WorldWideScience

Sample records for site integrator operable

  1. AN/FSY-3 Space Fence System – Sensor Site One/Operations Center Integration Status and Sensor Site Two Planned Capability

    Science.gov (United States)

    Fonder, G. P.; Hack, P. J.; Hughes, M. R.

    This paper covers two topics related to Space Fence System development: Sensor Site One / Operations Center construction and integration status including risk reduction integration and test efforts at the Moorestown, NJ Integrated Test Bed (ITB); and the planned capability of Sensor Site Two. The AN/FSY-3 Space Fence System is a ground-based system of S-band radars integrated with an Operations Center designed to greatly enhance the Air Force Space Surveillance network. The radar architecture is based on Digital Beam-forming. This capability permits tremendous user-defined flexibility to customize volume surveillance and track sectors instantaneously without impacting routine surveillance functions. Space Fence provides unprecedented sensitivity, coverage and tracking accuracy, and contributes to key mission threads with the ability to detect, track and catalog small objects in LEO, MEO and GEO. The system is net-centric and will seamlessly integrate into the existing Space Surveillance Network, providing services to external users—such as JSpOC—and coordinating handoffs to other SSN sites. Sensor Site One construction on the Kwajalein Atoll is in progress and nearing completion. The Operations Center in Huntsville, Alabama has been configured and will be integrated with Sensor Site One in the coming months. System hardware, firmware, and software is undergoing integration testing at the Mooretown, NJ ITB and will be deployed at Sensor Site One and the Operations Center. The preliminary design for Sensor Site Two is complete and will provide critical coverage, timeliness, and operational flexibility to the overall system.

  2. CERCLA integration with site operations the Fernald experience

    International Nuclear Information System (INIS)

    Coyle, S.W.; Shirley, R.S.; Varchol, B.D.

    1991-01-01

    A major transition in the Fernald Environmental Management Project (FEMP) site mission has occurred over the past few years. The production capabilities formally provided by the FEMP are being transferred to private industry through a vendor qualification program. Environmental compliance and site cleanup are now the primary focus. In line with this program, the production of uranium products at the site was suspended in July 1989 in order to concentrate resources on the environmental mission. Formal termination of the FEMP production mission was accomplished on June 19, 1991. Environmental issues such as stored inventories of process residues materials and equipment are being addressed under the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA). The diversity of these hazards complicates the strategic planning for an integrated site cleanup program. The FEMP is one of the first Department of Energy (DOE) facilities to transition from an active production mission guided by Defense Programs (DP) to an environmental mission guided by Environmental Management (EM) under Leo Duffy. Westinghouse Environmental Management Company of Ohio (WEMCO) has been charged with integrating all site activities to carry out the cleanup. A new management structure has been formulated, and an integration approach initiated. Analyses are under way to evaluate all site activities such as waste management, safe shutdown, product material disposition and routine environmental monitoring in view of CERCLA requirements. Site activities are being broken down into three categories: (a) CERCLA driven - restoration work required under CERCLA, (b) CERCLA covered - other environmental requirements which must be integrated with CERCLA, and (c) CERCLA exempt (if any). The approach to comply with these categorized activities must be negotiated with state and federal regulatory agencies

  3. CERCLA integration with site operations the Fernald experience

    International Nuclear Information System (INIS)

    Coyle, S.W.; Shirley, R.S.; Varchol, B.D.

    1991-01-01

    A major transition in the Fernald Environmental Management Project (FEMP) site mission has occurred over the past few years. The production capabilities formally provided by the FEMP are being transferred to private industry through a vendor qualification program. Environmental compliance and site cleanup are now the primary focus. In line with this program, the production of uranium products at the site was suspended in July 1989 in order to concentrate resources on the environmental mission. Formal termination of the FEMP production mission was accomplished on June 19, 1991. Environmental issues such as stored inventories of process residues materials and equipment are being addressed under the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA). The diversity of these hazards complicates the strategic planning for an integrated site cleanup program. This paper will discuss the programmatic approach which is being implemented to ensure activities such as waste management, site utility and support services, health and safety programs, and Resource Conservation and Recovery Act (RCRA) programs are being integrated with CERCLA. 6 figs., 3 tabs

  4. BIOTIC INTEGRITY OF STREAMS IN THE SAVANNAH RIVER SITE INTEGRATOR OPERABLE UNITS, 1996 TO 2003

    Energy Technology Data Exchange (ETDEWEB)

    Paller, M; Susan Dyer, S

    2004-11-08

    The Savannah River Site (SRS) has been divided into six Integrator Operable Units (IOUs) that correspond to the watersheds of the five major streams on the SRS (Upper Three Runs, Fourmile Branch, Pen Branch, Steel Creek, and Lower Three Runs) and the portions of the Savannah River and Savannah River Swamp associated with the SRS. The streams are the primary integrators within each IOU because they potentially receive, through surface or subsurface drainage, soluble contaminants from all waste sites within their watersheds. If these contaminants reach biologically significant levels, they would be expected to effect the numbers, types, and health of stream organisms. In this study, biological sampling was conducted within each IOU as a measure of the cumulative ecological effects of the waste sites within the IOUs. The use of information from biological sampling to assess environmental quality is often termed bioassessment. The IOU bioassessment program included 38 sites in SRS streams and nine sites in the Savannah River. Sampling was conducted in 1996 to 1998, 2000, and 2003. Four bioassessment methods were used to evaluate ecological conditions in the IOU streams: the Index of Biotic Integrity, the Fish Health Assessment Index, measurement of fish tissue contaminant levels, and two benthic macroinvertebrate indices. The Index of Biotic Integrity (IBI) is an EPA supported method based on comparison of ecologically important and sensitive fish assemblage variables between potentially disturbed and reference (i.e., undisturbed) sites. It is designed to assess the ability of a stream to support a self-sustaining biological community and ecological processes typical of undisturbed, natural conditions. Since many types of contaminants can bioaccumulate, fish tissue contaminant data were used to determine the types of chemicals fish were exposed to and their relative magnitudes among IOUs. The Fish Health Assessment Index (HAI) is an EPA supported method for assessing

  5. Design concepts for an integrated control room used as a site-wide operations facility

    International Nuclear Information System (INIS)

    Simon, B.H.; Raghavan, R.; Ujita, H.; Utena, S.; Sakuma, A.; Itoh, T.; Fukura, M.; Ono, I.

    1995-01-01

    The concept of an Integrated Main Control Room (IMCR) evolved from surveys conducted by Tokyo Electric Power Company (TEPCO) with plant managers and workers as their existing GE-type boiling water reactors (BWRs) on the need for improved operating conditions in a new generation of reactors being developed for the next century (around 2010). These reactors will be a further enhancement of the advanced boiling water reactors (ABWRs) now being constructed at the Kashiwazaki-Kariwa site in Japan (no.6 and no.7). TEPCO also saw a need for new thinking on control room design because of projected social conditions in Japan for the 21st century. These projections forecast a smaller number of skilled engineering graduates and those graduates less willing to work in nuclear power because such work is seen as unappealing, conducted in remote geographical locations, and requiring extensive night duty. As one solution to reducing operator burden and decreasing the night shift staff, while making nuclear plant operation more interesting for the operators and reducing labor and construction costs, the IMCR was conceived. (author)

  6. Site operations

    International Nuclear Information System (INIS)

    House, W.B.; Ebenhack, D.G.

    1989-01-01

    This chapter is a discussion of the management and operations practices used at the Barnwell Waste Management Facility in Barnwell, SC. The following topics are discussed: (1) Waste receiving and inspection, including manifest and certificates of compliance, radiological surveys, disposition of nonconforming items, and decontamination and disposition of secondary waste streams; (2) Waste disposal, including Title 10 CFR 61 requirements, disposal area evaluations, shipment offloading, container emplacement, and radiation protection; (3) Trench closure, including trench backfilling, trench capping, and permanent markers; (4) Site maintenance and stabilization, including trench maintenance, surface water management, and site closure activities; (5) Site monitoring programs, including operational monitoring, and environmental monitoring program; (6) Personnel training and qualifications, including basic training program, safety training program, special skills training, and physical qualifications; (7) Records management, including waste records, personnel training records, personnel dosimetry records, site monitoring records, trench qualification and construction records, and site drawings and stabilization records; (8) Site security; (9) Emergency response plans; and (10) Quality assurance

  7. Retroviral integration: Site matters

    Science.gov (United States)

    Demeulemeester, Jonas; De Rijck, Jan

    2015-01-01

    Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integration machinery is guided to particular chromatin contexts. As the viral integrase captures a local target nucleosome, specific contacts introduce fine‐grained biases in the integration site distribution. In vivo, the established population of proviruses is subject to both positive and negative selection, thereby continuously reshaping the integration site distribution. By affecting stochastic proviral expression as well as the mutagenic potential of the virus, integration site choice may be an inherent part of the evolutionary strategies used by different retroviruses to maximise reproductive success. PMID:26293289

  8. Integrated solution for field operations

    Energy Technology Data Exchange (ETDEWEB)

    Aubin, Renaud; Dionis, Francois [EDF, Chatou (France)

    2014-08-15

    This document presents our approach to design and to implement mobile applications for field operations. Internal on-field studies yield to the fact that the value added by mobile solutions is correlated with the easiness of their integration with each other and with the underlying information systems. Moreover, the fast-growing mobile market brings new concepts to the mass and industrial applications design can benefit from these. As a consequence, a simple components-based approach has been applied to design and develop mobile applications for field operations and on-site experiments of the resulting applications have been conducted.

  9. Integrated solution for field operations

    International Nuclear Information System (INIS)

    Aubin, Renaud; Dionis, Francois

    2014-01-01

    This document presents our approach to design and to implement mobile applications for field operations. Internal on-field studies yield to the fact that the value added by mobile solutions is correlated with the easiness of their integration with each other and with the underlying information systems. Moreover, the fast-growing mobile market brings new concepts to the mass and industrial applications design can benefit from these. As a consequence, a simple components-based approach has been applied to design and develop mobile applications for field operations and on-site experiments of the resulting applications have been conducted

  10. Integrated solution for field operations

    International Nuclear Information System (INIS)

    Aubin, Renaud; Dionis, Francois

    2014-01-01

    This paper presents the authors' approach to design and to implement mobile applications for field operations. Internal on-field studies can yield the fact that the value-added by mobile solutions is correlated with the easiness of their integration with each other and with the underlying information systems. Moreover, the fast-growing mobile market brings new concepts to the mass and industrial applications design can benefit from these. As a consequence, a simple components-based approach has been applied to design and develop mobile applications for field operations and on-site experiments of the resulting applications have been conducted. (author)

  11. Automating ATLAS Computing Operations using the Site Status Board

    CERN Document Server

    Andreeva, J; The ATLAS collaboration; Campana, S; Di Girolamo, A; Espinal Curull, X; Gayazov, S; Magradze, E; Nowotka, MM; Rinaldi, L; Saiz, P; Schovancova, J; Stewart, GA; Wright, M

    2012-01-01

    The automation of operations is essential to reduce manpower costs and improve the reliability of the system. The Site Status Board (SSB) is a framework which allows Virtual Organizations to monitor their computing activities at distributed sites and to evaluate site performance. The ATLAS experiment intensively uses SSB for the distributed computing shifts, for estimating data processing and data transfer efficiencies at a particular site, and for implementing automatic exclusion of sites from computing activities, in case of potential problems. ATLAS SSB provides a real-time aggregated monitoring view and keeps the history of the monitoring metrics. Based on this history, usability of a site from the perspective of ATLAS is calculated. The presentation will describe how SSB is integrated in the ATLAS operations and computing infrastructure and will cover implementation details of the ATLAS SSB sensors and alarm system, based on the information in SSB. It will demonstrate the positive impact of the use of SS...

  12. Integrated Closure and Monitoring Plan for the Area 3 and Area 5 Radioactive Waste Management Sites at the Nevada Test Site

    International Nuclear Information System (INIS)

    Bechtel Nevada

    2005-01-01

    This document is an integrated plan for closing and monitoring two low-level radioactive waste disposal sites at the Nevada Test Site. This document is an integrated plan for closing and monitoring two low-level radioactive waste disposal sites at the Nevada Test Site (NTS). The Area 3 and Area 5 Radioactive Waste Management Sites (RWMSs) are managed and operated by Bechtel Nevada (BN) for the U.S. Department of Energy's (DOE's) National Nuclear Security Administration Nevada Site Office (NNSA/NSO). The Integrated Closure and Monitoring Plan (ICMP) for these sites is based on guidance for developing closure plans issued by the DOE (DOE, 1999a). The plan does not closely follow the format suggested by the DOE guidance to better accommodate differences between the two RWMSs, especially in terms of operations and site characteristics. The modification reduces redundancy and provides a smoother progression of the discussion. Further, much of the information that would be included in the individual plans is the same, and integration provides efficient presentation. A cross-walk between the contents of the ICMP and the DOE guidance is given in Appendix A. Closure and monitoring were integrated because monitoring measures the degree to which the operational and closed disposal facilities are meeting performance objectives specified in the manual to DOE Order O 435.1. Department of Energy Order 435.1 governs management of radioactive waste, and associated with it are Manual DOE M 435.1-1 and Guidance DOE G 435.1-1. The performance objectives are intended to ensure protection of workers, the public, and the environment from radiological exposure associated with the RWMSs now and in the future

  13. Comprehensive, integrated, remote sensing at DOE sites

    International Nuclear Information System (INIS)

    Lackey, J.G.; Burson, Z.G.

    1985-01-01

    The Department of Energy has established a program called Comprehensive, Integrated Remote Sensing (CIRS). The overall objective of the program is to provide a state-of-the-art data base of remotely sensed data for all users of such information at large DOE sites. The primary types of remote sensing provided, at present, consist of the following: large format aerial photography, video from aerial platforms, multispectral scanning, and airborne nuclear radiometric surveys. Implementation of the CIRS Program by EG and G Energy Measurements, Inc. began with field operations at the Savannah River Plant in 1982 and is continuing at that DOE site at a level of effort of about $1.5 m per year. Integrated remote sensing studies were subsequently extended to the West Valley Demonstration Project in this summer and fall of 1984. It is expected that the Program will eventually be extended to cover all large DOE sites on a continuing basis

  14. Integrating Risk Analyses and Tools at the DOE Hanford Site

    International Nuclear Information System (INIS)

    LOBER, R.W.

    2002-01-01

    Risk assessment and environmental impact analysis at the U.S. Department of Energy (DOE) Hanford Site in Washington State has made significant progress in refining the strategy for using risk analysis to support closing of several hundred waste sites plus 149 single-shell tanks at the Hanford Site. A Single-Shell Tank System Closure Work Plan outlines the current basis for closing the single-shell tank systems. An analogous site approach has been developed to address closure of aggregated groups of similar waste sites. Because of the complexity, decision time frames, proximity of non-tank farm waste sites to tank farms, scale, and regulatory considerations, various projects are providing integrated assessments to support risk analyses and decision-making. Projects and the tools that are being developed and applied at Hanford to support retrieval and cleanup decisions include: (1) Life Cycle Model (LCM) and Risk Receptor Model (RRM)--A site-level set of tools to support strategic analyses through scoping level risk management to assess different alternatives and options for tank closure. (2) Systems Assessment Capability for Integrated Groundwater Nadose Zone (SAC) and the Site-Wide Groundwater Model (SWGM)--A site-wide groundwater modeling system coupled with a risk-based uncertainty analysis of inventory, vadose zone, groundwater, and river interactions for evaluating cumulative impacts from individual and aggregate waste sites. (3) Retrieval Performance Evaluation (RPE)--A site-specific, risk-based methodology developed to evaluate performance of waste retrieval, leak detection and closure on a tank-specific basis as a function of past tank Leaks, potential leakage during retrieval operations, and remaining residual waste inventories following completion of retrieval operations. (4) Field Investigation Report (FIR)--A corrective action program to investigate the nature and extent of past tank leaks through characterization activities and assess future impacts to

  15. The Site Approach - Lessons Learned from the Integrated Safeguards Approach for JNC-1

    International Nuclear Information System (INIS)

    Kikuchi, M.; Iso, S.; Tomine, K.; Hirato, Y.; Namekawa, M.; Takasugi, N.; Watanabe, M.; Tsutaki, Y.; Asano, T.; Nagatani, T.; Ninagawa, J.; Fujiwara, S.; Takahashi, S.; Kimura, T.; Kodani, Y.; Fukuhara, J.; Miyaji, N.; Kawakami, Y.; Koizumi, A.; Yamazaki, Y.; Nishinosono, S.; Sasaki, K.

    2010-01-01

    Integrated safeguards approaches for specific sites are recognized important elements in the design of a State-level approach under the concept of grouping facilities. Japan and the IAEA agreed further improvement of integrated safeguards implementation in effective and efficient manner, particularly at large complex nuclear sites in Japan. Japan and the IAEA developed the integrated safeguards approach for specific sites defined at Article 18 of Additional Protocol. In 2008, the IAEA started the three-year test implementation of JNC-1 site approach for improving the effectiveness and efficiency of the safeguards implementation of UDU material handling facilities. Japan and IAEA agreed to adopt the sector concept in order to make clear of subjected nuclear material to be verified. The sector is defined as spatial assignment that treats the same material stratum beyond MBAs in the site. The arrangement of MBAs and related material balance calculations as well as statistical analysis is maintained as a fundamental safeguards measure. At the boundaries of each sector, appropriate unattended NDA system and/or C/S system are installed, and material flows across the boundaries are verified by the system or attendance of resident inspectors. For inventory verification of the nuclear material stayed in sectors, an appropriate numbers of randomly scheduled inspections will be implemented. IAEA can access to the randomly selected sectors within 2 hours after notification. NRTA based on frequent operator's declaration will be performed for achievement of timeliness detection goal. The JNC-1 site approach has been implemented under the enhanced co-operation between the IAEA and SSAC through joint use of equipment and arrangements for DA analysis. Especially, national inspectors are working with IAEA together for coordination with operators. Because NMCC lab analyses all DA samples taken from facilities and the analysis results will be shared by the IAEA, certain numbers of DA

  16. Remotely operated excavator needs assessment/site visit summary

    Energy Technology Data Exchange (ETDEWEB)

    Straub, J.; Haller, S.; Worsley, R. [Westinghouse Environmental Management Co. of Ohio, Cincinnati, OH (United States); King, M. [THETA Technology Inc. (United States)

    1992-12-02

    The Uranium in Soils Integrated Demonstration requested an assessment of soil excavation needs relative to soil remediation. The following list identifies the DOE sites assessed: Mound Laboratory, Paducah Gaseous Diffusion Plant, Portsmouth Gaseous Diffusion Plant, Nevada Test Site, Lawrence Livermore National Laboratory, Rocky Flats Plant, Los Alamos National Laboratory, Sandia National Laboratory, Idaho National Engineering Laboratory, Hanford Site, and Fernald Site. The reviewed sites fall into one or more of the following three categories: production, EPA National Priorities List, or CERCLA (superfund) designation. Only three of the sites appear to have the need for a remotely operated excavator rope. Hanford and Idaho Falls have areas of high-level radioactive contamination either buried or in/under buildings. The Fernald site has a need for remote operated equipment of different types. It is their feeling that remote equipment can be used to remove the health dangers to humans by removing them from the area. Most interviewees stated that characterization technologies needs are more immediate concern over excavation. In addition, the sites do not have similar geographic conditions which would aid in the development of a generic precision excavator. The sites visited were not ready to utilize or provide the required design information necessary to draft a performance specification. This creates a strong case against the development of one type of ROPE for use at these sites. Assuming soil characterization technology/methodology is improved sufficiently to allow accurate and real time field characterization then development of a precision excavator might be pursued based on FEMP needs, since the FEMP`s sole scope of work is remediation. The excavator could then be used/tested and then later modified for other sites as warranted.

  17. Hanford and Savannah River Site Programmatic and Technical Integration

    International Nuclear Information System (INIS)

    Ramsey, William Gene

    2013-01-01

    Abstract only. The Hanford Site and the Savannah River Site (SRS) were the primary plutonium production facilities within the U.S. nuclear weapons complex. Radioactive wastes were generated as part of these missions and are stored in similar fashion. The majority of radioactivity maintained by the two sites is located in underground carbon steel tanks in the physical form of supernatant, saltcake, or sludge. Disposition of SRS tank waste is ongoing by converting it into glass (pathway for sludge and radionuclides separated from supernatant or dissolved saltcake) or cement (pathway for the decontaminated supernatant and dissolved saltcake). Tank closure activity has also begun at SRS and will continue for the duration of mission. The Hanford tank waste inventory is roughly 2/3rds larger than SRS's by volume- but nominally half the radioactivity. The baseline disposition path includes high-level and low-activity waste vitrification with separate disposition of contact-handled transuranic tank waste. Retrieval of tank waste from aging single shell tanks (SSTs) into double-shell tanks (DSTs) is currently ongoing. As vitrification commences later this decade, Hanford will be in a similar operations mode as SRS. Site integration is increasing as the missions align. The ongoing integration is centered on key issues that impact both sites- regardless of mission timeframe. Three recent workshop exchanges have been held to improve communication with the primary intent of improving operations and technical work organization. The topics of these workshops are as follows: DST space utilization, optimization, and closure; Waste Feed Qualification; and, Cementitious Waste Forms. Key goals for these and future exchanges include aligning research and technology, preparing for joint initiatives (to maximize budgetary value for the customer), and reviewing lessons learned. Each site has played a leading role in the development of technology and operational practices that can be used

  18. Space shuttle operations integration plan

    Science.gov (United States)

    1975-01-01

    The Operations Integration Plan is presented, which is to provide functional definition of the activities necessary to develop and integrate shuttle operating plans and facilities to support flight, flight control, and operations. It identifies the major tasks, the organizations responsible, their interrelationships, the sequence of activities and interfaces, and the resultant products related to operations integration.

  19. Automating an integrated spatial data-mining model for landfill site selection

    Science.gov (United States)

    Abujayyab, Sohaib K. M.; Ahamad, Mohd Sanusi S.; Yahya, Ahmad Shukri; Ahmad, Siti Zubaidah; Aziz, Hamidi Abdul

    2017-10-01

    An integrated programming environment represents a robust approach to building a valid model for landfill site selection. One of the main challenges in the integrated model is the complicated processing and modelling due to the programming stages and several limitations. An automation process helps avoid the limitations and improve the interoperability between integrated programming environments. This work targets the automation of a spatial data-mining model for landfill site selection by integrating between spatial programming environment (Python-ArcGIS) and non-spatial environment (MATLAB). The model was constructed using neural networks and is divided into nine stages distributed between Matlab and Python-ArcGIS. A case study was taken from the north part of Peninsular Malaysia. 22 criteria were selected to utilise as input data and to build the training and testing datasets. The outcomes show a high-performance accuracy percentage of 98.2% in the testing dataset using 10-fold cross validation. The automated spatial data mining model provides a solid platform for decision makers to performing landfill site selection and planning operations on a regional scale.

  20. Integrating risks at contaminated sites

    International Nuclear Information System (INIS)

    MacDonell, M.; Habegger, L.; Nieves, L.; Schreiber, Z.; Travis, C.

    2000-01-01

    The U.S. Department of Energy (DOE) is responsible for a number of large sites across the country that were radioactively and chemically contaminated by past nuclear research, development, and production activities. Multiple risk assessments are being conducted for these sites to evaluate current conditions and determine what measures are needed to protect human health and the environment from today through the long term. Integrating the risks associated with multiple contaminants in different environmental media across extensive areas, over time periods that extend beyond 1,000 years, and for a number of different impact categories--from human health and ecological to social and economic--represents a considerable challenge. A central element of these integrated analyses is the ability to reflect key interrelationships among environmental resources and human communities that may be adversely affected by the actions or inactions being considered for a given site. Complicating the already difficult task of integrating many kinds of risk is the importance of reflecting the diverse values and preferences brought to bear by the multiple parties interested in the risk analysis process and outcome. An initial conceptual framework has been developed to provide an organized structure to this risk integration, with the aim of supporting effective environmental management decisions. This paper highlights key issues associated with comprehensive risk integration and offers suggestions developed from preliminary work at a complex DOE site

  1. Opportunities for Launch Site Integrated System Health Engineering and Management

    Science.gov (United States)

    Waterman, Robert D.; Langwost, Patricia E.; Waterman, Susan J.

    2005-01-01

    The launch site processing flow involves operations such as functional verification, preflight servicing and launch. These operations often include hazards that must be controlled to protect human life and critical space hardware assets. Existing command and control capabilities are limited to simple limit checking durig automated monitoring. Contingency actions are highly dependent on human recognition, decision making, and execution. Many opportunities for Integrated System Health Engineering and Management (ISHEM) exist throughout the processing flow. This paper will present the current human-centered approach to health management as performed today for the shuttle and space station programs. In addition, it will address some of the more critical ISHEM needs, and provide recommendations for future implementation of ISHEM at the launch site.

  2. Meteorology in site operations

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    During the site selection and design phases of a plant, meteorological assistance must be based on past records, usually accumulated at stations not actually on the site. These preliminary atadvices will be averages and extremes that might be expected. After a location has been chosen and work has begun, current and forecast weather conditions become of immediate concern. On-site meteorological observations and forecasts have many applications to the operating program of an atomic energy site. Requirements may range from observations of the daily minimum temperatures to forecasts of radiation dosages from airborne clouds

  3. Heat integration and analysis of decarbonised IGCC sites

    Energy Technology Data Exchange (ETDEWEB)

    Ng, K.S.; Lopez, Y.; Campbell, G.M.; Sadhukhan, J. [University of Manchester, Manchester (United Kingdom). School of Chemical Engineering & Analytical Science

    2010-02-15

    Integrated gasification combined cycle (IGCC) power generation systems have become of interest due to their high combined heat and power (CHP) generation efficiency and flexibility to include carbon capture and storage (CCS) in order to reduce CO{sub 2} emissions. However, IGCC's biggest challenge is its high cost of energy production. In this study, decarbonised coal IGCC sites integrated with CCS have been investigated for heat integration and economic value analyses. It is envisaged that the high energy production cost of an IGCC site can be offset by maximising site-wide heat recovery and thereby improving the cost of electricity (COE) of CHP generation. Strategies for designing high efficiency CHP networks have been proposed based on thermodynamic heuristics and pinch theory. Additionally, a comprehensive methodology to determine the COE from a process site has been developed. In this work, we have established thermodynamic and economic comparisons between IGCC sites with and without CCS and a trade-off between the degree of decarbonisation and the COE from the heat integrated IGCC sites. The results show that the COE from the heat integrated decarbonised IGCC sites is significantly lower compared to IGCC sites without heat integration making application of CCS in IGCC sites economically competitive.

  4. Integrated Closure and Monitoring Plan for the Area 3 and Area 5 Radioactive Waste Management Sites at the Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    S. E. Rawlinson

    2001-09-01

    Bechtel Nevada (BN) manages two low-level Radioactive Waste Management Sites (RWMSs) (one site is in Area 3 and the other is in Area 5) at the Nevada Test Site (NTS) for the U.S. Department of Energy's (DOE's) National Nuclear Security Administration Nevada Operations Office (NNSA/NV). The current DOE Order governing management of radioactive waste is 435.1. Associated with DOE Order 435.1 is a Manual (DOE M 435.1-1) and Guidance (DOE G 435.1-1). The Manual and Guidance specify that preliminary closure and monitoring plans for a low-level waste (LLW) management facility be developed and initially submitted with the Performance Assessment (PA) and Composite Analysis (CA) for that facility. The Manual and Guidance, and the Disposal Authorization Statement (DAS) issued for the Area 3 RWMS further specify that the preliminary closure and monitoring plans be updated within one year following issuance of a DAS. This Integrated Closure and Monitoring Plan (ICMP) fulfills both requirements. Additional updates will be conducted every third year hereafter. This document is an integrated plan for closing and monitoring both RWMSs, and is based on guidance issued in 1999 by the DOE for developing closure plans. The plan does not follow the format suggested by the DOE guidance in order to better accommodate differences between the two RWMSs, especially in terms of operations and site characteristics. The modification reduces redundancy and provides a smoother progression of the discussion. The closure and monitoring plans were integrated because much of the information that would be included in individual plans is the same, and integration provides efficient presentation and program management. The ICMP identifies the regulatory requirements, describes the disposal sites and the physical environment where they are located, and defines the approach and schedule for both closing and monitoring the sites.

  5. Operations Management on The Construction Site

    DEFF Research Database (Denmark)

    Koch, Christian

    2004-01-01

    this as a refreshing renewal and improvement of practical operations management at the site. However this paper will present a first step of development of a new approach to operations management at the building site, which at the same time builds on, and criticize lean construction for missing the point...... of the knowledge economy. This endeavour is carried out in two ways. First by a reading of the operations management literature. Juxtaposing this with lean construction extentions and the critique developed by other scholars. And also drawing on human resource management approaches. Second through a series......” scheme. In both directions it is revealed that the human resource and knowledge element of building processes is largely left untouched by lean construction methods. It is suggested to introduce at least two more dimensions of operations management at the site than the ones offered in lean construction...

  6. Hanford Site air operating permit application

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    The Clean Air Act Amendments of 1990, which amended the Federal Clean Air Act of 1977, required that the US Environmental Protection Agency develop a national Air Operating Permit Program, which in turn would require each state to develop an Air Operating Permit Program to identify all sources of ``regulated`` pollutants. Regulated pollutants include ``criteria`` pollutants (oxides of nitrogen, sulfur oxides, total suspended particulates, carbon monoxide, particulate matter greater than 10 micron, lead) plus 189 other ``Hazardous`` Air Pollutants. The Hanford Site, owned by the US Government and operated by the US Department of Energy, Richland Operations Office, is located in southcentral Washington State and covers 560 square miles of semi-arid shrub and grasslands located just north of the confluence of the Snake and Yakima Rivers with the Columbia River. This land, with restricted public access, provides a buffer for the smaller areas historically used for the production of nuclear materials, waste storage, and waste disposal. About 6 percent of the land area has been disturbed and is actively used. The Hanford Site Air Operating Permit Application consists of more than 1,100 sources and in excess of 300 emission points. Before January 1995, the maintenance and operations contractor and the environmental restoration contractor for the US Department of Energy completed an air emission inventory on the Hanford Site. The inventory has been entered into a database so that the sources and emission points can be tracked and updated information readily can be retrieved. The Hanford Site Air Operating Permit Application contains information current as of April 19, 1995.

  7. Hanford Site air operating permit application

    International Nuclear Information System (INIS)

    1995-05-01

    The Clean Air Act Amendments of 1990, which amended the Federal Clean Air Act of 1977, required that the US Environmental Protection Agency develop a national Air Operating Permit Program, which in turn would require each state to develop an Air Operating Permit Program to identify all sources of ''regulated'' pollutants. Regulated pollutants include ''criteria'' pollutants (oxides of nitrogen, sulfur oxides, total suspended particulates, carbon monoxide, particulate matter greater than 10 micron, lead) plus 189 other ''Hazardous'' Air Pollutants. The Hanford Site, owned by the US Government and operated by the US Department of Energy, Richland Operations Office, is located in southcentral Washington State and covers 560 square miles of semi-arid shrub and grasslands located just north of the confluence of the Snake and Yakima Rivers with the Columbia River. This land, with restricted public access, provides a buffer for the smaller areas historically used for the production of nuclear materials, waste storage, and waste disposal. About 6 percent of the land area has been disturbed and is actively used. The Hanford Site Air Operating Permit Application consists of more than 1,100 sources and in excess of 300 emission points. Before January 1995, the maintenance and operations contractor and the environmental restoration contractor for the US Department of Energy completed an air emission inventory on the Hanford Site. The inventory has been entered into a database so that the sources and emission points can be tracked and updated information readily can be retrieved. The Hanford Site Air Operating Permit Application contains information current as of April 19, 1995

  8. AIS ASM Operational Integration Plan

    Science.gov (United States)

    2013-08-01

    Rack mount computer AIS Radio Interface Ethernet Switch 192.168.0.x Firewall Cable Modem 192.168.0.1 VTS Accred. Boundary AIS ASM Operational... AIS ASM Operational Integration Plan Distribution Statement A: Approved for public release; distribution is unlimited. August 2013 Report No...CD-D-07-15 AIS ASM Operational Integration Plan ii UNCLAS//Public | CG-926 R&DC | I. Gonin, et al. | Public August 2013 N O T I C

  9. Integrated initial training program for a CEGB operations engineer

    International Nuclear Information System (INIS)

    Tompsett, P.A.

    1987-01-01

    This paper considers the overall training programs undertaken by a newly appointed Operations Engineer at one of the Central Electricity Generating Board's (CEGB) Advanced Gas Cooled Reactor (AGR) nuclear power stations. The training program is designed to equip him with the skills and knowledge necessary for him to discharge his duties safely and effectively. In order to assist the learning process and achieve and integrated program, aspects of reactor technology and operation, initially the subject of theoretical presentations at the CEGB's Nuclear Power Training Center (NPTC) are reinforced by either simulation and/or practical experience on site. In the later stages plant-specific simulators, operated by trained tutors, are incorporated into the training program to provide the trainee with practical experience of plant operation. The trainee's performance is assessed throughout the program to provide feedback to the trainee, the trainers and station management

  10. Verification of geomechanical integrity and prediction of long-term mineral trapping for the Ketzin CO2 storage pilot site

    Science.gov (United States)

    Kempka, Thomas; De Lucia, Marco; Kühn, Michael

    2014-05-01

    Static and dynamic numerical modelling generally accompany the entire CO2 storage site life cycle. Thereto, it is required to match the employed models with field observations on a regular basis in order to predict future site behaviour. We investigated the coupled processes at the Ketzin CO2 storage pilot site [1] using a model coupling concept focusing on the temporal relevance of processes involved (hydraulic, chemical and mechanical) at given time-scales (site operation, abandonment and long-term stabilization). For that purpose, long-term dynamic multi-phase flow simulations [2], [3] established the basis for all simulations discussed in the following. Hereby, pressure changes resulting in geomechanical effects are largest during site operation, whereas geochemical reactions are governed by slow kinetics resulting in a long-term stabilization. To account for mechanical integrity, which may be mainly affected during site operation, we incorporated a regional-scale coupled hydro-mechanical model. Our simulation results show maximum ground surface displacements of about 4 mm, whereas shear and tensile failure are not observed. Consequently, the CO2 storage operation at the Ketzin pilot site does not compromise reservoir, caprock and fault integrity. Chemical processes responsible for mineral trapping are expected to mainly occur during long-term stabilization at the Ketzin pilot site [4]. Hence, our previous assessment [3] was extended by integrating two long-term mineral trapping scenarios. Thereby, mineral trapping contributes to the trapping mechanisms with 11.7 % after 16,000 years of simulation in our conservative and with 30.9 % in our maximum reactivity scenarios. Dynamic flow simulations indicate that only 0.2 % of the CO2 injected (about 67,270 t CO2 in total) is in gaseous state, but structurally trapped after 16,000 years. Depending on the studied long-term scenario, CO2 dissolution is the dominating trapping mechanism with 68.9 % and 88

  11. Hazardous waste operational plan for site 300

    International Nuclear Information System (INIS)

    Roberts, R.S.

    1982-01-01

    This plan outlines the procedures and operations used at LLNL's Site 300 for the management of the hazardous waste generated. This waste consists primarily of depleted uranium (a by-product of U-235 enrichment), beryllium, small quantities of analytical chemicals, industrial type waste such as solvents, cleaning acids, photographic chemicals, etc., and explosives. This plan details the operations generating this waste, the proper handling of this material and the procedures used to treat or dispose of the hazardous waste. A considerable amount of information found in this plan was extracted from the Site 300 Safety and Operational Manual written by Site 300 Facility personnel and the Hazards Control Department

  12. Integration of Environmental Compliance at the Savannah River Site - 13024

    International Nuclear Information System (INIS)

    Hoel, David; Griffith, Michael

    2013-01-01

    The Savannah River Site (SRS) is a large federal installation hosting diverse missions and multiple organizations with competing regulatory needs. Accordingly, there was a need to integrate environmental compliance strategies to ensure the consistent flow of information between Department of Energy-Savannah River (DOE-SR), the regulatory agencies and other interested parties. In order to meet this objective, DOE and major SRS contractors and tenants have committed to a strategy of collaboratively working together to ensure that a consistent, integrated, and fully coordinated approach to environmental compliance and regulator relationships is maintained. DOE-SR and Savannah River Nuclear Solutions, LLC, the SRS management and operations contractor, have established an environmental compliance integration process that provides for the consistent flow down of requirements to projects, facilities, SRS contractors, and subcontractors as well as the upward flow of information to assist in the early identification and resolution of environmental regulatory issues and enhancement of compliance opportunities. In addition, this process strongly fosters teamwork to collaboratively resolve complex regulatory challenges, promote pollution prevention and waste minimization opportunities to advance site missions in a manner that balances near-term actions with the long-term site vision, while being protective of human health and the environment. Communication tools are being utilized, some with enhancements, to ensure appropriate information is communicated to all levels with environmental responsibility at SRS. SRS internal regulatory integration is accomplished through a variety of informational exchange forums (e.g., Challenges, Opportunities and Resolution (COR) Team, DOE's Joint Site Regulatory Integration Team, and the Senior Environmental Managers Council (SEMC)). SRS communications and problem-solving with the regulatory agencies have been enhanced through formation of an

  13. Integration of Environmental Compliance at the Savannah River Site - 13024

    Energy Technology Data Exchange (ETDEWEB)

    Hoel, David [United States Department of Energy - Savannah River Operations Office (United States); Griffith, Michael [Savannah River Nuclear Solutions, LLC (United States)

    2013-07-01

    The Savannah River Site (SRS) is a large federal installation hosting diverse missions and multiple organizations with competing regulatory needs. Accordingly, there was a need to integrate environmental compliance strategies to ensure the consistent flow of information between Department of Energy-Savannah River (DOE-SR), the regulatory agencies and other interested parties. In order to meet this objective, DOE and major SRS contractors and tenants have committed to a strategy of collaboratively working together to ensure that a consistent, integrated, and fully coordinated approach to environmental compliance and regulator relationships is maintained. DOE-SR and Savannah River Nuclear Solutions, LLC, the SRS management and operations contractor, have established an environmental compliance integration process that provides for the consistent flow down of requirements to projects, facilities, SRS contractors, and subcontractors as well as the upward flow of information to assist in the early identification and resolution of environmental regulatory issues and enhancement of compliance opportunities. In addition, this process strongly fosters teamwork to collaboratively resolve complex regulatory challenges, promote pollution prevention and waste minimization opportunities to advance site missions in a manner that balances near-term actions with the long-term site vision, while being protective of human health and the environment. Communication tools are being utilized, some with enhancements, to ensure appropriate information is communicated to all levels with environmental responsibility at SRS. SRS internal regulatory integration is accomplished through a variety of informational exchange forums (e.g., Challenges, Opportunities and Resolution (COR) Team, DOE's Joint Site Regulatory Integration Team, and the Senior Environmental Managers Council (SEMC)). SRS communications and problem-solving with the regulatory agencies have been enhanced through formation

  14. Providing an integrated waste management strategy and operation focused on project end states at the Hanford site

    International Nuclear Information System (INIS)

    Blackford, L.

    2009-01-01

    responsibilities; 3) provides a basis for budgeting; and 4) reflects a concerted goal of achieving full regulatory compliance and remediation (with enforceable milestones) in an aggressive manner. CHPRC's approach to safely accelerate and accomplish solid waste stabilization and disposition provides an integrated waste management (WM) strategy and operation focused on project end states. CHPRC will present planned approaches for waste stabilization and disposition based on lessons learned at other DOE sites and discuss optimizing solutions to accelerating TPA milestone M-91 TRU waste retrieval activities through innovation and increased production, Point of Generation waste management, unique transport and packaging systems that are re-usable, and in-field waste handling and treatment processes that have generated cost saving and are generating early-completion cost savings of $66 million on the PRC that can be redirected to other pressing Hanford Plateau Remediation Contract (PRC) projects. (authors)

  15. On the Riesz representation theorem and integral operators ...

    African Journals Online (AJOL)

    We present a Riesz representation theorem in the setting of extended integration theory as introduced in [6]. The result is used to obtain boundedness theorems for integral operators in the more general setting of spaces of vector valued extended integrable functions. Keywords: Vector integral, integral operators, operator ...

  16. Integrating UF6 Cylinder RF Tracking With Continuous Load Cell Monitoring for Verifying Declared UF6 Feed and Withdrawal Operations Verifying Declared UF6 Feed and Withdrawal Operations

    International Nuclear Information System (INIS)

    Krichinsky, Alan M.; Miller, Paul; Pickett, Chris A.; Richardson, Dave; Rowe, Nathan C.; Whitaker, J. Michael; Younkin, James R.

    2009-01-01

    Oak Ridge National Laboratory is demonstrating the integration of UF6 cylinder tracking, using RF technology, with continuous load cell monitoring (CLCM) at mock UF6 feed and withdrawal (F and W) stations. CLCM and cylinder tracking are two of several continuous-monitoring technologies that show promise in providing integrated safeguards of F and W operations at enrichment plants. Integrating different monitoring technologies allows advanced, automated event processing to screen innocuous events thereby minimizing false alerts to independent inspectors. Traditionally, international inspectors rely on batch verification of material inputs and outputs derived from operator declarations and periodic on-site inspections at uranium enrichment plants or other nuclear processing facilities. Continuously monitoring F and W activities between inspections while providing filtered alerts of significant operational events will substantially increase the amount of valuable information available to inspectors thereby promising to enhance the effectiveness of safeguards and to improve efficiency in conducting on-site inspections especially at large plants for ensuring that all operations are declared.

  17. Remedial investigation/feasibility study work plan for the 100-BC-5 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-07-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The Tri-Party Agreement requires that the cleanup programs at the Hanford Site integrate the requirements of CERCLA, RCRA, and Washington State's dangerous waste (the state's RCRA-equivalent) program. This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-BC-5 operable unit. The 100-B/C Area consists of the 100-BC-5 groundwater operable unit and four source operable units. The 100-BC-5 operable unit includes all contamination found in the aquifer soils and water beneath the 100-B/C Area. Source operable units include facilities and unplanned release sites that are potential sources of contamination

  18. Operational experience with CMS Tier-2 sites

    International Nuclear Information System (INIS)

    Gonzalez Caballero, I

    2010-01-01

    In the CMS computing model, more than one third of the computing resources are located at Tier-2 sites, which are distributed across the countries in the collaboration. These sites are the primary platform for user analyses; they host datasets that are created at Tier-1 sites, and users from all CMS institutes submit analysis jobs that run on those data through grid interfaces. They are also the primary resource for the production of large simulation samples for general use in the experiment. As a result, Tier-2 sites have an interesting mix of organized experiment-controlled activities and chaotic user-controlled activities. CMS currently operates about 40 Tier-2 sites in 22 countries, making the sites a far-flung computational and social network. We describe our operational experience with the sites, touching on our achievements, the lessons learned, and the challenges for the future.

  19. Integrated approach to planning the remediation of sites undergoing decommissioning

    International Nuclear Information System (INIS)

    2009-01-01

    between decommissioning and site remediation in order to allow for the implementation of both processes in an integrated and cost effective way. The publication reviews the planning procedures for, and operational constraints on, partial remediation of sites and examines, with the aid of case studies, the advantages of integrating it with decommissioning. With a discussion of issues relevant to tackling the conceptual, management and technical problems of such a transition, this report constitutes an important resource for engineers and regulatory authorities involved in the remediation of contaminated sites

  20. A Generalized Analytic Operator-Valued Function Space Integral and a Related Integral Equation

    International Nuclear Information System (INIS)

    Chang, K.S.; Kim, B.S.; Park, C.H.; Ryu, K.S.

    2003-01-01

    We introduce a generalized Wiener measure associated with a Gaussian Markov process and define a generalized analytic operator-valued function space integral as a bounded linear operator from L p into L p-ci r cumflexprime (1< p ≤ 2) by the analytic continuation of the generalized Wiener integral. We prove the existence of the integral for certain functionals which involve some Borel measures. Also we show that the generalized analytic operator-valued function space integral satisfies an integral equation related to the generalized Schroedinger equation. The resulting theorems extend the theory of operator-valued function space integrals substantially and previous theorems about these integrals are generalized by our results

  1. Integrated Life Cycle Management: A Strategy for Plants to Extend Operating Lifetimes Safely with High Operational Reliability

    International Nuclear Information System (INIS)

    Esselman, Thomas; Bruck, Paul; Mengers, Charles

    2012-01-01

    Nuclear plant operators are studying the possibility of extending their existing generating facilities operating lifetime to 60 years and beyond. Many nuclear plants have been granted licenses to operate their facilities beyond the original 40 year term; however, in order to optimize the long term operating strategies, plant decision-makers need a consistent approach to support their options. This paper proposes a standard methodology to support effective decision-making for the long-term management of selected station assets. Methods detailed are intended to be used by nuclear plant site management, equipment reliability personnel, long term planners, capital asset planners, license renewal staff, and others that intend to look at operation between the current time and the end of operation. This methodology, named Integrated Life Cycle Management (ILCM), will provide a technical basis to assist decision makers regarding the timing of large capital investments required to get to the end of operation safely and with high plant reliability. ILCM seeks to identify end of life cycle failure probabilities for individual plant large capital assets and attendant costs associated with their refurbishment or replacement. It will provide a standard basis for evaluation of replacement and refurbishment options for these components. ILCM will also develop methods to integrate the individual assets over the entire plant thus assisting nuclear plant decision-makers in their facility long term operating strategies. (author)

  2. Improvement of Off-site Dose Assessment Code for Operating Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Juyub; Kim, Juyoul; Shin, Kwangyoung [FNC Technology Co. Ltd., Yongin (Korea, Republic of); You, Songjae; Moon, Jongyi [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2014-05-15

    XOQDOQ code which calculates atmospheric Dispersion factor was included into INDAC also. A research on the improvement of off-site dose assessment system for an operating nuclear power plant was performed by KINS in 2011. As a result, following improvements were derived: - Separation of dose assessment for new and existing facilities - Update of food ingestion data - Consideration of multi-unit operation and so on In order to reflect the results, INDAC is under modification. INDAC is an integrated dose assessment code for an operating nuclear power plant and consists of three main modules: XOQDOQ, GASDOS and LIQDOS. The modules are under modification in order to improve the accuracy of assessment and usability. Assessment points for multi-unit release can be calculated through the improved code and the method on dose assessment for multi-unit release has been modified, so that the dose assessment result of multi-unit site becomes more realistic by relieving excessive conservatism. Finally, as the accuracy of calculation modules has been improved, the reliability of dose assessment result has been strengthened.

  3. Completely integrable operator evolution equations. II

    International Nuclear Information System (INIS)

    Chudnovsky, D.V.

    1979-01-01

    The author continues the investigation of operator classical completely integrable systems. The main attention is devoted to the stationary operator non-linear Schroedinger equation. It is shown that this equation can be used for separation of variables for a large class of completely integrable equations. (Auth.)

  4. Integrated Ground Operations Demonstration Units

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of the AES Integrated Ground Operations Demonstration Units (IGODU) project is to demonstrate cost efficient cryogenic operations on a relevant...

  5. Site-Wide Integrated Water Monitoring - Defining and Implementing Sampling Objectives to Support Site Closure - 13060

    International Nuclear Information System (INIS)

    Wilborn, Bill; Knapp, Kathryn; Farnham, Irene; Marutzky, Sam

    2013-01-01

    The Underground Test Area (UGTA) activity is responsible for assessing and evaluating the effects of the underground nuclear weapons tests on groundwater at the Nevada National Security Site (NNSS), formerly the Nevada Test Site (NTS), and implementing a corrective action closure strategy. The UGTA strategy is based on a combination of characterization, modeling studies, monitoring, and institutional controls (i.e., monitored natural attenuation). The closure strategy verifies through appropriate monitoring activities that contaminants of concern do not exceed the SDWA at the regulatory boundary and that adequate institutional controls are established and administered to ensure protection of the public. Other programs conducted at the NNSS supporting the environmental mission include the Routine Radiological Environmental Monitoring Program (RREMP), Waste Management, and the Infrastructure Program. Given the current programmatic and operational demands for various water-monitoring activities at the same locations, and the ever-increasing resource challenges, cooperative and collaborative approaches to conducting the work are necessary. For this reason, an integrated sampling plan is being developed by the UGTA activity to define sampling and analysis objectives, reduce duplication, eliminate unnecessary activities, and minimize costs. The sampling plan will ensure the right data sets are developed to support closure and efficient transition to long-term monitoring. The plan will include an integrated reporting mechanism for communicating results and integrating process improvements within the UGTA activity as well as between other U.S. Department of Energy (DOE) Programs. (authors)

  6. Hanford Site's Integrated Risk Assessment Program: No-intervention risk assessment

    International Nuclear Information System (INIS)

    Mahaffey, J.A.; Dukelow, J.S. Jr.; Stenner, R.D.

    1994-08-01

    The long-term goal of the Integrated Risk Assessment program (IRAP) is to estimate risks to workers, the public, organizations, and groups with reserved rights to Site access, the ecosystem, and natural resources to aid in managing environmental restoration and waste management at the Hanford Site. For each of these, information is needed about current risks, risks during cleanup, and endstate risks. The objective is three-fold: to determine if and when to remediate, and to what extent; to identify information unavailable but needed to make better cleanup decisions; to establish technology performance criteria for achieving desired cleanup levels; to understand costs and benefits of activities from a Site-wide perspective. The no-intervention risk, assessment is the initial evaluation of public health risks conducted under IRAP. The objective is to identify types of activities that the US Department of Energy (DOE) must accomplish for closure of the Hanford Site, defined as no further DOE intervention. There are two primary conclusions from the no-intervention risk assessment. First, some maintenance and operations activities at Hanford must be continued to protect the public from grave risks. However, when large Hanford expenditures are compared to cleanup progress, funds expended for maintenance and operations must be put in proper perspective. Second, stakeholder's emphasis on public risks at Hanford, as indicated by remediation priorities, are not in line with those estimated. The focus currently is on compliance with regulations, and on dealing with issues which are visible to stakeholders

  7. HIV integration sites and implications for maintenance of the reservoir.

    Science.gov (United States)

    Symons, Jori; Cameron, Paul U; Lewin, Sharon R

    2018-03-01

    To provide an overview of recent research of how HIV integration relates to productive and latent infection and implications for cure strategies. How and where HIV integrates provides new insights into how HIV persists on antiretroviral therapy (ART). Clonal expansion of infected cells with the same integration site demonstrates that T-cell proliferation is an important factor in HIV persistence, however, the driver of proliferation remains unclear. Clones with identical integration sites harbouring defective provirus can accumulate in HIV-infected individuals on ART and defective proviruses can express RNA and produce protein. HIV integration sites differ in clonally expanded and nonexpanded cells and in latently and productively infected cells and this influences basal and inducible transcription. There is a growing number of cellular proteins that can alter the pattern of integration to favour latency. Understanding these pathways may identify new interventions to eliminate latently infected cells. Using advances in analysing HIV integration sites, T-cell proliferation of latently infected cells is thought to play a major role in HIV persistence. Clonal expansion has been demonstrated with both defective and intact viruses. Production of viral RNA and protein from defective viruses may play a role in driving chronic immune activation. The site of integration may determine the likelihood of proliferation and the degree of basal and induced transcription. Finally, host factors and gene expression at the time of infection may determine the integration site. Together these new insights may lead to novel approaches to elimination of latently infected cells.

  8. Operational Amplifer Integrator

    NARCIS (Netherlands)

    van Tuijl, Adrianus Johannes Maria

    2003-01-01

    An integrator circuit comprises an operational amplifier which has a transistor stage (1) with an input terminal (4) and an output terminal (3), a feedback capacitor (2) connected between the input terminal (4) and the output terminal (3), and a resistor (5) connected to the input terminal (4), and

  9. Selective pressures to maintain attachment site specificity of integrative and conjugative elements.

    Directory of Open Access Journals (Sweden)

    Kayla L Menard

    Full Text Available Integrative and conjugative elements (ICEs are widespread mobile genetic elements that are usually found integrated in bacterial chromosomes. They are important agents of evolution and contribute to the acquisition of new traits, including antibiotic resistances. ICEs can excise from the chromosome and transfer to recipients by conjugation. Many ICEs are site-specific in that they integrate preferentially into a primary attachment site in the bacterial genome. Site-specific ICEs can also integrate into secondary locations, particularly if the primary site is absent. However, little is known about the consequences of integration of ICEs into alternative attachment sites or what drives the apparent maintenance and prevalence of the many ICEs that use a single attachment site. Using ICEBs1, a site-specific ICE from Bacillus subtilis that integrates into a tRNA gene, we found that integration into secondary sites was detrimental to both ICEBs1 and the host cell. Excision of ICEBs1 from secondary sites was impaired either partially or completely, limiting the spread of ICEBs1. Furthermore, induction of ICEBs1 gene expression caused a substantial drop in proliferation and cell viability within three hours. This drop was dependent on rolling circle replication of ICEBs1 that was unable to excise from the chromosome. Together, these detrimental effects provide selective pressure against the survival and dissemination of ICEs that have integrated into alternative sites and may explain the maintenance of site-specific integration for many ICEs.

  10. LLNL Experimental Test Site (Site 300) Potable Water System Operations Plan

    Energy Technology Data Exchange (ETDEWEB)

    Ocampo, R. P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bellah, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-09-14

    The existing Lawrence Livermore National Laboratory (LLNL) Site 300 drinking water system operation schematic is shown in Figures 1 and 2 below. The sources of water are from two Site 300 wells (Well #18 and Well #20) and San Francisco Public Utilities Commission (SFPUC) Hetch-Hetchy water through the Thomas shaft pumping station. Currently, Well #20 with 300 gallons per minute (gpm) pump capacity is the primary source of well water used during the months of September through July, while Well #18 with 225 gpm pump capacity is the source of well water for the month of August. The well water is chlorinated using sodium hypochlorite to provide required residual chlorine throughout Site 300. Well water chlorination is covered in the Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Chlorination Plan (“the Chlorination Plan”; LLNL-TR-642903; current version dated August 2013). The third source of water is the SFPUC Hetch-Hetchy Water System through the Thomas shaft facility with a 150 gpm pump capacity. At the Thomas shaft station the pumped water is treated through SFPUC-owned and operated ultraviolet (UV) reactor disinfection units on its way to Site 300. The Thomas Shaft Hetch- Hetchy water line is connected to the Site 300 water system through the line common to Well pumps #18 and #20 at valve box #1.

  11. Industrial implementation issues of Total Site Heat Integration

    International Nuclear Information System (INIS)

    Chew, Kew Hong; Klemeš, Jiří Jaromír; Wan Alwi, Sharifah Rafidah; Abdul Manan, Zainuddin

    2013-01-01

    Heat Integration has been a well-established energy conservation strategy in the industry. Total Site Heat Integration (TSHI) has received growing interest since its inception in the 90s. The methodology has been used with certain simplifications to solve TSHI problems. This paper investigates the main issues that can influence the practical implementation of TSHI in the industry. The main aim is to provide an assessment and possible guidance for future development and extension of the TSHI methodology from the industrial perspective. Several key issues have been identified as being of vital importance for the industries: design, operation, reliability/availability/maintenance, regulatory/policy and economics. Design issues to consider include plant layout, pressure drop, etc. For operation, issues such as startup and shutdown need to be considered. Reliability, availability and maintenance (RAM) are important as they directly affect the production. Relevant government policy and incentives are also important when considering the options for TSHI. Finally, a TSHI system needs to be economically viable. This paper highlights the key issues to be considered for a successful implementation of TSHI. The impacts of these issues on TS integration are summarised in a matrix, which forms a basis for an improved and closer-to-real-life implementation of the TSHI methodology. Highlights: ► Current TSHI methodology has been used for solving models with certain simplifications. ► Several issues that can influence practical implementation of TSHI are identified. ► Impacts of these issues on safety, environment and economics are evaluated. ► The findings form a basis for an improved and practical implementation of TSHI

  12. Integrated formal operations plan

    Energy Technology Data Exchange (ETDEWEB)

    Cort, G.; Dearholt, W.; Donahue, S.; Frank, J.; Perkins, B.; Tyler, R.; Wrye, J.

    1994-01-05

    The concept of formal operations (that is, a collection of business practices to assure effective, accountable operations) has vexed the Laboratory for many years. To date most attempts at developing such programs have been based upon rigid, compliance-based interpretations of a veritable mountain of Department of Energy (DOE) orders, directives, notices, and standards. These DOE dictates seldom take the broad view but focus on highly specialized programs isolated from the overall context of formal operations. The result is a confusing array of specific, and often contradictory, requirements that produce a patchwork of overlapping niche programs. This unnecessary duplication wastes precious resources, dramatically increases the complexity of our work processes, and communicates a sense of confusion to our customers and regulators. Coupled with the artificial divisions that have historically existed among the Laboratory`s formal operations organizations (quality assurance, configuration management, records management, training, etc.), this approach has produced layers of increasingly vague and complex formal operations plans, each of which interprets its parent and adds additional requirements of its own. Organizational gridlock ensues whenever an activity attempts to implement these bureaucratic monstrosities. The integrated formal operations plan presented is to establish a set of requirements that must be met by an integrated formal operations program, assign responsibilities for implementation and operation of the program, and specify criteria against which the performance of the program will be measured. The accountable line manager specifies the items, processes, and information (the controlled elements) to which the formal operations program specified applies. The formal operations program is implemented using a graded approach based on the level of importance of the various controlled elements and the scope of the activities in which they are involved.

  13. Integrated ADIOS-IGENPRO operator advisory support system

    International Nuclear Information System (INIS)

    Lee, Dong Young; Park, J. H.; Kim, J. T.; Kim, C. H.; Park, W. M.; Hwang, I. K.; Cheon, S. W.; Song, S. J.

    2001-05-01

    The I and C systems and control rooms of nuclear power plants have been constructed by using the automatic control concept and changed to computer-based systems in nowadays. For Increase of an automation and CRT, the role of operators is changed to monitor the condition of the nuclear power plants. Therefore, the information that is offered to operators has to integrate in order for operator to understand the hole condition of plants. In commercial nuclear plants, raw data of sensors and components are shown in a control room. So, operators can not diagnose the condition of plants correctly. For a development of an integrated operator aid system which contain an alarm processing system and a fault diagnosis system, we integrated IGENPRO of ANL(Argonne National Lab.) and ADIOS of KAERI (Korea Atomic Energy Institute). IGENPRO is a fault diagnosis system contains three module such as PROTREN, PRODIAG and PROTREN. ADIOS is an alarm processing system that informs operators of important alarms. The integrated operator advisory support system developed in the research is composed of an alarm processing module and a fault diagnosis module. The alarm processing module shows important alarms to operator by using dynamic alarm filtering methods. The fault diagnosis module shows the cause of faults of sensors and hardwares

  14. Integrated ADIOS-IGENPRO operator advisory support system

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Young; Park, J. H.; Kim, J. T.; Kim, C. H.; Park, W. M.; Hwang, I. K.; Cheon, S. W.; Song, S. J

    2001-05-01

    The I and C systems and control rooms of nuclear power plants have been constructed by using the automatic control concept and changed to computer-based systems in nowadays. For Increase of an automation and CRT, the role of operators is changed to monitor the condition of the nuclear power plants. Therefore, the information that is offered to operators has to integrate in order for operator to understand the hole condition of plants. In commercial nuclear plants, raw data of sensors and components are shown in a control room. So, operators can not diagnose the condition of plants correctly. For a development of an integrated operator aid system which contain an alarm processing system and a fault diagnosis system, we integrated IGENPRO of ANL(Argonne National Lab.) and ADIOS of KAERI (Korea Atomic Energy Institute). IGENPRO is a fault diagnosis system contains three module such as PROTREN, PRODIAG and PROTREN. ADIOS is an alarm processing system that informs operators of important alarms. The integrated operator advisory support system developed in the research is composed of an alarm processing module and a fault diagnosis module. The alarm processing module shows important alarms to operator by using dynamic alarm filtering methods. The fault diagnosis module shows the cause of faults of sensors and hardwares.

  15. An integrated operation mode for green logistics of enterprises

    Institute of Scientific and Technical Information of China (English)

    Yu Chengxue; Wu Chunyou; Fan Yu

    2006-01-01

    The integrated operation mode of green logistics is a new enterprise's logistics operation and management mode concerning environment issues based on the traditional integrated mode. Through comparative study on the integrated operation mode of logistics based on self-operation, the operation mode of an integrated logistics of enterprises based on TPL, the green-supply chain management, and the operation mode of eco-industrial park (EIP), a relatively complete objective system structure is put forward for the integrated operation mode of green logistics of enterprises. Furthermore, the correspondent practical mode is also set up to help enterprises, especially for the manufacturing companies, not only improve the environment effectively, but support the technological framework for the enterprise's economic performance and social benefits in order to realize economic, social and environmental benefits are concerned.

  16. Integrated Weed Control for Land Stewardship at Legacy Management's Rocky Flats Site in Colorado - 13086

    International Nuclear Information System (INIS)

    Nelson, Jody K.

    2013-01-01

    Land stewardship is one of nine sustainability programs in the U.S. Department of Energy's Environmental Management System. Land stewardship includes maintaining and improving ecosystem health. At the Rocky Flats Site near Westminster, Colorado, land stewardship is an integral component of the Office of Legacy Management's post-closure monitoring and management at the site. Nearly 263 hectares (650 acres) were disturbed and re-vegetated during site cleanup and closure operations. Proactive management of revegetation areas is critical to the successful reestablishment of native grasslands, wetlands, and riparian communities. The undisturbed native plant communities that occur at the site also require active management to maintain the high-quality wetlands and other habitats that are home to numerous species of birds and other wildlife such as elk and deer, rare plant communities, and the federally listed threatened Preble's meadow jumping mouse. Over the past several decades, an increase of Noxious weeds has impacted much of Colorado's Front Range. As a result, weed control is a key component of the land stewardship program at Rocky Flats. Thirty-three species of state-listed Noxious weeds are known to occur in the Central and Peripheral Operable Units at Rocky Flats, along with another five species that are considered invasive at the site. Early detection and rapid response to control new invasive species is crucial to the program. An integrated weed control/vegetation management approach is key to maintaining healthy, sustainable plant communities that are able to resist Noxious weed invasions. Weed mapping, field surveys, and field-staff training sessions (to learn how to identify new potential problem species) are conducted to help detect and prevent new weed problems. The integrated approach at Rocky Flats includes administrative and cultural techniques (prevention), mechanical controls, biological controls, and chemical controls. Several species of biocontrol

  17. Computer-aided operations engineering with integrated models of systems and operations

    Science.gov (United States)

    Malin, Jane T.; Ryan, Dan; Fleming, Land

    1994-01-01

    CONFIG 3 is a prototype software tool that supports integrated conceptual design evaluation from early in the product life cycle, by supporting isolated or integrated modeling, simulation, and analysis of the function, structure, behavior, failures and operation of system designs. Integration and reuse of models is supported in an object-oriented environment providing capabilities for graph analysis and discrete event simulation. Integration is supported among diverse modeling approaches (component view, configuration or flow path view, and procedure view) and diverse simulation and analysis approaches. Support is provided for integrated engineering in diverse design domains, including mechanical and electro-mechanical systems, distributed computer systems, and chemical processing and transport systems. CONFIG supports abstracted qualitative and symbolic modeling, for early conceptual design. System models are component structure models with operating modes, with embedded time-related behavior models. CONFIG supports failure modeling and modeling of state or configuration changes that result in dynamic changes in dependencies among components. Operations and procedure models are activity structure models that interact with system models. CONFIG is designed to support evaluation of system operability, diagnosability and fault tolerance, and analysis of the development of system effects of problems over time, including faults, failures, and procedural or environmental difficulties.

  18. Retroviral DNA integration: viral and cellular determinants of target-site selection.

    Directory of Open Access Journals (Sweden)

    Mary K Lewinski

    2006-06-01

    Full Text Available Retroviruses differ in their preferences for sites for viral DNA integration in the chromosomes of infected cells. Human immunodeficiency virus (HIV integrates preferentially within active transcription units, whereas murine leukemia virus (MLV integrates preferentially near transcription start sites and CpG islands. We investigated the viral determinants of integration-site selection using HIV chimeras with MLV genes substituted for their HIV counterparts. We found that transferring the MLV integrase (IN coding region into HIV (to make HIVmIN caused the hybrid to integrate with a specificity close to that of MLV. Addition of MLV gag (to make HIVmGagmIN further increased the similarity of target-site selection to that of MLV. A chimeric virus with MLV Gag only (HIVmGag displayed targeting preferences different from that of both HIV and MLV, further implicating Gag proteins in targeting as well as IN. We also report a genome-wide analysis indicating that MLV, but not HIV, favors integration near DNase I-hypersensitive sites (i.e., +/- 1 kb, and that HIVmIN and HIVmGagmIN also favored integration near these features. These findings reveal that IN is the principal viral determinant of integration specificity; they also reveal a new role for Gag-derived proteins, and strengthen models for integration targeting based on tethering of viral IN proteins to host proteins.

  19. SITE-94. Discrete-feature modelling of the Aespoe site: 2. Development of the integrated site-scale model

    International Nuclear Information System (INIS)

    Geier, J.E.

    1996-12-01

    A 3-dimensional, discrete-feature hydrological model is developed. The model integrates structural and hydrologic data for the Aespoe site, on scales ranging from semi regional fracture zones to individual fractures in the vicinity of the nuclear waste canisters. Hydrologic properties of the large-scale structures are initially estimated from cross-hole hydrologic test data, and automatically calibrated by numerical simulation of network flow, and comparison with undisturbed heads and observed drawdown in selected cross-hole tests. The calibrated model is combined with a separately derived fracture network model, to yield the integrated model. This model is partly validated by simulation of transient responses to a long-term pumping test and a convergent tracer test, based on the LPT2 experiment at Aespoe. The integrated model predicts that discharge from the SITE-94 repository is predominantly via fracture zones along the eastern shore of Aespoe. Similar discharge loci are produced by numerous model variants that explore uncertainty with regard to effective semi regional boundary conditions, hydrologic properties of the site-scale structures, and alternative structural/hydrological interpretations. 32 refs

  20. SITE-94. Discrete-feature modelling of the Aespoe site: 2. Development of the integrated site-scale model

    Energy Technology Data Exchange (ETDEWEB)

    Geier, J.E. [Golder Associates AB, Uppsala (Sweden)

    1996-12-01

    A 3-dimensional, discrete-feature hydrological model is developed. The model integrates structural and hydrologic data for the Aespoe site, on scales ranging from semi regional fracture zones to individual fractures in the vicinity of the nuclear waste canisters. Hydrologic properties of the large-scale structures are initially estimated from cross-hole hydrologic test data, and automatically calibrated by numerical simulation of network flow, and comparison with undisturbed heads and observed drawdown in selected cross-hole tests. The calibrated model is combined with a separately derived fracture network model, to yield the integrated model. This model is partly validated by simulation of transient responses to a long-term pumping test and a convergent tracer test, based on the LPT2 experiment at Aespoe. The integrated model predicts that discharge from the SITE-94 repository is predominantly via fracture zones along the eastern shore of Aespoe. Similar discharge loci are produced by numerous model variants that explore uncertainty with regard to effective semi regional boundary conditions, hydrologic properties of the site-scale structures, and alternative structural/hydrological interpretations. 32 refs.

  1. Rocketdyne Propulsion & Power DOE Operations Annual Site Environmental Report 1996

    Energy Technology Data Exchange (ETDEWEB)

    Tuttle, R. J. [The Boeing Company, Canoga Park, CA (United States)

    1997-11-10

    This annual report discusses environmental monitoring at two manufacturing and test operations sites operated in the Los Angeles area by Rocketdyne Propulsion & Power of Boeing North American. Inc. (formerly Rockwell International Corporation). These are identified as the Santa Susana Field Laboratory (SSFL and the De Soto site. The sites have been used for manufacturing; R&D, engineering, and testing in a broad range of technical fields, primarily rocket engine propulsion and nuclear reactor technology. The De Soto site essentially comprises office space and light industry with no remaining radiological operations, and has little potential impact on the environment. The SSFL site, because of its large size (2.668 acres), warrants comprehensive monitoring to ensure protection of the environment.

  2. An integrated approach to site selection for nuclear power plants

    International Nuclear Information System (INIS)

    Hassan, E.M.A.

    1975-01-01

    A method of analysing and evaluating the large number of factors influencing site selection is proposed, which can interrelate these factors and associated problems in an integrated way and at the same time establish a technique for site evaluation. The objective is to develop an integrated programme that illustrates the complexity and dynamic interrelationships of the various factors to develop an improved understanding of the functions and objectives of siting nuclear power plants and would aim finally at the development of an effective procedure and technique for site evaluation and/or comparative evaluation for making rational site-selection decisions. (author)

  3. GMRES and integral operators

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, C.T.; Xue, Z.Q. [North Carolina State Univ., Raleigh, NC (United States)

    1994-12-31

    Many discretizations of integral equations and compact fixed point problems are collectively compact and strongly convergent in spaces of continuous functions. These properties not only lead to stable and convergent approximations but also can be used in the construction of fast multilevel algorithms. Recently the GMRES algorithm has become a standard coarse mesh solver. The purpose of this paper is to show how the special properties of integral operators and their approximations are reflected in the performance of the GMRES iteration and how these properties can be used to strengthen the norm in which convergence takes place. The authors illustrate these ideas with composite Gauss rules for integral equations on the unit interval.

  4. Integrated Site Model Process Model Report

    International Nuclear Information System (INIS)

    Booth, T.

    2000-01-01

    The Integrated Site Model (ISM) provides a framework for discussing the geologic features and properties of Yucca Mountain, which is being evaluated as a potential site for a geologic repository for the disposal of nuclear waste. The ISM is important to the evaluation of the site because it provides 3-D portrayals of site geologic, rock property, and mineralogic characteristics and their spatial variabilities. The ISM is not a single discrete model; rather, it is a set of static representations that provide three-dimensional (3-D), computer representations of site geology, selected hydrologic and rock properties, and mineralogic-characteristics data. These representations are manifested in three separate model components of the ISM: the Geologic Framework Model (GFM), the Rock Properties Model (RPM), and the Mineralogic Model (MM). The GFM provides a representation of the 3-D stratigraphy and geologic structure. Based on the framework provided by the GFM, the RPM and MM provide spatial simulations of the rock and hydrologic properties, and mineralogy, respectively. Functional summaries of the component models and their respective output are provided in Section 1.4. Each of the component models of the ISM considers different specific aspects of the site geologic setting. Each model was developed using unique methodologies and inputs, and the determination of the modeled units for each of the components is dependent on the requirements of that component. Therefore, while the ISM represents the integration of the rock properties and mineralogy into a geologic framework, the discussion of ISM construction and results is most appropriately presented in terms of the three separate components. This Process Model Report (PMR) summarizes the individual component models of the ISM (the GFM, RPM, and MM) and describes how the three components are constructed and combined to form the ISM

  5. Univalence Conditions Related to a General Integral Operator

    Directory of Open Access Journals (Sweden)

    Nicoleta Breaz

    2012-01-01

    Full Text Available We consider a general integral operator based on two types of analytic functions, namely, regular functions and, respectively, functions having a positive real part. Some univalence conditions for this integral operator are obtained.

  6. On Univalence Criteria for a General Integral Operator

    Directory of Open Access Journals (Sweden)

    Vasile Marius Macarie

    2012-01-01

    Full Text Available We consider a new general integral operator, and we give sufficient conditions for the univalence of this integral operator in the open unit disk of the complex plane. Several consequences of the main results are also shown.

  7. Containment long-term operational integrity

    International Nuclear Information System (INIS)

    Sammataro, R.F.

    1990-01-01

    Periodic integrated leak rate tests are required to assure that containments continue to meet allowable leakage limits. Although overall performance has been quite good to date, several major containment aging and degradation mechanisms have been identified. Two pilot plant life extension (PLEX) studies serve as models for extending the operational integrity of present containments for light-water cooled nuclear power plants in the United States. One study is for a Boiling-Water Reactor (BWR) and the second is for a Pressurized-Water Reactor (PWR). Research and testing programs for determining the ultimate pressure capacity and failure mechanisms for containments under severe loading conditions and studies for extending the life of current plants beyond the present 40-year licensed lifetime are under way. This paper presents an overview of containment designs in the United States. Also presented are a discussion of the American Society of Mechanical Engineers Boiler and Pressure Vessel Code (ASME Code) and regulatory authority requirements for the design, construction, inservice inspection, leakage testing and repair of steel and concrete containments. Findings for containments from the pilot PLEX studies and continuing containment integrity research and testing programs are discussed. The ASME Code and regulatory requirements together with recommendations from the PLEX studies and containment integrity research and testing provide a basis for continued containment long-term operational integrity. (orig./GL)

  8. TTP AL921102: An integrated geophysics program for non-intrusive characterization of mixed-waste landfill sites

    International Nuclear Information System (INIS)

    Hasbrouck, J.C.

    1992-11-01

    Chem-Nuclear Geotech, Inc. (Geotech), operating contractor for the US Department of Energy Grand Junction Projects Office, is conducting the Integrated Geophysics Program for Non-Intrusive Characterization of Mixed-Waste Landfill Sites (Technical Task Plan [TTP] AL921102). The TTP is part of the Mixed-Waste Landfill Integrated Demonstration (MWLID). The objective of this task was to demonstrate that an integrated program of surface geophysics can be used to effectively and nonintrusively characterize n-mixed-waste landfill sites. To accomplish this objective, integrated field demonstrations were conducted over two previously identified areas of interest (designated Areas A and B) within the MWLID test site at the Chemical Waste Landfill (CWL), Technical Area 3, at the Sandia National Laboratories, Albuquerque, New Mexico (Figures 1 and 2). Area A was centered roughly around the Chromic Acid and Organics Pits in the southeast-central portion of the landfill and Area B was centered around the ''60's Pits'' area in the northeast-central portion of the landfill. Pit locations were known in Area A and suspected in Area B. This progress report describes the geophysical surveys conducted by Geotech and presents preliminary displays and analyses. Volume 2 of this report contains the raw data for all the surveys conducted by Geotech for this TTP

  9. Lessons learned in the implementation of Integrated Safety Management at DOE Order Compliance Sites vs Necessary and Sufficient Sites

    International Nuclear Information System (INIS)

    Hill, R.L.

    2000-01-01

    This paper summarizes the development and implementation of Integrated Safety Management (ISM) at an Order Compliance Site (Savannah River Site) and a Necessary and Sufficient Site (Nevada Test Site). A discussion of each core safety function of ISM is followed by an example from an Order Compliance Site and a Necessary and Sufficient Site. The Savannah River Site was the first DOE site to have a DOE Headquarters-validated and approved ISM System. The NTS is beginning the process of verification and validation. This paper defines successful strategies for integrating Environment, Safety, and Health management into work under various scenarios

  10. AUTOCAD IN THE OPERATIONAL MANAGEMENT OF THE CONSTRUCTION SITE

    Directory of Open Access Journals (Sweden)

    Tsareva Marina Vladimirovna

    2016-04-01

    Full Text Available Operational management of the construction is usually based on information analysis systems, which are aimed at the monitoring of working schedule and volumes as consistent with predicated schedules. The result of such systems’ operation is traditional information graphics (diagrams, charts, etc., which provides idea on the current state of the construction site and deviations from the planned settings. The author considers the visualization technology of construction of objects using an image of the situation on the AutoCAD drawings, converted into an interactive format. The article focuses on imperfections of the existing technologies of information support of the managers. The creation of unified IT platform is offered on the basis of CAD for creating an integrated information storage and visualization of the environment using electronic drawings and diagrams. Using interactive methods it is possible to illustrate the condition of almost any part of the construction project using these drawings and diagrams. E-drawings contain the basic information resources - estimates, plans, sections, specifications, technology, construction, etc. necessary for the calculation of indicators. The author proved that implementation of visualization is most efficient in case of electronic drawings in 3D format.

  11. Integrated operations plan for the MFTF-B Mirror Fusion Test Facility. Volume II. Integrated operations plan

    Energy Technology Data Exchange (ETDEWEB)

    1981-12-01

    This document defines an integrated plan for the operation of the Lawrence Livermore National Laboratory (LLNL) Mirror Fusion Test Facility (MFTF-B). The plan fulfills and further delineates LLNL policies and provides for accomplishing the functions required by the program. This plan specifies the management, operations, maintenance, and engineering support responsibilities. It covers phasing into sustained operations as well as the sustained operations themselves. Administrative and Plant Engineering support, which are now being performed satisfactorily, are not part of this plan unless there are unique needs.

  12. Integrated operations plan for the MFTF-B Mirror Fusion Test Facility. Volume II. Integrated operations plan

    International Nuclear Information System (INIS)

    1981-12-01

    This document defines an integrated plan for the operation of the Lawrence Livermore National Laboratory (LLNL) Mirror Fusion Test Facility (MFTF-B). The plan fulfills and further delineates LLNL policies and provides for accomplishing the functions required by the program. This plan specifies the management, operations, maintenance, and engineering support responsibilities. It covers phasing into sustained operations as well as the sustained operations themselves. Administrative and Plant Engineering support, which are now being performed satisfactorily, are not part of this plan unless there are unique needs

  13. Integrated safety analysis to operate while constructing Urenco USA

    International Nuclear Information System (INIS)

    Kohrt, Rick; Su, Shiaw-Der; Lehman, Richard

    2013-01-01

    The URENCO USA (UUSA) site in Lea County, New Mexico, USA is authorized by the U.S. Nuclear Regulatory Commission (NRC) for construction and operation of a uranium enrichment facility under 10 CFR 70 (Ref 1). The facility employs the gas centrifuge process to separate natural uranium hexafluoride (UF 6 ) feed material into a product stream enriched up to 5% U-235 and a depleted UF 6 stream containing approximately 0.2 to 0.34% U-235. Initial plant operations, with a limited number of cascades on line, commenced in the second half of 2010. Construction activities continue as each subsequent cascade is commissioned and placed into service. UUSA performed an Integrated Safety Analysis (ISA) to allow the facility to operate while constructing the remainder of the facility. The ISA Team selected the What-If/Checklist method based on guidance in NUREG-1513 (Ref 2) and AIChE Guidelines (Ref 3). Of the three methods recommended for high risk events HAZOP, What-If/Checklist, or Failure Modes and Effects Analysis (FMEA), the What-If/Checklist lends itself best to construction activities. It combines the structure of a checklist with an unstructured 'brainstorming' approach to create a list of specific accident events that could produce an undesirable consequence. The What-If/Checklist for Operate While Constructing divides the UUSA site into seven areas and creates what-if questions for sixteen different construction activities, such as site preparation, external construction cranes, and internal construction lifts. The result is a total of 112 nodes, for which the Operate While Constructing ISA Team created hundreds of what-if questions. For each what-if question the team determined the likelihood, consequences, safeguards, and acceptability of risk. What-if questions with unacceptable risk are the accident sequences and their selected safeguards are the Items Relied on For Safety (IROFS). The final ISA identified four (4) new accident sequences that, unless

  14. Integrated Ground Operations Demonstration Units Testing Plans and Status

    Science.gov (United States)

    Johnson, Robert G.; Notardonato, William U.; Currin, Kelly M.; Orozco-Smith, Evelyn M.

    2012-01-01

    Cryogenic propellant loading operations with their associated flight and ground systems are some of the most complex, critical activities in launch operations. Consequently, these systems and operations account for a sizeable portion of the life cycle costs of any launch program. NASA operations for handling cryogens in ground support equipment have not changed substantially in 50 years, despite advances in cryogenics, system health management and command and control technologies. This project was developed to mature, integrate and demonstrate advancement in the current state of the art in these areas using two distinct integrated ground operations demonstration units (GODU): GODU Integrated Refrigeration and Storage (IRAS) and GODU Autonomous Control

  15. Integrated Weed Control for Land Stewardship at Legacy Management's Rocky Flats Site in Colorado - 13086

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Jody K. [Stoller LMS Team, Contractor to the U.S. Department of Energy Office of Legacy Management, 11025 Dover Street, Suite 1000, Westminster, Colorado 80021 (United States)

    2013-07-01

    Land stewardship is one of nine sustainability programs in the U.S. Department of Energy's Environmental Management System. Land stewardship includes maintaining and improving ecosystem health. At the Rocky Flats Site near Westminster, Colorado, land stewardship is an integral component of the Office of Legacy Management's post-closure monitoring and management at the site. Nearly 263 hectares (650 acres) were disturbed and re-vegetated during site cleanup and closure operations. Proactive management of revegetation areas is critical to the successful reestablishment of native grasslands, wetlands, and riparian communities. The undisturbed native plant communities that occur at the site also require active management to maintain the high-quality wetlands and other habitats that are home to numerous species of birds and other wildlife such as elk and deer, rare plant communities, and the federally listed threatened Preble's meadow jumping mouse. Over the past several decades, an increase of Noxious weeds has impacted much of Colorado's Front Range. As a result, weed control is a key component of the land stewardship program at Rocky Flats. Thirty-three species of state-listed Noxious weeds are known to occur in the Central and Peripheral Operable Units at Rocky Flats, along with another five species that are considered invasive at the site. Early detection and rapid response to control new invasive species is crucial to the program. An integrated weed control/vegetation management approach is key to maintaining healthy, sustainable plant communities that are able to resist Noxious weed invasions. Weed mapping, field surveys, and field-staff training sessions (to learn how to identify new potential problem species) are conducted to help detect and prevent new weed problems. The integrated approach at Rocky Flats includes administrative and cultural techniques (prevention), mechanical controls, biological controls, and chemical controls. Several

  16. Elements of an advanced integrated operator control station

    International Nuclear Information System (INIS)

    Clarke, M.M.; Kreifeldt, J.G.

    1984-01-01

    One of the critical determinants of peformance for any remotely operated maintenance system is the compatibility achieved between elements of the man/machine interface (e.g., master manipulator controller, controls, displays, etc.) and the human operator. In the Remote Control Engineering task of the Consolidated Fuel Reprocessing Program, considerable attention has been devoted to optimizing the man/machine interface of the operator control station. This system must be considered an integral element of the overall maintenance work system which includes transporters, manipulators, remote viewing, and other parts. The control station must reflect the integration of the operator team, control/display panels, manipulator master controllers, and remote viewing monitors. Human factors principles and experimentation have been used in the development of an advanced integrated operator control station designed for the advance servomanipulator. Key features of this next-generation design are summarized in this presentation. 7 references, 4 figures

  17. Elements of an advanced integrated operator control station

    International Nuclear Information System (INIS)

    Clarke, M.M.; Kreifeldt, J.G.

    1984-01-01

    One of the critical determinants of performance for any remotely operated maintenance system is the compatibility achieved between elements of the man/machine interface (e.g., master manipulator controller, controls, displays) and the human operator. In the remote control engineering task of the Consolidated Fuel Reprocessing Program, considerable attention has been devoted to optimizing the man/machine interface of the operator control station. This system must be considered an integral element of the overall maintenance work system which includes transporters, manipulators, remote viewing, and other parts. The control station must reflect the integration of the operator team, control/display panels, manipulator master controllers, and remote viewing monitors. Human factors principles and experimentation have been used in the development of an advanced integrated operator control station designed for the advance servomanipulator. Key features of this next-generation design are summarized in this presentation. 7 references, 4 figures

  18. Demonstration of Eastman Christensen horizontal drilling system -- Integrated Demonstration Site, Savannah River Site

    International Nuclear Information System (INIS)

    1992-12-01

    An innovative horizontal drilling system was used to install two horizontal wells as part of an integrated demonstration project at the Savannah River Site (SRS), Aiken, South Carolina. The SRS is located in south-central South Carolina in the upper Coastal Plain physiographic province. The demonstration site is located near the A/M Area, and is currently known as the Integated Demonstration Site. The Department of Energy's Office of Technology Development initiated an integrated demonstration of innovative technologies for cleanup of volatile organic compounds (VOCS) in soils and groundwater at the SRS in 1989. The overall goal of the program is to demonstrate, at a single location, multiple technologies in the fields of drilling, characterization, monitoring, and remediation. Innovative technologies are compared to one another and to baseline technologies in terms of technical performance and cost effectiveness. Transfer of successfully demonstrated technologies and systems to DOE environmental restoration organizations, to other government agencies, and to industry is a critical part of the program

  19. Integrated environmental monitoring program at the Hanford Site

    International Nuclear Information System (INIS)

    Jaquish, R.E.

    1990-08-01

    The US Department of Energy's Hanford Site, north of Richland, Washington, has a mission of defense production, waste management, environmental restoration, advanced reactor design, and research development. Environmental programs at Hanford are conducted by Pacific Northwest Laboratory (PNL) and the Westinghouse Hanford Company (WHC). The WHC environmental programs include the compliance and surveillance activities associated with site operations and waste management. The PNL environmental programs address the site-wide and the of-site areas. They include the environmental surveillance and the associated support activities, such as dose calculations, and also the monitoring of environmental conditions to comply with federal and state environmental regulations on wildlife and cultural resources. These are called ''independent environmental programs'' in that they are conducted completely separate from site operations. The Environmental Surveillance and Oversight Program consists of the following projects: surface environmental surveillance; ground-water surveillance; wildlife resources monitoring; cultural resources; dose overview; radiation standards and calibrations; meteorological and climatological services; emergency preparedness

  20. Surgical site infections in paediatric otolaryngology operative procedures.

    Science.gov (United States)

    Ifeacho, S N; Bajaj, Y; Jephson, C G; Albert, D M

    2012-07-01

    An assessment of the rate of surgical site infections associated with elective paediatric otolaryngology surgical procedures. Prospective data was collected for a 3-week period for all children undergoing surgery where either mucosa or skin was breached. The parents of the children were requested to complete a questionnaire at 30 days after the operation. Data was collected on 80 consecutive cases. The majority of cases were admitted on the day of the procedure. The procedures included adenotonsillectomy (24), grommets (12), cochlear implantation (6), bone-anchored hearing aid (2), submandibular gland excision (1), branchial sinus excision (1), cystic hygroma excision (3), nasal glioma excision (1), microlaryngobronchoscopy (13), tracheostomy (3) and other procedures (14). Nearly half the cases had more than one operation done at the same time. 26/80 (32.5%) patients had a temporary or permanent implant inserted at the time of operation (grommet, bone-anchored hearing aid, cochlear implant). 25/80 (31%) operative fields were classed as clean and 55/80 (68.7%) as clean contaminated operations. The duration of the operation varied from 6 min to 142 min. Hospital antibiotic protocol was adhered to in 69/80 (86.3%) cases but not in 11/80 cases. In our series, 3/80 (3.7%) patients had an infection in the postoperative period. Surgical site infections do occur at an appreciable rate in paediatric otolaryngology. With the potential for serious consequences, reduction in the risk of surgical site infections is important. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  1. Non-Operational Property Evaluation for the Hanford Site River Corridor - 12409

    Energy Technology Data Exchange (ETDEWEB)

    Lowe, John [CH2M HILL, Richland, Washington 99354 (United States); Aly, Alaa [CH2M HILL Plateau Remediation Company and INTERA Incorporated, Richland, Washington 99354 (United States)

    2012-07-01

    The Hanford Site River Corridor consists of the former reactor areas of the 100 Areas and the former industrial (fuel processing) area in the 300 Area. Most of the waste sites are located close to the decommissioned reactors or former industrial facilities along the Columbia River. Most of the surface area of the River Corridor consists of land with little or no subsurface infrastructure or indication of past or present releases of hazardous constituents, and is referred to as non-operational property or non-operational area. Multiple lines of evidence have been developed to assess identified fate and transport mechanisms and to evaluate the potential magnitude and significance of waste site-related contaminants in the non-operational area. Predictive modeling was used for determining the likelihood of locating waste sites and evaluating the distribution of radionuclides in soil based on available soil concentration data and aerial radiological surveys. The results of this evaluation indicated: 1) With the exception of stack emissions, transport pathways associated with waste site contaminants are unlikely to result in dispersion of contaminants in soil away from operational areas, 2) Stack emissions that may have been associated with Hanford Site operations generally emitted short-lived and/or gaseous radionuclides, and (3) the likelihood of detecting elevated radionuclide concentrations or other waste sites in non-operational area soils is very small. The overall conclusions from the NPE evaluation of the River Corridor are: - With the exception of stack emissions to the air, transport pathways associated with waste site contaminants are unlikely to result in dispersion of contaminants in soil away from operational areas. While pathways such as windblown dust, overland transport and biointrusion have the potential for dispersing waste site contaminants, the resulting transport is unlikely to result in substantial contamination in non-operational areas. - Stack

  2. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences.

    Directory of Open Access Journals (Sweden)

    Rick S Mitchell

    2004-08-01

    Full Text Available The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report an analysis of 3,127 integration site sequences from human cells. We compared retroviral vectors derived from human immunodeficiency virus (HIV, avian sarcoma-leukosis virus (ASLV, and murine leukemia virus (MLV. Effects of gene activity on integration targeting were assessed by transcriptional profiling of infected cells. Integration by HIV vectors, analyzed in two primary cell types and several cell lines, strongly favored active genes. An analysis of the effects of tissue-specific transcription showed that it resulted in tissue-specific integration targeting by HIV, though the effect was quantitatively modest. Chromosomal regions rich in expressed genes were favored for HIV integration, but these regions were found to be interleaved with unfavorable regions at CpG islands. MLV vectors showed a strong bias in favor of integration near transcription start sites, as reported previously. ASLV vectors showed only a weak preference for active genes and no preference for transcription start regions. Thus, each of the three retroviruses studied showed unique integration site preferences, suggesting that virus-specific binding of integration complexes to chromatin features likely guides site selection.

  3. OPERATIONS REVIEW OF THE SAVANNAH RIVER SITE INTEGRATED SALT DISPOSITION PROCESS - 11327

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T.; Poirier, M.; Fondeur, F.; Fink, S.; Brown, S.; Geeting, M.

    2011-02-07

    The Savannah River Site (SRS) is removing liquid radioactive waste from its Tank Farm. To treat waste streams that are low in Cs-137, Sr-90, and actinides, SRS developed the Actinide Removal Process and implemented the Modular Caustic Side Solvent Extraction (CSSX) Unit (MCU). The Actinide Removal Process contacts salt solution with monosodium titanate to sorb strontium and select actinides. After monosodium titanate contact, the resulting slurry is filtered to remove the monosodium titanate (and sorbed strontium and actinides) and entrained sludge. The filtrate is transferred to the MCU for further treatment to remove cesium. The solid particulates removed by the filter are concentrated to {approx} 5 wt %, washed to reduce the sodium concentration, and transferred to the Defense Waste Processing Facility for vitrification. The CSSX process extracts the cesium from the radioactive waste using a customized solvent to produce a Decontaminated Salt Solution (DSS), and strips and concentrates the cesium from the solvent with dilute nitric acid. The DSS is incorporated in grout while the strip acid solution is transferred to the Defense Waste Processing Facility for vitrification. The facilities began radiological processing in April 2008 and started processing of the third campaign ('MarcoBatch 3') of waste in June 2010. Campaigns to date have processed {approx}1.2 million gallons of dissolved saltcake. Savannah River National Laboratory (SRNL) personnel performed tests using actual radioactive samples for each waste batch prior to processing. Testing included monosodium titanate sorption of strontium and actinides followed by CSSX batch contact tests to verify expected cesium mass transfer. This paper describes the tests conducted and compares results from facility operations. The results include strontium, plutonium, and cesium removal, cesium concentration, and organic entrainment and recovery data. Additionally, the poster describes lessons learned during

  4. Application of the Integrated Site and Environment Data Management System for LILW Disposal Site

    International Nuclear Information System (INIS)

    Lee, Ji Hoon; Lee, Eun Yong; Kim, Chang Lak

    2007-01-01

    During the last five years, Site Information and Total Environmental data management System(SITES) has been developed. SITES is an integrated program for overall data acquisition, environmental monitoring, and safety analysis. SITES is composed of three main modules, such as site database system (SECURE), safety assessment system (SAINT) and environmental monitoring system (SUDAL). In general, for the safe management of radioactive waste repository, the information of site environment should be collected and managed systematically from the initial site survey. For this, SECURE module manages its data for the site characterization, environmental information, and radioactive environmental information etc. The purpose of SAINT module is to apply and analyze the data from SECURE. SUDAL is developed for environmental monitoring of the radioactive waste repository. Separately, it is ready to open to the public for offering partial information

  5. Modification site localization scoring integrated into a search engine.

    Science.gov (United States)

    Baker, Peter R; Trinidad, Jonathan C; Chalkley, Robert J

    2011-07-01

    Large proteomic data sets identifying hundreds or thousands of modified peptides are becoming increasingly common in the literature. Several methods for assessing the reliability of peptide identifications both at the individual peptide or data set level have become established. However, tools for measuring the confidence of modification site assignments are sparse and are not often employed. A few tools for estimating phosphorylation site assignment reliabilities have been developed, but these are not integral to a search engine, so require a particular search engine output for a second step of processing. They may also require use of a particular fragmentation method and are mostly only applicable for phosphorylation analysis, rather than post-translational modifications analysis in general. In this study, we present the performance of site assignment scoring that is directly integrated into the search engine Protein Prospector, which allows site assignment reliability to be automatically reported for all modifications present in an identified peptide. It clearly indicates when a site assignment is ambiguous (and if so, between which residues), and reports an assignment score that can be translated into a reliability measure for individual site assignments.

  6. Certain Inequalities Involving the Fractional q-Integral Operators

    Directory of Open Access Journals (Sweden)

    Dumitru Baleanu

    2014-01-01

    Full Text Available We establish some inequalities involving Saigo fractional q-integral operator in the theory of quantum calculus by using the two parameters of deformation, q1 and q2, whose special cases are shown to yield corresponding inequalities associated with Riemann-Liouville and Kober fractional q-integral operators, respectively. Furthermore, we also consider their relevance with other related known results.

  7. Space station operations task force. Panel 4 report: Management integration

    Science.gov (United States)

    1987-01-01

    The Management Integration Panel of the Space Station Operations Task Force was chartered to provide a structure and ground rules for integrating the efforts of the other three panels and to address a number of cross cutting issues that affect all areas of space station operations. Issues addressed include operations concept implementation, alternatives development and integration process, strategic policy issues and options, and program management emphasis areas.

  8. Some criteria for two new integral operators

    Directory of Open Access Journals (Sweden)

    Laura Stanciu

    2012-12-01

    Full Text Available Using the Hadamard product, we define two new integral operators. The main object of the present paper is to discuss some univalence conditions for these operators. Several corollaries of the main results are also considered.

  9. Projection operator and propagator for an arbitrary integral spin

    CERN Document Server

    Huang Shi Zhong; Wu Ning; Zheng Zhi Peng

    2002-01-01

    Based on the solution of the Bargmann-Wigner equation for an arbitrary integral spin, a direct derivation of the projection operator and propagator for an arbitrary integral spin is presented. The explicit form for the spin projection operators constructed by Behrends and Fronsdal is confirmed. The commutation rules and a general expression for the Feynman propagator for a free particle of arbitrary integral spin are deduced

  10. [Comprehensive system integration and networking in operating rooms].

    Science.gov (United States)

    Feußner, H; Ostler, D; Kohn, N; Vogel, T; Wilhelm, D; Koller, S; Kranzfelder, M

    2016-12-01

    A comprehensive surveillance and control system integrating all devices and functions is a precondition for realization of the operating room of the future. Multiple proprietary integrated operation room systems are currently available with a central user interface; however, they only cover a relatively small part of all functionalities. Internationally, there are at least three different initiatives to promote a comprehensive systems integration and networking in the operating room: the Japanese smart cyber operating theater (SCOT), the American medical device plug-and-play interoperability program (MDPnP) and the German secure and dynamic networking in operating room and hospital (OR.NET) project supported by the Federal Ministry of Education and Research. Within the framework of the internationally advanced OR.NET project, prototype solution approaches were realized, which make short-term and mid-term comprehensive data retrieval systems probable. An active and even autonomous control of the medical devices by the surveillance and control system (closed loop) is expected only in the long run due to strict regulatory barriers.

  11. Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Potable Water System Operations Plan

    Energy Technology Data Exchange (ETDEWEB)

    Ocampo, Ruben P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bellah, Wendy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-03-04

    The existing Lawrence Livermore National Laboratory (LLNL) Site 300 drinking water system operation schematic is shown in Figures 1 and 2 below. The sources of water are from two Site 300 wells (Well #18 and Well #20) and San Francisco Public Utilities Commission (SFPUC) Hetch-Hetchy water through the Thomas shaft pumping station. Currently, Well #20 with 300 gallons per minute (gpm) pump capacity is the primary source of well water used during the months of September through July, while Well #18 with 225 gpm pump capacity is the source of well water for the month of August. The well water is chlorinated using sodium hypochlorite to provide required residual chlorine throughout Site 300. Well water chlorination is covered in the Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Chlorination Plan (“the Chlorination Plan”; LLNL-TR-642903; current version dated August 2013). The third source of water is the SFPUC Hetch-Hetchy Water System through the Thomas shaft facility with a 150 gpm pump capacity. At the Thomas shaft station the pumped water is treated through SFPUC-owned and operated ultraviolet (UV) reactor disinfection units on its way to Site 300. The Thomas Shaft Hetch- Hetchy water line is connected to the Site 300 water system through the line common to Well pumps #18 and #20 at valve box #1.

  12. Surgical Site Infections and Associated Operative Characteristics.

    Science.gov (United States)

    Waltz, Paul K; Zuckerbraun, Brian S

    Surgical site infection (SSI) contributes significantly to surgical morbidity. Patient factors and operative factors contribute to the risk of development of SSI. This review focuses on understanding operative characteristics that are associated with an increased risk of SSI. Much attention has been given to protocol care to reduce SSI, such as hair removal, skin preparation, and pre-operative antibiotic agents. Even with this, the appropriate antibiotic and re-dosing regimens often remain a challenge. Other operative factors such as blood loss/transfusion, emergency/urgent cases, duration of the operation, type of anesthesia, and resident involvement are also potentially modifiable to reduce the risk of SSI. Data are reviewed to highlight the increased risk associated with such factors. Strategies to reduce risk, such as operative care bundles, have significant promise to reduce the incidence of SSI for any given procedure.

  13. DNFSB recommendation 94-1 Hanford site integrated stabilization management plan

    Energy Technology Data Exchange (ETDEWEB)

    McCormack, R.L.

    1997-05-07

    In May 1994, the Defense Nuclear Facilities Safety Board (DNFSB) issued DNFSB Recommendation 94-1 (Conway 1994), which identified concerns related to US Department of Energy (DOE) management of legacy fissile materials remaining from past defense production activities. The DNFSB expressed concern about the existing storage conditions for these materials and the slow pace at which the conditions were being remediated. The DNFSB also expressed its belief that additional delays in stabilizing these fissile materials would be accompanied by further deterioration of safety and unnecessary increased risks to workers and the public. In February 1995, DOE issued the DNFSB Recommendation 94-1 Implementation Plan (O`Leary 1995) to address the concerns identified in DNFSB Recommendation 94-1. The Implementation Plan (IP) identifies several DOE commitments to achieve safe interim storage for the legacy fissile materials, and constitutes DOE`s baseline DNFSB Recommendation 94-1 Integrated Program Plan (IPP). The IPP describes the actions DOE plans to implement within the DOE complex to convert its excess fissile materials to forms or conditions suitable for safe interim storage. The IPP was subsequently supplemented with an Integrated Facilities Plan and a Research and Development Plan, which further develop complex-wide research and development and long-range facility requirements and plans. The additions to the baseline IPP were developed based on a systems engineering approach that integrated facilities and capabilities at the various DOE sites and focused on attaining safe interim storage with minimum safety risks and environmental impacts. Each affected DOE site has developed a Site Integrated Stabilization Management Plan (SISMP) to identify individual site plans to implement the DNFSB Recommendation 94-1 IPP. The SISMPs were developed based on the objectives, requirements, and commitments identified in the DNFSB Recommendation 94-1 IP. The SISMPs also supported

  14. DNFSB recommendation 94-1 Hanford site integrated stabilization management plan

    International Nuclear Information System (INIS)

    McCormack, R.L.

    1997-01-01

    In May 1994, the Defense Nuclear Facilities Safety Board (DNFSB) issued DNFSB Recommendation 94-1 (Conway 1994), which identified concerns related to US Department of Energy (DOE) management of legacy fissile materials remaining from past defense production activities. The DNFSB expressed concern about the existing storage conditions for these materials and the slow pace at which the conditions were being remediated. The DNFSB also expressed its belief that additional delays in stabilizing these fissile materials would be accompanied by further deterioration of safety and unnecessary increased risks to workers and the public. In February 1995, DOE issued the DNFSB Recommendation 94-1 Implementation Plan (O'Leary 1995) to address the concerns identified in DNFSB Recommendation 94-1. The Implementation Plan (IP) identifies several DOE commitments to achieve safe interim storage for the legacy fissile materials, and constitutes DOE's baseline DNFSB Recommendation 94-1 Integrated Program Plan (IPP). The IPP describes the actions DOE plans to implement within the DOE complex to convert its excess fissile materials to forms or conditions suitable for safe interim storage. The IPP was subsequently supplemented with an Integrated Facilities Plan and a Research and Development Plan, which further develop complex-wide research and development and long-range facility requirements and plans. The additions to the baseline IPP were developed based on a systems engineering approach that integrated facilities and capabilities at the various DOE sites and focused on attaining safe interim storage with minimum safety risks and environmental impacts. Each affected DOE site has developed a Site Integrated Stabilization Management Plan (SISMP) to identify individual site plans to implement the DNFSB Recommendation 94-1 IPP. The SISMPs were developed based on the objectives, requirements, and commitments identified in the DNFSB Recommendation 94-1 IP. The SISMPs also supported

  15. Integration of operational research and environmental management

    NARCIS (Netherlands)

    Bloemhof - Ruwaard, J.M.

    1996-01-01


    The subject of this thesis is the integration of Operational Research and Environmental Management. Both sciences play an important role in the research of environmental issues. Part I describes a framework for the interactions between Operational Research and Environmental Management.

  16. Completely integrable operator evolutionary equations

    International Nuclear Information System (INIS)

    Chudnovsky, D.V.

    1979-01-01

    The authors present natural generalizations of classical completely integrable equations where the functions are replaced by arbitrary operators. Among these equations are the non-linear Schroedinger, the Korteweg-de Vries, and the modified KdV equations. The Lax representation and the Baecklund transformations are presented. (Auth.)

  17. Application for Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site - U10c Disposal Site

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Programs

    2010-08-05

    The NTS is located approximately 105 km (65 mi) northwest of Las Vegas, Nevada. NNSA/NSO is the federal lands management authority for the NTS and NSTec is the Management & Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS is posted with signs along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The U10C Disposal Site is located in the northwest corner of Area 9 at the NTS (Figure 1) and is located in a subsidence crater created by two underground nuclear events, one in October 1962 and another in April 1964. The disposal site opened in 1971 for the disposal of rubbish, refuse, pathological waste, asbestos-containing material, and industrial solid waste. A Notice of Intent form to operate the disposal site as a Class II site was submitted to the state of Nevada on January 26, 1994, and was acknowledged in a letter to the DOE on February 8, 1994. It operated as a state of Nevada Class II Solid Waste Disposal Site (SWDS) until it closed on October 5, 1995, for retrofit as a Class III SWDS. The retrofit consisted of the installation of a minimum four-foot compacted soil layer to segregate the different waste types and function as a liner to inhibit leachate and water flow into the lower waste zone. Five neutron monitoring tubes were installed in this layer to monitor possible leachate production and water activity. Upon acceptance of the installed barrier and approval of an Operating Plan by NDEP/BFF, the site reopened in January 1996 as a Class III SWDS for the disposal of industrial solid waste and other inert waste.

  18. Integration of remotely operated manipulator systems for the nuclear industry

    International Nuclear Information System (INIS)

    Blight, J.; Cornec, G.

    2003-01-01

    rectify the situation. The paper has the following structure: Methodology (choice of scenarios, initial status, final status); Phases preceding dismantling operations; Flux of wastes; Processes; Remotely operated manipulators; Development of scenarios; Involvement of CYBERNETIX in dismantling projects; Involvement in 'Upstream phasest'; Supply of remotely operated systems; Validation of processes and remotely operated systems prior to active work; Involvement at site. As a summary, CYBERNETIX recommends, in order to ensure the good development of a project: - to be actively involved in developing/validating processes and scenarios, in order to make sure that constraints from both the remotely operated systems and the environment are taken into consideration; - to amortize amortization of development, integration, refurbishing, maintenance and storage costs on a serial of works/projects; - to provision sufficient time to develop, adapt, fine-tune equipment and processes, as a function of the scenarios; - to validate equipment and processes and confirm operational performances of the system during prior tests in 'non-active' or 'slightly active' conditions before the operational phase; - to be actively involved in site operations, in order to trouble-shout, fine-tune and constantly improve equipment and processes, using their own operators, technicians and engineers in order to guarantee the availability of the system in all circumstances; - to establish with the prime contractor, or other participating companies 'partnering' or 'alliance' agreements during operational phases, in order to motivate all actors

  19. Knowledge representation for integrated plant operation and maintenance

    DEFF Research Database (Denmark)

    Lind, Morten

    2010-01-01

    Integrated operation and maintenance of process plants has many advantages. One advantage is the improved economy obtained by reducing the number of plant shutdowns. Another is to increase reliability of operation by monitoring of risk levels during on-line maintenance. Integrated plant operation...... and maintenance require knowledge bases which can capture the interactions between the two plant activities. As an example, taking out a component or a subsystem for maintenance during operation will require a knowledge base representing the interactions between plant structure, functions, operating states...... and goals and incorporate knowledge about redundancy and reliability data. Multilevel Flow Modeling can be used build knowledge bases representing plant goals and functions and has been applied for fault diagnosis and supervisory control but currently it does not take into account structural information...

  20. Operator role definition and human-system integration

    International Nuclear Information System (INIS)

    Knee, H.E.; Schryver, J.C.

    1989-01-01

    This paper discusses operator role definition and human-system integration from a perspective of systems engineering and allocation of functions. Current and traditional allocation of tasks/functions can no longer by applied to systems that are significantly more sophisticated and dynamic than current system designs. For such advanced and automated designs, explicit attention must be given to the role of the operator in order to facilitate efficient system performance. Furthermore, such systems will include intelligent automated systems which will support the cognitive activities of the operator. If such systems share responsibility and control with the human operator, these computer-based assistants/associates should be viewed as intelligent team members. As such, factors such as trust, intentions, and expectancies, among team members must be considered by the systems designer. Such design considerations are discussed in this paper. This paper also discusses the area of dynamic allocation of functions, and the need for models of the human operator in support of machine forecast of human performance. The Integrated Reactor Operator/System (INTEROPS) model is discussed as an example of a cognitive model capable of functioning beyond a rule-based behavioral structure

  1. Ground Operations Autonomous Control and Integrated Health Management

    Science.gov (United States)

    Daniels, James

    2014-01-01

    The Ground Operations Autonomous Control and Integrated Health Management plays a key role for future ground operations at NASA. The software that is integrated into this system is called G2 2011 Gensym. The purpose of this report is to describe the Ground Operations Autonomous Control and Integrated Health Management with the use of the G2 Gensym software and the G2 NASA toolkit for Integrated System Health Management (ISHM) which is a Computer Software Configuration Item (CSCI). The decision rationale for the use of the G2 platform is to develop a modular capability for ISHM and AC. Toolkit modules include knowledge bases that are generic and can be applied in any application domain module. That way, there's a maximization of reusability, maintainability, and systematic evolution, portability, and scalability. Engine modules are generic, while application modules represent the domain model of a specific application. Furthermore, the NASA toolkit, developed since 2006 (a set of modules), makes it possible to create application domain models quickly, using pre-defined objects that include sensors and components libraries for typical fluid, electrical, and mechanical systems.

  2. Integrated test plan ResonantSonic drilling system technology demonstration-1995, at the Hanford Site: Revision 1

    International Nuclear Information System (INIS)

    McLellan, G.W.

    1994-01-01

    This integrated test plan describes the demonstration test of the ResonantSonic drilling system. This demonstration is part of the Office of Technology Development's Volatile Organic Compound Arid Integrated Demonstration (VOC-Arid ID). Two main purposes of this demonstration are (1) to continue testing the ResonantSonic drilling system compatibility with the Hanford Site waste characterization programs, and (2) to transfer this method for use at the Hanford Site, other government sites, and the private sector. The ResonantSonic method is a dry drilling technique. Field testing of this method began in July 1993. During the next four months, nine holes were drilled, and continuous core samples were retrieved. Penetration rates were 2 to 3 times the baseline, and the operational downtime rate was less than 10%. Successfully demonstrated equipment refinements included a prototype 300 series ResonantSonic head, a new drill rod design for 18-centimeter diameter pipe, and an automated pipe handling system. Various configurations of sampling equipment and drill bits were tested, depending on geologic conditions. The principal objective of the VOC-Arid ID is to determine the viability of emerging technologies that can be used to characterize, remediate, and/or monitor arid or semiarid sites containing VOCs (e.g., carbon tetrachloride) with or without associated metal and radionuclide contamination

  3. The safeguards on-site laboratory at Sellafield. Five years operational experience

    Energy Technology Data Exchange (ETDEWEB)

    Duinslaeger, L.; Belle, P. van; Mayer, K.; Casteleyn, K.; Abousahl, S.; Daures, P.; Eberle, H.; Enright, T.; Guiot, A.; Hild, M.; Horta Domenech, J.; Lajarge, P.; Laurent, P.; Le Terrier, A.; Lynch, B.; Marucci, M.; Millet, S.; Ottmar, H.; Richir, P.; Street, S.; Vallet, P.; Zuleger, E. [European Commission, Karlsruhe (Germany). Inst. for Transuranium Elements

    2004-06-01

    The start of operation of the large reprocessing facilities led Euratom Safeguards to a new approach for verification analysis of samples taken at the facility: the installation of on-site laboratories. The availability of analytical capabilities for independent verification measurements at the site of these facilities offers obvious advantages in view of timeliness of results. The 'On-Site Laboratory' (OSL) at the BNFL Sellafield site was the first ever and entered into operation in 1999. For almost five years, the Institute for Transuranium Elements (ITU) has been operating the laboratory under routine conditions. During this period, more than one thousand safeguards samples were analysed. The experience gained in the management, logistics and operation of the OSL allow a critical review based on a significant period in time. This includes also aspects of training of staff, maintenance of equipment, flow of information, and improvements in the efficiency. The analytical issues are of key importance: based on the operational experience, the measurement methods were adapted (changing boundary conditions), the distribution of samples according to material type changed (start up of MOS fabrication plant), and the cutback in resources triggered a further streamlining of the analytical efforts. (orig.)

  4. Some classes of analytic functions involving Noor integral operator

    Science.gov (United States)

    Patel, J.; Cho, N. E.

    2005-12-01

    The object of the present paper is to investigate some inclusion properties of certain subclasses of analytic functions defined by using the Noor integral operator. The integral preserving properties in connection with the operator are also considered. Relevant connections of the results presented here with those obtained in earlier works are pointed out.

  5. Environmental analysis of the operation of Oak Ridge National Laboratory (X-10 site)

    Energy Technology Data Exchange (ETDEWEB)

    Boyle, J.W.; Blumberg, R.; Cotter, S.J.

    1982-11-01

    An environmental analysis of the operation of the Oak Ridge National Laboratory (ORNL) facilities in Bethel Valley and Melton Valley was conducted to present to the public information concerning the extent to which recognizable effects, or potential effects, on the environment may occur. The analysis addresses current operations of the ORNL X-10 site and completed operations that may continue to have residual effects. Solid wastes from ORNL operations at the Y-12 site which are transported to the X-10 site for burial (e.g., Biology Division animal wastes) are included as part of X-10 site operation. Socioeconomic effects are associated primarily with the communities where employees live and with the Knoxville Bureau of Economic Analysis economic area as a whole. Therefore, ORNL employees at both Y-12 and X-10 sites are included in the ORNL socioeconomic impact analysis. An extensive base of environmental data was accumulated for this report. Over 80 reports related to ORNL facilities and/or operations are cited as well as many open-literature citations. Environmental effects of the operation of ORNL result from operational discharges from the onsite facilities; construction and/or modification of facilities, transportation to and from the site of persons, goods and services; socioeconomic impacts to the local, regional, and general population; and accidental discharges if they should occur. Operational discharges to the environnment are constrained by federal, state, and local regulations and by criteria established by the US Department of Energy to minimize adverse impacts. It is the purpose of this document to evaluate the operation of the ORNL insofar as impacts beyond the site boundary may occur or have the potential for occurrence.

  6. Environmental analysis of the operation of Oak Ridge National Laboratory (X-10 site)

    International Nuclear Information System (INIS)

    Boyle, J.W.; Blumberg, R.; Cotter, S.J.

    1982-11-01

    An environmental analysis of the operation of the Oak Ridge National Laboratory (ORNL) facilities in Bethel Valley and Melton Valley was conducted to present to the public information concerning the extent to which recognizable effects, or potential effects, on the environment may occur. The analysis addresses current operations of the ORNL X-10 site and completed operations that may continue to have residual effects. Solid wastes from ORNL operations at the Y-12 site which are transported to the X-10 site for burial (e.g., Biology Division animal wastes) are included as part of X-10 site operation. Socioeconomic effects are associated primarily with the communities where employees live and with the Knoxville Bureau of Economic Analysis economic area as a whole. Therefore, ORNL employees at both Y-12 and X-10 sites are included in the ORNL socioeconomic impact analysis. An extensive base of environmental data was accumulated for this report. Over 80 reports related to ORNL facilities and/or operations are cited as well as many open-literature citations. Environmental effects of the operation of ORNL result from operational discharges from the onsite facilities; construction and/or modification of facilities, transportation to and from the site of persons, goods and services; socioeconomic impacts to the local, regional, and general population; and accidental discharges if they should occur. Operational discharges to the environnment are constrained by federal, state, and local regulations and by criteria established by the US Department of Energy to minimize adverse impacts. It is the purpose of this document to evaluate the operation of the ORNL insofar as impacts beyond the site boundary may occur or have the potential for occurrence

  7. Integrating Sustainable Development into Operations Management Courses

    Science.gov (United States)

    Fredriksson, Peter; Persson, Magnus

    2011-01-01

    Purpose: It is widely acknowledged that aspects of sustainable development (SD) should be integrated into higher level operations management (OM) education. The aim of the paper is to outline the experiences gained at Chalmers University of Technology in Sweden from integrating aspects of SD into OM courses. Design/methodology/approach: The paper…

  8. NN-SITE: A remote monitoring testbed facility

    International Nuclear Information System (INIS)

    Kadner, S.; White, R.; Roman, W.; Sheely, K.; Puckett, J.; Ystesund, K.

    1997-01-01

    DOE, Aquila Technologies, LANL and SNL recently launched collaborative efforts to create a Non-Proliferation Network Systems Integration and Test (NN-Site, pronounced N-Site) facility. NN-Site will focus on wide area, local area, and local operating level network connectivity including Internet access. This facility will provide thorough and cost-effective integration, testing and development of information connectivity among diverse operating systems and network topologies prior to full-scale deployment. In concentrating on instrument interconnectivity, tamper indication, and data collection and review, NN-Site will facilitate efforts of equipment providers and system integrators in deploying systems that will meet nuclear non-proliferation and safeguards objectives. The following will discuss the objectives of ongoing remote monitoring efforts, as well as the prevalent policy concerns. An in-depth discussion of the Non-Proliferation Network Systems Integration and Test facility (NN-Site) will illuminate the role that this testbed facility can perform in meeting the objectives of remote monitoring efforts, and its potential contribution in promoting eventual acceptance of remote monitoring systems in facilities worldwide

  9. VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites.

    Science.gov (United States)

    Spinozzi, Giulio; Calabria, Andrea; Brasca, Stefano; Beretta, Stefano; Merelli, Ivan; Milanesi, Luciano; Montini, Eugenio

    2017-11-25

    Bioinformatics tools designed to identify lentiviral or retroviral vector insertion sites in the genome of host cells are used to address the safety and long-term efficacy of hematopoietic stem cell gene therapy applications and to study the clonal dynamics of hematopoietic reconstitution. The increasing number of gene therapy clinical trials combined with the increasing amount of Next Generation Sequencing data, aimed at identifying integration sites, require both highly accurate and efficient computational software able to correctly process "big data" in a reasonable computational time. Here we present VISPA2 (Vector Integration Site Parallel Analysis, version 2), the latest optimized computational pipeline for integration site identification and analysis with the following features: (1) the sequence analysis for the integration site processing is fully compliant with paired-end reads and includes a sequence quality filter before and after the alignment on the target genome; (2) an heuristic algorithm to reduce false positive integration sites at nucleotide level to reduce the impact of Polymerase Chain Reaction or trimming/alignment artifacts; (3) a classification and annotation module for integration sites; (4) a user friendly web interface as researcher front-end to perform integration site analyses without computational skills; (5) the time speedup of all steps through parallelization (Hadoop free). We tested VISPA2 performances using simulated and real datasets of lentiviral vector integration sites, previously obtained from patients enrolled in a hematopoietic stem cell gene therapy clinical trial and compared the results with other preexisting tools for integration site analysis. On the computational side, VISPA2 showed a > 6-fold speedup and improved precision and recall metrics (1 and 0.97 respectively) compared to previously developed computational pipelines. These performances indicate that VISPA2 is a fast, reliable and user-friendly tool for

  10. DNFSB Recommendation 94-1 Hanford Site Integrated Stabilization Management Plan. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Gerber, E.W.

    1995-10-01

    The US Department of Energy (DOE) has developed an Integrated Program Plan (IPP) to address concerns identified in Defense Nuclear Facilities Safety Board Recommendation 94-1. The IPP describes the actions that DOE plans to implement at its various sites to convert excess fissile materials to forms or conditions suitable for safe interim storage. The baseline IPP was issued as DOE`s Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1 Implementation Plan (IP), which was transmitted to the DNFSB on February 28, 1995. The IPP is being further developed to include complex-wide requirements for research and development and a long-range facility requirements section. The planned additions to the baseline IPP are being developed based on a systems engineering approach that integrates facilities and capabilities at the various DOE sites and focuses on attaining safe interim storage with minimum safety risks and environmental impacts. Each affected DOE site has developed a Site Integrated Stabilization Management Plan (SISMP) to identify individual site plans to implement the DNFSB Recommendation 94-1 and to provide a basis for formulating planned additions to the IPP. The SISMPs were developed based on the objectives, requirements, and commitments identified in the baseline DNFSB Recommendation 94-1 IPP. The SISMPs will be periodically updated to reflect improved integration between DOE sites as identified during the IPP systems engineering evaluations.

  11. DNFSB Recommendation 94-1 Hanford Site Integrated Stabilization Management Plan. Volume 1

    International Nuclear Information System (INIS)

    Gerber, E.W.

    1995-10-01

    The US Department of Energy (DOE) has developed an Integrated Program Plan (IPP) to address concerns identified in Defense Nuclear Facilities Safety Board Recommendation 94-1. The IPP describes the actions that DOE plans to implement at its various sites to convert excess fissile materials to forms or conditions suitable for safe interim storage. The baseline IPP was issued as DOE's Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1 Implementation Plan (IP), which was transmitted to the DNFSB on February 28, 1995. The IPP is being further developed to include complex-wide requirements for research and development and a long-range facility requirements section. The planned additions to the baseline IPP are being developed based on a systems engineering approach that integrates facilities and capabilities at the various DOE sites and focuses on attaining safe interim storage with minimum safety risks and environmental impacts. Each affected DOE site has developed a Site Integrated Stabilization Management Plan (SISMP) to identify individual site plans to implement the DNFSB Recommendation 94-1 and to provide a basis for formulating planned additions to the IPP. The SISMPs were developed based on the objectives, requirements, and commitments identified in the baseline DNFSB Recommendation 94-1 IPP. The SISMPs will be periodically updated to reflect improved integration between DOE sites as identified during the IPP systems engineering evaluations

  12. Research on Integration of NPP Operational Safety Management Performance Systems

    International Nuclear Information System (INIS)

    Chi, Miao; Shi, Liping

    2014-01-01

    The operational safety management of Nuclear Power Plants demands systematic planning and integrated control. NPPs are following the well-developed safety indicator systems proposed by IAEA Operational Safety Performance Indicator Programme, NRC Reactor Oversight Process or the other institutions. Integration of the systems is proposed to benefiting from the advantages of both systems and avoiding improper application into the real world. The authors analyzed the possibility and necessity for system integration, and propose an indicator system integrating method

  13. Development and trial operation of a site-wide computerized material accounting system at Kurchatov Institute

    International Nuclear Information System (INIS)

    Roumiantsev, A.N.; Ostroumov, Y.A.; Yevstropov, A.V.

    1997-01-01

    Since August 1994 Kurchatov Institute in cooperation with several US Department of Energy Laboratories has been developing a site-wide computerized material accounting system for nuclear materials. In 1994 a prototype system was put into trial operation at two Kurchatov facilities. Evaluation of this prototype led to the development of a new computerized material accounting system named KI-MACS, which has been operational since 1996. This system is a site-wide local secure computer network with centralized database capable of dealing with strictly confidential data and performing near-real time accountancy. It utilizes a Microsoft Windows NT operating system with SQL Server and Visual Basic, and has a 'star'-like network architecture. KI-MACS is capable of dealing with materials in itemized and bulk form, and can perform statistical evaluations of measurements and material balance. KI-MACS is fully integrated with bar code equipment, electronic scales, gamma-ray spectrometers and an Active Well Coincidence Counter, thus providing almost on-line evaluation and utilization of results of measurements, item identification and accounting. At present KI-MACS is being used in Physical Inventory Taking at the Kurchatov Central Storage Facility, and by the end of 1997 will be installed at twelve Kurchatov nuclear facilities

  14. Development and trial operation of a site-wide computerized material accounting system at Kurchatov Institute

    Energy Technology Data Exchange (ETDEWEB)

    Roumiantsev, A.N.; Ostroumov, Y.A.; Yevstropov, A.V. [Kurchatov Institute RRC, Moscow (Russian Federation)] [and others

    1997-11-01

    Since August 1994 Kurchatov Institute in cooperation with several US Department of Energy Laboratories has been developing a site-wide computerized material accounting system for nuclear materials. In 1994 a prototype system was put into trial operation at two Kurchatov facilities. Evaluation of this prototype led to the development of a new computerized material accounting system named KI-MACS, which has been operational since 1996. This system is a site-wide local secure computer network with centralized database capable of dealing with strictly confidential data and performing near-real time accountancy. It utilizes a Microsoft Windows NT operating system with SQL Server and Visual Basic, and has a `star`-like network architecture. KI-MACS is capable of dealing with materials in itemized and bulk form, and can perform statistical evaluations of measurements and material balance. KI-MACS is fully integrated with bar code equipment, electronic scales, gamma-ray spectrometers and an Active Well Coincidence Counter, thus providing almost on-line evaluation and utilization of results of measurements, item identification and accounting. At present KI-MACS is being used in Physical Inventory Taking at the Kurchatov Central Storage Facility, and by the end of 1997 will be installed at twelve Kurchatov nuclear facilities.

  15. Essay on Fractional Riemann-Liouville Integral Operator versus Mikusinski’s

    Directory of Open Access Journals (Sweden)

    Ming Li

    2013-01-01

    Full Text Available This paper presents the representation of the fractional Riemann-Liouville integral by using the Mikusinski operators. The Mikusinski operators discussed in the paper may yet provide a new view to describe and study the fractional Riemann-Liouville integral operator. The present result may be useful for applying the Mikusinski operational calculus to the study of fractional calculus in mathematics and to the theory of filters of fractional order in engineering.

  16. Eigenvalue estimates of positive integral operators with analytic ...

    Indian Academy of Sciences (India)

    Eigenvalue estimates of positive integral operators. 337 will be used to denote, respectively, the complex line integral of f along γ and the integral of f with respect to arc-length measure. In the first case we assume γ has an orientation. The notation Lp(γ ) will denote the Lp space of normalized arc length measure on γ with.

  17. Development of operation control expert system for off-site facilities

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, Masaaki

    1988-09-01

    Concerning off-site facilities of oil refinary, changes of facilities and equipment are frequently made in order to cope flexibly with the market trends and changes of the social environment. In addition, it is desirable to introduce computerization into control and manipulation of off-site facilities for its fast, safe and sure operation. In order to achieve the above, against the existing exclusively control-oriented system, it is necessary to add the processing and generating functions to combinations between valves to be shut and piping as well as equipment to be used along the whole extent of the oil flow in the system and to add the function which makes verification of the above functions easy through a dialogue between users and the system. In order to realize the above, Cosmo Oil and Yokokawa Denki developed jointly an operation control expert system for off-site facilities and the system started its actual operation from October 1986. This article is an outline of the system. The result of its actual operation for one and a half years since its inception showed that the system was operated only by the staff responsible for the operation of the facilities, the workload was reduced to 1/3-1/4 of the workload before the adoption of the system and absolutely no omission of work nor mistake was experienced. (2 figs)

  18. Analysis of Optimal Operation of an Energy Integrated Distillation Plant

    DEFF Research Database (Denmark)

    Li, Hong Wen; Hansen, C.A.; Gani, Rafiqul

    2003-01-01

    The efficiency of manufacturing systems can be significantly increased through diligent application of control based on mathematical models thereby enabling more tight integration of decision making with systems operation. In the present paper analysis of optimal operation of an energy integrated...

  19. Quality assurance in Hanford site defense waste operations

    International Nuclear Information System (INIS)

    Wojtasek, R.D.

    1989-01-01

    This paper discusses quality assurance as an integral part of conducting waste management operations. The storage, treatment, and disposal of radioactive and non- radioactive hazardous wastes at Hanford are described. The author reports that quality assurance programs provide confidence that storage, treatment, and disposal facilities and systems perform as intended. Examples of how quality assurance is applied to Hanford defense waste operations are presented

  20. Spherical and plane integral operators for PDEs construction, analysis, and applications

    CERN Document Server

    Sabelfeld, Karl K

    2013-01-01

    The book presents integral formulations for partial differential equations, with the focus on spherical and plane integral operators. The integral relations are obtained for different elliptic and parabolic equations, and both direct and inverse mean value relations are studied. The derived integral equations are used to construct new numerical methods for solving relevant boundary value problems, both deterministic and stochastic based on probabilistic interpretation of the spherical and plane integral operators.

  1. Development of transportation operations requirements

    International Nuclear Information System (INIS)

    Grady, S.T.; Best, R.E.; Danese, F.L.; Peterson, R.W.; Pope, R.B.

    1990-01-01

    Transport conditions at various utility sties vary dramatically in terms of characteristics at and near the site, requirements, administrative procedures, and other factors. Continuation of design efforts for the OCRWM transportation operations system requires that the operating requirements for the transportation system -- quantity of fuel per unit time per site -- be identified so that the effect the variations have on the system can be accommodated. The approach outlined in this paper provides for an identification of specific sites, evaluation of shipment capabilities at each site, and integration of the sites into multi-site shipping campaigns to scope the logistics management problem for the transportation operations system. 1 fig., 1 tab

  2. Site operator program final report for fiscal years 1992 through 1996

    Energy Technology Data Exchange (ETDEWEB)

    Francfort, J.E. [Lockheed Martin Idaho Technologies Co., Idaho Falls, ID (United States). Idaho National Engineering and Environmental Lab.; Bassett, R.R. [Sandia National Labs., Albuquerque, NM (United States); Birasco, S. [Los Angeles Dept. of Water and Power, CA (United States)] [and others

    1998-01-01

    The Site Operator Program was an electric vehicle testing and evaluation program sponsored by US Department of Energy and managed at the Idaho National Engineering and Environmental Laboratory. The Program`s goals included the field evaluation of electric vehicles in real-world applications and environments; the support of electric vehicle technology advancement; the development of infrastructure elements necessary to support significant electric vehicle use; and increasing the awareness and acceptance of electric vehicles. This report covers Program activities from 1992 to 1996. The Site Operator Program ended in September 1996, when it was superseded by the Field Operations Program. Electric vehicle testing included baseline performance testing, which was performed in conjunction with EV America. The baseline performance parameters included acceleration, braking, range, energy efficiency, and charging time. The Program collected fleet operations data on electric vehicles operated by the Program`s thirteen partners, comprising electric utilities, universities, and federal agencies. The Program`s partners had over 250 electric vehicles, from vehicle converters and original equipment manufacturers, in their operating fleets. Test results are available via the World Wide Web site at http://ev.inel.gov/sop.

  3. Defense waste management operations at the Nevada Test Site

    International Nuclear Information System (INIS)

    Williams, R.E.; Kendall, E.W.

    1988-01-01

    Waste management activities were initiated at the Nevada Test Site (NTS) to dispose of low-level wastes (LLW) produced by the Department of Energy's (DOE's) weapons testing program. Disposal activities have expanded from the burial of atmospheric weapons testing debris to demonstration facilities for greater-than-Class-C (GTCC) waste, transuranic (TRU) waste storage and certification, and the development of a mixed waste (MW) facility. Site specific operational research projects support technology development required for the various disposal facilities. The annual cost of managing the facilities is about $6 million depending on waste volumes and types. The paper discusses site selection; establishment of the Radioactive Waste Management Project; operations with respect to low-level radioactive wastes, transuranic waste storage, greater confinement disposal test, and mixed waste management facility; and related research activities such as tritium migration studies, revegetation studies, and in-situ monitoring of organics

  4. The Decoration Operator: A Foundation for On-Line Dimensional Data Integration

    DEFF Research Database (Denmark)

    Pedersen, Dennis; Pedersen, Torben Bach; Riis, Karsten

    2004-01-01

    The changing data requirements of today's dynamic business environments are not handled well by current On-Line Analytical Processing (OLAP) systems. Physically integrating unexpected, external data into OLAP cubes, i.e., the data warehousing approach, is a long and time-consuming process, making...... logical, on-the-fly, integration the better choice in many situations. However, OLAP systems have no operations for integrating existing multidimensional cube data with external data. In this paper we present a novel multidimensional algebra operator, the decoration operator, which allows external data...... to be integrated in OLAP cubes as new dimensions, i.e., the cube is ``decorated'' with new dimensions which can subsequently be used just as the regular dimensions. We formally specify the semantics of the decoration operator, ensuring that semantic problems do not occur in the data integration process. We also...

  5. Integral type operators from normal weighted Bloch spaces to QT,S spaces

    Directory of Open Access Journals (Sweden)

    Yongyi GU

    2016-08-01

    Full Text Available Operator theory is an important research content of the analytic function space theory. The discussion of simultaneous operator and function space is an effective way to study operator and function space. Assuming that  is an analytic self map on the unit disk Δ, and the normal weighted bloch space μ-B is a Banach space on the unit disk Δ, defining a composition operator C∶C(f=f on μ-B for all f∈μ-B, integral type operator JhC and CJh are generalized by integral operator and composition operator. The boundeness and compactness of the integral type operator JhC acting from normal weighted Bloch spaces to QT,S spaces are discussed, as well as the boundeness of the integral type operators CJh acting from normal weighted Bloch spaces to QT,S spaces. The related sufficient and necessary conditions are given.

  6. Hanford Site waste treatment/storage/disposal integration

    International Nuclear Information System (INIS)

    MCDONALD, K.M.

    1999-01-01

    In 1998 Waste Management Federal Services of Hanford, Inc. began the integration of all low-level waste, mixed waste, and TRU waste-generating activities across the Hanford site. With seven contractors, dozens of generating units, and hundreds of waste streams, integration was necessary to provide acute waste forecasting and planning for future treatment activities. This integration effort provides disposition maps that account for waste from generation, through processing, treatment and final waste disposal. The integration effort covers generating facilities from the present through the life-cycle, including transition and deactivation. The effort is patterned after the very successful DOE Complex EM Integration effort. Although still in the preliminary stages, the comprehensive onsite integration effort has already reaped benefits. These include identifying significant waste streams that had not been forecast, identifying opportunities for consolidating activities and services to accelerate schedule or save money; and identifying waste streams which currently have no path forward in the planning baseline. Consolidation/integration of planned activities may also provide opportunities for pollution prevention and/or avoidance of secondary waste generation. A workshop was held to review the waste disposition maps, and to identify opportunities with potential cost or schedule savings. Another workshop may be held to follow up on some of the long-term integration opportunities. A change to the Hanford waste forecast data call would help to align the Solid Waste Forecast with the new disposition maps

  7. An integrated study of spatial multicriteria analysis and mathematical modelling for managed aquifer recharge site suitability mapping and site ranking at Northern Gaza coastal aquifer.

    Science.gov (United States)

    Rahman, Mohammad Azizur; Rusteberg, Bernd; Uddin, Mohammad Salah; Lutz, Annegret; Saada, Muath Abu; Sauter, Martin

    2013-07-30

    This paper describes an integrated approach of site suitability mapping and ranking of the most suitable sites, for the implementation of Managed Aquifer Recharge (MAR) projects, using spatial multicriteria decision analysis (SMCDA) techniques and mathematical modelling. The SMCDA procedure contains constraint mapping, site suitability analysis with criteria standardization and weighting, criteria overlay by analytical hierarchy process (AHP) combined with weighted linear combination (WLC) and ordered weighted averaging (OWA), and sensitivity analysis. The hydrogeological impacts of the selected most suitable sites were quantified by using groundwater flow and transport modelling techniques. Finally, ranking of the selected sites was done with the WLC method. The integrated approach is demonstrated by a case study in the coastal aquifer of North Gaza. Constraint mapping shows that 50% of the total study area is suitable for MAR implementation. About 25% of the total area is "very good" and 25% percent is "good" for MAR, according to the site suitability analysis. Six locations were selected and ranked against six representative decision criteria. Long term (year 2003 to year 2040) groundwater flow and transport simulations were performed to quantify the selected criteria under MAR project operation conditions at the selected sites. Finally, the suitability mapping and hydrogeological investigation recommends that the location of the existing infiltration ponds, constructed near the planned North Gaza Wastewater Treatment Plant (NGWWTP) is most suitable for MAR project implementation. This paper concludes that mathematical modelling should be combined with the SMCDA technique in order to select the best location for MAR project implementation. Besides MAR project implementation, the generalised approach can be applicable for any other water resources development project that deals with site selection and implementation. Copyright © 2013 Elsevier Ltd. All rights

  8. Taking interim actions: Integrating CERCLA and NEPA to move ahead with site cleanup

    International Nuclear Information System (INIS)

    MacDonell, M.M.; Peterson, J.M.; Valett, G.L.; McCracken, S.H.

    1991-01-01

    The cleanup of contaminated sites can be expedited by using interim response actions in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, and the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). In fact, a major portion of some Superfund sites can be cleaned up using interim actions. For CERCLA sites being remediated by the US Department of Energy (DOE), such actions must also comply with the National Environmental Policy Act (NEPA) because the DOE has established a policy for integrating CERCLA and NEPA requirements. A strategy for the integrated documentation with implementation of interim actions has been applied successfully at the Weldon Spring site, and major cleanup projects are currently underway. This paper discusses some of the issues associated with integrating CERCLA and NEPA for interim actions and summarizes those actions that have been identified for the Weldon Spring site

  9. Taking interim actions: Integrating CERCLA and NEPA to move ahead with site cleanup

    International Nuclear Information System (INIS)

    MacDonell, M.M.; Peterson, J.M.; Valett, G.L.; McCracken, S.H.

    1991-01-01

    The cleanup of contaminated sites can be expedited by using interim response actions in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, and the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). In fact, a major portion of some Superfund sites can be cleaned up using interim actions. For CERCLA sites being remediated by the US Department of Energy (DOE), such actions must also comply with the National Environmental Policy Act (NEPA) because the DOE has established a policy for integrating CERCLA and NEPA requirements. A strategy for the integrated documentation and implementation of interim actions has been applied successfully at the Weldon Spring site, and major cleanup projects are currently underway. This paper discusses some of the issues associated with integrating CERCLA and NEPA for interim actions and summarizes those actions that have been identified for the Weldon Spring site

  10. A DOE multi-site approach to safeguards integration with facility operations

    International Nuclear Information System (INIS)

    Ostenak, C.A.

    1987-01-01

    The Accountability Technology Exchange (ATEX) Working Group was established in October 1986 by the US Department of Energy (DOE) to help identify nuclear materials accountability measurement needs within the DOE plutonium community and recommend potential improvements. ATEX Working Group membership represents nuclear materials production, safeguards, nondestructive assay (NDA), and analytical chemistry at a multitude of DOE plutonium sites. Currently, the ATEX Working Group has identified twenty NDA accountability measurement needs that fall into five major classes: NDA standards representing various nuclear materials and matrix compositions; NDA for impure nuclear materials compounds, residues, and wastes; NDA for product-grade nuclear materials; NDA for nuclear materials process holdup and in-process inventory; and NDA for nuclear materials item control and verification. Specific needs within these classes have been evaluated and ranked for individual sites and for the total DOE plutonium community

  11. Operating procedures for the Pajarito Site Critical Assembly Facility

    International Nuclear Information System (INIS)

    Malenfant, R.E.

    1983-03-01

    Operating procedures consistent with DOE Order 5480.2, Chapter VI, and the American National Standard Safety Guide for the Performance of Critical Experiments are defined for the Pajarito Site Critical Assembly Facility of the Los Alamos National Laboratory. These operating procedures supersede and update those previously published in 1973 and apply to any criticality experiment performed at the facility

  12. Study on the operational guides of the off-site emergency management center

    International Nuclear Information System (INIS)

    Park, Won Jong; Han, S. J.; Oh, K. H.

    2005-01-01

    The emergency response organizational groups and roles of Off-site Emergency Management Center was proposed to respond in case of radiological emergency. Development of implementing procedures of Off-site Emergency Management Center in case of radiological emergency to improve effective co-operation and rapid response in radiological emergency. Establishment of 'The Ordinance of Operation of residence radiological emergency office of the Minister of Science and Technology' and announced by the Minister of Science and Technology. The Implementing procedures of Off-site Emergency Management Center and 'The Ordinance of Operation of residence radiological emergency office of the Minister of Science and Technology' can be provide guidelines in case of emergency

  13. Achieving High Reliability Operations Through Multi-Program Integration

    Energy Technology Data Exchange (ETDEWEB)

    Holly M. Ashley; Ronald K. Farris; Robert E. Richards

    2009-04-01

    Over the last 20 years the Idaho National Laboratory (INL) has adopted a number of operations and safety-related programs which has each periodically taken its turn in the limelight. As new programs have come along there has been natural competition for resources, focus and commitment. In the last few years, the INL has made real progress in integrating all these programs and are starting to realize important synergies. Contributing to this integration are both collaborative individuals and an emerging shared vision and goal of the INL fully maturing in its high reliability operations. This goal is so powerful because the concept of high reliability operations (and the resulting organizations) is a masterful amalgam and orchestrator of the best of all the participating programs (i.e. conduct of operations, behavior based safety, human performance, voluntary protection, quality assurance, and integrated safety management). This paper is a brief recounting of the lessons learned, thus far, at the INL in bringing previously competing programs into harmony under the goal (umbrella) of seeking to perform regularly as a high reliability organization. In addition to a brief diagram-illustrated historical review, the authors will share the INL’s primary successes (things already effectively stopped or started) and the gaps yet to be bridged.

  14. Geographic and Operational Site Parameters List (GOSPL) for Hanford Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Last, George V.; Nichols, William E.; Kincaid, Charles T.

    2006-06-01

    This data package was originally prepared to support a 2004 composite analysis (CA) of low-level waste disposal at the Hanford Site. The Technical Scope and Approach for the 2004 Composite Analysis of Low Level Waste Disposal at the Hanford Site (Kincaid et. al. 2004) identified the requirements for that analysis and served as the basis for initial preparation of this data package. Completion of the 2004 CA was later deferred, with the 2004 Annual Status Report for the Composite Analysis of Low-Level Waste Disposal in the Central Plateau at the Hanford Site (DOE 2005) indicating that a comprehensive update to the CA was in preparation and would be submitted in 2006. However, the U.S. Department of Energy (DOE) has recently decided to further defer the CA update and will use the cumulative assessment currently under preparation for the environmental impact statement (EIS) being prepared for tank closure and other site decisions as the updated CA. Submittal of the draft EIS is currently planned for FY 2008. This data package describes the facility-specific parameters (e.g. location, operational dates, etc.) used to numerically simulate contaminant flow and transport in large-scale Hanford assessments. Kincaid et al. (2004) indicated that the System Assessment Capability (SAC) (Kincaid et al. 2000; Bryce et al. 2002; Eslinger 2002a, 2002b) would be used to analyze over a thousand different waste sites. A master spreadsheet termed the Geographic and Operational Site Parameters List (GOSPL) was assembled to facilitate the generation of keyword input files containing general information on each waste site/facility, its operational/disposal history, and its environmental settings (past, current, and future). This report briefly describes each of the key data fields, including the source(s) of data, and provides the resulting inputs to be used for large-scale Hanford assessments.

  15. Lentivector Integration Sites in Ependymal Cells From a Model of Metachromatic Leukodystrophy: Non-B DNA as a New Factor Influencing Integration

    Science.gov (United States)

    McAllister, Robert G; Liu, Jiahui; Woods, Matthew W; Tom, Sean K; Rupar, C Anthony; Barr, Stephen D

    2014-01-01

    The blood–brain barrier controls the passage of molecules from the blood into the central nervous system (CNS) and is a major challenge for treatment of neurological diseases. Metachromatic leukodystrophy is a neurodegenerative lysosomal storage disease caused by loss of arylsulfatase A (ARSA) activity. Gene therapy via intraventricular injection of a lentiviral vector is a potential approach to rapidly and permanently deliver therapeutic levels of ARSA to the CNS. We present the distribution of integration sites of a lentiviral vector encoding human ARSA (LV-ARSA) in murine brain choroid plexus and ependymal cells, administered via a single intracranial injection into the CNS. LV-ARSA did not exhibit a strong preference for integration in or near actively transcribed genes, but exhibited a strong preference for integration in or near satellite DNA. We identified several genomic hotspots for LV-ARSA integration and identified a consensus target site sequence characterized by two G-quadruplex-forming motifs flanking the integration site. In addition, our analysis identified several other non-B DNA motifs as new factors that potentially influence lentivirus integration, including human immunodeficiency virus type-1 in human cells. Together, our data demonstrate a clinically favorable integration site profile in the murine brain and identify non-B DNA as a potential new host factor that influences lentiviral integration in murine and human cells. PMID:25158091

  16. Prolonged Integration Site Selection of a Lentiviral Vector in the Genome of Human Keratinocytes.

    Science.gov (United States)

    Qian, Wei; Wang, Yong; Li, Rui-Fu; Zhou, Xin; Liu, Jing; Peng, Dai-Zhi

    2017-03-03

    BACKGROUND Lentiviral vectors have been successfully used for human skin cell gene transfer studies. Defining the selection of integration sites for retroviral vectors in the host genome is crucial in risk assessment analysis of gene therapy. However, genome-wide analyses of lentiviral integration sites in human keratinocytes, especially after prolonged growth, are poorly understood. MATERIAL AND METHODS In this study, 874 unique lentiviral vector integration sites in human HaCaT keratinocytes after long-term culture were identified and analyzed with the online tool GTSG-QuickMap and SPSS software. RESULTS The data indicated that lentiviral vectors showed integration site preferences for genes and gene-rich regions. CONCLUSIONS This study will likely assist in determining the relative risks of the lentiviral vector system and in the design of a safe lentiviral vector system in the gene therapy of skin diseases.

  17. Feasibility study for remedial action for the Quarry Residuals Operable Unit at the Weldon Spring Site, Weldon Spring, Missouri

    International Nuclear Information System (INIS)

    1998-03-01

    The U.S. Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, which is located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis (Figure 1.1). Cleanup of the Weldon Spring site consists of several integrated components. The quarry residuals operable unit (QROU) is one of four operable units being evaluated. In accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, a remedial investigation/feasibility study (RI/FS) is being conducted to evaluate conditions and potential responses for the following areas and/or media that constitute the QROU: (1) the residual material (soil and sediment) remaining at the Weldon Spring quarry after removal of the bulk waste (about 11 million L [3 million gal] of uranium-contaminated ponded water was also addressed previous to bulk waste removal); (2) other media located in the surrounding vicinity of the quarry, including adjacent soil, surface water, and sediment in Femme Osage Slough and several creeks; and (3) quarry groundwater located primarily north of Femme Osage Slough. Potential impacts to the St. Charles County well field downgradient of the quarry area are also being addressed as part of QROU RI/FS evaluations. For remedial action sites, it is DOE policy to integrate values associated with the National Environmental Policy Act (NEPA) into the CERCLA decision-making process. The analyses contained herein address NEPA values as appropriate to the actions being considered for the QROU. A work plan summarizing initial site conditions and providing conceptual site hydrogeological and exposure models was published in January 1994. The RI and baseline risk assessment (BRA) reports have been completed. The RI discusses in detail the nature and extent and the fate and transport of contamination at the quarry area

  18. Feasibility study for remedial action for the Quarry Residuals Operable Unit at the Weldon Spring Site, Weldon Spring, Missouri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The U.S. Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, which is located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis (Figure 1.1). Cleanup of the Weldon Spring site consists of several integrated components. The quarry residuals operable unit (QROU) is one of four operable units being evaluated. In accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, a remedial investigation/feasibility study (RI/FS) is being conducted to evaluate conditions and potential responses for the following areas and/or media that constitute the QROU: (1) the residual material (soil and sediment) remaining at the Weldon Spring quarry after removal of the bulk waste (about 11 million L [3 million gal] of uranium-contaminated ponded water was also addressed previous to bulk waste removal); (2) other media located in the surrounding vicinity of the quarry, including adjacent soil, surface water, and sediment in Femme Osage Slough and several creeks; and (3) quarry groundwater located primarily north of Femme Osage Slough. Potential impacts to the St. Charles County well field downgradient of the quarry area are also being addressed as part of QROU RI/FS evaluations. For remedial action sites, it is DOE policy to integrate values associated with the National Environmental Policy Act (NEPA) into the CERCLA decision-making process. The analyses contained herein address NEPA values as appropriate to the actions being considered for the QROU. A work plan summarizing initial site conditions and providing conceptual site hydrogeological and exposure models was published in January 1994. The RI and baseline risk assessment (BRA) reports have been completed. The RI discusses in detail the nature and extent and the fate and transport of contamination at the quarry area.

  19. Optimizing integrated airport surface and terminal airspace operations under uncertainty

    Science.gov (United States)

    Bosson, Christabelle S.

    In airports and surrounding terminal airspaces, the integration of surface, arrival and departure scheduling and routing have the potential to improve the operations efficiency. Moreover, because both the airport surface and the terminal airspace are often altered by random perturbations, the consideration of uncertainty in flight schedules is crucial to improve the design of robust flight schedules. Previous research mainly focused on independently solving arrival scheduling problems, departure scheduling problems and surface management scheduling problems and most of the developed models are deterministic. This dissertation presents an alternate method to model the integrated operations by using a machine job-shop scheduling formulation. A multistage stochastic programming approach is chosen to formulate the problem in the presence of uncertainty and candidate solutions are obtained by solving sample average approximation problems with finite sample size. The developed mixed-integer-linear-programming algorithm-based scheduler is capable of computing optimal aircraft schedules and routings that reflect the integration of air and ground operations. The assembled methodology is applied to a Los Angeles case study. To show the benefits of integrated operations over First-Come-First-Served, a preliminary proof-of-concept is conducted for a set of fourteen aircraft evolving under deterministic conditions in a model of the Los Angeles International Airport surface and surrounding terminal areas. Using historical data, a representative 30-minute traffic schedule and aircraft mix scenario is constructed. The results of the Los Angeles application show that the integration of air and ground operations and the use of a time-based separation strategy enable both significant surface and air time savings. The solution computed by the optimization provides a more efficient routing and scheduling than the First-Come-First-Served solution. Additionally, a data driven analysis is

  20. Technology strategy for integrated operations and real time reservoir management; Technology Target Areas; TTA5 - Integrated operations and RTRM

    Energy Technology Data Exchange (ETDEWEB)

    2007-07-01

    In Norway Integrated Operations (IO) is a concept which in the first phase (G1) has been used to describe how to integrate processes and people onshore and offshore using ICT solutions and facilities that improve onshore's ability to support offshore operationally. The second generation (G2) Integrated Operations aims to help operators utilize vendors' core competencies and services more efficiently. Utilizing digital services and vendor products, operators will be able to update reservoir models, drilling targets and well trajectories as wells are drilled, manage well completions remotely, optimize production from reservoir to export lines, and implement condition-based maintenance concepts. The total impact on production, recovery rates, costs and safety will be profound. When the international petroleum business moves to the Arctic region the setting is very different from what is the case on the Norwegian Continental Shelf (NCS) and new challenges will arise. The Norwegian Ministry of Environment has recently issued an Integrated Management Plan for the Barents Sea where one focus is on 'Monitoring of the Marine Environment in the North'. The Government aims to establish a new and more coordinated system for monitoring the marine ecosystems in the north. A representative group consisting of the major Operators, the Service Industry, Academia and the Authorities have developed the enclosed strategy for the OG21 Integrated Operations and Real Time Reservoir Management (IO and RTRM) Technology Target Area (TTA). Major technology and work process research and development gaps have been identified in several areas: Bandwidth down-hole to surface; Sensor development including Nano-technology; Cross discipline use of Visualisation, Simulation and model development particularly in Drilling and Reservoir management areas; Software development in terms of data handling, model updating and calculation speed; Enabling reliable and robust communications particularly for

  1. Technology strategy for integrated operations and real time reservoir management; Technology Target Areas; TTA5 - Integrated operations and RTRM

    Energy Technology Data Exchange (ETDEWEB)

    2007-07-01

    In Norway Integrated Operations (IO) is a concept which in the first phase (G1) has been used to describe how to integrate processes and people onshore and offshore using ICT solutions and facilities that improve onshore's ability to support offshore operationally. The second generation (G2) Integrated Operations aims to help operators utilize vendors' core competencies and services more efficiently. Utilizing digital services and vendor products, operators will be able to update reservoir models, drilling targets and well trajectories as wells are drilled, manage well completions remotely, optimize production from reservoir to export lines, and implement condition-based maintenance concepts. The total impact on production, recovery rates, costs and safety will be profound. When the international petroleum business moves to the Arctic region the setting is very different from what is the case on the Norwegian Continental Shelf (NCS) and new challenges will arise. The Norwegian Ministry of Environment has recently issued an Integrated Management Plan for the Barents Sea where one focus is on 'Monitoring of the Marine Environment in the North'. The Government aims to establish a new and more coordinated system for monitoring the marine ecosystems in the north. A representative group consisting of the major Operators, the Service Industry, Academia and the Authorities have developed the enclosed strategy for the OG21 Integrated Operations and Real Time Reservoir Management (IO and RTRM) Technology Target Area (TTA). Major technology and work process research and development gaps have been identified in several areas: Bandwidth down-hole to surface; Sensor development including Nano-technology; Cross discipline use of Visualisation, Simulation and model development particularly in Drilling and Reservoir management areas; Software development in terms of data handling, model updating and calculation speed; Enabling reliable and robust communications

  2. Fractional quantum integral operator with general kernels and applications

    Science.gov (United States)

    Babakhani, Azizollah; Neamaty, Abdolali; Yadollahzadeh, Milad; Agahi, Hamzeh

    In this paper, we first introduce the concept of fractional quantum integral with general kernels, which generalizes several types of fractional integrals known from the literature. Then we give more general versions of some integral inequalities for this operator, thus generalizing some previous results obtained by many researchers.2,8,25,29,30,36

  3. Development and Application of SITES

    International Nuclear Information System (INIS)

    Park, Jo Wan; Yoon; Yoon, Jeong Hyoun; Kim, Chank Lak; Cho, Sung IL

    2008-01-01

    SITES (Site Information and Total Environmental Data Management System) has been developed for the purpose of systematically managing site characteristics and environmental data produced during the pre-operational, operational, and post-closure phases of a radioactive waste disposal facility. SITES is an integration system, which consists of 4 modules, to be available for maintenance of site characteristics data, for safety assessment, and for site/environment monitoring; site environmental data management module (SECURE), integrated safety assessment module (SAINT), site/environment monitoring module (SUDAL) and geological information module for geological data management (SITES-GIS). Each module has its database with the functions of browsing, storing, and reporting data and information. Data from SECURE and SUDAL are interconnected to be utilized as inputs to SAINT. SAINT has the functions that multi-user can access simultaneously via client-server system, and the safety assessment results can be managed with its embedded Quality Assurance feature. Comparison between assessment results and environmental monitoring data can be made and visualized in SUDAL and SITES-GIS. Also, SUDAL is designed that the periodic monitoring data and information could be opened to the public via internet homepage. SITES has applied to the Wolsong low- and intermediate-level radioactive waste disposal center in Korea, and is expected to enhance the function of site/environment monitoring in other nuclear-related facilities and also in industrial facilities handling hazardous materials.

  4. Integrating Nuclear Energy to Oilfield Operations - Two Case Studies

    International Nuclear Information System (INIS)

    Robertson, Eric P.; Nelson, Lee O.; McKellar, Michael G.; Gandrik, Anastasia M.; Patterson, Mike W.

    2011-01-01

    Fossil fuel resources that require large energy inputs for extraction, such as the Canadian oil sands and the Green River oil shale resource in the western USA, could benefit from the use of nuclear power instead of power generated by natural gas combustion. This paper discusses the technical and economic aspects of integrating nuclear energy with oil sands operations and the development of oil shale resources. A high temperature gas reactor (HTGR) that produces heat in the form of high pressure steam (no electricity production) was selected as the nuclear power source for both fossil fuel resources. Both cases were based on 50,000 bbl/day output. The oil sands case was a steam-assisted, gravity-drainage (SAGD) operation located in the Canadian oil sands belt. The oil shale development was an in-situ oil shale retorting operation located in western Colorado, USA. The technical feasibility of the integrating nuclear power was assessed. The economic feasibility of each case was evaluated using a discounted cash flow, rate of return analysis. Integrating an HTGR to both the SAGD oil sands operation and the oil shale development was found to be technically feasible for both cases. In the oil sands case, integrating an HTGR eliminated natural gas combustion and associated CO2 emissions, although there were still some emissions associated with imported electrical power. In the in situ oil shale case, integrating an HTGR reduced CO2 emissions by 88% and increased natural gas production by 100%. Economic viabilities of both nuclear integrated cases were poorer than the non-nuclear-integrated cases when CO2 emissions were not taxed. However, taxing the CO2 emissions had a significant effect on the economics of the non-nuclear base cases, bringing them in line with the economics of the nuclear-integrated cases. As we move toward limiting CO2 emissions, integrating non-CO2-emitting energy sources to the development of energy-intense fossil fuel resources is becoming

  5. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology.

    Science.gov (United States)

    Liu, Ying; Lu, Zheming; Xu, Ruiping; Ke, Yang

    2016-02-02

    Integration of human papillomavirus (HPV) DNA into the host genome can be a driver mutation in cervical carcinoma. Identification of HPV integration at base resolution has been a longstanding technical challenge, largely due to sensitivity masking by HPV in episomes or concatenated forms. The aim was to enhance the understanding of the precise localization of HPV integration sites using an innovative strategy. Using HPV capture technology combined with next generation sequencing, HPV prevalence and the exact integration sites of the HPV DNA in 47 primary cervical cancer samples and 2 cell lines were investigated. A total of 117 unique HPV integration sites were identified, including HPV16 (n = 101), HPV18 (n = 7), and HPV58 (n = 9). We observed that the HPV16 integration sites were broadly located across the whole viral genome. In addition, either single or multiple integration events could occur frequently for HPV16, ranging from 1 to 19 per sample. The viral integration sites were distributed across almost all the chromosomes, except chromosome 22. All the cervical cancer cases harboring more than four HPV16 integration sites showed clinical diagnosis of stage III carcinoma. A significant enrichment of overlapping nucleotides shared between the human genome and HPV genome at integration breakpoints was observed, indicating that it may play an important role in the HPV integration process. The results expand on knowledge from previous findings on HPV16 and HPV18 integration sites and allow a better understanding of the molecular basis of the pathogenesis of cervical carcinoma.

  6. Weather information integration in transportation management center (TMC) operations.

    Science.gov (United States)

    2011-01-02

    This report presents the results of the third phase of an on-going FHWA study on weather integration in Transportation Management Center (TMC) operations. The report briefly describes the earlier phases of the integration study, summarizes the findin...

  7. Independent verification in operations at nuclear power plants: Summaries of site visits

    International Nuclear Information System (INIS)

    Donderi, D.C.; Smiley, A.; Ostry, D.J.; Moray, N.P.

    1995-09-01

    A critical review of approaches to independent verification in operations used in nuclear power plant quality assurance programs in other countries was conducted and are detailed in volume 1. This paper is a compilation of the visits to nuclear power plant sites to study independent verification in operations at sites in Canada, USA, Japan, United Kingdom, France and Germany. 3 tabs., 22 figs

  8. Demonstration of innovative monitoring technologies at the Savannah River Integrated Demonstration Site

    Energy Technology Data Exchange (ETDEWEB)

    Rossabi, J. [Westinghouse Savannah River Co., Aiken, SC (United States); Jenkins, R.A.; Wise, M.B. [Oak Ridge National Lab., TN (United States)] [and others

    1993-12-31

    The Department of Energy`s Office of Technology Development initiated an Integrated Demonstration Program at the Savannah River Site in 1989. The objective of this program is to develop, demonstrate, and evaluate innovative technologies that can improve present-day environmental restoration methods. The Integrated Demonstration Program at SRS is entitled ``Cleanup of Organics in Soils and Groundwater at Non-Arid Sites.`` New technologies in the areas of drilling, characterization, monitoring, and remediation are being demonstrated and evaluated for their technical performance and cost effectiveness in comparison with baseline technologies. Present site characterization and monitoring methods are costly, time-consuming, overly invasive, and often imprecise. Better technologies are required to accurately describe the subsurface geophysical and geochemical features of a site and the nature and extent of contamination. More efficient, nonintrusive characterization and monitoring techniques are necessary for understanding and predicting subsurface transport. More reliable procedures are also needed for interpreting monitoring and characterization data. Site characterization and monitoring are key elements in preventing, identifying, and restoring contaminated sites. The remediation of a site cannot be determined without characterization data, and monitoring may be required for 30 years after site closure.

  9. Demonstration of innovative monitoring technologies at the Savannah River Integrated Demonstration Site

    International Nuclear Information System (INIS)

    Rossabi, J.; Jenkins, R.A.; Wise, M.B.

    1993-01-01

    The Department of Energy's Office of Technology Development initiated an Integrated Demonstration Program at the Savannah River Site in 1989. The objective of this program is to develop, demonstrate, and evaluate innovative technologies that can improve present-day environmental restoration methods. The Integrated Demonstration Program at SRS is entitled ''Cleanup of Organics in Soils and Groundwater at Non-Arid Sites.'' New technologies in the areas of drilling, characterization, monitoring, and remediation are being demonstrated and evaluated for their technical performance and cost effectiveness in comparison with baseline technologies. Present site characterization and monitoring methods are costly, time-consuming, overly invasive, and often imprecise. Better technologies are required to accurately describe the subsurface geophysical and geochemical features of a site and the nature and extent of contamination. More efficient, nonintrusive characterization and monitoring techniques are necessary for understanding and predicting subsurface transport. More reliable procedures are also needed for interpreting monitoring and characterization data. Site characterization and monitoring are key elements in preventing, identifying, and restoring contaminated sites. The remediation of a site cannot be determined without characterization data, and monitoring may be required for 30 years after site closure

  10. Intra-operative application of optical coherence tomography with an operating microscope.

    Science.gov (United States)

    Just, T; Lankenau, E; Hüttmann, G; Pau, H W

    2009-09-01

    To introduce the use of optical coherence tomography with an operating microscope for intra-operative evaluation of the human larynx. A specially equipped operating microscope with integrated spectral domain optical coherence tomography apparatus was used during microlaryngoscopy. Technical improvements in optical coherence tomography equipment (e.g. pilot beam, variable focal distance, improved image quality and integration into an operating microscope) have enabled greater sensitivity and imaging speed and a non-contact approach. Spectral domain optical coherence tomography now enables a better correlation between optical coherence tomography images and histological findings. With this new technology, the precision of biopsy can be improved during microlaryngoscopy. Use of this new optical coherence tomography technology, integrated into an operating microscope, enables the surgeon to define the biopsy site location and resection plane precisely, while the optical zoom of the operating microscope can be used over the complete range.

  11. Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration.

    Science.gov (United States)

    Bridier-Nahmias, Antoine; Tchalikian-Cosson, Aurélie; Baller, Joshua A; Menouni, Rachid; Fayol, Hélène; Flores, Amando; Saïb, Ali; Werner, Michel; Voytas, Daniel F; Lesage, Pascale

    2015-05-01

    Mobile genetic elements are ubiquitous. Their integration site influences genome stability and gene expression. The Ty1 retrotransposon of the yeast Saccharomyces cerevisiae integrates upstream of RNA polymerase III (Pol III)-transcribed genes, yet the primary determinant of target specificity has remained elusive. Here we describe an interaction between Ty1 integrase and the AC40 subunit of Pol III and demonstrate that AC40 is the predominant determinant targeting Ty1 integration upstream of Pol III-transcribed genes. Lack of an integrase-AC40 interaction dramatically alters target site choice, leading to a redistribution of Ty1 insertions in the genome, mainly to chromosome ends. The mechanism of target specificity allows Ty1 to proliferate and yet minimizes genetic damage to its host. Copyright © 2015, American Association for the Advancement of Science.

  12. Overview of Nevada Test Site Radioactive and Mixed Waste Disposal Operations

    International Nuclear Information System (INIS)

    Carilli, J.T.; Krenzien, S.K.; Geisinger, R.G.; Gordon, S.J.; Quinn, B.

    2009-01-01

    The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office Environmental Management Program is responsible for carrying out the disposal of on-site and off-site generated low-level radioactive waste (LLW) and low-level radioactive mixed waste (MW) at the Nevada Test Site (NTS). Core elements of this mission are ensuring safe and cost-effective disposal while protecting workers, the public, and the environment. This paper focuses on the impacts of new policies, processes, and opportunities at the NTS related to LLW and MW. Covered topics include: the first year of direct funding for NTS waste disposal operations; zero tolerance policy for non-compliant packages; the suspension of mixed waste disposal; waste acceptance changes; DOE Consolidated Audit Program (DOECAP) auditing; the 92-Acre Area closure plan; new eligibility requirements for generators; and operational successes with unusual waste streams

  13. Operators guide: Atmospheric Release Advisory Capability (ARAC) site facility

    International Nuclear Information System (INIS)

    Lawver, B.S.

    1977-01-01

    In this report capabilities and services are described for the Atmospheric Release Advisory Capability (ARAC). The ARAC site system and its operating procedures and interactions with the ARAC central facility located at LLL is outlined. ARAC is designed to help officials at designated ERDA sites and other locations in estimating the effects of atmospheric releases of radionuclides or other hazardous materials by issuing real-time advisories to guide them in their planning

  14. Operators guide: Atmospheric Release Advisory Capability (ARAC) site facility

    International Nuclear Information System (INIS)

    Cassaro, E.; Lomonaco, L.

    1979-01-01

    The Atmospheric Release Advisory Capability (ARAC) is designed to help officials at designated DOE sites and other locations in estimating the effects of atmospheric releases of radionuclides or other hazardous materials by issuing real-time advisories to guide them in their planning. This report outlines the capabilities and sources of ARAC, and in more detail describes an ARAC Site Facility, its operating procedures and interactions with the ARAC Central Facility (ACF) located at LLL

  15. Integrated logistics management system for operation of machinery and equipment

    Directory of Open Access Journals (Sweden)

    Józef Frąś

    2014-09-01

    Full Text Available Background: The main issue in the operations of machinery and equipment, which is the subject of theoretical and empirical research is to provide high reliability and durability with qualitative post-trade services of machinery and equipment. Quality of service can be achieved through planned maintenance activities supported by computer technology. The article presents the concept of an integrated system of logistics management operation of machinery and equipment, especially special one for stationary transport equipment. At the outset, it emphasized the importance and essence of technological transport and storage systems storage in modern manufacturing enterprise. Then the objective and the method of research have been set. An essential part of deliberations in the article is the concept of integrated logistics management system operation for stationary transport equipment. Authors of this article have presented the results the implementation and operation of the system. The results are presented in a descriptive and graphic form. Methods: The purpose of this article is to present the concept of implementing an integrated logistics management system for operation of stationary transport equipment. It goes through combination of planning, event logging service, warehouse management in the field of spare parts, account and records of the cost of service activities. The paper presents an analysis and evaluation method of brainstorming a new approach to logistics management operation stationary transport equipment. Authors takes into account the specific conditions of use of transport equipment and conduct the service, which have a significant impact on the time and place of cost and service as well. It should be noted that the developed system has been implemented. It was also carried out an assessment of its functionality and efficiency as the new IT tool for logistics management operation. Results and conclusions: The paper presents a new

  16. Integrated Propulsion Data System Public Web Site

    Science.gov (United States)

    Hamilton, Kimberly

    2001-01-01

    The Integrated Propulsion Data System's (IPDS) focus is to provide technologically-advanced philosophies of doing business at SSC that will enhance the existing operations, engineering and management strategies and provide insight and metrics to assess their daily impacts, especially as related to the Propulsion Test Directorate testing scenarios for the 21st Century.

  17. M109 Family of Vehicles, Paladin Integrated Management (PIM): Operational Assessment of the Initial Operational Test and Evaluation (IOT and E)

    Science.gov (United States)

    2017-01-01

    Director, Operational Test and Evaluation M109 Family of Vehicles, Paladin Integrated Management (PIM) Operational Assessment of the... operational suitability, test adequacy, and survivability of the M109 Family of Vehicles (FoV), known as Paladin Integrated Management (PIM) Self...prevent the M109A7 SPH-equipped unit from completing its mission. The Paladin Integrated Management (PIM) Initial Operational Test and Evaluation

  18. Operational integration in primary health care: patient encounters and workflows.

    Science.gov (United States)

    Sifaki-Pistolla, Dimitra; Chatzea, Vasiliki-Eirini; Markaki, Adelais; Kritikos, Kyriakos; Petelos, Elena; Lionis, Christos

    2017-11-29

    Despite several countrywide attempts to strengthen and standardise the primary healthcare (PHC) system, Greece is still lacking a sustainable, policy-based model of integrated services. The aim of our study was to identify operational integration levels through existing patient care pathways and to recommend an alternative PHC model for optimum integration. The study was part of a large state-funded project, which included 22 randomly selected PHC units located across two health regions of Greece. Dimensions of operational integration in PHC were selected based on the work of Kringos and colleagues. A five-point Likert-type scale, coupled with an algorithm, was used to capture and transform theoretical framework features into measurable attributes. PHC services were grouped under the main categories of chronic care, urgent/acute care, preventive care, and home care. A web-based platform was used to assess patient pathways, evaluate integration levels and propose improvement actions. Analysis relied on a comparison of actual pathways versus optimal, the latter ones having been identified through literature review. Overall integration varied among units. The majority (57%) of units corresponded to a basic level. Integration by type of PHC service ranged as follows: basic (86%) or poor (14%) for chronic care units, poor (78%) or basic (22%) for urgent/acute care units, basic (50%) for preventive care units, and partial or basic (50%) for home care units. The actual pathways across all four categories of PHC services differed from those captured in the optimum integration model. Certain similarities were observed in the operational flows between chronic care management and urgent/acute care management. Such similarities were present at the highest level of abstraction, but also in common steps along the operational flows. Existing patient care pathways were mapped and analysed, and recommendations for an optimum integration PHC model were made. The developed web

  19. Oswer integrated health and safety standard operating practices. Directive

    International Nuclear Information System (INIS)

    1993-02-01

    The directive implements the OSWER (Office of Solid Waste and Emergency Response) Integrated Health and Safety Standards Operating Practices in conjunction with the OSHA (Occupational Safety and Health Act) Worker Protection Standards, replacing the OSWER Integrated Health and Safety Policy

  20. Site scientific mission plan for the southern Great Plains CART site, January--June 1998

    Energy Technology Data Exchange (ETDEWEB)

    Peppler, R.A.; Lamb, P.J. [Univ. of Oklahoma, Norman, OK (United States). Cooperative Inst. for Mesoscale Meteorological Studies; Sisterson, D.L. [Argonne National Lab., IL (United States). Environmental Research Div.

    1998-01-01

    The Southern Great Plains (SGP) Cloud and Radiation Testbed (CART) site is designed to help satisfy the data needs of the Atmospheric Radiation Measurement (ARM) Program Science Team. The primary purpose of this site scientific mission plan is to provide guidance for the development of plans for site operations. It also provides information on current plans to the ARM functional teams (Management Team, Data and Science Integration Team, Operations Team, and Instrument Team) and serves to disseminate the plans more generally within the ARM Program and among the members of the Science Team. This document includes a description of the operational status of the site and the primary site activities envisioned, together with information concerning approved and proposed intensive observation periods (IOPs). The primary users of this document are the Site operator, the Site Scientist Team (SST), the Science Team through the ARM Program science director, the ARM Program Experiment Center, and the aforementioned ARM Program functional teams. This plan is a living document that is updated and reissued every six months as the observational facilities are developed, tested, and augmented and as priorities are adjusted in response to developments in scientific planning and understanding.

  1. The systems integration operations/logistics model as a decision-support tool

    International Nuclear Information System (INIS)

    Miller, C.; Vogel, L.W.; Joy, D.S.

    1989-01-01

    Congress has enacted legislation specifying Yucca Mountain, Nevada, for characterization as the candidate site for the disposal of spent fuel and high-level wastes and has authorized a monitored retrievable storage (MRS) facility if one is warranted. Nevertheless, the exact configuration of the facilities making up the Federal Waste Management System (FWMS) was not specified. This has left the Office of Civilian Radioactive Waste Management (OCRWM) the responsibility for assuring the design of a safe and reliable disposal system. In order to assist in the analysis of potential configuration alternatives, operating strategies, and other factors for the FWMS and its various elements, a decision-support tool known as the systems integration operations/logistics model (SOLMOD) was developed. SOLMOD is a discrete event simulation model that emulates the movement and interaction of equipment and radioactive waste as it is processed through the FWMS - from pickup at reactor pools to emplacement. The model can be used to measure the impacts of different operating schedules and rules, system configurations, and equipment and other resource availabilities on the performance of processes comprising the FWMS and how these factors combine to determine overall system performance. SOLMOD can assist in identifying bottlenecks and can be used to assess capacity utilization of specific equipment and staff as well as overall system resilience

  2. Commutators of Integral Operators with Variable Kernels on Hardy ...

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 115; Issue 4. Commutators of Integral Operators with Variable Kernels on Hardy Spaces. Pu Zhang Kai Zhao. Volume 115 Issue 4 November 2005 pp 399-410 ... Keywords. Singular and fractional integrals; variable kernel; commutator; Hardy space.

  3. Airborne gamma spectrometry - towards integration of European operational capability

    International Nuclear Information System (INIS)

    Toivonen, H.

    2003-01-01

    Full text: A nuclear threat can take several forms. The fallout from nuclear weapons or from an accident in a nuclear power reactor may contaminate a large area (>>100,000 km 2 ) whereas the dispersion of single sources, either accidentally or deliberately (dirty bomb), contaminates a much smaller area, perhaps only a few thousand square kilometres or less. Airborne gamma spectrometry (AGS) plays an important role in providing detailed information an the dispersion of radioactive materials. AGS using a fixed-wing or a rotary-wing aircraft is at its best in fallout mapping and in searching for orphan sources. Plume tracking could be a third application but is very complex, and there is a risk of vehicle contamination, which would deteriorate mission capability in the later phases of an accident. Because of obvious advantages, unmanned aerial vehicles could be used to monitor the release rate at the site of an accident and perhaps the plume itself. The aim of the present paper is to discuss ways to utilize existing European airborne monitoring capabilities for multilateral assistance in an accident and to give some thoughts to how an integrated system could be developed to take into account various national measuring strategies. In a large-scale accident, it is to be expected that the European countries use their radiological resources to map their own territory. It is realistic to think of assistance by transferring equipment and staff to another country only in accident scenarios where a country or countries with essential AGS capability would not have been affected by the fallout. Various AGS survey results can be fused only if a common platform for data exchange is available. Formats and protocols have been developed for special cases (ECCOMAGS, Nuclear Fission Safety, 4 th and 5 th Framework Programmes) but there are no universal solutions applicable to different situations and Instruments. The hardware and software among the European AGS teams are tailor

  4. Remedial investigation/feasibility study work plan for the 100-BC-2 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1993-05-01

    This work plan and attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) remedial investigation/feasibility study (RI/FS) for the 100-BC-2 operable unit in the 100 Area of the Hanford Site. The 100 Area is one of four areas at the Hanford Site that are on the US Environmental Protection Agency's (EPA) National Priorities List under CERCLA. The 100-BC-2 operable unit is one of two source operable units in the 100-B/C Area (Figure ES-1). Source operable units are those that contain facilities and unplanned release sites that are potential sources of hazardous substance contamination. The 100-BC-2 source operable unit contains waste sites that were formerly in the 100-BC-2, 100-BC-3, and 100-BC-4 operable units. Because of their size and geographic location, the waste sites from these two operable units were added to 100-BC-2. This allows for a more efficient and effective investigation of the remaining 100-B/C Reactor area waste sites. The investigative approach to waste sites associated with the 100-BC-2 operable unit are listed in Table ES-1. The waste sites fall into three general categories: high priority liquid waste disposal sites, low priority liquid waste disposal sites, and solid waste burial grounds. Several sites have been identified as candidates for conducting an IRM. Two sites have been identified as warranting additional limited field sampling. The two sites are the 116-C-2A pluto crib, and the 116-C-2C sand filter

  5. Savannah River Site RCRA/CERCLA/NEPA integrated investigation case study

    International Nuclear Information System (INIS)

    Clark, D.R.; Thomas, R.; Wilson, M.P.

    1992-01-01

    The Savannah River Site (SRS) is a US Department of Energy facility placed on the Superfund National Priority List in 1989. Numerous past disposal facilities and contaminated areas are undergoing the integrated regulatory remediation process detailed in the draft SRS Federal Facility Agreement. This paper will discuss the integration of these requirements by highlighting the investigation of the D-Area Burning/Rubble Pits, a typical waste unit at SRS

  6. Integrated radiobioecological monitoring of Semipalatinsk test site: general approach

    International Nuclear Information System (INIS)

    Sejsebaev, A.T.; Shenal', K.; Bakhtin, M.M.; Kadyrova, N.Zh.

    2001-01-01

    This paper presents major research directions and general methodology for establishment of an integrated radio-bio-ecological monitoring system at the territory of the former Semipalatinsk nuclear test site. Also, it briefly provides the first results of monitoring the natural plant and animal populations at STS. (author)

  7. Application for Permit to Operate a Class II Solid Waste Disposal Site at the Nevada Test Site - U10c Disposal Site

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Programs

    2010-03-31

    The Nevada Test Site (NTS) is located approximately 105 km (65 mi) northwest of Las Vegas, Nevada. National Nuclear Security Administration Nevada Site Office (NNSA/NSO) is the federal lands management authority for the NTS and National Security Technologies LLC (NSTec) is the Management and Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS is posted with signs along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The site will be used for the disposal of refuse, rubbish, garbage, sewage sludge, pathological waste, Asbestos-Containing Material (ACM), industrial solid waste, hydrocarbon-burdened soil, hydrocarbon-burdened demolition and construction waste, and other inert waste (hereafter called permissible waste). Waste containing free liquids or regulated under Subtitle C of the Resource Conservation and Recovery Act (RCRA) will not be accepted for disposal at the site. Waste regulated under the Toxic Substance Control Act (TSCA), excluding Polychlorinated Biphenyl [PCB], Bulk Product Waste (see Section 6.2.5) and ACM (see Section 6.2.2.2) will not be accepted for disposal at the site. The disposal site will be used as the sole depository of permissible waste which is: (1) Generated by entities covered under the U.S. Environmental Protection Agency (EPA) Hazardous Waste Generator Identification Number for the NTS; (2) Generated at sites identified in the Federal Facilities Agreement and Consent Order (FFACO); (3) Sensitive records and media, including documents, vugraphs, computer disks, typewriter ribbons, magnetic tapes, etc., generated by NNSA/NSO or its contractors; (4) ACM generated by NNSA/NSO or its contractors according to Section 6.2.2.2, as necessary; (5) Hydrocarbon-burdened soil and solid waste from areas covered under the EPA Hazardous Waste Generator Identification Number for the NTS; (6) Other waste on a case-by-case concurrence by

  8. CLASSIFICATION OF THE MGR SITE OPERATIONS SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) site operations system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  9. Risk factors for surgical site infection following operative ankle fracture fixation.

    Science.gov (United States)

    Kelly, E G; Cashman, J P; Groarke, P J; Morris, S F

    2013-09-01

    Ankle fracture is a common injury and there is an increasingly greater emphasis on operative fixation. The purpose of the study was to determine the complication rate in this cohort of patients and, in doing so, determine risk factors which predispose to surgical site infection. A prospective cohort study was performed at a tertiary referral trauma center examining risk factors for surgical site infection in operatively treated ankle fractures. Univariate and multivariate analysis was performed. Female gender and advancing age were determined to be the risk factors in univariate analysis. Drain usage and peri-operative pyrexia were found to be significant for infection in multivariate analysis. This study allows surgeons to identify those at increased risk of infection and counsel them appropriately. It also allows for a high level of vigilance with regard to soft tissue handling intra-operatively in this higher risk group.

  10. US Department of Energy DOE Nevada Operations Office, Nevada Test Site: Underground safety and health standards

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The Nevada Test Site Underground Safety and Health Standards Working Group was formed at the direction of John D. Stewart, Director, Nevada Test Site Office in April, 1990. The objective of the Working Group was to compile a safety and health standard from the California Tunnel Safety Orders and OSHA for the underground operations at the NTS, (excluding Yucca Mountain). These standards are called the NTS U/G Safety and Health Standards. The Working Group submits these standards as a RECOMMENDATION to the Director, NTSO. Although the Working Group considers these standards to be the most integrated and comprehensive standards that could be developed for NTS Underground Operations, the intent is not to supersede or replace any relevant DOE orders. Rather the intent is to collate the multiple safety and health references contained in DOE Order 5480.4 that have applicability to NTS Underground Operations into a single safety and heath standard to be used in the underground operations at the NTS. Each portion of the standard was included only after careful consideration by the Working Group and is judged to be both effective and appropriate. The specific methods and rationale used by the Working Group are outlined as follows: The letter from DOE/HQ, dated September 28, 1990 cited OSHA and the CTSO as the safety and health codes applicable to underground operations at the NTS. These mandated codes were each originally developed to be comprehensive, i.e., all underground operations of a particular type (e.g., tunnels in the case of the CTSO) were intended to be adequately regulated by the appropriate code. However, this is not true; the Working Group found extensive and confusing overlap in the codes in numerous areas. Other subjects and activities were addressed by the various codes in cursory fashion or not at all.

  11. US Department of Energy DOE Nevada Operations Office, Nevada Test Site: Underground safety and health standards

    International Nuclear Information System (INIS)

    1993-05-01

    The Nevada Test Site Underground Safety and Health Standards Working Group was formed at the direction of John D. Stewart, Director, Nevada Test Site Office in April, 1990. The objective of the Working Group was to compile a safety and health standard from the California Tunnel Safety Orders and OSHA for the underground operations at the NTS, (excluding Yucca Mountain). These standards are called the NTS U/G Safety and Health Standards. The Working Group submits these standards as a RECOMMENDATION to the Director, NTSO. Although the Working Group considers these standards to be the most integrated and comprehensive standards that could be developed for NTS Underground Operations, the intent is not to supersede or replace any relevant DOE orders. Rather the intent is to collate the multiple safety and health references contained in DOE Order 5480.4 that have applicability to NTS Underground Operations into a single safety and heath standard to be used in the underground operations at the NTS. Each portion of the standard was included only after careful consideration by the Working Group and is judged to be both effective and appropriate. The specific methods and rationale used by the Working Group are outlined as follows: The letter from DOE/HQ, dated September 28, 1990 cited OSHA and the CTSO as the safety and health codes applicable to underground operations at the NTS. These mandated codes were each originally developed to be comprehensive, i.e., all underground operations of a particular type (e.g., tunnels in the case of the CTSO) were intended to be adequately regulated by the appropriate code. However, this is not true; the Working Group found extensive and confusing overlap in the codes in numerous areas. Other subjects and activities were addressed by the various codes in cursory fashion or not at all

  12. Operating Reserves and Wind Power Integration: An International Comparison; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Milligan, M.; Donohoo, P.; Lew, D.; Ela, E.; Kirby, B.; Holttinen, H.; Lannoye, E.; Flynn, D.; O' Malley, M.; Miller, N.; Eriksen, P. B.; Gottig, A.; Rawn, B.; Gibescu, M.; Lazaro, E. G.; Robitaille, A.; Kamwa, I.

    2010-10-01

    This paper provides a high-level international comparison of methods and key results from both operating practice and integration analysis, based on an informal International Energy Agency Task 25: Large-scale Wind Integration.

  13. The index of Fourier integral operators on manifolds with conical singularities

    International Nuclear Information System (INIS)

    Nazaikinskii, Vladimir E; Sternin, B Yu; Schulze, B-W

    2001-01-01

    We describe homogeneous canonical transformations of the cotangent bundle of a manifold with conical singular points and compute the index of an elliptic Fourier integral operator obtained by the quantization of such a transformation. The answer involves the index of an elliptic Fourier integral operator on a smooth manifold and the residues of the conormal symbol

  14. Shaft Siting and Configuration for Flexible Operating Mode

    International Nuclear Information System (INIS)

    Robert Boutin

    2001-01-01

    The purpose of this document as stated in the ''Technical Work Plan for Subsurface Design Section FY 01 Work Activities'' (CRWMS M and O 2001a, pg. 14) is to review and evaluate the most current concepts for shaft siting and configuration. The locations of the shaft sites will be evaluated in reference to the overall subsurface ventilation layout shown in Figure 1. The scope will include discussions on pad size requirements, shaft construction components such as collars, shaft stations, sumps, ground support and linings, head frames, fan ducting and facility equipping. In addition to these, shaft excavation methodologies and integration with the overall subsurface construction schedule will be described. The Technical Work Plan (TWP), (CRWMS M and O 2001a), for this document has been prepared in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering and Regulatory Compliance Activities''. This document will be prepared in accordance with AP-3.10Q, ''Analysis and Models''. This document contributes to Site Recommendation (SR). The intended use of this document is to provide an analysis for shaft siting and configuration criteria for subsequent construction. This document identifies preliminary design concepts that should not be used for procurement, fabrication, or construction

  15. Baseline risk assessment for the quarry residuals operable unit of the Weldon Spring Site, Weldon Spring, Missouri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The U.S. Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis. Cleanup of the site consists of several integrated components. The quarry residuals operable unit (QROU), consisting of the Weldon Spring quarry and its surrounding area, is one of four operable units being evaluated. In accordance with requirements of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, DOE is conducting a remedial investigation/feasibility study (RI/FS) to determine the proper response to address various contaminated media that constitute the QROU. Specifically, the operable unit consists of the following areas and media: the residual material remaining at the Weldon Spring quarry after removal of the pond water and the bulk waste; groundwater underlying the quarry and surrounding area; and other media located in the surrounding vicinity of the quarry, including surface water and sediment at Femme Osage Slough, Little Femme Osage Creek, and Femme Osage Creek. An initial evaluation of conditions at the quarry area identified remaining data requirements needed to support the conceptual site exposure and hydrogeological models. These data requirements are discussed in the RI/FS work plan issued in January 1994. Soil contamination located at a property adjacent to the quarry, referred to as Vicinity Property 9 (VP9), was originally part of the scope of the QROU, as discussed in the work plan. However, a decision was subsequently made to remediate this vicinity property as part of cleanup activities for the chemical plant operable unit, as provided for in the Record of Decision (ROD). Remediation of VP9 was completed in early 1996. Hence, this baseline risk assessment (BRA) does not address VP9.

  16. Baseline risk assessment for the quarry residuals operable unit of the Weldon Spring Site, Weldon Spring, Missouri

    International Nuclear Information System (INIS)

    1998-02-01

    The U.S. Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis. Cleanup of the site consists of several integrated components. The quarry residuals operable unit (QROU), consisting of the Weldon Spring quarry and its surrounding area, is one of four operable units being evaluated. In accordance with requirements of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, DOE is conducting a remedial investigation/feasibility study (RI/FS) to determine the proper response to address various contaminated media that constitute the QROU. Specifically, the operable unit consists of the following areas and media: the residual material remaining at the Weldon Spring quarry after removal of the pond water and the bulk waste; groundwater underlying the quarry and surrounding area; and other media located in the surrounding vicinity of the quarry, including surface water and sediment at Femme Osage Slough, Little Femme Osage Creek, and Femme Osage Creek. An initial evaluation of conditions at the quarry area identified remaining data requirements needed to support the conceptual site exposure and hydrogeological models. These data requirements are discussed in the RI/FS work plan issued in January 1994. Soil contamination located at a property adjacent to the quarry, referred to as Vicinity Property 9 (VP9), was originally part of the scope of the QROU, as discussed in the work plan. However, a decision was subsequently made to remediate this vicinity property as part of cleanup activities for the chemical plant operable unit, as provided for in the Record of Decision (ROD). Remediation of VP9 was completed in early 1996. Hence, this baseline risk assessment (BRA) does not address VP9

  17. Site scientific mission plan for the Southern Great Plains CART Site, January--June 1999

    Energy Technology Data Exchange (ETDEWEB)

    Peppler, R.A.; Sisterson, D.L.; Lamb, P.

    1999-03-10

    The Southern Great Plains (SGP) Cloud and Radiation Testbed (CART) site was designed to help satisfy the data needs of the Atmospheric Radiation Measurement (ARM) Program Science Team. This Site Scientific Mission Plan defines the scientific priorities for site activities during the six months beginning on January 1, 1999, and looks forward in lesser detail to subsequent six-month periods. The primary purpose of this document is to provide scientific guidance for the development of plans for site operations. It also provides information on current plans to the ARM functional teams (Management Team, Data and Science Integration Team [DSIT], Operations Team, and Instrument Team [IT]) and serves to disseminate the plans more generally within the ARM Program and among the members of the Science Team. This document includes a description of the operational status of the site and the primary site activities envisioned, together with information concerning approved and proposed intensive observation periods (IOPs). The primary users of this document are the site operator, the site program manager, the Site Scientist Team (SST), the Science Team through the ARM Program science director, the ARM Program Experiment Center, and the aforementioned ARM Program functional teams. This plan is a living document that is updated and reissued every six months as the observational facilities are developed, tested, and augmented and as priorities are adjusted in response to developments in scientific planning and understanding.

  18. Site scientific mission plan for the Southern Great Plains CART site: July--December 1998

    Energy Technology Data Exchange (ETDEWEB)

    Peppler, R.A.; Lamb, P. [Univ. of Oklahoma, Norman, OK (United States). Cooperative Inst. for Mesoscale Meteorological Studies; Sisterson, D.L. [Argonne National Lab., IL (United States). Environmental Research Div.

    1998-07-01

    The Southern Great Plains (SGP) Cloud and Radiation Testbed (CART) site was designed to help satisfy the data needs of the Atmospheric Radiation Measurement (ARM) Program Science Team. This Site Scientific Mission Plan defines the scientific priorities for site activities during the six months beginning on July 1, 1998, and looks forward in lesser detail to subsequent six-month periods. The primary purpose of this document is to provide scientific guidance for the development of plans for site operations. It also provides information on current plans to the ARM functional teams (Management Team, Data and Science Integration Team [DSIT], Operations Team, and Instrument Team [IT]) and serves to disseminate the plans more generally within the ARM Program and among the members of the Science Team. This document includes a description of the operational status of the site and the primary site activities envisioned, together with information concerning approved and proposed intensive observation periods (IOPs). The primary users of this document are the site operator, the site program manager, the Site Scientist Team (SST), the Science Team through the ARM Program science director, the ARM program Experiment Center, and the aforementioned ARM Program functional teams. This plan is a living document that is updated and reissued every six months as the observational facilities are developed, tested, and augmented and as priorities are adjusted in response to developments in scientific planning and understanding.

  19. On site PWR fuel inspection measurements for operational and design verification

    International Nuclear Information System (INIS)

    1996-01-01

    The on-site inspection of irradiated Pressurized Water Reactor (PWR) fuel and Non-Fuel Bearing Components (NFBC) is typically limited to visual inspections during refuelings using underwater TV cameras and is intended primarily to confirm whether the components will continue in operation. These inspections do not normally provide data for design verification nor information to benefit future fuel designs. Japanese PWR utilities and Nuclear Fuel Industries Ltd. designed, built, and performed demonstration tests of on-site inspection equipment that confirms operational readiness of PWR fuel and NFBC and also gathers data for design verification of these components. 4 figs, 3 tabs

  20. Integrated account of method, site selection and programme prior to the site investigation phase

    International Nuclear Information System (INIS)

    2000-12-01

    In order to dispose of the spent nuclear fuel in a safe manner, SKB plans to site a deep repository and an encapsulation plant with associated canister fabrication and transportation system. After an integrated evaluation of feasibility studies and other material, SKB will proceed with investigations of the rock and studies regarding establishment of the deep disposal system in the municipality of Oskarshamn or in Northern Uppland. The plans also include further study of the prospects for a deep repository in the municipality of Nykoeping. In the municipality of Oskarshamn, SKB plans further studies of a siting of the deep repository at Simpevarp. There SKB wants to initiate site investigations with test drilling. For the encapsulation plant, SKB wants to continue studying a siting at CLAB. In Northern Uppland, SKB plans to study two siting alternatives for the deep repository. One is Forsmark in the municipality of Oesthammar, where SKB wants to initiate a site investigation with test drilling. The other is Tierp north of Skutskaer, where SKB intends to start test drilling in an area north of Tierp. First, however, a suitable drilling area with possible transport solutions needs to be defined. This alternative requires the participation of the municipalities of both Tierp and Aelvkarleby. A siting of the encapsulation plant in Northern Uppland will also be studied. For the municipality of Nykoeping, SKB plans to conduct a new safety assessment for the Fjaellveden area, based on data from previous investigations as well as additional studies of how a deep repository could be arranged. SKB will thereby gather data from yet another geographic and geological region beyond those that are prioritized. No test drilling is planned in Nykoeping. The goal of the site investigation phase is to obtain all permits needed to build the planned facilities. It will take an estimated 7 - 8 years to assemble the requisite supporting material, carry out consultations, compile siting

  1. Concept of operations : Dallas Integrated Corridor Management (ICM) demonstration project.

    Science.gov (United States)

    2010-06-01

    This concept of operations (Con Ops) for the US-75 Integrated Corridor Management (ICM) Program has been developed as part of the US : Department of Transportation Integrated Corridor Management Initiative, which is an innovative research initiative ...

  2. Site Environmental Report for Calendar Year 1999. DOE Operations at The Boeing Company, Rocketdyne

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-09-01

    OAK A271 Site Environmental Report for Calendar Year 1999. DOE Operations at The Boeing Company, Rocketdyne. This Annual Site Environmental Report (ASER) for 1999 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of the Rocketdyne Santa Susana Field Laboratory (SSFL). In the past, these operations included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials under the former Atomics International Division. Other activities included the operation of large-scale liquid metal facilities for testing of liquid metal fast breeder components at the Energy Technology Engineering Center (ETEC), a government-owned, company-operated test facility within Area IV. All nuclear work was terminated in 1988, and subsequently, all radiological work has been directed toward decontamination and decommissioning (D&D) of the previously used nuclear facilities and associated site areas. Large-scale D&D activities of the sodium test facilities began in 1996. This Annual Site Environmental Report provides information showing that there are no indications of any potential impact on public health and safety due to the operations conducted at the SSFL. All measures and calculations of off-site conditions demonstrate compliance with applicable regulations, which provide for protection of human health and the environment.

  3. Site Environmental Report for Calendar Year 1999. DOE Operations at The Boeing Company, Rocketdyne

    International Nuclear Information System (INIS)

    None

    2000-01-01

    OAK A271 Site Environmental Report for Calendar Year 1999. DOE Operations at The Boeing Company, Rocketdyne. This Annual Site Environmental Report (ASER) for 1999 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of the Rocketdyne Santa Susana Field Laboratory (SSFL). In the past, these operations included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials under the former Atomics International Division. Other activities included the operation of large-scale liquid metal facilities for testing of liquid metal fast breeder components at the Energy Technology Engineering Center (ETEC), a government-owned, company-operated test facility within Area IV. All nuclear work was terminated in 1988, and subsequently, all radiological work has been directed toward decontamination and decommissioning (D and D) of the previously used nuclear facilities and associated site areas. Large-scale D and D activities of the sodium test facilities began in 1996. This Annual Site Environmental Report provides information showing that there are no indications of any potential impact on public health and safety due to the operations conducted at the SSFL. All measures and calculations of off-site conditions demonstrate compliance with applicable regulations, which provide for protection of human health and the environment

  4. Pre-operative and early post-operative factors associated with surgical site infection after laparoscopic sleeve gastrectomy.

    Science.gov (United States)

    Ruiz-Tovar, Jaime; Oller, Inmaculada; Llavero, Carolina; Arroyo, Antonio; Muñoz, Jose Luis; Calero, Alicia; Diez, María; Zubiaga, Lorea; Calpena, Rafael

    2013-08-01

    Surgical procedures on obese patients are expected to have a high incidence of surgical site infection (SSI). The identification of pre-operative or early post-operative risk factors for SSI may help the surgeon to identify subjects in risk and adequately optimize their status. We conducted a study of the association of comorbidities and pre- and post-operative analytical variables with SSI following laparoscopic sleeve gastrectomy for the treatment of morbid obesity. We performed a prospective study of all morbidly obese patients undergoing laparoscopic sleeve gastrectomy as a bariatric procedure between 2007 and 2011. An association of clinical and analytical variables with SSI was investigated. The study included 40 patients with a mean pre-operative body mass index (BMI) of 51.2±7.9 kg/m(2). Surgical site infections appeared in three patients (7.5%), of whom two had an intra-abdominal abscess located in the left hypochondrium and the third had a superficial incisional SSI. Pre-operatively, a BMI >45 kg/m(2) (OR 8.7; p=0.008), restrictive disorders identified by pulmonary function tests (OR 10.0; p=0.012), a serum total protein concentration 30 mcg/dL (OR 13.0; p=0.003), and a mean corpuscular volume (MCV) operative SSI. Post-operatively, a serum glucose >128 mg/dL (OR 4.7; p=0.012) and hemoglobin operative anemia and hyperglycemia as risk factors for SSI. In these situations, the surgeon must be aware of and seek to control these risk factors.

  5. Post-operative Wound Site Infection Caused by Nocardia species

    Directory of Open Access Journals (Sweden)

    Sunayana M. Jangla

    2018-04-01

    Full Text Available A61 year old diabetic female who was a known case of breast carcinoma and had undergone mastectomy was admitted with discharge from the post-operative wound site. Nocardia species was isolated from the discharge. She responded to treatment with trimethoprim-sulfamethoxazole.

  6. Identities for generalized fractional integral operators associated ...

    African Journals Online (AJOL)

    In this present work an attempt has been made to define two generalized fractional integral operators associated with products of analogues to Dirichlet averages and special functions. Discussions on the different aspects of the obtained results have been followed by utilization in finding out the images of multivariate ...

  7. The application of assessment principles to an operational low level waste disposal site in England

    International Nuclear Information System (INIS)

    McHugh, J.O.; Newstead, S.; Weedon, C.J.

    1988-01-01

    This paper reviews the current assessment principles utilized in England and discusses their application to the Drigg low-level Radioactive Waste Disposal Site. The Drigg Site was established in 1959 and the assessment principles were published in 1985; therefore, although the Drigg Site has operated successfully, the application of the assessment principles has caused changes in operations and the establishment of further site research by the Department of the Environment

  8. Common integration sites of published datasets identified using a graph-based framework

    Directory of Open Access Journals (Sweden)

    Alessandro Vasciaveo

    2016-01-01

    Full Text Available With next-generation sequencing, the genomic data available for the characterization of integration sites (IS has dramatically increased. At present, in a single experiment, several thousand viral integration genome targets can be investigated to define genomic hot spots. In a previous article, we renovated a formal CIS analysis based on a rigid fixed window demarcation into a more stretchy definition grounded on graphs. Here, we present a selection of supporting data related to the graph-based framework (GBF from our previous article, in which a collection of common integration sites (CIS was identified on six published datasets. In this work, we will focus on two datasets, ISRTCGD and ISHIV, which have been previously discussed. Moreover, we show in more detail the workflow design that originates the datasets.

  9. DNFSB Recommendation 94-1 Hanford Site Integrated Stabilization Management Plan. Volume 2

    International Nuclear Information System (INIS)

    Gerber, E.W.

    1995-10-01

    The Hanford Site Integrated Stabilization Management Plan (SISMP) was developed in support of the US Department of Energy's (DOE) Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1 Integrated Program Plan (IPP). Volume 1 of the SISMP identifies the technical scope and costs associated with Hanford Site plans to resolve concerns identified in DNFSB Recommendation 94-1. Volume 2 of the SISMP provides the Resource Loaded Integrated Schedules for Spent Nuclear Fuel Project and Plutonium Finishing Plant activities identified in Volume 1 of the SISMP. Appendix A provides the schedules and progress curves related to spent nuclear fuel management. Appendix B provides the schedules and progress curves related to plutonium-bearing material management. Appendix C provides programmatic logic diagrams that were referenced in Volume 1 of the SISMP

  10. 36 CFR 6.4 - Solid waste disposal sites not in operation on September 1, 1984.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Solid waste disposal sites... PARK SERVICE, DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.4 Solid waste disposal sites not in operation on September 1, 1984. (a) No person may operate...

  11. MOSE: A Demonstrator for an Automatic Operational System for the Optical Turbulence Forecast for ESO Sites

    Science.gov (United States)

    Masciadri, Elena; Lascaux, F.; Turchi, A.; Fini, L.

    2017-09-01

    "Most of the observations performed with new-generation ground-based telescopes are employing the Service Mode. To optimize the flexible-scheduling of scientific programs and instruments, the optical turbulence (OT) forecast is a must, particularly when observations are supported by adaptive optics (AO) and Interferometry. Reliable OT forecast are crucial to optimize the usage of AO and interferometric facilities which is not possible when using only optical measurements. Numerical techniques are the best placed to achieve such a goal. The MOSE project (MOdeling ESO Sites), co-funded by ESO, aimed at proving the feasibility of the forecast of (1) all the classical atmospheric parameters (such as temperature, wind speed and direction, relative humidity) and (2) the optical turbulence i.e. the CN 2 profiles and all the main integrated astro-climatic parameters derived from the CN 2 (the seeing, the isoplanatic angle, the wavefront coherence time) above the two ESO sites of Cerro Paranal and Cerro Armazones. The proposed technique is based on the use of a non-hydrostatic atmospheric meso-scale model and a dedicated code for the optical turbulence. The final goal of the project aimed at implementing an automatic system for the operational forecasts of the aforementioned parameters to support the astronomical observations above the two sites. MOSE Phase A and B have been completed and a set of dedicated papers have been published on the topic. Model performances have been extensively quantified with several dedicated figures of merit and we proved that our tool is able to provide reliable forecasts of optical turbulence and atmospheric parameters with very satisfactory score of success. This should guarantee us to make a step ahead in the framework of the Service Mode of new generation telescopes. A conceptual design as well as an operational plan of the automatic system has been submitted to ESO as integral part of the feasibility study. We completed a negotiation with

  12. Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference.

    Directory of Open Access Journals (Sweden)

    Geoffrey R Bennett

    Full Text Available Host base excision repair (BER proteins that repair oxidative damage enhance HIV infection. These proteins include the oxidative DNA damage glycosylases 8-oxo-guanine DNA glycosylase (OGG1 and mutY homolog (MYH as well as DNA polymerase beta (Polβ. While deletion of oxidative BER genes leads to decreased HIV infection and integration efficiency, the mechanism remains unknown. One hypothesis is that BER proteins repair the DNA gapped integration intermediate. An alternative hypothesis considers that the most common oxidative DNA base damages occur on guanines. The subtle consensus sequence preference at HIV integration sites includes multiple G:C base pairs surrounding the points of joining. These observations suggest a role for oxidative BER during integration targeting at the nucleotide level. We examined the hypothesis that BER repairs a gapped integration intermediate by measuring HIV infection efficiency in Polβ null cell lines complemented with active site point mutants of Polβ. A DNA synthesis defective mutant, but not a 5'dRP lyase mutant, rescued HIV infection efficiency to wild type levels; this suggested Polβ DNA synthesis activity is not necessary while 5'dRP lyase activity is required for efficient HIV infection. An alternate hypothesis that BER events in the host genome influence HIV integration site selection was examined by sequencing integration sites in OGG1 and MYH null cells. In the absence of these 8-oxo-guanine specific glycosylases the chromatin elements of HIV integration site selection remain the same as in wild type cells. However, the HIV integration site sequence preference at G:C base pairs is altered at several positions in OGG1 and MYH null cells. Inefficient HIV infection in the absence of oxidative BER proteins does not appear related to repair of the gapped integration intermediate; instead oxidative damage repair may participate in HIV integration site preference at the sequence level.

  13. Distributed Energy Systems Integration and Demand Optimization for Autonomous Operations and Electric Grid Transactions

    Energy Technology Data Exchange (ETDEWEB)

    Ghatikar, Girish [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Greenlots, San Francisco, CA (United States); Mashayekh, Salman [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Stadler, Michael [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Center for Energy and Innovation Technologies (Austria); Yin, Rongxin [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Liu, Zhenhua [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-11-29

    Distributed power systems in the U.S. and globally are evolving to provide reliable and clean energy to consumers. In California, existing regulations require significant increases in renewable generation, as well as identification of customer-side distributed energy resources (DER) controls, communication technologies, and standards for interconnection with the electric grid systems. As DER deployment expands, customer-side DER control and optimization will be critical for system flexibility and demand response (DR) participation, which improves the economic viability of DER systems. Current DER systems integration and communication challenges include leveraging the existing DER and DR technology and systems infrastructure, and enabling optimized cost, energy and carbon choices for customers to deploy interoperable grid transactions and renewable energy systems at scale. Our paper presents a cost-effective solution to these challenges by exploring communication technologies and information models for DER system integration and interoperability. This system uses open standards and optimization models for resource planning based on dynamic-pricing notifications and autonomous operations within various domains of the smart grid energy system. It identifies architectures and customer engagement strategies in dynamic DR pricing transactions to generate feedback information models for load flexibility, load profiles, and participation schedules. The models are tested at a real site in California—Fort Hunter Liggett (FHL). Furthermore, our results for FHL show that the model fits within the existing and new DR business models and networked systems for transactive energy concepts. Integrated energy systems, communication networks, and modeling tools that coordinate supply-side networks and DER will enable electric grid system operators to use DER for grid transactions in an integrated system.

  14. Site scientific mission plan for the southern Great Plain CART site July-December 1997.

    Energy Technology Data Exchange (ETDEWEB)

    Lamb, P.J.; Peppler, R.A.; Sisterson, D.L.

    1997-08-28

    The Southern Great Plains (SGP) Cloud and Radiation Testbed (CART) site is designed to help satisfy the data needs of the Atmospheric Radiation Measurement (ARM) Program Science Team. This document defines the scientific priorities for site activities during the six months beginning on July 1, 1997, and looks forward in lesser detail to subsequent six-month periods. The primary purpose of this Site Scientific Mission Plan is to provide guidance for the development of plans for site operations. It also provides information on current plans to the ARM functional teams (Management Team, Data and Science Integration Team [DSIT], Operations Team, Instrument Team [IT], and Campaign Team) and serves to disseminate the plans more generally within the ARM Program and among the members of the Science Team. This document includes a description of the operational status of the site and the primary site activities envisioned, together with information concerning approved and proposed intensive observation periods (IOPs). The primary users of this document are the site operator, the Site Scientist Team (SST), the Science Team through the ARM Program science director, the ARM Program Experiment Center, and the aforementioned ARM Program functional teams. This plan is a living document that is updated and reissued every six months as the observational facilities are developed, tested, and augmented and as priorities are adjusted in response to developments in scientific planning and understanding.

  15. Operations and maintenance plan : Dallas Integrated Corridor Management (ICM) demonstration project.

    Science.gov (United States)

    2014-01-01

    This Operations and Maintenance (O&M) Plan describes how the Integrated Corridor Management System (ICMS) will be used in daily transportation operations and maintenance activities. The Plan addresses the activities needed to effectively operate the ...

  16. Integrated fate and toxicity assessment for site contaminants

    International Nuclear Information System (INIS)

    MacDonell, Margaret; Peterson, John; Finster, Molly; Douglas, R.

    2007-01-01

    Understanding the fate and toxicity of environmental contaminants is essential to framing practical management decisions. Forms and bioavailable concentrations often change over time due to natural physical, chemical, and biological processes. For some sites, hundreds of contaminants may be of initial interest, and even small projects can involve a substantial number of contaminants. With multiple assessments common, attention to effectiveness and efficiency is important, and integrating fate and toxicity information provides a valuable way to focus the analyses. Fate assessments help identify what forms may be present where and when, while toxicity information indicates what health effects could result if people were exposed. The integration process is illustrated by an application for the Hanford site, to support long-term management decisions for the cesium and strontium capsules. Fate data, health-based benchmarks, and related toxicity information were effectively combined to indicate performance targets for chemicals and radionuclides identified for capsule leachate that could migrate to groundwater. More than 50 relevant benchmarks and toxicity context were identified for 15 of the 17 study contaminants; values for chronic drinking water exposure provided the common basis for selected indicators. For two chemicals, toxicity information was identified from the scientific literature to guide the performance targets. (authors)

  17. Total Site Integration and paper machine technologies; Total site integration ja paperikoneteknologia - PMST 02

    Energy Technology Data Exchange (ETDEWEB)

    Puumalainen, T.; Kaijaluoto, S.; Tervonen, P.; Edelmann, K. [VTT Energy, Jyvaeskylae (Finland)

    1998-12-31

    During the last 30 years the production capacity of a paper machine has tripled. The fastest machines of today run over about 1600 m/min, the web width being around 10 m. The desire to further increase the production capacity is leading to more expensive paper machines and to larger buildings, if current pressing and drying techniques are used. New pressing and drying techniques will decrease the need of thermal energy. Closed water cycles reduce the need of secondary heat abundantly available from the dryer section based on cylinder drying. Total Site Integration studies are required when the effect of new process concepts are to be evaluated against energy efficiency and environmental impacts. A proto type tool has been developed and the effect of new paper machine concepts on energy consumption have been analysed. The utilisation possibilities of the surplus energy will be studied later in the course of this project. (orig.)

  18. Total Site Integration and paper machine technologies; Total site integration ja paperikoneteknologia - PMST 02

    Energy Technology Data Exchange (ETDEWEB)

    Puumalainen, T; Kaijaluoto, S; Tervonen, P; Edelmann, K [VTT Energy, Jyvaeskylae (Finland)

    1999-12-31

    During the last 30 years the production capacity of a paper machine has tripled. The fastest machines of today run over about 1600 m/min, the web width being around 10 m. The desire to further increase the production capacity is leading to more expensive paper machines and to larger buildings, if current pressing and drying techniques are used. New pressing and drying techniques will decrease the need of thermal energy. Closed water cycles reduce the need of secondary heat abundantly available from the dryer section based on cylinder drying. Total Site Integration studies are required when the effect of new process concepts are to be evaluated against energy efficiency and environmental impacts. A proto type tool has been developed and the effect of new paper machine concepts on energy consumption have been analysed. The utilisation possibilities of the surplus energy will be studied later in the course of this project. (orig.)

  19. Integrated co-operative governance in the context of sustainable development

    Directory of Open Access Journals (Sweden)

    Eric Nealer

    2011-07-01

    Keywords:Sustainable development, governance, co-operative governance, integrated,organising, and communication. Disciplines:Public Administration, Public Management, Social Welfare, Environmental Management, Municipal public service delivery, Social Development, Organisational Behaviour, Co-operative Governance, Communication, Sustainable Development, Sustainable Organisational Development

  20. DNFSB Recommendation 94-1 Hanford site integrated stabilization management plan, volumes 1 and 2

    International Nuclear Information System (INIS)

    Gerber, E.W.

    1996-01-01

    This document comprises the Hanford Site Integrated Stabilization Management Plan (SISMP). This document describes the DOE's plans at the Hanford Site to address concerns identified in Defense Nuclear Facilites Safety Board (DNFSB) Recommendation 94-1. This document also identifies plans for other spent nuclear fuel (SNF) inventories at the Hanford Site which are not within the scope of DNFSB Recommendation 94-1 for reference purposes because of their interrelationship with plans for SNF within the scope of DNFSB Recommendation 94-1. The SISMP was also developed to assist DOE in initial formulation of the Research and Development Plan and the Integrated Facilities Plan

  1. Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase.

    Science.gov (United States)

    Nkrumah, Louis J; Muhle, Rebecca A; Moura, Pedro A; Ghosh, Pallavi; Hatfull, Graham F; Jacobs, William R; Fidock, David A

    2006-08-01

    Here we report an efficient, site-specific system of genetic integration into Plasmodium falciparum malaria parasite chromosomes. This is mediated by mycobacteriophage Bxb1 integrase, which catalyzes recombination between an incoming attP and a chromosomal attB site. We developed P. falciparum lines with the attB site integrated into the glutaredoxin-like cg6 gene. Transfection of these attB(+) lines with a dual-plasmid system, expressing a transgene on an attP-containing plasmid together with a drug resistance gene and the integrase on a separate plasmid, produced recombinant parasites within 2 to 4 weeks that were genetically uniform for single-copy plasmid integration. Integrase-mediated recombination resulted in proper targeting of parasite proteins to intra-erythrocytic compartments, including the apicoplast, a plastid-like organelle. Recombinant attB x attP parasites were genetically stable in the absence of drug and were phenotypically homogeneous. This system can be exploited for rapid genetic integration and complementation analyses at any stage of the P. falciparum life cycle, and it illustrates the utility of Bxb1-based integrative recombination for genetic studies of intracellular eukaryotic organisms.

  2. The effects of low internal integration between purchasing and operations on suppliers’ resource mobilization

    DEFF Research Database (Denmark)

    Ellegaard, Chris; Koch, Christian

    2012-01-01

    A company that suffers from low internal integration between corporate functions performs worse than its more integrated competitors, leaving it in a position of competitive disparity. This paper reports on an investigation of the effects of internal integration between purchasing and operations...... on the mobilization of supplier resources. Low internal integration generates uncoordinated operations and purchasing behaviors that negatively affect supplier resource mobilization. We find that the lack of operations support for eight major purchasing initiatives in a construction company negatively affects...

  3. Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome

    Directory of Open Access Journals (Sweden)

    Pin Cui

    2016-03-01

    Full Text Available Background. Retroviral integration into the host germline results in permanent viral colonization of vertebrate genomes. The koala retrovirus (KoRV is currently invading the germline of the koala (Phascolarctos cinereus and provides a unique opportunity for studying retroviral endogenization. Previous analysis of KoRV integration patterns in modern koalas demonstrate that they share integration sites primarily if they are related, indicating that the process is currently driven by vertical transmission rather than infection. However, due to methodological challenges, KoRV integrations have not been comprehensively characterized. Results. To overcome these challenges, we applied and compared three target enrichment techniques coupled with next generation sequencing (NGS and a newly customized sequence-clustering based computational pipeline to determine the integration sites for 10 museum Queensland and New South Wales (NSW koala samples collected between the 1870s and late 1980s. A secondary aim of this study sought to identify common integration sites across modern and historical specimens by comparing our dataset to previously published studies. Several million sequences were processed, and the KoRV integration sites in each koala were characterized. Conclusions. Although the three enrichment methods each exhibited bias in integration site retrieval, a combination of two methods, Primer Extension Capture and hybridization capture is recommended for future studies on historical samples. Moreover, identification of integration sites shows that the proportion of integration sites shared between any two koalas is quite small.

  4. Defense waste management operations at the Nevada Test Site

    International Nuclear Information System (INIS)

    Williams, R.E.; Kendall, E.W.

    1988-01-01

    Waste management activities were initiated at the Nevada Test Site (NTS) to dispose of low-level wastes (LLW) produced by the Department of Energy's (DOE's) weapons testing program. Disposal activities have expanded from the burial of atmospheric weapons testing debris to demonstration facilities for greater-than-Class C (GTCC) waste, transuranic (TRU) waste storage and certification, and the development of a mixed waste (MW) facility. Site specific operational research projects support technology development required for the various disposal facilities. The annual cost of managing the facilities is about $6 million depending on waste volumes and types

  5. Space station operations task force. Panel 3 report: User development and integration

    Science.gov (United States)

    1987-01-01

    The User Development and Integration Panel of the Space Station Operations Task Force was chartered to develop concepts relating to the operations of the Space Station manned base and the platforms, user accommodation and integration activities. The needs of the user community are addressed in the context with the mature operations phase of the Space Station. Issues addressed include space station pricing options, marketing strategies, payload selection and resource allocation options, and manifesting techniques.

  6. Development of OSSA(Operation Service Support Agreement) Simulator and Site Acceptance Test

    Energy Technology Data Exchange (ETDEWEB)

    Park, DaeSeung; Ahn, Sung-Jin; Lee, Jong-Beom [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    Building the nuclear power plant is on the schedule, remaining question is who could operate the NPP after the construction is finished. OSSA is known as Operation Service Support Agreement, it is the contract between KHNP(Korea Hydro and Nuclear Power Co.,) and ENEC(Emirates Nuclear Energy Corporation) for United Arab Emirates Nuclear Power Plant operations support. The contract is mostly about the safety and reliability operations and as well as of the training of UAE operators to have better experiences. UAE operators needed to be trained and tested before they come to UAE for operate the NPP. The OSSA simulator was built because operator shall not make any mistakes even if the plant is not yet constructed. Simulator Training is a key for getting experiences without operating the actual plant, because the nuclear power plant never used as the test in real situations. Operators’ requirement is to have more than 2 years at site experiences and also they have to be trained 5 to 8 months of the training. The experience such as the site acceptance test will lead the future nuclear industry to meet the global standard and to lead the safety of the NPP. Under the OSSA agreement 400 KHNP experts will support the operations. Most of the operators were trained at the OSSA simulator which is most reliable simulator that can demonstrate satisfactory performance for the simulator.

  7. A program for performing angular integrations for transition operators

    International Nuclear Information System (INIS)

    Froese Fischer, C.; Godefroid, M.R.; Hibbert, A.

    1991-01-01

    The MCHF-MLTPOL program performs the angular integrations necessary for expressing the matrix elements of transition operators, E1, E2, ..., or M1, M2, ..., as linear combinations of radial integrals. All matrix elements for transitions between two lists of configuration states will be evaluated. A limited amount of non-orthogonality is allowed between orbitals of the initial and final state. (orig.)

  8. Special Operations can make a difference in integrated conflict prevention

    DEFF Research Database (Denmark)

    Jensen, Lars H. Ehrensvärd

    The fifth brief in the series about special operations highlights the possible strategic role of special operations in connection with Denmark's revitalized vision of integration of the state's instruments to create security through preventive stabilization efforts. The brief offers suggestion...

  9. Joint-operation in water resources project in Indonesia: Integrated or non-integrated

    Science.gov (United States)

    Ophiyandri, Taufika; Istijono, Bambang; Hidayat, Benny

    2017-11-01

    The construction of large water resources infrastructure project often involved a joint-operation (JO) project between two or more construction companies. The form of JO can be grouped into two categories - an integrated type and a non-integrated type. This paper investigates the reason of forming a JO project made by companies. The specific advantages and problems of JO project is also analysed in this paper. In order to achieve the objectives, three water resources infrastructure projects were selected as case studies. Data was gathered by conducting 11 semi-structured interviews to project owners, contractor managers, and project staffs. Data was analysed by means of content analysis. It was found that the most fundamental factor to form a JO is to win a competition or tender. An integrated model is in favour because it can reduce overhead costs and has a simple management system, while a non-integrated model is selected because it can avoid a sleeping partner and make contractor more responsible for their own job.

  10. Solving Abel’s Type Integral Equation with Mikusinski’s Operator of Fractional Order

    Directory of Open Access Journals (Sweden)

    Ming Li

    2013-01-01

    Full Text Available This paper gives a novel explanation of the integral equation of Abel’s type from the point of view of Mikusinski’s operational calculus. The concept of the inverse of Mikusinski’s operator of fractional order is introduced for constructing a representation of the solution to the integral equation of Abel’s type. The proof of the existence of the inverse of the fractional Mikusinski operator is presented, providing an alternative method of treating the integral equation of Abel’s type.

  11. 78 FR 12358 - UBS Financial Services, Inc., Wealth Management Americas Operations, Including On-Site Leased...

    Science.gov (United States)

    2013-02-22

    ..., Inc., Wealth Management Americas Operations, Including On-Site Leased Workers From Leafstone... Services, Inc., Wealth Management Americas Operations (UBS), Weehawken, New Jersey. The workers are engaged... to include all leased workers on-site at UBS Financial Services, Inc., Wealth Management Americas...

  12. An operator expansion technique for path integral analysis

    International Nuclear Information System (INIS)

    Tsvetkov, I.V.

    1995-01-01

    A new method of path integral analysis in the framework of a power series technique is presented. The method is based on the operator expansion of an exponential. A regular procedure to calculate the correction terms is found. (orig.)

  13. Site scientific mission plan for the Southern Great Plains CART site: January 1997--June 1997

    Energy Technology Data Exchange (ETDEWEB)

    Peppler, R.A.; Lamb, P.J. [Univ. of Oklahoma, Norman, OK (United States). Cooperative Institute for Mesoscale Meteorological Studies; Sisterson, D.L. [Argonne National Lab., IL (United States)

    1997-01-01

    The Southern Great Plains (SGP) Cloud and Radiation Testbed (CART) site is designed to help satisfy the data needs of the Atmospheric Radiation Measurement (ARM) Program Science Team. This document defines the scientific priorities for site activities during the six months beginning on January 1, 1997, and looks forward in lesser detail to subsequent six-month periods. The primary purpose of this Site Scientific Mission Plan is to provide guidance for the development of plans for site operations. It also provides information on current plans to the ARM functional teams (Management Team, Data and Science Integration Team [DSIT], Operations Team, Instrument Team [IT], and Campaign Team) and serves to disseminate the plans more generally within the ARM Program and among the members of the Science Team. This document includes a description of the operational status of the site and the primary site activities envisioned, together with information concerning approved and proposed intensive observation periods (IOPs). The primary users of this document are the site operator, the Site Scientist Team (SST), the Science Team through the ARM Program science director, the ARM Program Experiment Center, and the aforementioned ARM Program functional teams. This plan is a living document that is updated and reissued every six months as the observational facilities are developed, tested, and augmented and as priorities are adjusted in response to developments in scientific planning and understanding.

  14. Savannah River Site peer evaluator standards: Operator assessment for restart

    International Nuclear Information System (INIS)

    1990-01-01

    Savannah River Site has implemented a Peer Evaluator program for the assessment of certified Central Control Room Operators, Central Control Room Supervisors and Shift Technical Engineers prior to restart. This program is modeled after the nuclear Regulatory Commission's (NRC's) Examiner Standard, ES-601, for the requalification of licensed operators in the commercial utility industry. It has been tailored to reflect the unique differences between Savannah River production reactors and commercial power reactors

  15. Pre operational background radiation monitoring around Kudankulam Nuclear Power Project site - a decade long experience

    International Nuclear Information System (INIS)

    Vijayakumar, B.; George, Thomas; Sundara Rajan, P.; Selvi, B.S.; Balamurugan, M.; Pandit, G.G.; Ravi, P.M.; Tripathi, R.M.

    2014-01-01

    Pre-operational environmental background radiation monitoring around nuclear power plants is very important to understand baseline values existing in the site and also to identify any hot spots of naturally occurring high background radiation areas and their sources. These baseline measurements will act as a benchmark for future comparison after the reactors go into operation. The radiation measurements are continued during the operational phase of the plant and the results are compared to see whether there is any impact of the operation of the plant on the environment. A comprehensive background radiation monitoring plan has been in vogue at site from 2004 to meet this objective. This paper describes the different monitoring strategies adopted around Kudankulam Nuclear Power Project site and throws light on the pre operational background radiation levels in the environment

  16. Environmental Assessment for the construction and operation of the Health Physics Site Support Facility on the Savannah River Site

    International Nuclear Information System (INIS)

    1995-07-01

    DOE has prepared an environmental assessment for the proposed construction and operation of the Health Physics Site Support Facility on the Savannah River Site. This (new) facility would meet requirements of the site radiological protection program and would ensure site compliance with regulations. It was determined that the proposed action is not a major Federal action significantly affecting the quality of the environment within the meaning of NEPA. Therefore, a finding of no significant impact is made, and no environmental impact statement is needed

  17. BIM-Integrated Construction Operation Simulation for Just-In-Time Production Management

    Directory of Open Access Journals (Sweden)

    WoonSeong Jeong

    2016-10-01

    Full Text Available Traditional construction planning, which depends on historical data and heuristic modification, prevents the integration of managerial details such as productivity dynamics. Specifically, the distance between planning and execution brings cost overruns and duration extensions. To minimize variations, this research presents a Building Information Modeling (BIM-integrated simulation framework for predicting productivity dynamics at the construction planning phase. To develop this framework, we examined critical factors affecting productivity at the operational level, and then forecast the productivity dynamics. The resulting plan includes specific commands for retrieving the required information from BIM and executing operation simulations. It consists of the following steps: (1 preparing a BIM model to produce input data; (2 composing a construction simulation at the operational level; and (3 obtaining productivity dynamics from the BIM-integrated simulation. To validate our framework, we applied it to a structural steel model; this was due to the significance of steel erections. By integrating BIM with construction operation simulations, we were able to create reliable construction plans that adapted to project changes. Our results show that the developed framework facilitates the reliable prediction of productivity dynamics, and can contribute to improved schedule reliability, optimized resource allocation, cost savings associated with buffers, and reduced material waste.

  18. NASA's ATM Technology Demonstration-1: Integrated Concept of Arrival Operations

    Science.gov (United States)

    Baxley, Brian T.; Swenson, Harry N.; Prevot, Thomas; Callantine, Todd J.

    2012-01-01

    This paper describes operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (ConOps) demonstration will integrate three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to touchdown. It also enables aircraft to conduct Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and implantation into an operational environment. Goals of the ATD-1 demonstration include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.

  19. Rocketdyne Propulsion and Power DOE Operations annual site environmental report 1997

    International Nuclear Information System (INIS)

    Robinson, K.S.

    1998-01-01

    This annual report discusses environmental monitoring at two manufacturing and test sites operated in the Los Angeles area by Rocketdyne Propulsion and Power of Boeing North American, Inc. These are identified as Area 4 of the SSFL and the De Soto site. These sites have been used for research and development (R and D), engineering, and testing in a broad range of technical fields primarily in energy research and nuclear reactor technology. The De Soto site had research and development laboratories involved with nuclear research. This work was terminated in 1995 and only D and D activities will have potential for impact on the environment. Since 1956, Area 4 has been used for work with nuclear materials, including fabricating nuclear reactor fuels, testing nuclear reactors, and dissembling used fuel elements. This work ended in 1988 and subsequent efforts have been directed toward decommissioning and decontamination of the former nuclear facilities. The primary purpose of this report is to present information on environmental and effluent monitoring of DOE-sponsored activities to the regulatory agencies responsible for oversight. Information presented here concentrates on Area 4 at SSFL, which is the only area at SSFL where DOE operations were performed

  20. Characterization Report Operational Closure Covers for the Area 5 Radioactive Waste Management Site at the Nevada Test Site

    International Nuclear Information System (INIS)

    Bechtel Nevada Geotechnical Sciences

    2005-01-01

    Bechtel Nevada (BN) manages two low-level Radioactive Waste Management Sites (RWMSs) at the Nevada Test Site (NTS) for the U.S. Department of Energy (DOE) National Nuclear Security Administration Nevada Site Office (NNSA/NSO). The Area 3 RWMS is located in south-central Yucca Flat and the Area 5 RWMS is located about 15 miles south, in north-central Frenchman Flat. Though located in two separate topographically closed basins, they are similar in climate and hydrogeologic setting. The Area 5 RWMS uses engineered shallow-land burial cells to dispose of packaged waste, while the Area 3 RWMS uses subsidence craters formed from underground testing of nuclear weapons for the disposal of packaged and unpackaged bulk waste. Over the next several decades, most waste disposal units at both the Area 3 and Area 5 RWMSs are anticipated to be closed. Closure of the Area 3 and Area 5 RWMSs will proceed through three phases: operational closure, final closure, and institutional control. Many waste disposal units at the Area 5RWMS are operationally closed and final closure has been placed on one unit at the Area 3 RWMS (U-3ax/bl). Because of the similarities between the two sites (e.g., type of wastes, environmental factors, operational closure cover designs, etc.), many characterization studies and data collected at the Area 3 RWMS are relevant and applicable to the Area 5 RWMS. For this reason, data and closure strategies from the Area 3 RWMS are referred to as applicable. This document is an interim Characterization Report - Operational Closure Covers, for the Area 5 RWMS. The report briefly describes the Area 5 RWMS and the physical environment where it is located, identifies the regulatory requirements, reviews the approach and schedule for closing, summarizes the monitoring programs, summarizes characterization studies and results, and then presents conclusions and recommendations

  1. Optimized probes for dose rate measurements at local government sites and in emergency planning zones and their integration into measurement networks

    International Nuclear Information System (INIS)

    Kuca, Petr; Helebrant, Jan; Cespirova, Irena; Judas, Libor; Skala, Lukas

    2015-01-01

    The results of a security project aimed at the development of a radiation situation monitoring system using optimized probes for dose rate measurements are described. The system is suitable for use at local government sites as well as at other sites. The system includes dose rate measurement probes with the variable configuration functionality (detection part), equipment for data transfer to a central workplace (communication part) and application for collection, storage and administration of the results and their presentation at a website (presentation part). The dosimetric and other operational properties of the probes were tested and the feasibility of their integration into measurement networks using the IMS central application was examined. (orig.)

  2. Site descriptive modelling - strategy for integrated evaluation

    International Nuclear Information System (INIS)

    Andersson, Johan

    2003-02-01

    The current document establishes the strategy to be used for achieving sufficient integration between disciplines in producing Site Descriptive Models during the Site Investigation stage. The Site Descriptive Model should be a multidisciplinary interpretation of geology, rock mechanics, thermal properties, hydrogeology, hydrogeochemistry, transport properties and ecosystems using site investigation data from deep bore holes and from the surface as input. The modelling comprise the following iterative steps, evaluation of primary data, descriptive and quantitative modelling (in 3D), overall confidence evaluation. Data are first evaluated within each discipline and then the evaluations are checked between the disciplines. Three-dimensional modelling (i.e. estimating the distribution of parameter values in space and its uncertainty) is made in a sequence, where the geometrical framework is taken from the geological model and in turn used by the rock mechanics, thermal and hydrogeological modelling etc. The three-dimensional description should present the parameters with their spatial variability over a relevant and specified scale, with the uncertainty included in this description. Different alternative descriptions may be required. After the individual discipline modelling and uncertainty assessment a phase of overall confidence evaluation follows. Relevant parts of the different modelling teams assess the suggested uncertainties and evaluate the feedback. These discussions should assess overall confidence by, checking that all relevant data are used, checking that information in past model versions is considered, checking that the different kinds of uncertainty are addressed, checking if suggested alternatives make sense and if there is potential for additional alternatives, and by discussing, if appropriate, how additional measurements (i.e. more data) would affect confidence. The findings as well as the modelling results are to be documented in a Site Description

  3. Operational Strategies for Low-Level Radioactive Waste Disposal Site in Egypt - 13513

    International Nuclear Information System (INIS)

    Mohamed, Yasser T.

    2013-01-01

    The ultimate aims of treatment and conditioning is to prepare waste for disposal by ensuring that the waste will meet the waste acceptance criteria of a disposal facility. Hence the purpose of low-level waste disposal is to isolate the waste from both people and the environment. The radioactive particles in low-level waste emit the same types of radiation that everyone receives from nature. Most low-level waste fades away to natural background levels of radioactivity in months or years. Virtually all of it diminishes to natural levels in less than 300 years. In Egypt, The Hot Laboratories and Waste Management Center has been established since 1983, as a waste management facility for LLW and ILW and the disposal site licensed for preoperational in 2005. The site accepts the low level waste generated on site and off site and unwanted radioactive sealed sources with half-life less than 30 years for disposal and all types of sources for interim storage prior to the final disposal. Operational requirements at the low-level (LLRW) disposal site are listed in the National Center for Nuclear Safety and Radiation Control NCNSRC guidelines. Additional procedures are listed in the Low-Level Radioactive Waste Disposal Facility Standards Manual. The following describes the current operations at the LLRW disposal site. (authors)

  4. Operational test report for LERF Basin 242AL-44 integrity test

    International Nuclear Information System (INIS)

    Galioto, T.M.

    1994-01-01

    This operational test report documents the results of LERF operational testing per operational test procedure (OTP) TFPE-WP-0231, ''LERF Basin Integrity Testing.'' The primary purpose of the OTP was to resolve test exceptions generated as a result of TFPE-WP-0184. The TOP was prepared and performed in accordance with WHC-SD-534-OTP-002, ''Operational Test Plan for the 242-A Evaporator Upgrades and the Liquid Effluent Retention Facility.'' WHC-S-086, ''Specification for Operational Testing of the Liquid Effluent Retention Facility, Basin Integrity Testing,'' identified the test requirements and acceptance criteria. The completed, signed-off test procedure is contained in Appendix A. The test log is contained in Appendix B. Section 2.1 describes all the test exceptions written during performance of the Operational Test Procedure. The test revisions generated during the testing are discussed in Section 2.2. The dispositioned test exception forms are contained in Appendix C

  5. Safe genetic modification of cardiac stem cells using a site-specific integration technique.

    Science.gov (United States)

    Lan, Feng; Liu, Junwei; Narsinh, Kazim H; Hu, Shijun; Han, Leng; Lee, Andrew S; Karow, Marisa; Nguyen, Patricia K; Nag, Divya; Calos, Michele P; Robbins, Robert C; Wu, Joseph C

    2012-09-11

    Human cardiac progenitor cells (hCPCs) are a promising cell source for regenerative repair after myocardial infarction. Exploitation of their full therapeutic potential may require stable genetic modification of the cells ex vivo. Safe genetic engineering of stem cells, using facile methods for site-specific integration of transgenes into known genomic contexts, would significantly enhance the overall safety and efficacy of cellular therapy in a variety of clinical contexts. We used the phiC31 site-specific recombinase to achieve targeted integration of a triple fusion reporter gene into a known chromosomal context in hCPCs and human endothelial cells. Stable expression of the reporter gene from its unique chromosomal integration site resulted in no discernible genomic instability or adverse changes in cell phenotype. Namely, phiC31-modified hCPCs were unchanged in their differentiation propensity, cellular proliferative rate, and global gene expression profile when compared with unaltered control hCPCs. Expression of the triple fusion reporter gene enabled multimodal assessment of cell fate in vitro and in vivo using fluorescence microscopy, bioluminescence imaging, and positron emission tomography. Intramyocardial transplantation of genetically modified hCPCs resulted in significant improvement in myocardial function 2 weeks after cell delivery, as assessed by echocardiography (P=0.002) and MRI (P=0.001). We also demonstrated the feasibility and therapeutic efficacy of genetically modifying differentiated human endothelial cells, which enhanced hind limb perfusion (Pmodification system is a safe, efficient tool to enable site-specific integration of reporter transgenes in progenitor and differentiated cell types.

  6. On p dependent boundedness of singular integral operators

    Czech Academy of Sciences Publication Activity Database

    Honzík, Petr

    2011-01-01

    Roč. 267, 3-4 (2011), s. 931-937 ISSN 0025-5874 Institutional research plan: CEZ:AV0Z10190503 Keywords : singular integral operators Subject RIV: BA - General Mathematics Impact factor: 0.749, year: 2011 http://www.springerlink.com/content/k507g30163351250/

  7. Analysis and interpretation of geophysical surveys in archaeological sites employing different integrated approach.

    Science.gov (United States)

    Piro, Salvatore; Papale, Enrico; Kucukdemirci, Melda; Zamuner, Daniela

    2017-04-01

    Non-destructive ground surface geophysical prospecting methods are frequently used for the investigation of archaeological sites, where a detailed physical and geometrical reconstructions of hidden volumes is required prior to any excavation work. All methods measure the variations of single physical parameters, therefore if these are used singularly, they could not permit a complete location and characterization of anomalous bodies. The probability of a successful result rapidly increases if a multhimethodological approach is adopted, according to the logic of objective complementarity of information and of global convergence toward a high quality multiparametric imaging of the buried structures. The representation of the static configuration of the bodies in the subsoil and of the space-time evolution of the interaction processes between targets and hosting materials have to be actually considered fundamental elements of primary knowledge in archaeological prospecting. The main effort in geophysical prospecting for archaeology is therefore the integration of different, absolutely non-invasive techniques, especially if managed in view of a ultra-high resolution three-dimensional (3D) tomographic representation mode. Following the above outlined approach, we have integrated geophysical methods which measure the variations of potential field (gradiometric methods) with active methods which measure the variations of physical properties due to the body's geometry and volume (GPR and ERT). In this work, the results obtained during the surveys of three archaeological sites, employing Ground Penetrating Radar (GPR), Electrical Resistivity Tomography (ERT) and Fluxgate Differential Magnetic (FDM) to obtain precise and detailed maps of subsurface bodies, are presented and discussed. The first site, situated in a suburban area between Itri and Fondi, in the Aurunci Natural Regional Park (Central Italy), is characterized by the presence of remains of past human activity

  8. Remedial investigation for the 200-BP-1 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    Buckmaster, M.A.

    1991-01-01

    The Hanford Site, Richland, Washington, contains over 1500 identified waste sites that will be characterized and remediated over the next 30 years. In support of the ''Hanford Federal Facility Agreement and Consent Order,'' the US Department of Energy has initiated a remedial investigation/feasibility study (RI/FS) at the 200-BP-1 operable unit. The 200-BP-1 RI is the first Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) investigation on the Hanford Site that involves drilling into highly radioactive and chemically contaminated soils. The initial phase of the site characterization is oriented toward determining the nature and extent of any contamination present in the vicinity of the 200-BP-1 operable unit. The major focus of the Phase I RI is the drilling and sampling of 10 inactive waste disposal units which received low level radioactive liquid waste

  9. The fuzzy TOPSIS and generalized Choquet fuzzy integral algorithm for nuclear power plant site selection - a case study from Turkey

    International Nuclear Information System (INIS)

    Kurt, Ünal

    2014-01-01

    The location selection for nuclear power plant (NPP) is a strategic decision, which has significant impact on the economic operation of the plant and sustainable development of the region. This paper proposes fuzzy TOPSIS and generalized Choquet fuzzy integral algorithm for evaluation and selection of optimal locations for NPP in Turkey. Many sub-criteria such as geological, social, touristic, transportation abilities, cooling water capacity and nearest to consumptions markets are taken into account. Among the evaluated locations, according to generalized Choquet fuzzy integral method, Inceburun–Sinop was selected as a study site due to its highest performance and meeting most of the investigated criteria. The Inceburun-Sinop is selected by generalized Choquet fuzzy integral and fuzzy TOPSIS Iğneada–Kırklareli took place in the first turn. The Mersin–Akkuyu is not selected in both methods. (author)

  10. Integration of Weather Data into Airspace and Traffic Operations Simulation (ATOS) for Trajectory- Based Operations Research

    Science.gov (United States)

    Peters, Mark; Boisvert, Ben; Escala, Diego

    2009-01-01

    Explicit integration of aviation weather forecasts with the National Airspace System (NAS) structure is needed to improve the development and execution of operationally effective weather impact mitigation plans and has become increasingly important due to NAS congestion and associated increases in delay. This article considers several contemporary weather-air traffic management (ATM) integration applications: the use of probabilistic forecasts of visibility at San Francisco, the Route Availability Planning Tool to facilitate departures from the New York airports during thunderstorms, the estimation of en route capacity in convective weather, and the application of mixed-integer optimization techniques to air traffic management when the en route and terminal capacities are varying with time because of convective weather impacts. Our operational experience at San Francisco and New York coupled with very promising initial results of traffic flow optimizations suggests that weather-ATM integrated systems warrant significant research and development investment. However, they will need to be refined through rapid prototyping at facilities with supportive operational users We have discussed key elements of an emerging aviation weather research area: the explicit integration of aviation weather forecasts with NAS structure to improve the effectiveness and timeliness of weather impact mitigation plans. Our insights are based on operational experiences with Lincoln Laboratory-developed integrated weather sensing and processing systems, and derivative early prototypes of explicit ATM decision support tools such as the RAPT in New York City. The technical components of this effort involve improving meteorological forecast skill, tailoring the forecast outputs to the problem of estimating airspace impacts, developing models to quantify airspace impacts, and prototyping automated tools that assist in the development of objective broad-area ATM strategies, given probabilistic

  11. Operational constraints and hydrologic variability limit hydropower in supporting wind integration

    International Nuclear Information System (INIS)

    Fernandez, Alisha R; Blumsack, Seth A; Reed, Patrick M

    2013-01-01

    Climate change mitigation will require rapid adoption of low-carbon energy resources. The integration of large-scale wind energy in the United States (US) will require controllable assets to balance the variability of wind energy production. Previous work has identified hydropower as an advantageous asset, due to its flexibility and low-carbon emissions production. While many dams currently provide energy and environmental services in the US and globally, we find that multi-use hydropower facilities would face significant policy conflicts if asked to store and release water to accommodate wind integration. Specifically, we develop a model simulating hydroelectric operational decisions when the electric facility is able to provide wind integration services through a mechanism that we term ‘flex reserves’. We use Kerr Dam in North Carolina as a case study, simulating operations under two alternative reservoir policies, one reflecting current policies and the other regulating flow levels to promote downstream ecosystem conservation. Even under perfect information and significant pricing incentives, Kerr Dam faces operational conflicts when providing any substantial levels of flex reserves while also maintaining releases consistent with other river management requirements. These operational conflicts are severely exacerbated during periods of drought. Increase of payments for flex reserves does not resolve these operational and policy conflicts. (letter)

  12. Meta-Analysis of DNA Tumor-Viral Integration Site Selection Indicates a Role for Repeats, Gene Expression and Epigenetics

    Directory of Open Access Journals (Sweden)

    Janet M. Doolittle-Hall

    2015-11-01

    Full Text Available Oncoviruses cause tremendous global cancer burden. For several DNA tumor viruses, human genome integration is consistently associated with cancer development. However, genomic features associated with tumor viral integration are poorly understood. We sought to define genomic determinants for 1897 loci prone to hosting human papillomavirus (HPV, hepatitis B virus (HBV or Merkel cell polyomavirus (MCPyV. These were compared to HIV, whose enzyme-mediated integration is well understood. A comprehensive catalog of integration sites was constructed from the literature and experimentally-determined HPV integration sites. Features were scored in eight categories (genes, expression, open chromatin, histone modifications, methylation, protein binding, chromatin segmentation and repeats and compared to random loci. Random forest models determined loci classification and feature selection. HPV and HBV integrants were not fragile site associated. MCPyV preferred integration near sensory perception genes. Unique signatures of integration-associated predictive genomic features were detected. Importantly, repeats, actively-transcribed regions and histone modifications were common tumor viral integration signatures.

  13. Wind power integration connection and system operational aspects

    CERN Document Server

    Fox, Brendan

    2014-01-01

    Wind Power Integration provides a wide-ranging discussion on all major aspects of wind power integration into electricity supply systems. This second edition has been fully revised and updated to take account of the significant growth in wind power deployment in the past few years. New discussions have been added to describe developments in wind turbine generator technology and control, the network integration of wind power, innovative ways to integrate wind power when its generation potential exceeds 50% of demand, case studies on how forecasting errors have affected system operation, and an update on how the wind energy sector has fared in the marketplace. Topics covered include: the development of wind power technology and its world-wide deployment; wind power technology and the interaction of various wind turbine generator types with the utility network; and wind power forecasting and the challenges faced by wind energy in modern electricity markets.

  14. Assessment of the Nevada Test Site as a Site for Distributed Resource Testing and Project Plan: March 2002

    Energy Technology Data Exchange (ETDEWEB)

    Horgan, S.; Iannucci, J.; Whitaker, C.; Cibulka, L.; Erdman, W.

    2002-05-01

    The objective of this project was to evaluate the Nevada Test Site (NTS) as a location for performing dedicated, in-depth testing of distributed resources (DR) integrated with the electric distribution system. In this large scale testing, it is desired to operate multiple DRs and loads in an actual operating environment, in a series of controlled tests to concentrate on issues of interest to the DR community. This report includes an inventory of existing facilities at NTS, an assessment of site attributes in relation to DR testing requirements, and an evaluation of the feasibility and cost of upgrades to the site that would make it a fully qualified DR testing facility.

  15. Application for a Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site Area 5 Asbestiform Low-Level Solid Waste Disposal Site

    International Nuclear Information System (INIS)

    2010-01-01

    The NTS solid waste disposal sites must be permitted by the state of Nevada Solid Waste Management Authority (SWMA). The SWMA for the NTS is the Nevada Division of Environmental Protection, Bureau of Federal Facilities (NDEP/BFF). The U.S. Department of Energy's National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as land manager (owner), and National Security Technologies (NSTec), as operator, will store, collect, process, and dispose all solid waste by means that do not create a health hazard, a public nuisance, or cause impairment of the environment. NTS disposal sites will not be included in the Nye County Solid Waste Management Plan. The NTS is located approximately 105 kilometers (km) (65 miles (mi)) northwest of Las Vegas, Nevada (Figure 1). The U.S. Department of Energy (DOE) is the federal lands management authority for the NTS, and NSTec is the Management and Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS has signs posted along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The Area 5 RWMS is the location of the permitted facility for the Solid Waste Disposal Site (SWDS). The Area 5 RWMS is located near the eastern edge of the NTS (Figure 2), approximately 26 km (16 mi) north of Mercury, Nevada. The Area 5 RWMS is used for the disposal of low-level waste (LLW) and mixed low-level waste. Many areas surrounding the RWMS have been used in conducting nuclear tests. A Notice of Intent to operate the disposal site as a Class III site was submitted to the state of Nevada on January 28, 1994, and was acknowledged as being received in a letter to the NNSA/NSO on August 30, 1994. Interim approval to operate a Class III SWDS for regulated asbestiform low-level waste (ALLW) was authorized on August 12, 1996 (in letter from Paul Liebendorfer to Runore Wycoff), with operations to be conducted in accordance with the ''Management Plan

  16. Denver Radium Site -- Operable Unit I closeout report for the US Environmental Protection Agency

    International Nuclear Information System (INIS)

    1992-08-01

    The Denver Radium Site consists of properties in the Denver, Colorado, area having radioactive contamination left from radium processing in the early 1900s. The properties are divided into 11 gaps or operable units to facilitate remedial action of the Site. Operable Unit I is an 8-acre block bounded by Quivas Street to the east, Shoshone Street to the west, West 12th Avenue to the south, and West 13th Avenue to the north. The primary focus of interest concerning investigations of radiological contamination was a radium, vanadium, and uranium processing facility at 1201 Quivas Street owned by the Pittsburgh Radium Company (PRC) from 1925 until 1926. The Radium Ores Company, which was associated with PRC, operated the facility until 1927. A Remedial investigation (RI) of Operable Unit I was prepared by Jacobs Engineering Group and CH 2 M Hill on behalf of EPA in April 1986. The draft Feasibility Study (FS), prepared by Jacobs Engineering Group and CH 2 M Hill, was issued in July 1987 (the final FS is the Community Relations Responsiveness Summary with an errata to the draft, issued September 1987). The RI focused on radium uranium processing residues discarded in the early 1900s. These residues contained uranium, radium, and thorium. EPA s Community Relations Plan involved the community in the decision-making process relating to the remedy to be implemented at Operable Unit X, and promoted communications among interested parties throughout the course of the project. The remedial action alternative preferred by EPA for Operable Unit I was Off-Site Permanent Disposal. Because a permanent disposal facility was not available at the time the Record of Decision was issued in September 1987, EPA selected the On-Site Temporary Containment (capping) with the Off-Site Permanent Disposal alternative

  17. The Linkage of Joint Operational Fires, Information Operations and the Army: Does the Army Have Effective Feedback Mechanisms that Integrate Operational Fires (Physical Destruction) and Information Operations?

    National Research Council Canada - National Science Library

    Mills, Charles

    2004-01-01

    The information revolution seems to hold a lot of promise to the U.S. economy and the U.S. military, but rigid bureaucratic hierarchies make it extremely difficult for effective integration of operational fires and information operations...

  18. Singularities of affine fibrations in the regularity theory of Fourier integral operators

    International Nuclear Information System (INIS)

    Ruzhansky, M V

    2000-01-01

    We consider regularity properties of Fourier integral operators in various function spaces. The most interesting case is the L p spaces, for which survey of recent results is given. For example, sharp orders are known for operators satisfying the so-called smooth factorization condition. Here this condition is analyzed in both real and complex settings. In the letter case, conditions for the continuity of Fourier integral operators are related to singularities of affine fibrations in C n (or subsets of C n ) specified by the kernels of Jacobi matrices of holomorphic maps. Singularities of such fibrations are analyzed in this paper in the general case. In particular, it is shown that if the dimension n or the rank of the Jacobi matrix is small, then all singularities of an affine fibration are removable. The fibration associated with a Fourier integral operator is given by the kernels of the Hessian of the phase function of the operator. On the basis of an analysis of singularities for operators commuting with translations we show in a number of cases that the factorization condition is satisfied, which leads to L p estimates for operators. In other cases, examples are given in which the factorization condition fails. The results are applied to deriving L p estimates for solutions of the Cauchy problem for hyperbolic partial differential operators

  19. Weighted estimates for the averaging integral operator

    Czech Academy of Sciences Publication Activity Database

    Opic, Bohumír; Rákosník, Jiří

    2010-01-01

    Roč. 61, č. 3 (2010), s. 253-262 ISSN 0010-0757 R&D Projects: GA ČR GA201/05/2033; GA ČR GA201/08/0383 Institutional research plan: CEZ:AV0Z10190503 Keywords : averaging integral operator * weighted Lebesgue spaces * weights Subject RIV: BA - General Mathematics Impact factor: 0.474, year: 2010 http://link.springer.com/article/10.1007%2FBF03191231

  20. Integrated training support system for PWR operator training simulator

    International Nuclear Information System (INIS)

    Sakaguchi, Junichi; Komatsu, Yasuki

    1999-01-01

    The importance of operator training using operator training simulator has been recognized intensively. Since 1986, we have been developing and providing many PWR simulators in Japan. We also have developed some training support systems connected with the simulator and the integrated training support system to improve training effect and to reduce instructor's workload. This paper describes the concept and the effect of the integrated training support system and of the following sub-systems. We have PES (Performance Enhancement System) that evaluates training performance automatically by analyzing many plant parameters and operation data. It can reduce the deviation of training performance evaluation between instructors. PEL (Parameter and Event data Logging system), that is the subset of PES, has some data-logging functions. And we also have TPES (Team Performance Enhancement System) that is used aiming to improve trainees' ability for communication between operators. Trainee can have conversation with virtual trainees that TPES plays automatically. After that, TPES automatically display some advice to be improved. RVD (Reactor coolant system Visual Display) displays the distributed hydraulic-thermal condition of the reactor coolant system in real-time graphically. It can make trainees understand the inside plant condition in more detail. These sub-systems have been used in a training center and have contributed the improvement of operator training and have gained in popularity. (author)

  1. Overview of Low-Level Waste Disposal Operations at the Nevada Test Site

    International Nuclear Information System (INIS)

    2007-01-01

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Environmental Management Program is charged with the responsibility to carry out the disposal of on-site and off-site generated low-level radioactive waste at the Nevada Test Site. Core elements of this mission are ensuring that disposal take place in a manner that is safe and cost-effective while protecting workers, the public, and the environment. This paper focuses on giving an overview of the Nevada Test Site facilities regarding currant design of disposal. In addition, technical attributes of the facilities established through the site characterization process will be further described. An update on current waste disposal volumes and capabilities will also be provided. This discussion leads to anticipated volume projections and disposal site requirements as the Nevada Test Site disposal operations look towards the future

  2. Integrated Patient Education on U.S. Hospital Web Sites.

    Science.gov (United States)

    Huang, Edgar; Wu, Kerong; Edwards, Kelsey

    2016-01-01

    Based on a census of the 2015 Most Wired Hospitals, this content analysis aimed to find out how patient education has been integrated on these best IT hospitals' Web sites to serve the purposes of marketing and meeting online visitors' needs. This study will help hospitals to understand where the weaknesses are in their interactive patient education implementation and come up with a smart integration strategy. The study found that 70% of these hospitals had adopted interactive patient education contents, 76.6% of such contents were from a third-party developer, and only 20% of the hospitals linked their patient education contents to one or more of the hospital's resources while 26% cross-references such contents. The authors concluded that more hospitals should take advantage of modern information communication technology to cross-reference their patient education contents and to integrate such contents into their overall online marketing strategy to benefit patients and themselves.

  3. HUG sets up an emergency operations centre on the CERN site

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Discussions between CERN and the Hôpitaux universitaires de Genève (HUG), under the aegis of the Swiss authorities, have resulted in the setting-up of an emergency operations centre on the CERN site. This will be the operations base for an emergency doctor, a medical emergency vehicle and a driver. Located on the Swiss part of the Meyrin site, close to Building 57, it will be inaugurated on 20 May.   SMUR team based at CERN. CERN’s medical staff and fire-fighters dispense first aid but in medical emergencies they are obliged to call on outside services to treat and transfer patients to hospital. In the Canton of Geneva, this service is provided by HUG via the 144 emergency line. But HUG is based on the eastern side of Geneva, a long way from CERN, and response times can be substantial. In order to improve the safety of the growing number of people on the site, CERN asked Switzerland, as one of its Host States, to help it reduce the medical emergency response t...

  4. Nuclear Material Processing at the Savannah River Site

    International Nuclear Information System (INIS)

    Severynse, T.F.

    1998-07-01

    Plutonium production for national defense began at Savannah River in the mid-1950s, following construction of production reactors and separations facilities. Following the successful completion of its production mission, the site's nuclear material processing facilities continue to operate to perform stabilization of excess materials and potentially support the disposition of these materials. A number of restoration and productivity improvement projects implemented in the 1980s, totaling nearly a billion dollars, have resulted in these facilities representing the most modern and only remaining operating large-scale processing facilities in the DOE Complex. Together with the Site's extensive nuclear infrastructure, and integrated waste management system, SRS is the only DOE site with the capability and mission of ongoing processing operations

  5. Comprehensive Solutions for Integration of Solar Resources into Grid Operations

    Energy Technology Data Exchange (ETDEWEB)

    Pennock, Kenneth [AWS Truepower, LLC, Albany, NY (United States); Makarov, Yuri V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rajagopal, Sankaran [Siemens Energy, Erlangen (Germany); Loutan, Clyde [California Independent System Operator; Etingov, Pavel V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Miller, Laurie E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lu, Bo [Siemens Energy, Erlangen (Germany); Mansingh, Ashmin [Siemens Energy, Erlangen (Germany); Zack, John [MESO, Inc., Raleigh, NC (United States); Sherick, Robert [Southern California Edison, Rosemead, CA (United States); Romo, Abraham [Southern California Edison; Habibi-Ashrafi, Farrokh [Southern California Edison; Johnson, Raymond [Southern California Edison

    2016-01-14

    The need for proactive closed-loop integration of uncertainty information into system operations and probability-based controls is widely recognized, but rarely implemented in system operations. Proactive integration for this project means that the information concerning expected uncertainty ranges for net load and balancing requirements, including required balancing capacity, ramping and ramp duration characteristics, will be fed back into the generation commitment and dispatch algorithms to modify their performance so that potential shortages of these characteristics can be prevented. This basic, yet important, premise is the motivating factor for this project. The achieved project goal is to demonstrate the benefit of such a system. The project quantifies future uncertainties, predicts additional system balancing needs including the prediction intervals for capacity and ramping requirements of future dispatch intervals, evaluates the impacts of uncertainties on transmission including the risk of overloads and voltage problems, and explores opportunities for intra-hour generation adjustments helping to provide more flexibility for system operators. The resulting benefits culminate in more reliable grid operation in the face of increased system uncertainty and variability caused by solar power. The project identifies that solar power does not require special separate penetration level restrictions or penalization for its intermittency. Ultimately, the collective consideration of all sources of intermittency distributed over a wide area unified with the comprehensive evaluation of various elements of balancing process, i.e. capacity, ramping, and energy requirements, help system operators more robustly and effectively balance generation against load and interchange. This project showed that doing so can facilitate more solar and other renewable resources on the grid without compromising reliability and control performance. Efforts during the project included

  6. Development of an integrated economic decision-support tool for the remediation of contaminated sites. Overview note

    International Nuclear Information System (INIS)

    Samson, R.; Bage, G.

    2004-05-01

    , and costs of treatment according to the most current ranges obtained from the literature. For bio-venting and bio-pile treatment, which are used in the simulations described in this report, a list of equipment requirements, established according to the requirements of the virtual site, accompanies the technology files. Rather than employing economic databases specific to each technology as an integral part of the software, the software makes use of a system of generalized databases applicable to all technologies and specialized databases for various remedial operations (e.g., laboratory analyses, air extraction system). The databases specific to a given technology for a given site will be created from the system of generalized and specialized databases for each simulation, as required. This permits a high degree of flexibility in the economic evaluation of each technology, and facilitates updating (a single modification is sufficient for an element that may be used by several technologies). Twelve simulations have been realized for the remediation of a virtual site contaminated by diesel. Each simulation is constrained by a time limit for remediation and/or by a maximum benefit associated with the remediated site. The complexity of some optimal remediation strategies underlines the need for site managers to utilize a tool such as SITE VII. Finally, having established the foundations of the software, this report presents a series of recommendations for future work for completing the design of SITE VII, in order to make it complete, functional, and equipped with a user-friendly interface. (authors)

  7. Site scientific mission plan for the southern great plains CART site January-June 2000.; TOPICAL

    International Nuclear Information System (INIS)

    Peppler, R. A.; Sisterson, D. L.; Lamb, P.

    2001-01-01

    The Southern Great Plains (SGP) Cloud and Radiation Testbed (CART) site was designed to help satisfy the data needs of the Atmospheric Radiation Measurement (ARM) Program Science Team. This Site Scientific Mission Plan defines the scientific priorities for site activities during the six months beginning on January 1, 2000, and looks forward in less detail to subsequent six-month periods. The primary purpose of this document is to provide scientific guidance for the development of plans for site operations. It also provides information on current plans to the ARM functional teams (Management Team, Data and Science Integration Team[DSIT], Operations Team, and Instrument Team[IT]) and serves to disseminate the plans more generally within the ARM Program and among the members of the Science Team. This document includes a description of the operational status of the site and the primary site activities envisioned, together with information concerning approved and proposed intensive observation periods (IOPs). The primary users of this document are the site operator, the site program manager, the Site Scientist Team (SST), the Science Team through the ARM Program science director, the ARM Program Experiment Center, and the aforementioned ARM Program functional teams. This plan is a living document that is updated and reissued every six months as the observational facilities are developed, tested, and augmented and as priorities are adjusted in response to developments in scientific planning and understanding. With this issue, many aspects of earlier Site Scientific Mission Plan reports have been moved to ARM sites on the World Wide Web. This report and all previous reports are available on the SGP CART web site

  8. Title V Operating Permit: XTO Energy, Inc. - River Bend Dehydration Site

    Science.gov (United States)

    Initial Title V Operating Permit (Permit Number: V-UO-000026-2011.00) and the Administrative Permit Record for the XTO Energy, Inc., River Bend Dehydration Site, located on the Uintah and Ouray Indian Reservation.

  9. Operational test report, integrated system test (ventilation upgrade)

    International Nuclear Information System (INIS)

    HARTY, W.M.

    1999-01-01

    Operational Final Test Report for Integrated Systems, Project W-030 (Phase 2 test, RECIRC and HIGH-HEAT Modes). Project W-030 provides a ventilation upgrade for the four Aging Waste Facility tanks, including upgraded vapor space cooling and filtered venting of tanks AY101, AY102, AZ101, AZ102

  10. Operational test report integrated system test (ventilation upgrade)

    Energy Technology Data Exchange (ETDEWEB)

    HARTY, W.M.

    1999-10-05

    Operational Final Test Report for Integrated Systems, Project W-030 (Phase 2 test, RECIRC and HIGH-HEAT Modes). Project W-030 provides a ventilation upgrade for the four Aging Waste Facility tanks, including upgraded vapor space cooling and filtered venting of tanks AY101, Ay102, AZ101, AZ102.

  11. Mercury Deposition Network Site Operator Training for the System Blank and Blind Audit Programs

    Science.gov (United States)

    Wetherbee, Gregory A.; Lehmann, Christopher M.B.

    2008-01-01

    The U.S. Geological Survey operates the external quality assurance project for the National Atmospheric Deposition Program/Mercury Deposition Network. The project includes the system blank and blind audit programs for assessment of total mercury concentration data quality for wet-deposition samples. This presentation was prepared to train new site operators and to refresh experienced site operators to successfully process and submit system blank and blind audit samples for chemical analysis. Analytical results are used to estimate chemical stability and contamination levels of National Atmospheric Deposition Program/Mercury Deposition Network samples and to evaluate laboratory variability and bias.

  12. Integration and consistency testing of groundwater flow models with hydro-geochemistry in site investigations in Finland

    International Nuclear Information System (INIS)

    Pitkaenen, P.; Loefman, J.; Korkealaakso, J.; Koskinen, L.; Ruotsalainen, P.; Hautojaervi, A.; Aeikaes, T.

    1999-01-01

    In the assessment of the suitability and safety of a geological repository for radioactive waste the understanding of the fluid flow at a site is essential. In order to build confidence in the assessment of the hydrogeological performance of a site in various conditions, integration of hydrological and hydrogeochemical methods and studies provides the primary method for investigating the evolution that has taken place in the past, and for predicting future conditions at the potential disposal site. A systematic geochemical sampling campaign was started since the beginning of 1990's in the Finnish site investigation programme. This enabled the initiating of integration and evaluation of site scale hydrogeochemical and groundwater flow models. Hydrogeochemical information has been used to screen relevant external processes and variables for definition of the initial and boundary conditions in hydrological simulations. The results obtained from interpretation and modelling hydrogeochemical evolution have been employed in testing the hydrogeochemical consistency of conceptual flow models. Integration and testing of flow models with hydrogeochemical information are considered to improve significantly the hydrogeological understanding of a site and increases confidence in conceptual hydrogeological models. (author)

  13. Prototype development and demonstration for integrated dynamic transit operations.

    Science.gov (United States)

    2016-01-01

    This document serves as the Final Report specific to the Integrated Dynamic Transit Operations (IDTO) Prototype Development and Deployment Project, hereafter referred to as IDTO Prototype Deployment or IDTO PD project. This project was performed unde...

  14. Interim remedial measures proposed plan for the 200-ZP-1 Operable Unit, Hanford Site, Washington

    International Nuclear Information System (INIS)

    Parker, D.L.

    1993-12-01

    The purpose of this interim remedial measures (IRM) proposed plan is to present and solicit public comments on the IRM planned for the 200-ZP-1 Operable Unit at the Hanford Site in Washington state. The 200-ZP-1 is one of two operable units that envelop the groundwater beneath the 200 West Area of the Hanford Site

  15. Integration Site and Clonal Expansion in Human Chronic Retroviral Infection and Gene Therapy

    Science.gov (United States)

    Niederer, Heather A.; Bangham, Charles R. M.

    2014-01-01

    Retroviral vectors have been successfully used therapeutically to restore expression of genes in a range of single-gene diseases, including several primary immunodeficiency disorders. Although clinical trials have shown remarkable results, there have also been a number of severe adverse events involving malignant outgrowth of a transformed clonal population. This clonal expansion is influenced by the integration site profile of the viral integrase, the transgene expressed, and the effect of the viral promoters on the neighbouring host genome. Infection with the pathogenic human retrovirus HTLV-1 also causes clonal expansion of cells containing an integrated HTLV-1 provirus. Although the majority of HTLV-1-infected people remain asymptomatic, up to 5% develop an aggressive T cell malignancy. In this review we discuss recent findings on the role of the genomic integration site in determining the clonality and the potential for malignant transformation of cells carrying integrated HTLV-1 or gene therapy vectors, and how these results have contributed to the understanding of HTLV-1 pathogenesis and to improvements in gene therapy vector safety. PMID:25365582

  16. Electric and Hybrid Vehicle Program, Site Operator Program. Quarterly progress report, January--March 1996

    Energy Technology Data Exchange (ETDEWEB)

    Francfort, J.E. [Lockheed Martin Idaho Technologies Co., Idaho Falls, ID (United States); Bassett, R.R. [Sandia National Labs., Albuquerque, NM (United States); Briasco, S. [Los Angeles City Dept. of Water and Power, CA (United States)] [and others

    1996-08-01

    Goals of the site operator program include field evaluation of electric vehicles (EVs) in real-world applications and environments, advancement of electric vehicle technologies, development of infrastructure elements necessary to support significant EV use, and increasing the awareness and acceptance of EVs by the public. The site operator program currently consists of 11 participants under contract and two other organizations with data-sharing agreements with the program. The participants (electric utilities, academic institutions, Federal agencies) are geographically dispersed within US and their vehicles see a broad spectrum of service conditions. Current EV inventories of the site operators exceeds 250 vehicles. Several national organizations have joined DOE to further the introduction and awareness of EVs, including: (1) EVAmerica (a utility program) and DOE conduct performance and evaluation tests to support market development for EVs; (2) DOE, DOT, the Electric Transportation Coalition, and the Electric Vehicle Association of the Americas are conducting a series of workshops to encourage urban groups in Clean Cities (a DOE program) to initiate the policies and infrastructure development necessary to support large-scale demonstrations, and ultimately the mass market use, of EVs. Current focus of the program is collection and dissemination of EV operations and performance data to aid in the evaluation of real- world EV use. This report contains several sections with vehicle evaluation as a focus: EV testing results, energy economics of EVs, and site operators activities.

  17. Integrating truck arrival management into tactical operation planning at container terminals

    DEFF Research Database (Denmark)

    Yang, Zhong-Zhen; Chen, Gang; Song, Dong-Ping

    2013-01-01

    Truck arrival management (TAM) has been recognized as an effective solution to alleviate the gate congestion at container terminals. To further utilize TAM in improving the overall terminal performance, this study integrates TAM with the other terminal operations at a tactical level. An integrated...

  18. Integrated real-time information to use in commercial, logistics and operational activities provide by the national control center operation of Transpetro

    Energy Technology Data Exchange (ETDEWEB)

    Aniceto, Hello A. R. [National Control Center Operation Transpetro, Rio de Janeiro, (Brazil)

    2010-07-01

    TRANSPETRO needed real time computational tools to manage its commercial, logistics and operational activities more efficiently. TRANSPETRO's National Control Center Operation developed an information site that provides information in real time on the process plans involved in each operation, using a Plant Information Management System (PIMS). SCADA systems were introduced during 2009 and 2010. This paper reports on the global introduction of the site and its basic architecture. Every screen displays the overall data in real time on movement in volume in pipeline operated by TRANSPETRO. The products transported are tracked for each infrastructure and are shown on dynamic geographic maps. Applications have been developed to improve the quality of information available to customers. It was found that the development of this site using PIMS technology brought gains in support to decision-making at the strategic and tactical levels for TRANSPETRO.

  19. A dynamic multimedia fuzzy-stochastic integrated environmental risk assessment approach for contaminated sites management

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Yan; Wen, Jing-ya; Li, Xiao-li; Wang, Da-zhou; Li, Yu, E-mail: liyuxx8@hotmail.com

    2013-10-15

    Highlights: • Using interval mathematics to describe spatial and temporal variability and parameter uncertainty. • Using fuzzy theory to quantify variability of environmental guideline values. • Using probabilistic approach to integrate interval concentrations and fuzzy environmental guideline. • Establishment of dynamic multimedia environmental integrated risk assessment framework. -- Abstract: A dynamic multimedia fuzzy-stochastic integrated environmental risk assessment approach was developed for contaminated sites management. The contaminant concentrations were simulated by a validated interval dynamic multimedia fugacity model, and different guideline values for the same contaminant were represented as a fuzzy environmental guideline. Then, the probability of violating environmental guideline (Pv) can be determined by comparison between the modeled concentrations and the fuzzy environmental guideline, and the constructed relationship between the Pvs and environmental risk levels was used to assess the environmental risk level. The developed approach was applied to assess the integrated environmental risk at a case study site in China, simulated from 1985 to 2020. Four scenarios were analyzed, including “residential land” and “industrial land” environmental guidelines under “strict” and “loose” strictness. It was found that PAH concentrations will increase steadily over time, with soil found to be the dominant sink. Source emission in soil was the leading input and atmospheric sedimentation was the dominant transfer process. The integrated environmental risks primarily resulted from petroleum spills and coke ovens, while the soil environmental risks came from coal combustion. The developed approach offers an effective tool for quantifying variability and uncertainty in the dynamic multimedia integrated environmental risk assessment and the contaminated site management.

  20. A dynamic multimedia fuzzy-stochastic integrated environmental risk assessment approach for contaminated sites management

    International Nuclear Information System (INIS)

    Hu, Yan; Wen, Jing-ya; Li, Xiao-li; Wang, Da-zhou; Li, Yu

    2013-01-01

    Highlights: • Using interval mathematics to describe spatial and temporal variability and parameter uncertainty. • Using fuzzy theory to quantify variability of environmental guideline values. • Using probabilistic approach to integrate interval concentrations and fuzzy environmental guideline. • Establishment of dynamic multimedia environmental integrated risk assessment framework. -- Abstract: A dynamic multimedia fuzzy-stochastic integrated environmental risk assessment approach was developed for contaminated sites management. The contaminant concentrations were simulated by a validated interval dynamic multimedia fugacity model, and different guideline values for the same contaminant were represented as a fuzzy environmental guideline. Then, the probability of violating environmental guideline (Pv) can be determined by comparison between the modeled concentrations and the fuzzy environmental guideline, and the constructed relationship between the Pvs and environmental risk levels was used to assess the environmental risk level. The developed approach was applied to assess the integrated environmental risk at a case study site in China, simulated from 1985 to 2020. Four scenarios were analyzed, including “residential land” and “industrial land” environmental guidelines under “strict” and “loose” strictness. It was found that PAH concentrations will increase steadily over time, with soil found to be the dominant sink. Source emission in soil was the leading input and atmospheric sedimentation was the dominant transfer process. The integrated environmental risks primarily resulted from petroleum spills and coke ovens, while the soil environmental risks came from coal combustion. The developed approach offers an effective tool for quantifying variability and uncertainty in the dynamic multimedia integrated environmental risk assessment and the contaminated site management

  1. Space Station - An integrated approach to operational logistics support

    Science.gov (United States)

    Hosmer, G. J.

    1986-01-01

    Development of an efficient and cost effective operational logistics system for the Space Station will require logistics planning early in the program's design and development phase. This paper will focus on Integrated Logistics Support (ILS) Program techniques and their application to the Space Station program design, production and deployment phases to assure the development of an effective and cost efficient operational logistics system. The paper will provide the methodology and time-phased programmatic steps required to establish a Space Station ILS Program that will provide an operational logistics system based on planned Space Station program logistics support.

  2. Indigenous development of system integration for proton exchange membrane fuel cell operation

    International Nuclear Information System (INIS)

    Hussain, S.; Arshad, M.; Anjum, A.R.

    2011-01-01

    System integration was developed for fuel cell to control various parameters including voltage, current, power, temperature, pressure of gas (H/sub 2/), humidification, etc. The compact software has also been developed for monitoring different parameters of fuel cell system. System integrated was installed on fuel cell stack to manipulate these parameters. The compact software has been linked with the integrated system for visual monitoring of different parameters of fuel cell system during operation on PC. The installation of software and integrated system on fuel cell stack is the key achievement for the safe operation of fuel cell stack and for the provision of requisite power to any electric device for optimum performance. The compact software was developed for micro controller in KIEL. Control card and driver card are controlled by software-driven micro controller. A communication protocol was designed and developed. PC software has been developed to control and watch the values of all parameters of fuel cell such as voltage, current, power, temperature, pressure of hydrogen, pressure of oxygen, operational times and performance of the system on computer screen. (author)

  3. Regulatory requirements of the integrated technology demonstration program, Savannah River Site (U)

    International Nuclear Information System (INIS)

    Bergren, C.L.

    1992-01-01

    The integrated demonstration program at the Savannah River Site (SRS) involves demonstration, testing and evaluation of new characterization, monitoring, drilling and remediation technologies for soils and groundwater impacted by organic solvent contamination. The regulatory success of the demonstration program has developed as a result of open communications between the regulators and the technical teams involved. This open dialogue is an attempt to allow timely completion of applied environmental restoration demonstrations while meeting all applicable regulatory requirements. Simultaneous processing of multiple regulatory documents (satisfying RCRA, CERCLA, NEPA and various state regulations) has streamlined the overall permitting process. Public involvement is achieved as various regulatory documents are advertised for public comment consistent with the site's community relations plan. The SRS integrated demonstration has been permitted and endorsed by regulatory agencies, including the Environmental Protection Agency (EPA) and the South Carolina Department of Health and Environmental Control. EPA headquarters and regional offices are involved in DOE's integrated Demonstration Program. This relationship allows for rapid regulatory acceptance while reducing federal funding and time requirements. (author)

  4. Idaho National Laboratory Site Pollution Prevention Plan

    International Nuclear Information System (INIS)

    E. D. Sellers

    2007-01-01

    It is the policy of the Department of Energy (DOE) that pollution prevention and sustainable environmental stewardship will be integrated into DOE operations as a good business practice to reduce environmental hazards, protect environmental resources, avoid pollution control costs, and improve operational efficiency and mission sustainability. In furtherance of this policy, DOE established five strategic, performance-based Pollution Prevention (P2) and Sustainable Environmental Stewardship goals and included them as an attachment to DOE O 450.1, Environmental Protection Program. These goals and accompanying strategies are to be implemented by DOE sites through the integration of Pollution Prevention into each site's Environmental Management System (EMS). This document presents a P2 and Sustainability Program and corresponding plan pursuant to DOE Order 450.1 and DOE O 435.1, Radioactive Waste Management. This plan is also required by the state of Idaho, pursuant to the Resource Conservation and Recovery Act (RCRA) partial permit. The objective of this document is to describe the Idaho National Laboratory (INL) Site P2 and Sustainability Program. The purpose of the program is to decrease the environmental footprint of the INL Site while providing enhanced support of its mission. The success of the program is dependent on financial and management support. The signatures on the previous page indicate INL, ICP, and AMWTP Contractor management support and dedication to the program. P2 requirements have been integrated into working procedures to ensure an effective EMS as part of an Integrated Safety Management System (ISMS). This plan focuses on programmatic functions which include environmentally preferable procurement, sustainable design, P2 and Sustainability awareness, waste generation and reduction, source reduction and recycling, energy management, and pollution prevention opportunity assessments. The INL Site P2 and Sustainability Program is administratively

  5. Idaho National Laboratory Site Pollution Prevention Plan

    Energy Technology Data Exchange (ETDEWEB)

    E. D. Sellers

    2007-03-01

    It is the policy of the Department of Energy (DOE) that pollution prevention and sustainable environmental stewardship will be integrated into DOE operations as a good business practice to reduce environmental hazards, protect environmental resources, avoid pollution control costs, and improve operational efficiency and mission sustainability. In furtherance of this policy, DOE established five strategic, performance-based Pollution Prevention (P2) and Sustainable Environmental Stewardship goals and included them as an attachment to DOE O 450.1, Environmental Protection Program. These goals and accompanying strategies are to be implemented by DOE sites through the integration of Pollution Prevention into each site's Environmental Management System (EMS). This document presents a P2 and Sustainability Program and corresponding plan pursuant to DOE Order 450.1 and DOE O 435.1, Radioactive Waste Management. This plan is also required by the state of Idaho, pursuant to the Resource Conservation and Recovery Act (RCRA) partial permit. The objective of this document is to describe the Idaho National Laboratory (INL) Site P2 and Sustainability Program. The purpose of the program is to decrease the environmental footprint of the INL Site while providing enhanced support of its mission. The success of the program is dependent on financial and management support. The signatures on the previous page indicate INL, ICP, and AMWTP Contractor management support and dedication to the program. P2 requirements have been integrated into working procedures to ensure an effective EMS as part of an Integrated Safety Management System (ISMS). This plan focuses on programmatic functions which include environmentally preferable procurement, sustainable design, P2 and Sustainability awareness, waste generation and reduction, source reduction and recycling, energy management, and pollution prevention opportunity assessments. The INL Site P2 and Sustainability Program is administratively

  6. Global positioning site environment evaluator

    International Nuclear Information System (INIS)

    Leffler, S.; Reeser, H.G.; Zaker, E.; Hansen, W.; Sikorski, R.W.

    1990-01-01

    Development of an innovative, integrated, automated system (Global Positioning Site Environment Evaluator - GPSEETM) for surveying contaminated waste sites is described. This system makes novel use of the Global Positioning System (GPS) satellite constellation for establishing specific locations and current times for surveying radioactive, hazardous, or mixed-waste sites. GPSEE may also be used for waste site contamination surveys after remediation activities to ensure environmental remediation is complete. A base station is established for collecting and recording data and directing field operations for field stations which may be located many miles from the base station. The field operators collect site surveying and contamination data utilizing a variety of chemical and radiological sensors. A major goal for the data collection process is to collect all data utilizing in situ sensors, thereby minimizing the need for collecting soil and water samples. Site contamination data is transmitted electronically to the base station for recording and processing. The GPSEE system is being developed for use at DOE/DOD and a variety of industrial facilities. 3 figs

  7. Containment long-term operational integrity--a 1988 status report

    International Nuclear Information System (INIS)

    Sammataro, R.F.

    1988-01-01

    Design and in-service codes and standards provide a comprehensive set of requirements for containment design, construction, inspection, testing and repair. Metal and concrete containments must be designed, fabricated, constructed, inspected, tested and maintained to quality standards commensurate with the importance of the safety function to be performed. Periodic integrated leak rate tests are required to assure that containments continue to meet allowable leakage limits. Although overall performance has been quite good to date, several major containment aging and degradation mechanisms have been identified. Two pilot plant life extension studies, one for a boiling water reactor and one for a pressurized water reactor, serve as models for extending the operational integrity of present containments in the United States. Research and testing programs for determining the ultimate pressure capacity and failure mechanisms for containments under severe loading conditions and studied for extending the life of current plants beyond the present 40 year licensed lifetime are underway. This paper presents an overview of containment designs in the USA and a discussion of the regulatory and ASME Code requirements for the design, construction, in-service inspection, testing and repair for containments. Findings for containments from the pilot plant life extension studies and the ongoing containment research and testing programs are also discussed. The regulatory and ASME Code requirements for design, construction, in-service inspection and periodic integrated leakage testing together with recommendations from the plant life extension studies and containment integrity research and testing provide a basis for continued containment long-term operational integrity

  8. Total Site Heat Integration Considering Pressure Drops

    Directory of Open Access Journals (Sweden)

    Kew Hong Chew

    2015-02-01

    Full Text Available Pressure drop is an important consideration in Total Site Heat Integration (TSHI. This is due to the typically large distances between the different plants and the flow across plant elevations and equipment, including heat exchangers. Failure to consider pressure drop during utility targeting and heat exchanger network (HEN synthesis may, at best, lead to optimistic energy targets, and at worst, an inoperable system if the pumps or compressors cannot overcome the actual pressure drop. Most studies have addressed the pressure drop factor in terms of pumping cost, forbidden matches or allowable pressure drop constraints in the optimisation of HEN. This study looks at the implication of pressure drop in the context of a Total Site. The graphical Pinch-based TSHI methodology is extended to consider the pressure drop factor during the minimum energy requirement (MER targeting stage. The improved methodology provides a more realistic estimation of the MER targets and valuable insights for the implementation of the TSHI design. In the case study, when pressure drop in the steam distribution networks is considered, the heating and cooling duties increase by 14.5% and 4.5%.

  9. The integrated approach methodology for operator information evaluation

    International Nuclear Information System (INIS)

    Stroube, K.; Modarres, M.; Roush, M.; Hunt, N.; Pearce, R.

    1986-01-01

    The Integrated Approach has developed a complete method for evaluating the relative importance of operation information improvements. By use of decision trees the impact of information on success probability of a function or system can be evaluated. This approach couples goal trees and human success likelihoods to estimate anticipated consequences of a given information system

  10. DATA PROCESSING CONCEPTS FOR THE INTEGRATION OF SAR INTO OPERATIONAL VOLCANO MONITORING SYSTEMS

    Directory of Open Access Journals (Sweden)

    F. J. Meyer

    2013-05-01

    Full Text Available Remote Sensing plays a critical role in operational volcano monitoring due to the often remote locations of volcanic systems and the large spatial extent of potential eruption pre-cursor signals. Despite the all-weather capabilities of radar remote sensing and despite its high performance in monitoring change, the contribution of radar data to operational monitoring activities has been limited in the past. This is largely due to (1 the high data costs associated with radar data, (2 the slow data processing and delivery procedures, and (3 the limited temporal sampling provided by spaceborne radars. With this paper, we present new data processing and data integration techniques that mitigate some of the above mentioned limitations and allow for a meaningful integration of radar remote sensing data into operational volcano monitoring systems. The data integration concept presented here combines advanced data processing techniques with fast data access procedures in order to provide high quality radar-based volcano hazard information at improved temporal sampling rates. First performance analyses show that the integration of SAR can significantly improve the ability of operational systems to detect eruptive precursors. Therefore, the developed technology is expected to improve operational hazard detection, alerting, and management capabilities.

  11. Mucinous adenocarcinoma arising at the anastomotic site after operation for hirschsprung's disease: case report

    International Nuclear Information System (INIS)

    Kim, Hyung Soo; Yoon, Kwon Ha

    2004-01-01

    To our knowledge, rectal cancer arising at the anastomotic site after surgery for Hirschsprung's disease has not been reported. We report a case of mucinous adenocarcinoma arising at the anastomotic site after Soave operation 26 years ago

  12. On Generalized Fractional Integral Operators and the Generalized Gauss Hypergeometric Functions

    Directory of Open Access Journals (Sweden)

    Dumitru Baleanu

    2014-01-01

    Full Text Available A remarkably large number of fractional integral formulas involving the number of special functions, have been investigated by many authors. Very recently, Agarwal (National Academy Science Letters gave some integral transform and fractional integral formulas involving the Fpα,β·. In this sequel, here, we aim to establish some image formulas by applying generalized operators of the fractional integration involving Appell’s function F3(· due to Marichev-Saigo-Maeda. Some interesting special cases of our main results are also considered.

  13. Process automation system for integration and operation of Large Volume Plasma Device

    International Nuclear Information System (INIS)

    Sugandhi, R.; Srivastava, P.K.; Sanyasi, A.K.; Srivastav, Prabhakar; Awasthi, L.M.; Mattoo, S.K.

    2016-01-01

    Highlights: • Analysis and design of process automation system for Large Volume Plasma Device (LVPD). • Data flow modeling for process model development. • Modbus based data communication and interfacing. • Interface software development for subsystem control in LabVIEW. - Abstract: Large Volume Plasma Device (LVPD) has been successfully contributing towards understanding of the plasma turbulence driven by Electron Temperature Gradient (ETG), considered as a major contributor for the plasma loss in the fusion devices. Large size of the device imposes certain difficulties in the operation, such as access of the diagnostics, manual control of subsystems and large number of signals monitoring etc. To achieve integrated operation of the machine, automation is essential for the enhanced performance and operational efficiency. Recently, the machine is undergoing major upgradation for the new physics experiments. The new operation and control system consists of following: (1) PXIe based fast data acquisition system for the equipped diagnostics; (2) Modbus based Process Automation System (PAS) for the subsystem controls and (3) Data Utilization System (DUS) for efficient storage, processing and retrieval of the acquired data. In the ongoing development, data flow model of the machine’s operation has been developed. As a proof of concept, following two subsystems have been successfully integrated: (1) Filament Power Supply (FPS) for the heating of W- filaments based plasma source and (2) Probe Positioning System (PPS) for control of 12 number of linear probe drives for a travel length of 100 cm. The process model of the vacuum production system has been prepared and validated against acquired pressure data. In the next upgrade, all the subsystems of the machine will be integrated in a systematic manner. The automation backbone is based on 4-wire multi-drop serial interface (RS485) using Modbus communication protocol. Software is developed on LabVIEW platform using

  14. Process automation system for integration and operation of Large Volume Plasma Device

    Energy Technology Data Exchange (ETDEWEB)

    Sugandhi, R., E-mail: ritesh@ipr.res.in; Srivastava, P.K.; Sanyasi, A.K.; Srivastav, Prabhakar; Awasthi, L.M.; Mattoo, S.K.

    2016-11-15

    Highlights: • Analysis and design of process automation system for Large Volume Plasma Device (LVPD). • Data flow modeling for process model development. • Modbus based data communication and interfacing. • Interface software development for subsystem control in LabVIEW. - Abstract: Large Volume Plasma Device (LVPD) has been successfully contributing towards understanding of the plasma turbulence driven by Electron Temperature Gradient (ETG), considered as a major contributor for the plasma loss in the fusion devices. Large size of the device imposes certain difficulties in the operation, such as access of the diagnostics, manual control of subsystems and large number of signals monitoring etc. To achieve integrated operation of the machine, automation is essential for the enhanced performance and operational efficiency. Recently, the machine is undergoing major upgradation for the new physics experiments. The new operation and control system consists of following: (1) PXIe based fast data acquisition system for the equipped diagnostics; (2) Modbus based Process Automation System (PAS) for the subsystem controls and (3) Data Utilization System (DUS) for efficient storage, processing and retrieval of the acquired data. In the ongoing development, data flow model of the machine’s operation has been developed. As a proof of concept, following two subsystems have been successfully integrated: (1) Filament Power Supply (FPS) for the heating of W- filaments based plasma source and (2) Probe Positioning System (PPS) for control of 12 number of linear probe drives for a travel length of 100 cm. The process model of the vacuum production system has been prepared and validated against acquired pressure data. In the next upgrade, all the subsystems of the machine will be integrated in a systematic manner. The automation backbone is based on 4-wire multi-drop serial interface (RS485) using Modbus communication protocol. Software is developed on LabVIEW platform using

  15. Characteristics of the volatile organic compounds -- Arid Integrated Demonstration Site

    International Nuclear Information System (INIS)

    Last, G.V.; Lenhard, R.J.; Bjornstad, B.N.; Evans, J.C.; Roberson, K.R.; Spane, F.A.; Amonette, J.E.; Rockhold, M.L.

    1991-10-01

    The Volatile Organic Compounds -- Arid Integrated Demonstration Program (VOC-Arid ID) is targeted at demonstration and testing of technologies for the evaluation and cleanup of volatile organic compounds and associated contaminants at arid DOE sites. The initial demonstration site is an area of carbon tetrachloride (CCl 4 ) contamination located near the center of the Hanford Site. The movement of CCl 4 and other volatile organic contaminants in the subsurface is very complex. The problem at the Hanford Site is further complicated by the concurrent discharge of other waste constituents including acids, lard oil, organic phosphates, and transuranic radionuclides. In addition, the subsurface environment is very complex, with large spatial variabilities in hydraulic properties. A thorough understanding of the problem is essential to the selection of appropriate containment, retrieval, and/or in situ remedial technologies. The effectiveness of remedial technologies depends on knowing where the contaminants are, how they are held up in a given physical and chemical subsurface environment; and knowing the physical, chemical, and microbiological changes that are induced by the various remedial technologies

  16. Integrating solar PV (photovoltaics) in utility system operations: Analytical framework and Arizona case study

    International Nuclear Information System (INIS)

    Wu, Jing; Botterud, Audun; Mills, Andrew; Zhou, Zhi; Hodge, Bri-Mathias; Heaney, Mike

    2015-01-01

    A systematic framework is proposed to estimate the impact on operating costs due to uncertainty and variability in renewable resources. The framework quantifies the integration costs associated with sub-hourly variability and uncertainty as well as day-ahead forecasting errors in solar PV (photovoltaics) power. A case study illustrates how changes in system operations may affect these costs for a utility in the southwestern United States (Arizona Public Service Company). We conduct an extensive sensitivity analysis under different assumptions about balancing reserves, system flexibility, fuel prices, and forecasting errors. We find that high solar PV penetrations may lead to operational challenges, particularly during low-load and high solar periods. Increased system flexibility is essential for minimizing integration costs and maintaining reliability. In a set of sensitivity cases where such flexibility is provided, in part, by flexible operations of nuclear power plants, the estimated integration costs vary between $1.0 and $4.4/MWh-PV for a PV penetration level of 17%. The integration costs are primarily due to higher needs for hour-ahead balancing reserves to address the increased sub-hourly variability and uncertainty in the PV resource. - Highlights: • We propose an analytical framework to estimate grid integration costs for solar PV. • Increased operating costs from variability and uncertainty in solar PV are computed. • A case study of a utility in Arizona is conducted. • Grid integration costs are found in the $1.0–4.4/MWh range for a 17% PV penetration. • Increased system flexibility is essential for minimizing grid integration costs

  17. Kurzweil integral representation of interacting Prandtl-Ishlinskii operators

    Czech Academy of Sciences Publication Activity Database

    Krejčí, Pavel; Lamba, H.; Melnik, S.; Rachinskii, D.

    2015-01-01

    Roč. 20, č. 9 (2015), s. 2949-2965 ISSN 1531-3492 R&D Projects: GA ČR(CZ) GA15-12227S Institutional support: RVO:67985840 Keywords : Kurzweil integral * hysteresis * Prandtl-Ishlinskii operator Subject RIV: BA - General Mathematics Impact factor: 1.227, year: 2015 http://www.aimsciences.org/journals/displayArticlesnew.jsp?paperID=11649

  18. Geothermal electricity generation and desalination: an integrated process design to conserve latent heat with operational improvements

    KAUST Repository

    Missimer, Thomas M.; Ng, Kim Choon; Thuw, Kyaw; Wakil Shahzad, Muhammad

    2016-01-01

    A new process combination is proposed to link geothermal electricity generation with desalination. The concept involves maximizing the utilization of harvested latent heat by passing the turbine exhaust steam into a multiple effect distillation system and then into an adsorption desalination system. Processes are fully integrated to produce electricity, desalted water for consumer consumption, and make-up water for the geothermal extraction system. Further improvements in operational efficiency are achieved by adding a seawater reverse osmosis system to the site to utilize some of the generated electricity and using on-site aquifer storage and recovery to maximize water production with tailoring of seasonal capacity requirements and to meet facility maintenance requirements. The concept proposed conserves geothermally harvested latent heat and maximizes the economics of geothermal energy development. Development of a fully renewable energy electric generation-desalination-aquifer storage campus is introduced within the framework of geothermal energy development. © 2016 The Author(s). Published by Taylor & Francis

  19. Geothermal electricity generation and desalination: an integrated process design to conserve latent heat with operational improvements

    KAUST Repository

    Missimer, Thomas M.

    2016-02-05

    A new process combination is proposed to link geothermal electricity generation with desalination. The concept involves maximizing the utilization of harvested latent heat by passing the turbine exhaust steam into a multiple effect distillation system and then into an adsorption desalination system. Processes are fully integrated to produce electricity, desalted water for consumer consumption, and make-up water for the geothermal extraction system. Further improvements in operational efficiency are achieved by adding a seawater reverse osmosis system to the site to utilize some of the generated electricity and using on-site aquifer storage and recovery to maximize water production with tailoring of seasonal capacity requirements and to meet facility maintenance requirements. The concept proposed conserves geothermally harvested latent heat and maximizes the economics of geothermal energy development. Development of a fully renewable energy electric generation-desalination-aquifer storage campus is introduced within the framework of geothermal energy development. © 2016 The Author(s). Published by Taylor & Francis

  20. Hanford Site Solid Waste Landfill permit application. Revision 1

    International Nuclear Information System (INIS)

    1993-01-01

    Both nonhazardous and nonradioactive sanitary solid waste are generated at the Hanford Site. This permit application describes the manner in which the Solid Waste Landfill will be operated. A description is provided of the landfill, including applicable locational, general facility, and landfilling standards. The characteristics and quantity of the waste disposed of are discussed. The regional and site geology and hydrology and the groundwater and vadose zone quality beneath the landfill are reviewed. A plan is included of operation, closure, and postclosure. This report addresses the operational cover, environmental controls, personnel requirements, inspections, recordkeeping, reporting, and site security. The integration of closure and postclosure activities between the Solid Waste Landfill and adjacent Nonradioactive Dangerous Waste Landfill is discussed

  1. Integrated Bidding and Operating Strategies for Wind-Storage Systems

    DEFF Research Database (Denmark)

    Ding, Huajie; Pinson, Pierre; Hu, Zechun

    2016-01-01

    Due to their flexible charging and discharging capabilities, energy storage systems (ESS) are considered a promising complement to wind farms (WFs) participating in electricity markets. This paper presents integrated day-ahead bidding and real-time operation strategies for a wind-storage system...

  2. Hanford Environmental Information System (HEIS) Operator`s Manual. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Schreck, R.I.

    1991-10-01

    The Hanford Environmental Information System (HEIS) is a consolidated set of automated resources that effectively manage the data gathered during environmental monitoring and restoration of the Hanford Site. The HEIS includes an integrated database that provides consistent and current data to all users and promotes sharing of data by the entire user community. This manual describes the facilities available to the operational user who is responsible for data entry, processing, scheduling, reporting, and quality assurance. A companion manual, the HEIS User`s Manual, describes the facilities available-to the scientist, engineer, or manager who uses the system for environmental monitoring, assessment, and restoration planning; and to the regulator who is responsible for reviewing Hanford Site operations against regulatory requirements and guidelines.

  3. 76 FR 17145 - Agency Information Collection Activities: Business Transformation-Automated Integrated Operating...

    Science.gov (United States)

    2011-03-28

    ... Collection Activities: Business Transformation--Automated Integrated Operating Environment (IOE), New... through efforts like USCIS' Business Transformation initiative. The IOE will be implemented by USCIS and... information collection. (2) Title of the Form/Collection: Business Transformation-- Automated Integrated...

  4. Setting and solving several factorization problems for integral operators

    International Nuclear Information System (INIS)

    Engibaryan, N B

    2000-01-01

    The problem of factorization I-K=(I-U - )(I-U + ), is considered. Here I is the identity operator, K is a fixed integral operator of Fredholm type: (Kf)(x)=∫ a b k(x,t)f(t)dt, -∞≤a ± are unknown upper and lower Volterra operators. Classes of generalized Volterra operators U ± are introduced such that I-U ± are not necessarily invertible operators in the spaces of functions on (a,b) under consideration. A combination of the method of non-linear factorization equations and a priori estimates brings forth new results on the existence and properties of the solution to this problem for k≥0, both in the subcritical case μ + and U - vanish on some parts S - and S + of the domain S=(a,b) 2 such that S + union S - =S

  5. Site-Specific Integration of Exogenous Genes Using Genome Editing Technologies in Zebrafish

    Directory of Open Access Journals (Sweden)

    Atsuo Kawahara

    2016-05-01

    Full Text Available The zebrafish (Danio rerio is an ideal vertebrate model to investigate the developmental molecular mechanism of organogenesis and regeneration. Recent innovation in genome editing technologies, such as zinc finger nucleases (ZFNs, transcription activator-like effector nucleases (TALENs and the clustered regularly interspaced short palindromic repeats (CRISPR/CRISPR associated protein 9 (Cas9 system, have allowed researchers to generate diverse genomic modifications in whole animals and in cultured cells. The CRISPR/Cas9 and TALEN techniques frequently induce DNA double-strand breaks (DSBs at the targeted gene, resulting in frameshift-mediated gene disruption. As a useful application of genome editing technology, several groups have recently reported efficient site-specific integration of exogenous genes into targeted genomic loci. In this review, we provide an overview of TALEN- and CRISPR/Cas9-mediated site-specific integration of exogenous genes in zebrafish.

  6. Strategies Used by Facilities in Uganda to Integrate Family Planning ...

    African Journals Online (AJOL)

    Erah

    assistance and coaching from the core team, we integrated routine site/field operations. The performance of each site was monitored using the three FP-HIV care integration indicators – proportion of HIV-positive patients of reproductive age who were: 1) counseled on FP methods at every clinic visit, 2) using at least one FP ...

  7. Seismic aftershock monitoring for on-site inspection purposes. Experience from Integrated Field Exercise 2008.

    Science.gov (United States)

    Labak, P.; Arndt, R.; Villagran, M.

    2009-04-01

    One of the sub-goals of the Integrated Field Experiment in 2008 (IFE08) in Kazakhstan was testing the prototype elements of the Seismic aftershock monitoring system (SAMS) for on-site inspection purposes. The task of the SAMS is to collect the facts, which should help to clarify nature of the triggering event. Therefore the SAMS has to be capable to detect and identify events as small as magnitude -2 in the inspection area size up to 1000 km2. Equipment for 30 mini-arrays and 10 3-component stations represented the field equipment of the SAMS. Each mini-array consisted of a central 3-component seismometer and 3 vertical seismometers at the distance about 100 m from the central seismometer. The mini-arrays covered approximately 80% of surrogate inspection area (IA) on the territory of former Semipalatinsk test site. Most of the stations were installed during the first four days of field operations by the seismic sub-team, which consisted of 10 seismologists. SAMS data center comprised 2 IBM Blade centers and 8 working places for data archiving, detection list production and event analysis. A prototype of SAMS software was tested. Average daily amount of collected raw data was 15-30 GB and increased according to the amount of stations entering operation. Routine manual data screening and data analyses were performed by 2-6 subteam members. Automatic screening was used for selected time intervals. Screening was performed using the Sonoview program in frequency domain and using the Geotool and Hypolines programs for screening in time domain. The screening results were merged into the master event list. The master event list served as a basis of detailed analysis of unclear events and events identified to be potentially in the IA. Detailed analysis of events to be potentially in the IA was performed by the Hypoline and Geotool programs. In addition, the Hyposimplex and Hypocenter programs were also used for localization of events. The results of analysis were integrated

  8. From organizational integration to clinical integration: analysis of the path between one level of integration to another using official documents

    Science.gov (United States)

    Mandza, Matey; Gagnon, Dominique; Carrier, Sébastien; Belzile, Louise; Demers, Louis

    2010-01-01

    Purpose Services’ integration comprises organizational, normative, economic, informational and clinical dimensions. Since 2004, the province of Quebec has devoted significant efforts to unify the governance of the main health and social care organizations of its various territories. Notwithstanding the uniformity of the national plan’s prescription, the territorial integration modalities greatly vary across the province. Theory This research is based upon a conceptual model of integration that comprises six components: inter-organizational partnership, case management, standardized assessment, a single entry point, a standardized service planning tool and a shared clinical file. Methods We conducted an embedded case study in six contrasted sites in terms of their level of integration. All documents prescribing the implementation of integration were retrieved and analyzed. Results and conclusions The analyzed documents demonstrate a growing local appropriation of the current integrative reform. Interestingly however, no link seems to exist between the quality of local prescriptions and the level of integration achieved in each site. This finding leads us to hypothesize that the variable quality of the operational accompaniment offered to implement these prescriptions is a variable in play.

  9. Nevada test site radionuclide inventory and distribution: project operations plan

    International Nuclear Information System (INIS)

    Kordas, J.F.; Anspaugh, L.R.

    1982-01-01

    This document is the operational plan for conducting the Radionuclide Inventory and Distribution Program (RIDP) at the Nevada Test Site (NTS). The basic objective of this program is to inventory the significant radionuclides of NTS origin in NTS surface soil. The expected duration of the program is five years. This plan includes the program objectives, methods, organization, and schedules

  10. Operational radioactive waste management plan for the Nevada Test Site

    International Nuclear Information System (INIS)

    1980-11-01

    The Operational Radioactive Waste Management Plan for the Nevada Test Site establishes procedures and methods for the safe shipping, receiving, processing, disposal, and storage of radioactive waste. Included are NTS radioactive waste disposition program guidelines, procedures for radioactive waste management, a description of storage and disposal areas and facilities, and a glossary of specifications and requirements

  11. High-integrity databases for helicopter operations

    Science.gov (United States)

    Pschierer, Christian; Schiefele, Jens; Lüthy, Juerg

    2009-05-01

    Helicopter Emergency Medical Service missions (HEMS) impose a high workload on pilots due to short preparation time, operations in low level flight, and landings in unknown areas. The research project PILAS, a cooperation between Eurocopter, Diehl Avionics, DLR, EADS, Euro Telematik, ESG, Jeppesen, the Universities of Darmstadt and Munich, and funded by the German government, approached this problem by researching a pilot assistance system which supports the pilots during all phases of flight. The databases required for the specified helicopter missions include different types of topological and cultural data for graphical display on the SVS system, AMDB data for operations at airports and helipads, and navigation data for IFR segments. The most critical databases for the PILAS system however are highly accurate terrain and obstacle data. While RTCA DO-276 specifies high accuracies and integrities only for the areas around airports, HEMS helicopters typically operate outside of these controlled areas and thus require highly reliable terrain and obstacle data for their designated response areas. This data has been generated by a LIDAR scan of the specified test region. Obstacles have been extracted into a vector format. This paper includes a short overview of the complete PILAS system and then focus on the generation of the required high quality databases.

  12. ADVANCED COMPRESSOR ENGINE CONTROLS TO ENHANCE OPERATION, RELIABILITY AND INTEGRITY

    Energy Technology Data Exchange (ETDEWEB)

    Gary D. Bourn; Jess W. Gingrich; Jack A. Smith

    2004-03-01

    This document is the final report for the ''Advanced Compressor Engine Controls to Enhance Operation, Reliability, and Integrity'' project. SwRI conducted this project for DOE in conjunction with Cooper Compression, under DOE contract number DE-FC26-03NT41859. This report addresses an investigation of engine controls for integral compressor engines and the development of control strategies that implement closed-loop NOX emissions feedback.

  13. Research on the performance evaluation of agricultural products supply chain integrated operation

    Science.gov (United States)

    Jiang, Jiake; Wang, Xifu; Liu, Yang

    2017-04-01

    The agricultural product supply chain integrated operation can ensure the quality and efficiency of agricultural products, and achieve the optimal goal of low cost and high service. This paper establishes a performance evaluation index system of agricultural products supply chain integration operation based on the development status of agricultural products and SCOR, BSC and KPI model. And then, we constructing rough set theory and BP neural network comprehensive evaluation model with the aid of Rosetta and MATLAB tools and the case study is about the development of agricultural products integrated supply chain in Jing-Jin-Ji region. And finally, we obtain the corresponding performance results, and give some improvement measures and management recommendations to the managers.

  14. Steam generator tube integrity requirements and operating experience in the United States

    International Nuclear Information System (INIS)

    Karwoski, K.J.

    2009-01-01

    Steam generator tube integrity is important to the safe operation of pressurized-water reactors. For ensuring tube integrity, the U.S. Nuclear Regulatory Commission uses a regulatory framework that is largely performance based. This performance-based framework is supplemented with some prescriptive requirements. The framework recognizes that there are three combinations of tube materials and heat treatments currently used in the United States and that the operating experience depends, in part, on the type of material used. This paper summarizes the regulatory framework for ensuring steam generator tube integrity, it highlights the current status of steam generators, and it highlights some of the steam generator issues and challenges that exist in the United States. (author)

  15. On New p-Valent Meromorphic Function Involving Certain Differential and Integral Operators

    Directory of Open Access Journals (Sweden)

    Aabed Mohammed

    2014-01-01

    Full Text Available We define new subclasses of meromorphic p-valent functions by using certain differential operator. Combining the differential operator and certain integral operator, we introduce a general p-valent meromorphic function. Then we prove the sufficient conditions for the function in order to be in the new subclasses.

  16. Integrated circuits and logic operations based on single-layer MoS2.

    Science.gov (United States)

    Radisavljevic, Branimir; Whitwick, Michael Brian; Kis, Andras

    2011-12-27

    Logic circuits and the ability to amplify electrical signals form the functional backbone of electronics along with the possibility to integrate multiple elements on the same chip. The miniaturization of electronic circuits is expected to reach fundamental limits in the near future. Two-dimensional materials such as single-layer MoS(2) represent the ultimate limit of miniaturization in the vertical dimension, are interesting as building blocks of low-power nanoelectronic devices, and are suitable for integration due to their planar geometry. Because they are less than 1 nm thin, 2D materials in transistors could also lead to reduced short channel effects and result in fabrication of smaller and more power-efficient transistors. Here, we report on the first integrated circuit based on a two-dimensional semiconductor MoS(2). Our integrated circuits are capable of operating as inverters, converting logical "1" into logical "0", with room-temperature voltage gain higher than 1, making them suitable for incorporation into digital circuits. We also show that electrical circuits composed of single-layer MoS(2) transistors are capable of performing the NOR logic operation, the basis from which all logical operations and full digital functionality can be deduced.

  17. Hanford Site waste management and environmental restoration integration plan

    International Nuclear Information System (INIS)

    Merrick, D.L.

    1990-01-01

    The ''Hanford Site Waste Management and Environmental Restoration Integration Plan'' describes major actions leading to waste disposal and site remediation. The primary purpose of this document is to provide a management tool for use by executives who need to quickly comprehend the waste management and environmental restoration programs. The Waste Management and Environmental Restoration Programs have been divided into missions. Waste Management consists of five missions: double-shell tank (DST) wastes; single-shell tank (SST) wastes (surveillance and interim storage, stabilization, and isolation); encapsulated cesium and strontium; solid wastes; and liquid effluents. Environmental Restoration consists of two missions: past practice units (PPU) (including characterization and assessment of SST wastes) and surplus facilities. For convenience, both aspects of SST wastes are discussed in one place. A general category of supporting activities is also included. 20 refs., 14 figs., 7 tabs

  18. Research and Application of Construction of Operation Integration for Smart Power Distribution and Consumption Based on “Integration of Marketing with Distribution”

    Directory of Open Access Journals (Sweden)

    Zhenbao Feng

    2014-05-01

    Full Text Available The “information integrated platform of marketing and distribution integration system” researched and developed by this article is an advanced application platform to concurrently design and develop the automation of marketing and power distribution through integration and analysis of existing data based on the data platform of Jiaozuo Power Supply Corporation. It uses data mining and data bus technology, uniform analysis of comprehensive marketing and distribution data. And it conducts a real time monitoring on power utilization information for marketing and early warning maintenance business of power distribution according to electric business model, which realizes an integration of marketing and distribution business, achieves the target of integrated operation of marketing and distribution, improves the operation level of business, reduces maintenance costs of distribution grid, increases electricity sales of distribution grid and provide reliable practical basis for operation and maintenance of Jiaozuo power marketing and distribution.

  19. H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development, is seen here visiting Microcosm, CERN's on-site exhibition centre. Photo 01: H.S.H. Prince Radu of Hohenzollern-Veringen (right) with his personal adviser Cornel Comsa inside Microcosm's full-scale model of a six-metre section of the LHC. Photos 04-06: H.S.H. Prince Radu of Hohenzollern-Veringen with Emma Sanders from ETT Division.

  20. Integrated management of operations in Santos Basin: methodology applied to a new philosophy of operations

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Leandro Leonardo; Lima, Claudio Benevenuto de Campos [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil); Derenzi Neto, Dario [Accenture, Rio de Janeiro, RJ (Brazil); Pinto, Vladimir Steffen [Soda IT, Rio de Janeiro, RJ (Brazil); Lima, Gilson Brito Alves [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil)

    2012-07-01

    The objective of this paper is to present the methodology used to develop the Integrated Management of Operations (GIOp) project in Santos Basin Operational Unit (UO-BS) in the South-Southeast Exploration and Production area of PETROBRAS. The following text describes how the activities were carried out to gather improvements opportunities and to design To-Be processes, considering the challenging environment of the Santos Basin in the coming years. At the end of more than 12 months of work, more than 50 processes and sub-processes were redesigned, involving a multidisciplinary team in the areas of operations, maintenance, safety, health and environment, flow assurance, wells, reservoirs and planning. (author)

  1. Optimum Operating Room Environment for the Prevention of Surgical Site Infections.

    Science.gov (United States)

    Gaines, Sara; Luo, James N; Gilbert, Jack; Zaborina, Olga; Alverdy, John C

    Surgical site infections (SSI), whether they be incisional or deep, can entail major morbidity and death to patients and additional cost to the healthcare system. A significant amount of effort has gone into optimizing the surgical patient and the operating room environment to reduce SSI. Relevant guidelines and literature were reviewed. The modern practice of surgical antisepsis involves the employment of strict sterile techniques inside the operating room. Extensive guidelines are available regarding the proper operating room antisepsis as well as pre-operative preparation. The use of pre-operative antimicrobial prophylaxis has become increasingly prevalent, which also presents the challenge of opportunistic and nosocomial infections. Ongoing investigative efforts have brought about a greater appreciation of the surgical patient's endogenous microflora, use of non-bactericidal small molecules, and pre-operative microbial screening. Systematic protocols exist for optimizing the surgical sterility of the operating room to prevent SSIs. Ongoing research efforts aim to improve the precision of peri-operative antisepsis measures and personalize these measures to tailor the patient's unique microbial environment.

  2. Fractional Integral and Generalized Stieltjes Transforms for Hypergeometric Functions as Transmutation Operators

    NARCIS (Netherlands)

    Koornwinder, T.H.

    2015-01-01

    For each of the eight n-th derivative parameter changing formulas for Gauss hypergeometric functions a corresponding fractional integration formula is given. For both types of formulas the differential or integral operator is intertwining between two actions of the hypergeometric differential

  3. An integrated building demolition and waste planning model for the Fernald Site

    International Nuclear Information System (INIS)

    Hampshire, L.H.; Clark, T.R.; Frost, M.L.; Reising, J.W.

    1995-01-01

    The Fernald DOE site will begin full-scale remediation of buildings under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) during the 1995 fiscal year pursuant to a signed Record of Decision. This effort is currently estimated to cost $350 million and span a minimum duration of 8 years, if funding is not a constraint. The identification of the most viable sequence and schedule for the effort involved the development of an integrated planning model and the commissioning of a sitewide planning team. The resulting work product represents the best combination of assumptions and calculations possible at this time and provides information necessary for compliance with the CERCLA Remedial Design documentation requirements for the over 230 component structures governed by the decision. Sequence and integrated schedule development for the decontamination and dismantlement (D ampersand D) of Fernald structures has involved evaluation of current and future utilization of structures, availability of waste storage and staging space, the needs and impacts of other on-going Fernald projects, Resource Conservation and Recovery Act (RCRA) waste management and remediation projects, the layout of site utilities, site hydrology, and the potential sizing, location, and construction rates for an on-property disposal cell

  4. Building reactor operator sustain expert system with C language integrated production system

    International Nuclear Information System (INIS)

    Ouyang Qin; Hu Shouyin; Wang Ruipian

    2002-01-01

    The development of the reactor operator sustain expert system is introduced, the capability of building reactor operator sustain expert system is discussed with C Language Integrated Production System (Clips), and a simple antitype of expert system is illustrated. The limitation of building reactor operator sustain expert system with Clips is also discussed

  5. Performing derivative and integral operations for optical waves with optical metamaterials

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Cun-Li [College of Engineering, Nanjing Agriculture University, Nanjing Jiangsu, 210031 (China); College of Science, Nanjing Agriculture University, Nanjing Jiangsu, 210095 (China); Zhao, Zhi-Gang; Li, Xiao-Lin [College of Engineering, Nanjing Agriculture University, Nanjing Jiangsu, 210031 (China); Yang, Hong-Wei, E-mail: phd_hwyang@njau.edu.cn [College of Science, Nanjing Agriculture University, Nanjing Jiangsu, 210095 (China)

    2016-12-01

    The graded refractive index waveguides can perform Fourier transform for an optical wave. According to this characteristic, simpler optical metamaterials with three waveguides are theoretically proposed, in which all of the waveguides are materials with a positive refractive index. By selecting the appropriate refractive index and structure size, the theory and simulations demonstrated that these metamaterials can perform mathematical operations for the outline of incident optical waves, including the first-order derivative, second-order derivative and the integral. - Highlights: • The derivative and integral operations of optical waves are achieved with a simpler model. • Both negative and positive refractive index boast the same functions. • The mathematical operations can be implemented only by changing the refractive index of the intermediate material. • The results will greatly expand the possible applications, including photon computers, picture processing, video displays and data storage.

  6. 78 FR 61389 - Sanyo Solar of Oregon, LLC, Wafer Slicing and Quality Control Operations, Including On-Site...

    Science.gov (United States)

    2013-10-03

    ..., LLC, Wafer Slicing and Quality Control Operations, Including On-Site Leased Workers From Brown and... Quality Control Operations, Salem, Oregon, including on-site leased workers from Brown and Dunton, Inc... and included workers who supplied quality control and support functions. The company reports that...

  7. Framework for Integrating Safety, Operations, Security, and Safeguards in the Design and Operation of Nuclear Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Darby, John L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Horak, Karl Emanuel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); LaChance, Jeffrey L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Tolk, Keith Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Whitehead, Donnie Wayne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2007-10-01

    The US is currently on the brink of a nuclear renaissance that will result in near-term construction of new nuclear power plants. In addition, the Department of Energy’s (DOE) ambitious new Global Nuclear Energy Partnership (GNEP) program includes facilities for reprocessing spent nuclear fuel and reactors for transmuting safeguards material. The use of nuclear power and material has inherent safety, security, and safeguards (SSS) concerns that can impact the operation of the facilities. Recent concern over terrorist attacks and nuclear proliferation led to an increased emphasis on security and safeguard issues as well as the more traditional safety emphasis. To meet both domestic and international requirements, nuclear facilities include specific SSS measures that are identified and evaluated through the use of detailed analysis techniques. In the past, these individual assessments have not been integrated, which led to inefficient and costly design and operational requirements. This report provides a framework for a new paradigm where safety, operations, security, and safeguards (SOSS) are integrated into the design and operation of a new facility to decrease cost and increase effectiveness. Although the focus of this framework is on new nuclear facilities, most of the concepts could be applied to any new, high-risk facility.

  8. A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology.

    Science.gov (United States)

    Ustek, Duran; Sirma, Sema; Gumus, Ergun; Arikan, Muzaffer; Cakiris, Aris; Abaci, Neslihan; Mathew, Jaicy; Emrence, Zeliha; Azakli, Hulya; Cosan, Fulya; Cakar, Atilla; Parlak, Mahmut; Kursun, Olcay

    2012-10-01

    One application of next-generation sequencing (NGS) is the targeted resequencing of interested genes which has not been used in viral integration site analysis of gene therapy applications. Here, we combined targeted sequence capture array and next generation sequencing to address the whole genome profiling of viral integration sites. Human 293T and K562 cells were transduced with a HIV-1 derived vector. A custom made DNA probe sets targeted pLVTHM vector used to capture lentiviral vector/human genome junctions. The captured DNA was sequenced using GS FLX platform. Seven thousand four hundred and eighty four human genome sequences flanking the long terminal repeats (LTR) of pLVTHM fragment sequences matched with an identity of at least 98% and minimum 50 bp criteria in both cells. In total, 203 unique integration sites were identified. The integrations in both cell lines were totally distant from the CpG islands and from the transcription start sites and preferentially located in introns. A comparison between the two cell lines showed that the lentiviral-transduced DNA does not have the same preferred regions in the two different cell lines. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Remedial investigation/feasibility study work plan for the 100-FR-3 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Figure 1-1 shows the location of these areas. Under the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1990a), signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1,000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste, and other CERCLA hazardous substances. This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-FR-3 operable unit. The 100-K Area consists of the 100-FR-3 groundwater operable unit and two source operable units. The 100-FR-3 operable unit includes all contamination found in the aquifer soils and water beneath the 100-F Area. Source operable units include facilities and unplanned release sites that are potential sources of contamination. A separate work plan has been initiated for the 100-FR-1 source operable unit (DOE-RL 1992a)

  10. Remedial investigation/feasibility study work plan for the 100-FR-1 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-08-01

    Four areas of the Hanford Site (the 100, 200,300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1990a), signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1,000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste, and other CERCLA hazardous substances. This work plan and the attached supporting project plans establish the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-FR-1 operable unit. The 100-FR-1 source operable unit is one of two source operable units in the 100-F Area. Source operable units include facilities and unplanned release sites that are potential sources of hazardous substance contamination. The groundwater affected or potentially affected by the entire 100-F Area is considered as a separate operable unit, the 100-FR-3 groundwater operable unit. A separate work plan has been initiated for the 100-FR-3 operable unit (DOE/RL 1992a)

  11. Integrating SAR and derived products into operational volcano monitoring and decision support systems

    Science.gov (United States)

    Meyer, F. J.; McAlpin, D. B.; Gong, W.; Ajadi, O.; Arko, S.; Webley, P. W.; Dehn, J.

    2015-02-01

    Remote sensing plays a critical role in operational volcano monitoring due to the often remote locations of volcanic systems and the large spatial extent of potential eruption pre-cursor signals. Despite the all-weather capabilities of radar remote sensing and its high performance in monitoring of change, the contribution of radar data to operational monitoring activities has been limited in the past. This is largely due to: (1) the high costs associated with radar data; (2) traditionally slow data processing and delivery procedures; and (3) the limited temporal sampling provided by spaceborne radars. With this paper, we present new data processing and data integration techniques that mitigate some of these limitations and allow for a meaningful integration of radar data into operational volcano monitoring decision support systems. Specifically, we present fast data access procedures as well as new approaches to multi-track processing that improve near real-time data access and temporal sampling of volcanic systems with SAR data. We introduce phase-based (coherent) and amplitude-based (incoherent) change detection procedures that are able to extract dense time series of hazard information from these data. For a demonstration, we present an integration of our processing system with an operational volcano monitoring system that was developed for use by the Alaska Volcano Observatory (AVO). Through an application to a historic eruption, we show that the integration of SAR into systems such as AVO can significantly improve the ability of operational systems to detect eruptive precursors. Therefore, the developed technology is expected to improve operational hazard detection, alerting, and management capabilities.

  12. ICAROUS - Integrated Configurable Algorithms for Reliable Operations Of Unmanned Systems

    Science.gov (United States)

    Consiglio, María; Muñoz, César; Hagen, George; Narkawicz, Anthony; Balachandran, Swee

    2016-01-01

    NASA's Unmanned Aerial System (UAS) Traffic Management (UTM) project aims at enabling near-term, safe operations of small UAS vehicles in uncontrolled airspace, i.e., Class G airspace. A far-term goal of UTM research and development is to accommodate the expected rise in small UAS traffic density throughout the National Airspace System (NAS) at low altitudes for beyond visual line-of-sight operations. This paper describes a new capability referred to as ICAROUS (Integrated Configurable Algorithms for Reliable Operations of Unmanned Systems), which is being developed under the UTM project. ICAROUS is a software architecture comprised of highly assured algorithms for building safety-centric, autonomous, unmanned aircraft applications. Central to the development of the ICAROUS algorithms is the use of well-established formal methods to guarantee higher levels of safety assurance by monitoring and bounding the behavior of autonomous systems. The core autonomy-enabling capabilities in ICAROUS include constraint conformance monitoring and contingency control functions. ICAROUS also provides a highly configurable user interface that enables the modular integration of mission-specific software components.

  13. On the factorization of integral operators on spaces of summable functions

    International Nuclear Information System (INIS)

    Engibaryan, Norayr B

    2009-01-01

    We consider the factorization I-K=(I-U + )(I-U - ), where I is the identity operator, K is an integral operator acting on some Banach space of functions summable with respect to a measure μ on (a,b) subset of (-∞,+∞) continuous relative to the Lebesgue measure, (Kf)(x)=∫ a b k(x,t)f(t)μ(dt), x element of (a,b), and U ± are the desired Volterra operators. A necessary and sufficient condition is found for the existence of this factorization for a rather wide class of operators K with positive kernels and for Hilbert-Schmidt operators.

  14. Site Environmental Report for calendar year 1998, DOE operations at Rocketdyne Propulsion and Power

    International Nuclear Information System (INIS)

    Rutherford, P.D.

    1999-01-01

    This Annual Site Environmental Report for 1998 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of the Rocketdyne Santa Susana Field Laboratory (SSFL) and De Soto facilities. In the past, these operations included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials, under the Atomics International (AI) Division. Other activities included the operation of large-scale liquid metal facilities for testing of liquid metal fast breeder components at the Energy Technology Engineering Center (ETEC), a government-owned company-operated, test facility within Area IV. AI was merged into Rocketdyne in 1984 and many of the AI functions were transferred to existing Rocketdyne departments. All nuclear work was terminated in 1988, and subsequently, all radiological work has been directed toward decontamination and decommissioning (D and D) of the previously used nuclear facilities and associated site areas. Large-scale D and D activities of the sodium test facilities began in 1996. Results of the radiological monitoring program for the calendar year of 1998 continue to indicate that there are no significant releases of radioactive material from Rocketdyne sites. All potential exposure pathways are sampled and/or monitored, including air, soil, surface water, groundwater, and direct radiation. All radioactive wastes are processed for disposal at DOE disposal sites and other sites approved by DOE and licensed for radioactive waste. Liquid radioactive wastes are not released into the environment and do not constitute an exposure pathway

  15. Preliminary evaluation of the Accident Response Mobile Manipulation System for accident site salvage operations

    International Nuclear Information System (INIS)

    Trujillo, J.M.; Morse, W.D.; Jones, D.P.

    1994-01-01

    This paper describes and evaluates operational experiences with the Accident Response Mobile Manipulation System (ARMMS) during simulated accident site salvage operations which might involve nuclear weapons. The ARMMS is based upon a teleoperated mobility platform with two Schilling Titan 7F Manipulators

  16. 0 + 5 Vascular Surgery Residents' Operative Experience in General Surgery: An Analysis of Operative Logs from 12 Integrated Programs.

    Science.gov (United States)

    Smith, Brigitte K; Kang, P Chulhi; McAninch, Chris; Leverson, Glen; Sullivan, Sarah; Mitchell, Erica L

    2016-01-01

    Integrated (0 + 5) vascular surgery (VS) residency programs must include 24 months of training in core general surgery. The Accreditation Council for Graduate Medical Education currently does not require specific case numbers in general surgery for 0 + 5 trainees; however, program directors have structured this time to optimize operative experience. The aim of this study is to determine the case volume and type of cases that VS residents are exposed to during their core surgery training. Accreditation council for graduate medical education operative logs for current 0 + 5 VS residents were obtained and retrospectively reviewed to determine general surgery case volume and distribution between open and laparoscopic cases performed. Standard statistical methods were applied. A total of 12 integrated VS residency programs provided operative case logs for current residents. A total of 41 integrated VS residents in clinical years 2 through 5. During the postgraduate year-1 training year, residents participated in significantly more open than laparoscopic general surgery cases (p surgery cases are hernia repair (20%), skin and soft tissue (7.4%), and breast (6.3%). Residents in programs with core surgery over 3 years participated in significantly more general surgery operations compared with residents in programs with core surgery spread out over 4 years (p = 0.035). 0 + 5 VS residents perform significantly more open operations than laparoscopic operations during their core surgery training. The majority of these operations are minor, nonabdominal procedures. The 0 + 5 VS residency program general surgery operative training requirements should be reevaluated and case minimums defined. The general surgery training component of 0 + 5 VS residencies may need to be restructured to meet the needs of current and future trainees. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  17. Site and stand analysis for growth prediction of Eucalyptus grandis ...

    African Journals Online (AJOL)

    The integration of site information with that of tree growth is of special importance in Zululand, where sustainable supply of timber is essential for local processing and export commitments. Site prediction growth models need to be based on easily attainable input variables that are suitable for operational implementation by ...

  18. Work plan for the remedial investigation/feasibility study-environmental assessment for the quarry residuals operable unit at the Weldon Spring Site

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    The US Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, which is located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis. The Weldon Spring site consists of two noncontiguous areas -- the chemical plant area, which includes four raffinate pits, and the quarry. Cleanup activities at the Weldon Spring site are conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, incorporating the values of the National Environmental Policy Act (NEPA). The contents of the documents prepared for the project are not intended to represent a statement regarding the legal applicability of NEPA to remedial actions conducted under CERCLA. In accordance with the integrated CERCLA/NEPA approach, a remedial investigation/feasibility study-environmental assessment (RI/FS-EA) is being conducted to evaluate conditions and potential responses for the quarry residuals operable unit (QROU). This operable unit consists of the following areas and/or media: the residual material remaining at the Weldon Spring quarry after removal of the pond water and bulk waste; underlying groundwater; and other media located in the surrounding vicinity of the quarry, including adjacent soil, surface water, and sediment in Femme Osage Slough. This work plan identifies the activities within the RI/FS-EA process that are being proposed to address contamination remaining at the quarry area.

  19. Work plan for the remedial investigation/feasibility study-environmental assessment for the quarry residuals operable unit at the Weldon Spring Site

    International Nuclear Information System (INIS)

    1994-01-01

    The US Department of Energy (DOE) is conducting cleanup activities at the Weldon Spring site, which is located in St. Charles County, Missouri, about 48 km (30 mi) west of St. Louis. The Weldon Spring site consists of two noncontiguous areas -- the chemical plant area, which includes four raffinate pits, and the quarry. Cleanup activities at the Weldon Spring site are conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended, incorporating the values of the National Environmental Policy Act (NEPA). The contents of the documents prepared for the project are not intended to represent a statement regarding the legal applicability of NEPA to remedial actions conducted under CERCLA. In accordance with the integrated CERCLA/NEPA approach, a remedial investigation/feasibility study-environmental assessment (RI/FS-EA) is being conducted to evaluate conditions and potential responses for the quarry residuals operable unit (QROU). This operable unit consists of the following areas and/or media: the residual material remaining at the Weldon Spring quarry after removal of the pond water and bulk waste; underlying groundwater; and other media located in the surrounding vicinity of the quarry, including adjacent soil, surface water, and sediment in Femme Osage Slough. This work plan identifies the activities within the RI/FS-EA process that are being proposed to address contamination remaining at the quarry area

  20. Strategic and Operational Benefits of Electronic Integration in B2B Procurement Processes

    OpenAIRE

    Tridas Mukhopadhyay; Sunder Kekre

    2002-01-01

    Our goal is to assess the strategic and operational benefits of electronic integration for industrial procurement. We conduct a field study with an industrial supplier and examine the drivers of performance of the procurement process. Our research quantifies both the operational and strategic impacts of electronic integration in a B2B procurement environment for a supplier. Additionally, we show that the customer also obtains substantial benefits from efficient procurement transaction process...

  1. Rocketdyne Propulsion and Power DOE operations annual site environmental report 1996

    International Nuclear Information System (INIS)

    Tuttle, R.J.

    1997-01-01

    Rocketdyne currently operates several facilities in the San Fernando Valley/Simi Valley area, for manufacturing, testing, and research and development (R and D). These operations include manufacturing liquid-fueled rocket engines, such as the Space Shuttle Main Engine (SSME) and engines used for expendable launch vehicles used to place artificial satellites into orbit. This work includes fabrication and testing of rocket engines, lasers, and heat-transfer systems; and R and D in a wide range of high-technology fields, such as the electrical power system for the Space Station. Previously, this work also included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials, under the Atomics International Division (AI). AI was merged into Rocketdyne in 1984 and many of the AI functions were transferred to existing Rocketdyne departments. This nuclear work was terminated in 1988, and subsequently, all radiological work has been directed toward decontamination and decommissioning (D and D) of the previously used nuclear facilities and associated site areas. The majority of this work is done for the Department of Energy (DOE). This Annual Site Environmental Report for 1996 concentrates on the environmental conditions related to DOE operations at Area IV of SSFL and at De Soto

  2. Probabilistic Steady-State Operation and Interaction Analysis of Integrated Electricity, Gas and Heating Systems

    Directory of Open Access Journals (Sweden)

    Lun Yang

    2018-04-01

    Full Text Available The existing studies on probabilistic steady-state analysis of integrated energy systems (IES are limited to integrated electricity and gas networks or integrated electricity and heating networks. This paper proposes a probabilistic steady-state analysis of integrated electricity, gas and heating networks (EGH-IES. Four typical operation modes of an EGH-IES are presented at first. The probabilistic energy flow problem of the EGS-IES considering its operation modes and correlated uncertainties in wind/solar power and electricity/gas/heat loads is then formulated and solved by the Monte Carlo method based on Latin hypercube sampling and Nataf transformation. Numerical simulations are conducted on a sample EGH-IES working in the “electricity/gas following heat” mode to verify the probabilistic analysis proposed in this paper and to study the effects of uncertainties and correlations on the operation of the EGH-IES, especially uncertainty transmissions among the subnetworks.

  3. Design and operation of a continuous integrated monoclonal antibody production process.

    Science.gov (United States)

    Steinebach, Fabian; Ulmer, Nicole; Wolf, Moritz; Decker, Lara; Schneider, Veronika; Wälchli, Ruben; Karst, Daniel; Souquet, Jonathan; Morbidelli, Massimo

    2017-09-01

    The realization of an end-to-end integrated continuous lab-scale process for monoclonal antibody manufacturing is described. For this, a continuous cultivation with filter-based cell-retention, a continuous two column capture process, a virus inactivation step, a semi-continuous polishing step (twin-column MCSGP), and a batch-wise flow-through polishing step were integrated and operated together. In each unit, the implementation of internal recycle loops allows to improve the performance: (a) in the bioreactor, to simultaneously increase the cell density and volumetric productivity, (b) in the capture process, to achieve improved capacity utilization at high productivity and yield, and (c) in the MCSGP process, to overcome the purity-yield trade-off of classical batch-wise bind-elute polishing steps. Furthermore, the design principles, which allow the direct connection of these steps, some at steady state and some at cyclic steady state, as well as straight-through processing, are discussed. The setup was operated for the continuous production of a commercial monoclonal antibody, resulting in stable operation and uniform product quality over the 17 cycles of the end-to-end integration. The steady-state operation was fully characterized by analyzing at the outlet of each unit at steady state the product titer as well as the process (HCP, DNA, leached Protein A) and product (aggregates, fragments) related impurities. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1303-1313, 2017. © 2017 American Institute of Chemical Engineers.

  4. Formation of Marketing Activity on Organisation and Support of a Corporate Site of Companies That Operate in the Consumer Market

    Directory of Open Access Journals (Sweden)

    Yarym-Agayev Oleksandr M.

    2014-03-01

    Full Text Available The article considers main issues of organisation of Internet marketing at small and medium enterprises of Ukraine, shows a necessity of development and marketing support of the site and provides recommendations on development, implementation and maintenance of corporate sites for marketing and advertising managers. The article considers such directions of operation with the site as analysis of sites of competitors, development of a corporate site, information provision of the site, site indexation and its promotion in search engines, placing site links at information portals, creation of pages in social networks, work at forums, information mailings, operation with site analytics and ensuring feedback with the site visitors. The listed recommendations would allow increase the site image, attract new clients, organise efficient co-operation with specialists on development and promotion of the site and achieve the maximal effect from this source of advertisement and sales.

  5. A resolvase-like protein is requered for the site-specific integration of the temperate lactococcal bacteriophage TP901-1

    DEFF Research Database (Denmark)

    Christiansen, Bettina; Brøndsted, Lone; Vogensen, Finn K.

    1996-01-01

    upstream of attP. The N-terminal 150 to 1180 amino acids of Orf1 showed 38 to 44% similarity to the resolvase group of site-specific integrases, while no similarity to know proteins was found in the C-terminal end. Bacteriophage 'TP901-1 therefore contains a unique integration system that does not resemble...... the Int class of site-specific integrases usually found in temperate bacteriophages. The constructed integration vector, pBC170, integrates into the chromosomal attachment site very efficiently and forms stable transformants with a frequency corresponding to 20% of the transformation efficiency....

  6. A mixed integer linear programming model for integrating thermodynamic cycles for waste heat exploitation in process sites

    International Nuclear Information System (INIS)

    Oluleye, Gbemi; Smith, Robin

    2016-01-01

    Highlights: • MILP model developed for integration of waste heat recovery technologies in process sites. • Five thermodynamic cycles considered for exploitation of industrial waste heat. • Temperature and quantity of multiple waste heat sources considered. • Interactions with the site utility system considered. • Industrial case study presented to illustrate application of the proposed methodology. - Abstract: Thermodynamic cycles such as organic Rankine cycles, absorption chillers, absorption heat pumps, absorption heat transformers, and mechanical heat pumps are able to utilize wasted thermal energy in process sites for the generation of electrical power, chilling and heat at a higher temperature. In this work, a novel systematic framework is presented for optimal integration of these technologies in process sites. The framework is also used to assess the best design approach for integrating waste heat recovery technologies in process sites, i.e. stand-alone integration or a systems-oriented integration. The developed framework allows for: (1) selection of one or more waste heat sources (taking into account the temperatures and thermal energy content), (2) selection of one or more technology options and working fluids, (3) selection of end-uses of recovered energy, (4) exploitation of interactions with the existing site utility system and (5) the potential for heat recovery via heat exchange is also explored. The methodology is applied to an industrial case study. Results indicate a systems-oriented design approach reduces waste heat by 24%; fuel consumption by 54% and CO_2 emissions by 53% with a 2 year payback, and stand-alone design approach reduces waste heat by 12%; fuel consumption by 29% and CO_2 emissions by 20.5% with a 4 year payback. Therefore, benefits from waste heat utilization increase when interactions between the existing site utility system and the waste heat recovery technologies are explored simultaneously. The case study also shows

  7. Integrated Management of all Historical, Operational and Future Decomissioning Solid ILW at Dounreay

    International Nuclear Information System (INIS)

    Graham, D.

    2002-01-01

    This paper describes major components of the Dounreay Site Restoration Plan, DSRP to deal with the site's solid intermediate level waste, ILW legacy. Historic solid ILW exists in the Shaft (disposals between 1959 and 1977), the Wet Silo (operated between 1973 and 1998), and in operating engineered drummed storage. Significant further arisings are expected from future operations, post-operations clean out and decommissioning through to the completion of site restoration, expected to be complete by about 2060. The raw waste is in many solid forms and also incorporates sludge, some fissile material and hazardous chemical components. The aim of the Solid ILW Project is to treat and condition all this waste to make it passively safe and in a form which can be stored for a substantial period, and then transported to the planned U.K. national deep repository for ILW disposal. The Solid ILW Project involves the construction of head works for waste retrieval operations at the Shaft and Wet Silo, a Waste Treatment Plant and a Conditioned Waste Store to hold the conditioned waste until the disposal facilities become available. In addition, there are infrastructure activities to enable the new construction: contaminated ground remediation, existing building demolition, underground and overground services diversion, sea cliff stabilization, and groundwater isolation at the Shaft

  8. Multi-objective design and operation of Solid Oxide Fuel Cell (SOFC) Triple Combined-cycle Power Generation systems: Integrating energy efficiency and operational safety

    International Nuclear Information System (INIS)

    Sharifzadeh, Mahdi; Meghdari, Mojtaba; Rashtchian, Davood

    2017-01-01

    Highlights: • Integrating Solid Oxide Fuel Cells with thermal power plants enhance overall energy efficiency. • However, the high degree of process integration in hybrid power plants limits the operating window. • Multi-objective optimization was applied for integrated design and operation. • The Pareto optimal solutions demonstrated strong trade-off between energy efficiency and operational safety. - Abstract: Energy efficiency is one of the main pathways for energy security and environmental protection. In fact, the International Energy Agency asserts that without energy efficiency, 70% of targeted emission reductions are not achievable. Despite this clarity, enhancing the energy efficiency introduce significant challenge toward process operation. The reason is that the methods applied for energy-saving pose the process operation at the intersection of safety constraints. The present research aims at uncovering the trade-off between safe operation and energy efficiency; an optimization framework is developed that ensures process safety and simultaneously optimizes energy-efficiency, quantified in economic terms. The developed optimization framework is demonstrated for a solid oxide fuel cell (SOFC) power generation system. The significance of this industrial application is that SOFC power plants apply a highly degree of process integration resulting in very narrow operating windows. However, they are subject to significant uncertainties in power demand. The results demonstrate a strong trade-off between the competing objectives. It was observed that highly energy-efficient designs feature a very narrow operating window and limited flexibility. For instance, expanding the safe operating window by 100% will incur almost 47% more annualized costs. Establishing such a trade-off is essential for realizing energy-saving.

  9. Integrated control rod monitoring device

    International Nuclear Information System (INIS)

    Saito, Katsuhiro

    1997-01-01

    The present invention provides a device in which an entire control rod driving time measuring device and a control rod position support device in a reactor building and a central control chamber are integrated systematically to save hardwares such as a signal input/output device and signal cables between boards. Namely, (1) functions of the entire control rod driving time measuring device for monitoring control rods which control the reactor power and a control rod position indication device are integrated into one identical system. Then, the entire devices can be made compact by the integration of the functions. (2) The functions of the entire control rod driving time measuring device and the control rod position indication device are integrated in a central operation board and a board in the site. Then, the place for the installation of them can be used in common in any of the cases. (3) The functions of the entire control rod driving time measuring device and the control rod position indication device are integrated to one identical system to save hardware to be used. Then, signal input/output devices and drift branching panel boards in the site and the central operation board can be saved, and cables for connecting both of the boards is no more necessary. (I.S.)

  10. Site development

    International Nuclear Information System (INIS)

    Gaynor, R.K.

    1989-01-01

    Development of a low-level radioactive waste land disposal facility is little different than any industrial development of similar scope. Consideration must be made for normal business and operations management, security, facility maintenance, traffic control and necessary amenities for personnel. The item specific to the low-level waste site is the handling of radioactive waste materials and the regulatory and environmental protection procedures that must be planned for and accomodated in the site design and development. Each of these elements and the facility as a whole must be designed to be compatible with local land use plans, available transportation and support services, and the social and economic goals of the local community. Plans should also be made for quality control and orderly construction. This chapter deals with those aspects of the facility, its design and construction which are integral parts to the overall performance of the site

  11. Integrated Geophysycal Prospecting in Late Antiquity and Early Medieval Sites in Italy

    Science.gov (United States)

    Giannotta, Maria Teresa; Leucci, Giovanni; De Giorgi, Lara; Matera, Loredana; Persico, Raffaele; Muci, Giuseppe

    2016-04-01

    In this contribution, the results of some integrated geophysical prospecting (magnetometric and GPR) are exposed. This work has been performed in collaboration between archaeologists and geophysicists within the research project "History and Global Archaeology of the Rural Landascapes in Italy, between Late Antiquity and Medieval period. Integrated systems of sources, methodologies, and technologies for a sustainable development", financed by the Italian Ministry for Instruction, University and Research MIUR. In particular, the archaeological sites of Badia and San Giovanni in Malcantone, both in the Apulia Region (eastern-southern Italy) have been prospect. The sites have been identified on the basis of available documents, archaeological surveys and testimonies. In particular, we know that in Badia [1] it was probable the presence of an ancient roman villa of the late ancient period (strongly damaged by the subsequent ploughing activities). Whereas in San Giovanni there is still, today, a small chapel (deconsecrated) that was likely to be part of a previous larger church (probably a basilica of the early Christian period) restricted in the subsequent centuries (probably in more phases). The Saracen raids of the XVI centuries made the site ruined and abandoned. In both sites integrated prospecting have been performed [2-6] with a the integration of archaeological, magnetometer and a GPR data have provided some interesting results, allowing to overcome the difficulties relative to an extensive GPR prospecting, that could not be performed because of the intrinsic superficial roughness and/or the intensive ploughing activities. The prospecting activities, in particular, have added elements that seem to confirm the main archaeological hypothesis that motivate their performing, as it will be show at the conference. References [1] M. T, Giannotta, G. Leucci, R. Persico, M. Leo Imperiale, The archaeological site of Badia in terra d'Otranto: contribution of the

  12. A System-Wide Approach to Physician Efficiency and Utilization Rates for Non-Operating Room Anesthesia Sites.

    Science.gov (United States)

    Tsai, Mitchell H; Huynh, Tinh T; Breidenstein, Max W; O'Donnell, Stephen E; Ehrenfeld, Jesse M; Urman, Richard D

    2017-07-01

    There has been little in the development or application of operating room (OR) management metrics to non-operating room anesthesia (NORA) sites. This is in contrast to the well-developed management framework for the OR management. We hypothesized that by adopting the concept of physician efficiency, we could determine the applicability of this clinical productivity benchmark for physicians providing services for NORA cases at a tertiary care center. We conducted a retrospective data analysis of NORA sites at an academic, rural hospital, including both adult and pediatric patients. Using the time stamps from WiseOR® (Palo Alto, CA), we calculated site utilization and physician efficiency for each day. We defined scheduling efficiency (SE) as the number of staffed anesthesiologists divided by the number of staffed sites and stratified the data into three categories (SE 1). The mean physician efficiency was 0.293 (95% CI, [0.281, 0.305]), and the mean site utilization was 0.328 (95% CI, [0.314, 0.343]). When days were stratified by scheduling efficiency (SE 1), we found differences between physician efficiency and site utilization. On days where scheduling efficiency was less than 1, that is, there are more sites than physicians, mean physician efficiency (95% CI, [0.326, 0.402]) was higher than mean site utilization (95% CI, [0.250, 0.296]). We demonstrate that scheduling efficiency vis-à-vis physician efficiency as an OR management metric diverge when anesthesiologists travel between NORA sites. When the opportunity to scale operational efficiencies is limited, increasing scheduling efficiency by incorporating different NORA sites into a "block" allocation on any given day may be the only suitable tactical alternative.

  13. INTEGRATED ROBOT-HUMAN CONTROL IN MINING OPERATIONS

    Energy Technology Data Exchange (ETDEWEB)

    George Danko

    2005-04-01

    This report contains a detailed description of the work conducted in the first year of the project on Integrated Robot-Human Control in Mining Operations at University of Nevada, Reno. This project combines human operator control with robotic control concepts to create a hybrid control architecture, in which the strengths of each control method are combined to increase machine efficiency and reduce operator fatigue. The kinematics reconfiguration type differential control of the excavator implemented with a variety of ''software machine kinematics'' is the key feature of the project. This software re-configured excavator is more desirable to execute a given digging task. The human operator retains the master control of the main motion parameters, while the computer coordinates the repetitive movement patterns of the machine links. These repetitive movements may be selected from a pre-defined family of trajectories with different transformations. The operator can make adjustments to this pattern in real time, as needed, to accommodate rapidly-changing environmental conditions. A Bobcat{reg_sign} 435 excavator was retrofitted with electro-hydraulic control valve elements. The modular electronic control was tested and the basic valve characteristics were measured for each valve at the Robotics Laboratory at UNR. Position sensors were added to the individual joint control actuators, and the sensors were calibrated. An electronic central control system consisting of a portable computer, converters and electronic driver components was interfaced to the electro-hydraulic valves and position sensors. The machine is operational with or without the computer control system depending on whether the computer interface is on or off. In preparation for emulated mining tasks tests, typical, repetitive tool trajectories during surface mining operations were recorded at the Newmont Mining Corporation's ''Lone Tree'' mine in Nevada.

  14. INTEGRATED SENSOR EVALUATION CIRCUIT AND METHOD FOR OPERATING SAID CIRCUIT

    OpenAIRE

    Krüger, Jens; Gausa, Dominik

    2015-01-01

    WO15090426A1 Sensor evaluation device and method for operating said device Integrated sensor evaluation circuit for evaluating a sensor signal (14) received from a sensor (12), having a first connection (28a) for connection to the sensor and a second connection (28b) for connection to the sensor. The integrated sensor evaluation circuit comprises a configuration data memory (16) for storing configuration data which describe signal properties of a plurality of sensor control signals (26a-c). T...

  15. Remedial investigation/feasibility study work plan for the 100-BC-5 Operable Unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-04-01

    Four areas of the Hanford Site (the 100, 200, 300 and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Figure 1-1 shows the location of these areas. Under the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1990a), signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1,000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste and other CERCLA hazardous substances. Also included in the Tri-Party Agreement are 55 Resource Conservation and Recovery Act (RCRA) treatment, storage, or disposal (TSD) facilities that will be closed or permitted to operate in accordance with RCRA regulations, under the authority of Chapter 173-303 Washington Administrative Code (WAC). Some of the TSD facilities are included in the operable units. This work plant and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-BC-5 operable unit. The 100-B/C Area consists of the 100-BC-5 groundwater operable unit and four source operable units. The 100-BC-5 operable unit includes all contamination found in the aquifer soils and water beneath the 100-B/C Area. Source operable units include facilities and unplanned release sites that are potential sources of contamination

  16. Effects of site management operations on the nutrient capital of a ...

    African Journals Online (AJOL)

    The Karkloof Project is a case study of the effects of intensive site management operations during the interrotational period, on (a) the nutrient capital of the system, and (b) the availability of growth resources (nutrients and water) in a commercial Eucalyptus grandis stand in South Africa. This paper specifically focuses on the ...

  17. New integral representations of the Maslov canonical operator in singular charts

    Science.gov (United States)

    Dobrokhotov, S. Yu.; Nazaikinskii, V. E.; Shafarevich, A. I.

    2017-04-01

    We construct a new integral representation of the Maslov canonical operator convenient in numerical-analytical calculations, present an algorithm implementing this representation, and consider a number of examples.

  18. The importance of flexible power plant operation for Jiangsu's wind integration

    DEFF Research Database (Denmark)

    Hong, Lixuan; Lund, Henrik; Möller, Bernd

    2012-01-01

    This paper presents the influence of different regulation strategies on wind energy integration into the existing energy system of Jiangsu. The ability of wind integration is defined in terms of the ability to avoid excess electricity production, to conserve primary energy consumption and to redu...... regulations of Jiangsu’s energy system are compared and analyzed in the range of a wind input from 0% to 42% of the total electricity demand. It is concluded that operating power plants in a flexible way facilitates the promotion of more intermittent wind integration....

  19. Bidirectional Retroviral Integration Site PCR Methodology and Quantitative Data Analysis Workflow.

    Science.gov (United States)

    Suryawanshi, Gajendra W; Xu, Song; Xie, Yiming; Chou, Tom; Kim, Namshin; Chen, Irvin S Y; Kim, Sanggu

    2017-06-14

    Integration Site (IS) assays are a critical component of the study of retroviral integration sites and their biological significance. In recent retroviral gene therapy studies, IS assays, in combination with next-generation sequencing, have been used as a cell-tracking tool to characterize clonal stem cell populations sharing the same IS. For the accurate comparison of repopulating stem cell clones within and across different samples, the detection sensitivity, data reproducibility, and high-throughput capacity of the assay are among the most important assay qualities. This work provides a detailed protocol and data analysis workflow for bidirectional IS analysis. The bidirectional assay can simultaneously sequence both upstream and downstream vector-host junctions. Compared to conventional unidirectional IS sequencing approaches, the bidirectional approach significantly improves IS detection rates and the characterization of integration events at both ends of the target DNA. The data analysis pipeline described here accurately identifies and enumerates identical IS sequences through multiple steps of comparison that map IS sequences onto the reference genome and determine sequencing errors. Using an optimized assay procedure, we have recently published the detailed repopulation patterns of thousands of Hematopoietic Stem Cell (HSC) clones following transplant in rhesus macaques, demonstrating for the first time the precise time point of HSC repopulation and the functional heterogeneity of HSCs in the primate system. The following protocol describes the step-by-step experimental procedure and data analysis workflow that accurately identifies and quantifies identical IS sequences.

  20. Pre-Operative Skin Antisepsis with Chlorhexidine Gluconate and Povidone-Iodine to Prevent Port-Site Infection in Laparoscopic Cholecystectomy: A Prospective Study.

    Science.gov (United States)

    Spaziani, Erasmo; Di Filippo, Annalisa; Orelli, Simone; Fiorini, Flavia; Spaziani, Martina; Tintisona, Orlando; Torcasio, Angelo; De Cesare, Alessandro; Picchio, Marcello

    2018-04-01

    Skin preparation with antiseptic agents is commonly recommended for incisional site cleansing before surgery. We present the result of a prospective case series submitted to a scheduled pre-operative antiseptic procedure combining chlorhexidine gluconate and povidone-iodine before elective laparoscopic cholecystectomy. Consecutive patients underwent pre-operative standardized cleansing of the operation site combining chlorhexidine gluconate and povidone-iodine. Patients were reviewed one week and four weeks post-operatively. Post-operative infection was observed in seven patients (4.3%). All observed infections were port-site infections, always located at the level of the umbilical incision. In all cases infections involved skin and subcutaneous tissue. Staphylococcus aureus was isolated in five patients (71.4%) and miscellaneous aerobic gram-positive bacteria in two subjects (28.6%). Post-operative hospital stay was the only factor significantly associated with the development of port-site infections. Port-site infections are a common complication after elective laparoscopic cholecystectomy. The proposed pre-operative disinfection procedure is effective in reducing port-site infections. Reducing hospital stay may contribute to limiting the occurrence of this complication.

  1. Integrating wind output with bulk power operations and wholesale electricity markets

    International Nuclear Information System (INIS)

    Hirst, E.

    2002-01-01

    Wind farms have three characteristics that complicate their widespread application as an electricity resource: limited control, unpredictability and variability. Therefore the integration of wind output into bulk power electric systems is qualitatively different from that of other types of generators. The electric system operator must move other generators up or down to offset the time-varying wind fluctuations. Such movements raise the costs of fuel and maintenance for these other generators. Not only is wind power different, it is new. The operators of bulk power systems have limited experience in integrating wind output into the larger system. As a consequence, market rules that treat wind fairly - neither subsidizing nor penalizing its operation - have not yet been developed. The lack of data and analytical methods encourages wind advocates and sceptics to rely primarily on their biases and beliefs in suggesting how wind should be integrated into bulk power systems. This project helps fill this data and analysis gap. Specifically, it develops and applies a quantitative method for the integration of a wind resource into a large electric system. The method permits wind to bid its output into a short-term forward market (specifically, an hour-ahead energy market) or to appear in real time and accept only intrahour and hourly imbalance payments for the unscheduled energy it delivers to the system. Finally, the method analyses the short-term (minute-to-minute) variation in wind output to determine the regulation requirement the wind resource imposes on the electrical system. (author)

  2. Commercial integration and partnering at Savannah River Site

    Energy Technology Data Exchange (ETDEWEB)

    Steele, J.R. [Westinghouse Savannah River Co., Aiken, SC (United States); Babione, R.A.; Shikashio, L.A.; Wacaster, A.J.; Paterson, A.D. [SCIENTECH, Inc., Idaho Falls, ID (United States)

    1994-06-01

    Savannah River Site (SRS), particularly the Savannah River Technology Center (SRTC) with the experience from the first successful Integrated Technology Demonstration, can provide an excellent foundation for meeting DOE-EM`s objectives with the new DOE-EM five focus area approach. With this in mind, SRTC established an activity to pursue full commercialization of environmental technologies. This report is an assessment of the status of commercialization at SRS and provides recommendations for enhancement as well as some tools critical to implementation. A review was made of the current situation at SRS with regards to taking technology development to commercial fruition. This was done from the perspective of comparing it to known commercialization models and processes. It was found that SRTC already works through many of the steps in these processes. With integration and action-oriented efforts of the inclusion of business and market factors, SRTC could become an aggressive, successful developer of commercialized technologies. Commercial success criteria tools were developed with regards to integrating them with SRTC selection criteria to ensure that all critical factors are covered in technology commercialization project evaluations. Private investors are very clear that their interest lies in funding commercial enterprises, not merely technologies. Mobilizing private capital is critical to real job growth and long-term economic development. Also, potential industry partners were identified that are willing to be involved with SRS` technology applications and regional development efforts. As another important component to success, regional support organizations were reviewed and evaluated.

  3. How to Commission, Operate and Maintain a Large Future Accelerator Complex From Far Remote Sites

    International Nuclear Information System (INIS)

    Phinney, Nan

    2001-01-01

    A study on future large accelerators [1] has considered a facility, which is designed, built and operated by a worldwide collaboration of equal partner institutions, and which is remote from most of these institutions. The full range of operation was considered including commissioning, machine development, maintenance, trouble shooting and repair. Experience from existing accelerators confirms that most of these activities are already performed remotely. The large high-energy physics experiments and astronomy projects, already involve international collaborations of distant institutions. Based on this experience, the prospects for a machine operated remotely from far sites are encouraging. Experts from each laboratory would remain at their home institution but continue to participate in the operation of the machine after construction. Experts are required to be on site only during initial commissioning and for particularly difficult problems. Repairs require an on-site non-expert maintenance crew. Most of the interventions can be made without an expert and many of the rest resolved with remote assistance. There appears to be no technical obstacle to controlling an accelerator from a distance. The major challenge is to solve the complex management and communication problems

  4. How to Commission, Operate and Maintain a Large Future Accelerator Complex From Far Remote Sites

    Energy Technology Data Exchange (ETDEWEB)

    Phinney, Nan

    2001-12-07

    A study on future large accelerators [1] has considered a facility, which is designed, built and operated by a worldwide collaboration of equal partner institutions, and which is remote from most of these institutions. The full range of operation was considered including commissioning, machine development, maintenance, troubleshooting and repair. Experience from existing accelerators confirms that most of these activities are already performed 'remotely'. The large high-energy physics experiments and astronomy projects, already involve international collaborations of distant institutions. Based on this experience, the prospects for a machine operated remotely from far sites are encouraging. Experts from each laboratory would remain at their home institution but continue to participate in the operation of the machine after construction. Experts are required to be on site only during initial commissioning and for particularly difficult problems. Repairs require an on-site non-expert maintenance crew. Most of the interventions can be made without an expert and many of the rest resolved with remote assistance. There appears to be no technical obstacle to controlling an accelerator from a distance. The major challenge is to solve the complex management and communication problems.

  5. Utilizing the fluidized bed to initiate water treatment on site

    International Nuclear Information System (INIS)

    Ahmadvand, H.; Germann, G.; Gandee, J.P.; Buehler, V.T.

    1995-01-01

    Escalating wastewater disposal costs coupled with enforcement of stricter regulations push industrial sites previously without water treatment to treat on site. These sites, inexperienced in water treatment, require a treatment technology that is easily installed, operated, and maintained. The aerobic granular activated carbon (GAC) fluidized bed incorporates biological and adsorptive technologies into a simple, cost-effective process capable of meeting strict effluent requirements. Two case studies at industrial sites illustrate the installation and operation of the fluidized bed and emphasize the ability to use the fluidized bed singularly or as an integral component of a treatment system capable of achieving treatment levels that allow surface discharge and reinjection. Attention is focused on BTEX (benzene, toluene, ethylbenzene, and xylenes)

  6. CEO Sites Mission Management System (SMMS)

    Science.gov (United States)

    Trenchard, Mike

    2014-01-01

    Late in fiscal year 2011, the Crew Earth Observations (CEO) team was tasked to upgrade its science site database management tool, which at the time was integrated with the Automated Mission Planning System (AMPS) originally developed for Earth Observations mission planning in the 1980s. Although AMPS had been adapted and was reliably used by CEO for International Space Station (ISS) payload operations support, the database structure was dated, and the compiler required for modifications would not be supported in the Windows 7 64-bit operating system scheduled for implementation the following year. The Sites Mission Management System (SMMS) is now the tool used by CEO to manage a heritage Structured Query Language (SQL) database of more than 2,000 records for Earth science sites. SMMS is a carefully designed and crafted in-house software package with complete and detailed help files available for the user and meticulous internal documentation for future modifications. It was delivered in February 2012 for test and evaluation. Following acceptance, it was implemented for CEO mission operations support in April 2012. The database spans the period from the earliest systematic requests for astronaut photography during the shuttle era to current ISS mission support of the CEO science payload. Besides logging basic image information (site names, locations, broad application categories, and mission requests), the upgraded database management tool now tracks dates of creation, modification, and activation; imagery acquired in response to requests; the status and location of ancillary site information; and affiliations with studies, their sponsors, and collaborators. SMMS was designed to facilitate overall mission planning in terms of site selection and activation and provide the necessary site parameters for the Satellite Tool Kit (STK) Integrated Message Production List Editor (SIMPLE), which is used by CEO operations to perform daily ISS mission planning. The CEO team

  7. Remedial investigation/feasibility study work plan for the 100-KR-1 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-07-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Figure 1-1 shows the location of these areas. Under the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1990a), signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1,000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste, and other CERCLA hazardous substances. Also included in the Tri-Party Agreement are 55 Resource Conservation and Recovery Act (RCRA) treatment, storage, or disposal (TSD) facilities that will be closed or permitted to operate in accordance with RCRA regulations, under the authority of Chapter 173-303 Washington Administrative Code (WAC). Some of the TSD facilities are included in the operable units. This work plan and the attached supporting project plans establish the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-KR-1 operable unit. The 100-KR-1 source operable unit is one of three source operable units in the 100-K Area. Source operable units include facilities and unplanned release sites that are potential sources of hazardous substance contamination

  8. 36 CFR 6.5 - Solid waste disposal sites in operation on September 1, 1984.

    Science.gov (United States)

    2010-07-01

    ... Insecticide, Fungicide and Rodenticide Act (7 U.S.C. 136 et seq.); (vi) Sludge from a waste treatment plant... leased by the operator; and (iii) the solid waste disposal site lacks road, rail, or adequate water... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Solid waste disposal sites in...

  9. Different integrated geophysical approaches to investigate archaeological sites in urban and suburban area.

    Science.gov (United States)

    Piro, Salvatore; Papale, Enrico; Zamuner, Daniela

    2016-04-01

    Geophysical methods are frequently used in archaeological prospection in order to provide detailed information about the presence of structures in the subsurface as well as their position and their geometrical reconstruction, by measuring variations of some physical properties. Often, due to the limited size and depth of an archaeological structure, it may be rather difficult to single out its position and extent because of the generally low signal-to-noise ratio. This problem can be overcome by improving data acquisition, processing techniques and by integrating different geophysical methods. In this work, two sites of archaeological interest, were investigated employing several methods (Ground Penetrating Radar (GPR), Electrical Resistivity Tomography (ERT), Fluxgate Differential Magnetic) to obtain precise and detailed maps of subsurface bodies. The first site, situated in a suburban area between Itri and Fondi, in the Aurunci Natural Regional Park (Central Italy), is characterized by the presence of remains of past human activity dating from the third century B.C. The second site, is instead situated in an urban area in the city of Rome (Basilica di Santa Balbina), where historical evidence is also present. The methods employed, allowed to determine the position and the geometry of some structures in the subsurface related to this past human activity. To have a better understanding of the subsurface, we then performed a qualitative and quantitative integration of this data, which consists in fusing the data from all the methods used, to have a complete visualization of the investigated area. Qualitative integration consists in graphically overlaying the maps obtained by the single methods; this method yields only images, not new data that may be subsequently analyzed. Quantitative integration is instead performed by mathematical and statistical solutions, which allows to have a more accurate reconstruction of the subsurface and generates new data with high

  10. Integrated Emission Management strategy for cost-optimal engine-aftertreatment operation

    NARCIS (Netherlands)

    Cloudt, R.P.M.; Willems, F.P.T.

    2011-01-01

    A new cost-based control strategy is presented that optimizes engine-aftertreatment performance under all operating conditions. This Integrated Emission Management strategy minimizes fuel consumption within the set emission limits by on-line adjustment of air management based on the actual state of

  11. Financial services FY 1995 site support program plan WBS 6.10.4

    Energy Technology Data Exchange (ETDEWEB)

    Vodney, E.P.

    1994-09-01

    This is the signed Financial Service fiscal year 1995 Site Support Program Plan, Work Breakdown Structure 6.10.4, for the Hanford site. This plan is intended to enable the contractor to accomplish the following: ensure financial integrity in all Westinghouse Hanford Company (WHC) operation while supporting the programmatic activities of WHC, the US Department of Energy, Richland Operations Office, and other Hanford contractors; provide efficient and effective financial services, and value added audits and review that enable management to enhance future operational results.

  12. Industrial hygiene support of underground operations at the Nevada Test Site

    International Nuclear Information System (INIS)

    Porter, P.F.

    1992-01-01

    The Industrial Hygiene Section of the Health Protection Department provides industrial hygiene support of underground operations at the Nevada Test Site. This report describes support operations and summarizes the industrial hygiene data collected from July 31, 1989 through June 30, 1991. Air quality data were collected by means of personnel sampling by active and passive techniques using various kinds of industrial hygiene instrumentation and through localized and general area monitoring. The data collected were used to evaluate underground air quality and quantity requirements; evaluate worker exposures to a variety of air contaminants; determine the applicability and effectiveness of personal protective equipment

  13. Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus.

    Directory of Open Access Journals (Sweden)

    Sanggu Kim

    Full Text Available Xenotropic murine leukemia virus (MLV-related virus (XMRV is a new human retrovirus associated with prostate cancer and chronic fatigue syndrome. The causal relationship of XMRV infection to human disease and the mechanism of pathogenicity have not been established. During retrovirus replication, integration of the cDNA copy of the viral RNA genome into the host cell chromosome is an essential step and involves coordinated joining of the two ends of the linear viral DNA into staggered sites on target DNA. Correct integration produces proviruses that are flanked by a short direct repeat, which varies from 4 to 6 bp among the retroviruses but is invariant for each particular retrovirus. Uncoordinated joining of the two viral DNA ends into target DNA can cause insertions, deletions, or other genomic alterations at the integration site. To determine the fidelity of XMRV integration, cells infected with XMRV were clonally expanded and DNA sequences at the viral-host DNA junctions were determined and analyzed. We found that a majority of the provirus ends were correctly processed and flanked by a 4-bp direct repeat of host DNA. A weak consensus sequence was also detected at the XMRV integration sites. We conclude that integration of XMRV DNA involves a coordinated joining of two viral DNA ends that are spaced 4 bp apart on the target DNA and proceeds with high fidelity.

  14. Operational facility-integrated computer system for safeguards

    International Nuclear Information System (INIS)

    Armento, W.J.; Brooksbank, R.E.; Krichinsky, A.M.

    1980-01-01

    A computer system for safeguards in an active, remotely operated, nuclear fuel processing pilot plant has been developed. This sytem maintains (1) comprehensive records of special nuclear materials, (2) automatically updated book inventory files, (3) material transfer catalogs, (4) timely inventory estimations, (5) sample transactions, (6) automatic, on-line volume balances and alarmings, and (7) terminal access and applications software monitoring and logging. Future development will include near-real-time SNM mass balancing as both a static, in-tank summation and a dynamic, in-line determination. It is planned to incorporate aspects of site security and physical protection into the computer monitoring

  15. 49 CFR 192.909 - How can an operator change its integrity management program?

    Science.gov (United States)

    2010-10-01

    ... (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.909 How can an operator change its integrity management...

  16. Integrating Space Systems Operations at the Marine Expeditionary Force Level

    Science.gov (United States)

    2015-06-01

    Operation ARSST Army Space Support Team BCT Brigade Combat Team BDA Battle Damage Assessment BLOS Beyond Line of Site C2 Command and Control CMCC-CP...accurate imagery of known target locations. Additionally, ISR systems provide a convenient battle damage assessment ( BDA ) option necessary to determine

  17. New design for photonic temporal integration with combined high processing speed and long operation time window.

    Science.gov (United States)

    Asghari, Mohammad H; Park, Yongwoo; Azaña, José

    2011-01-17

    We propose and experimentally prove a novel design for implementing photonic temporal integrators simultaneously offering a high processing bandwidth and a long operation time window, namely a large time-bandwidth product. The proposed scheme is based on concatenating in series a time-limited ultrafast photonic temporal integrator, e.g. implemented using a fiber Bragg grating (FBG), with a discrete-time (bandwidth limited) optical integrator, e.g. implemented using an optical resonant cavity. This design combines the advantages of these two previously demonstrated photonic integrator solutions, providing a processing speed as high as that of the time-limited ultrafast integrator and an operation time window fixed by the discrete-time integrator. Proof-of-concept experiments are reported using a uniform fiber Bragg grating (as the original time-limited integrator) connected in series with a bulk-optics coherent interferometers' system (as a passive 4-points discrete-time photonic temporal integrator). Using this setup, we demonstrate accurate temporal integration of complex-field optical signals with time-features as fast as ~6 ps, only limited by the processing bandwidth of the FBG integrator, over time durations as long as ~200 ps, which represents a 4-fold improvement over the operation time window (~50 ps) of the original FBG integrator.

  18. Integrated operation of electric vehicles and renewable generation in a smart distribution system

    International Nuclear Information System (INIS)

    Zakariazadeh, Alireza; Jadid, Shahram; Siano, Pierluigi

    2015-01-01

    Highlights: • The contribution of electric vehicles to provide the reserve capacity is analyzed. • Decentralized energy and reserve scheduling in a distribution system is presented. • The integrated operation of renewable generation and electric vehicles is proposed. - Abstract: Distribution system complexity is increasing mainly due to technological innovation, renewable Distributed Generation (DG) and responsive loads. This complexity makes difficult the monitoring, control and operation of distribution networks for Distribution System Operators (DSOs). In order to cope with this complexity, a novel method for the integrated operational planning of a distribution system is presented in this paper. The method introduces the figure of the aggregator, conceived as an intermediate agent between end-users and DSOs. In the proposed method, energy and reserve scheduling is carried out by both aggregators and DSO. Moreover, Electric Vehicles (EVs) are considered as responsive loads that can participate in ancillary service programs by providing reserve to the system. The efficiency of the proposed method is evaluated on an 84-bus distribution test system. Simulation results show that the integrated scheduling of EVs and renewable generators can mitigate the negative effects related to the uncertainty of renewable generation

  19. Operational radioactive defense waste management plan for the Nevada Test Site

    International Nuclear Information System (INIS)

    1981-07-01

    The Operational Radioactive Defense Waste Management Plan for the Nevada Test Site establishes procedures and methods for the safe shipping, receiving, processing, disposal, and storage of radioactive waste. Included are NTS radioactive waste disposition program guidelines, procedures for radioactive waste management, a description of storage and disposal areas and facilities, and a glossary of specifications and requirements

  20. Integrated approach to optimize operation and maintenance costs for operating nuclear power plants

    International Nuclear Information System (INIS)

    2006-06-01

    In the context of increasingly open electricity markets and the 'unbundling' of generating companies from former utility monopolies, an area of major concern is the economic performance of the existing fleet of nuclear power plants. Nuclear power, inevitably, must compete directly with other electricity generation sources. Coping with this competitive pressure is a challenge that the nuclear industry should meet if the nuclear option is to remain a viable one. This competitive environment has significant implications for nuclear plant operations, including, among others, the need for the more cost effective management of plant activities, and the greater use of analytical tools to balance the costs and benefits of proposed activities, in order to optimize operation and maintenance costs, and thus insure the economic competitiveness of existing nuclear power plants. In the framework of the activities on Nuclear Economic Performance Information System (NEPIS), the IAEA embarked in developing guidance on optimization of operation and maintenance costs for nuclear power plants. The report was prepared building on the fundamental that optimization of operation and maintenance costs of a nuclear power plant is a key component of a broader integrated business strategic planning process, having as overall result achievement of organization's business objectives. It provides advice on optimization of O and M costs in the framework of strategic business planning, with additional details on operational planning and controlling. This TECDOC was elaborated in 2004-2005 in the framework of the IAEA's programme on Nuclear Power Plant Operating Performance and Life Cycle Management, with the support of two consultants meetings and one technical meeting and based on contributions provided by participants. It can serve as a useful reference for the management and operation staff within utilities, nuclear power plant operators and regulators and other organizations involved in

  1. The Mixed Waste Management Facility. Design basis integrated operations plan (Title I design)

    International Nuclear Information System (INIS)

    1994-12-01

    The Mixed Waste Management Facility (MWMF) will be a fully integrated, pilotscale facility for the demonstration of low-level, organic-matrix mixed waste treatment technologies. It will provide the bridge from bench-scale demonstrated technologies to the deployment and operation of full-scale treatment facilities. The MWMF is a key element in reducing the risk in deployment of effective and environmentally acceptable treatment processes for organic mixed-waste streams. The MWMF will provide the engineering test data, formal evaluation, and operating experience that will be required for these demonstration systems to become accepted by EPA and deployable in waste treatment facilities. The deployment will also demonstrate how to approach the permitting process with the regulatory agencies and how to operate and maintain the processes in a safe manner. This document describes, at a high level, how the facility will be designed and operated to achieve this mission. It frequently refers the reader to additional documentation that provides more detail in specific areas. Effective evaluation of a technology consists of a variety of informal and formal demonstrations involving individual technology systems or subsystems, integrated technology system combinations, or complete integrated treatment trains. Informal demonstrations will typically be used to gather general operating information and to establish a basis for development of formal demonstration plans. Formal demonstrations consist of a specific series of tests that are used to rigorously demonstrate the operation or performance of a specific system configuration

  2. Site suitability evaluation of an old operating landfill using AHP and GIS techniques and integrated hydrogeological and geophysical surveys.

    Science.gov (United States)

    Saatsaz, Masoud; Monsef, Iman; Rahmani, Mostafa; Ghods, Abdolreza

    2018-02-16

    Because of the outdated methods of common landfill selection, it is imperative to reevaluate the usage suitability. To assess the suitability of the existing waste landfill in Zanjan, Iran, we have used a combination of the analytical hierarchy process (AHP) and GIS techniques, along with fieldwork surveys. Four major criteria and 12 subcriteria were considered, and the AHP was applied to assign the relative importance weights of criteria and subcriteria to each other. Finally, a landfill suitability map was generated and ranked based on the final suitability scores. The results show that the unsuitable areas are around Zanjan, in the middle parts of the plain. By contrast, the most suitable areas are uncultivated areas, located mostly in the west, north, and south. The results also indicate that the present landfill is a highly suitable site. After desk studies, geoelectrical surveys and infiltration measurements were conducted to make the final decision. Double-ring permeability tests confirm the landfill is an acceptable site. The electrical sounding shows that the leachate plume has a width of about ~ 450 m, spreads to a depth of about ~ 55 m, and migrates towards the northeast. Considering the groundwater depth, dry climate, and a low infiltration rate of the landfill soils, it can be concluded that leachate plumes will not contaminate groundwater within this decade. The proposed method can be implemented to reevaluate the suitability of any old operating reservoir such as oil reservoirs, petrol filling stations, heavy industrial tanks, and landfills, containing liquid hazardous materials.

  3. Final environmental assessment for off-site transportation of low-level waste from four California sites under the management of the U.S. Department of Energy Oakland Operations Office

    International Nuclear Information System (INIS)

    1997-10-01

    The Department of Energy Oakland Operations Office (DOE/OAK) manages sites within California that generate Low Level Waste (LLW) in the course or routine site operations. It is the preference of the DOE to dispose of LLW at federally owned and DOE-operated disposal facilities; however, in some circumstances DOE Headquarters has determined that disposal at commercial facilities is appropriate, as long as the facility meets all regulatory requirements for the acceptance and disposal of LLW, including the passage of a DOE audit to determine the adequacy of the disposal site. The DOE would like to ship LLW from four DOE/OAK sites in California which generate LLW, to NRC-licensed commercial nuclear waste disposal facilities such as Envirocare in Clive, Utah and Chem Nuclear in Barnwell, South Carolina. Transportation impacts for shipment of LLW and MLLW from DOE Oakland sites to other DOE sites was included in the impacts identified in the Department's Waste Management Programmatic Environmental Impact Statement (WM-PEIS), published in May, 1997, and determined to be low. The low impacts for shipment to commercial sites identified herein is consistent with the WM-PEIS results

  4. Advanced, Integrated Control for Building Operations to Achieve 40% Energy Saving

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Yan; Song, Zhen; Loftness, Vivian; Ji, Kun; Zheng, Sam; Lasternas, Bertrand; Marion, Flore; Yuebin, Yu

    2012-10-15

    We developed and demonstrated a software based integrated advanced building control platform called Smart Energy Box (SEB), which can coordinate building subsystem controls, integrate variety of energy optimization algorithms and provide proactive and collaborative energy management and control for building operations using weather and occupancy information. The integrated control system is a low cost solution and also features: Scalable component based architecture allows to build a solution for different building control system configurations with needed components; Open Architecture with a central data repository for data exchange among runtime components; Extendible to accommodate variety of communication protocols. Optimal building control for central loads, distributed loads and onsite energy resource; uses web server as a loosely coupled way to engage both building operators and building occupants in collaboration for energy conservation. Based on the open platform of SEB, we have investigated and evaluated a variety of operation and energy saving control strategies on Carnegie Mellon University Intelligent Work place which is equipped with alternative cooling/heating/ventilation/lighting methods, including radiant mullions, radiant cooling/heating ceiling panels, cool waves, dedicated ventilation unit, motorized window and blinds, and external louvers. Based on the validation results of these control strategies, they were integrated in SEB in a collaborative and dynamic way. This advanced control system was programmed and computer tested with a model of the Intelligent Workplace's northern section (IWn). The advanced control program was then installed in the IWn control system; the performance was measured and compared with that of the state of the art control system to verify the overall energy savings great than 40%. In addition advanced human machine interfaces (HMI's) were developed to communicate both with building

  5. Sizewell integrated system for centralized operations: getting it all together

    International Nuclear Information System (INIS)

    Cook, B.M.; Robinson, D.E.P.

    1992-01-01

    In June 1991, Westinghouse was awarded a contract by Nuclear Electric to supply the Integrated System for Centralized Operations (ISCO) for the Sizewell B nuclear power plant under construction in Suffolk. This system is a large scale distributed control and instrumentation system that will perform safety and control functions for the primary and secondary systems for the plant. Combined with the control and instrumentation equipment that was already being supplied for the plant by Westinghouse, this will be the most extensive integration of modern digital control equipment on a nuclear power plant to date. The ISCO architecture, consisting of 3 major segments -high integrity control, process control and the distributed computer system - is described. The history of the ISCO development is explained. (Author)

  6. Integration of computerized operation support systems on a nuclear power plant environment

    Energy Technology Data Exchange (ETDEWEB)

    Jaime, Guilherme D.G.; Almeida, Jose C.S.; Oliveira, Mauro V., E-mail: gdjaime@ien.gov.br, E-mail: jcsa@ien.gov.br, E-mail: mvitor@ien.gov.br [Instituto Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Servico de Sistemas Complexos. Divisao de Engenharia Nuclear

    2015-07-01

    Automation of certain tasks in a Nuclear Power Plant (NPP) control room is expected to result in reduced operators' mental workload, which may induce other benefits such as enhanced situation awareness and improved system performance. The final goal should be higher level of operational safety. Thus, recent works are increasingly assessing automation. The LABIHS compact NPP simulator, though, still operates under strictly manual printed hard-copy procedures, despite of the fact that the simulator incorporates several advancements in design of digitalized Human-Interfaces (HSIs). This work presents the development, implementation and integration of selected components to achieve increased level of computerized/automated operation of the LABIHS compact NPP simulator. Specifically, we discuss three components: (I) Automatic Plant Mode Detection, (II) Automatic Alarm Filtering, and (III) Computerized Procedures. Each one of these components has to be carefully designed/integrated so that one can avoid the undesired effects of some known implementations of automated systems on NPP, such as the reduction in the operator's system awareness, an increase in monitoring workload, and the degradation in manual skills, which could lead to automation-induced system failures. (author)

  7. Integration of computerized operation support systems on a nuclear power plant environment

    International Nuclear Information System (INIS)

    Jaime, Guilherme D.G.; Almeida, Jose C.S.; Oliveira, Mauro V.

    2015-01-01

    Automation of certain tasks in a Nuclear Power Plant (NPP) control room is expected to result in reduced operators' mental workload, which may induce other benefits such as enhanced situation awareness and improved system performance. The final goal should be higher level of operational safety. Thus, recent works are increasingly assessing automation. The LABIHS compact NPP simulator, though, still operates under strictly manual printed hard-copy procedures, despite of the fact that the simulator incorporates several advancements in design of digitalized Human-Interfaces (HSIs). This work presents the development, implementation and integration of selected components to achieve increased level of computerized/automated operation of the LABIHS compact NPP simulator. Specifically, we discuss three components: (I) Automatic Plant Mode Detection, (II) Automatic Alarm Filtering, and (III) Computerized Procedures. Each one of these components has to be carefully designed/integrated so that one can avoid the undesired effects of some known implementations of automated systems on NPP, such as the reduction in the operator's system awareness, an increase in monitoring workload, and the degradation in manual skills, which could lead to automation-induced system failures. (author)

  8. SARDA: An Integrated Concept for Airport Surface Operations Management

    Science.gov (United States)

    Gupta, Gautam; Hoang, Ty; Jung, Yoon Chul

    2013-01-01

    The Spot and Runway Departure Advisor (SARDA) is an integrated decision support tool for airlines and air traffic control tower enabling surface collaborative decision making (CDM) and departure metering in order to enhance efficiency of surface operations at congested airports. The presentation describes the concept and architecture of the SARDA as a CDM tool, and the results from a human-in-the-loop simulation of the tool conducted in 2012 at the FutureFlight Central, the tower simulation facility. Also, presented is the current activities and future plan for SARDA development. The presentation was given at the meeting with the FAA senior advisor of the Surface Operations Office.

  9. Integrating cost management and work management concepts for operations

    International Nuclear Information System (INIS)

    Vanditmars, C.

    1995-01-01

    Development of B C Gas Utility Limited's integrated work and cost management system was described, with emphasis on cost management without reliance on the financial systems, and standard costing and operational side benefits. The objectives of the system were identified as dynamic monitoring and control, and local empowerment. The concept underlying the two systems was explained in detail. In the case of the work management system the ability to manage all work in operations areas was stressed, along with its universal availability. Other benefits expected included improved resource utilization, improved productivity, better control of cost, improved revenue generation, superior customer service, a simplified financial system, and improved employee motivation through empowerment

  10. Remedial investigation/feasibility study work plan for the 100-KR-4 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-KR-4 operable unit. The 100-K Area consists of the 100-KR-4 groundwater operable unit and three source operable units. The 100-KR-4 operable unit includes all contamination found in the aquifer soils and water beneath the 100-K Area. Source operable units include facilities and unplanned release sites that are potential sources of contamination

  11. Remedial investigation/feasibility study work plan for the 100-KR-4 operable unit, Hanford Site, Richland, Washington

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency`s (EPA`s) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the CERCLA remedial investigation/feasibility study (RI/FS) for the 100-KR-4 operable unit. The 100-K Area consists of the 100-KR-4 groundwater operable unit and three source operable units. The 100-KR-4 operable unit includes all contamination found in the aquifer soils and water beneath the 100-K Area. Source operable units include facilities and unplanned release sites that are potential sources of contamination.

  12. An integrated CRISPR Bombyx mori genome editing system with improved efficiency and expanded target sites.

    Science.gov (United States)

    Ma, Sanyuan; Liu, Yue; Liu, Yuanyuan; Chang, Jiasong; Zhang, Tong; Wang, Xiaogang; Shi, Run; Lu, Wei; Xia, Xiaojuan; Zhao, Ping; Xia, Qingyou

    2017-04-01

    Genome editing enabled unprecedented new opportunities for targeted genomic engineering of a wide variety of organisms ranging from microbes, plants, animals and even human embryos. The serial establishing and rapid applications of genome editing tools significantly accelerated Bombyx mori (B. mori) research during the past years. However, the only CRISPR system in B. mori was the commonly used SpCas9, which only recognize target sites containing NGG PAM sequence. In the present study, we first improve the efficiency of our previous established SpCas9 system by 3.5 folds. The improved high efficiency was also observed at several loci in both BmNs cells and B. mori embryos. Then to expand the target sites, we showed that two newly discovered CRISPR system, SaCas9 and AsCpf1, could also induce highly efficient site-specific genome editing in BmNs cells, and constructed an integrated CRISPR system. Genome-wide analysis of targetable sites was further conducted and showed that the integrated system cover 69,144,399 sites in B. mori genome, and one site could be found in every 6.5 bp. The efficiency and resolution of this CRISPR platform will probably accelerate both fundamental researches and applicable studies in B. mori, and perhaps other insects. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Alternate site surge capacity in times of public health disaster maintains trauma center and emergency department integrity: Hurricane Katrina.

    Science.gov (United States)

    Eastman, Alexander L; Rinnert, Kathy J; Nemeth, Ira R; Fowler, Raymond L; Minei, Joseph P

    2007-08-01

    Hospital surge capacity has been advocated to accommodate large increases in demand for healthcare; however, existing urban trauma centers and emergency departments (TC/EDs) face barriers to providing timely care even at baseline patient volumes. The purpose of this study is to describe how alternate-site medical surge capacity absorbed large patient volumes while minimizing impact on routine TC/ED operations immediately after Hurricane Katrina. From September 1 to 16, 2005, an alternate site for medical care was established. Using an off-site space, the Dallas Convention Center Medical Unit (DCCMU) was established to meet the increased demand for care. Data were collected and compared with TC/ED patient volumes to assess impact on existing facilities. During the study period, 23,231 persons displaced by Hurricane Katrina were registered to receive evacuee services in the City of Dallas, Texas. From those displaced, 10,367 visits for emergent or urgent healthcare were seen at the DCCMU. The mean number of daily visits (mean +/- SD) to the DCCMU was 619 +/- 301 visits with a peak on day 3 (n = 1,125). No patients died, 3.2% (n = 257) were observed in the DCCMU, and only 2.9% (n = 236) required transport to a TC/ED. During the same period, the mean number of TC/ED visits at the region's primary provider of indigent care (Hospital 1) was 346 +/- 36 visits. Using historical data from Hospital 1 during the same period of time (341 +/- 41), there was no significant difference in the mean number of TC/ED visits from the previous year (p = 0.26). Alternate-site medical surge capacity provides for safe and effective delivery of care to a large influx of patients seeking urgent and emergent care. This protects the integrity of existing public hospital TC/ED infrastructure and ongoing operations.

  14. High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion.

    Directory of Open Access Journals (Sweden)

    Claudia Cattoglio

    2010-12-01

    Full Text Available The infusion of donor lymphocytes transduced with a retroviral vector expressing the HSV-TK suicide gene in patients undergoing hematopoietic stem cell transplantation for leukemia/lymphoma promotes immune reconstitution and prevents infections and graft-versus-host disease. Analysis of the clonal dynamics of genetically modified lymphocytes in vivo is of crucial importance to understand the potential genotoxic risk of this therapeutic approach. We used linear amplification-mediated PCR and pyrosequencing to build a genome-wide, high-definition map of retroviral integration sites in the genome of peripheral blood T cells from two different donors and used gene expression profiling and bioinformatics to associate integration clusters to transcriptional activity and to genetic and epigenetic features of the T cell genome. Comparison with matched random controls and with integrations obtained from CD34(+ hematopoietic stem/progenitor cells showed that integration clusters occur within chromatin regions bearing epigenetic marks associated with active promoters and regulatory elements in a cell-specific fashion. Analysis of integration sites in T cells obtained ex vivo two months after infusion showed no evidence of integration-related clonal expansion or dominance, but rather loss of cells harboring integration events interfering with RNA post-transcriptional processing. The study shows that high-definition maps of retroviral integration sites are a powerful tool to analyze the fate of genetically modified T cells in patients and the biological consequences of retroviral transduction.

  15. ANALYSIS OF SUFFICIENCY OF THE BEARING CAPACITY OF BUILDING STRUCTURES OF OPERATING SITES OF MAIN BUILDINGS OF THERMAL POWER PLANTS

    Directory of Open Access Journals (Sweden)

    Alekseeva Ekaterina Leonidovna

    2012-10-01

    Full Text Available Upon examination of eleven main buildings of power plants, analysis of defects and damages of building structures was performed. Thereafter, the damageability of principal bearing structures of main buildings of thermal plants was analyzed. It was identified that the fastest growing defects and damages were concentrated in the structures of operating sites. The research of the rate of development of the most frequent damages and defects made it possible to conclude that internal corrosion of the reinforcing steel was the most dangerous defect, as far as the reinforced concrete elements of operating sites were concerned. Methods of mathematical statistics were applied to identify the reinforcing steel development pattern inside reinforced concrete elements of floors of operating sites. It was identified that the probability of corrosion of reinforced concrete elements of operating sites was distributed in accordance with the demonstrative law. Based on these data, calculation of strength of reinforced concrete slabs and metal beams was performed in terms of their regular sections, given the natural loads and the realistic condition of structures. As a result, dependence between the bearing capacity reserve ratio and the corrosion development pattern was identified for reinforced concrete slabs and metal beams of operating sites. In order to analyze the sufficiency of the bearing capacity of building structures of operating sites in relation to their time in commission, equations were derived to identify the nature of dependence between the sufficiency of the bearing capacity of reinforced concrete slabs and metal beams of the operating sites and their time in commission.

  16. Electric and Hybrid Vehicle Program: Site Operation Program. Quarterly progress report, July--September 1995

    Energy Technology Data Exchange (ETDEWEB)

    Francfort, J.; Bassett, R.R.; Briasco, S. [and others

    1995-12-01

    The Site Operator Program has evolved substantially since its inception in response to the Electric Vehicle Research and Demonstration Act of 1976. In its original form, a commercialization effort was intended but this was not feasible for lack of vehicle suppliers and infrastructure. Nonetheless, with DOE sponsorship and technical participation, a few results (primarily operating experience and data) were forthcoming. The current Program comprises eleven sites and over 200 vehicles, of which about 50 are latest generation vehicles. DOE partially funds the Program participant expenditures and the INEL receives operating and maintenance data for the DOE-owned, and participant-owned or monitored vehicles, as well as Program reports. As noted elsewhere in this report, participants represent several widely differing categories: electric utilities, academic institutions, and federal agencies. While both the utilities and the academic institutions tend to establish beneficial relationships with the industrial community.

  17. Closure report for CAU 339: Area 12 Fleet Operations steam-cleaning discharge area, Nevada Test Site

    International Nuclear Information System (INIS)

    1997-12-01

    This Closure Report (CR) provides documentation of the completed corrective action at the Area 12 Fleet Operations site located in the southeast portion of the Area 12 Camp at the Nevada Test Site (NTS). Field work was performed in July 1997 as outlined in the Corrective Action Plan (CAP). The CAP was approved by the Nevada Division of Environmental Protection (NDEP) in June 1997. This site is identified in the Federal Facility Agreement and Consent Order (FFACO) as Corrective Action Site (CAS) Number 12-19-01 and is the only CAS in Corrective Action Unit (CAU) 339. The former Area 12 Fleet Operations Building 12-16 functioned as a maintenance facility for light- and heavy-duty vehicles from approximately 1965 to January 1993. Services performed at the site included steam-cleaning, tire service, and preventative maintenance on vehicles and equipment. Past activities impacted the former steam-cleaning discharge area with volatile organic compounds (VOCs) and total petroleum hydrocarbons (TPH) as oil

  18. Testing an integrated model of operations capabilities An empirical study of Australian airlines

    NARCIS (Netherlands)

    Nand, Alka Ashwini; Singh, Prakash J.; Power, Damien

    2013-01-01

    Purpose - The purpose of this paper is to test the integrated model of operations strategy as proposed by Schmenner and Swink to explain whether firms trade-off or accumulate capabilities, taking into account their positions relative to their asset and operating frontiers.

  19. Advance pre-operative chlorhexidine reduces the incidence of surgical site infections in knee arthroplasty.

    Science.gov (United States)

    Zywiel, Michael G; Daley, Jacqueline A; Delanois, Ronald E; Naziri, Qais; Johnson, Aaron J; Mont, Michael A

    2011-07-01

    Surgical site infections following elective knee arthroplasties occur most commonly as a result of colonisation by the patient's native skin flora. The purpose of this study was to evaluate the incidence of deep surgical site infections in knee arthroplasty patients who used an advance cutaneous disinfection protocol and who were compared to patients who had peri-operative preparation only. All adult reconstruction surgeons at a single institution were approached to voluntarily provide patients with chlorhexidine gluconate-impregnated cloths and a printed sheet instructing their use the night before and morning of surgery. Records for all knee arthroplasties performed between January 2007 and December 2008 were reviewed to determine the incidence of deep incisional and periprosthetic surgical site infections. Overall, the advance pre-operative protocol was used in 136 of 912 total knee arthroplasties (15%). A lower incidence of surgical site infection was found in patients who used the advance cutaneous preparation protocol as compared to patients who used the in-hospital protocol alone. These findings were maintained when patients were stratified by surgical infection risk category. No surgical site infections occurred in the 136 patients who completed the protocol as compared to 21 infections in 711 procedures (3.0%) performed in patients who did not. Patient-directed skin disinfection using chlorhexidine gluconate-impregnated cloths the evening before, and the morning of, elective knee arthroplasty appeared to effectively reduce the incidence of surgical site infection when compared to patients who underwent in-hospital skin preparation only.

  20. Mound site environmental report for calendar year 1992

    International Nuclear Information System (INIS)

    Bauer, L.R.

    1993-07-01

    The purpose of this report is to inform the public about the impact of Mound operations on the population and the environment. Mound is a government-owned facility operated by EG ampersand G Mound Applied Technologies for the US Department of Energy (DOE). This integrated production, development, and research site performs work in support of DOE's weapon and energy related programs, with emphasis on explosive, nuclear and energy technologies

  1. RCRA facility investigation/corrective measures study work plan for the 100-HR-1 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US. Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under the Hanford Federal Facility Agreement and Consent Order, signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1,000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste, and other CERCLA hazardous substances. This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the RCRA facility investigation/corrective measures study (RFI/CMS) for the 100-HR-1 source operable unit. Source operable units include facilities and unplanned release sites that are potential sources of contamination. The 100-HR-3 operable unit underlies the D/DR and H Areas, the 600 Area between them, and the six source operable units these areas contain. The 100-HR-3 operable unit includes all contamination found in the aquifer soils and water within its boundary. Separate work plans have been initiated for the 100-HR-3 groundwater operable unit (DOE-RL 1992a) and the 100-DR-1 (DOE-RL 1992b) source operable units

  2. Alaska Center for Unmanned Aircraft Systems Integration (ACUASI): Operational Support and Geoscience Research

    Science.gov (United States)

    Webley, P. W.; Cahill, C. F.; Rogers, M.; Hatfield, M. C.

    2016-12-01

    Unmanned Aircraft Systems (UAS) have enormous potential for use in geoscience research and supporting operational needs from natural hazard assessment to the mitigation of critical infrastructure failure. They provide a new tool for universities, local, state, federal, and military organizations to collect new measurements not readily available from other sensors. We will present on the UAS capabilities and research of the Alaska Center for Unmanned Aircraft Systems Integration (ACUASI, http://acuasi.alaska.edu/). Our UAS range from the Responder with its dual visible/infrared payload that can provide simultaneous data to our new SeaHunter UAS with 90 lb. payload and multiple hour flight time. ACUASI, as a designated US Federal Aviation Administration (FAA) test center, works closely with the FAA on integrating UAS into the national airspace. ACUASI covers all aspects of working with UAS from pilot training, airspace navigation, flight operations, and remote sensing analysis to payload design and integration engineers and policy experts. ACUASI's recent missions range from supporting the mapping of sea ice cover for safe passage of Alaskans across the hazardous winter ice to demonstrating how UAS can be used to provide support during oil spill response. Additionally, we will present on how ACUASI has worked with local authorities in Alaska to integrate UAS into search and rescue operations and with NASA and the FAA on their UAS Transport Management (UTM) project to fly UAS within the manned airspace. ACUASI is also working on developing new capabilities to sample volcanic plumes and clouds, map forest fire impacts and burn areas, and develop a new citizen network for monitoring snow extent and depth during Northern Hemisphere winters. We will demonstrate how UAS can be integrated in operational support systems and at the same time be used in geoscience research projects to provide high precision, accurate, and reliable observations.

  3. Mucinous adenocarcinoma arising at the anastomotic site after operation for hirschsprung's disease: case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyung Soo; Yoon, Kwon Ha [College of Medicine, Wonkwang Univ., Iksan (Korea, Republic of)

    2004-02-01

    To our knowledge, rectal cancer arising at the anastomotic site after surgery for Hirschsprung's disease has not been reported. We report a case of mucinous adenocarcinoma arising at the anastomotic site after Soave operation 26 years ago.

  4. Integrated electrofluidic circuits: pressure sensing with analog and digital operation functionalities for microfluidics.

    Science.gov (United States)

    Wu, Chueh-Yu; Lu, Jau-Ching; Liu, Man-Chi; Tung, Yi-Chung

    2012-10-21

    Microfluidic technology plays an essential role in various lab on a chip devices due to its desired advantages. An automated microfluidic system integrated with actuators and sensors can further achieve better controllability. A number of microfluidic actuation schemes have been well developed. In contrast, most of the existing sensing methods still heavily rely on optical observations and external transducers, which have drawbacks including: costly instrumentation, professional operation, tedious interfacing, and difficulties of scaling up and further signal processing. This paper reports the concept of electrofluidic circuits - electrical circuits which are constructed using ionic liquid (IL)-filled fluidic channels. The developed electrofluidic circuits can be fabricated using a well-developed multi-layer soft lithography (MSL) process with polydimethylsiloxane (PDMS) microfluidic channels. Electrofluidic circuits allow seamless integration of pressure sensors with analog and digital operation functions into microfluidic systems and provide electrical readouts for further signal processing. In the experiments, the analog operation device is constructed based on electrofluidic Wheatstone bridge circuits with electrical outputs of the addition and subtraction results of the applied pressures. The digital operation (AND, OR, and XOR) devices are constructed using the electrofluidic pressure controlled switches, and output electrical signals of digital operations of the applied pressures. The experimental results demonstrate the designed functions for analog and digital operations of applied pressures are successfully achieved using the developed electrofluidic circuits, making them promising to develop integrated microfluidic systems with capabilities of precise pressure monitoring and further feedback control for advanced lab on a chip applications.

  5. OR.NET: multi-perspective qualitative evaluation of an integrated operating room based on IEEE 11073 SDC.

    Science.gov (United States)

    Rockstroh, M; Franke, S; Hofer, M; Will, A; Kasparick, M; Andersen, B; Neumuth, T

    2017-08-01

    Clinical working environments have become very complex imposing many different tasks in diagnosis, medical treatment, and care procedures. During the German flagship project OR.NET, more than 50 partners developed technologies for an open integration of medical devices and IT systems in the operating room. The aim of the present work was to evaluate a large set of the proposed concepts from the perspectives of various stakeholders. The demonstration OR is focused on interventions from the head and neck surgery and was developed in close cooperation with surgeons and numerous colleagues of the project partners. The demonstration OR was qualitatively evaluated including technical as well as clinical aspects. In the evaluation, a questionnaire was used to obtain feedback from hospital operators. The clinical implications were covered by structured interviews with surgeons, anesthesiologists and OR staff. In the present work, we qualitatively evaluate a subset of the proposed concepts from the perspectives of various stakeholders. The feedback of the clinicians indicates that there is a need for a flexible data and control integration. The hospital operators stress the need for tools to simplify risk management in openly integrated operating rooms. The implementation of openly integrated operating rooms will positively affect the surgeons, the anesthesiologists, the surgical nursing staff, as well as the technical personnel and the hospital operators. The evaluation demonstrated the need for OR integration technologies and identified the missing tools to support risk management and approval as the main barriers for future installments.

  6. Weather integration in TMC operations : a self-evaluation and planning guide.

    Science.gov (United States)

    2009-04-01

    This flyer describes how Traffic Management Centers (TMC) can integrate weather information into their daily operations, and is based on the Road Weather Management Program publication, Self-Evaluation and Planning Guide (FHWA-JPO-08-057). The Guide ...

  7. Site-specific integration of CAR gene into Jurkat T cells with a linear close-ended AAV-based DNA vector for CAR-T engineering.

    Science.gov (United States)

    Zhang, Yun; Liu, Xiaomei; Zhang, Jinju; Zhang, Chun

    2016-09-01

    To develop a site-specific integration strategy for CAR-T engineering by using a non-viral vector dependent on adeno-associated viral (AAV) genome, which tends to be integrated into AAVS1 site with the help of its Rep proteins. AAV-dependent vectors were produced in Sf9 cells. Structural analyses revealed the vector as covalently close-ended, linear duplex molecules, which was termed "CELiD" DNA. A plasmid CMV-Rep was constructed to express the integrases Rep78 and Rep68. Jurkat cells were co-electroporated with "CELiD" DNA and plasmid CMV-Rep in order to specifically integrate CAR gene into AAVS1 site. We examined 71 stably transfected Jurkat clones by nested PCR, sequencing and southern blotting, of which 30 clones bore CAR gene within AAVS1 site. The site-specific integration efficiency was nearly 42.2 %. The AAV-dependent vector preferentially integrated CAR into AAVS1 site, which could be further used in human T cell modification and enhance the security of CAR-T therapy.

  8. Integration of a browser based operator manual in the system environment of a process computer system

    International Nuclear Information System (INIS)

    Weber, Andreas; Erfle, Robert; Feinkohl, Dirk

    2012-01-01

    The integration of a browser based operator manual in the system environment of a process computer system is an optimization of the operating procedure in the control room and a safety enhancement due to faster and error-free access to the manual contents. Several requirements by the authorities have to be fulfilled: the operating manual has to be available as hard copy, the format has to be true to original, protection against manipulation has to be provided, the manual content of the browser-based version and the hard copy have to identical, and the display presentation has to be consistent with ergonomic principals. The integration of the on-line manual in the surveillance process computer system provides the operator with the relevant comments to the surveillance signal. The described integration of the on-line manual is an optimization of the operator's everyday job with respect to ergonomics and safety (human performance).

  9. Site Environmental Report for Calendar Year 2000. DOE Operations at The Boeing Company, Rocketdyne Propulsion & Power

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Phil [The Boeing Company, Canoga Park, CA (United States); Samuels, Sandy [The Boeing Company, Canoga Park, CA (United States); Lee, Majelle [The Boeing Company, Canoga Park, CA (United States)

    2001-09-01

    This Annual Site Environmental Report (ASER) for 2000 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of the Rocketdyne Santa Susana Field Laboratory (SSFL). In the past, these operations included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials, under the former Atomics International (AI) Division. Other activities included the operation of large-scale liquid metal facilities for testing of liquid metal fast breeder components at the Energy Technology Engineering Center (ETEC), a government-owned company-operated, test facility within Area IV. All nuclear work was terminated in 1988, and subsequently, all radiological work has been directed toward decontamination and decommissioning (D&D) of the previously used nuclear facilities and associated site areas. Large-scale D&D activities of the sodium test facilities began in 1996. Results of the radiological monitoring program for the calendar year of 2000 continue to indicate no significant releases of radioactive material from Rocketdyne sites. All potential exposure pathways are sampled and/or monitored, including air, soil, surface water, groundwater, direct radiation, transfer of property (land, structures, waste), and recycling. All radioactive wastes are processed for disposal at DOE disposal sites and other sites approved by DOE and licensed for radioactive waste. Liquid radioactive wastes are not released into the environment and do not constitute an exposure pathway.

  10. Electric and Hybrid Vehicle Program, Site Operator Program. Quarterly progress report, October--December 1995 (first quarter of fiscal year 1996)

    Energy Technology Data Exchange (ETDEWEB)

    Francfort, J.E. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States); Bassett, R.R. [Sandia National Labs., Albuquerque, NM (United States); Briasco, S. [Los Angeles Dept. of Water and Power, CA (United States)] [and others

    1996-03-01

    This is the Site Operator Program quarterly report for USDOE electric and hybrid vehicle research. Its mission now includes the three major activity categories of advancement of electric vehicle (EV) technologies, development of infrastructure elements needed to support significant EV use and increasing public awareness and acceptance of EVs. The 11 Site Operator Program participants, their geographic locations, and the principal thrusts of their efforts are identified. The EV inventories of the site operators totals about 250 vehicles. The individual fleets are summarized.

  11. Department of Energy Site Operator Program. Final report, October 1, 1991--September 31, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    York Technical College is a two-year public institution accredited by the Commission of Colleges of the Southern Association of Colleges and Schools. York Technical College has been involved with electric vehicles since the late 1980`s. The four major objectives of the Site Operator Program were (1) field test and evaluate electric and hybrid vehicles and related components; (2) define and develop a national infrastructure system including electric charging systems, service/training education programs, utility system impacts and safety standards; (3) increase public awareness regarding environmental benefits, reduced dependency on foreign oil, technology development, and economic impacts; (4) assist local, state and federal agencies and fleet operators in developing electric and hybrid vehicle programs. The primary thrusts of the electric vehicle program at York Technical College, supporting the objectives of the Site Operator program were: (1) public awareness, (2) public education, (3) EV maintenance curriculum development and maintenance training, (4) field data collection, (5) vehicle modification and upgrade, (6) establish electric vehicle partnerships.

  12. Infirmity and injury complexity are risk factors for surgical-site infection after operative fracture care.

    Science.gov (United States)

    Bachoura, Abdo; Guitton, Thierry G; Smith, R Malcolm; Vrahas, Mark S; Zurakowski, David; Ring, David

    2011-09-01

    Orthopaedic surgical-site infections prolong hospital stays, double rehospitalization rates, and increase healthcare costs. Additionally, patients with orthopaedic surgical-site infections (SSI) have substantially greater physical limitations and reductions in their health-related quality of life. However, the risk factors for SSI after operative fracture care are unclear. We determined the incidence and quantified modifiable and nonmodifiable risk factors for SSIs in patients with orthopaedic trauma undergoing surgery. We retrospectively indentified, from our prospective trauma database and billing records, 1611 patients who underwent 1783 trauma-related procedures between 2006 and 2008. Medical records were reviewed and demographics, surgery-specific data, and whether the patients had an SSI were recorded. We determined which if any variables predicted SSI. Six factors independently predicted SSI: (1) the use of a drain, OR 2.3, 95% CI (1.3-3.8); (2) number of operations OR 3.4, 95% CI (2.0-6.0); (3) diabetes, OR 2.1, 95% CI (1.2-3.8); (4) congestive heart failure (CHF), OR 2.8, 95% CI (1.3-6.5); (5) site of injury tibial shaft/plateau, OR 2.3, 95% CI (1.3-4.2); and (6) site of injury, elbow, OR 2.2, 95% CI (1.1-4.7). The risk factors for SSIs after skeletal trauma are most strongly determined by nonmodifiable factors: patient infirmity (diabetes and heart failure) and injury complexity (site of injury, number of operations, use of a drain). Level II, prognostic study. See the Guideline for Authors for a complete description of levels of evidence.

  13. I-880 Integrated Corridor Management Concept of Operation : Final Submittal: Concept of Operations for the I-880 Corridor in Oakland, California

    Science.gov (United States)

    2008-03-31

    This report describes the draft Concept of Operations that has been developed for the Integrated Corridor Mobility (ICM) program by the I-880 corridor team. The I-880 corridor team has defined this Concept of Operations (ConOps) based on two primary ...

  14. Integration of hydrothermal carbonization and a CHP plant: Part 2 –operational and economic analysis

    International Nuclear Information System (INIS)

    Saari, Jussi; Sermyagina, Ekaterina; Kaikko, Juha; Vakkilainen, Esa; Sergeev, Vitaly

    2016-01-01

    Wood-fired combined heat and power (CHP) plants are a proven technology for producing domestic, carbon-neutral heat and power in Nordic countries. One drawback of CHP plants is the low capacity factors due to varying heat loads. In the current economic environment, uncertainty over energy prices creates also uncertainty over investment profitability. Hydrothermal carbonization (HTC) is a promising thermochemical conversion technology for producing an improved, more versatile wood-based fuel. Integrating HTC with a CHP plant allows simplifying the HTC process and extending the CHP plant operating time. An integrated polygeneration plant producing three energy products is also less sensitive to price changes in any one product. This study compares three integration cases chosen from the previous paper, and the case of separate stand-alone plants. The best economic performance is obtained using pressurized hot water from the CHP plant boiler drum as HTC process water. This has the poorest efficiency, but allows the greatest cost reduction in the HTC process and longest CHP plant operating time. The result demonstrates the suitability of CHP plants for integration with a HTC process, and the importance of economic and operational analysis considering annual load variations in sufficient detail. - Highlights: • Integration of wood hydrothermal carbonization with a small CHP plant studied. • Operation and economics of three concepts and stand-alone plants are compared. • Sensitivity analysis is performed. • Results show technical and thermodynamic analysis inadequate and misleading alone. • Minimizing HTC investment, extending CHP operating time important for profitability.

  15. The role of pre-operative and post-operative glucose control in surgical-site infections and mortality.

    Directory of Open Access Journals (Sweden)

    Christie Y Jeon

    Full Text Available The impact of glucose control on surgical-site infection (SSI and death remains unclear. We examined how pre- and post-operative glucose levels and their variability are associated with the risk of SSI or in-hospital death.This retrospective cohort study employed data on 13,800 hospitalized patients who underwent a surgical procedure at a large referral hospital in New York between 2006 and 2008. Over 20 different sources of electronic data were used to analyze how thirty-day risk of SSI and in-hospital death varies by glucose levels and variability. Maximum pre- and post-operative glucose levels were determined for 72 hours before and after the operation and glucose variability was defined as the coefficient of variation of the glucose measurements. We employed logistic regression to model the risk of SSI or death against glucose variables and the following potential confounders: age, sex, body mass index, duration of operation, diabetes status, procedure classification, physical status, emergency status, and blood transfusion.While association of pre- and post-operative hyperglycemia with SSI were apparent in the crude analysis, multivariate results showed that SSI risk did not vary significantly with glucose levels. On the other hand, in-hospital deaths were associated with pre-operative hypoglycemia (OR = 5.09, 95% CI (1.80, 14.4 and glucose variability (OR = 1.14, 95% CI (1.03, 1.27 for 10% increase in coefficient of variation.In-hospital deaths occurred more often among those with pre-operative hypoglycemia and higher glucose variability. These findings warrant further investigation to determine whether stabilization of glucose and prevention of hypoglycemia could reduce post-operative deaths.

  16. The role of pre-operative and post-operative glucose control in surgical-site infections and mortality.

    Science.gov (United States)

    Jeon, Christie Y; Furuya, E Yoko; Berman, Mitchell F; Larson, Elaine L

    2012-01-01

    The impact of glucose control on surgical-site infection (SSI) and death remains unclear. We examined how pre- and post-operative glucose levels and their variability are associated with the risk of SSI or in-hospital death. This retrospective cohort study employed data on 13,800 hospitalized patients who underwent a surgical procedure at a large referral hospital in New York between 2006 and 2008. Over 20 different sources of electronic data were used to analyze how thirty-day risk of SSI and in-hospital death varies by glucose levels and variability. Maximum pre- and post-operative glucose levels were determined for 72 hours before and after the operation and glucose variability was defined as the coefficient of variation of the glucose measurements. We employed logistic regression to model the risk of SSI or death against glucose variables and the following potential confounders: age, sex, body mass index, duration of operation, diabetes status, procedure classification, physical status, emergency status, and blood transfusion. While association of pre- and post-operative hyperglycemia with SSI were apparent in the crude analysis, multivariate results showed that SSI risk did not vary significantly with glucose levels. On the other hand, in-hospital deaths were associated with pre-operative hypoglycemia (OR = 5.09, 95% CI (1.80, 14.4)) and glucose variability (OR = 1.14, 95% CI (1.03, 1.27) for 10% increase in coefficient of variation). In-hospital deaths occurred more often among those with pre-operative hypoglycemia and higher glucose variability. These findings warrant further investigation to determine whether stabilization of glucose and prevention of hypoglycemia could reduce post-operative deaths.

  17. A journey to zero: reduction of post-operative cesarean surgical site infections over a five-year period.

    Science.gov (United States)

    Hickson, Evelyn; Harris, Jeanette; Brett, David

    2015-04-01

    Surgical site infections (SSI) are a substantial concern for cesarean deliveries in which a surgical site complication is most unwelcome for a mother with a new infant. Steps taken pre- and post-operatively to reduce the number of complications may be of substantial benefit clinically, economically, and psychologically. A risk-based approach to incision management was developed and implemented for all cesarean deliveries at our institution. A number of incremental interventions for low-risk and high-risk patients including pre-operative skin preparations, standardized pre- and post-operative protocols, post-operative nanocrystalline silver anti-microbial barrier dressings, and incisional negative pressure wound therapy (NPWT) were implemented sequentially over a 5-y period. A systematic clinical chart review of 4,942 patients spanning all cesarean deliveries between 2007-2012 was performed to determine what effects the interventions had on the rate of SSI for cesarean deliveries. The percentage of SSI was reduced from 2.13% (2007) to 0.10% (2012) (poperative SSIs were avoided: A total cost saving of nearly $5,000,000. Applying a clinical algorithm for assessing the risk of surgical site complication and making recommendations on pre-operative and post-operative incision management can result in a substantial and sustainable reduction in cesarean SSI.

  18. An Integrated Approach to the Teaching of Operations Management in a Business School

    Science.gov (United States)

    Misra, Ram B.; Ravinder, Handanhal; Peterson, Richard L.

    2016-01-01

    The authors discuss a curriculum integration effort that a school of business piloted recently. This effort was aimed at integrating the core functions (finance, marketing, management, and operations) so that undergraduate students would better appreciate the full impact of functional decisions on each other and in achieving the corporation's…

  19. The Role of MOR and the CI Operator Sites on the Genetic Switch of the Temperate Bacteriophage TP901-1

    DEFF Research Database (Denmark)

    Pedersen, Margit; Hammer, Karin

    2008-01-01

    . The cloned DNA fragment contained the two divergently oriented promoters, P-R and P-L, transcribing the lysogenic and lytic gene clusters; the two promoter-. proximal genes, cl and mor; and the three CI operator sites, O-R, O-L and O-D. We show that mor encodes a protein and that this protein in concert......-D) is enough to maintain a bistable system. The distantly located operator site, 01:), functions as a helper site by increasing binding of CI at O-R and O-L. In the immune state, O-D increases repression of the lytic promoter, P-L. Our results strongly support the model that a hexameric form of Cl binds...... cooperatively to the three operator sites in the immune state forming a CI-DNA loop structure. Finally, we show that in the anti-immune state, repression of the lysogenic promoter is independent of the known CI operator sites but requires the presence of both CI and MOR....

  20. New operator-ordering identities and associative integration formulas of two-variable Hermite polynomials for constructing non-Gaussian states

    International Nuclear Information System (INIS)

    Fan Hong-Yi; Wang Zhen

    2014-01-01

    For directly normalizing the photon non-Gaussian states (e.g., photon added and subtracted squeezed states), we use the method of integration within an ordered product (IWOP) of operators to derive some new bosonic operator-ordering identities. We also derive some new integration transformation formulas about one- and two-variable Hermite polynomials in complex function space. These operator identities and associative integration formulas provide much convenience for constructing non-Gaussian states in quantum engineering. (general)

  1. The relation between operator and path integral covariant quantizations of the Green-Schwarz superstring

    International Nuclear Information System (INIS)

    Nissimov, E.; Pacheva, S.; Solomon, S.

    1989-02-01

    By further study of the geometry of the harmonic superspace constraints, we make explicit the relation between the operator and path integral approaches to the manifestly covariant harmonic superstring. In particular we find the correct complete set of functionally independent gauge symmetries for the auxiliary variables and identify the ones corresponding to the harmonic superfield postulate in the operator formalism. Then, we deduce in a systematic way the lagrangian path integral from the well defined covariant hamiltonian formulation of the GS superstring. (authors)

  2. Improving Integrated Operation in the Joint Integrated Mission Model (JIMM) and the Simulated Warfare Environment Data Transfer (SWEDAT) Protocol

    National Research Council Canada - National Science Library

    Mutschler, David W

    2005-01-01

    ...). It allows integrated operation of resources whereby the JIMM threat environment, stimulators virtual cockpits, systems under test, and other agents are combined within the same simulation exercise...

  3. Safety and emergency preparedness considerations for geotechnical field operations

    Energy Technology Data Exchange (ETDEWEB)

    Wemple, R.P.

    1989-04-01

    The GEO Energy Technology Department at Sandia National Laboratories is involved in several remote-site drilling and/or experimental operations each year. In 1987, the Geothermal Research Division of the Department developed a general set of Safe Operating Procedures (SOPs) that could be applied to a variety of projects. This general set is supplemented by site-specific SOPs as needed. Effective field operations require: integration of safety and emergency preparedness planning with overall project planning, training of field personnel and inventorying of local emergency support resources, and, developing a clear line of responsibility and authority to enforce the safety requirements. Copies of SOPs used in recent operations are included as examples of working documents for the reader.

  4. Hanford Site Solid Waste Landfill permit application

    International Nuclear Information System (INIS)

    1991-01-01

    Daily activities at the Hanford Site generate sanitary solid waste (nonhazardous and nonradioactive) that is transported to and permanently disposed of at the Hanford Site Solid Waste Landfill. This permit application describes the manner in which the solid Waste Landfill will be operated under Washington State Department of Ecology Minimum Functional Standards for Solid Waste Handling, Washington Administrative Code 173-304. The solid Waste Landfill is owned by the US Department of Energy -- Richland Operations Office and is used for disposal of solid waste generated at the US Department of Energy Hanford Site. The jurisdictional health department's permit application form for the Solid Waste Landfill is provided in Chapter 1.0. Chapter 2.0 provides a description of the Hanford Site and the Solid Waste Landfill and reviews applicable locational, general facility, and landfilling standards. Chapter 3.0 discusses the characteristics and quantity of the waste disposed of in the Solid Waste Landfill. Chapter 4.0 reviews the regional and site geology and hydrology and the groundwater and vadose zone quality beneath the landfill. Chapters 5.0, 6.0, and 7.0 contain the plan of operation, closure plan, and postclosure plan, respectively. The plan of operation describes the routine operation and maintenance of the Solid Waste Landfill, the environmental monitoring program, and the safety and emergency plans. Chapter 5.0 also addresses the operational cover, environmental controls, personnel requirements, inspections, recordkeeping, reporting, and site security. The postclosure plan describes requirements for final cover maintenance and environmental monitoring equipment following final closure. Chapter 8.0 discusses the integration of closure and postclosure activities between the Solid Waste Landfill and adjacent Nonradioactive Dangerous Waste Landfill. 76 refs., 48 figs, 15 tabs

  5. Integrated Assessment Plan Template and Operational Demonstration for SPIDERS Phase 2: Fort Carson

    Energy Technology Data Exchange (ETDEWEB)

    Barr, Jonathan L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tuffner, Francis K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hadley, Mark D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kreyling, Sean J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Schneider, Kevin P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-09-01

    This document contains the Integrated Assessment Plan (IAP) for the Phase 2 Operational Demonstration (OD) of the Smart Power Infrastructure Demonstration for Energy Reliability (SPIDERS) Joint Capability Technology Demonstration (JCTD) project. SPIDERS will be conducted over a three year period with Phase 2 being conducted at Fort Carson, Colorado. This document includes the Operational Demonstration Execution Plan (ODEP) and the Operational Assessment Execution Plan (OAEP), as approved by the Operational Manager (OM) and the Integrated Management Team (IMT). The ODEP describes the process by which the OD is conducted and the OAEP describes the process by which the data collected from the OD is processed. The execution of the OD, in accordance with the ODEP and the subsequent execution of the OAEP, will generate the necessary data for the Quick Look Report (QLR) and the Utility Assessment Report (UAR). These reports will assess the ability of the SPIDERS JCTD to meet the four critical requirements listed in the Implementation Directive (ID).

  6. Hanford Integrated Planning Process: 1993 Hanford Site-specific science and technology plan

    International Nuclear Information System (INIS)

    1993-12-01

    This document is the FY 1993 report on Hanford Site-specific science and technology (S ampersand T) needs for cleanup of the Site as developed via the Hanford Integrated Planning Process (HIPP). It identifies cleanup problems that lack demonstrated technology solutions and technologies that require additional development. Recommendations are provided regarding allocation of funding to address Hanford's highest-priority technology improvement needs, technology development needs, and scientific research needs, all compiled from a Sitewide perspective. In the past, the S ampersand T agenda for Hanford Site cleanup was sometimes driven by scientists and technologists, with minimal input from the ''problem owners'' (i.e., Westinghouse Hanford Company [WHC] staff who are responsible for cleanup activities). At other times, the problem-owners made decisions to proceed with cleanup without adequate scientific and technological inputs. Under both of these scenarios, there was no significant stakeholder involvement in the decision-making process. One of the key objectives of HIPP is to develop an understanding of the integrated S ampersand T requirements to support the cleanup mission, (a) as defined by the needs of the problem owners, the values of the stakeholders, and the technology development expertise that exists at Hanford and elsewhere. This requires a periodic, systematic assessment of these needs and values to appropriately define a comprehensive technology development program and a complementary scientific research program. Basic to our success is a methodology that is defensible from a technical perspective and acceptable to the stakeholders

  7. Radiological dose assessment from the operation of Daeduk nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Won Tae; Kim, Eun Han; Suh, Kyung Suk; Choi, Young Gil [Korea Atomic Energy Research Institute, Taejon (Korea)

    2000-02-01

    The objective of this project is to assure the public acceptance for nuclear facilities, and the environmental safety from the operation of Daeduk nuclear facilities, such as HANARO research reactor, nuclear fuel processing facilities and others. For identifying the integrity of their facilities, the maximum individual doses at the site boundary and on the areas with high population density were assessed. Also, the collective doses within radius 80 km from the site were assessed. The radiation impacts for residents around the site from the operation of Daeduk nuclear facilities in 1999 were neglectable. 8 refs., 10 figs., 27 tabs. (Author)

  8. Integrated model of port oil piping transportation system safety including operating environment threats

    Directory of Open Access Journals (Sweden)

    Kołowrocki Krzysztof

    2017-06-01

    Full Text Available The paper presents an integrated general model of complex technical system, linking its multistate safety model and the model of its operation process including operating environment threats and considering variable at different operation states its safety structures and its components safety parameters. Under the assumption that the system has exponential safety function, the safety characteristics of the port oil piping transportation system are determined.

  9. Integrated model of port oil piping transportation system safety including operating environment threats

    OpenAIRE

    Kołowrocki, Krzysztof; Kuligowska, Ewa; Soszyńska-Budny, Joanna

    2017-01-01

    The paper presents an integrated general model of complex technical system, linking its multistate safety model and the model of its operation process including operating environment threats and considering variable at different operation states its safety structures and its components safety parameters. Under the assumption that the system has exponential safety function, the safety characteristics of the port oil piping transportation system are determined.

  10. Software features and applications in process design, integration and operation

    Energy Technology Data Exchange (ETDEWEB)

    Dhole, V. [Aspen Tech Limited, Warrington (United Kingdom)

    1999-02-01

    Process engineering technologies and tools have evolved rapidly over the last twenty years. Process simulation/modeling, advanced process control, on-line optimisation, production planning and supply chain management are some of the examples of technologies that have rapidly matured from early commercial prototypes and concepts to established tools with significant impact on profitability of process industry today. Process Synthesis or Process Integration (PI) in comparison is yet to create its impact and still remains largely in the domain of few expert users. One of the key reasons as to why PI has not taken off is because the PI tools have not become integral components of the standard process engineering environments. On the last 15 years AspenTech has grown from a small process simulation tool provider to a large multinational company providing a complete suite of process engineering technologies and services covering process design, operation, planning and supply chain management. Throughout this period, AspenTech has acquired experience in rapidly evolving technologies from their early prototype stage to mature products and services. The paper outlines AspenTech`s strategy of integrating PI with other more established process design and operational improvement technologies. The paper illustrates the key elements of AspenTech`s strategy via examples of software development initiatives and services projects. The paper also outlines AspenTech`s future vision of the role of PI in process engineering. (au)

  11. Botanical aspects of the ecological integrity of a radioactive waste disposal site

    International Nuclear Information System (INIS)

    Hall, A.V.

    1986-01-01

    Botanical factors play a key role in maintaining the long term integrity of ecosystems. The results of botanical research at the Vaalputs radioactive waste disposal site in Bushmanland, South Africa, are outlined. Vaalputs is in an arid region and its vegetation is a patchy mosaic of low shrub and grass communities. Soil variation from site to site is the main determinant of community structure and erratic precipitation is a major stochastic forcing factor. Management measures to conserve taxa, ecosystems and local genetic biogeography are discussed in relation to natural and artificial disturbances which may occur over long time-scales. Restoration of vegetation over the burial trenches should as far as possible be to the site's former ecotypes except that deep-rooted species should be excluded. Precautions should be taken against the accidental establishment of exotic plant invaders at Vaalputs especially if they are deep-rooted. More is now known about plant ecology at Vaalputs than any other part of Bushmanland. It would be valuable to develop such studies further and establish Vaalputs as a permanent reserve for arid-zone biological research

  12. The Role of Pre-Operative and Post-Operative Glucose Control in Surgical-Site Infections and Mortality

    OpenAIRE

    Jeon, Christie Y.; Furuya, E. Yoko; Berman, Mitchell F.; Larson, Elaine L.

    2012-01-01

    Background and Objective The impact of glucose control on surgical-site infection (SSI) and death remains unclear. We examined how pre- and post-operative glucose levels and their variability are associated with the risk of SSI or in-hospital death. Methods This retrospective cohort study employed data on 13,800 hospitalized patients who underwent a surgical procedure at a large referral hospital in New York between 2006 and 2008. Over 20 different sources of electronic data were used to anal...

  13. Spectra of random operators with absolutely continuous integrated density of states

    International Nuclear Information System (INIS)

    Rio, Rafael del

    2014-01-01

    The structure of the spectrum of random operators is studied. It is shown that if the density of states measure of some subsets of the spectrum is zero, then these subsets are empty. In particular follows that absolute continuity of the integrated density of states implies singular spectra of ergodic operators is either empty or of positive measure. Our results apply to Anderson and alloy type models, perturbed Landau Hamiltonians, almost periodic potentials, and models which are not ergodic

  14. Spectra of random operators with absolutely continuous integrated density of states

    Energy Technology Data Exchange (ETDEWEB)

    Rio, Rafael del, E-mail: delrio@iimas.unam.mx, E-mail: delriomagia@gmail.com [Departamento de Fisica Matematica, Instituto de Investigaciones en Matemáticas Aplicadas y en Sistemas, Universidad Nacional Autónoma de México, C.P. 04510, México D.F. (Mexico)

    2014-04-15

    The structure of the spectrum of random operators is studied. It is shown that if the density of states measure of some subsets of the spectrum is zero, then these subsets are empty. In particular follows that absolute continuity of the integrated density of states implies singular spectra of ergodic operators is either empty or of positive measure. Our results apply to Anderson and alloy type models, perturbed Landau Hamiltonians, almost periodic potentials, and models which are not ergodic.

  15. Secure, Autonomous, Intelligent Controller for Integrating Distributed Emergency Response Satellite Operations

    Science.gov (United States)

    Ivancic, William D.; Paulsen, Phillip E.; Miller, Eric M.; Sage, Steen P.

    2013-01-01

    This report describes a Secure, Autonomous, and Intelligent Controller for Integrating Distributed Emergency Response Satellite Operations. It includes a description of current improvements to existing Virtual Mission Operations Center technology being used by US Department of Defense and originally developed under NASA funding. The report also highlights a technology demonstration performed in partnership with the United States Geological Service for Earth Resources Observation and Science using DigitalGlobe(Registered TradeMark) satellites to obtain space-based sensor data.

  16. Dam safety operating guidelines

    International Nuclear Information System (INIS)

    Elsayed, E.; Leung, T.; Kirkham, A.; Lum, D.

    1990-01-01

    As part of Ontario Hydro's dam structure assessment program, the hydraulic design review of several river systems has revealed that many existing dam sites, under current operating procedures, would not have sufficient discharge capacity to pass the Inflow Design Flood (IDF) without compromising the integrity of the associated structures. Typical mitigative measures usually considered in dealing with these dam sites include structural alterations, emergency action plans and/or special operating procedures designed for extreme floods. A pilot study was carried out for the Madawaska River system in eastern Ontario, which has seven Ontario Hydro dam sites in series, to develop and evaluate the effectiveness of the Dam Safety Operating Guidelines (DSOG). The DSOG consist of two components: the flood routing schedules and the minimum discharge schedules, the former of which would apply in the case of severe spring flood conditions when the maximum observed snowpack water content and the forecast rainfall depth exceed threshold values. The flood routing schedules would identify to the operator the optimal timing and/or extent of utilizing the discharge facilities at each dam site to minimize the potential for dam failures cased by overtopping anywhere in the system. It was found that the DSOG reduced the number of structures overtopped during probable maximum flood from thirteen to four, while the number of structures that could fail would be reduced from seven to two. 8 refs., 4 figs., 3 tabs

  17. Near-IR Spectral Imaging of Semiconductor Absorption Sites in Integrated Circuits

    Directory of Open Access Journals (Sweden)

    E. C. Samson

    2004-12-01

    Full Text Available We derive spectral maps of absorption sites in integrated circuits (ICs by varying the wavelength of the optical probe within the near-IR range. This method has allowed us to improve the contrast of the acquired images by revealing structures that have a different optical absorption from neighboring sites. A false color composite image from those acquired at different wavelengths is generated from which the response of each semiconductor structure can be deduced. With the aid of the spectral maps, nonuniform absorption was also observed in a semiconductor structure located near an electrical overstress defect. This method may prove important in failure analysis of ICs by uncovering areas exhibiting anomalous absorption, which could improve localization of defective edifices in the semiconductor parts of the microchip

  18. Operative Duration and Risk of Surgical Site Infection in Neurosurgery.

    Science.gov (United States)

    Bekelis, Kimon; Coy, Shannon; Simmons, Nathan

    2016-10-01

    The association of surgical duration with the risk of surgical site infection (SSI) has not been quantified in neurosurgery. We investigated the association of operative duration in neurosurgical procedures with the incidence of SSI. We performed a retrospective cohort study involving patients who underwent neurosurgical procedures from 2005 to 2012 and were registered in the American College of Surgeons National Quality Improvement Project registry. To control for confounding, we used multivariable regression models and propensity score conditioning. During the study period there were 94,744 patients who underwent a neurosurgical procedure and met the inclusion criteria. Of these patients, 4.1% developed a postoperative SSI within 30 days. Multivariable logistic regression showed an association between longer operative duration with higher incidence of SSI (odds ratio [OR], 1.18; 95% confidence interval [CI], 1.16-1.20). Compared with procedures of moderate duration (third quintile, 40th-60th percentile), patients undergoing the longest procedures (>80th percentile) had higher odds (OR, 2.07; 95% CI, 1.86-2.31) of developing SSI. The shortest procedures (operative duration was associated with increased incidence of SSI for neurosurgical procedures. These results can be used by neurosurgeons to inform operative management and to stratify patients with regard to SSI risk. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Benefit Opportunities for Integrated Surface and Airspace Departure Scheduling: A Study of Operations at Charlotte-Douglas International Airport

    Science.gov (United States)

    Coppenbarger, Rich; Jung, Yoon; Kozon, Tom; Farrahi, Amir; Malik, Wakar; Lee, Hanbong; Chevalley, Eric; Kistler, Matt

    2016-01-01

    NASA is collaborating with the FAA and aviation industry to develop and demonstrate new capabilities that integrate arrival, departure, and surface air-traffic operations. The concept relies on trajectory-based departure scheduling and collaborative decision making to reduce delays and uncertainties in taxi and climb operations. The paper describes the concept and benefit mechanisms aimed at improving flight efficiency and predictability while maintaining or improving operational throughput. The potential impact of the technology is studied and discussed through a quantitative analysis of relevant shortfalls at the site identified for initial deployment and demonstration in 2017: Charlotte-Douglas International Airport. Results from trajectory analysis indicate substantial opportunity to reduce taxi delays for both departures and arrivals by metering departures at the gate in a manner that maximizes throughput while adhering to takeoff restrictions due mostly to airspace constraints. Substantial taxi-out delay reduction is shown for flights subject to departure restrictions stemming from traffic flow management initiatives. Opportunities to improve the predictability of taxi, takeoff, and climb operations are examined and their potential impact on airline scheduling decisions and air-traffic forecasting is discussed. In addition, the potential to improve throughput with departure scheduling that maximizes use of available runway and airspace capacity is analyzed.

  20. Final environmental impact statement for the Nevada Test Site and off-site locations in the State of Nevada. Summary

    International Nuclear Information System (INIS)

    1996-08-01

    This sitewide EIS evaluates the potential environmental impacts of four possible land-use alternatives being considered for the Nevada Test Site (NTS), the Tonopah Test Range, and the formerly operated DOE sites in the state of Nevada: the Project Shoal Area, the Central Nevada Test Area, and portions of the Nellis Air Force Range Complex. Three additional sites in Nevada-Eldorado Valley, Dry Lake Valley, and Coyote Spring Valley-are evaluated for collocation of solar energy production facilities. The four alternatives include Continue Current Operations (No Action, continue to operate at the level maintained for the past 3 to 5 years); Discontinue Operations 1 (discontinue operations and interagency programs); Expanded Use (increased use of NTS and its resources to support defense and nondefense programs); and Alternate Use of Withdrawn Lands (discontinue all defense-related activities at NTS; continue waste management operations in support of NTS environmental restoration efforts; expand nondefense research). Environmental impacts were assessed for each alternative by analyzing, to the extent possible, the discrete and cumulative environmental impacts associated with Defense Waste Management, Environmental Restoration, Nondefense Research and Development, and Work for Others Programs. A framework for a Resource Management Plan is included as Volume 2 of this EIS and represents the development of an ecosystem based planning process closely integrated with the National Environmental Policy Act process. This EIS, among other things, analyzed the impacts of transportation of low level waste, and site characterization activities related to the Yucca Mountain Project but did not analyze the suitability of the site as a repository. This EIS does not analyze the suitability of the Yucca Mountain site as a repository as this is an action beyond the scope of the EIS. Volume 3 of this EIS contains the public comments and the responses to the comments

  1. Characterization of Salmonella spp. isolated from an integrated broiler chicken operation in Korea.

    Science.gov (United States)

    Lee, Young Ju; Kim, Hyun Jung; Park, Cheong Kyu; Kim, Ki Seuk; Bae, Dong Hwa; Kang, Min Su; Cho, Jae Keun; Kim, Ae Ran; Kim, Jong Wan; Kim, Byoung Han

    2007-04-01

    The purpose of this study was to investigate the biological and genetic characterization of persistent Salmonella isolates in an integrated broiler chicken operation, in an attempt to elucidate the source of contamination. From the breeder farm, the hatchery, the broiler farm and the chicken slaughter house of an integrated broiler chicken operation, a total of 6 serotypes were observed. Although S. Heidelberg was not detected in the broiler farm, it was consistently found in the breeder farm, the hatchery and the chicken slaughter house. Also, S. Enteritidis and S. Senftenberg were found in the hatchery and the chicken slaughter house, and the hatchery and the broiler farm, respectively. S. Gallinarum and S. Blockley were found only in the broiler farm, and S. Virchow was only recovered in the chicken slaughter house. Isolated S. Heidelberg, S. Enteritidis and S. Senftenberg strains were divided into 3, 5 and 7 types, respectively, on the basis of all properties. Especially, S. Senftenberg isolates, divided into four types by their antimicrobial resistance patterns, were all obviously the XbaI PFGE pattern. Also, four S. Enteritidis isolates resistant to nalidixic acid showed a difference in phage type and PFGE pattern. Such a different pattern was shown despite Salmonella isolates originating from an integrated broiler operation, suggesting that further epidemiological studies on many integrated chicken companies in Korea are needed.

  2. Review on Malaysian Rail Transit Operation and Management System: Issues and Solution in Integration

    Science.gov (United States)

    Masirin, Mohd Idrus Mohd; Salin, Aminah Mohd; Zainorabidin, Adnan; Martin, David; Samsuddin, Norshakina

    2017-08-01

    In any context, operation and management of transportation systems are key issues which may affect both life quality and economic development. In large urban agglomerations, an efficient public transportation system may help abate the negative externalities of private car use such as congestion, air and noise pollution, accident and fuel consumption, without excessively penalizing user travel times or zone accessibility. Thus, this study is conducted to appraise the Malaysian rural rail transit operation and management system, which are considered important as there are many issues and solution in integration of the services that need to be tackled more conscientiously. The purpose of this paper is to describe some of the most important issues on integration of services and rail transit system in Malaysian and how to solve or reduce these problems and conflicts. In this paper, it consists of the historical development of rail transit construction in Malaysia. This paper also attempts to identify the important issues related to rail transit services and integration in Malaysian rural rail operation and management system. Comparison is also conducted with other countries such as UK, France, and Japan. Finally, a critical analysis is presented in this paper by looking at the possible application for future Malaysian rail transit operation system and management, especially focusing on enhancing the quality of Malaysian rural rail transit. In conclusion, this paper is expected to successfully review and appraise the existing Malaysian rural rail transit operation and management system pertaining to issues & solution in integration. It is also hoped that reformation or transformation of present service delivery quality of the rail transit operation and management will enable Malaysia to succeed in transforming Malaysian transportation system to greater heights.

  3. Integrating intrusive and nonintrusive characterization methods to achieve a conceptual site model for the SLDA FUSRAP site

    International Nuclear Information System (INIS)

    Durham, L.A.; Peterson, J.M.; Frothingham, D.G.; Frederick, W.T.; Lenart, W.

    2008-01-01

    The US Army Corps of Engineers (USACE) is addressing radiological contamination following Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) requirements at the Shallow Land Disposal Area (SLDA) site, which is a radiologically contaminated property that is part of the Formerly utilized Sites Remedial Action Program (FUSRAP). The SLDA is an 18-hectare (44-acre) site in Parks township, Armstrong County, Pennsylvania, about 37 kilometers (23 miles) east-northeast of Pittsburgh. According to historical record, radioactive wastes were disposed of at the SLDA in a series of trenches by the Nuclear Materials and Equipment Company (NUMEC) in the 1960s. The wastes originated from the nearby Apollo nuclear fuel fabrication facility, which began operations under NUMEC in the late 1950s and fabricated enriched uranium into naval reactor fuel elements. It is believed that the waste materials were buried in a series of pits constructed adjacent to one another in accordance with an Atomic Energy Commission (AEC) regulation that has since been rescinded. A CERCLA remedial investigation/feasibility study (RI/FS) process was completed for the SLDA site, and the results of the human health risk assessment indicated that the radiologically contaminated wastes could pose a risk to human health in the future. There are no historical records that provide the exact location of these pits. However, based on geophysical survey results conducted in the 1980s, these pits were defined by geophysical anomalies and were depicted on historical site drawings as trenches. At the SLDA site, a combination of investigative methods and tools was used in the RI/FS and site characterization activities. The SLDA site provides an excellent example of how historical documents and data, historical aerial photo analysis, physical sampling, and nonintrusive geophysical and gamma walkover surveys were used in combination to reduce the uncertainty in the location of the trenches. The

  4. Integrating women into operator type work at N Reactor Plant

    International Nuclear Information System (INIS)

    Vinther, A.P.

    1976-01-01

    The Affirmative Action Plan in place at the Hanford complex has the goal of filling jobs in all phases of the work force with qualified minority personnel. The paper deals with the special concern, adjustments, and results achieved within UNI as a result of integrating qualified women candidates into the operator and technologist training program

  5. Integrated ground-water monitoring strategy for NRC-licensed facilities and sites: Case study applications

    Science.gov (United States)

    Price, V.; Temples, T.; Hodges, R.; Dai, Z.; Watkins, D.; Imrich, J.

    2007-01-01

    This document discusses results of applying the Integrated Ground-Water Monitoring Strategy (the Strategy) to actual waste sites using existing field characterization and monitoring data. The Strategy is a systematic approach to dealing with complex sites. Application of such a systematic approach will reduce uncertainty associated with site analysis, and therefore uncertainty associated with management decisions about a site. The Strategy can be used to guide the development of a ground-water monitoring program or to review an existing one. The sites selected for study fall within a wide range of geologic and climatic settings, waste compositions, and site design characteristics and represent realistic cases that might be encountered by the NRC. No one case study illustrates a comprehensive application of the Strategy using all available site data. Rather, within each case study we focus on certain aspects of the Strategy, to illustrate concepts that can be applied generically to all sites. The test sites selected include:Charleston, South Carolina, Naval Weapons Station,Brookhaven National Laboratory on Long Island, New York,The USGS Amargosa Desert Research Site in Nevada,Rocky Flats in Colorado,C-Area at the Savannah River Site in South Carolina, andThe Hanford 300 Area.A Data Analysis section provides examples of detailed data analysis of monitoring data.

  6. RCRA facility investigation/corrective measures study work plan for the 100-DR-1 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et. al. 1990a), signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1,000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste, and other CERCLA hazardous substances. Also included in the Tri-Party Agreement are 55 Resource Conservation and Recovery Act (RCRA) treatment, storage, or disposal (TSD) facilities that will be closed or permitted to operate in accordance with RCRA regulations. Some of the TSD facilities are included in the operable units. This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the RCRA facility investigation/corrective measures study (RFI/CMS) for the 100-DR-1 source operable unit Source operable units include facilities and unplanned release sites that are potential sources of contamination

  7. U.S. Department of Energy, Nevada Operations Office, environmental data report for the Nevada Test Site -- 1995

    Energy Technology Data Exchange (ETDEWEB)

    Black, S.C.; Townsend, Y.E. [eds.; Kinnison, R.R.

    1997-10-01

    The US Department of Energy (DOE) Order 5400.1, ``General Environmental Protection Program,`` establishes environmental protection program requirements, authorities, and responsibilities for DOE operations. These mandates require compliance with applicable federal, state, and local environmental protection regulations. During calendar year (CY) 1995 environmental protection and monitoring programs were conducted at the Nevada Test Site (NTS) and other DOE Nevada Operations Office (DOE/NV) managed sites in Nevada and across the United States. A detailed discussion of these environmental protection and monitoring programs, and summary data and assessments for environmental monitoring results at these sites in CY 1995 are provided in the DOE/NV, Annual Site Environmental Report--1995, (ASER) DOE/NV/11718-037. A brief description of the scope of this environmental monitoring is provided below, categorized by ``on-NTS`` and ``off-NTS`` monitoring.

  8. Identification of operator sites of the CI repressor of phage TP901-1: evolutionary link to other phages

    International Nuclear Information System (INIS)

    Johansen, Annette H.; Broendsted, Lone; Hammer, Karin

    2003-01-01

    The repressor encoded by the cI gene of the temperate Lactococcus lactis subsp. cremoris bacteriophage TP901-1 has been purified. Gel-retardation and footprinting analyses identified three palindromic operator sites (O R , O L , and O D ). The operator site O R is located between the two divergent early promoters P R and P L , O L overlaps the transcriptional start of the lytic P L promoter, and O D is located downstream of the mor gene, the first gene in the lytic gene cluster. The function of O L was verified by mutational analysis. Binding was found to be specific and cooperative. Multimeric forms of the repressor were observed, thus indicating that the repressor may bind simultaneously to all three operator sites. Inverted repeats with homology to the operator sites of TP901-1 were identified in phage genomes encoding repressors homologous to CI of TP901-1. Interestingly, the locations of these repeats on the phage genomes correspond to those found in TP901-1, indicating that the same system of cooperative repression of early phage promoters has been inherited by modular evolution

  9. Operations and Maintenance Manual for Expanded Bioventing System Site FC-2 Kelly AFB, Texas

    National Research Council Canada - National Science Library

    1996-01-01

    This Operations and Maintenance Manual has been created as a guide for monitoring and maintaining the performance of the bioventing blower and vent well plumbing at the Fire Training Area (Site FC-2...

  10. D Integrated Methodologies for the Documentation and the Virtual Reconstruction of AN Archaeological Site

    Science.gov (United States)

    Balletti, C.; Guerra, F.; Scocca, V.; Gottardi, C.

    2015-02-01

    Highly accurate documentation and 3D reconstructions are fundamental for analyses and further interpretations in archaeology. In the last years the integrated digital survey (ground-based survey methods and UAV photogrammetry) has confirmed its main role in the documentation and comprehension of excavation contexts, thanks to instrumental and methodological development concerning the on site data acquisition. The specific aim of the project, reported in this paper and realized by the Laboratory of Photogrammetry of the IUAV University of Venice, is to check different acquisition systems and their effectiveness test, considering each methodology individually or integrated. This research focuses on the awareness that the integration of different survey's methodologies can as a matter of fact increase the representative efficacy of the final representations; these are based on a wider and verified set of georeferenced metric data. Particularly the methods' integration allows reducing or neutralizing issues related to composite and complex objects' survey, since the most appropriate tools and techniques can be chosen considering the characteristics of each part of an archaeological site (i.e. urban structures, architectural monuments, small findings). This paper describes the experience in several sites of the municipality of Sepino (Molise, Italy), where the 3d digital acquisition of cities and structure of monuments, sometimes hard to reach, was realized using active and passive techniques (rage-based and image based methods). This acquisition was planned in order to obtain not only the basic support for interpretation analysis, but also to achieve models of the actual state of conservation of the site on which some reconstructive hypotheses can be based on. Laser scanning data were merged with Structure from Motion techniques' clouds into the same reference system, given by a topographical and GPS survey. These 3d models are not only the final results of the metric

  11. Integral-Type Operators from Bloch-Type Spaces to QK Spaces

    Directory of Open Access Journals (Sweden)

    Stevo Stević

    2011-01-01

    Full Text Available The boundedness and compactness of the integral-type operator Iφ,g(nf(z=∫0zf(n(φ(ζg(ζdζ, where n∈N0, φ is a holomorphic self-map of the unit disk D, and g is a holomorphic function on D, from α-Bloch spaces to QK spaces are characterized.

  12. Integration of a browser based operator manual in the system environment of a process computer system; Integration eines browserbasierten Betriebshandbuchs in die Systemumgebung einer Prozessrechneranlage

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Andreas [Westinghouse Electric Germany GmbH (Germany); Erfle, Robert [DOSCO GmbH, Heidelberg (Germany); Feinkohl, Dirk [E.ON Kernkraft GmbH (Germany). Kernkraftwerk Unterweser

    2012-11-01

    The integration of a browser based operator manual in the system environment of a process computer system is an optimization of the operating procedure in the control room and a safety enhancement due to faster and error-free access to the manual contents. Several requirements by the authorities have to be fulfilled: the operating manual has to be available as hard copy, the format has to be true to original, protection against manipulation has to be provided, the manual content of the browser-based version and the hard copy have to identical, and the display presentation has to be consistent with ergonomic principals. The integration of the on-line manual in the surveillance process computer system provides the operator with the relevant comments to the surveillance signal. The described integration of the on-line manual is an optimization of the operator's everyday job with respect to ergonomics and safety (human performance).

  13. Integrative Analysis of CRISPR/Cas9 Target Sites in the Human HBB Gene

    Directory of Open Access Journals (Sweden)

    Yumei Luo

    2015-01-01

    Full Text Available Recently, the clustered regularly interspaced short palindromic repeats (CRISPR system has emerged as a powerful customizable artificial nuclease to facilitate precise genetic correction for tissue regeneration and isogenic disease modeling. However, previous studies reported substantial off-target activities of CRISPR system in human cells, and the enormous putative off-target sites are labor-intensive to be validated experimentally, thus motivating bioinformatics methods for rational design of CRISPR system and prediction of its potential off-target effects. Here, we describe an integrative analytical process to identify specific CRISPR target sites in the human β-globin gene (HBB and predict their off-target effects. Our method includes off-target analysis in both coding and noncoding regions, which was neglected by previous studies. It was found that the CRISPR target sites in the introns have fewer off-target sites in the coding regions than those in the exons. Remarkably, target sites containing certain transcriptional factor motif have enriched binding sites of relevant transcriptional factor in their off-target sets. We also found that the intron sites have fewer SNPs, which leads to less variation of CRISPR efficiency in different individuals during clinical applications. Our studies provide a standard analytical procedure to select specific CRISPR targets for genetic correction.

  14. Integration of aerial imaging and variable-rate technology for site-specific aerial herbicide application

    Science.gov (United States)

    As remote sensing and variable rate technology are becoming more available for aerial applicators, practical methodologies on effective integration of these technologies are needed for site-specific aerial applications of crop production and protection materials. The objectives of this study were to...

  15. Monticello Mill Tailings Site, Operable Unit lll, Annual Groundwater Report, May 2015 Through April 2016

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Jason [USDOE Office of Legacy Management (LM), Washington, DC (United States); Smith, Fred [Navarro Research and Engineering, Oak Ridge, TN (United States)

    2016-10-01

    This report provides the annual analysis of water quality restoration progress, cumulative through April 2016, for Operable Unit (OU) III, surface water and groundwater, of the U.S. Department of Energy (DOE) Office of Legacy Management (LM) Monticello Mill Tailings Site (MMTS). The MMTS is a Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List site located in and near the city of Monticello, San Juan County, Utah. MMTS comprises the 110-acre site of a former uranium- and vanadium-ore-processing mill (mill site) and 1700 acres of surrounding private and municipal property. Milling operations generated 2.5 million cubic yards of waste (tailings) from 1942 to 1960. The tailings were impounded at four locations on the mill site. Inorganic constituents in the tailings drained from the impoundments to contaminate local surface water (Montezuma Creek) and groundwater in the underlying alluvial aquifer. Mill tailings dispersed by wind and water also contaminated properties surrounding and downstream of the mill site. Remedial actions to remove and isolate radiologically contaminated soil, sediment, and debris from the former mill site, Operable Unit I (OU I), and surrounding properties (OU II) were completed in 1999 with the encapsulation of the wastes in an engineered repository located on DOE property 1 mile south of the former mill site. This effectively removed the primary source of groundwater contamination; however, contamination of groundwater and surface water remains within OU III at levels that exceed water quality protection standards. Uranium is the primary contaminant of concern (COC). LM implemented monitored natural attenuation with institutional controls as the OU III remedy in 2004. Because groundwater restoration proceeded more slowly than expected and did not meet performance criteria established in the OU III Record of Decision (June 2004), LM implemented a contingency action in 2009 by an Explanation of

  16. Background Information for the Nevada National Security Site Integrated Sampling Plan, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Farnham, Irene; Marutzky, Sam

    2014-12-01

    This document describes the process followed to develop the Nevada National Security Site (NNSS) Integrated Sampling Plan (referred to herein as the Plan). It provides the Plan’s purpose and objectives, and briefly describes the Underground Test Area (UGTA) Activity, including the conceptual model and regulatory requirements as they pertain to groundwater sampling. Background information on other NNSS groundwater monitoring programs—the Routine Radiological Environmental Monitoring Plan (RREMP) and Community Environmental Monitoring Program (CEMP)—and their integration with the Plan are presented. Descriptions of the evaluations, comments, and responses of two Sampling Plan topical committees are also included.

  17. The EuroSITES network: Integrating and enhancing fixed-point open ocean observatories around Europe

    Science.gov (United States)

    Lampitt, Richard S.; Larkin, Kate E.; EuroSITES Consortium

    2010-05-01

    EuroSITES is a 3 year (2008-2011) EU collaborative project (3.5MEuro) with the objective to integrate and enhance the nine existing open ocean fixed point observatories around Europe (www.eurosites.info). These observatories are primarily composed of full depth moorings and make multidisciplinary in situ observations within the water column as the European contribution to the global array OceanSITES (www.oceansites.org). In the first 18 months, all 9 observatories have been active and integration has been significant through the maintenance and enhancement of observatory hardware. Highlights include the enhancement of observatories with sensors to measure O2, pCO2, chlorophyll, and nitrate in near real-time from the upper 1000 m. In addition, some seafloor missions are also actively supported. These include seafloor platforms currently deployed in the Mediterranean, one for tsunami detection and one to monitor fluid flow related to seismic activity and slope stability. Upcoming seafloor science missions in 2010 include monitoring benthic biological communities and associated biogeochemistry as indicators of climate change in both the Northeast Atlantic and Mediterranean. EuroSITES also promotes the development of innovative sensors and samplers in order to progress capability to measure climate-relevant properties of the ocean. These include further developing current technologies for autonomous long-term monitoring of oxygen consumption in the mesopelagic, pH and mesozooplankton abundance. Many of these science missions are directly related to complementary activities in other European projects such as EPOCA, HYPOX and ESONET. In 2010 a direct collaboration including in situ field work will take place between ESONET and EuroSITES. The demonstration mission MODOO (funded by ESONET) will be implemented in 2010 at the EuroSITES PAP observatory. Field work will include deployment of a seafloor lander system with various sensors which will send data to shore in real

  18. Groundwater/Vadose Zone Integration Project Management Plan

    International Nuclear Information System (INIS)

    Hughes, M. C.

    1999-01-01

    This Project Management Plan (PMP) defines the authorities, roles, and responsibilities of the US Department of Energy (DOE), Richland Operations Office (RL) and those contractor organizations participating in the Hanford Site' s Groundwater/Vadose Zone (GW/VZ) Integration Project. The PMP also describes the planning and control systems, business processes, and other management tools needed to properly and consistently conduct the Integration Project scope of work

  19. Rapid development of stable transgene CHO cell lines by CRISPR/Cas9-mediated site-specific integration into C12orf35.

    Science.gov (United States)

    Zhao, Menglin; Wang, Jiaxian; Luo, Manyu; Luo, Han; Zhao, Meiqi; Han, Lei; Zhang, Mengxiao; Yang, Hui; Xie, Yueqing; Jiang, Hua; Feng, Lei; Lu, Huili; Zhu, Jianwei

    2018-07-01

    Chinese hamster ovary (CHO) cells are the most widely used mammalian hosts for recombinant protein production. However, by conventional random integration strategy, development of a high-expressing and stable recombinant CHO cell line has always been a difficult task due to the heterogenic insertion and its caused requirement of multiple rounds of selection. Site-specific integration of transgenes into CHO hot spots is an ideal strategy to overcome these challenges since it can generate isogenic cell lines with consistent productivity and stability. In this study, we investigated three sites with potential high transcriptional activities: C12orf35, HPRT, and GRIK1, to determine the possible transcriptional hot spots in CHO cells, and further construct a reliable site-specific integration strategy to develop recombinant cell lines efficiently. Genes encoding representative proteins mCherry and anti-PD1 monoclonal antibody were targeted into these three loci respectively through CRISPR/Cas9 technology. Stable cell lines were generated successfully after a single round of selection. In comparison with a random integration control, all the targeted integration cell lines showed higher productivity, among which C12orf35 locus was the most advantageous in both productivity and cell line stability. Binding affinity and N-glycan analysis of the antibody revealed that all batches of product were of similar quality independent on integrated sites. Deep sequencing demonstrated that there was low level of off-target mutations caused by CRISPR/Cas9, but none of them contributed to the development process of transgene cell lines. Our results demonstrated the feasibility of C12orf35 as the target site for exogenous gene integration, and strongly suggested that C12orf35 targeted integration mediated by CRISPR/Cas9 is a reliable strategy for the rapid development of recombinant CHO cell lines.

  20. Archive of Core and Site/Hole Data and Photographs from the Integrated Ocean Drilling Program (IODP)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The US Science Operator for the Integrated Ocean Drilling Program (IODP) operated the drilling vessel JOIDES Resolution from 2004-2013 for worldwide expeditions...

  1. Preliminary investigation Area 12 fleet operations steam cleaning discharge area Nevada Test Site

    International Nuclear Information System (INIS)

    1996-07-01

    This report documents the characterization activities and findings of a former steam cleaning discharge area at the Nevada Test Site. The former steam cleaning site is located in Area 12 east of Fleet Operations Building 12-16. The characterization project was completed as a required condition of the ''Temporary Water Pollution Control Permit for the Discharge From Fleet Operations Steam Cleaning Facility'' issued by the Nevada Division of Environmental Protection. The project objective was to collect shallow soil samples in eight locations in the former surface discharge area. Based upon field observations, twelve locations were sampled on September 6, 1995 to better define the area of potential impact. Samples were collected from the surface to a depth of approximately 0.3 meters (one foot) below land surface. Discoloration of the surface soil was observed in the area of the discharge pipe and in localized areas in the natural drainage channel. The discoloration appeared to be consistent with the topographically low areas of the site. Hydrocarbon odors were noted in the areas of discoloration only. Samples collected were analyzed for bulk asbestos, Toxicity Characteristic Leaching Procedure (TCLP) metals, total petroleum hydrocarbons (TPHs), volatile organic compounds (VOCs), semi-volatile organic compounds (Semi-VOCs), and gamma scan

  2. Prolonged Operative Duration Increases Risk of Surgical Site Infections: A Systematic Review.

    Science.gov (United States)

    Cheng, Hang; Chen, Brian Po-Han; Soleas, Ireena M; Ferko, Nicole C; Cameron, Chris G; Hinoul, Piet

    The incidence of surgical site infection (SSI) across surgical procedures, specialties, and conditions is reported to vary from 0.1% to 50%. Operative duration is often cited as an independent and potentially modifiable risk factor for SSI. The objective of this systematic review was to provide an in-depth understanding of the relation between operating time and SSI. This review included 81 prospective and retrospective studies. Along with study design, likelihood of SSI, mean operative times, time thresholds, effect measures, confidence intervals, and p values were extracted. Three meta-analyses were conducted, whereby odds ratios were pooled by hourly operative time thresholds, increments of increasing operative time, and surgical specialty. Pooled analyses demonstrated that the association between extended operative time and SSI typically remained statistically significant, with close to twice the likelihood of SSI observed across various time thresholds. The likelihood of SSI increased with increasing time increments; for example, a 13%, 17%, and 37% increased likelihood for every 15 min, 30 min, and 60 min of surgery, respectively. On average, across various procedures, the mean operative time was approximately 30 min longer in patients with SSIs compared with those patients without. Prolonged operative time can increase the risk of SSI. Given the importance of SSIs on patient outcomes and health care economics, hospitals should focus efforts to reduce operative time.

  3. RCRA facility investigation/corrective measures study work plan for the 100-HR-3 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-09-01

    Four areas of the Hanford Site (the 100, 200, 300, and 1100 Areas) have been included on the US Environmental Protection Agency's (EPA's) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under the Hanford Federal Facility Agreement and Consent Order, signed by the Washington State Department of Ecology (Ecology), EPA, and the US Department of Energy (DOE), more than 1000 inactive waste disposal and unplanned release sites on the Hanford Site have been grouped into a number of source and groundwater operable units. These operable units contain contamination in the form of hazardous waste, radioactive/hazardous mixed waste, and other CERCLA hazardous substances. Also included in the Tri-Party Agreement are 55 Resource Conservation and Recovery Act (RCRA) treatment, storage, or disposal (TSD) facilities that will be closed or permitted to operate in accordance with RCRA regulations, under the authority of Chapter 173-303 Washington Administrative Code (WAC). Some of the TSD facilities are included in the operable units. This work plan and the attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the RCRA facility investigation/corrective measures study (RFI/CMS) for the 100-HR-3 operable unit. The 100-HR-3 operable unit underlies the D/DR and H Areas, the 600 Area between them, and the six source operable units these areas contain. The 100-HR-3 operable unit includes all contamination found in the aquifer soils and water within its boundary. Source operable units include facilities and unplanned release sites that are potential sources of contamination. Separate work plans have been initiated for the 100-DR-1 (DOE-RL 1992a) and 100-HR-1 (DOE-RL 1992b) source operable units

  4. Integration of CERCLA and RCRA requirements at the Radioactive Waste Burial Grounds, Savannah River Site, Aiken, South Carolina

    International Nuclear Information System (INIS)

    Hoffman, W.D.; Wyatt, D.E.

    1992-01-01

    The purpose of this paper to is present the comprehensive approach being taken at the Savannah River Site (SRS) to consolidate regulatory documents, characterization and assessment activities for 3 contiguous waste management facilities. These facilities cover 7.12 x 10 5 m 2 (194 acres) and include an Old Radioactive Waste Burial Ground, a Low Level Radioactive Waste Disposal Facility, and a closed Mixed Waste Management Facility. Each of these facilities include one or more operable units including solvent tanks, transuranic waste storage pads, research lysimeters and experimental confinement disposal vaults. All of these facilities have differing submittal dates for regulatory documents but similar and continuous environmental problems. The characterization and risk assessment require simultaneous efforts for all facilities to adequately define the nature and extent of past, present and future environmental impact. Current data indicates that contaminant plumes in both soil and water are comingled, interspersed and possibly exist internally within the contiguous facilities, requiring a combined investigative effort. This paper describes the combination of regulatory documents leading to this comprehensive and integrative approach for burial ground characterization at the Savannah River Site

  5. Using Distributed Operations to Enable Science Research on the International Space Station

    Science.gov (United States)

    Bathew, Ann S.; Dudley, Stephanie R. B.; Lochmaier, Geoff D.; Rodriquez, Rick C.; Simpson, Donna

    2011-01-01

    In the early days of the International Space Station (ISS) program, and as the organization structure was being internationally agreed upon and documented, one of the principal tenets of the science program was to allow customer-friendly operations. One important aspect of this was to allow payload developers and principle investigators the flexibility to operate their experiments from either their home sites or distributed telescience centers. This telescience concept was developed such that investigators had several options for ISS utilization support. They could operate from their home site, the closest telescience center, or use the payload operations facilities at the Marshall Space Flight Center in Huntsville, Alabama. The Payload Operations Integration Center (POIC) processes and structures were put into place to allow these different options to its customers, while at the same time maintain its centralized authority over NASA payload operations and integration. For a long duration space program with many scientists, researchers, and universities expected to participate, it was imperative that the program structure be in place to successfully facilitate this concept of telescience support. From a payload control center perspective, payload science operations require two major elements in order to make telescience successful within the scope of the ISS program. The first element is decentralized control which allows the remote participants the freedom and flexibility to operate their payloads within their scope of authority. The second element is a strong ground infrastructure, which includes voice communications, video, telemetry, and commanding between the POIC and the payload remote site. Both of these elements are important to telescience success, and both must be balanced by the ISS program s documented requirements for POIC to maintain its authority as an integration and control center. This paper describes both elements of distributed payload

  6. Compliance with Operational Circular No. 2 on conditions of access to the fenced CERN sites

    CERN Multimedia

    Relations with the Host States Service

    2004-01-01

    The purpose of Operational Circular No. 2 is to contribute to the protection of people and property by defining the conditions of access to the Organization's fenced sites. However, recently, the services concerned have noted a significant increase in the instances of non-compliance with those conditions that cannot be tolerated, for example: use of CERN access cards by people, other than the cardholders themselves, in order to gain access to facilities without having attended the required safety course; speeding, particularly on Route Gregory and Route Weisskopf; driving in and out of the site on the wrong side of the road; parking on spaces set aside for the disabled; nuisance parking, especially in the proximity of the Restaurants; the dumping of wrecked vehicles. As the aforementioned instances of non-compliance can lead to dangerous situations, the Organization reserves the right to apply the penalties provided for under paragraph 26 of Operational Circular No. 2, namely to refuse access to the site...

  7. Migration of the Almaraz NPP integrated operation management system to a new computer platform

    International Nuclear Information System (INIS)

    Gonzalez Crego, E.; Martin Lopez-Suevos, C.

    1996-01-01

    In all power plants, it becomes necessary, with the passage of time, to migrate the initial operation management systems to adapt them to current technologies. That is a good time to improve the inclusion of data in the corporative database and standardize the system interfaces and operation, whilst maintaining data system operability. This article contains Almaraz experience in migrating its Integrated Operation Management System to an advanced computer platform based on open systems (UNIX), communications network (ETHERNET) and database (ORACLE). To this effect, clear objectives and strict standards were established to facilitate the work. The most noteworthy results obtained are: Better quality of information and structure in the corporative database Standardised user interface in all applications. Joint migration of applications for Maintenance, Components and Spare parts, Warehouses and Purchases. Integration of new applications into the system. Introduction of the navigator, which allows movement around the database using all available applications. (Author)

  8. Site organization and site arrangement

    International Nuclear Information System (INIS)

    Boissonnet, B.; Macqueron, J.F.

    1976-01-01

    The present paper deals with criteria for the choice of a production unit or power plant site, the organization and development of a site in terms of its particular characteristics and takes into account personnel considerations in site organizations as well as the problem of integrating the architecture into the environment. (RW) [de

  9. Integrated monitoring of multi-domain backbone connections Operational experience in the LHC optical private network

    CERN Document Server

    Marcu, Patricia; Fritz, Wolfgang; Yampolskiy, Mark; Hommel, Wolfgang

    2011-01-01

    Novel large scale research projects often require cooperation between various different project partners that are spread among the entire world. They do not only need huge computing resources, but also a reliable network to operate on. The Large Hadron Collider (LHC) at CERN is a representative example for such a project. Its experiments result in a vast amount of data, which is interesting for researchers around the world. For transporting the data from CERN to 11 data processing and storage sites, an optical private network (OPN) has been constructed. As the experiment data is highly valuable, LHC defines very high requirements to the underlying network infrastructure. In order to fulfil those requirements, the connections have to be managed and monitored permanently. In this paper, we present the integrated monitoring solution developed for the LHCOPN. We first outline the requirements and show how they are met on the single network layers. After that, we describe, how those single measurements can be comb...

  10. Integrated test plan for crosswell compressional and shear wave seismic tomography for site characterization at the VOC Arid Site

    International Nuclear Information System (INIS)

    Elbring, G.J.; Narbutovskih, S.M.

    1994-01-01

    This integrated test plan describes the demonstration of the crosswell acoustic tomography technique as part of the Volatile Organic Compounds-Arid Integrated Demonstration (VOC-Arid ID). The purpose of this demonstration is to image the subsurface seismic velocity structure and to relate the resulting velocity model to lithology and saturation. In fiscal year (FY) 1994 an initial fielding will test three different downhole sources at two different sites at the Hanford US Department of Energy facility to identify which sources will provide the energy required to propagate between existing steel-cased wells at these two sites. Once this has been established, a second fielding will perform a full compressional and shear wave tomographic survey at the most favorable site. Data reduction, analysis, and interpretation of this full data set will be completed by the end of this fiscal year. Data collection for a second survey will be completed by the end of the fiscal year, and data reduction for this data set will be completed in FY 1995. The specific need is detailed subsurface characterization with minimum intrusion. This technique also has applications for long term vadose zone monitoring for both Resource Conservation and Recovery Act (RCRA) waste storage facilities and for remediation monitoring. Images produced are continuous between boreholes. This is a significant improvement over the single point data derived solely from core information. Saturation changes, either naturally occurring (e.g., perched water tables) or remediation induced (e.g., water table mounding from injection wells or during inwell air sparging) could be imaged. These crosswell data allow optimal borehole placement for groundwater remediation, associated monitoring wells and possibly evaluation of the effective influence of a particular remediation technique

  11. Risk factors for deep surgical site infection following operative treatment of ankle fractures.

    Science.gov (United States)

    Ovaska, Mikko T; Mäkinen, Tatu J; Madanat, Rami; Huotari, Kaisa; Vahlberg, Tero; Hirvensalo, Eero; Lindahl, Jan

    2013-02-20

    Surgical site infection is one of the most common complications following ankle fracture surgery. These infections are associated with substantial morbidity and lead to increased resource utilization. Identification of risk factors is crucial for developing strategies to prevent these complications. We performed an age and sex-matched case-control study to identify patient and surgery-related risk factors for deep surgical site infection following operative ankle fracture treatment. We identified 1923 ankle fracture operations performed in 1915 patients from 2006 through 2009. A total of 131 patients with deep infection were identified and compared with an equal number of uninfected control patients. Risk factors for infection were determined with use of conditional logistic regression analysis. The incidence of deep infection was 6.8%. Univariate analysis showed diabetes (odds ratio [OR] = 2.2, 95% confidence interval [CI] = 1.0, 4.9), alcohol abuse (OR = 3.8, 95% CI = 1.6, 9.4), fracture-dislocation (OR = 2.0, 95% CI = 1.2, 3.5), and soft-tissue injury (a Tscherne grade of ≥1) (OR = 2.6, 95% CI = 1.3, 5.3) to be significant patient-related risk factors for infection. Surgery-related risk factors were suboptimal timing of prophylactic antibiotics (OR = 1.9, 95% CI = 1.0, 3.4), difficulties encountered during surgery, (OR = 2.1, 95% CI = 1.1, 4.0), wound complications (OR = 4.8, 95% CI = 1.6, 14.0), and fracture malreduction (OR = 3.4, 95% CI = 1.3, 9.2). Independent risk factors for infection identified by multivariable analyses were tobacco use (OR = 3.7, 95% CI = 1.6, 8.5) and a duration of surgery of more than ninety minutes (OR = 2.5, 95% CI = 1.1, 5.7). Cast application in the operating room was independently associated with a decreased infection rate (OR = 0.4, 95% CI = 0.2, 0.8). We identified several modifiable risk factors for deep surgical site infection following operative treatment of ankle fractures.

  12. 76 FR 63941 - Agency Information Collection Activities: Business Transformation-Automated Integrated Operating...

    Science.gov (United States)

    2011-10-14

    ... Activities: Business Transformation--Automated Integrated Operating Environment (IOE), New Information... Internet by federal agencies through efforts like USCIS' Business Transformation initiative. The USCIS ELIS... the USCIS Business Transformation initiative and wizard technology. The supporting statement can be...

  13. Environmental assessment for the expansion and operation of the Central Shops Borrow Pit at the Savannah River Site

    International Nuclear Information System (INIS)

    1997-03-01

    The Department of Energy (DOE) prepared this Environmental Assessment (EA) to assess the potential environmental impacts of the proposed expansion and operation of an existing borrow pit at the Savannah River Site (SRS), located near Aiken, South Carolina. A borrow pit is defined as an excavated area where material has been dug for use as fill at another location. The proposed action would entail the areal enlargement, continued operation, and eventual close-out of the established facility known as the Central Shops Borrow Pit. Operations at SRS supporting waste site closure and the construction and maintenance of site facilities and infrastructure require readily available suitable soil for use as fill material. With the recent depletion of the other existing on-site sources for such material, DOE proposes to expand the existing facility. The National Environmental Policy Act requires the assessment of environmental consequences of Federal actions that may affect the quality of the human environment. Based on the potential for impacts described herein, DOE will either publish a Finding of No Significant Impact or prepare an Environmental Impact Statement (EIS)

  14. NASA UAS Traffic Management National Campaign Operations across Six UAS Test Sites

    Science.gov (United States)

    Rios, Joseph; Mulfinger, Daniel; Homola, Jeff; Venkatesan, Priya

    2016-01-01

    NASA's Unmanned Aircraft Systems Traffic Management research aims to develop policies, procedures, requirements, and other artifacts to inform the implementation of a future system that enables small drones to access the low altitude airspace. In this endeavor, NASA conducted a geographically diverse flight test in conjunction with the FAA's six unmanned aircraft systems Test Sites. A control center at NASA Ames Research Center autonomously managed the airspace for all participants in eight states as they flew operations (both real and simulated). The system allowed for common situational awareness across all stakeholders, kept traffic procedurally separated, offered messages to inform the participants of activity relevant to their operations. Over the 3- hour test, 102 flight operations connected to the central research platform with 17 different vehicle types and 8 distinct software client implementations while seamlessly interacting with simulated traffic.

  15. Expected Future Conditions for Secure Power Operation with Large Scale of RES Integration

    International Nuclear Information System (INIS)

    Majstrovic, G.; Majstrovic, M.; Sutlovic, E.

    2015-01-01

    EU energy strategy is strongly focused on the large scale integration of renewable energy sources. The most dominant part here is taken by variable sources - wind power plants. Grid integration of intermittent sources along with keeping the system stable and secure is one of the biggest challenges for the TSOs. This part is often neglected by the energy policy makers, so this paper deals with expected future conditions for secure power system operation with large scale wind integration. It gives an overview of expected wind integration development in EU, as well as expected P/f regulation and control needs. The paper is concluded with several recommendations. (author).

  16. Integrated dry NO{sub x}/SO{sub 2} emissions control system: integrated system test report

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R.A.; Muzio, L.J. [Fossil Energy Research Corp., Laguna Hills, CA (United States); Hunt, T. [Public Service Co. of Colorado, Denver, CO (United States)

    1997-04-01

    The DOE sponsored Integrated Dry NO{sub x}/SO{sub 2} Emissions Control System Program, is a Clean Coal Technology III demonstration, being conducted by Public Service Company of Colorado. The test site is Arapahoe Generating Station Unit 4, a 100 MWe, down-fired utility boiler burning a low-sulfur Western coal. The project goal is to demonstrate up to 70 percent reductions in NO{sub x} and SO{sub 2} emissions through the integration of: (1) down-fired low NO{sub x} burners with overfire air; (2) Selective Non-Catalytic Reduction (SNCR) for additional NO{sub x} removal; and (3) Dry Sorbent Injection (DSI) and duct humidification for SO{sub 2} removal. This report documents the final phase of the test program, in which the overall performance of the integrated system was evaluated. Previous testing has shown that the goal of 70 percent NO{sub x} removal was easily achieved with the combination of low-NO{sub x} burners, overfire air, and urea-based SNCR. Similarly, the ability of the sodium-based DSI system to achieve 70 percent SO{sub 2} removal was also demonstrated previously. The integrated tests demonstrated the synergistic benefit of operating the SNCR and sodium-based DSI systems concurrently. With the automatic control system set to limit the NH{sub 3} emissions to less than 8 ppm, the NO{sub 2} emissions from the sodium-based DSI system were reduced by nominally 50 percent compared to operation with the DSI system alone. Comparably, the combined operation reduced NH{sub 3} emissions, as reflected by a higher urea injection rate for a fixed NH{sub 3} emission limit. With combined DSI and SNCR operation, an ammonia odor problem was encountered around the Unit 4 ash silo (this did not occur with the SNCR system operated alone at comparable NH{sub 3} slip levels). This odor problem is attributed to the sodium changing the rate at which NH{sub 3} is released from the ash when it is wetted for truck transport to the disposal site.

  17. Advanced Satellite Workstation - An integrated workstation environment for operational support of satellite system planning and analysis

    Science.gov (United States)

    Hamilton, Marvin J.; Sutton, Stewart A.

    A prototype integrated environment, the Advanced Satellite Workstation (ASW), which was developed and delivered for evaluation and operator feedback in an operational satellite control center, is described. The current ASW hardware consists of a Sun Workstation and Macintosh II Workstation connected via an ethernet Network Hardware and Software, Laser Disk System, Optical Storage System, and Telemetry Data File Interface. The central objective of ASW is to provide an intelligent decision support and training environment for operator/analysis of complex systems such as satellites. Compared to the many recent workstation implementations that incorporate graphical telemetry displays and expert systems, ASW provides a considerably broader look at intelligent, integrated environments for decision support, based on the premise that the central features of such an environment are intelligent data access and integrated toolsets.

  18. Operational Implementation of the MARSSIM Process at the Wayne Interim Storage Site

    International Nuclear Information System (INIS)

    Hays, D. C. Jr.; Trujillo, P. A. IV.; Zoller, S. G.

    2002-01-01

    This paper describes the methodologies behind the operational implementation of the Multi Agency Radiation Site Survey and Investigation Manual (MARSSIM) process at the Wayne Interim Storage Site (WISS). The United States Army Corps of Engineers (USACE) and Environmental Chemical Corporation (ECC) have implemented the MARSSIM process using various surveys producing raw data. The final remedial status of a survey unit is derived through data reduction, while maintaining a high degree of efficiency in the construction aspects of the remedial action. Data reduction of field measurements is accomplished by merging the data outputs of a Digital Global Positioning System, an exposure rate meter, and laboratory analyses to produce maps which present exposure rates, elevations, survey unit boundaries, direct measurement locations, and sampling locations on a single map. The map serves as a data-posting plot and allows the project team to easily judge the survey unit's remedial status. The operational implementation of the MARSSIM process has been successful in determining the eligibility of survey units for final status surveys at the WISS and also in demonstrating final status radiological and chemical conditions while maintaining an efficient remedial action effort

  19. From heat integration targets toward implementation – A TSA (total site analysis)-based design approach for heat recovery systems in industrial clusters

    International Nuclear Information System (INIS)

    Hackl, Roman; Harvey, Simon

    2015-01-01

    The European process industry is facing major challenges to decrease production costs. One strategy to achieve this is by increasing energy efficiency. Single chemical processes are often well-integrated and the tools to target and design such measures are well developed. Site-wide heat integration based on total site analysis tools can be used to identify opportunities to further increase energy efficiency. However, the methodology has to be developed further in order to enable identification of practical heat integration measures in a systematic way. Designing site-wide heat recovery systems across an industrial cluster is complex and involves aspects apart from thermal process and utility flows. This work presents a method for designing a roadmap of heat integration investments based on total site analysis. The method is applied to a chemical cluster in Sweden. The results of the case study show that application of the proposed method can achieve up to 42% of the previously targeted hot utility savings of 129 MW. A roadmap of heat integration systems is suggested, ranging from less complex systems that achieve a minor share of the heat recovery potential to sophisticated, strongly interdependent systems demanding large investments and a high level of collaboration. - Highlights: • Methodology focused on the practical implementation of site-wide heat recovery. • Algorithm to determine a roadmap of heat integration investments. • Case study: 42% hot utility savings potential at a pay-back period of 3.9y.

  20. Design and implementation of a computer based site operations log for the ARM Program

    International Nuclear Information System (INIS)

    Tichler, J.L.; Bernstein, H.J.; Bobrowski, S.F.; Melton, R.B.; Campbell, A.P.; Edwards, D.M.; Kanciruk, P.; Singley, P.T.

    1992-01-01

    The Atmospheric Radiation Measurement (ARM) Program is a Department of Energy (DOE) research effort to reduce the uncertainties found in general circulation and other models due to the effects of clouds and solar radiation. ARM will provide an experimental testbed for the study of important atmospheric effects, particularly cloud and radiative processes, and testing of parameterizations of the processes for use in atmospheric models. The design of the testbed known as the Clouds and Radiation Testbed (CART), calls for five, long-term field data collection sites. The first site, located in the Southern Great Plains (SGP) in Lamont, OK began operation in the spring of 1992. The CART Data Environment (CDE) is the element of the testbed which acquires the basic observations from the instruments and processes them to meet the ARM requirements. A formal design was used to develop a description of the logical requirements for the CDE. This paper discusses the design and prototype implementation of a part of the CDE known as the site operations log, which records metadata defining the environment within which the data produced by the instruments is collected

  1. RLV/X-33 operations overview

    Science.gov (United States)

    Black, Stephen T.; Eshleman, Wally

    1997-01-01

    This paper describes the VentureStar™ SSTO RLV and X-33 operations concepts. Applications of advanced technologies, automated ground support systems, advanced aircraft and launch vehicle lessons learned have been integrated to develop a streamlined vehicle and mission processing concept necessary to meet the goals of a commercial SSTO RLV. These concepts will be validated by the X-33 flight test program where financial and technical risk mitigation are required. The X-33 flight test program totally demonstrates the vehicle performance, technology, and efficient ground operations at the lowest possible cost. The Skunk Work's test program approach and test site proximity to the production plant are keys. The X-33 integrated flight and ground test program incrementally expands the knowledge base of the overall system allowing minimum risk progression to the next flight test program milestone. Subsequent X-33 turnaround processing flows will be performed with an aircraft operations philosophy. The differences will be based on research and development, component reliability and flight test requirements.

  2. Integrated safeguards and facility design and operations

    International Nuclear Information System (INIS)

    Tape, J.W.; Coulter, C.A.; Markin, J.T.; Thomas, K.E.

    1987-01-01

    The integration of safeguards functions to deter or detect unauthorized actions by an insider requires the careful communication and management of safeguards-relevant information on a timely basis. The traditional separation of safeguards functions into physical protection, materials control, and materials accounting often inhibits important information flows. Redefining the major safeguards functions as authorization, enforcement, and verification, and careful attention to management of information from acquisition to organization, to analysis, to decision making can result in effective safeguards integration. The careful inclusion of these ideas in facility designs and operations will lead to cost-effective safeguards systems. The safeguards authorization function defines, for example, personnel access requirements, processing activities, and materials movements/locations that are permitted to accomplish the mission of the facility. Minimizing the number of authorized personnel, limiting the processing flexibility, and maintaining up-to-date flow sheets will facilitate the detection of unauthorized activities. Enforcement of the authorized activities can be achieved in part through the use of barriers, access control systems, process sensors, and health and safety information. Consideration of safeguards requirements during facility design can improve the enforcement function. Verification includes the familiar materials accounting activities as well as auditing and testing of the other functions

  3. A new operational approach for solving fractional variational problems depending on indefinite integrals

    Science.gov (United States)

    Ezz-Eldien, S. S.; Doha, E. H.; Bhrawy, A. H.; El-Kalaawy, A. A.; Machado, J. A. T.

    2018-04-01

    In this paper, we propose a new accurate and robust numerical technique to approximate the solutions of fractional variational problems (FVPs) depending on indefinite integrals with a type of fixed Riemann-Liouville fractional integral. The proposed technique is based on the shifted Chebyshev polynomials as basis functions for the fractional integral operational matrix (FIOM). Together with the Lagrange multiplier method, these problems are then reduced to a system of algebraic equations, which greatly simplifies the solution process. Numerical examples are carried out to confirm the accuracy, efficiency and applicability of the proposed algorithm

  4. Substantial-Motivational Mechanism for Substantiation of Tolling Operations in Conditions of the European Integration

    OpenAIRE

    Melnyk Olga G; Kots Iryna I.

    2016-01-01

    The article is concerned with conceptualization of substance, distinguishing characteristics and motives of the implementation of tolling operations in conditions of the European integration. The study, based on the systematization and analysis of existing scientific approaches to definition of essence of tolling and tolling operations, has disclosed the dominating poli-positionality and ambiguity in this area. Economical autonomy of tolling operations has been determined, t...

  5. On controllability of an integrated bioreactor and periodically operated membrane separation process

    DEFF Research Database (Denmark)

    Prado Rubio, Oscar Andres; Jørgensen, Sten Bay; Jonsson, Gunnar Eigil

    the influence of membrane fouling. Previously, the REED and fermentation processes have been modeled and investigated separately (Prado- Rubio et al., 2011a; Boonmee, 2003). Additionally, a simple quasi-sequential strategy for integrated process design and control structure development has been proposed (Prado...... to understand the controlled operation of the integrated process, it is convenient to use a model based approach supported by experimental evidence. Recently, an integrated bioreactor and electrically driven membrane separation process (Reverse Electro- Enhanced Dialysis - REED) has been proposed as a method...... at a certain lactate concentration level. Hence, productivity can be enhanced by the in situ lactate removal from the cultivation broth during pH controlled fermentation. This can be done by means of ion exchange membranes and electrical potential gradients. The novelty of the integrated process lies...

  6. Integrated operations plan for the MFTF-B Mirror Fusion Test Facility. Volume I. Organization plan

    International Nuclear Information System (INIS)

    1981-12-01

    This plan and the accompanying MFTF-B Integrated Operations Plan are submitted in response to UC/LLNL Purchase Order 3883801, dated July 1981. The organization plan also addresses the specific tasks and trade studies directed by the scope of work. The Integrated Operations Plan, which includes a reliability, quality assurance, and safety plan and an integrated logistics plan, comprises the burden of the report. In the first section of this volume, certain underlying assumptions and observations are discussed setting the requirements and limits for organization. Section B presents the recommended structure itself. Section C Device Availability vs Maintenance and Support Efforts and Section D Staffing Levels and Skills provide backup detail and justification. Section E is a trade study on maintenance and support by LLNL staff vs subcontract and Section F is a plan for transitioning from the construction phase into operation. A brief summary of schedules and estimated costs concludes the volume

  7. Neurons with two sites of synaptic integration learn invariant representations.

    Science.gov (United States)

    Körding, K P; König, P

    2001-12-01

    Neurons in mammalian cerebral cortex combine specific responses with respect to some stimulus features with invariant responses to other stimulus features. For example, in primary visual cortex, complex cells code for orientation of a contour but ignore its position to a certain degree. In higher areas, such as the inferotemporal cortex, translation-invariant, rotation-invariant, and even view point-invariant responses can be observed. Such properties are of obvious interest to artificial systems performing tasks like pattern recognition. It remains to be resolved how such response properties develop in biological systems. Here we present an unsupervised learning rule that addresses this problem. It is based on a neuron model with two sites of synaptic integration, allowing qualitatively different effects of input to basal and apical dendritic trees, respectively. Without supervision, the system learns to extract invariance properties using temporal or spatial continuity of stimuli. Furthermore, top-down information can be smoothly integrated in the same framework. Thus, this model lends a physiological implementation to approaches of unsupervised learning of invariant-response properties.

  8. Operational Excellence through Schedule Optimization and Production Simulation of Application Specific Integrated Circuits.

    Energy Technology Data Exchange (ETDEWEB)

    Flory, John Andrew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Padilla, Denise D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gauthier, John H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Zwerneman, April Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Miller, Steven P [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-05-01

    Upcoming weapon programs require an aggressive increase in Application Specific Integrated Circuit (ASIC) production at Sandia National Laboratories (SNL). SNL has developed unique modeling and optimization tools that have been instrumental in improving ASIC production productivity and efficiency, identifying optimal operational and tactical execution plans under resource constraints, and providing confidence in successful mission execution. With ten products and unprecedented levels of demand, a single set of shared resources, highly variable processes, and the need for external supplier task synchronization, scheduling is an integral part of successful manufacturing. The scheduler uses an iterative multi-objective genetic algorithm and a multi-dimensional performance evaluator. Schedule feasibility is assessed using a discrete event simulation (DES) that incorporates operational uncertainty, variability, and resource availability. The tools provide rapid scenario assessments and responses to variances in the operational environment, and have been used to inform major equipment investments and workforce planning decisions in multiple SNL facilities.

  9. STAR Algorithm Integration Team - Facilitating operational algorithm development

    Science.gov (United States)

    Mikles, V. J.

    2015-12-01

    The NOAA/NESDIS Center for Satellite Research and Applications (STAR) provides technical support of the Joint Polar Satellite System (JPSS) algorithm development and integration tasks. Utilizing data from the S-NPP satellite, JPSS generates over thirty Environmental Data Records (EDRs) and Intermediate Products (IPs) spanning atmospheric, ocean, cryosphere, and land weather disciplines. The Algorithm Integration Team (AIT) brings technical expertise and support to product algorithms, specifically in testing and validating science algorithms in a pre-operational environment. The AIT verifies that new and updated algorithms function in the development environment, enforces established software development standards, and ensures that delivered packages are functional and complete. AIT facilitates the development of new JPSS-1 algorithms by implementing a review approach based on the Enterprise Product Lifecycle (EPL) process. Building on relationships established during the S-NPP algorithm development process and coordinating directly with science algorithm developers, the AIT has implemented structured reviews with self-contained document suites. The process has supported algorithm improvements for products such as ozone, active fire, vegetation index, and temperature and moisture profiles.

  10. Demosite - Demonstration of the integration of photovoltaic elements in buildings; DEMOSITE. Site de demonstration d'elements de construction photovoltaiques integres au batiment

    Energy Technology Data Exchange (ETDEWEB)

    Roecker, C.; Affolter, P.; Muller, A.N.; Ould-Yenia, A.

    2003-07-01

    This final report for the Swiss Federal Office of Energy summarises Phase 4 of the DEMOSITE project and concludes 10 years of DEMOSITE activities. The DEMOSITE project, started in 1992, demonstrates various ways of integrating photovoltaic elements in buildings by providing stands, pavilions and monitoring facilities at its site in Lausanne, Switzerland. Here, at the Swiss Federal Institute of Technology, roof-mounted installations can be found as well as mock-ups of buildings and roofing systems that also serve as covered parking facilities. The DEMOSITE web site and graphical presentations are also reviewed. Furthermore, the six newest pavilions are presented in detail. The report also presents several sets of data from measurements made on the installations and discusses the dissemination of information and results obtained from the project. A comprehensive annex provides illustrations of examples of building-integrated photovoltaics from around the world.

  11. Brand community integration and customer satisfaction of social media network sites among students

    Directory of Open Access Journals (Sweden)

    Hayford Amegbe

    2017-11-01

    Full Text Available The aim of the study was to examine how consumers integrate into brand communities on social media network sites (SNSs and how it affects overall satisfaction of social media sites users among students. The study depends on the service-dominant logic (SDL to develop the constructs for hypotheses testing. The study used a cross-sectional survey research design. The data were col-lected using a web-based survey of university of Nairobi Students. In all, a total of 608 students participated in the survey. The data was analyzed using structural equation modeling with AMOS software. The results revealed that frequency of usage of SNSs and duration of usage positively affect the self –perceived relevance of SNSs. Also, the self-perceived relevance leads to building brand community which finally leads to customer satisfaction. The research was limited to only students of Nairobi and selecting students in itself, which is a limitation as well as limiting it to uni-versity of Nairobi. The younger or the millennial are not the only users of SNSs. We have older generations as well, who also use SNSs for various activities such as professional development among others. Understanding why consumers of social media network site would integrate brand community is seminal for both local and foreign firms doing business in a developing country. This would enable marketing practitioners to craft marketing strategies best for community brand build-ing.

  12. The balanced scorecard advantage: Driving strategic change into Canada's nuclear laboratory site operations

    International Nuclear Information System (INIS)

    Lafreniere, P.; Weeks, D.

    2001-01-01

    The challenges presented by the size, diversity, complexity and history of the Facilities and Nuclear Operations (FNO) Group at AECL's Chalk River Laboratories (CRL) required a change to the traditional management approach. As a result, a strategy was adopted that focused on integrating contemporary business practices such as process mapping, activity based management and use of the Balanced Scorecard methodology into the operational culture at CRL. In addition, revitalization of the performance management methods process was undertaken to provide a tool for assessment of business and individual performance. performance. (author)

  13. Proposed plan for interim remedial measures at the 100-HR-1 Operable Unit, Hanford Site, Richland, Washington. Draft A

    International Nuclear Information System (INIS)

    1994-09-01

    This proposed plan introduces the interim remedial measures for addressing contaminated soil at the 100-HR-1 Operable Unit, located at the Hanford Site. In addition, this plan includes a summary of other alternatives analyzed and considered for the 100-HR-1 Operable Unit. The EPA, DOE, and Washington State Dept. of Ecology believe that a combination of removal, treatment, and disposal technologies, where appropriate, would significantly reduce the potential threats to human health and the environment at the 100-HR-1 Operable Unit high-priority waste sites. The remedial actions described in this proposed plan are designed to minimize human health and ecological risks and ensure that additional contaminants originating from these waste sites are not transported to the groundwater. The 100-HR-1 Operable Unit contains the retention basin for the H reactor cooling system, process effluent trenches, the Pluto crib which received an estimated 260 gallons of radioactive liquid waste, process effluent pipelines, and solid waste sites used for the burial of decontaminated and decommissioned equipment from other facilities. Potential health threats would be from the isotopes of cesium, cobalt, europium, plutonium, and strontium, and from chromium, arsenic, lead, and chysene

  14. Pre-operative urinary tract infection: is it a risk factor for early surgical site infection with hip fracture surgery? A retrospective analysis.

    Science.gov (United States)

    Yassa, Rafik Rd; Khalfaoui, Mahdi Y; Veravalli, Karunakar; Evans, D Alun

    2017-03-01

    The aims of the current study were to determine whether pre-operative urinary tract infections in patients presenting acutely with neck of femur fractures resulted in a delay to surgery and whether such patients were at increased risk of developing post-operative surgical site infections. A retrospective review of all patients presenting with a neck of femur fracture, at a single centre over a one-year period. The hospital hip fracture database was used as the main source of data. UK University Teaching Hospital. All patients ( n  = 460) presenting across a single year study period with a confirmed hip fracture. The presence of pre-operative urinary tract infection, the timing of surgical intervention, the occurrence of post-operative surgical site infection and the pathogens identified. A total of 367 patients were operated upon within 24 hours of admission. Urinary infections were the least common cause of delay. A total of 99 patients (21.5%) had pre-operative urinary tract infection. Post-operatively, a total of 57 (12.4%) patients developed a surgical site infection. Among the latter, 31 (54.4%) did not have a pre-operative urinary infection, 23 (40.4%) patients had a pre-operative urinary tract infection, 2 had chronic leg ulcers and one patient had a pre-operative chest infection. Statistically, there was a strong relationship between pre-operative urinary tract infection and the development of post-operative surgical site infection ( p -value: 0.0005). The results of our study indicate that pre-operative urinary tract infection has a high prevalence amongst those presenting with neck of femur fractures, and this is a risk factor for the later development of post-operative surgical site infection.

  15. Preliminary site design for the SP-100 ground engineering test

    International Nuclear Information System (INIS)

    Cox, C.M.; Miller, W.C.; Mahaffey, M.K.

    1986-04-01

    In November, 1985, Hanford was selected by the Department of Energy (DOE) as the preferred site for a full-scale test of the integrated nuclear subsystem for SP-100. The Hanford Engineering Development Laboratory, operated by Westinghouse Hanford Company, was assigned as the lead contractor for the Test Site. The nuclear subsystem, which includes the reactor and its primary heat transport system, will be provided by the System Developer, another contractor to be selected by DOE in late FY-1986. In addition to reactor operations, test site responsibilities include preparation of the facility plus design, procurement and installation of a vacuum chamber to house the reactor, a secondary heat transport system to dispose of the reactor heat, a facility control system, and postirradiation examination. At the conclusion of the test program, waste disposal and facility decommissioning are required. The test site must also prepare appropriate environmental and safety evaluations. This paper summarizes the preliminary design requirements, the status of design, and plans to achieve full power operation of the test reactor in September, 1990

  16. NASA Research on an Integrated Concept for Airport Surface Operations Management

    Science.gov (United States)

    Gupta, Gautam

    2012-01-01

    Surface operations at airports in the US are based on tactical operations, where departure aircraft primarily queue up and wait at the departure runways. There have been attempts to address the resulting inefficiencies with both strategic and tactical tools for metering departure aircraft. This presentation gives an overview of Spot And Runway Departure Advisor with Collaborative Decision Making (SARDA-CDM): an integrated strategic and tactical system for improving surface operations by metering departure aircraft. SARDA-CDM is the augmentation of ground and local controller advisories through sharing of flight movement and related operations information between airport operators, flight operators and air traffic control at the airport. The goal is to enhance the efficiency of airport surface operations by exchanging information between air traffic control and airline operators, while minimizing adverse effects on stakeholders and passengers. The presentation motivates the need for departure metering, and provides a brief background on the previous work on SARDA. Then, the concept of operations for SARDA-CDM is described. Then the preliminary results from testing the concept in a real-time automated simulation environment are described. Results indicate benefits such as reduction in taxiing delay and fuel consumption. Further, the preliminary implementation of SARDA-CDM seems robust for two minutes delay in gate push-back times.

  17. The role of short-range Cys171-Cys178 disulfide bond in maintaining cutinase active site integrity: A molecular dynamics simulation

    International Nuclear Information System (INIS)

    Matak, Mehdi Youssefi; Moghaddam, Majid Erfani

    2009-01-01

    Understanding structural determinants in enzyme active site integrity can provide a good knowledge to design efficient novel catalytic machineries. Fusarium solani pisi cutinase with classic triad Ser-His-Asp is a promising enzyme to scrutinize these structural determinants. We performed two MD simulations: one, with the native structure, and the other with the broken Cys171-Cys178 disulfide bond. This disulfide bond stabilizes a turn in active site on which catalytic Asp175 is located. Functionally important H-bonds and atomic fluctuations in catalytic pocket have been changed. We proposed that this disulfide bond within active site can be considered as an important determinant of cutinase active site structural integrity.

  18. An Integrated Assessment of Location-Dependent Scaling for Microalgae Biofuel Production Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, Andre M.; Abodeely, Jared; Skaggs, Richard; Moeglein, William AM; Newby, Deborah T.; Venteris, Erik R.; Wigmosta, Mark S.

    2014-06-19

    Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting/design through processing/upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are addressed in part by applying the Integrated Assessment Framework (IAF)—an integrated multi-scale modeling, analysis, and data management suite—to address key issues in developing and operating an open-pond facility by analyzing how variability and uncertainty in space and time affect algal feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. The IAF was applied to a set of sites previously identified as having the potential to cumulatively produce 5 billion-gallons/year in the southeastern U.S. and results indicate costs can be reduced by selecting the most effective processing technology pathway and scaling downstream processing capabilities to fit site-specific growing conditions, available resources, and algal strains.

  19. Optimal Operation and Stabilising Control of the Concentric Heat-Integrated Distillation Column

    DEFF Research Database (Denmark)

    Bisgaard, Thomas; Skogestad, Sigurd; Huusom, Jakob Kjøbsted

    2016-01-01

    A systematic control structure design method is applied on the concentric heat integrated distillation column (HIDiC) separating benzene and toluene. A degrees of freedom analysis is provided for identifying potential manipulated and controlled variables. Optimal operation is mapped and active...

  20. Virus-Clip: a fast and memory-efficient viral integration site detection tool at single-base resolution with annotation capability.

    Science.gov (United States)

    Ho, Daniel W H; Sze, Karen M F; Ng, Irene O L

    2015-08-28

    Viral integration into the human genome upon infection is an important risk factor for various human malignancies. We developed viral integration site detection tool called Virus-Clip, which makes use of information extracted from soft-clipped sequencing reads to identify exact positions of human and virus breakpoints of integration events. With initial read alignment to virus reference genome and streamlined procedures, Virus-Clip delivers a simple, fast and memory-efficient solution to viral integration site detection. Moreover, it can also automatically annotate the integration events with the corresponding affected human genes. Virus-Clip has been verified using whole-transcriptome sequencing data and its detection was validated to have satisfactory sensitivity and specificity. Marked advancement in performance was detected, compared to existing tools. It is applicable to versatile types of data including whole-genome sequencing, whole-transcriptome sequencing, and targeted sequencing. Virus-Clip is available at http://web.hku.hk/~dwhho/Virus-Clip.zip.

  1. Optimation of Operation System Integration between Main and Feeder Public Transport (Case Study: Trans Jakarta-Kopaja Bus Services)

    Science.gov (United States)

    Miharja, M.; Priadi, Y. N.

    2018-05-01

    Promoting a better public transport is a key strategy to cope with urban transport problems which are mostly caused by a huge private vehicle usage. A better public transport service quality not only focuses on one type of public transport mode, but also concerns on inter modes service integration. Fragmented inter mode public transport service leads to a longer trip chain as well as average travel time which would result in its failure to compete with a private vehicle. This paper examines the optimation process of operation system integration between Trans Jakarta Bus as the main public transport mode and Kopaja Bus as feeder public transport service in Jakarta. Using scoring-interview method combined with standard parameters in operation system integration, this paper identifies the key factors that determine the success of the two public transport operation system integrations. The study found that some key integration parameters, such as the cancellation of “system setoran”, passenger get in-get out at official stop points, and systematic payment, positively contribute to a better service integration. However, some parameters such as fine system, time and changing point reliability, and information system reliability are among those which need improvement. These findings are very useful for the authority to set the right strategy to improve operation system integration between Trans Jakarta and Kopaja Bus services.

  2. Operational Circular No. 2 (Rev. 3) - Conditions of access to the fenced parts of the CERN site

    CERN Multimedia

    HR Department

    2015-01-01

    Operational Circular No. 2 (Rev. 3) entitled "Conditions of access to the fenced parts of the CERN site", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 24 September 2015, is now available via this link.   This revised circular cancels and replaces Operational Circular No. 2 (Rev. 2) also entitled "Conditions of access to the fenced parts of the CERN site", of September 2014. The circular was revised predominantly in order to specify that access to the CERN site is granted to CERN Pension Fund beneficiaries only provided that they are actually in receipt of payments from the Fund; and to allow the Director-General to permit special types of vehicles on site, such as trailers. It also includes a certain number of text improvements and an updated version of the implementation measures, in particular with regard to vehicle identification, road traffic and parking.  

  3. US Department of Energy, Richland Operations Office Integrated Safety Management System Program Description

    International Nuclear Information System (INIS)

    SHOOP, D.S.

    2000-01-01

    The purpose of this Integrated Safety Management System (ISMS) Program Description (PD) is to describe the U.S. Department of Energy (DOE), Richland Operations Office (RL) ISMS as implemented through the RL Integrated Management System (RIMS). This PD does not impose additional requirements but rather provides an overview describing how various parts of the ISMS fit together. Specific requirements for each of the core functions and guiding principles are established in other implementing processes, procedures, and program descriptions that comprise RIMS. RL is organized to conduct work through operating contracts; therefore, it is extremely difficult to provide an adequate ISMS description that only addresses RL functions. Of necessity, this PD contains some information on contractor processes and procedures which then require RL approval or oversight

  4. Operative integration to the first collective agreement 1998-2003

    International Nuclear Information System (INIS)

    2004-01-01

    The article describes the process followed from the time of Operational Integration of the two AIEs-ANA and CNV II-which operated the Asco-I and II and Vandellos-II nuclear power plants, and and the merger of these two ventures up to the signing of a single Collective Agreement that, in the framework of labor-relations, allowed for a process of consolidation that gave rise to unified corporate regulation and planning of human resources. In 1998 , the year in which the process began, there were two companies-ANA and CNV II-with two Collective Agreements, two Pension Plans and two Corporate Headquarters located in Barcelona. Now there is only one company-ANAV-with a single Collective Agreement a single Pension Plan with two sub-plans, and generational changeover in its final phase with the target staff and no excess. (Author)

  5. SELF-CONSISTENT,INTEGRATED,ADVANCED TOKAMAK OPERATION ON DIII-D

    International Nuclear Information System (INIS)

    WADE, MR; MURAKAMI, M; LUCE, TC; FERRON, JR; PETTY, CC; BRENNAN, DP; GAROFALO, AM; GREENFIELD, CM; HYATT, AW; JAYAKUMAR, R; LAHAYE, RJ; LAO, LL; LOHR, J; POLITZER, PA; PRATER, R; STRAIT, EJ

    2002-01-01

    Recent experiments on DIII-D have demonstrated the ability to sustain plasma conditions that integrate and sustain the key ingredients of Advanced Tokamak (AT) operation: high β with q min >> 1, good energy confinement, and high current drive efficiency. Utilizing off-axis (ρ 0.4) electron cyclotron current drive (ECCD) to modify the current density profile in a plasma operating near the no-wall ideal stability limit with q min > 2.0, plasmas with β = 2.9% and 90% of the plasma current driven non-inductively have been sustained for nearly 2 s (limited only by the duration of the ECCD pulse). Separate experiments have demonstrated the ability to sustain a steady current density profile using ECCD for periods as long as 1 s with β = 3.3% and > 90% of the current driven non-inductively

  6. Some interactive factors affecting trench-cover integrity on low-level waste sites

    International Nuclear Information System (INIS)

    Hakonson, T.E.; Lane, L.J.; Steger, J.G.; DePoorter, G.L.

    1982-01-01

    This paper describes important mechanisms by which radionuclide can be transported from low-level waste disposal sites into biological pathways, discuss interactions of abiotic and biotic processes, and recommends environmental characteristics that should be measured to design sites that minimize this transport. Past experience at shallow land burial sites for low-level radioactive wastes suggest that occurrences of waste exposure and radionuclide transport are often related to inadequate trench cover designs. Meeting performance standards at low-level waste sites can only be achieved by recognizing that physical, chemical, and biological processes operating on and in a trench cover profile are highly interactive. Failure to do so can lead to improper design criteria and subsequent remedial action procedures that can adversely affect site stability. Based upon field experiments and computer modeling, recommendations are made on site characteristics that require measurement in order to design systems that reduce surface runoff and erosion, manage soil moisture and biota in the cover profile to maximize evapotranspiration and minimize percolation, and place bounds on the intrusion potential of plants and animals into the waste material. Major unresolved problems include developing probabilistic approaches that include climatic variability, improved knowledge of soil-water-plant-erosion relationships, development of practical vegetation establishment and maintenance procedures, prediction and quantification of site potential and plant succession, and understanding the interaction of processes occurring on and in the cover profile with deeper subsurface processes

  7. Incidence of surgical site infection with pre-operative skin preparation using 10% polyvidone-iodine and 0.5% chlorhexidine-alcohol.

    Science.gov (United States)

    Rodrigues, Ana Luzia; Simões, Maria de Lourdes Pessole Biondo

    2013-01-01

    To analyze the incidence of surgical site infection when the preoperative skin preparation was performed with 10% povidone-iodine and 0.5% chlorhexidine-alcohol. We conducted a randomized, longitudinal study based on variables obtained from patients undergoing clean and potentially contaminated operations. Those involved were divided into two groups. In group 1 (G1) we included 102 patients with skin prepared with povidone-iodine, and in group 2 (G2), 103, whose skin was prepared with chlorhexidine. In the third, seventh and 30th postoperative days we evaluated the surgical site, searching for signs of infection. Data related to clinical profile, such as diabetes mellitus, smoking, alcoholism, haematological data (Hb, VG and leukocytes), age and gender, and the related variables, such as number of days of preoperative hospitalization, shaving, topography of incision, antibiotic prophylaxis and resident participation in the operation were not predisposing factors for surgical site infection. Two patients in G1 and eight in G2 undergoing clean operations had some type of infection (p = 0.1789), five in G1 and three in G2 undergoing potentially contaminated operations had some type of infection (p = 0.7205). The incidence of surgical site infection in operations classified as clean and as potentially contaminated for which skin preparation was done with 10% povidone-iodine and 0.5% chlorhexidine-alcohol was similar.

  8. Validation and Verification of Future Integrated Safety-Critical Systems Operating under Off-Nominal Conditions

    Science.gov (United States)

    Belcastro, Christine M.

    2010-01-01

    Loss of control remains one of the largest contributors to aircraft fatal accidents worldwide. Aircraft loss-of-control accidents are highly complex in that they can result from numerous causal and contributing factors acting alone or (more often) in combination. Hence, there is no single intervention strategy to prevent these accidents and reducing them will require a holistic integrated intervention capability. Future onboard integrated system technologies developed for preventing loss of vehicle control accidents must be able to assure safe operation under the associated off-nominal conditions. The transition of these technologies into the commercial fleet will require their extensive validation and verification (V and V) and ultimate certification. The V and V of complex integrated systems poses major nontrivial technical challenges particularly for safety-critical operation under highly off-nominal conditions associated with aircraft loss-of-control events. This paper summarizes the V and V problem and presents a proposed process that could be applied to complex integrated safety-critical systems developed for preventing aircraft loss-of-control accidents. A summary of recent research accomplishments in this effort is also provided.

  9. A Concept of Operations for an Integrated Vehicle Health Assurance System

    Science.gov (United States)

    Hunter, Gary W.; Ross, Richard W.; Berger, David E.; Lekki, John D.; Mah, Robert W.; Perey, Danie F.; Schuet, Stefan R.; Simon, Donald L.; Smith, Stephen W.

    2013-01-01

    This document describes a Concept of Operations (ConOps) for an Integrated Vehicle Health Assurance System (IVHAS). This ConOps is associated with the Maintain Vehicle Safety (MVS) between Major Inspections Technical Challenge in the Vehicle Systems Safety Technologies (VSST) Project within NASA s Aviation Safety Prog