music Festival during the eighties of the 20th century, the paper discusses about the representation of avant-garde music at this manifestation and openness of the local public towards the contemporary compositional streams. At the concert held in 1981 in the hall of the Niš Symphony Orchestra were presented the latest achievements of the composers Miloš Petrović (Anton with or without Webern, 1981, Paul Pignon (Cartoon, 1980, Janez Matičič (Fusions, 1979, Vladan Radovanović (Audiospacial, 1975-78 and Dragoslav Ortakov (Eleorp, 1976 realized in the Radio Belgrade Electronic Studio founded in 1971. Serbian pianist Nada Kolundžija performed in

DRAWING MUSIC! ANAL Y Z ING AN EXTRACURRICULAR ACTIVITY OF VISUALI Z ING A CONCERT

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Váradi, Judit

2018-01-01

Full Text Available According to the literature and recent studies, a high number of encounters with classical music during childhood and adolescence in the context of positive feelings closely correlates with the formation of classical music competencies. During the investigation of primary students’ attitudes towards classical music, it has been revealed that those who have more opportunities to enter music education will come closer to understanding classical music. At the University of Debrecen Faculty of Music, we have organised and staged various educational youth performances in the last decades. Our goal is to get elementary school children acquainted with live music, classical instruments. A key element of our mission is to form the preferences of children and young people who do not participate in art education, so that they may become interested and sophisticated adults. In our paper we analysis the creations of the drawing competition what connects in theme with the youth concert.

Review and comment on the US Department of Energy Site Characterization Plan Conceptual Design report

International Nuclear Information System (INIS)

1988-10-01

The ''Site Characterization Plan Conceptual Design Report,'' as prepared by the United States Department of Energy and its contractors, depicts the conceptual designs being proposed for the Yucca Mountain, Nevada High-Level Waste Repository. Much of the report is comprised of designs based on large assumptions that lead to inconclusiveness in terms of technical integrity and reasonableness. As a result, the likely success of the designs proposed within the report is highly questionable from a technical and even constructibility standpoint. Grave deficiencies have been found throughout the report ranging from the over-simplification of the geologic and geohydrologic setting to the incorrect determination of the repository horizon's host rock strength. All of these deficiencies found within the report relate directly to the probable outcome of the site characterization of Yucca Mountain and the possible design and construction of a high-level waste repository at the site. It does not appear that a concerted effort has been put forth to develop many of the concepts within the report to a reasonable level of engineering and scientific integrity that would be suitable to meet the needs of and provide the results to the Nation's High-Level Waste Program

Management of split skin graft donor site in the West African sub region: survey of plastic surgeons' practice.

Science.gov (United States)

Olawoye, O A; Ademola, S A; Iyun, A O; Michael, A I; Oluwatosin, O M

2017-06-30

Split skin graft (SSG) is one of the most commonly performed operations on any Plastic Surgery service. Rate of donor site healing is affected by various factors including the type of dressing applied. The aim of this study was to survey the practice of plastic surgeons in the sub region with respect to management of SSG donor site and see how it conforms to international standards. Structured questionnaires on various aspects of the harvest and management of SSG donor sites were administered to plastic surgeons during the 53rd annual conference of the West African College of Surgeons (WACS) at Lome, Togo in March 2013. The data were analyzed using descriptive statistics. There were 47 respondents out of 55 plastic surgeons from four West African countries, which represented 85.4% of registered participants at the plastic surgery section of the conference. All the respondents performed SSG regularly, and the thigh was the most commonly used donor site. Different types of paraffin gauze remained the most commonly used primary donor site dressing. Only 17% of the respondents apply a topical local anaesthetic agent on the donor site. The choice of SSG donor site dressing in the sub region was driven mainly by availability. Concerted efforts must be made to access newer wound care products for optimum management of this commonly performed operation.

Mapping sound intensities by seating position in a university concert band: A risk of hearing loss, temporary threshold shifts, and comparisons with standards of OSHA and NIOSH

Science.gov (United States)

Holland, Nicholas Vedder, III

Exposure to loud sounds is one of the leading causes of hearing loss in the United States. The purpose of the current research was to measure the sound pressure levels generated within a university concert band and determine if those levels exceeded permissible sound limits for exposure according to criteria set by the Occupational Safety and Health Administration (OSHA) and the National Institute of Occupational Safety and Health (NIOSH). Time-weighted averages (TWA) were obtained via a dosimeter during six rehearsals for nine members of the ensemble (plus the conductor), who were seated in frontal proximity to "instruments of power" (trumpets, trombones, and percussion; (Backus, 1977). Subjects received audiometer tests prior to and after each rehearsal to determine any temporary threshold shifts (TTS). Single sample t tests were calculated to compare TWA means and the maximum sound intensity exposures set by OSHA and NIOSH. Correlations were calculated between TWAs and TTSs, as well as TTSs and the number of semesters subjects reported being seated in proximity to instruments of power. The TWA-OSHA mean of 90.2 dBA was not significantly greater than the specified OSHA maximum standard of 90.0 dBA (p > .05). The TWA-NIOSH mean of 93.1 dBA was, however, significantly greater than the NIOSH specified maximum standard of 85.0 dBA (p OSHA, r = .20 for NIOSH); the correlation between TTSs and semesters of proximity to instruments of power was also considered weak (r = .13). TWAs cumulatively exceeded both association's sound exposure limits at 11 specified locations (nine subjects and both ears of the conductor) throughout the concert band's rehearsals. In addition, hearing acuity, as determined by TTSs, was substantially affected negatively by the intensities produced in the concert band. The researcher concluded that conductors, as well as their performers, must be aware of possible damaging sound intensities in rehearsals or performances.

Visiting the cinema, concerts, museums or art exhibitions as determinant of survival: a Swedish fourteen-year cohort follow-up.

Science.gov (United States)

Konlaan, B B; Bygren, L O; Johansson, S E

2000-09-01

The aim of this study was to ascertain the possible influence of attending various kinds of cultural events or visiting cultural institutions as a determinant of survival. A cohort of individuals aged 25-74 years from a random sample were interviewed by trained non-medical interviewers in 1982 and 1983. The interviews covered standard-of-living variables. Our independent variables covered visiting cultural institutions and attendance at cultural events, reading books or periodicals, and music making. The non-response rate was about 25%. The cohort was followed with respect to survival for 14 years up to 31st December 1996. The background covariates that were used for control purposes were age, sex, cash buffer, educational standard, long-term disease, smoking, and physical exercise. Our setting was the Swedish survey of living conditions among the adult Swedish population aged 25-74 years. About 10,609 individuals were interviewed in 1982 and 1983. The outcome measure was survival until 31st December 1996. In all, 916 men and 600 women died during this period. We found a higher mortality risk for those people who rarely visited the cinema, concerts, museums, or art exhibitions compared with those visiting them most often. The significant relative risks ranging between RR 1.14 (95% CI. 1.01-1.31) of attending art exhibitions, and RR 1.42 (CI. 1.25-1.60) of attending museums, when adjusting for the nine other variables. Visits to the cinema and concerts gave significant RR in between. We could not discern any beneficial effect of attending the theatre, church service or sports event as a spectator or any effect of reading or music making. Our conclusion is that attendance at certain kinds of cultural events may have a beneficial effect on longevity.

Operational Circular No.2 (Rev. 2) - Conditions of access to the fenced parts of the CERN site

CERN Multimedia

2014-01-01

Operational Circular No. 2 (Rev. 2) entitled “Conditions of access to the fenced parts of the CERN site” and its “implementation measures”, approved by the Director-General following discussion at the Standing Concertation Committee meeting on 20 May 2014 and entering into force on 1 September 2014, are available on the intranet site of the Human Resources Department (see here).   This circular is applicable to members of the personnel and other persons concerned. It cancels and replaces Operational Circular No. 2 (Rev. 1) entitled “Conditions of access to the fenced parts of the CERN site”, of April 1998. In particular, the revised circular provides for the possibility of mandating a person responsible for the proper implementation of the circular, specifies the rules relating to vehicles allowed on the site and the respective responsibilities of their owners, and relaxes certain administrative formalities in case of loss, theft or di...

High-Resolution Profiling of Drosophila Replication Start Sites Reveals a DNA Shape and Chromatin Signature of Metazoan Origins

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Federico Comoglio

2015-05-01

Full Text Available At every cell cycle, faithful inheritance of metazoan genomes requires the concerted activation of thousands of DNA replication origins. However, the genetic and chromatin features defining metazoan replication start sites remain largely unknown. Here, we delineate the origin repertoire of the Drosophila genome at high resolution. We address the role of origin-proximal G-quadruplexes and suggest that they transiently stall replication forks in vivo. We dissect the chromatin configuration of replication origins and identify a rich spatial organization of chromatin features at initiation sites. DNA shape and chromatin configurations, not strict sequence motifs, mark and predict origins in higher eukaryotes. We further examine the link between transcription and origin firing and reveal that modulation of origin activity across cell types is intimately linked to cell-type-specific transcriptional programs. Our study unravels conserved origin features and provides unique insights into the relationship among DNA topology, chromatin, transcription, and replication initiation across metazoa.

COMMUNICATIONAL THINKING IN THE STATE ORCHESTRA OF MATO GROSSO AND THE FIELD OF CONCERT MUSIC IN CUIABÁ

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Yuji Gushiken

2016-12-01

Full Text Available Na perspectiva da “comunicação como cultura”, este artigo tem como questão central a relação entre pensamento comunicacional e a formação da música de concerto como campo artístico-cultural, num estudo de caso da Orquestra do Estado de Mato Grosso (OEMT. Criada em 2005, a OEMT instituiu um novo momento para a música de concerto em Cuiabá, capital de Mato Grosso, estado do Centro-Oeste com parte de seu território na Amazônia Legal. O funcionamento da OEMT na primeira década de atividade (2005-2015 atualiza-se com o desenvolvimento paralelo de estratégias de comunicação organizacional que redimensionam as relações da orquestra junto a seus diversos públicos. A interface entre distintos campos profissionais evidencia a dimensão comunicacional das práticas artísticas e culturais na contemporaneidade.   PALAVRAS-CHAVE: Comunicação; Música de concerto; Orquestra do Estado de Mato Grosso; Cuiabá.     ABSTRACT In the perspective of “communication as culture”, this article has as its central question the relationship between communicational thinking and the formation of concert music as an artistic-cultural field, in a case study of the State Orchestra of Mato Grosso (OEMT. Created in 2005, OEMT instituted a new moment for concert music in Cuiabá, capital of Mato Grosso, state of the Midwest with part of its territory in the Legal Amazon. The operation of OEMT in the first decade of activity (2005-2015 is updated with the parallel development of organizational communication strategies that reshape the relations of the orchestra with its different audiences. The interface between different professional fields evidences the communicational dimension of the artistic and cultural practices in the contemporaneity.   KEYWORDS: Communication; Concert music; State Orchestra of  Mato Grosso; Cuiabá.     RESUMEN Desde la perspectiva de la “comunicación como cultura”, este artículo tiene como cuestión central la

Quality assessment in in vivo NMR spectroscopy: IV. A multicentre trial of test objects and protocols for performance assessment in clinical NMR spectroscopy

DEFF Research Database (Denmark)

Keevil, S.F.; Barbiroli, B; Collins, D.J.

1995-01-01

implemented on commercially available MR systems at ten sites in Europe. At each site, a number of parameters devised by the Concerted Action were measured using prototype test objects. Some of these parameters related to the quality of localisation and others to the overall performance of the spectrometer...... in the development of the Concerted Action's final recommendations for MRS performance assessment, and demonstrate that such assessment provides valuable information in the comparison of spectroscopy data from different sites and in the development of new localisation sequences, and provides a means of quality...... assurance in MRS...

Profil épidémiologique des hémoglobinopathies: étude transversale descriptive autour du cas index

Science.gov (United States)

Dahmani, Fatima; Benkirane, Souad; Kouzih, Jaafar; Woumki, Aziz; Mamad, Hassan; Masrar, Azlarab

2017-01-01

Les hémoglobinopathies sont des affections constitutionnelles conséquentes à des anomalies des hémoglobines. Elles sont souvent graves dans leurs formes majeures, leur prise en charge est lourde avec un grand impact psycho-social sur les patients et leur famille. Classées parmi les maladies rares, elles sont encore insuffisamment connues des professionnels de santé. Cette méconnaissance est à l'origine d'une errance diagnostique, d'un retard dans leur prise en charge et par conséquent une morbidité et une mortalité élevée chez ces patients. L'Organisation Mondiale de la Santé (OMS) a publié en 2008 des données concernant l'épidémiologie des hémoglobinopathies: plus de 330000 cas naissent chaque année avec une hémoglobinopathie (83% des cas de drépanocytose, 17% des cas de thalassémie). Les troubles de l'hémoglobine sont responsables d'environ 3,4% des décès chez les moins de 5 ans. A l'échelle mondiale, 7% environ des femmes enceintes seraient porteuses d'une forme de la thalassémie et 1% des couples sont à risque. Toutefois, elles sont relativement fréquentes dans certaines régions du globe où les mariages consanguins sont communs. Afin de décrire les caractéristiques épidémiologiques des familles à risque d'hémoglobinopathies (étude autour du cas) dont les cas index sont suivis au service de pédiatrie à l'Hôpital Provincial El Idrisi de Kenitra au Maroc, une étude transversale descriptive a été réalisée durant deux enquêtes la première en mai 2015 et la deuxième en juin de la même année lors des journées de vaccination des cas index contre le pneumocoque. Après avoir recueilli les données épidémiologiques de nos patients, nous avons réalisé une étude biologique comportant: l'hémogramme avec étude morphologique des globules rouges en coloration MGG et numération automatique des réticulocytes; les électrophorèses de l'hémoglobine à pH alcalin (8.8) et secondairement à pH acide (5.4) sur gel d

Human breast cancer: concerted role of diet, prolactin and adrenal C19-delta 5-steroids in tumorigenesis.

Science.gov (United States)

Adams, J B

1992-04-01

The low incidence of breast cancer in Japan disappears within 2 generations in migrant Japanese in the USA. This is of fundamental importance if we are to understand, and perhaps reverse, the high rate seen in Western countries. Diet is the most likely factor involved, and a review of the topic of diet, body mass index, and gain in adult body mass, supports a relationship between these factors and breast-cancer risk in post-menopausal, but not pre-menopausal, women. A direct link between nutritional factors and secretion of the hormones prolactin and dehydroepiandrosterone sulfate is proposed. An estrogen 5-androstene-3 beta, 17 beta-diol is formed peripherally from the latter steroid, and in Western women attains a blood concentration at which it is biologically active. Thus diet/fat provides factors, viz., fatty acids, prolactin and estrogen, which in concerted fashion provide a milieu conducive to mammary tumorigenesis.

Site-specific DNA Inversion by Serine Recombinases

Science.gov (United States)

2015-01-01

Reversible site-specific DNA inversion reactions are widely distributed in bacteria and their viruses. They control a range of biological reactions that most often involve alterations of molecules on the surface of cells or phage. These programmed DNA rearrangements usually occur at a low frequency, thereby preadapting a small subset of the population to a change in environmental conditions, or in the case of phages, an expanded host range. A dedicated recombinase, sometimes with the aid of additional regulatory or DNA architectural proteins, catalyzes the inversion of DNA. RecA or other components of the general recombination-repair machinery are not involved. This chapter discusses site-specific DNA inversion reactions mediated by the serine recombinase family of enzymes and focuses on the extensively studied serine DNA invertases that are stringently controlled by the Fis-bound enhancer regulatory system. The first section summarizes biological features and general properties of inversion reactions by the Fis/enhancer-dependent serine invertases and the recently described serine DNA invertases in Bacteroides. Mechanistic studies of reactions catalyzed by the Hin and Gin invertases are then discussed in more depth, particularly with regards to recent advances in our understanding of the function of the Fis/enhancer regulatory system, the assembly of the active recombination complex (invertasome) containing the Fis/enhancer, and the process of DNA strand exchange by rotation of synapsed subunit pairs within the invertasome. The role of DNA topological forces that function in concert with the Fis/enhancer controlling element in specifying the overwhelming bias for DNA inversion over deletion and intermolecular recombination is emphasized. PMID:25844275

Destructive textures around radioactive minerals; Les textures destructives autour des mineraux radioactifs

Energy Technology Data Exchange (ETDEWEB)

Montel, J.M. [ENSG-G2R, CNRS-Nancy-Universite, 54 - Vandoeuvre-les-Nancy (France); Seydoux-Guillaume, A.M. [LMTG, CNRS-UPS-IRD, Universite de Toulouse, OMP, 31 - Toulouse (France)

2009-07-01

In most of the rocks, natural uranium and thorium are concentrated in some minerals which provide favourable crystallographic sites. These minerals are thus submitted to an intense auto-irradiation which may transform them. Using conventional investigation methods (petrographic or scanning electronic microscopy, electronic micro-probe) and less conventional ones (transmission electronic microscopy), the authors studied the interfaces between radioactive minerals and their host minerals. They comment the possible mechanical and structural aspects of this interaction by irradiation, and the influence of geological events

Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA

Science.gov (United States)

Richter, Sara N.; Menegazzo, Ileana; Fabris, Daniele; Palumbo, Manlio

2004-01-01

Clerocidin (CL) is a topoisomerase II poison, which cleaves DNA irreversibly at guanines (G) and reversibly at cytosines (C). Furthermore, the drug can induce enzyme-independent strand breaks at the G and C level. It has been previously shown that G-damage is induced by alkylation of the guanine N7, followed by spontaneous depurination and nucleic acid cleavage, whereas scission at C is obtained only after treatment with hot alkali, and no information is available to explain the nature of this damage. We present here a systematic study on the reactivity of CL towards C both in the DNA environment and in solution. Selected synthetic derivatives were employed to evaluate the role of each chemical group of the drug. The structure of CL–dC adduct was then characterized by tandem mass spectrometry and NMR: the adduct is a stable condensed ring system resulting from a concerted electrophilic attack of the adjacent carbonyl and epoxide groups of CL towards the exposed NH2 and N3, respectively. This reaction mechanism, shown here for the first time, is characterized by faster kinetic rates than alkylation at G, due to the fact that the rate-determining step, alkylation at the epoxide, is an intramolecular process, provided a Schiff base linking CL and C can rapidly form, whereas the corresponding reaction of G N7 is intermolecular. These results provide helpful hints to explain the reversible/irreversible nature of topoisomerase II mediated DNA damage produced by CL at C/G steps. PMID:15494453

Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells

DEFF Research Database (Denmark)

Hattori, Naoko; Niwa, Tohru; Kimura, Kana

2013-01-01

. Bivalent modification was clearly visualized by iChmo in wild-type embryonic stem cells (ESCs) known to have it, whereas rarely in Suz12 knockout ESCs and mouse embryonic fibroblasts known to have little of it. iChmo was applied to analysis of epigenetic and phenotypic changes of heterogeneous cell......Combinations of histone modifications have significant biological roles, such as maintenance of pluripotency and cancer development, but cannot be analyzed at the single cell level. Here, we visualized a combination of histone modifications by applying the in situ proximity ligation assay, which...... population, namely, ESCs at an early stage of differentiation, and this revealed that the bivalent modification disappeared in a highly concerted manner, whereas phenotypic differentiation proceeded with large variations among cells. Also, using this method, we were able to visualize a combination...

Protein crystal growth on board Shenzhou 3: a concerted effort improves crystal diffraction quality and facilitates structure determination

International Nuclear Information System (INIS)

Han, Y.; Cang, H.-X.; Zhou, J.-X.; Wang, Y.-P.; Bi, R.-C.; Colelesage, J.; Delbaere, L.T.J.; Nahoum, V.; Shi, R.; Zhou, M.; Zhu, D.-W.; Lin, S.-X.

2004-01-01

The crystallization of 16 proteins was carried out using 60 wells on board Shenzhou 3 in 2002. Although the mission was only 7 days, careful and concerted planning at all stages made it possible to obtain crystals of improved quality compared to their ground controls for some of the proteins. Significantly improved resolutions were obtained from diffracted crystals of 4 proteins. A complete data set from a space crystal of the PEP carboxykinase yielded significantly higher resolution (1.46 A vs. 1.87 A), I/sigma (22.4 vs. 15.5), and a lower average temperature factor (29.2 A 2 vs. 42.9 A 2 ) than the best ground-based control crystal. The 3-D structure of the enzyme is well improved with significant ligand density. It has been postulated that the reduced convection and absence of macromolecule sedimentation under microgravity have advantages/benefits for protein crystal growth. Improvements in experimental design for protein crystal growth in microgravity are ongoing

Control of concerted two bond versus single bond dissociation in CH3Co(CO)4 via an intermediate state using pump-dump laser pulses

Science.gov (United States)

Ambrosek, David; González, Leticia

2007-10-01

Wavepacket propagations on ab initio multiconfigurational two-dimensional potential energy surfaces for CH3Co(CO)4 indicate that after irradiation to the lowest first and second electronic excited states, concerted dissociation of CH3 and the axial CO ligand takes place. We employ a pump-dump sequence of pulses with appropriate frequencies and time delays to achieve the selective breakage of a single bond by controlling the dissociation angle. The pump and dump pulse sequence exploits the unbound surface where dissociation occurs in a counterintuitive fashion; stretching of one bond in an intermediate state enhances the single dissociation of the other bond.

Control of concerted two bond versus single bond dissociation in CH(3)Co(CO)(4) via an intermediate state using pump-dump laser pulses.

Science.gov (United States)

Ambrosek, David; González, Leticia

2007-10-07

Wavepacket propagations on ab initio multiconfigurational two-dimensional potential energy surfaces for CH(3)Co(CO)(4) indicate that after irradiation to the lowest first and second electronic excited states, concerted dissociation of CH(3) and the axial CO ligand takes place. We employ a pump-dump sequence of pulses with appropriate frequencies and time delays to achieve the selective breakage of a single bond by controlling the dissociation angle. The pump and dump pulse sequence exploits the unbound surface where dissociation occurs in a counterintuitive fashion; stretching of one bond in an intermediate state enhances the single dissociation of the other bond.

Use of integrated geologic and geophysical information for characterizing the structure of fracture systems at the US/BK Site, Grimsel Laboratory, Switzerland

International Nuclear Information System (INIS)

Martel, S.J.; Peterson, J.E. Jr.

1990-05-01

Fracture systems form the primary fluid flow paths in a number of rock types, including some of those being considered for high level nuclear waste repositories. In some cases, flow along fractures must be modeled explicitly as part of a site characterization effort. Fractures commonly are concentrated in fracture zones, and even where fractures are seemingly ubiquitous, the hydrology of a site can be dominated by a few discrete fracture zones. We have implemented a site characterization methodology that combines information gained from geophysical and geologic investigations. The general philosophy is to identify and locate the major fracture zones, and then to characterize their systematics. Characterizing the systematics means establishing the essential and recurring patterns in which fractures are organized within the zones. We make a concerted effort to use information on the systematics of the fracture systems to link the site-specific geologic, borehole and geophysical information. This report illustrates how geologic and geophysical information on geologic heterogeneities can be integrated to guide the development of hydrologic models. The report focuses on fractures, a particularly common type of geologic heterogeneity. However, many aspects of the methodology we present can be applied to other geologic heterogeneities as well. 57 refs., 40 figs., 1 tab

Intercorrência audiológica em músicas após um show de rock Hearing incidents in musicians after a rock concert

Directory of Open Access Journals (Sweden)

Marcela Pfeiffer

2007-09-01

Full Text Available OBJETIVO: verificar mudança temporária do limiar de audição de músicos, após exposição a níveis de pressão sonora elevados de um show de rock. MÉTODOS: foi utilizada uma amostra com seis músicos componentes da banda. Foram feitos: anamnese ocupacional, determinação dos níveis mínimos de audição e reflexos acústicos, antes e após o show de rock. A mensuração do ruído da sala do exame e do palco foi realizada por meio de um dosímetro. Os resultados foram comparados e analisados estatisticamente, utilizando-se o teste t Student, com critério para determinação de significância de p maior do que 0,05. RESULTADOS: para a dosimetria, foi encontrada a exposição ao ruído do show com valor de LAVG igual a 98,5 dB. Dentre os aspectos comportamentais relacionados ao ruído, o zumbido foi a queixa mais presente entre os integrantes. Na audiometria tonal, as maiores diferenças pré e pós-exposição, foram encontradas nas freqüências altas, sendo a orelha direita a que apresentou maiores mudanças temporárias de limiar. Os resultados foram significantes nas freqüências de 2000, 3000, 4000 e 6000 Hz, na orelha direita (p=2,7; p=2,59; p=3,7 e p=2,86 e, na freqüência de 4000 Hz, na orelha esquerda (p=2,87. Na medida do reflexo acústico após o show, a orelha direita obteve o maior índice de ausência de reflexo, com o índice de 40%; entretanto, foram encontradas diferenças estatisticamente significantes, na presença de reflexo acústico na comparação pré e pós-exposição, apenas na orelha esquerda (p=3,64. CONCLUSÃO: músicos expostos a níveis de pressão sonora intensos apresentaram alteração temporária do limiar e alteração do reflexo acústico.PURPOSE: verifying the temporary threshold shift in musicians after a high sound pressure level music exposure in a rock concert. METHODS: the sample has been made up of six band's musicians, who underwent an occupational anamnesis, pure tone audiometry and

Legami curati – Legami curanti "Cliniche della Concertazione" e violenze di quartiere / Liens soignés, liens soignant. « Cliniques de Concertation » et violences de quartiers

Directory of Open Access Journals (Sweden)

Jean-Marie Lemaire

2007-12-01

Full Text Available Mahdi is twenty-six years old, he is tall and athletic. He is blind, because he was attacked. This kind of situation puts at work a complex network of professionals of help, care, education and control, beyond everything they can expect. The methodology of the « Clinic of Concertation », as a « Laboratory of applied communicational ethics », recognises that Mahdi and the members of his family are directly part of this network. If the professionals do not resist to this collective construction, they will see laying out different relational systems in balance from which they can exploit the resources in the process of reconstructive links. More than a narrative device, the "Clinic of Concertation" is a creative therapeutic device governed by random rules beyond an absolute mastery. It is, in a collective discussion that does not exclude any member of the collective, but on the contrary, that promotes every extensive step, about differentiating without dissociating, with all interested persons, what will belong to the private sphere and what will belong to the public sphere, while recognizing the legitimacy of the compensatory dynamics of revenge and the protective dynamics of future generations, by identifying their joints, their compatibilities and their incompatibilities, by developing preferentially those reconstructive and preventive.Mahdi a vingt-six ans, il est grand et de stature athlétique. Il est aveugle. Il a été victime d’une agression qui lui a ôté la vue. Une situation comme celle de Mahdi met au travail un réseau complexe associant des professionnels de l’aide, du soin, de l’éducation et du contrôle, au-delà de ce que ces mêmes professionnels peuvent imaginer. La Méthodologie de la « Clinique de Concertation », en tant que « Laboratoire d’éthique communicationelle appliquée», reconnaît que Mahdi et les membres de sa famille font d’emblée partie des architectes de ce réseau. Si les professionnels ne r

Population around the French nuclear power plant sites: a key-parameter for crisis management and safety economics; La population autour des sites nucleaires francais: un parametre determinant pour la gestion de crise et l'analyse economique des accidents nucleaires

Energy Technology Data Exchange (ETDEWEB)

PASCAL, A. [IRSN, Laboratoire d' economie de la surete, DSDP/SPIIC/LAERN, BP 17, 92262 Fontenay-aux-Roses (France)

2012-01-15

This paper undertakes an analysis of population around the French nuclear power plant sites, tackles the problem of evacuation planning and provides a glimpse into ongoing research at the Laboratory of Nuclear Safety Economics of the IRSN, about the cost assessment of a nuclear accident and long-term land contamination. (author)

Conditioning Methodologies for DanceSport: Lessons from Gymnastics, Figure Skating, and Concert Dance Research.

Science.gov (United States)

Outevsky, David; Martin, Blake Cw

2015-12-01

Dancesport, the competitive branch of ballroom dancing, places high physiological and psychological demands on its practitioners, but pedagogical resources in these areas for this dance form are limited. Dancesport competitors could benefit from strategies used in other aesthetic sports. In this review, we identify conditioning methodologies from gymnastics, figure skating, and contemporary, modern, and ballet dance forms that could have relevance and suitability for dancesport training, and propose several strategies for inclusion in the current dancesport curriculum. We reviewed articles derived from Google Scholar, PubMed, ScienceDirect, Taylor & Francis Online, and Web of Science search engines and databases, with publication dates from 1979 to 2013. The keywords included MeSH terms: dancing, gymnastics, physiology, energy metabolism, physical endurance, and range of motion. Out of 47 papers examined, 41 papers met the inclusion criteria (validity of scientific methods, topic relevance, transferability to dancesport, publication date). Quality and validity of the data were assessed by examining the methodologies in each study and comparing studies on similar populations as well as across time using the PRISMA 2009 checklist and flowchart. The relevant research suggests that macro-cycle periodization planning, aerobic and anaerobic conditioning, range of motion and muscular endurance training, and performance psychology methods have potential for adaptation for dancesport training. Dancesport coaches may help their students fulfill their ambitions as competitive athletes and dance artists by adapting the relevant performance enhancement strategies from gymnastics, figure skating, and concert dance forms presented in this paper.

Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.

Science.gov (United States)

Lorente, Elena; Barriga, Alejandro; Johnstone, Carolina; Mir, Carmen; Jiménez, Mercedes; López, Daniel

2013-01-01

In the classical human leukocyte antigen (HLA) class I antigen processing and presentation pathway, the antigenic peptides are generated from viral proteins by multiple proteolytic cleavages of the proteasome (and in some cases other cytosolic proteases) and transported to the endoplasmic reticulum (ER) lumen where they are exposed to aminopeptidase activity. In human cells, two different ER-resident enzymes, ERAP1 and ERAP2, can trim the N-terminally extended residues of peptide precursors. In this study, the possible cooperative effect of generating five naturally processed HLA-B27 ligands by both proteases was analyzed. We identified differences in the products obtained with increased detection of natural HLA-B27 ligands by comparing double versus single enzyme digestions by mass spectrometry analysis. These in vitro data suggest that each enzyme can use the degradation products of the other as a substrate for new N-terminal trimming, indicating concerted aminoproteolytic activity of ERAP 1 and ERAP2.

Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.

Directory of Open Access Journals (Sweden)

Elena Lorente

Full Text Available In the classical human leukocyte antigen (HLA class I antigen processing and presentation pathway, the antigenic peptides are generated from viral proteins by multiple proteolytic cleavages of the proteasome (and in some cases other cytosolic proteases and transported to the endoplasmic reticulum (ER lumen where they are exposed to aminopeptidase activity. In human cells, two different ER-resident enzymes, ERAP1 and ERAP2, can trim the N-terminally extended residues of peptide precursors. In this study, the possible cooperative effect of generating five naturally processed HLA-B27 ligands by both proteases was analyzed. We identified differences in the products obtained with increased detection of natural HLA-B27 ligands by comparing double versus single enzyme digestions by mass spectrometry analysis. These in vitro data suggest that each enzyme can use the degradation products of the other as a substrate for new N-terminal trimming, indicating concerted aminoproteolytic activity of ERAP 1 and ERAP2.

Cast iron transport, storage and disposal containers for use in UK nuclear licensed sites - 59412

International Nuclear Information System (INIS)

Viermann, Joerg; Messer, Matthias P.

2012-01-01

Document available in abstract form only. Full text of publication follows: Ductile Cast Iron Containers of the types GCVI (UK trademark -GNS YELLOW BOX R ) and MOSAIK R have been in use in Germany for transport, storage and disposal of intermediate level radioactive waste (ILW) for more than two decades. In 2009 a number of containers of these types were delivered to various Magnox sites as so called pathfinders to test their suitability for Magnox waste streams. The results were encouraging. Therefore the Letter of Compliance (LoC) procedure was started to prove the suitability of packages using these types of containers for the future UK Geological Disposal Facility (GDF) and a conceptual Letter of Compliance (cLoC) was obtained from RWMD in 2010. Waste stream specific applications for Interim Stage Letters of Compliance (ILoC) for a number of waste streams from different Magnox sites and from the UK's only pressurised water reactor, Sizewell B are currently being prepared and discussed with RWMD. In order to achieve a package suitable for interim storage and disposal the contents of a Ductile Cast Iron Container only has to be dried. Mobile drying facilities are readily available. Containers and drying facilities form a concerted system

Concerted changes in N and C primary metabolism in alfalfa (Medicago sativa) under water restriction.

Science.gov (United States)

Aranjuelo, Iker; Tcherkez, Guillaume; Molero, Gemma; Gilard, Françoise; Avice, Jean-Christophe; Nogués, Salvador

2013-02-01

Although the mechanisms of nodule N(2) fixation in legumes are now well documented, some uncertainty remains on the metabolic consequences of water deficit. In most cases, little consideration is given to other organs and, therefore, the coordinated changes in metabolism in leaves, roots, and nodules are not well known. Here, the effect of water restriction on exclusively N(2)-fixing alfalfa (Medicago sativa L.) plants was investigated, and proteomic, metabolomic, and physiological analyses were carried out. It is shown that the inhibition of nitrogenase activity caused by water restriction was accompanied by concerted alterations in metabolic pathways in nodules, leaves, and roots. The data suggest that nodule metabolism and metabolic exchange between plant organs nearly reached homeostasis in asparagine synthesis and partitioning, as well as the N demand from leaves. Typically, there was (i) a stimulation of the anaplerotic pathway to sustain the provision of C skeletons for amino acid (e.g. glutamate and proline) synthesis; (ii) re-allocation of glycolytic products to alanine and serine/glycine; and (iii) subtle changes in redox metabolites suggesting the implication of a slight oxidative stress. Furthermore, water restriction caused little change in both photosynthetic efficiency and respiratory cost of N(2) fixation by nodules. In other words, the results suggest that under water stress, nodule metabolism follows a compromise between physiological imperatives (N demand, oxidative stress) and the lower input to sustain catabolism.

Folding and membrane insertion of the pore-forming peptide gramicidin occur as a concerted process.

Science.gov (United States)

Hicks, Matthew R; Damianoglou, Angeliki; Rodger, Alison; Dafforn, Timothy R

2008-11-07

Many antibiotic peptides function by binding and inserting into membranes. Understanding this process provides an insight into the fundamentals of both membrane protein folding and antibiotic peptide function. For the first time, in this work, flow-aligned linear dichroism (LD) is used to study the folding of the antibiotic peptide gramicidin. LD provides insight into the combined processes of peptide folding and insertion and has the advantage over other similar techniques of being insensitive to off-membrane aggregation events. By combining LD data with conventional measurements of protein fluorescence and circular dichroism, the mechanism of gramicidin insertion is elucidated. The mechanism consists of five separately assignable steps that include formation of a water-insoluble gramicidin aggregate, dissociation from the aggregate, partitioning of peptide to the membrane surface, oligomerisation on the surface and concerted insertion and folding of the peptide to the double-helical form of gramicidin. Measurement of the rates of each step shows that although changes in the fluorescence signal cease 10 s after the initiation of the process, the insertion of the peptide into the membrane is actually not complete for a further 60 min. This last membrane insertion phase is only apparent by measurement of LD and circular dichroism signal changes. In summary, this study demonstrates the importance of multi-technique approaches, including LD, in studies of membrane protein folding.

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Staff Association

2013-01-01

Concert Scoop music tour sur le parc Walibi ! Vendredi 12 Juillet Vous trouverez la présentation de l’événement et les vidéos des artistes attendus avec leurs titres faisant vibrer les radios en ce moment sur le site internet http://www.walibi.com/rhone-alpes/fr-fr/evenements/scoop-music-tour. Le concert est gratuit et débute à la fermeture du parc avec une première partie surprise. Profitez donc d’une belle journée sur le parc et finissez en beauté avec le concert de l’été !

Guide de l’environnement et de la qualité de l’habitat - édition 2004-2005, Paris, La documentation française, Collection  « droits et démarches », 2004, 160 p.

Directory of Open Access Journals (Sweden)

Amélie Morel

2005-03-01

Full Text Available Cet ouvrage est conçu sous la forme d’un guide pratique proposant, par thématiques retenues autour de l’environnement et de la qualité de l’habitat, une information juridique et administrative, des questions/réponses, ainsi que des adresses utiles et des sites Internet à parcourir. Le Guide de l’environnement et de la qualité de l’habitat s’inscrit dans la collection « droits et démarches » de la documentation française. Il se découpe en deux parties. La première présente la protection de l’e...

Jean-Pierre Abbet & Daniel Stoecklin, « We were talking… » Les Beatles en héritage

OpenAIRE

Nikoghosyan, Nuné

2012-01-01

Voici un ouvrage autour des Beatles qui n’est pas une biographie, ni une étude sociologique, mais une collection d’essais par deux sociologues. Dans « We were talking » Les Beatles en héritage, Jean-Pierre Abbet et Daniel Stoecklin prennent un style discursif libre et, ne visant pas une neutralité scientifique, proposent leurs points de vue personnels sur des thèmes divers autour des Beatles. Les thèmes varient de l’œuvre des Beatles à la « Beatlemania » comme phénomène social, en passant par...

Les déchets militaires : De la conception aux impacts territoriaux

OpenAIRE

Charriere, Elodie; Baudoui, Remi

2017-01-01

Classiquement, la notion de déchet est articulée autour de deux concepts distincts : les déchets ménagers et les déchets industriels. Etant donné le polymorphisme de cette notion et les nombreuses représentations lui incombant, le terme de déchet s’est construit autour de diverses catégories établies dans une triple logique : (i) en fonction de leurs sources de production – déchets industriels, déchets agricoles, déchets hospitaliers, déchets ménagers ; (ii) en fonction de leur consistance – ...

Méditations autour de Socrate

OpenAIRE

Bergeron, Jean-François

2017-01-01

Socrate, aujourd’hui. Quelle pertinence ? Quelle utilité ? Que nous enseignerait-il ? De quoi nous libérerait-il ? Où nous mènerait-il ? Répondre à ces questions, indubitablement, c’est refaire le procès de Socrate, donner notre jugement sur ce dernier. Remarquons que, jour après jour, notre monde serait très près de condamner, comme les Athéniens de l’époque, le philosophe. Alors que nous nous imaginerions une distance infinie entre les contempteurs de Socrate et nous, notre parenté en est p...

Unfolding Utzon

DEFF Research Database (Denmark)

Kirkegaard, Poul Henning

2013-01-01

For many, the architecture by j0rn Utzon is synonymous with the design of the Sydney Opera House (1973) that was made a UNESCO World Heritage Site in 2007, being one of the 20th century's most distinctive buildings and one of the most famous concert halls in the world.......For many, the architecture by j0rn Utzon is synonymous with the design of the Sydney Opera House (1973) that was made a UNESCO World Heritage Site in 2007, being one of the 20th century's most distinctive buildings and one of the most famous concert halls in the world....

Identifying Functional Neighborhoods within the Cell Nucleus: Proximity Analysis of Early S-Phase Replicating Chromatin Domains to Sites of Transcription, RNA Polymerase II, HP1γ, Matrin 3 and SAF-A

Science.gov (United States)

Malyavantham, Kishore S; Bhattacharya, Sambit; Barbeitos, Marcos; Mukherjee, Lopamudra; Xu, Jinhui; Fackelmayer, Frank O; Berezney, Ronald

2009-01-01

Higher order chromatin organization in concert with epigenetic regulation is a key process that determines gene expression at the global level. The organization of dynamic chromatin domains and their associated protein factors is intertwined with nuclear function to create higher levels of functional zones within the cell nucleus. As a step towards elucidating the organization and dynamics of these functional zones, we have investigated the spatial proximities among a constellation of functionally related sites that are found within euchromatic regions of the cell nucleus including: HP1γ, nascent transcript sites (TS), active DNA replicating sites in early S phase (PCNA) and RNA polymerase II sites. We report close associations among these different sites with proximity values specific for each combination. Analysis of matrin 3 and SAF-A sites demonstrates that these nuclear matrix proteins are highly proximal with the functionally related sites as well as to each other and display closely aligned and overlapping regions following application of the minimal spanning tree (MST) algorithm to visualize higher order network-like patterns. Our findings suggest that multiple factors within the nuclear microenvironment collectively form higher order combinatorial arrays of function. We propose a model for the organization of these functional neighborhoods which takes into account the proximity values of the individual sites and their spatial organization within the nuclear architecture. PMID:18618731

Site-specific sediment clean-up objectives developed by the sediment quality triad

International Nuclear Information System (INIS)

Redman, S.; Janisch, T.

1995-01-01

Sediment chemistry, sediment toxicity, and benthic macroinvertebrate community data were collected and evaluated in concert (1) to characterize adverse effects of hydrocarbon and metal contaminants in the sediments of a small inlet of Superior Bay, Lake Superior and a tributary creek and (2) to derive numeric objectives for the clean up of this system. Sediments from reference locations and eight study sites were analyzed for a range of contaminants, including hydrocarbons (measured both as diesel range organics (DRO) and oil and grease), lead, chromium, and ammonia. A range of sediment toxicity was observed across the eight study sites using a variety of tests and endpoints: Hyalella azteca (10 day survival and growth), Chironomus tentans (10 day survival and growth), Ceriodaphnia dubia (48 hour survival), and Daphnia magna (48 hour survival and 10 day survival and reproduction). A range of alterations of the benthic macroinvertebrate community compared with communities from reference locations were observed. Benthic community alterations were summarized quantitatively by taxa richness and Shannon-Weiner mean diversity. Lowest effect levels determined through this study included 150 microg/g dry sediment for DRO (as measured in this study) and 40 microg/g dry sediment for lead. Effects thresholds determined through this study included 1,500 microg/g dry sediment for DRO and 90 microg/g dry sediment for lead. These levels and concentrations measured in relevant reference locations are being used to define objectives for sediment clean up in the inlet and creek

De l’approche savante au projet de développement local. Une étude de cas : les fours à chaux de Lormandière (Ille-et-Vilaine

Directory of Open Access Journals (Sweden)

Jérôme Cucarull

2007-03-01

Full Text Available Le site des fours à chaux de Lormandière a été acquis comme espace naturel sensible par le département d'Ille-et-Vilaine en 1988. L'étude du processus d'émergence d'un projet de valorisation de cette usine est l'occasion de décrypter de manière concrète le jeu des acteurs institutionnels et associatifs qui s'y côtoient. Tout d'abord, faute d'intention précise, le site industriel ne fait l'objet d'aucune valorisation. La création d'une association locale en 1996 permet l’esquisse d’un projet autour de l'énergie. L'intervention d'un cabinet d'étude, qui propose une démarche d'interprétation et de valorisation culturelle, ne convainc pas le Conseil général qui s'en tient à une proposition minimale autour d'un sentier d'interprétation. Parallèlement, le passage d'un projet de site à un projet territorial incluant la métropole rennaise amène une autre ambition pour le lieu, qui pourrait devenir un levier pour le développement d'une valorisation culturelle centrée sur le patrimoine industriel.The site that comprises the Lormandière lime kilns was acquired by the Ille-et-Vilaine departmental council in 1988 as a nature reserve. This article describes how a project for the interpretation of the lime kilns emerged and offers an analysis of the various parts played by different local stakeholders in associations and official institutions. To begin with, there was no specific project for the interpretation of the industrial site, but in 1996 an association of local enthusiasts was created, leading to a project based on the theme of energy. A professional agency for cultural projects subsequently proposed a global programme for the interpretation and promotion of the site, but this proposal did not convince the departmental council, which settled for a more minimalist project comprising a pedestrian itinerary with panels of historic interpretation. At the same time, the project evolved from one involving just the site to a

Site Response and Basin Waves in the Sacramento–San Joaquin Delta, California

Science.gov (United States)

Fletcher, Jon Peter B.; Boatwright, John

2013-01-01

The Sacramento–San Joaquin Delta is an inland delta at the western extent of the Central Valley. Levees were built around swampy islands starting after the Civil War to reclaim these lands for farming. Various studies show that these levees could fail in concert from shaking from a major local or regional earthquake resulting in salty water from the San Francisco Bay contaminating the water in the Delta. We installed seismographs around the Delta and on levees to assess the contribution of site response to the seismic hazard of the levees. Cone penetrometer testing shows that the upper 10 s of meters of soil in the Delta have shear‐wave velocities of about 200  m/s, which would give a strong site response. Seismographs were sited following two strategies: pairs of stations to compare the response of the levees to nearby sites, and a more regional deployment in the Delta. Site response was determined in two different ways: a traditional spectral ratio (TSR) approach of S waves using station BDM of the Berkeley Digital Seismic Net as a reference site, and using SH/SV ratios of noise (or Nakamura’s method). Both estimates usually agree in spectral character for stations whose response is dominated by a resonant peak, but the most obvious peaks in the SH/SV ratios usually are about two‐thirds as large as the main peaks in the TSRs. Levee sites typically have large narrow resonances in the site response function compared to sites in the farmland of the Delta. These resonances, at a frequency of about 1–3 Hz, have amplitudes of about 15 with TSR and 10–12 with Nakamura’s method. Sites on farmland in the Delta also have amplifications, but these are typically broader and not as resonant in appearance. Late (slow) Rayleigh waves were recorded at stations in the Delta, have a dominant period of about one second, and are highly monochromatic. Results from a three‐station array at the Holland Marina suggest that they have a phase velocity of about

Cancer mortality and incidence survey around the Aube's low- and medium-activity radioactive waste storage site; Etude de mortalite et d'incidence des cancers autour du site de stockage de dechets radioactifs de faible et de moyenne activite de l'Aube

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-07-01

This report presents the main results of a survey performed in 2010 to describe the health status of the population around the Aube's low- and medium-activity radioactive waste storage site. The aim of this survey was to determine whether the frequencies of death and hospitalization on account of cancer are different for this population (15 km around the site) with respect to two reference populations (the population of the Champagne-Ardennes region and the French metropolitan population). Results of mortality, hospitalization, and lung cancer are presented under the form of maps and tables giving global data or data for males, females, adults, or children

Nonadiabatic two-electron transfer mediated by an irregular bridge

International Nuclear Information System (INIS)

Petrov, E.G.; Shevchenko, Ye.V.; May, V.

2004-01-01

Nonadiabatic two-electron transfer (TET) mediated by a linear molecular bridge is studied theoretically. Special attention is put on the case of a irregular distribution of bridge site energies as well as on the inter-site Coulomb interaction. Based on the unified description of electron transfer reactions [J. Chem. Phys. 115 (2001) 7107] a closed set of kinetic equations describing the TET process is derived. A reduction of this set to a single exponential donor-acceptor (D-A) TET is performed together with a derivation of an overall D-A TET rate. The latter contains a contribution of the stepwise as well as of the concerted route of D-A TET. The stepwise contribution is determined by two single-electron steps each of them associated with a sequential and a superexchange pathway. A two-electron unistep superexchange transition between the D and A forms the concerted contribution to the overall rate. Both contributions are analyzed in their dependency on the bridge length. The irregular distribution of the bridge site energies as well as the influence of the Coulomb interaction facilitates the D-A TET via a modification of the stepwise and the concerted part of the overall rate. At low temperatures and for short bridges with a single or two units the concerted contribution exceeds the stepwise contribution. If the bridge contains more than two units, the stepwise contribution dominates the overall rate

Paul Wittgenstein's right arm and his phantom: the saga of a famous concert pianist and his amputation.

Science.gov (United States)

Boller, François; Bogousslavsky, Julien

2015-01-01

Reports of postamputation pain and problems linked to phantom limbs have increased in recent years, particularly in relation to war-related amputations. These problems are still poorly understood and are considered rather mysterious, and they are difficult to treat. In addition, they may shed light on brain physiology and neuropsychology. Functional neuroimaging techniques now enable us to better understand their pathophysiology and to consider new rehabilitation techniques. Several artists have suffered from postamputation complications and this has influenced not only their personal life but also their artistic work. Paul Wittgenstein (1887-1961), a pianist whose right arm was amputated during the First World War, became a famous left-handed concert performer. His case provides insight into Post-World War I musical and political history. More specifically, the impact on the artistic life of this pianist illustrates various postamputation complications, such as phantom limb, stump pain, and especially moving phantom. The phantom movements of his right hand helped him develop the dexterity of his left hand. Wittgenstein played piano works that were written especially for him (the most famous being Ravel's Concerto for the Left Hand) and composed some of his own. Additionally, several famous composers had previously written for the left hand. © 2015 Elsevier B.V. All rights reserved.

Evidence for concerted ring opening and C-Br bond breaking in UV-excited bromocyclopropane.

Science.gov (United States)

Pandit, Shubhrangshu; Preston, Thomas J; King, Simon J; Vallance, Claire; Orr-Ewing, Andrew J

2016-06-28

Photodissociation of gaseous bromocyclopropane via its A-band continuum has been studied at excitation wavelengths ranging from 230 nm to 267 nm. Velocity-map images of ground-state bromine atoms (Br), spin-orbit excited bromine atoms (Br(∗)), and C3H5 hydrocarbon radicals reveal the kinetic energies of these various photofragments. Both Br and Br(∗) atoms are predominantly generated via repulsive excited electronic states in a prompt photodissociation process in which the hydrocarbon co-fragment is a cyclopropyl radical. However, the images obtained at the mass of the hydrocarbon radical fragment identify a channel with total kinetic energy greater than that deduced from the Br and Br(∗) images, and with a kinetic energy distribution that exceeds the energetic limit for Br + cyclopropyl radical products. The velocity-map images of these C3H5 fragments have lower angular anisotropies than measured for Br and Br(∗), indicating molecular restructuring during dissociation. The high kinetic energy C3H5 signals are assigned to allyl radicals generated by a minor photochemical pathway which involves concerted C-Br bond dissociation and cyclopropyl ring-opening following single ultraviolet (UV)-photon absorption. Slow photofragments also contribute to the velocity map images obtained at the C3H5 radical mass, but the corresponding slow Br atoms are not observed. These features in the images are attributed to C3H5 (+) from the photodissociation of the C3H5Br(+) molecular cation following two-photon ionization of the parent compound. This assignment is confirmed by 118-nm vacuum ultraviolet ionization studies that prepare the molecular cation in its ground electronic state prior to UV photodissociation.

The joint industry development of a recommended practice for the site specific assessment of mobile jackup units

International Nuclear Information System (INIS)

Jones, D.E.; Bennett, W.T.; Hoyle, M.J.R.

1993-01-01

The mobile self-elevating (drilling) unit, or jack-up, has been central to the exploration and development of offshore oil and gas reserves. In recent years there has been an increased desire to benefit from the potential economics of using these units in longer term production roles either in association with a fixed platform or as a stand-alone facility. However, until recently there had been no concerted effort to develop a consistent and commonly accepted standard for general industry use in site specific assessment of jack-ups. This paper describes the background and work carried out to develop such a standard. The project is nearing completion and has resulted in the publication of a Guideline document. A Recommended Practice and associated Commentary are (at the time of writing) in the final stage of drafting for release to the project sponsors for trial and comment prior to issuing the first Edition early in 1994

Référencement, e-marketing et visibilité web 30 pratiques pour décideurs et webmasters

CERN Document Server

Colantonio, Fred

2013-01-01

Le plus beau site web du monde est inutile s'il est introuvable !Les internautes sont pressés et exigeants; la concurrence nombreuse et organisée. Comment devenir meilleur et plus visible en exploitant des techniques simples ?A travers 30 pratiques, l'auteur répond à 2 préoccupations :- Comment vous trouver quand on vous cherche ?- Comment être visible là où on ne vousattend pas ?Construit principalement autour du référencement naturel et de la présence dans les moteurs de recherche, ce livre vous offre également un aperçu des techniques payantes d'e-marketing. En conclusion, l'exploitation p

Monitoring around the secret nuclear facilities of naval ports; Surveillance autour des INBS des ports militaires

Energy Technology Data Exchange (ETDEWEB)

Jaskierowicz, D. [Marine Nationale, pharmacien en chef, conseiller scientifique et technique, etat-major de la marine, 83 - Toulon (France); Quere, St. [Marine Nationale, capitaine de corvette, adjoint charge de la prise en compte des installations nucleaires sur l' environnement et le personnel, 83 - Toulon (France)

2010-06-15

Based within large industrial cities (Brest, Toulon, Cherbourg) or more rural areas like Crozon (Ile Longue), French navy exploits nuclear facilities where are built, maintained and decommissioned nuclear power submarines and aircraft-carrier. The safety and the security of these installations as well as the non-impact on people and environment are continuously monitored. The DSND, a governmental regulatory body dedicated to the Defense, applies the same regulations enforced by the ASN for civilian nuclear activities. Concerning environmental monitoring, the navy answers to the DSND or the ASN, depending on the type of survey. In every nuclear site, an automatic nuclear monitoring sensor system (2SNM) runs 24/7, with the supervision of specialized personnel in radioprotection. Each year, more than 7000 samples are collected in the ecosystem and thousands of measurements are carried out in four laboratories (LASEM in Cherbourg, Brest and Toulon) - SPRS ILO) of the navy. These results are sent to the DSND and have been integrated since February 2010 to the brand-new public web site of the national monitoring network of radioactivity in the environment (RMN). (author)

Evidence for concerted ring opening and C–Br bond breaking in UV-excited bromocyclopropane

Energy Technology Data Exchange (ETDEWEB)

Pandit, Shubhrangshu; Preston, Thomas J.; Orr-Ewing, Andrew J., E-mail: a.orr-ewing@bristol.ac.uk [School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS (United Kingdom); King, Simon J.; Vallance, Claire [Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA (United Kingdom)

2016-06-28

Photodissociation of gaseous bromocyclopropane via its A-band continuum has been studied at excitation wavelengths ranging from 230 nm to 267 nm. Velocity-map images of ground-state bromine atoms (Br), spin-orbit excited bromine atoms (Br{sup ∗}), and C{sub 3}H{sub 5} hydrocarbon radicals reveal the kinetic energies of these various photofragments. Both Br and Br{sup ∗} atoms are predominantly generated via repulsive excited electronic states in a prompt photodissociation process in which the hydrocarbon co-fragment is a cyclopropyl radical. However, the images obtained at the mass of the hydrocarbon radical fragment identify a channel with total kinetic energy greater than that deduced from the Br and Br{sup ∗} images, and with a kinetic energy distribution that exceeds the energetic limit for Br + cyclopropyl radical products. The velocity-map images of these C{sub 3}H{sub 5} fragments have lower angular anisotropies than measured for Br and Br{sup ∗}, indicating molecular restructuring during dissociation. The high kinetic energy C{sub 3}H{sub 5} signals are assigned to allyl radicals generated by a minor photochemical pathway which involves concerted C–Br bond dissociation and cyclopropyl ring-opening following single ultraviolet (UV)-photon absorption. Slow photofragments also contribute to the velocity map images obtained at the C{sub 3}H{sub 5} radical mass, but the corresponding slow Br atoms are not observed. These features in the images are attributed to C{sub 3}H{sub 5}{sup +} from the photodissociation of the C{sub 3}H{sub 5}Br{sup +} molecular cation following two-photon ionization of the parent compound. This assignment is confirmed by 118-nm vacuum ultraviolet ionization studies that prepare the molecular cation in its ground electronic state prior to UV photodissociation.

Cross-Modal Perception of Noise-in-Music: Audiences Generate Spiky Shapes in Response to Auditory Roughness in a Novel Electroacoustic Concert Setting.

Science.gov (United States)

Liew, Kongmeng; Lindborg, PerMagnus; Rodrigues, Ruth; Styles, Suzy J

2018-01-01

Noise has become integral to electroacoustic music aesthetics. In this paper, we define noise as sound that is high in auditory roughness, and examine its effect on cross-modal mapping between sound and visual shape in participants. In order to preserve the ecological validity of contemporary music aesthetics, we developed Rama , a novel interface, for presenting experimentally controlled blocks of electronically generated sounds that varied systematically in roughness, and actively collected data from audience interaction. These sounds were then embedded as musical drones within the overall sound design of a multimedia performance with live musicians, Audience members listened to these sounds, and collectively voted to create the shape of a visual graphic, presented as part of the audio-visual performance. The results of the concert setting were replicated in a controlled laboratory environment to corroborate the findings. Results show a consistent effect of auditory roughness on shape design, with rougher sounds corresponding to spikier shapes. We discuss the implications, as well as evaluate the audience interface.

Autour de l’Oedipus chymicus :

Directory of Open Access Journals (Sweden)

Anne-Lise Rey

2008-03-01

Full Text Available A partir de la comparaison entre l’Oedipus chymicus de Leibniz écrit en 1710 et ce qui nous a semblé un possible référent, le texte homonyme de J.J Becher de 1664, l’article s’efforce de déterminer les raisons de l’attrait que Leibniz éprouve pour la chimie de son temps. Si les pratiques de codage et de décodage de la démarche alchimique ainsi que l’attention portée aux transformations des états de la matière constituent indéniablement des points de convergence avec la philosophie leibnizienne, il ne nous semble néanmoins pas possible de conclure de là à une influence de la philosophie chimique, et en particulier de la notion de semence, sur la constitution de la monade leibnizienne.Comparing the Leibniz’s Oedipus chymicus, written in 1710, with its possible reference, the homonymous text by J.J. Becher in 1664, this paper tries to determine why Leibniz had such an interest for the chemistry of his time. If the alchemical practices of coding and decoding and the attention alchemists paid to the modifications of the matter are indeed points of convergence with leibnizian philosophy, it’s nevertheless impossible to conclude to an influence of chemical philosophy, especially of the notion of seed, on the constitution of leibnizian’s monad.

Autour du paradigme d’écotourisme

Directory of Open Access Journals (Sweden)

Anne-Laure Transler

2008-02-01

Full Text Available L’écotourisme ouvre un cadre conceptuel original qui permet d’envisager des démarches renouvelées de développement à partir des revenus issus de consommations touristiques mieux réfléchies et organisées, susceptibles de soutenir des initiatives de développement local s’inscrivant dans un projet global de développement durable. Variante douce du tourisme, loin du tourisme de masse, le champ de l’écotourisme s’étend aux confins du tourisme de nature, du tourisme culturel et des pratiques scientifiques et sportives de plein air. Une définition de l’écotourisme peut être proposée à partir des six points suivants : 1/ nature et culture, 2/ le bien-être des sociétés hôtes, 3/ des touristes responsables, 4/ la participation des sociétés hôtes, 5/ la durabilité, 6/ l’art de la rencontre.Ecotourism provides an original conceptual framework that enables approaches to development that are better able to provide a more equitable distribution of income, as well as better organized and thought through initiatives which are more likely to promote a holistic sustainable local development. With somewhat less negative impact than normal tourism, considerably less that mass tourism, ecotourism can encompass nature tourism, cultural tourism, scientific exploration, and even outdoor sports... A definition of ecotourism should take into account the following six points: 1/ nature and culture, 2/ the welfare of the host community, tourists acting responsibly, 3/ participation by the local community, 5 / sustainability , 6/ promotion of cultural exchanges

To a cultural perspective of mixed reality events: a case study of event overflow in operas and concerts in mixed reality

Science.gov (United States)

Lucas, Jean-François; Cornish, Tracy; Margolis, Todd

2012-12-01

Mixed reality defines the sharing of a space-time between the real and the virtual world. The definition of this concept is further extended when virtual worlds such as Second Life® (SL) are included. Through cultural events such as concerts and operas, we will see that the main goal of these kinds of projects is not simply to offer a video and audio broadcast of these events in the digital dimension. The current challenge is to create interactions between the individuals who are in different shared spaces. By studying the unfolding of these events in its various phases-before, during, and after-we examine the culture of the event. We question how the culture of the event can be transposed in a mixed reality display, and how this kind of event can affect people on both sides of the "membrane" made by the technical configuration. Beyond the alignments and adjustments that we can see between the different individuals involved in these events, we examine more broadly the changes and mutations of the culture of the event in this specific configuration.

Strategy utilized for assessing baseline risks to human health from K-65 and metal oxide residues stored at the Fernald Site

International Nuclear Information System (INIS)

Harmon, J.E.; Janke, R.C.

1995-01-01

The U.S. Department of Energy (DOE) is responsible for cleanup activities at the Fernald Environmental Management Project (FEMP) site in southwestern Ohio. The 425-hectare site consists of a former 55-hectare Production Area, an adjacent Waste Storage Area and various support facilities. From 1952 until 1989, the FEMP processed uranium into metallic open-quotes feedclose quotes materials for other DOE facilities in the nation's defense program. In accordance with the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), the FEMP site is currently listed on the National Priorities List (NPL). To facilitate an expeditious cleanup effort, environmental issues associated with site cleanup are being managed under five operable units. This paper summarizes the risk assessment strategy employed to determine baseline human health risks associated with K-65 and metal oxide residues currently stored in Operable Unit 4. The K-65 and metal oxide residues were generated during the 1950s as a result of the extraction of uranium from uranium-bearing ores and concentrates. These residues are currently stored within Operable Unit 4 in concrete silos. Silos I and 2 contain approximately 6,120 cubic meters [m 3 ] (8,005 cubic yards [yd 3 ]) of K-65 residues, while silos 3 contains approximately 3890 m 3 (5,080 yd 3 ) of cold metal oxides. These concrete silos are beyond their design life and require remedial action. The risk assessment conducted for Operable Unit 4 constitutes the first detailed human health risk assessment to be approved by the Environmental Protection Agency (EPA) for the CERCLA clean-up effort at the FEMP Site. This paper discusses the FEMP's use of a Risk Information Quality Objective process in concert with the traditional risk assessment approach to determine baseline risk to human health and the environment posed by Operable Unit 4. A summary of the baseline risks to human health is also presented

Metabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae

Science.gov (United States)

Mitchell, Sara N.; Rigden, Daniel J.; Dowd, Andrew J.; Lu, Fang; Wilding, Craig S.; Weetman, David; Dadzie, Samuel; Jenkins, Adam M.; Regna, Kimberly; Boko, Pelagie; Djogbenou, Luc; Muskavitch, Marc A. T.; Ranson, Hilary; Paine, Mark J. I.; Mayans, Olga; Donnelly, Martin J.

2014-01-01

The development of resistance to insecticides has become a classic exemplar of evolution occurring within human time scales. In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of both target-site resistance mechanisms that have introgressed between incipient species (the M- and S-molecular forms) and allelic variants in a DDT-detoxifying enzyme. Sequencing of the detoxification enzyme, Gste2, from DDT resistant and susceptible strains of An. gambiae, revealed a non-synonymous polymorphism (I114T), proximal to the DDT binding domain, which segregated with strain phenotype. Recombinant protein expression and DDT metabolism analysis revealed that the proteins from the susceptible strain lost activity at higher DDT concentrations, characteristic of substrate inhibition. The effect of I114T on GSTE2 protein structure was explored through X-ray crystallography. The amino acid exchange in the DDT-resistant strain introduced a hydroxyl group nearby the hydrophobic DDT-binding region. The exchange does not result in structural alterations but is predicted to facilitate local dynamics and enzyme activity. Expression of both wild-type and 114T alleles the allele in Drosophila conferred an increase in DDT tolerance. The 114T mutation was significantly associated with DDT resistance in wild caught M-form populations and acts in concert with target-site mutations in the voltage gated sodium channel (Vgsc-1575Y and Vgsc-1014F) to confer extreme levels of DDT resistance in wild caught An. gambiae. PMID:24675797

Acetic Acid Can Catalyze Succinimide Formation from Aspartic Acid Residues by a Concerted Bond Reorganization Mechanism: A Computational Study

Directory of Open Access Journals (Sweden)

Ohgi Takahashi

2015-01-01

Full Text Available Succinimide formation from aspartic acid (Asp residues is a concern in the formulation of protein drugs. Based on density functional theory calculations using Ace-Asp-Nme (Ace = acetyl, Nme = NHMe as a model compound, we propose the possibility that acetic acid (AA, which is often used in protein drug formulation for mildly acidic buffer solutions, catalyzes the succinimide formation from Asp residues by acting as a proton-transfer mediator. The proposed mechanism comprises two steps: cyclization (intramolecular addition to form a gem-diol tetrahedral intermediate and dehydration of the intermediate. Both steps are catalyzed by an AA molecule, and the first step was predicted to be rate-determining. The cyclization results from a bond formation between the amide nitrogen on the C-terminal side and the side-chain carboxyl carbon, which is part of an extensive bond reorganization (formation and breaking of single bonds and the interchange of single and double bonds occurring concertedly in a cyclic structure formed by the amide NH bond, the AA molecule and the side-chain C=O group and involving a double proton transfer. The second step also involves an AA-mediated bond reorganization. Carboxylic acids other than AA are also expected to catalyze the succinimide formation by a similar mechanism.

Acetic acid can catalyze succinimide formation from aspartic acid residues by a concerted bond reorganization mechanism: a computational study.

Science.gov (United States)

Takahashi, Ohgi; Kirikoshi, Ryota; Manabe, Noriyoshi

2015-01-12

Succinimide formation from aspartic acid (Asp) residues is a concern in the formulation of protein drugs. Based on density functional theory calculations using Ace-Asp-Nme (Ace = acetyl, Nme = NHMe) as a model compound, we propose the possibility that acetic acid (AA), which is often used in protein drug formulation for mildly acidic buffer solutions, catalyzes the succinimide formation from Asp residues by acting as a proton-transfer mediator. The proposed mechanism comprises two steps: cyclization (intramolecular addition) to form a gem-diol tetrahedral intermediate and dehydration of the intermediate. Both steps are catalyzed by an AA molecule, and the first step was predicted to be rate-determining. The cyclization results from a bond formation between the amide nitrogen on the C-terminal side and the side-chain carboxyl carbon, which is part of an extensive bond reorganization (formation and breaking of single bonds and the interchange of single and double bonds) occurring concertedly in a cyclic structure formed by the amide NH bond, the AA molecule and the side-chain C=O group and involving a double proton transfer. The second step also involves an AA-mediated bond reorganization. Carboxylic acids other than AA are also expected to catalyze the succinimide formation by a similar mechanism.

Initiative de recherche concertée sur l'adaptation en Afrique et en Asie

International Development Research Centre (IDRC) Digital Library (Canada)

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Concert club

CERN Multimedia

Concert club

2010-01-01

CERN MEYRIN (terminus bus 56-CERN) entrée B - bâtiment 500 - amphithéâtre mardi 23 mars 2010 à 20 h 30 Eric Schmid, clarinette Muriel Slatkine, piano Au programme : Danzi, Delibes, Gounod, Lovreglio (Verdi), Poulenc, Rossini, Schubert * * * * * samedi 27 mars 2010 à 20 h 30 « Quart de ton » Orchestre et solistes Au programme : Leung Xiao, Lan www.myspace.com/lecardethon * * * * * Dimanche 28 mars 2010 à 17 h 00 et 19 h 00 Rachel Kolly d’Alba, violon Au programme : Bach, Ysaïe * * * * * mardi 30 mars 2010 à 20 h 30 ...

Concert Club

CERN Document Server

Concert Club

2010-01-01

CERN MEYRIN (terminus bus 56-CERN) entrée B - bâtiment 500 - amphithéâtre Mardi 9 Février 2010 à 20 h 30 ”La fontaine aux larmes” Les pays de l’est et le choeur féminin Ensemble vocal féminin Polhymnia Célia Perrard, harpe Camille Girod, flûte Christophe Sturzenegger, piano Quartet Elixir Eléonore Giroud, violon Delphine Touzery, violon Priscille Oehninger, alto Elsa Dorbath, violoncelle Direction : Franck Marcon Au programme : Kodaly – Bartok – Donceanu - Janacek Francesco Hoch (création) ...

Concerts & Opera

Index Scriptorium Estoniae

2006-01-01

Arvo Pärdi teos "Cantus in memoriam Benjamin Britten" esitusel 2. dets. Aldeburghis, Pärdi "Annum per annum" 7. dets. Birminghamis, Kristjan Järvi dirigeerimas 7. dets. Liverpoolis, Neeme Järvi diregeerimas 15. dets. Edinburghis ja 16. dets. Glasgowis

Concerts & Opera

Index Scriptorium Estoniae

2006-01-01

Kammerorkestri Kremerata Baltica kontserdid: 19. apr. Londonis LSO St Lukesis, 21. apr. Oxfordis Sheldonian Theatre'is, 17. apr. Aldeburghis, 20. apr. Manchesteris Bridgewater Hallis, 23. apr. Wales Millennium Centre'is, 22. apr. Edinburghis Usher Hallis

Concert club

CERN Multimedia

2010-01-01

CERN MEYRIN (terminus bus 56-CERN) entrée B - bâtiment 500 - amphithéâtre mardi 9 mars 2010 à 20 h 30 Le trio «Impressions» avec Liliane Jaques, flûte traversière Isabelle Martin-Achard, harpe John Devore, violoncelle Au programme : Bolling, Dewey, Ibert, Vellon, Vellones, Molnar, Andres * * * * * mardi 16 mars 2010 à 20 h 30 Irina Chkourindina, piano Au programme : Chopin, Liszt, Schumann * * * * * vendredi 19 mars 2010 à 20 h 30 Pascal Salomon, piano Au programme : J. Brahms, F.Chopin, M. Ravel, S. Rachmaninoff * * * * * ...

Concerts & Opera

Index Scriptorium Estoniae

2007-01-01

Arvo Pärdi muusika esitusel 4. mail Londonis St Giles Cripplegate'is, 14. mail Queen Elizabeth Hallis, 3. mail Oxfordis; Eesti Filharmoonia Kammerkoor esitab Cyrillus Kreegi "Requiemi" 11. mail Manchesteris Bridgewater Hallis; Olari Elts dirigeerimas 10. mail Edinburghis Usher Hallis, 11. mail Glasgowis ja 12. mail Aberdeenis

Computer analysis of sound recordings from two Anasazi sites in northwestern New Mexico

Science.gov (United States)

Loose, Richard

2002-11-01

Sound recordings were made at a natural outdoor amphitheater in Chaco Canyon and in a reconstructed great kiva at Aztec Ruins. Recordings included computer-generated tones and swept sine waves, classical concert flute, Native American flute, conch shell trumpet, and prerecorded music. Recording equipment included analog tape deck, digital minidisk recorder, and direct digital recording to a laptop computer disk. Microphones and geophones were used as transducers. The natural amphitheater lies between the ruins of Pueblo Bonito and Chetro Ketl. It is a semicircular arc in a sandstone cliff measuring 500 ft. wide and 75 ft. high. The radius of the arc was verified with aerial photography, and an acoustic ray trace was generated using cad software. The arc is in an overhanging cliff face and brings distant sounds to a line focus. Along this line, there are unusual acoustic effects at conjugate foci. Time history analysis of recordings from both sites showed that a 60-dB reverb decay lasted from 1.8 to 2.0 s, nearly ideal for public performances of music. Echoes from the amphitheater were perceived to be upshifted in pitch, but this was not seen in FFT analysis. Geophones placed on the floor of the great kiva showed a resonance at 95 Hz.

Cross-Modal Perception of Noise-in-Music: Audiences Generate Spiky Shapes in Response to Auditory Roughness in a Novel Electroacoustic Concert Setting

Directory of Open Access Journals (Sweden)

Kongmeng Liew

2018-02-01

Full Text Available Noise has become integral to electroacoustic music aesthetics. In this paper, we define noise as sound that is high in auditory roughness, and examine its effect on cross-modal mapping between sound and visual shape in participants. In order to preserve the ecological validity of contemporary music aesthetics, we developed Rama, a novel interface, for presenting experimentally controlled blocks of electronically generated sounds that varied systematically in roughness, and actively collected data from audience interaction. These sounds were then embedded as musical drones within the overall sound design of a multimedia performance with live musicians, Audience members listened to these sounds, and collectively voted to create the shape of a visual graphic, presented as part of the audio–visual performance. The results of the concert setting were replicated in a controlled laboratory environment to corroborate the findings. Results show a consistent effect of auditory roughness on shape design, with rougher sounds corresponding to spikier shapes. We discuss the implications, as well as evaluate the audience interface.

Decline of a Rare Moth at Its Last Known English Site: Causes and Lessons for Conservation.

Directory of Open Access Journals (Sweden)

David Baker

Full Text Available The conditions required by rare species are often only approximately known. Monitoring such species over time can help refine management of their protected areas. We report population trends of a rare moth, the Dark Bordered Beauty Epione vespertaria (Linnaeus, 1767 (Lepidoptera: Geometridae at its last known English site on a protected lowland heath, and those of its host-plant, Salix repens (L. (Malpighiales: Salicaceae. Between 2007 and 2014, adult moth density reduced by an average of 30-35% annually over the monitored area, and its range over the monitored area contracted in concert. By comparing data from before this decline (2005 with data taken in 2013, we show that the density of host-plants over the monitored area reduced three-fold overall, and ten-fold in the areas of highest host-plant density. In addition, plants were significantly smaller in 2013. In 2005, moth larvae tended to be found on plants that were significantly larger than average at the time. By 2013, far fewer plants were of an equivalent size. This suggests that the rapid decline of the moth population coincides with, and is likely driven by, changes in the host-plant population. Why the host-plant population has changed remains less certain, but fire, frost damage and grazing damage have probably contributed. It is likely that a reduction in grazing pressure in parts of the site would aid host-plant recovery, although grazing remains an important site management activity. Our work confirms the value of constant monitoring of rare or priority insect species, of the risks posed to species with few populations even when their populations are large, of the potential conflict between bespoke management for species and generic management of habitats, and hence the value of refining our knowledge of rare species' requirements so that their needs can be incorporated into the management of protected areas.

Securite, dangerosite, biopolitique: trois versants d'une nouvelle pratique de pouvoir sur les individus

Directory of Open Access Journals (Sweden)

Jean-François Bert

2012-01-01

Full Text Available Le questionnement de Foucault sur la judiciarisation des sociétés contemporaines renvoie à plusieurs controverses qui, entre 1974 et 1976, ont spécifiquement concerné la question du vivant comme de son rapport au champ du droit et des institutions politiques. Ces polémiques se sont cristallisées autour d'affaires judiciaires retentissantes mais également autour d'un discours technique et politique qui donne une place nouvelle aux notions de dangerosité, de sécurité et à la question plus générale de la gestion du vivant. Trois discours qui, pour Foucault, sont révélateur d'un profond changement de société et de mode de gouvernement des individus.

The concerted impact of galaxies and QSOs on the ionization and thermal state of the intergalactic medium

Science.gov (United States)

Kakiichi, Koki; Graziani, Luca; Ciardi, Benedetta; Meiksin, Avery; Compostella, Michele; Eide, Marius B.; Zaroubi, Saleem

2017-07-01

We present a detailed analysis of the ionization and thermal structure of the intergalactic medium (IGM) around a high-redshift (z = 10) QSO, using a large suite of cosmological, multifrequency radiative transfer simulations, exploring the contribution from galaxies as well as the QSO, and the effect of X-rays and secondary ionization. We show that in high-z QSO environments both the central QSO and the surrounding galaxies concertedly control the reionization morphology of hydrogen and helium and have a non-linear impact on the thermal structure of the IGM. A QSO imprints a distinctive morphology on H II regions if its total ionizing photon budget exceeds that of the surrounding galaxies since the onset of hydrogen reionization; otherwise, the morphology shows little difference from that of H II regions produced only by galaxies. In addition, the spectral shape of the collective radiation field from galaxies and QSOs controls the thickness of the I-fronts. While a UV-obscured QSO can broaden the I-front, the contribution from other UV sources, either galaxies or unobscured QSOs, is sufficient to maintain a sharp I-front. X-ray photons from the QSO are responsible for a prominent extended tail of partial ionization ahead of the I-front. QSOs leave a unique imprint on the morphology of He II/He III regions. We suggest that, while the physical state of the IGM is modified by QSOs, the most direct test to understand the role of galaxies and QSOs during reionization is to perform galaxy surveys in a region of sky imaged by 21 cm tomography.

Global site-specific analysis of glycoprotein N-glycan processing.

Science.gov (United States)

Cao, Liwei; Diedrich, Jolene K; Ma, Yuanhui; Wang, Nianshuang; Pauthner, Matthias; Park, Sung-Kyu Robin; Delahunty, Claire M; McLellan, Jason S; Burton, Dennis R; Yates, John R; Paulson, James C

2018-06-01

N-glycans contribute to the folding, stability and functions of the proteins they decorate. They are produced by transfer of the glycan precursor to the sequon Asn-X-Thr/Ser, followed by enzymatic trimming to a high-mannose-type core and sequential addition of monosaccharides to generate complex-type and hybrid glycans. This process, mediated by the concerted action of multiple enzymes, produces a mixture of related glycoforms at each glycosite, making analysis of glycosylation difficult. To address this analytical challenge, we developed a robust semiquantitative mass spectrometry (MS)-based method that determines the degree of glycan occupancy at each glycosite and the proportion of N-glycans processed from high-mannose type to complex type. It is applicable to virtually any glycoprotein, and a complete analysis can be conducted with 30 μg of protein. Here, we provide a detailed description of the method that includes procedures for (i) proteolytic digestion of glycoprotein(s) with specific and nonspecific proteases; (ii) denaturation of proteases by heating; (iii) sequential treatment of the glycopeptide mixture with two endoglycosidases, Endo H and PNGase F, to create unique mass signatures for the three glycosylation states; (iv) LC-MS/MS analysis; and (v) data analysis for identification and quantitation of peptides for the three glycosylation states. Full coverage of site-specific glycosylation of glycoproteins is achieved, with up to thousands of high-confidence spectra hits for each glycosite. The protocol can be performed by an experienced technician or student/postdoc with basic skills for proteomics experiments and takes ∼7 d to complete.

Seismic-reflection and ground penetrating radar for environmental site characterization. 1998 annual progress report

International Nuclear Information System (INIS)

Plumb, R.; Steeples, D.W.

1998-01-01

'The project''s goals are threefold: (1) to examine the complementary site-characterization capabilities of modern, three-component shallow-seismic techniques and ground-penetrating radar (GPR) methods at depths ranging from 2 to 8 m at an existing test site; (2) to demonstrate the usefulness of the two methods when used in concert to characterize, in three-dimensions, the cone of depression of a pumping well, which will serve as a proxy site for fluid-flow at an actual, polluted site; and (3) to use the site as an outdoor mesoscale laboratory to validate existing three-dimensional ground-penetrating radar and seismic-reflection computer models developed at the Univ. of Kansas. To do this, useful seismic and GPR data are being collected along the same line(s) and within the same depth range. The principal investigators selected a site in central Kansas as a primary location and, although the site itself is not environmentally sensitive, the location chosen offers particularly useful attributes for this research and will serve as a proxy site for areas that are contaminated. As part of an effort to evaluate the strengths of each method, the authors will repeat the seismic and GPR surveys on a seasonal basis to establish how the complementary information obtained varies over time. Because the water table fluctuates at this site on a seasonal basis, variations in the two types of data over time also can be observed. Such noninvasive in-situ methods of identifying and characterizing the hydrologic flow regimes at contaminated sites support the prospect of developing effective, cost-conscious cleanup strategies in the near future. As of the end of May 1998, the project is on schedule. The first field work was conducted using both of the geophysical survey methods in October of 1997, and the second field survey employed both methods in March of 1998. One of the stated tasks is to reoccupy the same survey line on a quarterly basis for two years to examine change in both

Site specific information in site selection

International Nuclear Information System (INIS)

Aeikaes, T.; Hautojaervi, A.

1998-01-01

The programme for the siting of a deep repository for final disposal of spent nuclear fuel was started already in 1983 and is carried out today by Posiva Oy which continues the work started by Teollisuuden Voima Oy. The programme aims at site selection by the end of the year 2000. The programme has progressed in successive interim stages with defined goals. After an early phase for site identification, five sites were selected in 1987 for preliminary site characterisation. Three of these were selected and judged to be best suited for the more detailed characterisation in 1992. An additional new site was included into the programme based on a separate feasibility study in the beginning of 1997. Since the year 1983 several safety assessments together with technical plans of the facility have been completed. When approaching the site selection the needs for more detailed consideration of the site specific properties in the safety assessment have been increased. The Finnish regulator STUK has published a proposal for general safety requirements for the final disposal of spent nuclear fuel in Finland. This set of requirements has been projected to be used in conjunction of the decision making by the end 2000. Based on the site evaluation all sites can provide a stable environment and there is evidence that the requirements for the longevity of the canister can be fulfilled at each site. In this manner the four candidate sites do not differ too much from each other. The main difference between the sites is in the salinity of the deep groundwater. The significance of differences in the salinity for the long-term safety cannot be defined yet. The differences may contribute to the discussion of the longevity of the bentonite buffer and also to the modelling of the groundwater flow and transport. The use of the geosphere as a transport barrier is basically culminated on the questions about sparse but fast flow routes and 'how bad channeling can be'. To answer these questions

Publication Of Administrative Circulars: No. 4 (Rev. 4) – Unemployment Insurance Scheme No. 30 (Rev. 2) – Financial Benefits on Taking Up Appointment and on Termination of Contract

CERN Multimedia

HR Department

2008-01-01

Administrative Circular No. 4 (Rev. 4) – Unemployment insurance scheme Administrative Circular No. 4 (Rev. 4) – "Unemployment insurance scheme", approved following discussion in the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources Department. It cancels and replaces Administrative Circular No. 4 (Rev. 3) – "Unemployment insurance" of October 1993. Copies will shortly be available in Departmental secretariats. Human Resources Department Tel. 78003 Administrative Circular No. 30 (Rev. 2) – Financial benefits on taking up appointment and termination of contract Administrative Circular No. 30 (Rev. 2) – "Financial benefits on taking up appointment and termination of contract", approved following discussion in the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources De...

Publication Of Administrative Circulars: No. 4 (Rev. 4) – Unemployment Insurance Scheme No. 30 (Rev. 2) – Financial Benefits on Taking Up Appointment and on Termination of Contract

CERN Document Server

HR Department

2008-01-01

Administrative Circular No. 4 (Rev. 4) – Unemployment insurance scheme Administrative Circular No. 4 (Rev. 4) – "Unemployment insurance scheme", approved following discussion at the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources Department. It cancels and replaces Administrative Circular No. 4 (Rev. 3) – "Unemployment insurance" of October 1993. Copies will shortly be available in Departmental secretariats. Human Resources Department Tel. 78003 Administrative Circular No. 30 (Rev. 2) – Financial benefits on taking up appointment and termination of contract Administrative Circular No. 30 (Rev. 2) – "Financial benefits on taking up appointment and termination of contract", approved following discussion at the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources De...

New Media and Music Products "Any Place and Any Time"

DEFF Research Database (Denmark)

Stöber, Birgit

that underpin traditional forms of cultural and social interaction and thus the relationship between place, community and identity.” (Dodge & Kitchen 2001, 33) Moreover, an argument often heard is that media are not able to reproduce a unique moment tied to a particular site; therefore media (no matter whether...... authentic concert experience on a home computer” (Kolbe 2009, 12). However, the DCH is extremely bounded to the concrete place of the concert hall in Berlin mainly due to the technology installed in the hall. In this paper, I will argue that the virtual place of the DCH is a new media initiative from...

Site organization and site arrangement

International Nuclear Information System (INIS)

Boissonnet, B.; Macqueron, J.F.

1976-01-01

The present paper deals with criteria for the choice of a production unit or power plant site, the organization and development of a site in terms of its particular characteristics and takes into account personnel considerations in site organizations as well as the problem of integrating the architecture into the environment. (RW) [de

Strategy utilized for assessing baseline risks to human health from K-65 and metal oxide residues stored at the Fernald Site

Energy Technology Data Exchange (ETDEWEB)

Harmon, J.E. [FERMCO, Cincinnati, OH (United States). Fernald Environmental Management Project; Janke, R.C.

1995-04-01

The U.S. Department of Energy (DOE) is responsible for cleanup activities at the Fernald Environmental Management Project (FEMP) site in southwestern Ohio. The 425-hectare site consists of a former 55-hectare Production Area, an adjacent Waste Storage Area and various support facilities. From 1952 until 1989, the FEMP processed uranium into metallic {open_quotes}feed{close_quotes} materials for other DOE facilities in the nation`s defense program. In accordance with the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), the FEMP site is currently listed on the National Priorities List (NPL). To facilitate an expeditious cleanup effort, environmental issues associated with site cleanup are being managed under five operable units. This paper summarizes the risk assessment strategy employed to determine baseline human health risks associated with K-65 and metal oxide residues currently stored in Operable Unit 4. The K-65 and metal oxide residues were generated during the 1950s as a result of the extraction of uranium from uranium-bearing ores and concentrates. These residues are currently stored within Operable Unit 4 in concrete silos. Silos I and 2 contain approximately 6,120 cubic meters [m{sup 3}] (8,005 cubic yards [yd{sup 3}]) of K-65 residues, while silos 3 contains approximately 3890 m{sup 3} (5,080 yd{sup 3}) of cold metal oxides. These concrete silos are beyond their design life and require remedial action. The risk assessment conducted for Operable Unit 4 constitutes the first detailed human health risk assessment to be approved by the Environmental Protection Agency (EPA) for the CERCLA clean-up effort at the FEMP Site. This paper discusses the FEMP`s use of a Risk Information Quality Objective process in concert with the traditional risk assessment approach to determine baseline risk to human health and the environment posed by Operable Unit 4. A summary of the baseline risks to human health is also presented.

European concerted action on offshore wind energy deployment: inventory and analysis of power transmission barriers in eight member states

International Nuclear Information System (INIS)

Woyte, Achim; Gardner, Paul; Snodin, Helen

2007-01-01

The European Concerted Action for Offshore Wind Energy Deployment (COD) was carried out by eight sea-bordering European Union member states, with the objective to remove not explicitly technical barriers to offshore wind energy. Within the COD, an inventory of relevant aspects affecting the grid integration of offshore wind energy on a large scale in the eight countries has been made. Collected data items for this inventory are national plans and prospects for offshore wind energy, information about the transmission system, possibilities for grid connection, aspects of the grid codes, balancing, connection and energy pricing. The comprehensive COD reports were published and presented in October 2005 during the Copenhagen Offshore wind conference. This paper provides a short description of the situation for each country. Thereafter, country-specific information is grouped based on geography and membership in a synchronous zone. Additionally, a view is developed on the desirable facilities for the trans-European exchange of power from large wind farms. Finally, we elaborate overall conclusions in order to arrive at generalized observations, recommendations for policy makers and issues that will emerge in the near future. As a general conclusion, many things need to be done on a technical level in order to integrate large amounts of offshore wind power into our power systems. However, none of these measures is technically unknown. Therefore, the feasibility of integrating large amounts of offshore wind power is mainly a question of finance and hence based on political decisions. (Author)

The evolution of increased competitive ability, innate competitive advantages, and novel biochemical weapons act in concert for a tropical invader.

Science.gov (United States)

Qin, Rui-Min; Zheng, Yu-Long; Valiente-Banuet, Alfonso; Callaway, Ragan M; Barclay, Gregor F; Pereyra, Carlos Silva; Feng, Yu-Long

2013-02-01

There are many non-mutually exclusive mechanisms for exotic invasions but few studies have concurrently tested more than one hypothesis for the same species. Here, we tested the evolution of increased competitive ability (EICA) hypothesis in two common garden experiments in which Chromolaena odorata plants originating from native and nonnative ranges were grown in competition with natives from each range, and the novel weapons hypothesis in laboratory experiments with leachates from C. odorata. Compared with conspecifics originating from the native range, C. odorata plants from the nonnative range were stronger competitors at high nutrient concentrations in the nonnative range in China and experienced far more herbivore damage in the native range in Mexico. In both China and Mexico, C. odorata was more suppressed by species native to Mexico than by species native to China. Species native to China were much more inhibited by leaf extracts from C. odorata than species from Mexico, and this difference in allelopathic effects may provide a possible explanation for the biogeographic differences in competitive ability. Our results indicate that EICA, innate competitive advantages, and novel biochemical weapons may act in concert to promote invasion by C. odorata, and emphasize the importance of exploring multiple, non-mutually exclusive mechanisms for invasions. © 2012 The Authors. New Phytologist © 2012 New Phytologist Trust.

Interfon

CERN Multimedia

Interfon

2013-01-01

www.interfon.fr   Rendez-vous sur notre site pour toutes les « News » Interfon « News »   Derniers rappels importants   Le mercredi 9 octobre 2013 Salle Jean Monnet à Saint-Genis-Pouilly de 16 h 00 à 20 h 00 Rencontrez nos partenaires. Venez nous rejoindre et découvrir nos fournisseurs autour d’un buffet campagnard. Commandez votre fioul au tarif spécial « Portes ouvertes », dégustez et commandez notre sélection de vins et champagnes. «Tarifs préférentiels » Offre promotionnelle Vitam’ Pour les visiteurs de notre Portes Ouvertes : – Pour + de 80 € de billets Vitam’ achetés*, recevez en cadeau 1 entrée au choix « Aquatique ou Escalade (enfant ou adulte) ou raquettes ». &ndas...

Examination of vegetation around a nuclear plant emitting gaseous fluorides in order to detect fluorine pollution; Utilisation des vegetaux pour detecter la pollution fluoree autour d'une usine susceptible d'emettre des effluents gazeux fluores

Energy Technology Data Exchange (ETDEWEB)

Teulon, Francoise; Bonnaventure, J. P. [Commissariat a l' energie atomique et aux energies alternatives - CEA, Centre de Pierrelatte, Section de Protection contre les Radiations (France)

1971-08-15

Fluorine pollution (chronic or occasional) around a plant rejecting gaseous fluoride effluents can be detected from vegetation samples by chemical analysis. Systematic monitoring allows the effects and gravity of the pollution to be estimated. The analytical method used consists of a double distillation (in phosphoric acid and perchloric acid) followed by a spectro-colorimetric analysis (alizarine-complexon-lanthane). This method of control allows both the efficiency of the trapping installations and also the appearance of effluents at unexpected places to be checked, In the event of an accident it is possible to determine the advisability of prohibiting the consumption of locally grown produce by humans or fodder by cattle. Research conducted in order to determine the relation between visible, damage to certain vegetables (tomatoes, haricot beans and sorghum) and their fluorine contents demonstrated that such a relation appears above all at the level of the leaves; chemical analysis may thus be used to confirm or reject information obtained on the basis of visual evidence [French] La detection d'une pollution fluoree (chronique ou accidentelle) autour d'une usine susceptible d'emettre des effluents gazeux fluores peut etre avantageusement realisee par un reseau de prelevements vegetaux suivis de dosages chimiques. Une surveillance systematique permet une evaluation des consequences et du degre de gravite de la pollution. La methode d'analyse consiste en une double distillation (dans l'acide phosphorique et l'acide perchlorique) suivie d'une spectrocolorimetrie (alizarine-complexon-lanthane). Ce mode de controle permet non seulement de verifier si les installations de piegeage sont efficaces mais egalement de localiser des points d'emission imprevus. En cas d'accident, on peut egalement juger de l'opportunite d'interdire la consommation des legumes par les habitants ou du fourrage par le betail des environs. Enfin, des etudes experimentales ont ete realisees pour

Klebsiella aerogenes UreF: Identification of the UreG Binding Site and Role in Enhancing the Fidelity of Urease Activation†

Science.gov (United States)

Boer, Jodi L.; Hausinger, Robert P.

2012-01-01

The Ni-containing active site of Klebsiella aerogenes urease is assembled through the concerted action of the UreD, UreE, UreF, and UreG accessory proteins. UreE functions as a metallochaperone that delivers Ni to a complex of UreD—UreF—UreG bound to urease apoprotein, with UreG serving as a GTPase during enzyme activation. The present study focuses on the role of UreF, previously proposed to act as a GTPase activating protein (GAP) of UreG. Sixteen conserved UreF surface residues that may play roles in protein:protein interactions were independently changed to Ala. When produced in the context of the entire urease gene cluster, cell-free extracts of nine site-directed mutants had less than 10% of the wild-type urease activity. Enrichment of the variant forms of UreF, as the UreE-F fusion proteins, uniformly resulted in co-purification of UreD and urease apoprotein; whereas UreG bound to only a subset of the species. Notably, reduced interaction with UreG correlated with the low activity mutants. The affected residues in UreF map to a distinct surface on the crystal structure, defining the UreG binding site. In contrast to the hypothesis that UreF is a GAP, the UreD—UreF—UreG—urease apoprotein complex containing K165A UreF exhibited significantly greater levels of GTPase activity than that containing the wild-type protein. Additional studies demonstrated the UreG GTPase activity was largely uncoupled from urease activation for the complex containing this UreF variant. Further experiments with these complexes provided evidence that UreF gates the GTPase activity of UreG to enhance the fidelity of urease metallocenter assembly, especially in the presence of the non-cognate metal Zn. PMID:22369361

Early Site Permit Demonstration Program: Siting Guide, Site selection and evaluation criteria for an early site permit application

International Nuclear Information System (INIS)

1993-01-01

In August 1991, the Joint Contractors came to agreement with Sandia National Laboratories (SNL) and the Department of Energy (DOE) on a workscope for the cost-shared Early Site Permit Demonstration Program. One task within the scope was the development of a guide for site selection criteria and procedures. A generic Siting Guide his been prepared that is a roadmap and tool for applicants to use developing detailed siting plans for their specific region of the country. The guide presents three fundamental principles that, if used, ensure a high degree of success for an ESP applicant. First, the site selection process should take into consideration environmentally diverse site locations within a given region of interest. Second, the process should contain appropriate opportunities for input from the public. Third, the process should be applied so that it is clearly reasonable to an impartial observer, based on appropriately selected criteria, including criteria which demonstrate that the site can host an advanced light water reactor (ALWR). The Siting Guide provides for a systematic, comprehensive site selection process in which three basic types of criteria (exclusionary, avoidance, and suitability) are presented via a four-step procedure. It provides a check list of the criteria for each one of these steps. Criteria are applied qualitatively, as well as presented numerically, within the guide. The applicant should use the generic guide as an exhaustive checklist, customizing the guide to his individual situation

Inter-subunit interactions across the upper voltage sensing-pore domain interface contribute to the concerted pore opening transition of Kv channels.

Directory of Open Access Journals (Sweden)

Tzilhav Shem-Ad

Full Text Available The tight electro-mechanical coupling between the voltage-sensing and pore domains of Kv channels lies at the heart of their fundamental roles in electrical signaling. Structural data have identified two voltage sensor pore inter-domain interaction surfaces, thus providing a framework to explain the molecular basis for the tight coupling of these domains. While the contribution of the intra-subunit lower domain interface to the electro-mechanical coupling that underlies channel opening is relatively well understood, the contribution of the inter-subunit upper interface to channel gating is not yet clear. Relying on energy perturbation and thermodynamic coupling analyses of tandem-dimeric Shaker Kv channels, we show that mutation of upper interface residues from both sides of the voltage sensor-pore domain interface stabilizes the closed channel state. These mutations, however, do not affect slow inactivation gating. We, moreover, find that upper interface residues form a network of state-dependent interactions that stabilize the open channel state. Finally, we note that the observed residue interaction network does not change during slow inactivation gating. The upper voltage sensing-pore interaction surface thus only undergoes conformational rearrangements during channel activation gating. We suggest that inter-subunit interactions across the upper domain interface mediate allosteric communication between channel subunits that contributes to the concerted nature of the late pore opening transition of Kv channels.

Inter-subunit interactions across the upper voltage sensing-pore domain interface contribute to the concerted pore opening transition of Kv channels.

Science.gov (United States)

Shem-Ad, Tzilhav; Irit, Orr; Yifrach, Ofer

2013-01-01

The tight electro-mechanical coupling between the voltage-sensing and pore domains of Kv channels lies at the heart of their fundamental roles in electrical signaling. Structural data have identified two voltage sensor pore inter-domain interaction surfaces, thus providing a framework to explain the molecular basis for the tight coupling of these domains. While the contribution of the intra-subunit lower domain interface to the electro-mechanical coupling that underlies channel opening is relatively well understood, the contribution of the inter-subunit upper interface to channel gating is not yet clear. Relying on energy perturbation and thermodynamic coupling analyses of tandem-dimeric Shaker Kv channels, we show that mutation of upper interface residues from both sides of the voltage sensor-pore domain interface stabilizes the closed channel state. These mutations, however, do not affect slow inactivation gating. We, moreover, find that upper interface residues form a network of state-dependent interactions that stabilize the open channel state. Finally, we note that the observed residue interaction network does not change during slow inactivation gating. The upper voltage sensing-pore interaction surface thus only undergoes conformational rearrangements during channel activation gating. We suggest that inter-subunit interactions across the upper domain interface mediate allosteric communication between channel subunits that contributes to the concerted nature of the late pore opening transition of Kv channels.

Protein SIC Secreted fromForms Complexes with Extracellular Histones That Boost Cytokine Production

DEFF Research Database (Denmark)

Westman, Johannes; Chakrakodi, Bhavya; Snäll, Johanna

2018-01-01

Innate immunity relies on an effective recognition of the pathogenic microorganism as well as on endogenous danger signals. While bacteria in concert with their secreted virulence factors can cause a number of inflammatory reactions, danger signals released at the site of infection may in additio...

Site Closure Strategy Model for Creosote Site

International Nuclear Information System (INIS)

Coll, F.R.; Gray, D.R.

2009-01-01

In conjunction with RCRA site corrective action at an active wood preserving facility, a risk-based site closure strategy was developed and incorporated the performance of a dense non-aqueous phase liquid (DNAPL) source recovery remedy, a monitored natural attenuation (MNA) remedy for dissolved phase groundwater, and institutional controls. Innovative creosote DNAPL source recovery has been undertaken at the Site since 1998. Pooled creosote DNAPL is present 90 feet below ground within a transmissive sand and gravel aquifer with a saturated thickness of approximately 80 feet. The creosote DNAPL source is situated on the property boundary of the site and has generated a 1/2 mile off-site dissolved phase plume, creating significant NAPL management and remedial technology verification issues. To date, over 120,000 gallons of creosote DNAPL have been recovered from the subsurface utilizing a modified circulation well technology. A mass discharge flux protocol was developed to serve as a major performance metrics for the continuation of source removal efforts and to support the application of monitored natural attenuation as an associated remedial technology for groundwater. The mass removal success has supported the MNA remedy for dissolved phase groundwater and the associated development of institutional controls. The enacted site management strategy outlines the current and future risk management activities for the Site and represents an appropriate site closure strategy for the Site. (authors)

Diathesis sotto tensione. La sala per concerti del Centro culturale di Atene di Jan Despo / Diathesis under Tension. Concert Theatre of the Athens Cultural Center by Jan Despo

Directory of Open Access Journals (Sweden)

Tilemachos Adrianopoulos

2016-04-01

Full Text Available Nel 1959, l'architetto greco Jan Despo (1903-1992 fu insignito del primo premio nella competizione per il Centro culturale di Atene, rimasto irrealizzato eccezion fatta per il Conservatorio di Atene. La sala circolare per concerti, danza e conferenze era l'edificio nodale di una ambiziosa composizione urbana: la sbalorditiva forma geometrica della sala, la funzione tipicamente composita e l'ingegnosa conformazione strutturale furono integralmente concepite all'interno di una "diathesis spaziale". / In 1959, Greek architect Jan Despo (1903-1992 was awarded First Prize in the competition for the Athens Cultural Centre -that remained unrealized, however, with the exception of the Athens Conservatory. The circular concert, dance and conference theatre was the nodal building of an ambitious urban composition: the theatre’s stunning geometric form, distinctively composite function and ingenious structural conformation were all integrally conceived—within an essentially tense spatial diathesis.

Study of site layout in the Rokkasho site

International Nuclear Information System (INIS)

Sato, Kazuyoshi; Tamura, Kousaku; Yagenji, Akira; Sekiya, Shigeki; Takahashi, Hideo; Neyatani, Yuzuru; Uehara, Masaharu; Motohashi, Keiichi; Hashimoto, Masayoshi; Ogino, Shunji; Nagamatsu, Nobuhide

2006-03-01

The Final Design Report (FDR) of the International Thermonuclear Experimental Reactor (ITER) was published on July 2001 as a summary of the Engineering Design Activity (EDA). After the EDA, site dependent design has been investigated for the invitation of ITER toward Rokkasho Site (Iyasakadai area) in Aomori prefecture. This report describes the results of site layout of major buildings and structures of ITER in the Rokkasho-Site. The data of the ground near the site and the results of site dependent design in Japan were applied to this study. Through this study, the most appropriate site layout has been constructed with satisfaction of following conditions. (1) Bedrock level at the tokamak complex building is relatively high and it can be reduced the cost of excavation and foundation work. (2) Total amount of excavation soil for site preparation is minimized and the flexibility of the layout is ensured with flat ground level. (3) Accessibility of human and equipments, reduction of noise and vibration to the environment can be obtained. Total length of ducts and piping between buildings in site is minimized. (author)

Modélisation et simulation numérique du comportement vibratoire ...

African Journals Online (AJOL)

HP 250

Modeling and numerical simulation of gear vibratory behavior ... Une étude paramétrique a été réalisée sous Matlab pour ..... fissure sur le signal de vibration est la modulation d‟amplitude autour de la fréquence d‟ .... Signal Process, Vol.

Standing Concertation Committee

CERN Document Server

HR Department

2009-01-01

Main points examined at the meeting of 24 June 2009 Results of the 2009 MARS exercise The Committee took note of the results of the 2009 MARS exercise presented by the Head of the HR Department, expressing satisfaction for the early availability of the statistics and for the fact that the analysis of the results covered the last three years. Status report on the work on the five-yearly review The Committee took note of a presentation by P. Gildemyn on the data collection procedure for the 2010 five-yearly review (staff, fellows, associate members of the personnel, CHIS) and of the proposed work schedule. Implications for employment conditions of the discussions at the Finance Committee and Council on 17 and 18 June 2009 The Chairman briefly reported on the discussions at the meetings of the Finance Committee and Council in June 2009, on the 2010-2014 medium-term plan and the 2010 preliminary draft budget, as well as on the modified strategy and goals for 2009. The Committee ...

Thinking-in-Concert

Science.gov (United States)

O'Donnell, Aislinn

2012-01-01

In this essay, I examine the concept of thinking in Hannah Arendt's writings. Arendt's interest in the experience of thinking allowed her to develop a concept of thinking that is distinct from other forms of mental activity such as cognition and problem solving. For her, thinking is an unending, unpredictable and destructive activity without fixed…

Plasmin substrate binding site cooperativity guides the design of potent peptide aldehyde inhibitors.

Science.gov (United States)

Swedberg, Joakim E; Harris, Jonathan M

2011-10-04

Perioperative bleeding is a cause of major blood loss and is associated with increased rates of postoperative morbidity and mortality. To combat this, antifibrinolytic inhibitors of the serine protease plasmin are commonly used to reduce bleeding during surgery. The most effective and previously widely used of these is the broad range serine protease inhibitor aprotinin. However, adverse clinical outcomes have led to use of alternative serine lysine analogues to inhibit plasmin. These compounds suffer from low selectivity and binding affinity. Consequently, a concerted effort to discover potent and selective plasmin inhibitors has developed. This study used a noncombinatorial peptide library to define plasmin's extended substrate specificity and guide the design of potent transition state analogue inhibitors. The various substrate binding sites of plasmin were found to exhibit a higher degree of cooperativity than had previously been appreciated. Peptide sequences capitalizing on these features produced high-affinity inhibitors of plasmin. The most potent of these, Lys-Met(sulfone)-Tyr-Arg-H [KM(O(2))YR-H], inhibited plasmin with a K(i) of 3.1 nM while maintaining 25-fold selectivity over plasma kallikrein. Furthermore, 125 nM (0.16 μg/mL) KM(O(2))YR-H attenuated fibrinolysis in vitro with an efficacy similar to that of 15 nM (0.20 μg/mL) aprotinin. To date, this is the most potent peptide inhibitor of plasmin that exhibits selectivity against plasma kallikrein, making this compound an attractive candidate for further therapeutic development.

Nuclear wastes management: the lessons from the C.S.M. disposal site (Centre de Stockage de la Manche. Memory-less Centre, Future-less Centre?

International Nuclear Information System (INIS)

2006-05-01

With its 527 217 m 3 of low and medium activity wastes put in storage between 1969 and 1994, the C.S.M.( center of storage of Manche) is and remains to this day a necessary element to understand the problems posed by the eternal storage of nuclear materials and the limits of the notion of reversibility. There are therefore teachings to be drawn. We cannot repeat past mistakes in particular with high activity wastes which we wish to bury deep underground. This report is based on the analysis of the existing bibliography, of the internal A.N.D.R.A. documents which we released to the public, of the lessons drawn from our participation in the official concerting and work groups, and finally of the data obtained after inquiries were done in the region in the framework of R.I.V.I.E;R.E. (citizens network of radioecological surveillance, information and evaluation). In spite of all efforts produced, many questions remain unanswered regarding this site so it is sometimes difficult to be more precise. (N.C.)

Theory for site-site pair distribution functions of molecular fluids. II. Approximations for the Percus--Yevick site-site direct correlation functions

International Nuclear Information System (INIS)

Johnson, E.

1977-01-01

A theory for site-site pair distribution functions of molecular fluids is derived from the Ornstein-Zernike equation. Atom-atom pair distribution functions of this theory which were obtained by using different approximations for the Percus-Yevick site-site direct correlation functions are compared

Armed Deterrence: Countering Soft Target Attacks

Science.gov (United States)

2016-02-06

offer no security. With over 17,430 such geographically separated military sites across the United States, these fatal shootings by a Kuwaiti- born ...increasing trend and the carnage 4 that IS sympathizers can unleash. This coordinated attack on a concert hall, a soccer stadium, and restaurant

SitesIdentify: a protein functional site prediction tool

Directory of Open Access Journals (Sweden)

Doig Andrew J

2009-11-01

Full Text Available Abstract Background The rate of protein structures being deposited in the Protein Data Bank surpasses the capacity to experimentally characterise them and therefore computational methods to analyse these structures have become increasingly important. Identifying the region of the protein most likely to be involved in function is useful in order to gain information about its potential role. There are many available approaches to predict functional site, but many are not made available via a publicly-accessible application. Results Here we present a functional site prediction tool (SitesIdentify, based on combining sequence conservation information with geometry-based cleft identification, that is freely available via a web-server. We have shown that SitesIdentify compares favourably to other functional site prediction tools in a comparison of seven methods on a non-redundant set of 237 enzymes with annotated active sites. Conclusion SitesIdentify is able to produce comparable accuracy in predicting functional sites to its closest available counterpart, but in addition achieves improved accuracy for proteins with few characterised homologues. SitesIdentify is available via a webserver at http://www.manchester.ac.uk/bioinformatics/sitesidentify/

Early Site Permit Demonstration Program: Siting Guide, Site selection and evaluation criteria for an early site permit application. Revision 1

Energy Technology Data Exchange (ETDEWEB)

1993-03-24

In August 1991, the Joint Contractors came to agreement with Sandia National Laboratories (SNL) and the Department of Energy (DOE) on a workscope for the cost-shared Early Site Permit Demonstration Program. One task within the scope was the development of a guide for site selection criteria and procedures. A generic Siting Guide his been prepared that is a roadmap and tool for applicants to use developing detailed siting plans for their specific region of the country. The guide presents three fundamental principles that, if used, ensure a high degree of success for an ESP applicant. First, the site selection process should take into consideration environmentally diverse site locations within a given region of interest. Second, the process should contain appropriate opportunities for input from the public. Third, the process should be applied so that it is clearly reasonable to an impartial observer, based on appropriately selected criteria, including criteria which demonstrate that the site can host an advanced light water reactor (ALWR). The Siting Guide provides for a systematic, comprehensive site selection process in which three basic types of criteria (exclusionary, avoidance, and suitability) are presented via a four-step procedure. It provides a check list of the criteria for each one of these steps. Criteria are applied qualitatively, as well as presented numerically, within the guide. The applicant should use the generic guide as an exhaustive checklist, customizing the guide to his individual situation.

Preliminary siting characterization Salt Disposition Facility - Site B

International Nuclear Information System (INIS)

Wyatt, D.

2000-01-01

A siting and reconnaissance geotechnical program has been completed in S-Area at the Savannah River Site in South Carolina. This program investigated the subsurface conditions for the area known as ''Salt Disposition Facility (SDF), Site B'' located northeast of H-Area and within the S-Area. Data acquired from the Site B investigation includes both field exploration and laboratory test data

Automatic web site authoring with SiteGuide

NARCIS (Netherlands)

de Boer, V.; Hollink, V.; van Someren, M.W.; Kłopotek, M.A.; Przepiórkowski, A.; Wierzchoń, S.T.; Trojanowski, K.

2009-01-01

An important step in the design process for a web site is to determine which information is to be included and how the information should be organized on the web site’s pages. In this paper we describe ’SiteGuide’, a tool that automatically produces an information architecture for a web site that a

1726-IJBCS-Article-Mathias Pouya+

African Journals Online (AJOL)

hp

'Ouest (SOFITEX) du Burkina. Le choix des sites s'est fait de façon concertée avec les responsables des structures ... modes de fertilisation et d'itinéraires techniques préconisés par les ..... réaliser des investissements. Aussi, il possède.

IN-SITU BIOREMEDIATION OF CONTAMINATED GROUND WATER

Science.gov (United States)

This document is one in a series of Ground Water Issue papers which have been prepared in response to needs expressed by the Ground Water Forum. It is based on findings from the research community in concert with experience gained at sites undergoing remediation. the intent of th...

Estimation of emissions of nonmethane organic compounds from a closed landfill site using a landfill gas emission model

Energy Technology Data Exchange (ETDEWEB)

Nwachukwu, A.N. [Williamson Research Centre for Molecular Environmental Sciences, School of Earth, Atmospheric and Environmental Science, University of Manchester M13 9PL (United Kingdom); Diya, A.W. [Health Sciences Research Group, School of Medicine, University of Manchester M13 9PL (United Kingdom)

2013-07-01

Nonmethane organic compounds (NMOC) emissions from landfills often constitute significant risks both to human health and the general environment. To date very little work has been done on tracking the emissions of NMOC from landfills. To this end, a concerted effort was made to investigate the total annual mass emission rate of NMOC from a closed landfill site in South Manchester, United Kingdom. This was done by using field estimates of NMOC concentration and the landfill parameters into the Landfill Gas Emission Model embedded in ACTS and RISK software. Two results were obtained: (i) a deterministic outcome of 1.7218 x 10-7 kg/year, which was calculated from mean values of the field estimates of NMOC concentration and the landfill parameters, and (ii) a probabilistic outcome of 1.66 x 10-7 - 1.78 x 10-7 kg/year, which is a range of value obtained after Monte Carlo simulation of the uncertain parameters of the landfill including NMOC concentration. A comparison between these two results suggests that the probabilistic outcome is a more representative and reliable estimate of the total annual mass emission of NMOC especially given the variability of the parameters of the model. Moreover, a comparison of the model result and the safety standard of 5.0 x 10-5 kg/year indicate that the mass emission of NMOC from the studied landfill is significantly less than previously thought. However, given that this can accumulate to a dangerous level over a long period of time (such as the age of this landfill site); it may have started affecting the health of the people living within the vicinity of the landfill. A case is therefore made for more studies to be carried out on the emissions of other gases such as CH4 and CO2 from the studied landfill site, as this would help to understand the synergistic effect of the various gases being emitted from the landfill.

Urbanisme et prévention situationnelle : le cas de la dispute des professionnels à Lyon

Directory of Open Access Journals (Sweden)

Bilel Benbouzid

2010-12-01

Full Text Available Dans cet article, l’auteur s’interroge sur une dispute autour de la création d’une commission communale consultative de prévention situationnelle, dispositif expérimental mis en œuvre à Lyon pour expertiser les projets de sécurisation (lutte contre le crime des espaces urbains. En mobilisant la grille de la sociologie des épreuves, l’auteur analyse ce moment critique où les personnes en charge de l’urbanisme et celles responsables de la sécurité ont dû s’affronter et se mesurer autour de son acceptabilité et de sa définition. L’enjeu est de prendre au sérieux les logiques de justification des personnes afin d’analyser comment elles parviennent à trouver un accord. On voit que la prévention situationnelle apparaît comme un formidable catalyseur des débats autour du sens de la ville. En créant ce dispositif expérimental, la Ville de Lyon a produit sans en avoir l’intention, un espace de discussion et de cadrage de la controverse autour de la prévention situationnelle. Cette dernière apparaît comme le moyen pour les personnes en charge de la sécurité et de l’urbanisme de s’approprier un certain nombre de questions politiques et morales en mettant en avant la supériorité du politique sur la compétence technicienne.In this article, the author examines a dispute on the establishment of a municipal advisory committee on situational crime prevention, an experimental device implemented in Lyon to integrate safety in urban area planning. The author analyzes the critical moment when people in charge of planning and those of safety had to compete and measure themselves around its acceptability and its definition. The challenge is to take seriously the logic of justification of people in order to analyze how they find an agreement. We observe that situational crime prevention appears like a great catalyst of the debate about the meaning of the city. In creating this experimental instrument, the City of Lyon

Site description of Forsmark at completion of the site investigation phase. SDM-Site Forsmark

Energy Technology Data Exchange (ETDEWEB)

2008-12-15

The Swedish Nuclear Fuel and Waste Management Co., SKB, has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the model is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model for geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site, presents an integrated understanding of the Forsmark area at the completion of the surface-based investigations, which were conducted at Forsmark during the period 2002 to 2007. It also provides a summary of the abundant underlying data and the discipline-specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details in data analyses and modelling in the different disciplines. The Forsmark area is located in northern Uppland within the municipality of Oesthammar, about 120 km north of Stockholm. The candidate area for site investigation is located along the shoreline of Oeregrundsgrepen, within the north-western part of a major tectonic lens that formed between 1.87 and 1.85 billion years ago during the Svecokarelian orogeny. The candidate area is approximately 6 km long and 2 km wide. The

Site description of Laxemar at completion of the site investigation phase. SDM-Site Laxemar

Energy Technology Data Exchange (ETDEWEB)

2009-12-15

The Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the SDM is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model of geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site Laxemar, presents an integrated understanding of the Laxemar-Simpevarp area (with special emphasis on the Laxemar subarea) at the completion of the surface-based investigations, which were conducted during the period 2002 to 2007. A summary is also provided of the abundant underlying data and the discipline specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details of the data analyses and modelling of the different disciplines. The Laxemar-Simpevarp area is located in the province of Smaaland within the municipality of Oskarshamn, about 230 km south of Stockholm. The candidate area for site investigation is located along the shoreline of the strait of Kalmarsund, within a 1.8 billion year old suite of well preserved bedrock belonging to the Transscandinavian Igneous Belt formed during

Site description of Laxemar at completion of the site investigation phase. SDM-Site Laxemar

International Nuclear Information System (INIS)

2009-12-01

The Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the SDM is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model of geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site Laxemar, presents an integrated understanding of the Laxemar-Simpevarp area (with special emphasis on the Laxemar subarea) at the completion of the surface-based investigations, which were conducted during the period 2002 to 2007. A summary is also provided of the abundant underlying data and the discipline specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details of the data analyses and modelling of the different disciplines. The Laxemar-Simpevarp area is located in the province of Smaaland within the municipality of Oskarshamn, about 230 km south of Stockholm. The candidate area for site investigation is located along the shoreline of the strait of Kalmarsund, within a 1.8 billion year old suite of well preserved bedrock belonging to the Transscandinavian Igneous Belt formed during

Site description of Forsmark at completion of the site investigation phase. SDM-Site Forsmark

International Nuclear Information System (INIS)

2008-12-01

The Swedish Nuclear Fuel and Waste Management Co., SKB, has undertaken site characterisation in two different areas, Forsmark and Laxemar-Simpevarp, in order to identify a suitable location for a geological repository of spent nuclear fuel according to the KBS-3 method. The site investigations have been conducted in campaigns, punctuated by data freezes. After each data freeze, the site data have been analysed and modelling has been carried out with the overall purpose to develop a site descriptive model (SDM). The site descriptive model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It is also essential for safety assessment, since the model is the only source for site-specific input. Another important use of the site descriptive model is in the environmental impact assessment. An SDM is an integrated model for geology, thermal properties, rock mechanics, hydrogeology, hydrogeochemistry, bedrock transport properties and a description of the surface system. The site descriptive model compiled in the current report, SDM-Site, presents an integrated understanding of the Forsmark area at the completion of the surface-based investigations, which were conducted at Forsmark during the period 2002 to 2007. It also provides a summary of the abundant underlying data and the discipline-specific models that support the site understanding. The description relies heavily on background reports that address, in particular, details in data analyses and modelling in the different disciplines. The Forsmark area is located in northern Uppland within the municipality of Oesthammar, about 120 km north of Stockholm. The candidate area for site investigation is located along the shoreline of Oeregrundsgrepen, within the north-western part of a major tectonic lens that formed between 1.87 and 1.85 billion years ago during the Svecokarelian orogeny. The candidate area is approximately 6 km long and 2 km wide. The

On-site and off-site activities

International Nuclear Information System (INIS)

Martin, H.D.

1986-01-01

Design principles for NPP training programs. Effects of NPP contracts. Effects of domestic industrial activities. The role of international bodies. Requirements for on-site training. Training abroad, technical, financial and social aspects. Training center on-site, an evaluation. (orig.)

Region 9 NPL Sites (Superfund Sites 2013)

Science.gov (United States)

NPL site POINT locations for the US EPA Region 9. NPL (National Priorities List) sites are hazardous waste sites that are eligible for extensive long-term cleanup under the Superfund program. Eligibility is determined by a scoring method called Hazard Ranking System. Sites with high scores are listed on the NPL. The majority of the locations are derived from polygon centroids of digitized site boundaries. The remaining locations were generated from address geocoding and digitizing. Area covered by this data set include Arizona, California, Nevada, Hawaii, Guam, American Samoa, Northern Marianas and Trust Territories. Attributes include NPL status codes, NPL industry type codes and environmental indicators. Related table, NPL_Contaminants contains information about contaminated media types and chemicals. This is a one-to-many relate and can be related to the feature class using the relationship classes under the Feature Data Set ENVIRO_CONTAMINANT.

On-Site or Off-Site Renewable Energy Supply Options?

DEFF Research Database (Denmark)

Marszal, Anna Joanna; Heiselberg, Per; Jensen, Rasmus Lund

2012-01-01

The concept of a Net Zero Energy Building (Net ZEB) encompasses two options of supplying renewable energy, which can offset energy use of a building, in particular on-site or off-site renewable energy supply. Currently, the on-site options are much more popular than the off-site; however, taking...... into consideration the limited area of roof and/or façade, primarily in the dense city areas, the Danish weather conditions, the growing interest and number of wind turbine co-ops, the off-site renewable energy supply options could become a meaningful solution for reaching ‘zero’ energy goal in the Danish context...... five technologies, i.e., two on-site options: (1) photovoltaic, (2) micro combined heat and power, and three off-site options: (1) off-site windmill, (2) share of a windmill farm and (3) purchase of green energy from the 100% renewable utility grid. The results indicate that in case of the on...

The molecular mechanism of multi-ion conduction in K{sup +} channels

Energy Technology Data Exchange (ETDEWEB)

Gwan, J.F.

2007-01-19

Steered molecular dynamics (SMD) simulation method is applied to a fully solvated membrane-channel model for studying the ion permeation process in potassium channels. The channel model is based on the crystallographic structure of a prokaryotic K{sup +} channel- the KcsA channel, which is a representative of most known eukaryotic K{sup +} channels. It has long been proposed that the ion transportation in a conventional K{sup +}-channel follows a multi-ion fashion: permeating ions line in a queue in the channel pore and move in a single file through the channel. The conventional view of multi-ion transportation is that the electrostatic repulsion between ions helps to overcome the attraction between ions and the channel pore. In this study, we proposed two SMD simulation schemes, referred to 'the single-ion SMD' simulations and 'the multi-ion SMD' simulations. Concerted movements of a K-W-K sequence in the selectivity filter were observed in the single-ion SMD simulations. The analysis of the concerted movement reveals the molecular mechanism of the multi-ion transportation. It shows that, rather than the long range electrostatic interaction, the short range polar interaction is a more dominant factor in the multi-ion transportation. The polar groups which play a role in the concerted transportation are the water molecules and the backbone carbonyl groups of the selectivity filter. The polar interaction is sensitive to the relative orientation of the polar groups. By changing the orientation of a polar group, the interaction may switch from attractive to repulsive or vice versa. By this means, the energy barrier between binding sites in the selectivity filter can be switched on and off, and therefore the K{sup +} may be able to move to the neighboring binding site without an external driving force. The concerted transportation in the selectivity filter requires a delicate cooperation between K{sup +}, waters, and the backbone carbonyl groups. To

On Yi Concert "China' s memory, A Torch in the cloud"%浅谈《中国记忆·云中火把》彝族音乐会

Institute of Scientific and Technical Information of China (English)

张虎

2012-01-01

《中国记忆·云中火把》在上海音乐厅的成功演出，标志着楚雄彝族音乐走向世界的开始，音乐会的演出成功是楚雄、上海两地艺术家们交流、合作、共同努力的结果。以此为契机，努力打造更加优秀的音乐作品，来赢得人们对彝族音乐的认可。%The successful performance of "China' s memory, a torch in the cloud" in Shanghai concert hall marks the beginning of Yi music going global, to which the artists contribute through their communication, cooperation and joint effort. Taking this opportunity, we should create more good music works to win the world' s recognition.

Nuclear power plant site evaluation using site population-meterology factor

International Nuclear Information System (INIS)

Rho, B.H.; Kang, C.H.

1982-01-01

In this paper, as a site evaluation technique, SPNF(Site Population Neteorology Factor) which is modified from SPF(Site Population Factor) of the USNRC model, is defined from site population and meteorology data in order to consider the radiological impacts to the population at large from the atmospheric dispersion of the radioactive effluents released during routine plant operation as well as accidental conditions. The SPMF model proved its propriety from the comparison of SPMF and SPF for Kori site. The relative suitability of Korean sites to the U.S. sites have been also examined using SPF. (Author)

The heterothallic sugarbeet pathogen Cercospora beticola contains exon fragments of both MAT genes that are homogenized by concerted evolution.

Science.gov (United States)

Bolton, Melvin D; de Jonge, Ronnie; Inderbitzin, Patrik; Liu, Zhaohui; Birla, Keshav; Van de Peer, Yves; Subbarao, Krishna V; Thomma, Bart P H J; Secor, Gary A

2014-01-01

Dothideomycetes is one of the most ecologically diverse and economically important classes of fungi. Sexual reproduction in this group is governed by mating type (MAT) genes at the MAT1 locus. Self-sterile (heterothallic) species contain one of two genes at MAT1 (MAT1-1-1 or MAT1-2-1) and only isolates of opposite mating type are sexually compatible. In contrast, self-fertile (homothallic) species contain both MAT genes at MAT1. Knowledge of the reproductive capacities of plant pathogens are of particular interest because recombining populations tend to be more difficult to manage in agricultural settings. In this study, we sequenced MAT1 in the heterothallic Dothideomycete fungus Cercospora beticola to gain insight into the reproductive capabilities of this important plant pathogen. In addition to the expected MAT gene at MAT1, each isolate contained fragments of both MAT1-1-1 and MAT1-2-1 at ostensibly random loci across the genome. When MAT fragments from each locus were manually assembled, they reconstituted MAT1-1-1 and MAT1-2-1 exons with high identity, suggesting a retroposition event occurred in a homothallic ancestor in which both MAT genes were fused. The genome sequences of related taxa revealed that MAT gene fragment pattern of Cercospora zeae-maydis was analogous to C. beticola. In contrast, the genome of more distantly related Mycosphaerella graminicola did not contain MAT fragments. Although fragments occurred in syntenic regions of the C. beticola and C. zeae-maydis genomes, each MAT fragment was more closely related to the intact MAT gene of the same species. Taken together, these data suggest MAT genes fragmented after divergence of M. graminicola from the remaining taxa, and concerted evolution functioned to homogenize MAT fragments and MAT genes in each species. Published by Elsevier Inc.

Afrique Centrale

African Journals Online (AJOL)

PR BOKO

(Afrique Centrale) : peuplement de protozoaires ciliés et macro invertébrés ... Le lac d'Obili est un écosystème aquatique situé en plein cœur de Yaoundé en ...... électrique des eaux est assez stable, autour de 200 ; ce qui suppose que la ...

Superfund and Toxic Release Inventory Sites - MDC_ContaminatedSite

Data.gov (United States)

NSGIC Local Govt | GIS Inventory — A point feature class of open DERM Contaminated sites - see phase code for status of site. Contaminated sites identifies properties where environmental contamination...

Theoretical study on the reaction mechanism of hydrogenation of furfural to furfuryl alcohol on Lewis acidic BEA zeolites: effects of defect structure and tetravalent metals substitution.

Science.gov (United States)

Injongkol, Yuwanda; Maihom, Thana; Treesukul, Piti; Sirijaraensre, Jakkapan; Boekfa, Bundet; Limtrakul, Jumras

2017-09-13

Furfural acquired from agricultural sources is receiving extensive attention in the petrochemical industry as it offers an alternative route to generate more valuable hydrocarbon compounds. Herein, we investigate the furfural hydrogenation to furfuryl alcohol catalyzed by Lewis acidic BEA zeolites at the molecular level by means of the M06-L density functional theory. The mechanistic pictures in the catalytic procedure are revealed. The possible reaction pathways are considered to proceed via either concerted or stepwise mechanisms. With the contribution of zeolite oxygen bridging for the H-H splitting, the rate determining step activation barrier for the stepwise mechanism is 14.7 kcal mol -1 lower than that for the concerted mechanism. The stepwise reaction therefore seems to be favored compared to the concerted one. The catalytic effect of the defect zeolite framework on the stepwise mechanism is also investigated. The activation energy for the stepwise rate-determining step over this site is significantly lower than the corresponding step over the perfect one by 14.1 kcal mol -1 . Finally, the catalytic activity of tetravalent metal centers (Sn, Ge, Zr and Hf) substituted in BEA is also preliminarily compared and it is found to follow the order of Hf > Zr > Sn > Ge based on activation energies and the reaction rate. The difference in the activation energy can be traced back to the difference in the charge transfer from the catalytic site to the adsorbed molecules.

Two small RNAs, CrcY and CrcZ, act in concert to sequester the Crc global regulator in Pseudomonas putida, modulating catabolite repression.

Science.gov (United States)

Moreno, Renata; Fonseca, Pilar; Rojo, Fernando

2012-01-01

The Crc protein is a translational repressor that recognizes a specific target at some mRNAs, controlling catabolite repression and co-ordinating carbon metabolism in pseudomonads. In Pseudomonas aeruginosa, the levels of free Crc protein are controlled by CrcZ, a sRNA that sequesters Crc, acting as an antagonist. We show that, in Pseudomonas putida, the levels of free Crc are controlled by CrcZ and by a novel 368 nt sRNA named CrcY. CrcZ and CrcY, which contain six potential targets for Crc, were able to bind Crc specifically in vitro. The levels of CrcZ and CrcY were low under conditions generating a strong catabolite repression, and increased strongly when catabolite repression was absent. Deletion of either crcZ or crcY had no effect on catabolite repression, but the simultaneous absence of both sRNAs led to constitutive catabolite repression that compromised growth on some carbon sources. Overproduction of CrcZ or CrcY significantly reduced repression. We propose that CrcZ and CrcY act in concert, sequestering and modulating the levels of free Crc according to metabolic conditions. The CbrA/CbrB two-component system activated crcZ transcription, but had little effect on crcY. CrcY was detected in P. putida, Pseudomonas fluorescens and Pseudomonas syringae, but not in P. aeruginosa. © 2011 Blackwell Publishing Ltd.

Umatilla Satellite and Release Sites Project : Final Siting Report.

Energy Technology Data Exchange (ETDEWEB)

Montgomery, James M.

1992-04-01

This report presents the results of site analysis for the Umatilla Satellite and Release Sites Project. The purpose of this project is to provide engineering services for the siting and conceptual design of satellite and release facilities for the Umatilla Basin hatchery program. The Umatilla Basin hatchery program consists of artificial production facilities for salmon and steelhead to enhance production in the Umatilla River as defined in the Umatilla master plan approved in 1989 by the Northwest Power Planning Council. Facilities identified in the master plan include adult salmon broodstock holding and spawning facilities, facilities for recovery, acclimation, and/or extended rearing of salmon juveniles, and development of river sites for release of hatchery salmon and steelhead. The historic and current distribution of fall chinook, summer chinook, and coho salmon and steelhead trout was summarized for the Umatilla River basin. Current and future production and release objectives were reviewed. Twenty seven sites were evaluated for the potential and development of facilities. Engineering and environmental attributes of the sites were evaluated and compared to facility requirements for water and space. Site screening was conducted to identify the sites with the most potential for facility development. Alternative sites were selected for conceptual design of each facility type. A proposed program for adult holding facilities, final rearing/acclimation, and direct release facilities was developed.

Site decontamination

International Nuclear Information System (INIS)

Bicker, A.E.

1981-01-01

Among the several DOE sites that have been radiologically decontaminated under the auspices of the Nevada Operations Office are three whose physical characteristics are unique. These are the Tatum Dome Test Site (TDTS) near Hattiesburg, Mississippi; a location of mountainous terrain (Pahute Mesa) on the Nevada Test Site; and the GNOME site near Carlsbad, New Mexico. In each case the contamination, the terrain, and the climate conditions were different. This presentation includes a brief description of each site, the methods used to perform radiological surveys, the logistics required to support the decontamination (including health physics and sample analysis), and the specific techniques used to reduce or remove the contamination

Bedrock hydrogeology Forsmark. Site descriptive modelling, SDM-Site Forsmark

Energy Technology Data Exchange (ETDEWEB)

Follin, Sven (SF GeoLogic AB, Taeby (Sweden))

2008-12-15

The Swedish Nuclear Fuel and Waste Management Company (SKB) has conducted site investigations at two different locations, the Forsmark and Laxemar-Simpevarp areas, with the objective of siting a final repository for spent nuclear fuel according to the KBS-3 concept. Site characterisation should provide all data required for an integrated evaluation of the suitability of the investigated site and an important component in the characterisation work is the development of a hydrogeological model. The hydrogeological model is used by repository engineering to design the underground facility and to develop a repository layout adapted to the site. It also provides input to the safety assessment. Another important use of the hydrogeological model is in the environmental impact assessment. This report presents the understanding of the hydrogeological conditions of the bedrock at Forsmark reached following the completion of the surface-based investigations and provides a summary of the bedrock hydrogeological model and the underlying data supporting its development. It constitutes the main reference on bedrock hydrogeology for the site descriptive model concluding the surface-based investigations at Forsmark, SDM-site, and is intended to describe the hydraulic properties and hydrogeological conditions of the bedrock at the site and to give the information essential for demonstrating understanding

Study methods for the drillings around the underground nuclear explosions in the Sahara. Part 1. study of rock samples; Methodes d'etude des forages realises autour des explosions nucleaires souterraines au Sahara. Premiere partie: etude des echantillons de roche

Energy Technology Data Exchange (ETDEWEB)

Derlich, S [Commissariat a l' Energie Atomique, Bruyers-le-Chatel (France). Centre d' Etudes

1969-07-01

An examination of the mechanical effects produced on rocks by an underground nuclear explosion calls for the use of particular means of exploration which are described in this report, special attention being paid to the equipment used in connection with the French nuclear tests in the Sahara. The drilling methods used (rotary and turbo-drilling) are adapted to the particular conditions of the sampling programme, to the radioactivity and to the temperature in the region of the explosion. A study of the samples makes it possible to obtain the new characteristics of the rock and to assess the chemical and mechanical transformations which it has undergone. An examination of the core obtained from the drilling, together with a knowledge of the drilling parameters (depth of the probe, sample recovery, etc...), makes it possible to study the extent and the characteristics of the zones which have been damaged to different degrees according to their distance from the zero point: cavity, strongly powdered zone, fractured zone, chimney, zones containing high stresses leading to a particular type of fracture of the cores. The problems connected with the interpretation of the results are also presented. (author) [French] L'examen des effets mecaniques provoques par une explosion nucleaire souterraine sur la roche necessite la mise en oeuvre de moyens d'exploration particuliers dont l'expose fait l'objet de ce rapport, essentiellement pour les moyens utilises autour des essais nucleaires francais au Sahara. Les methodes de forage (rotary et turboforage) sont adaptees aux conditions particulieres dues au programme d'echantillonnage, a la radioactivite et a la temperature regnant a proximite du point de tir. L'etude des echantillons permet la determination des nouveaux caracteres de la roche et de ses transformations chimique et mecanique. L'examen des carottes et l'utilisation des parametres de forage (cotes sondeurs, recuperation des echantillons, etc...) permettent d'etudier l

Social Media Sites

Science.gov (United States)

Media Sites Site Registration Contact Us Search AF.mil: Home > AF Sites > Social Media Sites Social Media Welcome to the Air Force social media directory! The directory is a one-stop shop of official Air Force social media pages across various social media sites. Social media is all about

South of Sahara | Page 46 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

South of Sahara. Sud du Sahara. Read more about Open Architecture, Standards and Information Systems (OASIS) for Healthcare in Africa. Language English. Read more about Gestion intégrée de l'eau, de l'assainissement et des déchets solides dans de petits centres urbains autour du lac Victoria (Kenya). Language ...

2579-IJBCS-Article-Marietou Tendeng

African Journals Online (AJOL)

hp

9 janv. 2013 ... Dynamique de la mangrove du marigot de Bignona autour du barrage d'Affiniam ..... géométriques a été complétée par un contrôle visuel effectué par la ..... la gestion du barrage, de les responsabiliser et de les suivre jusqu'à ...

Objets d'art, oeuvres d'art

Directory of Open Access Journals (Sweden)

Muriel Verbeeck-Boutin

2008-10-01

Full Text Available Il s’agit d’aborder ici les imprécisions de la langue française, autour des notions d’œuvre, d’art, d’objet. Sans préciser les concepts, il est impossible de s’entendre. La solution tient peut-être à un emprunt au vocabulaire d’outre-Atlantique.

TBT recommends : Nomme jazz spring concert. Easter celebration. Hakan Rosengren in concert

Index Scriptorium Estoniae

2006-01-01

Inglise jazzlaulja Claire Fosteri ja trompetisti Paul Jayasinha kontserdist 8. apr. Nõmme kultuurimajas Tallinnas. Kontsertidest 16. ja 17. apr. Läti Etnograafiamuuseumis ning Usma kirikus. Rootsi klarnetisti Hakan Rosengreni ja Leedu Rahvusliku Sümfooniaorkestri kontserdist Leedu Rahvusliku Filharmoonia Hallis Vilniuses

Site operations

International Nuclear Information System (INIS)

House, W.B.; Ebenhack, D.G.

1989-01-01

This chapter is a discussion of the management and operations practices used at the Barnwell Waste Management Facility in Barnwell, SC. The following topics are discussed: (1) Waste receiving and inspection, including manifest and certificates of compliance, radiological surveys, disposition of nonconforming items, and decontamination and disposition of secondary waste streams; (2) Waste disposal, including Title 10 CFR 61 requirements, disposal area evaluations, shipment offloading, container emplacement, and radiation protection; (3) Trench closure, including trench backfilling, trench capping, and permanent markers; (4) Site maintenance and stabilization, including trench maintenance, surface water management, and site closure activities; (5) Site monitoring programs, including operational monitoring, and environmental monitoring program; (6) Personnel training and qualifications, including basic training program, safety training program, special skills training, and physical qualifications; (7) Records management, including waste records, personnel training records, personnel dosimetry records, site monitoring records, trench qualification and construction records, and site drawings and stabilization records; (8) Site security; (9) Emergency response plans; and (10) Quality assurance

Westinghouse Savannah River Site vendor forum: An innovative cooperative technology development success

International Nuclear Information System (INIS)

Sturm, H.F. Jr.

1996-01-01

The Westinghouse Savannah River Company (WSRC) Supplier Environmental and Waste Management Information Exchange Forum was held August 31 - September 1, 1993. The forum, which was planned and conducted in concert with the Department of Energy Savannah River Operations Office (DOE-SROO), was held to foster a technical exchange in which new, innovative technologies were proposed by suppliers, to identify more cost-effective methods to apply to future and on-going activities, to increase use of the private sector, and to promote partnerships with other industries. The two day forum provided the opportunity for WSRC and DOE-SR to review program activities and challenges in five major areas, Savannah River Technology Center, Solid Waste Facilities, Environmental Restoration, Environmental Monitoring, and Decontamination and Decommissioning through formal presentations. The second day was designed to provide suppliers the opportunity to talk about current and future activities and challenges with representatives of each of these areas at display booths, special high interest topic interactive sessions, and site tours. Each attendee was then invited to submit pre-proposals relative to the abstracts presented in The Special Consolidate Solicitation for Environmental and Waste Management Basic and Applied Research and Research-Related Development and/or Demonstration No. E10600-E1 document. Twenty-five contracts totaling $12 million were awarded. Twenty-four contracts have now been completed. This paper provides an overview of the pre forum activities, the forum, post-forum and proposal review process, and most importantly a description of the technologies demonstrated, the benefits and savings derived, and future use potential from a DOE perspective, as well as technology transfer and industrial partnership potential

INTERFON

CERN Multimedia

Interfon

2013-01-01

www.interfon.fr Rendez-vous sur notre site pour toutes les « News » Interfon Journée Portes ouvertes Le mercredi 9 octobre 2013 dès 16h00 Salle Jean Monnet à Saint-Genis-Pouilly Rencontrez nos partenaires Venez nous rejoindre et découvrir nos fournisseurs partenaires autour d’un buffet campagnard Commandez votre fioul au tarif spécial « Portes ouvertes » Dégustez et commandez notre sélection de vins et champagnes «Tarifs préférentiels» Nouveau partenaire Visages du Monde 31, Quai du Mont-Blanc 1211 – CH Genève Tél : 41 22 731 26 34 www.vdmtravel.ch Voyagez autrement ! Voyage sur brochure ou sur mesure Sur simple présentation de votre carte de sociétaire, vous bénéficiez d’une remise de 2 % sur les produits brochures de nos partenaires : AD...

Interfon

CERN Multimedia

Interfon

2013-01-01

www.interfon.fr Rendez-vous sur notre site pour toutes les « News » Interfon « News » « Nouveau partenaire chez Interfon » L’équipe de vente de la Direction des Opérations Internationales de Peugeot et Citroën vous accueillera le 13 juin de 10 h à 18 h à l’Holiday Inn de Thoiry autour d’un buffet Pour vous faire découvrir et essayer  les dernières nouveautés  Peugeot 2008 et 208 GTi, nouveau Citroën C4 Picasso... Présentez votre carte de sociétaire et profitez des conditions de vente préférentielles réservées aux fonctionnaires internationaux. Vos contacts Yves Moreau :   +33 (0)6 30 52 83 11 yves.moreau@mpsa.com Claude Paronneau :  +33 (0) 6  75 76 91 04 claude.paronneau@mpsa.com * * * * * Les 13, 1...

Confidence assessment. Site-descriptive modelling SDM-Site Laxemar

International Nuclear Information System (INIS)

2009-06-01

The objective of this report is to assess the confidence that can be placed in the Laxemar site descriptive model, based on the information available at the conclusion of the surface-based investigations (SDM-Site Laxemar). In this exploration, an overriding question is whether remaining uncertainties are significant for repository engineering design or long-term safety assessment and could successfully be further reduced by more surface-based investigations or more usefully by explorations underground made during construction of the repository. Procedures for this assessment have been progressively refined during the course of the site descriptive modelling, and applied to all previous versions of the Forsmark and Laxemar site descriptive models. They include assessment of whether all relevant data have been considered and understood, identification of the main uncertainties and their causes, possible alternative models and their handling, and consistency between disciplines. The assessment then forms the basis for an overall confidence statement. The confidence in the Laxemar site descriptive model, based on the data available at the conclusion of the surface based site investigations, has been assessed by exploring: - Confidence in the site characterization data base, - remaining issues and their handling, - handling of alternatives, - consistency between disciplines and - main reasons for confidence and lack of confidence in the model. Generally, the site investigation database is of high quality, as assured by the quality procedures applied. It is judged that the Laxemar site descriptive model has an overall high level of confidence. Because of the relatively robust geological model that describes the site, the overall confidence in the Laxemar Site Descriptive model is judged to be high, even though details of the spatial variability remain unknown. The overall reason for this confidence is the wide spatial distribution of the data and the consistency between

Confidence assessment. Site-descriptive modelling SDM-Site Laxemar

Energy Technology Data Exchange (ETDEWEB)

2008-12-15

The objective of this report is to assess the confidence that can be placed in the Laxemar site descriptive model, based on the information available at the conclusion of the surface-based investigations (SDM-Site Laxemar). In this exploration, an overriding question is whether remaining uncertainties are significant for repository engineering design or long-term safety assessment and could successfully be further reduced by more surface-based investigations or more usefully by explorations underground made during construction of the repository. Procedures for this assessment have been progressively refined during the course of the site descriptive modelling, and applied to all previous versions of the Forsmark and Laxemar site descriptive models. They include assessment of whether all relevant data have been considered and understood, identification of the main uncertainties and their causes, possible alternative models and their handling, and consistency between disciplines. The assessment then forms the basis for an overall confidence statement. The confidence in the Laxemar site descriptive model, based on the data available at the conclusion of the surface based site investigations, has been assessed by exploring: - Confidence in the site characterization data base, - remaining issues and their handling, - handling of alternatives, - consistency between disciplines and - main reasons for confidence and lack of confidence in the model. Generally, the site investigation database is of high quality, as assured by the quality procedures applied. It is judged that the Laxemar site descriptive model has an overall high level of confidence. Because of the relatively robust geological model that describes the site, the overall confidence in the Laxemar Site Descriptive model is judged to be high, even though details of the spatial variability remain unknown. The overall reason for this confidence is the wide spatial distribution of the data and the consistency between

Crystallographic and molecular dynamics analysis of loop motions unmasking the peptidoglycan-binding site in stator protein MotB of flagellar motor.

Directory of Open Access Journals (Sweden)

Cyril F Reboul

Full Text Available BACKGROUND: The C-terminal domain of MotB (MotB-C shows high sequence similarity to outer membrane protein A and related peptidoglycan (PG-binding proteins. It is believed to anchor the power-generating MotA/MotB stator unit of the bacterial flagellar motor to the peptidoglycan layer of the cell wall. We previously reported the first crystal structure of this domain and made a puzzling observation that all conserved residues that are thought to be essential for PG recognition are buried and inaccessible in the crystal structure. In this study, we tested a hypothesis that peptidoglycan binding is preceded by, or accompanied by, some structural reorganization that exposes the key conserved residues. METHODOLOGY/PRINCIPAL FINDINGS: We determined the structure of a new crystalline form (Form B of Helicobacter pylori MotB-C. Comparisons with the existing Form A revealed conformational variations in the petal-like loops around the carbohydrate binding site near one end of the β-sheet. These variations are thought to reflect natural flexibility at this site required for insertion into the peptidoglycan mesh. In order to understand the nature of this flexibility we have performed molecular dynamics simulations of the MotB-C dimer. The results are consistent with the crystallographic data and provide evidence that the three loops move in a concerted fashion, exposing conserved MotB residues that have previously been implicated in binding of the peptide moiety of peptidoglycan. CONCLUSION/SIGNIFICANCE: Our structural analysis provides a new insight into the mechanism by which MotB inserts into the peptidoglycan mesh, thus anchoring the power-generating complex to the cell wall.

Siting guidelines and their role in repository site selection

International Nuclear Information System (INIS)

Hanlon, C.L.

1985-01-01

The first requirement of the Nuclear Waste Policy Act was for the Secretary of Energy to issue general guidelines for siting repositories. The guidelines were to specify detailed geologic considerations that would be the primary criteria for the selection of sites in various host rocks, as well as factors that would qualify or disqualify any site from development as a repository. These guidelines were clearly intended to provide not only the framework for the siting program but also the stimulus for establishing effective communication and consultation among the parties involved in the program. The Act further required that the guidelines be a factor in the development of all future decision documents of the Office of Civilian Radioactive Waste Management, including the environmental assessments that would accompany the nomination of sites for characterization, the site-characterization plans that are to be prepared before the sinking of exploratory shafts at any candidate site, and the environmental impact statement that is to support the recommendation of a site for development as a repository. More than two years after its passage, the intention of the Act for the guidelines has been realized. Concurred in by the Nuclear Regulatory Commission on June 22, 1984, and issued by the Department in November 1984, the guidelines include postclosure technical guidelines that apply to conditions governing the long-term performance of the repository system; preclosure technical guidelines that apply to conditions governing the siting, construction, operation, and closure of the repository; and system guidelines whose objective is to ensure that the regulatory requirements of the Environmental Protection Agency and the Nuclear Regulatory Commission are met

SiteGuide: An example-based approach to web site development assistance

NARCIS (Netherlands)

Hollink, V.; de Boer, V.; van Someren, M.; Filipe, J.; Cordeiro, J.

2009-01-01

We present ‘SiteGuide’, a tool that helps web designers to decide which information will be included in a new web site and how the information will be organized. SiteGuide takes as input URLs of web sites from the same domain as the site the user wants to create. It automatically searches the pages

Professionnalisation de l'agriculture : Une alternative aux effets des ...

African Journals Online (AJOL)

La démarche méthodologique utilisée s'articule autour de la recherche documentaire et de la collecte des informations socio-économiques détaillées obtenues auprès des ménages sur les organisations professionnelles agricoles et sur le processus de professionnalisation de l'agriculture. Un diagnostic agroclimatique a ...

Case report

African Journals Online (AJOL)

abp

22 janv. 2013 ... Abstract. Le volvulus gastrique est une rotation anormale de l'estomac autour de son axe. La forme aiguë constitue une urgence chirurgicale. Le diagnostic est souvent retardé en raison d'une symptomatologie fréquemment non spécifique. Des signes respiratoires tels la dyspnée et le hoquet peuvent.

Travaux Neuchatelois de linguistique (Neuchatel Working Papers in Linguistics).

Science.gov (United States)

Neuchatel Univ. (Switzerland). Inst. de Linguistique.

This collection of working papers in linguistics includes four works. "Autour de la racine indo-europeenne 'pet-' ('voler') (pour servir a l'histoire des faits latins)" ("Concerning the Indo-European Root 'Pet-' ('To Fly') (To Serve as an Example of Latin Facts)" by Claude Sandoz looks at the Latin manifestations of the root and illustrates the…

Dynamique de croissance et taux de mortalité de Rhizophora spp ...

African Journals Online (AJOL)

SARAH

30 janv. 2015 ... Dynamique des paysages végétaux du littoral centre-ouest du Gabon autour de. Port-Gentil : Approche spatiale et analyse des données de terrain. Thèse de doctorat. Univ. Paul-Valery Montpellier 3, France. 302 p. Spalding MD, Blasco F, Field CD, 1997. World. Mangrove Atlas. ISME, Okinawa, Japan. 251.

Author Details

African Journals Online (AJOL)

Aouta, Alain. Vol 10, No 2 (2016) - Articles Dynamique de la mangrove du marigot de Bignona autour du barrage d'Affiniam (Casamance, Sénégal) Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

Author Details

African Journals Online (AJOL)

Ayissi, I. Vol 7, No 5 (2013) - Articles Caractérisation des habitats benthiques et ponte des tortues marines autour du parc national de Campo-Ma'an (Cameroun) Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

coloproctectomie avec anastomose colo-sus-anale pour tumeur ...

African Journals Online (AJOL)

Une coloproctectomie fut réalisée le 30/06/2014 avec anastomose colo-anale, colostomie de protection sous-couvert d'une transfusion sanguine. L'examen histologique du segment colorectal prélevé objectiva une rectocolite granulomateuse autour de nombreux oeufs de schistosomes. En effet, le patient a vécu à Pahou, ...

Physiopathologie et Pathologie des Affections du Rachis en Medecine Aerospatiale (Physiopathology and Pathology of Affections of the Spine in Aerospace Medicine),

Science.gov (United States)

1981-04-01

blassuras en r6sultant. R.G. SNYDER (230) observe que 90 individus survivant aprbs des chutes libres variant entre 30 et 274 m~tres, 9 sont vivants apr~a...ea. Cette affection touchant i’homme jeune, n’a pas une r6partition gdographinue uniforme. Elle intdrease particui~rement ins sujets vivant autour du

Moundir LASSASSI Nacer-Eddine HAMMOUDA

African Journals Online (AJOL)

économique. Cette évidente proximité permet de situer les travaux sur les entreprises familiales à la lumière des recherches sur l‟entrepre- neuriat. Reste que les ... supporte aucune charge sociale, contribue à l‟accroissement de la compétitivité ... Le destin solidaire de survie autour d‟un patrimoine unique contribue à ...

Feedback from performance assessment to site characterisation. The SITE-94 example

International Nuclear Information System (INIS)

Dverstorp, B.; Geier, J.

1999-01-01

Interaction and information exchange between site characterisation and performance assessment are key features of any successful radioactive waste management programme. Some examples are presented of the types of feedback that can be offered from performance assessment to site characterisation, based on SKI's most recent performance assessment project, SITE-94. SITE-94 in Sweden was an assessment of a hypothetical repository for spent nuclear fuel, based on real data gathered in the surface-based investigation of the Aespoe Hard Rock Laboratory site. Examples of feedback are given concerning quality control of data and site investigation procedures, identification of key parameters for the performance assessment, use of models for planning and evaluation of a site investigation, data sampling strategies, and guidance on future priorities for further development of site investigation methods. Because site characterisation serves multiple purposes, including provision of data for repository design and construction, it must account for and compromise among requirements from several lines of analyses in the performance assessment. (author)

The GDP-switched GAF domain of DcpA modulates the concerted synthesis/hydrolysis of c-di-GMP in Mycobacterium smegmatis.

Science.gov (United States)

Chen, Hui-Jie; Li, Na; Luo, Ye; Jiang, Yong-Liang; Zhou, Cong-Zhao; Chen, Yuxing; Li, Qiong

2018-04-09

The second messenger c-di-GMP [bis-(3'-5')-cyclic dimeric guanosine monophosphate] plays a key role in bacterial growth, survival and pathogenesis, and thus its intracellular homeostasis should be finely maintained. Mycobacterium smegmatis encodes a GAF (mammalian c G MP-regulated phosphodiesterases, Anabaena a denylyl cyclases and Escherichia coli transcription activator F hlA) domain containing bifunctional enzyme DcpA ( d iguanylate c yclase and p hosphodiesterase A ) that catalyzes the synthesis and hydrolysis of c-di-GMP . Here, we found that M. smegmatis DcpA catalyzes the hydrolysis of c-di-GMP at a higher velocity, compared with synthetic activity, resulting in a sum reaction from the ultimate substrate GTP to the final product pGpG [5'-phosphoguanylyl-(3'-5')-guanosine]. Fusion with the N-terminal GAF domain enables the GGDEF (Gly-Gly-Asp-Glu-Phe) domain of DcpA to dimerize and accordingly gain synthetic activity. Screening of putative metabolites revealed that GDP is the ligand of the GAF domain. Binding of GDP to the GAF domain down-regulates synthetic activity, but up-regulates hydrolytic activity, which, in consequence, might enable a timely response to the transient accumulation of c-di-GMP at the stationary phase or under stresses. Combined with the crystal structure of the EAL (Glu-Ala-Leu) domain and the small-angle X-ray scattering data, we propose a putative regulatory model of the GAF domain finely tuned by the intracellular GTP/GDP ratio. These findings help us to better understand the concerted control of the synthesis and hydrolysis of c-di-GMP in M. smegmatis in various microenvironments. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles

Directory of Open Access Journals (Sweden)

Leon J. Schurgers

2018-04-01

Full Text Available The ageing population continues to suffer from its primary killer, cardiovascular disease (CVD. Despite recent advances in interventional medicinal and surgical therapies towards the end of the 20th century, the epidemic of cardiovascular disease has not been halted. Yet, rather than receding globally, the burden of CVD has risen to become a top cause of morbidity and mortality worldwide. Most CVD arises from thrombotic rupture of an atherosclerotic plaque, the pathologic thickening of coronary and carotid artery segments and subsequent distal ischemia in heart or brain. In fact, one-fifth of deaths are directly attributable to thrombotic rupture of a vulnerable plaque. Atherosclerotic lesion formation is caused by a concert of interactions between circulating leukocytes and platelets, interacting with the endothelial barrier, signalling into the arterial wall by the release of cytokines and extracellular vesicles (EVs. Both platelet- and cell-derived EVs represent a novel mechanism of cellular communication, particularly by the transport and transfer of cargo and by reprogramming of the recipient cell. These interactions result in phenotypic switching of vascular smooth muscle cells (VSMCs causing migration and proliferation, and subsequent secretion of EVs. Loss of VSMCs attracts perivascular Mesenchymal Stem Cells (MSCs from the adventitia, which are a source of VSMCs and contribute to repair after vascular injury. However, continuous stress stimuli eventually switch phenotype of cells into osteochondrogenic VSMCs facilitating vascular calcification. Although Virchow’s triad is over 100 years old, it is a reality that is accurate today. It can be briefly summarised as changes in the composition of blood (platelet EVs, alterations in the vessel wall (VSMC phenotypic switching, MSC infiltration and EV release and disruption of blood flow (atherothrombosis. In this paper, we review the latest relevant advances in the identification of

Concerted actions of insulin-like growth factor 1, testosterone, and estradiol on peripubertal bone growth: a 7-year longitudinal study.

Science.gov (United States)

Xu, Leiting; Wang, Qin; Wang, Qingju; Lyytikäinen, Arja; Mikkola, Tuija; Völgyi, Eszter; Cheng, Shumei; Wiklund, Petri; Munukka, Eveliina; Nicholson, Patrick; Alén, Markku; Cheng, Sulin

2011-09-01

A better understanding of how bone growth is regulated during peripuberty is important for optimizing the attainment of peak bone mass and for the prevention of osteoporosis in later life. In this report we used hierarchical models to evaluate the associations of insulin-like growth factor 1 (IGF-1), estradiol (E(2) ), and testosterone (T) with peripubertal bone growth in a 7-year longitudinal study. Two-hundred and fifty-eight healthy girls were assessed at baseline (mean age 11.2 years) and at 1, 2, 3.5, and 7 years. Serum concentrations of IGF-1, E(2) , and T were determined. Musculoskeletal properties in the left lower leg were measured using peripheral quantitative computed tomography (pQCT). Serum levels of IGF-1, E(2) , and T increased dramatically before menarche, whereas they decreased, plateaued, or increased at a lower rate, respectively, after menarche. IGF-1 level was positively associated with periosteal circumference (PC) and total bone mineral content (tBMC) throughout peripuberty but not after adjustment for muscle cross-sectional area (mCSA). On the other hand, IGF-1 was associated with tibial length (TL) independently of mCSA before menarche. T was positively associated with TL, PC, tBMC, and cortical volumetric bone mineral density, independent of mCSA, before menarche but not after. E(2) was associated with TL positively before menarche but negatively after menarche. These findings suggest that during puberty, circulating IGF-1 promotes bone periosteal apposition and mass accrual indirectly, probably through stimulating muscle growth, whereas the effects of sex steroids on bone growth differ before and after menarche, presenting a biphasic pattern. Hence the concerted actions of these hormones are essential for optimal bone development in peripuberty. Copyright © 2011 American Society for Bone and Mineral Research.

Site characterization plan:

International Nuclear Information System (INIS)

1988-01-01

The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed

to view fulltext PDF

Indian Academy of Sciences (India)

2013-07-10

Jul 10, 2013 ... then released from the transcription site and gradually move to .... 5′-cap structure by the concerted action of Dcp1p/Dcp2p (called decapping complex) ... involves the mitotic exit network (MEN) kinase Dbf2p and its interacting partner ...... and Upf3p, which in turn promotes the decapping reaction mediated ...

INFLAMMATORY BOWEL DISEASE IN HISPANIC COMMUNITIES: a concerted South American approach could identify the aetiology of Crohn’s disease and ulcerative colitis

Directory of Open Access Journals (Sweden)

Affifa FARRUKH

2014-12-01

Full Text Available Despite intensive research we remain ignorant of the cause of both Crohn’s disease and ulcerative colitis. The dramatic rise in incidence, particularly of Crohn’s disease, points towards environmental factors as playing a significant role. A major purpose of this review is to stimulate a co-ordinated international effort to establish an on-going data base in Central and South America in which new cases are registered and through which investigations into aetiology can be conducted. In both Brazil and Mexico there is evidence that the incidence of ulcerative colitis is increasing, as also is the case for Crohn’s disease in Brazil. The pattern of disease is, therefore, directly comparable to that reported from Europe and the USA during the 1970s and 1980s, but much lower than contemporary data from Spain. Although the incidence is similar to that reported from Portugal, the studies from Almada and Braga were conducted a decade before that from Sao Paulo. The situation in Brazil compares dramatically with Uruguay and Argentina where the reported incidence of inflammatory bowel disease is significantly less. However, with growing industrialisation it is likely that there will be an explosion of inflammatory bowel disease in some areas of Central and South America over the next 20 years. The creation of a network of researchers across South and Central America is a real possibility and through a Concerted Action there is the possibility that major strides could be made towards understanding the cause of inflammatory bowel disease and so develop preventive strategies.

SiteFind: A software tool for introducing a restriction site as a marker for successful site-directed mutagenesis

Directory of Open Access Journals (Sweden)

Evans Paul M

2005-12-01

Full Text Available Abstract Background Site-directed mutagenesis is a widely-used technique for introducing mutations into a particular DNA sequence, often with the goal of creating a point mutation in the corresponding amino acid sequence but otherwise leaving the overall sequence undisturbed. However, this method provides no means for verifying its success other than sequencing the putative mutant construct: This can quickly become an expensive method for screening for successful mutations. An alternative to sequencing is to simultaneously introduce a restriction site near the point mutation in manner such that the restriction site has no effect on the translated amino acid sequence. Thus, the novel restriction site can be used as a marker for successful mutation which can be quickly and easily assessed. However, finding a restriction site that does not disturb the corresponding amino acid sequence is a time-consuming task even for experienced researchers. A fast and easy to use computer program is needed for this task. Results We wrote a computer program, called SiteFind, to help us design a restriction site within the mutation primers without changing the peptide sequence. Because of the redundancy of genetic code, a given peptide can be encoded by many different DNA sequences. Since the list of possible restriction sites for a given DNA sequence is not always obvious, SiteFind automates this task. The number of possible sequences a computer program must search through increases exponentially as the sequence length increases. SiteFind uses a novel "moving window" algorithm to reduce the number of possible sequences to be searched to a manageable level. The user enters a nucleotide sequence, specifies what amino acid residues should be changed in the mutation, and SiteFind generates a list of possible restriction sites and what nucleotides must be changed to introduce that site. As a demonstration of its use, we successfully generated a single point mutation

Remaining Sites Verification Package for the 128-B-3 Burn Pit Site, Waste Site Reclassification Form 2006-058

Energy Technology Data Exchange (ETDEWEB)

L. M. Dittmer

2006-11-17

The 128-B-3 waste site is a former burn and disposal site for the 100-B/C Area, located adjacent to the Columbia River. The 128-B-3 waste site has been remediated to meet the remedial action objectives specified in the Remaining Sites ROD. The results of verification sampling demonstrated that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results of sampling at upland areas of the site also showed that residual contaminant concentrations are protective of groundwater and the Columbia River.

Site characterization plan:

International Nuclear Information System (INIS)

1988-01-01

The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in acordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and eveloping a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing prinicples, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed. 880 refs., 130 figs., 25 tabs

On multi-site damage identification using single-site training data

Science.gov (United States)

Barthorpe, R. J.; Manson, G.; Worden, K.

2017-11-01

This paper proposes a methodology for developing multi-site damage location systems for engineering structures that can be trained using single-site damaged state data only. The methodology involves training a sequence of binary classifiers based upon single-site damage data and combining the developed classifiers into a robust multi-class damage locator. In this way, the multi-site damage identification problem may be decomposed into a sequence of binary decisions. In this paper Support Vector Classifiers are adopted as the means of making these binary decisions. The proposed methodology represents an advancement on the state of the art in the field of multi-site damage identification which require either: (1) full damaged state data from single- and multi-site damage cases or (2) the development of a physics-based model to make multi-site model predictions. The potential benefit of the proposed methodology is that a significantly reduced number of recorded damage states may be required in order to train a multi-site damage locator without recourse to physics-based model predictions. In this paper it is first demonstrated that Support Vector Classification represents an appropriate approach to the multi-site damage location problem, with methods for combining binary classifiers discussed. Next, the proposed methodology is demonstrated and evaluated through application to a real engineering structure - a Piper Tomahawk trainer aircraft wing - with its performance compared to classifiers trained using the full damaged-state dataset.

Nevada Test Site Environmental Report 2005, Attachment A - Site Description

International Nuclear Information System (INIS)

Cathy A. Wills

2006-01-01

This appendix to the ''Nevada Test Site Environmental Report 2005'', dated October 2006 (DOE/NV/11718--1214; DOE/NV/25946--007) expands on the general description of the Nevada Test Site (NTS) presented in the Introduction. Included are subsections that summarize the site?s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site which afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This appendix complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report

Nevada Test Site Environmental Report 2005, Attachment A - Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy A. Wills

2006-10-01

This appendix to the ''Nevada Test Site Environmental Report 2005'', dated October 2006 (DOE/NV/11718--1214; DOE/NV/25946--007) expands on the general description of the Nevada Test Site (NTS) presented in the Introduction. Included are subsections that summarize the site?s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site which afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This appendix complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Siting Practices and Site Licensing Process for New Reactors in Canada

International Nuclear Information System (INIS)

Vos, Marcel de

2011-01-01

'Siting' in Canada is composed of Site Evaluation and Site Selection. As outlined in CNSC Regulatory Document RD-346 Site Evaluation for New Nuclear Power Plants (based on IAEA NS-R-3), prior to the triggering of the Environmental Assessment (EA) and licensing processes, the proponent is expected to use a robust process to characterize proposed sites over the full life cycle of the facility, and then develop a fully documented defense of the site selection case. This case forms the backbone for submissions in support of the EA and the application for a License to Prepare Site which will be reviewed by the CNSC and other applicable federal authorities. The Environmental Assessment process and License to Prepare Site in Canada do not require a proponent to select a specific design; however, CNSC does not accept a 'black box' approach to siting. CNSC balances the level of design information required with the extent of safety assurance desired for any designs being contemplated for the proposed site. Nevertheless, the design information submitted must be sufficient to justify the site as suitable for all future licensing stages. The depth of plant design information contributes significantly to the credibility of the applicant's case for both the EA and application for License to Prepare Site. The review process utilizes an assessment plan with defined review stages and timelines. The outcome of these reviews is a series of recommendations to a federal government appointed Joint Review Panel (which also serves as a panel of the 'Commission') which, following public hearings, renders a decision regarding the EA, and subsequently, the application for a License to Prepare Site. (author)

SITE-94. Site specific base data for the performance assessment

International Nuclear Information System (INIS)

Geier, J.; Tiren, S.; Dverstorp, B.; Glynn, P.

1996-06-01

This report documents the site specific base data that were available, and the utilization of these data within SITE-94. A brief summary is given of SKB's preliminary site investigations for the Aespoe Hard Rock Laboratory (HRL), which were the main source of site-specific data for SITE-94, and an overview is given of the field methods and instrumentation for the preliminary investigations. A compilation is given of comments concerning the availability and quality of the data for Aespoe, and specific recommendations are given for future site investigations. It was found that the HRL pre-investigations produced a large quantity of data which were, for the most part, of sufficient quality to be valuable for a performance assessment. However, some problems were encountered regarding documentation, procedural consistency, positional information, and storage of the data from the measurements. 77 refs, 4 tabs

Quantifying siting difficulty: a case study of US transmission line siting

Energy Technology Data Exchange (ETDEWEB)

Vajjhala, S.P. [Resources for the Future, Washington DC (United States); Fischbeck, P.S. [Carnegie Mellon University, Pittsburgh, PA (United States). Departments of Social and Decision Sciences and Engineering and Public Policy

2007-01-15

The worldwide demand for new energy infrastructures has been paralleled in recent years by the increasing difficulty of siting major facilities. Siting difficulty is the subject of widespread discussion, but because of the complexity of the problem, potential solutions are not obvious or well understood. This paper presents a two-step policy-level framework that first develops an empirical measure of siting difficulty and then qualitatively assesses its major causes. The approach is based on the creation and aggregation of four siting indicators that are independent of the common causes and localized effects of siting problems. The proposed framework is demonstrated for the case of US transmission line siting. Results of the analyses reveal significant variations in state siting difficulty and industry experts' perceptions of its dominant causes, with implications for the long-term success of Regional Transmission Organizations (RTOs) and knowledge transfer among siting professionals in the deregulated industry. (author)

SITE-2, Power Plant Siting, Cost, Environment, Seismic and Meteorological Effects

International Nuclear Information System (INIS)

Frigerio, N.A.; Habegger, L.J.; King, R.F.; Hoover, L.J.; Clark, N.A.; Cobian, J.M.

1977-01-01

1 - Description of problem or function: SITE2 is designed to (1) screen candidate energy facility sites or areas within an electric utility region, based on the region's physical and socioeconomic attributes, the planned facility's characteristics, and impact assessments, and (2) evaluate the cumulative regional impacts associated with alternate energy supply options and inter-regional energy import/export practices, specifically, comparison of different energy technologies and their regional distribution in clustered or dispersed patterns. 2 - Method of solution: The SITE2 methodology is based on the quantification of three major site-related vectors. A cost vector is determined which identifies site-specific costs, such as transmission costs, cooling costs as related to water availability, and costs of specific controls needed to protect the surrounding environment. An impact vector is also computed for each potential site, using models of health and environmental impacts incurred in areas adjacent to the site. Finally, a site attribute vector is developed which reflects such characteristics as population, seismic conditions, meteorology, land use, and local ecological systems. This vector can be used to eliminate certain sites because of their inability to satisfy specific constraints. These three vectors can be displayed as density maps and combined in a simple overlay approach, similar to that developed by I. L. McHarg in reference 2, to identify candidate sites. Alternatively, the vector elements can be computationally combined into a weighted sum to obtain quantitative indicators of site suitability

SITE-2, Power Plant Siting, Cost, Environment, Seismic and Meteorological Effects

Energy Technology Data Exchange (ETDEWEB)

Frigerio, N A [Environmental Impact Studies, Argonne National Laboratory 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Habegger, L J; King, R F; Hoover, L J [Energy and Environmental Systems Division, Argonne National Laboratory 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Clark, N A [Applied Mathematics Division, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Cobian, J M [Northwestern University, Evanston, Illinois 60201 (United States)

1977-08-01

1 - Description of problem or function: SITE2 is designed to (1) screen candidate energy facility sites or areas within an electric utility region, based on the region's physical and socioeconomic attributes, the planned facility's characteristics, and impact assessments, and (2) evaluate the cumulative regional impacts associated with alternate energy supply options and inter-regional energy import/export practices, specifically, comparison of different energy technologies and their regional distribution in clustered or dispersed patterns. 2 - Method of solution: The SITE2 methodology is based on the quantification of three major site-related vectors. A cost vector is determined which identifies site-specific costs, such as transmission costs, cooling costs as related to water availability, and costs of specific controls needed to protect the surrounding environment. An impact vector is also computed for each potential site, using models of health and environmental impacts incurred in areas adjacent to the site. Finally, a site attribute vector is developed which reflects such characteristics as population, seismic conditions, meteorology, land use, and local ecological systems. This vector can be used to eliminate certain sites because of their inability to satisfy specific constraints. These three vectors can be displayed as density maps and combined in a simple overlay approach, similar to that developed by I. L. McHarg in reference 2, to identify candidate sites. Alternatively, the vector elements can be computationally combined into a weighted sum to obtain quantitative indicators of site suitability.

Report of early site suitability evaluation of the potential repository site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

Energy Technology Data Exchange (ETDEWEB)

Younker, J.L.; Andrews, W.B.; Fasano, G.A.; Herrington, C.C.; Mattson, S.R.; Murray, R.C. [Science Applications International Corp., Las Vegas, NV (United States); Ballou, L.B.; Revelli, M.A. [Lawrence Livermore National Lab., CA (United States); Ducharme, A.R.; Shephard, L.E. [Sandia National Labs., Albuquerque, NM (United States); Dudley, W.W.; Hoxie, D.T. [Geological Survey, Denver, CO (United States); Herbst, R.J.; Patera, E.A. [Los Alamos National Lab., NM (United States); Judd, B.R. [Decision Analysis Co., Portola Valley, CA (United States); Docka, J.A.; Rickertsen, L.D. [Weston Technical Associates, Washington, DC (United States)

1992-01-01

This study evaluated the technical suitability of Yucca Mountain, Nevada, as a potential site for a mined geologic repository for the permanent disposal of radioactive waste. The evaluation was conducted primarily to determine early in the site characterization program if there are any features or conditions at the site that indicate it is unsuitable for repository development. A secondary purpose was to determine the status of knowledge in the major technical areas that affect the suitability of the site. This early site suitability evaluation (ESSE) was conducted by a team of technical personnel at the request of the Associate Director of the US Department of Energy (DOE) Office of Geologic Disposal, a unit within the DOE`s Office of Civilian Radioactive Waste Management. The Yucca Mountain site has been the subject of such evaluations for over a decade. In 1983, the site was evaluated as part of a screening process to identify potentially acceptable sites. The site was evaluated in greater detail and found suitable for site characterization as part of the Environmental Assessment (EA) (DOE, 1986) required by the Nuclear Waste Policy Act of 1982 (NWPA). Additional site data were compiled during the preparation of the Site Characterization Plan (SCP) (DOE, 1988a). This early site suitability evaluation has considered information that was used in preparing both-documents, along with recent information obtained since the EA and SCP were published. This body of information is referred to in this report as ``current information`` or ``available evidence.``

One-site versus two-site phacotrabeculectomy: a prospective randomized study

Directory of Open Access Journals (Sweden)

Moschos MM

2015-08-01

Full Text Available Marilita M Moschos,1 Irini P Chatziralli,2 Michael Tsatsos3 1First Department of Ophthalmology, University of Athens, 2Second Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece; 3Department of Ophthalmology, Cambridge University Hospital NHS, Cambridge, UK Purpose: The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation.Methods: Thirty-four patients (41 eyes with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes or a two-site (19 eyes combined procedure. One-site approach consisted of a standard superior phacotrabeculectomy with a limbus-based conjunctival flap, while two-site approach consisted of a clear cornea phacoemulsification and a separate superior trabeculectomy with a limbus-based conjunctival flap.Results: Mean follow-up period was 54 months (standard deviation [SD] 2.3. Mean preoperative intraocular pressure (IOP in the one-site group was 21.3 mmHg (SD 2.8 and in the two-site group was 21.8 mmHg (SD 3.0 (P>0.1. Mean postoperative IOP significantly decreased in both groups compared to the preoperative level and was 15.6 mmHg (SD 3.5 in the one-site group and 14.9 mmHg (SD 2.7 in the two-site group. Three months later, the difference between the two groups was not statistically significant (P=0.058. The one-site group required significantly more medications than the two-site group (P=0.03. Best-corrected visual acuity (BCVA improved similarly in both groups, but there was less postoperative (induced astigmatism in the two-site group in a marginal statistical level (P=0.058. Intra- and postoperative complications were comparable in the two groups.Conclusion: Both techniques yielded similar results concerning final BCVA and IOP reduction. However, the two-site group had less induced astigmatism and a better postoperative IOP control with less required

Remediation management of complex sites using an adaptive site management approach.

Science.gov (United States)

Price, John; Spreng, Carl; Hawley, Elisabeth L; Deeb, Rula

2017-12-15

Complex sites require a disproportionate amount of resources for environmental remediation and long timeframes to achieve remediation objectives, due to their complex geologic conditions, hydrogeologic conditions, geochemical conditions, contaminant-related conditions, large scale of contamination, and/or non-technical challenges. A recent team of state and federal environmental regulators, federal agency representatives, industry experts, community stakeholders, and academia worked together as an Interstate Technology & Regulatory Council (ITRC) team to compile resources and create new guidance on the remediation management of complex sites. This article summarizes the ITRC team's recommended process for addressing complex sites through an adaptive site management approach. The team provided guidance for site managers and other stakeholders to evaluate site complexities and determine site remediation potential, i.e., whether an adaptive site management approach is warranted. Adaptive site management was described as a comprehensive, flexible approach to iteratively evaluate and adjust the remedial strategy in response to remedy performance. Key aspects of adaptive site management were described, including tools for revising and updating the conceptual site model (CSM), the importance of setting interim objectives to define short-term milestones on the journey to achieving site objectives, establishing a performance model and metrics to evaluate progress towards meeting interim objectives, and comparing actual with predicted progress during scheduled periodic evaluations, and establishing decision criteria for when and how to adapt/modify/revise the remedial strategy in response to remedy performance. Key findings will be published in an ITRC Technical and Regulatory guidance document in 2017 and free training webinars will be conducted. More information is available at www.itrc-web.org. Copyright © 2017 Elsevier Ltd. All rights reserved.

Nuclear installations sites safety

International Nuclear Information System (INIS)

Barber, P.; Candes, P.; Duclos, P.; Doumenc, A.; Faure, J.; Hugon, J.; Mohammadioun, B.

1988-11-01

This report is divided into ten parts bearing: 1 Safety analysis procedures for Basis Nuclear Installations sites (BNI) in France 2 Site safety for BNI in France 3 Industrial and transport activities risks for BNI in France 4 Demographic characteristics near BNI sites in France 5 Meteorologic characteristics of BNI sites in France 6 Geological aspects near the BNI sites in France 7 Seismic studies for BNI sites in France 8 Hydrogeological aspects near BNI sites in France 9 Hydrological aspects near BNI sites in France 10 Ecological and radioecological studies of BNI sites in France [fr

Site locality identification study: Hanford Site. Volume II. Data cataloging

International Nuclear Information System (INIS)

1980-07-01

Data compilation and cataloging for the candidate site locality identification study were conducted in order to provide a retrievable data cataloging system for the present siting study and future site evaluation and licensng processes. This task occurred concurrently with and also independently of other tasks of the candidate site locality identification study. Work in this task provided the data utilized primarily in the development and application of screening and ranking processes to identify candidate site localities on the Hanford Site. The overall approach included two steps: (1) data acquisition and screening; and (2) data compilation and cataloging. Data acquisition and screening formed the basis for preliminary review of data sources with respect to their probable utilization in the candidate site locality identification study and review with respect to the level of completeness and detail of the data. The important working assumption was that the data to be used in the study be based on existing and available published and unpublished literature. The data compilation and cataloging provided the basic product of the Task; a retrievable data cataloging system in the form of an annotated reference list and key word index and an index of compiled data. The annotated reference list and key word index are cross referenced and can be used to trace and retrieve the data sources utilized in the candidate site locality identification study

Towards a Concerted Effort

DEFF Research Database (Denmark)

Johansen, Mette-Louise; Mouritsen, Tina; Montgomery, Edith

2006-01-01

This book contains a method model for the prevention of youth crime in Danish municipalities. The method model consists of instructions for conducting processual network meetings between traumatized refugee parents and the professional specialists working with their children on an intermunicipal...

AIDA: concerted calorimeter development

CERN Multimedia

Felix Sefkow

2013-01-01

AIDA – the EU-funded project bringing together more than 80 institutes worldwide – aims at developing new detector solutions for future accelerators. Among the highlights reported at AIDA’s recent annual meeting in Frascati was the completion of an impressive calorimeter test beam programme, conducted by the CALICE collaboration over the past two years at CERN’s PS and SPS beam lines.   The CALICE tungsten calorimeter prototype under test at CERN. This cubic-metre hadron calorimeter prototype has almost 500,000 individually read-out electronics channels – more than all the calorimeters of ATLAS and CMS put together. Calorimeter development in AIDA is mainly motivated by experiments at possible future electron-positron colliders, namely ILC or CLIC. The physics requirements of such future machines demand extremely high-performance calorimetry. This is best achieved using a finely segmented system that reconstructs events using the so-called pa...

Site locality identification study: Hanford Site. Volume I. Methodology, guidelines, and screening

International Nuclear Information System (INIS)

1980-07-01

Presented in this report are the results of the site locality identification study for the Hanford Site using a screening process. To enable evaluation of the entire Hanford Site, the screening process was applied to a somewhat larger area; i.e., the Pasco Basin. The study consisted of a series of screening steps that progressively focused on smaller areas which are within the Hanford Site and which had a higher potential for containing suitable repository sites for nuclear waste than the areas not included for further study. Five site localities, designated H-1, H-2, H-3, H-4, H-5 (Figure A), varying in size from approximately 10 to 50 square miles, were identified on the Hanford Site. It is anticipated that each site locality may contain one or more candidate sites suitable for a nuclear waste repository. The site locality identification study began with definition of objectives and the development of guidelines for screening. Three objectives were defined: (1) maximize public health and safety; (2) minimize adverse environmental and socioeconomic impacts; and (3) minimize system costs. The screening guidelines have numerical values that provided the basis for the successive reduction of the area under study and to focus on smaller areas that had a higher likelihood of containing suitable sites

Providing an integrated waste management strategy and operation focused on project end states at the Hanford site

International Nuclear Information System (INIS)

Blackford, L.

2009-01-01

responsibilities; 3) provides a basis for budgeting; and 4) reflects a concerted goal of achieving full regulatory compliance and remediation (with enforceable milestones) in an aggressive manner. CHPRC's approach to safely accelerate and accomplish solid waste stabilization and disposition provides an integrated waste management (WM) strategy and operation focused on project end states. CHPRC will present planned approaches for waste stabilization and disposition based on lessons learned at other DOE sites and discuss optimizing solutions to accelerating TPA milestone M-91 TRU waste retrieval activities through innovation and increased production, Point of Generation waste management, unique transport and packaging systems that are re-usable, and in-field waste handling and treatment processes that have generated cost saving and are generating early-completion cost savings of $66 million on the PRC that can be redirected to other pressing Hanford Plateau Remediation Contract (PRC) projects. (authors)

External communication FY 1995 Site Support Program Plan WBS 6.10.6

International Nuclear Information System (INIS)

Whiting, W.P.

1994-09-01

External Communications activities provide value to the company, its projects, and DOE by achieving compliance to more than 30 DOE orders, DOE directives, policies, state and federal laws. Through the systematic development of informed consent involving Hanford management, stakeholders, the general public and regulators, Hanford cleanup is better able to proceed in concert with involved parties. External Communications provides further efficiencies as the single point of contact for media interactions which otherwise would be scattered throughout WHC programs. Enhanced efficiency is expected from the realignment of multi-purpose communication teams which are dedicated to five key programmatic areas: TWRS Communications, Transition Facilities Communications, Spent Fuels Communications, Waste, Analytical and Environmental Services Communications, and Program Communications Services

1 Étude numérique de la convection naturelle tridimensionnelle ...

African Journals Online (AJOL)

TOSHIBA

naturelle thermique laminaire de type couche limite au voisinage d'un cône à surface lisse. Bapuji et al. [2] ont étudié le courant de la convection naturelle laminaire instable avec un cône vertical isotherme. Pop et. Tsung Yen [3] ont étudié les effets de la compressibilité dans la convection naturelle laminaire autour d'un.

Composition chimique et activité antibactérienne des Huiles ...

African Journals Online (AJOL)

car la recherche des nouveaux médicaments est continuelle [1]. Les limites ... les huiles essentielles offre de nouvelles perspectives thérapeutiques. En effet, depuis quelques années, un intérêt accru est porté sur les huiles essentielles ayant montré des .... essentielle par mesure du diamètre d'inhibition, autour d'un disque ...

Effets de présence, délocalisations et relocalisations des images : le médium en quête d’espace ?

Directory of Open Access Journals (Sweden)

Benjamin Philippe Léon

2014-07-01

Full Text Available Retour sur la “XII MAGIS - Gorizia International Film Studies Spring School”, qui aura permis durant une semaine d’élaborer une somme de réflexions autour des images à l’heure du contemporain. Une conférence aux réflexions stimulantes et stimulées par l’approche plurielle du “FilmForum”.

Author Details

African Journals Online (AJOL)

Son, Gouyahali. Vol 10, No 3 (2016) - Articles Analyse des systèmes de production de l'oignon bulbe autour du barrage de Goinré dans la province du Yatenga au Nord du Burkina Faso Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

South Asia | Page 6 | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

Read more about Call for civil registration and vital statistics systems experts. Language English. Une travailleuse de pierre. Photo : Mohammad Rakibul Hasan/ ONU Femmes. Autour du monde, les inégalités entre les sexes dans le domaine de l'éducation diminuent et les taux de fertilité sont en déclin. À mesure que les ...

2. Serge Bernard.pmd

African Journals Online (AJOL)

chifaou.amzat

19 mai 2017 ... pas gratuit. La définition et l'histoire du concept nous en fournissent la preuve. ... principes les plus essentiels de la démocratie et de l'État de droit, le Livre ... autour d'un arbre ou simplement dans un lieu public, en Afrique, « les ...... Revue internationale des Sciences sociales, n° 155, Éditions Unesco.

Technologies d'information et de la communication dans la gestion ...

International Development Research Centre (IDRC) Digital Library (Canada)

Ce projet a le double objectif d'appuyer un projet de recherche-action sur les systèmes d'information géographiques participatifs (SIG-P) pour le développement local en Afrique et de jeter les bases d'une plateforme de collaboration autour de la problématique des technologies d'information et de la communication (TIC) et ...

Méditerranée asiatique : un modèle urbain polycentrique

OpenAIRE

Gipouloux , François

2012-01-01

Publication de la revue "Diplomatie. Affaires stratégiques et relations internationales" http://www.diplomatie-presse.com/; International audience; En Asie orientale, un corridor maritime a pris forme autour de plates-formes logistiques et portuaires, fidèles au modèle de Hong Kong. C'est là que bat le coeur de l'économie régionale.

Site Features

Data.gov (United States)

U.S. Environmental Protection Agency — This dataset consists of various site features from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times...

Nevada Test Site Environmental Report 2007 Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills

2008-09-01

This appendix expands on the general description of the Nevada Test Site (NTS) presented in the Introduction to the Nevada Test Site Environmental Report 2007 (U.S. Department of Energy [DOE], 2008). Included are subsections that summarize the site's geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site which afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Hanford Site Development Plan

International Nuclear Information System (INIS)

Rinne, C.A.; Curry, R.H.; Hagan, J.W.; Seiler, S.W.; Sommer, D.J.; Yancey, E.F.

1990-01-01

The Hanford Site Development Plan (Site Development Plan) is intended to guide the short- and long-range development and use of the Hanford Site. All acquisition, development, and permanent facility use at the Hanford Site will conform to the approved plan. The Site Development Plan also serves as the base document for all subsequent studies that involve use of facilities at the Site. This revision is an update of a previous plan. The executive summary presents the highlights of the five major topics covered in the Site Development Plan: general site information, existing conditions, planning analysis, Master Plan, and Five-Year Plan. 56 refs., 67 figs., 31 tabs

Hanford Site Development Plan

Energy Technology Data Exchange (ETDEWEB)

Rinne, C.A.; Curry, R.H.; Hagan, J.W.; Seiler, S.W.; Sommer, D.J. (Westinghouse Hanford Co., Richland, WA (USA)); Yancey, E.F. (Pacific Northwest Lab., Richland, WA (USA))

1990-01-01

The Hanford Site Development Plan (Site Development Plan) is intended to guide the short- and long-range development and use of the Hanford Site. All acquisition, development, and permanent facility use at the Hanford Site will conform to the approved plan. The Site Development Plan also serves as the base document for all subsequent studies that involve use of facilities at the Site. This revision is an update of a previous plan. The executive summary presents the highlights of the five major topics covered in the Site Development Plan: general site information, existing conditions, planning analysis, Master Plan, and Five-Year Plan. 56 refs., 67 figs., 31 tabs.

Entry and exit of bacterial outer membrane proteins.

Science.gov (United States)

Misra, Rajeev

2015-08-01

The sites of new outer membrane protein (OMP) deposition and the fate of pre-existing OMPs are still enigmatic despite numerous concerted efforts. Rassam et al. identified mid-cell regions as the primary entry points for new OMP insertion in clusters, driving the pre-existing OMP clusters towards cell poles for long-term storage. Copyright © 2015 Elsevier Ltd. All rights reserved.

Technical summary of groundwater quality protection program at the Savannah River Site, 1952--1986. Volume 1, Site geohydrology and waste sites

Energy Technology Data Exchange (ETDEWEB)

Heffner, J.D. [ed.] [Exploration Resources, Inc., Athens, GA (United States)

1991-11-01

This report provides information regarding the status of and groundwater quality at the waste sites at the Department of Energy`s (DOE) Savannah River Site (SRS). Specific information provided for each waste site at SRS includes its location, size, inventory (when known), and history. Many waste sites at SRS are considered to be of little environmental concern because they contain nontoxic or inert material such as construction rubble and debris. Other waste sites, however, either are known to have had an effect on groundwater quality or are suspected of having the potential to affect groundwater. Monitoring wells have been installed at most of these sites; monitoring wells are scheduled for installation at the remaining sites. Results of the groundwater analyses from these monitoring wells, presented in the appendices, are used in the report to help identify potential contaminants of concern, if any, at each waste site. The list of actions proposed for each waste site in Christensen and Gordon`s 1983 report are summarized, and an update is provided for each site. Planned actions for the future are also outlined.

New Reactor Siting in Finland, Hanhikivi Site in Pyhaejoki - STUK preliminary safety assessment

International Nuclear Information System (INIS)

Nevalainen, Janne

2013-01-01

STUK has performed a preliminary assessment of the Decision-in-Principle on the Fennovoima application. A variety of factors must be considered in the selection of a site, including effects of the site on the plant design and the effects of the plant on the site environment. These include external hazards, both natural and human-induced. Since this is a new site, an extensive siting process is followed, that can include an EIA. A site survey is performed to identify candidate sites, after investigating a large region and rejecting unsuitable sites. The remaining sites are then screened and compared on the basis of safety and other considerations to select one or more preferred sites. Natural hazards include geology, seismology, hydrology and meteorology. Offshore ice will be a particular hazard for this plant, since the site is on average only 1.5 m above sea level. The design basis earthquake corresponds to a return frequency of 100,000 years, with 50 % confidence. The existing sites in southern Finland used a design peak ground acceleration of 0.1 g with the ground response spectrum maximum at 10 Hz. The candidate sites in northern Finland will require a peak ground acceleration of 0.2 g with the ground response spectrum maximum at 25 Hz

Hydrogeological Site Descriptive Model - a strategy for its development during Site Investigations

Energy Technology Data Exchange (ETDEWEB)

Rhen, Ingvar [SWECO VIAK AB, Goeteborg (Sweden); Follin, Sven [SF GeoLogic AB, Stockholm (Sweden); Hermanson, Jan [Golder Associates, Stockholm (Sweden)

2003-04-01

The report is to present a strategy for the development of the Site Descriptive Hydrogeological Model within the SKB Site Investigation Programme. The report, and similar reports from the Geology, Rock Mechanics, Thermal properties, Hydrogeochemistry, Transport Properties and Surface Ecosystem disciplines are intended to guide SKB Site Descriptive Modelling but also to provide the authorities with an overview of how the modelling should be performed. Thus the objectives of this report are to: provide guidelines for the modelling of different sites resulting in consistent handling of modelling issues during the Site Investigations, provide a structure for the modelling sequence that is suitable for the establishment of a Site Descriptive model and provide some necessary details that should be considered in a Site Descriptive model.

Hydrogeological Site Descriptive Model - a strategy for its development during Site Investigations

International Nuclear Information System (INIS)

Rhen, Ingvar; Follin, Sven; Hermanson, Jan

2003-04-01

The report is to present a strategy for the development of the Site Descriptive Hydrogeological Model within the SKB Site Investigation Programme. The report, and similar reports from the Geology, Rock Mechanics, Thermal properties, Hydrogeochemistry, Transport Properties and Surface Ecosystem disciplines are intended to guide SKB Site Descriptive Modelling but also to provide the authorities with an overview of how the modelling should be performed. Thus the objectives of this report are to: provide guidelines for the modelling of different sites resulting in consistent handling of modelling issues during the Site Investigations, provide a structure for the modelling sequence that is suitable for the establishment of a Site Descriptive model and provide some necessary details that should be considered in a Site Descriptive model

Computer aided site management. Site use management by digital mapping

International Nuclear Information System (INIS)

Chupin, J.C.

1990-01-01

The logistics program developed for assisting the Hague site management is presented. A digital site mapping representation and geographical data bases are used. The digital site map and its integration into a data base are described. The program can be applied to urban and rural land management aid. Technical administrative and economic evaluations of the program are summarized [fr

Brain scaling in mammalian evolution as a consequence of concerted and mosaic changes in numbers of neurons and average neuronal cell size

Directory of Open Access Journals (Sweden)

Suzana eHerculano-Houzel

2014-08-01

Full Text Available Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific characteristics of 41 modern mammalian species in 6 clades, and in light of the phylogenetic relationships among them, here we propose that ancestral mammal brains were composed and scaled in their cellular composition like modern afrotherian and glire brains: with an addition of neurons that is accompanied by a decrease in neuronal density and very little modification in glial cell density, implying a significant increase in average neuronal cell size in larger brains, and the allocation of approximately 2 neurons in the cerebral cortex and 8 neurons in the cerebellum for every neuron allocated to the rest of brain. We also propose that in some clades the scaling of different brain structures has diverged away from the common ancestral layout through clade-specific (or clade-defining changes in how average neuronal cell mass relates to numbers of neurons in each structure, and how numbers of neurons are differentially allocated to each structure relative to the number of neurons in the rest of brain. Thus, the evolutionary expansion of mammalian brains has involved both concerted and mosaic patterns of scaling across structures. This is, to our knowledge, the first mechanistic model that explains the generation of brains large and small in mammalian evolution, and it opens up new horizons for seeking the cellular pathways and genes involved in brain evolution.

Concerted evolution of the tandemly repeated genes encoding primate U2 small nuclear RNA (the RNU2 locus) does not prevent rapid diversification of the (CT){sub n} {center_dot} (GA){sub n} microsatellite embedded within the U2 repeat unit

Energy Technology Data Exchange (ETDEWEB)

Liao, D.; Weiner, A.M. [Yale Univ., New Haven, CT (United States)

1995-12-10

The RNU2 locus encoding human U2 small nuclear RNA (snRNA) is organized as a nearly perfect tandem array containing 5 to 22 copies of a 5.8-kb repeat unit. Just downstream of the U2 snRNA gene in each 5.8-kb repeat unit lies a large (CT){sub n}{center_dot}(GA){sub n} dinucleotide repeat (n {approx} 70). This form of genomic organization, in which one repeat is embedded within another, provides an unusual opportunity to study the balance of forces maintaining the homogeneity of both kinds of repeats. Using a combination of field inversion gel electrophoresis and polymerase chain reaction, we have been able to study the CT microsatellites within individual U2 tandem arrays. We find that the CT microsatellites within an RNU2 allele exhibit significant length polymorphism, despite the remarkable homogeneity of the surrounding U2 repeat units. Length polymorphism is due primarily to loss or gain of CT dinucleotide repeats, but other types of deletions, insertions, and substitutions are also frequent. Polymorphism is greatly reduced in regions where pure (CT){sub n} tracts are interrupted by occasional G residues, suggesting that irregularities stabilize both the length and the sequence of the dinucleotide repeat. We further show that the RNU2 loci of other catarrhine primates (gorilla, chimpanzee, ogangutan, and baboon) contain orthologous CT microsatellites; these also exhibit length polymorphism, but are highly divergent from each other. Thus, although the CT microsatellite is evolving far more rapidly than the rest of the U2 repeat unit, it has persisted through multiple speciation events spanning >35 Myr. The persistence of the CT microsatellite, despite polymorphism and rapid evolution, suggests that it might play a functional role in concerted evolution of the RNU2 loci, perhaps as an initiation site for recombination and/or gene conversion. 70 refs., 5 figs.

Site characterization quality assurance for the California LLRW Disposal Site Project

International Nuclear Information System (INIS)

Hanrahan, T.P.; Ench, J.E.; Serlin, C.L.; Bennett, C.B.

1988-01-01

In December of 1985 US Ecology was chosen as the license designee for the State of California's low-level radioactive waste disposal facility. In early 1987, three candidate sites were selected for characterization studies in preparation for identifying the preferred site. The geotechnical characterization activities along with studies of the ecological and archaeological attributes, as well as assessments of the socio-economic impacts and cultural resources all provide input towards selection of the proposed site. These technical studies in conjunction with comments from local citizen committees and other interested parties are used as a basis for determining the proposed site for which full site characterization as required by California licensing requirements are undertaken. The purpose of this paper is to present an overview of the program for Quality Assurance and Quality Control for the site characterization activities on the California LLRW Disposal Site Project. The focus is on three major perspectives: The composite QA Program and two of the primary characterization activities, the geotechnical and the meteorological investigations

Site selection

International Nuclear Information System (INIS)

Olsen, C.W.

1983-07-01

The conditions and criteria for selecting a site for a nuclear weapons test at the Nevada Test Site are summarized. Factors considered are: (1) scheduling of drill rigs, (2) scheduling of site preparation (dirt work, auger hole, surface casing, cementing), (3) schedule of event (when are drill hole data needed), (4) depth range of proposed W.P., (5) geologic structure (faults, Pz contact, etc.), (6) stratigraphy (alluvium, location of Grouse Canyon Tuff, etc.), (7) material properties (particularly montmorillonite and CO 2 content), (8) water table depth, (9) potential drilling problems (caving), (10) adjacent collapse craters and chimneys, (11) adjacent expended but uncollapsed sites, (12) adjacent post-shot or other small diameter holes, (13) adjacent stockpile emplacement holes, (14) adjacent planned events (including LANL), (15) projected needs of Test Program for various DOB's and operational separations, and (16) optimal use of NTS real estate

Site-Specific Atmospheric Dispersion Characteristics of Korean Nuclear Power Plant Sites

International Nuclear Information System (INIS)

Han, M. H.; Kim, E. H.; Suh, K. S.; Hwang, W. T.; Choi, Y. G.

2001-01-01

Site-specific atmospheric dispersion characteristics have been analyzed. The northwest and the southwest wind prevail on nuclear sites of Korea. The annual isobaric surface averaged for twenty years around Korean peninsula shows that west wind prevails. The prevailing west wind is profitable in the viewpoint of radiation protection because three of four nuclear sites are located in the east side. Large scale field tracer experiments over nuclear sites have been conducted for the purpose of analyzing the atmospheric dispersion characteristics and validating a real-time atmospheric dispersion and dose assessment system FADAS. To analyze the site-specific atmospheric dispersion characteristics is essential for making effective countermeasures against a nuclear emergency

29 CFR 1926.752 - Site layout, site-specific erection plan and construction sequence.

Science.gov (United States)

2010-07-01

... 29 Labor 8 2010-07-01 2010-07-01 false Site layout, site-specific erection plan and construction... Steel Erection § 1926.752 Site layout, site-specific erection plan and construction sequence. (a... strength or sufficient strength to support the loads imposed during steel erection. (c) Site layout. The...

Rééquilibrage des temps autour de la retraite

Directory of Open Access Journals (Sweden)

Anca Boboc

2012-06-01

Full Text Available Le passage à la retraite ne se réduit pas à une date séparant hermétiquement deux périodes disjointes de l’existence. D’une part, ce passage présente une certaine durée, s’étendant de part et d’autre de la date formelle de « cessation d’activité ». D’autre part, le temps de la retraite est aussi l’occasion d’entreprendre des activités qui, nouvelles ou en prolongement, s’inscrivent dans le parcours antérieur des individus. Plus précisément, ce passage particulier est l’occasion de repenser l’organisation des différentes temporalités sociales, d’articuler différemment activités professionnelles — pour ceux qui cumulent emploi et retraite —, associatives, familiales, artistiques, ludiques, etc. Il en résulte une diversité des parcours de retraite, comme permet de l’apprécier la variété des activités qu’entreprennent les retraités. Si cette diversité est le reflet d’une certaine autonomie dans les choix des acteurs, elle dépend également des libertés de choix — « capacités » — qui leur sont réellement accessibles. Dans ce sens, l’article examine les apports et les limites d’un raisonnement en termes d’« environnement capacitant », pour rendre compte de l’inégale distribution des capacités à s’emparer des opportunités offertes par la retraite.Plus précisément, l’environnement capacitant désignera l’ensemble constitué des cadres temporels dans lesquels les individus construisent leurs parcours de vie avant la retraite. Dans ce sens, on peut identifier trois cadres temporels constitutifs des parcours de vie : l’axe des politiques macro-économiques, celui des politiques d’entreprise (ou sectorielles et celui des biographies familiales. Chacun de ces trois cadres est lui-même le lieu d’une tension entre « temps comptables » rigides et « temps vécus » caractérisés par une plus grande souplesse temporelle. Selon la résultante de ces tensions, les individus vont développer ou non des capacités à repenser leur organisation temporelle, inventer des « temps à soi », au moment du passage à la retraite.The switch to retirement cannot be reduced to a date that separates two disjointed periods of existence in a strict way. On one hand, this switch takes place on a certain duration of time, before and after the formal date when activity stops. One the other hand, retirement is the occasion to undertake activities, whether new ones or the prolongation of former ones, that spring from the individuals’anterior path. More precisely, this particular switch is an occasion to think again on the organisation of social temporalities, and to rearticulate activities in a new way : professional activities (for the ones who keep a job along their retirement as well as family, artistic, leisure activities. A diversity of retirement paths can be derived from this constatation, as can be observed from the variety of activities that pensioners undertake. This diversity reflects a certain autonomy in the choices that actors make, but it also depends on the choices (« capabilites » that they can actually reach. In this sense, this paper reviews the advantages and limits of an approach in terms of an « enabling environment », in order to account for the unequal distribution of the capabilities to grasp the opportunities of retirement. More precisely, an « enabling environment » is considered here as all the temporal frameworks for the individuals to build their life paths before retirement. In this sense, three temporal frameworks can be identified : the macro-economic policies, business (or sector policies, and family biographies. Each of these three frameworks hosts tensions between rigid « accounting time » and more flexible « lived time ». Depending on what will come out of these tensions, individuals will or won’t be able to develop the capabilities to think about their temporal organisation and to invent « time for themselves » when they switch towards retirement.

Radiological assessment around CYCERON; Bilan radiologique autour de CYCERON

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-03-15

In the frame of a radiological assessment around the medical research center of Cyceron located at Caen, the A.C.R.O. has realised at the end of 2003 a study defined by three approaches: to make an inventory of the gamma emitter radioisotopes present in the different compartments of the environment; to check outside the building, the level of exposure due to the gamma radiation; to check outside the building, the level of exposure due to the neutrons emitted during a session of production of radionuclides with the cyclotron. The analysis made on soils put in evidence the presence at significant levels, of cesium 137 ({sup 137}Cs), fission product of thirty years period. The presence of {sup 137}Cs does not come from the Cyceron activities, the cyclotron cannot create fission products. In fact, this radioisotope has for origin, the atmospheric tests of nuclear weapons made in the past, and the accident occurring at the Chernobylsk power plant in 1986. The levels are varying from some becquerels by kilogram of dry matter to a decade of becquerels by kilogram of dry matter. For the natural radioactivity the results are in compliance with those expected. Independently of the functioning of the installation, we observe an increase of the ambient gamma radiation only near radioactive waste storage. It result of the storage of the former cyclotron elements. The induced increase is moderated because at 5 meters the values do not exceed the background noise. In relation with the functioning of the installation an increase of the ambient gamma radiation is noticed. Two causes are to considered: the release of radionuclides in atmosphere with gaseous effluents and the radiance of radiation sources inside the building. After the stopping of the installation (48 h at least), no increase of gamma radiation is observed. About the neutrons monitoring, the measures made during the cyclotron functioning, highlight the lack of significant overexposure around the blockhouse at the level of man, a very net increase of the ambient neutron radiation (about 20 times the background noise) exclusively on the roof of the blockhouse. (N.C.)

Dynamique communautaire autour de la gestion de la sante ...

African Journals Online (AJOL)

importance de certains facteurs, en l'occurrence les perceptions culturelles qui rendent pourtant compte de la dimension sociale, culturelle et symbolique de la grossesse. Une telle situation ne peut que compromettre l'atteinte des Objectifs 4 et 5 du ...

Contaminated Sites in Iowa

Data.gov (United States)

Iowa State University GIS Support and Research Facility — Sites contaminated by hazardous materials or wastes. These sites are those administered by the Contaminated Sites Section of Iowa DNR. Many are sites which are...

Hanford Site Development Plan

International Nuclear Information System (INIS)

Hathaway, H.B.; Daly, K.S.; Rinne, C.A.; Seiler, S.W.

1993-05-01

The Hanford Site Development Plan (HSDP) provides an overview of land use, infrastructure, and facility requirements to support US Department of Energy (DOE) programs at the Hanford Site. The HSDP's primary purpose is to inform senior managers and interested parties of development activities and issues that require a commitment of resources to support the Hanford Site. The HSDP provides an existing and future land use plan for the Hanford Site. The HSDP is updated annually in accordance with DOE Order 4320.1B, Site Development Planning, to reflect the mission and overall site development process. Further details about Hanford Site development are defined in individual area development plans

Exploration d’un système interfacique et de ses dynamiques : application au tourisme de réunions et de congrès

Directory of Open Access Journals (Sweden)

Christofle S.

2012-10-01

Full Text Available Le tourisme de réunions et de congrès fait se rassembler en un lieu nodal, durant au moins deux jours, des personnes issues d’horizons géographiques variés mais aux intérêts communs. Le système interfacique congressuel se structure autour de la réunion, interface immatérielle, qui prend place dans le palais des congrès, interface matérielle, et met en contact différents acteurs : congressistes, organisateurs, prestataires de services, collectivités territoriales. Ce système ouvert, localisé, s’articule autour de trois grands types d’interfaces, intra-réticulaires, inter-réseaux et réseaux-territoires dans le cadre de stratégies économiques, de destination et de développement territorial. Quatre grands effets sont induits : la diffusion et l’appropriation d’une information neuve, l’accélération de l’innovation et de l’expérimentation, la création d‘une expérience communautaire, le développement de la valeur.

Site Calibration report

DEFF Research Database (Denmark)

Yordanova, Ginka; Vesth, Allan

The report describes site calibration measurements carried out on a site in Denmark. The measurements are carried out in accordance to Ref. [1]. The site calibration is carried out before a power performance measurement on a given turbine to clarify the influence from the terrain on the ratio...

Site directed recombination

Science.gov (United States)

Jurka, Jerzy W.

1997-01-01

Enhanced homologous recombination is obtained by employing a consensus sequence which has been found to be associated with integration of repeat sequences, such as Alu and ID. The consensus sequence or sequence having a single transition mutation determines one site of a double break which allows for high efficiency of integration at the site. By introducing single or double stranded DNA having the consensus sequence flanking region joined to a sequence of interest, one can reproducibly direct integration of the sequence of interest at one or a limited number of sites. In this way, specific sites can be identified and homologous recombination achieved at the site by employing a second flanking sequence associated with a sequence proximal to the 3'-nick.

Nevada National Security Site Environmental Report 2011 Attachment A: Site Description

International Nuclear Information System (INIS)

Wills, Cathy

2012-01-01

This attachment expands on the general description of the Nevada National Security Site (NNSS) presented in the Introduction to the Nevada National Security Site Environmental Report 2011. Included are subsections that summarize the site's geological, hydrological, climatological, and ecological setting and the cultural resources of the NNSS. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NNSS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NNSS. The NNSS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NNSS operations. These key features include the general remote location of the NNSS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

JUVENIS CONCERT ДЛЯ ФОРТЕПИАНО С ОРКЕСТРОМ ВЛАДИМИРА ЧОЛАКА: ЧЕРТЫ ЖАНРА И ФОРМЫ

Directory of Open Access Journals (Sweden)

COCEAROVA GALINA

2016-12-01

Full Text Available Th e article concerns the problem of implementation of genre features and forms of the piano concerto in the work Juvenis concert by Vladimir Cholak. Devoted to the son of the composer, it sounded in its second edition at the Festival Days of New Music (June 10, 2015, soloist - Natalia Botnariuc, Symphony Orchestra of Teleradio Moldova conducted by Denis Chausov, recording posted on the Internet July 31, 2015

Hanford Site Infrastructure Plan

International Nuclear Information System (INIS)

1990-01-01

The Hanford Site Infrastructure Plan (HIP) has been prepared as an overview of the facilities, utilities, systems, and services that support all activities on the Hanford Site. Its purpose is three-fold: to examine in detail the existing condition of the Hanford Site's aging utility systems, transportation systems, Site services and general-purpose facilities; to evaluate the ability of these systems to meet present and forecasted Site missions; to identify maintenance and upgrade projects necessary to ensure continued safe and cost-effective support to Hanford Site programs well into the twenty-first century. The HIP is intended to be a dynamic document that will be updated accordingly as Site activities, conditions, and requirements change. 35 figs., 25 tabs

Open-field test site

Science.gov (United States)

Gyoda, Koichi; Shinozuka, Takashi

1995-06-01

An open-field test site with measurement equipment, a turn table, antenna positioners, and measurement auxiliary equipment was remodelled at the CRL north-site. This paper introduces the configuration, specifications and characteristics of this new open-field test site. Measured 3-m and 10-m site attenuations are in good agreement with theoretical values, and this means that this site is suitable for using 3-m and 10-m method EMI/EMC measurements. The site is expected to be effective for antenna measurement, antenna calibration, and studies on EMI/EMC measurement methods.

Methodology of site studies

International Nuclear Information System (INIS)

Caries, J.C.; Hugon, J.; Grauby, A.

1980-01-01

This methodology consists in an essentially dynamic, estimated and follow-up analysis of the impact of discharges on all the environment compartments, whether natural or not, that play a part in the protection of man and his environment. It applies at two levels, to wit: the choice of site, or the detailed study of the site selected. Two examples of its application will be developed, namely: at the choice of site level in the case of marine sites, and of the detailed study level of the chosen site in that of a riverside site [fr

Assessment of Effectiveness of Geologic Isolation Systems: REFERENCE SITE INITIAL ASSESSMENT FOR A SALT DOME REPOSITORY

Energy Technology Data Exchange (ETDEWEB)

Harwell, M. A.; Brandstetter, A.; Benson, G. L.; Raymond, J. R.; Brandley, D. J.; Serne, R. J.; Soldat, J. K.; Cole, C. R.; Deutsch, W. J.; Gupta, S. K.; Harwell, C. C.; Napier, B. A.; Reisenauer, A. E.; Prater, L. S.; Simmons, C. S.; Strenge, D. L.; Washburn, J. F.; Zellmer, J. T.

1982-06-01

As a methodology demonstration for the Office of Nuclear Waste Isolation (ONWI), the Assessment of Effectiveness of Geologic Isolation Systems (AEGIS) Program conducted an initial reference site analysis of the long-term effectiveness of a salt dome repository. The Hainesville Salt Dome in Texas was chosen to be representative of the Gulf Coast interior salt domes; however, the Hainesville Site has been eliminated as a possible nuclear waste repository site. The data used for this exercise are not adequate for an actual assessment, nor have all the parametric analyses been made that would adequately characterize the response of the geosystem surrounding the repository. Additionally, because this was the first exercise of the complete AEGIS and WASTE Rock Interaction Technology (WRIT) methodology, this report provides the initial opportunity for the methodology, specifically applied to a site, to be reviewed by the community outside the AEGIS. The scenario evaluation, as a part of the methodology demonstration, involved consideration of a large variety of potentially disruptive phenomena, which alone or in concert could lead to a breach in a salt dome repository and to a subsequent transport of the radionuclides to the environment. Without waste- and repository-induced effects, no plausible natural geologic events or processes which would compromise the repository integrity could be envisioned over the one-million-year time frame after closure. Near-field (waste- and repository-induced) effects were excluded from consideration in this analysis, but they can be added in future analyses when that methodology development is more complete. The potential for consequential human intrusion into salt domes within a million-year time frame led to the consideration of a solution mining intrusion scenario. The AEGIS staff developed a specific human intrusion scenario at 100 years and 1000 years post-closure, which is one of a whole suite of possible scenarios. This scenario

SITE: a methodology for assessment of energy facility siting patterns. Regional studies program

International Nuclear Information System (INIS)

Frigerio, N.A.; Habegger, L.J.; King, R.F.; Hoover, L.J.; Clark, N.A.; Cobian, J.M.

1975-08-01

The timely development of the nation's energy production capacity in a manner that minimizes potential adverse local and regional impacts associated with energy facilities requires the use of sophisticated techniques for evaluation of siting alternatives and fuel cycle options. This report is a documentation of the computerized SITE methodology that has been developed for evaluating health, environmental, and socioeconomic impacts related to utilization of alternate sites for energy production within a region of interest. The cost, impact, and attribute vectors, which are generated and displayed on density maps, can be used in a multiparameter overlay process to identify preferable siting areas. The assessment of clustered facilities in energy centers is also possible within the SITE analysis framework. An application of the SITE methodology to Northern Illinois is presented. Also included is a description of the ongoing extension of SITE for the accumulative evaluation of alternative regional energy siting patterns and fuel cycle options. An appendix provides documentation and user information for the SITE computer program

Site Characterization Work Plan for Gnome-Coach Site, New Mexico

Energy Technology Data Exchange (ETDEWEB)

DOE/NV

2001-02-13

Project Gnome was the first nuclear experiment conducted under the U.S. Atomic Energy Commission (AEC), predecessor to the U.S. Department of Energy (DOE), Plowshare Program. Gnome was part of a joint government-industry experiment focused on developing nuclear devices exclusively for peaceful purposes. The intent of the Gnome experiment was to evaluate the effects of a nuclear detonation in a salt medium. Historically, Project Gnome consisted of a single detonation of a nuclear device on December 10, 1961. Since the Gnome detonation, the AEC/DOE has conducted surface restoration, site reconnaissance, and decontamination and decommissioning activities at the site. In addition, annual groundwater sampling is performed under a long-term hydrological monitoring program begun in 1980. Coach, an experiment to be located near the Gnome project, was initially scheduled for 1963. Although construction and rehabilitation were completed for Coach, the experiment was canceled and never executed. Known collectively as Project Gnome-Coach, the site is situated within the Salado Formation approximately 25 miles east of Carlsbad, New Mexico, in Eddy County, and is comprised of nearly 680 acres, of which 60 acres are disturbed from the combined AEC/DOE operations. The scope of this work plan is to document the environmental objectives and the proposed technical site investigation strategies that will be utilized for the site characterization of the project. The subsurface at the Gnome-Coach site has two contaminant sources that are fundamentally different in terms of both their stratigraphic location and release mechanism. The goal of this characterization is to collect data of sufficient quantity and quality to establish current site conditions and to use the data to identify and evaluate if further action is required to protect human health and the environment and achieve permanent closure of the site. The results of these activities will be presented in a subsequent corrective

Hanford Site Development Plan

International Nuclear Information System (INIS)

Hathaway, H.B.; Daly, K.S.; Rinne, C.A.; Seiler, S.W.

1992-05-01

The Hanford Site Development Plan (HSDP) provides an overview of land use, infrastructure, and facility requirements to support US Department of Energy (DOE) programs at the Hanford Site. The HSDP's primary purpose is to inform senior managers and interested parties of development activities and issues that require a commitment of resources to support the Hanford Site. The HSDP provides a land use plan for the Hanford Site and presents a picture of what is currently known and anticipated in accordance with DOE Order 4320.1B. Site Development Planning. The HSDP wig be updated annually as future decisions further shape the mission and overall site development process. Further details about Hanford Site development are defined in individual area development plans

The disposal of Canada's nuclear fuel waste: site screening and site evaluation technology

International Nuclear Information System (INIS)

Davison, C.C.; Brown, A.; Everitt, R.A.; Gascoyne, M.; Kozak, E.T.; Lodha, G.S.; Martin, C.D.; Soonawala, N.M.; Stevenson, D.R.; Thorne, G.A.; Whitaker, S.H.

1994-06-01

The concept for the disposal of Canada's nuclear fuel waste is to dispose of the waste in an underground vault, nominally at 500 m to 1000 m depth, at a suitable site in plutonic rock of the Canadian Shield. The feasibility of this concept and assessments of its impact on the environment and human health, will be documented by AECL in an Environmental Impact Statement (EIS). This report is one of nine primary references for the EIS. It describes the approach and methods that would be used during the siting stage of the disposal project to identify a preferred candidate disposal site and to confirm its suitability for constructing a disposal facility. The siting stage is divided into two distinct but closely related substages, site screening and site evaluation. Site screening would mainly involve reconnaissance investigations of siting regions of the Shield to identify potential candidate areas where suitable vault locations are likely to exist. Site screening would identify a small number of candidate areas where further detailed investigations were warranted. Site evaluation would involve progressively more detailed surface and subsurface investigations of the candidate areas to first identify potentially suitable vault locations within the candidate areas, and then characterize these potential disposal sites to identify the preferred candidate location for constructing the disposal vault. Site evaluation would conclude with the construction of exploratory shafts and tunnels at the preferred vault location, and underground characterization would be done to confirm the suitability of the preferred candidate site. An integrated program of geological, geophysical, hydrogeological, geochemical and geomechanical investigations would be implemented to obtain the geoscience information needed to assess the suitability of the candidate siting areas and candidate sites for locating a disposal vault. The candidate siting areas and candidate disposal vault sites would be

Site observational work plan for the UMTRA Project site at Spook, Wyoming

International Nuclear Information System (INIS)

1995-05-01

The Spook, Wyoming, site observational work plan proposes site-specific activities to achieve compliance with Subpart B of 40 CFR Part 192 (1994) of the final US Environmental Protection Agency (EPA) ground water protection standards 60 FR 2854 (1995) at this Uranium Mill Tailing Remedial Action (UMTRA) Project site. This draft SOWP presents a comprehensive summary of existing site characterization data, a conceptual site model of the nature and extent of ground water contamination, exposure pathways, and potential impact to human health and the environment. Section 2.0 describes the requirements for meeting ground water standards at UMTRA Project sites. Section 3.0 defines past and current conditions, describes potential environmental and human health risks, and provides site-specific data that supports the selection of a proposed ground water compliance strategy. Section 4.0 provides the justification for selecting the proposed ground water compliance strategy based on the framework defined in the ground water programmatic environmental impact statement (PEIS)

2084-IJBCS-Article -Fernique Konan

African Journals Online (AJOL)

hp

Effet antibactérien de l'extrait aqueux de l'écorce de Terminalia glaucescens. Planch ex Benth (Combretaceae) sur la croissance in vitro des ... plantes et 60 à 70% des médicaments antibactériens et anticancéreux sont des substances .... La lecture a été faite par la mesure du diamètre de la zone d'inhibition autour de.

La créativité dans les établissements scolaires. Lancement du projet TRAVcoll 2015-2016

OpenAIRE

Faulx, Daniel

2015-01-01

Dias de présentation de la conférence autour de la créativité et de l'innovation en milieu scolaire. La présentation fait le parallèle entre des éléments de contenus sur la créativité (définition, conditions, objets, durabilité) et des méthodes de développement créatif.

Il Fuoco or the fatal portrait : the XIXth century in the Italian silent cinema

NARCIS (Netherlands)

Blom, I.L.

1992-01-01

Dans les années dix de notre siècle, un genre nouveau de film s'installe en Italie aux côtés des grandes productions historiques : le cinéma des divas dont l'histoire-type tourne autour des drames d'un "ménage à trois". Il Fuoco (Giovanni Pastrone, 1915) serait, selon l'auteur, un film moderne qui,

(Sorghum bicolor (L.) Moench) du Nord du Burkina Faso

African Journals Online (AJOL)

SARAH

29 déc. 2014 ... sorghos à grains sucrés ont un cycle court et arrivent donc à maturité avant les autres sorghos et le mil d'où leur exploitation comme aliment de soudure par les paysans. L'organisation de la diversité morphologique des accessions de sorghos à grains sucrés du Nord du. Burkina autour principalement des ...

Hanford Site Composite Analysis Technical Approach Description: Hanford Site Disposition Baseline.

Energy Technology Data Exchange (ETDEWEB)

Cobb, M. A. [CH2M HILL Plateau Remediation Company, Richland, WA (United States); Dockter, R. E. [CH2M HILL Plateau Remediation Company, Richland, WA (United States)

2017-10-02

The permeability of ground surfaces within the U.S. Department of Energy’s (DOE) Hanford Site strongly influences boundary conditions when simulating the movement of groundwater using the Subsurface Transport Over Multiple Phases model. To conduct site-wide modeling of cumulative impacts to groundwater from past, current, and future waste management activities, a site-wide assessment of the permeability of surface conditions is needed. The surface condition of the vast majority of the Hanford Site has been and continues to be native soils vegetated with dryland grasses and shrubs.

Thioredoxin binding site of phosphoribulokinase overlaps the catalytic site

International Nuclear Information System (INIS)

Porter, M.A.; Hartman, F.C.

1986-01-01

The ATP-regulatory binding site of phosphoribulokinase was studied using bromoacetylethanolamine phosphate (BrAcNHEtOP). BrAcNHEtOP binds to the active-regulatory binding site of the protein. Following trypsin degradation of the labeled protein, fragments were separated by HPLC and sequenced. (DT)

Web sites that work secrets from winning web sites

CERN Document Server

Smith, Jon

2012-01-01

Leading web site entrepreneur Jon Smith has condensed the secrets of his success into 52 inspiring ideas that even the most hopeless technophobe can implement. The brilliant tips and practical advice in Web sites that work will uplift and transform any website, from the simplest to the most complicated. It deals with everything from fundamentals such as how to assess the effectiveness of a website and how to get a site listed on the most popular search engines to more sophisticated challenges like creating a community and dealing with legal requirements. Straight-talking, practical and humorou

Nevada National Security Site Environmental Report 2011 Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills, ed.

2012-09-12

This attachment expands on the general description of the Nevada National Security Site (NNSS) presented in the Introduction to the Nevada National Security Site Environmental Report 2011. Included are subsections that summarize the site's geological, hydrological, climatological, and ecological setting and the cultural resources of the NNSS. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NNSS. An adequate knowledge of the site's environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NNSS. The NNSS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NNSS operations. These key features include the general remote location of the NNSS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Theoretical investigation of the Friedlander reaction catalysed by CuBTC: Concerted effect of the adjacent Cu2+ sites

Czech Academy of Sciences Publication Activity Database

Položij, M.; Pérez-Mayoral, E.; Čejka, Jiří; Hermann, J.; Nachtigall, P.

2013-01-01

Roč. 204, APR 2013 (2013), s. 101-107 ISSN 0920-5861 R&D Projects: GA ČR GBP106/12/G015 Grant - others:European Commission(XE) FP7/2007-2013, contract 228862 Institutional support: RVO:61388955 Keywords : Friedlander reaction * Metal Organic Framework (MOF) * CuBTC Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.309, year: 2013

75 FR 879 - National Semiconductor Corporation Arlington Manufacturing Site Including On-Site Leased Workers...

Science.gov (United States)

2010-01-06

... engaged in activities related to the production of integrated circuits. The company reports that on-site... Corporation Arlington Manufacturing Site Including On-Site Leased Workers From GCA, CMPA (Silverleaf), Custom..., applicable to workers of National Semiconductor Corporation, Arlington Manufacturing Site, including on-site...

Special Observance Planning Guide

Science.gov (United States)

2015-11-01

Day o Email/broadcast/installation newspaper o Installation marquee/kiosk • Art exhibit • Musical concert • Film festival at installation theater...historical and cultural site visits or staff rides • Cultural dance demonstration • Cultural food festival • Cultural education, training, or...Written invitation to speaker o Musical support (including coordination with the Color Guard) o Audio-visual support and materials for program o PAO

Preparing for Beslan: Anti-Terrorism Recommendations for an American School

Science.gov (United States)

2008-06-13

confronting school -shooter situations. Columbine , Jonesboro, and Virginia Tech are not just places of profound sorrow but rallying cries for those advocating...installed physical security mechanisms to protect students during a school shooting incident. However, to secure students from a concerted terrorist...Strategy Forum 2004, 6). Some Manhattan schools were forced to evacuate to sites miles away. Two high schools ’ evacuation plans called for students to

1994 Site environmental report

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

The Fernald site is a Department of Energy (DOE)-owned facility that produced high-quality uranium metals for military defense for nearly 40 years. DOE suspended production at the site in 1989 and formally ended production in 1991. Although production activities have ceased, the site continues to examine the air and liquid pathways as possible routes through which pollutants from past operations and current remedial activities may leave the site. The Site Environmental Report (SER) is prepared annually in accordance with DOE Order 5400.1, General Environmental Protection Program. This 1994 SER provides the general public as well as scientists and engineers with the results from the site`s ongoing Environmental Monitoring Program. Also included in this report is information concerning the site`s progress toward achieving full compliance with requirements set forth by DOE, U.S. Environmental Protection Agency (USEPA), and Ohio EPA (OEPA). For some readers, the highlights provided in this Executive Summary may provide sufficient information. Many readers, however, may wish to read more detailed descriptions of the information than those which are presented here. All information presented in this summary is discussed more fully in the main body of this report.

Site Specific Ground Response Analysis for Quantifying Site Amplification at A Regolith Site

Directory of Open Access Journals (Sweden)

Bambang Setiawan

2017-08-01

Full Text Available DOI: 10.17014/ijog.4.3.159-167A numerical model has demonstrated that it can simulate reasonably well earthquake motions at the ground level during a seismic event. The most widely used model is an equivalent linear approach. The equivalent linear model was used to compute the free-field response of Adelaide regolith during the 1997 Burra earthquake. The aim of this study is to quantify the amplification at the investigated site. The model computed the ground response of horizontally layered soil deposits subjected to transient and vertically propagating shear waves through a one-dimensional-soil column. Each soil layer was assumed to be homogeneous, visco-elastic, and infinite in the horizontal extent. The results of this study were compared to other studies and forward computation of the geotechnical dynamic parameters of the investigated site. The amplification triggered by the 1997 Burra seismic event was deduced. This study reveals the amplification factor up to 3.6 at the studied site.

A future for nuclear sites beyond their service life. Nuclear site value development; Un avenir pour les sites nucleaires en fin de cycle. Valorisation des sites nucleaires

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

As the nuclear industry moves into a new development phase, many facilities built in the fifties and sixties are reaching the end of their service life. Dismantling them and rehabilitating the sites on which they stand is a major industrial challenge which will give rise to a number of new projects. AREVA has more than 20 years' experience in these highly technical fields. As more and more sites reach the end of their service life, AREVA considers nuclear site value development as a fully-fledged industrial activity. The group's competencies in this field have been grouped together to form a dedicated entity: the Nuclear Site Value Development Business Unit, created in 2008. Several billion euros are invested in site value development projects which are far-reaching and complex, and often last for several decades. Long before work actually begins, lengthy studies and preparations are required to schedule operations, select the techniques to be used and optimize costs and deadlines. The Nuclear Site Value Development BU is currently working on four major projects involving its own facilities and those of the CEA: - La Hague: dismantling of the first generation of used fuel recycling facilities. Between 1966 and 1998, almost 5,000 tons of used fuel from graphite-moderated gas-cooled reactors, 4,500 tons of light water reactor fuel, as well as fuel from fast reactors and research reactors, were treated at UP2 400, the very first industrial recycling plant on the La Hague site. - Marcoule: first-time dismantling of a recycling plant. 1,000 rooms to be cleaned up, 30,000 tons of waste to be treated, 30 years of work. - Cadarache: first-time dismantling of a Mox fuel fabrication plant. The Cadarache plant was commissioned in 1962 to fabricate fuel for fast reactors; this was followed by MOX fuel for light water reactors, an activity which continued until the plant was shut down in 2003. - Annecy and Veurey: giving a new lease of life to former industrial sites

Implementing Site-based Budgeting.

Science.gov (United States)

Sielke, Catherine C.

2001-01-01

Discusses five questions that must be answered before implementing site-based budgeting: Why are we doing this? What budgeting decisions will be devolved to the school site? How do dollars flow from the central office to the site? Who will be involved at the site? How will accountability be achieved? (Author/PKP)

EPA True NO2 ground site measurements – multiple sites, TCEQ ground site measurements of meteorological and air pollution parameters – multiple sites ,GeoTASO NO2 Vertical Column

Data.gov (United States)

U.S. Environmental Protection Agency — EPA True NO2 ground site measurements – multiple sites - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013; TCEQ ground site measurements of...

New Site Coefficients and Site Classification System Used in Recent Building Seismic Code Provisions

Science.gov (United States)

Dobry, R.; Borcherdt, R.D.; Crouse, C.B.; Idriss, I.M.; Joyner, W.B.; Martin, G.R.; Power, M.S.; Rinne, E.E.; Seed, R.B.

2000-01-01

Recent code provisions for buildings and other structures (1994 and 1997 NEHRP Provisions, 1997 UBC) have adopted new site amplification factors and a new procedure for site classification. Two amplitude-dependent site amplification factors are specified: Fa for short periods and Fv for longer periods. Previous codes included only a long period factor S and did not provide for a short period amplification factor. The new site classification system is based on definitions of five site classes in terms of a representative average shear wave velocity to a depth of 30 m (V?? s). This definition permits sites to be classified unambiguously. When the shear wave velocity is not available, other soil properties such as standard penetration resistance or undrained shear strength can be used. The new site classes denoted by letters A - E, replace site classes in previous codes denoted by S1 - S4. Site classes A and B correspond to hard rock and rock, Site Class C corresponds to soft rock and very stiff / very dense soil, and Site Classes D and E correspond to stiff soil and soft soil. A sixth site class, F, is defined for soils requiring site-specific evaluations. Both Fa and Fv are functions of the site class, and also of the level of seismic hazard on rock, defined by parameters such as Aa and Av (1994 NEHRP Provisions), Ss and S1 (1997 NEHRP Provisions) or Z (1997 UBC). The values of Fa and Fv decrease as the seismic hazard on rock increases due to soil nonlinearity. The greatest impact of the new factors Fa and Fv as compared with the old S factors occurs in areas of low-to-medium seismic hazard. This paper summarizes the new site provisions, explains the basis for them, and discusses ongoing studies of site amplification in recent earthquakes that may influence future code developments.

HIGH IMPACT HEAT WAVES OVER THE EURO-MEDITERRANEAN REGION AND TURKEY - IN CONCERT WITH ATMOSPHERIC BLOCKING AND LARGE DYNAMICAL AND PHYSICAL ANOMALIES

Directory of Open Access Journals (Sweden)

Meral Demirtaş

2017-03-01

Full Text Available The increase in high impact heat waves in the Euro-Mediterranean region and Turkey is related to a number of concurring factors that include the persistent anticyclonic weather regimes. The present study investigates the June-July-August (JJA of 2000, 2007 and 2010 heat wave events in concert with some meteorological anomalies (the 500 hPa geopotential height, 850 hPa temperature, sea surface temperature and soil wetness and blocking anticyclones, focusing on heat wave occurrences on a grid point base. Detection methods for atmospheric blocking and heat wave are introduced and applied for the mentioned years. During the 2000 JJA very high temperatures were recorded over the Balkan Peninsula and in Turkey where 42 cities had breaking all time highest temperature records for June, but the duration of heat wave was the shortest. The 2007 summer was also abnormally hot for the region and record breaking temperatures were observed in Greece, Romania, Bulgaria and Turkey where 34 cities had highest temperature records for June and July, and the highest total heat wave duration was 60-70 days. The 2010 JJA period was extremely hot over Russia and nearby countries including Turkey where 9 cities had highest temperature records for August. The 2010 case was marked for; large anomalies, the longest heat wave duration and the highest heat wave intensity. In all cases, heat wave occurrences found to be particularly high over the western part of Turkey. The abnormally hot summers of 2000, 2007 and 2010 could reflect summers to come. The results indicate that summer climate might experience a pronounced increase in year-to-year variability. Increase in variability might be able to explain the high impact heat waves, and would strongly affect their incidence in the future. The results may also contribute to a better understanding of heat waves in context of climate variability.

The site selection process

International Nuclear Information System (INIS)

Kittel, J.H.

1989-01-01

One of the most arduous tasks associated with the management of radioactive wastes is the siting of new disposal facilities. Experience has shown that the performance of the disposal facility during and after disposal operations is critically dependent on the characteristics of the site itself. The site selection process consists of defining needs and objectives, identifying geographic regions of interest, screening and selecting candidate sites, collecting data on the candidate sites, and finally selecting the preferred site. Before the site selection procedures can be implemented, however, a formal legal system must be in place that defines broad objectives and, most importantly, clearly establishes responsibilities and accompanying authorities for the decision-making steps in the procedure. Site selection authorities should make every effort to develop trust and credibility with the public, local officials, and the news media. The responsibilities of supporting agencies must also be spelled out. Finally, a stable funding arrangement must be established so that activities such as data collection can proceed without interruption. Several examples, both international and within the US, are given

Site environmental programs

Energy Technology Data Exchange (ETDEWEB)

Schmidt, J.W.; Hanf, R.W.

1995-06-01

This section of the 1994 Hanford Site Environmental Report summarizes the site environmental programs. Effluent monitoring and environmental surveillance programs monitor for impacts from operations in several areas. The first area consists of the point of possible release into the environment. The second area consists of possible contamination adjacent to DOE facilities, and the third area is the general environment both on and off the site.

Site environmental programs

International Nuclear Information System (INIS)

Schmidt, J.W.; Hanf, R.W.

1995-01-01

This section of the 1994 Hanford Site Environmental Report summarizes the site environmental programs. Effluent monitoring and environmental surveillance programs monitor for impacts from operations in several areas. The first area consists of the point of possible release into the environment. The second area consists of possible contamination adjacent to DOE facilities, and the third area is the general environment both on and off the site

LLNL Experimental Test Site (Site 300) Potable Water System Operations Plan

Energy Technology Data Exchange (ETDEWEB)

Ocampo, R. P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bellah, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2015-09-14

The existing Lawrence Livermore National Laboratory (LLNL) Site 300 drinking water system operation schematic is shown in Figures 1 and 2 below. The sources of water are from two Site 300 wells (Well #18 and Well #20) and San Francisco Public Utilities Commission (SFPUC) Hetch-Hetchy water through the Thomas shaft pumping station. Currently, Well #20 with 300 gallons per minute (gpm) pump capacity is the primary source of well water used during the months of September through July, while Well #18 with 225 gpm pump capacity is the source of well water for the month of August. The well water is chlorinated using sodium hypochlorite to provide required residual chlorine throughout Site 300. Well water chlorination is covered in the Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Chlorination Plan (“the Chlorination Plan”; LLNL-TR-642903; current version dated August 2013). The third source of water is the SFPUC Hetch-Hetchy Water System through the Thomas shaft facility with a 150 gpm pump capacity. At the Thomas shaft station the pumped water is treated through SFPUC-owned and operated ultraviolet (UV) reactor disinfection units on its way to Site 300. The Thomas Shaft Hetch- Hetchy water line is connected to the Site 300 water system through the line common to Well pumps #18 and #20 at valve box #1.

Inter-Site Consistency at a Multi-Site Psychiatry Clerkship

Science.gov (United States)

Shultes von Schlageter, Margo; Park, EunMi; Tucker, Phebe

2006-01-01

Objective: This study examines the effects of clinical site assignment within a multiple-site psychiatry clerkship program on the convergent outcome of the National Board of Medical Examiners (NBME) subject examination. Method: NBME scores, controlled for baseline pre-clerkship knowledge base as measured by second year human behavior scores, were…

NRC staff site characterization analysis of the Department of Energy's Site Characterization Plan, Yucca Mountain Site, Nevada

International Nuclear Information System (INIS)

1989-08-01

This Site Characterization Analysis (SCA) documents the NRC staff's concerns resulting from its review of the US Department of Energy's (DOE's) Site Characterization Plan (SCP) for the Yucca Mountain site in southern Nevada, which is the candidate site selected for characterization as the nation's first geologic repository for high-level radioactive waste. DOE's SCP explains how DOE plans to obtain the information necessary to determine the suitability of the Yucca Mountain site for a repository. NRC's specific objections related to the SCP, and major comments and recommendations on the various parts of DOE's program, are presented in SCA Section 2, Director's Comments and Recommendations. Section 3 contains summaries of the NRC staff's concerns for each specific program, and Section 4 contains NRC staff point papers which set forth in greater detail particular staff concerns regarding DOE's program. Appendix A presents NRC staff evaluations of those NRC staff Consultation Draft SCP concerns that NRC considers resolved on the basis of the SCP. This SCA fulfills NRC's responsibilities with respect to DOE's SCP as specified by the Nuclear Waste Policy Act (NWPA) and 10 CFR 60.18. 192 refs., 2 tabs

Superfund Site Information - Site Sampling Data

Data.gov (United States)

U.S. Environmental Protection Agency — This asset includes Superfund site-specific sampling information including location of samples, types of samples, and analytical chemistry characteristics of...

Effect of crowd size on patient volume at a large, multipurpose, indoor stadium.

Science.gov (United States)

De Lorenzo, R A; Gray, B C; Bennett, P C; Lamparella, V J

1989-01-01

A prediction of patient volume expected at "mass gatherings" is desirable in order to provide optimal on-site emergency medical care. While several methods of predicting patient loads have been suggested, a reliable technique has not been established. This study examines the frequency of medical emergencies at the Syracuse University Carrier Dome, a 50,500-seat indoor stadium. Patient volume and level of care at collegiate basketball and football games as well as rock concerts, over a 7-year period were examined and tabulated. This information was analyzed using simple regression and nonparametric statistical methods to determine level of correlation between crowd size and patient volume. These analyses demonstrated no statistically significant increase in patient volume for increasing crowd size for basketball and football events. There was a small but statistically significant increase in patient volume for increasing crowd size for concerts. A comparison of similar crowd size for each of the three events showed that patient frequency is greatest for concerts and smallest for basketball. The study suggests that crowd size alone has only a minor influence on patient volume at any given event. Structuring medical services based solely on expected crowd size and not considering other influences such as event type and duration may give poor results.

Implementing ‘Site BIM’

DEFF Research Database (Denmark)

Davies, Richard; Harty, Chris

2013-01-01

Numerous Building Information Modelling (BIM) tools are well established and potentially beneficial in certain uses. However, issues of adoption and implementation persist, particularly for on-site use of BIM tools in the construction phase. We describe an empirical case-study of the implementation...... of an innovative ‘Site BIM’ system on a major hospital construction project. The main contractor on the project developed BIM-enabled tools to allow site workers using mobile tablet personal computers to access design information and to capture work quality and progress data on-site. Accounts show that ‘Site BIM...

Olkiluoto site description 2011

International Nuclear Information System (INIS)

2012-12-01

This fourth version of the Olkiluoto Site Report, produced by the OMTF (Olkiluoto Modelling Task Force), updates the Olkiluoto Site Report 2008 with the data and knowledge obtained up to December 2010. A descriptive model of the site (the Site Descriptive Model, SDM), i.e. a model describing the geological and hydrogeological structure of the site, properties of the bedrock and the groundwater and its flow, and the associated interacting processes and mechanisms. The SDM is divided into six parts: surface system, geology, rock mechanics, hydrogeology, hydrogeochemistry and transport properties

Olkiluoto site description 2011

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-12-15

This fourth version of the Olkiluoto Site Report, produced by the OMTF (Olkiluoto Modelling Task Force), updates the Olkiluoto Site Report 2008 with the data and knowledge obtained up to December 2010. A descriptive model of the site (the Site Descriptive Model, SDM), i.e. a model describing the geological and hydrogeological structure of the site, properties of the bedrock and the groundwater and its flow, and the associated interacting processes and mechanisms. The SDM is divided into six parts: surface system, geology, rock mechanics, hydrogeology, hydrogeochemistry and transport properties.

Site Selection for Surplus Plutonium Disposition Facilities at the Savannah River Site

International Nuclear Information System (INIS)

Wike, L.D.

2000-01-01

A site selection study was conducted to evaluate locations for the proposed Surplus Plutonium Disposition Facilities. Facilities to be located include the Mixed Oxide (MOX) Fuel Fabrication Facility, the Pit Disassembly and Conversion Facility (PDCF), and the Plutonium Immobilization Project (PIP) facility. Objectives of the study include: (1) Confirm that the Department of Energy (DOE) selected locations for the MOX and PDCF were suitable based on selected siting criteria, (2) Recommend a site in the vicinity of F Area that is suitable for the PIP, and (3) Identify alternative suitable sites for one or more of these facilities in the event that further geotechnical characterization or other considerations result in disqualification of a currently proposed site

Methods for estimating on-site ambient air concentrations at disposal sites

International Nuclear Information System (INIS)

Hwang, S.T.

1987-01-01

Currently, Gaussian type dispersion modeling and point source approximation are combined to estimate the ambient air concentrations of pollutants dispersed downwind of an areawide emission source, using the approach of virtual point source approximation. This Gaussian dispersion modeling becomes less accurate as the receptor comes closer to the source, and becomes inapplicable for the estimation of on-site ambient air concentrations at disposal sites. Partial differential equations are solved with appropriate boundary conditions for use in estimating the on-site concentrations in the ambient air impacted by emissions from an area source such as land disposal sites. Two variations of solution techniques are presented, and their predictions are compared

Site Rehabilitation Completion Report with No Further Action Proposal for the Northeast Site

Energy Technology Data Exchange (ETDEWEB)

Daniel, Joe [Stoller Newport News Technology, Inc., Grand Junction, CO (United States); Tabor, Charles [Stoller Newport News Technology, Inc., Grand Junction, CO (United States); Survochak, Scott [U.S. Department of Energy, Office of Legacy Management, Grand Junction, CO (United States)

2013-05-01

The purpose of this Site Rehabilitation Completion Report is to present the post-active-remediation monitoring results for the Northeast Site and to propose No Further Action with Controls. This document includes information required by Chapter 62-780.750(4)(d), 62-780.750(6), and 62-780.600(8)(a)27 Florida Administrative Code (F.A.C.). The Closure Monitoring Plan for the Northeast Site and 4.5 Acre Site (DOE 2009a) describes the approach for post-active-remediation monitoring. The Young - Rainey Science, Technology, and Research Center (STAR Center) is a former U.S. Department of Energy (DOE) facility constructed in the mid-1950s. The 99-acre STAR Center is located in Largo, Florida. The Northeast Site is located in the northeast corner of the STAR Center. The Northeast Site meets all the requirements for an RMO II closure—No Further Action with Controls. DOE is nearing completion of a restrictive covenant for the Northeast Site. DOE has completed post-active-remediation monitoring at the Northeast Site as of September 2012. No additional monitoring will be conducted.

Expedited Site Characterization: A rapid, cost-effective process for preremedial site characterization

International Nuclear Information System (INIS)

Burton, J.C.; Walker, J.L.; Jennings, T.V.; Aggarwal, P.K.; Hastings, B.; Meyer, W.T.; Rose, C.M.; Rosignolo, C.L.

1993-01-01

Argonne National Laboratory has developed a unique, cost- and time-effective, technically innovative process for preremedial site characterization, referred to as Expedited Site Characterization (ESC). The cost of the ESC field sampling process ranges from 1/10 to 1/5 of the cost of traditional site characterization. The time required for this ESC field activity is approximately 1/30 of that for current methods. Argonne's preremedial site investigations based on this approach have been accepted by the appropriate regulatory agencies. The ESC process is flexible and neither site nor contaminant dependent. The process has been successfully tested and applied in site investigations of multiple contaminated landfills in New Mexico (for the US Department of the Interior's Bureau of Land Management [BLM]) and at former grain storage facilities in Nebraska and Kansas, contaminated with carbon tetrachloride (for the Department of Agriculture's Commodity Credit Corporation [CCC/USDA]). A working demonstration of this process was sponsored by the US Department of Energy (DOE) Office of Technology Development as a model of the methodology needed to accelerate site characterizations at DOE facilities. This report describes the application of the process in New Mexico, Nebraska and Kansas

Site observational work plan for the UMTRA project site at Grand Junction, Colorado

International Nuclear Information System (INIS)

1996-01-01

This site observational work plan (SOWP) is one of the first Uranium Mill Tailings Remedial Action (UMTRA) Ground Water Project documents developed to select a compliance strategy that meets the UMTRA ground water standards for the Grand Junction site. This SOWP applies information about the Grand Junction site to the compliance strategy selection framework developed in the UMTRA Ground Water Project draft programmatic environmental impact statement. This risk-based, decision-making framework identifies the decision logic for selecting compliance strategies that could be used to meet the ground water standards. The US Department of Energy (DOE) goal is to implement a cost-effective site strategy that complies with the ground water standards and protects human health and the environment. Based on an evaluation of the site characterization and risk assessment data available for the preparation of this SOWP, DOE proposes that the most likely compliance strategy for the Grand Junction site is no remediation with the application of supplemental standards. This proposed strategy is based on a conceptual site model that indicates site-related contamination is confined to a limited-use aquifer as defined in the ground water standards. The conceptual model demonstrates that the uranium processing-related contamination at the site has affected the unconfined alluvial aquifer, but not the deeper confined aquifer

Searching your site`s management information systems

Energy Technology Data Exchange (ETDEWEB)

Marquez, W.; Rollin, C. [S.M. Stoller Corp., Boulder, CO (United States)

1994-12-31

The Department of Energy`s guidelines for the Baseline Environmental Management Report (BEMR) encourage the use of existing data when compiling information. Specific systems mentioned include the Progress Tracking System, the Mixed-Waste Inventory Report, the Waste Management Information System, DOE 4700.1-related systems, Programmatic Environmental Impact Statement (PEIS) data, and existing Work Breakdown Structures. In addition to these DOE-Headquarters tracking and reporting systems, there are a number of site systems that will be relied upon to produce the BEMR, including: (1) site management control and cost tracking systems; (2) commitment/issues tracking systems; (3) program-specific internal tracking systems; (4) Site material/equipment inventory systems. New requirements have often prompted the creation of new, customized tracking systems. This is a very time and money consuming process. As the BEMR Management Plan emphasizes, an effort should be made to use the information in existing tracking systems. Because of the wealth of information currently available from in-place systems, development of a new tracking system should be a last resort.

Application of the Integrated Site and Environment Data Management System for LILW Disposal Site

International Nuclear Information System (INIS)

Lee, Ji Hoon; Lee, Eun Yong; Kim, Chang Lak

2007-01-01

During the last five years, Site Information and Total Environmental data management System(SITES) has been developed. SITES is an integrated program for overall data acquisition, environmental monitoring, and safety analysis. SITES is composed of three main modules, such as site database system (SECURE), safety assessment system (SAINT) and environmental monitoring system (SUDAL). In general, for the safe management of radioactive waste repository, the information of site environment should be collected and managed systematically from the initial site survey. For this, SECURE module manages its data for the site characterization, environmental information, and radioactive environmental information etc. The purpose of SAINT module is to apply and analyze the data from SECURE. SUDAL is developed for environmental monitoring of the radioactive waste repository. Separately, it is ready to open to the public for offering partial information

Nevada Test Site Environmental Report 2009, Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills, ed.

2010-09-13

This attachment expands on the general description of the Nevada Test Site (NTS) presented in the Introduction to the Nevada Test Site Environmental Report 2009. Included are subsections that summarize the site’s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site’s environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Ocean Disposal Site Monitoring

Science.gov (United States)

EPA is responsible for managing all designated ocean disposal sites. Surveys are conducted to identify appropriate locations for ocean disposal sites and to monitor the impacts of regulated dumping at the disposal sites.

Site characterization criteria (DOE-STD-1022-94) for natural phenomena hazards at DOE sites

International Nuclear Information System (INIS)

Chen, J.C.; Ueng, T.S.; Boissonnade, A.C.

1995-12-01

This paper briefly summarizes requirements of site characterization for Natural Phenomena Hazards (NPH) at DOE sites. In order to comply with DOE Order 5480.28, site characterization criteria has been developed to provide site-specific information needed for development of NPH assessment criteria. Appropriate approaches are outlined to ensure that the current state-of-the-art methodologies and procedures are used in the site characterization. General and detailed site characterization requirements are provided in the areas of meteorology, hydrology, geology, seismology and geotechnical studies

Non-Invasive Seismic Methods for Earthquake Site Classification Applied to Ontario Bridge Sites

Science.gov (United States)

Bilson Darko, A.; Molnar, S.; Sadrekarimi, A.

2017-12-01

How a site responds to earthquake shaking and its corresponding damage is largely influenced by the underlying ground conditions through which it propagates. The effects of site conditions on propagating seismic waves can be predicted from measurements of the shear wave velocity (Vs) of the soil layer(s) and the impedance ratio between bedrock and soil. Currently the seismic design of new buildings and bridges (2015 Canadian building and bridge codes) requires determination of the time-averaged shear-wave velocity of the upper 30 metres (Vs30) of a given site. In this study, two in situ Vs profiling methods; Multichannel Analysis of Surface Waves (MASW) and Ambient Vibration Array (AVA) methods are used to determine Vs30 at chosen bridge sites in Ontario, Canada. Both active-source (MASW) and passive-source (AVA) surface wave methods are used at each bridge site to obtain Rayleigh-wave phase velocities over a wide frequency bandwidth. The dispersion curve is jointly inverted with each site's amplification function (microtremor horizontal-to-vertical spectral ratio) to obtain shear-wave velocity profile(s). We apply our non-invasive testing at three major infrastructure projects, e.g., five bridge sites along the Rt. Hon. Herb Gray Parkway in Windsor, Ontario. Our non-invasive testing is co-located with previous invasive testing, including Standard Penetration Test (SPT), Cone Penetration Test and downhole Vs data. Correlations between SPT blowcount and Vs are developed for the different soil types sampled at our Ontario bridge sites. A robust earthquake site classification procedure (reliable Vs30 estimates) for bridge sites across Ontario is evaluated from available combinations of invasive and non-invasive site characterization methods.

DOE site performance assessment activities

International Nuclear Information System (INIS)

1990-07-01

Information on performance assessment capabilities and activities was collected from eight DOE sites. All eight sites either currently dispose of low-level radioactive waste (LLW) or plan to dispose of LLW in the near future. A survey questionnaire was developed and sent to key individuals involved in DOE Order 5820.2A performance assessment activities at each site. The sites surveyed included: Hanford Site (Hanford), Idaho National Engineering Laboratory (INEL), Los Alamos National Laboratory (LANL), Nevada Test Site (NTS), Oak Ridge National Laboratory (ORNL), Paducah Gaseous Diffusion Plant (Paducah), Portsmouth Gaseous Diffusion Plant (Portsmouth), and Savannah River Site (SRS). The questionnaire addressed all aspects of the performance assessment process; from waste source term to dose conversion factors. This report presents the information developed from the site questionnaire and provides a comparison of site-specific performance assessment approaches, data needs, and ongoing and planned activities. All sites are engaged in completing the radioactive waste disposal facility performance assessment required by DOE Order 5820.2A. Each site has achieved various degrees of progress and have identified a set of critical needs. Within several areas, however, the sites identified common needs and questions

Nevada Test Site Environmental Report 2006 and Site Description (Volume 1)

Energy Technology Data Exchange (ETDEWEB)

Cathy Wills

2007-10-01

The Nevada Test Site Environmental Report 2006 (NTSER) was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec). This Executive Summary presents the purpose of the document, the major programs conducted at the Nevada Test Site (NTS), NTS key environmental initiatives, radiological releases and potential doses to the public resulting from site operations, a summary of nonradiological releases, implementation status of the NTS Environmental Management System, a summary of compliance with environmental regulations, pollution prevention and waste minimization accomplishments, and significant environmental accomplishments. Much of the content of this Executive Summary is also presented in a separate stand-alone pamphlet titled Nevada Test Site Environmental Report Summary 2006 produced to be a more cost-effective means of distributing information contained in the NTSER to interested DOE stakeholders.

Site selection - siting of the final repository for spent nuclear fuel

International Nuclear Information System (INIS)

2011-03-01

SKB has selected Forsmark as the site for the final repository for spent nuclear fuel. The site selection is the end result of an extensive siting process that began in the early 1990s. The strategy and plan for the work was based on experience from investigations and development work over a period of more than ten years prior to then. This document describes the siting work and SKB's choice of site for the final repository. It also presents the information on which the choice was based and the reasons for the decisions made along the way. The document comprises Appendix PV to applications under the Nuclear Activities Act and the Environmental Code for licences to build and operate an encapsulation plant adjacent to the central interim storage facility for spent nuclear fuel in Oskarshamn, and to build and operate a final repository for spent nuclear fuel in Forsmark in Oesthammar Municipality

Site selection - siting of the final repository for spent nuclear fuel

Energy Technology Data Exchange (ETDEWEB)

2011-03-15

SKB has selected Forsmark as the site for the final repository for spent nuclear fuel. The site selection is the end result of an extensive siting process that began in the early 1990s. The strategy and plan for the work was based on experience from investigations and development work over a period of more than ten years prior to then. This document describes the siting work and SKB's choice of site for the final repository. It also presents the information on which the choice was based and the reasons for the decisions made along the way. The document comprises Appendix PV to applications under the Nuclear Activities Act and the Environmental Code for licences to build and operate an encapsulation plant adjacent to the central interim storage facility for spent nuclear fuel in Oskarshamn, and to build and operate a final repository for spent nuclear fuel in Forsmark in Oesthammar Municipality

Nevada Test Site Environmental Report 2006 and Site Description (Volume 1)

International Nuclear Information System (INIS)

Cathy Wills

2007-01-01

The Nevada Test Site Environmental Report 2006 (NTSER) was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec). This Executive Summary presents the purpose of the document, the major programs conducted at the Nevada Test Site (NTS), NTS key environmental initiatives, radiological releases and potential doses to the public resulting from site operations, a summary of nonradiological releases, implementation status of the NTS Environmental Management System, a summary of compliance with environmental regulations, pollution prevention and waste minimization accomplishments, and significant environmental accomplishments. Much of the content of this Executive Summary is also presented in a separate stand-alone pamphlet titled Nevada Test Site Environmental Report Summary 2006 produced to be a more cost-effective means of distributing information contained in the NTSER to interested DOE stakeholders

Site observational work plan for the UMTRA Project site at Falls City, Texas

International Nuclear Information System (INIS)

1995-06-01

Produced by the US Department of Energy (DOE), this site observational work plan (SOWP) will be used to determine site-specific activities to comply with the US Environmental Protection Agency (EPA) ground water standards at this Uranium Mill Tailings Remedial Action (UMTRA) Project site. The purpose of the SOWP is to recommend a site-specific ground water compliance strategy at the Falls City UMTRA Project site. The Falls City SOWP presents a comprehensive summary of site hydrogeological data, delineates a conceptual model of the aquifer system, and discusses the origins of milling-related ground water contamination. It also defines the magnitude of ground water contamination, potential environmental and health risks associated with ground water contamination and data gaps, and targets a proposed compliance strategy

Site-Specific Seismic Site Response Model for the Waste Treatment Plant, Hanford, Washington

Energy Technology Data Exchange (ETDEWEB)

Rohay, Alan C.; Reidel, Steve P.

2005-02-24

This interim report documents the collection of site-specific geologic and geophysical data characterizing the Waste Treatment Plant site and the modeling of the site-specific structure response to earthquake ground motions.

Technical know-how of site descriptive modeling for site characterization - 59089

International Nuclear Information System (INIS)

Saegusa, Hiromitsu; Onoe, Hironori; Doke, Ryosuke; Niizato, Tadafumi; Yasue, Ken-ichi

2012-01-01

The site descriptive model covering the current status of characteristics of geological environment and the site evolution model for estimation of the long-term evolution of site conditions are used to integrate multi-disciplinary investigation results. It is important to evaluate uncertainties in the models, to specify issues regarding the uncertainties and to prioritize the resolution of specified issues, for the planning of site characterization. There is a large quantity of technical know-how in the modeling process. It is important to record the technical know-how with transparency and traceability, since site characterization projects generally need long duration. The transfer of the technical know-how accumulated in the research and development (R and D) phase to the implementation phase is equally important. The aim of this study is to support the planning of initial surface-based site characterizations based on the technical know-how accumulated from the underground research laboratory projects. These projects are broad scientific studies of the deep geological environment and provide a technical basis for the geological disposal of high-level radioactive wastes. In this study, a comprehensive task flow from acquisition of existing data to planning of field investigations through the modeling has been specified. Specific task flow and decision-making process to perform the tasks have been specified. (authors)

Site observational work plan for the UMTRA Project Site at Grand Junction, Colorado

International Nuclear Information System (INIS)

1996-03-01

The U.S. Department of Energy (DOE) has prepared this initial site observational work plan (SOWP) for the Uranium Mill Tailings Remedial Action (UMTRA) Project site in Grand Junction, Colorado. This SOWP is one of the first UMTRA Ground Water Project documents developed to select a compliance strategy that meets the UMTRA ground water standards (40 CFR Part 192, as amended by 60 FR 2854) for the Grand Junction site. This SOWP applies information about the Grand Junction site to the compliance strategy selection framework developed in the UMTRA Ground Water Project draft programmatic environmental impact statement (PEIS). This risk-based, decision-making framework identifies the decision logic for selecting compliance strategies that could be used to meet the ground water standards. The DOE goal is to use the observational method to implement a cost-effective site strategy that complies with the ground water standards and protects human health and the environment. Based on an evaluation of the site characterization and risk assessment data available for the preparation of this SOWP, DOE proposes that the most likely compliance strategy for the Grand Junction site is no remediation based on the application of supplemental standards. This proposed strategy is based on a conceptual site model that indicates site-related contamination is confined to a limited-use aquifer as defined in the ground water standards

Site enforcement tracking system (SETS): PRP listing by site for region 9

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 8

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 10

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 3

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 2

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 5

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

Site enforcement tracking system (SETS): PRP listing by site for region 6

International Nuclear Information System (INIS)

1993-04-01

When expending Superfund monies at a CERCLA (Comprehensive Environmental Response, Compensation and Liability Act) site, EPA must conduct a search to identify parties with potential financial responsibility for remediation of uncontrolled hazardous waste sites. EPA regional Superfund Waste Management Staff issue a notice letter to the potentially responsible party (PRP). Data from the notice letter is used to form the Site Enforcement Tracking System (SETS). The data includes PRP name and address, a company contact person, the date the notice was issued, and the related CERCLA site name and identification number

MAQUETTE ORL Décembre 2004

African Journals Online (AJOL)

3 : Actine musculaire lisse(+). Cet examen concluait au diagnostic de fasciite nodulaire. Une exérèse de la tumeur fut alors programmée. Elle fut menée sous anesthésie générale, par voie endobuccale avec section autour du pédicule en muqueuse saine. (Figure 4). Fig. 4 : Pièce opératoire. Les suites opératoires furent ...

Women's Household Environmental Caring Roles in the Greater ...

African Journals Online (AJOL)

Le résultat d'un sondage qualitatif mené à Accra montre que les problèmes liés à l'environnement autour des maisons posent des problèmes sanitaires extrêmement serieux aux femmes et aux enfants. Ces problèmes sont aggravés par la pauvreté. Cette situation demande que l'on se prenne sérieusement aux débats et ...

78 Rôle hydrogéologique des linéaments structuraux en milieu ...

African Journals Online (AJOL)

TEDDY

Recherche des Sciences de la Terre et des Ressources Minières, (UFR- STRM) Université ... géométriques des blocs et des débits des forages a permis de mettre en évidence le rôle hydrogéologique .... d'altitude moyenne égale à 200 m et inclinée vers la mer au sud avec une pente moyenne autour de 2 %. Le.

Nuclear site selection studies

International Nuclear Information System (INIS)

Gharib, A.; Zohoorian Izadpanah, A.A.; Iranmanesh, H.

2000-01-01

It is of special importance, especially from the nuclear safety viewpoint, to select suitable sites for different nuclear structures with the considered future activities. Site selection sometimes involves high costs not necessarily for merely selecting of site but for some preliminary measures to be taken so as the site may have the necessary characteristics. The more suitable the natural characteristics of the site for the considered project, the more successful and efficient the project, the lower the project costs and the longer the project operation period. If so, the project will cause the growth of public culture and sustainable socioeconomic development. This paper is the result of the conclusion of numerous massive reports of this activity in the preliminary phase based on theories, practices and the related safety principles on this ground as well as the application of data and information of the past and a glance to the future. The conception of need for a site for medium structures and nuclear research projects and how to perform this process are presented step by step here with a scientific approach to its selection during the investigations. In this study, it is practically described how the site is selected, by determining and defining the characteristics of research and nuclear projects with medium structures and also its fitting to the optimum site. The discovered sites typically involve the best advantages in technical and economic aspects and no particular contrast with the concerned structures

Promoting Your Web Site.

Science.gov (United States)

Raeder, Aggi

1997-01-01

Discussion of ways to promote sites on the World Wide Web focuses on how search engines work and how they retrieve and identify sites. Appropriate Web links for submitting new sites and for Internet marketing are included. (LRW)

Site selection handbook: Workshop on site selection for low-level radioactive waste disposal facilities

International Nuclear Information System (INIS)

1987-10-01

The Low-Level Radioactive Waste Policy Amendments Act of 1985 (LLRWPAA) requires the Department of Energy (DOE) to provide technical assistance to ''...those compact regions, host States and nonmember States determined by the Secretary to require assistance.'' Technical assistance has been defined to include, but not be limited to, ''technical guidelines for site selection.'' This site selection workshop was developed to assist States and Compacts in developing new low-level radioactive waste (LLW) disposal sites in accordance with the requirements of the LLRWPAA. The workshop comprises a series of lectures, discussion topics, and exercises, supported by this Site Selection Workshop Handbook, designed to examine various aspects of a comprehensive site selection program. It is not an exhaustive treatment of all aspects of site selection, nor is it prescriptive. The workshop focuses on the major elements of site selection and the tools that can be used to implement the site selection program

The voluntary siting process: The solution to siting in the Northeast Compact

International Nuclear Information System (INIS)

Deshais, J.B.

1995-01-01

The date: June 10, 1991. The decision: the announcement of three 'candidate sites' for a low-level radioactive waste (LLRW) facility in Connecticut following statewide screening. The debate: the right of the citizens of the state to refuse to have this type of facility in their 'backyard' versus the State's responsibility to provide for the safe management of LLRW generated within its borders. The debacle: vigorous opposition, political involvement, no opportunity for effective dialogue with the candidate towns. The end: a legislative mandate to terminate the siting process. This series of events, familiar to those in the business of attempting to site and develop unwanted and unwelcome facilities, would have thwarted efforts to provide for disposal capacity in the Northeast Compact region. Connecticut's efforts to site a LLRW disposal facility pursuant to a traditional 'decide-announce-defend' approach had apparently failed. New Jersey, its partner in the Compact, was also ready to proceed with a similar process that would lead to the naming of several candidate sites, but suspended its efforts to review other siting alternatives. The problem: a new approach was needed. The answer: both states would pursue voluntary siting for the LLRW facilities. The result: the best chance for successful development of LLRW disposal capacity in the Northeast Compact region

Site Selection for the Salt Disposition Facility at the Savannah River Site

International Nuclear Information System (INIS)

Gladden, J.B.; Rueter, K.J.; Morin, J.P.

2000-01-01

A site selection study was conducted to identify a suitable location for the construction and operation of a new Salt Disposition Facility (SDF) at the Savannah River Site (SRS). The facility to be sited is a single processing facility and support buildings that could house either of three technology alternatives being developed by the High Level Waste Systems Engineering Team: Small Tank Tetraphenylborate Precipitation, Crystalline Silicotitanate Non-Elutable Ion Exchange or Caustic Side Solvent Extraction. A fourth alternative, Direct Disposal in grout, is not part of the site selection study because a location has been identified that is unique to this technology (i.e., Z-Area). Facility site selection at SRS is a formal, documented process that seeks to optimize siting of new facilities with respect to facility-specific engineering requirements, sensitive environmental resources, and applicable regulatory requirements. In this manner, the prime objectives of cost minimization, environmental protection, and regulatory compliance are achieved. The results from this geotechnical characterization indicated that continued consideration be given to Site B for the proposed SDF. Suitable topography, the lack of surface hydrology and floodplain issues, no significant groundwater contamination, the presence of minor soft zones along the northeast portion of footprint, and no apparent geological structure in the Gordon Aquitard support this recommendation

Facility siting as a decision process at the Savannah River Site

International Nuclear Information System (INIS)

Wike, L.D.

1995-01-01

Site selection for new facilities at Savannah River Site (SRS) historically has been a process dependent only upon specific requirements of the facility. While this approach is normally well suited to engineering and operational concerns, it can have serious deficiencies in the modern era of regulatory oversight and compliance requirements. There are many issues related to the site selection for a facility that are not directly related to engineering or operational requirements; such environmental concerns can cause large schedule delays and budget impact,s thereby slowing or stopping the progress of a project. Some of the many concerns in locating a facility include: waste site avoidance, National Environmental Policy Act requirements, Clean Water Act, Clean Air Act, wetlands conservation, US Army Corps of Engineers considerations, US Fish and Wildlife Service statutes including threatened and endangered species issues, and State of South Carolina regulations, especially those of the Department of Health and Environmental Control. In addition, there are SRS restrictions on research areas set aside for National Environmental Research Park (NERP), Savannah River Ecology Laboratory, Savannah River Forest Station, University of South Carolina Institute of Archaeology and Anthropology, Southeastern Forest Experimental Station, and Savannah River Technology Center (SRTC) programs. As with facility operational needs, all of these siting considerations do not have equal importance. The purpose of this document is to review recent site selection exercises conducted for a variety of proposed facilities, develop the logic and basis for the methods employed, and standardize the process and terminology for future site selection efforts

Site Environmental Report, 1993

Energy Technology Data Exchange (ETDEWEB)

1994-06-01

The Site Environmental Report (SER) is prepared annually in accordance with DOE Order 5400.1, ``General Environmental Protection Program.`` This 1993 SER provides the general public as well as scientists and engineers with the results from the site`s ongoing Environmental Monitoring Program. Also included in this report is information concerning the site`s progress toward achieving full compliance with requirements set forth by DOE, US Environmental Protection Agency (USEPA), and Ohio EPA (OEPA). For some readers, the highlights provided in the Executive Summary may provide sufficient information. Many readers, however, may wish to read more detailed descriptions of the information than those which are presented here.

Duplication and concerted evolution of MiSp-encoding genes underlie the material properties of minor ampullate silks of cobweb weaving spiders.

Science.gov (United States)

Vienneau-Hathaway, Jannelle M; Brassfield, Elizabeth R; Lane, Amanda Kelly; Collin, Matthew A; Correa-Garhwal, Sandra M; Clarke, Thomas H; Schwager, Evelyn E; Garb, Jessica E; Hayashi, Cheryl Y; Ayoub, Nadia A

2017-03-14

Orb-web weaving spiders and their relatives use multiple types of task-specific silks. The majority of spider silk studies have focused on the ultra-tough dragline silk synthesized in major ampullate glands, but other silk types have impressive material properties. For instance, minor ampullate silks of orb-web weaving spiders are as tough as draglines, due to their higher extensibility despite lower strength. Differences in material properties between silk types result from differences in their component proteins, particularly members of the spidroin (spider fibroin) gene family. However, the extent to which variation in material properties within a single silk type can be explained by variation in spidroin sequences is unknown. Here, we compare the minor ampullate spidroins (MiSp) of orb-weavers and cobweb weavers. Orb-web weavers use minor ampullate silk to form the auxiliary spiral of the orb-web while cobweb weavers use it to wrap prey, suggesting that selection pressures on minor ampullate spidroins (MiSp) may differ between the two groups. We report complete or nearly complete MiSp sequences from five cobweb weaving spider species and measure material properties of minor ampullate silks in a subset of these species. We also compare MiSp sequences and silk properties of our cobweb weavers to published data for orb-web weavers. We demonstrate that all our cobweb weavers possess multiple MiSp loci and that one locus is more highly expressed in at least two species. We also find that the proportion of β-spiral-forming amino acid motifs in MiSp positively correlates with minor ampullate silk extensibility across orb-web and cobweb weavers. MiSp sequences vary dramatically within and among spider species, and have likely been subject to multiple rounds of gene duplication and concerted evolution, which have contributed to the diverse material properties of minor ampullate silks. Our sequences also provide templates for recombinant silk proteins with tailored

Particle Physics Education Sites

Science.gov (United States)

back to home page Particle Physics Education Sites quick reference Education and Information - National Laboratory Education Programs - Women and Minorities in Physics - Other Physics Sites - Physics Alliance - Accelerators at National Laboratories icon Particle Physics Education and Information sites: top

Site Area Boundaries

Data.gov (United States)

U.S. Environmental Protection Agency — This dataset consists of site boundaries from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times and...

Description of the Northwest hazardous waste site data base and preliminary analysis of site characteristics

International Nuclear Information System (INIS)

Woodruff, D.L.; Hartz, K.E.; Triplett, M.B.

1988-08-01

The Northwest Hazardous Waste RD and D Center (the Center) conducts research, development, and demonstration (RD and D) activities for hazardous and radioactive mixed-waste technologies applicable to remediating sites in the states of Idaho, Montana, Oregon, and Washington. To properly set priorities for these RD and D activities and to target development efforts it is necessary to understand the nature of the sites requiring remediation. A data base of hazardous waste site characteristics has been constructed to facilitate this analysis. The data base used data from EPA's Region X Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) and from Preliminary Assessment/Site Investigation (PA/SI) forms for sites in Montana. The Center's data base focuses on two sets of sites--those on the National Priorities List (NPL) and other sites that are denoted as ''active'' CERCLIS sites. Active CERCLIS sites are those sites that are undergoing active investigation and analysis. The data base contains information for each site covering site identification and location, type of industry associated with the site, waste categories present (e.g., heavy metals, pesticides, etc.), methods of disposal (e.g., tanks, drums, land, etc.), waste forms (e.g., liquid, solid, etc.), and hazard targets (e.g., surface water, groundwater, etc.). As part of this analysis, the Northwest region was divided into three geographic subregions to identify differences in disposal site characteristics within the Northwest. 2 refs., 18 figs., 5 tabs

Nevada Test Site Environmental Report 2008 Attachment A: Site Description

Energy Technology Data Exchange (ETDEWEB)

Cathy A. Wills

2009-09-01

This attachment expands on the general description of the Nevada Test Site (NTS) presented in the Introduction to the Nevada Test Site Environmental Report 2008 (National Security Technologies, LLC [NSTec], 2009a). Included are subsections that summarize the site’s geological, hydrological, climatological, and ecological setting. The cultural resources of the NTS are also presented. The subsections are meant to aid the reader in understanding the complex physical and biological environment of the NTS. An adequate knowledge of the site’s environment is necessary to assess the environmental impacts of new projects, design and implement environmental monitoring activities for current site operations, and assess the impacts of site operations on the public residing in the vicinity of the NTS. The NTS environment contributes to several key features of the site that afford protection to the inhabitants of adjacent areas from potential exposure to radioactivity or other contaminants resulting from NTS operations. These key features include the general remote location of the NTS, restricted access, extended wind transport times, the great depths to slow-moving groundwater, little or no surface water, and low population density. This attachment complements the annual summary of monitoring program activities and dose assessments presented in the main body of this report.

Subsurface characterization and geohydrologic site evaluation West Chestnut Ridge site

International Nuclear Information System (INIS)

1984-01-01

The West Chestnut Ridge Site at the Oak Ridge National Laboratory is being considered for use as a repository for low-level radioactive waste. The purposes of this study were to provide a geohydrological characterization of the site for use in pathways analysis, and to provide preliminary geotechnical recommendations that would be used for development of a site utilization plan. Subsurface conditions were investigated at twenty locations and observation wells were installed. Field testing at each location included the Standard Penetration Test and permeability tests in soil and rock. A well pumping test was ocmpleted at one site. Laboratory testing included permeability, deformability, strength and compaction tests, as well as index and physical property tests. The field investigations showed that the subsurface conditions include residual soil overlying a weathered zone of dolomite which grades into relatively unweathered dolomite at depth. The thickness of residual soil is typically 80 ft (24 m) on the ridges, but can be as little as 10 ft (3 m) in the valleys. Trench excavations to depths of 30 ft (9 m) should not present serious slope stability problems above the water table. On-site soils can be used for liners or trench backfill but these soils may require moisture conditioning to achieve required densities. 19 figures, 8 tables

A novel Meloidogyne graminicola effector, MgGPP, is secreted into host cells and undergoes glycosylation in concert with proteolysis to suppress plant defenses and promote parasitism.

Directory of Open Access Journals (Sweden)

Jiansong Chen

2017-04-01

Full Text Available Plant pathogen effectors can recruit the host post-translational machinery to mediate their post-translational modification (PTM and regulate their activity to facilitate parasitism, but few studies have focused on this phenomenon in the field of plant-parasitic nematodes. In this study, we show that the plant-parasitic nematode Meloidogyne graminicola has evolved a novel effector, MgGPP, that is exclusively expressed within the nematode subventral esophageal gland cells and up-regulated in the early parasitic stage of M. graminicola. The effector MgGPP plays a role in nematode parasitism. Transgenic rice lines expressing MgGPP become significantly more susceptible to M. graminicola infection than wild-type control plants, and conversely, in planta, the silencing of MgGPP through RNAi technology substantially increases the resistance of rice to M. graminicola. Significantly, we show that MgGPP is secreted into host plants and targeted to the ER, where the N-glycosylation and C-terminal proteolysis of MgGPP occur. C-terminal proteolysis promotes MgGPP to leave the ER, after which it is transported to the nucleus. In addition, N-glycosylation of MgGPP is required for suppressing the host response. The research data provide an intriguing example of in planta glycosylation in concert with proteolysis of a pathogen effector, which depict a novel mechanism by which parasitic nematodes could subjugate plant immunity and promote parasitism and may present a promising target for developing new strategies against nematode infections.